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Overview

ID MAG01656
Name HFD2_bin.48
Sample SMP0044
Taxonomy
Kingdom Bacteria
Phylum Myxococcota
Class Myxococcia
Order Myxococcales
Family Anaeromyxobacteraceae
Genus DASTPH01
Species
Assembly information
Completeness (%) 81.07
Contamination (%) 3.89
GC content (%) 76.0
N50 (bp) 14,660
Genome size (bp) 2,987,421

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2585

Gene name Description KEGG GOs EC E-value Score Sequence
HFD2_k127_1006277_0 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005075 391.0
HFD2_k127_1006277_1 Nucleotidyl transferase K00966,K16881 - 2.7.7.13,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008639 366.0
HFD2_k127_1006277_2 Diacylglycerol kinase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005028 352.0
HFD2_k127_1006277_3 Protein serine threonine phosphatase K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007742 357.0
HFD2_k127_1022918_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0 1057.0
HFD2_k127_1022918_1 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 456.0
HFD2_k127_1022918_3 - - - - 0.0000000000000000000006816 100.0
HFD2_k127_1078008_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 436.0
HFD2_k127_1078008_1 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 404.0
HFD2_k127_1078008_2 RNase_H superfamily K07502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003484 385.0
HFD2_k127_1078068_0 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 449.0
HFD2_k127_1078068_1 Protein of unknown function (DUF1232) - - - 0.0000000000000000000000000003996 123.0
HFD2_k127_1078767_2 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000001959 94.0
HFD2_k127_110034_0 FAD dependent oxidoreductase - - - 1.305e-197 626.0
HFD2_k127_110034_1 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007448 369.0
HFD2_k127_110034_2 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 295.0
HFD2_k127_110034_3 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000002931 244.0
HFD2_k127_110034_4 peptidase activity, acting on L-amino acid peptides - - - 0.000000000000000000000000000000000001915 156.0
HFD2_k127_110034_5 Hexapeptide repeat of succinyl-transferase - - - 0.000000000000000000000000000000002322 139.0
HFD2_k127_110034_6 - - - - 0.0000000000000000000000000001597 129.0
HFD2_k127_1100596_0 Biopterin-dependent aromatic amino acid hydroxylase K00500 - 1.14.16.1 1.865e-208 664.0
HFD2_k127_1100596_1 Protein of unknown function (DUF1015) - - - 9.879e-196 618.0
HFD2_k127_1100596_10 ubiE/COQ5 methyltransferase family K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000001109 228.0
HFD2_k127_1100596_11 gamma-glutamylcyclotransferase activity - - - 0.0000000000000000000000000000000000000000000000000000002811 198.0
HFD2_k127_1100596_12 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000002622 192.0
HFD2_k127_1100596_13 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000007475 177.0
HFD2_k127_1100596_14 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000004489 162.0
HFD2_k127_1100596_15 belongs to the thioredoxin family K00384,K03671 - 1.8.1.9 0.0000000000000000000000000000000000009226 143.0
HFD2_k127_1100596_16 Domain of unknown function (DUF1992) - - - 0.00000000000000000000000000000009975 131.0
HFD2_k127_1100596_17 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.00000000000000000008954 95.0
HFD2_k127_1100596_18 Alpha beta hydrolase - - - 0.000000000000000006845 93.0
HFD2_k127_1100596_19 PFAM Hemerythrin HHE cation binding domain protein K07216 - - 0.0000000000000001144 86.0
HFD2_k127_1100596_2 radical SAM K06871 - - 3.954e-194 617.0
HFD2_k127_1100596_3 Domain of unknown function (DUF3413) K07014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 575.0
HFD2_k127_1100596_4 Pyridoxal-phosphate dependent enzyme K01697,K01738 - 2.5.1.47,4.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007648 560.0
HFD2_k127_1100596_5 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 446.0
HFD2_k127_1100596_6 cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 440.0
HFD2_k127_1100596_7 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 378.0
HFD2_k127_1100596_8 cell septum assembly - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 302.0
HFD2_k127_1100596_9 TIGRFAM cytochrome C family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007788 303.0
HFD2_k127_1137172_0 CoA binding domain K09181 - - 2.737e-317 1005.0
HFD2_k127_1137172_1 PFAM thiamine pyrophosphate protein domain protein TPP-binding K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023 514.0
HFD2_k127_1137172_2 Alpha beta hydrolase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 312.0
HFD2_k127_1137172_3 UbiA prenyltransferase family K02548 - 2.5.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 297.0
HFD2_k127_1137172_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008791 275.0
HFD2_k127_1137172_5 Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003459 253.0
HFD2_k127_1137172_6 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000532 176.0
HFD2_k127_1137172_7 PFAM CBS domain containing protein K04767 - - 0.00000000000000000000000000000216 131.0
HFD2_k127_1137172_8 transcriptional regulator - - - 0.00000000000000009756 88.0
HFD2_k127_114416_0 signal peptide peptidase SppA, 36K type K04773 - - 1.395e-219 713.0
HFD2_k127_114416_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004038 617.0
HFD2_k127_114416_2 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 597.0
HFD2_k127_114416_3 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.0000000000000315 72.0
HFD2_k127_118045_0 Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007796 266.0
HFD2_k127_118045_1 Glutathione S-transferase K00799 GO:0000302,GO:0003674,GO:0003824,GO:0004364,GO:0006950,GO:0006979,GO:0008150,GO:0009636,GO:0010035,GO:0016740,GO:0016765,GO:0042221,GO:0042493,GO:0042542,GO:0046677,GO:0050896,GO:1901700 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000003005 235.0
HFD2_k127_118251_0 Molydopterin dinucleotide binding domain - - - 3.25e-287 915.0
HFD2_k127_118251_1 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 2.758e-264 833.0
HFD2_k127_118251_2 Cytochrome c, mono- and diheme variants - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 621.0
HFD2_k127_118251_3 heat shock protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005079 644.0
HFD2_k127_118251_4 2Fe-2S iron-sulfur cluster binding domain K00491,K21324 - 1.14.14.47 0.00000000000000000000000000000000000000000000000000000000000005496 217.0
HFD2_k127_118251_5 RNA polymerase K03088 - - 0.0000000000000000000000000000000000000000000000000000004938 205.0
HFD2_k127_118251_6 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000000000000005176 195.0
HFD2_k127_118251_7 LysM domain - - - 0.0000000000000000000000000000000000000000000000000001102 194.0
HFD2_k127_118251_8 - - - - 0.000000000000000000000000000000001319 137.0
HFD2_k127_118251_9 YceI-like domain - - - 0.000000000000003387 86.0
HFD2_k127_1199651_0 PFAM Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009998 411.0
HFD2_k127_1199651_1 Uncharacterised protein family UPF0066 K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000001957 209.0
HFD2_k127_1201652_0 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.0 1204.0
HFD2_k127_1201652_1 Tetratricopeptide repeat - - - 4.26e-292 979.0
HFD2_k127_1201652_10 OsmC-like protein - - - 0.00000000000000000000000000000000000003656 163.0
HFD2_k127_1201652_2 Carboxyl transferase domain K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 2.008e-273 848.0
HFD2_k127_1201652_3 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003457 562.0
HFD2_k127_1201652_4 nuclear chromosome segregation K02557,K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 513.0
HFD2_k127_1201652_5 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 475.0
HFD2_k127_1201652_6 Methylates ribosomal protein L11 K02687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005637 337.0
HFD2_k127_1201652_7 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000000000000000000000000000000000000002212 280.0
HFD2_k127_1201652_9 RDD family - - - 0.00000000000000000000000000000000000000000001823 175.0
HFD2_k127_1201834_0 Thiolase, C-terminal domain K00626,K07508 - 2.3.1.16,2.3.1.9 4.831e-204 640.0
HFD2_k127_1201834_1 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008071 407.0
HFD2_k127_1201834_2 Sir2 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006316 414.0
HFD2_k127_1201834_3 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001665 274.0
HFD2_k127_1201834_4 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000003719 229.0
HFD2_k127_1201834_5 Methyl-transferase K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000002016 181.0
HFD2_k127_1201834_6 PDZ DHR GLGF domain protein K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000008664 162.0
HFD2_k127_1201834_7 Domain of unknown function (DUF1844) - - - 0.0000000000000000000000000000001183 131.0
HFD2_k127_1201834_8 Eukaryotic integral membrane protein (DUF1751) - - - 0.000000000000000000000000000005787 128.0
HFD2_k127_1240864_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0 1306.0
HFD2_k127_1240864_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 2.81e-254 812.0
HFD2_k127_1240864_2 pfam abc1 K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006635 611.0
HFD2_k127_1240864_3 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005217 566.0
HFD2_k127_1240864_4 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 567.0
HFD2_k127_1240864_5 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005707 434.0
HFD2_k127_1240864_6 Belongs to the SUA5 family K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 350.0
HFD2_k127_1240864_7 PFAM ThiJ PfpI domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 288.0
HFD2_k127_1240864_8 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002126 262.0
HFD2_k127_1240864_9 Class III cytochrome C family - - - 0.00000000000001783 79.0
HFD2_k127_1303401_0 NAD-dependent epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 519.0
HFD2_k127_1303401_1 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 474.0
HFD2_k127_1303401_10 Ribbon-helix-helix domain - - - 0.0000000000000000000000000004554 114.0
HFD2_k127_1303401_11 - K00712 - 2.4.1.52 0.00000000000000000000002532 107.0
HFD2_k127_1303401_2 A G-specific K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 398.0
HFD2_k127_1303401_3 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 367.0
HFD2_k127_1303401_4 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009227 340.0
HFD2_k127_1303401_5 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 295.0
HFD2_k127_1303401_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002898 282.0
HFD2_k127_1303401_7 PFAM thiamine pyrophosphate protein domain protein TPP-binding K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000001305 253.0
HFD2_k127_1303401_8 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007284 265.0
HFD2_k127_1303401_9 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000000000000000000000000009473 229.0
HFD2_k127_131363_0 PFAM oxidoreductase FAD NAD(P)-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 316.0
HFD2_k127_131363_1 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001102 287.0
HFD2_k127_131363_2 HupE / UreJ protein - - - 0.0000000000000000000000000000000000000000000000000000006217 205.0
HFD2_k127_131363_3 Peptidase family M48 - - - 0.0000000000000000000005213 112.0
HFD2_k127_131363_4 - - - - 0.0000000000000003665 85.0
HFD2_k127_1440429_0 NUBPL iron-transfer P-loop NTPase K04562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 511.0
HFD2_k127_1440429_1 HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 355.0
HFD2_k127_1440429_2 Transglycosylase SLT domain K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003885 355.0
HFD2_k127_1440429_3 sequence-specific DNA binding - - - 0.00000000000000008399 93.0
HFD2_k127_1471954_0 Belongs to the peptidase M50B family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005519 442.0
HFD2_k127_1471954_1 Domain of unknown function (DUF1731) K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 377.0
HFD2_k127_1471954_2 Semialdehyde dehydrogenase, NAD binding domain K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 322.0
HFD2_k127_1504375_0 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 449.0
HFD2_k127_1504375_1 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 431.0
HFD2_k127_1504375_10 Peptidase family M50 K11749 - - 0.00000000000000000001877 91.0
HFD2_k127_1504375_11 iron ion homeostasis - - - 0.00000000002995 70.0
HFD2_k127_1504375_13 LysM domain - - - 0.0007048 51.0
HFD2_k127_1504375_2 NAD(P)-binding Rossmann-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007246 429.0
HFD2_k127_1504375_3 NAD(P)-binding Rossmann-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 419.0
HFD2_k127_1504375_4 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003585 301.0
HFD2_k127_1504375_5 HAD-hyrolase-like K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000001974 264.0
HFD2_k127_1504375_6 DNA-templated transcription, initiation K03088,K11333 - 1.3.7.14,1.3.7.15 0.0000000000000000000000000000000000000000000000000002591 200.0
HFD2_k127_1504375_7 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.00000000000000000000000000000000000000000000002241 189.0
HFD2_k127_1504375_9 Response regulator, receiver - - - 0.0000000000000000000000000000000000005091 142.0
HFD2_k127_153123_0 May be involved in recombinational repair of damaged DNA K03631 - - 1.628e-230 728.0
HFD2_k127_153123_1 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004918 494.0
HFD2_k127_153123_2 peptidase M24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 445.0
HFD2_k127_153123_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 383.0
HFD2_k127_153123_4 protein phosphatase 2C domain protein K01090,K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009049 374.0
HFD2_k127_153123_5 Bacterial capsule synthesis protein PGA_cap - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005954 319.0
HFD2_k127_153123_6 cysteine-type peptidase activity K21471,K21473,K21687 - - 0.0000000000000000000000000000000000005367 150.0
HFD2_k127_153123_7 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000682 68.0
HFD2_k127_1540830_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 2.764e-208 655.0
HFD2_k127_1540830_1 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 569.0
HFD2_k127_1540830_2 TIGRFAM cytochrome C family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 541.0
HFD2_k127_1540830_3 Serine Threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 456.0
HFD2_k127_1540830_4 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000006457 151.0
HFD2_k127_1540830_5 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0000000000000000001766 91.0
HFD2_k127_16065_0 Prolyl oligopeptidase family - - - 9.125e-270 858.0
HFD2_k127_16065_1 homoserine dehydrogenase - - - 3.249e-201 652.0
HFD2_k127_16065_10 endonuclease activity K07451 - - 0.0000000000005553 73.0
HFD2_k127_16065_2 TGS domain K06944 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 459.0
HFD2_k127_16065_3 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009641 430.0
HFD2_k127_16065_4 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 308.0
HFD2_k127_16065_5 Late embryogenesis abundant protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002014 259.0
HFD2_k127_16065_6 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000613 240.0
HFD2_k127_16065_7 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000008248 225.0
HFD2_k127_16065_8 - - - - 0.00000000000000000000000000000000000000000000000004871 199.0
HFD2_k127_1779744_0 cellulase activity - - - 4.647e-267 863.0
HFD2_k127_1779744_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 455.0
HFD2_k127_1779744_2 Stage II sporulation D domain protein K06381 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001245 299.0
HFD2_k127_1779744_4 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000006336 135.0
HFD2_k127_1779744_5 FG-GAP repeat protein K18197 - 4.2.2.23 0.000000000000009853 89.0
HFD2_k127_1779744_6 endonuclease activity K07451 - - 0.00009791 50.0
HFD2_k127_1780903_0 Protein-disulfide isomerase - - - 1.698e-254 803.0
HFD2_k127_1780903_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 2.797e-243 760.0
HFD2_k127_1780903_10 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000000000000000000000001169 225.0
HFD2_k127_1780903_11 DNA helicase K03654 - 3.6.4.12 0.000000000000000000000000000000000000000000000004289 191.0
HFD2_k127_1780903_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 1.961e-206 661.0
HFD2_k127_1780903_3 Peptidase family M28 - - - 2.278e-198 664.0
HFD2_k127_1780903_4 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 525.0
HFD2_k127_1780903_5 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003236 326.0
HFD2_k127_1780903_6 Peptidase C26 K01658,K01664 - 2.6.1.85,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 329.0
HFD2_k127_1780903_7 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003995 325.0
HFD2_k127_1780903_8 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 313.0
HFD2_k127_1780903_9 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000002993 268.0
HFD2_k127_1787851_0 ATP-binding region ATPase domain protein K03407,K13490 - 2.7.13.3 1.4e-322 1004.0
HFD2_k127_1787851_1 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 3.935e-199 654.0
HFD2_k127_1787851_2 Methyl-accepting chemotaxis protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004871 564.0
HFD2_k127_1787851_3 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004186 476.0
HFD2_k127_1787851_4 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 341.0
HFD2_k127_1787851_5 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000000000000000000000000000000000000003922 232.0
HFD2_k127_1787851_6 Response regulator receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000004586 232.0
HFD2_k127_1794651_0 PFAM peptidase U62 modulator of DNA gyrase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006677 589.0
HFD2_k127_1794651_1 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009263 314.0
HFD2_k127_1794651_2 PFAM Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006898 250.0
HFD2_k127_1794651_3 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000002797 139.0
HFD2_k127_1805444_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 1.467e-223 709.0
HFD2_k127_1805444_1 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 536.0
HFD2_k127_1842771_0 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840,K15778 - 5.4.2.2,5.4.2.8 1.543e-224 723.0
HFD2_k127_1842771_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 2.545e-208 652.0
HFD2_k127_1842771_10 MotA TolQ ExbB proton channel K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004498 266.0
HFD2_k127_1842771_11 FtsZ-dependent cytokinesis K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001217 247.0
HFD2_k127_1842771_13 NUDIX domain - - - 0.00000000000000000000000000000000000000000000000000000001558 224.0
HFD2_k127_1842771_14 energy transducer activity K03832 - - 0.00000000000000000000000000000000000000000000000000001483 203.0
HFD2_k127_1842771_15 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000003059 180.0
HFD2_k127_1842771_16 Biopolymer transport protein ExbD TolR K03559 - - 0.000000000000000000000000000000000000000000002635 169.0
HFD2_k127_1842771_17 Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000004465 166.0
HFD2_k127_1842771_18 Bacterial membrane protein, YfhO - - - 0.000000000000000000000000000000000004071 158.0
HFD2_k127_1842771_19 Protein of unknown function (DUF2846) - - - 0.0000000000000000000000138 107.0
HFD2_k127_1842771_2 Domain of unknown function (DUF814) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 543.0
HFD2_k127_1842771_3 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 526.0
HFD2_k127_1842771_4 Mannose-6-phosphate isomerase K00971 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006726 534.0
HFD2_k127_1842771_5 Peptidase dimerisation domain K01295 - 3.4.17.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 465.0
HFD2_k127_1842771_6 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004584 420.0
HFD2_k127_1842771_7 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004447 394.0
HFD2_k127_1842771_8 PFAM ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 374.0
HFD2_k127_1842771_9 Protein of unknown function DUF45 K07043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 313.0
HFD2_k127_1854697_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1448.0
HFD2_k127_1854697_1 Transcriptional regulator - - - 9.193e-277 892.0
HFD2_k127_1854697_10 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008363 404.0
HFD2_k127_1854697_11 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 346.0
HFD2_k127_1854697_12 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003542 362.0
HFD2_k127_1854697_13 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007185 311.0
HFD2_k127_1854697_15 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000009745 233.0
HFD2_k127_1854697_16 pfam abc1 K03688 - - 0.0000000000000000000000000000000000000000000000000000003528 198.0
HFD2_k127_1854697_18 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000004562 198.0
HFD2_k127_1854697_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 3.126e-249 781.0
HFD2_k127_1854697_20 PFAM UspA - - - 0.00000000000000000000008308 112.0
HFD2_k127_1854697_23 - - - - 0.000000000000003624 89.0
HFD2_k127_1854697_3 Belongs to the peptidase S16 family - - - 8.902e-228 740.0
HFD2_k127_1854697_4 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 3.342e-221 716.0
HFD2_k127_1854697_5 PFAM Aminotransferase class I and II K10206,K14261 - 2.6.1.83 1.411e-210 665.0
HFD2_k127_1854697_6 serine threonine protein kinase K08884,K12132 - 2.7.11.1 2.959e-209 666.0
HFD2_k127_1854697_7 acid phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004966 399.0
HFD2_k127_1854697_8 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 395.0
HFD2_k127_1893010_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1049.0
HFD2_k127_1893010_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 446.0
HFD2_k127_1893010_2 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004552 421.0
HFD2_k127_1893010_3 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 393.0
HFD2_k127_1893010_5 PGAP1-like protein K01046 - 3.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000005511 233.0
HFD2_k127_1893010_7 Multicopper oxidase K06324 - 1.16.3.3 0.00000000000000000000000000000000000004324 154.0
HFD2_k127_1903247_0 Male sterility protein K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 532.0
HFD2_k127_1903247_1 epimerase dehydratase K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 484.0
HFD2_k127_1933096_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006371 472.0
HFD2_k127_1933096_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004191 298.0
HFD2_k127_1933096_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000003041 265.0
HFD2_k127_1933096_3 thiolester hydrolase activity K06889 - - 0.00000000000000000000000000000000000000000000000000002894 198.0
HFD2_k127_1933096_4 Protein of unknown function (DUF456) K09793 - - 0.000000000000000000000000000000000000000000000006685 179.0
HFD2_k127_196408_0 - - - - 9.01e-200 632.0
HFD2_k127_196408_1 NAD(P)H quinone oxidoreductase, PIG3 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000811 500.0
HFD2_k127_196408_2 iron-nicotianamine transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009013 496.0
HFD2_k127_199082_0 Belongs to the RtcB family K14415 - 6.5.1.3 3.785e-212 681.0
HFD2_k127_199082_1 MatE K03327 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006519 552.0
HFD2_k127_199082_2 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005023 493.0
HFD2_k127_199082_3 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 396.0
HFD2_k127_199082_4 PFAM Archease protein family (DUF101 UPF0211) K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000006811 175.0
HFD2_k127_199082_5 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000000000004778 92.0
HFD2_k127_199082_6 Cupin 2, conserved barrel domain protein - - - 0.00000000000716 72.0
HFD2_k127_2042111_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000005771 178.0
HFD2_k127_2042111_1 Uncharacterized protein family UPF0016 - - - 0.000000000000000000000000000000197 126.0
HFD2_k127_2042111_2 DNA topoisomerase VI subunit A K03166 - 5.99.1.3 0.00000000000000002885 81.0
HFD2_k127_2042111_3 Redoxin - - - 0.000000000000003461 85.0
HFD2_k127_2063527_0 Periplasmic protein TonB links inner and outer membranes - - - 0.0 1015.0
HFD2_k127_2063527_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 574.0
HFD2_k127_2063527_2 Outer membrane efflux protein K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 380.0
HFD2_k127_2063527_3 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 335.0
HFD2_k127_2063527_4 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 302.0
HFD2_k127_2063527_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002801 252.0
HFD2_k127_207071_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370 - 1.7.5.1 0.0 2146.0
HFD2_k127_207071_1 PA domain - - - 0.0 1171.0
HFD2_k127_207071_2 ATP-dependent helicase HrpB K03579 - 3.6.4.13 0.0 1168.0
HFD2_k127_207071_3 Nitrate reductase, beta subunit K00371,K17051 - 1.7.5.1 1.174e-264 821.0
HFD2_k127_207071_4 Fungalysin metallopeptidase (M36) K01417 - - 2.308e-258 816.0
HFD2_k127_207071_5 PFAM major facilitator superfamily MFS_1 K02575 - - 8.812e-213 690.0
HFD2_k127_207071_6 TIGRFAM respiratory nitrate reductase, gamma subunit K00374 - 1.7.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007745 294.0
HFD2_k127_207071_7 Nitrate reductase delta subunit K00373 - - 0.00000000000000000000000000000000000000000000001825 176.0
HFD2_k127_207071_8 PFAM regulatory protein TetR - - - 0.0000000000000000000000000000000000000000000008192 192.0
HFD2_k127_207071_9 - - - - 0.0000003456 54.0
HFD2_k127_211736_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 2.863e-285 890.0
HFD2_k127_211736_1 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 1.348e-275 859.0
HFD2_k127_211736_10 PFAM PHP domain K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 325.0
HFD2_k127_211736_11 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000002241 256.0
HFD2_k127_211736_13 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000000000000000000002121 189.0
HFD2_k127_211736_14 - - - - 0.0000000000000000000000000000000000000000000006807 188.0
HFD2_k127_211736_15 - - - - 0.0000000000000000000000002177 108.0
HFD2_k127_211736_2 Sarcosine oxidase K00303 - 1.5.3.1 1.236e-224 720.0
HFD2_k127_211736_3 pseudouridine synthase activity K06176 - 5.4.99.27 6.606e-204 646.0
HFD2_k127_211736_4 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005347 569.0
HFD2_k127_211736_5 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004122 481.0
HFD2_k127_211736_6 2Fe-2S iron-sulfur cluster binding domain K00302 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006156 456.0
HFD2_k127_211736_7 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 381.0
HFD2_k127_211736_8 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 378.0
HFD2_k127_211736_9 Cell cycle protein K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008238 340.0
HFD2_k127_2191112_0 DNA helicase K03657 - 3.6.4.12 0.0 1074.0
HFD2_k127_2191112_1 ATP-binding region ATPase domain protein - - - 1.72e-227 722.0
HFD2_k127_2191112_10 response regulator, receiver - - - 0.0000000000000000000000000000000000002622 148.0
HFD2_k127_2191112_11 - - - - 0.0000000000000000000005431 110.0
HFD2_k127_2191112_2 adenosine deaminase K01488 - 3.5.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 565.0
HFD2_k127_2191112_3 Voltage-dependent anion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 523.0
HFD2_k127_2191112_4 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003533 465.0
HFD2_k127_2191112_5 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 388.0
HFD2_k127_2191112_6 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000006898 255.0
HFD2_k127_2191112_7 Belongs to the UPF0234 family K09767 - - 0.000000000000000000000000000000000000000000000000000000000000000000001272 250.0
HFD2_k127_2191112_8 PQQ enzyme repeat - - - 0.00000000000000000000000000000000000000000000000000000000009866 224.0
HFD2_k127_2191112_9 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000006057 210.0
HFD2_k127_2216088_0 Class II Aldolase and Adducin N-terminal domain - - - 1.005e-266 863.0
HFD2_k127_2216088_1 PFAM Band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 472.0
HFD2_k127_2216088_2 NAD dependent epimerase/dehydratase family K05281 - 1.3.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005767 445.0
HFD2_k127_2216088_3 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 390.0
HFD2_k127_2216088_4 ATP ADP translocase K03301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005231 347.0
HFD2_k127_2216088_5 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004351 312.0
HFD2_k127_2216088_6 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000002242 221.0
HFD2_k127_2216088_7 NfeD-like C-terminal, partner-binding - - - 0.00000000000000000000000000000000000000000002395 164.0
HFD2_k127_2216088_8 Haem-degrading - - - 0.000000000000000000000000000000002436 134.0
HFD2_k127_2229976_0 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000535 305.0
HFD2_k127_2229976_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000009203 231.0
HFD2_k127_2229976_2 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.000000000000000000000000000000000000000000000004668 178.0
HFD2_k127_2236590_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015,K15893 - 1.1.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003697 460.0
HFD2_k127_2236590_1 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.000000000000000000000000000000000000000000000001022 181.0
HFD2_k127_2236590_2 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.000000000000001395 86.0
HFD2_k127_2236590_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000002081 78.0
HFD2_k127_22379_0 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 587.0
HFD2_k127_22379_1 COG1233 Phytoene dehydrogenase and related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003121 434.0
HFD2_k127_22379_2 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003737 464.0
HFD2_k127_22379_3 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 314.0
HFD2_k127_22379_4 cyclic nucleotide-binding K10914 - - 0.000000000000000000001137 96.0
HFD2_k127_235718_0 penicillin-binding protein K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 578.0
HFD2_k127_235718_1 Cell division protein FtsL - - - 0.000001816 53.0
HFD2_k127_2425260_0 PFAM oxidoreductase FAD NAD(P)-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000579 336.0
HFD2_k127_2425260_1 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 286.0
HFD2_k127_2425260_2 Lysin motif K06194 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004704 285.0
HFD2_k127_2425260_3 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004106 276.0
HFD2_k127_2425260_4 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000001131 199.0
HFD2_k127_2460502_0 Belongs to the RtcB family K14415 - 6.5.1.3 3.218e-237 755.0
HFD2_k127_2460502_1 MatE K03327 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 558.0
HFD2_k127_2460502_2 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 517.0
HFD2_k127_2460502_3 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003648 388.0
HFD2_k127_2460502_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000387 268.0
HFD2_k127_2460502_5 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000000000000000000000000000000000000000000000000000000000794 218.0
HFD2_k127_2460502_6 PFAM Archease protein family (DUF101 UPF0211) K00974 - 2.7.7.72 0.00000000000000000000000000000000006472 153.0
HFD2_k127_2460502_7 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000003128 64.0
HFD2_k127_2461166_0 DEAD/H associated K03724 - - 0.0 1838.0
HFD2_k127_2461166_1 Belongs to the methyltransferase superfamily K07444,K12297 - 2.1.1.173,2.1.1.264 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007413 537.0
HFD2_k127_2461166_10 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 308.0
HFD2_k127_2461166_11 inorganic phosphate transmembrane transporter activity K02037,K02038 GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004651 289.0
HFD2_k127_2461166_12 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003849 276.0
HFD2_k127_2461166_13 Domain of unknown function (DUF4442) - - - 0.0000000000000000000000000000000000000000000000000000000005969 209.0
HFD2_k127_2461166_14 POT family K03305 - - 0.000000000000000000000000000000000009673 137.0
HFD2_k127_2461166_15 Domain of unknown function (DUF4833) - - - 0.0000000000000000000000001703 123.0
HFD2_k127_2461166_16 Thioredoxin-like - - - 0.0003328 44.0
HFD2_k127_2461166_2 Histidine kinase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 449.0
HFD2_k127_2461166_3 Two component transcriptional regulator, winged helix family K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005329 382.0
HFD2_k127_2461166_4 Belongs to the PstS family K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 366.0
HFD2_k127_2461166_5 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007716 359.0
HFD2_k127_2461166_6 O-methyltransferase K00588 - 2.1.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 325.0
HFD2_k127_2461166_7 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 331.0
HFD2_k127_2461166_8 chlorophyll binding K03286 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000072 310.0
HFD2_k127_2461166_9 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 308.0
HFD2_k127_249082_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 1.297e-311 961.0
HFD2_k127_249082_1 histidyl-tRNA synthetase K01892 - 6.1.1.21 4.725e-208 655.0
HFD2_k127_249082_10 Protein of unknown function DUF99 K09120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 295.0
HFD2_k127_249082_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002938 300.0
HFD2_k127_249082_12 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000000000000000000000000003944 185.0
HFD2_k127_249082_13 protein family UPF0079, ATPase K06925 - - 0.0000000000000000001468 91.0
HFD2_k127_249082_14 Glutathione peroxidase - - - 0.000000000000000001842 94.0
HFD2_k127_249082_15 PilZ domain - - - 0.00000000000001949 78.0
HFD2_k127_249082_2 N-terminal domain of unknown function (DUF4140) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 569.0
HFD2_k127_249082_3 imidazolonepropionase K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006452 533.0
HFD2_k127_249082_4 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 510.0
HFD2_k127_249082_5 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 481.0
HFD2_k127_249082_6 Belongs to the phosphatidylserine decarboxylase family K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009112 425.0
HFD2_k127_249082_7 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 406.0
HFD2_k127_249082_8 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 323.0
HFD2_k127_249082_9 Glutamine amidotransferases class-II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 311.0
HFD2_k127_2494659_0 heat shock protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 561.0
HFD2_k127_2494659_1 TIGRFAM cytochrome C family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008441 422.0
HFD2_k127_2494659_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000003877 74.0
HFD2_k127_250879_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003488 274.0
HFD2_k127_250879_1 transcriptional regulator K13643 - - 0.0000000000000000000002559 101.0
HFD2_k127_250879_2 - - - - 0.000000000004123 74.0
HFD2_k127_250879_3 Protein of unknown function (DUF1295) - - - 0.00003872 46.0
HFD2_k127_2592151_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1294.0
HFD2_k127_2592151_1 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 7.803e-204 662.0
HFD2_k127_2592151_10 Biopolymer transport protein ExbD/TolR - - - 0.0000000000000000000000000000000001752 149.0
HFD2_k127_2592151_2 nuclear chromosome segregation K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 490.0
HFD2_k127_2592151_3 AAA domain (Cdc48 subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004969 450.0
HFD2_k127_2592151_4 LysM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 407.0
HFD2_k127_2592151_5 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 305.0
HFD2_k127_2592151_6 DNA recombination-mediator protein A K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001137 301.0
HFD2_k127_2592151_7 MotA/TolQ/ExbB proton channel family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000256 259.0
HFD2_k127_2592151_8 Biopolymer transport protein ExbD/TolR - - - 0.00000000000000000000000000000000000000000000007131 175.0
HFD2_k127_2592151_9 protein trimerization - - - 0.00000000000000000000000000000000000000006896 174.0
HFD2_k127_264367_0 DUF1704 - - - 6.005e-211 664.0
HFD2_k127_264367_1 PFAM peptidase M48 Ste24p - - - 7.118e-211 673.0
HFD2_k127_264367_2 PFAM LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 311.0
HFD2_k127_264367_3 peptidylprolyl isomerase, FKBP-type K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000008755 121.0
HFD2_k127_2647948_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 1.013e-243 773.0
HFD2_k127_2647948_1 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC K06148,K16012 - - 0.0000000000000000000000000000000000000000000000000000000000001328 224.0
HFD2_k127_2647948_2 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000000000379 188.0
HFD2_k127_2647948_4 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.000000000000000000000005773 109.0
HFD2_k127_2647948_5 Regulatory protein, FmdB family - - - 0.00000000000000000000005115 112.0
HFD2_k127_2649323_0 Virulence factor BrkB K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004793 346.0
HFD2_k127_2649323_1 Ribonuclease E/G family K08301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 327.0
HFD2_k127_2649323_2 Belongs to the bacterial histone-like protein family K05788 - - 0.00000000000000000000000000000000000000000000000000000008261 197.0
HFD2_k127_2649323_3 Type III secretion protein K03230 - - 0.000000000000000000002179 95.0
HFD2_k127_2656540_0 epimerase dehydratase K01710,K01784 - 4.2.1.46,5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 495.0
HFD2_k127_2656540_1 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003576 449.0
HFD2_k127_2656540_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 436.0
HFD2_k127_2656540_3 UDP binding domain K02472 - 1.1.1.336 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 400.0
HFD2_k127_2656540_4 - - - - 0.0000000000000000000000001669 124.0
HFD2_k127_2656540_5 TPR repeat-containing protein - - - 0.0000000000000000007743 102.0
HFD2_k127_2661437_0 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.0 1180.0
HFD2_k127_2661437_1 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004125 546.0
HFD2_k127_2661437_2 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007797 432.0
HFD2_k127_2661437_3 Psort location CytoplasmicMembrane, score - - - 0.0000001297 59.0
HFD2_k127_2661437_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000004257 52.0
HFD2_k127_2664316_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 1.349e-266 852.0
HFD2_k127_2664316_1 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 542.0
HFD2_k127_2664316_10 PFAM PTS system fructose subfamily IIA component K02793 - 2.7.1.191 0.00000000000000000000000000000000000000001233 170.0
HFD2_k127_2664316_11 - - - - 0.000000000000000000000000000000000000007701 154.0
HFD2_k127_2664316_12 PTS HPr component phosphorylation site K11189 - - 0.0000000000000000000000000000002497 124.0
HFD2_k127_2664316_2 3'(2'),5'-bisphosphate nucleotidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 470.0
HFD2_k127_2664316_3 regulation of microtubule-based process K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 459.0
HFD2_k127_2664316_4 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 442.0
HFD2_k127_2664316_5 PFAM PTS system mannose fructose sorbose family IID component K02796 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005592 299.0
HFD2_k127_2664316_6 PTS system K02795 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009399 267.0
HFD2_k127_2664316_7 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000000001756 230.0
HFD2_k127_2664316_8 PFAM PTS system sorbose subfamily IIB component K02794 - 2.7.1.191 0.00000000000000000000000000000000000000000000000000000326 205.0
HFD2_k127_2664316_9 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000001766 177.0
HFD2_k127_2666054_0 Histidine ammonia-lyase K01745 - 4.3.1.3 7.125e-241 751.0
HFD2_k127_2701486_0 dioxygenase K00457,K16421 - 1.13.11.27,1.13.11.46 7.97e-200 627.0
HFD2_k127_2701486_1 homogentisate 12-dioxygenase K00451 - 1.13.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 618.0
HFD2_k127_2701486_2 Fumarylacetoacetate (FAA) hydrolase family K16171 - 3.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 489.0
HFD2_k127_2701486_3 Phosphoribosyl transferase domain K07100 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 368.0
HFD2_k127_2701486_4 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 293.0
HFD2_k127_2701486_5 maleylacetoacetate isomerase K01800,K01801 - 5.2.1.2,5.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000001389 265.0
HFD2_k127_2701486_6 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000851 233.0
HFD2_k127_2701486_7 IMP dehydrogenase activity - - - 0.00000000000000000000000000000005473 143.0
HFD2_k127_2709400_0 glycosyl transferase family 2 K21349 - 2.4.1.268 0.000000000000000000000000000000000000000000000000000000000000000004173 246.0
HFD2_k127_2709400_1 glycosyl transferase family K00697 - 2.4.1.15,2.4.1.347 0.000000000000000000000000001507 128.0
HFD2_k127_2718359_0 AAA ATPase domain - - - 0.0 1118.0
HFD2_k127_2718359_1 ATP-binding region ATPase domain protein - - - 6.879e-209 673.0
HFD2_k127_2718359_2 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004034 561.0
HFD2_k127_2718359_3 glycosyl transferase family 2 K21349 - 2.4.1.268 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 340.0
HFD2_k127_2718359_4 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001232 250.0
HFD2_k127_2718359_5 OPT oligopeptide transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000001062 214.0
HFD2_k127_2718359_6 PFAM Conserved TM helix repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000008257 192.0
HFD2_k127_2732283_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 2.215e-198 622.0
HFD2_k127_2732283_1 PBS lyase HEAT-like repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 500.0
HFD2_k127_2732283_2 Protein of unknown function (DUF533) K11962 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005005 289.0
HFD2_k127_275512_0 Amidase K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 598.0
HFD2_k127_275512_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000001293 255.0
HFD2_k127_2769958_0 Ser-tRNA(Ala) hydrolase activity K01872 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 483.0
HFD2_k127_2769958_1 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000001305 127.0
HFD2_k127_2769958_2 Domain of unknown function (DUF4082) - - - 0.00000003838 61.0
HFD2_k127_2769958_3 - - - - 0.0005698 52.0
HFD2_k127_2789922_0 WD40-like Beta Propeller Repeat - - - 1.792e-294 947.0
HFD2_k127_2789922_1 Aminotransferase K00812 - 2.6.1.1 7.484e-196 619.0
HFD2_k127_2789922_10 Serine hydrolase K07002 - - 0.000000000000000000000000000000000000000000000000000005006 204.0
HFD2_k127_2789922_11 Serine carboxypeptidase S28 - - - 0.00000000000000000000000000000000000006462 148.0
HFD2_k127_2789922_2 Cation efflux family K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004986 387.0
HFD2_k127_2789922_3 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 347.0
HFD2_k127_2789922_4 Bacterial transcriptional repressor C-terminal K16137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 292.0
HFD2_k127_2789922_5 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000006418 253.0
HFD2_k127_2789922_6 PFAM Activator of Hsp90 ATPase 1 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008074 250.0
HFD2_k127_2789922_7 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000116 233.0
HFD2_k127_2789922_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000006944 226.0
HFD2_k127_2794312_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 4.048e-263 814.0
HFD2_k127_2794312_1 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 580.0
HFD2_k127_2794312_2 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003602 588.0
HFD2_k127_2794312_3 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004303 496.0
HFD2_k127_2794312_4 MazG nucleotide pyrophosphohydrolase domain K02499,K04765 - 3.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 409.0
HFD2_k127_2794312_5 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000000000000001151 147.0
HFD2_k127_2794312_7 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000000000000001528 99.0
HFD2_k127_2802278_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 3.729e-197 651.0
HFD2_k127_2802278_1 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 624.0
HFD2_k127_2802278_10 AntiSigma factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003698 267.0
HFD2_k127_2802278_11 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000205 187.0
HFD2_k127_2802278_2 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 601.0
HFD2_k127_2802278_3 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004134 489.0
HFD2_k127_2802278_4 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 419.0
HFD2_k127_2802278_5 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006819 417.0
HFD2_k127_2802278_6 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 412.0
HFD2_k127_2802278_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008662 360.0
HFD2_k127_2802278_8 Response regulator receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 335.0
HFD2_k127_2802278_9 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 305.0
HFD2_k127_2833780_0 Belongs to the RimK family K05844 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016874,GO:0016879,GO:0016881,GO:0018169,GO:0018410,GO:0019538,GO:0031668,GO:0033554,GO:0036211,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0070739,GO:0071496,GO:0071704,GO:0140096,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 407.0
HFD2_k127_2833780_1 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 343.0
HFD2_k127_2833780_2 Heat shock 70 kDa protein K04043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 321.0
HFD2_k127_2833780_3 - - - - 0.000000000000000000000000000000000000008446 162.0
HFD2_k127_2833780_4 - - - - 0.0000000000001494 81.0
HFD2_k127_2833780_6 - - - - 0.00001748 50.0
HFD2_k127_2913847_0 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 1.156e-223 702.0
HFD2_k127_2913847_1 involved in molybdopterin and THIamine biosynthesis family 1 K03148,K21029,K22132 GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016829,GO:0016835,GO:0016836,GO:0030955,GO:0031402,GO:0031420,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0061503,GO:0061504,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.7.7.73,2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005886 372.0
HFD2_k127_2913847_2 Beta propeller domain - - - 0.0000000000000000005807 100.0
HFD2_k127_2947832_1 Nickel-dependent hydrogenase K00436 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004793 439.0
HFD2_k127_2947832_10 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000002269 134.0
HFD2_k127_2947832_11 Peptidase family M50 K11749 - - 0.00000000000000000000001706 101.0
HFD2_k127_2947832_12 - - - - 0.00000001306 65.0
HFD2_k127_2947832_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008191 452.0
HFD2_k127_2947832_3 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 335.0
HFD2_k127_2947832_4 coenzyme F420 hydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001325 300.0
HFD2_k127_2947832_5 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001482 284.0
HFD2_k127_2947832_6 AMMECR1 K09141 - - 0.000000000000000000000000000000000000000000000000000000000000000009155 236.0
HFD2_k127_2947832_7 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000002309 217.0
HFD2_k127_2947832_8 Acetoacetate decarboxylase (ADC) - - - 0.000000000000000000000000000000000000000000000002733 194.0
HFD2_k127_2947832_9 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000007697 157.0
HFD2_k127_2972858_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.011e-224 716.0
HFD2_k127_2972858_1 Aminotransferase K01845 - 5.4.3.8 2.413e-204 660.0
HFD2_k127_2972858_10 ATP hydrolysis coupled proton transport K02110,K02124 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000001322 108.0
HFD2_k127_2972858_13 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.000000004402 59.0
HFD2_k127_2972858_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 527.0
HFD2_k127_2972858_3 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009568 412.0
HFD2_k127_2972858_4 Belongs to the PdxA family K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 393.0
HFD2_k127_2972858_5 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008963 391.0
HFD2_k127_2972858_6 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003707 334.0
HFD2_k127_2972858_7 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005605 312.0
HFD2_k127_2972858_8 SurA N-terminal domain K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008882 306.0
HFD2_k127_2972858_9 ATP synthesis coupled proton transport K02109 - - 0.0000000000000000000000000000000000000000000000000000000002266 212.0
HFD2_k127_2997062_0 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 473.0
HFD2_k127_2997062_1 endonuclease activity K07451 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002134 246.0
HFD2_k127_2997062_2 TonB C terminal K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000001512 239.0
HFD2_k127_2997062_3 reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000001823 205.0
HFD2_k127_2997062_4 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000000000000000000423 181.0
HFD2_k127_2997062_5 endonuclease activity K07451 - - 0.000000000000000000000000000000000000000005665 169.0
HFD2_k127_2997062_6 Tryptophan halogenase - - - 0.00000000000000000000000000006888 117.0
HFD2_k127_2997062_7 - - - - 0.0000000000000000000001071 111.0
HFD2_k127_302562_0 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008608 441.0
HFD2_k127_302562_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000381 265.0
HFD2_k127_302562_2 - - - - 0.0000000000000000000000000000000000000000000005284 167.0
HFD2_k127_302562_3 sequence-specific DNA binding - - - 0.000000000000000000000000000000000008749 139.0
HFD2_k127_302562_4 ABC transporter K06147,K06148 - - 0.00000000000000002596 81.0
HFD2_k127_3033531_0 peptidase U62 modulator of DNA gyrase - - - 1.396e-211 664.0
HFD2_k127_3033531_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 398.0
HFD2_k127_3033531_2 peptide catabolic process K01256 - 3.4.11.2 0.00000000000000000000000000000000000000000000000000000000000000002145 255.0
HFD2_k127_3033531_4 - - - - 0.00003081 55.0
HFD2_k127_3052074_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 5.757e-235 742.0
HFD2_k127_3052074_1 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 2.149e-219 710.0
HFD2_k127_3052074_2 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002949 460.0
HFD2_k127_3052074_3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00615,K00616,K13810 - 2.2.1.1,2.2.1.2,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 441.0
HFD2_k127_3052074_4 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000003939 246.0
HFD2_k127_3052074_5 thiolester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000001144 211.0
HFD2_k127_3052074_6 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K12976,K22110 - - 0.0000000001163 64.0
HFD2_k127_3113047_0 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 2.552e-208 653.0
HFD2_k127_3113047_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 390.0
HFD2_k127_3113047_2 Heat shock 70 kDa protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 370.0
HFD2_k127_3113047_3 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.0000000000000000000000000000000000000000000000001242 199.0
HFD2_k127_3113047_4 Preprotein translocase SecG subunit K03075 - - 0.0000000000000000000000000001104 130.0
HFD2_k127_3139610_0 Involved in arsenical resistance. Thought to form the channel of an arsenite pump - - - 4.649e-195 617.0
HFD2_k127_3139610_1 Nucleoside H+ symporter K05820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 446.0
HFD2_k127_3139610_2 Diacylglycerol kinase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 420.0
HFD2_k127_3139610_3 Nucleotidyl transferase K00966,K16881 - 2.7.7.13,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 410.0
HFD2_k127_3139610_4 Protein serine threonine phosphatase K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005373 398.0
HFD2_k127_3139610_5 GAF domain-containing protein K08968 - 1.8.4.14 0.0000000000000000000000000000000000000000000003609 186.0
HFD2_k127_3139610_6 EXOIII K02342 - 2.7.7.7 0.00000000000000000000000000000003624 127.0
HFD2_k127_3139610_7 heat shock protein binding - - - 0.00000000000000000004218 91.0
HFD2_k127_3301243_0 MMPL family - - - 1.63e-243 773.0
HFD2_k127_3301243_1 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000000000000000000000000003672 204.0
HFD2_k127_3404338_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 9.741e-202 634.0
HFD2_k127_3404338_1 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005438 601.0
HFD2_k127_3404338_2 Acyl-CoA dehydrogenase, C-terminal domain K00249,K11731 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008159 593.0
HFD2_k127_3404338_3 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000002341 266.0
HFD2_k127_3404338_4 CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000000000000000000008391 153.0
HFD2_k127_3404338_5 - - - - 0.00000000000000000000000000000000000002256 151.0
HFD2_k127_3404338_6 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0000000000000000000000000001107 116.0
HFD2_k127_344536_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0 1198.0
HFD2_k127_344536_1 Tetratricopeptide repeats - - - 2.206e-254 809.0
HFD2_k127_344536_2 Surface antigen - - - 1.508e-233 814.0
HFD2_k127_344536_3 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 485.0
HFD2_k127_344536_4 Glutathione-dependent formaldehyde-activating - - - 0.0000000000000000007902 87.0
HFD2_k127_3549232_0 penicillin-binding protein K03587 - 3.4.16.4 7.267e-233 742.0
HFD2_k127_3549232_1 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 606.0
HFD2_k127_3549232_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 596.0
HFD2_k127_3549232_3 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003652 616.0
HFD2_k127_3549232_4 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004159 453.0
HFD2_k127_3549232_5 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003201 460.0
HFD2_k127_3549232_6 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000001865 231.0
HFD2_k127_3549232_8 cell division K03586 GO:0000003,GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0019954,GO:0022402,GO:0022414,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0043093,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944 - 0.000000000000006286 87.0
HFD2_k127_3569793_0 peptidase S9A, prolyl oligopeptidase domain protein beta-propeller K01322 - 3.4.21.26 2.268e-307 958.0
HFD2_k127_3569793_1 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003981 501.0
HFD2_k127_3569793_10 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000006747 185.0
HFD2_k127_3569793_11 MOSC domain - - - 0.000000000000000000000000000000000000000000000000009031 184.0
HFD2_k127_3569793_12 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000000000000000001174 178.0
HFD2_k127_3569793_13 response to copper ion K16915 - - 0.0000000000000000000000000000001052 138.0
HFD2_k127_3569793_14 Domain of unknown function (DUF4198) K10094 - - 0.00000000000000000000005697 111.0
HFD2_k127_3569793_15 DNA-binding transcription factor activity - - - 0.00000000000000001071 88.0
HFD2_k127_3569793_17 TrkA-C domain K03455 - - 0.0000000000000006415 79.0
HFD2_k127_3569793_2 Sodium/hydrogen exchanger family K11105 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 505.0
HFD2_k127_3569793_3 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005339 351.0
HFD2_k127_3569793_4 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 345.0
HFD2_k127_3569793_5 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006909 291.0
HFD2_k127_3569793_6 Putative MetA-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000002885 224.0
HFD2_k127_3569793_7 DnaJ molecular chaperone homology domain - - - 0.00000000000000000000000000000000000000000000000000000001168 216.0
HFD2_k127_3569793_8 Belongs to the NiCoT transporter (TC 2.A.52) family K08970 - - 0.000000000000000000000000000000000000000000000000000007166 209.0
HFD2_k127_3579957_0 AlkA N-terminal domain K13529,K13530 - 3.2.2.21 3.488e-209 670.0
HFD2_k127_3579957_1 Glucodextranase, domain N K01178 - 3.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 535.0
HFD2_k127_3579957_2 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000001179 224.0
HFD2_k127_3579957_3 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22 0.0000000001101 63.0
HFD2_k127_3587935_0 ABC transporter, ATP-binding protein - - - 3.46e-276 859.0
HFD2_k127_3587935_1 CobW/HypB/UreG, nucleotide-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 489.0
HFD2_k127_3587935_2 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000608 430.0
HFD2_k127_3587935_3 Aminotransferase class-III K00819,K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.13,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000714 443.0
HFD2_k127_3587935_4 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA K07444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 389.0
HFD2_k127_3587935_5 Amino acid kinase family K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000007228 239.0
HFD2_k127_3587935_6 AcrB/AcrD/AcrF family - - - 0.000000000000000000000000000000000000000000000000000000001444 205.0
HFD2_k127_3587935_7 cysteine-type peptidase activity - - - 0.000000000000000000000000000000000000000000003867 173.0
HFD2_k127_3587935_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000006968 136.0
HFD2_k127_3588617_0 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 565.0
HFD2_k127_3588617_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000005959 131.0
HFD2_k127_3588617_2 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000001711 55.0
HFD2_k127_3590173_0 glutaminyl-tRNA K01886 - 6.1.1.18 0.0 1138.0
HFD2_k127_3590173_1 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 4.579e-312 965.0
HFD2_k127_3590173_10 Tannase and feruloyl esterase - - - 0.00000000000000000000000000000000000000000000000000000000004738 223.0
HFD2_k127_3590173_12 energy transducer activity K03832 - - 0.00000000000000000000000000000000000000000174 180.0
HFD2_k127_3590173_14 Metallo-beta-lactamase superfamily - - - 0.00000000000001981 87.0
HFD2_k127_3590173_2 SMART Elongator protein 3 MiaB NifB - - - 2.039e-196 651.0
HFD2_k127_3590173_3 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006846 494.0
HFD2_k127_3590173_4 Transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006659 409.0
HFD2_k127_3590173_5 BAAT / Acyl-CoA thioester hydrolase C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 338.0
HFD2_k127_3590173_6 Membrane transport protein K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 328.0
HFD2_k127_3590173_7 Tellurite resistance protein TerB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005695 320.0
HFD2_k127_3590173_8 PFAM Glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001739 257.0
HFD2_k127_3590173_9 Enoyl-(Acyl carrier protein) reductase K12677 - - 0.0000000000000000000000000000000000000000000000000000000000000000001252 243.0
HFD2_k127_3607954_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1302.0
HFD2_k127_3607954_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 4.01e-276 858.0
HFD2_k127_3607954_10 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007819 359.0
HFD2_k127_3607954_11 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 351.0
HFD2_k127_3607954_12 ABC transporter, ATP-binding protein K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 332.0
HFD2_k127_3607954_13 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005424 318.0
HFD2_k127_3607954_14 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 299.0
HFD2_k127_3607954_15 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 302.0
HFD2_k127_3607954_16 ABC-type transport system involved in multi-copper enzyme maturation permease component K19341 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002471 281.0
HFD2_k127_3607954_17 TPM domain K06872 - - 0.000000000000000000000000000000000000000000000000000000000000000003345 235.0
HFD2_k127_3607954_18 Membrane K08988 - - 0.00000000000000000000000000000000000000000000000000000000000000000646 231.0
HFD2_k127_3607954_19 - - - - 0.000000000000000000000000000000000000000000000000000000000001906 233.0
HFD2_k127_3607954_2 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005337 587.0
HFD2_k127_3607954_20 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000003372 207.0
HFD2_k127_3607954_21 Iron-sulfur cluster assembly protein - - - 0.0000000000000000000000000000000000000000000000000000001334 213.0
HFD2_k127_3607954_22 SUF system FeS assembly protein K04488 - - 0.0000000000000000000000000000000000000000000000004907 195.0
HFD2_k127_3607954_23 6-O-methylguanine DNA methyltransferase, DNA binding domain K07443 - - 0.00000000000000000000000000000000000000000004925 163.0
HFD2_k127_3607954_24 histone H2A K63-linked ubiquitination K02283 - - 0.00000000000000000000000000000000009746 152.0
HFD2_k127_3607954_25 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.00000000000000000000000000000001161 133.0
HFD2_k127_3607954_26 Protein of unknown function (DUF2470) K07226 - - 0.0000000000000000000000000000001181 143.0
HFD2_k127_3607954_27 Peptidase MA superfamily - - - 0.0000000000003659 79.0
HFD2_k127_3607954_3 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006779 502.0
HFD2_k127_3607954_4 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007002 458.0
HFD2_k127_3607954_5 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 441.0
HFD2_k127_3607954_6 FeS assembly protein SufD K09015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 410.0
HFD2_k127_3607954_7 FeS assembly ATPase SufC K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 387.0
HFD2_k127_3607954_8 FeS assembly protein SufB K09014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 361.0
HFD2_k127_3607954_9 Methyltransferase type 11 K03892 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 364.0
HFD2_k127_3615965_0 PFAM phosphoesterase, RecJ domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 539.0
HFD2_k127_3615965_1 Aminotransferase, class V K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004827 511.0
HFD2_k127_3615965_2 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006948 391.0
HFD2_k127_3615965_3 Fic/DOC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 316.0
HFD2_k127_3615965_4 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002545 286.0
HFD2_k127_3615965_5 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000002474 153.0
HFD2_k127_3615965_6 Serine Threonine protein kinase K12132 - 2.7.11.1 0.000000003351 58.0
HFD2_k127_3615965_7 Putative 2OG-Fe(II) oxygenase - - - 0.0000006053 62.0
HFD2_k127_3640747_0 Fungal trichothecene efflux pump (TRI12) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007595 529.0
HFD2_k127_3661183_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 510.0
HFD2_k127_3661183_1 Response regulator, receiver K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004537 424.0
HFD2_k127_3685057_0 Acyl-CoA dehydrogenase N terminal K00248 - 1.3.8.1 2.209e-267 835.0
HFD2_k127_3685057_1 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 6.653e-244 764.0
HFD2_k127_3685057_10 denitrification pathway K02569 - - 0.0000000000000000000000000000000000001977 151.0
HFD2_k127_3685057_11 PFAM Hemerythrin HHE cation binding domain protein K07216 - - 0.00000000000000000000000000000000004306 143.0
HFD2_k127_3685057_12 metallopeptidase activity - - - 0.000000000000000000000000007249 128.0
HFD2_k127_3685057_14 cAMP-dependent protein kinase regulatory subunit K04739 GO:0000003,GO:0000166,GO:0000228,GO:0000785,GO:0000790,GO:0001932,GO:0001933,GO:0002831,GO:0002832,GO:0003674,GO:0004857,GO:0004860,GO:0004862,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005886,GO:0005952,GO:0006469,GO:0006950,GO:0006979,GO:0007154,GO:0008104,GO:0008150,GO:0008277,GO:0008603,GO:0009266,GO:0009267,GO:0009405,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009653,GO:0009892,GO:0009966,GO:0009968,GO:0009987,GO:0009991,GO:0010563,GO:0010570,GO:0010605,GO:0010639,GO:0010646,GO:0010648,GO:0016020,GO:0017076,GO:0019207,GO:0019210,GO:0019220,GO:0019222,GO:0019887,GO:0019954,GO:0022603,GO:0023051,GO:0023057,GO:0030154,GO:0030234,GO:0030291,GO:0030435,GO:0030436,GO:0030447,GO:0030448,GO:0030551,GO:0030552,GO:0030554,GO:0031279,GO:0031281,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0031667,GO:0031668,GO:0031669,GO:0031974,GO:0031981,GO:0032101,GO:0032102,GO:0032104,GO:0032105,GO:0032107,GO:0032108,GO:0032268,GO:0032269,GO:0032386,GO:0032388,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032879,GO:0032880,GO:0032991,GO:0033036,GO:0033043,GO:0033157,GO:0033554,GO:0033673,GO:0034305,GO:0034599,GO:0034605,GO:0034613,GO:0036094,GO:0036170,GO:0036180,GO:0040007,GO:0040008,GO:0042173,GO:0042221,GO:0042325,GO:0042326,GO:0042594,GO:0043085,GO:0043086,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043549,GO:0043934,GO:0043936,GO:0043937,GO:0043938,GO:0043943,GO:0043945,GO:0043949,GO:0043951,GO:0044092,GO:0044093,GO:0044182,GO:0044419,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0045595,GO:0045597,GO:0045744,GO:0045761,GO:0045762,GO:0045786,GO:0045859,GO:0045881,GO:0045926,GO:0045936,GO:0046578,GO:0046580,GO:0046822,GO:0046824,GO:0046825,GO:0046827,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048646,GO:0048856,GO:0048869,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051049,GO:0051050,GO:0051056,GO:0051058,GO:0051094,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051174,GO:0051179,GO:0051222,GO:0051223,GO:0051246,GO:0051248,GO:0051338,GO:0051339,GO:0051348,GO:0051349,GO:0051445,GO:0051447,GO:0051641,GO:0051704,GO:0051716,GO:0051726,GO:0051783,GO:0051784,GO:0060255,GO:0060258,GO:0060341,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070201,GO:0070727,GO:0070887,GO:0071496,GO:0071900,GO:0071901,GO:0071944,GO:0080090,GO:0080134,GO:0090087,GO:0090316,GO:0097159,GO:0097271,GO:0097367,GO:0098772,GO:0106070,GO:0106072,GO:0110033,GO:0110034,GO:1900428,GO:1900429,GO:1900434,GO:1900435,GO:1900443,GO:1900444,GO:1901265,GO:1901363,GO:1902531,GO:1902532,GO:1902659,GO:1902660,GO:1903664,GO:1903666,GO:1903827,GO:1903829,GO:1904951,GO:2000241,GO:2000242,GO:2000479,GO:2000480 - 0.00000000000009521 78.0
HFD2_k127_3685057_15 LysM domain - - - 0.0000002136 65.0
HFD2_k127_3685057_2 AsmA family K07289 - - 7.29e-226 730.0
HFD2_k127_3685057_3 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002304 308.0
HFD2_k127_3685057_4 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003141 286.0
HFD2_k127_3685057_5 ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002017 279.0
HFD2_k127_3685057_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000821 269.0
HFD2_k127_3685057_7 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000001804 249.0
HFD2_k127_3685057_8 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000007533 244.0
HFD2_k127_3685057_9 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000001253 170.0
HFD2_k127_3707708_0 DNA internalization-related competence protein ComEC Rec2 K02238 - - 4.484e-209 683.0
HFD2_k127_3707708_1 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003592 524.0
HFD2_k127_3707708_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005563 432.0
HFD2_k127_3707708_3 Transcriptional regulator, CarD family K07736 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003766 311.0
HFD2_k127_3707708_5 Carbohydrate family 9 binding domain-like - - - 0.0008002 42.0
HFD2_k127_3711430_0 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 537.0
HFD2_k127_3711430_1 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 536.0
HFD2_k127_3711430_2 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 392.0
HFD2_k127_3711430_3 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007052 321.0
HFD2_k127_3711430_4 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000004914 259.0
HFD2_k127_3711430_5 PFAM thioesterase superfamily protein - - - 0.00000000000000000000009504 108.0
HFD2_k127_3719105_0 ATP dependent DNA ligase domain protein K01971 - 6.5.1.1 0.0 1068.0
HFD2_k127_3719105_1 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 2.84e-230 740.0
HFD2_k127_3719105_10 - - - - 0.00000000000000000000000000000000000000000000000001353 190.0
HFD2_k127_3719105_11 Protein of Unknown function (DUF2784) - - - 0.0000000000000000000000000000000000000006177 154.0
HFD2_k127_3719105_12 Domain of unknown function (DU1801) - - - 0.00000000000000000000000002258 115.0
HFD2_k127_3719105_13 3-Demethylubiquinone-9 3-methyltransferase - - - 0.0000000000000431 72.0
HFD2_k127_3719105_15 - - - - 0.0002664 54.0
HFD2_k127_3719105_2 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004807 377.0
HFD2_k127_3719105_3 Gluconolactonase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000676 371.0
HFD2_k127_3719105_4 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005381 328.0
HFD2_k127_3719105_5 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005619 282.0
HFD2_k127_3719105_6 Alpha/beta hydrolase family K07020 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002768 266.0
HFD2_k127_3719105_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K20444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007658 278.0
HFD2_k127_3719105_8 chlorophyll binding - - - 0.0000000000000000000000000000000000000000000000000000000000000001501 225.0
HFD2_k127_3719105_9 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000008752 228.0
HFD2_k127_3729149_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 3.714e-255 790.0
HFD2_k127_3729149_1 Heat shock 70 kDa protein - - - 2.031e-251 781.0
HFD2_k127_3729149_10 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000008185 89.0
HFD2_k127_3729149_2 Asparagine synthase K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007385 416.0
HFD2_k127_3729149_3 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 339.0
HFD2_k127_3729149_4 domain protein K21029,K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 320.0
HFD2_k127_3729149_7 Catalyzes the synthesis of activated sulfate K00390,K00860 - 1.8.4.10,1.8.4.8,2.7.1.25 0.00000000000000000000000000000000000000000000000000000000000000005356 235.0
HFD2_k127_3729149_8 Involved in molybdopterin and thiamine biosynthesis, family 2 - - - 0.000000000000000000000000000000000000000000000002416 186.0
HFD2_k127_3729149_9 Belongs to the sulfur carrier protein TusA family - - - 0.000000000000000000000000000000000001973 141.0
HFD2_k127_3748885_0 Stage II sporulation protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 527.0
HFD2_k127_3748885_1 Aminotransferase K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004745 407.0
HFD2_k127_3748885_2 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000004823 243.0
HFD2_k127_3748885_6 RDD family - - - 0.0000000000000000000000000000307 124.0
HFD2_k127_3768747_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0 1026.0
HFD2_k127_3768747_1 Helix-hairpin-helix class 2 (Pol1 family) motifs - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002865 437.0
HFD2_k127_3768747_2 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005388 320.0
HFD2_k127_3768747_3 COG2513 PEP phosphonomutase and related enzymes K03417 - 4.1.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 327.0
HFD2_k127_3768747_4 - - - - 0.00000000000000000000000000000000000000000000000000007467 198.0
HFD2_k127_3768747_5 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine K04068 - 1.97.1.4 0.00000000000000000000000000000000000000000000000001342 191.0
HFD2_k127_3774671_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 8.093e-242 751.0
HFD2_k127_3774671_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 537.0
HFD2_k127_3774671_2 major pilin protein fima - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003351 410.0
HFD2_k127_3774671_3 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002887 325.0
HFD2_k127_3825418_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 342.0
HFD2_k127_3825418_1 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00000000000000000000000000000000000000004348 158.0
HFD2_k127_3825418_2 peptidyl-tyrosine sulfation - - - 0.000000587 61.0
HFD2_k127_3827843_0 PFAM permease YjgP YjgQ family protein K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009712 334.0
HFD2_k127_3827843_1 PFAM permease YjgP YjgQ family protein K07091 - - 0.00000000000000000000000000001997 122.0
HFD2_k127_3827843_2 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0008879,GO:0009058,GO:0009059,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0045226,GO:0046379,GO:0046872,GO:0071704,GO:1901576 2.7.7.24 0.00000000000000001779 96.0
HFD2_k127_3834160_0 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 545.0
HFD2_k127_3834160_1 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004714 263.0
HFD2_k127_3834160_2 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000606 160.0
HFD2_k127_3834160_3 Belongs to the radical SAM superfamily. RlmN family K06941 - 2.1.1.192 0.000000000000000004763 83.0
HFD2_k127_3834160_4 Protein of unknown function (DUF3106) - - - 0.000000000002064 78.0
HFD2_k127_3834160_5 Putative zinc-finger - - - 0.000002203 61.0
HFD2_k127_3861939_0 formate dehydrogenase K00127 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001158 269.0
HFD2_k127_3861939_1 Necessary for formate dehydrogenase activity K02380 - - 0.000000000000000000000000000003202 136.0
HFD2_k127_3861939_2 4Fe-4S dicluster domain K00124 - - 0.0000000000000000000000000001485 115.0
HFD2_k127_3871829_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 340.0
HFD2_k127_3871829_1 PFAM Class I peptide chain release factor K15034 - - 0.0000000000000000000000000000000000001088 145.0
HFD2_k127_3912272_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1405.0
HFD2_k127_3912272_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 2.28e-321 1013.0
HFD2_k127_3912272_10 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 299.0
HFD2_k127_3912272_13 - - - - 0.0000000000000000000000000000000000000000000000000000000001831 206.0
HFD2_k127_3912272_14 FR47-like protein K03789 - 2.3.1.128 0.00000000000000000000000000000000000000000000000000000261 206.0
HFD2_k127_3912272_16 lytic transglycosylase activity - - - 0.0000000000000000000000000000000000000000000000001173 186.0
HFD2_k127_3912272_17 PFAM DivIVA family protein K04074 - - 0.0000000000000000000000000000000000000000000000008144 175.0
HFD2_k127_3912272_2 peptidase S9B dipeptidylpeptidase IV domain protein K01278 - 3.4.14.5 1.001e-243 773.0
HFD2_k127_3912272_21 SMART helix-turn-helix domain protein K15539 - - 0.000000000000000155 94.0
HFD2_k127_3912272_3 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003746 576.0
HFD2_k127_3912272_4 DnaJ C terminal domain K03686,K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 544.0
HFD2_k127_3912272_5 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 490.0
HFD2_k127_3912272_6 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004325 483.0
HFD2_k127_3912272_7 lyase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 400.0
HFD2_k127_3912272_8 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008864 341.0
HFD2_k127_3912272_9 TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 308.0
HFD2_k127_3929827_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 5.111e-258 801.0
HFD2_k127_3929827_1 Belongs to the heat shock protein 70 family K04043 - - 1.585e-232 748.0
HFD2_k127_3929827_10 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003674 424.0
HFD2_k127_3929827_11 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 419.0
HFD2_k127_3929827_12 Asparaginase K13051 - 3.4.19.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 412.0
HFD2_k127_3929827_13 Acyl CoA acetate 3-ketoacid CoA transferase beta subunit K01029 - 2.8.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009436 377.0
HFD2_k127_3929827_14 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01028 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008954 364.0
HFD2_k127_3929827_15 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008239 370.0
HFD2_k127_3929827_16 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 332.0
HFD2_k127_3929827_17 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 298.0
HFD2_k127_3929827_18 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005662 304.0
HFD2_k127_3929827_19 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000001515 229.0
HFD2_k127_3929827_2 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 2.043e-219 688.0
HFD2_k127_3929827_21 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000000000000000000002659 230.0
HFD2_k127_3929827_22 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000004586 203.0
HFD2_k127_3929827_23 PFAM Cyclic nucleotide-binding - - - 0.000000000000000000000000000000000000000000000000000003795 207.0
HFD2_k127_3929827_24 Sigma-70 region 2 - - - 0.00000000000000000000000000000000000000000000000000002679 204.0
HFD2_k127_3929827_25 - - - - 0.00000000000000000000000000000000000000001281 171.0
HFD2_k127_3929827_26 PilZ domain - - - 0.00000000000000000000000000000000000000003852 169.0
HFD2_k127_3929827_27 - K07018 - - 0.0000000000000000000000000000000004702 140.0
HFD2_k127_3929827_28 glyoxalase III activity - - - 0.00000000000000000012 102.0
HFD2_k127_3929827_29 - - - - 0.0000000000000003602 93.0
HFD2_k127_3929827_3 Belongs to the thiolase family K00626 - 2.3.1.9 6.987e-197 621.0
HFD2_k127_3929827_30 - - - - 0.000000000000003806 86.0
HFD2_k127_3929827_31 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K06969 - 2.1.1.191 0.0000333 57.0
HFD2_k127_3929827_4 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 572.0
HFD2_k127_3929827_5 VWA domain containing CoxE-like protein K07161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009264 569.0
HFD2_k127_3929827_6 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 570.0
HFD2_k127_3929827_7 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 531.0
HFD2_k127_3929827_8 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 526.0
HFD2_k127_3929827_9 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K02056,K05776,K10441,K10539,K10542,K10545,K10548 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 436.0
HFD2_k127_3943133_0 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004409 623.0
HFD2_k127_3943133_1 Acetamidase/Formamidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 454.0
HFD2_k127_3943133_3 - - - - 0.00000000000000000000000003505 115.0
HFD2_k127_39547_0 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001409 260.0
HFD2_k127_39547_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0001013 51.0
HFD2_k127_400458_0 Major Facilitator Superfamily - - - 3.1e-208 656.0
HFD2_k127_400458_1 Cellulose biosynthesis protein BcsQ K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 516.0
HFD2_k127_400458_10 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000007266 125.0
HFD2_k127_400458_2 CBS domain containing protein K06189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 444.0
HFD2_k127_400458_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 390.0
HFD2_k127_400458_4 deoxyhypusine monooxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 399.0
HFD2_k127_400458_5 PFAM peptidase T2 asparaginase 2 K01444,K13051 - 3.4.19.5,3.5.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004003 329.0
HFD2_k127_400458_6 hydrolase of the alpha beta superfamily K07018 - - 0.000000000000000000000000000000000000000000000000000000000000000000114 244.0
HFD2_k127_400458_7 nuclear chromosome segregation K13582,K21471 - - 0.00000000000000000000000000000000000000000000000000000000004717 231.0
HFD2_k127_400458_8 endonuclease activity K07451 - - 0.0000000000000000000000000000000000000000000000000000004559 201.0
HFD2_k127_400458_9 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000005866 146.0
HFD2_k127_40312_0 ABC transporter K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 380.0
HFD2_k127_40312_1 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009549 369.0
HFD2_k127_40312_2 Pkd domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 324.0
HFD2_k127_40312_3 Domain of unknown function (DUF3943) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009994 263.0
HFD2_k127_40312_4 Predicted membrane protein (DUF2339) - - - 0.0000000000000000000000000000000002888 151.0
HFD2_k127_40312_6 Stigma-specific protein, Stig1 - - - 0.000000000002021 73.0
HFD2_k127_4038722_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 1.513e-199 635.0
HFD2_k127_4038722_1 type ii restriction enzyme K01155 - 3.1.21.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009957 582.0
HFD2_k127_4038722_10 shikimate kinase activity K00891,K13829 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000002486 203.0
HFD2_k127_4038722_11 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000005121 207.0
HFD2_k127_4038722_12 PFAM Chorismate mutase of the AroH class K06208 - 5.4.99.5 0.000000000000000000000000000000000000000000000001581 175.0
HFD2_k127_4038722_2 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 571.0
HFD2_k127_4038722_3 Serine Threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008446 561.0
HFD2_k127_4038722_4 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003688 489.0
HFD2_k127_4038722_5 PFAM DAHP synthetase I KDSA K03856,K04516 - 2.5.1.54,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004009 413.0
HFD2_k127_4038722_6 carbon starvation protein CstA K06200 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003216 417.0
HFD2_k127_4038722_7 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 402.0
HFD2_k127_4038722_8 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003422 370.0
HFD2_k127_4038722_9 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005836 321.0
HFD2_k127_406259_0 PFAM AMP-dependent synthetase and ligase - - - 0.0 1982.0
HFD2_k127_406259_1 Peptidase family M3 K01284 - 3.4.15.5 0.0 1030.0
HFD2_k127_406259_10 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007443 261.0
HFD2_k127_406259_11 PFAM NADH ubiquinone oxidoreductase, 20 - - - 0.00000000000000000000000000000000000000000000000000000000000000002814 240.0
HFD2_k127_406259_12 NADH dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000001325 232.0
HFD2_k127_406259_13 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000636 154.0
HFD2_k127_406259_14 indolepyruvate ferredoxin oxidoreductase activity K00179,K08941 - 1.2.7.8 0.00000000000000000000000000000000002653 143.0
HFD2_k127_406259_15 hydrogenase 4 membrane K12140 - - 0.00000000000000000000000000001155 135.0
HFD2_k127_406259_16 ribonucleoside-diphosphate reductase activity K07735 - - 0.00000000000000000000000000005274 135.0
HFD2_k127_406259_2 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 8.782e-200 636.0
HFD2_k127_406259_3 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 3.86e-197 625.0
HFD2_k127_406259_4 Belongs to the alpha-IPM synthase homocitrate synthase family K01655 - 2.3.3.14 1.471e-195 622.0
HFD2_k127_406259_5 PFAM NADH Ubiquinone plastoquinone (complex I) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005259 468.0
HFD2_k127_406259_6 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K15830 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005003 460.0
HFD2_k127_406259_7 plastoquinone (Complex I) K12141 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 397.0
HFD2_k127_406259_8 Enoyl-(Acyl carrier protein) reductase K13774 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008376 389.0
HFD2_k127_406259_9 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003957 343.0
HFD2_k127_4080954_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1055.0
HFD2_k127_4158601_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 496.0
HFD2_k127_41590_0 Acetyl-coenzyme A transporter 1 K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 441.0
HFD2_k127_41590_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 291.0
HFD2_k127_41590_2 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000000008452 220.0
HFD2_k127_4217582_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 1.002e-254 798.0
HFD2_k127_4217582_1 Binding-protein-dependent transport system inner membrane component K02042 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 548.0
HFD2_k127_4217582_2 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 457.0
HFD2_k127_4217582_3 Bacterial extracellular solute-binding proteins, family 3 K02044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 418.0
HFD2_k127_4217582_4 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001779 265.0
HFD2_k127_4217582_5 PFAM cytochrome C oxidase mono-heme subunit FixO K00405 - - 0.0000000000000000000000000000000000000000000001337 179.0
HFD2_k127_4217582_7 S-acyltransferase activity K00627 - 2.3.1.12 0.000000000000000000004511 94.0
HFD2_k127_4217582_8 OsmC-like protein - - - 0.0005953 46.0
HFD2_k127_4228744_0 Type III secretion protein K03230 - - 1.664e-241 785.0
HFD2_k127_4228744_1 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401,K03229 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004545 302.0
HFD2_k127_4228744_2 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02416,K02417,K03225 GO:0005575,GO:0005623,GO:0005886,GO:0006935,GO:0008150,GO:0009288,GO:0009425,GO:0009605,GO:0016020,GO:0040011,GO:0042221,GO:0042330,GO:0042995,GO:0043226,GO:0043228,GO:0044403,GO:0044419,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0052116,GO:0052126,GO:0052127,GO:0052143,GO:0052192,GO:0052195,GO:0052216,GO:0052243,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003718 288.0
HFD2_k127_4228744_3 type iii secretion K03226 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001887 260.0
HFD2_k127_4228744_4 Secretory protein of YscJ/FliF family K03222 - - 0.00000000000000000000000000000000000000000000000000000000000000000001693 239.0
HFD2_k127_4228744_5 bacterial-type flagellum assembly K02421,K03228,K13820 - - 0.000000000000000000000000000000000000000000000000000000000391 226.0
HFD2_k127_4228744_6 Belongs to the bacterial histone-like protein family K05788 - - 0.000000000000000000000000000000000000000000000000000000004596 201.0
HFD2_k127_4228744_7 peptidylprolyl isomerase, FKBP-type K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000009071 158.0
HFD2_k127_4228744_9 Flagellar biosynthetic protein FliQ K02420,K03227 - - 0.00000000000000000000000003064 109.0
HFD2_k127_4287986_0 Domain of unknown function (DUF1732) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005371 361.0
HFD2_k127_4287986_1 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004354 283.0
HFD2_k127_4287986_2 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000000000000000000000000001777 238.0
HFD2_k127_4287986_3 PFAM glycosyl transferase family 9 K02843 - - 0.00000000000000000000000000000000000000000113 169.0
HFD2_k127_4287986_4 Belongs to the UPF0434 family K09791 - - 0.0000000000000000009833 93.0
HFD2_k127_4287986_5 - - - - 0.000000000001779 67.0
HFD2_k127_4287986_6 - - - - 0.0000000007394 63.0
HFD2_k127_4292619_0 ATP-binding region ATPase domain protein K03407,K13490 - 2.7.13.3 1.4e-265 842.0
HFD2_k127_4292619_1 Methyl-accepting chemotaxis protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 433.0
HFD2_k127_4292619_2 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000006066 148.0
HFD2_k127_4422424_0 metalloendopeptidase activity K08602 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 422.0
HFD2_k127_4422424_1 Responsible for synthesis of pseudouridine from uracil K06179,K06180 - 5.4.99.23,5.4.99.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 318.0
HFD2_k127_4422424_3 CoA binding domain K06929 - - 0.00000000000000000000000000000000000000000000000000000000000000684 218.0
HFD2_k127_4422424_5 Regulatory protein, FmdB family - - - 0.000000000000000000000496 98.0
HFD2_k127_4422424_6 Protein of unknown function (DUF3667) - - - 0.00000000000000001698 91.0
HFD2_k127_4434639_0 ABC transporter C-terminal domain K06158 - - 5.435e-287 894.0
HFD2_k127_4434639_1 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 6.139e-282 878.0
HFD2_k127_4434639_10 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005912 314.0
HFD2_k127_4434639_11 PFAM Mammalian cell entry related domain protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000001124 231.0
HFD2_k127_4434639_12 energy transducer activity K03832 - - 0.000000000000000000000000000000000000000000000000001259 205.0
HFD2_k127_4434639_14 mechanosensitive ion channel activity K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.0000000000000000000000000000000000000000001107 164.0
HFD2_k127_4434639_15 ABC-type transport auxiliary lipoprotein component K18480 - - 0.00000000000000000000000000000000007794 146.0
HFD2_k127_4434639_16 ATP-independent chaperone mediated protein folding - - - 0.00000000000000000000000000000008767 145.0
HFD2_k127_4434639_19 - - - - 0.0000000000000004317 79.0
HFD2_k127_4434639_2 Glutamate synthase K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005783 565.0
HFD2_k127_4434639_20 - - - - 0.000000000000002221 85.0
HFD2_k127_4434639_3 Major Facilitator Superfamily K08177 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 497.0
HFD2_k127_4434639_4 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 421.0
HFD2_k127_4434639_5 HAMP domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006287 436.0
HFD2_k127_4434639_6 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006141 394.0
HFD2_k127_4434639_7 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003884 387.0
HFD2_k127_4434639_8 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 364.0
HFD2_k127_4434639_9 Abc transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 380.0
HFD2_k127_4444006_0 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007433 381.0
HFD2_k127_4444006_1 Metallophosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006799 294.0
HFD2_k127_4444006_2 PFAM Cytochrome c, class I - - - 0.00000000000000000000000000000000000000000000000003512 190.0
HFD2_k127_4444006_4 YCII-related domain - - - 0.0000000000000000000000002596 121.0
HFD2_k127_4444006_5 PFAM cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.0000000000000001145 93.0
HFD2_k127_4445527_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 1.782e-256 797.0
HFD2_k127_4445527_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 3.458e-231 721.0
HFD2_k127_4445527_10 negative regulation of translational initiation - - - 0.000000000000000000000000000000000000000000000000000000000000000001425 229.0
HFD2_k127_4445527_11 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000000000000000000000000000000001243 219.0
HFD2_k127_4445527_12 Histidine kinase - - - 0.00000000000000000000000000000000000000000003222 177.0
HFD2_k127_4445527_13 deoxyhypusine monooxygenase activity - - - 0.000000000000000000000000000000000000000003 179.0
HFD2_k127_4445527_14 - - - - 0.000000000821 62.0
HFD2_k127_4445527_15 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000009906 58.0
HFD2_k127_4445527_16 PFAM Activator of Hsp90 ATPase 1 family protein - - - 0.0000001319 53.0
HFD2_k127_4445527_17 SMART Rhodanese domain protein - - - 0.00000419 49.0
HFD2_k127_4445527_18 AraC type K13529 - 3.2.2.21 0.0003683 45.0
HFD2_k127_4445527_2 homoserine dehydrogenase K00003 - 1.1.1.3 3.282e-214 681.0
HFD2_k127_4445527_3 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 574.0
HFD2_k127_4445527_4 HB1, ASXL, restriction endonuclease HTH domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 562.0
HFD2_k127_4445527_5 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004761 531.0
HFD2_k127_4445527_6 PFAM Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 317.0
HFD2_k127_4445527_7 YceI-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000182 257.0
HFD2_k127_4445527_9 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000001154 231.0
HFD2_k127_4445616_0 ABC transporter K06147,K06148 - - 7.863e-256 795.0
HFD2_k127_4445616_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000005388 178.0
HFD2_k127_4457682_0 AAA domain K10742 - 3.6.4.12 7.419e-289 899.0
HFD2_k127_4457682_1 Acid phosphatase homologues - - - 0.000000000000000000000000000000000000000000000000000006486 199.0
HFD2_k127_4457682_2 Smr domain - - - 0.0000000000000001726 82.0
HFD2_k127_4457682_3 RNase_H superfamily K07502 - - 0.0000000000000256 74.0
HFD2_k127_4464898_0 Histone deacetylase domain - - - 6.701e-239 749.0
HFD2_k127_4464898_1 Mur ligase family, catalytic domain K02558 - 6.3.2.45 4.667e-236 766.0
HFD2_k127_4464898_2 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 7.603e-223 693.0
HFD2_k127_4464898_3 beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 426.0
HFD2_k127_4464898_4 LD-carboxypeptidase K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 387.0
HFD2_k127_4464898_5 8 heme-binding sites - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 345.0
HFD2_k127_4464898_6 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000000005918 183.0
HFD2_k127_4464898_7 - - - - 0.00000000000000002324 95.0
HFD2_k127_4470605_0 COG2015, Alkyl sulfatase and related hydrolases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 397.0
HFD2_k127_4470605_1 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000004376 127.0
HFD2_k127_4470605_2 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000003075 115.0
HFD2_k127_4470605_3 Phospholipid methyltransferase - - - 0.0000000162 59.0
HFD2_k127_4524872_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004753 618.0
HFD2_k127_4524872_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002971 422.0
HFD2_k127_4524872_2 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007371 326.0
HFD2_k127_4524872_3 cysteine-type peptidase activity K13695 - - 0.0000000000000000000000000000000000002321 153.0
HFD2_k127_4524872_4 Helix-hairpin-helix motif K02237 - - 0.00000000000000000000000000219 129.0
HFD2_k127_4524872_5 Pfam:DUF2029 - - - 0.000000000000000000000002816 117.0
HFD2_k127_4574688_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.0 1020.0
HFD2_k127_4574688_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 5.557e-249 782.0
HFD2_k127_4574688_10 2 iron, 2 sulfur cluster binding K13643 - - 0.000000000000000002941 96.0
HFD2_k127_4574688_11 - - - - 0.0003309 53.0
HFD2_k127_4574688_2 Cytochrome c - - - 5.343e-206 648.0
HFD2_k127_4574688_3 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 393.0
HFD2_k127_4574688_4 N-terminal half of MaoC dehydratase K09709,K18291 - 4.2.1.153,4.2.1.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006566 323.0
HFD2_k127_4574688_5 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 301.0
HFD2_k127_4574688_6 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000003033 218.0
HFD2_k127_4574688_7 Cytochrome C oxidase subunit II, periplasmic domain K00376 - 1.7.2.4 0.00000000000000000000000000000000000000000000000000000000183 220.0
HFD2_k127_4574688_8 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.000000000000000000000000000000000000000000000000000000006121 214.0
HFD2_k127_4574688_9 Pyruvate phosphate dikinase - - - 0.00000000000000000000000000000000000000000000000000000006929 204.0
HFD2_k127_4575753_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 4.781e-279 864.0
HFD2_k127_4575753_1 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007769 608.0
HFD2_k127_4575753_10 Sigma-70, region 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003617 257.0
HFD2_k127_4575753_11 RDD family - - - 0.00000000000000000000000000000000000000000000000000000000000000006972 226.0
HFD2_k127_4575753_12 MerR HTH family regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000004184 224.0
HFD2_k127_4575753_13 Belongs to the SUA5 family K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000001609 209.0
HFD2_k127_4575753_14 DNA-templated transcription, initiation K03088,K11333 - 1.3.7.14,1.3.7.15 0.00000000000000000000000000000000000000000000000004059 192.0
HFD2_k127_4575753_15 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000004505 157.0
HFD2_k127_4575753_17 peptidyl-tyrosine sulfation - - - 0.00000000000001284 88.0
HFD2_k127_4575753_2 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 582.0
HFD2_k127_4575753_3 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008923 567.0
HFD2_k127_4575753_4 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 518.0
HFD2_k127_4575753_5 protein kinase activity K08884 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 499.0
HFD2_k127_4575753_6 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 418.0
HFD2_k127_4575753_7 PFAM permease YjgP YjgQ family protein K11720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 383.0
HFD2_k127_4575753_8 PFAM permease YjgP YjgQ family protein K07091 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005632 366.0
HFD2_k127_4575753_9 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000009668 263.0
HFD2_k127_4577189_0 Tetratricopeptide repeat - - - 5.019e-258 863.0
HFD2_k127_4577189_1 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004849 628.0
HFD2_k127_4577189_10 - - - - 0.00000000000000000000000000000000000000000003264 177.0
HFD2_k127_4577189_12 cyclic nucleotide binding K00384,K04739,K07001,K10914 - 1.8.1.9 0.000000000000000000000000000000000000002321 164.0
HFD2_k127_4577189_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 504.0
HFD2_k127_4577189_3 protein trimerization - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 383.0
HFD2_k127_4577189_4 uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 338.0
HFD2_k127_4577189_5 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009251 341.0
HFD2_k127_4577189_6 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 323.0
HFD2_k127_4577189_7 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 310.0
HFD2_k127_4577189_8 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000003168 245.0
HFD2_k127_4577189_9 polysaccharide export K01991 - - 0.0000000000000000000000000000000000000000000000000000009126 219.0
HFD2_k127_4697094_0 PFAM glycosyl transferase family 51 K05366 - 2.4.1.129,3.4.16.4 0.0 1220.0
HFD2_k127_4697094_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 8.369e-243 768.0
HFD2_k127_4697094_10 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000003573 237.0
HFD2_k127_4697094_11 Ubiquinol-cytochrome C reductase - - - 0.000000000000000000000000000000000000000000962 162.0
HFD2_k127_4697094_12 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03117 - - 0.0000000000000000000000000001502 120.0
HFD2_k127_4697094_13 Tetratricopeptide repeat - - - 0.0000000000000000000000000001654 129.0
HFD2_k127_4697094_14 - - - - 0.000000001274 68.0
HFD2_k127_4697094_2 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009392 595.0
HFD2_k127_4697094_3 Mediates influx of magnesium ions K03284,K16074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006324 520.0
HFD2_k127_4697094_4 Exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005627 494.0
HFD2_k127_4697094_5 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 472.0
HFD2_k127_4697094_6 epoxide hydrolase K01253 - 3.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004815 405.0
HFD2_k127_4697094_7 Thiol disulfide interchange protein dsbA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 388.0
HFD2_k127_4697094_8 Thiolase, C-terminal domain K00626,K07508 - 2.3.1.16,2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003392 402.0
HFD2_k127_4697094_9 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000985 341.0
HFD2_k127_47633_0 FAD linked oxidase domain protein - - - 0.0 1695.0
HFD2_k127_47633_1 Pyruvate flavodoxin ferredoxin K00174 - 1.2.7.11,1.2.7.3 3.408e-302 937.0
HFD2_k127_47633_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 9.228e-263 841.0
HFD2_k127_47633_3 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005781 294.0
HFD2_k127_47633_4 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.000000000000000000000000000000000000000000000000000006505 194.0
HFD2_k127_47633_5 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000003133 199.0
HFD2_k127_47633_6 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000004968 114.0
HFD2_k127_47633_7 YtxH-like protein - - - 0.0005025 51.0
HFD2_k127_4808696_0 RNA polymerase recycling family C-terminal K03580 - - 0.0 1156.0
HFD2_k127_4808696_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620,K00930 - 2.3.1.1,2.3.1.35,2.7.2.8 0.0 1077.0
HFD2_k127_4808696_10 regulation of single-species biofilm formation K13573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 423.0
HFD2_k127_4808696_11 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 379.0
HFD2_k127_4808696_12 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042,K18121 - 1.1.1.31,1.1.1.60,1.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 369.0
HFD2_k127_4808696_13 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145,K05829 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004001 310.0
HFD2_k127_4808696_14 Protein of unknown function (DUF1054) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009615 250.0
HFD2_k127_4808696_16 Regulates arginine biosynthesis genes K03402 - - 0.000000000000000000000000000000000000000001033 179.0
HFD2_k127_4808696_17 Response regulator, receiver K03413 - - 0.00000000000000000000000000000000000000002286 158.0
HFD2_k127_4808696_19 PFAM Hemerythrin HHE cation binding domain K07216 - - 0.000000000000000000000000003927 115.0
HFD2_k127_4808696_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 9.263e-272 848.0
HFD2_k127_4808696_3 Domain of unknown function (DUF4388) - - - 1.877e-200 643.0
HFD2_k127_4808696_4 Histidine kinase - - - 1.409e-199 634.0
HFD2_k127_4808696_5 Belongs to the peptidase M16 family K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005821 634.0
HFD2_k127_4808696_6 PFAM peptidase M20 K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003795 558.0
HFD2_k127_4808696_7 Amidohydrolase family K05603 - 3.5.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003241 528.0
HFD2_k127_4808696_8 regulation of single-species biofilm formation K13572,K13573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005776 449.0
HFD2_k127_4808696_9 Flavin containing amine oxidoreductase K01854 - 5.4.99.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 431.0
HFD2_k127_4831325_0 Peptidase family M49 - - - 1.315e-221 701.0
HFD2_k127_4831325_1 Voltage gated chloride channel K03281 - - 3.31e-198 637.0
HFD2_k127_4831325_2 Protein of unknown function (DUF1295) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006751 262.0
HFD2_k127_4831325_3 PFAM Short-chain dehydrogenase reductase SDR K07124 - - 0.0000000000000000000000000000000000000000000000000000000000000004854 239.0
HFD2_k127_4831325_4 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.00000000000000000000000000000000000000000000000000000002335 203.0
HFD2_k127_4831325_6 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000000002249 165.0
HFD2_k127_4831325_7 Belongs to the ompA family K03640 - - 0.0000000000000000000000003952 113.0
HFD2_k127_4834840_0 7TM receptor with intracellular HD hydrolase K07037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 466.0
HFD2_k127_4834840_1 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000001594 223.0
HFD2_k127_4834840_2 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000000000000000000002968 178.0
HFD2_k127_4846693_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007177 303.0
HFD2_k127_4846693_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000005278 233.0
HFD2_k127_4846693_2 tRNA nucleotidyltransferase domain 2 putative K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000002344 87.0
HFD2_k127_4850459_0 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 289.0
HFD2_k127_4850459_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.000000000000000000000000000000000000000000000000000005316 193.0
HFD2_k127_4850459_2 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.000000000000000000007817 92.0
HFD2_k127_4871969_0 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 1.555e-223 700.0
HFD2_k127_4871969_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 3.617e-207 661.0
HFD2_k127_4871969_10 Nucleoside recognition K06373 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004284 256.0
HFD2_k127_4871969_11 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.000000000000000000000000000000000000000000000000000000000000000000003039 236.0
HFD2_k127_4871969_12 Glyoxalase-like domain K05606 - 5.1.99.1 0.00000000000000000000000000000000000000000000000000000000000009775 241.0
HFD2_k127_4871969_13 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.000000000000000000000000000000000000000000000000000000000001187 218.0
HFD2_k127_4871969_14 OsmC-like protein K09136 - - 0.000000000000000000000000000000000000000000000004823 183.0
HFD2_k127_4871969_15 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000006692 150.0
HFD2_k127_4871969_16 Epimerase dehydratase - - - 0.000000000000000000000001534 118.0
HFD2_k127_4871969_2 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008115 607.0
HFD2_k127_4871969_3 PFAM transglutaminase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009338 514.0
HFD2_k127_4871969_4 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 479.0
HFD2_k127_4871969_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 432.0
HFD2_k127_4871969_6 endonuclease activity K07451 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005391 403.0
HFD2_k127_4871969_7 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 363.0
HFD2_k127_4871969_8 Domain of unknown function (DUF2437) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000916 373.0
HFD2_k127_4871969_9 membrane protein required for spore maturation in B.subtilis K06374 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001979 258.0
HFD2_k127_4888724_0 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 6.397e-197 629.0
HFD2_k127_4888724_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 599.0
HFD2_k127_4888724_10 Glycosyltransferase family 87 - - - 0.00003497 57.0
HFD2_k127_4888724_2 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008487 530.0
HFD2_k127_4888724_3 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 417.0
HFD2_k127_4888724_4 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 433.0
HFD2_k127_4888724_5 Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate K00598 - 2.1.1.144 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004096 324.0
HFD2_k127_4888724_6 hydrolase activity, acting on ester bonds K07051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 296.0
HFD2_k127_4888724_7 Methyl-transferase K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000001921 288.0
HFD2_k127_4888724_8 Methyl-transferase K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000001146 241.0
HFD2_k127_4888724_9 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000001235 190.0
HFD2_k127_490988_0 PFAM PHP domain protein K02347,K04477 - - 1.981e-248 780.0
HFD2_k127_490988_1 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 536.0
HFD2_k127_490988_2 BON domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000304 256.0
HFD2_k127_490988_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001983 231.0
HFD2_k127_490988_4 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000000000000000000000000000000000000000000000461 215.0
HFD2_k127_490988_5 Universal stress protein - - - 0.000000000000000000000000000000000000004729 150.0
HFD2_k127_490988_7 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000001123 61.0
HFD2_k127_491508_0 PFAM Three-deoxy-D-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 2.08e-210 663.0
HFD2_k127_491508_1 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003816 451.0
HFD2_k127_491508_2 PFAM glycosyl transferase family 9 K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 432.0
HFD2_k127_491508_3 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000497 435.0
HFD2_k127_491508_4 PHP domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007408 397.0
HFD2_k127_491508_5 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 340.0
HFD2_k127_491508_6 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 0.0000000000001462 71.0
HFD2_k127_491508_7 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.000003076 60.0
HFD2_k127_497_0 4-alpha-glucanotransferase K00705 - 2.4.1.25 1.856e-230 724.0
HFD2_k127_497_1 ATPase family associated with various cellular activities (AAA) K06027 - 3.6.4.6 3.037e-230 725.0
HFD2_k127_497_10 phosphohistidine phosphatase, SixA K08296 - - 0.0000000000000000000000000001399 133.0
HFD2_k127_497_12 cytochrome c - - - 0.00000000000000000000000001469 117.0
HFD2_k127_497_13 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000002765 97.0
HFD2_k127_497_14 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.000000000000000000062 104.0
HFD2_k127_497_15 Protein of unknown function (DUF3341) - - - 0.00000000001349 72.0
HFD2_k127_497_16 - - - - 0.00000000001795 78.0
HFD2_k127_497_2 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 2.692e-194 625.0
HFD2_k127_497_3 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003804 637.0
HFD2_k127_497_4 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000912 583.0
HFD2_k127_497_5 Belongs to the arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 504.0
HFD2_k127_497_6 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01885,K01894 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002663 501.0
HFD2_k127_497_7 Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 460.0
HFD2_k127_497_8 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) K06169 - - 0.000000000000000000000000000000000000000000000000000000000000000000004331 239.0
HFD2_k127_497_9 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000000000000004505 217.0
HFD2_k127_5026930_0 chaperone-mediated protein folding K21007 - - 1.038e-220 707.0
HFD2_k127_5026930_1 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008669 550.0
HFD2_k127_5026930_10 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000002917 146.0
HFD2_k127_5026930_12 cytochrome oxidase assembly K02259 - - 0.000000000000000000000001097 117.0
HFD2_k127_5026930_13 Protein of unknown function (FYDLN_acid) - - - 0.000000000000000002025 101.0
HFD2_k127_5026930_2 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 447.0
HFD2_k127_5026930_3 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 374.0
HFD2_k127_5026930_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007686 384.0
HFD2_k127_5026930_6 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001121 234.0
HFD2_k127_5026930_7 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000006979 235.0
HFD2_k127_5026930_8 Protein of unknown function (DUF420) K08976 - - 0.000000000000000000000000000000000000000000000000002058 191.0
HFD2_k127_5026930_9 - - - - 0.0000000000000000000000000000000000000000000000003996 181.0
HFD2_k127_5053978_0 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 1.429e-231 743.0
HFD2_k127_5053978_1 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 1.393e-220 694.0
HFD2_k127_5053978_10 Response regulator receiver domain K03413 - - 0.000000000000000000000000000000000000000000000000000000000000000008826 226.0
HFD2_k127_5053978_11 chemotaxis K03410 GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896,GO:0050918 - 0.00000000000000000000000000000000000000000000000000005663 213.0
HFD2_k127_5053978_12 Biopolymer transport protein ExbD/TolR - - - 0.000000000000000000000000000000000000000000000000003043 186.0
HFD2_k127_5053978_13 chemotaxis K02659,K03408 - - 0.000000000000000000000000000000000000000000003998 178.0
HFD2_k127_5053978_2 PFAM ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 615.0
HFD2_k127_5053978_3 Belongs to the LarC family K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 533.0
HFD2_k127_5053978_5 AIR carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 391.0
HFD2_k127_5053978_6 MotA/TolQ/ExbB proton channel family K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 336.0
HFD2_k127_5053978_7 Biopolymer transport protein ExbD/TolR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006413 278.0
HFD2_k127_5053978_8 histidine kinase HAMP region domain protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001869 250.0
HFD2_k127_5053978_9 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000002731 242.0
HFD2_k127_5077710_0 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488 GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009156,GO:0009161,GO:0009163,GO:0009164,GO:0009165,GO:0009167,GO:0009168,GO:0009987,GO:0015949,GO:0015950,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0032261,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0043173,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 569.0
HFD2_k127_5077710_1 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003944 408.0
HFD2_k127_5077710_2 COG1064 Zn-dependent alcohol K12957 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006703 377.0
HFD2_k127_5077710_3 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 370.0
HFD2_k127_5077710_4 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008649 307.0
HFD2_k127_5077710_6 - - - - 0.0000000000000000000000000000000000000000002616 163.0
HFD2_k127_514670_0 Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005187 563.0
HFD2_k127_514670_1 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 451.0
HFD2_k127_514670_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 298.0
HFD2_k127_514670_3 peptidase m48, ste24p - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001557 295.0
HFD2_k127_514670_4 Domain of unknown function (DUF4175) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002899 263.0
HFD2_k127_514670_6 - - - - 0.00000000000000000000000000000001785 133.0
HFD2_k127_515365_0 Aerotolerance regulator N-terminal - - - 3.366e-252 812.0
HFD2_k127_515365_1 Domain of unknown function (DUF4175) - - - 1.208e-224 717.0
HFD2_k127_515365_2 phosphorelay signal transduction system - - - 7.567e-203 647.0
HFD2_k127_515365_3 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004302 557.0
HFD2_k127_515365_4 ATPase associated with various cellular activities K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009757 544.0
HFD2_k127_515365_5 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005766 543.0
HFD2_k127_515365_6 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005273 462.0
HFD2_k127_515365_7 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005325 430.0
HFD2_k127_520057_0 ABC transporter K02017 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 465.0
HFD2_k127_520057_1 Binding-protein-dependent transport system inner membrane component K02018 - - 0.0000000000000000000000000000000000000000000000000000000000000000004812 246.0
HFD2_k127_520057_2 TIGRFAM molybdenum ABC transporter, periplasmic K02020 - - 0.000000000000000000000000000000000000000000000000000000000000000007062 235.0
HFD2_k127_520057_3 response to heat K07090 - - 0.0000000000000000000000002482 108.0
HFD2_k127_520057_4 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000001 74.0
HFD2_k127_525937_0 Peptidase family M50 K11749 - - 2.637e-217 687.0
HFD2_k127_525937_1 Belongs to the peptidase M50B family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 557.0
HFD2_k127_525937_11 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000001221 143.0
HFD2_k127_525937_12 GIY-YIG catalytic domain K07461 - - 0.0000000000000000000000001987 108.0
HFD2_k127_525937_13 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.0000000000000817 73.0
HFD2_k127_525937_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 547.0
HFD2_k127_525937_3 Domain of unknown function (DUF1731) K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 380.0
HFD2_k127_525937_4 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 364.0
HFD2_k127_525937_5 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006098 351.0
HFD2_k127_525937_6 Glycoprotease family K01409,K14742 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007027 321.0
HFD2_k127_525937_7 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 315.0
HFD2_k127_525937_8 channel protein, hemolysin III family K11068 - - 0.0000000000000000000000000000000000000000000000000000000000000000001401 239.0
HFD2_k127_525937_9 alginic acid biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000003136 218.0
HFD2_k127_5263226_0 Cysteine-rich domain K00113 - 1.1.5.3 1.703e-237 741.0
HFD2_k127_5263226_1 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003791 602.0
HFD2_k127_5263226_10 - - - - 0.0000000000000000000000000003894 125.0
HFD2_k127_5263226_11 - - - - 0.0000000000000000007971 98.0
HFD2_k127_5263226_3 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003247 435.0
HFD2_k127_5263226_4 transmembrane signaling receptor activity K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 423.0
HFD2_k127_5263226_5 transmembrane signaling receptor activity K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004555 303.0
HFD2_k127_5263226_6 Flagellar Motor Protein K02557 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004982 267.0
HFD2_k127_5263226_7 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001141 251.0
HFD2_k127_5263226_8 Protein of unknown function (DUF3501) - - - 0.000000000000000000000000000000000000000000000000000000000000000004308 252.0
HFD2_k127_5263226_9 Adenylylsulfate kinase K00860 - 2.7.1.25 0.00000000000000000000000000000000000000000000000000000002061 216.0
HFD2_k127_5274968_0 Glycosyl hydrolase 36 superfamily, catalytic domain K00702,K13688 - 2.4.1.20 0.0 1100.0
HFD2_k127_5285098_0 Class III cytochrome C family - - - 1.062e-241 763.0
HFD2_k127_5285098_1 DegT/DnrJ/EryC1/StrS aminotransferase family K13010,K19430 - 2.6.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 625.0
HFD2_k127_5285098_10 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003681 360.0
HFD2_k127_5285098_11 PPIC-type PPIASE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003183 359.0
HFD2_k127_5285098_12 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007421 342.0
HFD2_k127_5285098_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004598 330.0
HFD2_k127_5285098_14 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009805 308.0
HFD2_k127_5285098_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001591 291.0
HFD2_k127_5285098_16 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006541 281.0
HFD2_k127_5285098_17 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003921 257.0
HFD2_k127_5285098_18 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000008908 241.0
HFD2_k127_5285098_19 COG0463 Glycosyltransferases involved in cell wall biogenesis K13002 - - 0.0000000000000000000000000000000000000000000000000000000000000059 243.0
HFD2_k127_5285098_20 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000001582 227.0
HFD2_k127_5285098_21 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000003094 216.0
HFD2_k127_5285098_22 Glycosyl transferase family 2 K00721,K00786 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000006498 231.0
HFD2_k127_5285098_23 Putative bacterial lipoprotein (DUF799) - - - 0.00000000000000000000000000000000000000000000000000000754 205.0
HFD2_k127_5285098_24 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000007688 160.0
HFD2_k127_5285098_25 acetyltransferase K03789 - 2.3.1.128 0.00000000000000000000000000000000001301 143.0
HFD2_k127_5285098_26 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000002996 143.0
HFD2_k127_5285098_27 - - - - 0.000000000000000000000000000001819 141.0
HFD2_k127_5285098_28 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000001774 134.0
HFD2_k127_5285098_29 methyltransferase - - - 0.0000000000000001012 92.0
HFD2_k127_5285098_3 cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 517.0
HFD2_k127_5285098_31 Uncharacterized conserved protein (DUF2304) K09153 - - 0.0000004655 57.0
HFD2_k127_5285098_32 COG3063 Tfp pilus assembly protein PilF K02656 - - 0.0004991 53.0
HFD2_k127_5285098_4 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006635 464.0
HFD2_k127_5285098_5 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 428.0
HFD2_k127_5285098_6 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008003 381.0
HFD2_k127_5285098_7 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 357.0
HFD2_k127_5285098_8 PFAM Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003669 370.0
HFD2_k127_5285098_9 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002701 365.0
HFD2_k127_5287846_0 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840,K15778 - 5.4.2.2,5.4.2.8 2.763e-234 734.0
HFD2_k127_5287846_1 Mannose-6-phosphate isomerase K00971 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002914 550.0
HFD2_k127_5287846_2 PFAM ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 359.0
HFD2_k127_5287846_3 Biopolymer transport protein ExbD TolR K03559 - - 0.000000000000000000000000000000000000000000004935 167.0
HFD2_k127_5287846_4 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00000000000000000000000000002832 132.0
HFD2_k127_5287846_5 MotA TolQ ExbB proton channel K03561 - - 0.0000000001803 62.0
HFD2_k127_5293004_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.764e-212 665.0
HFD2_k127_5293004_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005833 415.0
HFD2_k127_5293004_2 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000001619 214.0
HFD2_k127_5299855_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0 1168.0
HFD2_k127_5299855_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 5.587e-230 729.0
HFD2_k127_5299855_10 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006218 292.0
HFD2_k127_5299855_11 Bacterial regulatory proteins, tetR family K16137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003778 263.0
HFD2_k127_5299855_12 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000007197 249.0
HFD2_k127_5299855_13 XdhC Rossmann domain K07402 - - 0.00000000000000000000000000000000000000000000000000000000000009683 228.0
HFD2_k127_5299855_14 MobA-Related Protein K07141 - 2.7.7.76 0.00000000000000000000000000000000000000000000000000000000471 206.0
HFD2_k127_5299855_15 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000000000000000321 209.0
HFD2_k127_5299855_16 oxidoreductase activity, acting on CH-OH group of donors K09386 - - 0.000000000000000000000000000000000000000000000000009361 186.0
HFD2_k127_5299855_17 - - - - 0.00000000000000000000000000000000000000002172 175.0
HFD2_k127_5299855_18 XdhC and CoxI family - - - 0.00000000000000000000000000000000000002061 155.0
HFD2_k127_5299855_19 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000001723 129.0
HFD2_k127_5299855_2 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 525.0
HFD2_k127_5299855_20 NifU-like N terminal domain K04488 - - 0.000000000000000000000000002168 126.0
HFD2_k127_5299855_21 4 iron, 4 sulfur cluster binding K00176 - 1.2.7.3 0.0000000000001934 77.0
HFD2_k127_5299855_23 YCII-related domain - - - 0.00000000002275 64.0
HFD2_k127_5299855_3 AAA domain (dynein-related subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 445.0
HFD2_k127_5299855_4 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 426.0
HFD2_k127_5299855_5 Protein of unknown function (DUF475) K09799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004819 416.0
HFD2_k127_5299855_6 Transcriptional regulator, LysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006205 393.0
HFD2_k127_5299855_7 VWA domain containing CoxE-like protein K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006296 391.0
HFD2_k127_5299855_8 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006031 362.0
HFD2_k127_5299855_9 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003366 311.0
HFD2_k127_5303364_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 1.397e-223 702.0
HFD2_k127_5303364_1 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007894 556.0
HFD2_k127_5303364_10 GDP-mannose mannosyl hydrolase activity K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000004032 176.0
HFD2_k127_5303364_11 - - - - 0.000000000000000000000002177 108.0
HFD2_k127_5303364_12 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.000000000000005964 82.0
HFD2_k127_5303364_13 Helix-turn-helix domain - - - 0.000000002046 64.0
HFD2_k127_5303364_2 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009101 550.0
HFD2_k127_5303364_3 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000699 536.0
HFD2_k127_5303364_4 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 490.0
HFD2_k127_5303364_5 TIGRFAM galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 440.0
HFD2_k127_5303364_6 transcriptional regulator K09017,K18301 - - 0.00000000000000000000000000000000000000000000000000000000000000000001226 239.0
HFD2_k127_5303364_7 Conserved protein containing a Zn-ribbon-like motif possibly RNA-binding - - - 0.0000000000000000000000000000000000000000000000000000000006889 207.0
HFD2_k127_5303364_8 ISFtu1 transposase K01152 - - - 0.000000000000000000000000000000000000000000000000004645 190.0
HFD2_k127_5303364_9 deoxyribonuclease V activity K05982 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0034641,GO:0043170,GO:0043737,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.21.7 0.000000000000000000000000000000000000000000000001165 196.0
HFD2_k127_5312592_0 Peptidogalycan biosysnthesis/recognition K09919 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005587 527.0
HFD2_k127_5312592_1 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 539.0
HFD2_k127_5312592_10 Aminotransferase class I and II K11358 - 2.6.1.1 0.000000000000000000000000000004603 124.0
HFD2_k127_5312592_11 ketosteroid isomerase - - - 0.00000000008992 72.0
HFD2_k127_5312592_2 N,N-dimethylaniline monooxygenase activity K07222 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006282 427.0
HFD2_k127_5312592_3 PFAM Pyruvate flavodoxin ferredoxin oxidoreductase K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004996 389.0
HFD2_k127_5312592_4 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009409 355.0
HFD2_k127_5312592_5 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 323.0
HFD2_k127_5312592_6 PFAM Thiamine pyrophosphate K00170,K00187 - 1.2.7.1,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006903 323.0
HFD2_k127_5312592_7 Cys-tRNA(Pro) hydrolase activity K19055 - - 0.000000000000000000000000000000000000000000000000000001437 195.0
HFD2_k127_5312592_8 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.00000000000000000000000000000000000000001221 162.0
HFD2_k127_5312592_9 Protein of unknown function (DUF2845) - - - 0.000000000000000000000000000000000000005646 161.0
HFD2_k127_5354795_0 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 345.0
HFD2_k127_5354795_1 Protein similar to CwfJ C-terminus 1 K19710 - 2.7.7.53 0.0000000000000000000000000000000000000000000000000000000000000000000000006866 248.0
HFD2_k127_5373770_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006407 483.0
HFD2_k127_5373770_1 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 395.0
HFD2_k127_5373770_2 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 368.0
HFD2_k127_5373770_3 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 336.0
HFD2_k127_5378720_0 protein related to plant photosystem II stability assembly factor - - - 4.737e-197 619.0
HFD2_k127_5378720_1 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 299.0
HFD2_k127_5378720_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003169 252.0
HFD2_k127_5378720_3 ThiS family K03636 - - 0.0000000000000000000000000003236 129.0
HFD2_k127_5378720_4 cytochrome complex assembly - - - 0.000000000000000000000001973 109.0
HFD2_k127_5378720_5 - - - - 0.00000000000001273 76.0
HFD2_k127_5380924_0 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 391.0
HFD2_k127_5380924_1 OPT oligopeptide transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007444 330.0
HFD2_k127_5382987_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 462.0
HFD2_k127_5382987_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 345.0
HFD2_k127_5387109_0 AcrB/AcrD/AcrF family - - - 0.0 1031.0
HFD2_k127_5387109_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 7.402e-238 752.0
HFD2_k127_5387109_10 PAP2 superfamily C-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005413 269.0
HFD2_k127_5387109_11 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.0000000000000000000000000000000000000000000000000000000000000000006735 234.0
HFD2_k127_5387109_12 OmpA family K02557 - - 0.00000000000000000000000000000000000000000000000000000000000000004697 234.0
HFD2_k127_5387109_13 OmpA family K02557 - - 0.0000000000000000000000000000000000000000000000000000003158 204.0
HFD2_k127_5387109_14 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000001308 118.0
HFD2_k127_5387109_15 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000005935 119.0
HFD2_k127_5387109_16 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000004102 106.0
HFD2_k127_5387109_17 Outer membrane efflux protein - - - 0.0000000000607 78.0
HFD2_k127_5387109_18 E1-E2 ATPase K17686 - 3.6.3.54 0.00000174 51.0
HFD2_k127_5387109_2 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006034 486.0
HFD2_k127_5387109_3 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004205 441.0
HFD2_k127_5387109_5 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 370.0
HFD2_k127_5387109_6 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 365.0
HFD2_k127_5387109_7 TRAP transporter T-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 353.0
HFD2_k127_5387109_8 thiolester hydrolase activity K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002843 318.0
HFD2_k127_5387109_9 Uracil DNA glycosylase superfamily K03648 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004715 288.0
HFD2_k127_5389834_0 PFAM AMP-dependent synthetase and ligase K12429,K18662 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0051087 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009727 527.0
HFD2_k127_5389834_1 ABC-type branched-chain amino acid transport K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 512.0
HFD2_k127_5389834_2 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 385.0
HFD2_k127_5389834_3 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000002079 217.0
HFD2_k127_5406573_0 Aldehyde dehydrogenase family K00129 - 1.2.1.5 1.628e-227 717.0
HFD2_k127_5406573_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004127 502.0
HFD2_k127_5406573_2 DNA-binding transcription factor activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 480.0
HFD2_k127_5406573_3 ADP-ribosylation factor family K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 411.0
HFD2_k127_5406573_4 Alkyl hydroperoxide reductase K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000001658 231.0
HFD2_k127_5406573_5 protein conserved in bacteria K09927 - - 0.000000000000000000000000000000000000000000000000000000000000000002843 229.0
HFD2_k127_5406573_6 Belongs to the Dps family K04047 - - 0.00000000000000000000000000000000000006962 154.0
HFD2_k127_5406573_7 PFAM helix-turn-helix domain protein - - - 0.0000000000000000000000000001307 115.0
HFD2_k127_5406788_0 peptidyl-tyrosine sulfation - - - 0.0 2155.0
HFD2_k127_5406788_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0 1275.0
HFD2_k127_5406788_10 ZIP Zinc transporter K16267 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004213 357.0
HFD2_k127_5406788_12 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008057 335.0
HFD2_k127_5406788_13 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 307.0
HFD2_k127_5406788_14 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000001531 292.0
HFD2_k127_5406788_15 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005244 273.0
HFD2_k127_5406788_16 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000000016 248.0
HFD2_k127_5406788_17 - - - - 0.00000000000000000000000000000000000000000005348 170.0
HFD2_k127_5406788_19 sequence-specific DNA binding K03557,K07712 GO:0000018,GO:0000229,GO:0000785,GO:0000786,GO:0000787,GO:0000789,GO:0000976,GO:0000984,GO:0000985,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001121,GO:0001130,GO:0001131,GO:0001140,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008301,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016032,GO:0016070,GO:0018130,GO:0019042,GO:0019045,GO:0019046,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031421,GO:0032359,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0042803,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044374,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044427,GO:0044444,GO:0044446,GO:0044464,GO:0044815,GO:0045892,GO:0045893,GO:0045911,GO:0045934,GO:0045935,GO:0046483,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000002179 155.0
HFD2_k127_5406788_2 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 6.61e-230 726.0
HFD2_k127_5406788_20 Prokaryotic diacylglycerol kinase K00901 - 2.7.1.107 0.000000000000000000000000007478 116.0
HFD2_k127_5406788_22 methyltransferase - - - 0.00000000000002716 81.0
HFD2_k127_5406788_23 Cytochrome c K00406,K08906 - - 0.00000375 57.0
HFD2_k127_5406788_3 Efflux ABC transporter, permease ATP-binding protein K06147 - - 1.066e-222 704.0
HFD2_k127_5406788_4 glutamate--cysteine ligase K01919 - 6.3.2.2 3.509e-212 671.0
HFD2_k127_5406788_5 Transglycosylase SLT domain K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 565.0
HFD2_k127_5406788_6 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007331 508.0
HFD2_k127_5406788_7 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 523.0
HFD2_k127_5406788_8 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004085 508.0
HFD2_k127_5406788_9 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006697 346.0
HFD2_k127_5416625_0 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 448.0
HFD2_k127_5416625_1 Serine Threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 391.0
HFD2_k127_5416625_2 4-Oxalocrotonate Tautomerase - - - 0.0000000000000000000000000000000000000000000000000000000001397 207.0
HFD2_k127_5416625_3 - - - - 0.0000000000000000000000000000000000000000000202 176.0
HFD2_k127_5423121_0 to the hyi family K01816 - 5.3.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 336.0
HFD2_k127_5423121_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000414 199.0
HFD2_k127_5423121_2 Cytochrome P460 - - - 0.00000000000000000001218 99.0
HFD2_k127_5423121_3 Redoxin K03564 - 1.11.1.15 0.000000007366 66.0
HFD2_k127_5432874_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 3.361e-204 642.0
HFD2_k127_5432874_1 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 377.0
HFD2_k127_5432874_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000002433 159.0
HFD2_k127_5432874_3 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.00000002278 66.0
HFD2_k127_5439417_0 D-isomer specific 2-hydroxyacid dehydrogenase K00058,K16843 - 1.1.1.310,1.1.1.399,1.1.1.95 7.073e-243 760.0
HFD2_k127_5439417_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 3.587e-209 700.0
HFD2_k127_5439417_2 Cation transporting ATPase, C-terminus K01531 - 3.6.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003293 541.0
HFD2_k127_5439417_3 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006905 489.0
HFD2_k127_5439417_4 Carbohydrate family 9 binding domain-like - - - 0.000000000000000000000000000000000000000000005417 178.0
HFD2_k127_5439417_5 histone H2A K63-linked ubiquitination K03466 - - 0.000000000000000000000000000000000000002514 159.0
HFD2_k127_5439417_6 Tetratricopeptide repeat - - - 0.00000000000000000000000000001033 131.0
HFD2_k127_5439417_7 - - - - 0.000000000000000000000000002253 130.0
HFD2_k127_5446142_0 TrkA-C domain K03455 - - 5.076e-233 741.0
HFD2_k127_5446142_1 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 7.527e-200 698.0
HFD2_k127_5446142_10 Double sensory domain of two-component sensor kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004416 362.0
HFD2_k127_5446142_11 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 365.0
HFD2_k127_5446142_12 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 358.0
HFD2_k127_5446142_13 PGAP1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005291 293.0
HFD2_k127_5446142_14 ErfK YbiS YcfS YnhG family protein K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004961 293.0
HFD2_k127_5446142_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004034 261.0
HFD2_k127_5446142_16 PFAM amino acid-binding ACT domain protein - - - 0.000000000000000000000000000000000000000000000000000001722 195.0
HFD2_k127_5446142_17 Bacterial protein of unknown function (DUF882) - - - 0.0000000000000000000000000000000000000004636 155.0
HFD2_k127_5446142_18 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.0000000000000000000000000000001 146.0
HFD2_k127_5446142_2 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 524.0
HFD2_k127_5446142_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007985 458.0
HFD2_k127_5446142_4 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 452.0
HFD2_k127_5446142_5 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 462.0
HFD2_k127_5446142_6 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 449.0
HFD2_k127_5446142_7 tRNA nucleotidyltransferase domain 2 putative K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009461 427.0
HFD2_k127_5446142_8 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003928 415.0
HFD2_k127_5446142_9 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate K00019 - 1.1.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 367.0
HFD2_k127_5446833_0 Selenocysteine-specific translation elongation factor K03833 - - 1.44e-297 937.0
HFD2_k127_5446833_1 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 6.577e-297 924.0
HFD2_k127_5446833_10 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006784 440.0
HFD2_k127_5446833_11 Outer membrane efflux protein K12543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 394.0
HFD2_k127_5446833_12 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 381.0
HFD2_k127_5446833_13 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008696 381.0
HFD2_k127_5446833_14 GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006611 377.0
HFD2_k127_5446833_15 Transcriptional regulatory protein, C terminal K07658 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004881 324.0
HFD2_k127_5446833_16 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000488 284.0
HFD2_k127_5446833_17 Phosphoribosyl transferase domain K07101 - - 0.0000000000000000000000000000000000000000000000000000000000000000003591 238.0
HFD2_k127_5446833_19 phosphorelay signal transduction system - - - 0.0000000000000000000001795 102.0
HFD2_k127_5446833_2 GAF domain - - - 3.078e-279 898.0
HFD2_k127_5446833_3 Proton-conducting membrane transporter K00342 - 1.6.5.3 7.177e-257 800.0
HFD2_k127_5446833_4 response regulator K07713 - - 2.597e-216 679.0
HFD2_k127_5446833_5 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 1.528e-197 628.0
HFD2_k127_5446833_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 611.0
HFD2_k127_5446833_7 zinc-ribbon domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007767 635.0
HFD2_k127_5446833_8 GDP-mannose 4,6 dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 507.0
HFD2_k127_5446833_9 Acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005051 456.0
HFD2_k127_5451956_0 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 1.374e-211 661.0
HFD2_k127_5451956_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 1.071e-210 679.0
HFD2_k127_5451956_10 Mediates influx of magnesium ions K03284,K16074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003689 381.0
HFD2_k127_5451956_11 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006149 350.0
HFD2_k127_5451956_12 PQQ enzyme repeat K17713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005775 343.0
HFD2_k127_5451956_13 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004294 335.0
HFD2_k127_5451956_14 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 303.0
HFD2_k127_5451956_15 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004247 299.0
HFD2_k127_5451956_16 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000138 271.0
HFD2_k127_5451956_17 MerR, DNA binding K19591 - - 0.0000000000000000000000000000000000000000000000000000002661 199.0
HFD2_k127_5451956_18 protein trimerization K15368 - - 0.000000000000000000000000000000000000000000000000000001531 200.0
HFD2_k127_5451956_19 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0000000000000000000000000000000000001675 150.0
HFD2_k127_5451956_2 acyl-coa dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 570.0
HFD2_k127_5451956_20 - - - - 0.0000000000000000000000000000271 124.0
HFD2_k127_5451956_22 CHRD domain - - - 0.00000000000000000000001815 110.0
HFD2_k127_5451956_4 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003175 520.0
HFD2_k127_5451956_5 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 507.0
HFD2_k127_5451956_6 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 477.0
HFD2_k127_5451956_7 ArgK protein K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 469.0
HFD2_k127_5451956_8 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 469.0
HFD2_k127_5451956_9 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 439.0
HFD2_k127_5455863_0 Belongs to the FtsK SpoIIIE SftA family K03466 - - 0.0 1031.0
HFD2_k127_5455863_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.482e-309 967.0
HFD2_k127_5455863_10 zinc-ribbon domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002405 285.0
HFD2_k127_5455863_11 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000599 267.0
HFD2_k127_5455863_12 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000004744 188.0
HFD2_k127_5455863_13 acetyltransferase - - - 0.00000000000000000000000000000000000000000000001911 192.0
HFD2_k127_5455863_14 Protein of unknown function (DUF1232) - - - 0.00000000000000000000000000000000000000000000003594 190.0
HFD2_k127_5455863_15 Transcription factor zinc-finger K09981 - - 0.00000000000000000000000000000000001098 154.0
HFD2_k127_5455863_16 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.0000000000000000000000000000001138 143.0
HFD2_k127_5455863_17 thiolester hydrolase activity - - - 0.000000000000000000000000002681 126.0
HFD2_k127_5455863_18 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000001229 116.0
HFD2_k127_5455863_19 protein import - - - 0.0000000000000000000000000271 124.0
HFD2_k127_5455863_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 6.697e-228 719.0
HFD2_k127_5455863_20 - - - - 0.000000000000000000000001871 114.0
HFD2_k127_5455863_22 - - - - 0.000000000189 70.0
HFD2_k127_5455863_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 3.873e-225 732.0
HFD2_k127_5455863_4 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008391 537.0
HFD2_k127_5455863_5 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 490.0
HFD2_k127_5455863_6 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 469.0
HFD2_k127_5455863_7 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 376.0
HFD2_k127_5455863_8 DAHP synthetase I family K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000997 354.0
HFD2_k127_5455863_9 Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA K00556 - 2.1.1.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006294 330.0
HFD2_k127_5463276_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 8.371e-220 687.0
HFD2_k127_5463276_1 Asparagine synthase - - - 0.0000000000000000000000000000000000000000000000148 194.0
HFD2_k127_54940_0 single-stranded-DNA-specific exonuclease RecJ K07462 - - 6.9e-243 758.0
HFD2_k127_54940_1 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008724 565.0
HFD2_k127_54940_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 506.0
HFD2_k127_54940_3 Ribosomal protein L11 methyltransferase (PrmA) K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000002115 242.0
HFD2_k127_54940_4 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000000003107 202.0
HFD2_k127_54940_5 Thioesterase superfamily - - - 0.0000000000000000000000000000000000001249 162.0
HFD2_k127_54940_6 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000095 55.0
HFD2_k127_5503008_0 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 2.563e-290 921.0
HFD2_k127_5503008_1 General secretory system II, protein E domain protein K02454 - - 2.262e-222 692.0
HFD2_k127_5503008_2 ATPase family associated with various cellular activities (AAA) - - - 2.389e-219 709.0
HFD2_k127_5503008_3 acetyl-CoA hydrolase K18118 - 2.8.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 592.0
HFD2_k127_5503008_4 Inositol monophosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 368.0
HFD2_k127_5503008_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007487 306.0
HFD2_k127_5503008_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001862 266.0
HFD2_k127_5503008_7 Domain of unknown function (DUF4386) - - - 0.00000000000000000000000000000000001248 151.0
HFD2_k127_5503008_8 Uncharacterized conserved protein (DUF2277) - - - 0.00000000000000000000003646 106.0
HFD2_k127_5503008_9 lyase activity - - - 0.00000000000002057 72.0
HFD2_k127_5508949_0 Penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 0.0 1102.0
HFD2_k127_5508949_1 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 4.733e-225 717.0
HFD2_k127_5508949_10 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.000000000000000000000000000000000000000000000006685 179.0
HFD2_k127_5508949_12 - - - - 0.0000000000000000000000005133 107.0
HFD2_k127_5508949_13 Beta-ketoacyl synthase K04786 - - 0.00000000000000003565 90.0
HFD2_k127_5508949_14 domain, Protein - - - 0.00000000002646 71.0
HFD2_k127_5508949_2 Histidine kinase K13598 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008924 610.0
HFD2_k127_5508949_3 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 507.0
HFD2_k127_5508949_4 Phosphotransferase enzyme family K02204 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 449.0
HFD2_k127_5508949_5 TPR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009125 424.0
HFD2_k127_5508949_6 dipeptide transport K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 340.0
HFD2_k127_5508949_7 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 289.0
HFD2_k127_5508949_8 protein trimerization - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001066 289.0
HFD2_k127_5543990_0 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 - - 2.187e-300 942.0
HFD2_k127_5543990_1 Chemotaxis protein histidine kinase and related kinases K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009309 531.0
HFD2_k127_5543990_10 Is able to transfer iron-sulfur clusters to apo- ferredoxin. Multiple cycles of 2Fe2S cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system K13628 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009058,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0016530,GO:0018130,GO:0019438,GO:0019538,GO:0022607,GO:0031163,GO:0031974,GO:0033013,GO:0033014,GO:0034641,GO:0034986,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0051604,GO:0070013,GO:0071704,GO:0071840,GO:0097428,GO:0140104,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000002178 187.0
HFD2_k127_5543990_11 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896 3.5.1.44 0.00000000000000000000000000000000000000000000000004791 195.0
HFD2_k127_5543990_12 Ferredoxin K04755 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0006790,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016043,GO:0016226,GO:0016491,GO:0022607,GO:0022900,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0055114,GO:0071840 - 0.000000000000000000000000000000000000000007686 155.0
HFD2_k127_5543990_14 Fe-S assembly protein IscX - GO:0003674,GO:0004857,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0030234,GO:0031163,GO:0043086,GO:0043167,GO:0043169,GO:0044085,GO:0044092,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050790,GO:0051186,GO:0065007,GO:0065009,GO:0071840,GO:0098772 - 0.00000000000000000000000000000009819 126.0
HFD2_k127_5543990_16 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.0000000000000002711 79.0
HFD2_k127_5543990_2 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006747 432.0
HFD2_k127_5543990_3 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009646 400.0
HFD2_k127_5543990_4 histidine kinase HAMP region domain protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004411 349.0
HFD2_k127_5543990_5 ABC transporter substrate binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000111 249.0
HFD2_k127_5543990_6 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000000000000000000000000000000001079 216.0
HFD2_k127_5543990_7 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000002472 206.0
HFD2_k127_5543990_8 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000001007 198.0
HFD2_k127_5543990_9 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051604,GO:0071704,GO:0097428,GO:1901564,GO:1902494,GO:1990230,GO:1990234 - 0.00000000000000000000000000000000000000000000000000001576 205.0
HFD2_k127_5549848_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.0 1015.0
HFD2_k127_5549848_1 Ribosomal protein S1-like RNA-binding domain K02945 - - 4.903e-198 636.0
HFD2_k127_5549848_10 Protein of unknown function (DUF971) K03593 - - 0.000000000000000000000000000000000000000002564 161.0
HFD2_k127_5549848_12 Domain of unknown function (DUF4388) K12132 - 2.7.11.1 0.000000000000000000000004867 105.0
HFD2_k127_5549848_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 541.0
HFD2_k127_5549848_3 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 454.0
HFD2_k127_5549848_4 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 404.0
HFD2_k127_5549848_5 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007967 376.0
HFD2_k127_5549848_6 Deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 328.0
HFD2_k127_5549848_7 PFAM metal-dependent phosphohydrolase, HD sub domain K01524,K06950 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004427 338.0
HFD2_k127_5549848_8 Transport and Golgi organisation 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062 303.0
HFD2_k127_5549848_9 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000000000000000000004755 222.0
HFD2_k127_5577593_0 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008218 490.0
HFD2_k127_5577593_1 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003113 240.0
HFD2_k127_56671_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 4.732e-243 785.0
HFD2_k127_56671_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 2.047e-221 702.0
HFD2_k127_56671_11 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 392.0
HFD2_k127_56671_12 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 386.0
HFD2_k127_56671_13 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009984 314.0
HFD2_k127_56671_14 PFAM 4Fe-4S - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 296.0
HFD2_k127_56671_15 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001128 293.0
HFD2_k127_56671_16 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001233 256.0
HFD2_k127_56671_17 PFAM peptidase M52 hydrogen uptake protein K03605 - - 0.0000000000000000000000000000000000000000000000000000000004471 206.0
HFD2_k127_56671_18 DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000000000000000000006488 214.0
HFD2_k127_56671_19 Response regulator, receiver - - - 0.00000000000000000000000000000000003744 140.0
HFD2_k127_56671_2 TonB dependent receptor K02014 - - 1.681e-211 691.0
HFD2_k127_56671_20 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000008518 132.0
HFD2_k127_56671_21 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.000000000000000000000000000000001233 145.0
HFD2_k127_56671_22 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.000000000000000000000000000000005319 131.0
HFD2_k127_56671_24 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.00000000000000000000000002979 111.0
HFD2_k127_56671_25 Alpha beta hydrolase - - - 0.000000000000000000000000233 117.0
HFD2_k127_56671_26 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000002123 104.0
HFD2_k127_56671_27 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.0000000000001188 82.0
HFD2_k127_56671_28 Domain of unknown function (DUF4395) - - - 0.000000000003755 75.0
HFD2_k127_56671_29 TonB C terminal K03832 - - 0.0000000001073 76.0
HFD2_k127_56671_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 3.516e-206 692.0
HFD2_k127_56671_4 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 579.0
HFD2_k127_56671_5 PFAM V-type ATPase 116 kDa K02123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 565.0
HFD2_k127_56671_6 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 477.0
HFD2_k127_56671_7 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 453.0
HFD2_k127_56671_8 Uncharacterised MFS-type transporter YbfB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004424 449.0
HFD2_k127_56671_9 PFAM Major facilitator superfamily K08224 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 428.0
HFD2_k127_5697938_0 protein conserved in bacteria K09930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003707 411.0
HFD2_k127_5697938_1 endonuclease activity K07451 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 411.0
HFD2_k127_5697938_10 - - - - 0.000000000000614 72.0
HFD2_k127_5697938_11 Putative zinc-finger - - - 0.0000001069 63.0
HFD2_k127_5697938_2 Glycosyl hydrolase 36 superfamily, catalytic domain K00702,K13688 - 2.4.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 374.0
HFD2_k127_5697938_3 regulation of single-species biofilm formation K13572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 362.0
HFD2_k127_5697938_4 regulation of single-species biofilm formation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003816 318.0
HFD2_k127_5697938_6 Putative DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001155 252.0
HFD2_k127_5697938_7 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.0000000000000000000000000000000000000000000000000000000000001019 224.0
HFD2_k127_5697938_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000002361 239.0
HFD2_k127_5697938_9 COGs COG2148 Sugar transferase involved in lipopolysaccharide synthesis - - - 0.000000000000004053 89.0
HFD2_k127_5765673_0 PFAM Prolyl oligopeptidase family - - - 2.111e-275 861.0
HFD2_k127_5765673_1 Putative modulator of DNA gyrase K03568 - - 4.047e-250 787.0
HFD2_k127_5765673_10 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.0000000000000000000000001525 110.0
HFD2_k127_5765673_12 endonuclease activity K07451 - - 0.00007821 53.0
HFD2_k127_5765673_2 Putative modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007384 591.0
HFD2_k127_5765673_3 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 449.0
HFD2_k127_5765673_4 endonuclease activity K07451 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 342.0
HFD2_k127_5765673_5 TAP-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005866 354.0
HFD2_k127_5765673_7 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000001069 190.0
HFD2_k127_5765673_9 - - - - 0.000000000000000000000000000001473 124.0
HFD2_k127_5827583_0 asparaginyl-tRNA synthetase K01893 - 6.1.1.22 1.947e-258 806.0
HFD2_k127_5827583_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 2.519e-236 736.0
HFD2_k127_5827583_10 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 370.0
HFD2_k127_5827583_11 riboflavin synthase, alpha K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 315.0
HFD2_k127_5827583_12 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002404 246.0
HFD2_k127_5827583_14 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000503 222.0
HFD2_k127_5827583_15 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000001662 239.0
HFD2_k127_5827583_16 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000000000000000000000000000162 214.0
HFD2_k127_5827583_17 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000000000000008893 175.0
HFD2_k127_5827583_18 Chemotaxis protein CheY K03413 - - 0.00000000000000000000000000000000000000001467 171.0
HFD2_k127_5827583_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 4.195e-224 706.0
HFD2_k127_5827583_20 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000000006789 158.0
HFD2_k127_5827583_21 OmpA family K03286 - - 0.000000000000000000000000000000000002558 156.0
HFD2_k127_5827583_22 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.000000000000000000000000009655 109.0
HFD2_k127_5827583_24 Membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.0000000000002621 74.0
HFD2_k127_5827583_25 Beta-1,3-glucanase - - - 0.0000000000003364 83.0
HFD2_k127_5827583_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 1.526e-206 649.0
HFD2_k127_5827583_4 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 1.917e-206 672.0
HFD2_k127_5827583_5 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007808 512.0
HFD2_k127_5827583_6 PBS lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006247 435.0
HFD2_k127_5827583_7 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 380.0
HFD2_k127_5827583_8 TIGRFAM intracellular protease, PfpI family K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 355.0
HFD2_k127_5827583_9 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007636 338.0
HFD2_k127_5832652_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 2.254e-257 800.0
HFD2_k127_5832652_1 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 465.0
HFD2_k127_5832652_10 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000000000000000000000000000000000000000001106 231.0
HFD2_k127_5832652_11 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000000000000000000000000000000000000000000000004681 200.0
HFD2_k127_5832652_12 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000000000000000000000000000007646 142.0
HFD2_k127_5832652_2 repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004906 436.0
HFD2_k127_5832652_3 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005367 432.0
HFD2_k127_5832652_4 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 354.0
HFD2_k127_5832652_5 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005216 320.0
HFD2_k127_5832652_6 chloride channel K03281 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 304.0
HFD2_k127_5832652_7 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001258 275.0
HFD2_k127_5832652_8 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001128 251.0
HFD2_k127_5832652_9 chromosome segregation K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002208 245.0
HFD2_k127_5855105_0 Glycosyltransferase family 28 N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003205 342.0
HFD2_k127_5869737_0 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 451.0
HFD2_k127_5869737_1 Belongs to the MenA family. Type 1 subfamily K02548 GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046428,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 2.5.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 428.0
HFD2_k127_5869737_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008234 274.0
HFD2_k127_5869737_3 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000001029 190.0
HFD2_k127_5869737_4 Carbon monoxide dehydrogenase subunit G (CoxG) - - - 0.00000000000000000000000000000000000002151 167.0
HFD2_k127_5869737_5 Putative cyclase K07130 - 3.5.1.9 0.0000000000000000000000001954 114.0
HFD2_k127_5869737_6 PFAM acyl-CoA dehydrogenase domain protein - - - 0.000000000000005751 85.0
HFD2_k127_5896078_0 Cytochrome C biogenesis protein transmembrane region K04084 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 606.0
HFD2_k127_5896078_1 Serine Threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004216 578.0
HFD2_k127_5896078_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 367.0
HFD2_k127_5896078_4 GLTT repeat (6 copies) - - - 0.0000000000000001303 90.0
HFD2_k127_590911_0 4Fe-4S dicluster domain K18930 - - 0.0 1224.0
HFD2_k127_590911_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1126.0
HFD2_k127_590911_10 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 370.0
HFD2_k127_590911_11 histone H2A K63-linked ubiquitination - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007102 347.0
HFD2_k127_590911_12 SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004869 336.0
HFD2_k127_590911_13 PFAM Cysteine-rich domain K18928 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003666 338.0
HFD2_k127_590911_14 Forkhead associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 299.0
HFD2_k127_590911_15 Protein of unknown function (DUF2400) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001404 264.0
HFD2_k127_590911_16 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000000000000000000000000000000000000000000000007657 206.0
HFD2_k127_590911_17 Thiamine-binding protein - - - 0.00000000000000000000000000000000000000000000884 173.0
HFD2_k127_590911_18 LUD domain K00782 - - 0.00000000000000000000000000000000000000000001536 184.0
HFD2_k127_590911_19 endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000007446 151.0
HFD2_k127_590911_2 lysine 2,3-aminomutase K01843 - 5.4.3.2 1.989e-220 690.0
HFD2_k127_590911_3 Peptidase dimerisation domain - - - 9.167e-202 642.0
HFD2_k127_590911_4 cluster binding protein K18929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 618.0
HFD2_k127_590911_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007014 567.0
HFD2_k127_590911_6 lysine 2,3-aminomutase K01843 - 5.4.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 545.0
HFD2_k127_590911_7 Diadenylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000423 429.0
HFD2_k127_590911_8 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000704 370.0
HFD2_k127_590911_9 endonuclease activity K07451 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 370.0
HFD2_k127_6035723_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 5.341e-287 904.0
HFD2_k127_6035723_1 Biotin carboxylase C-terminal domain K01941,K01961 - 6.3.4.14,6.3.4.6,6.4.1.2 9.171e-238 747.0
HFD2_k127_6035723_10 Biotin-requiring enzyme - - - 0.0000000000000000000000000000000000000000000000008077 202.0
HFD2_k127_6035723_2 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 603.0
HFD2_k127_6035723_3 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity K12583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 572.0
HFD2_k127_6035723_4 heat shock protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 492.0
HFD2_k127_6035723_5 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 298.0
HFD2_k127_6035723_6 Transposase DDE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 290.0
HFD2_k127_6035723_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002499 280.0
HFD2_k127_6035723_8 Transposase DDE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008988 282.0
HFD2_k127_6035723_9 Pectinacetylesterase - - - 0.000000000000000000000000000000000000000000000000000000000008394 223.0
HFD2_k127_6148143_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1521.0
HFD2_k127_6148143_1 Glycosyl transferase family 21 - - - 2.049e-234 739.0
HFD2_k127_6148143_10 MotA TolQ ExbB proton channel K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 362.0
HFD2_k127_6148143_11 ABC transporter K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 354.0
HFD2_k127_6148143_12 Type II secretion system (T2SS), protein K K02460 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 336.0
HFD2_k127_6148143_13 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 308.0
HFD2_k127_6148143_14 HAD-hyrolase-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002698 290.0
HFD2_k127_6148143_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001218 260.0
HFD2_k127_6148143_16 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001888 272.0
HFD2_k127_6148143_17 haloacid dehalogenase-like hydrolase K08966 - 3.1.3.87 0.0000000000000000000000000000000000000000000000000000000000000000000000002093 255.0
HFD2_k127_6148143_18 Type II secretion system (T2SS), protein J K02459 - - 0.000000000000000000000000000000000000000000000000000000000000001535 235.0
HFD2_k127_6148143_19 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000005633 227.0
HFD2_k127_6148143_2 PFAM chemotaxis sensory transducer - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 605.0
HFD2_k127_6148143_20 Type II secretion system (T2SS), protein M K02462 - - 0.0000000000000000000000000000000000000000000000000000000005522 221.0
HFD2_k127_6148143_21 TonB C terminal K03646,K03832 - - 0.000000000000000000000000000000000000000000000000000000003508 214.0
HFD2_k127_6148143_22 Biopolymer transport protein ExbD/TolR K03560 - - 0.0000000000000000000000000000000000000000000000000000001576 197.0
HFD2_k127_6148143_23 general secretion pathway protein K02456,K02457,K02459,K10927,K12285 - - 0.000000000000000000000000000000000000000000000000000228 195.0
HFD2_k127_6148143_24 Prokaryotic N-terminal methylation motif K02458 - - 0.0000000000000000000000000000000000000002692 166.0
HFD2_k127_6148143_25 general secretion pathway protein G K02456 - - 0.00000000000000000000000000305 111.0
HFD2_k127_6148143_3 Type IV pilus assembly protein PilM; K02461 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009282 586.0
HFD2_k127_6148143_4 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005797 565.0
HFD2_k127_6148143_5 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 528.0
HFD2_k127_6148143_6 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004985 498.0
HFD2_k127_6148143_7 Peptidase family M23 K21471 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004945 419.0
HFD2_k127_6148143_8 Ppx GppA K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004464 396.0
HFD2_k127_6148143_9 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007923 376.0
HFD2_k127_6152818_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 3.846e-247 769.0
HFD2_k127_6152818_1 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 526.0
HFD2_k127_6152818_2 Enoyl-CoA hydratase/isomerase K11264 - 4.1.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 346.0
HFD2_k127_6152818_3 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 345.0
HFD2_k127_6152818_4 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003348 290.0
HFD2_k127_6152818_5 Response regulator, receiver K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000003075 271.0
HFD2_k127_6152818_6 histone H2A K63-linked ubiquitination - - - 0.000000000000000000000000000000001702 139.0
HFD2_k127_6152818_7 Acetyl propionyl-CoA carboxylase alpha subunit K02160 - - 0.000000000000000000000001383 113.0
HFD2_k127_6152818_9 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.0000000000000351 84.0
HFD2_k127_6156895_0 CoA-substrate-specific enzyme activase - - - 0.0 1665.0
HFD2_k127_6156895_1 Acetyl-CoA hydrolase/transferase N-terminal domain - - - 5.597e-220 688.0
HFD2_k127_6156895_10 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.00000000000000000000000000000000000000001218 159.0
HFD2_k127_6156895_11 - - - - 0.00000000000000000000000007154 113.0
HFD2_k127_6156895_12 regulation of microtubule-based process K06990 - - 0.00000000564 65.0
HFD2_k127_6156895_2 Patatin-like phospholipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005339 522.0
HFD2_k127_6156895_3 beta-galactosidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008914 507.0
HFD2_k127_6156895_4 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007375 465.0
HFD2_k127_6156895_5 PFAM Uncharacterised ArCR, COG2043 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 438.0
HFD2_k127_6156895_6 Histidine kinase K15011 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 398.0
HFD2_k127_6156895_7 Bacterial extracellular solute-binding protein K10938 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005391 259.0
HFD2_k127_6156895_8 Rhomboid family K07059 - - 0.00000000000000000000000000000000000000000000000000000000000000000116 252.0
HFD2_k127_6156895_9 response regulator K15012 - - 0.00000000000000000000000000000000000000000000000000000000000000022 232.0
HFD2_k127_6169614_0 Phosphoglucose isomerase K01810 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 5.3.1.9 1.15e-276 858.0
HFD2_k127_6169614_1 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 534.0
HFD2_k127_6169614_10 - K01865 - 5.4.4.1 0.0000000000000000000000001229 112.0
HFD2_k127_6169614_11 MazG-like family - - - 0.000000000000000000001307 106.0
HFD2_k127_6169614_2 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004114 533.0
HFD2_k127_6169614_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 473.0
HFD2_k127_6169614_4 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 389.0
HFD2_k127_6169614_5 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006928 385.0
HFD2_k127_6169614_6 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008031 324.0
HFD2_k127_6169614_7 metal cluster binding K06940 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007474 256.0
HFD2_k127_6169614_8 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.000000000000000000000000000000000000000000000000000001003 195.0
HFD2_k127_6169614_9 - - - - 0.000000000000000000000000000000000002249 154.0
HFD2_k127_6176765_0 SMART helicase c2 K03722 - 3.6.4.12 3.285e-293 912.0
HFD2_k127_6176765_1 Histidine kinase - - - 1.072e-212 681.0
HFD2_k127_6176765_2 histidine kinase HAMP region domain protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 568.0
HFD2_k127_6176765_3 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 368.0
HFD2_k127_6176765_4 Small GTP-binding protein K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003908 357.0
HFD2_k127_6181100_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1348.0
HFD2_k127_6181100_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798,K04076,K13525,K17681 - 3.4.21.53 6.958e-235 760.0
HFD2_k127_6181100_10 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 370.0
HFD2_k127_6181100_11 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006996 356.0
HFD2_k127_6181100_12 hydrogenase 4 membrane K12140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001571 289.0
HFD2_k127_6181100_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001101 244.0
HFD2_k127_6181100_14 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000009749 209.0
HFD2_k127_6181100_15 - - - - 0.00000000000000000000000000000000000000000000001779 189.0
HFD2_k127_6181100_16 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000001326 178.0
HFD2_k127_6181100_17 positive regulation of macromolecule biosynthetic process K03973 - - 0.000000000000000000000000000000000000003839 148.0
HFD2_k127_6181100_2 Proton-conducting membrane transporter K12137 - - 1.803e-230 731.0
HFD2_k127_6181100_20 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000005507 125.0
HFD2_k127_6181100_21 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000003689 111.0
HFD2_k127_6181100_23 Fibronectin type III domain - - - 0.000002686 59.0
HFD2_k127_6181100_24 CHASE2 K01768 - 4.6.1.1 0.00008145 53.0
HFD2_k127_6181100_3 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 7.829e-224 702.0
HFD2_k127_6181100_4 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 7.471e-207 676.0
HFD2_k127_6181100_5 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007853 614.0
HFD2_k127_6181100_6 Proton-conducting membrane transporter K12141 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003702 573.0
HFD2_k127_6181100_7 Serine Threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 579.0
HFD2_k127_6181100_8 COG1335 Amidases related to nicotinamidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 497.0
HFD2_k127_6181100_9 NADH dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004591 417.0
HFD2_k127_6228740_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 3.272e-222 726.0
HFD2_k127_6228740_1 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 547.0
HFD2_k127_6228740_2 Belongs to the radical SAM superfamily. RlmN family K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005902 513.0
HFD2_k127_6228740_3 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000001502 275.0
HFD2_k127_6229506_0 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006011 537.0
HFD2_k127_6229506_1 MacB-like periplasmic core domain K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000536 505.0
HFD2_k127_6229506_2 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 421.0
HFD2_k127_6229506_3 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000942 316.0
HFD2_k127_6229506_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 315.0
HFD2_k127_6229506_5 PFAM Class I peptide chain release factor K15034 - - 0.000000000000000000000000000000000000009365 153.0
HFD2_k127_6245863_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004982 451.0
HFD2_k127_6257061_0 epimerase dehydratase K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009867 368.0
HFD2_k127_6257061_1 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000004899 232.0
HFD2_k127_6257061_2 - - - - 0.000000000000000000000000000000000000000000000167 176.0
HFD2_k127_6257061_3 Membrane - - - 0.0000000000000000000000000000000000000000007078 163.0
HFD2_k127_6257061_4 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000005897 147.0
HFD2_k127_6257061_5 Transcriptional Regulator, AraC family - - - 0.00000000000000000000000000000002911 134.0
HFD2_k127_6257061_7 Phospholipase_D-nuclease N-terminal - - - 0.000000000000002537 82.0
HFD2_k127_6257061_8 Redoxin K03564 - 1.11.1.15 0.00000000000004821 72.0
HFD2_k127_6283944_0 7TM receptor with intracellular HD hydrolase K07037 - - 5.255e-258 819.0
HFD2_k127_6283944_1 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 9.51e-205 661.0
HFD2_k127_6283944_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004879 496.0
HFD2_k127_6283944_3 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000000000000000000000000000000000007868 209.0
HFD2_k127_6283944_4 - - - - 0.000000000000000000000002961 111.0
HFD2_k127_6283944_5 PilZ domain - - - 0.0000000000000000000102 91.0
HFD2_k127_6296073_0 Peptidase family M3 K01392 - 3.4.24.15 1.872e-285 902.0
HFD2_k127_6296073_1 AMP-binding enzyme - - - 2.635e-228 730.0
HFD2_k127_6296073_10 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004467 392.0
HFD2_k127_6296073_11 geranylgeranyl reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 351.0
HFD2_k127_6296073_12 MgtC family K07507 - - 0.000000000000000000000000000000000000000000000000000000000000000000005082 263.0
HFD2_k127_6296073_13 Acid phosphatase homologues - - - 0.0000000000000000000000000000000000000000000000001929 187.0
HFD2_k127_6296073_14 Isoprenylcysteine carboxyl methyltransferase (ICMT) family K16168 - - 0.0000000000000000000000000000000000000000000000003597 203.0
HFD2_k127_6296073_15 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000001169 166.0
HFD2_k127_6296073_16 Histidine kinase - - - 0.0000000000000000000000000000000000007702 160.0
HFD2_k127_6296073_17 chromosome segregation K03497 - - 0.00000000000000000005466 99.0
HFD2_k127_6296073_18 Predicted periplasmic protein (DUF2092) - - - 0.00000000000000001177 94.0
HFD2_k127_6296073_19 Belongs to the ompA family - - - 0.000000000009978 78.0
HFD2_k127_6296073_2 Mitochondrial small ribosomal subunit Rsm22 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 561.0
HFD2_k127_6296073_20 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000001466 77.0
HFD2_k127_6296073_21 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system - - - 0.000000003855 68.0
HFD2_k127_6296073_22 - - - - 0.000000005125 70.0
HFD2_k127_6296073_23 luxR family - - - 0.0000271 53.0
HFD2_k127_6296073_24 Membrane - - - 0.00003192 56.0
HFD2_k127_6296073_25 long-chain fatty acid transporting porin activity - - - 0.0000365 55.0
HFD2_k127_6296073_26 helix_turn_helix, Lux Regulon - - - 0.0003964 53.0
HFD2_k127_6296073_27 energy transducer activity K03832 - - 0.0006342 51.0
HFD2_k127_6296073_3 Chalcone and stilbene synthases, C-terminal domain K16167,K19580 - 2.3.1.233 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 503.0
HFD2_k127_6296073_4 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 494.0
HFD2_k127_6296073_5 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 481.0
HFD2_k127_6296073_6 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 443.0
HFD2_k127_6296073_7 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 436.0
HFD2_k127_6296073_8 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009111 406.0
HFD2_k127_6296073_9 nitric oxide dioxygenase activity K00523,K15983 - 1.14.13.142,1.17.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007731 409.0
HFD2_k127_6316139_0 Carbamoyl-phosphate synthetase ammonia chain K01955 - 6.3.5.5 0.0 1802.0
HFD2_k127_6316139_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0 1099.0
HFD2_k127_6316139_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000002442 255.0
HFD2_k127_6316139_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007895 247.0
HFD2_k127_6316139_4 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000006359 201.0
HFD2_k127_6318145_0 Diguanylate cyclase, GGDEF domain - - - 0.0 1181.0
HFD2_k127_6318145_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1053.0
HFD2_k127_6318145_10 Histidine kinase K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002561 463.0
HFD2_k127_6318145_11 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 400.0
HFD2_k127_6318145_12 Domains REC, sigma54 interaction, HTH8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009039 423.0
HFD2_k127_6318145_13 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 389.0
HFD2_k127_6318145_14 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006127 359.0
HFD2_k127_6318145_15 TIGRFAM Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004589 301.0
HFD2_k127_6318145_16 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005086 316.0
HFD2_k127_6318145_17 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 301.0
HFD2_k127_6318145_18 domain, Protein K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000211 256.0
HFD2_k127_6318145_19 ClpP class periplasmic serine protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000002333 244.0
HFD2_k127_6318145_2 GTP-binding protein K06207 - - 0.0 1052.0
HFD2_k127_6318145_20 Uncharacterized conserved protein (DUF2183) - - - 0.0000000000000000000000000000000000000000000000000000000000000005414 251.0
HFD2_k127_6318145_21 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.00000000000000000000000000000000000000000000000000000002745 203.0
HFD2_k127_6318145_22 - - - - 0.000000000000000000000000000000000000000000000000000003986 213.0
HFD2_k127_6318145_23 iron ion homeostasis - - - 0.00000000000000000000000000000000000000000000000007803 189.0
HFD2_k127_6318145_24 - - - - 0.000000000000000000000000000000000000000000000678 177.0
HFD2_k127_6318145_25 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000003788 172.0
HFD2_k127_6318145_26 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000001454 185.0
HFD2_k127_6318145_27 Involved in the tonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000005676 175.0
HFD2_k127_6318145_28 FecR protein - - - 0.0000000000000000000000000002744 132.0
HFD2_k127_6318145_29 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000005618 108.0
HFD2_k127_6318145_3 acetolactate synthase K01576,K01652 - 2.2.1.6,4.1.1.7 5.036e-297 952.0
HFD2_k127_6318145_30 transposase mutator type - - - 0.000000000000000000000001212 106.0
HFD2_k127_6318145_31 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000001381 73.0
HFD2_k127_6318145_32 transposase mutator type - - - 0.000000000002314 77.0
HFD2_k127_6318145_33 - - - - 0.00000000004425 67.0
HFD2_k127_6318145_34 Protein of unknown function (DUF1566) - - - 0.000000559 61.0
HFD2_k127_6318145_4 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 1.187e-264 825.0
HFD2_k127_6318145_5 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 7.484e-253 793.0
HFD2_k127_6318145_6 long-chain fatty acid transport protein - - - 4.336e-239 817.0
HFD2_k127_6318145_7 Histidine kinase HAMP - - - 9.109e-194 617.0
HFD2_k127_6318145_8 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004967 574.0
HFD2_k127_6351789_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1039.0
HFD2_k127_6351789_1 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000161 267.0
HFD2_k127_6351789_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001037 257.0
HFD2_k127_6351789_3 - - - - 0.00000000000000000000000000000000000000000000000000000001134 217.0
HFD2_k127_6351789_4 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000000000000000002932 212.0
HFD2_k127_6351789_5 Uncharacterised nucleotidyltransferase - - - 0.000000000000000000000000000000161 137.0
HFD2_k127_6351789_6 TfoX N-terminal domain K07343 - - 0.00000000000000000002492 106.0
HFD2_k127_6351789_7 Putative zinc-finger - - - 0.00000007745 65.0
HFD2_k127_6377084_0 PFAM Rh family protein ammonium transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 572.0
HFD2_k127_6377084_1 glutathione transferase activity K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000878 254.0
HFD2_k127_6377084_2 SnoaL-like domain - - - 0.00000000000000001105 84.0
HFD2_k127_6377084_3 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.00000000000000001273 83.0
HFD2_k127_6385847_0 heat shock protein 70 K04043 - - 1.05e-306 967.0
HFD2_k127_6385847_1 Arginosuccinate synthase K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000388 569.0
HFD2_k127_6385847_10 acetylornithine aminotransferase K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000002725 233.0
HFD2_k127_6385847_11 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.00000000000000000000000000000000000000000000000000000000000000002402 246.0
HFD2_k127_6385847_12 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000005688 211.0
HFD2_k127_6385847_13 amine dehydrogenase activity K21449 - - 0.000000000000000000000000000000000000000000000000001488 186.0
HFD2_k127_6385847_14 MaoC like domain - - - 0.00000000000000000000000000000000000000000000001939 189.0
HFD2_k127_6385847_15 Belongs to the peptidase S26 family - - - 0.0000000000000000000000000000002162 141.0
HFD2_k127_6385847_17 PFAM Abortive infection protein K07052 - - 0.0000000000000000000000002571 122.0
HFD2_k127_6385847_18 PFAM ResB family protein K07399 - - 0.000000000000000000002845 110.0
HFD2_k127_6385847_2 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722 511.0
HFD2_k127_6385847_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009268 497.0
HFD2_k127_6385847_4 Male sterility protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 495.0
HFD2_k127_6385847_5 FIST N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009206 411.0
HFD2_k127_6385847_6 heat shock protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 348.0
HFD2_k127_6385847_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004934 278.0
HFD2_k127_6385847_8 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001236 266.0
HFD2_k127_6385847_9 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001313 254.0
HFD2_k127_6407278_0 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000002008 199.0
HFD2_k127_6407278_1 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.000000000000000000000000000000000000000000000000000001091 204.0
HFD2_k127_6407278_2 alpha/beta hydrolase fold K01259 - 3.4.11.5 0.000000000000000000003028 102.0
HFD2_k127_6407278_3 - - - - 0.0000000001217 63.0
HFD2_k127_6432489_0 UvrD/REP helicase N-terminal domain - - - 0.0 1082.0
HFD2_k127_6432489_1 PD-(D/E)XK nuclease superfamily - - - 9.887e-294 940.0
HFD2_k127_6432489_10 Histidine-specific methyltransferase, SAM-dependent K18911 - 2.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000649 239.0
HFD2_k127_6432489_11 TIGRFAM Methylglyoxal synthase K01734 - 4.2.3.3 0.000000000000000000000000000000000000000000000000000000000000000433 250.0
HFD2_k127_6432489_12 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000001029 164.0
HFD2_k127_6432489_13 cold-shock protein K03704 - - 0.000000000000000000000000000000000005823 139.0
HFD2_k127_6432489_14 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.000000000000000000000000000000501 138.0
HFD2_k127_6432489_15 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000004355 67.0
HFD2_k127_6432489_16 ABC transporter K01996 - - 0.0000001811 53.0
HFD2_k127_6432489_2 Methyl-transferase K18912 - 1.14.99.50 3.886e-196 619.0
HFD2_k127_6432489_3 B12 binding domain - - - 2.833e-195 623.0
HFD2_k127_6432489_4 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007734 589.0
HFD2_k127_6432489_5 Di-haem oxidoreductase, putative peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 553.0
HFD2_k127_6432489_6 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 460.0
HFD2_k127_6432489_7 Fatty acid desaturase K00508 - 1.14.19.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 423.0
HFD2_k127_6432489_8 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 361.0
HFD2_k127_6432489_9 PFAM ABC transporter K05847 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003716 302.0
HFD2_k127_6439256_0 Von Willebrand factor type A K07114 - - 0.0 1051.0
HFD2_k127_6439256_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 507.0
HFD2_k127_6439256_10 Glyoxalase-like domain K07032 - - 0.00000000000000000000000000000000000000000000000000003668 206.0
HFD2_k127_6439256_11 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000004172 168.0
HFD2_k127_6439256_2 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007997 462.0
HFD2_k127_6439256_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005121 435.0
HFD2_k127_6439256_4 Alpha/beta hydrolase family K07019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 372.0
HFD2_k127_6439256_5 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005742 372.0
HFD2_k127_6439256_6 Von Willebrand factor type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 303.0
HFD2_k127_6439256_7 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000006928 251.0
HFD2_k127_6439256_8 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000002804 215.0
HFD2_k127_6439256_9 Von Willebrand factor type A K07114 - - 0.000000000000000000000000000000000000000000000000000000001967 217.0
HFD2_k127_6440208_0 Proton-conducting membrane transporter K12137 - - 8.276e-213 687.0
HFD2_k127_6440208_1 Proton-conducting membrane transporter K12141 - - 4.758e-210 661.0
HFD2_k127_6440208_10 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000003043 181.0
HFD2_k127_6440208_11 positive regulation of macromolecule biosynthetic process K03973 - - 0.000000000000000000000000000000000005574 139.0
HFD2_k127_6440208_12 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.000000000000000000000001227 104.0
HFD2_k127_6440208_2 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007609 606.0
HFD2_k127_6440208_3 NADH dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000565 372.0
HFD2_k127_6440208_4 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 379.0
HFD2_k127_6440208_5 Serine Threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008629 334.0
HFD2_k127_6440208_6 hydrogenase 4 membrane K12140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004944 303.0
HFD2_k127_6440208_7 adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000005699 282.0
HFD2_k127_6440208_8 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.0000000000000000000000000000000000000000000000000000000000000000006124 236.0
HFD2_k127_6440208_9 TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000001226 236.0
HFD2_k127_644746_0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit K01844 - 5.4.3.3 3.383e-270 863.0
HFD2_k127_644746_1 Ammonium Transporter Family K03320 - - 1.739e-197 623.0
HFD2_k127_644746_10 Aldo/keto reductase family - - - 0.00000161 56.0
HFD2_k127_644746_2 Pfam:Kce K18013 - 2.3.1.247 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006979 441.0
HFD2_k127_644746_3 Dimerisation domain of d-ornithine 4,5-aminomutase K18011 - 5.4.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009951 406.0
HFD2_k127_644746_4 Thioesterase superfamily K18014 - 4.3.1.14 0.0000000000000000000000000000000000000000000000000000000000002423 217.0
HFD2_k127_644746_6 Belongs to the bacterial histone-like protein family K03530 - - 0.0000000000000000000000000000000000001017 143.0
HFD2_k127_644746_8 FAD binding domain K21401 - 1.3.99.38 0.00000000000000000000003794 112.0
HFD2_k127_644746_9 - - - - 0.0000000000000004964 93.0
HFD2_k127_6450543_0 cytochrome c - GO:0005575,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0017004,GO:0022607,GO:0031224,GO:0034622,GO:0043933,GO:0044085,GO:0044425,GO:0065003,GO:0071840 - 6.28e-270 861.0
HFD2_k127_6450543_1 Malate synthase K01638 - 2.3.3.9 6.519e-241 758.0
HFD2_k127_6450543_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000002726 227.0
HFD2_k127_6450543_2 Flavin containing amine oxidoreductase - - - 5.572e-197 622.0
HFD2_k127_6450543_3 cytochrome c biogenesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 552.0
HFD2_k127_6450543_4 dipeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 541.0
HFD2_k127_6450543_5 NAD(P)H quinone oxidoreductase, PIG3 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008543 529.0
HFD2_k127_6450543_6 IrrE N-terminal-like domain K07110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 499.0
HFD2_k127_6450543_7 OPT oligopeptide transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009978 474.0
HFD2_k127_6450543_8 TIGRFAM acetylornithine and succinylornithine aminotransferase K00821,K05830,K09251 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006598,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009308,GO:0009310,GO:0009445,GO:0009447,GO:0009987,GO:0016740,GO:0016769,GO:0019842,GO:0030170,GO:0033094,GO:0034641,GO:0036094,GO:0042402,GO:0042802,GO:0043167,GO:0043168,GO:0044106,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:0097164,GO:1901363,GO:1901564,GO:1901565,GO:1901575 2.6.1.11,2.6.1.17,2.6.1.82 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 384.0
HFD2_k127_6450543_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008188 277.0
HFD2_k127_6454218_0 Signal transduction histidine kinase - - - 0.0 1018.0
HFD2_k127_6454218_1 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 8.926e-272 846.0
HFD2_k127_6454218_10 PFAM FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 492.0
HFD2_k127_6454218_11 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit K00162 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005721 503.0
HFD2_k127_6454218_12 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00161,K00162,K11381,K21416 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 436.0
HFD2_k127_6454218_13 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00065 - 1.1.1.127 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 383.0
HFD2_k127_6454218_14 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 393.0
HFD2_k127_6454218_15 acetyltransferase component of pyruvate dehydrogenase complex K00627,K00658 - 2.3.1.12,2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007332 381.0
HFD2_k127_6454218_17 Pregnancy-associated plasma protein-A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 323.0
HFD2_k127_6454218_18 Transglycosylase SLT domain K08309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 304.0
HFD2_k127_6454218_19 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005235 256.0
HFD2_k127_6454218_2 Two component, sigma54 specific, transcriptional regulator, Fis family K07712 - - 1.204e-248 773.0
HFD2_k127_6454218_20 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000001886 238.0
HFD2_k127_6454218_21 phosphoribosyltransferase K07100 - - 0.000000000000000000000000000000000000000000000000000000000006342 234.0
HFD2_k127_6454218_22 YhhN family - - - 0.000000000000000000000000000000000000000000000000002071 189.0
HFD2_k127_6454218_25 Cyclin-dependent kinase inhibitor 3 (CDKN3) - - - 0.00000000000000000000000000000008956 130.0
HFD2_k127_6454218_26 Phosphopantetheine attachment site - - - 0.0000000000000004639 91.0
HFD2_k127_6454218_28 Carboxypeptidase regulatory-like domain - - - 0.000000000000009196 87.0
HFD2_k127_6454218_3 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 1.702e-233 753.0
HFD2_k127_6454218_4 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 3.34e-200 635.0
HFD2_k127_6454218_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 610.0
HFD2_k127_6454218_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008215 606.0
HFD2_k127_6454218_7 Major facilitator superfamily MFS_1 K02445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 617.0
HFD2_k127_6454218_8 SMART Tetratricopeptide domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007142 579.0
HFD2_k127_6454218_9 cystathionine gamma-synthase activity K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004293 534.0
HFD2_k127_6481393_0 Elongator protein 3, MiaB family, Radical SAM K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 521.0
HFD2_k127_6481393_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000001161 176.0
HFD2_k127_6481393_2 Methionine synthase K00548 - 2.1.1.13 0.000000000000000008668 98.0
HFD2_k127_6483308_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 2.271e-244 762.0
HFD2_k127_6483308_1 aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 2.293e-202 640.0
HFD2_k127_6483308_10 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 395.0
HFD2_k127_6483308_11 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004594 312.0
HFD2_k127_6483308_12 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 298.0
HFD2_k127_6483308_14 Belongs to the UPF0301 (AlgH) family K07735 - - 0.0000000000000000000000000000000000000000000000000000000000000000001507 235.0
HFD2_k127_6483308_15 HAD-hyrolase-like K06019 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000001356 230.0
HFD2_k127_6483308_16 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000000000000000000000000000000000001431 211.0
HFD2_k127_6483308_17 NUDIX domain - - - 0.00000000000000000000000000000000000000000000004684 195.0
HFD2_k127_6483308_18 Putative inner membrane exporter, YdcZ K09936 - - 0.0000000000000000000000000000000000000000000001592 179.0
HFD2_k127_6483308_19 Domain of unknown function (DUF4440) - - - 0.000000000000000000000000000008882 124.0
HFD2_k127_6483308_2 [isocitrate dehydrogenase (NADP+)] phosphatase activity K00906 GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004721,GO:0004722,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009060,GO:0009987,GO:0015980,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0016999,GO:0017076,GO:0017144,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046487,GO:0050790,GO:0055114,GO:0065007,GO:0065009,GO:0070262,GO:0071704,GO:0072350,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 606.0
HFD2_k127_6483308_20 PFAM thioesterase superfamily K02614 - - 0.0000000000000000000000000003436 133.0
HFD2_k127_6483308_21 Winged helix DNA-binding domain - - - 0.00000000000000000000000001678 114.0
HFD2_k127_6483308_3 4Fe-4S ferredoxin iron-sulfur binding domain protein K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 571.0
HFD2_k127_6483308_4 Alcohol dehydrogenase GroES domain protein K19745 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 474.0
HFD2_k127_6483308_5 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006038 477.0
HFD2_k127_6483308_6 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007213 448.0
HFD2_k127_6483308_7 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005262 411.0
HFD2_k127_6483308_8 PFAM FAD linked oxidase domain protein K00104,K11472 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007901 418.0
HFD2_k127_6483308_9 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 393.0
HFD2_k127_6512669_0 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008559 359.0
HFD2_k127_6512669_1 DnaJ C terminal domain K03686,K05516 - - 0.0000000000000000000000000000000000000000000000000000000000001834 216.0
HFD2_k127_6512669_2 FR47-like protein K03789 - 2.3.1.128 0.000000000000000000000000000000000000000000000000000000001328 203.0
HFD2_k127_6542576_0 nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 494.0
HFD2_k127_6542576_1 exodeoxyribonuclease III K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 374.0
HFD2_k127_6542576_2 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K02337,K14162 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 364.0
HFD2_k127_6542576_3 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553,K14160 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000001033 214.0
HFD2_k127_6542576_4 Thioredoxin K03671 - - 0.00000000000000000000000209 103.0
HFD2_k127_6571645_0 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000001187 58.0
HFD2_k127_6660371_0 protein conserved in bacteria K09927 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003423 280.0
HFD2_k127_6660371_1 oligopeptide transport K03305 - - 0.000000000000000000000000000000000000000000000000000000429 210.0
HFD2_k127_6660371_2 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000002576 194.0
HFD2_k127_6660371_3 Rubrerythrin - - - 0.000000000000000000000000000000000000000000002553 186.0
HFD2_k127_6660371_4 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000000000000003892 170.0
HFD2_k127_6660371_6 - - - - 0.00000000000000000000000000000000000001106 158.0
HFD2_k127_6675528_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0 1076.0
HFD2_k127_6675528_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 1.212e-248 779.0
HFD2_k127_6675528_10 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005081 340.0
HFD2_k127_6675528_11 peptidase M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005532 324.0
HFD2_k127_6675528_12 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004185 310.0
HFD2_k127_6675528_13 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 301.0
HFD2_k127_6675528_14 Alpha/beta hydrolase family K03928 - 3.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 304.0
HFD2_k127_6675528_15 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 315.0
HFD2_k127_6675528_16 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002359 291.0
HFD2_k127_6675528_17 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000004675 255.0
HFD2_k127_6675528_18 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003438 258.0
HFD2_k127_6675528_2 Belongs to the CinA family K03742,K03743 - 3.5.1.42 5.222e-195 639.0
HFD2_k127_6675528_20 - - - - 0.0000000000000000000000000000000000000000000000000000000000000003507 230.0
HFD2_k127_6675528_21 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000003576 222.0
HFD2_k127_6675528_22 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000001757 214.0
HFD2_k127_6675528_23 Protein of unknown function (DUF3467) - - - 0.0000000000000000000000000000000000000089 146.0
HFD2_k127_6675528_24 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.0000000000000000000000000000000000009164 142.0
HFD2_k127_6675528_25 PilZ domain - - - 0.0000000000003514 77.0
HFD2_k127_6675528_3 TonB dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002953 587.0
HFD2_k127_6675528_4 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 473.0
HFD2_k127_6675528_5 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009172 452.0
HFD2_k127_6675528_6 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009433 430.0
HFD2_k127_6675528_7 DnaJ molecular chaperone homology domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 413.0
HFD2_k127_6675528_8 ABC transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 393.0
HFD2_k127_6675528_9 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 368.0
HFD2_k127_6690398_0 alcohol dehydrogenase K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008301 488.0
HFD2_k127_6690398_1 ATPases associated with a variety of cellular activities K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004113 255.0
HFD2_k127_6690398_2 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001776 255.0
HFD2_k127_6690398_4 S-acyltransferase activity K00627 - 2.3.1.12 0.00000000000000000000000005507 109.0
HFD2_k127_6709453_0 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 456.0
HFD2_k127_6709453_1 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 366.0
HFD2_k127_67136_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 541.0
HFD2_k127_67136_1 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000075 471.0
HFD2_k127_67136_10 - - - - 0.000000000002428 80.0
HFD2_k127_67136_11 Putative regulatory protein - - - 0.00000000005176 67.0
HFD2_k127_67136_2 RecQ zinc-binding K03654 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 421.0
HFD2_k127_67136_3 TIGRFAM 6-phosphogluconate dehydrogenase (decarboxylating) K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004313 390.0
HFD2_k127_67136_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 326.0
HFD2_k127_67136_5 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000329 226.0
HFD2_k127_67136_6 - - - - 0.00000000000000000000000000000000000000000000000000000000008107 212.0
HFD2_k127_67136_7 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000313 196.0
HFD2_k127_67136_8 - - - - 0.0000000000000000000000000000000000000000000003464 175.0
HFD2_k127_67136_9 - - - - 0.0000000000000000000000027 109.0
HFD2_k127_6749104_0 Belongs to the glycosyl hydrolase 57 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 580.0
HFD2_k127_6749104_1 of the major facilitator superfamily K08151 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 492.0
HFD2_k127_6913770_0 membrane organization K03641 - - 0.0 1109.0
HFD2_k127_6913770_1 Protein conserved in bacteria K09986 - - 0.000000000000000000000000000000000000000000000001026 178.0
HFD2_k127_7016596_0 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 4.144e-206 656.0
HFD2_k127_7016596_1 nitrite reductase [NAD(P)H] activity K00158,K00363,K03809,K05710 - 1.2.3.3,1.6.5.2,1.7.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 469.0
HFD2_k127_7016596_2 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 418.0
HFD2_k127_7016596_3 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase K00162,K21417 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007586 331.0
HFD2_k127_7016596_4 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000005467 207.0
HFD2_k127_7016596_5 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 GO:0003674,GO:0003824,GO:0004422,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006188,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0052657,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.8 0.000000000000000000000000000000000000000000004367 169.0
HFD2_k127_7019523_0 Metallopeptidase family M24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006002 594.0
HFD2_k127_7019523_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003566 561.0
HFD2_k127_7019523_10 - - - - 0.0000000000000000000000000000000000000006389 156.0
HFD2_k127_7019523_11 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000004324 154.0
HFD2_k127_7019523_12 PFAM regulator of chromosome condensation, RCC1 - - - 0.0000000000000000000000002073 111.0
HFD2_k127_7019523_13 cellulase activity - - - 0.00000000001017 78.0
HFD2_k127_7019523_14 - - - - 0.00000000005932 74.0
HFD2_k127_7019523_15 - - - - 0.00000003757 65.0
HFD2_k127_7019523_17 - - - - 0.0001942 53.0
HFD2_k127_7019523_2 PFAM ATP-binding region, ATPase domain protein K02668,K07708,K07709 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 495.0
HFD2_k127_7019523_3 Two component, sigma54 specific, transcriptional regulator, Fis family K07712,K07714 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 390.0
HFD2_k127_7019523_4 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 340.0
HFD2_k127_7019523_6 Doxx family K15977 - - 0.00000000000000000000000000000000000000000000000000004838 190.0
HFD2_k127_7019523_7 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000000001156 209.0
HFD2_k127_7019523_9 - - - - 0.0000000000000000000000000000000000000000001361 171.0
HFD2_k127_7072641_0 Belongs to the glycosyl hydrolase 57 family - - - 1.973e-308 961.0
HFD2_k127_7072641_1 TIGRFAM galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 591.0
HFD2_k127_7072641_10 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006591 291.0
HFD2_k127_7072641_12 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000008954 244.0
HFD2_k127_7072641_13 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000001735 244.0
HFD2_k127_7072641_15 Binds together with S18 to 16S ribosomal RNA K01754,K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048027,GO:0070181,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 4.3.1.19 0.000000000000000000000000000000000000000000000000000001801 195.0
HFD2_k127_7072641_16 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000267 148.0
HFD2_k127_7072641_17 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.00000000000000000000000000000000000307 141.0
HFD2_k127_7072641_18 Rod shape-determining protein K03569 - - 0.000000000000000000000000000000000003758 138.0
HFD2_k127_7072641_19 Could be involved in septation K06412 GO:0000003,GO:0008150,GO:0019954,GO:0030436,GO:0032502,GO:0043934 - 0.000000000000000006975 87.0
HFD2_k127_7072641_2 Aminotransferase, class V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 590.0
HFD2_k127_7072641_3 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 607.0
HFD2_k127_7072641_4 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005414 498.0
HFD2_k127_7072641_5 of the major facilitator superfamily K08151 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 496.0
HFD2_k127_7072641_6 Dicarboxylate carrier MatC domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 473.0
HFD2_k127_7072641_7 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000581 376.0
HFD2_k127_7072641_8 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004043 369.0
HFD2_k127_7072641_9 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 297.0
HFD2_k127_7110403_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 4.811e-224 696.0
HFD2_k127_7110403_1 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 431.0
HFD2_k127_7110403_10 Transmembrane anti-sigma factor - - - 0.00000000000000002226 93.0
HFD2_k127_7110403_12 - - - - 0.00000000002987 77.0
HFD2_k127_7110403_13 Major facilitator Superfamily - - - 0.00005313 55.0
HFD2_k127_7110403_2 Glucose dehydrogenase C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 379.0
HFD2_k127_7110403_3 RarD protein K05786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 335.0
HFD2_k127_7110403_4 peptidylprolyl isomerase, FKBP-type K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000003236 238.0
HFD2_k127_7110403_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000003961 215.0
HFD2_k127_7110403_6 Spondin_N - - - 0.0000000000000000000000000000000000000003058 161.0
HFD2_k127_7110403_8 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000002295 139.0
HFD2_k127_7110403_9 Dienelactone hydrolase family - - - 0.00000000000000000000000000007991 118.0
HFD2_k127_7164979_0 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 1.776e-314 966.0
HFD2_k127_7164979_1 Bacterial regulatory protein, Fis family K13599 - - 4.15e-235 749.0
HFD2_k127_7164979_2 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 608.0
HFD2_k127_7164979_3 Signal transduction histidine kinase K13598 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 584.0
HFD2_k127_7164979_4 Enoyl-(Acyl carrier protein) reductase K16066 - 1.1.1.381 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 351.0
HFD2_k127_7164979_5 Domain of unknown function (DUF4912) K09942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 304.0
HFD2_k127_7164979_6 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.000000000000000000000000000000000000000005958 175.0
HFD2_k127_7164979_7 - - - - 0.0000000000000000000000000000000004852 139.0
HFD2_k127_7164979_8 - - - - 0.00003909 59.0
HFD2_k127_7175743_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000896 606.0
HFD2_k127_7175743_1 ATPase involved in DNA repair K03546 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008088 543.0
HFD2_k127_7175743_10 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000001524 87.0
HFD2_k127_7175743_2 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 411.0
HFD2_k127_7175743_3 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 372.0
HFD2_k127_7175743_4 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000000000000000000000000000005289 203.0
HFD2_k127_7175743_5 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000001736 201.0
HFD2_k127_7175743_6 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000002634 159.0
HFD2_k127_7175743_7 Belongs to the UPF0102 family K07460 - - 0.000000000000000000000000000000003188 149.0
HFD2_k127_7175743_8 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000204 137.0
HFD2_k127_7175743_9 Belongs to the UPF0109 family K06960 - - 0.000000000000000000000000000324 122.0
HFD2_k127_7183694_0 Glucodextranase, domain N K01178 - 3.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 525.0
HFD2_k127_7183694_1 Short-chain dehydrogenase reductase Sdr K00034,K00059,K03366 - 1.1.1.100,1.1.1.304,1.1.1.47,1.1.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 347.0
HFD2_k127_7211438_0 Putative citrate transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005525 613.0
HFD2_k127_7211438_1 homoserine dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007165 290.0
HFD2_k127_7211438_2 Membrane transport protein K07088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006337 287.0
HFD2_k127_7211438_3 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000463 203.0
HFD2_k127_7211830_0 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.0 1017.0
HFD2_k127_7211830_1 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K11779,K11784,K18285 - 1.21.98.1,2.5.1.120,2.5.1.77 8.731e-211 659.0
HFD2_k127_7211830_10 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000135 293.0
HFD2_k127_7211830_11 Belongs to the GbsR family - - - 0.00000000000000000000000000000000000000000000000000000000000000004862 250.0
HFD2_k127_7211830_12 S-adenosylhomocysteine deaminase activity K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000169 164.0
HFD2_k127_7211830_13 - - - - 0.000000000000000001989 85.0
HFD2_k127_7211830_2 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 2.203e-194 620.0
HFD2_k127_7211830_3 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005304 522.0
HFD2_k127_7211830_4 Pyridoxal-dependent decarboxylase conserved domain K01634 - 4.1.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006365 528.0
HFD2_k127_7211830_5 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 452.0
HFD2_k127_7211830_6 PFAM amidohydrolase K20810 - 3.5.4.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 410.0
HFD2_k127_7211830_7 UbiA prenyltransferase family K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005785 389.0
HFD2_k127_7211830_8 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009034 330.0
HFD2_k127_7211830_9 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000317 339.0
HFD2_k127_7223716_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 2.197e-261 823.0
HFD2_k127_7223716_1 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004976 368.0
HFD2_k127_7266372_0 Putative glutamine amidotransferase - - - 3.5e-323 1004.0
HFD2_k127_7266372_1 HAD-hyrolase-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 406.0
HFD2_k127_7266372_2 Short-chain dehydrogenase reductase SDR K00059,K00076,K00216,K03366,K13774,K18337 - 1.1.1.100,1.1.1.159,1.1.1.173,1.1.1.304,1.1.1.377,1.1.1.378,1.1.1.76,1.3.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 361.0
HFD2_k127_7266372_3 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000002966 146.0
HFD2_k127_7277206_0 pyruvate phosphate dikinase K01006 - 2.7.9.1 0.0 1035.0
HFD2_k127_7277206_1 Cell division protein FtsI penicillin-binding protein 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 465.0
HFD2_k127_7277206_2 Heat shock protein DnaJ domain protein K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 435.0
HFD2_k127_7277206_3 Dihydrodipicolinate reductase, N-terminus K21672 - 1.4.1.12,1.4.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 396.0
HFD2_k127_7277206_4 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000002682 208.0
HFD2_k127_7277206_5 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000805 116.0
HFD2_k127_730235_0 PFAM Xanthine uracil vitamin C permease K06901 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008779 575.0
HFD2_k127_730235_1 Uracil phosphoribosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 449.0
HFD2_k127_730235_2 Prephenate dehydratase K04518,K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007123 398.0
HFD2_k127_730235_3 transmembrane signaling receptor activity K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 339.0
HFD2_k127_730235_4 SMART Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003381 306.0
HFD2_k127_730235_5 PFAM Peptidase M48 - - - 0.00000000000000000000000005353 123.0
HFD2_k127_7375102_0 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005574 432.0
HFD2_k127_7375102_1 deoxyhypusine monooxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 419.0
HFD2_k127_7375102_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 384.0
HFD2_k127_7375102_3 Belongs to the pseudouridine synthase RsuA family K06178,K06182 - 5.4.99.21,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 378.0
HFD2_k127_7375102_4 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 325.0
HFD2_k127_7375102_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005773 260.0
HFD2_k127_7375102_6 Transcriptional regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000001078 229.0
HFD2_k127_7375102_7 - - - - 0.0000000000000000000000000000000000000000000000000000001333 196.0
HFD2_k127_7375102_9 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000002538 68.0
HFD2_k127_7396209_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 8.362e-268 876.0
HFD2_k127_7396209_1 Phosphoglucomutase K01835 - 5.4.2.2 2.392e-239 761.0
HFD2_k127_7396209_10 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 382.0
HFD2_k127_7396209_11 Nad-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 354.0
HFD2_k127_7396209_12 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 320.0
HFD2_k127_7396209_13 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004708 293.0
HFD2_k127_7396209_14 Histidine kinase HAMP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002731 273.0
HFD2_k127_7396209_15 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002804 261.0
HFD2_k127_7396209_16 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000004898 234.0
HFD2_k127_7396209_17 PFAM Acyl-ACP thioesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000001794 254.0
HFD2_k127_7396209_18 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000000000000000000000000000000000000004248 220.0
HFD2_k127_7396209_19 - - - - 0.00000000000000000000000000000000000000000000000000000001602 203.0
HFD2_k127_7396209_2 Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 610.0
HFD2_k127_7396209_20 cobalamin binding K03496,K22491 - - 0.0000000000000000000000000000000000000000000000000008718 195.0
HFD2_k127_7396209_21 adenosine 5'-monophosphoramidase activity - - - 0.000000000000000000000000000000000000000000000001403 182.0
HFD2_k127_7396209_22 FR47-like protein - - - 0.0000000000000000000000000000000000000000000004474 173.0
HFD2_k127_7396209_23 THUMP - - - 0.0000000000000000000000000000000000000000000006633 173.0
HFD2_k127_7396209_24 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000003684 172.0
HFD2_k127_7396209_25 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.0000000000000000000000000000000000000548 144.0
HFD2_k127_7396209_26 - - - - 0.000000000000000000000000001559 124.0
HFD2_k127_7396209_27 - K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.00000000000000000000000001921 123.0
HFD2_k127_7396209_28 cheY-homologous receiver domain - - - 0.00000000000000000005346 95.0
HFD2_k127_7396209_29 Histidine kinase - - - 0.0000000000000000127 97.0
HFD2_k127_7396209_3 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005196 501.0
HFD2_k127_7396209_30 FecR protein - - - 0.00000000000007154 86.0
HFD2_k127_7396209_31 Domain of unknown function (DUF3943) - - - 0.000001613 61.0
HFD2_k127_7396209_32 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000257 50.0
HFD2_k127_7396209_33 PFAM FecR protein - - - 0.000004772 59.0
HFD2_k127_7396209_4 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002689 449.0
HFD2_k127_7396209_5 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 440.0
HFD2_k127_7396209_6 Transcriptional regulator K03717 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 426.0
HFD2_k127_7396209_7 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 401.0
HFD2_k127_7396209_8 Phosphomethylpyrimidine kinase K00941,K14153,K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 372.0
HFD2_k127_7396209_9 PFAM Alpha beta hydrolase K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 365.0
HFD2_k127_7404827_0 repeat protein - - - 0.0 3709.0
HFD2_k127_7404827_1 Tetratricopeptide repeat - - - 0.0 1257.0
HFD2_k127_7404827_10 - - - - 0.00000000000000000000000000000000000001118 149.0
HFD2_k127_7404827_11 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000000000000000002889 150.0
HFD2_k127_7404827_14 - - - - 0.0000007649 56.0
HFD2_k127_7404827_2 FHA domain - - - 7.18e-248 784.0
HFD2_k127_7404827_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008934 616.0
HFD2_k127_7404827_4 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006939 598.0
HFD2_k127_7404827_5 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007559 344.0
HFD2_k127_7404827_6 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005283 288.0
HFD2_k127_7404827_9 PilZ domain K02676 - - 0.000000000000000000000000000000000000000000000000001601 192.0
HFD2_k127_7412084_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 2.707e-235 747.0
HFD2_k127_7412084_1 Putative metal-binding motif - - - 1.013e-229 751.0
HFD2_k127_7412084_2 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 317.0
HFD2_k127_7412084_4 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000002116 243.0
HFD2_k127_7412084_5 protein import - - - 0.0000000000000000000000000000000000000000139 171.0
HFD2_k127_7412084_6 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000009628 168.0
HFD2_k127_7412084_7 - - - - 0.0000000000000000000007787 113.0
HFD2_k127_7418784_0 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 2.581e-296 925.0
HFD2_k127_7418784_1 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 460.0
HFD2_k127_7418784_2 TIGRFAM Molybdopterin-guanine dinucleotide biosynthesis protein B K03753 - - 0.00000000000000000000000000000000000000000000005763 192.0
HFD2_k127_7418784_3 Crp-like helix-turn-helix domain - - - 0.00000000000000000000000000001171 119.0
HFD2_k127_7518755_0 cytochrome C peroxidase - - - 7.279e-204 644.0
HFD2_k127_7518755_1 Methionine synthase K00548 - 2.1.1.13 4.437e-200 635.0
HFD2_k127_7518755_10 (ABC) transporter - - - 0.0000000000000000000000000000000000009929 158.0
HFD2_k127_7518755_12 - - - - 0.0002075 48.0
HFD2_k127_7518755_2 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003201 604.0
HFD2_k127_7518755_3 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 361.0
HFD2_k127_7518755_4 Peptidase C26 K07010 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005196 319.0
HFD2_k127_7518755_5 PFAM Phosphomethylpyrimidine kinase K00941,K14153,K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000002203 278.0
HFD2_k127_7518755_6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000001268 242.0
HFD2_k127_7518755_7 Late embryogenesis abundant protein - - - 0.00000000000000000000000000000000000000000000000000000000001294 216.0
HFD2_k127_7518755_8 PDZ DHR GLGF domain protein K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000007391 205.0
HFD2_k127_7518755_9 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000006209 181.0
HFD2_k127_7530631_0 Calcineurin-like phosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 501.0
HFD2_k127_7530631_1 PFAM Silent information regulator protein Sir2 K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000299 429.0
HFD2_k127_7530631_10 Biopolymer transport protein K03559 - - 0.00000000000000000000000000000000000000000000227 170.0
HFD2_k127_7530631_11 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000000000000000000000000000003742 158.0
HFD2_k127_7530631_12 Protein of unknown function (DUF423) - - - 0.000000000000000006619 94.0
HFD2_k127_7530631_2 Dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003487 320.0
HFD2_k127_7530631_3 PFAM MotA TolQ ExbB proton channel K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004862 312.0
HFD2_k127_7530631_4 Cys/Met metabolism PLP-dependent enzyme K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 312.0
HFD2_k127_7530631_5 TRAP transporter T-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002564 258.0
HFD2_k127_7530631_6 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000008196 246.0
HFD2_k127_7530631_7 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000000000000000000000000004621 237.0
HFD2_k127_7530631_8 ApaG domain K06195 - - 0.00000000000000000000000000000000000000000000000002335 186.0
HFD2_k127_7530631_9 N-terminal half of MaoC dehydratase - - - 0.00000000000000000000000000000000000000000000000009508 179.0
HFD2_k127_753443_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007963 571.0
HFD2_k127_753443_1 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002925 564.0
HFD2_k127_753443_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 421.0
HFD2_k127_753443_3 - K06198 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 345.0
HFD2_k127_753443_4 Formamidopyrimidine-DNA glycosylase N-terminal domain K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 355.0
HFD2_k127_753443_5 peroxiredoxin activity K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.0000000000000000000000000000000000000265 145.0
HFD2_k127_753443_6 PFAM AhpC TSA family K03564 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.11.1.15 0.000000000004423 69.0
HFD2_k127_7563649_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 577.0
HFD2_k127_7563649_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 394.0
HFD2_k127_7563649_2 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 372.0
HFD2_k127_7563649_3 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000000000002026 158.0
HFD2_k127_7605314_0 Elongation factor G, domain IV K02355 - - 0.0 1065.0
HFD2_k127_7605314_1 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 6.765e-254 795.0
HFD2_k127_7605314_10 Allophanate hydrolase subunit 1 K06351 - - 0.0000000000000000000000000000000000000000000000000000000005204 218.0
HFD2_k127_7605314_11 transcription regulator, contains HTH domain (MarR family) - - - 0.00000000000000000000000000000000000000000000000000004265 193.0
HFD2_k127_7605314_12 HNH nucleases - - - 0.0000000000000000000000000000000002824 135.0
HFD2_k127_7605314_13 GyrI-like small molecule binding domain K15770 - - 0.000000000000000000000004231 110.0
HFD2_k127_7605314_2 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002942 533.0
HFD2_k127_7605314_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 391.0
HFD2_k127_7605314_4 Belongs to the D-glutamate cyclase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 349.0
HFD2_k127_7605314_5 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 373.0
HFD2_k127_7605314_6 TIGRFAM urea amidolyase related protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 306.0
HFD2_k127_7605314_7 Belongs to the UPF0271 (lamB) family K07160 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 286.0
HFD2_k127_7605314_8 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001951 280.0
HFD2_k127_7605314_9 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000003915 239.0
HFD2_k127_7630630_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 9.56e-313 966.0
HFD2_k127_7630630_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005476 427.0
HFD2_k127_7630630_2 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000000000000000000000000000000000000000004572 234.0
HFD2_k127_7630630_4 Putative methyltransferase - - - 0.0000000000000000000000000000000000319 147.0
HFD2_k127_7630630_5 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000001521 123.0
HFD2_k127_7659153_0 UDP binding domain K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 568.0
HFD2_k127_7659153_2 - - - - 0.0003955 50.0
HFD2_k127_772534_0 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000701 456.0
HFD2_k127_772534_1 thiolester hydrolase activity - - - 0.0000000000000000000000000000000002001 151.0
HFD2_k127_772534_2 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.0000000000003817 69.0
HFD2_k127_772534_3 Protoglobin - - - 0.00002614 54.0
HFD2_k127_7869901_0 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 366.0
HFD2_k127_7869901_1 Pirin K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007456 344.0
HFD2_k127_7869901_2 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000376 332.0
HFD2_k127_7869901_3 GMP synthase (glutamine-hydrolyzing) activity K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000001047 209.0
HFD2_k127_7869901_6 - - - - 0.000000000000002684 87.0
HFD2_k127_7869901_7 Prolyl oligopeptidase family - - - 0.0000000000002364 70.0
HFD2_k127_7897614_0 Patatin-like phospholipase - - - 1.114e-203 644.0
HFD2_k127_7897614_1 Amino-transferase class IV K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 488.0
HFD2_k127_7897614_2 Amino acid permease - - - 0.000000009564 56.0
HFD2_k127_7915144_0 NUBPL iron-transfer P-loop NTPase K04562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006448 439.0
HFD2_k127_7915144_1 HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000002286 179.0
HFD2_k127_7915144_2 sequence-specific DNA binding - - - 0.00000000000000000000000000000000000000000000000004954 201.0
HFD2_k127_7930202_0 PFAM H transporting two-sector ATPase alpha beta subunit central region K02412,K03224 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 612.0
HFD2_k127_7930202_1 transglycosylase K08309 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009274,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006885 562.0
HFD2_k127_7930202_10 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives - - - 0.0000000000000000007872 89.0
HFD2_k127_7930202_11 flagellar assembly protein FliH K02411 - - 0.00001922 55.0
HFD2_k127_7930202_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002956 448.0
HFD2_k127_7930202_3 Cysteine-rich secretory protein family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008157 415.0
HFD2_k127_7930202_4 3'-5' exonuclease K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009185 382.0
HFD2_k127_7930202_5 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 351.0
HFD2_k127_7930202_6 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004005 319.0
HFD2_k127_7930202_7 Thioredoxin K03671 - - 0.0000000000000000000000000000000000000000000001175 193.0
HFD2_k127_7935334_0 helicase - - - 0.0 1179.0
HFD2_k127_7935334_1 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 1.509e-278 866.0
HFD2_k127_7935334_10 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000000002575 203.0
HFD2_k127_7935334_11 Crp-like helix-turn-helix domain K10914 - - 0.000000000000000000000000000000000000000000000000001631 203.0
HFD2_k127_7935334_12 Glyoxalase-like domain K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000000000001547 185.0
HFD2_k127_7935334_13 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.000000000000000000000000000000000000000000000003843 177.0
HFD2_k127_7935334_14 4Fe-4S dicluster domain K00125,K03646 - 1.17.1.9 0.0000000000000000000000000000000000000002214 172.0
HFD2_k127_7935334_15 PFAM DoxX family protein - - - 0.00000000000000000000000000000000000001424 158.0
HFD2_k127_7935334_16 Tautomerase enzyme - - - 0.00000000000000000000000000000000002879 145.0
HFD2_k127_7935334_17 - - - - 0.000000000000000000000000000001705 126.0
HFD2_k127_7935334_18 thiamine biosynthesis protein ThiS K03154 - - 0.0000000000000000000002129 113.0
HFD2_k127_7935334_19 PFAM Abortive infection protein K07052 - - 0.0000000000000000000003455 108.0
HFD2_k127_7935334_2 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 441.0
HFD2_k127_7935334_21 Domain of unknown function (DUF4350) - - - 0.0000000000000000009656 102.0
HFD2_k127_7935334_22 - - - - 0.000001279 61.0
HFD2_k127_7935334_3 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00112 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 423.0
HFD2_k127_7935334_4 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 391.0
HFD2_k127_7935334_6 associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 346.0
HFD2_k127_7935334_7 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 311.0
HFD2_k127_7935334_8 tRNA methyltransferase complex GCD14 subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001651 274.0
HFD2_k127_7935334_9 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000000002914 220.0
HFD2_k127_7959_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1065.0
HFD2_k127_7959_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 6.574e-285 884.0
HFD2_k127_7959_10 - - - - 0.000000000000000000000003468 112.0
HFD2_k127_7959_2 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008624 567.0
HFD2_k127_7959_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 404.0
HFD2_k127_7959_4 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 380.0
HFD2_k127_7959_5 RmlD substrate binding domain K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 312.0
HFD2_k127_7959_6 chemotaxis K03408 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003004 246.0
HFD2_k127_7959_7 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000000000000000000000000000001465 194.0
HFD2_k127_7959_8 transferase activity, transferring glycosyl groups K12994 - 2.4.1.349 0.0000000000000000000000000000000000000000001037 176.0
HFD2_k127_7959_9 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000008317 104.0
HFD2_k127_7959985_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1214.0
HFD2_k127_796385_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 2.939e-233 728.0
HFD2_k127_796385_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 5.195e-220 696.0
HFD2_k127_796385_2 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 395.0
HFD2_k127_796385_3 protein family UPF0079, ATPase K06925 - - 0.0000000000000000000000000000000000000000000000000459 200.0
HFD2_k127_796385_4 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000000000000005957 160.0
HFD2_k127_7968836_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0 1028.0
HFD2_k127_7968836_1 Participates in both transcription termination and antitermination K02600 - - 2.91e-306 956.0
HFD2_k127_7968836_11 Nucleic-acid-binding protein implicated in transcription termination K02600,K07742 - - 0.00000000000000000007866 91.0
HFD2_k127_7968836_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009233 606.0
HFD2_k127_7968836_3 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 423.0
HFD2_k127_7968836_4 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009598 382.0
HFD2_k127_7968836_5 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000044 357.0
HFD2_k127_7968836_6 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000000000000000000000000000000000002725 233.0
HFD2_k127_7968836_7 regulator K07773 - - 0.00000000000000000000000000000000000000000000000000000000000001288 233.0
HFD2_k127_7968836_8 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0000000000000000000000000000000009555 133.0
HFD2_k127_7968836_9 exodeoxyribonuclease VII activity K03602 - 3.1.11.6 0.00000000000000000000000001645 111.0
HFD2_k127_7987280_0 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 509.0
HFD2_k127_7987280_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004243 274.0
HFD2_k127_7987280_2 CRS1_YhbY K07574 - - 0.0000000000000000000000000000000006763 151.0
HFD2_k127_7992341_0 PFAM Major Facilitator Superfamily K08177 - - 3.594e-198 627.0
HFD2_k127_7992341_1 long-chain fatty acid transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005745 358.0
HFD2_k127_7992341_2 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000001688 213.0
HFD2_k127_7992341_4 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.00000000000000003649 82.0
HFD2_k127_8026772_0 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 1.532e-204 647.0
HFD2_k127_8026772_1 AIR carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 364.0
HFD2_k127_8026772_2 chemotaxis K03410 GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896,GO:0050918 - 0.0000000000000000000000000000000000000000000000000000000003332 226.0
HFD2_k127_8026772_3 Belongs to the LarC family K09121 - 4.99.1.12 0.0000003294 63.0
HFD2_k127_8039738_0 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 512.0
HFD2_k127_8039738_1 PBS lyase HEAT-like repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003216 486.0
HFD2_k127_8039738_2 HupE / UreJ protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007915 353.0
HFD2_k127_8039738_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001239 241.0
HFD2_k127_8046742_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 3.686e-302 955.0
HFD2_k127_8046742_1 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 501.0
HFD2_k127_8046742_11 - - - - 0.000000000000000000000000000000000000000000000000000000000003848 216.0
HFD2_k127_8046742_12 maF-like protein K06287 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0036218,GO:0036221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0047429 - 0.00000000000000000000000000000000000000000003671 181.0
HFD2_k127_8046742_2 peptidyl-prolyl isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 422.0
HFD2_k127_8046742_3 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006633 393.0
HFD2_k127_8046742_4 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 367.0
HFD2_k127_8046742_5 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000934 347.0
HFD2_k127_8046742_6 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 307.0
HFD2_k127_8046742_7 Protein of unknown function (DUF507) K09804 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002505 311.0
HFD2_k127_8046742_8 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001034 281.0
HFD2_k127_8070386_0 MMPL family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008492 446.0
HFD2_k127_8070386_1 Biotin-lipoyl like - - - 0.00000000000000000000000000000000000000000000000000000000003106 225.0
HFD2_k127_8070386_2 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.000000000000000000000000001837 118.0
HFD2_k127_8070536_0 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 432.0
HFD2_k127_8070536_1 Domain of unknown function (DUF4388) K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000003924 181.0
HFD2_k127_8092802_0 PFAM Phosphate acetyl butaryl transferase K00634 - 2.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 291.0
HFD2_k127_8092802_1 - - - - 0.0000000003645 69.0
HFD2_k127_8110492_0 HMGL-like K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 462.0
HFD2_k127_8110492_1 Carboxyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003563 433.0
HFD2_k127_8110492_2 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009033 351.0
HFD2_k127_8110492_3 methyltransferase activity K13613,K15677 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003583 311.0
HFD2_k127_8110492_4 B12 binding domain K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000000000798 240.0
HFD2_k127_8110492_5 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.00000000000002172 72.0
HFD2_k127_8117007_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 3.214e-315 989.0
HFD2_k127_8117007_1 Protein of unknown function (DUF1343) - - - 1.796e-198 630.0
HFD2_k127_8117007_2 PFAM Extracellular ligand-binding receptor K01999 - - 9.835e-198 625.0
HFD2_k127_8117007_3 Belongs to the binding-protein-dependent transport system permease family K01997,K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 461.0
HFD2_k127_8117007_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 362.0
HFD2_k127_8117007_5 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006072 308.0
HFD2_k127_8117007_6 arylsulfatase activity - - - 0.0000000000000000000000000000000000000000000000002458 187.0
HFD2_k127_8117007_7 Gram-negative porin - - - 0.000000000000000000000003636 117.0
HFD2_k127_8164341_0 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000003832 216.0
HFD2_k127_8164341_1 transcriptional regulator - - - 0.0000000000000000000000000000000000000000824 158.0
HFD2_k127_8164341_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000009473 146.0
HFD2_k127_8164341_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000001962 75.0
HFD2_k127_8164341_4 RDD family - - - 0.000007089 57.0
HFD2_k127_8204952_0 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008328 597.0
HFD2_k127_8204952_1 lipopolysaccharide transport K04744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007709 598.0
HFD2_k127_8204952_10 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 326.0
HFD2_k127_8204952_11 translation initiation factor activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 308.0
HFD2_k127_8204952_12 Bacterial regulatory proteins, tetR family K13770 - - 0.000000000000000000000000000000000000000000000000000000000000000003777 258.0
HFD2_k127_8204952_13 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000000000218 118.0
HFD2_k127_8204952_14 PFAM E1-E2 ATPase-associated domain protein, Haloacid dehalogenase domain protein hydrolase, cation transporting ATPase domain protein K01531 - 3.6.3.2 0.00005724 46.0
HFD2_k127_8204952_2 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 544.0
HFD2_k127_8204952_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 506.0
HFD2_k127_8204952_4 COG1233 Phytoene dehydrogenase and related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 502.0
HFD2_k127_8204952_5 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 477.0
HFD2_k127_8204952_6 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 457.0
HFD2_k127_8204952_7 TIGRFAM amidohydrolase K12941 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 364.0
HFD2_k127_8204952_8 cAMP phosphodiesterases class-II K01120 - 3.1.4.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 333.0
HFD2_k127_8204952_9 cyclic nucleotide-binding K10914 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 302.0
HFD2_k127_8227565_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 4.394e-230 730.0
HFD2_k127_8227565_1 Belongs to the N(4) N(6)-methyltransferase family K00571 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 488.0
HFD2_k127_8227565_11 PFAM thioesterase superfamily K02614 - - 0.000000000000000000000000000000000000000000000000000004069 200.0
HFD2_k127_8227565_12 Phosphoribosyl transferase domain K07100 - - 0.00000000000000000000000000000000000001388 153.0
HFD2_k127_8227565_13 Redoxin K03564 - 1.11.1.15 0.0000000000000000000000000000000001775 134.0
HFD2_k127_8227565_14 Redoxin K03564 - 1.11.1.15 0.0000000000000000000001714 97.0
HFD2_k127_8227565_16 GDP-mannose mannosyl hydrolase activity K01515,K03574 - 3.6.1.13,3.6.1.55 0.00000000000000179 76.0
HFD2_k127_8227565_2 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004875 513.0
HFD2_k127_8227565_3 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005308 469.0
HFD2_k127_8227565_4 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 400.0
HFD2_k127_8227565_5 Belongs to the GcvT family K06980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 389.0
HFD2_k127_8227565_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 384.0
HFD2_k127_8227565_7 CarD-like/TRCF domain K07736 GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0040007,GO:0042594,GO:0044419,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001862 303.0
HFD2_k127_8227565_8 metallopeptidase activity K06974 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000462 273.0
HFD2_k127_8231439_0 Domain of Unknown Function (DUF748) - - - 1.616e-220 721.0
HFD2_k127_8231439_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004797 443.0
HFD2_k127_8231439_2 tRNA synthetases class I (W and Y) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007475 365.0
HFD2_k127_8231439_4 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 295.0
HFD2_k127_8231439_5 heat shock protein binding - - - 0.0000000000000000000000000001798 117.0
HFD2_k127_8231439_6 heat shock protein binding - - - 0.0000000000000000000000000146 126.0
HFD2_k127_8234123_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 1.176e-319 1024.0
HFD2_k127_8234123_1 Large family of predicted nucleotide-binding domains K07175 - - 3.69e-243 756.0
HFD2_k127_8234123_10 PFAM iron dependent repressor K03709 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 340.0
HFD2_k127_8234123_11 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000000000000000000000003373 224.0
HFD2_k127_8234123_12 FMN_bind - - - 0.000000000000000000000000000000000000000000000000000149 207.0
HFD2_k127_8234123_14 - - - - 0.0000000000000000000000000000000000000005105 162.0
HFD2_k127_8234123_15 Belongs to the UPF0250 family K09158 - - 0.0000000000000000000000000000003826 124.0
HFD2_k127_8234123_17 Cupin - - - 0.000000000000000000000000002946 128.0
HFD2_k127_8234123_18 Regulatory protein, FmdB family - - - 0.0000000000000000000000001692 109.0
HFD2_k127_8234123_19 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589,K13052 - - 0.000000003186 63.0
HFD2_k127_8234123_2 diguanylate cyclase - - - 2.669e-241 772.0
HFD2_k127_8234123_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005627 489.0
HFD2_k127_8234123_4 Pfam Transposase IS66 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007908 478.0
HFD2_k127_8234123_5 Diacylglycerol kinase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000885 446.0
HFD2_k127_8234123_6 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009576 419.0
HFD2_k127_8234123_7 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004254 377.0
HFD2_k127_8234123_8 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009627 381.0
HFD2_k127_8234123_9 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC K06148,K16012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009311 345.0
HFD2_k127_8284548_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015,K15893 - 1.1.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005524 352.0
HFD2_k127_8284548_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 312.0
HFD2_k127_8284548_2 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.000000000000000000000000000000000000000000005107 180.0
HFD2_k127_8284548_3 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000000000001095 92.0
HFD2_k127_8291042_0 two component, sigma54 specific, transcriptional regulator, Fis family K07713 - - 1.488e-205 671.0
HFD2_k127_8291042_1 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 455.0
HFD2_k127_8291042_10 - - - - 0.000000000000000000000000000000000000000000000189 180.0
HFD2_k127_8291042_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003595 482.0
HFD2_k127_8291042_3 PFAM ATP-binding region, ATPase domain protein K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004787 449.0
HFD2_k127_8291042_4 PFAM ABC transporter K01990,K01992,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 427.0
HFD2_k127_8291042_5 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 395.0
HFD2_k127_8291042_6 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 350.0
HFD2_k127_8291042_7 PFAM secretion protein HlyD family protein K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000477 339.0
HFD2_k127_8291042_8 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000014 276.0
HFD2_k127_8291042_9 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000005677 231.0
HFD2_k127_8322335_0 metallopeptidase activity K01179 - 3.2.1.4 0.0 1073.0
HFD2_k127_8322335_1 Bacterial protein of unknown function (DUF853) K06915 - - 3.466e-204 648.0
HFD2_k127_8322335_10 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003576 325.0
HFD2_k127_8322335_11 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000161 273.0
HFD2_k127_8322335_12 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.00000000000000000000000000000000000000000000000001543 188.0
HFD2_k127_8322335_13 - - - - 0.00000000000000000000000000000000000000000000003983 189.0
HFD2_k127_8322335_14 - - - - 0.000000000000000000000000000000008329 144.0
HFD2_k127_8322335_15 - - - - 0.00000000000000000000000000000003344 134.0
HFD2_k127_8322335_16 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000004507 143.0
HFD2_k127_8322335_17 - - - - 0.000000000000000000000000004632 117.0
HFD2_k127_8322335_18 - - - - 0.0000000000000000000003207 104.0
HFD2_k127_8322335_19 Transcriptional regulator K13643 - - 0.000000000000000000001543 100.0
HFD2_k127_8322335_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 1.593e-198 627.0
HFD2_k127_8322335_20 Uncharacterised protein family UPF0066 - - - 0.000000000000000000005538 105.0
HFD2_k127_8322335_21 YMGG-like Gly-zipper - - - 0.0000000000000000001607 101.0
HFD2_k127_8322335_22 - - - - 0.0000000000000007014 91.0
HFD2_k127_8322335_23 - - - - 0.000000000002257 75.0
HFD2_k127_8322335_25 Hemerythrin HHE cation binding domain - - - 0.0000001161 64.0
HFD2_k127_8322335_26 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.00004798 56.0
HFD2_k127_8322335_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005701 551.0
HFD2_k127_8322335_4 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 526.0
HFD2_k127_8322335_5 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005121 515.0
HFD2_k127_8322335_6 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 467.0
HFD2_k127_8322335_7 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 392.0
HFD2_k127_8322335_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006667 341.0
HFD2_k127_8322335_9 esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004382 331.0
HFD2_k127_8345178_0 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 6.262e-304 951.0
HFD2_k127_8345178_1 Alpha-amylase domain K01176 - 3.2.1.1 1.614e-256 799.0
HFD2_k127_8345178_10 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005956 309.0
HFD2_k127_8345178_11 PFAM Hemerythrin HHE cation binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000003039 249.0
HFD2_k127_8345178_12 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000000000000005847 201.0
HFD2_k127_8345178_13 CBS domain K04767,K07168,K07182 - - 0.00000000000000000000000000000000000000000000000000656 195.0
HFD2_k127_8345178_14 TIGRFAM Molybdopterin-guanine dinucleotide biosynthesis protein B K03753 - - 0.0000000000000000000000000000000000000000000001318 190.0
HFD2_k127_8345178_15 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000009434 190.0
HFD2_k127_8345178_16 Psort location Cytoplasmic, score K01759,K03827 - 4.4.1.5 0.00000000000000000000000000006582 135.0
HFD2_k127_8345178_17 mttA/Hcf106 family K03116 - - 0.0000000000001209 74.0
HFD2_k127_8345178_18 DnaK suppressor protein - - - 0.0000000000004385 82.0
HFD2_k127_8345178_2 Sigma-54 interaction domain - - - 5.757e-241 764.0
HFD2_k127_8345178_3 Protoglobin - GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005515,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0019825,GO:0020037,GO:0023014,GO:0023052,GO:0035556,GO:0036094,GO:0036211,GO:0042802,GO:0042803,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046906,GO:0046983,GO:0048037,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0097159,GO:0140096,GO:1901363,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008367 494.0
HFD2_k127_8345178_4 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008499 505.0
HFD2_k127_8345178_5 Belongs to the glycosyl hydrolase 13 family K01200 - 3.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 495.0
HFD2_k127_8345178_6 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004433 478.0
HFD2_k127_8345178_7 Crp-like helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 386.0
HFD2_k127_8345178_9 Phospholipase D Active site motif K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000409 349.0
HFD2_k127_8392758_0 Putative glutamine amidotransferase - - - 0.0 1037.0
HFD2_k127_8392758_1 DbpA RNA binding domain K03732,K05592 - 3.6.4.13 1.425e-269 843.0
HFD2_k127_8392758_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 475.0
HFD2_k127_8392758_3 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 435.0
HFD2_k127_8392758_4 Chromate transporter K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 424.0
HFD2_k127_8392758_5 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 395.0
HFD2_k127_8392758_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000005297 233.0
HFD2_k127_8392758_7 oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000005066 220.0
HFD2_k127_8392758_9 - - - - 0.00001482 58.0
HFD2_k127_8405291_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 2.542e-263 821.0
HFD2_k127_8405291_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003972 417.0
HFD2_k127_8405291_2 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 285.0
HFD2_k127_8405291_3 iron ion homeostasis K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002328 282.0
HFD2_k127_8405291_4 GGDEF domain K21009 - - 0.0000000000000000000000000000000000000000000000000000000000000001964 231.0
HFD2_k127_8405291_5 response regulator K03654 - 3.6.4.12 0.000000000000000000000000000000000000000000000007403 177.0
HFD2_k127_8425560_0 Elongator protein 3, MiaB family, Radical SAM - - - 7.726e-305 942.0
HFD2_k127_8425560_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 1.158e-213 679.0
HFD2_k127_8425560_10 Protein of unknown function (DUF1460) - - - 0.000000000000000000000000000000000000000000000000005791 194.0
HFD2_k127_8425560_11 cheY-homologous receiver domain K07657 - - 0.00000000000000000000002731 101.0
HFD2_k127_8425560_2 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005215 509.0
HFD2_k127_8425560_3 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002953 491.0
HFD2_k127_8425560_4 Belongs to the ompA family K03286 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006918 409.0
HFD2_k127_8425560_5 ADP-ribosylation factor family K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007245 381.0
HFD2_k127_8425560_6 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 350.0
HFD2_k127_8425560_7 Roadblock/LC7 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005429 296.0
HFD2_k127_8425560_8 COG1651 Protein-disulfide isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 300.0
HFD2_k127_8425560_9 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.00000000000000000000000000000000000000000000000000000000002962 231.0
HFD2_k127_8482456_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0 1109.0
HFD2_k127_8482456_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 7.933e-291 912.0
HFD2_k127_8482456_10 cheY-homologous receiver domain - - - 0.00000000000000000006549 97.0
HFD2_k127_8482456_11 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000001407 104.0
HFD2_k127_8482456_2 Peptidase family S58 K01266 - 3.4.11.19 1.943e-209 667.0
HFD2_k127_8482456_3 Elongator protein 3, MiaB family, Radical SAM - - - 6.37e-196 622.0
HFD2_k127_8482456_4 ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 611.0
HFD2_k127_8482456_5 MoeA C-terminal region (domain IV) K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007216 499.0
HFD2_k127_8482456_6 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 305.0
HFD2_k127_8482456_7 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001535 248.0
HFD2_k127_8482456_8 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.0000000000000000000000000000000000000000000000124 177.0
HFD2_k127_8482456_9 sequence-specific DNA binding - - - 0.0000000000000000000000000001001 115.0
HFD2_k127_8516744_0 uridine kinase K00876 - 2.7.1.48 1.409e-291 923.0
HFD2_k127_8516744_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008428 616.0
HFD2_k127_8516744_10 - - - - 0.0000000000000000000000000000000000000000933 164.0
HFD2_k127_8516744_13 - - - - 0.000000000000000001038 88.0
HFD2_k127_8516744_14 nitric oxide reductase K04561 - 1.7.2.5 0.00005266 55.0
HFD2_k127_8516744_2 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006318 535.0
HFD2_k127_8516744_3 tRNA synthetases class II (D, K and N) K04568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003803 458.0
HFD2_k127_8516744_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 460.0
HFD2_k127_8516744_5 Oligoendopeptidase f - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 325.0
HFD2_k127_8516744_6 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001069 250.0
HFD2_k127_8516744_7 PAS sensor protein - - - 0.000000000000000000000000000000000000000000000000009451 183.0
HFD2_k127_8516744_8 1,4-alpha-glucan branching enzyme activity K00700 - 2.4.1.18 0.0000000000000000000000000000000000000000000000001581 192.0
HFD2_k127_8604837_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 4.396e-197 628.0
HFD2_k127_8604837_1 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.00000000000000000000000000000000009567 136.0
HFD2_k127_8604837_2 Belongs to the CarA family K01956 - 6.3.5.5 0.0000000000000000000000005407 120.0
HFD2_k127_8632261_0 Type IV pilus assembly protein PilM; K02461 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 368.0
HFD2_k127_8632261_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009308 246.0
HFD2_k127_8632261_2 Type II secretion system (T2SS), protein M K02462 - - 0.00000000000000000000000000000000000000000000000000001483 205.0
HFD2_k127_8632261_3 PFAM chemotaxis sensory transducer - - - 0.00000000000000000000003736 102.0
HFD2_k127_8636895_0 Heat shock 70 kDa protein K04043 - - 0.0 1060.0
HFD2_k127_8636895_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 3.244e-263 825.0
HFD2_k127_8636895_2 ABC-type branched-chain amino acid transport K07121 - - 5.811e-224 713.0
HFD2_k127_8636895_3 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000042 519.0
HFD2_k127_8636895_4 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 486.0
HFD2_k127_8636895_5 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 382.0
HFD2_k127_8636895_6 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000007274 254.0
HFD2_k127_8636895_7 photosynthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000001203 257.0
HFD2_k127_88079_0 General secretory system II, protein E domain protein K02454 - - 0.0 1027.0
HFD2_k127_88079_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 2.246e-316 982.0
HFD2_k127_88079_2 ATPase family associated with various cellular activities (AAA) - - - 1.083e-222 700.0
HFD2_k127_88079_3 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004238 474.0
HFD2_k127_88079_4 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008187 444.0
HFD2_k127_88079_5 Inositol monophosphatase family - - - 0.00000000000000000000000000000000000000000000000000000003117 199.0
HFD2_k127_88079_6 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000002571 144.0
HFD2_k127_88079_7 Regulatory protein, FmdB family - - - 0.00000000000002082 88.0
HFD2_k127_885354_0 AAA ATPase domain - - - 1.339e-318 1020.0
HFD2_k127_885354_1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 626.0
HFD2_k127_885354_10 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004275 271.0
HFD2_k127_885354_11 dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000001477 250.0
HFD2_k127_885354_12 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000002337 235.0
HFD2_k127_885354_13 Enoyl-CoA hydratase/isomerase K07536 - - 0.000000000000000000000000000000000000000000000000000102 194.0
HFD2_k127_885354_14 COG0517, FOG CBS domain - - - 0.0000000000000000000000000000000000000001207 160.0
HFD2_k127_885354_15 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.000000000000000000000000000000000316 136.0
HFD2_k127_885354_18 Cupin 2, conserved barrel domain protein K18991 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009438,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019172,GO:0019243,GO:0019249,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046185,GO:0046394,GO:0051596,GO:0061727,GO:0071704,GO:0072330,GO:1901575,GO:1901576,GO:1901615,GO:1901617 - 0.000000000000000000000000003216 127.0
HFD2_k127_885354_19 Protein of unknown function (DUF4242) - - - 0.000000000000000000000000005843 112.0
HFD2_k127_885354_2 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 438.0
HFD2_k127_885354_20 PFAM ATP phosphoribosyltransferase - - - 0.000000000000000000000005802 114.0
HFD2_k127_885354_21 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000002771 104.0
HFD2_k127_885354_3 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01781 - 5.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005493 391.0
HFD2_k127_885354_4 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008575 400.0
HFD2_k127_885354_5 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004095 367.0
HFD2_k127_885354_6 3-oxo-5-alpha-steroid 4-dehydrogenase K12343 - 1.3.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 316.0
HFD2_k127_885354_7 GLTT repeat (6 copies) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 303.0
HFD2_k127_885354_8 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000476 295.0
HFD2_k127_885354_9 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008928 302.0
HFD2_k127_910651_0 Sodium/hydrogen exchanger family K11105 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007878 549.0
HFD2_k127_910651_1 Domain of unknown function (DUF4010) - - - 0.0000000000000000000000000000000000000000000000000000000000000002193 236.0
HFD2_k127_910651_2 PFAM Ammonium Transporter Family K03320 - - 0.0000000000000134 76.0
HFD2_k127_944137_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 591.0
HFD2_k127_944137_1 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 541.0
HFD2_k127_944137_2 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 340.0
HFD2_k127_944137_3 Serine Threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009354 362.0
HFD2_k127_944137_4 Imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 316.0
HFD2_k127_944137_5 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000448 296.0
HFD2_k127_944137_6 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003859 313.0
HFD2_k127_944137_7 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000007488 268.0
HFD2_k127_950770_0 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 492.0
HFD2_k127_950770_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000004038 260.0
HFD2_k127_950770_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000009097 228.0
HFD2_k127_950770_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000007067 190.0
HFD2_k127_950770_4 Heavy-metal resistance - - - 0.000005504 54.0
HFD2_k127_992949_0 DnaJ C terminal domain K03686,K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000377 466.0
HFD2_k127_992949_1 lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008334 330.0
HFD2_k127_993672_0 Chromate transporter K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 439.0
HFD2_k127_993672_1 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000726 355.0
HFD2_k127_993672_2 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 362.0
HFD2_k127_993672_3 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008889 324.0
HFD2_k127_993672_4 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000003882 164.0
HFD2_k127_993672_5 Branched-chain amino acid transport system / permease component K02057,K10440 - - 0.0002881 46.0