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Overview

ID MAG01655
Name HFD2_bin.47
Sample SMP0044
Taxonomy
Kingdom Bacteria
Phylum Chloroflexota
Class Limnocylindria
Order Limnocylindrales
Family CSP1-4
Genus JALYGJ01
Species
Assembly information
Completeness (%) 55.04
Contamination (%) 0.42
GC content (%) 69.0
N50 (bp) 9,790
Genome size (bp) 1,631,064

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1418

Gene name Description KEGG GOs EC E-value Score Sequence
HFD2_k127_1007486_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K09181 - - 0.0 1146.0
HFD2_k127_1007486_1 ABC-type multidrug transport system ATPase component K01990,K19340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009993 334.0
HFD2_k127_1007486_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000004566 230.0
HFD2_k127_1007486_3 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000003221 223.0
HFD2_k127_1007486_4 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000006193 182.0
HFD2_k127_1007486_5 NPCBM-associated, NEW3 domain of alpha-galactosidase - - - 0.000000000000000000000000000000000000000000000005033 189.0
HFD2_k127_1007486_6 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K07755 - 2.1.1.137 0.00000000000000000000000000000000001049 139.0
HFD2_k127_1007486_7 - - - - 0.00000000000000000000000001561 112.0
HFD2_k127_1007486_9 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.000000000000000000107 95.0
HFD2_k127_1025557_0 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 417.0
HFD2_k127_1025557_1 ATPases associated with a variety of cellular activities K09820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000184 266.0
HFD2_k127_1025557_2 Belongs to the bacterial solute-binding protein 9 family K09818 - - 0.000000000000000000000000000000000000000000000000000000000000663 225.0
HFD2_k127_1025557_3 ABC 3 transport family K09819 - - 0.00000000000000000000000000000000000000001334 171.0
HFD2_k127_1025557_4 Ferric uptake regulator family K03711 - - 0.000000000000000000000003094 108.0
HFD2_k127_1025557_5 PFAM isochorismatase hydrolase K08281 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006769,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0071704,GO:0072524,GO:1901360,GO:1901564 3.5.1.19 0.0000000005043 68.0
HFD2_k127_1231299_0 protein involved in exopolysaccharide biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 469.0
HFD2_k127_1231299_1 Oxidoreductase family, C-terminal alpha beta domain K13327 - 1.1.1.384 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009504 331.0
HFD2_k127_1231299_2 ROK family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 314.0
HFD2_k127_1231299_3 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001272 231.0
HFD2_k127_1262752_0 Aldehyde dehydrogenase family K00130 - 1.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 501.0
HFD2_k127_1262752_1 Fumarase C C-terminus K01744 - 4.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 494.0
HFD2_k127_1262752_2 PFAM Inosine uridine-preferring nucleoside hydrolase K01239 - 3.2.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008217 312.0
HFD2_k127_1262752_3 PFAM blue (type 1) copper domain protein - - - 0.000000000002909 80.0
HFD2_k127_1295798_0 glutaminyl-tRNA synthetase K01886 - 6.1.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 558.0
HFD2_k127_1295798_1 epoxide hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 531.0
HFD2_k127_1295798_2 LysM domain - - - 0.000000000000000000000000000000000000000000000000005098 187.0
HFD2_k127_1348131_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 4.47e-229 731.0
HFD2_k127_1348131_1 Peptidase dimerisation domain K01436,K01438,K01439 - 3.5.1.16,3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 495.0
HFD2_k127_1348131_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 292.0
HFD2_k127_1348131_3 Participates in initiation and elongation during chromosome replication K02314,K02316,K17680 - 3.6.4.12 0.000000000000000008471 93.0
HFD2_k127_1350412_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008091 463.0
HFD2_k127_1350412_1 Nickel-dependent hydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007217 451.0
HFD2_k127_1350412_2 NADH ubiquinone oxidoreductase, 20 Kd subunit K18007 - 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 310.0
HFD2_k127_1350412_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000664 236.0
HFD2_k127_1350412_4 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000133 209.0
HFD2_k127_1350412_5 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.000000000000000000000000000008758 121.0
HFD2_k127_1350412_6 AICARFT/IMPCHase bienzyme K00602 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.1.2.3,3.5.4.10 0.00000000006879 62.0
HFD2_k127_1350412_7 Malate dehydrogenase K00027 GO:0003674,GO:0003824,GO:0004470,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006090,GO:0006108,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016614,GO:0016615,GO:0019752,GO:0032787,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071704 1.1.1.38 0.00000002274 59.0
HFD2_k127_1350412_8 Hydrogenase maturation protease K03605 - - 0.00003895 53.0
HFD2_k127_1350412_9 TIGRFAM hydrogenase assembly chaperone hypC hupF K04653 - - 0.0003961 46.0
HFD2_k127_1369133_0 Nickel-dependent hydrogenase K06281 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005628 591.0
HFD2_k127_1369133_1 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000001165 217.0
HFD2_k127_1369133_2 TIGRFAM Ni Fe-hydrogenase, b-type cytochrome subunit K03620 - - 0.00000000000000000000000000000000000000000000001243 181.0
HFD2_k127_1369133_4 Stage II sporulation protein E (SpoIIE) - - - 0.00000000000003356 86.0
HFD2_k127_1369133_5 Cytochrome c7 and related cytochrome c - - - 0.00000003129 66.0
HFD2_k127_1404953_0 Type II/IV secretion system protein K02283 - - 5.504e-199 629.0
HFD2_k127_1404953_1 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000823 452.0
HFD2_k127_1404953_10 regulatory protein, arsR - - - 0.0000000000000000000000000000000458 135.0
HFD2_k127_1404953_11 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000000000000000000001638 131.0
HFD2_k127_1404953_12 PHP-associated - - - 0.00000000000000000000000000001411 127.0
HFD2_k127_1404953_13 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.00000000000000000000000001852 109.0
HFD2_k127_1404953_14 Uncharacterized ACR, COG1430 K09005 - - 0.000000000003386 74.0
HFD2_k127_1404953_15 Glycosyltransferase family 87 - - - 0.0000327 56.0
HFD2_k127_1404953_16 Flp/Fap pilin component K02651 - - 0.0003039 45.0
HFD2_k127_1404953_17 Helix-turn-helix domain - GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0005955 49.0
HFD2_k127_1404953_2 Belongs to the EPSP synthase family. MurA subfamily K00790 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006875 338.0
HFD2_k127_1404953_3 NUBPL iron-transfer P-loop NTPase K02282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003578 329.0
HFD2_k127_1404953_4 Type II secretion system (T2SS), protein F K12511 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001147 255.0
HFD2_k127_1404953_5 Type II secretion system K12510 - - 0.00000000000000000000000000000000000000000000000000000000000009449 225.0
HFD2_k127_1404953_6 PFAM conserved K07027 - - 0.00000000000000000000000000000000000000000000000000000000001338 225.0
HFD2_k127_1404953_7 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000001438 198.0
HFD2_k127_1404953_8 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.00000000000000000000000000000000000000001103 157.0
HFD2_k127_1404953_9 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000002811 134.0
HFD2_k127_1421592_0 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 605.0
HFD2_k127_1421592_1 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 581.0
HFD2_k127_1421592_10 Belongs to the UPF0173 family - - - 0.0000000000000000000000000000000000000000000000000000000002244 214.0
HFD2_k127_1421592_11 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000376 210.0
HFD2_k127_1421592_12 AMP-binding enzyme - - - 0.000000000000000000000000000000000000000002984 175.0
HFD2_k127_1421592_13 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000831 155.0
HFD2_k127_1421592_14 SPFH Band 7 PHB domain protein - - - 0.00000000000000000000005808 111.0
HFD2_k127_1421592_15 UbiA prenyltransferase family - - - 0.000000000000000000007749 103.0
HFD2_k127_1421592_16 dolichyl monophosphate biosynthetic process K00981,K18678 - 2.7.1.182,2.7.7.41 0.000000000000000006218 94.0
HFD2_k127_1421592_17 acetyltransferase - - - 0.0000001141 63.0
HFD2_k127_1421592_18 Hint domain - - - 0.000002842 56.0
HFD2_k127_1421592_19 Pfam:DUF385 - - - 0.00006702 52.0
HFD2_k127_1421592_2 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009295 413.0
HFD2_k127_1421592_3 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005172 421.0
HFD2_k127_1421592_4 Polysaccharide biosynthesis protein K03328 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 367.0
HFD2_k127_1421592_5 PEP-utilising enzyme, mobile domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 362.0
HFD2_k127_1421592_6 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 316.0
HFD2_k127_1421592_7 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003681 278.0
HFD2_k127_1421592_8 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000777 233.0
HFD2_k127_1421592_9 Protein of unknown function (DUF3419) K13622 - - 0.000000000000000000000000000000000000000000000000000000000000008839 232.0
HFD2_k127_1504098_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 GO:0000731,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0018130,GO:0019438,GO:0019985,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042276,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000558 344.0
HFD2_k127_1504098_1 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000195 258.0
HFD2_k127_1504098_2 Protein of unknown function DUF45 K07043 - - 0.0000000000000000000000000000000000002136 151.0
HFD2_k127_1504098_3 - - - - 0.0000000000000000000000000000000007714 143.0
HFD2_k127_1504098_4 Allophanate hydrolase subunit 2 K06350 - - 0.0000000000000000000000000004044 115.0
HFD2_k127_1504098_5 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000002902 115.0
HFD2_k127_1504098_6 Peptidase family M23 - - - 0.0000000000000000000007761 107.0
HFD2_k127_1504098_7 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000001855 73.0
HFD2_k127_1509705_0 Belongs to the formate--tetrahydrofolate ligase family K01938 GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.3 3.956e-204 652.0
HFD2_k127_1509705_1 Histidine ammonia-lyase K01745 - 4.3.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004974 492.0
HFD2_k127_1509705_10 Phosphoglycerate mutase - - - 0.000000000000000000000000000000001473 141.0
HFD2_k127_1509705_11 binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000001179 130.0
HFD2_k127_1509705_12 Formiminotransferase-cyclodeaminase K01746 - 4.3.1.4 0.0000000000000000000000000729 115.0
HFD2_k127_1509705_13 ACT domain protein - - - 0.0000000005131 65.0
HFD2_k127_1509705_14 acetyltransferase - - - 0.000001558 58.0
HFD2_k127_1509705_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005268 340.0
HFD2_k127_1509705_3 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 325.0
HFD2_k127_1509705_4 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000005356 270.0
HFD2_k127_1509705_5 serine-type endopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008135 268.0
HFD2_k127_1509705_6 PFAM ABC transporter K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003745 250.0
HFD2_k127_1509705_7 PFAM binding-protein-dependent transport systems inner membrane component K02050 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000001776 221.0
HFD2_k127_1509705_8 NMT1/THI5 like K02051 - - 0.0000000000000000000000000000000000000000000000000000000001293 225.0
HFD2_k127_1509705_9 YbaK prolyl-tRNA synthetase associated region - - - 0.0000000000000000000000000000000000000000000009594 171.0
HFD2_k127_1721950_0 Belongs to the proline racemase family K01777,K12658 - 5.1.1.4,5.1.1.8 0.00000000000000000000000000000000000000000000000000000000000000003812 232.0
HFD2_k127_1721950_1 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 0.0000000000000000000000000000000000000000000002327 178.0
HFD2_k127_1721950_2 Proline racemase K01777 - 5.1.1.4 0.0000004302 60.0
HFD2_k127_1781494_0 Glycosyl hydrolases family 43 K06113 - 3.2.1.99 3.771e-215 685.0
HFD2_k127_1781494_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006763 257.0
HFD2_k127_1781494_10 Periplasmic copper-binding protein (NosD) - - - 0.000006134 60.0
HFD2_k127_1781494_11 - - - - 0.0002356 43.0
HFD2_k127_1781494_12 ABC-2 family transporter protein K01992 - - 0.0006882 51.0
HFD2_k127_1781494_2 BioY family K03523 - - 0.00000000000000000000000000000000000000000008929 167.0
HFD2_k127_1781494_3 META domain K03668 - - 0.000000000000000000000000000000000000000000824 167.0
HFD2_k127_1781494_4 Beta-lactamase - - - 0.000000000000000000000000000007023 130.0
HFD2_k127_1781494_5 Protein of unknown function (DUF541) K09807 - - 0.000000000000000000000000008103 120.0
HFD2_k127_1781494_6 - - - - 0.0000000000000000000005689 108.0
HFD2_k127_1781494_7 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.00000001305 58.0
HFD2_k127_1781494_8 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.00000001345 63.0
HFD2_k127_1781494_9 hydroxymethylglutaryl-CoA reductase (NADPH) activity - - - 0.0000003604 57.0
HFD2_k127_182102_0 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 346.0
HFD2_k127_182102_1 glycosyl transferase family 2 K21349 - 2.4.1.268 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 317.0
HFD2_k127_182102_2 Probable RNA and SrmB- binding site of polymerase A K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006919 330.0
HFD2_k127_182102_3 PFAM HNH endonuclease - - - 0.000000000000000000000000000000000008047 144.0
HFD2_k127_182102_4 Acetyltransferase (GNAT) family - - - 0.000000000000002245 88.0
HFD2_k127_182102_5 dna ligase - - - 0.00000734 56.0
HFD2_k127_1836698_0 Beta-eliminating lyase K01667 - 4.1.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006958 584.0
HFD2_k127_1836698_1 Cys/Met metabolism PLP-dependent enzyme K01739,K01758,K01760,K01761 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 382.0
HFD2_k127_1836698_2 Exporter of polyketide antibiotics K01992 - - 0.000000000000000000000000000000000000000004704 162.0
HFD2_k127_1836698_3 Sigma-70, region 4 K03088 - - 0.00000000000000000000000001117 116.0
HFD2_k127_1890190_0 ABC-type sugar transport system, ATPase component K10441 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004587 617.0
HFD2_k127_1890190_1 AP endonuclease family 2 C terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007755 468.0
HFD2_k127_1890190_10 Alpha beta hydrolase - - - 0.00000000000000000000003736 102.0
HFD2_k127_1890190_11 metallopeptidase activity - - - 0.000000000005602 77.0
HFD2_k127_1890190_2 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 335.0
HFD2_k127_1890190_3 protein containing SIS (Sugar isomerase) phosphosugar binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006966 300.0
HFD2_k127_1890190_4 Periplasmic binding protein domain K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001985 292.0
HFD2_k127_1890190_5 Branched-chain amino acid transport system / permease component K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002551 292.0
HFD2_k127_1890190_6 DeoC/LacD family aldolase K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002725 286.0
HFD2_k127_1890190_7 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000002093 235.0
HFD2_k127_1890190_8 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.0000000000000000000000000000000000000000000000000000000000003802 231.0
HFD2_k127_1890190_9 dehydrogenases and related proteins - - - 0.0000000000000000000000000000001864 127.0
HFD2_k127_1896170_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000396 385.0
HFD2_k127_1896170_1 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004721 349.0
HFD2_k127_1896170_10 - - - - 0.00000000000005111 81.0
HFD2_k127_1896170_11 - - - - 0.00000000001693 70.0
HFD2_k127_1896170_2 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007754 327.0
HFD2_k127_1896170_3 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001486 256.0
HFD2_k127_1896170_4 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000001791 231.0
HFD2_k127_1896170_5 PFAM AMP-dependent synthetase and ligase - - - 0.000000000000000000000000000000000000000000000000000003787 217.0
HFD2_k127_1896170_6 Transcriptional regulator - - - 0.00000000000000000000000000000000000000003597 162.0
HFD2_k127_1896170_7 translation initiation factor activity - - - 0.00000000000000000000000000000000001324 156.0
HFD2_k127_1896170_8 ABC-2 family transporter protein - - - 0.0000000000000000000000000001132 130.0
HFD2_k127_1896170_9 Alpha/beta hydrolase family - - - 0.00000000000000000002565 104.0
HFD2_k127_1903414_0 Alpha amylase, catalytic domain - - - 0.0 1054.0
HFD2_k127_1903414_1 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007579 316.0
HFD2_k127_1903414_2 Belongs to the NiCoT transporter (TC 2.A.52) family K07241 - - 0.000000000000000000000000000000000000000000000000000000000000003662 228.0
HFD2_k127_1903414_3 Oxidoreductase molybdopterin binding domain - - - 0.000000008654 65.0
HFD2_k127_191723_0 Belongs to the ClpA ClpB family K03696 - - 0.0 1017.0
HFD2_k127_191723_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005727 422.0
HFD2_k127_191723_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000876 257.0
HFD2_k127_191723_3 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000007282 209.0
HFD2_k127_2007202_0 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000006905 236.0
HFD2_k127_2007202_1 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000003103 157.0
HFD2_k127_2007202_2 Glycosyl transferase K00728 - 2.4.1.109 0.00000000000000000000000000000000001296 157.0
HFD2_k127_2007202_3 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000006555 113.0
HFD2_k127_2013012_0 haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED - - - 1.359e-281 896.0
HFD2_k127_2013012_1 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008445 390.0
HFD2_k127_2013012_2 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000006279 235.0
HFD2_k127_2013012_3 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000001394 154.0
HFD2_k127_2013012_4 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000001094 115.0
HFD2_k127_2013012_5 PFAM CBS domain K07182 - - 0.0000000000000000000007263 103.0
HFD2_k127_2038632_0 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006226 493.0
HFD2_k127_2038632_1 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 401.0
HFD2_k127_2038632_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000001023 217.0
HFD2_k127_2038632_3 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000000000006098 196.0
HFD2_k127_2038632_4 Mur ligase family, catalytic domain K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000002297 194.0
HFD2_k127_2038632_5 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000001339 113.0
HFD2_k127_2038632_6 SnoaL-like domain - - - 0.0000000009595 64.0
HFD2_k127_2055048_0 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 1.282e-203 648.0
HFD2_k127_2055048_1 succinate dehydrogenase, flavoprotein subunit K00239 GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0043436,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071704,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0072350,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 4.365e-195 625.0
HFD2_k127_2055048_10 Carbamoyl-phosphate synthetase large chain domain protein K01961,K01968,K11263 - 6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4 0.000000005269 61.0
HFD2_k127_2055048_2 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 479.0
HFD2_k127_2055048_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 367.0
HFD2_k127_2055048_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005213 347.0
HFD2_k127_2055048_5 Glyoxalase-like domain K05606 - 5.1.99.1 0.00000000000000000000000000000005876 132.0
HFD2_k127_2055048_6 TIGRFAM Succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.00000000000000000000000003176 115.0
HFD2_k127_2055048_7 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.0000000000000000192 91.0
HFD2_k127_2055048_8 - - - - 0.000000000332 72.0
HFD2_k127_2055048_9 Biotin carboxylase C-terminal domain K11263 - 6.3.4.14,6.4.1.2,6.4.1.3 0.0000000004742 69.0
HFD2_k127_2134719_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 368.0
HFD2_k127_2134719_1 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003485 380.0
HFD2_k127_2134719_2 PFAM Glutamine cyclotransferase K00683 - 2.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000001543 233.0
HFD2_k127_2134719_3 Psort location Cytoplasmic, score - - - 0.0000000000000000000000004558 110.0
HFD2_k127_2134719_4 Putative adhesin - - - 0.00000000006855 74.0
HFD2_k127_2134719_5 - - - - 0.0000001618 57.0
HFD2_k127_2166195_0 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 304.0
HFD2_k127_2166195_1 pfam abc K02028 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004183 292.0
HFD2_k127_2166195_10 NYN domain - - - 0.0000000000000000000000000000000001275 152.0
HFD2_k127_2166195_11 Acylphosphatase K01512 - 3.6.1.7 0.000000000000000000002403 96.0
HFD2_k127_2166195_12 - catabolite gene activator and regulatory subunit of cAMP-dependent protein - - - 0.000000000000000002208 94.0
HFD2_k127_2166195_13 ABC transporter K02003 - - 0.00000000000000001592 88.0
HFD2_k127_2166195_14 ABC transporter, permease protein K02029,K02030,K09971,K17062 - - 0.00000372 50.0
HFD2_k127_2166195_15 Acetyltransferase (GNAT) domain K09994 - - 0.00005038 53.0
HFD2_k127_2166195_2 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001421 284.0
HFD2_k127_2166195_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001782 286.0
HFD2_k127_2166195_4 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008171 274.0
HFD2_k127_2166195_5 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005654 265.0
HFD2_k127_2166195_6 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000006982 251.0
HFD2_k127_2166195_7 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain K21023 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000003654 204.0
HFD2_k127_2166195_8 L-lysine 6-monooxygenase (NADPH-requiring) - - - 0.000000000000000000000000000000000000000000003153 185.0
HFD2_k127_2166195_9 DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.000000000000000000000000000000000000000004086 169.0
HFD2_k127_2275282_0 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000396 419.0
HFD2_k127_2275282_1 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 332.0
HFD2_k127_2275282_2 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005798 304.0
HFD2_k127_2275282_3 Barrel-sandwich domain of CusB or HlyD membrane-fusion K01993 - - 0.00000000000000000000000000000000000000643 165.0
HFD2_k127_2275282_4 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000001232 145.0
HFD2_k127_2275282_5 Tellurite resistance protein TerB - - - 0.00000000000000000000000000000000003242 144.0
HFD2_k127_2275282_6 Sodium Bile acid symporter family K03325,K03741 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015104,GO:0015105,GO:0015291,GO:0015297,GO:0015318,GO:0015698,GO:0015699,GO:0015700,GO:0016020,GO:0022804,GO:0022857,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656 1.20.4.1 0.00000000000000000000000008308 108.0
HFD2_k127_229065_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004799 299.0
HFD2_k127_229065_1 ribonuclease activity - - - 0.0000000000000000000000000000000000000000000000000000007315 196.0
HFD2_k127_229065_2 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000000000007388 139.0
HFD2_k127_229065_3 SpoVT / AbrB like domain - - - 0.00000000000000001297 84.0
HFD2_k127_229065_4 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.000000000000001142 80.0
HFD2_k127_2399782_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 612.0
HFD2_k127_2399782_1 threonyl-tRNA aminoacylation K01881 - 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000722 561.0
HFD2_k127_2399782_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005487 565.0
HFD2_k127_2399782_3 Mo-co oxidoreductase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004742 476.0
HFD2_k127_2399782_4 PFAM regulatory protein LuxR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005015 351.0
HFD2_k127_2399782_5 Protein of unknown function (DUF4242) - - - 0.00000000000000000000000000002454 119.0
HFD2_k127_2399782_6 Methyl-transferase - - - 0.00000000000000000000000006805 117.0
HFD2_k127_2405942_0 FeS assembly protein SufB K09014 - - 8.837e-206 649.0
HFD2_k127_2405942_1 Belongs to the citrate synthase family K01647 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005217 593.0
HFD2_k127_2405942_10 FeS assembly protein SufD K09014,K09015 - - 0.00000000000000000000000000000000000000000000000000001237 207.0
HFD2_k127_2405942_11 Acetyltransferase (GNAT) domain - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006104,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 - 0.0000000000000000000000000000000000000000000000005503 190.0
HFD2_k127_2405942_12 Ornithine cyclodeaminase mu-crystallin family K01750,K19244 - 1.4.1.1,4.3.1.12 0.00000000000000000000000000000000000000001608 166.0
HFD2_k127_2405942_13 nitrite reductase [NAD(P)H] activity K05710 - - 0.0000000000000000002604 92.0
HFD2_k127_2405942_14 Cupin 2, conserved barrel domain protein - - - 0.0000000000000001013 83.0
HFD2_k127_2405942_15 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000003148 69.0
HFD2_k127_2405942_16 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000295 61.0
HFD2_k127_2405942_2 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 592.0
HFD2_k127_2405942_3 transport system, permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004601 370.0
HFD2_k127_2405942_4 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004705 325.0
HFD2_k127_2405942_5 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 313.0
HFD2_k127_2405942_6 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 300.0
HFD2_k127_2405942_7 N-acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003934 275.0
HFD2_k127_2405942_8 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000725 211.0
HFD2_k127_2405942_9 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000008769 205.0
HFD2_k127_2418361_0 Alpha amylase, catalytic domain - - - 0.0 1079.0
HFD2_k127_2418361_1 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005088 404.0
HFD2_k127_2418361_2 PFAM oxidoreductase molybdopterin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008251 399.0
HFD2_k127_2418361_3 PFAM Glucose Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 330.0
HFD2_k127_2418361_4 Glucose sorbosone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006013 320.0
HFD2_k127_2418361_5 Belongs to the NiCoT transporter (TC 2.A.52) family K07241 - - 0.0000000000000000000000000000000000000000000000000000000000000008264 230.0
HFD2_k127_2418361_6 Domain of unknown function (DUF4111) K00984 - 2.7.7.47 0.000000000000000000000000000000000000000000000002062 180.0
HFD2_k127_2486441_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 1.891e-278 886.0
HFD2_k127_2486441_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 374.0
HFD2_k127_2486441_2 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003392 264.0
HFD2_k127_2486441_3 Belongs to the peptidase S41A family K03797 GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016787,GO:0019538,GO:0023052,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000003997 238.0
HFD2_k127_2486441_4 Tyrosine phosphatase family K01104 - 3.1.3.48 0.00000000000000000000000000000000002539 152.0
HFD2_k127_2513518_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 437.0
HFD2_k127_2513518_1 CarboxypepD_reg-like domain K13276 - - 0.00000006352 66.0
HFD2_k127_2528943_0 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 336.0
HFD2_k127_2528943_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001992 314.0
HFD2_k127_2528943_10 PFAM glycoside hydrolase family 25 K07273 - - 0.00000000000000000000000000000000000003703 154.0
HFD2_k127_2528943_11 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000002268 128.0
HFD2_k127_2528943_12 phosphoglycerate mutase K02226,K22316 GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 3.1.26.4,3.1.3.73 0.0000000000000000000000001045 122.0
HFD2_k127_2528943_13 - - - - 0.00000000000000000002733 100.0
HFD2_k127_2528943_14 pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000000004616 101.0
HFD2_k127_2528943_2 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006032 312.0
HFD2_k127_2528943_3 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000001154 265.0
HFD2_k127_2528943_4 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000939 262.0
HFD2_k127_2528943_5 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000002947 223.0
HFD2_k127_2528943_6 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000004586 233.0
HFD2_k127_2528943_7 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000002432 209.0
HFD2_k127_2528943_8 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000002713 199.0
HFD2_k127_2528943_9 PFAM glycoside hydrolase family 25 K07273 - - 0.00000000000000000000000000000000000001351 157.0
HFD2_k127_2536675_0 aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 322.0
HFD2_k127_2536675_1 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001306 273.0
HFD2_k127_2536675_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.00000000000000000000000000000000005519 147.0
HFD2_k127_2536675_3 Capsule synthesis protein, CapA K07282 - - 0.0000000000000000000000000000001799 139.0
HFD2_k127_2536675_4 TIGRFAM phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000002462 126.0
HFD2_k127_2603584_0 Cell division protein FtsA K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 439.0
HFD2_k127_2603584_1 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000001082 185.0
HFD2_k127_2603584_2 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000008654 88.0
HFD2_k127_2603584_3 Stage II sporulation protein K21449 - - 0.00000000000000003893 95.0
HFD2_k127_2603584_4 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000009461 94.0
HFD2_k127_2603584_5 Lysin motif - - - 0.000000244 60.0
HFD2_k127_2603584_6 PFAM Glycosyl transferases group 1 - - - 0.0002331 52.0
HFD2_k127_2617843_0 Aminotransferase class-III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003326 550.0
HFD2_k127_2617843_1 Bacterial transcriptional activator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009814 552.0
HFD2_k127_2617843_2 Calcineurin-like phosphoesterase K01077 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 353.0
HFD2_k127_2617843_3 NlpC/P60 family K19224 - - 0.00000000000003674 84.0
HFD2_k127_262598_0 Aldehyde dehydrogenase family - - - 2.37e-197 625.0
HFD2_k127_262598_1 Bacterial protein of unknown function (DUF853) K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 519.0
HFD2_k127_262598_10 Amidohydrolase family K01465 - 3.5.2.3 0.00000000000000000000000000000004938 132.0
HFD2_k127_262598_11 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000001856 112.0
HFD2_k127_262598_12 Pyridoxamine 5'-phosphate oxidase - - - 0.000000000000000000000001728 108.0
HFD2_k127_262598_13 COG0044 Dihydroorotase and related cyclic amidohydrolases K01465 - 3.5.2.3 0.00000000000000000006566 92.0
HFD2_k127_262598_14 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000004275 60.0
HFD2_k127_262598_2 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 484.0
HFD2_k127_262598_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458,K14660 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008455 386.0
HFD2_k127_262598_4 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009025 314.0
HFD2_k127_262598_5 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000001705 250.0
HFD2_k127_262598_6 Acyl transferase domain K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000002452 253.0
HFD2_k127_262598_7 Winged helix DNA-binding domain K09927 - - 0.000000000000000000000000000000000000000000000000000000000000000001425 241.0
HFD2_k127_262598_8 Diguanylate cyclase K03320 - - 0.000000000000000000000000000000000000000000000000009965 201.0
HFD2_k127_262598_9 Colicin V production protein - - - 0.00000000000000000000000000000000000000000003484 179.0
HFD2_k127_2651448_0 E1-E2 ATPase K01533 - 3.6.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009266 422.0
HFD2_k127_2651448_1 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000787 195.0
HFD2_k127_2651448_2 higher expression in the presence of deoxycholate inhibits cell growth completely. Bile acid detergents such as deoxycholate are important for host defense against bacterial growth in the gall bladder and duodenum K02035 GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0006869,GO:0008150,GO:0010876,GO:0015711,GO:0015718,GO:0015721,GO:0015849,GO:0015850,GO:0030288,GO:0030313,GO:0031975,GO:0033036,GO:0042597,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0071702 - 0.000000000000000000000000000000000000000000000001627 194.0
HFD2_k127_2651448_3 PFAM Asparaginase glutaminase K01424 - 3.5.1.1 0.00000000000000000000000000000000000000000000001517 183.0
HFD2_k127_2651448_4 Peptidase MA superfamily - - - 0.00000000000000000000000000000009928 141.0
HFD2_k127_2651448_5 Bacterial protein of unknown function (DUF951) - - - 0.00000000000000000007956 90.0
HFD2_k127_2651448_6 metal-dependent hydrolase with the TIM-barrel fold - - - 0.00000000000004067 85.0
HFD2_k127_2694569_0 hydrolase activity, acting on ester bonds K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 506.0
HFD2_k127_2694569_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 385.0
HFD2_k127_2694569_2 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000003511 235.0
HFD2_k127_2694569_3 PFAM helix-turn-helix HxlR type - - - 0.000000000000000000000000000000001566 135.0
HFD2_k127_2694569_4 L-valine transmembrane transporter activity - - - 0.000001505 60.0
HFD2_k127_2713052_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 447.0
HFD2_k127_2713052_1 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006246 299.0
HFD2_k127_2713052_2 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004383 263.0
HFD2_k127_2713052_3 AAA ATPase domain - - - 0.00000000000000000000000000000000000000000000000000000000000001104 228.0
HFD2_k127_2713052_4 metalloendopeptidase activity K03799 - - 0.0000000000000000000000000000000000000000000000001145 192.0
HFD2_k127_2713052_5 Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000000000000000000000003048 159.0
HFD2_k127_2713052_6 Sigma-70 region 2 K03088 - - 0.000000000004727 74.0
HFD2_k127_2717673_0 PDZ domain (Also known as DHR or GLGF) - - - 0.0000000000000000000000000000000000000000000000000000000000000003863 235.0
HFD2_k127_2717673_1 response regulator receiver K07658,K07668 - - 0.000000000000000000000000000000000000000000000000000000000003652 216.0
HFD2_k127_2717673_2 PFAM ATP-binding region, ATPase domain protein K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000001584 196.0
HFD2_k127_2717673_3 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000001492 140.0
HFD2_k127_2717673_4 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000000000006449 98.0
HFD2_k127_2758325_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004194 338.0
HFD2_k127_2758325_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 330.0
HFD2_k127_2758325_2 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000001055 231.0
HFD2_k127_2758325_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 0.000000002263 64.0
HFD2_k127_2780602_0 Methionine synthase K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.0 1504.0
HFD2_k127_2780602_1 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005505 290.0
HFD2_k127_2780602_2 Methyltransferase domain K07003 - - 0.000000000000000000000000000000002997 139.0
HFD2_k127_2780602_3 - - - - 0.000000000000006868 78.0
HFD2_k127_289239_0 TIGRFAM F420-dependent oxidoreductase, G6PDH family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004879 511.0
HFD2_k127_289239_1 COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 317.0
HFD2_k127_289239_2 Uncharacterised protein family UPF0052 K11212 - 2.7.8.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 314.0
HFD2_k127_289239_3 epimerase K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000002564 272.0
HFD2_k127_289239_4 F420-0:Gamma-glutamyl ligase K12234 GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0044237,GO:0044249,GO:0044464,GO:0051186,GO:0051188,GO:0071944 6.3.2.31,6.3.2.34 0.00000000000000000000000000000000000000000000000000000000000000000000000007957 256.0
HFD2_k127_289239_5 Protein of unknown function (DUF1684) K09164 - - 0.000000000000000000000000000000000000000000000000003293 186.0
HFD2_k127_289239_6 pyridoxamine 5'-phosphate K07005 - - 0.00000000000000000000001266 110.0
HFD2_k127_289239_7 2-phospho-L-lactate guanylyltransferase K14941 - 2.7.7.68 0.00000000000000000003622 99.0
HFD2_k127_3010080_0 - - - - 0.000000000000000000000000000000000000000000000000008141 187.0
HFD2_k127_3010080_1 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000002433 189.0
HFD2_k127_3010080_2 PFAM Rhomboid family protein K19225 - 3.4.21.105 0.0000000000000000000000000002516 128.0
HFD2_k127_3010080_3 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 0.00000000000000000000000001329 117.0
HFD2_k127_3010080_4 Involved in the TonB-independent uptake of proteins K03641 - - 0.0000000006332 72.0
HFD2_k127_3010080_5 belongs to the sigma-70 factor family, ECF subfamily - - - 0.000001007 57.0
HFD2_k127_302034_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944 1.2.7.11,1.2.7.3 1.043e-248 783.0
HFD2_k127_302034_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 2.773e-204 658.0
HFD2_k127_302034_10 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002727 278.0
HFD2_k127_302034_11 dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006315 255.0
HFD2_k127_302034_12 phosphoribosyltransferase K07100 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004062 246.0
HFD2_k127_302034_13 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001275 241.0
HFD2_k127_302034_15 Putative neutral zinc metallopeptidase K06973 - - 0.0000000000000000000000000000000000000000000000007122 183.0
HFD2_k127_302034_16 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.000000000000000000000000000000000000000000151 171.0
HFD2_k127_302034_17 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease - - - 0.000000000000000000000000000000000000000001498 162.0
HFD2_k127_302034_18 PFAM luciferase-like - - - 0.00000000000000000000000000000000000001507 162.0
HFD2_k127_302034_19 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.0000000000000000000000000002905 128.0
HFD2_k127_302034_2 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 546.0
HFD2_k127_302034_20 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000224 111.0
HFD2_k127_302034_21 CBS domain - - - 0.0000000000000000001564 95.0
HFD2_k127_302034_23 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.000000000612 63.0
HFD2_k127_302034_25 CsbD-like - - - 0.0002478 46.0
HFD2_k127_302034_26 PFAM GCN5-related N-acetyltransferase - - - 0.0004233 52.0
HFD2_k127_302034_3 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006047 471.0
HFD2_k127_302034_4 Sodium:sulfate symporter transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 486.0
HFD2_k127_302034_5 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 454.0
HFD2_k127_302034_6 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 379.0
HFD2_k127_302034_7 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 326.0
HFD2_k127_302034_8 Starch synthase catalytic domain K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005213 331.0
HFD2_k127_302034_9 Putative esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 316.0
HFD2_k127_3061350_0 protein involved in exopolysaccharide biosynthesis - - - 3.757e-218 706.0
HFD2_k127_3061350_1 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005688 337.0
HFD2_k127_3061350_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 332.0
HFD2_k127_3061350_3 ROK family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004408 295.0
HFD2_k127_3061350_4 Periplasmic binding protein domain K10543 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005975,GO:0005996,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0015749,GO:0015750,GO:0015753,GO:0019321,GO:0030246,GO:0030288,GO:0030313,GO:0031975,GO:0034219,GO:0036094,GO:0042597,GO:0042732,GO:0044238,GO:0044281,GO:0044464,GO:0048029,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704 - 0.0000000000000000000000000000000000000000000000000000000000000000001966 241.0
HFD2_k127_3061350_5 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000001137 229.0
HFD2_k127_3087301_0 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006303 500.0
HFD2_k127_3087301_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000002255 225.0
HFD2_k127_3087301_2 Universal stress protein family - - - 0.0000000000000000000000007452 111.0
HFD2_k127_3087301_3 PFAM TrkA-N domain K03499 - - 0.00000007376 56.0
HFD2_k127_3087301_4 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.0006973 45.0
HFD2_k127_308876_0 von Willebrand factor (vWF) type D domain - - - 0.000000000000000000000000000003124 140.0
HFD2_k127_3109407_0 ABC transporter K06147 - - 4.7e-244 775.0
HFD2_k127_3109407_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 515.0
HFD2_k127_3109407_2 spermidine synthase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 447.0
HFD2_k127_3109407_3 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 327.0
HFD2_k127_3109407_4 PFAM isochorismatase hydrolase K08281 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006769,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0071704,GO:0072524,GO:1901360,GO:1901564 3.5.1.19 0.000000000000000000000000000000000000000000000000000000000000007847 220.0
HFD2_k127_3109407_5 Lysyl oxidase - - - 0.00000000000000000000000000000000002833 146.0
HFD2_k127_3109407_6 Sulfotransferase domain - - - 0.000000000000000000001255 106.0
HFD2_k127_316694_0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 527.0
HFD2_k127_316694_1 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000005734 195.0
HFD2_k127_316694_2 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000002496 131.0
HFD2_k127_316694_3 Helix-turn-helix domain - - - 0.000000000002034 72.0
HFD2_k127_316694_4 Transglycosylase associated protein - - - 0.000000000003827 70.0
HFD2_k127_316694_5 integral membrane protein - - - 0.0000754 52.0
HFD2_k127_3177654_0 Two component transcriptional regulator, LuxR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001796 258.0
HFD2_k127_3177654_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07777 - 2.7.13.3 0.000000000000000000000000000006194 139.0
HFD2_k127_3177654_3 histidine kinase, dimerisation and phosphoacceptor region K07777 - 2.7.13.3 0.00000000000000000000000004213 121.0
HFD2_k127_3177654_4 Flp Fap pilin component K02651 - - 0.00001734 49.0
HFD2_k127_3177654_5 Flp Fap pilin component K02651 - - 0.0006809 48.0
HFD2_k127_3188647_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 524.0
HFD2_k127_3188647_1 Aminotransferase K00812,K10907 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 469.0
HFD2_k127_3188647_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 449.0
HFD2_k127_3188647_3 Dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000004517 188.0
HFD2_k127_3188647_4 PFAM basic membrane lipoprotein K07335 - - 0.0000000000000000000000000000000000000000001797 174.0
HFD2_k127_3188647_5 CoA binding domain K01740,K06929 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.5.1.49 0.0000000000000000000000000000000237 137.0
HFD2_k127_3211995_0 Phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009949 552.0
HFD2_k127_3211995_1 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004871 473.0
HFD2_k127_3211995_10 Coagulation factor 5/8 C-terminal domain, discoidin domain - - - 0.0000000000001228 85.0
HFD2_k127_3211995_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 341.0
HFD2_k127_3211995_3 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 299.0
HFD2_k127_3211995_4 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000004772 198.0
HFD2_k127_3211995_5 Belongs to the DNA glycosylase MPG family K03652 GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 0.0000000000000000000000000000000000000000000003119 173.0
HFD2_k127_3211995_6 PFAM Peptidase M11 gametolysin - - - 0.0000000000000000000000000000000000000000004256 182.0
HFD2_k127_3211995_7 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000003239 140.0
HFD2_k127_3211995_8 cellulase activity - - - 0.0000000000000000000000000000000002746 153.0
HFD2_k127_3211995_9 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000775 76.0
HFD2_k127_3536482_0 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006793,GO:0006796,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009336,GO:0009605,GO:0009987,GO:0009991,GO:0010134,GO:0010438,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019419,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034599,GO:0040007,GO:0042221,GO:0042594,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0061695,GO:0070887,GO:0071496,GO:0071944,GO:1902494,GO:1902503,GO:1990234 2.7.1.25,2.7.7.4 7.644e-197 623.0
HFD2_k127_3536482_1 Phosphoadenosine phosphosulfate reductase family K00957 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 449.0
HFD2_k127_3536482_2 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 415.0
HFD2_k127_3536482_3 Nickel-containing superoxide dismutase K00518 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.15.1.1 0.00000000000000000000000000000000000000003251 163.0
HFD2_k127_3536482_4 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K04091 - 1.14.14.5 0.000000000000000000000000000004622 126.0
HFD2_k127_3536482_5 Type IV pilus biogenesis stability protein PilW - - - 0.0000000000004245 78.0
HFD2_k127_3536482_6 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000001608 68.0
HFD2_k127_3536482_7 signal peptide processing K03100 - 3.4.21.89 0.000000007006 62.0
HFD2_k127_3536482_8 LysM domain - - - 0.0000008488 61.0
HFD2_k127_3560336_0 Lysine-2,3-aminomutase K01843 - 5.4.3.2 4.552e-218 688.0
HFD2_k127_3560336_1 Dyp-type peroxidase family K07223 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004121 272.0
HFD2_k127_3560336_2 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000006856 198.0
HFD2_k127_3560336_3 - - - - 0.000000000000000000000000000005402 129.0
HFD2_k127_3560336_4 PFAM blue (type 1) copper domain protein K00368,K02638 - 1.7.2.1 0.000000000000000001102 93.0
HFD2_k127_3560336_5 Cyclic-di-AMP receptor - - - 0.00000000000000002689 87.0
HFD2_k127_3560336_6 OsmC-like protein K07397 - - 0.00000000000001078 78.0
HFD2_k127_3560336_7 Uncharacterized protein conserved in bacteria (DUF2255) - - - 0.000000001739 63.0
HFD2_k127_3629110_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 404.0
HFD2_k127_3629110_1 D-alanyl-D-alanine carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000003547 231.0
HFD2_k127_3629110_2 light absorption K07255,K21700 - - 0.0000000000000000000000000000000000000002667 156.0
HFD2_k127_3629110_3 Alkylmercury lyase - - - 0.00000000000000004817 89.0
HFD2_k127_3629110_4 D-alanyl-D-alanine carboxypeptidase - - - 0.0000000000000001533 84.0
HFD2_k127_3677862_0 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 403.0
HFD2_k127_3677862_1 PFAM peptidase M24 K01262,K01271,K01274 - 3.4.11.9,3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 335.0
HFD2_k127_3677862_2 EamA-like transporter family - - - 0.000000000002366 74.0
HFD2_k127_3677862_3 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.00000000005103 68.0
HFD2_k127_3723796_0 PFAM regulator of chromosome condensation, RCC1 - - - 0.000000000000000000000000000000000000000000000000000000000002571 235.0
HFD2_k127_3723796_1 - - - - 0.00000000000000000003646 93.0
HFD2_k127_3723796_2 Non-essential cell division protein that could be required for efficient cell constriction - - - 0.0009907 51.0
HFD2_k127_3734093_0 glycine betaine K05847 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000515 362.0
HFD2_k127_3734093_1 Phosphorylase superfamily K00772,K03784 - 2.4.2.1,2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000001951 229.0
HFD2_k127_3734093_2 Binding-protein-dependent transport system inner membrane component K05846 - - 0.00000000000000000000000000000000000000000000000000000001562 206.0
HFD2_k127_3734093_3 Binding-protein-dependent transport system inner membrane component K05846 - - 0.00000000000000000000000000000000000000000000000000001443 205.0
HFD2_k127_3734093_4 Substrate binding domain of ABC-type glycine betaine transport system K05845 - - 0.0000000000000000000000000000000000000000000001456 182.0
HFD2_k127_3734093_5 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000000000000000000000001231 143.0
HFD2_k127_3734093_6 F420-dependent oxidoreductase - - - 0.00000000000000000000000000000000001928 147.0
HFD2_k127_3734093_7 2'-5' RNA ligase superfamily - - - 0.00000000000000000000000000004254 123.0
HFD2_k127_3734093_8 Protein of unknown function (DUF1684) K09164 - - 0.0004857 43.0
HFD2_k127_3746664_0 FGGY family of carbohydrate kinases, N-terminal domain K00853 - 2.7.1.16 4.245e-248 776.0
HFD2_k127_3746664_1 Catalyzes the conversion of L-arabinose to L-ribulose K01804 - 5.3.1.4 2.804e-209 663.0
HFD2_k127_3746664_10 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000001714 162.0
HFD2_k127_3746664_11 Pfam:Pyridox_oxidase - - - 0.00000000000000000000000004831 112.0
HFD2_k127_3746664_12 Pfam:Pyridox_oxidase - - - 0.00000000000000000000000005554 118.0
HFD2_k127_3746664_14 galactose-1-phosphate uridylyltransferase K00965 GO:0003674,GO:0003824,GO:0004335,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006012,GO:0006139,GO:0006464,GO:0006486,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008108,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009056,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009226,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0018130,GO:0019200,GO:0019318,GO:0019320,GO:0019388,GO:0019438,GO:0019538,GO:0033499,GO:0034641,GO:0034645,GO:0034654,GO:0036211,GO:0042125,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044267,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046835,GO:0046872,GO:0046914,GO:0052573,GO:0052574,GO:0055086,GO:0070085,GO:0070569,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.7.12 0.00008702 45.0
HFD2_k127_3746664_2 ABC-type sugar transport system periplasmic component K02058,K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 478.0
HFD2_k127_3746664_3 Belongs to the binding-protein-dependent transport system permease family K02057,K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007301 389.0
HFD2_k127_3746664_4 Monosaccharide ABC transporter ATP-binding protein, CUT2 family K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 355.0
HFD2_k127_3746664_5 Metallopeptidase family M24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 347.0
HFD2_k127_3746664_6 alcohol dehydrogenase K00004,K00008 - 1.1.1.14,1.1.1.303,1.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 322.0
HFD2_k127_3746664_7 purine nucleotide biosynthetic process K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 315.0
HFD2_k127_3746664_8 Putative serine dehydratase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005075 288.0
HFD2_k127_3746664_9 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases K03077 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008742,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0046872,GO:0046914,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576 5.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000007096 270.0
HFD2_k127_3770140_0 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) K01126,K10716 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 617.0
HFD2_k127_3770140_1 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001546 258.0
HFD2_k127_3770140_2 Two component transcriptional regulator, winged helix family K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000001585 234.0
HFD2_k127_3770140_3 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000002422 236.0
HFD2_k127_3770140_4 histidine kinase A domain protein K02484 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000004787 228.0
HFD2_k127_3770140_5 - - - - 0.0000000000000000000000000000000000001106 146.0
HFD2_k127_3794646_0 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 9.509e-228 715.0
HFD2_k127_3794646_1 Biotin carboxylase C-terminal domain K01941,K11263 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 6.3.4.14,6.3.4.6,6.4.1.2,6.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 398.0
HFD2_k127_3794646_10 YGGT family - - - 0.000001016 57.0
HFD2_k127_3794646_11 - - - - 0.0002001 52.0
HFD2_k127_3794646_2 Cellulose biosynthesis protein BcsQ K03496 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000001485 261.0
HFD2_k127_3794646_3 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000447 257.0
HFD2_k127_3794646_4 PFAM Haloacid dehalogenase domain protein hydrolase K01560,K07025 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000003093 237.0
HFD2_k127_3794646_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000009561 218.0
HFD2_k127_3794646_6 methyltransferase - - - 0.000000000000000000000000000000000000000000000000002635 189.0
HFD2_k127_3794646_7 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000002507 173.0
HFD2_k127_3794646_8 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000002824 137.0
HFD2_k127_3794646_9 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate - - - 0.000000000000000000000000009901 121.0
HFD2_k127_3834234_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 514.0
HFD2_k127_3834234_1 3-methyladenine DNA glycosylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007063 258.0
HFD2_k127_3834234_2 endonuclease III - - - 0.00000000000000000000000000000000000005573 145.0
HFD2_k127_3834234_3 - - - - 0.000000000000000000007002 100.0
HFD2_k127_3834234_4 cellulose binding - - - 0.0009663 51.0
HFD2_k127_3905602_0 Nucleotidyl transferase K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006554 483.0
HFD2_k127_3905602_1 ATPases associated with a variety of cellular activities K10112,K10195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 444.0
HFD2_k127_3905602_10 diguanylate cyclase - - - 0.00000000000000000000000000000000000000003466 173.0
HFD2_k127_3905602_11 PFAM NUDIX hydrolase K01515 - 3.6.1.13 0.0000000000000000000000000000000000000006265 157.0
HFD2_k127_3905602_12 TIR domain - - - 0.000000000000000000000000000000000008701 153.0
HFD2_k127_3905602_13 - - - - 0.0000000000000000000000000000007238 140.0
HFD2_k127_3905602_14 TIR domain - - - 0.000000000000000000000000000001283 134.0
HFD2_k127_3905602_15 Belongs to the NUDIX hydrolase family - - - 0.00000000000000000000000000006553 123.0
HFD2_k127_3905602_16 GCN5-related N-acetyl-transferase K06975 - - 0.00000000000000000000001214 109.0
HFD2_k127_3905602_17 Protein of unknown function (DUF4231) - - - 0.000000000000000000007716 108.0
HFD2_k127_3905602_18 Cys-tRNA(Pro) hydrolase activity K19055 - - 0.0000000000000000001734 96.0
HFD2_k127_3905602_19 TfoX N-terminal domain - - - 0.0000000000000000007479 91.0
HFD2_k127_3905602_2 Signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 424.0
HFD2_k127_3905602_20 Zinc metalloprotease (Elastase) - - - 0.0000000000001645 84.0
HFD2_k127_3905602_21 - - - - 0.00000000005042 70.0
HFD2_k127_3905602_22 Transglycosylase associated protein - - - 0.000000002413 61.0
HFD2_k127_3905602_23 Family of unknown function (DUF5317) - - - 0.0000002068 60.0
HFD2_k127_3905602_24 PFAM LysM domain - - - 0.0000002162 63.0
HFD2_k127_3905602_25 Tetratricopeptide repeat - - - 0.00001036 54.0
HFD2_k127_3905602_3 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 397.0
HFD2_k127_3905602_4 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000053 374.0
HFD2_k127_3905602_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000002441 234.0
HFD2_k127_3905602_6 PFAM Peptidase M11 gametolysin - - - 0.0000000000000000000000000000000000000000000000000000000003392 227.0
HFD2_k127_3905602_7 Protease prsW family - - - 0.00000000000000000000000000000000000000000000000002526 199.0
HFD2_k127_3905602_8 Thioredoxin K03672 - 1.8.1.8 0.0000000000000000000000000000000000000000003382 166.0
HFD2_k127_3905602_9 Flavodoxin domain K00230 - 1.3.5.3 0.00000000000000000000000000000000000000001072 160.0
HFD2_k127_3957590_0 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 346.0
HFD2_k127_3957590_1 Helix-hairpin-helix class 2 (Pol1 family) motifs - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000768 323.0
HFD2_k127_3957590_2 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000168 286.0
HFD2_k127_3957590_3 ROK family K00886 - 2.7.1.63 0.0000000000000000000000000000000000000000000000000000000000000001721 231.0
HFD2_k127_3957590_4 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000003625 235.0
HFD2_k127_3957590_5 efflux transmembrane transporter activity K02004 - - 0.00000000000000007255 95.0
HFD2_k127_3962232_0 Belongs to the MurCDEF family K03802 - 6.3.2.29,6.3.2.30 0.0 1133.0
HFD2_k127_3962232_1 Peptidase family S51 K13282 - 3.4.15.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004893 278.0
HFD2_k127_3962232_2 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000222 241.0
HFD2_k127_3962232_3 Mur ligase middle domain K03802 - 6.3.2.29,6.3.2.30 0.000000000000000000000000000000000000000000000000002297 194.0
HFD2_k127_3962232_4 Belongs to the peptidase S8 family - - - 0.000000000007073 78.0
HFD2_k127_3962232_5 Non-essential cell division protein that could be required for efficient cell constriction - - - 0.00001301 57.0
HFD2_k127_3962232_6 Non-essential cell division protein that could be required for efficient cell constriction - - - 0.00004205 56.0
HFD2_k127_3962232_7 Glycosyltransferase family 87 - - - 0.00009984 53.0
HFD2_k127_4039027_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005906 446.0
HFD2_k127_4039027_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 407.0
HFD2_k127_4039027_2 Beta-galactosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 361.0
HFD2_k127_4039027_3 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 321.0
HFD2_k127_4039027_4 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 293.0
HFD2_k127_4039027_6 Tellurite resistance protein TerB - - - 0.00000000000000000000000001983 113.0
HFD2_k127_4039027_7 RDD family - - - 0.00000000002083 74.0
HFD2_k127_4109625_0 TIGRFAM single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 359.0
HFD2_k127_4109625_1 Required for morphogenesis under gluconeogenic growth conditions - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009732 338.0
HFD2_k127_4109625_2 Displays ATPase and GTPase activities K06958 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000005976 250.0
HFD2_k127_4109625_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K03074,K12257 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000005041 200.0
HFD2_k127_4109625_4 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000001304 211.0
HFD2_k127_4109625_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.00000000000000000000000000000000000000003818 162.0
HFD2_k127_4109625_6 May be required for sporulation K09762 - - 0.000000000000000001064 99.0
HFD2_k127_4109625_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000003697 68.0
HFD2_k127_4109625_8 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0001367 48.0
HFD2_k127_4166511_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.605e-205 657.0
HFD2_k127_4166511_1 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 366.0
HFD2_k127_4166511_2 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.00000000000000000000000000000000000000000000000000000003879 206.0
HFD2_k127_4166511_3 PFAM phosphoesterase, RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000002096 190.0
HFD2_k127_4166511_4 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000008586 111.0
HFD2_k127_4166511_5 nucleic-acid-binding protein implicated in transcription termination K07742 - - 0.000000000000000000002371 99.0
HFD2_k127_4277395_0 PFAM Amidohydrolase family K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003264 392.0
HFD2_k127_4277395_1 TIGRFAM Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 316.0
HFD2_k127_4277395_2 Formiminotransferase domain, N-terminal subdomain K00603,K13990 - 2.1.2.5,4.3.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 308.0
HFD2_k127_4277395_3 Zn peptidase - - - 0.000000000000000000000000000000000000000000000001806 192.0
HFD2_k127_4277395_4 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000618 136.0
HFD2_k127_4292003_0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001315 282.0
HFD2_k127_4292003_1 MazG nucleotide pyrophosphohydrolase domain K02428,K02499,K04765 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66,3.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000003814 263.0
HFD2_k127_4292003_2 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.0000000000000000000000000000000000000000001125 167.0
HFD2_k127_4292003_3 SurA N-terminal domain K03770 - 5.2.1.8 0.000009134 59.0
HFD2_k127_4298881_0 Glycosyl transferase family group 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 474.0
HFD2_k127_4298881_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 350.0
HFD2_k127_4298881_2 domain, Protein K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000003672 196.0
HFD2_k127_4298881_3 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000002082 181.0
HFD2_k127_4298881_4 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000008682 176.0
HFD2_k127_4298881_5 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000002578 149.0
HFD2_k127_4298881_6 ubiE/COQ5 methyltransferase family - - - 0.000000000000002797 85.0
HFD2_k127_4298881_7 - - - - 0.00000000004042 76.0
HFD2_k127_4298881_8 - - - - 0.00000008636 63.0
HFD2_k127_4371064_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 421.0
HFD2_k127_4371064_1 Acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000591 298.0
HFD2_k127_4371064_2 AMP-binding enzyme K22319 - 6.1.3.1 0.0006108 48.0
HFD2_k127_4382922_0 Methylenetetrahydrofolate reductase K00297,K00547,K00548 - 1.5.1.20,2.1.1.10,2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005812 567.0
HFD2_k127_4382922_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000008691 243.0
HFD2_k127_4382922_2 TPM domain K06872 - - 0.00001961 57.0
HFD2_k127_4382922_3 PFAM Rubrerythrin - - - 0.0003881 44.0
HFD2_k127_4413135_0 xanthine dehydrogenase activity - - - 8.285e-214 689.0
HFD2_k127_4413135_1 Malate synthase K01638 - 2.3.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 582.0
HFD2_k127_4413135_2 N-acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000007359 210.0
HFD2_k127_4413135_3 [2Fe-2S] binding domain K03518,K20446 - 1.17.1.5,1.2.5.3 0.00000000000000000000000000000000000000000000000000002148 192.0
HFD2_k127_4413135_4 xanthine dehydrogenase activity K13479 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000005031 194.0
HFD2_k127_4413135_5 Cupin 2, conserved barrel domain protein K19547 - 5.3.3.19 0.0000000000000000000003344 102.0
HFD2_k127_4413135_6 Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000007254 98.0
HFD2_k127_442165_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008818 416.0
HFD2_k127_442165_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 386.0
HFD2_k127_442165_10 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000000001956 202.0
HFD2_k127_442165_11 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000000000001995 201.0
HFD2_k127_442165_12 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.000000000000000000000000000000000000000000000000000001019 198.0
HFD2_k127_442165_13 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000209 190.0
HFD2_k127_442165_14 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000007055 167.0
HFD2_k127_442165_15 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000001327 159.0
HFD2_k127_442165_16 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.00000000000000000000000000000000000000001447 154.0
HFD2_k127_442165_17 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000008739 133.0
HFD2_k127_442165_18 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.000000000000000000000000000000004777 141.0
HFD2_k127_442165_19 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000002663 121.0
HFD2_k127_442165_2 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001157 282.0
HFD2_k127_442165_20 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.000000000000000000000000000002769 124.0
HFD2_k127_442165_21 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000001742 113.0
HFD2_k127_442165_22 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000006148 103.0
HFD2_k127_442165_23 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.000000000000000000000198 100.0
HFD2_k127_442165_24 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000001027 103.0
HFD2_k127_442165_25 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000004927 74.0
HFD2_k127_442165_26 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000009721 65.0
HFD2_k127_442165_27 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000001888 50.0
HFD2_k127_442165_28 Ribosomal L29 protein K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000007556 53.0
HFD2_k127_442165_29 50S ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0003982 46.0
HFD2_k127_442165_3 Methionine aminopeptidase K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007478 276.0
HFD2_k127_442165_4 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001753 270.0
HFD2_k127_442165_5 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003936 249.0
HFD2_k127_442165_6 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000000000000001198 240.0
HFD2_k127_442165_7 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000000000000664 231.0
HFD2_k127_442165_8 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000001098 216.0
HFD2_k127_442165_9 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000002386 224.0
HFD2_k127_4505316_0 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 458.0
HFD2_k127_4505316_1 Required for the activity of the bacterial periplasmic transport system of putrescine K02055 GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009290,GO:0009292,GO:0009294,GO:0009987,GO:0015931,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042618,GO:0042619,GO:0044464,GO:0044764,GO:0050657,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0071702,GO:0071704,GO:0071705,GO:0098657,GO:1901440,GO:1901441,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 418.0
HFD2_k127_4505316_2 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 335.0
HFD2_k127_4505316_3 Carbon-nitrogen hydrolase K01431 - 3.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 313.0
HFD2_k127_4505316_4 Protein of unknown function (DUF2652) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004617 313.0
HFD2_k127_4505316_5 PFAM binding-protein-dependent transport systems inner membrane component K02053 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001697 277.0
HFD2_k127_4505316_6 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000001869 221.0
HFD2_k127_4505316_7 Tachylectin - - - 0.000000000000000000000009285 113.0
HFD2_k127_4505316_8 Belongs to the bacterial solute-binding protein 3 family K02030 - - 0.000000000000002573 87.0
HFD2_k127_4511857_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000773 446.0
HFD2_k127_4511857_1 TIGRFAM fructose-1,6-bisphosphatase, class II K02446 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 385.0
HFD2_k127_4511857_2 nitrite transmembrane transporter activity K02532 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000073 317.0
HFD2_k127_4511857_3 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000005616 222.0
HFD2_k127_4511857_4 Alkaline phosphatase K01113 - 3.1.3.1 0.000000000000000000000000000000000000000000000000000000004149 204.0
HFD2_k127_4511857_5 - - - - 0.0000000000000000000000000000000000000000000002764 175.0
HFD2_k127_4511857_6 - - - - 0.0003502 49.0
HFD2_k127_4511857_7 Mannose-6-phosphate isomerase - - - 0.0007768 49.0
HFD2_k127_4517047_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 375.0
HFD2_k127_4517047_1 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627,K00658,K09699 - 2.3.1.12,2.3.1.168,2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 352.0
HFD2_k127_4517047_10 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.000000000000000000000000001908 118.0
HFD2_k127_4517047_11 3-demethylubiquinone-9 3-O-methyltransferase activity K03428 - 2.1.1.11 0.0000000000000000002404 99.0
HFD2_k127_4517047_12 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000008157 86.0
HFD2_k127_4517047_13 Non-essential cell division protein that could be required for efficient cell constriction - - - 0.000000004433 70.0
HFD2_k127_4517047_14 FtsZ-dependent cytokinesis - - - 0.000004554 52.0
HFD2_k127_4517047_15 Non-essential cell division protein that could be required for efficient cell constriction - - - 0.00008678 55.0
HFD2_k127_4517047_16 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000947 55.0
HFD2_k127_4517047_2 Belongs to the serpin family K13963 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003836 300.0
HFD2_k127_4517047_3 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000005386 220.0
HFD2_k127_4517047_4 Protein of unknown function (DUF664) - - - 0.00000000000000000000000000000000000000000000000000007142 194.0
HFD2_k127_4517047_5 RIO1 family K07178 - 2.7.11.1 0.00000000000000000000000000000000000000000000001856 182.0
HFD2_k127_4517047_6 DinB family - - - 0.0000000000000000000000000000000000000000000006197 171.0
HFD2_k127_4517047_7 PAC2 family - - - 0.000000000000000000000000000000000000000000003989 175.0
HFD2_k127_4517047_8 - - - - 0.00000000000000000000000000000000007194 145.0
HFD2_k127_4584608_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531,K01537,K12952 - 3.6.3.2,3.6.3.8 1.662e-195 640.0
HFD2_k127_4584608_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000002832 89.0
HFD2_k127_4584608_2 Modulates RecA activity K03565 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000001222 76.0
HFD2_k127_4584608_3 VanZ like family - - - 0.0000006117 58.0
HFD2_k127_4594125_0 Protein of unknown function, DUF255 K06888 - - 7.104e-217 692.0
HFD2_k127_4594125_1 protein related to plant photosystem II stability assembly factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 497.0
HFD2_k127_4594125_10 Sugar-specific transcriptional regulator TrmB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009178 291.0
HFD2_k127_4594125_11 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000001946 263.0
HFD2_k127_4594125_12 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000001532 213.0
HFD2_k127_4594125_13 transcriptional regulator - - - 0.000000000000000000000000000000000001862 157.0
HFD2_k127_4594125_14 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - - 0.000000000000000000000000000009973 132.0
HFD2_k127_4594125_15 ThiS family - - - 0.0000000000000000000021 96.0
HFD2_k127_4594125_16 Copper resistance protein K07156 - - 0.000000003244 70.0
HFD2_k127_4594125_17 Copper binding proteins, plastocyanin/azurin family - - - 0.0003186 50.0
HFD2_k127_4594125_2 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007334 392.0
HFD2_k127_4594125_3 PFAM Binding-protein-dependent transport system inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 382.0
HFD2_k127_4594125_4 Peptidase family M20/M25/M40 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 383.0
HFD2_k127_4594125_5 ADP-glyceromanno-heptose 6-epimerase activity K01710,K01784 - 4.2.1.46,5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004931 334.0
HFD2_k127_4594125_6 Belongs to the N(4) N(6)-methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 334.0
HFD2_k127_4594125_7 Glycosyl hydrolases family 43 K01198,K01209 - 3.2.1.37,3.2.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 328.0
HFD2_k127_4594125_8 Glycosyl hydrolase family 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006544 317.0
HFD2_k127_4594125_9 Galactokinase galactose-binding signature K00849 - 2.7.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005549 315.0
HFD2_k127_4601377_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 548.0
HFD2_k127_4601377_1 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 321.0
HFD2_k127_4601377_2 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 315.0
HFD2_k127_4601377_3 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000005764 188.0
HFD2_k127_4601377_4 inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000291 178.0
HFD2_k127_4601377_5 Cd(II) Pb(II)-responsive transcriptional regulator - - - 0.0000000000000000008224 92.0
HFD2_k127_4601377_6 Cation efflux family - - - 0.00000000004367 72.0
HFD2_k127_4601377_7 Polyketide cyclase / dehydrase and lipid transport - - - 0.000003718 57.0
HFD2_k127_4737896_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003787 274.0
HFD2_k127_4737896_1 amine dehydrogenase activity K08282,K08884 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009405,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010565,GO:0016020,GO:0016021,GO:0016036,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0030145,GO:0030312,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031667,GO:0031668,GO:0031669,GO:0032091,GO:0033554,GO:0036211,GO:0042304,GO:0042594,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043393,GO:0043412,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051100,GO:0051704,GO:0051716,GO:0062012,GO:0062014,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000008192 242.0
HFD2_k127_4737896_2 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.000000000000000000000000000000000000000000000000000000000000000001553 235.0
HFD2_k127_4737896_3 ResB-like family K07399 - - 0.000000000000000000000000000000000000000001337 163.0
HFD2_k127_4737896_4 cytochrome complex assembly - - - 0.000000000000000000000000000001197 136.0
HFD2_k127_4737896_5 TIGRFAM cytochrome C family protein - - - 0.00000000000000000008761 105.0
HFD2_k127_4737896_6 PFAM PKD domain containing protein - - - 0.0000000001975 74.0
HFD2_k127_4737896_8 peptidyl-tyrosine sulfation - - - 0.00000000194 61.0
HFD2_k127_4741346_0 Belongs to the xylose isomerase family K01805 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0071704,GO:1901575 5.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006532 597.0
HFD2_k127_4741346_1 PFAM carbohydrate kinase K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 580.0
HFD2_k127_4741346_2 Belongs to the binding-protein-dependent transport system permease family K10544 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 429.0
HFD2_k127_4741346_3 ATPases associated with a variety of cellular activities K10545 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357 348.0
HFD2_k127_4741346_4 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000001981 130.0
HFD2_k127_4741346_5 Aldose 1-epimerase K01785 - 5.1.3.3 0.000000000000000000004785 108.0
HFD2_k127_4741346_6 ABC transporter substrate-binding protein K10543 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005975,GO:0005996,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0015749,GO:0015750,GO:0015753,GO:0019321,GO:0030246,GO:0030288,GO:0030313,GO:0031975,GO:0034219,GO:0036094,GO:0042597,GO:0042732,GO:0044238,GO:0044281,GO:0044464,GO:0048029,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704 - 0.00002072 49.0
HFD2_k127_4779715_0 Penicillin-binding protein 2 K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006367 377.0
HFD2_k127_4779715_1 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001712 258.0
HFD2_k127_4779715_2 Protein of unknown function (DUF1385) K09153 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001634 252.0
HFD2_k127_4779715_3 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000004175 116.0
HFD2_k127_4779715_4 Binds the 23S rRNA K02909 - - 0.00000000000000000000000199 105.0
HFD2_k127_4779715_5 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000175 100.0
HFD2_k127_4779715_6 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000005576 63.0
HFD2_k127_4779715_7 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins - - - 0.00000183 58.0
HFD2_k127_4785394_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 587.0
HFD2_k127_4785394_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 502.0
HFD2_k127_4785394_2 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 446.0
HFD2_k127_4785394_3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000355 371.0
HFD2_k127_4785394_4 response regulator K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 289.0
HFD2_k127_4785394_5 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000006676 216.0
HFD2_k127_4785394_6 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.0000000000000000000000000000000000000000000000000000001702 202.0
HFD2_k127_4785394_7 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000006299 182.0
HFD2_k127_4785394_8 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.00000000000000000000000000000000000007902 148.0
HFD2_k127_4785394_9 Domain of unknown function (DUF4115) - - - 0.000000000000005983 88.0
HFD2_k127_4966289_0 Isocitrate lyase K01637 GO:0003674,GO:0003824,GO:0004451,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0006102,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046421,GO:0046487,GO:0071704,GO:0072350 4.1.3.1 0.0 1126.0
HFD2_k127_4966289_1 ABC transporter, transmembrane region K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006761 511.0
HFD2_k127_4966289_10 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000002812 73.0
HFD2_k127_4966289_2 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 434.0
HFD2_k127_4966289_3 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 385.0
HFD2_k127_4966289_4 MgtE intracellular N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004443 361.0
HFD2_k127_4966289_5 NADH flavin oxidoreductase NADH oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 324.0
HFD2_k127_4966289_6 Natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 308.0
HFD2_k127_4966289_7 Memo-like protein K06990 - - 0.0000000000000000000000000003987 128.0
HFD2_k127_4966289_8 ACT domain protein - - - 0.0000000000000000000000327 106.0
HFD2_k127_4966289_9 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000009941 99.0
HFD2_k127_501535_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 6.2.1.1 2.051e-204 646.0
HFD2_k127_501535_1 Mechanosensitive ion channel K22044 - - 0.000000000000000000000000000000000000000000000004087 186.0
HFD2_k127_501535_2 N-4 methylation of cytosine K00590 - 2.1.1.113 0.00000000001002 79.0
HFD2_k127_5033587_0 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009896 293.0
HFD2_k127_5033587_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005943 270.0
HFD2_k127_5033587_2 D-aminopeptidase K16203 - - 0.00000000000000000000000000000000000000000000000000000000000006532 222.0
HFD2_k127_5033587_3 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000009846 205.0
HFD2_k127_5033587_4 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000002292 206.0
HFD2_k127_5033587_5 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000002111 175.0
HFD2_k127_5033587_6 Molybdopterin converting factor subunit K03635,K21142 - 2.8.1.12 0.0000000000000000000000000000000000000001243 165.0
HFD2_k127_5033587_7 Histidine kinase K07675 - 2.7.13.3 0.000000000002954 72.0
HFD2_k127_5033587_9 Cytochrome c - - - 0.00000002362 63.0
HFD2_k127_5057662_0 Aminotransferase class-III K00823 - 2.6.1.19 9.27e-198 642.0
HFD2_k127_5057662_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000002662 218.0
HFD2_k127_5057662_2 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K01259 - 3.4.11.5 0.00000000000000000000000000000005275 127.0
HFD2_k127_5057662_3 acetyltransferase - - - 0.000000000000000000002797 105.0
HFD2_k127_5057662_4 response regulator - - - 0.00000001933 66.0
HFD2_k127_5061718_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 4.518e-279 880.0
HFD2_k127_5061718_1 Putative Flp pilus-assembly TadE/G-like - - - 0.0007738 51.0
HFD2_k127_5096007_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005706 439.0
HFD2_k127_5096007_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008125 349.0
HFD2_k127_5096007_2 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009507 327.0
HFD2_k127_5096007_3 PFAM regulator of chromosome condensation, RCC1 - - - 0.000000000000000000000000000000000000000000000000000000001174 230.0
HFD2_k127_5096007_4 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000008684 190.0
HFD2_k127_5096007_5 Uncharacterised protein family UPF0047 - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000003179 179.0
HFD2_k127_5096007_6 PA14 - - - 0.000000000000000000000000000000000001941 161.0
HFD2_k127_5096007_7 Protein of unknown function DUF58 - - - 0.00000000000000000000000005624 121.0
HFD2_k127_5096007_8 - - - - 0.00000002726 68.0
HFD2_k127_5096007_9 Belongs to the UPF0235 family K09131 - - 0.000001457 59.0
HFD2_k127_5278919_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 494.0
HFD2_k127_5278919_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 403.0
HFD2_k127_5278919_2 Putative zinc- or iron-chelating domain - - - 0.00000000000000000000000000000000000000000000000001602 193.0
HFD2_k127_5278919_3 phosphatidylcholine-hydrolyzing phospholipase - - - 0.000000000000000001758 100.0
HFD2_k127_5278919_4 Major Facilitator Superfamily - - - 0.00000000000000002074 95.0
HFD2_k127_5278919_5 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - 0.00000000000000002665 94.0
HFD2_k127_5278919_6 Domain of unknown function (DUF1906) - - - 0.0000000001757 72.0
HFD2_k127_531423_0 DEAD-like helicases superfamily K03724,K06877 - - 0.0 1517.0
HFD2_k127_531423_1 signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 331.0
HFD2_k127_531423_2 Peptidase inhibitor I9 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000259 320.0
HFD2_k127_531423_3 Belongs to the FPG family K05522 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000005569 199.0
HFD2_k127_531423_4 cellulase activity - - - 0.000000000000000002034 102.0
HFD2_k127_531423_5 ECF sigma factor K03088 - - 0.00000000009342 69.0
HFD2_k127_5394374_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1125.0
HFD2_k127_5394374_1 PFAM Glucose Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004964 366.0
HFD2_k127_5394374_2 Glycogen debranching enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003358 290.0
HFD2_k127_5394374_3 MMPL family K06994,K20470 - - 0.00000000000000000000000000000000000000000000000000000000000000000001466 251.0
HFD2_k127_5434957_0 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 538.0
HFD2_k127_5434957_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 381.0
HFD2_k127_5434957_2 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009556 292.0
HFD2_k127_5434957_3 homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000002859 262.0
HFD2_k127_5434957_4 ACT domain K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000007746 208.0
HFD2_k127_5434957_5 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.0000000000000000000000000000000000000000000007426 180.0
HFD2_k127_5434957_6 Aldo/keto reductase family - - - 0.0000000000000000000000004857 120.0
HFD2_k127_5441093_0 Adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 351.0
HFD2_k127_5441093_1 Adenosine/AMP deaminase K01488 - 3.5.4.4 0.000000000000000000000000000000000000000000000000000000006768 212.0
HFD2_k127_5441093_2 TIR domain - - - 0.0000000000000000000000000001547 127.0
HFD2_k127_5441093_3 SMART Peptidoglycan-binding LysM - - - 0.0000000000000000000000000003579 122.0
HFD2_k127_5441093_4 Peptidase A24A, prepilin type IV K02654 - 3.4.23.43 0.000000000002505 77.0
HFD2_k127_5465504_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 2.209e-213 676.0
HFD2_k127_5465504_1 PFAM peptidase S58, DmpA K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 376.0
HFD2_k127_5465504_2 SnoaL-like domain - - - 0.0000000004085 68.0
HFD2_k127_5541810_0 Phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.0 1228.0
HFD2_k127_5541810_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 5.128e-219 704.0
HFD2_k127_5541810_10 DsrE/DsrF/DrsH-like family - - - 0.00000000000000001285 88.0
HFD2_k127_5541810_11 multicopper - - - 0.000000000000001849 81.0
HFD2_k127_5541810_12 PFAM CBS domain K07182 - - 0.0000000000000135 84.0
HFD2_k127_5541810_13 PFAM Vitamin K epoxide reductase - - - 0.000000000000069 79.0
HFD2_k127_5541810_14 - - - - 0.00000000000008506 77.0
HFD2_k127_5541810_15 PspC domain K03973 - - 0.000000000295 69.0
HFD2_k127_5541810_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K03737 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 618.0
HFD2_k127_5541810_3 PFAM Acetyl-CoA hydrolase transferase K01067 - 3.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 306.0
HFD2_k127_5541810_4 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925,K00932 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006083,GO:0006091,GO:0006113,GO:0006520,GO:0006566,GO:0006567,GO:0006629,GO:0006631,GO:0006633,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0008776,GO:0008980,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009987,GO:0015980,GO:0016053,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019541,GO:0019542,GO:0019665,GO:0019666,GO:0019752,GO:0032787,GO:0042710,GO:0043167,GO:0043169,GO:0043436,GO:0044010,GO:0044011,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046394,GO:0046395,GO:0046459,GO:0046872,GO:0046914,GO:0051703,GO:0051704,GO:0051790,GO:0055114,GO:0071704,GO:0072330,GO:0090605,GO:0090609,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901605,GO:1901606 2.7.2.1,2.7.2.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000004042 273.0
HFD2_k127_5541810_5 PFAM Acetyl-CoA hydrolase transferase K01067 - 3.1.2.1 0.000000000000000000000000000000000000000000000000000000008536 204.0
HFD2_k127_5541810_6 Thioredoxin - - - 0.00000000000000000000000000000005895 140.0
HFD2_k127_5541810_7 OsmC-like protein K07397 - - 0.000000000000000000000003463 108.0
HFD2_k127_5541810_8 FMN binding - - - 0.00000000000000000004338 96.0
HFD2_k127_5541810_9 Belongs to the universal stress protein A family - - - 0.0000000000000000001232 99.0
HFD2_k127_5542655_0 ERAP1-like C-terminal domain K01256,K08776 - 3.4.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 586.0
HFD2_k127_5542655_1 tail specific protease K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000001882 266.0
HFD2_k127_5542655_2 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006101 255.0
HFD2_k127_5542655_3 Acetyltransferase (GNAT) domain K22479 - - 0.000000000000000000000000000000000000000000000000000000006771 209.0
HFD2_k127_5542655_4 lipid kinase activity - - - 0.000000000000000000000000000000000000000000000000002422 194.0
HFD2_k127_5542655_5 HxlR-like helix-turn-helix - - - 0.000000000000000000000000000967 119.0
HFD2_k127_5575302_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002467 354.0
HFD2_k127_5575302_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000001909 254.0
HFD2_k127_5575302_2 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000013 199.0
HFD2_k127_5575302_3 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.000000000000000000000000000000000000000004887 161.0
HFD2_k127_5575302_4 ATPase or kinase K06925 GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000000000004883 119.0
HFD2_k127_5575302_5 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000002923 90.0
HFD2_k127_5575302_6 PFAM Peptidase M22, glycoprotease K14742 GO:0002949,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0071944,GO:0090304,GO:1901360 - 0.0000000000000001834 89.0
HFD2_k127_5575302_7 - - - - 0.0001954 50.0
HFD2_k127_5827469_0 PFAM carboxyl transferase K01969,K15052 - 2.1.3.15,6.4.1.3,6.4.1.4 4.023e-229 721.0
HFD2_k127_5827469_1 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000006682 207.0
HFD2_k127_5827469_2 MOSC domain - - - 0.000000000000000000000000000000000006638 140.0
HFD2_k127_5827469_3 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000002307 138.0
HFD2_k127_5827469_4 Receptor family ligand binding region K01999,K11954 - - 0.0000000000000000000004152 112.0
HFD2_k127_5827469_5 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000001051 100.0
HFD2_k127_5827469_6 Domain of unknown function (DUF296) K06934 - - 0.000000000000000005107 93.0
HFD2_k127_5827469_7 ECF sigma factor K03088 - - 0.000000000000004534 79.0
HFD2_k127_5827469_8 Tetratricopeptide repeat - - - 0.000000000001207 81.0
HFD2_k127_5892547_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 507.0
HFD2_k127_5892547_1 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008575 350.0
HFD2_k127_5892547_10 VanW like protein - - - 0.000000000000000000000000002686 129.0
HFD2_k127_5892547_11 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000004835 104.0
HFD2_k127_5892547_12 domain, Protein K09766 - - 0.0000000003244 74.0
HFD2_k127_5892547_14 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000007406 66.0
HFD2_k127_5892547_15 - - - - 0.00000006601 63.0
HFD2_k127_5892547_16 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0002104 48.0
HFD2_k127_5892547_2 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 333.0
HFD2_k127_5892547_3 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006038 262.0
HFD2_k127_5892547_4 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000002712 229.0
HFD2_k127_5892547_5 competence protein COMEC - - - 0.000000000000000000000000000000000000000000000000000000000002493 225.0
HFD2_k127_5892547_6 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000000000004244 163.0
HFD2_k127_5892547_7 PFAM 60 kDa inner membrane insertion protein K03217 - - 0.000000000000000000000000000005443 135.0
HFD2_k127_5892547_8 PFAM single-stranded nucleic acid binding R3H domain protein K06346 - - 0.00000000000000000000000000007728 130.0
HFD2_k127_5892547_9 tRNA-binding protein K06878 GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0017101,GO:0017102,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000001438 118.0
HFD2_k127_5978834_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 418.0
HFD2_k127_5978834_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007701 406.0
HFD2_k127_5978834_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 368.0
HFD2_k127_5978834_3 Exporter of polyketide antibiotics K01992 - - 0.00000000000000000000000000000000000000000000000001804 192.0
HFD2_k127_5978834_4 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000004692 182.0
HFD2_k127_5978834_5 Cytidylate kinase-like family - - - 0.00000000000000000000000006874 116.0
HFD2_k127_5980586_0 Aspartate-ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 2.031e-199 631.0
HFD2_k127_5980586_1 Amidohydrolase family K01487 GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006144,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008892,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0016814,GO:0018756,GO:0019239,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0046098,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072521,GO:1901360,GO:1901564 3.5.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 319.0
HFD2_k127_5980586_2 N-acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000001462 207.0
HFD2_k127_5980586_3 Iron-containing redox enzyme K06137 - 1.3.3.11 0.000000000000000000000000000000000000000000000000156 184.0
HFD2_k127_5980586_4 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity - - - 0.000000000000000000000000000000000000000131 165.0
HFD2_k127_5980586_5 von Willebrand factor (vWF) type A domain - - - 0.000003614 60.0
HFD2_k127_6009518_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835,K01840 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 422.0
HFD2_k127_6009518_1 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009867 268.0
HFD2_k127_6009518_2 glutamine-fructose-6-phosphate transaminase (isomerizing) activity K00820,K15916 - 2.6.1.16,5.3.1.8,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000005575 246.0
HFD2_k127_6009518_3 Belongs to the mannose-6-phosphate isomerase type 2 family K00971,K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000001573 242.0
HFD2_k127_6009518_4 Abc transporter K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000002075 200.0
HFD2_k127_6009518_5 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.000000000000000000000000000000000000000000000006579 186.0
HFD2_k127_6009518_6 PFAM zinc finger, SWIM domain protein - - - 0.00000000000000000000006372 102.0
HFD2_k127_6146287_0 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004881 565.0
HFD2_k127_6146287_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 456.0
HFD2_k127_6146287_10 peroxiredoxin activity - - - 0.0000000000000000000000000000000000003384 147.0
HFD2_k127_6146287_11 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000001699 139.0
HFD2_k127_6146287_12 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000003914 131.0
HFD2_k127_6146287_13 Hemerythrin hhe cation binding - - - 0.00000000000000000000000000000852 124.0
HFD2_k127_6146287_14 MgtC family K07507 - - 0.000000000000000000000000198 111.0
HFD2_k127_6146287_15 AI-2E family transporter - - - 0.000000000000000001052 99.0
HFD2_k127_6146287_16 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template - - - 0.000000000018 65.0
HFD2_k127_6146287_2 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009842 402.0
HFD2_k127_6146287_3 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K00167 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 396.0
HFD2_k127_6146287_4 Dehydrogenase E1 component K00166 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 374.0
HFD2_k127_6146287_5 Transglycosylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004859 308.0
HFD2_k127_6146287_6 PFAM ABC transporter related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000138 291.0
HFD2_k127_6146287_7 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002959 259.0
HFD2_k127_6146287_8 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000001257 211.0
HFD2_k127_6146287_9 Histidine kinase K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000002986 186.0
HFD2_k127_6205884_0 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 4.97e-234 739.0
HFD2_k127_6205884_1 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000356 487.0
HFD2_k127_6205884_10 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001398 282.0
HFD2_k127_6205884_11 metal-dependent hydrolase with the TIM-barrel fold K07048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001008 271.0
HFD2_k127_6205884_12 Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000001351 213.0
HFD2_k127_6205884_13 KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.0000000000000000000000000000000001782 141.0
HFD2_k127_6205884_14 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000003709 128.0
HFD2_k127_6205884_15 Protein of unknown function (DUF3788) - - - 0.0000000000000000004816 92.0
HFD2_k127_6205884_2 succinate dehydrogenase K00244 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003954 470.0
HFD2_k127_6205884_3 PEP-utilising enzyme, mobile domain K01006 - 2.7.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 464.0
HFD2_k127_6205884_4 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005658 410.0
HFD2_k127_6205884_5 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 408.0
HFD2_k127_6205884_6 ABC-type spermidine putrescine transport system, permease component I K11071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006885 321.0
HFD2_k127_6205884_7 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 317.0
HFD2_k127_6205884_8 PFAM extracellular solute-binding protein family 1 K11069 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007961 308.0
HFD2_k127_6205884_9 Binding-protein-dependent transport system inner membrane component K11070 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009947 292.0
HFD2_k127_6211890_0 peptidase K01295 - 3.4.17.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000525 337.0
HFD2_k127_6211890_1 Peptidase S53 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000542 312.0
HFD2_k127_6211890_2 peptidase activity - - - 0.00000000000000003564 89.0
HFD2_k127_6229900_0 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 4.628e-219 708.0
HFD2_k127_6229900_1 NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007667 541.0
HFD2_k127_6229900_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000003434 105.0
HFD2_k127_6229900_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000002578 90.0
HFD2_k127_6229900_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K14091 - 1.6.5.3 0.000000000000001695 87.0
HFD2_k127_6229900_13 Non-essential cell division protein that could be required for efficient cell constriction - - - 0.000000003711 68.0
HFD2_k127_6229900_14 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00002871 54.0
HFD2_k127_6229900_2 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 477.0
HFD2_k127_6229900_3 NADH dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 378.0
HFD2_k127_6229900_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006402 367.0
HFD2_k127_6229900_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000004335 193.0
HFD2_k127_6229900_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337,K05572 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0045333,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000000001732 163.0
HFD2_k127_6229900_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000006631 139.0
HFD2_k127_6229900_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000003095 111.0
HFD2_k127_6229900_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.00000000000000000000001013 105.0
HFD2_k127_6243392_0 Catalyzes the attachment of glycine to tRNA(Gly) K01880 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 542.0
HFD2_k127_6243392_1 Berberine and berberine like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 359.0
HFD2_k127_6243392_2 PFAM CBS domain containing protein K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001961 291.0
HFD2_k127_6243392_3 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000001062 261.0
HFD2_k127_6243392_4 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000000000000000000000000000000000000006674 186.0
HFD2_k127_6243392_5 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000487 173.0
HFD2_k127_6243392_6 ArsR family transcriptional regulator - - - 0.000000000000000000000000000000002188 134.0
HFD2_k127_6243392_7 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000006195 134.0
HFD2_k127_6243392_8 phosphinothricin N-acetyltransferase activity K00604,K03825 GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234 2.1.2.9 0.00000000000000000008214 103.0
HFD2_k127_6263524_0 Carbamoyl-phosphate synthetase ammonia chain K01955 - 6.3.5.5 1.511e-203 661.0
HFD2_k127_6263524_1 MMPL family K06994 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 418.0
HFD2_k127_6263524_10 Protein of unknown function (DUF1622) - - - 0.0002535 50.0
HFD2_k127_6263524_2 Pyrimidine nucleoside phosphorylase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 350.0
HFD2_k127_6263524_3 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 308.0
HFD2_k127_6263524_4 Truncated hemoglobins K06886 - - 0.00000000000000000000000000000000000000000000000000000000000002532 217.0
HFD2_k127_6263524_5 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000000001453 207.0
HFD2_k127_6263524_6 Ion channel - - - 0.000000000000000000000000000000000000000000000000001402 200.0
HFD2_k127_6263524_7 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000002702 147.0
HFD2_k127_6263524_8 ATP dependent DNA ligase domain K01971 - 6.5.1.1 0.00000000000004269 81.0
HFD2_k127_6263524_9 WD40-like Beta Propeller Repeat - - - 0.0000000005757 72.0
HFD2_k127_6272512_0 Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000002922 225.0
HFD2_k127_6272512_1 lipoyl(octanoyl) transferase activity K03644,K03801 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181,2.8.1.8 0.000000000000000000000000000000000000000000000009302 183.0
HFD2_k127_6272512_2 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000001434 177.0
HFD2_k127_6272512_3 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.000000000000000009903 86.0
HFD2_k127_6272512_4 DNA-templated transcription, initiation K03088 - - 0.00000000000000001711 93.0
HFD2_k127_6272512_5 AntiSigma factor - - - 0.0003426 53.0
HFD2_k127_6273346_0 aminotransferase class I and II K00812,K10907,K14267 - 2.6.1.1,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 522.0
HFD2_k127_6273346_1 Adenosine/AMP deaminase K01488 GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006708 509.0
HFD2_k127_6273346_2 PFAM Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 392.0
HFD2_k127_6273346_3 Sterol carrier protein domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 327.0
HFD2_k127_6273346_4 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000009306 107.0
HFD2_k127_6273346_5 Alpha/beta hydrolase family K07020 - - 0.0000000000000000001597 95.0
HFD2_k127_6273346_6 DNA binding - - - 0.000000003273 66.0
HFD2_k127_6273346_7 Subtilase family - - - 0.0006114 53.0
HFD2_k127_6298079_0 COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002766 248.0
HFD2_k127_6298079_1 - - - - 0.000000000000000000000000006587 121.0
HFD2_k127_6298079_2 Belongs to the ArsC family - - - 0.000000000000000000000000006763 116.0
HFD2_k127_6298079_3 Bulb-type mannose-specific lectin - - - 0.0000000009027 68.0
HFD2_k127_635708_0 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003591 274.0
HFD2_k127_635708_1 GyrI-like small molecule binding domain - - - 0.000000000000000000000000000000000000000008289 162.0
HFD2_k127_635708_3 - - - - 0.000000000000000000000000000000000006533 155.0
HFD2_k127_6520062_0 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 365.0
HFD2_k127_6520062_1 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003058 290.0
HFD2_k127_6520062_2 spore germination - - - 0.0000000000000000000000000000006822 134.0
HFD2_k127_6520062_3 - - - - 0.0000000000003399 81.0
HFD2_k127_6520062_4 COG1020 Non-ribosomal peptide synthetase modules and related proteins - - - 0.000000000004794 68.0
HFD2_k127_6567079_0 PFAM Adenylyl cyclase class-3 4 guanylyl cyclase - - - 2.269e-220 724.0
HFD2_k127_6567079_1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000859 288.0
HFD2_k127_6567079_2 Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway K15525 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0010125,GO:0010126,GO:0016020,GO:0016137,GO:0016138,GO:0016787,GO:0016810,GO:0016811,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 3.5.1.103 0.00000000000000000000000000000000000000000000000000000000001181 216.0
HFD2_k127_6567079_3 Capsule synthesis protein, CapA K07282 - - 0.00000000000000000000000000000007571 131.0
HFD2_k127_6588021_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 6.871e-234 760.0
HFD2_k127_6588021_1 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001426 243.0
HFD2_k127_6588021_2 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000007918 230.0
HFD2_k127_6588021_3 Regulatory protein, FmdB family - - - 0.0000000002044 66.0
HFD2_k127_659943_0 peptidase K01295 - 3.4.17.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009497 289.0
HFD2_k127_659943_1 Pro-kumamolisin, activation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001555 291.0
HFD2_k127_659943_2 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000005325 145.0
HFD2_k127_659943_3 peptidase activity - - - 0.000000000000000000000000006901 124.0
HFD2_k127_6623569_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 2.298e-194 623.0
HFD2_k127_6623569_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 395.0
HFD2_k127_6623569_2 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000008022 93.0
HFD2_k127_6623569_3 PFAM YbbR-like protein - - - 0.000000001282 70.0
HFD2_k127_6779007_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 5.582e-263 824.0
HFD2_k127_6779007_1 Heat shock 70 kDa protein K04043 - - 2.529e-260 818.0
HFD2_k127_6779007_10 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000002765 212.0
HFD2_k127_6779007_11 Galactose oxidase, central domain - - - 0.0000000000000000000000000000000000001507 155.0
HFD2_k127_6779007_12 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0017076,GO:0030234,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0044464,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0071496,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000004341 145.0
HFD2_k127_6779007_13 - - - - 0.00000000001505 67.0
HFD2_k127_6779007_14 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000001097 71.0
HFD2_k127_6779007_15 - - - - 0.0000000002512 63.0
HFD2_k127_6779007_16 PhoQ Sensor - - - 0.000007031 60.0
HFD2_k127_6779007_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 556.0
HFD2_k127_6779007_3 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005513 483.0
HFD2_k127_6779007_4 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007603 467.0
HFD2_k127_6779007_5 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 422.0
HFD2_k127_6779007_6 metallocarboxypeptidase activity K05996 - 3.4.17.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 315.0
HFD2_k127_6779007_7 Involved in the biosynthesis of porphyrin-containing compound - GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004258 285.0
HFD2_k127_6779007_8 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004879 263.0
HFD2_k127_6779007_9 Uridine phosphorylase K00757 - 2.4.2.3 0.00000000000000000000000000000000000000000000000000000000000000005636 232.0
HFD2_k127_6780530_0 ABC transporter transmembrane region K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005558 365.0
HFD2_k127_6780530_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001167 265.0
HFD2_k127_6780530_2 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000001492 184.0
HFD2_k127_6780530_3 Sulfotransferase domain - - - 0.00000000000000000000000000000000000001455 158.0
HFD2_k127_6780530_4 Sulfotransferase domain - - - 0.000000000000000000000000000000004429 141.0
HFD2_k127_6780530_5 Phosphotransferase enzyme family - - - 0.0000000005131 70.0
HFD2_k127_694350_0 'PFAM Alpha amylase, catalytic K01187 - 3.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007234 610.0
HFD2_k127_694350_1 Belongs to the peptidase M50B family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 323.0
HFD2_k127_694350_2 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002752 275.0
HFD2_k127_694350_3 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000002206 235.0
HFD2_k127_694350_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000005911 240.0
HFD2_k127_694350_5 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000001187 153.0
HFD2_k127_694350_6 - - - - 0.00000000000000007466 91.0
HFD2_k127_694350_7 Copper binding proteins, plastocyanin/azurin family - - - 0.000000000001736 78.0
HFD2_k127_6946702_0 ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003306 478.0
HFD2_k127_6946702_1 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006281 417.0
HFD2_k127_6946702_2 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000051 190.0
HFD2_k127_6946702_3 bifunctional deaminase-reductase domain protein - - - 0.000000000000000000000000000000008786 144.0
HFD2_k127_6977457_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000003243 258.0
HFD2_k127_6977457_1 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000007197 224.0
HFD2_k127_6977457_2 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000005823 118.0
HFD2_k127_6977457_3 - - - - 0.00009613 48.0
HFD2_k127_7006122_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004853 423.0
HFD2_k127_7006122_1 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005487 360.0
HFD2_k127_7006122_10 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.00000006399 64.0
HFD2_k127_7006122_11 PFAM HD domain - - - 0.000001165 58.0
HFD2_k127_7006122_2 - - - - 0.000000000000000000000000000000000000000000000000000001446 201.0
HFD2_k127_7006122_3 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000007666 176.0
HFD2_k127_7006122_4 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.000000000000000000000000000000000000009745 155.0
HFD2_k127_7006122_5 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 GO:0003674,GO:0005488,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 - 0.000000000000000000000000000001479 125.0
HFD2_k127_7006122_6 cellulase activity - - - 0.00000000000000000000000000007517 134.0
HFD2_k127_7006122_8 domain, Protein - - - 0.00000000000000000004416 106.0
HFD2_k127_7006122_9 RES - - - 0.00000000000000000024 96.0
HFD2_k127_7088967_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004251 482.0
HFD2_k127_7088967_1 PFAM phosphate transporter K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 349.0
HFD2_k127_7088967_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004623 273.0
HFD2_k127_7088967_3 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001815 270.0
HFD2_k127_7088967_4 RNHCP domain - - - 0.000000000000000000000000000000000000000000000005998 178.0
HFD2_k127_7088967_5 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000007217 177.0
HFD2_k127_7088967_6 Protein of unknown function DUF47 K02039,K07220 - - 0.000000000000000000000000000000000000000005502 161.0
HFD2_k127_7088967_7 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009378,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360 3.6.4.12 0.0000000000000000000000000000000000002672 147.0
HFD2_k127_7088967_8 - - - - 0.00000001219 66.0
HFD2_k127_7092895_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 466.0
HFD2_k127_7092895_1 Zinc-binding dehydrogenase K00060 - 1.1.1.103 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 362.0
HFD2_k127_7092895_2 HAD-hyrolase-like - - - 0.000000000000000000000000000000000000000002511 162.0
HFD2_k127_7092895_3 periplasmic binding protein LacI transcriptional regulator K01775 - 5.1.1.1 0.00000000000000000000000000000000003216 139.0
HFD2_k127_7092895_4 Metal-dependent hydrolases of the beta-lactamase superfamily III - GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 - 0.00000000000000000004506 97.0
HFD2_k127_7092895_5 Protein of unknown function (DUF3105) - - - 0.000000000002351 78.0
HFD2_k127_7124434_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 7.094e-263 826.0
HFD2_k127_7124434_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002996 589.0
HFD2_k127_7124434_10 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001236 283.0
HFD2_k127_7124434_11 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004724 263.0
HFD2_k127_7124434_12 Acyl CoA acetate 3-ketoacid CoA transferase beta subunit K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000001192 255.0
HFD2_k127_7124434_13 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000004846 256.0
HFD2_k127_7124434_14 ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000009739 206.0
HFD2_k127_7124434_15 Rieske-like [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000000005835 167.0
HFD2_k127_7124434_16 EamA-like transporter family - - - 0.0000000000000000000000000000000000001366 155.0
HFD2_k127_7124434_17 Calcineurin-like phosphoesterase K03547 - - 0.00000000000000000000000000000000002625 152.0
HFD2_k127_7124434_18 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.0000000000000000000000000000000002989 144.0
HFD2_k127_7124434_19 PFAM pfkB family carbohydrate kinase K00852 - 2.7.1.15 0.00000000000000000000000000000001189 138.0
HFD2_k127_7124434_2 Aldehyde dehydrogenase family K00294 - 1.2.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005637 565.0
HFD2_k127_7124434_20 Probable zinc-ribbon domain - - - 0.0000000000000000000000000000003397 129.0
HFD2_k127_7124434_21 Glucose-6-phosphate dehydrogenase subunit - - - 0.000000000000000000000000000002508 135.0
HFD2_k127_7124434_22 - - - - 0.0000000000000000000000000002456 126.0
HFD2_k127_7124434_23 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.0000000000000000000000000004392 115.0
HFD2_k127_7124434_24 AAA domain - - - 0.000000000000000000001414 111.0
HFD2_k127_7124434_25 Transport permease protein K01992 - - 0.000000000003517 69.0
HFD2_k127_7124434_26 Belongs to the universal stress protein A family - - - 0.000000001182 68.0
HFD2_k127_7124434_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00596,K00823 - 2.6.1.19,4.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 527.0
HFD2_k127_7124434_4 Periplasmic binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 519.0
HFD2_k127_7124434_5 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K13810 - 2.2.1.2,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 504.0
HFD2_k127_7124434_6 Coenzyme A transferase K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 389.0
HFD2_k127_7124434_7 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 368.0
HFD2_k127_7124434_8 Belongs to the binding-protein-dependent transport system permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 343.0
HFD2_k127_7124434_9 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 299.0
HFD2_k127_7193221_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 377.0
HFD2_k127_7193221_1 cell redox homeostasis K16089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 306.0
HFD2_k127_7193221_2 methyltransferase K18846 - 2.1.1.180 0.00000000000000000000000000004547 125.0
HFD2_k127_7193221_3 serine threonine protein kinase - - - 0.0000000000000000004092 102.0
HFD2_k127_7193221_4 - K22014 - - 0.0000000001082 65.0
HFD2_k127_7243098_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 481.0
HFD2_k127_7243098_1 Required for chromosome condensation and partitioning K03529 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004556 359.0
HFD2_k127_7243098_10 Belongs to the UPF0109 family K06960 - - 0.000000000000005295 81.0
HFD2_k127_7243098_11 Glyoxal oxidase N-terminus - - - 0.0000000001476 72.0
HFD2_k127_7243098_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002832 276.0
HFD2_k127_7243098_3 Belongs to the RNA methyltransferase TrmD family K00554,K01770 GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000004423 252.0
HFD2_k127_7243098_4 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000001444 243.0
HFD2_k127_7243098_5 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000001042 198.0
HFD2_k127_7243098_6 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000001066 143.0
HFD2_k127_7243098_7 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000498 112.0
HFD2_k127_7243098_8 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000000000000000005223 105.0
HFD2_k127_7243098_9 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000009698 90.0
HFD2_k127_7267068_0 Baseplate J-like protein - - - 1.138e-237 755.0
HFD2_k127_7267068_1 Phage tail sheath C-terminal domain K06907 - - 4.793e-214 678.0
HFD2_k127_7267068_10 PFAM Peptidoglycan-binding - - - 0.0000000000000000000000000000000000000000000001222 181.0
HFD2_k127_7267068_11 T4-like virus tail tube protein gp19 - - - 0.0000000000000000000000000000000000000002259 154.0
HFD2_k127_7267068_12 phage tail protein - - - 0.0000000000000000000000000000005285 126.0
HFD2_k127_7267068_13 Zinc finger domain - - - 0.00000000000000000000003598 115.0
HFD2_k127_7267068_14 - - - - 0.00000000000000004842 81.0
HFD2_k127_7267068_16 Domain of unknown function (DUF4157) - - - 0.000000003388 70.0
HFD2_k127_7267068_17 - - - - 0.00003075 57.0
HFD2_k127_7267068_18 C-terminal tandem repeated domain in type 4 procollagens K06237 GO:0001655,GO:0002009,GO:0002119,GO:0002164,GO:0002791,GO:0002793,GO:0003674,GO:0005198,GO:0005201,GO:0005575,GO:0005576,GO:0005581,GO:0005587,GO:0005604,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0007275,GO:0007399,GO:0007442,GO:0007443,GO:0007517,GO:0007519,GO:0008150,GO:0009653,GO:0009790,GO:0009791,GO:0009792,GO:0009888,GO:0009987,GO:0010720,GO:0010975,GO:0010976,GO:0012505,GO:0014706,GO:0016043,GO:0022008,GO:0030154,GO:0030198,GO:0031012,GO:0031344,GO:0031346,GO:0031974,GO:0032101,GO:0032103,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0032991,GO:0035239,GO:0035295,GO:0043062,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044420,GO:0044421,GO:0044422,GO:0044424,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0045595,GO:0045597,GO:0045664,GO:0045666,GO:0048513,GO:0048518,GO:0048522,GO:0048546,GO:0048565,GO:0048583,GO:0048584,GO:0048598,GO:0048619,GO:0048679,GO:0048680,GO:0048699,GO:0048729,GO:0048731,GO:0048856,GO:0048869,GO:0050708,GO:0050714,GO:0050767,GO:0050769,GO:0050789,GO:0050793,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051094,GO:0051128,GO:0051130,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051960,GO:0051962,GO:0055123,GO:0060284,GO:0060429,GO:0060537,GO:0060538,GO:0060562,GO:0061061,GO:0061326,GO:0061327,GO:0061333,GO:0061525,GO:0062023,GO:0065007,GO:0070013,GO:0070201,GO:0070570,GO:0070572,GO:0071840,GO:0072001,GO:0072002,GO:0080134,GO:0080135,GO:0090087,GO:0098642,GO:0098644,GO:0098645,GO:0098651,GO:0099080,GO:0099081,GO:0120035,GO:1903034,GO:1903036,GO:1903530,GO:1903532,GO:1904951,GO:2000026 - 0.00007138 47.0
HFD2_k127_7267068_2 PFAM AAA ATPase central domain protein - - - 9.632e-213 687.0
HFD2_k127_7267068_3 Rhs element Vgr protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008294 430.0
HFD2_k127_7267068_4 Protein of unknown function (DUF4255) - - - 0.000000000000000000000000000000000000000000000000000000000000000001067 238.0
HFD2_k127_7267068_5 - - - - 0.0000000000000000000000000000000000000000000000000000000005333 204.0
HFD2_k127_7267068_6 Phage tail protein (Tail_P2_I) - - - 0.000000000000000000000000000000000000000000000000000000004183 205.0
HFD2_k127_7267068_7 Domain of unknown function (DUF4157) - - - 0.00000000000000000000000000000000000000000000000000000162 202.0
HFD2_k127_7267068_8 PFAM transcriptional regulator domain protein - - - 0.0000000000000000000000000000000000000000000000000001199 199.0
HFD2_k127_7267068_9 GPW gp25 family protein K06903 - - 0.00000000000000000000000000000000000000000000000002766 183.0
HFD2_k127_728804_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0034220,GO:0040007,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 1.861e-199 638.0
HFD2_k127_728804_1 Multicopper oxidase K22348 - 1.16.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008903 306.0
HFD2_k127_728804_2 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0040007,GO:0042773,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051704,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 0.00000000000000000000000000000000000000000000009376 183.0
HFD2_k127_728804_3 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3 K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000005072 167.0
HFD2_k127_728804_4 periplasmic protein thiol disulfide oxidoreductases, DsbE subfamily K02199 - - 0.00000000000000000000000005935 114.0
HFD2_k127_728804_5 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000000001551 107.0
HFD2_k127_728804_6 PFAM blue (type 1) copper domain protein - - - 0.0000000000798 74.0
HFD2_k127_728804_7 - - - - 0.0003847 46.0
HFD2_k127_7331588_0 Heavy metal translocating P-type atpase K01533,K17686 - 3.6.3.4,3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009557 397.0
HFD2_k127_7331588_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000006424 162.0
HFD2_k127_7331588_2 sporulation protein K06381 - - 0.0000000000000000000000000000000000002321 162.0
HFD2_k127_7331588_3 PFAM thioesterase superfamily protein K07107 - - 0.00000000000000001591 89.0
HFD2_k127_7380380_0 PFAM oxidoreductase, molybdopterin binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003789 261.0
HFD2_k127_7380380_1 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000002989 192.0
HFD2_k127_7380380_2 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000001169 148.0
HFD2_k127_7380380_3 PFAM regulatory protein LuxR - - - 0.00000000000000000000000000000001286 137.0
HFD2_k127_7380380_4 electron transfer activity K05337 - - 0.0001354 53.0
HFD2_k127_7398022_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.876e-230 724.0
HFD2_k127_7398022_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008343 351.0
HFD2_k127_7398022_2 phosphorylase K01243 - 3.2.2.9 0.0000000000000000000000000000000000000000000000000000000000648 219.0
HFD2_k127_7398022_3 TatD related DNase K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.000000000000000000000000000000000000000000002535 175.0
HFD2_k127_7398022_4 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000005731 147.0
HFD2_k127_7398022_5 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.000000000000000000000000000601 117.0
HFD2_k127_7398022_6 PFAM TPR repeat-containing protein - - - 0.0000000000000008192 88.0
HFD2_k127_7398022_7 Acyl-ACP thioesterase - - - 0.000000000008246 75.0
HFD2_k127_7448216_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005231 317.0
HFD2_k127_7448216_1 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 310.0
HFD2_k127_7448216_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 301.0
HFD2_k127_7448216_3 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000001032 198.0
HFD2_k127_7448216_4 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.0000000000000000000000000000000000000000000000001003 183.0
HFD2_k127_7448216_5 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000001079 131.0
HFD2_k127_7448216_6 - - - - 0.00000001954 64.0
HFD2_k127_746568_0 Transketolase, central region K00615 - 2.2.1.1 2.815e-274 864.0
HFD2_k127_746568_1 Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007115 462.0
HFD2_k127_746568_10 Anti-sigma-K factor rskA - - - 0.000001068 59.0
HFD2_k127_746568_2 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000000000000001603 209.0
HFD2_k127_746568_3 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000003422 191.0
HFD2_k127_746568_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000003445 136.0
HFD2_k127_746568_5 Secreted repeat of unknown function - - - 0.000000000000000000000000007056 120.0
HFD2_k127_746568_6 ECF sigma factor K03088 - - 0.00000000000000000000003347 105.0
HFD2_k127_746568_7 Uncharacterized conserved protein (DUF2203) - - - 0.00000000000000001489 87.0
HFD2_k127_746568_8 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0000000001311 62.0
HFD2_k127_746568_9 NlpC/P60 family K19224 - - 0.0000000002388 71.0
HFD2_k127_748445_0 ABC transporter K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 307.0
HFD2_k127_748445_1 Histidine kinase-like ATPases K07673 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004079 286.0
HFD2_k127_748445_2 4Fe-4S dicluster domain K00184 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000003291 245.0
HFD2_k127_748445_3 Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000007995 207.0
HFD2_k127_748445_4 xanthine phosphoribosyltransferase activity K00769,K07101 GO:0000310,GO:0003674,GO:0003824,GO:0004422,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006166,GO:0006177,GO:0006188,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032261,GO:0032263,GO:0032264,GO:0032265,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0043173,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097292,GO:0097293,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.22 0.0000000000000000000000000000000000000000000000102 175.0
HFD2_k127_748445_5 Predicted integral membrane protein (DUF2269) - - - 0.000000000002641 75.0
HFD2_k127_748445_6 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.0000000008683 69.0
HFD2_k127_748445_7 heat shock protein binding - - - 0.0000003066 64.0
HFD2_k127_7721933_0 Fructose-bisphosphate aldolase class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003503 448.0
HFD2_k127_7721933_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 367.0
HFD2_k127_7723641_0 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003392 503.0
HFD2_k127_7723641_1 PFAM UDP-glucose GDP-mannose dehydrogenase family, NAD binding domain K02472,K13015 - 1.1.1.136,1.1.1.336 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004887 404.0
HFD2_k127_7723641_2 Protein of unknown function (DUF354) K09726 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 298.0
HFD2_k127_7723641_3 Iron permease FTR1 family K07243 - - 0.0000000000000000000000000000000000000000000000000000004915 205.0
HFD2_k127_7723641_4 diguanylate cyclase - - - 0.00000000000000000000000000000000001171 151.0
HFD2_k127_7723641_5 transcriptional regulator K03892 - - 0.000000000000000002091 93.0
HFD2_k127_7764564_0 Cell cycle protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000846 355.0
HFD2_k127_7764564_1 PFAM penicillin-binding protein transpeptidase K05364 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008698 282.0
HFD2_k127_7764564_2 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000003227 126.0
HFD2_k127_7764564_3 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000001039 108.0
HFD2_k127_7764564_4 PFAM Forkhead-associated protein - - - 0.00000000000000000000005078 109.0
HFD2_k127_7764564_5 ribonuclease BN - - - 0.00000002244 64.0
HFD2_k127_7787253_0 serine-type endopeptidase activity K01312,K14647 GO:0005575,GO:0005576 3.4.21.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 542.0
HFD2_k127_7787253_1 Flotillin K07192 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002135 271.0
HFD2_k127_7787253_2 Two component transcriptional regulator, LuxR family - - - 0.0000000000000000000000000000000000007189 150.0
HFD2_k127_7787253_3 Transglycosylase associated protein - - - 0.0000000000003939 72.0
HFD2_k127_7787253_4 Membrane protein implicated in regulation of membrane protease activity - - - 0.0000001334 61.0
HFD2_k127_7833300_0 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 561.0
HFD2_k127_7833300_1 Belongs to the amidase family K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 396.0
HFD2_k127_7833300_2 Winged helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006903 374.0
HFD2_k127_7833300_3 Belongs to the long-chain O-acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 371.0
HFD2_k127_7833300_4 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002347 282.0
HFD2_k127_7833300_5 AAA ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001088 260.0
HFD2_k127_7833300_6 PFAM CoA-binding domain protein K06929 - - 0.00000000000000000000000000000000000000000000000000000000000001375 222.0
HFD2_k127_7833300_7 DinB family - - - 0.00000000000000000000000000000000000000002382 158.0
HFD2_k127_7867532_0 Among the AAA ATPases, the YifB protease family belongs to the Helix 2 insert clade K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 416.0
HFD2_k127_7867532_1 PFAM band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 312.0
HFD2_k127_7867532_2 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007902 277.0
HFD2_k127_7867532_3 - - - - 0.0000000000000000000002788 100.0
HFD2_k127_8043717_0 Succinyl-CoA ligase like flavodoxin domain - - - 9.795e-208 670.0
HFD2_k127_8043717_1 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000003561 208.0
HFD2_k127_8043717_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000005019 163.0
HFD2_k127_8076655_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 5.546e-276 873.0
HFD2_k127_8076655_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 4.098e-252 791.0
HFD2_k127_8076655_2 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000899 473.0
HFD2_k127_8076655_3 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 447.0
HFD2_k127_8076655_4 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004034 401.0
HFD2_k127_8076655_5 PFAM methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000005072 226.0
HFD2_k127_8076655_6 Repeat of unknown function (DUF346) - - - 0.000000000000000000000000000000000000000000001878 186.0
HFD2_k127_8076655_7 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000005025 98.0
HFD2_k127_8076655_8 cell adhesion involved in biofilm formation - - - 0.000000000000000008027 98.0
HFD2_k127_8076655_9 Pkd domain containing protein - - - 0.000000000000000008471 93.0
HFD2_k127_8079939_0 Alpha-amylase domain K05343 - 3.2.1.1,5.4.99.16 0.0 1127.0
HFD2_k127_8079939_1 Phosphatidylinositol - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007439 267.0
HFD2_k127_8079939_2 PRC-barrel domain - - - 0.000000000000000000000182 106.0
HFD2_k127_8079939_3 Protein of unknown function (DUF3090) - - - 0.000000000000001198 78.0
HFD2_k127_8079939_4 PRC-barrel domain - - - 0.00000158 58.0
HFD2_k127_8109577_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008033 447.0
HFD2_k127_8109577_1 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 327.0
HFD2_k127_8109577_2 transport system, permease component K01992 - - 0.0000007004 55.0
HFD2_k127_8109577_3 - - - - 0.000004491 55.0
HFD2_k127_8157777_0 Glycoside hydrolase 15-related - - - 8.944e-246 772.0
HFD2_k127_8157777_1 Glycosyl hydrolase family 1 K05350 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 458.0
HFD2_k127_8157777_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 326.0
HFD2_k127_8157777_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004541 285.0
HFD2_k127_8157777_4 SIS domain K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002928 289.0
HFD2_k127_8157777_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K08234 - - 0.0000000000000000000000000000000000000000000000000000000001397 207.0
HFD2_k127_8157777_6 PFAM HhH-GPD family protein - - - 0.000000000000000000000000000000000000000000000000004062 190.0
HFD2_k127_8157777_7 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000006689 159.0
HFD2_k127_8157777_8 Glycosyl hydrolases family 25 K07273 - - 0.000000000000000000000000000000000000000002176 166.0
HFD2_k127_8157777_9 Glycoside hydrolase family 3 K01207 - 3.2.1.52 0.0000000000008216 73.0
HFD2_k127_8175189_0 Glycosyl transferase 4-like domain K08256 - 2.4.1.345 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 335.0
HFD2_k127_8175189_1 Glycosyl transferase K00728 - 2.4.1.109 0.00000000000000000000000000005623 136.0
HFD2_k127_8175189_2 F420H(2)-dependent quinone reductase - - - 0.00000000000000002458 87.0
HFD2_k127_8196294_0 PFAM peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 464.0
HFD2_k127_8196294_1 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000002168 135.0
HFD2_k127_8196294_2 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000001717 121.0
HFD2_k127_8196294_3 Protein of unknown function (DUF971) - - - 0.0000000000000000000000003532 109.0
HFD2_k127_8196294_4 D-alanyl-D-alanine carboxypeptidase K07260 - 3.4.17.14 0.00000000000000000003362 105.0
HFD2_k127_8196294_5 transcriptional regulator - - - 0.000000000002403 72.0
HFD2_k127_8196294_6 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000003225 67.0
HFD2_k127_8229730_0 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 7.737e-235 736.0
HFD2_k127_8229730_1 Aldehyde dehydrogenase family K00128 - 1.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004413 377.0
HFD2_k127_8229730_2 Beta-ketoacyl synthase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 334.0
HFD2_k127_8229730_3 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000005717 156.0
HFD2_k127_8229730_4 geranylgeranyl reductase activity K21401 - 1.3.99.38 0.000000000000000000000000000000000000003355 162.0
HFD2_k127_8229730_5 negative regulation of translational initiation K05554,K15885 - - 0.00000000000000000002178 99.0
HFD2_k127_8278682_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 446.0
HFD2_k127_8278682_1 E1-E2 ATPase K01533 - 3.6.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 349.0
HFD2_k127_8278682_10 Heavy metal translocating P-type atpase K01533,K17686 - 3.6.3.4,3.6.3.54 0.00000131 59.0
HFD2_k127_8278682_2 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003461 261.0
HFD2_k127_8278682_3 histidine kinase HAMP region domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000706 256.0
HFD2_k127_8278682_4 DinB superfamily - - - 0.00000000000000000000000000000000000000005761 171.0
HFD2_k127_8278682_5 pyridine nucleotide-disulphide oxidoreductase K00529 - 1.18.1.3 0.0000000000000000000000000000000000000002977 152.0
HFD2_k127_8278682_6 PFAM cytochrome c biogenesis protein, transmembrane region - - - 0.000000000000000000000000000387 126.0
HFD2_k127_8278682_7 PFAM blue (type 1) copper domain protein - - - 0.00000000000000002748 88.0
HFD2_k127_8278682_8 Short C-terminal domain K08982 - - 0.0000007855 53.0
HFD2_k127_8278682_9 heavy metal translocating P-type ATPase K17686,K19597 - 3.6.3.54 0.0000009283 61.0
HFD2_k127_8281793_0 PFAM Rieske 2Fe-2S domain protein K00479,K00499,K05708 - 1.14.12.19,1.14.15.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004502 499.0
HFD2_k127_8281793_1 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000007068 235.0
HFD2_k127_8281793_2 Cytidylate kinase-like family K00760 - 2.4.2.8 0.000000000000000000000000000000000001848 146.0
HFD2_k127_8281793_3 Metal-sensitive transcriptional repressor K21600 - - 0.000000000000000000001072 98.0
HFD2_k127_8281793_4 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.000000000000000003131 95.0
HFD2_k127_8335927_0 ABC-type Fe3 transport system permease component K02011,K02063 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002162 554.0
HFD2_k127_8335927_1 NAD(P) transhydrogenase beta subunit K00325 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 521.0
HFD2_k127_8335927_10 PFAM LmbE family protein - - - 0.000000000000000000000000000000000000000000000000009006 190.0
HFD2_k127_8335927_11 Redoxin K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000003904 182.0
HFD2_k127_8335927_12 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.00000000000000000000000000000000000000000002215 170.0
HFD2_k127_8335927_13 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000003139 175.0
HFD2_k127_8335927_14 PFAM Thiamin pyrophosphokinase, catalytic region K00949 - 2.7.6.2 0.000000000000000000000000000000000000002632 159.0
HFD2_k127_8335927_15 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000001205 163.0
HFD2_k127_8335927_16 NADP transhydrogenase K00324 - 1.6.1.2 0.0000000000000000000000000000000000006671 142.0
HFD2_k127_8335927_17 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.0000000000000000000000000000000001812 153.0
HFD2_k127_8335927_18 Aminoacyl-tRNA editing domain - - - 0.0000000000000000000000000000000192 135.0
HFD2_k127_8335927_19 Rieske 2Fe-2S - - - 0.000000000000000000000002664 111.0
HFD2_k127_8335927_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 459.0
HFD2_k127_8335927_21 FAD linked oxidases, C-terminal domain K00104 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 1.1.3.15 0.0000000000000000002881 94.0
HFD2_k127_8335927_22 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000257 69.0
HFD2_k127_8335927_24 Peptidase family M23 K21472 - - 0.000000002502 69.0
HFD2_k127_8335927_25 Major Facilitator - - - 0.000000005034 68.0
HFD2_k127_8335927_26 Cytochrome c K00406,K03889,K17222,K19713 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005507,GO:0005515,GO:0005575,GO:0005623,GO:0006091,GO:0006464,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0016667,GO:0016669,GO:0016740,GO:0016782,GO:0016783,GO:0018192,GO:0018193,GO:0018198,GO:0018307,GO:0019417,GO:0019538,GO:0020037,GO:0022900,GO:0036211,GO:0042597,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046872,GO:0046906,GO:0046914,GO:0046982,GO:0046983,GO:0048037,GO:0055114,GO:0071704,GO:0097159,GO:0098822,GO:1901363,GO:1901564 1.8.2.2 0.00008163 55.0
HFD2_k127_8335927_3 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005124 453.0
HFD2_k127_8335927_4 PFAM alanine dehydrogenase PNT domain protein K00324 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003664 406.0
HFD2_k127_8335927_5 Bacterial extracellular solute-binding protein K02064 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 341.0
HFD2_k127_8335927_6 Belongs to the ABC transporter superfamily K02052,K02062 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 335.0
HFD2_k127_8335927_7 Cytochrome b/b6/petB K03891 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 324.0
HFD2_k127_8335927_8 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001384 251.0
HFD2_k127_8335927_9 WYL domain K07012,K13572 - - 0.000000000000000000000000000000000000000000000000000000000004294 227.0
HFD2_k127_836761_0 involved in signal transduction (via phosphorylation) involved in transcriptional regulatory mechanism and in the regulation of secondary metabolites catalytic activity ATP a protein ADP a phosphoprotein K08282 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005293 333.0
HFD2_k127_836761_1 Two component transcriptional regulator, winged helix family K02483,K07662 - - 0.0000000000000000000000000000000000000000000000000000000000009754 221.0
HFD2_k127_836761_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000373 206.0
HFD2_k127_836761_3 FMN binding - - - 0.00000000000000003751 89.0
HFD2_k127_836761_4 - - - - 0.00000005806 58.0
HFD2_k127_836761_5 - - - - 0.0002749 50.0
HFD2_k127_8376557_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004499 358.0
HFD2_k127_8376557_1 Provides the (R)-glutamate required for cell wall biosynthesis K01776,K02428 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 3.6.1.66,5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000009868 240.0
HFD2_k127_8376557_2 Zincin-like metallopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002992 246.0
HFD2_k127_8376557_3 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region - - - 0.0000000000000000000000000000000000000000000000000000000000000000006108 241.0
HFD2_k127_8376557_4 NUBPL iron-transfer P-loop NTPase K02282 - - 0.000000000000000000000000007689 124.0
HFD2_k127_8376557_5 PFAM PfkB domain protein - - - 0.00000000000004718 81.0
HFD2_k127_8376557_6 methyltransferase - - - 0.000001897 57.0
HFD2_k127_8380048_0 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 528.0
HFD2_k127_8380048_1 Putative esterase K07017 - - 0.000000000000000000000000000000000000000000000000000000000000000001183 238.0
HFD2_k127_8380048_2 catechol 2,3-dioxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000001074 212.0
HFD2_k127_8380048_3 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000001945 204.0
HFD2_k127_8380048_4 Inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000000000000000001255 167.0
HFD2_k127_8457265_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004101 589.0
HFD2_k127_8457265_1 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000006113 200.0
HFD2_k127_8457265_2 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000007943 194.0
HFD2_k127_8457265_3 CDP-alcohol phosphatidyltransferase K17884 - 2.7.8.39 0.000000000000000000000001623 111.0
HFD2_k127_8457265_4 DNA-binding transcription factor activity K03892 - - 0.000000000001214 72.0
HFD2_k127_8474852_0 decarboxylase K01593 - 4.1.1.105,4.1.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 471.0
HFD2_k127_8474852_1 AAA domain, putative AbiEii toxin, Type IV TA system K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007237 455.0
HFD2_k127_8474852_10 PFAM histidine triad (HIT) protein K02503 - - 0.000000000000000000000000000000000000001081 152.0
HFD2_k127_8474852_11 UbiA prenyltransferase family K02548 - 2.5.1.74 0.0000000000000000000000000000000000000037 164.0
HFD2_k127_8474852_12 methyltransferase - - - 0.00000000000000000000000000000001247 129.0
HFD2_k127_8474852_13 Yqey-like protein K09117 - - 0.00000000000000000000000000000001768 133.0
HFD2_k127_8474852_14 Protein of unknown function (DUF1684) K09164 - - 0.000000000000000000000000000002061 130.0
HFD2_k127_8474852_15 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000006699 96.0
HFD2_k127_8474852_16 Ribosomal protein S21 K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000001867 83.0
HFD2_k127_8474852_17 coenzyme F420 binding - - - 0.0000000001224 73.0
HFD2_k127_8474852_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008844 368.0
HFD2_k127_8474852_3 7TM-HD extracellular K07037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 376.0
HFD2_k127_8474852_4 Winged helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 315.0
HFD2_k127_8474852_5 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 315.0
HFD2_k127_8474852_6 Transport permease protein K09694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006987 297.0
HFD2_k127_8474852_7 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001103 265.0
HFD2_k127_8474852_8 Transport permease protein K09694 - - 0.0000000000000000000000000000000000000000000000000000000000002028 220.0
HFD2_k127_8474852_9 L11 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000002129 213.0
HFD2_k127_8528760_0 glutamine synthetase K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006265 604.0
HFD2_k127_8528760_1 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01761 - 4.4.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003518 325.0
HFD2_k127_8528760_2 cytochrome c biogenesis protein K07399 - - 0.000000000000000000000000000000000000000002065 179.0
HFD2_k127_8528760_3 phosphatase activity K07025,K20866 - 3.1.3.10 0.000000008424 66.0
HFD2_k127_8528760_4 positive regulation of transcription, DNA-templated K09684 - - 0.000001189 61.0
HFD2_k127_8528760_5 PucR C-terminal helix-turn-helix domain - - - 0.000002745 60.0
HFD2_k127_8540443_0 ketone body catabolic process K01026 - 2.8.3.1 6.914e-206 660.0
HFD2_k127_8540443_1 Belongs to the aldehyde dehydrogenase family K00141 - 1.2.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 449.0
HFD2_k127_8540443_2 Periplasmic binding protein LacI transcriptional regulator K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009342 258.0
HFD2_k127_8540443_3 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001273 246.0
HFD2_k127_8540443_4 Short-chain dehydrogenase reductase sdr K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000006725 238.0
HFD2_k127_8540443_5 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) - - - 0.0000000000000000000000000000000000000000000000000000000000000001064 234.0
HFD2_k127_8540443_6 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000522 226.0
HFD2_k127_8540443_7 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000002967 177.0
HFD2_k127_8540443_8 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000001888 179.0
HFD2_k127_8540443_9 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) - - - 0.00000000000000000000000000000000008276 145.0
HFD2_k127_8566606_0 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003512 507.0
HFD2_k127_8566606_1 transferase activity, transferring glycosyl groups K09118,K13693,K21349 - 2.4.1.266,2.4.1.268 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 447.0
HFD2_k127_8566606_2 III protein, CoA-transferase family K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 383.0
HFD2_k127_8566606_3 Belongs to the glycerate kinase type-1 family K00865 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001147 287.0
HFD2_k127_8566606_4 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000001139 204.0
HFD2_k127_8566606_5 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000005005 190.0
HFD2_k127_8566606_6 Domain of unknown function (DUF4157) - - - 0.000000002022 70.0
HFD2_k127_8574835_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 1.271e-319 1000.0
HFD2_k127_8574835_1 COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase - - - 0.000000000000000000000000000000000000000000000000005391 194.0
HFD2_k127_8574835_2 Competence protein K02238 - - 0.000000000000000000000000000001952 137.0
HFD2_k127_8574835_3 ComEA protein K02237 - - 0.0000000000000000000000007538 115.0
HFD2_k127_8574835_4 Putative stress-induced transcription regulator - - - 0.0000000000000000000008608 106.0
HFD2_k127_8574835_5 Belongs to the UPF0271 (lamB) family K07160 - - 0.000000000001598 69.0
HFD2_k127_8611796_0 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 323.0
HFD2_k127_8611796_1 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001159 259.0
HFD2_k127_8611796_2 Putative Phosphatase - - - 0.0000000000000000000000001573 119.0
HFD2_k127_8611796_3 Peptidoglycan-binding lysin domain - - - 0.00000000000000509 88.0
HFD2_k127_8611796_4 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.000002754 58.0
HFD2_k127_8611796_5 - - - - 0.0000249 54.0
HFD2_k127_8615622_0 Carbamoyl-phosphate synthetase large chain domain protein K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005884 519.0
HFD2_k127_8615622_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 447.0
HFD2_k127_8615622_10 Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC - - - 0.000000000000000000000000000000000000000000000000000000000002442 225.0
HFD2_k127_8615622_11 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000008129 160.0
HFD2_k127_8615622_12 7TMR-DISM extracellular 2 - - - 0.000000000000000000000000000001264 136.0
HFD2_k127_8615622_13 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000001136 119.0
HFD2_k127_8615622_14 acetylesterase activity - - - 0.00000000000000000000000002801 121.0
HFD2_k127_8615622_15 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000004181 100.0
HFD2_k127_8615622_16 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0008459 49.0
HFD2_k127_8615622_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003685 360.0
HFD2_k127_8615622_3 Sulfotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007121 347.0
HFD2_k127_8615622_4 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K00991,K21681 - 1.1.1.405,2.7.7.40,2.7.7.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 323.0
HFD2_k127_8615622_5 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000814 308.0
HFD2_k127_8615622_6 KR domain K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003555 283.0
HFD2_k127_8615622_7 Helix-hairpin-helix DNA-binding, class 1 K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001462 279.0
HFD2_k127_8615622_8 Catalyzes the synthesis of activated sulfate K00958 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000004775 241.0
HFD2_k127_8615622_9 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000006751 228.0
HFD2_k127_8680663_0 ABC transporter, phosphonate, periplasmic substrate-binding protein K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 396.0
HFD2_k127_8680663_1 Von Willebrand factor type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 387.0
HFD2_k127_8680663_2 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 338.0
HFD2_k127_8680663_3 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 324.0
HFD2_k127_8680663_4 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000001384 177.0
HFD2_k127_8680663_5 Peptidase family M28 K19702 - 3.4.11.24 0.00000000000000003362 84.0
HFD2_k127_8700149_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004836 591.0
HFD2_k127_8700149_1 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000615 193.0
HFD2_k127_8700149_2 Glycosyltransferase family 20 K00697,K16055 - 2.4.1.15,2.4.1.347,3.1.3.12 0.0000000000000000000000000000000000000000055 164.0
HFD2_k127_8700149_3 cellulase activity - - - 0.00000000000000000000001513 117.0
HFD2_k127_8700149_4 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000001796 106.0
HFD2_k127_8700149_5 Thioredoxin-like K06196 - - 0.0000000000000000000002406 106.0
HFD2_k127_8700149_6 Glycosyl hydrolase family 65, C-terminal domain K01087,K01194 GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0030312,GO:0044464,GO:0071944 3.1.3.12,3.2.1.28 0.000000000000000000001102 111.0
HFD2_k127_8700149_7 DNA-binding transcription factor activity K03892 - - 0.0000000000002097 75.0
HFD2_k127_8708529_0 PFAM Prolyl oligopeptidase family - - - 5.895e-202 651.0
HFD2_k127_8708529_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 406.0
HFD2_k127_8708529_2 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.000000000000000000000000000000000000000000000000000000002492 226.0
HFD2_k127_914265_0 Flavin containing amine oxidoreductase K00274 - 1.4.3.4 1.156e-206 657.0
HFD2_k127_914265_1 Flavin containing amine oxidoreductase K00274 - 1.4.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 587.0
HFD2_k127_914265_2 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000006582 280.0
HFD2_k127_914265_3 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000006315 240.0
HFD2_k127_914265_4 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000001346 223.0
HFD2_k127_951161_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005973 556.0
HFD2_k127_951161_1 tRNA synthetases class I (K) K04566 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 432.0
HFD2_k127_951161_10 Regulates arginine biosynthesis genes K03402 - - 0.00000000000000000000000004851 113.0
HFD2_k127_951161_11 Protein of unknown function (DUF2752) - - - 0.0000000000006809 78.0
HFD2_k127_951161_12 - - - - 0.00000005989 60.0
HFD2_k127_951161_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 423.0
HFD2_k127_951161_3 PFAM Rhomboid family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000312 254.0
HFD2_k127_951161_4 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000006409 228.0
HFD2_k127_951161_5 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000002152 174.0
HFD2_k127_951161_6 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000002274 157.0
HFD2_k127_951161_7 Zn-dependent dipeptidase, microsomal dipeptidase - - - 0.00000000000000000000000000000000000723 150.0
HFD2_k127_951161_8 TM2 domain - - - 0.00000000000000000000000000000000009459 137.0
HFD2_k127_951161_9 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.00000000000000000000000000003653 122.0
HFD2_k127_955483_0 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 287.0
HFD2_k127_955483_1 WD40-like Beta Propeller Repeat K03641 - - 0.000000000000000001599 100.0
HFD2_k127_955483_2 Signal transduction histidine kinase - - - 0.0000000000000001307 92.0
HFD2_k127_955483_3 L-asparaginase II - - - 0.000000000001542 72.0
HFD2_k127_985572_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008389 447.0
HFD2_k127_985572_1 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0046167,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901576 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006816 293.0
HFD2_k127_985572_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000002126 222.0
HFD2_k127_985572_3 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000001515 177.0
HFD2_k127_985572_5 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000009175 145.0
HFD2_k127_985572_6 Transcriptional regulator K07729 - - 0.0000000000000000002748 89.0
HFD2_k127_985572_7 Septum formation - - - 0.00000000000004372 81.0