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Overview

ID MAG01654
Name HFD2_bin.46
Sample SMP0044
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Alphaproteobacteria
Order Micropepsales
Family Micropepsaceae
Genus CAIYRG01
Species
Assembly information
Completeness (%) 90.55
Contamination (%) 2.77
GC content (%) 62.0
N50 (bp) 25,021
Genome size (bp) 4,568,511

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes4205

Gene name Description KEGG GOs EC E-value Score Sequence
HFD2_k127_1009745_0 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007221 474.0
HFD2_k127_1009745_1 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000531 133.0
HFD2_k127_1035720_0 C-terminal, D2-small domain, of ClpB protein K03695 - - 0.0 1304.0
HFD2_k127_1035720_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 1.324e-233 740.0
HFD2_k127_1035720_10 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003127 326.0
HFD2_k127_1035720_11 PFAM amidohydrolase 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002225 276.0
HFD2_k127_1035720_12 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.00000000000000000000000000000000000000000000000000000000000000000000000006174 274.0
HFD2_k127_1035720_13 PepSY-associated TM region - - - 0.000000000000000000000000000000000000000000000000000000000000000005479 239.0
HFD2_k127_1035720_14 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000009053 219.0
HFD2_k127_1035720_15 response to cobalt ion - GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0010045,GO:0010243,GO:0030288,GO:0030313,GO:0031975,GO:0032025,GO:0033554,GO:0042221,GO:0042597,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:1901652,GO:1901698,GO:1901700 - 0.00000000000000000000000000000000000000000000000000000001322 207.0
HFD2_k127_1035720_16 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.000000000000000000000000000000000000000000000000000174 191.0
HFD2_k127_1035720_17 Uncharacterised protein conserved in bacteria (DUF2336) - - - 0.0000000000000000000000000000000000000000000000000002631 199.0
HFD2_k127_1035720_18 transglycosylase - - - 0.0000000000000000000000000000000000000000000000000003283 197.0
HFD2_k127_1035720_19 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000000000000000293 157.0
HFD2_k127_1035720_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 1.753e-232 743.0
HFD2_k127_1035720_20 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases - - - 0.00000000000000000000000000000000002056 138.0
HFD2_k127_1035720_21 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.0000000000000000000000000000000001536 146.0
HFD2_k127_1035720_22 Cell Wall Hydrolase - - - 0.0000000000000000000000000004497 119.0
HFD2_k127_1035720_23 CDP-alcohol phosphatidyltransferase - - - 0.000000000000000000000000003172 123.0
HFD2_k127_1035720_24 Domain of unknown function (DUF4167) - - - 0.000000000000000000000171 101.0
HFD2_k127_1035720_25 Cupin - - - 0.0000000000000000001145 95.0
HFD2_k127_1035720_26 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K12980 - - 0.00009655 52.0
HFD2_k127_1035720_3 von Willebrand factor, type A K07114 - - 1.083e-212 683.0
HFD2_k127_1035720_4 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008775 540.0
HFD2_k127_1035720_5 PFAM Prokaryotic protein of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 525.0
HFD2_k127_1035720_6 PQQ-like domain K05889 - 1.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007299 527.0
HFD2_k127_1035720_7 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000707 437.0
HFD2_k127_1035720_8 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 362.0
HFD2_k127_1035720_9 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K05939 - 2.3.1.40,6.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006663 329.0
HFD2_k127_1044828_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1160.0
HFD2_k127_1044828_1 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 429.0
HFD2_k127_1044828_2 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 336.0
HFD2_k127_1044828_3 Peptidase M16 inactive domain K07263,K07623 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003566 333.0
HFD2_k127_1044828_4 Putative diguanylate phosphodiesterase K13593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 298.0
HFD2_k127_1044828_5 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007933 266.0
HFD2_k127_1044828_6 COG2030 Acyl dehydratase K17865 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016043,GO:0016829,GO:0016835,GO:0016836,GO:0022607,GO:0042620,GO:0042621,GO:0043933,GO:0044085,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901576 4.2.1.55 0.0000000000000000000000000000000000000000000001518 172.0
HFD2_k127_1044828_7 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000003836 153.0
HFD2_k127_1044828_8 Protein of unknown function (DUF3035) - - - 0.0000000000000003525 87.0
HFD2_k127_1044828_9 protein conserved in bacteria K09924 - - 0.0002177 51.0
HFD2_k127_1065764_0 AMP-binding enzyme K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006039 426.0
HFD2_k127_1065764_1 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006541 397.0
HFD2_k127_1065764_10 amino acid K01999 - - 0.00000000001513 71.0
HFD2_k127_1065764_2 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 336.0
HFD2_k127_1065764_3 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 314.0
HFD2_k127_1065764_4 Rieske 2Fe-2S K19982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001565 287.0
HFD2_k127_1065764_5 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002889 259.0
HFD2_k127_1065764_6 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000005008 243.0
HFD2_k127_1065764_7 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000007353 234.0
HFD2_k127_1065764_8 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000001836 203.0
HFD2_k127_1065764_9 COG1846 Transcriptional regulators - - - 0.000000000000003314 86.0
HFD2_k127_1081224_0 Uncharacterized protein family (UPF0051) K09014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 352.0
HFD2_k127_1081224_1 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000006817 182.0
HFD2_k127_1081224_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000001514 75.0
HFD2_k127_1093404_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 3.107e-314 982.0
HFD2_k127_1093404_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 1.624e-287 899.0
HFD2_k127_1093404_10 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007775 462.0
HFD2_k127_1093404_11 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007743 439.0
HFD2_k127_1093404_12 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003591 430.0
HFD2_k127_1093404_13 Belongs to the ribose-phosphate pyrophosphokinase family K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 357.0
HFD2_k127_1093404_14 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 332.0
HFD2_k127_1093404_15 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 296.0
HFD2_k127_1093404_16 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004241 280.0
HFD2_k127_1093404_17 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004289 281.0
HFD2_k127_1093404_18 helix_turn_helix, Lux Regulon K14987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000047 259.0
HFD2_k127_1093404_19 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003909 252.0
HFD2_k127_1093404_2 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 1.933e-223 711.0
HFD2_k127_1093404_20 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000007924 243.0
HFD2_k127_1093404_21 helix_turn_helix, cAMP Regulatory protein K01420,K15861 - - 0.000000000000000000000000000000000000000000000000000005158 199.0
HFD2_k127_1093404_22 Ion channel - - - 0.00000000000000000000000000000000000000000000000002668 184.0
HFD2_k127_1093404_23 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000000000000000009464 179.0
HFD2_k127_1093404_24 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000004562 172.0
HFD2_k127_1093404_25 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.000000000000000000000000000000000000000000587 166.0
HFD2_k127_1093404_26 - - - - 0.000000000000000000000000000000000000000001902 158.0
HFD2_k127_1093404_27 Transglycosylase associated protein - - - 0.000000000000000000000000000000000000000004625 156.0
HFD2_k127_1093404_28 PFAM pyridoxamine 5-phosphate oxidase-related FMN-binding - - - 0.00000000000000000000000000000000000000001781 158.0
HFD2_k127_1093404_29 Catalyzes the transfer of an acetyl group from acetyl- CoA to the 6'-amino group of aminoglycoside molecules conferring resistance to antibiotics containing the purpurosamine ring K18816 GO:0003674,GO:0003824,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0034069,GO:0042221,GO:0046677,GO:0047663,GO:0050896 2.3.1.82 0.000000000000000000000000000000000005951 145.0
HFD2_k127_1093404_3 Thymidine phosphorylase K00758 - 2.4.2.4 1.038e-197 630.0
HFD2_k127_1093404_30 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000002042 147.0
HFD2_k127_1093404_31 tetratricopeptide repeat - - - 0.00000000000000000000000000000000003067 145.0
HFD2_k127_1093404_32 - - - - 0.00000000000000000000000000000000007242 139.0
HFD2_k127_1093404_33 cheY-homologous receiver domain - - - 0.000000000000000000000000000000003075 132.0
HFD2_k127_1093404_34 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000311 134.0
HFD2_k127_1093404_36 Cytochrome c - - - 0.00000000000000000000000000256 115.0
HFD2_k127_1093404_37 phosphorelay signal transduction system - - - 0.00000000000000001285 88.0
HFD2_k127_1093404_38 Cytochrome c - - - 0.00000000000000001822 86.0
HFD2_k127_1093404_39 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0000000000000000624 84.0
HFD2_k127_1093404_4 exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 7.204e-197 622.0
HFD2_k127_1093404_40 - - - - 0.0000000000000221 79.0
HFD2_k127_1093404_41 Domain of unknown function (DUF4115) K15539 - - 0.00000000000003825 85.0
HFD2_k127_1093404_42 methylesterase K13924 - 2.1.1.80,3.1.1.61 0.000000003743 64.0
HFD2_k127_1093404_5 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007558 595.0
HFD2_k127_1093404_6 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 573.0
HFD2_k127_1093404_7 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639,K00652,K00654 - 2.3.1.29,2.3.1.47,2.3.1.50 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 546.0
HFD2_k127_1093404_8 4-alpha-glucanotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 545.0
HFD2_k127_1093404_9 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 535.0
HFD2_k127_1143547_0 O-acetylhomoserine K01738,K01740 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003961,GO:0004124,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006555,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0017144,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0050667,GO:0071265,GO:0071266,GO:0071268,GO:0071269,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47,2.5.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 552.0
HFD2_k127_1143547_1 Enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 323.0
HFD2_k127_1143547_2 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000002648 259.0
HFD2_k127_1143547_3 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004193 244.0
HFD2_k127_1143547_4 CoA binding domain K06929 - - 0.000000000000000000000000000000000000000000000000000000000000001959 221.0
HFD2_k127_1143547_5 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000000000000000000006264 218.0
HFD2_k127_1172142_0 Sugar (and other) transporter K08178 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 494.0
HFD2_k127_1172142_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006255 265.0
HFD2_k127_1172142_2 Oligopeptidase F K08602 - - 0.0000000000000000000000000000000003959 140.0
HFD2_k127_1195851_0 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000002352 117.0
HFD2_k127_1195851_1 - - - - 0.00000000000000000000000018 117.0
HFD2_k127_1248148_0 ABC transporter transmembrane region K06147 - - 6.523e-199 636.0
HFD2_k127_1248148_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0030060,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 518.0
HFD2_k127_1248148_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 453.0
HFD2_k127_1248148_3 tRNA (Guanine-1)-methyltransferase K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 332.0
HFD2_k127_1248148_4 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000005932 176.0
HFD2_k127_1248148_5 Ribosomal protein S16 K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000067 156.0
HFD2_k127_1248148_6 RimM N-terminal domain K02860 - - 0.00000000000000000000000000000000000000006786 162.0
HFD2_k127_130515_1 Amidohydrolase K03392,K10220 - 4.1.1.45,4.2.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000366 548.0
HFD2_k127_130515_10 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 317.0
HFD2_k127_130515_11 Domain of unknown function (DUF1932) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004677 273.0
HFD2_k127_130515_12 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000006782 258.0
HFD2_k127_130515_13 Ndr family K14727 - 3.1.1.24,4.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000004503 241.0
HFD2_k127_130515_14 Pfam Cupin K00450,K11948 - 1.13.11.38,1.13.11.4 0.0000000000000000000000000000000000000000000000000000000000000000003671 243.0
HFD2_k127_130515_15 Class II Aldolase and Adducin N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000004997 236.0
HFD2_k127_130515_16 Aromatic-ring-opening dioxygenase LigAB, LigA subunit K04100 - 1.13.11.8 0.00000000000000000000000000000000000000000000000000003183 190.0
HFD2_k127_130515_17 - - - - 0.00000000000000000000000000000000000000000000000000308 188.0
HFD2_k127_130515_18 Serine aminopeptidase, S33 K01055 - 3.1.1.24 0.0000000000000000000000000000000000000000000000000608 188.0
HFD2_k127_130515_19 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000797 176.0
HFD2_k127_130515_2 ornithine cyclodeaminase K01750 - 4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 516.0
HFD2_k127_130515_20 Domain of unknown function (DUF4399) - - - 0.000000000000000000000000000000000000000001746 162.0
HFD2_k127_130515_21 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000002408 162.0
HFD2_k127_130515_22 Protein of unknown function (DUF1109) - - - 0.000000000000000000000000000000000000004816 153.0
HFD2_k127_130515_23 - - - - 0.0000000000000000000000000000000000005081 149.0
HFD2_k127_130515_24 Transcriptional regulator K16137 - - 0.000000000000000000000000000000000007307 145.0
HFD2_k127_130515_25 Putative DNA-binding domain - - - 0.0000000000000000000000000000000004539 141.0
HFD2_k127_130515_26 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000004668 114.0
HFD2_k127_130515_27 TfoX N-terminal domain - - - 0.0000000000000000000000002458 109.0
HFD2_k127_130515_28 DoxX - - - 0.0000000000000000000000004053 110.0
HFD2_k127_130515_29 Predicted integral membrane protein (DUF2282) - - - 0.000000000000000003536 90.0
HFD2_k127_130515_3 Amidohydrolase K10221 - 3.1.1.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 450.0
HFD2_k127_130515_30 Transposase IS116/IS110/IS902 family K07486 - - 0.0000000007458 59.0
HFD2_k127_130515_4 Catalytic LigB subunit of aromatic ring-opening dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 439.0
HFD2_k127_130515_5 NMT1/THI5 like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003848 368.0
HFD2_k127_130515_6 Belongs to the GST superfamily K00799,K11209 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 353.0
HFD2_k127_130515_7 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 346.0
HFD2_k127_130515_8 COG0684 Demethylmenaquinone methyltransferase K10218 - 4.1.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 320.0
HFD2_k127_130515_9 belongs to the UPF0276 family K09930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 325.0
HFD2_k127_1306555_0 Phage tail sheath C-terminal domain K06907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 607.0
HFD2_k127_1306555_1 Rhs element vgr protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 506.0
HFD2_k127_1306555_10 Baseplate J-like protein - - - 0.000000000000000000000000000000000000000001103 160.0
HFD2_k127_1306555_11 - - - - 0.00000000000000000000000000000000000000001007 156.0
HFD2_k127_1306555_12 hydrolase (HAD superfamily) K01560 - 3.8.1.2 0.000000000000000000000007657 102.0
HFD2_k127_1306555_2 peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 484.0
HFD2_k127_1306555_3 LysM domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009284 312.0
HFD2_k127_1306555_4 May be involved in the transport of PQQ or its precursor to the periplasm - - - 0.000000000000000000000000000000000000000000000000000000000003427 224.0
HFD2_k127_1306555_5 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000000000000000000000001348 207.0
HFD2_k127_1306555_6 peroxidase K07223 - - 0.0000000000000000000000000000000000000000000000000000002523 201.0
HFD2_k127_1306555_7 - - - - 0.000000000000000000000000000000000000000000000000000249 192.0
HFD2_k127_1306555_8 T4-like virus tail tube protein gp19 - - - 0.0000000000000000000000000000000000000000000000000002802 188.0
HFD2_k127_1306555_9 Gene 25-like lysozyme K06903 - - 0.000000000000000000000000000000000000000000000000001753 187.0
HFD2_k127_1325828_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1086.0
HFD2_k127_1325828_1 PFAM Amylo-alpha-16-glucosidase - - - 1.656e-244 775.0
HFD2_k127_1325828_10 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.0000000000000000000000000000000001258 145.0
HFD2_k127_1325828_11 - - - - 0.000000000000000000000001367 108.0
HFD2_k127_1325828_12 - - - - 0.0000000000007527 71.0
HFD2_k127_1325828_13 decarboxylase K01607 - 4.1.1.44 0.00000002479 57.0
HFD2_k127_1325828_14 - - - - 0.0001298 51.0
HFD2_k127_1325828_15 Sodium:sulfate symporter transmembrane region K03319,K14445 - - 0.0005274 48.0
HFD2_k127_1325828_16 Cytochrome c - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0006633 47.0
HFD2_k127_1325828_2 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008863 576.0
HFD2_k127_1325828_3 Glycosyltransferase Family 4 K12995 - 2.4.1.348 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003664 459.0
HFD2_k127_1325828_4 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 446.0
HFD2_k127_1325828_5 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000713 348.0
HFD2_k127_1325828_6 ABC transporter K05847 GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0031460,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0072337 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007205 295.0
HFD2_k127_1325828_7 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001429 284.0
HFD2_k127_1325828_8 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000007249 186.0
HFD2_k127_1325828_9 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.0000000000000000000000000000000000000000000007277 180.0
HFD2_k127_139423_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 540.0
HFD2_k127_139423_1 nuclear chromosome segregation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009873 314.0
HFD2_k127_139423_10 IgA Peptidase M64 - - - 0.0000000001506 73.0
HFD2_k127_139423_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000013 276.0
HFD2_k127_139423_3 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000452 246.0
HFD2_k127_139423_4 Arylesterase - - - 0.000000000000000000000000000000000008266 140.0
HFD2_k127_139423_5 decarboxylase K01607 - 4.1.1.44 0.000000000000000000000000000000000112 141.0
HFD2_k127_139423_6 PFAM SMP-30 Gluconolaconase LRE-like region K01053 - 3.1.1.17 0.00000000000000000000000000007805 124.0
HFD2_k127_139423_7 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.0000000000000000000000000001167 128.0
HFD2_k127_139423_8 sterol desaturase - - - 0.0000000000000000000000002513 117.0
HFD2_k127_139423_9 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000001286 100.0
HFD2_k127_1406463_0 decarboxylase K01607 - 4.1.1.44 0.000000000000000000004665 106.0
HFD2_k127_1406463_1 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K01607 - 4.1.1.44 0.000000000000000000008425 105.0
HFD2_k127_141616_0 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004345 407.0
HFD2_k127_141616_1 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 330.0
HFD2_k127_141616_2 PFAM integrase family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002854 267.0
HFD2_k127_141616_3 dienelactone hydrolase - - - 0.000000000000000000000000000000000000001783 156.0
HFD2_k127_141616_4 Structurally related to pyridoxine 5''-phosphate oxidase K07006 - - 0.000000000000000000004241 93.0
HFD2_k127_147684_0 peptidase M20 - - - 1.284e-211 668.0
HFD2_k127_147684_1 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003244 548.0
HFD2_k127_147684_10 Copper resistance protein K07156 - - 0.0000000000000002143 90.0
HFD2_k127_147684_11 receptor K02014 - - 0.00000002668 66.0
HFD2_k127_147684_2 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 440.0
HFD2_k127_147684_3 dehydrogenases and related proteins K10219 - 1.1.1.312 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 437.0
HFD2_k127_147684_4 Protein of unknown function (DUF418) K07148 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 428.0
HFD2_k127_147684_5 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008184 367.0
HFD2_k127_147684_6 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000002287 208.0
HFD2_k127_147684_7 Copper resistance protein D K07245 - - 0.000000000000000000000000000000000000000000000000000000002416 211.0
HFD2_k127_147684_8 LTXXQ motif family protein - - - 0.0000000000000000000000000000000000002288 147.0
HFD2_k127_147684_9 Cytochrome c K08738 - - 0.0000000000000000006177 91.0
HFD2_k127_1490691_0 homogentisate 1,2-dioxygenase K00451 - 1.13.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 602.0
HFD2_k127_1490691_1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal K00457 - 1.13.11.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 508.0
HFD2_k127_1490691_2 Fumarylacetoacetate (FAA) hydrolase family K16171 - 3.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008872 374.0
HFD2_k127_1490691_3 Biopterin-dependent aromatic amino acid hydroxylase K00500 - 1.14.16.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007096 374.0
HFD2_k127_1490691_4 ABC transporter (Permease) K02033,K13894 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0022857,GO:0035672,GO:0042221,GO:0042493,GO:0042884,GO:0042886,GO:0042891,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944 - 0.00000007383 58.0
HFD2_k127_150775_1 Dehydrogenase K00114 - 1.1.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 567.0
HFD2_k127_150775_10 Class II aldolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008972 319.0
HFD2_k127_150775_11 cytochrome K17230 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005424 316.0
HFD2_k127_150775_12 Bacterial transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001723 258.0
HFD2_k127_150775_13 PFAM KWG Leptospira - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009332 256.0
HFD2_k127_150775_14 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005856 254.0
HFD2_k127_150775_15 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000002388 261.0
HFD2_k127_150775_16 4,5-dihydroxyphthalate decarboxylase K04102 - 4.1.1.55 0.000000000000000000000000000000000000000000000000000000000000004883 234.0
HFD2_k127_150775_17 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000006237 201.0
HFD2_k127_150775_18 Haem-degrading - - - 0.00000000000000000000000000000000000000000000000000001847 193.0
HFD2_k127_150775_19 Haem-degrading - - - 0.00000000000000000000000000000000000000000000000009948 184.0
HFD2_k127_150775_20 Ring hydroxylating beta subunit - - - 0.000000000000000000000000000000000000000000000000127 184.0
HFD2_k127_150775_21 Glyoxalase-like domain - - - 0.000000000000000000000000000000000004098 141.0
HFD2_k127_150775_23 Alpha/beta hydrolase family - - - 0.0000000000000000000000000009124 123.0
HFD2_k127_150775_24 nitrate reductase molybdenum cofactor assembly chaperone - - - 0.0000000000000000000000004376 109.0
HFD2_k127_150775_25 TPR repeat - - - 0.000000000000000000001488 102.0
HFD2_k127_150775_26 amine dehydrogenase activity - - - 0.000000000000000000008799 93.0
HFD2_k127_150775_27 Cupin domain - - - 0.00000000000000002493 87.0
HFD2_k127_150775_28 copper resistance protein K07156 - - 0.000003047 55.0
HFD2_k127_150775_29 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 0.00008464 55.0
HFD2_k127_150775_3 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 532.0
HFD2_k127_150775_30 - - - - 0.0001254 53.0
HFD2_k127_150775_31 Functions as an electron carrier between membrane-bound cytochrome b6-f and photosystem I in oxygenic photosynthesis K08906 - - 0.0003889 48.0
HFD2_k127_150775_4 Ring hydroxylating alpha subunit (catalytic domain) K10619 - 1.14.12.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 525.0
HFD2_k127_150775_5 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 522.0
HFD2_k127_150775_6 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 504.0
HFD2_k127_150775_7 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 461.0
HFD2_k127_150775_8 4,5-dihydroxyphthalate decarboxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 411.0
HFD2_k127_150775_9 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 394.0
HFD2_k127_1543719_0 DNA topological change - - - 1.632e-236 760.0
HFD2_k127_1543719_1 Glycosyl transferase family group 2 K03669 - - 4.328e-194 625.0
HFD2_k127_1543719_10 ankyrin repeat K15503 - - 0.000000000000000000000000000000000000000000000000001033 200.0
HFD2_k127_1543719_11 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000001171 162.0
HFD2_k127_1543719_12 - - - - 0.000000000000000000000000009366 122.0
HFD2_k127_1543719_13 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000002499 102.0
HFD2_k127_1543719_15 - - - - 0.0000000000000006797 89.0
HFD2_k127_1543719_16 COG2826 Transposase and inactivated derivatives, IS30 family - - - 0.00002868 47.0
HFD2_k127_1543719_2 DNA topological change K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 538.0
HFD2_k127_1543719_3 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006937 463.0
HFD2_k127_1543719_4 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006432 392.0
HFD2_k127_1543719_5 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 383.0
HFD2_k127_1543719_6 Protein of unknown function (DUF1552) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000696 343.0
HFD2_k127_1543719_7 protein-(glutamine-N5) methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000706 256.0
HFD2_k127_1543719_8 response to abiotic stimulus K06867 - - 0.000000000000000000000000000000000000000000000000000000000000002574 237.0
HFD2_k127_1543719_9 PepSY-associated TM region - - - 0.00000000000000000000000000000000000000000000000000000006772 211.0
HFD2_k127_156895_0 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003523 581.0
HFD2_k127_156895_1 Carbohydrate family 9 binding domain-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006153 568.0
HFD2_k127_156895_10 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002083 260.0
HFD2_k127_156895_11 Sel1 domain protein repeat-containing protein K07126 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001524 262.0
HFD2_k127_156895_12 MOSC domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002161 237.0
HFD2_k127_156895_13 NUDIX hydrolase - - - 0.0000000000000000000000000000000000000000000000000000003632 200.0
HFD2_k127_156895_14 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000004174 172.0
HFD2_k127_156895_15 - - - - 0.0000000000000000000000000000000000000002281 157.0
HFD2_k127_156895_16 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000009867 146.0
HFD2_k127_156895_17 - - - - 0.00000000000000000000000000004855 124.0
HFD2_k127_156895_18 - - - - 0.00000000000000000000000000008483 126.0
HFD2_k127_156895_19 - - - - 0.000000000000000000000003063 116.0
HFD2_k127_156895_2 Carbohydrate family 9 binding domain-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 535.0
HFD2_k127_156895_20 - - - - 0.000000000000000003572 95.0
HFD2_k127_156895_21 Putative esterase - - - 0.00000001376 65.0
HFD2_k127_156895_22 Restriction endonuclease K07448 - - 0.00000006728 58.0
HFD2_k127_156895_3 Carbohydrate family 9 binding domain-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 535.0
HFD2_k127_156895_4 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 496.0
HFD2_k127_156895_5 Cytochrome c class I K19713 - 1.8.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005735 364.0
HFD2_k127_156895_6 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 306.0
HFD2_k127_156895_7 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005688 296.0
HFD2_k127_156895_8 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003667 285.0
HFD2_k127_156895_9 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001796 274.0
HFD2_k127_1621151_0 Methionine synthase B12-binding module cap domain protein K00548,K15023 - 2.1.1.13,2.1.1.258 7.489e-265 826.0
HFD2_k127_1627210_0 Sigma-54 interaction domain - GO:0003674,GO:0003700,GO:0004857,GO:0006355,GO:0008073,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0010967,GO:0019219,GO:0019222,GO:0030234,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033238,GO:0042979,GO:0043086,GO:0044092,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 615.0
HFD2_k127_1627210_1 Pyruvate kinase, alpha/beta domain K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 582.0
HFD2_k127_1627210_10 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000000003226 75.0
HFD2_k127_1627210_11 addiction module antidote protein - - - 0.0000000000001795 71.0
HFD2_k127_1627210_2 NADP transhydrogenase subunit alpha K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005916 347.0
HFD2_k127_1627210_3 Lytic murein transglycosylase K08305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007792 306.0
HFD2_k127_1627210_4 PFAM N-formylglutamate amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004526 291.0
HFD2_k127_1627210_5 Uncharacterized protein conserved in bacteria (DUF2332) - - - 0.00000000000000000000000000000000000000000000000000003891 200.0
HFD2_k127_1627210_6 Protein conserved in bacteria K09948 - - 0.000000000000000000000000000000000779 144.0
HFD2_k127_1627210_7 Protein of unknown function (DUF1036) - - - 0.000000000000000000000000000003876 132.0
HFD2_k127_1627210_8 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000000000003088 127.0
HFD2_k127_1627210_9 Uncharacterized protein conserved in bacteria (DUF2312) - - - 0.000000000000000000000000009796 111.0
HFD2_k127_165458_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1413.0
HFD2_k127_165458_1 AcrB/AcrD/AcrF family - - - 0.0 1332.0
HFD2_k127_165458_10 Asparagine synthase K01953 - 6.3.5.4 0.0000001014 55.0
HFD2_k127_165458_11 Catalyzes the conversion of maleate to fumarate K01799 - 5.2.1.1 0.0000007692 60.0
HFD2_k127_165458_12 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000002842 59.0
HFD2_k127_165458_2 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004782 412.0
HFD2_k127_165458_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.000000000000000000000000000000000000000000000000000000000000802 217.0
HFD2_k127_165458_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000003728 152.0
HFD2_k127_165458_5 - - - - 0.00000000000000000000003983 110.0
HFD2_k127_165458_6 COG4257 Streptogramin lyase K18235 - - 0.00000000000000000001742 106.0
HFD2_k127_165458_7 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000001402 89.0
HFD2_k127_165458_8 Haem-degrading K11477 - - 0.00000000009342 69.0
HFD2_k127_165458_9 TIGRFAM TonB family protein K03832 - - 0.000000009835 67.0
HFD2_k127_1667699_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1193.0
HFD2_k127_1667699_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 1.102e-278 870.0
HFD2_k127_1667699_10 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 513.0
HFD2_k127_1667699_11 Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005102 464.0
HFD2_k127_1667699_12 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007452 462.0
HFD2_k127_1667699_13 Major Facilitator Superfamily K13021 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 417.0
HFD2_k127_1667699_14 Lactonase, 7-bladed beta-propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 407.0
HFD2_k127_1667699_15 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 375.0
HFD2_k127_1667699_16 TIGRFAM FeS assembly ATPase SufC K09013 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 377.0
HFD2_k127_1667699_17 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006029 312.0
HFD2_k127_1667699_18 diguanylate cyclase K07216,K13590 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005769 290.0
HFD2_k127_1667699_19 Uncharacterized protein family (UPF0051) K09015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002086 260.0
HFD2_k127_1667699_2 glutamine synthetase K01915 - 6.3.1.2 2.513e-234 734.0
HFD2_k127_1667699_20 signal transduction histidine kinase K07716 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000005908 258.0
HFD2_k127_1667699_21 nitrogen regulatory protein P-II K04751 GO:0003674,GO:0006808,GO:0008150,GO:0030234,GO:0050789,GO:0050790,GO:0065007,GO:0065009,GO:0098772 - 0.000000000000000000000000000000000000000000000000000001469 193.0
HFD2_k127_1667699_22 Iron-sulphur cluster biosynthesis K13628 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009058,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0018130,GO:0019438,GO:0019538,GO:0022607,GO:0031163,GO:0031974,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0051604,GO:0070013,GO:0071704,GO:0071840,GO:0097428,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000002427 179.0
HFD2_k127_1667699_23 NifU-like N terminal domain K04488 - - 0.00000000000000000000000000000000000000000000001156 178.0
HFD2_k127_1667699_24 Iron-sulfur cluster assembly protein - - - 0.00000000000000000000000000000000000000000006347 171.0
HFD2_k127_1667699_25 Glycosyl transferase family 41 - - - 0.00000000000000000000000000000000000000006421 166.0
HFD2_k127_1667699_26 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000000001643 120.0
HFD2_k127_1667699_27 EF hand - - - 0.00000000424 64.0
HFD2_k127_1667699_28 Ca2 -binding protein (EF-Hand superfamily - - - 0.0000002099 59.0
HFD2_k127_1667699_3 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 2.356e-229 715.0
HFD2_k127_1667699_4 FeS assembly protein SufB K09014 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009536,GO:0009842,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 - 1.858e-221 689.0
HFD2_k127_1667699_5 protein N-acetylglucosaminyltransferase activity - - - 2.88e-209 675.0
HFD2_k127_1667699_6 Glycosyl transferase family 41 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005981 626.0
HFD2_k127_1667699_7 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000808 537.0
HFD2_k127_1667699_8 Belongs to the DEAD box helicase family K03732,K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000055 541.0
HFD2_k127_1667699_9 Glycosyl transferase family 41 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 532.0
HFD2_k127_1670038_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007571 615.0
HFD2_k127_1670038_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 611.0
HFD2_k127_1670038_10 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 290.0
HFD2_k127_1670038_11 protein conserved in bacteria K09798 - - 0.0000000000000000000000000000000000000000000000000000000009711 214.0
HFD2_k127_1670038_12 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000003538 179.0
HFD2_k127_1670038_13 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000000000000000000000000004253 157.0
HFD2_k127_1670038_14 Peptidylprolyl isomerase K01802,K03770 - 5.2.1.8 0.00000000000000000000005142 108.0
HFD2_k127_1670038_2 AAA domain K07028 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008498 458.0
HFD2_k127_1670038_3 Domain of unknown function (DUF4131) K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005424 463.0
HFD2_k127_1670038_4 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005828 392.0
HFD2_k127_1670038_5 exodeoxyribonuclease III K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 393.0
HFD2_k127_1670038_6 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 361.0
HFD2_k127_1670038_7 Indole-3-glycerol phosphate synthase K01609,K13498 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48,5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006778 312.0
HFD2_k127_1670038_8 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 304.0
HFD2_k127_1670038_9 5'-3' exonuclease K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 316.0
HFD2_k127_1689109_0 Amidase K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 547.0
HFD2_k127_1689109_1 depolymerase K03932 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004034 248.0
HFD2_k127_1689109_10 lactoylglutathione lyase activity - - - 0.00002873 56.0
HFD2_k127_1689109_2 Bacterial extracellular solute-binding protein K02020 - - 0.0000000000000000000000000000000000000000000000000000000005371 211.0
HFD2_k127_1689109_3 COG0491 Zn-dependent hydrolases, including glyoxylases K17837 - 3.5.2.6 0.00000000000000000000000000000000000000173 159.0
HFD2_k127_1689109_4 Tellurite resistance protein TerB - - - 0.000000000000000000000000000000004574 133.0
HFD2_k127_1689109_5 - - - - 0.00000000000000000000000804 111.0
HFD2_k127_1689109_7 2OG-Fe(II) oxygenase superfamily - - - 0.00000000000000004 84.0
HFD2_k127_1689109_8 Domain of unknown function (DUF3859) - - - 0.000004661 55.0
HFD2_k127_1689109_9 lactoylglutathione lyase activity - - - 0.000006434 55.0
HFD2_k127_1702762_0 Serine aminopeptidase, S33 K01253,K08253 - 2.7.10.2,3.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007738 524.0
HFD2_k127_1702762_1 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004865 357.0
HFD2_k127_1702762_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005007 330.0
HFD2_k127_1702762_3 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007997 282.0
HFD2_k127_1702762_4 PFAM Mandelate racemase muconate lactonizing K01856,K02549,K19802,K21617,K21624 - 4.2.1.113,4.2.1.171,5.1.1.20,5.1.1.22,5.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000001434 254.0
HFD2_k127_1702762_5 Bacterial extracellular solute-binding protein - - - 0.00000000000000000000000000000000000000000000000000000707 208.0
HFD2_k127_1702762_6 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000002794 173.0
HFD2_k127_171487_0 DNA polymerase alpha chain like domain K02337 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.0 1268.0
HFD2_k127_171487_1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 3.434e-263 824.0
HFD2_k127_171487_10 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 370.0
HFD2_k127_171487_11 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005636 359.0
HFD2_k127_171487_12 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 347.0
HFD2_k127_171487_13 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 351.0
HFD2_k127_171487_14 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000996 348.0
HFD2_k127_171487_15 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 328.0
HFD2_k127_171487_16 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062 328.0
HFD2_k127_171487_17 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 306.0
HFD2_k127_171487_18 Udp N-acetylglucosamine O-acyltransferase; Domain 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 299.0
HFD2_k127_171487_19 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001458 282.0
HFD2_k127_171487_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 2.957e-250 796.0
HFD2_k127_171487_20 protein conserved in bacteria K09949 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003743 276.0
HFD2_k127_171487_21 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006931 266.0
HFD2_k127_171487_22 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004857 254.0
HFD2_k127_171487_23 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000009163 250.0
HFD2_k127_171487_24 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000004235 203.0
HFD2_k127_171487_25 EamA-like transporter family K15270 - - 0.00000000000000000000000000000000000000000000002477 182.0
HFD2_k127_171487_26 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000003887 175.0
HFD2_k127_171487_27 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000002549 160.0
HFD2_k127_171487_28 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000009841 106.0
HFD2_k127_171487_29 - - - - 0.0000000000000000000005493 104.0
HFD2_k127_171487_3 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 1.389e-220 690.0
HFD2_k127_171487_30 peptidase - - - 0.0000000000000000001167 92.0
HFD2_k127_171487_31 Protein of unknown function (DUF1467) - - - 0.00000000000000001497 85.0
HFD2_k127_171487_32 Outer membrane protein (OmpH-like) - - - 0.0000000000007126 79.0
HFD2_k127_171487_4 NADH ubiquinone oxidoreductase subunit 4 (chain M) K00342 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 2.714e-212 671.0
HFD2_k127_171487_5 Metallo-beta-lactamase superfamily K12574 - - 4.978e-207 657.0
HFD2_k127_171487_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009763 567.0
HFD2_k127_171487_7 lipoprotein releasing system, transmembrane protein, LolC E family' K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000858 492.0
HFD2_k127_171487_8 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 443.0
HFD2_k127_171487_9 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 434.0
HFD2_k127_1752769_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 4e-322 1002.0
HFD2_k127_1752769_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 4.765e-242 760.0
HFD2_k127_1752769_10 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162,K00627 - 1.2.4.1,2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003053 437.0
HFD2_k127_1752769_11 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 400.0
HFD2_k127_1752769_12 RibD C-terminal domain K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003845 349.0
HFD2_k127_1752769_13 Enoyl-CoA hydratase/isomerase K01692,K05605 - 3.1.2.4,4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005845 340.0
HFD2_k127_1752769_14 chemotaxis MotB protein K02557 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006745 335.0
HFD2_k127_1752769_15 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009504 331.0
HFD2_k127_1752769_16 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008443 310.0
HFD2_k127_1752769_17 riboflavin synthase alpha K00793 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000001336 261.0
HFD2_k127_1752769_18 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001112 244.0
HFD2_k127_1752769_19 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000586 229.0
HFD2_k127_1752769_2 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 1.384e-216 680.0
HFD2_k127_1752769_20 Belongs to the bacterioferritin family K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000009846 205.0
HFD2_k127_1752769_21 ROS/MUCR transcriptional regulator protein - - - 0.000000000000000000000000000000000000000000000000001488 186.0
HFD2_k127_1752769_22 Copper chaperone PCu(A)C K09796 - - 0.000000000000000000000000000000000000000000000000003017 194.0
HFD2_k127_1752769_23 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000001227 176.0
HFD2_k127_1752769_24 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000000000003479 164.0
HFD2_k127_1752769_25 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000001263 168.0
HFD2_k127_1752769_26 MerR HTH family regulatory protein - - - 0.00000000000000000000000000000000000000002948 157.0
HFD2_k127_1752769_27 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.00000000000000000000000000000000000001509 147.0
HFD2_k127_1752769_28 PFAM SmpA OmlA - - - 0.00000000000000000000000000002664 123.0
HFD2_k127_1752769_29 WHG domain - - - 0.0000000000000000000000000002801 123.0
HFD2_k127_1752769_3 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.1.2.1 1.041e-209 659.0
HFD2_k127_1752769_30 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000000000000000000001433 113.0
HFD2_k127_1752769_31 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000002903 98.0
HFD2_k127_1752769_32 Opacity family porin protein - - - 0.000000000000000000466 96.0
HFD2_k127_1752769_33 - - - - 0.00000003556 57.0
HFD2_k127_1752769_34 BFD domain protein 2Fe-2S -binding domain protein - - - 0.00008558 47.0
HFD2_k127_1752769_35 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0006078 51.0
HFD2_k127_1752769_4 Penicillin amidase K01434 - 3.5.1.11 5.926e-204 662.0
HFD2_k127_1752769_5 5-aminolevulinic acid synthase K00643 - 2.3.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 559.0
HFD2_k127_1752769_6 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 538.0
HFD2_k127_1752769_7 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858,K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004607 511.0
HFD2_k127_1752769_8 Belongs to the ALAD family K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 475.0
HFD2_k127_1752769_9 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000456 457.0
HFD2_k127_1761069_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2196.0
HFD2_k127_1761069_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046,K13797 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 1.639e-196 616.0
HFD2_k127_1761069_2 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 349.0
HFD2_k127_1761069_3 In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold. K02601 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008398 278.0
HFD2_k127_1761069_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000002262 229.0
HFD2_k127_1761069_5 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000001091 222.0
HFD2_k127_1761069_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000000000007243 182.0
HFD2_k127_1761069_7 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.00000000002129 67.0
HFD2_k127_1762775_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K15022 - 1.17.1.10 0.0 1010.0
HFD2_k127_1762775_1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 4.455e-298 925.0
HFD2_k127_1762775_10 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 304.0
HFD2_k127_1762775_11 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002349 273.0
HFD2_k127_1762775_12 phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001112 256.0
HFD2_k127_1762775_13 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000001143 200.0
HFD2_k127_1762775_14 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000000000000000002938 200.0
HFD2_k127_1762775_15 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000009869 149.0
HFD2_k127_1762775_16 - - - - 0.00000008391 59.0
HFD2_k127_1762775_2 2-methylcitrate dehydratase K01720 - 4.2.1.79 2.543e-251 782.0
HFD2_k127_1762775_3 Belongs to the citrate synthase family K01659 - 2.3.3.5 1.732e-200 630.0
HFD2_k127_1762775_4 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004222 566.0
HFD2_k127_1762775_5 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 461.0
HFD2_k127_1762775_6 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K03417 - 4.1.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 452.0
HFD2_k127_1762775_7 GtrA-like protein K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 448.0
HFD2_k127_1762775_8 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 424.0
HFD2_k127_1762775_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 334.0
HFD2_k127_1771055_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1052.0
HFD2_k127_1771055_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000008018 254.0
HFD2_k127_1771055_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000002007 212.0
HFD2_k127_1771055_3 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000001401 91.0
HFD2_k127_178509_0 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family - - - 3.08e-215 678.0
HFD2_k127_178509_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 416.0
HFD2_k127_178509_2 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009531 367.0
HFD2_k127_178509_3 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 329.0
HFD2_k127_178509_4 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000004012 165.0
HFD2_k127_178509_5 Transcriptional regulator - - - 0.000000000000000000000000000001842 126.0
HFD2_k127_178771_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 529.0
HFD2_k127_178771_1 argininosuccinate lyase K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006758 479.0
HFD2_k127_178771_10 Phosphoribosyl transferase domain K00760 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.8 0.00000000000000000000004784 106.0
HFD2_k127_178771_11 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000004298 87.0
HFD2_k127_178771_2 Domain of unknown function (DUF4175) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 439.0
HFD2_k127_178771_3 ATPases associated with a variety of cellular activities K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 323.0
HFD2_k127_178771_4 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000006603 238.0
HFD2_k127_178771_5 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000001995 203.0
HFD2_k127_178771_6 Cell division protein K09811 - - 0.0000000000000000000000000000000000000000000001112 186.0
HFD2_k127_178771_7 zinc-ribbon domain - - - 0.000000000000000000000000000000000000000001555 167.0
HFD2_k127_178771_8 DUF218 domain - - - 0.0000000000000000000000000000000000000177 151.0
HFD2_k127_178771_9 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.000000000000000000000000004636 112.0
HFD2_k127_179485_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 2.057e-288 901.0
HFD2_k127_179485_1 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K21105 - 3.1.1.102 1.338e-205 654.0
HFD2_k127_179485_2 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 293.0
HFD2_k127_179485_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000006012 223.0
HFD2_k127_179485_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000007279 213.0
HFD2_k127_179485_5 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000006067 207.0
HFD2_k127_179485_6 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00124,K07307 - - 0.00000000000000000000000000000000000001303 151.0
HFD2_k127_179485_7 branched-chain amino acid transmembrane transporter activity K01996 - - 0.00000000000000000000000000000000000113 144.0
HFD2_k127_1802929_0 PFAM response regulator receiver K02282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 327.0
HFD2_k127_1802929_1 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.0000000000004681 79.0
HFD2_k127_1802929_2 Type II/IV secretion system protein K02283 - - 0.000001381 54.0
HFD2_k127_1812158_0 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001486 256.0
HFD2_k127_1812158_1 Hydantoin racemase K16841 - 5.1.99.3 0.0000000000000335 82.0
HFD2_k127_185179_0 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K21105 - 3.1.1.102 7.15e-209 664.0
HFD2_k127_185179_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007107 314.0
HFD2_k127_185179_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00124,K07307 - - 0.00000000000000000000000000000000000000005542 158.0
HFD2_k127_1855684_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.000000000000000000000000000000000000000000000000000000526 194.0
HFD2_k127_1855684_1 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000000000003148 172.0
HFD2_k127_1855684_2 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.0000000000000000000000000000000000000000000002223 177.0
HFD2_k127_1855684_3 transcriptional regulator K18301,K19736 - - 0.000000000000000000000000000000000000001811 154.0
HFD2_k127_1855684_4 Nickel/cobalt transporter regulator - - - 0.00002304 55.0
HFD2_k127_185849_0 Adenylate - - - 1.428e-291 936.0
HFD2_k127_185849_1 peroxidase K07223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 486.0
HFD2_k127_185849_2 Cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000003128 194.0
HFD2_k127_185849_3 Opioid growth factor receptor (OGFr) conserved region - - - 0.00000000000000000000000000000000000000000769 162.0
HFD2_k127_185849_4 Protein of unknown function (DUF1153) - - - 0.00000000000000000000000000000001227 132.0
HFD2_k127_185849_5 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000001551 112.0
HFD2_k127_1861761_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01576,K01652 - 2.2.1.6,4.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 595.0
HFD2_k127_1861761_1 Belongs to the NiCoT transporter (TC 2.A.52) family K07241 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006114 458.0
HFD2_k127_1861761_10 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000002251 83.0
HFD2_k127_1861761_11 Bacterial antitoxin of type II TA system, VapB - - - 0.00000000000001661 79.0
HFD2_k127_1861761_12 Cytochrome c K17760 - 1.1.9.1 0.00005102 52.0
HFD2_k127_1861761_2 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 356.0
HFD2_k127_1861761_3 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 325.0
HFD2_k127_1861761_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000006207 237.0
HFD2_k127_1861761_5 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01576,K01652 - 2.2.1.6,4.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000003884 237.0
HFD2_k127_1861761_6 transcriptional regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000001182 216.0
HFD2_k127_1861761_7 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000006141 156.0
HFD2_k127_1861761_8 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.0000000000000000000000000000000006207 136.0
HFD2_k127_1861761_9 Antidote-toxin recognition MazE, bacterial antitoxin K18829 - - 0.00000000000000000000000003923 114.0
HFD2_k127_1884558_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003627 527.0
HFD2_k127_1884558_1 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000003154 168.0
HFD2_k127_1938122_0 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 466.0
HFD2_k127_1938122_1 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 436.0
HFD2_k127_1938122_10 Ribosomal RNA adenine dimethylase K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000001025 199.0
HFD2_k127_1938122_11 - - - - 0.00000000000000000000000000000000000000000000000001145 192.0
HFD2_k127_1938122_12 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.000000000000000000000000000000000000000000005186 176.0
HFD2_k127_1938122_13 Gluconate 2-dehydrogenase K06152 - 1.1.99.3 0.00000000000000000000000002038 117.0
HFD2_k127_1938122_14 - - - - 0.000000000000000000000001131 114.0
HFD2_k127_1938122_15 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate - - - 0.00000000000000000000003536 111.0
HFD2_k127_1938122_16 - - - - 0.0000000000000000000001107 104.0
HFD2_k127_1938122_17 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000007468 57.0
HFD2_k127_1938122_18 Cytochrome C oxidase, cbb3-type, subunit III K03889 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000009544 57.0
HFD2_k127_1938122_19 Domain of unknown function (DUF5122) beta-propeller - - - 0.00002264 59.0
HFD2_k127_1938122_2 pathogenesis K13735,K20276,K21449 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006217 432.0
HFD2_k127_1938122_3 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009564 394.0
HFD2_k127_1938122_4 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 364.0
HFD2_k127_1938122_5 Oxidoreductase molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 316.0
HFD2_k127_1938122_6 PFAM Acetamidase Formamidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 336.0
HFD2_k127_1938122_7 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004059 289.0
HFD2_k127_1938122_8 Caspase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008265 275.0
HFD2_k127_1938122_9 Outer membrane efflux protein K12340 - - 0.0000000000000000000000000000000000000000000000000000000000001498 223.0
HFD2_k127_1948441_0 (E1) component, eukaryotic type, alpha subunit K21416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003844 257.0
HFD2_k127_1948441_1 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K00162,K21417 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000007827 242.0
HFD2_k127_1948441_2 helix_turn_helix, Lux Regulon K02479 - - 0.00000000000000000000000000000001723 132.0
HFD2_k127_1954918_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 3.527e-257 809.0
HFD2_k127_1954918_1 D-galactarate dehydratase Altronate hydrolase K16846,K16850 - 4.2.1.7,4.4.1.24 1.083e-217 685.0
HFD2_k127_1954918_10 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007072 302.0
HFD2_k127_1954918_11 hydrolases or acyltransferases (alpha beta hydrolase superfamily) K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001091 291.0
HFD2_k127_1954918_12 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001488 279.0
HFD2_k127_1954918_13 Transglycosylase K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000000000003559 243.0
HFD2_k127_1954918_14 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.00000000000000000000000000000000000000000000000000000000000000000007762 237.0
HFD2_k127_1954918_15 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.0000000000000000000000000000000000000000000000000000000002059 210.0
HFD2_k127_1954918_16 PFAM Glutathione S-transferase domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000001102 183.0
HFD2_k127_1954918_17 SAF K16845 - 4.4.1.24 0.000000000000000000000000000000000000000000000004761 175.0
HFD2_k127_1954918_18 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000001188 163.0
HFD2_k127_1954918_19 Belongs to the small heat shock protein (HSP20) family - - - 0.00000000000000000000000000000000000003575 151.0
HFD2_k127_1954918_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 552.0
HFD2_k127_1954918_20 - - - - 0.0000000000000000000000000000000000007337 152.0
HFD2_k127_1954918_21 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - 0.000000000000000000000000001134 117.0
HFD2_k127_1954918_22 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.00000000000000000001086 100.0
HFD2_k127_1954918_23 Cytochrome c - - - 0.00000000000000000001154 95.0
HFD2_k127_1954918_24 - - - - 0.0000000000000000109 85.0
HFD2_k127_1954918_25 OstA-like protein K09774 - - 0.000000002566 68.0
HFD2_k127_1954918_26 COG3278 Cbb3-type cytochrome oxidase, subunit 1 - - - 0.000000004019 64.0
HFD2_k127_1954918_27 Acetyltransferase (GNAT) domain - - - 0.000000007146 64.0
HFD2_k127_1954918_29 Belongs to the heme-copper respiratory oxidase family - - - 0.000001079 55.0
HFD2_k127_1954918_3 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 494.0
HFD2_k127_1954918_30 Protein of unknown function (DUF1150) - - - 0.00001857 51.0
HFD2_k127_1954918_4 Belongs to the LDH2 MDH2 oxidoreductase family K16844 - 1.1.1.338 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006794 405.0
HFD2_k127_1954918_5 ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 374.0
HFD2_k127_1954918_6 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007191 371.0
HFD2_k127_1954918_7 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000707 366.0
HFD2_k127_1954918_8 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 342.0
HFD2_k127_1954918_9 3'-5' exonuclease K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007057 302.0
HFD2_k127_1967067_0 Mo-co oxidoreductase dimerisation domain K17225 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006777 424.0
HFD2_k127_1967067_1 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000002981 236.0
HFD2_k127_1967067_2 Cytochrome C oxidase, cbb3-type, subunit III K08738 - - 0.000000000000000000000000000000000000000000000000000004546 195.0
HFD2_k127_204270_0 Glycosyl transferase family 21 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003993 443.0
HFD2_k127_204270_1 NmrA-like family K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000311 437.0
HFD2_k127_204270_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 359.0
HFD2_k127_204270_3 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 316.0
HFD2_k127_204270_4 Squalene/phytoene synthase K21679 - 4.2.3.156 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 331.0
HFD2_k127_204270_5 Methyltransferase FkbM domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009277 267.0
HFD2_k127_204270_6 Belongs to the MIP aquaporin (TC 1.A.8) family - - - 0.00000000000000000000000000000000000000000000000000000000000000001716 238.0
HFD2_k127_204270_7 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.00000000000000000000000000000000000000000000000000000000000000006654 228.0
HFD2_k127_204270_8 transcriptional regulators K03892 - - 0.0000000000000000000000000000000003683 135.0
HFD2_k127_204270_9 spectrin binding - - - 0.00005876 49.0
HFD2_k127_2045932_0 Belongs to the argininosuccinate synthase family. Type 2 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 4.327e-227 707.0
HFD2_k127_2045932_1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000000000000000000000000000000000000000000000000005612 232.0
HFD2_k127_2045932_2 Transcriptional regulator - - - 0.0000000000000000000000000000000119 129.0
HFD2_k127_2045932_3 addiction module killer protein - - - 0.00000000000000000000000000000008318 126.0
HFD2_k127_2045932_4 Tetratricopeptide repeat - - - 0.0000000000000000003437 97.0
HFD2_k127_2067516_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 1.571e-217 693.0
HFD2_k127_2067516_1 Phosphoglucose isomerase K01810 - 5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 377.0
HFD2_k127_2067516_2 Acetamidase/Formamidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 308.0
HFD2_k127_2067516_3 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000002395 211.0
HFD2_k127_2067516_5 Conserved hypothetical protein 698 - - - 0.00000008929 53.0
HFD2_k127_2067516_6 General function prediction only K11477 - - 0.000000244 60.0
HFD2_k127_2095222_0 sister chromatid segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005238 519.0
HFD2_k127_2095222_1 - - - - 0.0000000000000000000000001056 109.0
HFD2_k127_2107003_0 Bacterial NAD-glutamate dehydrogenase K15371 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0008150,GO:0008152,GO:0016491,GO:0016638,GO:0016639,GO:0055114 1.4.1.2 0.0 1365.0
HFD2_k127_2107003_1 COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes K00164 - 1.2.4.2 0.0 1309.0
HFD2_k127_2107003_10 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003969 463.0
HFD2_k127_2107003_11 Glycoprotease family K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360,GO:1901564 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003214 421.0
HFD2_k127_2107003_12 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005861 397.0
HFD2_k127_2107003_13 Acetoacetyl-CoA reductase K00023 - 1.1.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 362.0
HFD2_k127_2107003_14 exodeoxyribonuclease III K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 352.0
HFD2_k127_2107003_15 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004819 320.0
HFD2_k127_2107003_16 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 306.0
HFD2_k127_2107003_17 Adenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007666 318.0
HFD2_k127_2107003_18 CYTH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 315.0
HFD2_k127_2107003_19 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 299.0
HFD2_k127_2107003_2 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 0.0 1242.0
HFD2_k127_2107003_20 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004202 286.0
HFD2_k127_2107003_21 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000000000000000000000000000000000000000000000000000002067 230.0
HFD2_k127_2107003_22 PHB accumulation regulatory domain - - - 0.00000000000000000000000000000000000000000000000000000000000001463 221.0
HFD2_k127_2107003_23 Cupin superfamily K09705 - - 0.000000000000000000000000000000000000000000000000000000153 199.0
HFD2_k127_2107003_24 probably involved in intracellular septation K06190 - - 0.000000000000000000000000000000000000000000000000000002214 197.0
HFD2_k127_2107003_25 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000005482 191.0
HFD2_k127_2107003_26 Protein of unknown function (DUF1223) - - - 0.00000000000000000000000000000000000000000000000001248 192.0
HFD2_k127_2107003_27 COG1587 Uroporphyrinogen-III synthase K01719 - 4.2.1.75 0.000000000000000000000000000000000000000000000009946 179.0
HFD2_k127_2107003_28 Thiol disulfide interchange protein K02199 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000000000000000000000000000000000001466 180.0
HFD2_k127_2107003_29 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000001451 172.0
HFD2_k127_2107003_3 peptidase S9A prolyl oligopeptidase domain protein beta-propeller K01322 - 3.4.21.26 7.106e-204 656.0
HFD2_k127_2107003_30 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000001211 163.0
HFD2_k127_2107003_31 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000003217 132.0
HFD2_k127_2107003_32 Exonuclease - - - 0.00000000000000000000000402 112.0
HFD2_k127_2107003_33 Plasmid stabilization system K19092 - - 0.00000000000001656 77.0
HFD2_k127_2107003_34 Protein of unknown function (DUF992) - - - 0.00000000003477 64.0
HFD2_k127_2107003_35 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.00002135 48.0
HFD2_k127_2107003_4 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 GO:0000166,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009507,GO:0009536,GO:0010035,GO:0010038,GO:0016020,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0017076,GO:0019866,GO:0030554,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045271,GO:0046686,GO:0046872,GO:0046914,GO:0048046,GO:0050896,GO:0050897,GO:0055114,GO:0070469,GO:0097159,GO:0097367,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 611.0
HFD2_k127_2107003_5 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 592.0
HFD2_k127_2107003_6 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005406 583.0
HFD2_k127_2107003_7 MiaB-like tRNA modifying enzyme K18707 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 524.0
HFD2_k127_2107003_8 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 497.0
HFD2_k127_2107003_9 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 497.0
HFD2_k127_212618_0 Methyltransferase small domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006369 384.0
HFD2_k127_212618_1 DNA restriction-modification system - - - 0.000000000000000000000000000000006495 149.0
HFD2_k127_212618_2 methylase - - - 0.0000000006182 74.0
HFD2_k127_2144298_0 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000003113 263.0
HFD2_k127_2144298_1 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K00162,K21417 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000003165 250.0
HFD2_k127_2144298_2 - - - - 0.00000002248 56.0
HFD2_k127_2217214_0 similarity to GP 17427840 K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 404.0
HFD2_k127_2217214_1 - - - - 0.00004626 46.0
HFD2_k127_2233136_0 MMPL family - - - 2.628e-228 740.0
HFD2_k127_2233136_1 Dehydrogenase K00117 - 1.1.5.2 4.509e-199 640.0
HFD2_k127_2233136_10 Belongs to the beta-ketoacyl-ACP synthases family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008255 406.0
HFD2_k127_2233136_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 399.0
HFD2_k127_2233136_12 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004673 395.0
HFD2_k127_2233136_13 Glycosyl transferase family 2 K00786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 367.0
HFD2_k127_2233136_14 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 353.0
HFD2_k127_2233136_15 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 332.0
HFD2_k127_2233136_16 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 331.0
HFD2_k127_2233136_17 cytochrome - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 333.0
HFD2_k127_2233136_18 Beta-lactamase superfamily domain K06167 - 3.1.4.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005411 324.0
HFD2_k127_2233136_19 Oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009155 324.0
HFD2_k127_2233136_2 Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 590.0
HFD2_k127_2233136_20 Bacterial lipid A biosynthesis acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007533 308.0
HFD2_k127_2233136_21 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 301.0
HFD2_k127_2233136_22 Transcriptional regulatory protein, C terminal K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003357 275.0
HFD2_k127_2233136_23 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007088 282.0
HFD2_k127_2233136_24 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006837 255.0
HFD2_k127_2233136_25 Beta-ketoacyl synthase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008295 254.0
HFD2_k127_2233136_26 Oxidoreductase molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006124 256.0
HFD2_k127_2233136_27 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002578 252.0
HFD2_k127_2233136_28 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000005334 245.0
HFD2_k127_2233136_29 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000005744 233.0
HFD2_k127_2233136_3 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004852 593.0
HFD2_k127_2233136_30 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000000000000000000000000000000000000007517 239.0
HFD2_k127_2233136_31 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000004242 227.0
HFD2_k127_2233136_32 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000007615 225.0
HFD2_k127_2233136_33 Thiosulfate reductase cytochrome B subunit (Membrane anchoring - - - 0.000000000000000000000000000000000000000000000000000000000000001012 230.0
HFD2_k127_2233136_34 Nodulation protein S (NodS) - - - 0.000000000000000000000000000000000000000000000000000000000000005937 222.0
HFD2_k127_2233136_35 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000000000000000000000004162 183.0
HFD2_k127_2233136_36 dehydratase - - - 0.000000000000000000000000000000000000000001965 161.0
HFD2_k127_2233136_37 DsrE/DsrF-like family - - - 0.000000000000000000000000000000000000000004072 158.0
HFD2_k127_2233136_38 OsmC-like protein K06889,K07397 - - 0.0000000000000000000000000000000000002097 147.0
HFD2_k127_2233136_39 - - - - 0.00000000000000000000000000000000001141 143.0
HFD2_k127_2233136_4 fad dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 558.0
HFD2_k127_2233136_40 Amidohydrolase K03392 - 4.1.1.45 0.000000000000000000000000000000489 134.0
HFD2_k127_2233136_41 Phosphopantetheine attachment site K02078 - - 0.00000000000000000000000000003457 121.0
HFD2_k127_2233136_42 Domain of unkown function (DUF1775) - - - 0.00000000000000000000000000003485 123.0
HFD2_k127_2233136_43 membrane - - - 0.0000000000000000000000000004939 121.0
HFD2_k127_2233136_45 - - - - 0.000000000000000000000000001457 123.0
HFD2_k127_2233136_46 - - - - 0.00000000000000000000001793 111.0
HFD2_k127_2233136_47 - - - - 0.00000000000000000000004508 110.0
HFD2_k127_2233136_48 - - - - 0.000000000000000000000368 102.0
HFD2_k127_2233136_49 FabA-like domain - - - 0.00000000000000000006869 92.0
HFD2_k127_2233136_5 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006215 565.0
HFD2_k127_2233136_50 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.0000000000000000001648 89.0
HFD2_k127_2233136_51 - - - - 0.0000000000000000345 91.0
HFD2_k127_2233136_52 Cupin 2, conserved barrel domain protein - - - 0.0000000000000001003 88.0
HFD2_k127_2233136_53 - - - - 0.00000000001513 71.0
HFD2_k127_2233136_54 - - - - 0.000000001619 63.0
HFD2_k127_2233136_55 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000004568 66.0
HFD2_k127_2233136_56 Haem-degrading K11477 - - 0.00000001049 66.0
HFD2_k127_2233136_57 - - - - 0.00000004942 59.0
HFD2_k127_2233136_6 Beta-ketoacyl synthase, C-terminal domain K00647,K09458 - 2.3.1.179,2.3.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002661 508.0
HFD2_k127_2233136_7 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008971 485.0
HFD2_k127_2233136_8 HpcH/HpaI aldolase/citrate lyase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 436.0
HFD2_k127_2233136_9 AMP-binding enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008255 436.0
HFD2_k127_2308431_0 GMC oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 475.0
HFD2_k127_2308431_1 - - - - 0.000000000000000000000000000000000000000008474 161.0
HFD2_k127_2308431_2 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 0.000000000000000000000000000000000007913 140.0
HFD2_k127_232433_0 Dehydrogenase E1 component K00161 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009573 470.0
HFD2_k127_2353905_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 0.0 1295.0
HFD2_k127_2353905_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 3.798e-244 775.0
HFD2_k127_2353905_10 Prolyl 4-hydroxylase alpha subunit homologues. K00472 - 1.14.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009221 277.0
HFD2_k127_2353905_11 Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length K01716 - 4.2.1.59,5.3.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000003762 259.0
HFD2_k127_2353905_12 Prolyl 4-hydroxylase alpha subunit homologues. K00472 - 1.14.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000009904 250.0
HFD2_k127_2353905_13 GrpB protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000038 231.0
HFD2_k127_2353905_14 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000001912 225.0
HFD2_k127_2353905_15 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS - - - 0.000000000000000000000000000000000000000000000000000000002175 204.0
HFD2_k127_2353905_16 Bacterial transcriptional repressor C-terminal - - - 0.000000000000000000000000000000000000000000000000000001663 199.0
HFD2_k127_2353905_17 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000001926 204.0
HFD2_k127_2353905_18 Belongs to the Fur family K09826 - - 0.00000000000000000000000000000000000000000000000002225 182.0
HFD2_k127_2353905_19 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.00000000000000000000000000000000000000000000002683 182.0
HFD2_k127_2353905_2 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 4.926e-218 691.0
HFD2_k127_2353905_20 COG0845 Membrane-fusion protein K01993 - - 0.0000000000000000000000000000000000000000000001151 183.0
HFD2_k127_2353905_21 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000001536 158.0
HFD2_k127_2353905_22 - - - - 0.00000000000000000000002616 107.0
HFD2_k127_2353905_23 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000000000000001879 85.0
HFD2_k127_2353905_24 Cysteine-rich domain K00113 - 1.1.5.3 0.000000003182 58.0
HFD2_k127_2353905_26 - - - - 0.000002502 54.0
HFD2_k127_2353905_27 Glycosyltransferase family 25 (LPS biosynthesis protein) - - - 0.00001587 55.0
HFD2_k127_2353905_3 Beta-ketoacyl synthase, C-terminal domain K00647 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.41 1.712e-199 628.0
HFD2_k127_2353905_4 Transport of potassium into the cell - - - 5.593e-197 634.0
HFD2_k127_2353905_5 FMN_bind K19339,K19343 - - 4.262e-194 642.0
HFD2_k127_2353905_6 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 486.0
HFD2_k127_2353905_7 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008519 431.0
HFD2_k127_2353905_8 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 428.0
HFD2_k127_2353905_9 Enoyl-(Acyl carrier protein) reductase K00208 GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901576 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009513 406.0
HFD2_k127_2416552_0 acyl-CoA dehydrogenase K06445 - - 3.4e-232 730.0
HFD2_k127_2416552_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01576,K01652 - 2.2.1.6,4.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 619.0
HFD2_k127_2416552_2 - - - - 0.0000000000000000000000000000000000000000000000000000001401 203.0
HFD2_k127_2416552_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000001657 83.0
HFD2_k127_2416552_4 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.0000000000000001981 92.0
HFD2_k127_2432451_0 E1-E2 ATPase K01535 - 3.6.3.6 1.599e-301 945.0
HFD2_k127_2432451_1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 5.435e-268 840.0
HFD2_k127_2432451_10 Universal stress protein family - - - 0.0000000000000000000000000000000000001782 147.0
HFD2_k127_2432451_11 Phenylacetic acid - - - 0.00000000000000001122 92.0
HFD2_k127_2432451_12 Bacterial extracellular solute-binding protein - - - 0.000001271 57.0
HFD2_k127_2432451_2 Belongs to the UbiD family K03182 - 4.1.1.98 3.221e-253 789.0
HFD2_k127_2432451_3 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 492.0
HFD2_k127_2432451_4 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004305 467.0
HFD2_k127_2432451_5 Major Facilitator Superfamily K13021 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 442.0
HFD2_k127_2432451_6 PFAM Enoyl-CoA hydratase isomerase K16880 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000927 413.0
HFD2_k127_2432451_7 ornithine cyclodeaminase K01750 - 4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000004854 236.0
HFD2_k127_2432451_8 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000001232 230.0
HFD2_k127_2432451_9 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000008098 218.0
HFD2_k127_2432676_0 PAS domain K00575,K13924 - 2.1.1.80,3.1.1.61 5.514e-302 956.0
HFD2_k127_2432676_1 ABC-type antimicrobial peptide transport system, permease component K02004 - - 1.791e-243 778.0
HFD2_k127_2432676_10 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 285.0
HFD2_k127_2432676_11 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009922 289.0
HFD2_k127_2432676_12 Protein of unknown function (DUF1345) - - - 0.000000000000000000000000000000000000000000000001776 181.0
HFD2_k127_2432676_13 Isochorismatase family - - - 0.000000000000000000000000000000000000003941 154.0
HFD2_k127_2432676_14 Multiubiquitin - - - 0.0000000000000000000000000000000001276 134.0
HFD2_k127_2432676_15 Transglycosylase associated protein - - - 0.000000000000000000000000000001886 123.0
HFD2_k127_2432676_16 Zinc-finger domain - - - 0.000000000000000000000005006 105.0
HFD2_k127_2432676_18 - - - - 0.000000000000000000009067 98.0
HFD2_k127_2432676_19 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000003022 92.0
HFD2_k127_2432676_2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01576,K01652 - 2.2.1.6,4.1.1.7 3.575e-223 710.0
HFD2_k127_2432676_20 CsbD-like - - - 0.0000000000000000003199 90.0
HFD2_k127_2432676_21 - - - - 0.000000000000000001629 89.0
HFD2_k127_2432676_22 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000007002 79.0
HFD2_k127_2432676_23 - - - - 0.0000000000007177 75.0
HFD2_k127_2432676_24 - - - - 0.000000000003297 74.0
HFD2_k127_2432676_25 GYD domain - - - 0.0000000005444 63.0
HFD2_k127_2432676_26 Catalyzes the NAD( )-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non- methylotrophic organisms K00122 - 1.17.1.9 0.000000004353 59.0
HFD2_k127_2432676_27 GYD domain - - - 0.0000001002 54.0
HFD2_k127_2432676_28 GYD domain - - - 0.0000003609 56.0
HFD2_k127_2432676_29 - - - - 0.0002741 50.0
HFD2_k127_2432676_3 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 612.0
HFD2_k127_2432676_4 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000488 485.0
HFD2_k127_2432676_5 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009726 477.0
HFD2_k127_2432676_6 Lipocalin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006013 459.0
HFD2_k127_2432676_7 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 437.0
HFD2_k127_2432676_8 PFAM major facilitator superfamily MFS_1 K13021 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 374.0
HFD2_k127_2432676_9 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 324.0
HFD2_k127_243686_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 GO:0008150,GO:0008152,GO:0055114 1.6.1.2 3.143e-227 712.0
HFD2_k127_243686_1 TIGRFAM methylmalonic acid semialdehyde dehydrogenase K00140 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006950,GO:0006979,GO:0008150,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050896 1.2.1.18,1.2.1.27 7.465e-222 694.0
HFD2_k127_243686_2 - - - - 0.000000000000000000000000000000000000000000000001608 176.0
HFD2_k127_243686_3 NAD(P) transhydrogenase, alpha subunit K00324 GO:0000166,GO:0003674,GO:0003824,GO:0003957,GO:0005215,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006740,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0008746,GO:0008750,GO:0009117,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0016491,GO:0016651,GO:0016652,GO:0019362,GO:0019637,GO:0022857,GO:0022890,GO:0034220,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046496,GO:0046983,GO:0048037,GO:0050662,GO:0051179,GO:0051186,GO:0051234,GO:0051287,GO:0055085,GO:0055086,GO:0055114,GO:0070403,GO:0070404,GO:0071704,GO:0072524,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1902600 1.6.1.2 0.00000000000000000000000000000000000000000000003088 171.0
HFD2_k127_243686_4 NAD NADP transhydrogenase alpha subunit K00324 GO:0008150,GO:0008152,GO:0055114 1.6.1.2 0.00000000000000000000000000000000000001817 152.0
HFD2_k127_2523446_0 metal-dependent hydrolase with the TIM-barrel fold - - - 5.559e-256 801.0
HFD2_k127_2523446_1 Sugar (and other) transporter K03446 - - 1.202e-207 657.0
HFD2_k127_2523446_10 Catalyzes the conversion of maleate to fumarate K01799 - 5.2.1.1 0.0000000007527 69.0
HFD2_k127_2523446_11 - - - - 0.0000000761 63.0
HFD2_k127_2523446_12 GIY-YIG catalytic domain - - - 0.000007835 51.0
HFD2_k127_2523446_2 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 599.0
HFD2_k127_2523446_3 PQQ-like domain K00114,K20937 - 1.1.2.8,1.1.5.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 514.0
HFD2_k127_2523446_4 HlyD family secretion protein K03543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007212 361.0
HFD2_k127_2523446_5 YCII-related domain - - - 0.000000000000000000000000000000000000000000000000000002479 192.0
HFD2_k127_2523446_6 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000006837 143.0
HFD2_k127_2523446_7 - - - - 0.00000000000000000000005511 110.0
HFD2_k127_2523446_8 - - - - 0.0000000000000000000007853 106.0
HFD2_k127_2523446_9 carboxymethylenebutenolidase activity K01061,K06889 - 3.1.1.45 0.0000000000000005769 87.0
HFD2_k127_2533808_0 helicase K03722 - 3.6.4.12 1.709e-276 880.0
HFD2_k127_2533808_1 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 6.529e-219 691.0
HFD2_k127_2533808_10 Protein of unknown function (DUF971) - - - 0.0000000000000000000000000000000000000000752 155.0
HFD2_k127_2533808_11 Aminoacyl-tRNA editing domain K19055 - - 0.00000000000000000000000000000000000000181 150.0
HFD2_k127_2533808_12 Protein of unknown function (DUF952) - - - 0.000000000000000000000000000000009548 132.0
HFD2_k127_2533808_13 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000004016 123.0
HFD2_k127_2533808_14 Phage P22-like portal protein - - - 0.000000000000000000000001377 103.0
HFD2_k127_2533808_15 Trm112p-like protein K09791 - - 0.000000000000000000000007816 101.0
HFD2_k127_2533808_16 Tetratricopeptide repeat - - - 0.00000000000000000003806 100.0
HFD2_k127_2533808_17 - - - - 0.00000000000001968 78.0
HFD2_k127_2533808_18 - - - - 0.00005057 48.0
HFD2_k127_2533808_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 516.0
HFD2_k127_2533808_3 2'-deoxycytidine 5'-triphosphate deaminase (DCD) K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 491.0
HFD2_k127_2533808_4 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases K13049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006551 444.0
HFD2_k127_2533808_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007662 343.0
HFD2_k127_2533808_6 Tetratricopeptide repeat K03671,K05838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007328 335.0
HFD2_k127_2533808_7 Bacterial extracellular solute-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000627 289.0
HFD2_k127_2533808_8 to the N-terminal domain of Lon protease K01338,K07157 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000007763 220.0
HFD2_k127_2533808_9 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000003495 191.0
HFD2_k127_2540999_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 487.0
HFD2_k127_2540999_1 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000002033 224.0
HFD2_k127_2540999_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000392 210.0
HFD2_k127_2540999_3 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000003721 87.0
HFD2_k127_2540999_5 - - - - 0.00008529 48.0
HFD2_k127_2550978_0 AcrB/AcrD/AcrF family K03296,K07788,K07789,K21133 - - 0.0 1054.0
HFD2_k127_2550978_1 elongation factor G K02355 - - 5.647e-243 771.0
HFD2_k127_2550978_10 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 458.0
HFD2_k127_2550978_11 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 411.0
HFD2_k127_2550978_12 C-terminal domain of 1-Cys peroxiredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 398.0
HFD2_k127_2550978_13 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 402.0
HFD2_k127_2550978_14 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002931 402.0
HFD2_k127_2550978_15 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483,K13584 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 350.0
HFD2_k127_2550978_16 Di-haem oxidoreductase, putative peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000322 351.0
HFD2_k127_2550978_17 Fumarylacetoacetate (FAA) hydrolase family K16165 - 3.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 317.0
HFD2_k127_2550978_18 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483,K13584 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005627 312.0
HFD2_k127_2550978_19 L,D-transpeptidase catalytic domain K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005845 314.0
HFD2_k127_2550978_2 Aldehyde oxidase and xanthine dehydrogenase K00256 - 1.3.99.16 5.182e-224 722.0
HFD2_k127_2550978_20 PAS fold - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004407 300.0
HFD2_k127_2550978_21 Glutathione S-transferase, N-terminal domain K01800,K01801,K03599 - 5.2.1.2,5.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000003235 258.0
HFD2_k127_2550978_22 Biotin-lipoyl like K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000003887 252.0
HFD2_k127_2550978_23 Transcriptional - GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006355,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009889,GO:0009987,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0016054,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0042221,GO:0043200,GO:0043201,GO:0043436,GO:0043565,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901698,GO:1901700,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000003479 222.0
HFD2_k127_2550978_24 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000002217 224.0
HFD2_k127_2550978_25 Imelysin K07338 - - 0.0000000000000000000000000000000000000000000000000000000000112 220.0
HFD2_k127_2550978_26 PFAM 2Fe-2S -binding domain-containing protein K18029 - 1.17.2.1 0.00000000000000000000000000000000000000000000000000000000001756 210.0
HFD2_k127_2550978_27 Belongs to the Dps family K04047 - - 0.000000000000000000000000000000000000000000000000000003617 195.0
HFD2_k127_2550978_28 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000002747 190.0
HFD2_k127_2550978_29 helix_turn_helix, cAMP Regulatory protein K01420,K15861 - - 0.000000000000000000000000000000000000000000000000006118 190.0
HFD2_k127_2550978_3 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 1.994e-196 619.0
HFD2_k127_2550978_30 Putative member of DMT superfamily (DUF486) K09922 - - 0.0000000000000000000000000000000000000000000167 165.0
HFD2_k127_2550978_31 Protein of unknown function (DUF1513) K09947 - - 0.0000000000000000000000000000000000000000008459 173.0
HFD2_k127_2550978_32 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000005005 146.0
HFD2_k127_2550978_33 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000001548 139.0
HFD2_k127_2550978_34 Ndr family K01055 - 3.1.1.24 0.00000000000000000000000000000001593 136.0
HFD2_k127_2550978_35 COGs COG3655 transcriptional regulator protein K07727 - - 0.0000000000000000000000004825 106.0
HFD2_k127_2550978_37 deoxyhypusine monooxygenase activity - - - 0.00000001782 63.0
HFD2_k127_2550978_4 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 619.0
HFD2_k127_2550978_5 Imelysin K07231 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004822 536.0
HFD2_k127_2550978_6 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009809 527.0
HFD2_k127_2550978_7 Multicopper oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 529.0
HFD2_k127_2550978_8 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K11103 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 507.0
HFD2_k127_2550978_9 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005728 498.0
HFD2_k127_263449_0 DGC domain - - - 0.000000000000000000000000000000001044 139.0
HFD2_k127_263449_1 Putative Fe-S cluster - - - 0.0000000000000000000000000000000537 134.0
HFD2_k127_263449_2 DGC domain - - - 0.00000000000000000000000000001119 123.0
HFD2_k127_263449_3 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000021 123.0
HFD2_k127_263449_4 OsmC-like protein - - - 0.00000000006764 64.0
HFD2_k127_2704878_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00410,K00412 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 574.0
HFD2_k127_2704878_1 Carbohydrate family 9 binding domain-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 545.0
HFD2_k127_2704878_10 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.000000000000000000000000000000000000000000000000000000000000000000002165 242.0
HFD2_k127_2704878_11 PhoD-like phosphatase, N-terminal domain K01113 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000001852 215.0
HFD2_k127_2704878_12 dienelactone hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000001559 218.0
HFD2_k127_2704878_13 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.0000000000000000000000000000000000000000000000000000000002747 206.0
HFD2_k127_2704878_14 Integral membrane protein TerC family - - - 0.00000000000000000000000000000000000000000000000000000001389 205.0
HFD2_k127_2704878_15 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000005748 166.0
HFD2_k127_2704878_16 Universal stress protein family - - - 0.00000000000000000000000004597 121.0
HFD2_k127_2704878_17 COG4257 Streptogramin lyase K18235 - - 0.0000000000000000000009039 111.0
HFD2_k127_2704878_19 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000001214 63.0
HFD2_k127_2704878_2 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 449.0
HFD2_k127_2704878_20 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000002092 49.0
HFD2_k127_2704878_3 Bacterial regulatory helix-turn-helix protein, lysR family K03566 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 433.0
HFD2_k127_2704878_4 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 - 1.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007834 436.0
HFD2_k127_2704878_5 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006136 325.0
HFD2_k127_2704878_6 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 317.0
HFD2_k127_2704878_7 Alpha beta hydrolase K01561 - 3.8.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004483 320.0
HFD2_k127_2704878_8 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002348 271.0
HFD2_k127_2704878_9 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00410,K00412 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002523 267.0
HFD2_k127_2715020_0 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 487.0
HFD2_k127_2715020_1 Aldehyde oxidase and xanthine dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 424.0
HFD2_k127_2715020_2 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 301.0
HFD2_k127_2715020_3 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000006301 244.0
HFD2_k127_2715020_4 leucyl aminopeptidase, aminopeptidase T K18028 - 1.13.11.9 0.00000000000000000000000000000000000000000000000000000000000679 222.0
HFD2_k127_2715020_5 PFAM AMP-dependent synthetase and ligase K00666 - - 0.000000000000000000000000000000000000000000000000000000007764 210.0
HFD2_k127_2715020_6 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.0000000000000000000000000000000000000001003 161.0
HFD2_k127_2715020_7 COG3090 TRAP-type C4-dicarboxylate transport system, small permease component - - - 0.0000000000000000000000002418 111.0
HFD2_k127_2725960_0 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000756 510.0
HFD2_k127_2725960_1 MmgE/PrpD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006806 347.0
HFD2_k127_2725960_2 Protein of unknown function (DUF992) - - - 0.0000000000000000000000000000000000009834 144.0
HFD2_k127_2728145_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. K07716 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000272 243.0
HFD2_k127_2728145_1 Putative Flp pilus-assembly TadE/G-like - - - 0.00000000000000000000001425 109.0
HFD2_k127_2728145_2 phosphatidylinositol 4-phosphate 5-kinase K00889 GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 2.7.1.68 0.00000000000000000129 93.0
HFD2_k127_2728145_4 Flp pilus assembly protein, pilin Flp K02651 - - 0.0000000004979 63.0
HFD2_k127_2728145_5 PFAM Flp Fap pilin component K02651 - - 0.00000000134 61.0
HFD2_k127_2728145_6 PilZ domain - - - 0.00003883 50.0
HFD2_k127_2790432_0 GTP-binding protein TypA K06207 - - 4.343e-275 857.0
HFD2_k127_2790432_1 Pentapeptide repeats (8 copies) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 395.0
HFD2_k127_2790432_10 Galactose oxidase, central domain - - - 0.0000000000000000000000000000000000000000000000000000000000000007258 231.0
HFD2_k127_2790432_11 Serine aminopeptidase, S33 K01048 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000001176 228.0
HFD2_k127_2790432_12 PFAM Alpha beta hydrolase fold-3 domain protein K14731 - 3.1.1.83 0.0000000000000000000000000000000000000000000000000000000005227 214.0
HFD2_k127_2790432_13 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000009879 188.0
HFD2_k127_2790432_14 Belongs to the small heat shock protein (HSP20) family K04080 - - 0.000000000000000000000000000000000000000000000000005368 186.0
HFD2_k127_2790432_15 Biopolymer transport protein ExbD/TolR K03559 - - 0.00000000000000000000000000000000000000000000002189 174.0
HFD2_k127_2790432_16 cheY-homologous receiver domain K13589 - - 0.00000000000000000000000000000000000000000000002846 172.0
HFD2_k127_2790432_17 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.0000000000000000000000000000000000000000000001279 171.0
HFD2_k127_2790432_18 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000002288 165.0
HFD2_k127_2790432_19 Glycine-zipper domain - - - 0.0000000000000000000000000000000000007177 144.0
HFD2_k127_2790432_2 PFAM Glycoside hydrolase, clan GH-D K07407 - 3.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008082 385.0
HFD2_k127_2790432_20 cell septum assembly - - - 0.0000000000000000000000000000000002388 149.0
HFD2_k127_2790432_21 Tetratricopeptide repeat - - - 0.000000000000000000000000000000003252 144.0
HFD2_k127_2790432_22 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000000000000000000009864 124.0
HFD2_k127_2790432_23 Tetratricopeptide repeat - - - 0.0000000000000000000000000258 123.0
HFD2_k127_2790432_25 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000000000000000002409 108.0
HFD2_k127_2790432_26 Transglycosylase SLT domain K00786,K08305 - - 0.000000000000000005189 87.0
HFD2_k127_2790432_27 TIGRFAM outer membrane autotransporter barrel domain - - - 0.000000000003232 81.0
HFD2_k127_2790432_3 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 333.0
HFD2_k127_2790432_4 COG4149 ABC-type molybdate transport system, permease component K02018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004434 299.0
HFD2_k127_2790432_5 N-formylglutamate amidohydrolase K01458 - 3.5.1.68 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 289.0
HFD2_k127_2790432_6 Inositol monophosphatase K01092,K18649 - 3.1.3.15,3.1.3.25,3.1.3.93 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001997 282.0
HFD2_k127_2790432_7 Amidohydrolase K22213 - 4.1.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000134 255.0
HFD2_k127_2790432_8 TonB dependent biopolymer transporter integral cytoplasmic membrane subunit, working with ExbD K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005531 246.0
HFD2_k127_2790432_9 Domain of unknown function (DUF1993) - - - 0.00000000000000000000000000000000000000000000000000000000000000001509 228.0
HFD2_k127_2822158_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 0.0 1106.0
HFD2_k127_2822158_1 Malic enzyme K00029 - 1.1.1.40 0.0 1047.0
HFD2_k127_2822158_10 COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K07303 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000633 468.0
HFD2_k127_2822158_11 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 452.0
HFD2_k127_2822158_12 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009236 376.0
HFD2_k127_2822158_13 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003331 377.0
HFD2_k127_2822158_14 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 K21029,K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 359.0
HFD2_k127_2822158_15 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008254 339.0
HFD2_k127_2822158_16 GPR1 FUN34 yaaH family protein K07034 GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006835,GO:0006846,GO:0006855,GO:0008028,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015077,GO:0015078,GO:0015123,GO:0015238,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015355,GO:0015360,GO:0015672,GO:0015711,GO:0015718,GO:0015740,GO:0015744,GO:0015849,GO:0015893,GO:0016020,GO:0022804,GO:0022857,GO:0022890,GO:0034220,GO:0035433,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0043893,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071422,GO:0071702,GO:0071944,GO:0098655,GO:0098656,GO:0098660,GO:0098662,GO:1902600,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000201 262.0
HFD2_k127_2822158_17 Alpha-1,2-mannosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001672 265.0
HFD2_k127_2822158_18 SMP-30 Gluconolaconase LRE domain protein K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000005381 253.0
HFD2_k127_2822158_19 Mitochondrial small ribosomal subunit Rsm22 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001311 259.0
HFD2_k127_2822158_2 MreB/Mbl protein K04043 - - 1.979e-318 984.0
HFD2_k127_2822158_20 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.000000000000000000000000000000000000000000000000000000000000000000003681 240.0
HFD2_k127_2822158_21 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000001201 240.0
HFD2_k127_2822158_22 - - - - 0.000000000000000000000000000000000000000000000000000000000000001001 240.0
HFD2_k127_2822158_23 2Fe-2S -binding domain protein K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000004761 218.0
HFD2_k127_2822158_24 Cytochrome P460 - - - 0.00000000000000000000000000000000000000000000000000000000001281 213.0
HFD2_k127_2822158_25 proteins of the AP superfamily - - - 0.00000000000000000000000000000000000000000000000000000004211 218.0
HFD2_k127_2822158_26 Universal stress protein - - - 0.0000000000000000000000000000000000000000000000000007888 187.0
HFD2_k127_2822158_27 decarboxylase K01607 - 4.1.1.44 0.0000000000000000000000000000000000000000000000000009481 190.0
HFD2_k127_2822158_28 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000000000000000001195 186.0
HFD2_k127_2822158_29 decarboxylase K01607 - 4.1.1.44 0.00000000000000000000000000000000000000000000000008356 187.0
HFD2_k127_2822158_3 This protein is involved in the repair of mismatches in DNA K03555 - - 1.097e-313 985.0
HFD2_k127_2822158_30 PIN domain K18828 - - 0.0000000000000000000000000000000000000000000000005909 177.0
HFD2_k127_2822158_31 COG2010 Cytochrome c, mono- and diheme variants - - - 0.0000000000000000000000000000000000000000000000008624 181.0
HFD2_k127_2822158_32 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000003155 173.0
HFD2_k127_2822158_33 protein SCO1 SenC K07152 - - 0.0000000000000000000000000000000000000000000281 169.0
HFD2_k127_2822158_34 Protein of unknown function, DUF - - - 0.000000000000000000000000000000000001849 151.0
HFD2_k127_2822158_35 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.000000000000000000000000000007207 129.0
HFD2_k127_2822158_36 Antidote-toxin recognition MazE, bacterial antitoxin K18829 - - 0.0000000000000000000000000009976 114.0
HFD2_k127_2822158_37 ParE toxin of type II toxin-antitoxin system, parDE K19092 - - 0.000000000000000000000000001443 115.0
HFD2_k127_2822158_38 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH K07746 - - 0.00000000000000000000000005673 111.0
HFD2_k127_2822158_4 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 1.301e-246 775.0
HFD2_k127_2822158_40 nuclease of the RecB family - - - 0.00000000000000000004278 99.0
HFD2_k127_2822158_41 COG4257 Streptogramin lyase - - - 0.00000000000000000005161 105.0
HFD2_k127_2822158_42 Zinc-finger domain - - - 0.0000000000000000001297 89.0
HFD2_k127_2822158_43 - - - - 0.000000000000000002185 92.0
HFD2_k127_2822158_44 Isochorismatase family - - - 0.0000000000000001907 87.0
HFD2_k127_2822158_45 - - - - 0.00000000000006134 78.0
HFD2_k127_2822158_46 Tetratricopeptide repeat - - - 0.00000000000008969 81.0
HFD2_k127_2822158_47 Asp Glu Hydantoin racemase family protein K01799 - 5.2.1.1 0.00001781 51.0
HFD2_k127_2822158_5 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate K00108 - 1.1.99.1 1.25e-237 745.0
HFD2_k127_2822158_6 - - - - 5.605e-230 732.0
HFD2_k127_2822158_7 Carbohydrate family 9 binding domain-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 562.0
HFD2_k127_2822158_8 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 492.0
HFD2_k127_2822158_9 Dienelactone hydrolase K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 475.0
HFD2_k127_2822250_0 Methyltransferase - - - 0.0000000000000000000000000000000000000000001656 175.0
HFD2_k127_2822250_1 PFAM Excinuclease ABC C subunit domain protein K07461 - - 0.0000000000000000000000000000000000031 140.0
HFD2_k127_2822250_2 Peptidase family M28 - - - 0.000000000000000000000000000000001773 129.0
HFD2_k127_2822250_3 PFAM Patatin K07001 - - 0.0000000000000000000000005527 115.0
HFD2_k127_2822250_4 PFAM Patatin K07001 - - 0.0000000000000000000001412 104.0
HFD2_k127_2822250_5 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.00000008907 55.0
HFD2_k127_2830065_0 Putative transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004728 548.0
HFD2_k127_2830065_1 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000005072 232.0
HFD2_k127_2830065_2 Belongs to the 'phage' integrase family - - - 0.000000000000000000000009243 104.0
HFD2_k127_2830065_3 - - - - 0.00000006143 59.0
HFD2_k127_2851549_0 PQQ-like domain K00114,K20937 - 1.1.2.8,1.1.5.11 9.949e-199 634.0
HFD2_k127_2851549_1 fatty acid transporter K02106 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 452.0
HFD2_k127_2851549_10 Bacterial extracellular solute-binding protein K02020 - - 0.0000000000000000000001168 111.0
HFD2_k127_2851549_11 - - - - 0.000000000000000000534 97.0
HFD2_k127_2851549_12 WHG domain - - - 0.00000000444 68.0
HFD2_k127_2851549_13 thiamine-containing compound biosynthetic process K02051 - - 0.000000007501 67.0
HFD2_k127_2851549_2 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 428.0
HFD2_k127_2851549_3 L-lactate dehydrogenase K00101,K00467,K16422 - 1.1.2.3,1.1.3.46,1.13.12.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 349.0
HFD2_k127_2851549_4 L-lactate dehydrogenase K00101,K00467,K16422 - 1.1.2.3,1.1.3.46,1.13.12.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 340.0
HFD2_k127_2851549_5 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000008329 267.0
HFD2_k127_2851549_6 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003094 252.0
HFD2_k127_2851549_7 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000006436 192.0
HFD2_k127_2851549_8 Thioesterase superfamily K01075 - 3.1.2.23 0.0000000000000000000000000000000007484 144.0
HFD2_k127_2851549_9 F420H(2)-dependent quinone reductase - - - 0.000000000000000000000000000000002821 134.0
HFD2_k127_2936002_0 Carbohydrate family 9 binding domain-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005135 566.0
HFD2_k127_2936002_1 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 421.0
HFD2_k127_2936002_2 metal-dependent hydrolase with the TIM-barrel fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 311.0
HFD2_k127_2936002_4 antibiotic catabolic process K13277,K20276 - - 0.000000000000000000000000000000000000000000000000000000005941 225.0
HFD2_k127_2936002_5 - - - - 0.000000000000000000000001982 115.0
HFD2_k127_2936002_6 Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria - - - 0.000000002043 62.0
HFD2_k127_2936002_7 - - - - 0.000002823 52.0
HFD2_k127_2939796_0 glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 2597.0
HFD2_k127_2939796_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0 1170.0
HFD2_k127_2939796_10 protocatechuate 3,4-dioxygenase, beta subunit' K00449 - 1.13.11.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 314.0
HFD2_k127_2939796_11 spore germination - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 305.0
HFD2_k127_2939796_12 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002771 303.0
HFD2_k127_2939796_13 Aldolase/RraA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005322 282.0
HFD2_k127_2939796_14 Dioxygenase K00448 - 1.13.11.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000003315 261.0
HFD2_k127_2939796_15 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000003552 255.0
HFD2_k127_2939796_16 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000001369 235.0
HFD2_k127_2939796_17 ethanolamine utilization protein K04019 GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0030091,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009,GO:0071704,GO:1901564 - 0.0000000000000000000000000002332 116.0
HFD2_k127_2939796_2 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases K00266 - 1.4.1.13,1.4.1.14 4.313e-254 794.0
HFD2_k127_2939796_3 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 538.0
HFD2_k127_2939796_4 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 518.0
HFD2_k127_2939796_5 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 428.0
HFD2_k127_2939796_6 PFAM major facilitator superfamily MFS_1 K08169 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 415.0
HFD2_k127_2939796_7 oxidoreductase FAD NAD(P)-binding domain protein K18069,K21607 - 1.1.1.404 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004262 374.0
HFD2_k127_2939796_8 MmgE/PrpD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 366.0
HFD2_k127_2939796_9 Sugar (and other) transporter K08195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 328.0
HFD2_k127_2951687_0 DEAD/H associated K03724 - - 0.0 1832.0
HFD2_k127_2951687_1 Conserved hypothetical protein 698 - - - 2.251e-197 623.0
HFD2_k127_2951687_2 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004495 276.0
HFD2_k127_2951687_3 SMART Prolyl 4-hydroxylase, alpha subunit - - - 0.000000000000000000000000000000000000000000000001038 186.0
HFD2_k127_2951687_4 2OG-Fe(II) oxygenase superfamily - - - 0.0000000000000000000000000000000000003334 150.0
HFD2_k127_2951687_5 Clp protease K01358 - 3.4.21.92 0.00000000000000000000000000001156 124.0
HFD2_k127_2951687_6 - - - - 0.000000000000000000003797 95.0
HFD2_k127_2956880_0 glycosyl hydrolase, BNR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006817 558.0
HFD2_k127_2956880_1 PFAM von Willebrand factor type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007732 381.0
HFD2_k127_2956880_2 oxidoreductase activity K02012,K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004537 339.0
HFD2_k127_2956880_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002397 260.0
HFD2_k127_2956880_4 Transposase DDE domain - - - 0.0000001287 57.0
HFD2_k127_298557_0 Transposase (IS116 IS110 IS902 family) K07486 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003312 545.0
HFD2_k127_2997653_0 Aerotolerance regulator N-terminal - - - 1.822e-218 704.0
HFD2_k127_2997653_1 membrane - - - 2.895e-211 679.0
HFD2_k127_2997653_2 With MotB forms the ion channels that couple flagellar rotation to proton sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine K02556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006823 453.0
HFD2_k127_2997653_3 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007499 336.0
HFD2_k127_2997653_4 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000005017 169.0
HFD2_k127_2997653_5 Response regulator receiver - - - 0.0000000000000000000000000000000000000002351 157.0
HFD2_k127_2997653_6 - - - - 0.0000000000000000000000002845 110.0
HFD2_k127_2997653_7 - - - - 0.0000000000000000000000009877 108.0
HFD2_k127_2997653_8 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01754 - 4.3.1.19 0.00000000000000000007466 91.0
HFD2_k127_3033365_0 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000000000000000000000000000000000000000004513 202.0
HFD2_k127_3033365_1 MacB-like periplasmic core domain - - - 0.000000000000000000002186 100.0
HFD2_k127_3033365_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K02078,K13611,K15337 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.000000000000001006 81.0
HFD2_k127_30553_0 Thiamine pyrophosphate enzyme, central domain - - - 2.594e-244 767.0
HFD2_k127_30553_1 AMP-binding enzyme C-terminal domain K02363 - 2.7.7.58,6.3.2.14 4.301e-219 693.0
HFD2_k127_30553_10 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 297.0
HFD2_k127_30553_11 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003515 251.0
HFD2_k127_30553_12 enoyl-CoA hydratase K13766,K13779,K15312 - 4.2.1.18,4.2.1.57 0.000000000000000000000000000000000000000000000000000000000001231 218.0
HFD2_k127_30553_13 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000000000000000000000000000000001486 197.0
HFD2_k127_30553_14 Protein of unknown function (DUF3775) - - - 0.0000000000000000000000000000000000000005919 153.0
HFD2_k127_30553_15 COG0471 Di- and tricarboxylate transporters - - - 0.00000000000000000000000004584 123.0
HFD2_k127_30553_16 Tripartite tricarboxylate transporter TctB family - - - 0.00000000000000001831 88.0
HFD2_k127_30553_17 Amidohydrolase K07045 - - 0.000000000000003168 88.0
HFD2_k127_30553_18 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000000000000006721 80.0
HFD2_k127_30553_19 - - - - 0.0000000000002185 76.0
HFD2_k127_30553_2 Tripartite tricarboxylate transporter TctA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 524.0
HFD2_k127_30553_20 Bacterial protein of unknown function (DUF883) - - - 0.00000009817 57.0
HFD2_k127_30553_3 PFAM peptidase M19 renal dipeptidase K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 465.0
HFD2_k127_30553_4 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007098 421.0
HFD2_k127_30553_5 phosphogluconate dehydrogenase (decarboxylating) activity K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004766 355.0
HFD2_k127_30553_6 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003879 341.0
HFD2_k127_30553_7 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 339.0
HFD2_k127_30553_8 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 299.0
HFD2_k127_30553_9 Auxin binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 291.0
HFD2_k127_3070574_0 Lactonase, 7-bladed beta-propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 466.0
HFD2_k127_3070574_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004737 366.0
HFD2_k127_3075181_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K13810 - 2.2.1.2,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003638 411.0
HFD2_k127_3075181_1 - - - - 0.00000000001828 75.0
HFD2_k127_3075181_2 GDSL-like Lipase/Acylhydrolase K10804 - 3.1.1.5 0.0000008935 59.0
HFD2_k127_3079257_0 PQQ-like domain K00114,K17760,K22473 - 1.1.2.8,1.1.5.5,1.1.9.1 1.264e-254 803.0
HFD2_k127_3079257_1 Belongs to the UbiD family K03182 - 4.1.1.98 2.2e-247 779.0
HFD2_k127_3079257_10 Adenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000343 296.0
HFD2_k127_3079257_11 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000000000000000000005504 265.0
HFD2_k127_3079257_12 Inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000001141 253.0
HFD2_k127_3079257_13 Ribosomal protein L11 methyltransferase (PrmA) - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010565,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018022,GO:0018023,GO:0018193,GO:0018205,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031329,GO:0031330,GO:0031974,GO:0031998,GO:0031999,GO:0032259,GO:0036211,GO:0043086,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043414,GO:0043467,GO:0044092,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045833,GO:0045922,GO:0046320,GO:0046322,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0050994,GO:0050995,GO:0051341,GO:0051354,GO:0062012,GO:0062014,GO:0065007,GO:0065009,GO:0070013,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1904732,GO:1904733,GO:1904735,GO:1904736 - 0.0000000000000000000000000000000000000000000000000000000000000000001569 240.0
HFD2_k127_3079257_14 sequence-specific DNA binding - - - 0.0000000000000000000000000000000000000000000392 163.0
HFD2_k127_3079257_15 PIN domain - - - 0.000000000000000000000000000000000000001446 154.0
HFD2_k127_3079257_16 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0000000000000000000000000000000003683 135.0
HFD2_k127_3079257_17 gag-polyprotein putative aspartyl protease - - - 0.00000000000000000000000000249 126.0
HFD2_k127_3079257_18 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000002467 103.0
HFD2_k127_3079257_19 - - - - 0.00000000000000000001639 102.0
HFD2_k127_3079257_2 glutamate--cysteine ligase K01919 - 6.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006673 597.0
HFD2_k127_3079257_20 (twin-arginine translocation) pathway signal - - - 0.000000000000000002236 92.0
HFD2_k127_3079257_22 SnoaL-like domain - - - 0.0000000003037 66.0
HFD2_k127_3079257_3 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005601 572.0
HFD2_k127_3079257_4 C-terminus of AA_permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003866 541.0
HFD2_k127_3079257_5 Putative modulator of DNA gyrase K03592 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 531.0
HFD2_k127_3079257_6 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 535.0
HFD2_k127_3079257_7 ABC-type multidrug transport system, ATPase and permease K02021,K06147,K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 509.0
HFD2_k127_3079257_8 Major Facilitator Superfamily K13021 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 408.0
HFD2_k127_3079257_9 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179,K06125 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 338.0
HFD2_k127_3090088_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 4.223e-311 964.0
HFD2_k127_3090088_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008055 557.0
HFD2_k127_3090088_10 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 GO:0003674,GO:0003824,GO:0004733,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.4.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000506 294.0
HFD2_k127_3090088_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003085 295.0
HFD2_k127_3090088_12 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008468 284.0
HFD2_k127_3090088_13 Peptidase C13 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000161 267.0
HFD2_k127_3090088_14 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000004848 253.0
HFD2_k127_3090088_15 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000001458 183.0
HFD2_k127_3090088_16 Belongs to the P(II) protein family K04752 GO:0003674,GO:0005488,GO:0005515,GO:0006808,GO:0008150,GO:0042802,GO:0045848,GO:0048518,GO:0050789,GO:0065007 - 0.000000000000000000000000000000000000000000127 162.0
HFD2_k127_3090088_17 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000005586 171.0
HFD2_k127_3090088_18 Phytanoyl-CoA dioxygenase PhyH family protein - - - 0.0000000000000000000000000000000000001114 154.0
HFD2_k127_3090088_19 PIN domain K07064 GO:0005575,GO:0005576 - 0.0000000000000000000000000000000000003153 145.0
HFD2_k127_3090088_2 PFAM Ammonium Transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007086 503.0
HFD2_k127_3090088_20 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000003323 115.0
HFD2_k127_3090088_21 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000000000000002743 99.0
HFD2_k127_3090088_22 PFAM Glycosyl transferase family 2 K07011 - - 0.000000000000000003378 95.0
HFD2_k127_3090088_23 - - GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007 - 0.0000000000000002508 82.0
HFD2_k127_3090088_24 NMT1-like family K02051 - - 0.00002462 56.0
HFD2_k127_3090088_25 - - - - 0.0000691 53.0
HFD2_k127_3090088_26 PIN domain - - - 0.0002845 44.0
HFD2_k127_3090088_27 photosystem II stabilization K02237 - - 0.0006163 49.0
HFD2_k127_3090088_3 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004719 413.0
HFD2_k127_3090088_4 Histone deacetylase domain K04768 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003499 402.0
HFD2_k127_3090088_5 signal peptide peptidase K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 389.0
HFD2_k127_3090088_6 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005655 340.0
HFD2_k127_3090088_7 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K00557,K03215 - 2.1.1.190,2.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 333.0
HFD2_k127_3090088_8 DnaJ C terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 328.0
HFD2_k127_3090088_9 esterase K01432 - 3.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007664 328.0
HFD2_k127_3180417_0 Tannase and feruloyl esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008996 467.0
HFD2_k127_3180417_1 CRISPR associated protein Cas1 - - - 0.00000000000000000000000203 108.0
HFD2_k127_3180417_2 Pretoxin HINT domain K15125 - - 0.000000000000000000000004276 107.0
HFD2_k127_3180417_3 - - - - 0.00000000000000000000006356 100.0
HFD2_k127_3180417_4 self proteolysis K07114 - - 0.0000000000000000001814 92.0
HFD2_k127_3180417_6 - - - - 0.00008495 50.0
HFD2_k127_3183013_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 1.426e-241 787.0
HFD2_k127_3183013_1 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 7.775e-220 691.0
HFD2_k127_3183013_2 Adenylosuccinate lyase C-terminus K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 7.254e-219 685.0
HFD2_k127_3183013_3 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 302.0
HFD2_k127_3183013_4 TIGRFAM 40-residue YVTN family beta-propeller repeat protein - - - 0.000000000000000000001044 108.0
HFD2_k127_3183013_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.0000000001698 73.0
HFD2_k127_3183013_6 copper resistance protein K07156 - - 0.00000003532 66.0
HFD2_k127_3188916_0 Glycosyltransferase family 28 C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003374 497.0
HFD2_k127_3188916_1 ABC transporter transmembrane region K02021 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009837 309.0
HFD2_k127_3188916_2 Glycosyl transferases group 1 - - - 0.00000000000000001933 83.0
HFD2_k127_3190875_0 His Kinase A (phosphoacceptor) domain K13587 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 525.0
HFD2_k127_3190875_1 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006448 424.0
HFD2_k127_3190875_10 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000001965 134.0
HFD2_k127_3190875_11 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.00000000000000000000001509 105.0
HFD2_k127_3190875_12 Role in flagellar biosynthesis K02420 - - 0.0000000000000000000007749 97.0
HFD2_k127_3190875_14 Flagellar hook-basal body complex protein FliE K02408 - - 0.000000000000676 72.0
HFD2_k127_3190875_15 Flagellar biosynthesis protein, FliO K02418 - - 0.0000002343 56.0
HFD2_k127_3190875_2 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 338.0
HFD2_k127_3190875_3 ThiF family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 331.0
HFD2_k127_3190875_4 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 310.0
HFD2_k127_3190875_5 Plays a role in the flagellum-specific transport system K02419 - - 0.00000000000000000000000000000000000000000000000000000000000000000001443 245.0
HFD2_k127_3190875_6 Bacterial export proteins, family 1 K02421 - - 0.000000000000000000000000000000000000000000000000000000004464 211.0
HFD2_k127_3190875_7 - - - - 0.000000000000000000000000000000000000000000000000003619 189.0
HFD2_k127_3190875_8 Flagellar basal body rod FlgEFG protein C-terminal K02388 - - 0.0000000000000000000000000000000000000000008074 160.0
HFD2_k127_3191168_0 Type II/IV secretion system protein K02283 - - 3.21e-230 721.0
HFD2_k127_3191168_1 AAA domain K02282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 487.0
HFD2_k127_3191168_10 COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001445 258.0
HFD2_k127_3191168_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000001075 241.0
HFD2_k127_3191168_12 pilus assembly protein CpaB K02279 - - 0.00000000000000000000000000000000000000000000000005999 188.0
HFD2_k127_3191168_13 Glycosyltransferase family 87 - - - 0.000000000000000000000000000000000000000000000002755 184.0
HFD2_k127_3191168_14 Cytochrome c K08738 - - 0.00000000000000000000000000000000000000004425 161.0
HFD2_k127_3191168_15 Type IV leader peptidase family K02278 - 3.4.23.43 0.000000000000000000000000000000000774 136.0
HFD2_k127_3191168_16 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000000000000000001137 137.0
HFD2_k127_3191168_17 Pilus biogenesis CpaD protein (pilus_cpaD) K02281 - - 0.00000000000000000000000000000004893 133.0
HFD2_k127_3191168_18 Glycosyltransferase family 87 - - - 0.00000000000000000000006806 102.0
HFD2_k127_3191168_19 PFAM GtrA family protein - - - 0.000000000000000000001174 100.0
HFD2_k127_3191168_2 Belongs to the peptidase M17 family K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 479.0
HFD2_k127_3191168_20 Flp Fap pilin component K02651 - - 0.000000000001191 69.0
HFD2_k127_3191168_21 Pilus formation protein N terminal region - - - 0.000000000004853 74.0
HFD2_k127_3191168_22 Flp Fap pilin component K02651 - - 0.000000009122 60.0
HFD2_k127_3191168_3 FAD binding domain K00103 - 1.1.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 456.0
HFD2_k127_3191168_4 Pilus formation protein N terminal region K02280 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 430.0
HFD2_k127_3191168_5 type II secretion system K12511 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004332 333.0
HFD2_k127_3191168_6 Type II secretion system (T2SS), protein F K12510 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004836 291.0
HFD2_k127_3191168_7 NlpC/P60 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001324 278.0
HFD2_k127_3191168_8 TRAP transporter solute receptor TAXI family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002178 264.0
HFD2_k127_3191168_9 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005192 252.0
HFD2_k127_3213832_0 PFAM tRNA synthetase, class II (D, K and N) K04568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004616 459.0
HFD2_k127_3213832_1 TIGRFAM lysine 2,3-aminomutase YodO family protein K01843 - 5.4.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009468 451.0
HFD2_k127_3213832_2 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001163 281.0
HFD2_k127_3213832_3 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008988,GO:0009451,GO:0009987,GO:0010467,GO:0015976,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036307,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.266 0.0000000000000000000000000000000000000000000000000000000000000000000844 240.0
HFD2_k127_3213832_4 Phage integrase family - - - 0.00000000000000000000000000000385 121.0
HFD2_k127_3213832_5 Recombinase zinc beta ribbon domain - - - 0.0000000000005139 73.0
HFD2_k127_3224290_0 PFAM aldehyde oxidase and xanthine dehydrogenase a b hammerhead K16877 - 1.3.99.8 0.0 1105.0
HFD2_k127_3224290_1 PFAM General substrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 601.0
HFD2_k127_3224290_10 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000000001505 182.0
HFD2_k127_3224290_11 - - - - 0.00000000000000000000000000000000000000000006038 167.0
HFD2_k127_3224290_12 PFAM transposase IS116 IS110 IS902 family K07486 - - 0.000000000000000000000000000000000000001102 149.0
HFD2_k127_3224290_13 - - - - 0.000000000000000000000000000004119 133.0
HFD2_k127_3224290_2 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003296 508.0
HFD2_k127_3224290_3 PrpF protein K16514 - 5.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 422.0
HFD2_k127_3224290_4 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007921 400.0
HFD2_k127_3224290_5 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003918 375.0
HFD2_k127_3224290_6 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 293.0
HFD2_k127_3224290_7 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004514 283.0
HFD2_k127_3224290_8 carbon monoxide dehydrogenase K03519,K16878 - 1.2.5.3,1.3.99.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001699 274.0
HFD2_k127_3224290_9 [2Fe-2S] binding domain K03518,K16879 - 1.2.5.3,1.3.99.8 0.000000000000000000000000000000000000000000000000000000000001029 215.0
HFD2_k127_3249622_0 Glycosyl transferase family 41 - - - 5.321e-201 650.0
HFD2_k127_3249622_1 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004153 341.0
HFD2_k127_3249622_10 - - - - 0.0000000000000000000000001401 115.0
HFD2_k127_3249622_11 - - - - 0.000000000000000000000002979 114.0
HFD2_k127_3249622_12 - - - - 0.00000000000000000000000496 112.0
HFD2_k127_3249622_13 - - - - 0.000000000000000000000009133 111.0
HFD2_k127_3249622_14 - - - - 0.0000000000000000000003049 105.0
HFD2_k127_3249622_15 - - - - 0.0000000000000000000003796 107.0
HFD2_k127_3249622_16 - - - - 0.0000000000000000000007853 106.0
HFD2_k127_3249622_17 - - - - 0.00000000000000000002181 103.0
HFD2_k127_3249622_18 - - - - 0.00000000000000000003173 102.0
HFD2_k127_3249622_19 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000001394 101.0
HFD2_k127_3249622_2 ATPases associated with a variety of cellular activities K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 329.0
HFD2_k127_3249622_23 Haem-degrading - - - 0.0000000001073 68.0
HFD2_k127_3249622_24 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000002418 63.0
HFD2_k127_3249622_25 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00003863 55.0
HFD2_k127_3249622_3 TonB dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000004946 267.0
HFD2_k127_3249622_4 Peroxiredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000001138 222.0
HFD2_k127_3249622_5 MlaD protein K02067,K06192 - - 0.0000000000000000000000000000000000000000000000000000007211 204.0
HFD2_k127_3249622_6 tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000002212 200.0
HFD2_k127_3249622_7 ABC-type transport auxiliary lipoprotein component K18480 - - 0.000000000000000000000000000000008989 138.0
HFD2_k127_3249622_8 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000001396 124.0
HFD2_k127_3249622_9 - - - - 0.000000000000000000000000006398 121.0
HFD2_k127_3263727_0 Caudovirus prohead serine protease - - - 0.0000000000000000000000000000711 129.0
HFD2_k127_3263727_1 Pyridoxamine 5'-phosphate oxidase K09979 - - 0.00000000003119 71.0
HFD2_k127_3263727_2 lipolytic protein G-D-S-L family - - - 0.00000000009766 74.0
HFD2_k127_3315573_0 coenzyme F390 K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000181 301.0
HFD2_k127_3315573_1 Uncharacterized protein conserved in bacteria (DUF2237) K09966 - - 0.00000000000000000000000000000000000000000000000000000000000001077 218.0
HFD2_k127_3315573_2 Glyoxalase-like domain K08234 - - 0.000000000000000000000000000000000000000000000000000001198 196.0
HFD2_k127_3315573_3 - - - - 0.000000000000006163 78.0
HFD2_k127_3315573_4 Sel1-like repeats. K07126 - - 0.0000000000004076 77.0
HFD2_k127_3315573_5 - - - - 0.000001455 56.0
HFD2_k127_3315573_6 - - - - 0.000003728 54.0
HFD2_k127_3346881_0 von Willebrand factor (vWF) type A domain - - - 4.266e-269 869.0
HFD2_k127_3346881_1 Cation efflux family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009309 301.0
HFD2_k127_3346881_2 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008891 284.0
HFD2_k127_3346881_3 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000002437 245.0
HFD2_k127_3346881_4 Haem-degrading K11477 - - 0.00000000000000000000000000001063 123.0
HFD2_k127_3346881_5 structural constituent of ribosome K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000005816 114.0
HFD2_k127_3346881_6 -acetyltransferase - - - 0.0000000000000000000000000007509 119.0
HFD2_k127_3346881_7 Aldehyde dehydrogenase family K00140 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006950,GO:0006979,GO:0008150,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050896 1.2.1.18,1.2.1.27 0.00000000000000000000000005013 107.0
HFD2_k127_3346881_8 acetyltransferase K17840 - 2.3.1.59 0.000000000000000216 86.0
HFD2_k127_3346881_9 rpsU-divergently transcribed protein K18587 - - 0.00006789 49.0
HFD2_k127_3378394_0 hydrolase activity, hydrolyzing O-glycosyl compounds K01176,K21575 - 3.2.1.1,3.2.1.135 5.559e-212 676.0
HFD2_k127_3378394_1 belongs to the aldehyde dehydrogenase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006221 602.0
HFD2_k127_3378394_2 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001507 228.0
HFD2_k127_3378394_3 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.000000000000000000000000000005956 130.0
HFD2_k127_3378394_4 COG1405 Transcription initiation factor TFIIIB, Brf1 subunit Transcription initiation factor TFIIB - - - 0.00000000000000000003109 95.0
HFD2_k127_3378394_5 Aldo/keto reductase family - - - 0.000000000000005225 76.0
HFD2_k127_3378394_6 - - - - 0.000000000005006 71.0
HFD2_k127_3378394_7 Belongs to the peptidase S8 family K12685 - - 0.0000005991 61.0
HFD2_k127_3378394_8 Methyltransferase domain - - - 0.000009926 53.0
HFD2_k127_3385455_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 1.712e-309 958.0
HFD2_k127_3385455_1 Belongs to the UbiD family K03182,K16874 - 4.1.1.98 9.159e-286 883.0
HFD2_k127_3385455_10 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K06989 - 1.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003849 342.0
HFD2_k127_3385455_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005049 285.0
HFD2_k127_3385455_12 dihydrofolate reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006586 274.0
HFD2_k127_3385455_13 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000001603 231.0
HFD2_k127_3385455_14 - - - - 0.00000000000000000000000000000000000000000000000000000000000000159 232.0
HFD2_k127_3385455_15 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000000000000000000000000000000000000007166 213.0
HFD2_k127_3385455_16 decarboxylase K01607 - 4.1.1.44 0.0000000000000000000000000000000000000000000000000000000005901 209.0
HFD2_k127_3385455_17 growth inhibitor K07171 - - 0.000000000000000000000000000000000000000000104 165.0
HFD2_k127_3385455_18 - - - - 0.00000000000000000000000000000000000000003355 169.0
HFD2_k127_3385455_19 sterol desaturase - - - 0.000000000000000000000000003726 123.0
HFD2_k127_3385455_2 PFAM AMP-dependent synthetase and ligase - - - 5.838e-228 721.0
HFD2_k127_3385455_20 - - - - 0.000000000000000000000000006179 111.0
HFD2_k127_3385455_21 Glyoxalase-like domain - - - 0.000000000000000000000008283 104.0
HFD2_k127_3385455_22 - - - - 0.00000000000000000000002845 115.0
HFD2_k127_3385455_23 Protein of unknown function (DUF3018) - - - 0.000000000000000466 85.0
HFD2_k127_3385455_24 Haem-degrading K11477 - - 0.0000000003557 68.0
HFD2_k127_3385455_25 COG3637 Opacity protein and related surface antigens - - - 0.000579 49.0
HFD2_k127_3385455_3 Zinc-binding dehydrogenase K00001 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007979 552.0
HFD2_k127_3385455_4 aromatic amino acid beta-eliminating lyase threonine aldolase K01739 - 2.5.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 524.0
HFD2_k127_3385455_5 COG2230 Cyclopropane fatty acid synthase and related methyltransferases K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008195 481.0
HFD2_k127_3385455_6 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 441.0
HFD2_k127_3385455_7 Integrase core domain K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 416.0
HFD2_k127_3385455_8 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 400.0
HFD2_k127_3385455_9 OST-HTH/LOTUS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003478 384.0
HFD2_k127_339916_0 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006452 308.0
HFD2_k127_339916_1 Response regulator receiver domain K03413 - - 0.000000000000000000000000000000000000000000000000699 179.0
HFD2_k127_339916_2 COG0642 Signal transduction histidine kinase K13588 - - 0.0000000000000001258 84.0
HFD2_k127_3442401_0 Cytochrome C oxidase, cbb3-type, subunit III - - - 1.399e-240 754.0
HFD2_k127_3442401_1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 1.456e-215 692.0
HFD2_k127_3442401_10 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006154 314.0
HFD2_k127_3442401_11 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001601 269.0
HFD2_k127_3442401_12 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000207 273.0
HFD2_k127_3442401_13 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001645 260.0
HFD2_k127_3442401_14 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000171 268.0
HFD2_k127_3442401_15 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001684 250.0
HFD2_k127_3442401_16 carboxylic ester hydrolase activity - GO:0003674,GO:0003824,GO:0006629,GO:0008150,GO:0008152,GO:0009056,GO:0016042,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0071704,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000002748 237.0
HFD2_k127_3442401_17 transcriptional regulator - - - 0.00000000000000449 80.0
HFD2_k127_3442401_18 - - - - 0.00000000007374 64.0
HFD2_k127_3442401_19 Cell Wall K01448 - 3.5.1.28 0.0001612 53.0
HFD2_k127_3442401_2 Amidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 573.0
HFD2_k127_3442401_3 Carbohydrate family 9 binding domain-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004193 505.0
HFD2_k127_3442401_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 479.0
HFD2_k127_3442401_5 PFAM NADH Ubiquinone plastoquinone (complex I) K12141 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 448.0
HFD2_k127_3442401_6 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 449.0
HFD2_k127_3442401_7 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007108 408.0
HFD2_k127_3442401_8 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005504 353.0
HFD2_k127_3442401_9 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 317.0
HFD2_k127_3512232_0 Type II/IV secretion system protein K02283,K20527 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 595.0
HFD2_k127_3512232_1 Belongs to the GSP D family K02280 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005139 338.0
HFD2_k127_3512232_10 Tetratricopeptide repeat - - - 0.0000000005748 71.0
HFD2_k127_3512232_2 pilus assembly protein TadB K12510 - - 0.0000000000000000000000000000000000000000000000000000000000000000005019 240.0
HFD2_k127_3512232_3 Type II secretion system (T2SS), protein F K12511 - - 0.00000000000000000000000000000000000000000000000000000000000000022 232.0
HFD2_k127_3512232_4 Flp pilus assembly protein, ATPase CpaE K02282 - - 0.0000000000000000000000000000000000000000000000000000000000000004704 243.0
HFD2_k127_3512232_5 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.0000000000000000000000000000000000000000002806 170.0
HFD2_k127_3512232_6 Belongs to the Orn Lys Arg decarboxylase class-II family K01581 - 4.1.1.17 0.00000000000000000000000000000000003079 138.0
HFD2_k127_3512232_7 Type IV leader peptidase family - - - 0.000000000005078 74.0
HFD2_k127_3512232_8 Pilus biogenesis CpaD protein (pilus_cpaD) K02281 - - 0.00000000003769 72.0
HFD2_k127_3512232_9 PFAM Flp Fap pilin component K02651 - - 0.0000000004971 62.0
HFD2_k127_3519045_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1114.0
HFD2_k127_3519045_1 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 417.0
HFD2_k127_3519045_11 ABC-type transport system, permease components - - - 0.0000000000000000000000000000000000001572 151.0
HFD2_k127_3519045_12 - - - - 0.000000000000000000002191 100.0
HFD2_k127_3519045_13 - - - - 0.000000000002126 73.0
HFD2_k127_3519045_2 Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003205 421.0
HFD2_k127_3519045_3 D-isomer specific 2-hydroxyacid dehydrogenase K00018 - 1.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 393.0
HFD2_k127_3519045_5 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002802 261.0
HFD2_k127_3519045_6 fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.000000000000000000000000000000000000000000000000000000000003321 222.0
HFD2_k127_3519045_7 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000007828 218.0
HFD2_k127_3519045_8 Arylesterase - - - 0.00000000000000000000000000000000000000000000000002886 198.0
HFD2_k127_3519045_9 PFAM Uncharacterised protein family (UPF0153) - - - 0.000000000000000000000000000000000000000000001359 175.0
HFD2_k127_3535460_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 592.0
HFD2_k127_3535460_1 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007261 522.0
HFD2_k127_3535460_11 Serine aminopeptidase, S33 - - - 0.000000001681 59.0
HFD2_k127_3535460_2 PFAM NAD dependent epimerase dehydratase family K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 312.0
HFD2_k127_3535460_3 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000003232 240.0
HFD2_k127_3535460_4 - - - - 0.00000000000000000000000000000118 128.0
HFD2_k127_3535460_5 Transposase - - - 0.000000000000000000001207 102.0
HFD2_k127_3535460_8 - - - - 0.0000000000008042 78.0
HFD2_k127_3535460_9 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000009183 68.0
HFD2_k127_3553396_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 570.0
HFD2_k127_3553396_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001023 271.0
HFD2_k127_357772_0 succinate dehydrogenase fumarate reductase, flavoprotein subunit K00394 - 1.8.99.2 0.0 1025.0
HFD2_k127_357772_1 Fumarate reductase flavoprotein C-term K00244 - 1.3.5.4 1.139e-294 916.0
HFD2_k127_357772_10 Transporter, DASS family K11106,K14445 - - 0.000000000000000000000000000000000000000000000000000000000000000000007445 237.0
HFD2_k127_357772_11 reductase beta subunit K00395 - 1.8.99.2 0.00000000000000000000000000000000000000000000000000000000000000001723 227.0
HFD2_k127_357772_12 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.00000000000000000000000000000000000000000000000000001008 198.0
HFD2_k127_357772_13 Thioredoxin - - - 0.00000000000000000000000000000000000000000009477 169.0
HFD2_k127_357772_14 Succinate dehydrogenase/Fumarate reductase transmembrane subunit - - - 0.0000000000000000000000000000000005435 137.0
HFD2_k127_357772_15 DsrE/DsrF-like family K09004 - - 0.000000000000000000000000000000009536 133.0
HFD2_k127_357772_16 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00247 - - 0.0000000000000000000000000003822 122.0
HFD2_k127_357772_17 - - - - 0.0000000000000002423 92.0
HFD2_k127_357772_18 - - - - 0.000000000005243 72.0
HFD2_k127_357772_19 Autotransporter beta-domain - - - 0.00000000008223 66.0
HFD2_k127_357772_2 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 2.569e-259 809.0
HFD2_k127_357772_20 Belongs to the ompA family - - - 0.0000000003186 66.0
HFD2_k127_357772_21 Serine threonine-protein kinase - GO:0003674,GO:0003824,GO:0004672,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0035556,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0140096,GO:1901564 - 0.00000003189 60.0
HFD2_k127_357772_3 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002967 525.0
HFD2_k127_357772_4 Fumarate hydratase (Fumerase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 480.0
HFD2_k127_357772_5 2Fe-2S iron-sulfur cluster binding domain K00245 - 1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 349.0
HFD2_k127_357772_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 337.0
HFD2_k127_357772_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 296.0
HFD2_k127_357772_8 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005918 297.0
HFD2_k127_357772_9 Fumarase C-terminus K01678,K03780 - 4.2.1.2,4.2.1.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001721 282.0
HFD2_k127_358407_0 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 348.0
HFD2_k127_358407_1 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000009101 121.0
HFD2_k127_358407_2 cytochrome C K08738 - - 0.0000000000000000000009207 98.0
HFD2_k127_3589147_0 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate K01612 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044464 4.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004964 333.0
HFD2_k127_3589147_1 ABC transporter substrate binding protein K01989 - - 0.0000001742 59.0
HFD2_k127_3605340_0 Dehydrogenase K00117 - 1.1.5.2 1.634e-276 866.0
HFD2_k127_3605340_1 Resolvase K06400 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 335.0
HFD2_k127_3605340_2 Resolvase K06400 - - 0.0000000000000000000000000002229 129.0
HFD2_k127_3605340_3 - - - - 0.0000000000000000001889 96.0
HFD2_k127_3605340_4 Transposase IS116/IS110/IS902 family - - - 0.00000000000000008033 84.0
HFD2_k127_3640789_0 Dehydrogenase K00114 - 1.1.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006204 437.0
HFD2_k127_3640789_1 Belongs to the hyi family K01816 - 5.3.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 334.0
HFD2_k127_364216_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 2.441e-268 839.0
HFD2_k127_364216_1 Major facilitator superfamily - - - 6.947e-267 829.0
HFD2_k127_364216_2 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001817 287.0
HFD2_k127_364216_3 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000005804 241.0
HFD2_k127_364216_4 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000812 208.0
HFD2_k127_364216_5 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141 - 0.0000000000000000000000000000000000000005495 150.0
HFD2_k127_364216_6 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.00000000000000000003645 91.0
HFD2_k127_364216_7 - - - - 0.00000001221 61.0
HFD2_k127_3691344_0 Aldehyde dehydrogenase family K04072,K15515 - 1.1.1.1,1.2.1.10,1.2.1.81 0.0 1223.0
HFD2_k127_3691344_1 Protein of unknown function (DUF1298) K00635 - 2.3.1.20 0.00000000000000003459 85.0
HFD2_k127_3718956_0 PLD-like domain - - - 2.525e-219 698.0
HFD2_k127_3718956_1 LVIVD repeat - - - 2.957e-215 676.0
HFD2_k127_3718956_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007753 454.0
HFD2_k127_3718956_3 Zinc-uptake complex component A periplasmic K02077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006715 375.0
HFD2_k127_3718956_4 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005301 353.0
HFD2_k127_3718956_5 phosphate-selective porin O and P - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 332.0
HFD2_k127_3718956_6 ABC-3 protein K02075 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006663 308.0
HFD2_k127_3718956_7 - - - - 0.0000000000000000000000003993 117.0
HFD2_k127_3749367_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0 1051.0
HFD2_k127_3749367_1 Proton-conducting membrane transporter - - - 1.882e-275 861.0
HFD2_k127_3749367_10 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002661 401.0
HFD2_k127_3749367_11 COG4237 Hydrogenase 4 membrane component (E) K12140 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004076 302.0
HFD2_k127_3749367_12 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 308.0
HFD2_k127_3749367_13 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003201 293.0
HFD2_k127_3749367_14 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000001968 233.0
HFD2_k127_3749367_15 [2Fe-2S] binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000003179 214.0
HFD2_k127_3749367_17 Flavin reductase like domain - - - 0.000000000000000000000000000000002144 135.0
HFD2_k127_3749367_18 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000003169 124.0
HFD2_k127_3749367_19 PFAM toluene tolerance family protein K07323 - - 0.00000000000000000002818 100.0
HFD2_k127_3749367_2 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483 - 1.14.14.9 1.676e-200 644.0
HFD2_k127_3749367_20 - - - - 0.000000000000000000292 94.0
HFD2_k127_3749367_21 Carbon monoxide dehydrogenase subunit G (CoxG) K09386 - - 0.00000000000002125 79.0
HFD2_k127_3749367_22 Metallo-beta-lactamase superfamily - - - 0.00000000000007289 79.0
HFD2_k127_3749367_3 PFAM General substrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 596.0
HFD2_k127_3749367_4 Sodium:dicarboxylate symporter family K11103 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 513.0
HFD2_k127_3749367_5 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 464.0
HFD2_k127_3749367_6 PFAM NADH Ubiquinone plastoquinone (complex I) K12141 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 447.0
HFD2_k127_3749367_7 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 431.0
HFD2_k127_3749367_8 NADH dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 418.0
HFD2_k127_3749367_9 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 401.0
HFD2_k127_376291_0 - - - - 2.935e-225 706.0
HFD2_k127_376291_1 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) - - - 0.0000000000000000000000000000000000000000000000000000115 204.0
HFD2_k127_376291_2 N-terminal half of MaoC dehydratase - - - 0.00000000000000000000000000000000000000000000000000001369 192.0
HFD2_k127_376291_3 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 0.00000000000000000000000000000000000000000000000000244 187.0
HFD2_k127_376291_4 MaoC like domain - - - 0.00000000000000000000000000000000000000000000000435 175.0
HFD2_k127_376291_5 Phasin protein - - - 0.000000000000000000000000001158 117.0
HFD2_k127_3766083_0 Conserved region in glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 2345.0
HFD2_k127_3766083_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000009838 87.0
HFD2_k127_3792705_0 PFAM Helicase conserved C-terminal domain K17675 - 3.6.4.13 2.943e-266 844.0
HFD2_k127_3792705_1 Cobalamin biosynthesis protein CobT VWA domain K09883 - 6.6.1.2 3.544e-240 757.0
HFD2_k127_3792705_10 Esterase-like activity of phytase - - - 0.00000000000000000000000000000000000000000000000000000000000000009987 238.0
HFD2_k127_3792705_11 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.0000000000000000000000000000000000000000000000000000000000002031 213.0
HFD2_k127_3792705_12 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000983 199.0
HFD2_k127_3792705_13 Belongs to the UPF0312 family K12262 - - 0.000000000000000000000000000000000000000000000000001008 199.0
HFD2_k127_3792705_14 LysE type translocator - - - 0.000000000000000000000000000000000000000002804 164.0
HFD2_k127_3792705_15 DnaJ molecular chaperone homology domain - - - 0.00000000000000000000000000000000000000001254 160.0
HFD2_k127_3792705_16 Peptidyl-prolyl cis-trans K03772 - 5.2.1.8 0.0000000000000000000000000000000000000008935 154.0
HFD2_k127_3792705_17 Belongs to the Nudix hydrolase family - - - 0.0000000000000000000000000000000000001908 145.0
HFD2_k127_3792705_18 YceI-like domain - - - 0.00000000000000000000000000000005811 139.0
HFD2_k127_3792705_19 YceI-like domain - - - 0.0000000000000000000000000000001246 132.0
HFD2_k127_3792705_2 Cobaltochelatase CobS subunit N terminal K09882 - 6.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000434 546.0
HFD2_k127_3792705_20 Usg-like family - - - 0.000000000000000000000000000001926 122.0
HFD2_k127_3792705_21 Ribosomal L28 family K02902 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000533 119.0
HFD2_k127_3792705_22 S4 RNA-binding domain K04762 - - 0.000000000000000000000000000815 114.0
HFD2_k127_3792705_23 Belongs to the BolA IbaG family K05527,K22066 - - 0.0000000000000000000000001516 108.0
HFD2_k127_3792705_24 Protein of unknown function (DUF3108) - - - 0.0000000000000000000008546 106.0
HFD2_k127_3792705_25 GntR family transcriptional regulator K15977 - - 0.00000000000000000003619 95.0
HFD2_k127_3792705_26 nuclease - - - 0.00000000000000002249 84.0
HFD2_k127_3792705_27 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides K01465 - 3.5.2.3 0.000000000000001175 77.0
HFD2_k127_3792705_28 Staphylococcal nuclease homologue - - - 0.0000000002795 68.0
HFD2_k127_3792705_3 COG0277 FAD FMN-containing dehydrogenases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009962 437.0
HFD2_k127_3792705_4 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 358.0
HFD2_k127_3792705_5 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003442 338.0
HFD2_k127_3792705_6 amidohydrolase K07045,K14333 - 4.1.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 315.0
HFD2_k127_3792705_7 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004267 280.0
HFD2_k127_3792705_8 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.000000000000000000000000000000000000000000000000000000000000000000006091 257.0
HFD2_k127_3792705_9 CarD-like/TRCF domain K07736 - - 0.00000000000000000000000000000000000000000000000000000000000000004115 231.0
HFD2_k127_3796813_0 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003984 371.0
HFD2_k127_3796813_1 Adenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 339.0
HFD2_k127_3796813_2 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 304.0
HFD2_k127_3796813_3 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004685 239.0
HFD2_k127_3796813_4 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000000000000000000004839 181.0
HFD2_k127_3796813_5 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000000000000000000000002252 173.0
HFD2_k127_3796813_6 - - - - 0.00000000000000000001642 98.0
HFD2_k127_3796813_7 DoxX-like family - - - 0.000000003092 66.0
HFD2_k127_3813683_0 Adenylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 491.0
HFD2_k127_3813683_1 Alpha/beta hydrolase family K00641 - 2.3.1.31 0.0000000000000000000000000000000000000000000000000000543 194.0
HFD2_k127_3813683_2 PBP superfamily domain K05772 - - 0.0000000000000000000000000000000000000000000000000008135 195.0
HFD2_k127_3813683_3 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000001144 111.0
HFD2_k127_382886_0 Class II Aldolase and Adducin N-terminal domain - - - 2.12e-311 968.0
HFD2_k127_382886_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 527.0
HFD2_k127_382886_10 Cytochrome C oxidase, cbb3-type, subunit III K08738 - - 0.00000000000000000000000000000000000000000000000001637 186.0
HFD2_k127_382886_11 MaoC like domain - - - 0.000000000000000000000000000000000000000003296 165.0
HFD2_k127_382886_12 dehydratase - - - 0.00000000000000000000000000000000000000001105 160.0
HFD2_k127_382886_13 Protein of unknown function (DUF1761) - - - 0.0000000000000000000000000000000000004707 144.0
HFD2_k127_382886_14 GYD domain - - - 0.00000000000000000000000000019 120.0
HFD2_k127_382886_15 - - - - 0.000000000000000000000001553 115.0
HFD2_k127_382886_16 - - - - 0.000000000000003413 82.0
HFD2_k127_382886_17 PIN domain - - - 0.0000000004439 66.0
HFD2_k127_382886_2 Mo-co oxidoreductase dimerisation domain K17225 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 515.0
HFD2_k127_382886_3 Initiation factor 2 subunit family K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008737 499.0
HFD2_k127_382886_4 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003277 466.0
HFD2_k127_382886_5 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000001979 258.0
HFD2_k127_382886_6 permease - - - 0.0000000000000000000000000000000000000000000000000000000000000186 228.0
HFD2_k127_382886_7 Multi-copper polyphenol oxidoreductase laccase K05810 - - 0.00000000000000000000000000000000000000000000000000000000001342 210.0
HFD2_k127_382886_8 - - - - 0.00000000000000000000000000000000000000000000000000000001067 203.0
HFD2_k127_382886_9 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000000000314 200.0
HFD2_k127_3855961_0 N-methylhydantoinase A acetone carboxylase, beta subunit K01473 - 3.5.2.14 2.358e-318 987.0
HFD2_k127_3855961_1 N-methylhydantoinase B acetone carboxylase alpha subunit K01474 - 3.5.2.14 1.805e-279 885.0
HFD2_k127_3855961_10 Cytochrome C oxidase, mono-heme subunit/FixO K00405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008895 261.0
HFD2_k127_3855961_11 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.00000000000000000000000000000000000000000000000000000000000000004444 234.0
HFD2_k127_3855961_12 Binding-protein-dependent transport system inner membrane component K02050,K15554 - - 0.00000000000000000000000000000000000000000000000000002291 198.0
HFD2_k127_3855961_13 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000004515 201.0
HFD2_k127_3855961_14 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000001316 184.0
HFD2_k127_3855961_15 Methyltransferase domain - - - 0.0000000000000000000000000000000000000002256 159.0
HFD2_k127_3855961_16 Cupin domain - - - 0.0000000000000000000000000000000000000005926 154.0
HFD2_k127_3855961_17 - - - - 0.0000000000000000000000000003918 126.0
HFD2_k127_3855961_18 Creatinase/Prolidase N-terminal domain - - - 0.0000000000000000000000008447 106.0
HFD2_k127_3855961_19 Yip1 domain - - - 0.0000000000000000002901 95.0
HFD2_k127_3855961_2 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000035 610.0
HFD2_k127_3855961_20 NMT1/THI5 like K02051 - - 0.00001598 56.0
HFD2_k127_3855961_21 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.00003918 55.0
HFD2_k127_3855961_3 SMP-30/Gluconolaconase/LRE-like region K14274 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 477.0
HFD2_k127_3855961_4 DEAD-like helicases superfamily K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 473.0
HFD2_k127_3855961_5 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009051 376.0
HFD2_k127_3855961_7 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 310.0
HFD2_k127_3855961_8 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 303.0
HFD2_k127_3855961_9 Major facilitator superfamily K05548,K05819,K08195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000381 300.0
HFD2_k127_3863871_0 beta-galactosidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000369 551.0
HFD2_k127_3876962_0 AcrB/AcrD/AcrF family - - - 0.0 1193.0
HFD2_k127_3876962_1 Transglycosylase - - - 3.941e-307 972.0
HFD2_k127_3876962_10 COG1544 Ribosome-associated protein Y (PSrp-1) - - - 0.000000000000000000000000000000000000000000000000000000000001089 215.0
HFD2_k127_3876962_11 metal-dependent hydrolase with the TIM-barrel fold - - - 0.000000000000000000000000000000000000000000000009072 190.0
HFD2_k127_3876962_13 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000605 137.0
HFD2_k127_3876962_14 beta-lactamase domain protein K05555 - - 0.0000000000000000000000000000000005385 143.0
HFD2_k127_3876962_15 - - - - 0.000000000000000000000000003666 122.0
HFD2_k127_3876962_16 - - - - 0.0000000000000000000000006455 115.0
HFD2_k127_3876962_17 - - - - 0.0000000000000000000008368 106.0
HFD2_k127_3876962_18 - - - - 0.0000000000000000007252 97.0
HFD2_k127_3876962_19 - - - - 0.0000000000007996 77.0
HFD2_k127_3876962_2 PQQ enzyme repeat K00114 - 1.1.2.8 2.423e-233 736.0
HFD2_k127_3876962_20 Domain of unknown function (DUF4440) - - - 0.00000001241 65.0
HFD2_k127_3876962_21 Major Facilitator Superfamily - - - 0.0000004618 53.0
HFD2_k127_3876962_3 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006587 622.0
HFD2_k127_3876962_4 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 521.0
HFD2_k127_3876962_5 Surface antigen K07278 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003495 515.0
HFD2_k127_3876962_6 succinate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009766 399.0
HFD2_k127_3876962_7 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002774 301.0
HFD2_k127_3876962_8 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K16079 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008366 270.0
HFD2_k127_3876962_9 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000003817 249.0
HFD2_k127_3884321_0 GMC oxidoreductase - - - 5.41e-284 886.0
HFD2_k127_3884321_1 GMC oxidoreductase - - - 4.29e-245 769.0
HFD2_k127_3884321_10 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.00000000000000000000000000000000000000000000000000002833 199.0
HFD2_k127_3884321_11 helix_turn_helix, mercury resistance K13638 - - 0.00000000000000000000000000000000000000000000000000003692 191.0
HFD2_k127_3884321_12 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000009808 172.0
HFD2_k127_3884321_13 Cytochrome c K08738 - - 0.00000000000000000000000000000000000000002605 155.0
HFD2_k127_3884321_14 Phage derived protein Gp49-like (DUF891) - - - 0.0000000000000000000000000000008343 124.0
HFD2_k127_3884321_15 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000001438 123.0
HFD2_k127_3884321_16 metal-dependent hydrolase with the TIM-barrel fold - - - 0.00000000000000000000000000000394 133.0
HFD2_k127_3884321_17 Thioredoxin domain - - - 0.000000000000000000000008154 108.0
HFD2_k127_3884321_18 Helix-turn-helix domain - - - 0.000000000000000007363 87.0
HFD2_k127_3884321_19 methyltransferase - - - 0.000000000000000008231 84.0
HFD2_k127_3884321_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009555 565.0
HFD2_k127_3884321_3 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 331.0
HFD2_k127_3884321_4 Gluconate 2-dehydrogenase subunit 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009942 285.0
HFD2_k127_3884321_5 Gluconate 2-dehydrogenase subunit 3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008208 271.0
HFD2_k127_3884321_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001324 233.0
HFD2_k127_3884321_7 PFAM Coenzyme A transferase K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000003593 228.0
HFD2_k127_3884321_8 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000001228 218.0
HFD2_k127_3884321_9 Coenzyme A transferase K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000005868 207.0
HFD2_k127_3898705_0 amidase activity K01426 - 3.5.1.4 3.449e-237 753.0
HFD2_k127_3898705_1 Alpha/beta hydrolase family K01561 - 3.8.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000168 274.0
HFD2_k127_3898705_2 Protein of unknown function (DUF2726) - - - 0.000000000000000000000000000000000000000000003555 170.0
HFD2_k127_3898705_3 Bacterial extracellular solute-binding protein K02020,K22003 - 5.3.3.7 0.0000000000000000000000000000000000000000004205 167.0
HFD2_k127_3898705_4 - - - - 0.00000000000000000000007838 110.0
HFD2_k127_3898705_5 - - - - 0.0000000000000000000473 104.0
HFD2_k127_3898705_6 - - - - 0.00000000000000001594 93.0
HFD2_k127_3898705_7 Cytochrome c - - - 0.00000000001207 69.0
HFD2_k127_3905262_0 Metal binding domain of Ada K00567,K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006428 482.0
HFD2_k127_3905262_1 HupE / UreJ protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 289.0
HFD2_k127_3905262_10 Heavy-metal resistance - - - 0.000000000000000000002649 99.0
HFD2_k127_3905262_11 nitrate reductase molybdenum cofactor assembly chaperone K00373 - - 0.000000000000000000006024 96.0
HFD2_k127_3905262_12 - - - - 0.00000000000000002028 88.0
HFD2_k127_3905262_13 - - - - 0.000000000000001338 90.0
HFD2_k127_3905262_14 - - - - 0.000000000003643 79.0
HFD2_k127_3905262_15 - - - - 0.00000005475 61.0
HFD2_k127_3905262_2 - - - - 0.000000000000000000000000000000000000000000000000000000000001034 216.0
HFD2_k127_3905262_3 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000000000000000001007 176.0
HFD2_k127_3905262_4 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.00000000000000000000000000000000000000002383 164.0
HFD2_k127_3905262_5 - - - - 0.000000000000000000000000000000003426 134.0
HFD2_k127_3905262_6 - - - - 0.000000000000000000000000002002 122.0
HFD2_k127_3905262_7 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000001074 114.0
HFD2_k127_3905262_8 - - - - 0.0000000000000000000000002227 117.0
HFD2_k127_3905262_9 - - - - 0.00000000000000000000002633 106.0
HFD2_k127_3911745_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1416.0
HFD2_k127_3911745_1 - - - - 1.134e-276 867.0
HFD2_k127_3911745_10 Aldehyde dehydrogenase family K00138,K09472,K12254 - 1.2.1.54,1.2.1.99 2.013e-217 685.0
HFD2_k127_3911745_11 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 3.648e-199 628.0
HFD2_k127_3911745_12 O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 608.0
HFD2_k127_3911745_13 HlyD membrane-fusion protein of T1SS K16300 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 592.0
HFD2_k127_3911745_14 O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003291 595.0
HFD2_k127_3911745_15 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 554.0
HFD2_k127_3911745_16 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007363 557.0
HFD2_k127_3911745_17 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377,K16554 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 427.0
HFD2_k127_3911745_18 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 400.0
HFD2_k127_3911745_19 Histidine kinase-like ATPases K14980 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004594 383.0
HFD2_k127_3911745_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 3.564e-272 854.0
HFD2_k127_3911745_20 Nucleotidyl transferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 364.0
HFD2_k127_3911745_21 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000832 357.0
HFD2_k127_3911745_22 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004977 340.0
HFD2_k127_3911745_23 PFAM membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 337.0
HFD2_k127_3911745_24 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 351.0
HFD2_k127_3911745_25 Transcriptional regulatory protein, C terminal K14981 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 301.0
HFD2_k127_3911745_26 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004779 290.0
HFD2_k127_3911745_27 Outer membrane efflux protein K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001742 280.0
HFD2_k127_3911745_28 Calcineurin-like phosphoesterase K07313 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000008235 239.0
HFD2_k127_3911745_29 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000000000001471 208.0
HFD2_k127_3911745_3 - - - - 9.791e-271 850.0
HFD2_k127_3911745_30 Glycosyltransferase family 10 (fucosyltransferase) C-term - - - 0.0000000000000000000000000000000000000000003438 171.0
HFD2_k127_3911745_31 Sel1 domain protein repeat-containing protein K07126 - - 0.00000000000000000000000000000007296 138.0
HFD2_k127_3911745_32 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.00000000000000000000000000001366 130.0
HFD2_k127_3911745_33 Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain K08738 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005758,GO:0006091,GO:0006119,GO:0006122,GO:0006123,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0017144,GO:0019637,GO:0019646,GO:0019693,GO:0019866,GO:0022900,GO:0022904,GO:0031090,GO:0031966,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0034641,GO:0042773,GO:0042775,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045155,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0070013,GO:0070469,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 - 0.00000000000000000000000002018 115.0
HFD2_k127_3911745_34 Bacterial transglutaminase-like cysteine proteinase BTLCP - - - 0.000000000000000000000000176 118.0
HFD2_k127_3911745_35 Belongs to the bacterial ribosomal protein bL33 family K02913 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000003287 99.0
HFD2_k127_3911745_36 Flavinator of succinate dehydrogenase K09159 - - 0.00000000000000001191 85.0
HFD2_k127_3911745_37 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000000000005239 86.0
HFD2_k127_3911745_38 - - - - 0.00000000000432 70.0
HFD2_k127_3911745_39 - - - - 0.000001071 58.0
HFD2_k127_3911745_4 - - - - 7.147e-269 845.0
HFD2_k127_3911745_40 Sporulation related domain - - - 0.000004699 58.0
HFD2_k127_3911745_41 - - - - 0.000009117 57.0
HFD2_k127_3911745_42 PFAM type IV pilus assembly PilZ - - - 0.00008193 51.0
HFD2_k127_3911745_5 - - - - 1.864e-267 842.0
HFD2_k127_3911745_6 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 5.878e-261 821.0
HFD2_k127_3911745_7 ATPases associated with a variety of cellular activities K06148,K16299 - - 4.735e-255 797.0
HFD2_k127_3911745_8 - - - - 7.161e-249 789.0
HFD2_k127_3911745_9 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 GO:0000175,GO:0003674,GO:0003724,GO:0003824,GO:0004386,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008408,GO:0008997,GO:0009056,GO:0009057,GO:0009266,GO:0009409,GO:0009628,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016896,GO:0017111,GO:0019222,GO:0019439,GO:0034458,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 1.634e-245 785.0
HFD2_k127_3948122_0 PFAM GTP cyclohydrolase I Nitrile oxidoreductase K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000001292 243.0
HFD2_k127_3948122_1 Beta-lactamase superfamily domain - - - 0.0000000000000000000000004908 107.0
HFD2_k127_3948122_2 dihydropteroate synthase K00796 - 2.5.1.15 0.00000000000000000000000135 110.0
HFD2_k127_3969060_0 PhoD-like phosphatase, N-terminal domain K01113 - 3.1.3.1 5.145e-196 620.0
HFD2_k127_3969060_1 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0000000000000000000000000000000000000000000000000000002958 201.0
HFD2_k127_3969060_2 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000001065 136.0
HFD2_k127_3969060_3 - - - - 0.000000000000000000000002114 115.0
HFD2_k127_3975390_0 COG1042 Acyl-CoA synthetase (NDP forming) K09181 GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006475,GO:0006807,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019538,GO:0022607,GO:0032459,GO:0032462,GO:0034212,GO:0036211,GO:0043170,GO:0043254,GO:0043412,GO:0043543,GO:0043933,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052858,GO:0061733,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 348.0
HFD2_k127_3975390_1 COG2518 Protein-L-isoaspartate carboxylmethyltransferase K00573 - 2.1.1.77 0.00000000000000000000594 95.0
HFD2_k127_3975390_2 - - - - 0.00000000000000001522 86.0
HFD2_k127_3995232_0 Penicillin amidase K01434 - 3.5.1.11 1.156e-243 774.0
HFD2_k127_3995232_1 Adenylate cyclase - - - 1.036e-235 738.0
HFD2_k127_3995232_10 xylanase chitin deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001023 277.0
HFD2_k127_3995232_11 glutaminyl-tRNA synthetase K01886 - 6.1.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001047 270.0
HFD2_k127_3995232_12 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006034 261.0
HFD2_k127_3995232_13 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002242 253.0
HFD2_k127_3995232_14 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000006287 225.0
HFD2_k127_3995232_15 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000002681 221.0
HFD2_k127_3995232_16 Protein of unknown function (DUF418) K07148 - - 0.00000000000000000000000000000000000000000000000000008949 199.0
HFD2_k127_3995232_17 Protein of unknown function (DUF418) K07148 - - 0.00000000000000000000000000000000000000000002053 168.0
HFD2_k127_3995232_18 Peptidase dimerisation domain - - - 0.0000000000000000000000000000001634 127.0
HFD2_k127_3995232_19 Endoribonuclease L-PSP - - - 0.000000000000000000000000004955 115.0
HFD2_k127_3995232_2 Aldehyde dehydrogenase family K00128,K00146 - 1.2.1.3,1.2.1.39 1.601e-213 676.0
HFD2_k127_3995232_20 - - - - 0.000000000000000000000003114 114.0
HFD2_k127_3995232_21 Adenylate cyclase - - - 0.000000000000000000000141 106.0
HFD2_k127_3995232_22 Adenylate cyclase - - - 0.000008518 51.0
HFD2_k127_3995232_3 GH3 auxin-responsive promoter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 575.0
HFD2_k127_3995232_4 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 565.0
HFD2_k127_3995232_5 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 479.0
HFD2_k127_3995232_6 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 394.0
HFD2_k127_3995232_7 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 388.0
HFD2_k127_3995232_8 PFAM aldo keto reductase - GO:0003674,GO:0003824,GO:0006081,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016491,GO:0042180,GO:0042182,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0051596,GO:0055114,GO:0071704,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 314.0
HFD2_k127_3995232_9 Adenylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 318.0
HFD2_k127_4015054_0 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 459.0
HFD2_k127_4015054_1 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004608 434.0
HFD2_k127_4015054_10 Has a post-transcriptional repressor function in flagellum biogenesis. Associates with the 5'-UTR of fljK K06601 - - 0.00000000000000000000000000000000000000000000000002122 183.0
HFD2_k127_4015054_11 transcriptional - - - 0.000000000000000000000000000000000000000000002005 168.0
HFD2_k127_4015054_12 Phosphoribosyl-ATP K01523 - 3.6.1.31 0.00000000000000000000000000000000131 132.0
HFD2_k127_4015054_13 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000003122 123.0
HFD2_k127_4015054_14 Flagellar protein FlaF K06602 - - 0.00000000000000000000000002838 111.0
HFD2_k127_4015054_2 TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 415.0
HFD2_k127_4015054_3 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004669 406.0
HFD2_k127_4015054_4 Belongs to the class-I aminoacyl-tRNA synthetase family K01894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007285 369.0
HFD2_k127_4015054_5 COG1702 Phosphate starvation-inducible protein PhoH K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008949 350.0
HFD2_k127_4015054_6 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008967 316.0
HFD2_k127_4015054_7 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005093 320.0
HFD2_k127_4015054_8 Transporter associated domain K06189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 293.0
HFD2_k127_4015054_9 Phospholipase/Carboxylesterase K06999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001982 257.0
HFD2_k127_4063569_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1472.0
HFD2_k127_4063569_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009691 433.0
HFD2_k127_4063569_2 Protein of unknown function (DUF1194) - - - 0.00000000000000000000000000000000000000000000000000009388 197.0
HFD2_k127_4063569_3 Subtilase family - - - 0.000000000000000000000000000000000000000000000000005122 199.0
HFD2_k127_4063569_4 Macrocin-O-methyltransferase (TylF) - - - 0.00000000000000000000000000000000000000000000000001173 188.0
HFD2_k127_4063569_5 Protein of unknown function (DUF1465) K13592 - - 0.00000000000000000000000000000000002562 138.0
HFD2_k127_4063569_6 Binds the 23S rRNA K02909 - - 0.000000000000000000000000000114 117.0
HFD2_k127_4063569_7 response to cobalt ion - - - 0.000000000000000000001395 101.0
HFD2_k127_4063569_8 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000006656 78.0
HFD2_k127_4112071_0 Stage II sporulation K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000103 206.0
HFD2_k127_4112071_1 SMART protein phosphatase 2C domain protein - - - 0.00000000000000000000000007576 120.0
HFD2_k127_4116743_0 ATPase (P-type) K01535 - 3.6.3.6 0.0 1210.0
HFD2_k127_4116743_1 Integrase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001446 254.0
HFD2_k127_4116743_2 Cyclic nucleotide-binding domain K21563 - - 0.0000000000000000000000000000000000000000000000000000000104 205.0
HFD2_k127_4116743_3 - - - - 0.00000000000000000000000000000000000000000000000000007453 195.0
HFD2_k127_4116743_4 Molybdate transporter of MFS superfamily - - - 0.000002504 56.0
HFD2_k127_4183214_0 Dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008588 598.0
HFD2_k127_4183214_1 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 582.0
HFD2_k127_4183214_11 RelE toxin of RelE / RelB toxin-antitoxin system - - - 0.0000000000000000000000000000001497 127.0
HFD2_k127_4183214_12 transcriptional regulator, XRE family K07726 - - 0.0000000000000000000000000000002815 125.0
HFD2_k127_4183214_13 - - - - 0.000000000008953 77.0
HFD2_k127_4183214_14 COG2335, Secreted and surface protein containing fasciclin-like repeats - - - 0.00000001536 63.0
HFD2_k127_4183214_2 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 457.0
HFD2_k127_4183214_3 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 353.0
HFD2_k127_4183214_4 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004165 296.0
HFD2_k127_4183214_5 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000103 271.0
HFD2_k127_4183214_6 PFAM SMP-30 Gluconolaconase LRE domain protein K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000002135 256.0
HFD2_k127_4183214_7 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000000000000000003299 219.0
HFD2_k127_4183214_8 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000000009755 174.0
HFD2_k127_4183214_9 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000006971 159.0
HFD2_k127_4208056_0 Glutaminyl-tRNA synthetase K01886 - 6.1.1.18 5.292e-262 812.0
HFD2_k127_4208056_1 Pyridine nucleotide-disulphide oxidoreductase K07222 - - 4.993e-198 623.0
HFD2_k127_4208056_10 Cupin - - - 0.000000177 58.0
HFD2_k127_4208056_11 response regulator - - - 0.0000003761 55.0
HFD2_k127_4208056_12 Enoyl-(Acyl carrier protein) reductase - - - 0.00003922 47.0
HFD2_k127_4208056_2 FAD binding domain K00480 - 1.14.13.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 497.0
HFD2_k127_4208056_3 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 498.0
HFD2_k127_4208056_4 OsmC-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003332 309.0
HFD2_k127_4208056_5 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009679 272.0
HFD2_k127_4208056_6 Protein of unknown function (DUF1428) - - - 0.000000000000000000000000000000000000000000000000000001944 193.0
HFD2_k127_4208056_7 Protein of unknown function (DUF1194) - - - 0.000000000000000000000000000000000000000000000000001315 197.0
HFD2_k127_4208056_9 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000001914 116.0
HFD2_k127_42331_0 AMP-binding enzyme C-terminal domain K00666,K02182 - 6.2.1.48 9.868e-253 804.0
HFD2_k127_42331_1 NAD(P)H quinone oxidoreductase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005129 369.0
HFD2_k127_42331_2 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004372 331.0
HFD2_k127_42331_3 Protein of unknown function (DUF1013) K09987 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001765 270.0
HFD2_k127_42331_4 DedA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000004238 237.0
HFD2_k127_42331_5 Regulator of CtrA degradation K13592 - - 0.00001983 49.0
HFD2_k127_42331_6 Protein of unknown function (DUF1192) - - - 0.0002299 47.0
HFD2_k127_4238389_0 Glycosyl transferase family 41 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 484.0
HFD2_k127_4238389_1 Glycosyl transferase family 41 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000336 441.0
HFD2_k127_4275969_0 Spermine/spermidine synthase domain - - - 8.746e-287 909.0
HFD2_k127_4275969_1 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 445.0
HFD2_k127_4275969_11 UPF0391 membrane protein - - - 0.0000000000001138 72.0
HFD2_k127_4275969_12 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000001306 65.0
HFD2_k127_4275969_13 DNA polymerase III - - - 0.0000000393 58.0
HFD2_k127_4275969_14 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000004596 63.0
HFD2_k127_4275969_15 Iron-containing redox enzyme K06137 - 1.3.3.11 0.000002668 59.0
HFD2_k127_4275969_2 NAD(P)-binding Rossmann-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 377.0
HFD2_k127_4275969_3 Sugar (and other) transporter K08195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 301.0
HFD2_k127_4275969_4 transduction histidine kinase K07716 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000002867 272.0
HFD2_k127_4275969_5 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000005957 155.0
HFD2_k127_4275969_6 HWE histidine kinase - - - 0.0000000000000000000000000000000002393 141.0
HFD2_k127_4275969_7 - - - - 0.000000000000000000000000009401 121.0
HFD2_k127_4275969_8 - - - - 0.00000000000000000000000001815 114.0
HFD2_k127_4275969_9 - - - - 0.0000000000000103 79.0
HFD2_k127_4279272_0 PFAM amidohydrolase 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 409.0
HFD2_k127_4279272_1 - - - - 0.0000000000000002083 87.0
HFD2_k127_4279272_2 Amidohydrolase family - - - 0.000000000002132 74.0
HFD2_k127_4300085_0 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 398.0
HFD2_k127_4300085_1 ABC transporter, phosphonate, periplasmic substrate-binding protein K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003884 257.0
HFD2_k127_4300085_2 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000004807 120.0
HFD2_k127_4307477_0 Epoxide hydrolase N terminus - - - 6.092e-195 614.0
HFD2_k127_4307477_1 Major Facilitator Superfamily K08169 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004584 485.0
HFD2_k127_4307477_2 Transposase domain (DUF772) - - - 0.00000000000000000000000000000001924 128.0
HFD2_k127_4307477_3 Alpha/beta hydrolase family - - - 0.000000000000005897 76.0
HFD2_k127_4307477_4 NTF2 fold immunity protein - - - 0.00004045 52.0
HFD2_k127_4333943_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1165.0
HFD2_k127_4333943_1 Endothelin-converting enzyme K09610 GO:0003008,GO:0003016,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0007154,GO:0007165,GO:0007186,GO:0007218,GO:0007585,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0023052,GO:0031224,GO:0031226,GO:0032501,GO:0043170,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 - 4.188e-210 679.0
HFD2_k127_4333943_10 Lipopolysaccharide-assembly K03643 - - 0.000000000000007433 81.0
HFD2_k127_4333943_11 - - - - 0.000000000839 68.0
HFD2_k127_4333943_12 Invasion associated locus B (IalB) protein - - - 0.0000002687 61.0
HFD2_k127_4333943_2 Histidine biosynthesis protein K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 381.0
HFD2_k127_4333943_3 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 293.0
HFD2_k127_4333943_4 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000000000000003441 242.0
HFD2_k127_4333943_5 PilZ domain - - - 0.0000000000000000000000000000000000004862 150.0
HFD2_k127_4333943_6 Rhomboid family - - - 0.000000000000000000000000000000000002939 147.0
HFD2_k127_4333943_7 PFAM Outer membrane efflux protein - - - 0.00000000000000000000000000000000000409 142.0
HFD2_k127_4333943_8 PAS domain - - - 0.00000000000000000327 95.0
HFD2_k127_4333943_9 Invasion associated locus B (IalB) protein - - - 0.0000000000000000782 89.0
HFD2_k127_4347999_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1045.0
HFD2_k127_4347999_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1020.0
HFD2_k127_4347999_10 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000276 272.0
HFD2_k127_4347999_11 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000002525 215.0
HFD2_k127_4347999_12 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.00000000000000000000000000000000000000000000001197 173.0
HFD2_k127_4347999_13 fumarate reductase flavoprotein subunit - - - 0.000000000000000000000000000000000000007254 153.0
HFD2_k127_4347999_14 Domain of unknown function (DUF1476) - - - 0.000000000000000000000000000000005722 132.0
HFD2_k127_4347999_15 Dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000000001143 130.0
HFD2_k127_4347999_16 Belongs to the BolA IbaG family - - - 0.00000000000000000000000000002707 119.0
HFD2_k127_4347999_17 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000001675 113.0
HFD2_k127_4347999_18 PFAM Carbohydrate-selective porin OprB - - - 0.000000000000000000000002109 118.0
HFD2_k127_4347999_19 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000001697 114.0
HFD2_k127_4347999_2 Belongs to the isocitrate and isopropylmalate dehydrogenases family K00031 - 1.1.1.42 1.793e-225 702.0
HFD2_k127_4347999_3 TonB dependent receptor - - - 8.141e-194 630.0
HFD2_k127_4347999_4 copper resistance - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 474.0
HFD2_k127_4347999_5 MmgE/PrpD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006299 447.0
HFD2_k127_4347999_6 SAICAR synthetase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 433.0
HFD2_k127_4347999_7 Ornithine cyclodeaminase/mu-crystallin family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 331.0
HFD2_k127_4347999_8 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000585 318.0
HFD2_k127_4347999_9 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 307.0
HFD2_k127_4357132_0 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005769 387.0
HFD2_k127_4357132_1 Cold shock protein domain K03704 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 332.0
HFD2_k127_4357132_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 GO:0003674,GO:0003824,GO:0004462,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016846,GO:0034641,GO:0043603,GO:0044237,GO:0051186,GO:0071704,GO:1901564 4.4.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000922 247.0
HFD2_k127_4357132_3 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000000000000000000000000000000000001135 197.0
HFD2_k127_4401356_0 Dehydrogenase K00117 - 1.1.5.2 3.34e-288 899.0
HFD2_k127_4401356_1 NAD-dependent K08678 - 4.1.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003719 541.0
HFD2_k127_4401356_2 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 342.0
HFD2_k127_4401356_3 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002773 298.0
HFD2_k127_4401356_4 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000001205 213.0
HFD2_k127_4401356_5 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000002599 210.0
HFD2_k127_4401356_6 Bacterial transglutaminase-like cysteine proteinase BTLCP - - - 0.000000000000000000000000000000000000006109 153.0
HFD2_k127_4410278_0 SMART Elongator protein 3 MiaB NifB K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 564.0
HFD2_k127_4410278_1 Thioesterase K01075 - 3.1.2.23 0.000000000000000000000000000000000000000000000000000001314 195.0
HFD2_k127_4410278_2 - - - - 0.0000000000000000000000000000000000000000000000000004697 186.0
HFD2_k127_4410278_3 protein conserved in bacteria - - - 0.00000000000000000000000000000001791 132.0
HFD2_k127_4410278_4 Amidohydrolase K03392 - 4.1.1.45 0.00000000000000009918 85.0
HFD2_k127_4426148_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 1.979e-238 758.0
HFD2_k127_4426148_1 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 314.0
HFD2_k127_4426148_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0044237,GO:0071704,GO:1901135 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 296.0
HFD2_k127_4432617_0 Pfam Cupin K00450,K11948 - 1.13.11.38,1.13.11.4 0.00000000000000000000000000000000000000000000000000000000000000000000000001466 264.0
HFD2_k127_4432617_1 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000178 193.0
HFD2_k127_4432617_2 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000001826 135.0
HFD2_k127_4457796_0 - - - - 0.0 1097.0
HFD2_k127_4457796_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 6.625e-268 836.0
HFD2_k127_4457796_10 [2Fe-2S] binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000372 216.0
HFD2_k127_4457796_11 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000002642 211.0
HFD2_k127_4457796_12 Trypsin - - - 0.000000000000000000000000000000000000000000000000000000234 207.0
HFD2_k127_4457796_13 lactoylglutathione lyase activity K01759 - 4.4.1.5 0.00000000000000000000000000003925 132.0
HFD2_k127_4457796_14 - - - - 0.00000000000000000000107 106.0
HFD2_k127_4457796_15 Asp/Glu/Hydantoin racemase - - - 0.00000000000000000004985 94.0
HFD2_k127_4457796_16 Cupin 2, conserved barrel domain protein - - - 0.000000000000003418 83.0
HFD2_k127_4457796_17 Domain of unknown function (DUF4115) K15539 - - 0.0000000000001136 82.0
HFD2_k127_4457796_19 Asp/Glu/Hydantoin racemase - - - 0.000000248 53.0
HFD2_k127_4457796_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 8.741e-238 758.0
HFD2_k127_4457796_3 Belongs to the heme-copper respiratory oxidase family K04561 - 1.7.2.5 1.063e-200 636.0
HFD2_k127_4457796_4 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 547.0
HFD2_k127_4457796_5 PQQ-like domain K05889 - 1.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 519.0
HFD2_k127_4457796_6 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000529 505.0
HFD2_k127_4457796_7 PFAM LysR substrate-binding protein, regulatory protein LysR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006447 316.0
HFD2_k127_4457796_8 Cytochrome c K02305 - - 0.0000000000000000000000000000000000000000000000000000000000000000001175 236.0
HFD2_k127_4457796_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000002223 238.0
HFD2_k127_449224_0 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 1.629e-214 674.0
HFD2_k127_449224_1 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 510.0
HFD2_k127_449224_2 Aldo/keto reductase family K05275 - 1.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 506.0
HFD2_k127_449224_3 Phosphoenolpyruvate phosphomutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000005904 249.0
HFD2_k127_449224_4 CAAX protease self-immunity K07052 - - 0.0000002981 59.0
HFD2_k127_4535881_0 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 534.0
HFD2_k127_4535881_1 PQQ-like domain K00114 - 1.1.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009268 535.0
HFD2_k127_4535881_10 - - - - 0.00000000000000000003011 100.0
HFD2_k127_4535881_11 NIPSNAP - - - 0.00000000000000001043 89.0
HFD2_k127_4535881_12 - - - - 0.00000000000000116 79.0
HFD2_k127_4535881_13 Alpha beta hydrolase - - - 0.0000000000002465 80.0
HFD2_k127_4535881_14 deoxyhypusine monooxygenase activity - - - 0.00002879 53.0
HFD2_k127_4535881_15 - - - - 0.0002948 47.0
HFD2_k127_4535881_2 HupE / UreJ protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 421.0
HFD2_k127_4535881_3 Mo-co oxidoreductase dimerisation domain K17225 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 345.0
HFD2_k127_4535881_4 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001194 283.0
HFD2_k127_4535881_5 Cytochrome C oxidase, cbb3-type, subunit III K08738 - - 0.0000000000000000000000000000000000001252 149.0
HFD2_k127_4535881_6 cytochrome - - - 0.000000000000000000000000001607 119.0
HFD2_k127_4535881_7 - - - - 0.00000000000000000000000000728 121.0
HFD2_k127_4535881_8 40-residue YVTN family beta-propeller repeat protein - - - 0.000000000000000000000003995 116.0
HFD2_k127_4535881_9 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000243 103.0
HFD2_k127_453852_0 Serine hydrolase involved in the detoxification of formaldehyde K01070 - 3.1.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008577 406.0
HFD2_k127_453852_1 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005222 363.0
HFD2_k127_453852_2 - - - - 0.00000000000000000000000000000000000000000000000000000000145 203.0
HFD2_k127_4547472_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 0.000000000000000000000000000000000000000000006766 166.0
HFD2_k127_4547472_1 Protein of unknown function (DUF499) - - - 0.00000000000000000000000000002664 135.0
HFD2_k127_4547472_2 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000001741 93.0
HFD2_k127_4547472_3 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.000000000000000001566 86.0
HFD2_k127_4586962_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1470.0
HFD2_k127_4586962_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1195.0
HFD2_k127_4586962_10 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 508.0
HFD2_k127_4586962_11 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038,K21977 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008764 510.0
HFD2_k127_4586962_12 Carbohydrate family 9 binding domain-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 527.0
HFD2_k127_4586962_13 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 497.0
HFD2_k127_4586962_14 MmgE/PrpD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 493.0
HFD2_k127_4586962_15 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004877 494.0
HFD2_k127_4586962_16 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007147 454.0
HFD2_k127_4586962_17 Glutamine synthetase, catalytic domain K01915 GO:0003674,GO:0003824,GO:0006576,GO:0006595,GO:0006598,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009308,GO:0009310,GO:0009445,GO:0009447,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0034024,GO:0034641,GO:0042402,GO:0044106,GO:0044237,GO:0071704,GO:0097164,GO:1901564,GO:1901565,GO:1901575 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 451.0
HFD2_k127_4586962_18 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004618 446.0
HFD2_k127_4586962_19 Major Facilitator Superfamily K13021 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000468 433.0
HFD2_k127_4586962_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 6.868e-264 823.0
HFD2_k127_4586962_20 Binding-protein-dependent transport system inner membrane component K15581 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 412.0
HFD2_k127_4586962_21 PFAM Enoyl-CoA hydratase isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007739 380.0
HFD2_k127_4586962_22 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034,K15582 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 389.0
HFD2_k127_4586962_23 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 388.0
HFD2_k127_4586962_24 Iron deficiency-induced protein A K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 367.0
HFD2_k127_4586962_25 PFAM General substrate transporter K08195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 369.0
HFD2_k127_4586962_26 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006404 364.0
HFD2_k127_4586962_27 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004829 352.0
HFD2_k127_4586962_28 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 338.0
HFD2_k127_4586962_29 AsmA-like C-terminal region K07289 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 339.0
HFD2_k127_4586962_3 Choline dehydrogenase and related flavoproteins K06151 - 1.1.99.3 5.599e-263 821.0
HFD2_k127_4586962_30 Spermidine putrescine-binding periplasmic protein K02055 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 325.0
HFD2_k127_4586962_31 PFAM Polyphosphate kinase 2 K22468 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 312.0
HFD2_k127_4586962_32 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 304.0
HFD2_k127_4586962_33 alpha/beta hydrolase fold K01066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 307.0
HFD2_k127_4586962_34 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009073 291.0
HFD2_k127_4586962_35 Conserved hypothetical protein (DUF2461) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005999 278.0
HFD2_k127_4586962_36 Gluconate 2-dehydrogenase subunit 3 K06152 - 1.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000897 276.0
HFD2_k127_4586962_37 4,5-dihydroxyphthalate decarboxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000002861 235.0
HFD2_k127_4586962_38 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000001382 231.0
HFD2_k127_4586962_39 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000004165 208.0
HFD2_k127_4586962_4 Belongs to the ABC transporter superfamily K02031,K02032 - - 4.378e-255 801.0
HFD2_k127_4586962_40 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000000000000137 199.0
HFD2_k127_4586962_41 Carboxylesterase family - - - 0.0000000000000000000000000000000000000000000000000000001697 212.0
HFD2_k127_4586962_42 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls - - - 0.000000000000000000000000000000000000000000000000000001272 208.0
HFD2_k127_4586962_43 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000002366 188.0
HFD2_k127_4586962_44 transporter component K07112 - - 0.000000000000000000000000000000000000000000000003736 180.0
HFD2_k127_4586962_45 Bacterial protein of unknown function (DUF924) - - - 0.000000000000000000000000000000000000000000000007296 181.0
HFD2_k127_4586962_46 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000672 173.0
HFD2_k127_4586962_47 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.000000000000000000000000000000000000000000004851 165.0
HFD2_k127_4586962_48 transporter component K07112 - - 0.0000000000000000000000000000000000000000009233 160.0
HFD2_k127_4586962_49 chain release factor K15034 - - 0.000000000000000000000000000000000000000002276 159.0
HFD2_k127_4586962_5 - - - - 5.244e-203 657.0
HFD2_k127_4586962_50 MOSC domain - - - 0.00000000000000000000000000000000000005251 147.0
HFD2_k127_4586962_51 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000001678 131.0
HFD2_k127_4586962_52 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000000001638 126.0
HFD2_k127_4586962_53 Cytochrome c2 K08738 - - 0.00000000000000000000000000001503 124.0
HFD2_k127_4586962_54 Belongs to the ompA family - - - 0.00000000000000000000000008904 115.0
HFD2_k127_4586962_55 SPTR Transcriptional regulator, AraC family K07506 - - 0.00000000000000000000006918 102.0
HFD2_k127_4586962_56 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000000000000001753 99.0
HFD2_k127_4586962_57 Protein required for attachment to host cells - - - 0.00000000000000000001097 97.0
HFD2_k127_4586962_58 - - - - 0.0000000000000000002976 94.0
HFD2_k127_4586962_59 PFAM Cysteine-rich secretory protein family - - - 0.000000000000002652 83.0
HFD2_k127_4586962_6 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822,K00833 - 2.6.1.18,2.6.1.62 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 546.0
HFD2_k127_4586962_61 - - - - 0.0000000000002058 75.0
HFD2_k127_4586962_62 protein conserved in bacteria - - - 0.00000000003844 70.0
HFD2_k127_4586962_63 - - - - 0.000000001457 65.0
HFD2_k127_4586962_64 Sh3 type 3 domain protein K01447,K09774 - 3.5.1.28 0.0000007067 62.0
HFD2_k127_4586962_7 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008141 538.0
HFD2_k127_4586962_8 COG1178 ABC-type Fe3 transport system, permease component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 535.0
HFD2_k127_4586962_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 527.0
HFD2_k127_4589108_0 peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 516.0
HFD2_k127_4589108_1 tRNA 3'-trailer cleavage - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004921 355.0
HFD2_k127_4589108_2 transcription regulator containing HTH domain K18831 - - 0.0000000000000000000000000000000000000000001992 162.0
HFD2_k127_4589108_3 protein conserved in bacteria K19166 - - 0.00000000000000000000000000000000000000006092 152.0
HFD2_k127_4589108_4 COG0477 Permeases of the major facilitator superfamily K07552 - - 0.0000000000003409 76.0
HFD2_k127_4589108_6 TIGRFAM Addiction module antidote protein, HigA K21498 - - 0.00001975 47.0
HFD2_k127_4589108_7 Helix-turn-helix XRE-family like proteins K21498 - - 0.0002263 45.0
HFD2_k127_4652957_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000782 413.0
HFD2_k127_4652957_1 - - - - 0.000000000000000000000000000000000000000000000000000000126 198.0
HFD2_k127_4652957_2 ABC transporter substrate binding protein K01989 - - 0.000003068 51.0
HFD2_k127_4664128_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 2.939e-211 669.0
HFD2_k127_4664128_1 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004954 316.0
HFD2_k127_4664128_2 thiamine-containing compound biosynthetic process K02051,K15553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002351 278.0
HFD2_k127_4664128_3 Uncharacterized BCR, YaiI/YqxD family COG1671 K09768 - - 0.0000000000000000000000000000000000000000000000000000005517 197.0
HFD2_k127_4664128_4 2OG-Fe(II) oxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000001872 181.0
HFD2_k127_4664128_5 Acid phosphatase homologues K09474 - 3.1.3.2 0.00000000000000000000000000000000000000007332 162.0
HFD2_k127_4664128_6 Cytochrome C oxidase, cbb3-type, subunit III K19713 - 1.8.2.2 0.000000003374 63.0
HFD2_k127_4714345_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.272e-290 915.0
HFD2_k127_4714345_1 NusA-like KH domain K02600 - - 2.281e-246 769.0
HFD2_k127_4714345_10 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 353.0
HFD2_k127_4714345_11 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 341.0
HFD2_k127_4714345_12 Imidazoleglycerol-phosphate dehydratase K00817,K01089,K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.9,3.1.3.15,4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 313.0
HFD2_k127_4714345_13 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003177 313.0
HFD2_k127_4714345_14 ABC-2 type transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003955 307.0
HFD2_k127_4714345_15 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004552 274.0
HFD2_k127_4714345_16 COG4567 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain K15012 GO:0000156,GO:0000160,GO:0003674,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0023052,GO:0035556,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005024 270.0
HFD2_k127_4714345_17 - - - - 0.00000000000000000000000000000000000000000000000000000000000000009347 228.0
HFD2_k127_4714345_18 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.000000000000000000000000000000000000000000000000000000000000001119 231.0
HFD2_k127_4714345_19 - - - - 0.00000000000000000000000000000000000000000000000000000000000006715 223.0
HFD2_k127_4714345_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 8.059e-206 645.0
HFD2_k127_4714345_20 - - - - 0.00000000000000000000000000000000000000000000000000000108 200.0
HFD2_k127_4714345_21 CHASE2 K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000003658 201.0
HFD2_k127_4714345_22 protein SCO1 SenC K07152 - - 0.000000000000000000000000000000000000000000000009436 178.0
HFD2_k127_4714345_24 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000001625 173.0
HFD2_k127_4714345_25 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000000000000000005326 164.0
HFD2_k127_4714345_26 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000037 172.0
HFD2_k127_4714345_27 Protein of unknown function (DUF448) K07742 - - 0.00000000000000000000000000000000000000005039 162.0
HFD2_k127_4714345_28 DNA repair protein MmcB-like - - - 0.0000000000000000000000000000000000007189 151.0
HFD2_k127_4714345_29 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000009673 137.0
HFD2_k127_4714345_3 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 5.634e-205 651.0
HFD2_k127_4714345_30 YGGT family K02221 - - 0.00000000000000000000000004317 111.0
HFD2_k127_4714345_31 - - - - 0.000000000000000000005699 104.0
HFD2_k127_4714345_32 Belongs to the UPF0235 family K09131 - - 0.00000000000000001048 93.0
HFD2_k127_4714345_33 - - - - 0.0000000000000003375 84.0
HFD2_k127_4714345_36 protease with the C-terminal PDZ - - - 0.00000002436 61.0
HFD2_k127_4714345_37 Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate - - - 0.00000003507 56.0
HFD2_k127_4714345_38 Domain of unknown function (DUF4142) - - - 0.00000067 61.0
HFD2_k127_4714345_4 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 569.0
HFD2_k127_4714345_5 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003649 542.0
HFD2_k127_4714345_6 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 414.0
HFD2_k127_4714345_7 Histidine kinase K15011 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003148 413.0
HFD2_k127_4714345_8 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006456 363.0
HFD2_k127_4714345_9 mandelate racemase muconate lactonizing K19802 - 5.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 365.0
HFD2_k127_4774238_0 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 5.272e-225 729.0
HFD2_k127_4774238_1 Glycosyl transferase family 41 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 558.0
HFD2_k127_4774238_2 Alginate export - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 511.0
HFD2_k127_4774238_3 Glycosyl transferase family 41 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005742 361.0
HFD2_k127_4774238_4 ABC transporter, periplasmic molybdate-binding protein K02020 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015098,GO:0015103,GO:0015318,GO:0015399,GO:0015405,GO:0015412,GO:0015689,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0030151,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0034220,GO:0042597,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043169,GO:0043225,GO:0043492,GO:0044464,GO:0046872,GO:0046914,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0099133,GO:1901359 - 0.0000000000000000000000000000000000000000000000000000000000000000000007197 245.0
HFD2_k127_4774238_5 - - - - 0.0000000000000000001231 95.0
HFD2_k127_477639_0 - - - - 2.176e-273 859.0
HFD2_k127_477639_1 Uncharacterised MFS-type transporter YbfB K08369 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 516.0
HFD2_k127_477639_10 STAS domain - - - 0.0000000000000000000000004881 108.0
HFD2_k127_477639_11 - - - - 0.0000000000000000000001342 110.0
HFD2_k127_477639_12 Cytochrome c - - - 0.00000000000000000758 87.0
HFD2_k127_477639_13 anti-sigma regulatory factor, serine threonine protein kinase K04757 - 2.7.11.1 0.00000000000000001537 88.0
HFD2_k127_477639_14 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000003149 94.0
HFD2_k127_477639_15 - - - - 0.00000000127 63.0
HFD2_k127_477639_2 Mo-co oxidoreductase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 508.0
HFD2_k127_477639_3 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 318.0
HFD2_k127_477639_4 FHA Domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 308.0
HFD2_k127_477639_5 COG0515 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000001107 160.0
HFD2_k127_477639_6 Methyltransferase FkbM domain - - - 0.00000000000000000000000000000000000000002952 166.0
HFD2_k127_477639_7 - - - - 0.00000000000000000000000001551 121.0
HFD2_k127_477639_8 - - - - 0.00000000000000000000000004668 118.0
HFD2_k127_477639_9 - - - - 0.00000000000000000000000005459 118.0
HFD2_k127_478079_0 Biotin carboxylase C-terminal domain K01965 GO:0003674,GO:0003824,GO:0004658,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009374,GO:0009987,GO:0016421,GO:0016874,GO:0016885,GO:0017144,GO:0019752,GO:0019842,GO:0019899,GO:0031406,GO:0031974,GO:0032787,GO:0033218,GO:0033293,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0070013,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901681 6.4.1.3 0.0 1017.0
HFD2_k127_478079_1 C-terminal domain of 1-Cys peroxiredoxin K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 406.0
HFD2_k127_478079_2 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009646 354.0
HFD2_k127_478079_3 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000765 340.0
HFD2_k127_478079_4 Domain of unknown function (DUF4442) - - - 0.00000000000000000000000000000000000000000004296 163.0
HFD2_k127_478079_5 PFAM AIG2 family protein - - - 0.00000000000000000000000000000002242 131.0
HFD2_k127_478079_6 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.00000000000000000000000000001943 124.0
HFD2_k127_478079_7 Type III flagellar switch regulator (C-ring) FliN C-term K02417 - - 0.000000000000000000009283 93.0
HFD2_k127_4823865_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 3.354e-309 964.0
HFD2_k127_4823865_1 ABC transporter K06158 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 7.097e-205 655.0
HFD2_k127_4823865_10 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 450.0
HFD2_k127_4823865_11 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 424.0
HFD2_k127_4823865_12 Protein of unknown function (DUF815) K06923 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 393.0
HFD2_k127_4823865_13 malonyl CoA-acyl carrier protein transacylase K00645,K15327 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 362.0
HFD2_k127_4823865_14 Enoyl-(Acyl carrier protein) reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008903 345.0
HFD2_k127_4823865_15 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005916 347.0
HFD2_k127_4823865_16 Predicted permease YjgP/YjgQ family K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 343.0
HFD2_k127_4823865_17 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 335.0
HFD2_k127_4823865_18 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003175 330.0
HFD2_k127_4823865_19 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 323.0
HFD2_k127_4823865_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.179 3.306e-202 636.0
HFD2_k127_4823865_20 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 323.0
HFD2_k127_4823865_21 Leucine carboxyl methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 316.0
HFD2_k127_4823865_22 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003864 308.0
HFD2_k127_4823865_23 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000009489 265.0
HFD2_k127_4823865_24 Domain of unknown function (DUF1732) - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000002881 260.0
HFD2_k127_4823865_25 Predicted permease YjgP/YjgQ family K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003624 261.0
HFD2_k127_4823865_26 Urate oxidase N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006315 250.0
HFD2_k127_4823865_27 Chaperone SurA K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000865 266.0
HFD2_k127_4823865_28 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004866 252.0
HFD2_k127_4823865_29 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000001197 254.0
HFD2_k127_4823865_3 AsmA family K07290 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 602.0
HFD2_k127_4823865_30 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000002324 224.0
HFD2_k127_4823865_31 DNA polymerase III chi subunit, HolC K02339 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000001732 196.0
HFD2_k127_4823865_32 Lysin motif K06194 - - 0.000000000000000000000000000000000000000000000006301 185.0
HFD2_k127_4823865_33 Uncharacterized protein conserved in bacteria (DUF2066) - - - 0.000000000000000000000000000000000000000001273 171.0
HFD2_k127_4823865_34 Domain of unknown function (DUF4440) - - - 0.000000000000000000000000000000000000000003578 158.0
HFD2_k127_4823865_35 - - - - 0.0000000000000000000000000000000000000892 149.0
HFD2_k127_4823865_36 COG0593 ATPase involved in DNA replication initiation - - - 0.0000000000000000000000000000000000004084 160.0
HFD2_k127_4823865_37 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000000000000000008932 132.0
HFD2_k127_4823865_38 protein conserved in bacteria K09984 - - 0.000000000000000000000000000000003427 130.0
HFD2_k127_4823865_39 Preprotein translocase subunit K03210 - - 0.00000000000000000000000000003833 118.0
HFD2_k127_4823865_4 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 579.0
HFD2_k127_4823865_40 Phytoene squalene synthetase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000001096 118.0
HFD2_k127_4823865_41 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.000000000000000000000000009668 116.0
HFD2_k127_4823865_43 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 GO:0003674,GO:0005215 - 0.000000000000000000005855 98.0
HFD2_k127_4823865_44 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 GO:0003674,GO:0005215 - 0.00000000000000003821 83.0
HFD2_k127_4823865_45 Evidence 4 Homologs of previously reported genes of - - - 0.000007061 56.0
HFD2_k127_4823865_5 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005672 558.0
HFD2_k127_4823865_6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007039 541.0
HFD2_k127_4823865_7 Major Facilitator Superfamily K13021 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 499.0
HFD2_k127_4823865_8 4,5-dihydroxyphthalate decarboxylase K04102 - 4.1.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 482.0
HFD2_k127_4823865_9 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 479.0
HFD2_k127_4890691_0 PFAM Glycosyl transferase family 2 - - - 8.666e-264 841.0
HFD2_k127_4890691_1 Domain of unknown function DUF21 K03699 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007249 559.0
HFD2_k127_4890691_10 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002371 255.0
HFD2_k127_4890691_11 Uncharacterised protein family (UPF0262) - - - 0.0000000000000000000000000000000000000000000000000000001727 198.0
HFD2_k127_4890691_12 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000004497 199.0
HFD2_k127_4890691_13 Serine/threonine phosphatases, family 2C, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000003407 201.0
HFD2_k127_4890691_14 OsmC-like protein K04063 - - 0.0000000000000000000000000000000000000000000000000001958 188.0
HFD2_k127_4890691_15 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000000000000179 142.0
HFD2_k127_4890691_16 LysM domain - - - 0.00000000000000000000000000000003119 140.0
HFD2_k127_4890691_17 - - - - 0.000000000000000000000000001354 123.0
HFD2_k127_4890691_18 Histidine kinase - - - 0.00000000000000000005697 91.0
HFD2_k127_4890691_19 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000000004433 77.0
HFD2_k127_4890691_2 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 542.0
HFD2_k127_4890691_20 - - - - 0.0001063 47.0
HFD2_k127_4890691_3 ABC-type multidrug transport system ATPase and permease K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 483.0
HFD2_k127_4890691_4 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 464.0
HFD2_k127_4890691_5 Dehydratase K08678 - 4.1.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004144 461.0
HFD2_k127_4890691_6 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000541 451.0
HFD2_k127_4890691_7 COG0515 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 412.0
HFD2_k127_4890691_8 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784,K12448 - 5.1.3.2,5.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005884 409.0
HFD2_k127_4890691_9 ABC-type multidrug transport system ATPase and permease K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003486 400.0
HFD2_k127_4900662_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 1.294e-295 921.0
HFD2_k127_4900662_1 Sigma-54 interaction domain K10943 - - 2.583e-206 649.0
HFD2_k127_4900662_10 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02417 GO:0005575,GO:0005623,GO:0005886,GO:0009288,GO:0009425,GO:0016020,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000001645 141.0
HFD2_k127_4900662_11 Flagellar biosynthesis type III secretory pathway protein K02411 - - 0.00000000000000006344 92.0
HFD2_k127_4900662_13 - - - - 0.00000000008467 65.0
HFD2_k127_4900662_14 - - - - 0.0003638 46.0
HFD2_k127_4900662_2 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004515 513.0
HFD2_k127_4900662_3 The M ring may be actively involved in energy transduction K02409 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 460.0
HFD2_k127_4900662_4 Flagellar hook protein FlgE K02390 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 348.0
HFD2_k127_4900662_5 Acyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001795 282.0
HFD2_k127_4900662_6 COG2826 Transposase and inactivated derivatives, IS30 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002476 272.0
HFD2_k127_4900662_7 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.000000000000000000000000000000000000000000004535 171.0
HFD2_k127_4900662_8 Protein of unknown function (DUF1153) - - - 0.00000000000000000000000000000000000000000002351 162.0
HFD2_k127_4900662_9 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.000000000000000000000000000000000000001758 155.0
HFD2_k127_4987818_0 PFAM Rieske 2Fe-2S domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 335.0
HFD2_k127_4987818_1 helix_turn_helix isocitrate lyase regulation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006137 321.0
HFD2_k127_4987818_2 Cytochrome C' - - - 0.0000000000000000000000000000000002147 143.0
HFD2_k127_4987818_3 CopG antitoxin of type II toxin-antitoxin system - - - 0.00000000000000000000009256 100.0
HFD2_k127_4987818_4 - - - - 0.00000000000000006773 87.0
HFD2_k127_5050893_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 437.0
HFD2_k127_5050893_1 Methylates ribosomal protein L11 K02687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006053 258.0
HFD2_k127_5050893_2 iron dependent repressor K03709 - - 0.000000000000000000000005684 105.0
HFD2_k127_5056618_0 HNH endonuclease K07454 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003816 394.0
HFD2_k127_5056618_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 379.0
HFD2_k127_5056618_2 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000003252 199.0
HFD2_k127_5076814_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004096 429.0
HFD2_k127_5076814_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 327.0
HFD2_k127_5076814_2 PFAM type II secretion system protein E K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 320.0
HFD2_k127_5076814_3 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000001855 71.0
HFD2_k127_5092219_0 Thi4 family - - - 2.615e-205 649.0
HFD2_k127_5092219_1 Oxidoreductase - - - 4.648e-200 625.0
HFD2_k127_5092219_2 - - - - 0.0000000000000000000000000003258 125.0
HFD2_k127_5092219_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0005125 49.0
HFD2_k127_519356_0 COG0841 Cation multidrug efflux pump K18902,K19594 - - 0.0 1631.0
HFD2_k127_519356_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K18901,K19595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 450.0
HFD2_k127_519356_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 379.0
HFD2_k127_519356_3 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001054 281.0
HFD2_k127_519356_4 PFAM Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004434 287.0
HFD2_k127_519356_5 Cro/C1-type HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001663 258.0
HFD2_k127_519356_6 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000001143 192.0
HFD2_k127_519356_7 metal-dependent hydrolase with the TIM-barrel fold - - - 0.00000000000000000000000000000000000000005452 161.0
HFD2_k127_519356_8 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000009642 138.0
HFD2_k127_519356_9 Protein of unknown function (DUF1697) - - - 0.000000003026 68.0
HFD2_k127_5202191_0 Hydantoinase/oxoprolinase N-terminal region K01469 - 3.5.2.9 0.0 1016.0
HFD2_k127_5202191_1 succinate dehydrogenase - - - 8.386e-196 627.0
HFD2_k127_5202191_2 Domain of unknown function (DUF4349) - - - 0.00000000000000000000000000000000000000000000002867 183.0
HFD2_k127_5202191_3 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000001281 173.0
HFD2_k127_5202191_5 - - - - 0.00000000000000000000001789 115.0
HFD2_k127_5202191_6 - - - - 0.0000000000000000003955 98.0
HFD2_k127_5202191_7 Nickel/cobalt transporter regulator - - - 0.000000001913 66.0
HFD2_k127_5202191_8 Phospholipase - - - 0.000003288 57.0
HFD2_k127_5214089_0 Transposase and inactivated derivatives - - - 0.0 1024.0
HFD2_k127_5214089_1 Transposase K07487 - - 3.423e-215 677.0
HFD2_k127_5214089_2 IstB-like ATP binding N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 498.0
HFD2_k127_5214089_3 ABC transporter substrate binding protein - - - 0.00000000000000000001176 92.0
HFD2_k127_5214089_4 Uncharacterized conserved protein (DUF2075) - - - 0.00000000001082 68.0
HFD2_k127_5276837_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015627,GO:0015628,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:0098776,GO:1901265,GO:1901363,GO:1904680 - 0.0 1244.0
HFD2_k127_5276837_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1195.0
HFD2_k127_5276837_10 Belongs to the 'phage' integrase family. XerC subfamily K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 317.0
HFD2_k127_5276837_11 Belongs to the peptidase S1B family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002028 280.0
HFD2_k127_5276837_12 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000225 263.0
HFD2_k127_5276837_13 Belongs to the Nudix hydrolase family K03574 GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000001477 216.0
HFD2_k127_5276837_14 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.00000000000000000000000000000000000000000000000000000000001949 212.0
HFD2_k127_5276837_15 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000001949 198.0
HFD2_k127_5276837_16 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.0000000000000000000000000000000000000000000001491 168.0
HFD2_k127_5276837_17 Ndr family K14727 - 3.1.1.24,4.1.1.44 0.000000000000000000000000000000000000000000000191 173.0
HFD2_k127_5276837_18 Helix-turn-helix XRE-family like proteins K21498 - - 0.000000000000000000000000000000000000000000005846 165.0
HFD2_k127_5276837_19 - - - - 0.00000000000000000000002724 116.0
HFD2_k127_5276837_2 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 3.499e-289 896.0
HFD2_k127_5276837_20 Stress-induced bacterial acidophilic repeat motif K06884 - - 0.000000000000000000001187 99.0
HFD2_k127_5276837_3 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 496.0
HFD2_k127_5276837_4 PrpF protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 442.0
HFD2_k127_5276837_5 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 435.0
HFD2_k127_5276837_6 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 426.0
HFD2_k127_5276837_7 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 366.0
HFD2_k127_5276837_8 Transporter associated domain K03699 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 355.0
HFD2_k127_5276837_9 protein involved in formation of curli polymers - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006745 335.0
HFD2_k127_5277559_0 Enoyl-CoA hydratase K13816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002118 268.0
HFD2_k127_5277559_1 Diguanylate cyclase - - - 0.00000000000000000000001525 102.0
HFD2_k127_5277559_2 histidine kinase A domain protein K07647,K07678 - 2.7.13.3 0.0000000000000000002702 96.0
HFD2_k127_5296847_0 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 2.405e-292 913.0
HFD2_k127_5296847_1 recombinase activity K06400 - - 0.000000000000000000000000000000000000000000000000000004299 204.0
HFD2_k127_5296847_2 Hydantoinase B/oxoprolinase - - - 0.00000000773 60.0
HFD2_k127_5297169_0 TIGRFAM Phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005755 292.0
HFD2_k127_5297169_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000002933 192.0
HFD2_k127_5346212_0 amino acid peptide transporter K03305 - - 4.832e-242 762.0
HFD2_k127_5346212_1 Pyridoxal-phosphate dependent enzyme K01738 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 530.0
HFD2_k127_5346212_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002524 278.0
HFD2_k127_5346212_11 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000005418 214.0
HFD2_k127_5346212_12 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000009658 218.0
HFD2_k127_5346212_13 lactoylglutathione lyase activity K03088 - - 0.00000000000000000000000000000000000000000000000000000000001452 216.0
HFD2_k127_5346212_14 - - - - 0.000000000000000000000000000000000000000000000000004558 188.0
HFD2_k127_5346212_15 Belongs to the ClpA ClpB family K03694 - - 0.000000000000000000000000000000000000000004775 163.0
HFD2_k127_5346212_16 Phosphoribosyl-AMP cyclohydrolase K01496 - 3.5.4.19 0.000000000000000000000000000000000000000008703 156.0
HFD2_k127_5346212_17 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000004658 157.0
HFD2_k127_5346212_18 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000001737 147.0
HFD2_k127_5346212_19 Isochorismatase family - - - 0.00000000000000000000000000000000004158 143.0
HFD2_k127_5346212_2 SMP-30/Gluconolaconase/LRE-like region K01053,K14274 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003331 482.0
HFD2_k127_5346212_20 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000004396 140.0
HFD2_k127_5346212_21 - - - - 0.0000000000000000000000000000000001585 137.0
HFD2_k127_5346212_22 - - - - 0.000000000000000000000000000000000269 145.0
HFD2_k127_5346212_23 Plasmid maintenance system killer K07334 - - 0.00000000000000000000000000001365 120.0
HFD2_k127_5346212_24 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000001171 113.0
HFD2_k127_5346212_25 Protein of unknown function (DUF3175) - - - 0.0000000000000000000000002684 120.0
HFD2_k127_5346212_26 Helix-turn-helix domain K21498 - - 0.0000000000000000000000003405 108.0
HFD2_k127_5346212_27 Domain of unknown function (DUF4160) - - - 0.000000000000000000000003496 103.0
HFD2_k127_5346212_28 Bacterial extracellular solute-binding protein - - - 0.000000000000000000000157 110.0
HFD2_k127_5346212_29 - - - - 0.0000000000000000000005404 107.0
HFD2_k127_5346212_3 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 448.0
HFD2_k127_5346212_30 Protein of unknown function (DUF2442) - - - 0.000000000000000000001657 100.0
HFD2_k127_5346212_32 Transposase IS116/IS110/IS902 family K07486 - - 0.00000007531 53.0
HFD2_k127_5346212_4 PFAM Cys Met metabolism PLP-dependent enzyme K01760 GO:0000096,GO:0000098,GO:0000724,GO:0000725,GO:0003674,GO:0003824,GO:0004121,GO:0006082,GO:0006090,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006520,GO:0006534,GO:0006725,GO:0006790,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009093,GO:0009987,GO:0016054,GO:0016829,GO:0016846,GO:0019448,GO:0019450,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044273,GO:0044281,GO:0044282,GO:0046395,GO:0046439,GO:0046483,GO:0047804,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1990414 4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004159 447.0
HFD2_k127_5346212_5 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009851 405.0
HFD2_k127_5346212_6 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005661 407.0
HFD2_k127_5346212_7 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 350.0
HFD2_k127_5346212_8 Sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006673 312.0
HFD2_k127_5346212_9 Cupin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000271 280.0
HFD2_k127_54211_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 588.0
HFD2_k127_54211_1 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282,K18008 - 1.12.2.1,1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 496.0
HFD2_k127_54211_2 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 0.00000000000000000000000000521 111.0
HFD2_k127_5422565_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 1.18e-255 811.0
HFD2_k127_5422565_1 Belongs to the UbiD family K03182 - 4.1.1.98 3.16e-230 726.0
HFD2_k127_5422565_10 Permease family - - - 0.0000000000000000000000000000009855 125.0
HFD2_k127_5422565_11 Antidote-toxin recognition MazE, bacterial antitoxin K18829 - - 0.00000000000000000000009151 99.0
HFD2_k127_5422565_2 Sugar (and other) transporter K08195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 613.0
HFD2_k127_5422565_3 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007741 310.0
HFD2_k127_5422565_4 PFAM class II aldolase adducin family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000006209 244.0
HFD2_k127_5422565_5 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.000000000000000000000000000000000000000000000000000000000001861 220.0
HFD2_k127_5422565_6 Putative molybdenum carrier - - - 0.0000000000000000000000000000000000000000000001514 177.0
HFD2_k127_5422565_7 Transcriptional regulator - - - 0.0000000000000000000000000000000000000003206 151.0
HFD2_k127_5422565_9 - - - - 0.000000000000000000000000000000000004529 138.0
HFD2_k127_5455169_0 PFAM short-chain dehydrogenase reductase SDR - - - 0.0 2335.0
HFD2_k127_5455169_1 PEP-utilising enzyme, TIM barrel domain K01007 - 2.7.9.2 0.0 1266.0
HFD2_k127_5455169_10 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 426.0
HFD2_k127_5455169_11 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004411 424.0
HFD2_k127_5455169_12 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 413.0
HFD2_k127_5455169_13 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 372.0
HFD2_k127_5455169_14 Aminoglycoside phosphotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006011 335.0
HFD2_k127_5455169_15 Isochorismatase family K08281 - 3.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000731 302.0
HFD2_k127_5455169_16 AraC type K13529 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 298.0
HFD2_k127_5455169_17 Gluconate 2-dehydrogenase subunit 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 294.0
HFD2_k127_5455169_18 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 297.0
HFD2_k127_5455169_19 Phosphoribosyl transferase domain K07100 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001331 283.0
HFD2_k127_5455169_2 Tripartite tricarboxylate transporter TctA family - - - 1.269e-255 805.0
HFD2_k127_5455169_20 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003,K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004762 243.0
HFD2_k127_5455169_21 - - - - 0.00000000000000000000000000000000000000000000000000000000000000007247 228.0
HFD2_k127_5455169_22 short-chain dehydrogenase reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000001495 229.0
HFD2_k127_5455169_23 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000001629 211.0
HFD2_k127_5455169_24 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000000000000000005012 191.0
HFD2_k127_5455169_25 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000000000000000000000000000000000000000000000000001861 196.0
HFD2_k127_5455169_26 Archease protein family (MTH1598/TM1083) - - - 0.0000000000000000000000000000000000000000000166 166.0
HFD2_k127_5455169_27 Uncharacterized conserved protein (DUF2267) - - - 0.000000000000000000000000000000000000000003391 160.0
HFD2_k127_5455169_28 PFAM glycosyl transferase family 9 - - - 0.00000000000000000000000000003677 126.0
HFD2_k127_5455169_29 Protein of unknown function (DUF3775) - - - 0.0000000000000000000000000004497 119.0
HFD2_k127_5455169_3 GMC oxidoreductase - - - 4.155e-231 729.0
HFD2_k127_5455169_30 Protein of unknown function (DUF1778) - - - 0.00000000000000000000000002106 121.0
HFD2_k127_5455169_31 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K03778 - 1.1.1.28 0.00000000000000000000001664 103.0
HFD2_k127_5455169_32 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.00000000000000000004112 91.0
HFD2_k127_5455169_33 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K03778 - 1.1.1.28 0.000000000000001741 78.0
HFD2_k127_5455169_34 - - - - 0.00000000000002566 80.0
HFD2_k127_5455169_35 Protein of unknown function (DUF2934) - - - 0.000002543 53.0
HFD2_k127_5455169_36 intermembrane phospholipid transfer K07323 - - 0.000005153 56.0
HFD2_k127_5455169_4 PQQ enzyme repeat K00114 - 1.1.2.8 2.175e-219 696.0
HFD2_k127_5455169_5 RTCB protein K14415 - 6.5.1.3 4.224e-216 679.0
HFD2_k127_5455169_6 Nicotinate phosphoribosyltransferase (NAPRTase) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000449 617.0
HFD2_k127_5455169_7 Cys/Met metabolism PLP-dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008195 527.0
HFD2_k127_5455169_8 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003758 484.0
HFD2_k127_5455169_9 Tetratricopeptide repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004887 457.0
HFD2_k127_5468133_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 7.003e-290 903.0
HFD2_k127_5468133_1 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 1.269e-285 891.0
HFD2_k127_5468133_10 TIGRFAM 4-hydroxybenzoate 3-monooxygenase K00481 GO:0000166,GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016705,GO:0016709,GO:0018659,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363 1.14.13.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006293 529.0
HFD2_k127_5468133_11 fructose-bisphosphate aldolase K01623 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007821 515.0
HFD2_k127_5468133_12 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009882 507.0
HFD2_k127_5468133_13 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 507.0
HFD2_k127_5468133_14 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 508.0
HFD2_k127_5468133_15 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 487.0
HFD2_k127_5468133_16 transcriptional regulator, araC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 481.0
HFD2_k127_5468133_17 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 478.0
HFD2_k127_5468133_18 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 476.0
HFD2_k127_5468133_19 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 443.0
HFD2_k127_5468133_2 P-type ATPase K17686 - 3.6.3.54 1.403e-252 795.0
HFD2_k127_5468133_20 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000996 414.0
HFD2_k127_5468133_21 proteins, homologs of microcin C7 resistance protein MccF - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 376.0
HFD2_k127_5468133_22 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 371.0
HFD2_k127_5468133_23 YmdB-like protein K09769 GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0016787,GO:0016788,GO:0042578 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 370.0
HFD2_k127_5468133_24 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 362.0
HFD2_k127_5468133_25 TIGRFAM PQQ-dependent dehydrogenase, methanol ethanol family K00114 - 1.1.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 350.0
HFD2_k127_5468133_26 Sugar (and other) transporter K08195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003839 342.0
HFD2_k127_5468133_27 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 329.0
HFD2_k127_5468133_28 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005392 332.0
HFD2_k127_5468133_29 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008972 319.0
HFD2_k127_5468133_3 Zinc metalloprotease (Elastase) K01400,K01417,K20274 - 3.4.24.28 9.931e-237 764.0
HFD2_k127_5468133_30 Peptidase family S58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007923 321.0
HFD2_k127_5468133_31 Protein of unknown function (DUF1282) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 324.0
HFD2_k127_5468133_32 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004751 321.0
HFD2_k127_5468133_33 Major facilitator superfamily K08191 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 322.0
HFD2_k127_5468133_34 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003927 306.0
HFD2_k127_5468133_35 VirC1 protein K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 298.0
HFD2_k127_5468133_36 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 293.0
HFD2_k127_5468133_37 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005283 284.0
HFD2_k127_5468133_38 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001267 276.0
HFD2_k127_5468133_39 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002954 278.0
HFD2_k127_5468133_4 ABC transporter transmembrane region K06147 - - 4.441e-220 698.0
HFD2_k127_5468133_40 Universal stress protein family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002017 275.0
HFD2_k127_5468133_41 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005356 274.0
HFD2_k127_5468133_42 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001467 266.0
HFD2_k127_5468133_43 MotA/TolQ/ExbB proton channel family K03562 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0017038,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002285 268.0
HFD2_k127_5468133_44 Histidine kinase K07716 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000006176 260.0
HFD2_k127_5468133_45 lactoylglutathione lyase activity K03088 - - 0.00000000000000000000000000000000000000000000000000000000000001096 226.0
HFD2_k127_5468133_46 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K02006,K16786,K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000352 234.0
HFD2_k127_5468133_47 cation diffusion facilitator family transporter - - - 0.00000000000000000000000000000000000000000000000000000000003791 211.0
HFD2_k127_5468133_48 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000001205 219.0
HFD2_k127_5468133_49 WYL domain - - - 0.000000000000000000000000000000000000000000000000000003239 199.0
HFD2_k127_5468133_5 MmgE/PrpD family - - - 2.693e-210 666.0
HFD2_k127_5468133_50 Acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000004647 205.0
HFD2_k127_5468133_51 Domain of unknown function (DUF1772) - - - 0.00000000000000000000000000000000000000000000000000002787 192.0
HFD2_k127_5468133_52 Protein of unknown function (DUF1194) - - - 0.00000000000000000000000000000000000000000000000000003488 199.0
HFD2_k127_5468133_53 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 0.0000000000000000000000000000000000000000000000000004059 198.0
HFD2_k127_5468133_54 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000000005836 189.0
HFD2_k127_5468133_55 PFAM Glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.0000000000000000000000000000000000000000000000000008283 186.0
HFD2_k127_5468133_56 MarR family - - - 0.000000000000000000000000000000000000000000000000009445 184.0
HFD2_k127_5468133_57 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.0000000000000000000000000000000000000000000000002519 182.0
HFD2_k127_5468133_58 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000000000003595 182.0
HFD2_k127_5468133_59 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000000000000000000000000000000000000000000003762 181.0
HFD2_k127_5468133_6 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases K01426 - 3.5.1.4 5.646e-198 630.0
HFD2_k127_5468133_60 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000001806 166.0
HFD2_k127_5468133_61 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000002715 160.0
HFD2_k127_5468133_62 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 - - 0.00000000000000000000000000000000000000002383 164.0
HFD2_k127_5468133_63 extracellular solute-binding protein, family 1 K02020,K22003 - 5.3.3.7 0.0000000000000000000000000000000000000001083 160.0
HFD2_k127_5468133_64 Universal stress protein - - - 0.000000000000000000000000000000000000001466 158.0
HFD2_k127_5468133_65 Tol-pal system-associated acyl-CoA thioesterase K07107 - - 0.0000000000000000000000000000000000001451 147.0
HFD2_k127_5468133_66 Cell division and transport-associated protein TolA K03646 - - 0.00000000000000000000000000000000002091 145.0
HFD2_k127_5468133_67 FR47-like protein - - - 0.00000000000000000000000000000000004583 140.0
HFD2_k127_5468133_68 Activator of Hsp90 ATPase - - - 0.000000000000000000000000000000007893 145.0
HFD2_k127_5468133_69 Bacterial periplasmic substrate-binding proteins K02030 - - 0.00000000000000000000000000000006095 138.0
HFD2_k127_5468133_7 Mur ligase family, catalytic domain - - - 7.797e-197 623.0
HFD2_k127_5468133_70 - - - - 0.00000000000000000000000000002619 128.0
HFD2_k127_5468133_71 - - - - 0.00000000000000000000000000003039 121.0
HFD2_k127_5468133_72 nuclease activity K00640,K07062 - 2.3.1.30 0.0000000000000000000000000009211 121.0
HFD2_k127_5468133_73 - - - - 0.00000000000000000000000001298 120.0
HFD2_k127_5468133_74 Protein of unknown function (DUF3574) - - - 0.0000000000000000000000001101 111.0
HFD2_k127_5468133_75 - - - - 0.0000000000000000000000002463 115.0
HFD2_k127_5468133_76 Nucleotidyltransferase domain K07075 - - 0.000000000000000000000001268 106.0
HFD2_k127_5468133_77 PFAM Uncharacterised protein family (UPF0153) - - - 0.000000000000000000000003435 109.0
HFD2_k127_5468133_78 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000002272 111.0
HFD2_k127_5468133_79 - - - - 0.00000000000000000000003836 110.0
HFD2_k127_5468133_8 Involved in the TonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004055 583.0
HFD2_k127_5468133_80 Polymer-forming cytoskeletal - - - 0.0000000000000000000001067 103.0
HFD2_k127_5468133_81 Putative addiction module component - - - 0.0000000000000000000002328 98.0
HFD2_k127_5468133_82 - - - - 0.0000000000000000000004554 108.0
HFD2_k127_5468133_83 - - - - 0.000000000000000000001174 100.0
HFD2_k127_5468133_84 Protein of unknown function DUF86 - - - 0.000000000000000000002802 98.0
HFD2_k127_5468133_85 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000003311 105.0
HFD2_k127_5468133_86 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000000000000001 99.0
HFD2_k127_5468133_87 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000000006097 84.0
HFD2_k127_5468133_88 regulation of single-species biofilm formation K13572 - - 0.0000000000007519 73.0
HFD2_k127_5468133_89 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000002149 65.0
HFD2_k127_5468133_9 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 540.0
HFD2_k127_5468133_91 - K02009 - - 0.00002069 51.0
HFD2_k127_5468133_92 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0005064 46.0
HFD2_k127_5468133_93 META domain K03668 - - 0.0008329 48.0
HFD2_k127_547060_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01576,K01652 - 2.2.1.6,4.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003181 601.0
HFD2_k127_547060_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01576,K01652 - 2.2.1.6,4.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007494 439.0
HFD2_k127_547060_2 general L-amino acid-binding periplasmic protein AapJ K09969 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 295.0
HFD2_k127_547060_3 Flavin containing amine oxidoreductase K00274,K21639 - 1.4.3.25,1.4.3.4 0.000000000000000000000000000000000000000000000000000000000000000234 239.0
HFD2_k127_547060_4 - - - - 0.0000000000000000000000000008126 118.0
HFD2_k127_547060_5 - - - - 0.000000000000000007895 95.0
HFD2_k127_547060_6 Cytochrome c K17760 - 1.1.9.1 0.0000000000000166 78.0
HFD2_k127_547060_8 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000005923 55.0
HFD2_k127_5484932_0 ATP dependent DNA ligase C terminal region K01971 - 6.5.1.1 1.576e-304 956.0
HFD2_k127_5484932_1 - - - - 8.499e-278 871.0
HFD2_k127_5484932_10 Cupin domain K00450 - 1.13.11.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005391 406.0
HFD2_k127_5484932_11 4,5-dihydroxyphthalate decarboxylase K04102 - 4.1.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009887 364.0
HFD2_k127_5484932_12 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 371.0
HFD2_k127_5484932_13 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000589 338.0
HFD2_k127_5484932_14 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 336.0
HFD2_k127_5484932_15 Uncharacterised MFS-type transporter YbfB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006629 311.0
HFD2_k127_5484932_16 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000781 275.0
HFD2_k127_5484932_17 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002524 262.0
HFD2_k127_5484932_18 Belongs to the alpha-IPM synthase homocitrate synthase family K10977 - 2.3.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000008545 259.0
HFD2_k127_5484932_19 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000001414 235.0
HFD2_k127_5484932_2 DNA topological change K03168 - 5.99.1.2 2.734e-237 759.0
HFD2_k127_5484932_20 Ankyrin repeat - - - 0.0000000000000000000000000000000000000000000000000008223 203.0
HFD2_k127_5484932_21 o-linked GlcNac transferase - - - 0.0000000000000000000000000000000000000000006048 172.0
HFD2_k127_5484932_22 Alpha/beta hydrolase family K07020 - - 0.00000000000000000000000000000000000005858 156.0
HFD2_k127_5484932_23 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.00000000000000000000000000000000000008681 154.0
HFD2_k127_5484932_24 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000455 154.0
HFD2_k127_5484932_25 PFAM Uncharacterised protein family (UPF0153) - - - 0.0000000000000000000000000000000009234 149.0
HFD2_k127_5484932_27 metal cluster binding - - - 0.00000000000000000000000001519 117.0
HFD2_k127_5484932_28 - - - - 0.0000000000000000000006258 108.0
HFD2_k127_5484932_29 - - - - 0.000000000000000000003901 99.0
HFD2_k127_5484932_3 PQQ enzyme repeat K00114 - 1.1.2.8 2.465e-229 724.0
HFD2_k127_5484932_30 Metallo-beta-lactamase superfamily - - - 0.00000000000000001461 94.0
HFD2_k127_5484932_31 Protein of unknown function (DUF3311) - - - 0.0000000000000001115 84.0
HFD2_k127_5484932_32 Haem-degrading K11477 - - 0.00000003676 63.0
HFD2_k127_5484932_33 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000001228 62.0
HFD2_k127_5484932_34 Haem-degrading - - - 0.000607 47.0
HFD2_k127_5484932_35 PFAM Glyoxalase bleomycin resistance protein dioxygenase - GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0050896 - 0.0007342 50.0
HFD2_k127_5484932_4 Sodium:solute symporter family K03307 - - 1.692e-207 657.0
HFD2_k127_5484932_5 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K07303 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 608.0
HFD2_k127_5484932_6 transporter K08369 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002801 588.0
HFD2_k127_5484932_7 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006295 508.0
HFD2_k127_5484932_8 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 503.0
HFD2_k127_5484932_9 FAD binding domain K00480,K22270 - 1.14.13.1,1.14.13.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004461 466.0
HFD2_k127_5505528_0 Belongs to the ABC transporter superfamily K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 356.0
HFD2_k127_5505528_1 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003574 258.0
HFD2_k127_5505528_2 Helix-turn-helix domain, rpiR family - - - 0.0000000000000000000000000002232 122.0
HFD2_k127_5519362_0 lactate metabolic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009051 516.0
HFD2_k127_5519362_1 FAD dependent oxidoreductase K13796 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000504 276.0
HFD2_k127_5519362_2 general secretion pathway protein K02461 - - 0.000000000000000000000000747 117.0
HFD2_k127_5519362_3 General secretion pathway protein M K02462 - - 0.0000001307 61.0
HFD2_k127_5519362_4 - K02463 - - 0.0000003973 60.0
HFD2_k127_5563446_0 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000001218 179.0
HFD2_k127_5563446_1 - - - - 0.000000000000000000000000000002451 128.0
HFD2_k127_5563446_2 RHS Repeat - - - 0.00000000000000000000000000000373 128.0
HFD2_k127_5563446_3 COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein K04768 - - 0.0000000000000000000001271 99.0
HFD2_k127_5563446_5 Membrane transport protein K07088 - - 0.000008339 52.0
HFD2_k127_5593791_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005631 565.0
HFD2_k127_5593791_1 phosphoglycolate phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 309.0
HFD2_k127_5593791_2 Methyltransferase domain - - - 0.0000000009356 60.0
HFD2_k127_5593791_3 - - - - 0.0002932 45.0
HFD2_k127_5627643_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006181 358.0
HFD2_k127_5627643_1 FMN_bind - - - 0.00000000000000000000000000000000000000000000000000000000000000003025 228.0
HFD2_k127_5627643_2 - - - - 0.0000000000000000000000000000000000000000000000000000000002575 216.0
HFD2_k127_5627643_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000107 95.0
HFD2_k127_5627643_4 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000009157 67.0
HFD2_k127_5629696_1 ABC-type Fe3 transport system permease component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 471.0
HFD2_k127_5629696_2 Major Facilitator Superfamily K13021 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 409.0
HFD2_k127_5629696_3 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007717 329.0
HFD2_k127_5629696_4 Sugar (and other) transporter K08195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007853 327.0
HFD2_k127_5629696_5 acetyl-coa acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003624 284.0
HFD2_k127_5629696_6 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.000000000000000000000000000000000559 139.0
HFD2_k127_5629696_7 PRC-barrel domain - - - 0.0001312 50.0
HFD2_k127_5658196_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 1.808e-242 762.0
HFD2_k127_5658196_1 SMP-30/Gluconolaconase/LRE-like region K14274 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003811 445.0
HFD2_k127_5658196_2 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000001496 206.0
HFD2_k127_5658196_3 - - - - 0.000000000000000000000004732 114.0
HFD2_k127_5658196_4 Tetratricopeptide repeat - - - 0.00000000000000001081 93.0
HFD2_k127_5658196_5 lactate metabolic process - - - 0.000000000000001517 79.0
HFD2_k127_5660208_0 receptor - - - 1.172e-320 1002.0
HFD2_k127_5660208_1 Glycosyl transferase family 41 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 535.0
HFD2_k127_5660208_10 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000001613 186.0
HFD2_k127_5660208_11 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000008698 188.0
HFD2_k127_5660208_12 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000003 178.0
HFD2_k127_5660208_14 - - - - 0.0000001182 58.0
HFD2_k127_5660208_15 Nickel/cobalt transporter regulator - - - 0.000004384 54.0
HFD2_k127_5660208_2 peptidase dimerisation domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 489.0
HFD2_k127_5660208_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00836 - 2.6.1.76 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000414 412.0
HFD2_k127_5660208_4 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 375.0
HFD2_k127_5660208_5 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000207 241.0
HFD2_k127_5660208_6 Uncharacterized protein conserved in bacteria (DUF2239) K09965 - - 0.00000000000000000000000000000000000000000000000000000000000000004654 228.0
HFD2_k127_5660208_7 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000001829 232.0
HFD2_k127_5660208_8 Protein of unknown function (DUF2914) - - - 0.000000000000000000000000000000000000000000000000000002468 205.0
HFD2_k127_5660208_9 Twin-arginine translocation pathway signal protein - - - 0.0000000000000000000000000000000000000000000000000000409 193.0
HFD2_k127_5680507_0 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 418.0
HFD2_k127_5680507_1 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 292.0
HFD2_k127_5680507_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007318 267.0
HFD2_k127_5680507_3 Purine catabolism regulatory protein-like family K09684 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006892 273.0
HFD2_k127_5731569_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1189.0
HFD2_k127_5731569_1 Serine protein kinase K07180 - - 0.0 1095.0
HFD2_k127_5731569_10 Transcriptional regulatory protein, C terminal K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007342 376.0
HFD2_k127_5731569_11 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 373.0
HFD2_k127_5731569_12 Belongs to the peptidase M20A family. ArgE subfamily K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009776 366.0
HFD2_k127_5731569_13 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005411 356.0
HFD2_k127_5731569_14 signal transduction histidine kinase K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 334.0
HFD2_k127_5731569_15 O-linked N-acetylglucosamine transferase SPINDLY family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 342.0
HFD2_k127_5731569_16 GTP cyclohydrolase K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 304.0
HFD2_k127_5731569_17 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 289.0
HFD2_k127_5731569_18 Fatty acid desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008684 284.0
HFD2_k127_5731569_19 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001587 276.0
HFD2_k127_5731569_2 SpoVR like protein K06415 - - 5.06e-202 639.0
HFD2_k127_5731569_20 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000722 253.0
HFD2_k127_5731569_21 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.0000000000000000000000000000000000000000000000000000000000000001495 232.0
HFD2_k127_5731569_22 redox protein regulator of disulfide bond formation - - - 0.000000000000000000000000000000000000000000000003713 179.0
HFD2_k127_5731569_23 protein affecting Mg2 Co2 transport K06195 - - 0.00000000000000000000000000000000000000000000005554 175.0
HFD2_k127_5731569_24 GcrA cell cycle regulator K13583 - - 0.000000000000000000000000000000000000000000005017 169.0
HFD2_k127_5731569_25 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000005278 169.0
HFD2_k127_5731569_26 methyltransferase activity - - - 0.00000000000000000000000000000000000000000001055 168.0
HFD2_k127_5731569_27 polysaccharide biosynthetic process K19431 - - 0.000000000000000000000000000000000000000001103 175.0
HFD2_k127_5731569_28 FR47-like protein - - - 0.0000000000000000000000000000000000009703 145.0
HFD2_k127_5731569_29 phosphohistidine phosphatase K08296 - - 0.00000000000000000000000000000000001109 143.0
HFD2_k127_5731569_3 Aminotransferase class-III K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003347 544.0
HFD2_k127_5731569_30 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000003921 121.0
HFD2_k127_5731569_31 AntiSigma factor - - - 0.000000000000000000000000005954 120.0
HFD2_k127_5731569_32 Cell Wall Hydrolase - - - 0.0000000000000000000000002577 109.0
HFD2_k127_5731569_33 - - - - 0.00000008406 56.0
HFD2_k127_5731569_34 COG0457 FOG TPR repeat - - - 0.000007232 57.0
HFD2_k127_5731569_4 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004509 504.0
HFD2_k127_5731569_5 Belongs to the UPF0229 family K09786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009513 496.0
HFD2_k127_5731569_6 belongs to the carbohydrate kinase PfkB family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 466.0
HFD2_k127_5731569_7 outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 456.0
HFD2_k127_5731569_8 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009508 444.0
HFD2_k127_5731569_9 Phage P22-like portal protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 449.0
HFD2_k127_5750211_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 586.0
HFD2_k127_5750211_1 Dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000912 604.0
HFD2_k127_5750211_2 Protein conserved in bacteria - - - 0.000000000000000000000000005263 115.0
HFD2_k127_5750211_3 positive regulation of growth - - - 0.000000000000000003354 86.0
HFD2_k127_5750211_5 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000002896 62.0
HFD2_k127_5750211_6 PFAM Integrase catalytic region K00986 - 2.7.7.49 0.00000003618 58.0
HFD2_k127_5753734_0 MmgE/PrpD family K01720 - 4.2.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 477.0
HFD2_k127_5753734_1 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 296.0
HFD2_k127_5753734_2 sequence-specific DNA binding K05800 - - 0.000000000000000000000000000000000000000000000000000000000005957 211.0
HFD2_k127_5753734_3 Bacterial extracellular solute-binding protein K02020,K22003 - 5.3.3.7 0.000000000000000000000000000000000001716 147.0
HFD2_k127_5753734_4 cytochrome - - - 0.00000000000000000000000000000002796 139.0
HFD2_k127_5753734_5 response to abiotic stimulus - - - 0.000000000000000000000000001837 118.0
HFD2_k127_5753734_6 - - - - 0.00000000000000000000000004538 119.0
HFD2_k127_5753734_7 - - - - 0.00000000000000000000001122 111.0
HFD2_k127_5753734_8 - - - - 0.0000000000000000000109 108.0
HFD2_k127_5764350_0 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000001424 155.0
HFD2_k127_5764350_1 - - - - 0.0000000000000000000000000000000000002005 153.0
HFD2_k127_5764350_2 SMART AAA ATPase - - - 0.0000000000000000000000000000006041 124.0
HFD2_k127_5846323_0 DNA polymerase IV K02346 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 491.0
HFD2_k127_5846323_1 Belongs to the ABC transporter superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 482.0
HFD2_k127_5846323_11 - - - - 0.000000000002035 70.0
HFD2_k127_5846323_12 DoxX-like family - - - 0.000001195 57.0
HFD2_k127_5846323_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004868 281.0
HFD2_k127_5846323_3 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005693 288.0
HFD2_k127_5846323_4 Crp-like helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001153 254.0
HFD2_k127_5846323_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006143 252.0
HFD2_k127_5846323_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009222 249.0
HFD2_k127_5846323_7 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000002604 185.0
HFD2_k127_5846323_8 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.000000000000000000000000000000000000000001445 158.0
HFD2_k127_5846323_9 SMART Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000003771 147.0
HFD2_k127_5872860_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 9.237e-297 927.0
HFD2_k127_5872860_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.832e-258 816.0
HFD2_k127_5872860_10 Hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 344.0
HFD2_k127_5872860_11 Peptidase S24-like K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 341.0
HFD2_k127_5872860_12 COG2041 Sulfite oxidase and related enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009422 329.0
HFD2_k127_5872860_13 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008417 307.0
HFD2_k127_5872860_14 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 292.0
HFD2_k127_5872860_15 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 286.0
HFD2_k127_5872860_16 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002006 283.0
HFD2_k127_5872860_17 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000006727 266.0
HFD2_k127_5872860_18 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000003466 264.0
HFD2_k127_5872860_19 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000001383 247.0
HFD2_k127_5872860_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 3.446e-226 711.0
HFD2_k127_5872860_20 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000008045 227.0
HFD2_k127_5872860_21 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.000000000000000000000000000000000000000000000000000000000001123 213.0
HFD2_k127_5872860_22 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000007721 201.0
HFD2_k127_5872860_23 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000000000000000000000000000001187 188.0
HFD2_k127_5872860_24 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000000000004315 189.0
HFD2_k127_5872860_25 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.00000000000000000000000000000000000000000001698 166.0
HFD2_k127_5872860_26 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000000000007456 128.0
HFD2_k127_5872860_27 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.0000000000000000000000000000003359 138.0
HFD2_k127_5872860_28 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000009527 123.0
HFD2_k127_5872860_29 Putative DNA-binding domain - - - 0.0000000000000000000000000004247 127.0
HFD2_k127_5872860_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 3.925e-221 696.0
HFD2_k127_5872860_30 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.000000000000000000000001901 106.0
HFD2_k127_5872860_31 AraC-like ligand binding domain - - - 0.00000000000000000000005705 103.0
HFD2_k127_5872860_32 Glycosyltransferase family 25 (LPS biosynthesis protein) - - - 0.000000000000000000002629 104.0
HFD2_k127_5872860_33 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000001266 91.0
HFD2_k127_5872860_4 COG1960 Acyl-CoA dehydrogenases K09456 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 604.0
HFD2_k127_5872860_5 Transglycosylase SLT domain K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004741 464.0
HFD2_k127_5872860_6 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 GO:0003674,GO:0003824,GO:0006082,GO:0006090,GO:0008150,GO:0008152,GO:0008840,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044281,GO:0071704 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007371 414.0
HFD2_k127_5872860_7 Rossmann fold nucleotide-binding protein involved in DNA uptake K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 396.0
HFD2_k127_5872860_8 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 399.0
HFD2_k127_5872860_9 PFAM Glutathione S-transferase domain K11209 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 368.0
HFD2_k127_5954993_0 PA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006489 554.0
HFD2_k127_5954993_1 Methionine aminopeptidase K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004226 413.0
HFD2_k127_5954993_2 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009601 307.0
HFD2_k127_5954993_3 molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 287.0
HFD2_k127_5954993_4 Phosphatidylethanolamine-binding protein K06910 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000001294 197.0
HFD2_k127_5954993_5 Periplasmic component of the Tol biopolymer transport system K03641 - - 0.00000000000000000000000000000000000000000001641 173.0
HFD2_k127_5954993_6 Cytochrome c-type biogenesis protein K02200 - - 0.00000000000000000000000000000001526 138.0
HFD2_k127_5961855_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 0.0 1131.0
HFD2_k127_5961855_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1078.0
HFD2_k127_5961855_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 355.0
HFD2_k127_5961855_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001345 267.0
HFD2_k127_5961855_12 Copper resistance protein B precursor (CopB) K07233 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003307 258.0
HFD2_k127_5961855_13 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000008675 237.0
HFD2_k127_5961855_14 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.000000000000000000000000000000000000000000000000000001176 198.0
HFD2_k127_5961855_15 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000000000000001759 162.0
HFD2_k127_5961855_16 LTXXQ motif family protein - - - 0.00000000000000000000000000000000000000000606 162.0
HFD2_k127_5961855_17 Heavy-metal resistance - - - 0.000000000000000000000000000000001116 134.0
HFD2_k127_5961855_18 Protein of unknown function (DUF2933) - - - 0.0000000000000000000001271 99.0
HFD2_k127_5961855_19 - - - - 0.00000000000000000004749 97.0
HFD2_k127_5961855_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.071e-261 819.0
HFD2_k127_5961855_20 Copper resistance protein K07156 - - 0.0000000000002788 75.0
HFD2_k127_5961855_21 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific - - - 0.000000003965 63.0
HFD2_k127_5961855_22 Recombinase - - - 0.0008836 48.0
HFD2_k127_5961855_3 Multicopper oxidase - - - 8.94e-220 699.0
HFD2_k127_5961855_4 exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 2.411e-200 632.0
HFD2_k127_5961855_5 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 512.0
HFD2_k127_5961855_6 S-adenosylmethionine synthetase (AdoMet synthetase) K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 499.0
HFD2_k127_5961855_7 TIGRFAM Glyceraldehyde-3-phosphate dehydrogenase, type II K00150 - 1.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007867 440.0
HFD2_k127_5961855_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008785 429.0
HFD2_k127_5961855_9 Isoprenylcysteine carboxyl methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 383.0
HFD2_k127_6005078_0 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins K03466 - - 1.292e-238 763.0
HFD2_k127_6005078_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 542.0
HFD2_k127_6005078_10 TIGRFAM acyl-CoA thioesterase II K10805 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016042,GO:0016054,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042802,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072329,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 369.0
HFD2_k127_6005078_11 Putative Flp pilus-assembly TadE/G-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005122 293.0
HFD2_k127_6005078_12 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000008614 200.0
HFD2_k127_6005078_13 Methylase involved in ubiquinone menaquinone biosynthesis K13623 - - 0.00000000000000000000000000000000000000000000000000007547 201.0
HFD2_k127_6005078_14 Nitrogen regulatory protein P-II - - - 0.00000000000000000000000000000000000000000000000001607 182.0
HFD2_k127_6005078_15 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000009987 142.0
HFD2_k127_6005078_16 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000005802 128.0
HFD2_k127_6005078_17 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.0000000000000000000000000000001185 126.0
HFD2_k127_6005078_18 Bacterial PH domain - - - 0.000000000000000000000000000008855 124.0
HFD2_k127_6005078_19 Protein conserved in bacteria - - - 0.00000000000000000000000004068 111.0
HFD2_k127_6005078_2 ammonium transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008842 540.0
HFD2_k127_6005078_20 Protein of unknown function (DUF1778) - - - 0.000000000000000000000006579 105.0
HFD2_k127_6005078_21 CopG antitoxin of type II toxin-antitoxin system - - - 0.0000000000000000002499 91.0
HFD2_k127_6005078_22 - - - - 0.000000000000001557 85.0
HFD2_k127_6005078_23 Glycosyltransferase family 87 - - - 0.0000000006915 65.0
HFD2_k127_6005078_24 TadE-like protein - - - 0.0000008108 58.0
HFD2_k127_6005078_25 TadE-like protein - - - 0.00003173 55.0
HFD2_k127_6005078_3 FAD binding domain K03185 GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016491,GO:0019168,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901576,GO:1901661,GO:1901663 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 485.0
HFD2_k127_6005078_4 Protein of unknown function (DUF3419) K13622 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 445.0
HFD2_k127_6005078_5 3-hydroxyacyl-coa dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008947 438.0
HFD2_k127_6005078_6 Electron transfer flavoprotein domain K03522 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 397.0
HFD2_k127_6005078_7 Aminotransferase class I and II K14261,K14267 - 2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004122 389.0
HFD2_k127_6005078_8 Electron transfer flavoprotein domain K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 365.0
HFD2_k127_6005078_9 AFG1-like ATPase K06916 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0006091,GO:0006119,GO:0006123,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007005,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0017144,GO:0019538,GO:0019637,GO:0019646,GO:0019693,GO:0022900,GO:0022904,GO:0030163,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0035694,GO:0042773,GO:0042775,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071840,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 371.0
HFD2_k127_6065188_0 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 400.0
HFD2_k127_6065188_1 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 381.0
HFD2_k127_6065188_10 hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000006265 163.0
HFD2_k127_6065188_11 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000001387 169.0
HFD2_k127_6065188_12 - - - - 0.000000000000000000000000000000000000007722 154.0
HFD2_k127_6065188_13 - - - - 0.00000000000000000000000000000002994 140.0
HFD2_k127_6065188_14 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000006229 114.0
HFD2_k127_6065188_15 - - - - 0.0000000000000000000000002053 117.0
HFD2_k127_6065188_17 - - - - 0.0000000000000000002696 99.0
HFD2_k127_6065188_18 - - - - 0.000000000000000001135 92.0
HFD2_k127_6065188_19 - - - - 0.00000000000000002387 93.0
HFD2_k127_6065188_2 Major Facilitator Superfamily K13021 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007019 382.0
HFD2_k127_6065188_22 Cupin - - - 0.000000131 54.0
HFD2_k127_6065188_23 - - - - 0.000004834 56.0
HFD2_k127_6065188_24 transport - - - 0.0001157 50.0
HFD2_k127_6065188_3 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 324.0
HFD2_k127_6065188_4 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002508 264.0
HFD2_k127_6065188_5 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004679 248.0
HFD2_k127_6065188_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000303 253.0
HFD2_k127_6065188_7 cytochrome - - - 0.00000000000000000000000000000000000000000000000000000005046 209.0
HFD2_k127_6065188_8 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000000003248 186.0
HFD2_k127_6065188_9 Domain of unknown function (DUF4142) K08995 - - 0.0000000000000000000000000000000000000000000000000327 188.0
HFD2_k127_6098827_0 Protein of unknown function (DUF1343) - - - 8.725e-225 707.0
HFD2_k127_6098827_1 ethanolamine utilization protein K04019 GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0030091,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009,GO:0071704,GO:1901564 - 2.02e-219 694.0
HFD2_k127_6098827_10 integral membrane protein - - - 0.000000000007603 71.0
HFD2_k127_6098827_2 - - - - 6.648e-200 627.0
HFD2_k127_6098827_3 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 376.0
HFD2_k127_6098827_4 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004928 299.0
HFD2_k127_6098827_5 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 302.0
HFD2_k127_6098827_6 - - - - 0.00000000000000000000000000000000000000000009351 165.0
HFD2_k127_6098827_7 - - - - 0.000000000000000000000000001044 117.0
HFD2_k127_6098827_8 Helix-turn-helix domain - - - 0.000000000000000000003294 98.0
HFD2_k127_6098827_9 - - - - 0.0000000000000000001734 96.0
HFD2_k127_6142158_0 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 567.0
HFD2_k127_6142158_1 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009058 546.0
HFD2_k127_6142158_2 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 367.0
HFD2_k127_6142158_3 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009361 264.0
HFD2_k127_6142158_4 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.0000000000000000000000000000000000000000000000000000000000000000001519 239.0
HFD2_k127_6142158_5 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000001371 214.0
HFD2_k127_6142158_6 Catalyzes the reduction of tatronate semialdehyde to D- glycerate K00020,K00042 GO:0003674,GO:0003824,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0008679,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0019392,GO:0019394,GO:0019577,GO:0019579,GO:0019580,GO:0019752,GO:0042737,GO:0042836,GO:0042838,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046392,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000000000000000007189 184.0
HFD2_k127_6142158_7 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000000001117 112.0
HFD2_k127_6142158_8 Asp/Glu/Hydantoin racemase K01799 - 5.2.1.1 0.000000000000000000009362 101.0
HFD2_k127_6165988_0 ATP corrinoid adenosyltransferase K19221 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000001816 211.0
HFD2_k127_6165988_1 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.00001271 48.0
HFD2_k127_6165988_2 - - - - 0.0001301 52.0
HFD2_k127_6216254_0 - - - - 0.000000000000000003371 100.0
HFD2_k127_6230501_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000002475 149.0
HFD2_k127_6230501_1 Homeodomain-like domain - - - 0.000000000000000227 81.0
HFD2_k127_6230501_2 Homeodomain-like domain - - - 0.000000000005245 74.0
HFD2_k127_6230501_3 - - - - 0.00000000004313 68.0
HFD2_k127_624403_0 FAD dependent oxidoreductase - - - 4.921e-240 752.0
HFD2_k127_624403_1 Tripartite tricarboxylate transporter TctA family - - - 6.365e-212 678.0
HFD2_k127_624403_10 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 380.0
HFD2_k127_624403_11 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007376 386.0
HFD2_k127_624403_12 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 324.0
HFD2_k127_624403_13 Dihydroorotate dehydrogenase K17723 - 1.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 319.0
HFD2_k127_624403_14 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 309.0
HFD2_k127_624403_15 Adenylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001312 301.0
HFD2_k127_624403_16 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003127 285.0
HFD2_k127_624403_17 Oxidoreductase, FAD-binding K02823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003131 276.0
HFD2_k127_624403_18 Nitrile hydratase K01721,K20807 - 4.2.1.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000008228 267.0
HFD2_k127_624403_19 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000009638 273.0
HFD2_k127_624403_2 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 534.0
HFD2_k127_624403_20 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003227 254.0
HFD2_k127_624403_21 OsmC-like protein K07397 - - 0.00000000000000000000000000000000000000000000000000000000000000000003044 233.0
HFD2_k127_624403_22 Auxin binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000003195 234.0
HFD2_k127_624403_23 domain, Protein K01179 - 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000002605 237.0
HFD2_k127_624403_24 [2Fe-2S] binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000004965 234.0
HFD2_k127_624403_25 Metal-dependent hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000221 227.0
HFD2_k127_624403_26 Carbon monoxide dehydrogenase subunit G (CoxG) - - - 0.000000000000000000000000000000000000000000000000000378 190.0
HFD2_k127_624403_27 - K06992 - - 0.00000000000000000000000000000000000000000000000002962 188.0
HFD2_k127_624403_28 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000006842 175.0
HFD2_k127_624403_29 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000007852 155.0
HFD2_k127_624403_3 TIGRFAM metabolite H symporter, major facilitator superfamily (MFS) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 514.0
HFD2_k127_624403_30 PFAM NUDIX hydrolase K03574 - 3.6.1.55 0.0000000000000000000000000000000255 132.0
HFD2_k127_624403_31 Protein of Unknown function (DUF2784) - - - 0.0000000000000000000000000000009651 129.0
HFD2_k127_624403_32 Nitrile hydratase beta subunit K20807 - 4.2.1.84 0.0000000000000000000000000004759 115.0
HFD2_k127_624403_33 - - - - 0.0000000000000000000000000005232 124.0
HFD2_k127_624403_34 - - - - 0.000000000000001436 87.0
HFD2_k127_624403_35 - - - - 0.00000000005419 74.0
HFD2_k127_624403_36 glyoxalase K07104 - 1.13.11.2 0.0000004479 58.0
HFD2_k127_624403_4 TIGRFAM metabolite H symporter, major facilitator superfamily (MFS) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000502 481.0
HFD2_k127_624403_5 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate K01612,K03182,K16874 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044464 4.1.1.61,4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 445.0
HFD2_k127_624403_6 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008164 416.0
HFD2_k127_624403_7 of the major facilitator superfamily K03288 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 417.0
HFD2_k127_624403_8 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003822 426.0
HFD2_k127_624403_9 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003643 399.0
HFD2_k127_627450_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000003736 239.0
HFD2_k127_627450_1 ETC complex I subunit conserved region K00329 - 1.6.5.3 0.000000000000000000000000000000000000000005366 158.0
HFD2_k127_627450_2 - - - - 0.00000000000000000000000000004142 130.0
HFD2_k127_627450_3 endonuclease K07451 - - 0.00002651 53.0
HFD2_k127_6300123_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000691 579.0
HFD2_k127_6300123_1 PFAM aminotransferase class V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 424.0
HFD2_k127_6300123_2 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002784 255.0
HFD2_k127_6300123_3 Carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000003809 241.0
HFD2_k127_6300123_4 - - - - 0.00000000000000000000000000000000000009893 147.0
HFD2_k127_6300123_5 Formate-dependent nitrite reductase, membrane - - - 0.0000000000000000000000000000000000005091 147.0
HFD2_k127_6300123_6 sulfur relay protein, TusE DsrC DsvC family K11179 - - 0.000000000000000000000000000000000006008 138.0
HFD2_k127_6300123_7 Protein of unknown function (DUF3343) - - - 0.000000000000000000000000000000001299 137.0
HFD2_k127_6300123_8 Sulphur transport K07112 - - 0.00000000000000000000000000003062 126.0
HFD2_k127_6300355_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032940,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 619.0
HFD2_k127_6300355_1 protein N-acetylglucosaminyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 617.0
HFD2_k127_6300355_10 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004247 378.0
HFD2_k127_6300355_11 Prephenate dehydratase K04518 - 4.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 359.0
HFD2_k127_6300355_12 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 346.0
HFD2_k127_6300355_13 Uncharacterised protein conserved in bacteria (DUF2336) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007568 349.0
HFD2_k127_6300355_14 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000416 323.0
HFD2_k127_6300355_15 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 306.0
HFD2_k127_6300355_16 NADH pyrophosphatase-like rudimentary NUDIX domain K03426 - 3.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008437 276.0
HFD2_k127_6300355_17 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001414 267.0
HFD2_k127_6300355_18 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001417 253.0
HFD2_k127_6300355_19 trans-aconitate K00598 - 2.1.1.144 0.0000000000000000000000000000000000000000000000000000000000000000000006548 246.0
HFD2_k127_6300355_2 Glycosyl transferase family 41 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009874 580.0
HFD2_k127_6300355_20 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01450,K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.31,3.5.1.88 0.00000000000000000000000000000000000000000000000000000002664 201.0
HFD2_k127_6300355_21 Macro domain protein - - - 0.0000000000000000000000000000000000000000000000009579 179.0
HFD2_k127_6300355_22 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000004105 173.0
HFD2_k127_6300355_23 Methyltransferase domain - - - 0.000000000000000000000000000000000000000001113 166.0
HFD2_k127_6300355_24 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000000000000004339 109.0
HFD2_k127_6300355_25 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000004446 102.0
HFD2_k127_6300355_26 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000178 90.0
HFD2_k127_6300355_27 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000000001162 72.0
HFD2_k127_6300355_28 - - - - 0.000000001998 61.0
HFD2_k127_6300355_3 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 574.0
HFD2_k127_6300355_30 - - - - 0.0003959 49.0
HFD2_k127_6300355_31 - - - - 0.0009107 52.0
HFD2_k127_6300355_4 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 456.0
HFD2_k127_6300355_5 PFAM transferase hexapeptide repeat containing protein K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 415.0
HFD2_k127_6300355_6 protein N-acetylglucosaminyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008588 414.0
HFD2_k127_6300355_7 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 412.0
HFD2_k127_6300355_8 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004389 394.0
HFD2_k127_6300355_9 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003651 388.0
HFD2_k127_6302373_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 2.678e-243 794.0
HFD2_k127_6302373_1 Putative modulator of DNA gyrase K03568 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 2.609e-196 616.0
HFD2_k127_6302373_2 COG3264 Small-conductance mechanosensitive channel K05802 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009957 347.0
HFD2_k127_6302373_3 - - - - 0.000000000001463 72.0
HFD2_k127_6302373_4 Plasmid maintenance protein CcdB K19163 - - 0.00000007376 56.0
HFD2_k127_6313794_0 Metal dependent phosphohydrolases with conserved 'HD' motif. K00990 GO:0006355,GO:0006464,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0009605,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0018175,GO:0018177,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:1901564,GO:1901698,GO:1901699,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.7.7.59 4.52e-321 1009.0
HFD2_k127_6313794_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009380,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 3.035e-256 804.0
HFD2_k127_6313794_10 imidazolonepropionase activity - - - 0.000000000000000000000000000000000000000000000000000001193 210.0
HFD2_k127_6313794_11 Molybdopterin converting factor, large subunit K03635 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000001437 195.0
HFD2_k127_6313794_12 Adenylate cyclase - - - 0.00000000000000000000000000000000000000000000000000005253 206.0
HFD2_k127_6313794_13 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.0000000000000000000000000000000000000000000000000000985 192.0
HFD2_k127_6313794_14 arsenate reductase K00537 - 1.20.4.1 0.0000000000000000000000000000000000000004073 151.0
HFD2_k127_6313794_15 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000000000000000000000000000000000003514 147.0
HFD2_k127_6313794_16 CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000000000002231 124.0
HFD2_k127_6313794_17 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000009875 111.0
HFD2_k127_6313794_18 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.000000000000000000000177 108.0
HFD2_k127_6313794_19 Cold shock K03704 - - 0.0000000000000000000006331 99.0
HFD2_k127_6313794_2 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005841 558.0
HFD2_k127_6313794_20 Dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000005079 100.0
HFD2_k127_6313794_21 - - - - 0.00000000000003669 81.0
HFD2_k127_6313794_22 - - - - 0.000000000000203 76.0
HFD2_k127_6313794_23 positive regulation of growth K07746 - - 0.0003798 44.0
HFD2_k127_6313794_3 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 497.0
HFD2_k127_6313794_4 Amidase K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004875 496.0
HFD2_k127_6313794_5 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 342.0
HFD2_k127_6313794_6 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 286.0
HFD2_k127_6313794_7 antibiotic catabolic process K13277,K20276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005279 291.0
HFD2_k127_6313794_8 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000004108 246.0
HFD2_k127_6313794_9 Feruloyl esterase - - - 0.000000000000000000000000000000000000000000000000000000001019 208.0
HFD2_k127_633618_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01576,K01652 - 2.2.1.6,4.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007124 587.0
HFD2_k127_633618_1 Amidase K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 535.0
HFD2_k127_633618_2 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 484.0
HFD2_k127_633618_3 Amidohydrolase K03392 - 4.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 435.0
HFD2_k127_633618_4 Nitrile hydratase K01721 - 4.2.1.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 329.0
HFD2_k127_633618_5 N-acetyltransferase K00675 - 2.3.1.118 0.000000000000000000000000000000000000000000000000000000000000000000000000002151 262.0
HFD2_k127_633618_6 NHase catalyzes the hydration of various nitrile compounds to the corresponding amides K20807 - 4.2.1.84 0.0000000000000000000000000000000000000000000000000000000000000000000004397 245.0
HFD2_k127_633618_7 Histidine kinase K07716 - 2.7.13.3 0.00000000000000000000000000000000000000000000003627 177.0
HFD2_k127_633618_8 Nitrile hydratase - - - 0.00000000000000000000000000000000003568 139.0
HFD2_k127_633618_9 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000001724 81.0
HFD2_k127_6345126_0 Adenylate and Guanylate cyclase catalytic domain - - - 3.871e-226 742.0
HFD2_k127_6345126_1 Adenylate cyclase - - - 0.000000000000000000000000000000007994 149.0
HFD2_k127_6384530_0 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002145 282.0
HFD2_k127_6384530_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003511 273.0
HFD2_k127_6384530_2 Protein of unknown function (DUF992) - - - 0.00000000000000000000000000000000007753 138.0
HFD2_k127_6384530_3 Domain of unknown function (DUF4189) - - - 0.0000000004128 67.0
HFD2_k127_6419440_0 FAD linked oxidases, C-terminal domain - - - 0.0 1422.0
HFD2_k127_6419440_1 TIGRFAM L-lactate transport K03303 - - 3.244e-240 761.0
HFD2_k127_6419440_10 pilus organization - - - 0.000000000000000000000000000000000000000000000000000000000000000005552 259.0
HFD2_k127_6419440_11 YCII-related domain - - - 0.0000000000000000000000000000000000000000000000000003434 189.0
HFD2_k127_6419440_12 Protein of unknown function (DUF559) - - - 0.000000000000000000000000000000003861 132.0
HFD2_k127_6419440_13 - - - - 0.00000000000000000000004798 109.0
HFD2_k127_6419440_14 Domain of unknown function (DUF4136) - - - 0.00001053 55.0
HFD2_k127_6419440_2 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 2.424e-194 618.0
HFD2_k127_6419440_3 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000308 601.0
HFD2_k127_6419440_4 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 520.0
HFD2_k127_6419440_5 Haemolysin-type calcium binding protein related domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 498.0
HFD2_k127_6419440_6 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005249 391.0
HFD2_k127_6419440_7 Protein of unknown function (Hypoth_ymh) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 353.0
HFD2_k127_6419440_8 FAD binding domain K11472 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002748 277.0
HFD2_k127_6419440_9 3-demethylubiquinone-9 3-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000483 240.0
HFD2_k127_6469035_0 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons - - - 4.783e-238 752.0
HFD2_k127_6469035_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 6.303e-224 702.0
HFD2_k127_6469035_10 PBP superfamily domain K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 433.0
HFD2_k127_6469035_11 ABC transporter K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002323 402.0
HFD2_k127_6469035_12 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006126 397.0
HFD2_k127_6469035_13 phosphate transport system permease K02038 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0010921,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0019220,GO:0019222,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0031323,GO:0033554,GO:0034220,GO:0035303,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051174,GO:0051179,GO:0051234,GO:0051336,GO:0051716,GO:0055085,GO:0065007,GO:0065009,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 375.0
HFD2_k127_6469035_14 Phosphate-selective porin O and P - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003844 376.0
HFD2_k127_6469035_15 Bacterial protein of unknown function (DUF899) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 327.0
HFD2_k127_6469035_16 Acetyltransferase (GNAT) domain K22310 - 2.3.2.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 316.0
HFD2_k127_6469035_17 Chaperone SurA K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000003794 246.0
HFD2_k127_6469035_18 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000000007598 195.0
HFD2_k127_6469035_19 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000005347 189.0
HFD2_k127_6469035_2 PQQ-like domain - - - 1.095e-205 659.0
HFD2_k127_6469035_20 Phosphatidylethanolamine-binding protein K06910 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000004019 178.0
HFD2_k127_6469035_21 Trypsin - - - 0.000000000000000000000000000000000002895 151.0
HFD2_k127_6469035_22 protein conserved in bacteria - - - 0.0000000000000000000000000000000003076 139.0
HFD2_k127_6469035_23 COG1525 Micrococcal nuclease (thermonuclease) homologs - - - 0.000000000000000000000000000000004329 134.0
HFD2_k127_6469035_24 - - - - 0.000000000000000001811 95.0
HFD2_k127_6469035_25 protein conserved in bacteria K09796 - - 0.0000000000000002121 87.0
HFD2_k127_6469035_26 Protein of unknown function (DUF1674) - - - 0.00000000000003794 74.0
HFD2_k127_6469035_27 Hypoxia induced protein conserved region - - - 0.0000002007 55.0
HFD2_k127_6469035_3 major facilitator superfamily K08218 - - 8.261e-204 651.0
HFD2_k127_6469035_4 PFAM aldehyde oxidase and xanthine dehydrogenase a b hammerhead - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 518.0
HFD2_k127_6469035_5 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000767 476.0
HFD2_k127_6469035_6 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005306 473.0
HFD2_k127_6469035_7 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 486.0
HFD2_k127_6469035_8 Binding-protein-dependent transport system inner membrane component K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 441.0
HFD2_k127_6469035_9 Multicopper oxidase K22348 - 1.16.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005801 443.0
HFD2_k127_6503380_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1058.0
HFD2_k127_6503380_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 4.96e-299 927.0
HFD2_k127_6503380_10 ABC transporter permease K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 340.0
HFD2_k127_6503380_11 Mo-co oxidoreductase dimerisation domain K17225 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 344.0
HFD2_k127_6503380_12 L-asparaginase II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003357 302.0
HFD2_k127_6503380_13 ATPases associated with a variety of cellular activities K02003 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 297.0
HFD2_k127_6503380_14 Belongs to the BI1 family K06890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002382 283.0
HFD2_k127_6503380_15 GDSL-like Lipase/Acylhydrolase K10804 - 3.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000008996 248.0
HFD2_k127_6503380_16 SpoU rRNA Methylase family - - - 0.0000000000000000000000000000000000000000000000000000000000000007197 224.0
HFD2_k127_6503380_17 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000001038 222.0
HFD2_k127_6503380_18 Phospholipid N-methyltransferase K00570 - 2.1.1.17,2.1.1.71 0.00000000000000000000000000000000000000000000000001148 186.0
HFD2_k127_6503380_19 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000000000000002372 193.0
HFD2_k127_6503380_2 Belongs to the CarB family K01955 - 6.3.5.5 1.713e-278 866.0
HFD2_k127_6503380_20 Zincin-like metallopeptidase K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000002726 174.0
HFD2_k127_6503380_21 invasion associated locus B - - - 0.0000000000000000000000000000000000000004045 154.0
HFD2_k127_6503380_22 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000000000000000000000000003533 150.0
HFD2_k127_6503380_23 Protein of unknown function (DUF2794) - - - 0.000000000000000000000000000000001318 138.0
HFD2_k127_6503380_24 Cytochrome C oxidase, cbb3-type, subunit III K08738 - - 0.00000000000000000000000000002085 124.0
HFD2_k127_6503380_25 Domain of unknown function (DUF4340) - - - 0.0000000000000000000000000000381 131.0
HFD2_k127_6503380_26 PFAM Transglycosylase-associated protein - - - 0.00000000000000000000000000005261 118.0
HFD2_k127_6503380_27 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000001858 96.0
HFD2_k127_6503380_28 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0000000000000000008226 89.0
HFD2_k127_6503380_29 - - - - 0.000000000000000007134 94.0
HFD2_k127_6503380_3 FtsX-like permease family K02004 - - 1.129e-224 724.0
HFD2_k127_6503380_30 Cytotoxic translational repressor of toxin-antitoxin stability system K06218 - - 0.000002018 52.0
HFD2_k127_6503380_31 transcriptional regulator - - - 0.000004038 52.0
HFD2_k127_6503380_32 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.00008575 52.0
HFD2_k127_6503380_4 transport system involved in gliding motility, auxiliary component K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006913 560.0
HFD2_k127_6503380_5 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 519.0
HFD2_k127_6503380_6 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 473.0
HFD2_k127_6503380_7 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005645 435.0
HFD2_k127_6503380_8 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 398.0
HFD2_k127_6503380_9 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003326 391.0
HFD2_k127_652135_0 Sodium proton antiporter, NhaD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009717 411.0
HFD2_k127_652135_1 - - - - 0.00000000000000000007646 100.0
HFD2_k127_652135_2 PFAM Integrase catalytic - - - 0.00000000002951 63.0
HFD2_k127_6554392_0 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004435 537.0
HFD2_k127_6554392_1 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 472.0
HFD2_k127_6554392_10 - - - - 0.00000000000000001916 97.0
HFD2_k127_6554392_2 TIGRFAM cytochrome C family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 414.0
HFD2_k127_6554392_3 glycosyl transferase family 8 - - - 0.0000000000000000000000000000000000000000000000000002998 198.0
HFD2_k127_6554392_4 glycosyltransferase - - - 0.000000000000000000000000000000000000000000000002057 188.0
HFD2_k127_6554392_5 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000004722 179.0
HFD2_k127_6554392_7 Acid phosphatase homologues - - - 0.0000000000000000000000000000000000011 145.0
HFD2_k127_6554392_8 Aspartyl protease - - - 0.0000000000000000000000000008583 124.0
HFD2_k127_6554392_9 Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC - - - 0.000000000000000000000004126 117.0
HFD2_k127_6575524_0 protease with the C-terminal PDZ domain - - - 4.555e-268 841.0
HFD2_k127_6575524_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 413.0
HFD2_k127_6575524_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 404.0
HFD2_k127_6575524_3 [2Fe-2S] binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000004009 217.0
HFD2_k127_6576057_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000681 594.0
HFD2_k127_6576057_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.000000000000000000000000000000000000000000000000000000000000002809 221.0
HFD2_k127_6583199_0 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004554 491.0
HFD2_k127_6583199_1 COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases K00101,K15054 - 1.1.2.3,1.1.99.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 398.0
HFD2_k127_6596683_0 Oligopeptidase F K08602 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006809 528.0
HFD2_k127_6596683_1 Membrane K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00000000000000000000000000000000000000002412 161.0
HFD2_k127_6596683_2 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000487 152.0
HFD2_k127_6596683_3 - - - - 0.000000000000000003622 97.0
HFD2_k127_6647589_0 COG1629 Outer membrane receptor proteins, mostly Fe transport K16090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001363 253.0
HFD2_k127_6647589_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000003872 105.0
HFD2_k127_6647589_2 PFAM FecR protein K07165 - - 0.0000413 53.0
HFD2_k127_666663_0 Dehydrogenase K17760 - 1.1.9.1 2.539e-232 736.0
HFD2_k127_666663_1 Aldehyde dehydrogenase family K00151 - 1.2.1.60 1.663e-214 675.0
HFD2_k127_666663_10 Ankyrin repeat domain 44 K15502,K15503 - - 0.00000000002792 73.0
HFD2_k127_666663_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 429.0
HFD2_k127_666663_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K13039 - 4.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000008277 258.0
HFD2_k127_666663_4 Sulfopyruvate decarboxylase subunit alpha K06034 - 4.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000002961 227.0
HFD2_k127_666663_5 antibiotic catabolic process K13277,K20276 - - 0.0000000000000000000000000000000000005344 158.0
HFD2_k127_666663_6 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K13075 - 3.1.1.81 0.000000000000000000000000000000001664 134.0
HFD2_k127_666663_7 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000001155 92.0
HFD2_k127_666663_8 PQQ enzyme repeat K17760 - 1.1.9.1 0.00000000000000001817 90.0
HFD2_k127_666663_9 - - - - 0.000000000001075 76.0
HFD2_k127_6716214_0 Putative diguanylate phosphodiesterase K13245 - 3.1.4.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 413.0
HFD2_k127_6716214_1 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.00000000000000000000000000000000000000000000000000000000000000000000000006388 253.0
HFD2_k127_6716214_2 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000000000000000000000000000000000000002178 237.0
HFD2_k127_6716214_3 Redoxin K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000002545 200.0
HFD2_k127_6716214_4 Alpha/beta hydrolase of unknown function (DUF900) - - - 0.0000000000000000000000000002347 129.0
HFD2_k127_6716214_5 Ceramidase - - - 0.000000000000196 79.0
HFD2_k127_6756094_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 570.0
HFD2_k127_6756094_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000005775 209.0
HFD2_k127_6756094_2 Domain of unknown function (DUF1330) - - - 0.00000000000000000000000000000004806 127.0
HFD2_k127_6811598_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 5.69e-203 639.0
HFD2_k127_6811598_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 490.0
HFD2_k127_6811598_2 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 376.0
HFD2_k127_6811598_3 thiolester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 357.0
HFD2_k127_6811598_4 - - - - 0.000000000000000000000000000000001958 131.0
HFD2_k127_6811598_5 - - - - 0.000000000000000000000000005368 121.0
HFD2_k127_6811598_6 - - - - 0.0000000000000000001398 99.0
HFD2_k127_6811598_7 - - - - 0.0000000000000000008229 98.0
HFD2_k127_6811598_8 Structurally related to pyridoxine 5''-phosphate oxidase K07006 - - 0.0000000000000003546 79.0
HFD2_k127_6811598_9 Cupin - - - 0.000000008146 65.0
HFD2_k127_6837776_0 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 3.881e-218 704.0
HFD2_k127_6837776_1 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003312 622.0
HFD2_k127_6837776_10 Glycosyl transferase family 41 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 297.0
HFD2_k127_6837776_11 transduction histidine kinase K07716 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002604 299.0
HFD2_k127_6837776_12 Aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000007115 240.0
HFD2_k127_6837776_13 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000001315 233.0
HFD2_k127_6837776_14 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000139 230.0
HFD2_k127_6837776_15 Putative transmembrane protein (Alph_Pro_TM) - - - 0.0000000000000000000000000000000000000000000000000000008832 201.0
HFD2_k127_6837776_16 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000001072 196.0
HFD2_k127_6837776_17 Putative peptidoglycan binding domain K07126,K13582 - - 0.00000000000000000000000000000000000000004762 173.0
HFD2_k127_6837776_18 Protein of unknown function (DUF962) - - - 0.000000000000000000000000000000005294 139.0
HFD2_k127_6837776_19 LUD domain K00782 - - 0.00000000000000000000000005101 121.0
HFD2_k127_6837776_2 Acyl-CoA dehydrogenase, N-terminal domain K00252 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.3.8.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008657 595.0
HFD2_k127_6837776_20 Cysteine-rich secretory protein family - - - 0.00000000000004522 79.0
HFD2_k127_6837776_3 Glycosyl transferase family 41 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004887 584.0
HFD2_k127_6837776_4 LUD domain K18929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007125 523.0
HFD2_k127_6837776_5 FIST C domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006399 407.0
HFD2_k127_6837776_6 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 376.0
HFD2_k127_6837776_7 Cysteine-rich domain K18928 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007395 323.0
HFD2_k127_6837776_8 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008369 329.0
HFD2_k127_6837776_9 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003586 303.0
HFD2_k127_684992_0 Squalene-hopene cyclase C-terminal domain K06045 - 4.2.1.129,5.4.99.17 6.332e-306 948.0
HFD2_k127_684992_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 3.124e-303 940.0
HFD2_k127_684992_10 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007166 547.0
HFD2_k127_684992_11 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008104 512.0
HFD2_k127_684992_12 short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 500.0
HFD2_k127_684992_13 of poly-gamma-glutamate biosynthesis (Capsule formation) K07282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005266 503.0
HFD2_k127_684992_14 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006564 507.0
HFD2_k127_684992_15 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 462.0
HFD2_k127_684992_16 Flavin containing amine oxidoreductase K21677 - 1.17.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006738 461.0
HFD2_k127_684992_17 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004462 448.0
HFD2_k127_684992_18 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 431.0
HFD2_k127_684992_19 UbiA prenyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 388.0
HFD2_k127_684992_2 ATPases associated with a variety of cellular activities K02003,K05685 - - 5.022e-290 905.0
HFD2_k127_684992_20 Phytoene synthase K21678 - 2.5.1.103 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005143 334.0
HFD2_k127_684992_21 Reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 325.0
HFD2_k127_684992_22 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009975,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:1901360 6.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004564 320.0
HFD2_k127_684992_23 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007414 317.0
HFD2_k127_684992_24 PFAM Endonuclease Exonuclease phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 305.0
HFD2_k127_684992_25 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 294.0
HFD2_k127_684992_26 Dienelactone hydrolase family K07100 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001116 284.0
HFD2_k127_684992_27 Acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008806 278.0
HFD2_k127_684992_28 Phosphoribosyl transferase domain K07100 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001271 266.0
HFD2_k127_684992_29 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000046 256.0
HFD2_k127_684992_3 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 4.579e-252 792.0
HFD2_k127_684992_30 Protein of unknown function (DUF3775) - - - 0.0000000000000000000000000000000000000000000000000000000000001351 215.0
HFD2_k127_684992_31 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000000000000001663 203.0
HFD2_k127_684992_32 BON domain - - - 0.0000000000000000000000000000000000000000000000000004014 193.0
HFD2_k127_684992_33 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000000006256 178.0
HFD2_k127_684992_34 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000001066 178.0
HFD2_k127_684992_35 Lysylphosphatidylglycerol synthase TM region - - - 0.00000000000000000000000000000000000000000000002983 184.0
HFD2_k127_684992_36 Uncharacterized conserved protein (DUF2267) - - - 0.000000000000000000000000000000000000000000005916 166.0
HFD2_k127_684992_37 GYD domain - - - 0.000000000000000000000000000000000000000000006974 167.0
HFD2_k127_684992_38 GtrA-like protein - - - 0.00000000000000000000000000000000000000001987 156.0
HFD2_k127_684992_39 Uncharacterized conserved protein (DUF2267) - - - 0.0000000000000000000000000000000000000000429 157.0
HFD2_k127_684992_4 MMPL family K07003 - - 1.821e-236 758.0
HFD2_k127_684992_40 Phosphorylase superfamily K01243 - 3.2.2.9 0.0000000000000000000000000000000000000001367 158.0
HFD2_k127_684992_41 THUMP - - - 0.000000000000000000000000000000000000001184 158.0
HFD2_k127_684992_42 PFAM toluene tolerance family protein K07323 - - 0.000000000000000000000000000000000000001497 154.0
HFD2_k127_684992_43 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.0000000000000000000000000000000000003584 145.0
HFD2_k127_684992_44 CDP-archaeol synthase K19664 - 2.7.7.67 0.0000000000000000000000000000000000004579 145.0
HFD2_k127_684992_45 - - - - 0.00000000000000000000009957 105.0
HFD2_k127_684992_46 ChaB K06197 - - 0.000000000001102 68.0
HFD2_k127_684992_48 - - - - 0.000000002064 64.0
HFD2_k127_684992_49 - - - - 0.0000008019 51.0
HFD2_k127_684992_5 B12 binding domain - - - 1.584e-231 727.0
HFD2_k127_684992_50 mRNA binding K07339 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.00005963 48.0
HFD2_k127_684992_6 Domain of unknown function (DUF3463) - - - 5.944e-207 649.0
HFD2_k127_684992_7 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K05939 - 2.3.1.40,6.2.1.20 2.251e-198 632.0
HFD2_k127_684992_8 PFAM Radical SAM K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007458 582.0
HFD2_k127_684992_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 581.0
HFD2_k127_6860924_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005806 259.0
HFD2_k127_6860924_1 helix_turn_helix, Lux Regulon K07684 - - 0.00000000000000000000000000000000000000000000000000000000000007209 220.0
HFD2_k127_6893238_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002008 272.0
HFD2_k127_6893238_1 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000000000000000000832 192.0
HFD2_k127_6893238_2 RDD family - - - 0.000000000002516 78.0
HFD2_k127_6894606_0 FtsX-like permease family K05685 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0008144,GO:0008150,GO:0008559,GO:0015238,GO:0015399,GO:0015405,GO:0015893,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042802,GO:0042891,GO:0042895,GO:0042908,GO:0042910,GO:0043167,GO:0043168,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046618,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:1901265,GO:1901363,GO:1902495,GO:1990195,GO:1990196,GO:1990351 - 5.427e-244 773.0
HFD2_k127_6894606_1 DNA ligase K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007993 531.0
HFD2_k127_6894606_10 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001183 286.0
HFD2_k127_6894606_11 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006764 272.0
HFD2_k127_6894606_12 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000001237 228.0
HFD2_k127_6894606_13 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000009879 203.0
HFD2_k127_6894606_14 acyl-CoA dehydrogenase K06445 - - 0.0000000000000000000000000000000000000000000000000009397 190.0
HFD2_k127_6894606_15 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000006574 171.0
HFD2_k127_6894606_16 Bacterial extracellular solute-binding protein - - - 0.000000000000000000000000000000000000000000629 171.0
HFD2_k127_6894606_17 Bacterial extracellular solute-binding protein K02020,K22003 - 5.3.3.7 0.000000000000000000000000000000000000000006538 166.0
HFD2_k127_6894606_18 ClpX C4-type zinc finger - - - 0.0000000000000000000000000000000000579 137.0
HFD2_k127_6894606_19 Bacterial extracellular solute-binding protein K02020 - - 0.000000000000000000000000000000001311 139.0
HFD2_k127_6894606_2 ABC-type sulfate transport system, periplasmic component K02048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004095 440.0
HFD2_k127_6894606_20 - - - - 0.000000000000000000001734 105.0
HFD2_k127_6894606_21 Protein of unknown function (DUF3309) - - - 0.00000000000000001537 89.0
HFD2_k127_6894606_22 Protein of unknown function (DUF1328) - - - 0.00000000000000009444 81.0
HFD2_k127_6894606_23 Bacterial extracellular solute-binding protein - - - 0.00000000000002068 82.0
HFD2_k127_6894606_24 lipid kinase activity - - - 0.00000000000009626 83.0
HFD2_k127_6894606_25 Bacterial extracellular solute-binding protein K02020,K22003 - 5.3.3.7 0.0000000003047 66.0
HFD2_k127_6894606_26 - - - - 0.000002657 52.0
HFD2_k127_6894606_3 sulfate transport system, permease K02047 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008624 397.0
HFD2_k127_6894606_4 sulfate transport system, permease K02046 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 369.0
HFD2_k127_6894606_5 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 363.0
HFD2_k127_6894606_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 355.0
HFD2_k127_6894606_7 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 317.0
HFD2_k127_6894606_8 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 317.0
HFD2_k127_6894606_9 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 328.0
HFD2_k127_6929727_0 Formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.0 1583.0
HFD2_k127_6929727_1 Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 1.534e-282 882.0
HFD2_k127_6929727_2 Respiratory-chain NADH dehydrogenase 51 Kd subunit K00122,K00124,K00335 - 1.17.1.9,1.6.5.3 7.816e-241 756.0
HFD2_k127_6929727_3 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000003405 261.0
HFD2_k127_6929727_4 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000000001827 242.0
HFD2_k127_6929727_5 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000000000000000000000005267 205.0
HFD2_k127_6929727_6 Thioredoxin-like [2Fe-2S] ferredoxin K00127 - - 0.00000000000000000000000000000000000000000000000000001535 193.0
HFD2_k127_6929727_7 excinuclease ABC activity - - - 0.00000000000000000000000000000000000001344 152.0
HFD2_k127_6929727_8 Protein of unknown function (DUF559) - - - 0.00000000000000000000000006704 110.0
HFD2_k127_6929727_9 formate dehydrogenase K00126 - 1.17.1.9 0.00000000000000001425 89.0
HFD2_k127_6935147_0 Protein of unknown function (DUF1116) K02381 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 420.0
HFD2_k127_6935147_1 membrane K07335 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005784 276.0
HFD2_k127_6935147_2 Succinyl-CoA synthetase, alpha subunit K02381 - - 0.000000000000000000000000000000000000000000671 163.0
HFD2_k127_7012273_0 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 509.0
HFD2_k127_7012273_1 ATPase family associated with various cellular activities (AAA) K03924 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000486 447.0
HFD2_k127_7012273_2 Poly A polymerase head domain K00970 - 2.7.7.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 391.0
HFD2_k127_7012273_3 Trypsin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 359.0
HFD2_k127_7012273_4 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006079 294.0
HFD2_k127_7012273_5 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.00000000000000000000000000000000000000000004717 169.0
HFD2_k127_7012273_6 Protein phosphatase 2C - - - 0.0000000000000000000000000000000000000000001183 170.0
HFD2_k127_7012273_7 Aerotolerance regulator N-terminal - - - 0.00000000000000000000000000000001876 128.0
HFD2_k127_7012273_8 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.000000000000000746 85.0
HFD2_k127_7012273_9 - - - - 0.00000000001609 71.0
HFD2_k127_7014658_0 asparaginyl-tRNA synthetase K01893 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 2.736e-225 709.0
HFD2_k127_7014658_1 B12 binding domain - - - 1.607e-212 678.0
HFD2_k127_7014658_10 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 465.0
HFD2_k127_7014658_11 transport, permease protein K01992 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 407.0
HFD2_k127_7014658_12 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000062 417.0
HFD2_k127_7014658_13 Exopolysaccharide biosynthesis protein YbjH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 411.0
HFD2_k127_7014658_14 SPFH domain / Band 7 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 377.0
HFD2_k127_7014658_15 Amidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008393 376.0
HFD2_k127_7014658_16 PFAM secretion protein HlyD family protein K03543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004908 347.0
HFD2_k127_7014658_17 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 319.0
HFD2_k127_7014658_18 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006144 324.0
HFD2_k127_7014658_19 esterase K01432 - 3.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004756 313.0
HFD2_k127_7014658_2 ornithine cyclodeaminase K01750 - 4.3.1.12 7.028e-201 630.0
HFD2_k127_7014658_20 Transposase K07481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 301.0
HFD2_k127_7014658_21 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 295.0
HFD2_k127_7014658_22 Protein of unknown function (DUF1348) K09958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005499 275.0
HFD2_k127_7014658_23 Pfam Glycosyl transferase family 2 K13683 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003261 268.0
HFD2_k127_7014658_24 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000001119 241.0
HFD2_k127_7014658_25 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000001031 242.0
HFD2_k127_7014658_26 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001608 236.0
HFD2_k127_7014658_27 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.000000000000000000000000000000000000000000000000000000000000006892 226.0
HFD2_k127_7014658_28 Methyltransferase K08316 - 2.1.1.171 0.000000000000000000000000000000000000000000000000000000000003722 213.0
HFD2_k127_7014658_29 PepSY-associated TM region - - - 0.00000000000000000000000000000000000000000000000000000000006278 219.0
HFD2_k127_7014658_3 glucose import - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 616.0
HFD2_k127_7014658_30 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - - 0.00000000000000000000000000000000000000000000002649 177.0
HFD2_k127_7014658_31 AefR-like transcriptional repressor, C-terminal region K18301 - - 0.000000000000000000000000000000000000448 148.0
HFD2_k127_7014658_32 Ornithine cyclodeaminase K01750 - 4.3.1.12 0.0000000000000000000000000000000001095 154.0
HFD2_k127_7014658_33 Amidohydrolase family - - - 0.0000000000000000000000000000000002406 151.0
HFD2_k127_7014658_34 3-demethylubiquinone-9 3-methyltransferase - - - 0.0000000000000000000000000000000003387 134.0
HFD2_k127_7014658_35 Methyltransferase domain - - - 0.00000000000000000000000000000982 134.0
HFD2_k127_7014658_36 Protein of unknown function (DUF559) - - - 0.00000000000000000000000000001167 127.0
HFD2_k127_7014658_37 Secretion protein, HlyD K03543 - - 0.000000000000000000000000002417 115.0
HFD2_k127_7014658_38 - - - - 0.0000000000000000000000006282 111.0
HFD2_k127_7014658_39 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase - - - 0.000000000000000000000006598 115.0
HFD2_k127_7014658_4 PFAM Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000065 605.0
HFD2_k127_7014658_40 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000001315 108.0
HFD2_k127_7014658_41 PFAM Oxidoreductase, molybdopterin binding - - - 0.000000000000000001769 95.0
HFD2_k127_7014658_42 Immunity protein 27 - - - 0.000000000000006021 82.0
HFD2_k127_7014658_43 Group 4 capsule polysaccharide lipoprotein gfcB, YjbF - - - 0.000000000000038 81.0
HFD2_k127_7014658_44 - - - - 0.000000000000959 77.0
HFD2_k127_7014658_45 PAS domain - - - 0.000000000001102 76.0
HFD2_k127_7014658_46 Protein of unknown function (DUF3096) - - - 0.00000000007725 64.0
HFD2_k127_7014658_47 Polysaccharide biosynthesis protein K03328,K16695 - - 0.00003355 56.0
HFD2_k127_7014658_5 M28 family peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008744 584.0
HFD2_k127_7014658_6 Disulphide bond corrector protein DsbC K04084 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004453 556.0
HFD2_k127_7014658_7 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 501.0
HFD2_k127_7014658_8 ABC transporter K01990 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 490.0
HFD2_k127_7014658_9 Polysaccharide biosynthesis protein K08679 - 5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 491.0
HFD2_k127_7027004_0 protein conserved in bacteria K09987 - - 0.000000000000000000000000000000000000000000000000000000000000000000001007 246.0
HFD2_k127_7027004_1 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000000006922 68.0
HFD2_k127_7044665_0 histidine kinase A domain protein - - - 0.0000000000000000000000000000526 127.0
HFD2_k127_7044665_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.000000000000000000000008686 113.0
HFD2_k127_7049967_0 Putative sugar-binding N-terminal domain K21948 - 2.7.1.217 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008391 503.0
HFD2_k127_7049967_1 type I restriction modification DNA specificity domain K03427 - 2.1.1.72 0.0000000000000000000000000000000000000000000003444 172.0
HFD2_k127_7049967_2 Class II Aldolase and Adducin N-terminal domain K22130 - 4.1.1.104 0.000000000000000000000000001068 113.0
HFD2_k127_7049967_3 InterPro IPR007367 - - - 0.000000000000000000000433 98.0
HFD2_k127_7055832_0 Transferrin receptor-like dimerisation domain - - - 1.041e-281 893.0
HFD2_k127_7055832_1 MmgE/PrpD family - - - 6.897e-212 678.0
HFD2_k127_7055832_10 methionine sulfoxide reductase K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000002414 228.0
HFD2_k127_7055832_11 Tripartite tricarboxylate transporter TctB family - - - 0.0000000000000000000000002672 111.0
HFD2_k127_7055832_12 GYD domain - - - 0.0000000000000000000007263 103.0
HFD2_k127_7055832_13 C-lobe and N-lobe beta barrels of Tf-binding protein B - - - 0.000000000000000004224 96.0
HFD2_k127_7055832_2 Protein conserved in bacteria - - - 2.474e-207 655.0
HFD2_k127_7055832_3 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003458 619.0
HFD2_k127_7055832_4 Tripartite tricarboxylate transporter TctA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 533.0
HFD2_k127_7055832_5 FAD binding domain K00480,K22270 - 1.14.13.1,1.14.13.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 460.0
HFD2_k127_7055832_6 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009742 400.0
HFD2_k127_7055832_7 Belongs to the ABC transporter superfamily K02031,K12371,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 363.0
HFD2_k127_7055832_8 Protein of unknown function (DUF560) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 317.0
HFD2_k127_7055832_9 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003003 284.0
HFD2_k127_7086266_0 Catalyzes the synthesis of activated sulfate K00955 - 2.7.1.25,2.7.7.4 1.642e-299 932.0
HFD2_k127_7086266_1 Sulfotransferase family - - - 1.958e-211 679.0
HFD2_k127_7086266_10 - - - - 0.00000000000000002021 92.0
HFD2_k127_7086266_11 protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis - - - 0.000000000000008592 82.0
HFD2_k127_7086266_12 Invasion associated locus B (IalB) protein - - - 0.0000000005705 68.0
HFD2_k127_7086266_13 Invasion associated locus B (IalB) protein - - - 0.000001948 58.0
HFD2_k127_7086266_2 Type I secretion system ATPase K12541 - - 1.125e-196 636.0
HFD2_k127_7086266_3 COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase and related enzymes K00957 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 527.0
HFD2_k127_7086266_4 HlyD membrane-fusion protein of T1SS K02022,K12542 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005125 439.0
HFD2_k127_7086266_5 TIGRFAM type I secretion outer membrane protein, TolC family K12543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007384 392.0
HFD2_k127_7086266_6 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000001316 269.0
HFD2_k127_7086266_7 calcium- and calmodulin-responsive adenylate cyclase activity K01317 - 3.4.21.10 0.00000000000000000000000000000000000000000000000000004002 214.0
HFD2_k127_7086266_8 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000002749 167.0
HFD2_k127_7086266_9 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.000000000000000000000000000000001361 151.0
HFD2_k127_713790_0 Binding-protein-dependent transport system inner membrane component K02029 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009805 314.0
HFD2_k127_713790_1 Bacterial periplasmic substrate-binding proteins K02030 - - 0.0000000000000000000000000000000000000003674 162.0
HFD2_k127_7141388_0 Belongs to the CinA family K03742 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005493 535.0
HFD2_k127_7141388_1 pyrroloquinoline quinone binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008609 507.0
HFD2_k127_7141388_2 2'-5' RNA ligase superfamily K01975 - 3.1.4.58 0.00000000000000000000000000000000000000000000000000000002091 202.0
HFD2_k127_7141388_3 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000001986 164.0
HFD2_k127_7145082_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 1.983e-305 955.0
HFD2_k127_7145082_1 Peptidase S46 - - - 9.548e-300 933.0
HFD2_k127_7145082_10 ligase activity - - - 0.0000000000000000000000000000000000000000000000000000000000006136 225.0
HFD2_k127_7145082_11 Galactose oxidase, central domain - - - 0.0000000000000000000000000000000000000000000000000000000000009518 222.0
HFD2_k127_7145082_12 von Willebrand factor, type A - - - 0.00000000000000000000000000000000000000000000000001462 192.0
HFD2_k127_7145082_13 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000000000000000000000000000002022 179.0
HFD2_k127_7145082_14 Uncharacterized conserved protein (DUF2267) - - - 0.000000000000000000000000000000000000000000000001764 177.0
HFD2_k127_7145082_15 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.000000000000000000000000000000000000000000000003497 186.0
HFD2_k127_7145082_16 Alkylhydroperoxidase AhpD family core domain-containing protein 7 - - - 0.00000000000000000000000000000000000000001186 159.0
HFD2_k127_7145082_17 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000002658 163.0
HFD2_k127_7145082_18 D-isomer specific 2-hydroxyacid dehydrogenase K00015,K00058 - 1.1.1.26,1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000001943 155.0
HFD2_k127_7145082_2 Belongs to the peptidase M16 family K07263 - - 4.065e-246 790.0
HFD2_k127_7145082_20 Plasmid maintenance system killer K07334 - - 0.0000000000000000001292 91.0
HFD2_k127_7145082_21 addiction module antidote protein HigA - - - 0.000000000000005557 78.0
HFD2_k127_7145082_23 cellulase activity - - - 0.00000000001462 80.0
HFD2_k127_7145082_24 addiction module antidote protein HigA - - - 0.00000000006606 64.0
HFD2_k127_7145082_25 Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM) K15256 GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281 - 0.00000505 58.0
HFD2_k127_7145082_27 PFAM Plasmid maintenance system killer K07334 - - 0.0002559 46.0
HFD2_k127_7145082_3 Phosphoribosyl transferase domain K07100 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 525.0
HFD2_k127_7145082_4 Major Facilitator Superfamily K08223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 486.0
HFD2_k127_7145082_5 Belongs to the UbiD family K03182 - 4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 445.0
HFD2_k127_7145082_6 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005523 417.0
HFD2_k127_7145082_7 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 397.0
HFD2_k127_7145082_8 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 309.0
HFD2_k127_7145082_9 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 312.0
HFD2_k127_7147966_0 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 405.0
HFD2_k127_7147966_1 Adenylate cyclase - - - 0.00006585 52.0
HFD2_k127_7151590_0 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K00666 - - 8.871e-236 739.0
HFD2_k127_7151590_1 AMP-binding enzyme C-terminal domain K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009067 430.0
HFD2_k127_7151590_2 - - - - 0.00000000000000000000125 106.0
HFD2_k127_7153543_0 ATPase with chaperone activity K07391 - - 9.37e-222 697.0
HFD2_k127_7153543_1 SMART Tetratricopeptide domain protein - - - 9.459e-222 715.0
HFD2_k127_7153543_10 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000002739 202.0
HFD2_k127_7153543_11 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000008084 177.0
HFD2_k127_7153543_12 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000007449 171.0
HFD2_k127_7153543_13 polysaccharide biosynthetic process K03379 - 1.14.13.22 0.0000000000000000000000000000000000001163 158.0
HFD2_k127_7153543_14 Low affinity iron permease - - - 0.00000000000000000000000000000007831 134.0
HFD2_k127_7153543_15 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000000000000000000000000000000197 126.0
HFD2_k127_7153543_16 periplasmic or secreted lipoprotein - - - 0.00000000000000000000000000001299 126.0
HFD2_k127_7153543_17 - - - - 0.0000000000000000000000003607 112.0
HFD2_k127_7153543_18 Belongs to the UPF0102 family K07460 - - 0.000000000000000000000001189 109.0
HFD2_k127_7153543_2 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 468.0
HFD2_k127_7153543_3 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007241 413.0
HFD2_k127_7153543_4 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 414.0
HFD2_k127_7153543_5 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 339.0
HFD2_k127_7153543_6 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003898 316.0
HFD2_k127_7153543_7 LppC putative lipoprotein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009403 294.0
HFD2_k127_7153543_8 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000004944 248.0
HFD2_k127_7153543_9 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001416 248.0
HFD2_k127_7153549_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 304.0
HFD2_k127_7153549_1 TonB dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000295 247.0
HFD2_k127_7153549_2 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000001276 232.0
HFD2_k127_7153549_3 integral membrane protein - - - 0.0000000000000000000000000000000000000000000000000000005555 197.0
HFD2_k127_7153549_4 - - - - 0.0000000000000000004862 98.0
HFD2_k127_7153549_5 Adenylate cyclase - - - 0.000000000000000001576 98.0
HFD2_k127_7153549_6 resistance protein K14166 - - 0.0000000000000008178 91.0
HFD2_k127_7153549_7 cAMP biosynthetic process - - - 0.0000000001828 65.0
HFD2_k127_7157998_0 PEP-utilising enzyme, N-terminal K08484 - 2.7.3.9 2.442e-251 797.0
HFD2_k127_7157998_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005005 578.0
HFD2_k127_7157998_10 protein conserved in bacteria K15539 - - 0.0000000000000000000000000000000000003752 153.0
HFD2_k127_7157998_11 Protein of unknown function (DUF1178) - - - 0.000000000000000000000000000000000001761 142.0
HFD2_k127_7157998_12 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.00000000000000000000000000000006825 126.0
HFD2_k127_7157998_13 protein conserved in bacteria K09991 - - 0.00000000000001092 83.0
HFD2_k127_7157998_2 ACT domain K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 580.0
HFD2_k127_7157998_3 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 460.0
HFD2_k127_7157998_4 Carbon-nitrogen hydrolase K11206 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 346.0
HFD2_k127_7157998_5 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003139 329.0
HFD2_k127_7157998_6 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 294.0
HFD2_k127_7157998_7 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003424 266.0
HFD2_k127_7157998_8 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000508 253.0
HFD2_k127_7157998_9 Ribosomal RNA adenine dimethylase K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000006782 209.0
HFD2_k127_7159884_0 PFAM ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 385.0
HFD2_k127_7159884_1 Periplasmic binding protein K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 327.0
HFD2_k127_7226162_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 7.271e-237 744.0
HFD2_k127_7226162_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 1.413e-217 681.0
HFD2_k127_7226162_2 SseB protein C-terminal domain - - - 0.00000000000000000000000000000000001469 145.0
HFD2_k127_7226162_3 - - - - 0.0000003299 59.0
HFD2_k127_7352500_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 9.47e-321 989.0
HFD2_k127_7352500_1 B3/4 domain K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 1.114e-297 934.0
HFD2_k127_7352500_10 N-terminal domain of oxidoreductase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 390.0
HFD2_k127_7352500_11 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 368.0
HFD2_k127_7352500_12 Chromosome Partitioning K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 358.0
HFD2_k127_7352500_13 membrane-bound lytic murein transglycosylase K08304 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 357.0
HFD2_k127_7352500_14 COG0524 Sugar kinases, ribokinase family K00847 - 2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009181 341.0
HFD2_k127_7352500_15 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 329.0
HFD2_k127_7352500_16 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 324.0
HFD2_k127_7352500_17 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 318.0
HFD2_k127_7352500_18 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 319.0
HFD2_k127_7352500_19 dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 312.0
HFD2_k127_7352500_2 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 2.037e-269 843.0
HFD2_k127_7352500_20 Dihydrodipicolinate reductase, C-terminus K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000322 294.0
HFD2_k127_7352500_21 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 303.0
HFD2_k127_7352500_22 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 288.0
HFD2_k127_7352500_23 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003783 286.0
HFD2_k127_7352500_24 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000006175 262.0
HFD2_k127_7352500_25 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.000000000000000000000000000000000000000000000000000000000000000000001273 245.0
HFD2_k127_7352500_26 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000000000000000000000000000000000000000001139 238.0
HFD2_k127_7352500_27 membrane K08973 - - 0.0000000000000000000000000000000000000000000000000000222 192.0
HFD2_k127_7352500_28 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.0000000000000000000000000000000000000000000000000001393 193.0
HFD2_k127_7352500_29 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000004169 191.0
HFD2_k127_7352500_3 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.29e-235 734.0
HFD2_k127_7352500_30 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000003267 178.0
HFD2_k127_7352500_31 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000005533 183.0
HFD2_k127_7352500_32 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000002892 175.0
HFD2_k127_7352500_33 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.00000000000000000000000000000000000000000002571 166.0
HFD2_k127_7352500_34 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000008915 181.0
HFD2_k127_7352500_35 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0065003,GO:0070925,GO:0071826,GO:0071840 - 0.0000000000000000000000000000000000000000005542 163.0
HFD2_k127_7352500_36 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 GO:0002790,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.000000000000000000000000000000000000000008661 160.0
HFD2_k127_7352500_37 chromate transporter K07240 - - 0.00000000000000000000000000000000000002087 151.0
HFD2_k127_7352500_38 Integral membrane protein (DUF2244) - - - 0.0000000000000000000000000000001227 130.0
HFD2_k127_7352500_39 Smr domain - - - 0.000000000000000000000000000005503 124.0
HFD2_k127_7352500_4 COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 4.627e-230 732.0
HFD2_k127_7352500_40 - - - - 0.000000000000000000003545 98.0
HFD2_k127_7352500_41 Bacterial extracellular solute-binding protein K22003 - 5.3.3.7 0.000000000000000000008781 103.0
HFD2_k127_7352500_42 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000005004 92.0
HFD2_k127_7352500_43 TPR repeat - - - 0.0000000000000001367 87.0
HFD2_k127_7352500_44 Cation efflux family - - - 0.00000000000008173 79.0
HFD2_k127_7352500_45 - - - - 0.00000001428 62.0
HFD2_k127_7352500_46 - - - - 0.00001214 56.0
HFD2_k127_7352500_6 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 520.0
HFD2_k127_7352500_7 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 509.0
HFD2_k127_7352500_8 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004507 443.0
HFD2_k127_7352500_9 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006399 402.0
HFD2_k127_7355676_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 5.391e-269 836.0
HFD2_k127_7355676_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 1.928e-212 666.0
HFD2_k127_7355676_10 PFAM Preprotein translocase SecG subunit K03075 - - 0.0000000000000000000004346 102.0
HFD2_k127_7355676_11 Septum formation initiator - - - 0.00000000002453 68.0
HFD2_k127_7355676_2 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 505.0
HFD2_k127_7355676_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005224 482.0
HFD2_k127_7355676_4 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003247 426.0
HFD2_k127_7355676_5 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004842 337.0
HFD2_k127_7355676_6 Aldolase/RraA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001068 252.0
HFD2_k127_7355676_7 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000009227 231.0
HFD2_k127_7355676_8 MAPEG family K00799 - 2.5.1.18 0.00000000000000000000001446 105.0
HFD2_k127_7355676_9 cheY-homologous receiver domain - - - 0.00000000000000000000002565 109.0
HFD2_k127_7358989_0 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009945 478.0
HFD2_k127_7358989_1 - - - - 0.000000000000000000000000000000000006388 145.0
HFD2_k127_7439343_0 Peptidase M16C associated K06972 - - 1.826e-249 788.0
HFD2_k127_7482179_0 TonB dependent receptor K16090 - - 1.358e-228 733.0
HFD2_k127_7482179_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 6.544e-198 621.0
HFD2_k127_7482179_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 483.0
HFD2_k127_7482179_3 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000002309 220.0
HFD2_k127_7482179_4 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.000000000000000000000000000000000000000000883 160.0
HFD2_k127_7490391_0 COGs COG3127 ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component K02004 - - 0.000000000000000000000000007525 127.0
HFD2_k127_7501405_0 Methionine synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 462.0
HFD2_k127_7501405_1 Permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006943 413.0
HFD2_k127_7501405_2 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K05712,K10676 - 1.14.13.127,1.14.13.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000497 338.0
HFD2_k127_7501405_3 4,5-dihydroxyphthalate decarboxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006625 281.0
HFD2_k127_7501405_4 esterase lipase - - - 0.00000000000000000000000000000000000000000000000000000000000000009308 234.0
HFD2_k127_7501405_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000003587 149.0
HFD2_k127_7501405_6 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.000000000000000000000000000000009744 128.0
HFD2_k127_7501405_7 addiction module antidote protein, HigA family K21498 - - 0.0000000000000000000000000001321 120.0
HFD2_k127_7589474_0 COG0474 Cation transport ATPase K01537 - 3.6.3.8 0.0 1110.0
HFD2_k127_7589474_1 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.0 1025.0
HFD2_k127_7589474_10 DNA polymerase K02347 - - 6.231e-200 638.0
HFD2_k127_7589474_11 Dehydrogenase E1 component K11381,K21416 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 516.0
HFD2_k127_7589474_12 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009178 502.0
HFD2_k127_7589474_13 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 469.0
HFD2_k127_7589474_14 COG2230 Cyclopropane fatty acid synthase and related methyltransferases K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006698 449.0
HFD2_k127_7589474_15 dehydrogenase e1 component K00161,K00162 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006737 439.0
HFD2_k127_7589474_16 Belongs to the peptidase S1C family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007084 415.0
HFD2_k127_7589474_17 e3 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007239 393.0
HFD2_k127_7589474_18 COG1127 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 375.0
HFD2_k127_7589474_19 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 372.0
HFD2_k127_7589474_2 CoA binding domain K09181 - - 7.246e-315 987.0
HFD2_k127_7589474_20 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000386 355.0
HFD2_k127_7589474_21 Belongs to the peptidase S1C family K04771,K04772 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008364 355.0
HFD2_k127_7589474_22 Ornithine cyclodeaminase/mu-crystallin family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 352.0
HFD2_k127_7589474_23 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003351 351.0
HFD2_k127_7589474_24 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 334.0
HFD2_k127_7589474_25 16S rRNA methyltransferase RsmB/F K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 339.0
HFD2_k127_7589474_26 L,D-transpeptidase catalytic domain K21470 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000592 331.0
HFD2_k127_7589474_27 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 307.0
HFD2_k127_7589474_28 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009899 308.0
HFD2_k127_7589474_29 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004149 311.0
HFD2_k127_7589474_3 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895,K01907 - 6.2.1.1,6.2.1.16 4.591e-271 845.0
HFD2_k127_7589474_30 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009712 299.0
HFD2_k127_7589474_31 CBS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007922 266.0
HFD2_k127_7589474_32 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.000000000000000000000000000000000000000000000000000000000000000000000000007485 257.0
HFD2_k127_7589474_33 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001601 260.0
HFD2_k127_7589474_34 auxin efflux carrier family protein K07088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001182 258.0
HFD2_k127_7589474_35 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005961 252.0
HFD2_k127_7589474_36 beta-lactamase activity K07126 - - 0.00000000000000000000000000000000000000000000000000000000000000000002003 244.0
HFD2_k127_7589474_37 HpcH/HpaI aldolase/citrate lyase family K01630,K02510 - 4.1.2.20,4.1.2.52 0.0000000000000000000000000000000000000000000000000000000000000006154 230.0
HFD2_k127_7589474_38 PIN domain - - - 0.00000000000000000000000000000000000000000000000000000000003456 209.0
HFD2_k127_7589474_39 helix_turn_helix, cAMP Regulatory protein - - - 0.00000000000000000000000000000000000000000000000000002542 197.0
HFD2_k127_7589474_4 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 3.547e-260 816.0
HFD2_k127_7589474_40 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000000000005836 189.0
HFD2_k127_7589474_41 Protein of unknown function (DUF1194) - - - 0.00000000000000000000000000000000000000000000000002258 193.0
HFD2_k127_7589474_42 Aspartyl protease K06985 - - 0.0000000000000000000000000000000000000000002756 179.0
HFD2_k127_7589474_43 Universal stress protein - - - 0.0000000000000000000000000000000000000000006757 168.0
HFD2_k127_7589474_44 Protein required for attachment to host cells - - - 0.000000000000000000000000000000000000000007237 161.0
HFD2_k127_7589474_45 Signal transduction protein - - - 0.0000000000000000000000000000000000000002461 153.0
HFD2_k127_7589474_46 - - - - 0.000000000000000000000000000000000000002364 149.0
HFD2_k127_7589474_47 Universal stress protein - - - 0.0000000000000000000000000000000000001629 153.0
HFD2_k127_7589474_48 - - - - 0.0000000000000000000000000000000002251 135.0
HFD2_k127_7589474_49 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000003031 142.0
HFD2_k127_7589474_5 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 1.661e-258 803.0
HFD2_k127_7589474_50 CopG antitoxin of type II toxin-antitoxin system - - - 0.0000000000000000000000000000000003921 132.0
HFD2_k127_7589474_51 - - - - 0.0000000000000000000000000000007733 129.0
HFD2_k127_7589474_52 Phosphopantetheine attachment site - - - 0.000000000000000000000000001979 114.0
HFD2_k127_7589474_53 - - - - 0.000000000000000000000000003736 115.0
HFD2_k127_7589474_54 COG2826 Transposase and inactivated derivatives, IS30 family K07482 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004803,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006310,GO:0006313,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0030983,GO:0032135,GO:0032196,GO:0032991,GO:0032993,GO:0034641,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.000000000000000000000000005388 110.0
HFD2_k127_7589474_55 ChaB K06197 - - 0.000000000000000006258 87.0
HFD2_k127_7589474_56 - - - - 0.000000000000000007002 89.0
HFD2_k127_7589474_57 ChaB K06197 - - 0.0000000000008017 68.0
HFD2_k127_7589474_59 Leucine-rich repeat (LRR) protein - - - 0.000002332 52.0
HFD2_k127_7589474_6 Carbohydrate phosphorylase K00688 - 2.4.1.1 3.007e-250 784.0
HFD2_k127_7589474_60 PFAM Tetratricopeptide repeat - - - 0.00001341 53.0
HFD2_k127_7589474_61 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00006046 46.0
HFD2_k127_7589474_62 Transposase - - - 0.0001907 45.0
HFD2_k127_7589474_64 PIN domain - - - 0.0003157 46.0
HFD2_k127_7589474_7 MacB-like periplasmic core domain K02004 - - 1.574e-238 762.0
HFD2_k127_7589474_8 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088,K00364 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205,1.7.1.7 7.405e-227 713.0
HFD2_k127_7589474_9 all-trans-retinol 13,14-reductase activity - - - 3.466e-208 659.0
HFD2_k127_7595676_0 MmgE PrpD family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002013 277.0
HFD2_k127_7625630_0 Cupin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000401 351.0
HFD2_k127_7625630_1 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003673 292.0
HFD2_k127_7625630_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000006352 229.0
HFD2_k127_7625630_3 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase K16171 - 3.7.1.2 0.0000000000000000000000001438 107.0
HFD2_k127_7625630_4 Sodium:sulfate symporter transmembrane region - - - 0.0000000009142 63.0
HFD2_k127_7629905_0 DNA topological change - - - 3.281e-219 706.0
HFD2_k127_7629905_1 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 447.0
HFD2_k127_7629905_2 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001795 274.0
HFD2_k127_7629905_3 HWE histidine kinase - - - 0.00000000000000000000000000000000000000000000000000177 197.0
HFD2_k127_7629905_4 PFAM Ankyrin K06867 - - 0.000000000000000000000000004192 125.0
HFD2_k127_7629905_5 - - - - 0.000000000000000000002642 106.0
HFD2_k127_7629905_6 phosphorelay signal transduction system K02535 - 3.5.1.108 0.000000001068 64.0
HFD2_k127_7662713_0 beta-galactosidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 447.0
HFD2_k127_7662713_1 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000151 62.0
HFD2_k127_7662713_2 glyoxalase bleomycin resistance protein dioxygenase K01759 - 4.4.1.5 0.0000004108 57.0
HFD2_k127_7672850_0 - - - - 9.053e-250 785.0
HFD2_k127_7672850_1 ethanolamine utilization protein K04019 GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0030091,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009,GO:0071704,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009517 597.0
HFD2_k127_7672850_10 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000005079 225.0
HFD2_k127_7672850_11 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000006941 230.0
HFD2_k127_7672850_12 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins - - - 0.000000000000000000000000000000000000000000000000000001254 202.0
HFD2_k127_7672850_13 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000003597 170.0
HFD2_k127_7672850_14 Amidohydrolase family K01465 - 3.5.2.3 0.000000000000000000000000000000007182 137.0
HFD2_k127_7672850_15 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000005485 139.0
HFD2_k127_7672850_16 FtsX-like permease family K02004 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009405,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0051704,GO:0071944 - 0.000000000000000000001832 107.0
HFD2_k127_7672850_17 - - - - 0.0000000000000000008359 98.0
HFD2_k127_7672850_18 - - - - 0.000000000000009397 86.0
HFD2_k127_7672850_19 - - - - 0.00000000000005274 78.0
HFD2_k127_7672850_2 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 492.0
HFD2_k127_7672850_20 Protein of unknown function (DUF2933) - - - 0.000000005472 61.0
HFD2_k127_7672850_21 protein possibly involved in utilization of glycolate and propanediol - - - 0.0001903 51.0
HFD2_k127_7672850_3 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006009 388.0
HFD2_k127_7672850_4 Mitochondrial fission ELM1 K07276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 336.0
HFD2_k127_7672850_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003599 337.0
HFD2_k127_7672850_6 COGs COG1136 ABC-type antimicrobial peptide transport system ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008194 279.0
HFD2_k127_7672850_7 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000009531 266.0
HFD2_k127_7672850_8 Outer membrane lipoprotein-sorting protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004664 264.0
HFD2_k127_7672850_9 2OG-Fe(II) oxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005215 244.0
HFD2_k127_7680093_0 Domain of unknown function (DUF4339) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 376.0
HFD2_k127_7680093_1 COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005172 381.0
HFD2_k127_7680093_2 sequence-specific DNA binding - - - 0.00000000000000000000000000002764 122.0
HFD2_k127_7680093_3 acetyltransferase - - - 0.000000000000000000006683 96.0
HFD2_k127_7706204_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0031323,GO:0033238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0080090 2.7.7.42,2.7.7.89 2.025e-290 920.0
HFD2_k127_7706204_1 Nitrite and sulphite reductase 4Fe-4S domain K00381 - 1.8.1.2 8.451e-254 793.0
HFD2_k127_7706204_10 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003326 421.0
HFD2_k127_7706204_11 COG1629 Outer membrane receptor proteins, mostly Fe transport K16090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007532 406.0
HFD2_k127_7706204_12 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 412.0
HFD2_k127_7706204_13 Pfam:AmoA K07120 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008052 376.0
HFD2_k127_7706204_14 Putrescine transport system permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007806 366.0
HFD2_k127_7706204_15 Transcriptional regulatory protein, C terminal K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005198 362.0
HFD2_k127_7706204_16 Bacterial extracellular solute-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 350.0
HFD2_k127_7706204_17 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 344.0
HFD2_k127_7706204_18 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 315.0
HFD2_k127_7706204_19 pkhd-type hydroxylase K07336 GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0033554,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0098771 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 308.0
HFD2_k127_7706204_2 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 3.012e-227 714.0
HFD2_k127_7706204_20 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 313.0
HFD2_k127_7706204_21 Histidyl-tRNA synthetase K02502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000315 313.0
HFD2_k127_7706204_22 Belongs to the Orn Lys Arg decarboxylase class-II family K01581 - 4.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003012 309.0
HFD2_k127_7706204_23 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 299.0
HFD2_k127_7706204_24 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 287.0
HFD2_k127_7706204_25 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002201 298.0
HFD2_k127_7706204_26 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000001003 273.0
HFD2_k127_7706204_27 TIGRFAM YihY family protein (not ribonuclease BN) K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000003346 244.0
HFD2_k127_7706204_28 -acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000002764 216.0
HFD2_k127_7706204_29 - - - - 0.000000000000000000000000000000000000000000000000000000002244 218.0
HFD2_k127_7706204_3 COG1138 Cytochrome c biogenesis factor K02198 - - 1.147e-205 659.0
HFD2_k127_7706204_30 Transcriptional regulator, LysR family - - - 0.00000000000000000000000000000000000000000000000000000001902 210.0
HFD2_k127_7706204_31 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.000000000000000000000000000000000000000000000000004688 187.0
HFD2_k127_7706204_32 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000000000000000000000002288 174.0
HFD2_k127_7706204_33 Amidohydrolase family - - - 0.0000000000000000000000000000000000000006794 154.0
HFD2_k127_7706204_34 Bacterial protein of unknown function (DUF934) - - - 0.0000000000000000000000000000000000002288 147.0
HFD2_k127_7706204_35 - - - - 0.0000000000000000000000000000000003524 135.0
HFD2_k127_7706204_36 subunit of a heme lyase K02200 - - 0.00000000000000000000000000000001484 131.0
HFD2_k127_7706204_37 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000003544 128.0
HFD2_k127_7706204_38 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000001933 117.0
HFD2_k127_7706204_39 Protein conserved in bacteria - - - 0.00000000000000000000000001748 113.0
HFD2_k127_7706204_4 COG2366 Protein related to penicillin acylase K01434,K07116 - 3.5.1.11,3.5.1.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006922 561.0
HFD2_k127_7706204_40 Cytochrome c - - - 0.00000000000000000000001106 102.0
HFD2_k127_7706204_41 metal-dependent hydrolase with the TIM-barrel fold - - - 0.00000000000000000000002465 108.0
HFD2_k127_7706204_42 - - - - 0.000000000000000000001012 106.0
HFD2_k127_7706204_43 signal transduction histidine kinase K07716,K11357 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 0.000000000000000000005768 104.0
HFD2_k127_7706204_44 ABC-type multidrug transport system, ATPase component K01990 - - 0.0000000000000000002235 99.0
HFD2_k127_7706204_45 Cytochrome c - - - 0.000000000000000006975 87.0
HFD2_k127_7706204_46 Protein of unknown function (DUF2849) - - - 0.000000000000005081 79.0
HFD2_k127_7706204_47 ABC-type multidrug transport system, permease component K01992 - - 0.000000000000005751 85.0
HFD2_k127_7706204_48 peptidase - - - 0.000000535 60.0
HFD2_k127_7706204_5 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 539.0
HFD2_k127_7706204_6 TIGRFAM penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 531.0
HFD2_k127_7706204_7 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 440.0
HFD2_k127_7706204_8 NMT1/THI5 like K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 423.0
HFD2_k127_7706204_9 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000926 428.0
HFD2_k127_7734795_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K00087,K03520,K04108 - 1.17.1.4,1.2.5.3,1.3.7.9 2e-295 927.0
HFD2_k127_7734795_1 Dehydrogenase K00117 - 1.1.5.2 2.535e-257 811.0
HFD2_k127_7734795_10 Helix-turn-helix XRE-family like proteins K07726 - - 0.0000000000000003027 84.0
HFD2_k127_7734795_11 Protein of unknown function (FYDLN_acid) - - - 0.000000000000002753 82.0
HFD2_k127_7734795_2 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005172 613.0
HFD2_k127_7734795_3 lysine biosynthetic process via aminoadipic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004371 568.0
HFD2_k127_7734795_4 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 504.0
HFD2_k127_7734795_5 Belongs to the UPF0255 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 373.0
HFD2_k127_7734795_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000225 238.0
HFD2_k127_7734795_8 - - - - 0.0000000000000000000000002785 116.0
HFD2_k127_7734795_9 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.00000000000000000005235 92.0
HFD2_k127_774213_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 6.958e-304 937.0
HFD2_k127_774213_1 Putative modulator of DNA gyrase K03568 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 1.304e-226 711.0
HFD2_k127_774213_10 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000008801 60.0
HFD2_k127_774213_2 Threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 490.0
HFD2_k127_774213_3 Insulinase (Peptidase family M16) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 448.0
HFD2_k127_774213_4 cytochrome c oxidase subunit III K02276 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005742 393.0
HFD2_k127_774213_5 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008929 358.0
HFD2_k127_774213_6 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 325.0
HFD2_k127_774213_7 Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I K02258 GO:0008150,GO:0008535,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840 - 0.000000000000000000000000000000000000000000000000000000000002636 216.0
HFD2_k127_774213_8 PFAM Surfeit locus 1 family protein K14998 - - 0.0000000000000000000000000000000000000000000000008367 183.0
HFD2_k127_774213_9 Protein of unknown function (DUF983) - - - 0.0000000000000000000000000000000000003576 149.0
HFD2_k127_7742397_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 5.164e-302 942.0
HFD2_k127_7742397_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.267e-263 817.0
HFD2_k127_7742397_10 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 394.0
HFD2_k127_7742397_11 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004962 381.0
HFD2_k127_7742397_12 Heparinase II/III-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 396.0
HFD2_k127_7742397_13 7-keto-8-aminopelargonate synthetase and related enzymes K00652 - 2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 365.0
HFD2_k127_7742397_14 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007552 352.0
HFD2_k127_7742397_15 Serine acetyltransferase, N-terminal K00640 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009314,GO:0009333,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 352.0
HFD2_k127_7742397_16 Serine dehydrogenase proteinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 346.0
HFD2_k127_7742397_17 COG1702 Phosphate starvation-inducible protein PhoH K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008519 324.0
HFD2_k127_7742397_18 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 312.0
HFD2_k127_7742397_19 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006473 286.0
HFD2_k127_7742397_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.488e-256 798.0
HFD2_k127_7742397_20 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001605 277.0
HFD2_k127_7742397_21 PFAM alpha beta hydrolase fold K01561 - 3.8.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001787 269.0
HFD2_k127_7742397_22 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000002343 248.0
HFD2_k127_7742397_23 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935,K02169 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.197,6.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000003376 243.0
HFD2_k127_7742397_24 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004786 247.0
HFD2_k127_7742397_25 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000000000000000000004471 230.0
HFD2_k127_7742397_26 catechol 1,2-dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000112 215.0
HFD2_k127_7742397_27 tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000001905 229.0
HFD2_k127_7742397_28 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000003777 217.0
HFD2_k127_7742397_29 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000006802 210.0
HFD2_k127_7742397_3 bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 8.053e-219 690.0
HFD2_k127_7742397_30 Helix-turn-helix - - - 0.00000000000000000000000000000000000000000000000000000001325 204.0
HFD2_k127_7742397_31 Glutathione S-transferase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000004429 177.0
HFD2_k127_7742397_32 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000000000000000000002814 171.0
HFD2_k127_7742397_33 DoxX K15977 - - 0.0000000000000000000000000000000000000000001356 164.0
HFD2_k127_7742397_34 - - - - 0.000000000000000000000000000000000000006488 154.0
HFD2_k127_7742397_35 Produces ATP from ADP in the presence of a proton gradient across the membrane K02113,K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000008975 151.0
HFD2_k127_7742397_36 Succinate dehydrogenase Fumarate reductase K00241 - - 0.0000000000000000000000000000000002676 138.0
HFD2_k127_7742397_37 Bacterial SH3 domain K01876 - 6.1.1.12 0.0000000000000000000000000000000003015 138.0
HFD2_k127_7742397_38 GGDEF domain - - - 0.0000000000000000000000000000000004757 147.0
HFD2_k127_7742397_39 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000001038 143.0
HFD2_k127_7742397_4 Aminotransferase class-III K00822,K00833 - 2.6.1.18,2.6.1.62 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 518.0
HFD2_k127_7742397_40 response to cobalt ion - GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0010045,GO:0010243,GO:0030288,GO:0030313,GO:0031975,GO:0032025,GO:0033554,GO:0042221,GO:0042597,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:1901652,GO:1901698,GO:1901700 - 0.000000000000000000000000000003358 130.0
HFD2_k127_7742397_41 succinate dehydrogenase K00242 - - 0.00000000000000000000000000001071 129.0
HFD2_k127_7742397_42 - - - - 0.0000000000000000000000000000618 127.0
HFD2_k127_7742397_43 phosphoglycerate mutase - - - 0.0000000000000000000000000003396 124.0
HFD2_k127_7742397_44 - - - - 0.0000000000000000000000000006811 119.0
HFD2_k127_7742397_45 Protein of unknown function (DUF2905) - - - 0.00000000000000000000002236 100.0
HFD2_k127_7742397_46 - - - - 0.0000000000000000000001227 101.0
HFD2_k127_7742397_47 Protein of unknown function (DUF3126) - - - 0.0000000000000000000213 94.0
HFD2_k127_7742397_48 Bacterial protein of unknown function (Gcw_chp) - - - 0.00000000000000000004814 99.0
HFD2_k127_7742397_49 - - - - 0.0000000000000000000504 100.0
HFD2_k127_7742397_5 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 476.0
HFD2_k127_7742397_51 Amidase K01457 - 3.5.1.54 0.000000000000000004216 87.0
HFD2_k127_7742397_52 membrane - - - 0.000000000004038 72.0
HFD2_k127_7742397_53 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000009089 63.0
HFD2_k127_7742397_54 PFAM conserved - - - 0.0000103 53.0
HFD2_k127_7742397_6 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 472.0
HFD2_k127_7742397_7 COG0477 Permeases of the major facilitator superfamily K03535 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009887 445.0
HFD2_k127_7742397_8 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00015 - 1.1.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004557 417.0
HFD2_k127_7742397_9 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 416.0
HFD2_k127_7775193_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 3.223e-260 812.0
HFD2_k127_7775193_1 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000002665 115.0
HFD2_k127_7775193_2 - - - - 0.0000000003303 64.0
HFD2_k127_7809838_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 1.118e-316 1000.0
HFD2_k127_7809838_1 Elongator protein 3, MiaB family, Radical SAM - - - 3.727e-246 769.0
HFD2_k127_7809838_10 homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 458.0
HFD2_k127_7809838_11 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003799 450.0
HFD2_k127_7809838_12 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446,K11532 - 3.1.3.11,3.1.3.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 418.0
HFD2_k127_7809838_13 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000371 396.0
HFD2_k127_7809838_14 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009574 375.0
HFD2_k127_7809838_15 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 373.0
HFD2_k127_7809838_16 XdhC Rossmann domain K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008085 349.0
HFD2_k127_7809838_17 Transcriptional regulatory protein, C terminal K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 325.0
HFD2_k127_7809838_18 Sir2 family K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 328.0
HFD2_k127_7809838_19 PFAM Carbamoyltransferase K00612 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 322.0
HFD2_k127_7809838_2 Pyridine nucleotide-disulphide oxidoreductase K05297 - 1.18.1.1 3.252e-232 728.0
HFD2_k127_7809838_20 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005338 308.0
HFD2_k127_7809838_21 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008476 307.0
HFD2_k127_7809838_22 Transcriptional regulatory protein, C terminal K02483,K07665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 296.0
HFD2_k127_7809838_23 serine-type endopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 290.0
HFD2_k127_7809838_24 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001437 268.0
HFD2_k127_7809838_25 Adenylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000409 265.0
HFD2_k127_7809838_26 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000002756 241.0
HFD2_k127_7809838_27 TonB dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000002141 268.0
HFD2_k127_7809838_28 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000008831 248.0
HFD2_k127_7809838_29 TonB dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000001896 220.0
HFD2_k127_7809838_3 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 9.104e-218 694.0
HFD2_k127_7809838_30 Cold shock protein domain K03704 - - 0.00000000000000000000000000000000000000000000000000001804 194.0
HFD2_k127_7809838_31 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000001181 198.0
HFD2_k127_7809838_32 Glutamine cyclotransferase K00683 - 2.3.2.5 0.000000000000000000000000000000000000000000000002171 184.0
HFD2_k127_7809838_33 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000002841 196.0
HFD2_k127_7809838_34 MAPEG family - - - 0.0000000000000000000000000000000000000000002306 164.0
HFD2_k127_7809838_35 - - - - 0.000000000000000000000000000000000000000002231 162.0
HFD2_k127_7809838_36 Carbon monoxide dehydrogenase subunit G (CoxG) K09386 - - 0.0000000000000000000000000000000000000002776 156.0
HFD2_k127_7809838_37 Putative FMN-binding domain K07734 - - 0.0000000000000000000000000000000000007227 147.0
HFD2_k127_7809838_38 COG0822 NifU homolog involved in Fe-S cluster formation - - - 0.0000000000000000000002214 103.0
HFD2_k127_7809838_39 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000003903 109.0
HFD2_k127_7809838_4 Dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 614.0
HFD2_k127_7809838_40 Cold shock protein domain K03704 - - 0.00000000000000000000891 94.0
HFD2_k127_7809838_41 PFAM Uncharacterised protein family (UPF0153) - - - 0.00000000000000000001937 99.0
HFD2_k127_7809838_42 PFAM beta-lactamase - - - 0.00000000000001305 87.0
HFD2_k127_7809838_43 - - - - 0.000000000001381 73.0
HFD2_k127_7809838_45 - - - - 0.00000005093 59.0
HFD2_k127_7809838_46 Peptidase propeptide and YPEB domain - - - 0.00000006996 62.0
HFD2_k127_7809838_47 COG1247 Sortase and related acyltransferases K03823 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 2.3.1.183 0.0000747 47.0
HFD2_k127_7809838_5 Aminotransferase K14261 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007968 599.0
HFD2_k127_7809838_6 Probable molybdopterin binding domain K07141 - 2.7.7.76 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 562.0
HFD2_k127_7809838_7 Cupin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 527.0
HFD2_k127_7809838_8 TIGRFAM single-stranded-DNA-specific exonuclease RecJ K07462 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008297,GO:0008409,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0035312,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0045145,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 518.0
HFD2_k127_7809838_9 Beta-eliminating lyase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 470.0
HFD2_k127_7811723_0 PQQ-like domain K00114,K20937 - 1.1.2.8,1.1.5.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004497 600.0
HFD2_k127_7811723_1 Lanthionine synthetase C-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006401 547.0
HFD2_k127_7811723_10 - - - - 0.0000000000000000000000000000000000006776 154.0
HFD2_k127_7811723_11 - - - - 0.00000000000000000000000000000000007734 149.0
HFD2_k127_7811723_12 - - - - 0.00000000000000000000000000000000008399 150.0
HFD2_k127_7811723_13 - - - - 0.00000000000000000000005722 106.0
HFD2_k127_7811723_14 Phosphoenolpyruvate phosphomutase - - - 0.00000000000000000000419 107.0
HFD2_k127_7811723_15 - - - - 0.00000000000000000002506 98.0
HFD2_k127_7811723_16 - - - - 0.00000000000002013 76.0
HFD2_k127_7811723_17 endoribonuclease L-PSP - - - 0.000000129 61.0
HFD2_k127_7811723_2 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008038 309.0
HFD2_k127_7811723_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003535 284.0
HFD2_k127_7811723_4 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001696 267.0
HFD2_k127_7811723_5 Metal-dependent hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001172 254.0
HFD2_k127_7811723_6 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005507 250.0
HFD2_k127_7811723_7 - - - - 0.000000000000000000000000000000000000000002166 159.0
HFD2_k127_7811723_8 - - - - 0.000000000000000000000000000000000000007809 151.0
HFD2_k127_7811723_9 - - - - 0.00000000000000000000000000000000000032 155.0
HFD2_k127_7818157_0 Baseplate J-like protein - - - 0.0 1022.0
HFD2_k127_7818157_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004587 442.0
HFD2_k127_7818157_2 Ceramidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005213 362.0
HFD2_k127_7818157_3 Astacin (Peptidase family M12A) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002674 284.0
HFD2_k127_7818157_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004091 270.0
HFD2_k127_7818157_5 Tail protein - - - 0.0000000000000000000000000000000000000000000000000000000000001281 217.0
HFD2_k127_7818157_6 - - - - 0.0000000000000000000000000000000004643 146.0
HFD2_k127_7818157_7 - - - - 0.00000000000000000000000002166 128.0
HFD2_k127_7847407_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003751 407.0
HFD2_k127_7847407_1 Ribosomal protein L9, N-terminal domain K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000005932 221.0
HFD2_k127_7847407_2 rRNA binding K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000006082 149.0
HFD2_k127_7847407_3 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000007806 137.0
HFD2_k127_7847407_4 PQQ-like domain K17713 - - 0.0000000000000000000000000000001366 135.0
HFD2_k127_7847407_5 Tetratricopeptide repeat-like domain - - - 0.000000000000000000000000000003663 128.0
HFD2_k127_7847407_6 - - - - 0.00000000000000000000001016 106.0
HFD2_k127_7854616_0 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002285 355.0
HFD2_k127_7854616_1 Sugar (and other) transporter K08195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007366 335.0
HFD2_k127_7854616_10 - - - - 0.00000000000000000000000001873 120.0
HFD2_k127_7854616_12 helix_turn_helix isocitrate lyase regulation - - - 0.000000000000000000001159 105.0
HFD2_k127_7854616_13 - - - - 0.000000000000000001126 97.0
HFD2_k127_7854616_14 PASTA K12132 - 2.7.11.1 0.000000000000000002777 99.0
HFD2_k127_7854616_15 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.0000000000000431 72.0
HFD2_k127_7854616_16 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000344 70.0
HFD2_k127_7854616_2 Sugar (and other) transporter K08195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005083 322.0
HFD2_k127_7854616_3 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 313.0
HFD2_k127_7854616_4 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002525 254.0
HFD2_k127_7854616_5 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000007869 225.0
HFD2_k127_7854616_6 gluconolactonase activity K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000003201 173.0
HFD2_k127_7854616_7 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000002825 173.0
HFD2_k127_7854616_8 Amidohydrolase K03392 - 4.1.1.45 0.0000000000000000000000000000000000000002548 163.0
HFD2_k127_7854616_9 Transcriptional regulator K02624,K13641,K21602 - - 0.00000000000000000000000000009173 126.0
HFD2_k127_7883555_0 diguanylate cyclase K02488 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 566.0
HFD2_k127_7883555_1 pyrroloquinoline quinone binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 514.0
HFD2_k127_7883555_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006706 316.0
HFD2_k127_7883555_3 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000007899 251.0
HFD2_k127_7883555_4 Response regulator receiver domain K11443 - - 0.000000000000000000000000000000000000000000000000000000000000001119 220.0
HFD2_k127_7883555_5 Cytochrome B561 K12262 - - 0.0003676 45.0
HFD2_k127_7893012_0 Aldo keto K06221 - 1.1.1.346 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008541 466.0
HFD2_k127_7893012_1 YCII-related domain - - - 0.000000000000000000000000000000000000000000000000000000005595 199.0
HFD2_k127_7897534_0 PEP-utilising enzyme, TIM barrel domain K01007 - 2.7.9.2 0.0 1287.0
HFD2_k127_7897534_1 COG0577 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0 1124.0
HFD2_k127_7897534_10 Acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000003405 268.0
HFD2_k127_7897534_11 SMP-30/Gluconolaconase/LRE-like region - - - 0.0000000000000000000000000000000000000000000000000000000000000000184 235.0
HFD2_k127_7897534_12 Crp-like helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000527 230.0
HFD2_k127_7897534_14 Sodium hydrogen exchanger - - - 0.000000000001075 70.0
HFD2_k127_7897534_15 ABC-type dipeptide transport system periplasmic component K02035 - - 0.00000000009036 62.0
HFD2_k127_7897534_16 Protein of unknown function (DUF2934) - - - 0.00000002771 59.0
HFD2_k127_7897534_2 Carbohydrate phosphorylase K00688 - 2.4.1.1 1.059e-247 776.0
HFD2_k127_7897534_3 Elongator protein 3, MiaB family, Radical SAM - - - 3.989e-224 709.0
HFD2_k127_7897534_4 choline dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 512.0
HFD2_k127_7897534_5 RND family efflux transporter, MFP subunit K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 497.0
HFD2_k127_7897534_6 COG2230 Cyclopropane fatty acid synthase and related methyltransferases K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 499.0
HFD2_k127_7897534_7 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009523 420.0
HFD2_k127_7897534_8 COG1136 ABC-type antimicrobial peptide transport system ATPase component K02003,K05685 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005221 365.0
HFD2_k127_7897534_9 belongs to the carbohydrate kinase PfkB family K16370 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003528 324.0
HFD2_k127_7904831_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 6.908e-214 674.0
HFD2_k127_7904831_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 563.0
HFD2_k127_7904831_2 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 522.0
HFD2_k127_7904831_3 PQQ-like domain K17713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 340.0
HFD2_k127_7904831_4 KR domain - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0008152,GO:0009056,GO:0016491,GO:0044464,GO:0055114,GO:0071704,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006242 310.0
HFD2_k127_7904831_5 - - - - 0.000000000000000000000000000000000000001424 153.0
HFD2_k127_7904831_6 Colicin V production protein K03558 - - 0.000000000000000000000000005243 118.0
HFD2_k127_7904831_7 - - - - 0.000000000001136 76.0
HFD2_k127_7904831_8 COG2826 Transposase and inactivated derivatives, IS30 family - - - 0.00005441 46.0
HFD2_k127_7904860_0 acyl-CoA dehydrogenase - - - 9.664e-211 660.0
HFD2_k127_7904860_1 Phosphoenolpyruvate phosphomutase - - - 0.00000000000000000000005171 113.0
HFD2_k127_7904860_2 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 0.00009551 44.0
HFD2_k127_7904936_0 NAD(P)-binding Rossmann-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 410.0
HFD2_k127_7904936_2 2-dehydropantoate 2-reductase K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 377.0
HFD2_k127_7904936_3 Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate K00452 - 1.13.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000008419 257.0
HFD2_k127_7904936_5 Ornithine cyclodeaminase K01750 - 4.3.1.12 0.000000000000000000000000000000000000000004835 168.0
HFD2_k127_7904936_6 - - - - 0.000000000000000000000001015 116.0
HFD2_k127_7904936_7 peptidase inhibitor activity - - - 0.00000000000000000000002176 113.0
HFD2_k127_7904936_8 COG2826 Transposase and inactivated derivatives, IS30 family - - - 0.00003024 47.0
HFD2_k127_7912803_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001122 271.0
HFD2_k127_7912803_1 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000000000000000000009935 170.0
HFD2_k127_7912803_2 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000000000002 155.0
HFD2_k127_7918736_0 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 541.0
HFD2_k127_7918736_1 leucine-zipper of insertion element IS481 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 540.0
HFD2_k127_7918736_2 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - 0.000000007043 57.0
HFD2_k127_7937988_0 COG2804 Type II secretory pathway ATPase PulE Tfp pilus assembly pathway ATPase PilB K02454,K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 365.0
HFD2_k127_7952665_0 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005033 284.0
HFD2_k127_7952665_1 oxidation-reduction process - - - 0.000000000000000000000001478 118.0
HFD2_k127_7952665_2 endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000003245 79.0
HFD2_k127_7968136_0 peptidase activity - - - 5.897e-194 616.0
HFD2_k127_7968136_1 Domain of unknown function (DUF4091) - - - 0.000000000000004307 77.0
HFD2_k127_7975946_0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 302.0
HFD2_k127_7975946_1 Peptidylprolyl isomerase K01802,K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000111 256.0
HFD2_k127_7975946_2 cheY-homologous receiver domain - - - 0.00001479 50.0
HFD2_k127_7978798_0 Methionine synthase K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.0 1663.0
HFD2_k127_7978798_1 ABC transporter K15738 - - 8.196e-284 880.0
HFD2_k127_7978798_10 ABC transporter K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000002088 255.0
HFD2_k127_7978798_11 ABC-type Fe3 -hydroxamate transport system, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000286 209.0
HFD2_k127_7978798_12 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000004121 196.0
HFD2_k127_7978798_13 carboxymuconolactone decarboxylase - - - 0.0000000000000000000000000000000000008373 142.0
HFD2_k127_7978798_14 MlaC protein K07323 - - 0.0000000000000000000000000000009076 132.0
HFD2_k127_7978798_15 COG2755 Lysophospholipase L1 and related - - - 0.00000000000000005068 83.0
HFD2_k127_7978798_16 Subtilase family - - - 0.00002293 56.0
HFD2_k127_7978798_2 4Fe-4S single cluster domain K06937 - - 8.663e-224 701.0
HFD2_k127_7978798_3 receptor K16092 - - 5.073e-194 626.0
HFD2_k127_7978798_4 L-carnitine dehydratase bile acid-inducible protein F K18289 - 2.8.3.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004177 435.0
HFD2_k127_7978798_5 Methylenetetrahydrofolate reductase K00297 GO:0003674,GO:0003824,GO:0004489,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 404.0
HFD2_k127_7978798_6 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008143 371.0
HFD2_k127_7978798_7 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000465 342.0
HFD2_k127_7978798_8 MlaA lipoprotein K04754 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000175 274.0
HFD2_k127_7978798_9 PepSY-associated TM region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004073 279.0
HFD2_k127_7980900_0 Integrase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 479.0
HFD2_k127_7980900_1 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002329 244.0
HFD2_k127_7980900_2 regulation of DNA-templated transcription, elongation - - - 0.00000000000000000000000000000000000000000000000003091 195.0
HFD2_k127_7980900_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000001553 118.0
HFD2_k127_7980900_4 Phasin protein - - - 0.000000000000000001199 93.0
HFD2_k127_7980900_5 - - - - 0.0000000988 61.0
HFD2_k127_7980900_6 penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 0.00004754 45.0
HFD2_k127_8012084_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 4.633e-205 650.0
HFD2_k127_8012084_1 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 577.0
HFD2_k127_8012084_10 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004986 289.0
HFD2_k127_8012084_11 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000008199 272.0
HFD2_k127_8012084_12 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007576 268.0
HFD2_k127_8012084_13 Divergent polysaccharide deacetylase K09798 - - 0.00000000000000000000000000000000000000000000000000000000000000000001243 246.0
HFD2_k127_8012084_14 sigma factor activity K02405,K03086,K03087,K03090 - - 0.00000000000000000000000000000000000000000000000000000000000000003303 238.0
HFD2_k127_8012084_15 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.0000000000000000000000000000000000000000000000000000000005368 206.0
HFD2_k127_8012084_16 Flagellar basal body rod FlgEFG protein C-terminal K02391,K02392 - - 0.00000000000000000000000000000000000000000000000000000001482 209.0
HFD2_k127_8012084_17 Peptidase family M23 - - - 0.00000000000000000000000000000000000009265 162.0
HFD2_k127_8012084_18 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.0000000000000000000000000000002098 131.0
HFD2_k127_8012084_19 PFAM MgtE intracellular - - - 0.00000000000000000000000336 113.0
HFD2_k127_8012084_2 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 544.0
HFD2_k127_8012084_20 Rod binding protein - - - 0.0000000000000000004689 101.0
HFD2_k127_8012084_21 Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly K02386 - - 0.0000000000000006512 84.0
HFD2_k127_8012084_22 - - - - 0.0000000008037 64.0
HFD2_k127_8012084_23 - - - - 0.0007176 49.0
HFD2_k127_8012084_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 540.0
HFD2_k127_8012084_4 tail specific protease K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 499.0
HFD2_k127_8012084_5 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 GO:0005575,GO:0005623,GO:0009288,GO:0009425,GO:0042597,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 488.0
HFD2_k127_8012084_6 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007994 442.0
HFD2_k127_8012084_7 Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase K07257 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 398.0
HFD2_k127_8012084_8 Belongs to the flagella basal body rod proteins family K02392 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009309 332.0
HFD2_k127_8012084_9 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001861 284.0
HFD2_k127_8032799_0 Ketoacyl-synthetase C-terminal extension - - - 3.544e-320 1002.0
HFD2_k127_8047297_0 Trifunctional enzyme subunit alpha K07514,K07515 - 1.1.1.211,1.1.1.35,4.2.1.17,5.3.3.8 1.707e-265 837.0
HFD2_k127_8047297_1 Thiolase, N-terminal domain K00626 GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006725,GO:0006805,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016020,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019439,GO:0019748,GO:0019752,GO:0030258,GO:0030312,GO:0032787,GO:0033554,GO:0033812,GO:0034440,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0071944,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 603.0
HFD2_k127_8047297_10 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000004851 113.0
HFD2_k127_8047297_11 PIN domain - - - 0.000000000000000000000001608 107.0
HFD2_k127_8047297_12 Protein of unknown function (DUF1491) - - - 0.0000000000000000000000724 102.0
HFD2_k127_8047297_14 Response regulator, receiver K07677,K07679,K20974 - 2.7.13.3 0.00000001109 64.0
HFD2_k127_8047297_15 von Willebrand factor, type A K07114 - - 0.000001239 52.0
HFD2_k127_8047297_17 - - - - 0.00003167 49.0
HFD2_k127_8047297_18 Plasmid stability protein K21495 - - 0.0008026 49.0
HFD2_k127_8047297_2 Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 497.0
HFD2_k127_8047297_3 Nucleoside transporter K03317 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 477.0
HFD2_k127_8047297_4 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 372.0
HFD2_k127_8047297_5 Histidine kinase K11357 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 340.0
HFD2_k127_8047297_6 Lysophospholipase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003168 279.0
HFD2_k127_8047297_7 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000957 254.0
HFD2_k127_8047297_8 Receptor family ligand binding region - - - 0.0000000000000000000000000000000000000000000000000000000000000002516 236.0
HFD2_k127_8047297_9 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000002293 228.0
HFD2_k127_8059580_0 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000001965 217.0
HFD2_k127_8059580_1 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000006446 220.0
HFD2_k127_8085105_0 - - - - 3.335e-269 851.0
HFD2_k127_8085105_1 Domain of unknown function (DUF4166) - - - 1.482e-229 723.0
HFD2_k127_8085105_10 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0043814,GO:0044237,GO:0044249,GO:0051186,GO:0051188,GO:0070568 2.7.7.68 0.000000000000119 81.0
HFD2_k127_8085105_2 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 428.0
HFD2_k127_8085105_3 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11779,K11784 - 1.21.98.1,2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008329 414.0
HFD2_k127_8085105_4 Integrase core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 395.0
HFD2_k127_8085105_5 TIGRFAM LPPG domain protein containing protein K11212 - 2.7.8.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003433 325.0
HFD2_k127_8085105_6 dienelactone hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000003417 229.0
HFD2_k127_8085105_7 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000001548 155.0
HFD2_k127_8085105_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000005625 155.0
HFD2_k127_8085105_9 Protein of unknown function, DUF393 - - - 0.00000000000000001986 83.0
HFD2_k127_8122546_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008898 500.0
HFD2_k127_8122546_1 Belongs to the flagella basal body rod proteins family K02396 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003587 480.0
HFD2_k127_8122546_2 Bacterial flagellin C-terminal helical region K02397 - - 0.00000000000000000000000000000000000000000002113 173.0
HFD2_k127_8122546_3 Flagellar hook-length control protein FliK K02414,K10565 - - 0.00000000003539 76.0
HFD2_k127_8154889_0 COG1042 Acyl-CoA synthetase (NDP forming) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003344 575.0
HFD2_k127_8154889_1 dehydratase - - - 0.000000000005337 72.0
HFD2_k127_8187147_0 Two component transcriptional regulator, winged helix family K07658 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 301.0
HFD2_k127_8187147_1 4 iron, 4 sulfur cluster binding K00528,K02574,K07098 - 1.18.1.2,1.19.1.1 0.00000000000001301 81.0
HFD2_k127_8187147_2 histidine kinase A domain protein K02484 - 2.7.13.3 0.00001934 48.0
HFD2_k127_8262548_0 E1-E2 ATPase K01535 - 3.6.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004631 550.0
HFD2_k127_8262548_1 Universal stress protein family - - - 0.000000000000000000000000000000000000001067 153.0
HFD2_k127_8262548_2 - - - - 0.000000000000000000000000000000000000002238 147.0
HFD2_k127_8262548_3 Sulphur transport - - - 0.00000000000000000002389 92.0
HFD2_k127_8262548_4 Sulphur transport K07112 - - 0.000000001415 61.0
HFD2_k127_8291320_0 protein related to plant photosystem II stability assembly factor - - - 1.375e-215 673.0
HFD2_k127_8291320_1 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 432.0
HFD2_k127_8291320_2 - - - - 0.0000000000000000000000000000000000000000000000003638 190.0
HFD2_k127_8291320_3 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000000004906 158.0
HFD2_k127_8291320_4 PFAM Sel1 domain protein repeat-containing protein K07126 - - 0.00000000000000000000000000000000000003746 150.0
HFD2_k127_8291320_5 ThiS family K03636 - - 0.000000000000000000000000000000003358 129.0
HFD2_k127_8291320_6 Histidine phosphatase superfamily (branch 1) - - - 0.0000000000000000000001032 106.0
HFD2_k127_8291320_7 Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases. - - - 0.0000000000000002096 83.0
HFD2_k127_8291320_8 Transposase K11904 - - 0.000000002533 60.0
HFD2_k127_8291320_9 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0004226 45.0
HFD2_k127_8293105_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 610.0
HFD2_k127_8293105_1 transposition, DNA-mediated - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 316.0
HFD2_k127_8293105_2 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.0000000000000000000000006916 108.0
HFD2_k127_8293105_3 TOBE domain - - - 0.000000000000000000000003595 103.0
HFD2_k127_8315560_0 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000002242 230.0
HFD2_k127_8315560_1 Nitrile hydratase beta subunit K20807 - 4.2.1.84 0.000000000000000000000002086 105.0
HFD2_k127_8315560_2 Nitrile hydratase beta subunit K20807 - 4.2.1.84 0.00000001394 60.0
HFD2_k127_8334824_0 GDP-mannose mannosyl hydrolase activity K00077,K01092,K03574 - 1.1.1.169,3.1.3.25,3.6.1.55 0.0000000000000000000000161 108.0
HFD2_k127_8334824_1 - - - - 0.000000000000006455 79.0
HFD2_k127_8334824_2 DoxX-like family - - - 0.000000188 58.0
HFD2_k127_8334824_3 - - - - 0.00000134 57.0
HFD2_k127_8367447_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 4.201e-243 762.0
HFD2_k127_8367447_1 Gentisate 1,2-dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004339 539.0
HFD2_k127_8367447_10 Flavodoxin-like fold K19784 - - 0.0000000000000000000000000000000000000000000000000000000000000001626 226.0
HFD2_k127_8367447_12 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000161 205.0
HFD2_k127_8367447_13 HxlR-like helix-turn-helix - - - 0.0000000000000000000000000000000000000000000000622 172.0
HFD2_k127_8367447_14 protein conserved in bacteria - - - 0.000000000000000000000000000000004035 132.0
HFD2_k127_8367447_15 - - - - 0.0000000000000000000000000000005571 124.0
HFD2_k127_8367447_16 Phage derived protein Gp49-like (DUF891) - - - 0.00000000000000000805 83.0
HFD2_k127_8367447_17 Metallo-beta-lactamase superfamily - - - 0.00000000000000007147 90.0
HFD2_k127_8367447_18 - - - - 0.000000000000003859 80.0
HFD2_k127_8367447_2 Acetamidase/Formamidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005192 438.0
HFD2_k127_8367447_20 cheY-homologous receiver domain - - - 0.00003569 49.0
HFD2_k127_8367447_3 4-hydroxy-tetrahydrodipicolinate synthase K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005643 372.0
HFD2_k127_8367447_4 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000864 337.0
HFD2_k127_8367447_5 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006975 290.0
HFD2_k127_8367447_6 class II Aldolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007271 273.0
HFD2_k127_8367447_7 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000003001 272.0
HFD2_k127_8367447_8 Amidohydrolase family K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000005447 243.0
HFD2_k127_8367447_9 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000000000000002589 231.0
HFD2_k127_8375855_0 PFAM glycosyl transferase family 20 K00697 - 2.4.1.15,2.4.1.347 1.406e-309 964.0
HFD2_k127_8375855_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 1.374e-271 857.0
HFD2_k127_8375855_10 dehydrogenase E1 component K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008175 428.0
HFD2_k127_8375855_11 Predicted membrane protein (DUF2207) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005177 439.0
HFD2_k127_8375855_12 Transcriptional regulatory protein, C terminal K02483,K13584 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006658 411.0
HFD2_k127_8375855_13 Sodium proton antiporter, NhaD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 434.0
HFD2_k127_8375855_14 2-oxoacid dehydrogenases acyltransferase (catalytic domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 399.0
HFD2_k127_8375855_15 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 401.0
HFD2_k127_8375855_16 PFAM SPFH domain Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 374.0
HFD2_k127_8375855_17 mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 331.0
HFD2_k127_8375855_18 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003816 311.0
HFD2_k127_8375855_19 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005401 313.0
HFD2_k127_8375855_2 Glycosyl hydrolases family 15 - - - 1.657e-267 834.0
HFD2_k127_8375855_20 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 304.0
HFD2_k127_8375855_21 Inositol monophosphatase family K01082 - 3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006543 289.0
HFD2_k127_8375855_22 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 288.0
HFD2_k127_8375855_23 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 292.0
HFD2_k127_8375855_24 ATPases associated with a variety of cellular activities K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002082 282.0
HFD2_k127_8375855_25 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001789 273.0
HFD2_k127_8375855_26 D-alanine--D-alanine ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006161 259.0
HFD2_k127_8375855_27 COG4770 Acetyl propionyl-CoA carboxylase, alpha subunit K01968 - 6.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000006756 259.0
HFD2_k127_8375855_29 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009867 252.0
HFD2_k127_8375855_3 Belongs to the UbiD family K03182 - 4.1.1.98 3.694e-255 796.0
HFD2_k127_8375855_30 Protein of unknown function (DUF1194) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001164 250.0
HFD2_k127_8375855_31 PFAM SMP-30 Gluconolaconase K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000009437 253.0
HFD2_k127_8375855_32 Protein of unknown function (DUF1134) - - - 0.000000000000000000000000000000000000000000000000000000000000000001504 231.0
HFD2_k127_8375855_33 Pfam SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000002348 237.0
HFD2_k127_8375855_34 lactoylglutathione lyase activity K03088 - - 0.000000000000000000000000000000000000000000000000000000000000003267 238.0
HFD2_k127_8375855_35 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000004517 215.0
HFD2_k127_8375855_36 YCII-related domain - - - 0.000000000000000000000000000000000000000000000000000000000969 205.0
HFD2_k127_8375855_37 3-demethylubiquinone-9 3-methyltransferase K04750 - - 0.000000000000000000000000000000000000000000000000000000001641 202.0
HFD2_k127_8375855_38 transferase activity, transferring acyl groups other than amino-acyl groups K11941 - - 0.0000000000000000000000000000000000000000000000000000002896 209.0
HFD2_k127_8375855_39 signal transduction histidine kinase K13588 - - 0.000000000000000000000000000000000000000000000000000002899 197.0
HFD2_k127_8375855_4 Belongs to the sigma-70 factor family. ECF subfamily - - - 3.024e-207 651.0
HFD2_k127_8375855_40 Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate K00452 - 1.13.11.6 0.0000000000000000000000000000000000000000000000000009108 190.0
HFD2_k127_8375855_41 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.000000000000000000000000000000000000000000000000009261 193.0
HFD2_k127_8375855_42 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000000000000000000000000000004974 182.0
HFD2_k127_8375855_43 3-demethylubiquinone-9 3-methyltransferase K04750 - - 0.000000000000000000000000000000000000000000000002306 180.0
HFD2_k127_8375855_44 Predicted membrane protein (DUF2214) K08983 - - 0.000000000000000000000000000000000000000000000008932 175.0
HFD2_k127_8375855_45 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000006121 164.0
HFD2_k127_8375855_46 FOG TPR repeat, SEL1 subfamily K07126,K13582 - - 0.000000000000000000000000000000000000008275 164.0
HFD2_k127_8375855_47 Glycine-zipper domain - - - 0.0000000000000000000000000000000000009994 144.0
HFD2_k127_8375855_48 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.000000000000000000000000000000000009014 149.0
HFD2_k127_8375855_49 YCII-related domain - - - 0.00000000000000000000000000000000001869 139.0
HFD2_k127_8375855_5 flagellum-specific ATP synthase K02412 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 580.0
HFD2_k127_8375855_50 Uncharacterized conserved protein (DUF2277) - - - 0.0000000000000000000000000000001734 124.0
HFD2_k127_8375855_51 YCII-related domain - - - 0.000000000000000000000000000000467 135.0
HFD2_k127_8375855_52 Exopolysaccharide synthesis ExoD - - - 0.0000000000000000000000000000006976 131.0
HFD2_k127_8375855_53 Protein of unknown function (DUF2390) - - - 0.00000000000000000000000000003002 123.0
HFD2_k127_8375855_54 acetyltransferase - - - 0.0000000000000000000000000001649 121.0
HFD2_k127_8375855_55 Protein of unknown function (DUF433) - - - 0.00000000000000000000000002253 109.0
HFD2_k127_8375855_56 - - - - 0.00000000000000000000001747 102.0
HFD2_k127_8375855_57 MlaD protein K02067 - - 0.00000000000000000000004254 110.0
HFD2_k127_8375855_58 - - - - 0.00000000000000000000005374 110.0
HFD2_k127_8375855_59 - - - - 0.0000000000000000000003103 108.0
HFD2_k127_8375855_6 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase K00162,K21417 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 464.0
HFD2_k127_8375855_60 Membrane protein implicated in regulation of membrane protease activity K07340 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000005371 102.0
HFD2_k127_8375855_61 - - - - 0.00000000000000003708 81.0
HFD2_k127_8375855_62 flagellar export protein FliJ - - - 0.000000000000002993 81.0
HFD2_k127_8375855_63 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.000000000000005524 83.0
HFD2_k127_8375855_64 DoxX K15977 - - 0.000000000000009874 79.0
HFD2_k127_8375855_65 PAAR motif K11904 - - 0.0000000000000283 82.0
HFD2_k127_8375855_66 - - - - 0.00000001066 61.0
HFD2_k127_8375855_67 peptidyl-tyrosine sulfation - - - 0.0000133 57.0
HFD2_k127_8375855_68 Cell division protein - - - 0.00003073 56.0
HFD2_k127_8375855_69 ABC-type transport auxiliary lipoprotein component K18480 - - 0.00007617 54.0
HFD2_k127_8375855_7 acyl-CoA transferases carnitine dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004066 462.0
HFD2_k127_8375855_8 Belongs to the thiolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 441.0
HFD2_k127_8375855_9 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005262 429.0
HFD2_k127_8376681_0 PFAM Glyoxalase bleomycin resistance protein dioxygenase K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000001234 258.0
HFD2_k127_8376681_1 PFAM PilT protein domain protein - - - 0.000000000000000000000000000000000000000000003712 168.0
HFD2_k127_8376681_2 COG NOG14600 non supervised orthologous group - - - 0.00000000000000000000000000000000000001907 144.0
HFD2_k127_8376681_3 PFAM Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000006505 149.0
HFD2_k127_8376681_4 Putative zinc- or iron-chelating domain - - - 0.0000000000000000000001289 108.0
HFD2_k127_8376681_5 SpoVT / AbrB like domain - - - 0.00000000000000000005986 92.0
HFD2_k127_8376681_6 Haem-degrading - - - 0.00000000005786 72.0
HFD2_k127_8376681_7 transposase activity K07483 - - 0.00000001025 61.0
HFD2_k127_8376681_8 Haem-degrading K11477 - - 0.0000003558 60.0
HFD2_k127_8376681_9 Transposase K07483 - - 0.000108 48.0
HFD2_k127_8397588_0 PFAM Glycosyl transferase family 2 - - - 3.116e-250 798.0
HFD2_k127_8397588_1 Major facilitator Superfamily - - - 6.798e-222 692.0
HFD2_k127_8397588_10 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005518 312.0
HFD2_k127_8397588_11 Methyltransferase FkbM domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002415 244.0
HFD2_k127_8397588_12 Acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000005991 215.0
HFD2_k127_8397588_13 T4-like virus tail tube protein gp19 - - - 0.00000000000000000000000000000000000000002266 156.0
HFD2_k127_8397588_14 Domain of unknown function (DUF4395) - - - 0.000000000000000000000000000000000000001696 152.0
HFD2_k127_8397588_15 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000004015 144.0
HFD2_k127_8397588_16 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity - - - 0.00000000000000000000000000000000000708 144.0
HFD2_k127_8397588_17 - - - - 0.0000000000000000000000000000769 126.0
HFD2_k127_8397588_18 - - - - 0.000000000000000000000005228 112.0
HFD2_k127_8397588_19 - - - - 0.0000000000000000001022 94.0
HFD2_k127_8397588_2 - K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 426.0
HFD2_k127_8397588_20 - - - - 0.00000000000001536 84.0
HFD2_k127_8397588_21 transferase activity, transferring glycosyl groups - - - 0.000000000003674 69.0
HFD2_k127_8397588_22 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000007159 74.0
HFD2_k127_8397588_23 Methyltransferase domain - - - 0.000000005347 66.0
HFD2_k127_8397588_24 membrane protein (DUF2078) K08982 - - 0.00000002226 58.0
HFD2_k127_8397588_3 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 382.0
HFD2_k127_8397588_4 Outer membrane efflux protein K19123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 377.0
HFD2_k127_8397588_5 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 369.0
HFD2_k127_8397588_6 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 354.0
HFD2_k127_8397588_7 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004733 353.0
HFD2_k127_8397588_8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 328.0
HFD2_k127_8397588_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 332.0
HFD2_k127_8465118_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 1e-323 1006.0
HFD2_k127_8465118_1 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 3.676e-290 900.0
HFD2_k127_8465118_10 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005118 556.0
HFD2_k127_8465118_11 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 513.0
HFD2_k127_8465118_12 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 505.0
HFD2_k127_8465118_13 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 512.0
HFD2_k127_8465118_14 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004504 500.0
HFD2_k127_8465118_15 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003216 486.0
HFD2_k127_8465118_16 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005125 450.0
HFD2_k127_8465118_17 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 452.0
HFD2_k127_8465118_18 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01928,K01929,K15792 - 6.3.2.10,6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007484 445.0
HFD2_k127_8465118_19 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 439.0
HFD2_k127_8465118_2 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 1.196e-286 900.0
HFD2_k127_8465118_20 COG0768 Cell division protein FtsI penicillin-binding protein 2 K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004113 432.0
HFD2_k127_8465118_21 HflC and HflK could encode or regulate a protease K04088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 416.0
HFD2_k127_8465118_22 D-ala D-ala ligase N-terminus K00075,K01921 - 1.3.1.98,6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 419.0
HFD2_k127_8465118_23 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008064 393.0
HFD2_k127_8465118_24 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003227 373.0
HFD2_k127_8465118_25 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 360.0
HFD2_k127_8465118_26 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 347.0
HFD2_k127_8465118_27 Coenzyme A transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009405 330.0
HFD2_k127_8465118_28 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 333.0
HFD2_k127_8465118_29 HflC and HflK could regulate a protease K04087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005851 328.0
HFD2_k127_8465118_3 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 5.061e-253 785.0
HFD2_k127_8465118_30 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 320.0
HFD2_k127_8465118_31 Coenzyme A transferase K01034 - 2.8.3.8,2.8.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008158 308.0
HFD2_k127_8465118_32 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 295.0
HFD2_k127_8465118_33 phosphoserine phosphatase K01079 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003637 283.0
HFD2_k127_8465118_34 ACT domain K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000002257 256.0
HFD2_k127_8465118_35 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000001874 260.0
HFD2_k127_8465118_36 major pilin protein fima - - - 0.000000000000000000000000000000000000000000000000000000000000000000002706 246.0
HFD2_k127_8465118_37 Ribosomal protein L11 methyltransferase (PrmA) K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000001519 239.0
HFD2_k127_8465118_38 antibiotic catabolic process K13277,K20276 - - 0.0000000000000000000000000000000000000000000000000000000000000000003875 250.0
HFD2_k127_8465118_39 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000000000000000000002693 226.0
HFD2_k127_8465118_4 aminopeptidase K01262 - 3.4.11.9 1.221e-244 769.0
HFD2_k127_8465118_40 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.0000000000000000000000000000000000000000000000000647 182.0
HFD2_k127_8465118_41 Essential cell division protein K03589 - - 0.0000000000000000000000000000000000000001173 162.0
HFD2_k127_8465118_42 Stringent starvation protein B K09985 - - 0.000000000000000000000000000000000000002525 152.0
HFD2_k127_8465118_43 PIN domain K07062 - - 0.00000000000000000000000000000000000000271 150.0
HFD2_k127_8465118_44 Acetyltransferase (GNAT) domain K00657 - 2.3.1.57 0.00000000000000000000000000000000002546 147.0
HFD2_k127_8465118_45 Protein of unknown function (DUF1211) - - - 0.000000000000000000000000000000002176 145.0
HFD2_k127_8465118_46 SnoaL-like domain - - - 0.000000000000000000000000003389 115.0
HFD2_k127_8465118_47 plasmid stabilization protein K21495 - - 0.000000000000000000000000008733 111.0
HFD2_k127_8465118_48 - - - - 0.00000000000000000000000002129 110.0
HFD2_k127_8465118_49 - - - - 0.0000000000000000000001808 108.0
HFD2_k127_8465118_5 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 1.867e-239 752.0
HFD2_k127_8465118_50 - - - - 0.00000000000000002605 86.0
HFD2_k127_8465118_52 - - - - 0.0000000000000003489 85.0
HFD2_k127_8465118_53 - - - - 0.000000000000001939 79.0
HFD2_k127_8465118_54 shape-determining protein K03571 - - 0.000000000000003545 85.0
HFD2_k127_8465118_55 Ribbon-helix-helix domain - - - 0.000000000002644 72.0
HFD2_k127_8465118_56 Domain of unknown function (DUF4169) - - - 0.0000000165 59.0
HFD2_k127_8465118_57 - - - - 0.000001554 52.0
HFD2_k127_8465118_6 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 1.833e-215 693.0
HFD2_k127_8465118_7 COG0768 cell division protein FtsI penicillin-binding protein 2 K05515 - 3.4.16.4 2.335e-199 639.0
HFD2_k127_8465118_8 Belongs to the MurCDEF family K01924 - 6.3.2.8 9.099e-195 636.0
HFD2_k127_8465118_9 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 589.0
HFD2_k127_8470242_0 Beta-eliminating lyase K01738,K01740 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003961,GO:0004124,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006555,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0017144,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0050667,GO:0071265,GO:0071266,GO:0071268,GO:0071269,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47,2.5.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006401 606.0
HFD2_k127_8470242_1 Enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007481 323.0
HFD2_k127_8470242_2 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 327.0
HFD2_k127_8470242_3 MmgE/PrpD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006025 317.0
HFD2_k127_8470242_4 Cyclodeaminase K01750,K19244 - 1.4.1.1,4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000001562 265.0
HFD2_k127_8470242_5 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000998 249.0
HFD2_k127_8470242_6 CoA binding domain K06929 - - 0.000000000000000000000000000000000000000000000000000000000000001154 226.0
HFD2_k127_8470242_7 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000002045 196.0
HFD2_k127_8470242_8 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000377 158.0
HFD2_k127_8470242_9 glucose sorbosone - - - 0.0000000000000000000000000000000000005159 147.0
HFD2_k127_8483580_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 1.253e-263 816.0
HFD2_k127_8483580_1 PFAM Carbamoyl-phosphate synthase L chain, ATP binding domain K01955 - 6.3.5.5 4.65e-233 731.0
HFD2_k127_8483580_10 ferredoxin K04755 - - 0.0000000000000000000000000000000000000000000008542 167.0
HFD2_k127_8483580_11 COG2893 Phosphotransferase system, mannose fructose-specific component IIA K02793 - 2.7.1.191 0.000000000000000000000000000000000000000005661 160.0
HFD2_k127_8483580_12 Protein conserved in bacteria K09973 - - 0.0000000000000000000000000000000000000003318 162.0
HFD2_k127_8483580_13 protein conserved in bacteria K09973 - - 0.000000000000000000000000000000001785 141.0
HFD2_k127_8483580_14 Serine kinase of the HPr protein regulates carbohydrate metabolism K06023 - - 0.00000000000000000000005177 112.0
HFD2_k127_8483580_15 - - - - 0.00000000000000000002079 98.0
HFD2_k127_8483580_16 system phosphocarrier protein HPr K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006808,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0044424,GO:0044464,GO:0050789,GO:0051179,GO:0051234,GO:0065007,GO:0071702 - 0.00000000000000000002356 96.0
HFD2_k127_8483580_17 - - - - 0.000000003282 69.0
HFD2_k127_8483580_18 Cysteine-rich CWC - - - 0.0001461 47.0
HFD2_k127_8483580_2 PAS fold - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 576.0
HFD2_k127_8483580_3 Stimulus-sensing domain K14980 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 445.0
HFD2_k127_8483580_4 Reductase C-terminal K00529 - 1.18.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009944 404.0
HFD2_k127_8483580_5 Transcriptional regulatory protein, C terminal K14981 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005 366.0
HFD2_k127_8483580_6 coenzyme F390 K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 327.0
HFD2_k127_8483580_7 Adenosine/AMP deaminase K01488,K18286,K21053 GO:0000034,GO:0003674,GO:0003824,GO:0006139,GO:0006144,GO:0006145,GO:0006146,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0046083,GO:0046100,GO:0046101,GO:0046112,GO:0046113,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.4.2,3.5.4.4,3.5.4.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007763 293.0
HFD2_k127_8483580_8 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000176 260.0
HFD2_k127_8483580_9 Transcription elongation factor, N-terminal K03624 - - 0.0000000000000000000000000000000000000000000000000000000000000004228 224.0
HFD2_k127_849008_0 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 6.3.4.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006789 366.0
HFD2_k127_849008_1 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000006185 234.0
HFD2_k127_849008_2 Diguanylate cyclase, GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000004219 218.0
HFD2_k127_849008_3 COQ9 K18587 - - 0.0000000000000000000000000000000000000007621 152.0
HFD2_k127_849008_4 small protein containing a coiled-coil domain - - - 0.0000000000000002256 81.0
HFD2_k127_849008_5 small protein - - - 0.000002041 51.0
HFD2_k127_8493292_0 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007983 297.0
HFD2_k127_8493292_1 - - - - 0.00000000000108 71.0
HFD2_k127_851605_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 5.824e-247 772.0
HFD2_k127_851605_1 ABC transporter transmembrane region K06147 GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006996,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009507,GO:0009526,GO:0009536,GO:0009555,GO:0009657,GO:0009658,GO:0009889,GO:0009941,GO:0009987,GO:0010035,GO:0010038,GO:0010288,GO:0010380,GO:0016020,GO:0016043,GO:0018130,GO:0019222,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0019866,GO:0022622,GO:0030003,GO:0031090,GO:0031323,GO:0031326,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0042221,GO:0042592,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0046686,GO:0046916,GO:0048229,GO:0048364,GO:0048731,GO:0048856,GO:0048878,GO:0050789,GO:0050790,GO:0050794,GO:0050801,GO:0050896,GO:0051171,GO:0051186,GO:0051188,GO:0051189,GO:0051193,GO:0051276,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0065009,GO:0071704,GO:0071840,GO:0090056,GO:0090407,GO:0098771,GO:0099402,GO:1901360,GO:1901362,GO:1901401,GO:1901463,GO:1901564,GO:1901566,GO:1901576 - 1.452e-221 706.0
HFD2_k127_851605_2 tRNA synthetases class I (C) catalytic domain K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 537.0
HFD2_k127_851605_3 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000005778 187.0
HFD2_k127_851605_4 Cold shock protein domain K03704 - - 0.00000000000000000000000000000000000000002544 158.0
HFD2_k127_8571709_0 COG4993 Glucose dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008862 563.0
HFD2_k127_8571709_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 503.0
HFD2_k127_8571709_10 - - - - 0.000000000000000000004419 104.0
HFD2_k127_8571709_11 ABC transporter, phosphonate, periplasmic substrate-binding protein K02051 - - 0.000000000001802 76.0
HFD2_k127_8571709_12 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000306 63.0
HFD2_k127_8571709_2 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006053 458.0
HFD2_k127_8571709_3 Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000647 342.0
HFD2_k127_8571709_4 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 296.0
HFD2_k127_8571709_5 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007273 289.0
HFD2_k127_8571709_6 Glutathione S-transferase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001037 270.0
HFD2_k127_8571709_7 Thioredoxin-like domain K03672 - 1.8.1.8 0.000000000000000000000000000000000000000000000000001074 187.0
HFD2_k127_8571709_8 Asp/Glu/Hydantoin racemase K01799 - 5.2.1.1 0.0000000000000000000000000000000124 138.0
HFD2_k127_8571709_9 Domain of unknown function (DUF1330) - - - 0.00000000000000000000000000002019 128.0
HFD2_k127_8575168_0 PFAM transposase IS4 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001823 238.0
HFD2_k127_8575168_1 HNH nucleases - - - 0.00000000000001428 81.0
HFD2_k127_860269_0 Histidine kinase - - - 4.037e-221 714.0
HFD2_k127_860269_1 lysine 2,3-aminomutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004134 589.0
HFD2_k127_860269_10 Belongs to the N(4) N(6)-methyltransferase family K00590 - 2.1.1.113 0.0000000000000000000000000000000000000000000008107 179.0
HFD2_k127_860269_11 Helix-turn-helix K21498 - - 0.00000000000000000000000000000000001327 137.0
HFD2_k127_860269_12 FR47-like protein - - - 0.000000000000000000000000000000002662 137.0
HFD2_k127_860269_13 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.0000000000000000000000000000001169 125.0
HFD2_k127_860269_14 PFAM Lipid A Biosynthesis N-terminal - - - 0.0000000000000000000000000002478 117.0
HFD2_k127_860269_15 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000001919 115.0
HFD2_k127_860269_16 Response regulator receiver - - - 0.000000000000000000002824 104.0
HFD2_k127_860269_17 helix_turn_helix, Lux Regulon K14987 - - 0.0000000000000001921 88.0
HFD2_k127_860269_18 phosphorelay signal transduction system - - - 0.0000000000003496 72.0
HFD2_k127_860269_19 Recombinase zinc beta ribbon domain K06400 - - 0.000003062 52.0
HFD2_k127_860269_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 365.0
HFD2_k127_860269_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 373.0
HFD2_k127_860269_4 Glutathione-dependent formaldehyde-activating enzyme K03396 - 4.4.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007135 310.0
HFD2_k127_860269_5 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 318.0
HFD2_k127_860269_6 CorA-like Mg2+ transporter protein K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003262 314.0
HFD2_k127_860269_7 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000002701 269.0
HFD2_k127_860269_8 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000007146 261.0
HFD2_k127_860269_9 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000002511 246.0
HFD2_k127_8629877_0 Belongs to the UbiD family K03182 - 4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 534.0
HFD2_k127_8629877_1 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 381.0
HFD2_k127_8629877_2 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000001542 209.0
HFD2_k127_8629877_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000000000867 185.0
HFD2_k127_8629877_4 COG0456 Acetyltransferases - - - 0.000000000000000000000000000000000000000000002703 179.0
HFD2_k127_8629877_5 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000002645 131.0
HFD2_k127_8629877_6 Putative 2OG-Fe(II) oxygenase - - - 0.00000000000000000000000000002218 128.0
HFD2_k127_8629877_7 cheY-homologous receiver domain - - - 0.0000000000000000000001728 102.0
HFD2_k127_8629877_8 Bacteriophytochrome (light-regulated signal transduction histidine kinase) - - - 0.0000000000001616 72.0
HFD2_k127_8631206_0 - - - - 0.0 1015.0
HFD2_k127_8631206_1 Belongs to the TPP enzyme family K01576 - 4.1.1.7 1.407e-217 688.0
HFD2_k127_8631206_2 Sugar (and other) transporter K08195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007084 545.0
HFD2_k127_8631206_3 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003624 399.0
HFD2_k127_8631206_4 transcription regulator containing HTH domain K18831 - - 0.00000000000000000000000000000000000000000000004941 173.0
HFD2_k127_8631206_5 peptidyl-tyrosine sulfation - - - 0.00000000000006856 82.0
HFD2_k127_8631206_6 YCII-related domain - - - 0.000000000000201 70.0
HFD2_k127_8683704_0 penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 2.742e-271 857.0
HFD2_k127_8683704_1 Biotin carboxylase K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 2.027e-222 696.0
HFD2_k127_8683704_10 COG1104 Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 337.0
HFD2_k127_8683704_11 hydrolase of the alpha beta superfamily K07018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006192 303.0
HFD2_k127_8683704_12 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004282 290.0
HFD2_k127_8683704_13 FeS assembly protein SufB K09014 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009536,GO:0009842,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000006232 224.0
HFD2_k127_8683704_14 Redoxin K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000004079 210.0
HFD2_k127_8683704_15 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000001719 198.0
HFD2_k127_8683704_16 transcriptional regulator K13643 - - 0.0000000000000000000000000000000000000000000000000000002581 201.0
HFD2_k127_8683704_17 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.00000000000000000000000000000000000000001567 163.0
HFD2_k127_8683704_18 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000000000001737 156.0
HFD2_k127_8683704_19 DoxX family K15977 - - 0.00000000000000000000000000000000000003621 147.0
HFD2_k127_8683704_2 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 1.099e-207 677.0
HFD2_k127_8683704_20 Thioredoxin - - - 0.000000000000000000000000000000000001123 153.0
HFD2_k127_8683704_21 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000005087 145.0
HFD2_k127_8683704_22 rhamnose metabolic process - - - 0.00000000000000000000000000000002076 130.0
HFD2_k127_8683704_23 Caspase domain - - - 0.000000000000000000000000000001148 129.0
HFD2_k127_8683704_24 TPR repeat - - - 0.000000000000000000000000000275 128.0
HFD2_k127_8683704_25 - - - - 0.0000000000004897 76.0
HFD2_k127_8683704_3 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000835 580.0
HFD2_k127_8683704_4 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 491.0
HFD2_k127_8683704_5 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009218 475.0
HFD2_k127_8683704_6 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004719 404.0
HFD2_k127_8683704_7 Protein of unknown function - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005372 401.0
HFD2_k127_8683704_8 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005179 361.0
HFD2_k127_8683704_9 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006815 369.0
HFD2_k127_8695666_0 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 610.0
HFD2_k127_8695666_1 Prephenate dehydrogenase K00210,K00220,K04517 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0047794,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12,1.3.1.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004235 467.0
HFD2_k127_8695666_10 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000005636 155.0
HFD2_k127_8695666_11 - - - - 0.00000000000000000000000000000000137 133.0
HFD2_k127_8695666_12 Protein of unknown function (DUF2442) - - - 0.00000000000000000000000000000002249 129.0
HFD2_k127_8695666_13 - - - - 0.0000000000000000000000000000866 121.0
HFD2_k127_8695666_14 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000002102 111.0
HFD2_k127_8695666_15 Uncharacterized protein conserved in bacteria (DUF2125) - - - 0.00000000000000000005593 102.0
HFD2_k127_8695666_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006382 413.0
HFD2_k127_8695666_3 Hydroxyacylglutathione hydrolase C-terminus K01069 GO:0003674,GO:0003824,GO:0004416,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0034641,GO:0043603,GO:0044237,GO:0051186,GO:0071704,GO:1901564 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004712 314.0
HFD2_k127_8695666_4 Redoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000361 261.0
HFD2_k127_8695666_5 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008121 252.0
HFD2_k127_8695666_6 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001643 241.0
HFD2_k127_8695666_7 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000003505 204.0
HFD2_k127_8695666_8 Pfam Methyltransferase - - - 0.00000000000000000000000000000000000000000003566 169.0
HFD2_k127_8695666_9 chorismate mutase - - - 0.000000000000000000000000000000000000000002456 169.0
HFD2_k127_8706127_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 533.0
HFD2_k127_8706127_1 Glycosyl transferase family 41 - - - 0.0000000000000000000000000000000000000000000000000000000000000000002192 243.0
HFD2_k127_8706127_2 Flavodoxin-like fold - - - 0.00000000000000000000000000000000009485 140.0
HFD2_k127_8706127_3 Flavodoxin-like fold - - - 0.0000000000000000000000000003997 115.0
HFD2_k127_8706127_4 Cytochrome c - - - 0.000000000000000000000000409 108.0
HFD2_k127_8708351_0 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000000000000001448 209.0
HFD2_k127_8708351_1 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000236 151.0
HFD2_k127_8708351_2 Sodium:sulfate symporter transmembrane region - - - 0.000000000000000000000000002127 128.0
HFD2_k127_8708351_3 FAD binding domain K05712 - 1.14.13.127 0.00001434 48.0
HFD2_k127_8710327_0 RNA polymerase sigma-54 factor K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004426 456.0
HFD2_k127_8710327_1 PFAM ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008974 329.0
HFD2_k127_8720482_0 Aminotransferase class-III K12256 - 2.6.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004952 557.0
HFD2_k127_8720482_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 519.0
HFD2_k127_8720482_10 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000000000002238 172.0
HFD2_k127_8720482_11 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000000000000000000000002896 163.0
HFD2_k127_8720482_12 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000001967 136.0
HFD2_k127_8720482_13 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000002883 139.0
HFD2_k127_8720482_14 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000000000000292 130.0
HFD2_k127_8720482_15 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000001146 129.0
HFD2_k127_8720482_16 COG3668 Plasmid stabilization system protein K19092 - - 0.000000000000000000000000000009146 121.0
HFD2_k127_8720482_17 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain K07746 - - 0.000000000000000000000004565 108.0
HFD2_k127_8720482_18 Rieske 2Fe-2S - - - 0.00000000000000000000003522 106.0
HFD2_k127_8720482_19 PIN domain - - - 0.000000000000000001209 90.0
HFD2_k127_8720482_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 465.0
HFD2_k127_8720482_20 Protein tyrosine serine phosphatase - - - 0.000000000000000002153 93.0
HFD2_k127_8720482_21 flagellar assembly - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000001084 89.0
HFD2_k127_8720482_22 Sel1-like repeats. - - - 0.00000000000000298 83.0
HFD2_k127_8720482_23 Domain of unknown function (DUF4919) - - - 0.0000000000001027 81.0
HFD2_k127_8720482_24 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.000000004491 63.0
HFD2_k127_8720482_25 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.00000006123 56.0
HFD2_k127_8720482_3 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008691 431.0
HFD2_k127_8720482_4 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 GO:0003674,GO:0003824,GO:0006072,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 341.0
HFD2_k127_8720482_5 Pfam Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008348 269.0
HFD2_k127_8720482_6 2OG-Fe(II) oxygenase superfamily K03919 - 1.14.11.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000002912 261.0
HFD2_k127_8720482_7 EVE domain - - - 0.000000000000000000000000000000000000000000000000000000000002312 212.0
HFD2_k127_8720482_8 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000000000004904 202.0
HFD2_k127_8720482_9 MOSC domain - - - 0.0000000000000000000000000000000000000000000008177 177.0
HFD2_k127_9179_0 Domain of unknown function (DUF3458_C) ARM repeats K01256 - 3.4.11.2 1.333e-295 932.0
HFD2_k127_9179_1 Binding-protein-dependent transport system inner membrane component K02011 - - 1.294e-195 625.0
HFD2_k127_9179_10 Domain of Unknown Function (DUF1259) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007827 374.0
HFD2_k127_9179_11 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007353 357.0
HFD2_k127_9179_12 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008147 344.0
HFD2_k127_9179_13 KR domain K03366 - 1.1.1.304,1.1.1.76 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 344.0
HFD2_k127_9179_14 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 352.0
HFD2_k127_9179_15 protein conserved in bacteria K21470 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 346.0
HFD2_k127_9179_16 TOBE domain K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023 302.0
HFD2_k127_9179_17 Pyruvate phosphate dikinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005409 283.0
HFD2_k127_9179_18 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001147 267.0
HFD2_k127_9179_19 PFAM peptidase M48 Ste24p - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001552 271.0
HFD2_k127_9179_2 Belongs to the AB hydrolase superfamily. MetX family K00641 - 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 522.0
HFD2_k127_9179_20 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005437 256.0
HFD2_k127_9179_21 Major facilitator Superfamily K08195 - - 0.00000000000000000000000000000000000000000000000000000000000000001112 241.0
HFD2_k127_9179_22 cytochrome - - - 0.00000000000000000000000000000000000000000000000000000000000000745 221.0
HFD2_k127_9179_23 - - - - 0.000000000000000000000000000000000000000000000000000000001424 216.0
HFD2_k127_9179_24 - - - - 0.000000000000000000000000000000000000000000000000000001537 199.0
HFD2_k127_9179_25 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000002917 194.0
HFD2_k127_9179_26 Bacterial protein of unknown function (DUF882) - - - 0.000000000000000000000000000000000000000000000000005778 187.0
HFD2_k127_9179_27 - - - - 0.000000000000000000000000000000000000000000002128 173.0
HFD2_k127_9179_28 Zincin-like metallopeptidase - - - 0.0000000000000000000000000000000002855 136.0
HFD2_k127_9179_29 Protein of Unknown function (DUF2784) - - - 0.0000000000000000000000000000001006 130.0
HFD2_k127_9179_3 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002818 508.0
HFD2_k127_9179_30 - - - - 0.00000000000000000024 96.0
HFD2_k127_9179_31 - - - - 0.000000000000000001517 97.0
HFD2_k127_9179_32 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000004046 78.0
HFD2_k127_9179_33 N-methylhydantoinase A acetone carboxylase, beta subunit K01473 - 3.5.2.14 0.00000000001337 76.0
HFD2_k127_9179_34 Domain of unknown function (DUF4142) K08995 - - 0.00000008066 61.0
HFD2_k127_9179_35 - - - - 0.0000002051 59.0
HFD2_k127_9179_37 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.0001162 54.0
HFD2_k127_9179_4 Peptide ABC transporter substrate-binding protein K15580 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008245 512.0
HFD2_k127_9179_5 Peptide ABC transporter substrate-binding protein K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007305 490.0
HFD2_k127_9179_6 Amidase K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006217 468.0
HFD2_k127_9179_7 associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 452.0
HFD2_k127_9179_8 COG0145 N-methylhydantoinase A acetone carboxylase, beta subunit K01473 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 444.0
HFD2_k127_9179_9 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004559 420.0
HFD2_k127_950886_0 TIGRFAM penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009775 578.0
HFD2_k127_950886_1 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000845 494.0
HFD2_k127_950886_10 Two component transcriptional regulator, winged helix family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009315 292.0
HFD2_k127_950886_11 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006964 273.0
HFD2_k127_950886_12 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002399 263.0
HFD2_k127_950886_13 Transposase IS200 like K07491 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001816 258.0
HFD2_k127_950886_14 Protein of unknown function DUF45 K07043 - - 0.00000000000000000000000000000000000000000000000000000000000000000005435 240.0
HFD2_k127_950886_15 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.00000000000000000000000000000000000000000000000000000003653 203.0
HFD2_k127_950886_16 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000505 194.0
HFD2_k127_950886_17 Cupin domain - - - 0.000000000000000000000000000000000000000000000219 171.0
HFD2_k127_950886_18 Domain of unknown function (DUF3576) - - - 0.00000000000000000000000000000000000000000005093 166.0
HFD2_k127_950886_19 COG1495 Disulfide bond formation protein DsbB K03611 - - 0.000000000000000000000000000000000000000003116 160.0
HFD2_k127_950886_2 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 424.0
HFD2_k127_950886_20 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.000000000000000000000000000000000001091 142.0
HFD2_k127_950886_21 TIGRFAM death-on-curing family protein K07341 - - 0.000000000000000000000000000000000009102 139.0
HFD2_k127_950886_22 transmembrane signaling receptor activity - - - 0.00000000000000000000000000000000002408 155.0
HFD2_k127_950886_23 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000001875 139.0
HFD2_k127_950886_24 Thiamine monophosphate synthase - - - 0.0000000000000000000000000000011 136.0
HFD2_k127_950886_25 - - - - 0.0000000000000000000000000009478 117.0
HFD2_k127_950886_26 MarR family - - - 0.000000000000000000000003564 109.0
HFD2_k127_950886_27 - - - - 0.000000000000000000006193 99.0
HFD2_k127_950886_28 Histidine Phosphotransfer domain - - - 0.000000000003173 72.0
HFD2_k127_950886_29 Addiction module antidote - - - 0.000000000003615 70.0
HFD2_k127_950886_3 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 405.0
HFD2_k127_950886_30 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane K08720 - - 0.000001201 61.0
HFD2_k127_950886_31 Adenylate cyclase - - - 0.00003602 48.0
HFD2_k127_950886_4 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 320.0
HFD2_k127_950886_5 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007135 310.0
HFD2_k127_950886_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 321.0
HFD2_k127_950886_7 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004597 324.0
HFD2_k127_950886_8 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004631 314.0
HFD2_k127_950886_9 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 302.0
HFD2_k127_962654_0 C-terminal, D2-small domain, of ClpB protein K03694 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 - 0.0 1184.0
HFD2_k127_962654_1 Oxidizes proline to glutamate for use as a carbon and nitrogen source K00249,K00294,K13821 - 1.2.1.88,1.3.8.7,1.5.5.2 0.0 1181.0
HFD2_k127_962654_10 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 285.0
HFD2_k127_962654_11 Belongs to the peptidase S11 family K01286 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001003 289.0
HFD2_k127_962654_12 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002017 276.0
HFD2_k127_962654_13 cytochrome K17230 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005931 273.0
HFD2_k127_962654_14 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002924 275.0
HFD2_k127_962654_15 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000007205 230.0
HFD2_k127_962654_16 Chaperone required for the assembly of the mitochondrial F1-ATPase - - - 0.000000000000000000000000000000000000000000000000000000004284 207.0
HFD2_k127_962654_17 Protein of unknown function (DUF1489) - - - 0.0000000000000000000000000000000000000000000000000102 184.0
HFD2_k127_962654_18 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000001455 176.0
HFD2_k127_962654_19 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.000000000000000000000000000000000000000000000002012 183.0
HFD2_k127_962654_2 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 532.0
HFD2_k127_962654_20 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000000000000000000000000002634 173.0
HFD2_k127_962654_21 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000003748 172.0
HFD2_k127_962654_22 Sirohaem biosynthesis protein central - - - 0.00000000000000000000000000000000000007523 148.0
HFD2_k127_962654_23 Domain of unknown function (DUF4328) - - - 0.00000000000000000000000000000000000007644 145.0
HFD2_k127_962654_24 Methyltransferase, FkbM family - - - 0.000000000000000000000000000001161 128.0
HFD2_k127_962654_25 phasin family - - - 0.000000000000000000000007615 108.0
HFD2_k127_962654_26 Type III flagellar switch regulator (C-ring) FliN C-term K02417 - - 0.00000000000000000000003422 102.0
HFD2_k127_962654_27 Methyltransferase, FkbM family - - - 0.00000000000000000000005003 108.0
HFD2_k127_962654_28 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.000000000000000002567 87.0
HFD2_k127_962654_29 Domain of unknown function (DUF4328) - - - 0.000000003651 59.0
HFD2_k127_962654_3 Peptidogalycan biosysnthesis/recognition K09919 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 454.0
HFD2_k127_962654_30 Protein conserved in bacteria - - - 0.00000002672 55.0
HFD2_k127_962654_31 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K17837 - 3.5.2.6 0.0000008862 55.0
HFD2_k127_962654_4 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 364.0
HFD2_k127_962654_5 Responsible for synthesis of pseudouridine from uracil K06179 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 355.0
HFD2_k127_962654_6 Domain of unknown function (DUF4010) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 323.0
HFD2_k127_962654_7 COG1192 ATPases involved in chromosome partitioning K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 305.0
HFD2_k127_962654_8 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 302.0
HFD2_k127_962654_9 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 301.0
HFD2_k127_977255_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1760.0
HFD2_k127_977255_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 6.91e-232 735.0
HFD2_k127_977255_10 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000005098 164.0
HFD2_k127_977255_11 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000007337 159.0
HFD2_k127_977255_13 Protein conserved in bacteria - - - 0.0000000000000000000000000000008696 130.0
HFD2_k127_977255_14 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0044424,GO:0044464,GO:0140096 2.3.2.6 0.0000000000000001033 83.0
HFD2_k127_977255_15 - - - - 0.0000000000000002101 83.0
HFD2_k127_977255_16 Response regulator receiver K03413 - - 0.00000000000003637 79.0
HFD2_k127_977255_17 - - - - 0.0000000003468 71.0
HFD2_k127_977255_2 Arginyl-tRNA synthetase K01887 - 6.1.1.19 9.335e-197 630.0
HFD2_k127_977255_3 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 588.0
HFD2_k127_977255_4 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003434 463.0
HFD2_k127_977255_5 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005679 443.0
HFD2_k127_977255_6 homoserine kinase activity K02204 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 425.0
HFD2_k127_977255_7 Glycine cleavage T-protein C-terminal barrel domain K00605 GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008483,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0016769,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0032991,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 421.0
HFD2_k127_977255_8 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000007594 218.0
HFD2_k127_977255_9 NADH ubiquinone oxidoreductase subunit NDUFA12 K00356 - 1.6.99.3 0.000000000000000000000000000000000000000000000008499 175.0