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Overview

ID MAG01657
Name HFD2_bin.49
Sample SMP0044
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Polarisedimenticolia
Order JACPZX01
Family DASXTC01
Genus DATEEA01
Species
Assembly information
Completeness (%) 84.85
Contamination (%) 0.67
GC content (%) 70.0
N50 (bp) 11,507
Genome size (bp) 2,987,279

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2481

Gene name Description KEGG GOs EC E-value Score Sequence
HFD2_k127_1040421_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.312e-255 803.0
HFD2_k127_1040421_1 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.000000000000000000000000000000000000000000000000000000000000000002826 241.0
HFD2_k127_1040421_2 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000007966 248.0
HFD2_k127_1040421_3 PFAM YbbR family protein - - - 0.000000000000000000415 93.0
HFD2_k127_1040421_4 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000005312 83.0
HFD2_k127_1059135_0 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 446.0
HFD2_k127_1059135_1 guanosine tetraphosphate metabolic process K07816 - 2.7.6.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 360.0
HFD2_k127_1059135_2 Histidine kinase K02482,K03557 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000001207 227.0
HFD2_k127_1059135_3 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000000000000006746 221.0
HFD2_k127_1059135_4 SCO1/SenC K07152 - - 0.000000000000000000000000000000001337 150.0
HFD2_k127_1059135_5 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000001328 135.0
HFD2_k127_1059135_6 nitric oxide dioxygenase activity - - - 0.0000000000000000000000001346 111.0
HFD2_k127_1059135_7 - - - - 0.00000000000000000605 96.0
HFD2_k127_1059135_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000918 85.0
HFD2_k127_1059135_9 - - - - 0.00000000000000122 89.0
HFD2_k127_1103441_0 Belongs to the ABC transporter superfamily K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 402.0
HFD2_k127_1103441_1 Belongs to the ABC transporter superfamily K02031,K12371,K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 364.0
HFD2_k127_1118424_0 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 321.0
HFD2_k127_1118424_1 MacB-like periplasmic core domain K02004,K05685 - - 0.000000000000000000000000000000000000000000000000000000000000001083 224.0
HFD2_k127_1120832_0 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 563.0
HFD2_k127_1120832_1 Pyridoxal-phosphate dependent enzyme K01697,K01738 - 2.5.1.47,4.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001264 281.0
HFD2_k127_1126254_0 histidine kinase A domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 401.0
HFD2_k127_1126254_1 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000002111 208.0
HFD2_k127_1126254_2 Helix-turn-helix domain - - - 0.000000000000000000000000000000000001676 145.0
HFD2_k127_1126254_3 Methanol dehydrogenase K06872 - - 0.0000000000000000000000000000000001161 141.0
HFD2_k127_1126254_4 nucleotidyltransferase activity - - - 0.00000000000000000000000000001063 130.0
HFD2_k127_1126254_5 YtxH-like protein - - - 0.000351 51.0
HFD2_k127_1149751_0 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 3.3e-199 646.0
HFD2_k127_1149751_1 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007191 404.0
HFD2_k127_1149751_2 Hydantoinase/oxoprolinase K01473 - 3.5.2.14 0.000000000000000000000000000000000000000004122 164.0
HFD2_k127_1149751_3 Acetyltransferase (GNAT) domain K14682 - 2.3.1.1 0.0000000000000000000000000000000000001776 145.0
HFD2_k127_1149751_4 cytochrome C peroxidase - - - 0.0000001206 59.0
HFD2_k127_115520_0 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 377.0
HFD2_k127_115520_1 Phenazine biosynthesis-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001565 273.0
HFD2_k127_115520_2 Protein kinase domain K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000002457 228.0
HFD2_k127_115520_3 Histidine kinase-like ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000002018 201.0
HFD2_k127_115520_4 Transcriptional regulator K07734 - - 0.000000000000000000000000000000000000000000002619 171.0
HFD2_k127_115520_5 - - - - 0.000000000000000000000000000005096 127.0
HFD2_k127_1164301_0 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 319.0
HFD2_k127_1164301_1 YceG-like family K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000001533 254.0
HFD2_k127_1164301_10 nucleotide catabolic process - - - 0.000000000002177 68.0
HFD2_k127_1164301_11 Protein of unknown function (DUF721) - - - 0.0001427 51.0
HFD2_k127_1164301_12 cellulose synthase operon C domain protein K20543 - - 0.0001804 54.0
HFD2_k127_1164301_2 ABC-type uncharacterized transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000002579 240.0
HFD2_k127_1164301_3 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000001471 200.0
HFD2_k127_1164301_4 Zn peptidase - - - 0.0000000000000000000000000000000000000000000005251 186.0
HFD2_k127_1164301_5 spermidine synthase activity K00797 GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.00000000000000000000000000000000000000002957 172.0
HFD2_k127_1164301_6 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000007623 155.0
HFD2_k127_1164301_7 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00000000000000000000000000000000004456 143.0
HFD2_k127_1164301_8 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - - 0.000000000000000002933 98.0
HFD2_k127_1164301_9 Domain of unknown function (DUF4340) - - - 0.00000000000000009393 94.0
HFD2_k127_119211_0 Glycosyl transferase family group 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 499.0
HFD2_k127_119211_1 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000006824 196.0
HFD2_k127_119211_2 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000000000000007998 188.0
HFD2_k127_119211_3 deoxyhypusine monooxygenase activity - - - 0.00000000000000000000000000000000000000277 162.0
HFD2_k127_119211_4 Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation K07130 GO:0003674,GO:0003824,GO:0004061,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.9 0.000000000000000000000000000000000001973 147.0
HFD2_k127_119211_5 diguanylate cyclase - - - 0.000000000000000000000000000186 119.0
HFD2_k127_119211_6 Uncharacterized protein conserved in bacteria (DUF2059) K09924 - - 0.0000000007057 66.0
HFD2_k127_1195000_0 Protein of unknown function (DUF1428) - - - 0.0000000000000000000000000000000000000000000000000001343 188.0
HFD2_k127_1195000_1 Appr-1'-p processing enzyme - - - 0.0000000000000000000000000000000000000005587 151.0
HFD2_k127_1195000_2 PFAM TspO MBR family K05770 - - 0.00000000000000000000000000000000000004177 149.0
HFD2_k127_1195000_3 BrnA antitoxin of type II toxin-antitoxin system - - - 0.000000000000000000000000001113 117.0
HFD2_k127_1195000_4 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.00000002594 57.0
HFD2_k127_1214216_0 Insulinase (Peptidase family M16) K07263 - - 4.285e-300 954.0
HFD2_k127_1214216_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000005717 179.0
HFD2_k127_1214216_2 - - - - 0.00000000000000000003642 102.0
HFD2_k127_1216028_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002523 493.0
HFD2_k127_1216028_1 Glyceraldehyde-3-phosphate dehydrogenase K00150 - 1.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008981 448.0
HFD2_k127_1216028_10 - - - - 0.00000000000000000000538 94.0
HFD2_k127_1216028_11 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.00000000000000000005422 98.0
HFD2_k127_1216028_12 Belongs to the BolA IbaG family K05527 - - 0.00000000000000000005493 93.0
HFD2_k127_1216028_13 PTS HPr component phosphorylation site K11189 - - 0.00000000000000006638 94.0
HFD2_k127_1216028_14 PFAM acylphosphatase K01512 - 3.6.1.7 0.000000000000000734 82.0
HFD2_k127_1216028_16 hydrolase K01048 - 3.1.1.5 0.00003487 52.0
HFD2_k127_1216028_2 FAD dependent oxidoreductase K15736 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 439.0
HFD2_k127_1216028_3 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 335.0
HFD2_k127_1216028_4 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 297.0
HFD2_k127_1216028_5 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000956 254.0
HFD2_k127_1216028_6 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0030091,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000375 253.0
HFD2_k127_1216028_7 Mannose-6-phosphate isomerase - - - 0.000000000000000000000000000000000000000001324 160.0
HFD2_k127_1216028_8 Phosphotransferase system mannose fructose-specific component IIA K02793 - 2.7.1.191 0.00000000000000000000000001165 114.0
HFD2_k127_1216028_9 Regulatory protein - - - 0.000000000000000000000001378 109.0
HFD2_k127_1234107_0 Trypsin K04771,K04772 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009811 356.0
HFD2_k127_1234107_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000049,GO:0000154,GO:0001510,GO:0002935,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016426,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070040,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:0140102,GO:1901360,GO:1901363 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 328.0
HFD2_k127_1234107_2 Phosphomethylpyrimidine kinase K00941,K03147,K21219 GO:0008150,GO:0040007 2.5.1.3,2.7.1.49,2.7.4.7,4.1.99.17 0.0000000000000000000000000000000000000000000000000000000000000000004937 248.0
HFD2_k127_1234107_3 serine-type endopeptidase activity K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000001261 209.0
HFD2_k127_1234107_4 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.0000000000000000000000000000000000000000000000001393 187.0
HFD2_k127_1234107_5 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000002387 148.0
HFD2_k127_1234107_6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.000000000000000000000000000008441 137.0
HFD2_k127_1234107_7 Binding-protein-dependent transport system inner membrane component K02033,K15585 - - 0.000000000000003944 76.0
HFD2_k127_1260903_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000003112 243.0
HFD2_k127_1260903_1 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007292 258.0
HFD2_k127_1260903_2 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.00000000000000000000000000000000000000000000000000000000000000006333 241.0
HFD2_k127_1260903_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000005406 220.0
HFD2_k127_1260903_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000005114 199.0
HFD2_k127_1260903_5 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752,K13818 - 2.7.7.77 0.000000000000000000006081 105.0
HFD2_k127_1260903_6 Rieske-like [2Fe-2S] domain K05710 - - 0.000000000000001451 88.0
HFD2_k127_1260903_7 Putative regulatory protein - - - 0.000005224 55.0
HFD2_k127_1316668_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 4.92e-223 706.0
HFD2_k127_1316668_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000005416 207.0
HFD2_k127_1316668_2 Pkd domain containing protein - - - 0.00000000000000000000000000000000000000000000000000005609 214.0
HFD2_k127_1316668_3 Type II/IV secretion system protein K02669 - - 0.000000000002079 72.0
HFD2_k127_1378055_0 photoreceptor activity K03412,K03413,K13924 - 2.1.1.80,3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000002981 153.0
HFD2_k127_1378055_1 phosphorelay signal transduction system - - - 0.00000000000000000000001207 113.0
HFD2_k127_1378055_2 Response regulator receiver domain - - - 0.000000000124 73.0
HFD2_k127_1395075_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 519.0
HFD2_k127_1395075_1 ABC transporter K01990 - - 0.0000000000000000000000000000000000003793 148.0
HFD2_k127_1395075_2 Molybdopterin oxidoreductase K00123 - 1.17.1.9 0.00000000000000000000000000001565 121.0
HFD2_k127_1395075_3 Transcriptional K07979 - - 0.000000000000000000007822 96.0
HFD2_k127_1413664_0 ferrous iron transmembrane transporter activity K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007827 602.0
HFD2_k127_1413664_1 Domains REC, sigma54 interaction, HTH8 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006818 510.0
HFD2_k127_1413664_10 guanyl-nucleotide exchange factor activity K02034 - - 0.00000000000000000000000000000000000003053 166.0
HFD2_k127_1413664_11 - K01992,K19341 - - 0.000000000000000000000000000000006715 138.0
HFD2_k127_1413664_12 ATPase activity K01990,K19340 - - 0.00000000000000000000000000000001074 148.0
HFD2_k127_1413664_13 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000003986 123.0
HFD2_k127_1413664_14 BON domain - - - 0.00000000000000000001428 98.0
HFD2_k127_1413664_15 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000007033 68.0
HFD2_k127_1413664_2 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 399.0
HFD2_k127_1413664_3 membrane organization K07277,K09800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004397 422.0
HFD2_k127_1413664_4 Peptidase M16 K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009805 361.0
HFD2_k127_1413664_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002914 333.0
HFD2_k127_1413664_6 PFAM iron dependent repressor K03709 - - 0.000000000000000000000000000000000000000000000000000000000006725 218.0
HFD2_k127_1413664_7 ATPase activity K01990,K19340 - - 0.0000000000000000000000000000000000000000000000000000002063 198.0
HFD2_k127_1413664_8 aminopeptidase - - - 0.00000000000000000000000000000000000001653 166.0
HFD2_k127_1413664_9 Periplasmic copper-binding protein (NosD) - - - 0.00000000000000000000000000000000000003053 166.0
HFD2_k127_1413707_0 Endoribonuclease that initiates mRNA decay K18682 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004434 378.0
HFD2_k127_1413707_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601,K03797 - 3.1.11.6,3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000578 342.0
HFD2_k127_1413707_2 YmdB-like protein K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 303.0
HFD2_k127_1438430_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 415.0
HFD2_k127_1438430_1 TIGRFAM efflux transporter, RND family, MFP subunit K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000002138 248.0
HFD2_k127_1438430_2 Putative MetA-pathway of phenol degradation - - - 0.00000000000000000000009663 109.0
HFD2_k127_1438430_3 Phospholipid methyltransferase - - - 0.000000000000166 79.0
HFD2_k127_1438430_4 - - - - 0.0000000000005057 76.0
HFD2_k127_1438430_5 cold-shock protein K03704 - - 0.000000000005994 69.0
HFD2_k127_1438430_6 Intracellular proteinase inhibitor - - - 0.0000005236 62.0
HFD2_k127_1438430_8 site-specific DNA-methyltransferase (adenine-specific) activity K03427 - 2.1.1.72 0.0001077 51.0
HFD2_k127_1457411_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003121 593.0
HFD2_k127_1457411_1 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.0005702 51.0
HFD2_k127_1468628_0 cystathionine gamma-synthase activity K01739,K01740,K01760,K01761 - 2.5.1.48,2.5.1.49,4.4.1.11,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000009724 261.0
HFD2_k127_1468628_1 Proline dehydrogenase K00318 - - 0.000000000000000000000000000000000000000000000000000000000000000000001709 254.0
HFD2_k127_1468628_2 FemAB family - - - 0.0000000000000000000000000000002323 141.0
HFD2_k127_1468628_3 Protein involved in cellulose biosynthesis - - - 0.000000000000000001717 100.0
HFD2_k127_1468628_4 PFAM formyl transferase domain protein - - - 0.00000000000000004171 91.0
HFD2_k127_1468628_5 Transcriptional regulatory protein, C terminal - - - 0.0000000000008443 80.0
HFD2_k127_1468628_6 amelogenesis K07999 GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0004252,GO:0005488,GO:0005575,GO:0005576,GO:0005615,GO:0006508,GO:0006807,GO:0007275,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0009653,GO:0009887,GO:0009987,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022411,GO:0022603,GO:0022617,GO:0030163,GO:0030198,GO:0030574,GO:0032501,GO:0032502,GO:0032963,GO:0042475,GO:0042476,GO:0042481,GO:0042487,GO:0043062,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044421,GO:0046872,GO:0046914,GO:0048513,GO:0048646,GO:0048731,GO:0048856,GO:0050789,GO:0050793,GO:0051239,GO:0065007,GO:0070011,GO:0070167,GO:0070170,GO:0070173,GO:0071704,GO:0071840,GO:0097186,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:2000026,GO:2000027 - 0.0002927 53.0
HFD2_k127_1535794_0 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006768 595.0
HFD2_k127_1535794_1 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004746 406.0
HFD2_k127_1535794_10 ATP synthesis coupled proton transport K02109 - - 0.000000000000000000000000022 114.0
HFD2_k127_1535794_11 TIGRFAM phosphodiesterase, MJ0936 - - - 0.0000000000000000000001375 106.0
HFD2_k127_1535794_12 PFAM PEGA domain - - - 0.0000000000007422 82.0
HFD2_k127_1535794_13 ATP hydrolysis coupled proton transport K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000264 75.0
HFD2_k127_1535794_14 TonB dependent receptor - - - 0.00008035 51.0
HFD2_k127_1535794_15 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.0001053 55.0
HFD2_k127_1535794_16 40-residue YVTN family beta-propeller repeat - - - 0.0004654 53.0
HFD2_k127_1535794_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 400.0
HFD2_k127_1535794_3 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002383 286.0
HFD2_k127_1535794_4 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001471 283.0
HFD2_k127_1535794_5 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000002017 280.0
HFD2_k127_1535794_6 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000001119 220.0
HFD2_k127_1535794_7 COG3119 Arylsulfatase A and related enzymes K01130 - 3.1.6.1 0.000000000000000000000000000000000000000000001469 186.0
HFD2_k127_1535794_8 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000000000004582 166.0
HFD2_k127_1535794_9 Helix-turn-helix domain - - - 0.0000000000000000000000000000000006431 139.0
HFD2_k127_1569578_0 peptidase S9 - - - 2.745e-275 865.0
HFD2_k127_1569578_1 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005133 450.0
HFD2_k127_1569578_2 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 422.0
HFD2_k127_1569578_3 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000002286 232.0
HFD2_k127_1569578_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.000000000000000000000000000000000000000000000221 175.0
HFD2_k127_1569578_5 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000008528 171.0
HFD2_k127_1569578_6 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.000000004859 68.0
HFD2_k127_1575396_0 Histidine kinase K07641,K14980 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009547 357.0
HFD2_k127_1575396_1 Predicted membrane protein (DUF2339) - - - 0.0000000000000000000000000000000000000001408 168.0
HFD2_k127_1577492_0 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000204 179.0
HFD2_k127_1613598_0 phosphoesterase, PA-phosphatase related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003668 618.0
HFD2_k127_1613598_1 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000368 536.0
HFD2_k127_1613598_2 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 384.0
HFD2_k127_1613598_3 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 353.0
HFD2_k127_1613598_4 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000839 260.0
HFD2_k127_1613598_5 Molybdate ABC transporter K02018 - - 0.00000000000000000000000000000000000000000000000000000000005339 227.0
HFD2_k127_1613598_6 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.000000000000000000000000000000000000000000000000000000001378 220.0
HFD2_k127_1613598_7 Bacterial extracellular solute-binding protein K02020 - - 0.0000000000000000000000000000000000000000000000002688 199.0
HFD2_k127_1613598_8 peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000008009 180.0
HFD2_k127_1631715_0 Belongs to the malate synthase family K01638 - 2.3.3.9 5.697e-224 708.0
HFD2_k127_1631715_1 Isocitrate lyase K01637 - 4.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 613.0
HFD2_k127_1631715_10 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000005574 176.0
HFD2_k127_1631715_11 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000001219 132.0
HFD2_k127_1631715_12 peroxiredoxin activity K00627,K01607 - 2.3.1.12,4.1.1.44 0.000000000000000000002648 109.0
HFD2_k127_1631715_13 Carboxypeptidase regulatory-like domain - - - 0.000000007648 69.0
HFD2_k127_1631715_2 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001046 258.0
HFD2_k127_1631715_3 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000001112 263.0
HFD2_k127_1631715_4 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001314 254.0
HFD2_k127_1631715_5 COG0842 ABC-type multidrug transport system, permease component K01992 - - 0.0000000000000000000000000000000000000000000000000000005683 213.0
HFD2_k127_1631715_6 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000005384 206.0
HFD2_k127_1631715_7 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000104 187.0
HFD2_k127_1631715_8 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000001475 182.0
HFD2_k127_1631715_9 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000551 179.0
HFD2_k127_1634501_0 DEAD/H associated K03724 - - 0.0 1301.0
HFD2_k127_1634501_1 PFAM magnesium chelatase ChlI subunit K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 507.0
HFD2_k127_1634501_10 Methyltransferase domain - - - 0.0000003798 63.0
HFD2_k127_1634501_11 sequence-specific DNA binding K01697,K01738 GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0016020,GO:0019842,GO:0030170,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071944,GO:0097159,GO:1901363 2.5.1.47,4.2.1.22 0.0007093 49.0
HFD2_k127_1634501_2 Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 335.0
HFD2_k127_1634501_3 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000001843 211.0
HFD2_k127_1634501_4 peptidase activity - - - 0.0000000000000000000000000000000000000000000000000002474 199.0
HFD2_k127_1634501_5 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000001422 203.0
HFD2_k127_1634501_6 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000003022 152.0
HFD2_k127_1634501_7 B12 binding domain - - - 0.000000000000000000000001599 116.0
HFD2_k127_1634501_8 ATPase with chaperone activity K07391 GO:0003674,GO:0003824,GO:0004176,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0042623,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.00000000000000000006258 92.0
HFD2_k127_1634501_9 Sigma-70, region 4 - - - 0.000000000000000001589 94.0
HFD2_k127_1680088_0 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000454 228.0
HFD2_k127_1680088_1 Its participation in detoxification of cyanide may be small. May be involved in the enhancement of serine sensitivity K01011 GO:0003674,GO:0003824,GO:0004792,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009605,GO:0009987,GO:0009991,GO:0016740,GO:0016782,GO:0016783,GO:0016784,GO:0031668,GO:0033554,GO:0034641,GO:0042221,GO:0042262,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 2.8.1.1,2.8.1.2 0.0000000000000002835 87.0
HFD2_k127_1761959_0 Two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009286 436.0
HFD2_k127_1761959_1 phosphorelay sensor kinase activity K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 304.0
HFD2_k127_1761959_2 Bacterial membrane protein, YfhO - - - 0.00000000000000000000000000000000005557 155.0
HFD2_k127_1761959_3 oligosaccharyl transferase activity - - - 0.0000000000000000000000000002732 129.0
HFD2_k127_1761959_4 transcriptional regulator, winged helix family K07659 - - 0.0000000000002028 84.0
HFD2_k127_1765441_0 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 3.398e-207 657.0
HFD2_k127_1765441_1 TIGRFAM conserved repeat domain - - - 0.0006993 48.0
HFD2_k127_1766193_0 ATP-dependent DNA helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 590.0
HFD2_k127_1766193_1 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 336.0
HFD2_k127_1766193_2 Tetratricopeptide repeat - - - 0.0000004683 62.0
HFD2_k127_1770889_0 Belongs to the ClpA ClpB family K03696 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006286 305.0
HFD2_k127_1770889_1 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 317.0
HFD2_k127_1770889_10 Protein of unknown function (DUF465) K09794 - - 0.000001435 54.0
HFD2_k127_1770889_2 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000006015 239.0
HFD2_k127_1770889_3 ggdef domain - - - 0.0000000000000000000000000000000000000000000000000000000001792 223.0
HFD2_k127_1770889_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000001022 214.0
HFD2_k127_1770889_5 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000002198 187.0
HFD2_k127_1770889_6 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000002543 146.0
HFD2_k127_1770889_7 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000001977 146.0
HFD2_k127_1770889_8 Glycoprotease family K01409,K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.00000000000000000000000000000006015 134.0
HFD2_k127_1770889_9 FR47-like protein K03789 - 2.3.1.128 0.00000000000000000000000000000123 129.0
HFD2_k127_1773931_0 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 349.0
HFD2_k127_1773931_1 Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007386 304.0
HFD2_k127_1773931_10 Domain of unknown function (DUF1330) - - - 0.000000000000000000000000000001434 123.0
HFD2_k127_1773931_11 - - - - 0.0000000000000000000000000003488 121.0
HFD2_k127_1773931_12 Protocatechuate 3,4-dioxygenase beta subunit N terminal K00449 - 1.13.11.3 0.000000000002811 77.0
HFD2_k127_1773931_13 - - - - 0.0000000001276 67.0
HFD2_k127_1773931_14 Rhodanese Homology Domain - - - 0.000000007269 64.0
HFD2_k127_1773931_2 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 293.0
HFD2_k127_1773931_3 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000000000000000002012 240.0
HFD2_k127_1773931_4 Excises ethenocytosine and uracil, which can arise by alkylation or deamination of cytosine, respectively, from the corresponding mispairs with guanine in ds-DNA. It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base. The complementary strand guanine functions in substrate recognition. Required for DNA damage lesion repair in stationary-phase cells K03649 - 3.2.2.28 0.000000000000000000000000000000000000000000000000000000000000000003267 233.0
HFD2_k127_1773931_5 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000001601 210.0
HFD2_k127_1773931_6 Putative member of DMT superfamily (DUF486) - - - 0.000000000000000000000000000000000000000000000005575 177.0
HFD2_k127_1773931_7 Cupin domain - - - 0.00000000000000000000000000000000000000000004706 163.0
HFD2_k127_1773931_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000003408 152.0
HFD2_k127_1773931_9 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000002304 132.0
HFD2_k127_1793691_0 aspartate--ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004528 575.0
HFD2_k127_1793691_1 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003535 529.0
HFD2_k127_1793691_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000002383 196.0
HFD2_k127_1793691_3 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852,K18478 - 2.7.1.15,2.7.1.184 0.00000000000000000000000000000000000000000005981 174.0
HFD2_k127_1809327_0 SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556 K00239 - 1.3.5.1,1.3.5.4 1.008e-251 790.0
HFD2_k127_1809327_1 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 362.0
HFD2_k127_1809327_2 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000012 252.0
HFD2_k127_1809327_3 succinate dehydrogenase K00241 - - 0.0000000000000000000000000000000000000000000000000000000001021 210.0
HFD2_k127_1809327_4 COG2146 Ferredoxin subunits of nitrite reductase and K00363 - 1.7.1.15 0.000000000000000000000000001465 117.0
HFD2_k127_1809327_5 Domain of unknown function (DUF4135) - - - 0.000000000004641 72.0
HFD2_k127_1809327_6 TIGRFAM type 2 lantibiotic, mersacidin lichenicidin family - - - 0.000000001723 62.0
HFD2_k127_1809327_7 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0006514 49.0
HFD2_k127_1914211_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 2.66e-294 924.0
HFD2_k127_1914211_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000948 603.0
HFD2_k127_1914211_10 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000001046 63.0
HFD2_k127_1914211_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 488.0
HFD2_k127_1914211_3 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 398.0
HFD2_k127_1914211_4 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 322.0
HFD2_k127_1914211_5 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007139 298.0
HFD2_k127_1914211_6 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000001548 216.0
HFD2_k127_1914211_7 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000002959 106.0
HFD2_k127_1914211_8 PFAM Single-stranded nucleic acid binding R3H K06346 - - 0.00000000000000000000511 100.0
HFD2_k127_1914211_9 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000000005748 78.0
HFD2_k127_1946037_0 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000001107 180.0
HFD2_k127_1946037_1 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000003066 181.0
HFD2_k127_1946037_2 Membrane protein involved in the export of O-antigen and teichoic acid K03328 - - 0.000000000000000000000000000000000000000003156 175.0
HFD2_k127_1946037_3 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000002888 155.0
HFD2_k127_1946037_4 Glycosyltransferase like family 2 K20444 - - 0.0000000000000000000000000000000009964 145.0
HFD2_k127_1946037_5 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000009552 130.0
HFD2_k127_1946037_6 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000002448 113.0
HFD2_k127_1946037_7 lipolytic protein G-D-S-L family - - - 0.00000000000001167 86.0
HFD2_k127_1946037_8 ubiE/COQ5 methyltransferase family - - - 0.0000001625 62.0
HFD2_k127_1960336_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.0 1086.0
HFD2_k127_1960336_1 two-component system sensor protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 328.0
HFD2_k127_1960336_2 Dihydrodipicolinate reductase, N-terminus K21672 - 1.4.1.12,1.4.1.26 0.000000000000000000000000000000000000000000000000000000000000000006319 241.0
HFD2_k127_1960336_3 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000001046 183.0
HFD2_k127_1960336_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000002096 138.0
HFD2_k127_1990815_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008568 384.0
HFD2_k127_1990815_1 M42 glutamyl aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000002551 234.0
HFD2_k127_1990815_2 Histidine kinase HAMP - - - 0.000000000000000000002037 108.0
HFD2_k127_1990815_3 - - - - 0.000000000007719 78.0
HFD2_k127_1990815_4 Alginate export - - - 0.00005735 56.0
HFD2_k127_1994395_0 nodulation K00612 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 429.0
HFD2_k127_1994395_1 glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 317.0
HFD2_k127_1994395_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002785 285.0
HFD2_k127_2013688_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 423.0
HFD2_k127_2013688_1 Aromatic amino acid lyase K01745 - 4.3.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 349.0
HFD2_k127_2014618_0 Pfam SNARE associated Golgi protein - - - 6.293e-201 649.0
HFD2_k127_2014618_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005077 573.0
HFD2_k127_2014618_10 Methyltransferase domain - - - 0.00000003539 65.0
HFD2_k127_2014618_2 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003753 326.0
HFD2_k127_2014618_3 bifunctional purine biosynthesis protein purh K00602 GO:0003674,GO:0003824,GO:0004643,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000003614 258.0
HFD2_k127_2014618_4 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000004068 208.0
HFD2_k127_2014618_5 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000004368 126.0
HFD2_k127_2014618_6 - - - - 0.0000000000000000000832 97.0
HFD2_k127_2014618_7 methyltransferase (Contains TPR repeat) - - - 0.00000000000002854 81.0
HFD2_k127_2014618_8 Protein of unknown function (DUF1328) - - - 0.0000000000002219 72.0
HFD2_k127_2014618_9 ATPase-coupled phosphate ion transmembrane transporter activity - - - 0.000000002939 70.0
HFD2_k127_2030206_0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 323.0
HFD2_k127_2030206_1 Participates in transcription elongation, termination and antitermination K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000000001337 237.0
HFD2_k127_2030206_2 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000003093 226.0
HFD2_k127_2030206_3 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000000000000009184 178.0
HFD2_k127_2030206_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000002851 155.0
HFD2_k127_2030206_5 Ribosomal protein L33 K02913 - - 0.000000000000000000001481 94.0
HFD2_k127_2030206_6 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000007347 71.0
HFD2_k127_2030206_7 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000009081 50.0
HFD2_k127_2045468_0 PFAM ABC transporter related K16786,K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008092 413.0
HFD2_k127_2045468_1 methionyl-tRNA aminoacylation K01874 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004087 366.0
HFD2_k127_2045468_2 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 327.0
HFD2_k127_2045468_3 L-asparaginase II - - - 0.00000000000000000000000000000000000000000000000000000000000000007093 236.0
HFD2_k127_2045468_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000004403 158.0
HFD2_k127_2045468_5 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16785 - - 0.0000000000001736 84.0
HFD2_k127_2049148_0 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006366 411.0
HFD2_k127_2049148_1 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000001368 267.0
HFD2_k127_2057507_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1147.0
HFD2_k127_2057507_1 cellulose binding - - - 1.347e-283 898.0
HFD2_k127_2057507_10 Urate oxidase N-terminal - - - 0.00000000000000000000000000000000000000007986 159.0
HFD2_k127_2057507_11 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 0.000000000000000000000000000000000000001923 157.0
HFD2_k127_2057507_12 - - - - 0.00000000000001745 81.0
HFD2_k127_2057507_13 integral membrane protein K07027 - - 0.0000000001432 73.0
HFD2_k127_2057507_2 Pyridoxal-phosphate dependent enzyme K01697 - 4.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 518.0
HFD2_k127_2057507_3 glutathione-regulated potassium exporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006032 492.0
HFD2_k127_2057507_4 Protein of unknown function (DUF1343) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 437.0
HFD2_k127_2057507_5 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 354.0
HFD2_k127_2057507_6 Sir2 family K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 312.0
HFD2_k127_2057507_7 Domain of unknown function (DUF1731) K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008505 299.0
HFD2_k127_2057507_8 Polysaccharide lyase family 4, domain II - - - 0.0000000000000000000000000000000000000000000000000000161 197.0
HFD2_k127_2057507_9 photosynthesis - - - 0.0000000000000000000000000000000000000000004262 164.0
HFD2_k127_2071850_0 Abc transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000001285 228.0
HFD2_k127_2071850_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000001178 213.0
HFD2_k127_2071850_2 amine dehydrogenase activity - - - 0.0000000000000000000000000000276 136.0
HFD2_k127_2071850_3 TonB-dependent receptor K16092 - - 0.0000000009378 70.0
HFD2_k127_2074788_0 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 2.443e-225 711.0
HFD2_k127_2074788_1 Prolyl oligopeptidase family K01303 - 3.4.19.1 3.151e-224 717.0
HFD2_k127_2074788_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 456.0
HFD2_k127_2074788_3 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007966 364.0
HFD2_k127_2074788_4 Belongs to the sulfur carrier protein TusA family - - - 0.0000001087 65.0
HFD2_k127_2119721_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 509.0
HFD2_k127_2119721_1 major pilin protein fima - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005176 362.0
HFD2_k127_2119721_2 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001826 272.0
HFD2_k127_2119721_3 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000001069 178.0
HFD2_k127_2119721_4 Domain of unknown function (DUF4126) - - - 0.0000000000000004509 92.0
HFD2_k127_2173103_0 Chalcone and stilbene synthases, C-terminal domain K16167,K19580 - 2.3.1.233 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009105 391.0
HFD2_k127_2173103_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 373.0
HFD2_k127_2173103_2 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002233 275.0
HFD2_k127_2173103_3 Aminotransferase class-III - - - 0.000000000000000034 82.0
HFD2_k127_2190295_0 aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005981 420.0
HFD2_k127_2190295_1 Amidohydrolase family K01465,K06015 - 3.5.1.81,3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 302.0
HFD2_k127_2190295_2 NAD dependent epimerase/dehydratase family - - - 0.0000000000000000000000000000000000000000000000000000000000000009519 232.0
HFD2_k127_2190295_3 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000009144 206.0
HFD2_k127_2190295_4 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000006778 177.0
HFD2_k127_2190295_5 peptidoglycan binding domain - - - 0.0000000000000000000000000000000001779 142.0
HFD2_k127_2190295_6 Regulatory protein, FmdB family - - - 0.00001135 57.0
HFD2_k127_2203945_0 DNA polymerase III alpha subunit K02337,K14162 - 2.7.7.7 1.245e-195 627.0
HFD2_k127_2203945_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005285 588.0
HFD2_k127_2269823_0 radical SAM domain protein K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 558.0
HFD2_k127_2269823_1 serine-type peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 408.0
HFD2_k127_2269823_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000000000000000223 220.0
HFD2_k127_2269823_3 - - - - 0.00000000000000000000000000000000000000000000000000164 190.0
HFD2_k127_2269823_4 Belongs to the MEMO1 family K06990 - - 0.000000000000000000000000000008451 125.0
HFD2_k127_2273521_0 FtsX-like permease family K02004 - - 2.922e-209 672.0
HFD2_k127_232881_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1042.0
HFD2_k127_232881_1 Domain of unknown function (DUF3536) - - - 1.895e-316 995.0
HFD2_k127_232881_2 Alpha-amylase domain K05343 - 3.2.1.1,5.4.99.16 7.254e-207 664.0
HFD2_k127_232881_3 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700,K01236 - 2.4.1.18,3.2.1.141 6.239e-196 649.0
HFD2_k127_232881_4 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005009 582.0
HFD2_k127_232881_5 Alpha amylase, catalytic domain K06044 - 5.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 564.0
HFD2_k127_2368772_0 Peptidase M56 - - - 0.000000000000000000000000000000000007534 155.0
HFD2_k127_2368772_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000005822 127.0
HFD2_k127_2368772_2 Spermine/spermidine synthase domain - - - 0.0000001424 58.0
HFD2_k127_2398361_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 566.0
HFD2_k127_2398361_1 GTP1/OBG K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004371 394.0
HFD2_k127_2398361_10 Tetratricopeptide repeat - - - 0.00000000000000000000000000003002 133.0
HFD2_k127_2398361_11 Competence protein - - - 0.00000000000000000000000000005868 129.0
HFD2_k127_2398361_12 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000000001555 116.0
HFD2_k127_2398361_13 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000001314 115.0
HFD2_k127_2398361_14 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000002047 103.0
HFD2_k127_2398361_2 ADP-ribosylation factor family K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 304.0
HFD2_k127_2398361_3 Sigma-54 interaction domain K10943 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002571 284.0
HFD2_k127_2398361_4 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000000000002125 141.0
HFD2_k127_2398361_5 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000005028 146.0
HFD2_k127_2398361_6 Uncharacterized ACR, COG1993 K09137 - - 0.000000000000000000000000000000000006379 139.0
HFD2_k127_2398361_7 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K00969,K09710 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 2.7.7.18 0.00000000000000000000000000000001203 131.0
HFD2_k127_2398361_8 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000002072 136.0
HFD2_k127_2398361_9 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.000000000000000000000000000001327 126.0
HFD2_k127_2428289_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006471 494.0
HFD2_k127_2428289_1 ATP-dependent peptidase activity K01338,K04076,K04770,K06915 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000113 287.0
HFD2_k127_2428289_2 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000009531 266.0
HFD2_k127_2428289_3 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000001434 234.0
HFD2_k127_2428289_4 PFAM thioesterase superfamily K07107 - - 0.00000000000000000000000000000000009187 138.0
HFD2_k127_2428289_5 Tetratricopeptide repeat K05807 - - 0.00000000000000000383 96.0
HFD2_k127_2428289_6 serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.000000000000008933 85.0
HFD2_k127_2428289_7 Belongs to the ompA family K03286 - - 0.000000001254 72.0
HFD2_k127_2452767_0 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006424 479.0
HFD2_k127_2452767_1 Sortilin, neurotensin receptor 3, - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 420.0
HFD2_k127_2452767_2 SMART Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003972 382.0
HFD2_k127_2452767_3 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000167 253.0
HFD2_k127_2452767_4 Involved in the tonB-independent uptake of proteins K03641 - - 0.000000000004637 80.0
HFD2_k127_2452767_5 exo-alpha-(2->6)-sialidase activity - - - 0.0001025 49.0
HFD2_k127_2509308_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 9.379e-256 802.0
HFD2_k127_2509308_1 HlyD family secretion protein K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 330.0
HFD2_k127_2509308_10 Domain of unknown function (DUF4880) K07165 - - 0.0001202 53.0
HFD2_k127_2509308_2 Carboxypeptidase regulatory-like domain K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 325.0
HFD2_k127_2509308_3 cell redox homeostasis - - - 0.00000000000000000000000000000000000000000000000000000001627 205.0
HFD2_k127_2509308_4 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000000000000000000000000579 203.0
HFD2_k127_2509308_5 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000000000000000008782 193.0
HFD2_k127_2509308_6 outer membrane efflux protein - - - 0.00000000000000000000000000006619 133.0
HFD2_k127_2509308_7 DNA-templated transcription, initiation K03088,K03091 - - 0.00000000000000000000000001519 117.0
HFD2_k127_2509308_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000006098 83.0
HFD2_k127_2534815_0 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005694 377.0
HFD2_k127_2534815_1 Pfam 2OG-Fe(II) oxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000003747 223.0
HFD2_k127_2537529_0 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 461.0
HFD2_k127_2537529_1 protoporphyrinogen oxidase activity K01854 - 5.4.99.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 417.0
HFD2_k127_2537529_10 PFAM Glycosyl transferase, group 1 K12994 - 2.4.1.349 0.000000004258 59.0
HFD2_k127_2537529_11 type 4 fimbrial pilin related transmembrane protein K08084 - - 0.000002284 57.0
HFD2_k127_2537529_12 Pfam:N_methyl_2 - - - 0.000003572 60.0
HFD2_k127_2537529_2 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006996 351.0
HFD2_k127_2537529_3 phospho-N-acetylmuramoyl-pentapeptide-transferase activity K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 314.0
HFD2_k127_2537529_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001737 295.0
HFD2_k127_2537529_5 Glycosyltransferase like family 2 K07011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009777 253.0
HFD2_k127_2537529_6 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000005829 234.0
HFD2_k127_2537529_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000006128 231.0
HFD2_k127_2537529_8 Histidine kinase K02668,K07708 - 2.7.13.3 0.0000000000000000000000000000000000000000000002599 188.0
HFD2_k127_2537529_9 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000006279 182.0
HFD2_k127_2563540_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 0.0 1272.0
HFD2_k127_2563540_1 Peptidase dimerisation domain - - - 2.905e-209 661.0
HFD2_k127_2563540_10 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000000000000000006048 103.0
HFD2_k127_2563540_11 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.00000000000000000000217 108.0
HFD2_k127_2563540_2 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004936 607.0
HFD2_k127_2563540_3 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 607.0
HFD2_k127_2563540_4 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004099 576.0
HFD2_k127_2563540_5 nitrite transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004996 494.0
HFD2_k127_2563540_6 PFAM Alanine dehydrogenase PNT, C-terminal domain K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 380.0
HFD2_k127_2563540_7 4 iron, 4 sulfur cluster binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 296.0
HFD2_k127_2563540_8 Belongs to the peptidase S8 family K01400,K01417,K20274 - 3.4.24.28 0.000000000000000000000000000000000000000000000007714 198.0
HFD2_k127_2563540_9 - K00003,K00058,K01754,K04517,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,1.3.1.12,4.3.1.19 0.00000000000000000000000000000000000000000001467 169.0
HFD2_k127_2572038_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 572.0
HFD2_k127_2572038_1 Ftsk_gamma K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005407 606.0
HFD2_k127_2572038_10 PilZ domain - - - 0.000000000000000000000004162 111.0
HFD2_k127_2572038_11 peptidyl-tyrosine sulfation - - - 0.00000007019 66.0
HFD2_k127_2572038_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000111 258.0
HFD2_k127_2572038_3 O-acyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000001215 241.0
HFD2_k127_2572038_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000155 218.0
HFD2_k127_2572038_5 Bacterial membrane protein, YfhO - - - 0.000000000000000000000000000000000000000000001544 189.0
HFD2_k127_2572038_6 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000005715 175.0
HFD2_k127_2572038_7 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000002715 160.0
HFD2_k127_2572038_8 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.0000000000000000000000000000000007638 133.0
HFD2_k127_2572038_9 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.0000000000000000000000000005669 117.0
HFD2_k127_2591976_0 Cytochrome C assembly protein K02198,K04016 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0020037,GO:0022607,GO:0031224,GO:0031226,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000448 608.0
HFD2_k127_2591976_1 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006395 520.0
HFD2_k127_2591976_10 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.000000000000000000000002178 109.0
HFD2_k127_2591976_11 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000005836 93.0
HFD2_k127_2591976_12 transcriptional regulator K07666,K07774 - - 0.000000001558 68.0
HFD2_k127_2591976_13 Cytochrome c-type biogenesis protein K02198 - - 0.000000009939 64.0
HFD2_k127_2591976_14 Domain of unknown function (DUF4388) - - - 0.00000003017 67.0
HFD2_k127_2591976_2 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 481.0
HFD2_k127_2591976_3 ABC transporter K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000000000000000000000000007606 233.0
HFD2_k127_2591976_4 Cytochrome C assembly protein K02195 - - 0.00000000000000000000000000000000000000000000000000000000000000001671 231.0
HFD2_k127_2591976_5 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000008206 219.0
HFD2_k127_2591976_6 PFAM cytochrome c-type biogenesis protein CcmB K02194 - - 0.00000000000000000000000000000000000000000007133 178.0
HFD2_k127_2591976_7 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000001523 178.0
HFD2_k127_2591976_8 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000101 156.0
HFD2_k127_2591976_9 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000007733 147.0
HFD2_k127_2636382_0 GTP-binding protein TypA K06207 - - 1.213e-251 789.0
HFD2_k127_2636382_1 Alpha/beta hydrolase family K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006261 513.0
HFD2_k127_2636382_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 429.0
HFD2_k127_2636382_3 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000000000000000000000000006399 224.0
HFD2_k127_2636382_4 EamA-like transporter family - - - 0.000000000000000000000000000000000000979 151.0
HFD2_k127_2636382_5 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000000000000000005045 113.0
HFD2_k127_2636382_6 oxidoreductase activity K00337,K03333,K04771,K07114 - 1.1.3.6,1.6.5.3,3.4.21.107 0.00000000000000000009589 106.0
HFD2_k127_2636382_7 Protein involved in outer membrane biogenesis K07289,K07290 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0032386,GO:0032879,GO:0032880,GO:0033157,GO:0044464,GO:0050789,GO:0051049,GO:0051223,GO:0060341,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:0090313,GO:1903533,GO:1903827,GO:1905475 - 0.00000000000000000217 101.0
HFD2_k127_2636382_8 Protein of unknown function (DUF3788) - - - 0.0000000000000004766 84.0
HFD2_k127_2636382_9 AsmA-like C-terminal region K07289 - - 0.00000000000635 80.0
HFD2_k127_264925_0 COG1651 Protein-disulfide isomerase K21990 - - 0.000000000000000000000000000001382 126.0
HFD2_k127_264925_1 Cytochrome c554 and c-prime K10535 - 1.7.2.6 0.00000000000000000002171 100.0
HFD2_k127_264925_2 metal cluster binding K06940,K18475 - - 0.000000000000004801 84.0
HFD2_k127_264925_3 Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c - GO:0008150,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840 - 0.00000000002722 75.0
HFD2_k127_2695217_0 Psort location Cytoplasmic, score K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003593 552.0
HFD2_k127_2695217_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001106 248.0
HFD2_k127_2695217_2 - - - - 0.000000000006319 74.0
HFD2_k127_2695217_3 peptidyl-tyrosine sulfation - - - 0.00000005093 65.0
HFD2_k127_2727847_0 Predicted membrane protein (DUF2238) K08984 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003035 269.0
HFD2_k127_2727847_1 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000002245 261.0
HFD2_k127_2727847_2 DNA photolyase K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000002003 222.0
HFD2_k127_2751637_0 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 400.0
HFD2_k127_2751637_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 344.0
HFD2_k127_2751637_2 - - - - 0.0005067 45.0
HFD2_k127_275372_0 Deoxyribodipyrimidine photo-lyase K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 583.0
HFD2_k127_275372_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 414.0
HFD2_k127_275372_2 PFAM YbbR family protein - - - 0.0000008717 57.0
HFD2_k127_2770073_0 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000001071 195.0
HFD2_k127_2778366_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000608 430.0
HFD2_k127_2778366_1 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 415.0
HFD2_k127_2778366_2 Sigma-54 interaction domain K07714,K07715 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007055 379.0
HFD2_k127_2778366_3 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000887 368.0
HFD2_k127_2778366_4 Phosphate acetyl/butaryl transferase K00625 - 2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 311.0
HFD2_k127_2778366_5 Molybdenum cofactor synthesis domain protein K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001668 278.0
HFD2_k127_2778366_6 TatD family K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000005433 234.0
HFD2_k127_2778366_7 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000007873 227.0
HFD2_k127_2778366_8 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000007236 199.0
HFD2_k127_2778366_9 Glycosyl transferase, family 2 K01002,K20534 - 2.7.8.20 0.0000000000000000000000000000000000000000005402 175.0
HFD2_k127_2779964_0 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005368 580.0
HFD2_k127_2793305_0 Pfam:KaiC K08482 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005987 599.0
HFD2_k127_2793305_1 catalyzes the conversion of acetate and CoA to acetyl-CoA K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 573.0
HFD2_k127_2793305_10 4'-phosphopantetheinyl transferase superfamily K00997 - 2.7.8.7 0.0000000000000000000000000001823 119.0
HFD2_k127_2793305_11 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.000000000000000000000000001017 117.0
HFD2_k127_2793305_12 Putative Flp pilus-assembly TadE/G-like - - - 0.0000000000000000000000006989 123.0
HFD2_k127_2793305_13 Thioredoxin K03671 - - 0.00000000000000000003198 98.0
HFD2_k127_2793305_2 Nickel-dependent hydrogenase K00436 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008167 450.0
HFD2_k127_2793305_3 PFAM Thiolase K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005023 437.0
HFD2_k127_2793305_4 4Fe-4S dicluster domain K16950 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 432.0
HFD2_k127_2793305_5 synthase K01641 - 2.3.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 421.0
HFD2_k127_2793305_6 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 382.0
HFD2_k127_2793305_7 Coenzyme F420-reducing hydrogenase, gamma subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004724 364.0
HFD2_k127_2793305_8 2 iron, 2 sulfur cluster binding K02823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 350.0
HFD2_k127_2793305_9 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.00000000000000000000000000000000000000000000002629 174.0
HFD2_k127_2819490_0 Peptidase family M49 - - - 1.718e-204 651.0
HFD2_k127_2854655_0 2-oxoglutarate dehydrogenase, E1 K00164 - 1.2.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 619.0
HFD2_k127_2854655_1 Pkd domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 540.0
HFD2_k127_2854655_10 oxidoreductase activity - - - 0.0000000001238 76.0
HFD2_k127_2854655_11 Oxidoreductase molybdopterin binding - - - 0.0001892 51.0
HFD2_k127_2854655_2 Permease family K06901 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 419.0
HFD2_k127_2854655_3 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006157 315.0
HFD2_k127_2854655_4 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000000001252 205.0
HFD2_k127_2854655_5 Amidase - - - 0.0000000000000000000000000000000000000000008752 166.0
HFD2_k127_2854655_6 Glycine cleavage T-protein C-terminal barrel domain K00605,K06980 - 2.1.2.10 0.000000000000000000000000000000000000000001017 177.0
HFD2_k127_2854655_7 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000003976 143.0
HFD2_k127_2854655_8 PFAM Dienelactone hydrolase - - - 0.000000000000005108 87.0
HFD2_k127_2854655_9 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000002524 76.0
HFD2_k127_2882211_0 Heat shock 70 kDa protein K04043 - - 8.762e-236 745.0
HFD2_k127_2882211_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007078 396.0
HFD2_k127_2882211_10 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000004628 124.0
HFD2_k127_2882211_11 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000005035 108.0
HFD2_k127_2882211_12 protein conserved in bacteria K03749 - - 0.0004154 50.0
HFD2_k127_2882211_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 371.0
HFD2_k127_2882211_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005651 357.0
HFD2_k127_2882211_4 PFAM Band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003689 337.0
HFD2_k127_2882211_5 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005816 323.0
HFD2_k127_2882211_6 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005659 316.0
HFD2_k127_2882211_7 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001146 277.0
HFD2_k127_2882211_8 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000002939 147.0
HFD2_k127_2882211_9 Ribosomal protein L11 methyltransferase K02687 - - 0.0000000000000000000000000000007384 132.0
HFD2_k127_2972500_0 transferase activity, transferring glycosyl groups K03271 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008968,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016853,GO:0016866,GO:0016868,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 486.0
HFD2_k127_2972500_1 nodulation K00612 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 398.0
HFD2_k127_2972500_2 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000000000000000000000000000000000000146 184.0
HFD2_k127_2975862_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0002161,GO:0002196,GO:0003674,GO:0003700,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006355,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009451,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:0140110,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.1.1.7 1.438e-264 841.0
HFD2_k127_2975862_1 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008466 523.0
HFD2_k127_2975862_2 Adenosine/AMP deaminase K01488,K18286 - 3.5.4.4,3.5.4.40 0.00000000000000000000000000000000000000000000000000548 202.0
HFD2_k127_2975862_3 PFAM Transglycosylase SLT domain K08309 - - 0.00000000000000000000000000000000002231 150.0
HFD2_k127_2975862_4 RecX family K03565 - - 0.0000002658 62.0
HFD2_k127_2994219_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 547.0
HFD2_k127_2994219_1 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 389.0
HFD2_k127_2994219_2 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein - - - 0.00000000000000000000000000000000000000000000000000000000009844 218.0
HFD2_k127_2994219_3 Protein of unknown function (DUF3570) - - - 0.00000000000000000000000000000007511 139.0
HFD2_k127_2994219_4 Redoxin domain protein - - - 0.00000000000000000000000005407 118.0
HFD2_k127_2994219_5 ADP binding - - - 0.0000000000000000000000001146 111.0
HFD2_k127_2994219_6 Sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000282 84.0
HFD2_k127_3012918_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.517e-240 751.0
HFD2_k127_3012918_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 1.924e-214 674.0
HFD2_k127_3012918_10 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000003296 122.0
HFD2_k127_3012918_11 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000004227 114.0
HFD2_k127_3012918_12 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000002561 108.0
HFD2_k127_3012918_2 PFAM Cobyrinic acid ac-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008563 313.0
HFD2_k127_3012918_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007353 301.0
HFD2_k127_3012918_4 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000001641 247.0
HFD2_k127_3012918_5 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000009422 242.0
HFD2_k127_3012918_6 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000001871 216.0
HFD2_k127_3012918_7 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000000003874 185.0
HFD2_k127_3012918_8 negative regulation of transcription, DNA-templated K10947 - - 0.0000000000000000000000000000000000461 138.0
HFD2_k127_3012918_9 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000001089 130.0
HFD2_k127_302198_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007015 527.0
HFD2_k127_302198_1 Peptidase family M49 K01277 - 3.4.14.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 538.0
HFD2_k127_302198_2 PPIC-type PPIASE domain K07533 - 5.2.1.8 0.0000001214 60.0
HFD2_k127_3030334_0 UDP binding domain K02474,K13015 - 1.1.1.136 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 556.0
HFD2_k127_3030334_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 536.0
HFD2_k127_3030334_10 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000002128 199.0
HFD2_k127_3030334_11 transferase activity, transferring glycosyl groups K00754,K19422 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.0000000000000000000000000000000000000000000000004676 190.0
HFD2_k127_3030334_12 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000008614 175.0
HFD2_k127_3030334_13 O-Antigen ligase K02847 - - 0.0000000000000000000000000000000000000000001664 178.0
HFD2_k127_3030334_14 dTDP biosynthetic process K00560,K00943 - 2.1.1.45,2.7.4.9 0.0000000000000000000000000000000000000000008582 177.0
HFD2_k127_3030334_15 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.00000000000000000000000000000000004129 149.0
HFD2_k127_3030334_16 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.000000000000000000000000000001375 123.0
HFD2_k127_3030334_17 methyltransferase - - - 0.00000000000000000000000000106 126.0
HFD2_k127_3030334_18 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000001182 98.0
HFD2_k127_3030334_19 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000391 73.0
HFD2_k127_3030334_2 Male sterility protein K08679 - 5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004827 391.0
HFD2_k127_3030334_3 short-chain dehydrogenase reductase SDR K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 370.0
HFD2_k127_3030334_4 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005347 309.0
HFD2_k127_3030334_5 Mannose-6-phosphate isomerase K00971 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002348 289.0
HFD2_k127_3030334_6 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001634 292.0
HFD2_k127_3030334_7 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001855 262.0
HFD2_k127_3030334_8 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003881 246.0
HFD2_k127_3030334_9 PFAM glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000006546 237.0
HFD2_k127_3109492_0 Zinc carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 595.0
HFD2_k127_3109492_1 metallopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000003329 212.0
HFD2_k127_3109492_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000004127 168.0
HFD2_k127_3109492_3 bacterial (prokaryotic) histone like domain K03530 - - 0.0000000000000000000000003681 109.0
HFD2_k127_3109492_4 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000000000003131 105.0
HFD2_k127_3109492_5 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.00000000000000000000007208 107.0
HFD2_k127_3109492_6 Cytochrome C oxidase, cbb3-type, subunit III K19713 - 1.8.2.2 0.00000000394 67.0
HFD2_k127_3109492_7 C4-type zinc ribbon domain K07164 - - 0.00002103 55.0
HFD2_k127_3131075_0 Malic enzyme, NAD binding domain K00027,K00029,K00625,K13788 GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114 1.1.1.38,1.1.1.40,2.3.1.8 7.89e-294 939.0
HFD2_k127_3131075_1 Cytochrome C assembly protein - - - 2.943e-245 779.0
HFD2_k127_3131075_10 Cytochrome c554 and c-prime K03620 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000821 333.0
HFD2_k127_3131075_11 Protoglobin - GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005515,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0019825,GO:0020037,GO:0023014,GO:0023052,GO:0035556,GO:0036094,GO:0036211,GO:0042802,GO:0042803,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046906,GO:0046983,GO:0048037,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0097159,GO:0140096,GO:1901363,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000001425 233.0
HFD2_k127_3131075_12 Cytochrome c554 and c-prime K03620 - - 0.00000000000000000000000000000000000000000000000000000000000008471 239.0
HFD2_k127_3131075_13 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.0000000000000000000000000000000000000000000000001764 183.0
HFD2_k127_3131075_14 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000001042 181.0
HFD2_k127_3131075_15 Cytochrome b/b6/petB K00412,K03888 - - 0.00000000000000000000000000000000000000000004318 177.0
HFD2_k127_3131075_16 amine dehydrogenase activity K21449 - - 0.0000000000000000000000000000000000000006344 155.0
HFD2_k127_3131075_17 Alginate export - - - 0.000000000000000000000000000000000000004072 163.0
HFD2_k127_3131075_18 AMP binding - - - 0.00000000000000000000000000000144 126.0
HFD2_k127_3131075_19 RDD family - - - 0.00000000000000000000004924 109.0
HFD2_k127_3131075_2 formate dehydrogenase - - - 3.578e-245 781.0
HFD2_k127_3131075_20 PFAM Rieske 2Fe-2S K02636 - 1.10.9.1 0.00000000000000002417 88.0
HFD2_k127_3131075_21 helix_turn_helix, Lux Regulon - - - 0.00000000000477 75.0
HFD2_k127_3131075_23 response regulator K02481,K07713 - - 0.00000000003266 66.0
HFD2_k127_3131075_25 - - - - 0.00003424 53.0
HFD2_k127_3131075_26 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein K00176 - 1.2.7.3 0.0001353 49.0
HFD2_k127_3131075_3 peptidyl-tyrosine sulfation - - - 7.139e-205 652.0
HFD2_k127_3131075_4 Domains REC, sigma54 interaction, HTH8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 483.0
HFD2_k127_3131075_5 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005374 445.0
HFD2_k127_3131075_6 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 371.0
HFD2_k127_3131075_7 Aldo Keto reductase K07079 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 338.0
HFD2_k127_3131075_8 denitrification pathway K02569,K15876 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 347.0
HFD2_k127_3131075_9 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 326.0
HFD2_k127_317061_0 NADH:flavin oxidoreductase / NADH oxidase family K09461 - 1.14.13.40 6.727e-264 837.0
HFD2_k127_317061_1 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 573.0
HFD2_k127_317061_2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004593 510.0
HFD2_k127_317061_3 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007553 503.0
HFD2_k127_317061_4 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 422.0
HFD2_k127_317061_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 319.0
HFD2_k127_317061_6 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008762 305.0
HFD2_k127_317061_7 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003405 278.0
HFD2_k127_317061_8 Secretion protein K01993 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0071944 - 0.00000000000000000000000000000000000000000000000000001573 200.0
HFD2_k127_3173388_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00322,K00382 - 1.6.1.1,1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 522.0
HFD2_k127_3173388_1 thiamine diphosphate biosynthetic process K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 377.0
HFD2_k127_3173388_10 Thiazole synthase-like - - - 0.00000000004658 73.0
HFD2_k127_3173388_2 Domain of unknown function (DUF4162) K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007319 340.0
HFD2_k127_3173388_3 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses K01916 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009027 327.0
HFD2_k127_3173388_4 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003911 246.0
HFD2_k127_3173388_5 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000001186 256.0
HFD2_k127_3173388_6 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000115 228.0
HFD2_k127_3173388_7 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000008992 218.0
HFD2_k127_3173388_8 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.0000000000000000000000000000000000000000000001303 174.0
HFD2_k127_3173388_9 - - - - 0.000000000000000000000005012 113.0
HFD2_k127_3178319_0 Pterin binding enzyme K00548,K15023 - 2.1.1.13,2.1.1.258 6.352e-305 964.0
HFD2_k127_3178319_1 Predicted membrane protein (DUF2238) K08984 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003799 317.0
HFD2_k127_3178319_10 peptidyl-tyrosine sulfation - - - 0.000111 54.0
HFD2_k127_3178319_2 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003244 267.0
HFD2_k127_3178319_3 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000001467 256.0
HFD2_k127_3178319_4 methionine synthase K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000001426 222.0
HFD2_k127_3178319_5 von Willebrand factor, type A - - - 0.00000000000000000000000000845 125.0
HFD2_k127_3178319_6 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000132 68.0
HFD2_k127_3178319_7 Transcriptional regulatory protein, C terminal - - - 0.0000001109 62.0
HFD2_k127_3178319_8 peptidyl-tyrosine sulfation - - - 0.000002045 58.0
HFD2_k127_3179946_0 Fungalysin metallopeptidase (M36) - - - 0.0 1098.0
HFD2_k127_3179946_1 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 490.0
HFD2_k127_3179946_3 COG1228 Imidazolonepropionase and related amidohydrolases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009928 329.0
HFD2_k127_3179946_4 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007449 260.0
HFD2_k127_3179946_5 EamA-like transporter family - - - 0.000000000000000000000000000000000000000001239 169.0
HFD2_k127_3179946_6 Cys/Met metabolism PLP-dependent enzyme K01739,K01761 - 2.5.1.48,4.4.1.11 0.0000000000000000000000000000000000001187 143.0
HFD2_k127_3179946_7 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000312 144.0
HFD2_k127_3179946_8 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000161 137.0
HFD2_k127_3179946_9 Cysteine-rich secretory protein family - - - 0.000000000000000000000005132 113.0
HFD2_k127_3223476_0 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000007288 246.0
HFD2_k127_3223476_1 Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000003573 214.0
HFD2_k127_3223476_2 glycosyl transferase family 39 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000001565 196.0
HFD2_k127_3223476_3 serine threonine protein kinase - - - 0.00001771 57.0
HFD2_k127_3240265_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 9.542e-209 658.0
HFD2_k127_3240265_1 Tricorn protease C1 domain K08676 - - 2.349e-202 672.0
HFD2_k127_3240265_10 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00966,K00973,K00992 GO:0000166,GO:0000270,GO:0000287,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0005488,GO:0006022,GO:0006040,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019752,GO:0030203,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044281,GO:0046872,GO:0070569,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.7.13,2.7.7.24,2.7.7.99 0.00000000000000000000000000000000000000000001763 179.0
HFD2_k127_3240265_11 PFAM SWIB MDM2 domain - - - 0.00000000000000000000000000000000005967 135.0
HFD2_k127_3240265_12 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000004216 138.0
HFD2_k127_3240265_13 CYTH K05873 - 4.6.1.1 0.000000000000000000000000004597 119.0
HFD2_k127_3240265_14 Cold-shock protein K03704 - - 0.00000000000000000000000009201 109.0
HFD2_k127_3240265_15 amine dehydrogenase activity K14647,K21449 - - 0.0000000000000000000000005177 121.0
HFD2_k127_3240265_16 von Willebrand factor, type A K07114 - - 0.00000000000002518 85.0
HFD2_k127_3240265_17 Putative metal-binding motif - - - 0.00000000000005873 85.0
HFD2_k127_3240265_18 Tetratricopeptide repeat - - - 0.000000005132 70.0
HFD2_k127_3240265_19 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms K14205 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.2.3 0.00000006323 64.0
HFD2_k127_3240265_2 calcium, potassium:sodium antiporter activity K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005727 379.0
HFD2_k127_3240265_20 salt-induced outer membrane protein - - - 0.0001932 53.0
HFD2_k127_3240265_3 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007374 311.0
HFD2_k127_3240265_4 PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP K20276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006136 291.0
HFD2_k127_3240265_5 Podospora anserina S mat genomic DNA chromosome - - - 0.00000000000000000000000000000000000000000000000000000000000000000007641 248.0
HFD2_k127_3240265_6 Metallopeptidase family M24 - - - 0.00000000000000000000000000000000000000000000000000000000000000001258 241.0
HFD2_k127_3240265_7 Putative modulator of DNA gyrase K03568 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000009371 211.0
HFD2_k127_3240265_8 phosphotransferase related to Ser Thr protein kinases K07102 - 2.7.1.221 0.0000000000000000000000000000000000000000000000000005232 203.0
HFD2_k127_3240265_9 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000006984 186.0
HFD2_k127_3246312_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008819 555.0
HFD2_k127_3246312_1 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005677 315.0
HFD2_k127_3246312_2 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000514 248.0
HFD2_k127_3246312_3 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.0002762 51.0
HFD2_k127_3252363_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 615.0
HFD2_k127_3252363_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00282 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006807,GO:0008150,GO:0008152,GO:0009069,GO:0009987,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019752,GO:0032991,GO:0042133,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901605,GO:1902494,GO:1990204 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007323 466.0
HFD2_k127_3252363_2 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005065 416.0
HFD2_k127_3252363_3 Belongs to the peptidase S51 family K05995 GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 3.4.13.21 0.00000000000000000000000000000000000000000000000000000000000000000000007567 250.0
HFD2_k127_3252363_4 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000006489 174.0
HFD2_k127_3252363_5 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000004159 165.0
HFD2_k127_3252363_6 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02504,K02652 - - 0.000000000000000000000000000000000004967 157.0
HFD2_k127_3252363_7 nucleotide catabolic process - - - 0.0000000000000000000000001121 120.0
HFD2_k127_3252363_8 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.000000000000000000001088 99.0
HFD2_k127_3252363_9 Histidine kinase K01768,K12132 - 2.7.11.1,4.6.1.1 0.00000000000000000001221 94.0
HFD2_k127_3296519_0 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 540.0
HFD2_k127_3296519_1 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 392.0
HFD2_k127_3296519_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000001483 201.0
HFD2_k127_3296519_3 - - - - 0.000000000000000000000000000000001577 147.0
HFD2_k127_3296519_5 COG0695 Glutaredoxin and related proteins - - - 0.000000000008427 71.0
HFD2_k127_3322150_0 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004079 415.0
HFD2_k127_3322150_1 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 374.0
HFD2_k127_3322150_2 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000001834 207.0
HFD2_k127_3322150_3 MeTHIonine synthase K00548 - 2.1.1.13 0.000000000000000000003311 105.0
HFD2_k127_3322150_4 PFAM Vitamin B12 dependent methionine synthase, activation - - - 0.0000000000000003593 87.0
HFD2_k127_33328_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000000000000000000000000000000000000000000000000000000005677 211.0
HFD2_k127_33328_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000003381 133.0
HFD2_k127_33328_2 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749,K04757 - 2.7.11.1 0.000000000000808 74.0
HFD2_k127_33328_3 antisigma factor binding K04749 - - 0.0000000001073 68.0
HFD2_k127_3380145_0 Peptidase family M3 K01284 - 3.4.15.5 0.0 1045.0
HFD2_k127_3380145_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 450.0
HFD2_k127_3380145_2 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008741 443.0
HFD2_k127_3380145_3 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005412 398.0
HFD2_k127_3380145_4 response regulator - - - 0.00000000000000000000000000000000000000000000000001084 201.0
HFD2_k127_3380145_5 oligosaccharyl transferase activity - - - 0.00000000000000000000000000000000002334 153.0
HFD2_k127_3381324_0 TIGRFAM methylmalonyl-CoA mutase, large subunit K01848 - 5.4.99.2 1.756e-233 735.0
HFD2_k127_3381324_1 acyl-CoA dehydrogenase activity K00248,K00249 - 1.3.8.1,1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 416.0
HFD2_k127_3381324_2 RNA polymerase sigma-54 factor K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000954 406.0
HFD2_k127_3381324_3 Acyl-CoA dehydrogenase, N-terminal domain K18244 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004344 291.0
HFD2_k127_3381324_4 B12 binding domain K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000008685 193.0
HFD2_k127_3381324_5 ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000004454 168.0
HFD2_k127_3381324_6 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.00000000000000000000000000000000418 137.0
HFD2_k127_3381324_7 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000331 138.0
HFD2_k127_3381324_8 Acyl-CoA dehydrogenase, N-terminal - - - 0.00000000000000000000000000006646 120.0
HFD2_k127_3424208_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 343.0
HFD2_k127_3424208_1 C-terminal four TMM region of protein-O-mannosyltransferase - - - 0.0000000000000000002437 102.0
HFD2_k127_3464216_0 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 452.0
HFD2_k127_3464216_1 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002978 433.0
HFD2_k127_3464216_2 endonuclease activity K07451 - - 0.000000000001756 81.0
HFD2_k127_3464216_3 Tetratricopeptide repeat - - - 0.000454 52.0
HFD2_k127_3481849_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.572e-209 669.0
HFD2_k127_3481849_1 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000434 201.0
HFD2_k127_3481849_2 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000004888 151.0
HFD2_k127_3481849_3 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000001033 152.0
HFD2_k127_3481849_4 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000001179 88.0
HFD2_k127_3481849_5 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0001427 48.0
HFD2_k127_3541642_0 xanthine dehydrogenase activity K04108 - 1.3.7.9 2.476e-213 696.0
HFD2_k127_3541642_1 aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007139 499.0
HFD2_k127_3541642_2 ATP-dependent DNA helicase RecG K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009259 450.0
HFD2_k127_3541642_3 CO dehydrogenase flavoprotein C-terminal domain K04109 - 1.3.7.9 0.0000000000000000000000000000000000000000000000000000000000000006069 233.0
HFD2_k127_3541642_4 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000002712 197.0
HFD2_k127_3541642_5 Domain of unknown function (DUF4388) K03413 - - 0.0000000000000000000000000000000000000005895 162.0
HFD2_k127_3541642_6 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.000000000000000000000000001431 123.0
HFD2_k127_3541642_7 Protein conserved in bacteria - - - 0.000001321 61.0
HFD2_k127_3587337_0 Family 5 K02035,K15580 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005608 312.0
HFD2_k127_3587337_1 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000000000000000005113 216.0
HFD2_k127_3587337_2 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.000000000000000000000000000000000000000000000000000001336 203.0
HFD2_k127_3587337_3 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000009645 199.0
HFD2_k127_3587337_4 ethanolamine catabolic process K04027 - - 0.000000000000000000000000000000000003847 139.0
HFD2_k127_3587337_5 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028,K08697 - - 0.0000000000000000000000005824 106.0
HFD2_k127_3587337_6 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - 0.000000000000000227 81.0
HFD2_k127_3587337_7 Ethanolamine utilisation protein EutN/carboxysome K04028 - - 0.0000000005687 70.0
HFD2_k127_3587337_8 Tetratricopeptide repeats - - - 0.00000002176 63.0
HFD2_k127_3587337_9 Tetratricopeptide repeat - - - 0.000000535 60.0
HFD2_k127_3589315_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.268e-216 693.0
HFD2_k127_3589315_1 ABC transporter transmembrane region K06147,K18890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 576.0
HFD2_k127_3589315_2 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.00000000000000000000000000000000000000000000000000000000000000000007499 254.0
HFD2_k127_3589315_3 Beta-lactamase superfamily domain K06136 - - 0.000000000000000000000000000000000000000003453 160.0
HFD2_k127_3589315_4 ABC-type multidrug transport system ATPase and permease K18889 - - 0.0000000000000000000001381 99.0
HFD2_k127_3590067_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K07306,K17050 - 1.7.5.1,1.8.5.3 0.0 1363.0
HFD2_k127_3590067_1 PFAM Cytochrome b b6 domain - - - 7.924e-202 654.0
HFD2_k127_3590067_2 nitrate reductase beta subunit K00371,K17051 - 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 558.0
HFD2_k127_3590067_3 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 314.0
HFD2_k127_3590067_4 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001907 297.0
HFD2_k127_3590067_5 chaperone-mediated protein complex assembly K00373,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.00000000000000000000000000004345 135.0
HFD2_k127_3590067_6 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.000000000000000000000009226 117.0
HFD2_k127_3590067_7 chaperone-mediated protein complex assembly - - - 0.0000003997 61.0
HFD2_k127_3634931_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003993 420.0
HFD2_k127_3634931_1 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 353.0
HFD2_k127_3634931_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 346.0
HFD2_k127_3634931_3 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000535 319.0
HFD2_k127_3634931_4 Protein of unknown function (DUF2400) K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001799 310.0
HFD2_k127_3634931_5 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000806 283.0
HFD2_k127_3634931_6 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000003773 239.0
HFD2_k127_3634931_7 Psort location CytoplasmicMembrane, score - - - 0.00000001267 68.0
HFD2_k127_3649852_0 Pfam:KaiC K08482 - - 2.653e-203 648.0
HFD2_k127_3649852_1 KaiB K08481 - - 0.00000000000000000000000000000004403 132.0
HFD2_k127_3649852_2 COG0642 Signal transduction histidine kinase - - - 0.000000000000000000000000000002259 123.0
HFD2_k127_3649852_3 KaiB K08481 - - 0.000000000000000000000000001727 119.0
HFD2_k127_3670492_0 FtsX-like permease family K02004 - - 6.624e-246 786.0
HFD2_k127_3670492_1 COG0308 Aminopeptidase N - - - 2.926e-216 693.0
HFD2_k127_3670492_10 - - - - 0.0000000000000000000000000000012 136.0
HFD2_k127_3670492_11 Domain of unknown function (DUF4115) K15539 - - 0.000000000000005149 87.0
HFD2_k127_3670492_12 - - - - 0.00000000000006296 79.0
HFD2_k127_3670492_13 TonB-dependent receptor - - - 0.0001888 54.0
HFD2_k127_3670492_2 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 454.0
HFD2_k127_3670492_3 Lipocalin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 434.0
HFD2_k127_3670492_4 PKD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003417 332.0
HFD2_k127_3670492_5 COG0076 Glutamate decarboxylase and related PLP-dependent proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005055 318.0
HFD2_k127_3670492_6 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001775 276.0
HFD2_k127_3670492_7 Protein serine threonine phosphatase K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000006694 238.0
HFD2_k127_3670492_8 Selenoprotein B glycine betaine sarcosine D-proline reductase K10794 - 1.21.4.1 0.00000000000000000000000000000000005842 143.0
HFD2_k127_3673070_0 Pfam:KaiC K08482 - - 4.841e-205 655.0
HFD2_k127_3673070_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 386.0
HFD2_k127_3673070_2 PAS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002815 269.0
HFD2_k127_3673070_3 PAS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000002622 252.0
HFD2_k127_3673070_4 Sortase family K07284 - 3.4.22.70 0.00000000000000000000000000000000000001328 155.0
HFD2_k127_3673070_5 KaiB K08481 - - 0.0000000000000000000000000000001512 142.0
HFD2_k127_3673070_6 PFAM KaiB domain protein K08481 - - 0.00000000000000000000005398 102.0
HFD2_k127_3673070_7 copper-translocating P-type ATPase K17686 - 3.6.3.54 0.000000001887 62.0
HFD2_k127_3678742_0 PFAM glycosyl hydrolase BNR repeat-containing protein - - - 0.0 1114.0
HFD2_k127_3678742_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004318 481.0
HFD2_k127_3678742_10 domain protein - - - 0.0000000772 66.0
HFD2_k127_3678742_11 Belongs to the glycosyl hydrolase 28 family - - - 0.00007643 56.0
HFD2_k127_3678742_12 COG0457 FOG TPR repeat - - - 0.0003837 53.0
HFD2_k127_3678742_2 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 335.0
HFD2_k127_3678742_4 Transglycosylase SLT domain K08307,K12204 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005329 306.0
HFD2_k127_3678742_5 RNase_H superfamily K07502 - - 0.00000000000000000000000000000000000000000000000000000000001595 216.0
HFD2_k127_3678742_6 - K14340 - - 0.000000000000000000000000000000000000000000000102 191.0
HFD2_k127_3678742_7 Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000008295 137.0
HFD2_k127_3678742_8 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000004829 145.0
HFD2_k127_3678742_9 O-Antigen ligase - - - 0.0000000000001366 83.0
HFD2_k127_3689774_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.797e-208 668.0
HFD2_k127_3689774_1 Peptidase S9 prolyl oligopeptidase active site - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 584.0
HFD2_k127_3689774_10 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.00000000000000000000000000000000000000000000000001826 186.0
HFD2_k127_3689774_11 DJ-1/PfpI family - - - 0.00000000000000000000000000000000000000000001594 171.0
HFD2_k127_3689774_12 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.000000000000000000000000000000000001418 142.0
HFD2_k127_3689774_13 Belongs to the UPF0200 family - - - 0.0000000000000000002179 99.0
HFD2_k127_3689774_14 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K21142 - 2.8.1.12 0.0000000000001123 74.0
HFD2_k127_3689774_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 436.0
HFD2_k127_3689774_3 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 394.0
HFD2_k127_3689774_4 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005216 385.0
HFD2_k127_3689774_5 RelA SpoT domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002086 252.0
HFD2_k127_3689774_6 (Rhomboid) family K07059 - - 0.000000000000000000000000000000000000000000000000000000000000005041 224.0
HFD2_k127_3689774_7 DHH family K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000061 223.0
HFD2_k127_3689774_8 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000004657 221.0
HFD2_k127_3689774_9 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.000000000000000000000000000000000000000000000000000001766 196.0
HFD2_k127_3704053_0 3-isopropylmalate dehydratase activity K01703,K01704,K01705 - 4.2.1.33,4.2.1.35,4.2.1.36 2.441e-290 903.0
HFD2_k127_3704053_1 citrate CoA-transferase activity K01643 - 2.8.3.10 1.644e-244 782.0
HFD2_k127_3704053_10 PFAM Cold-shock K03704 - - 0.0000000000000000000000003066 111.0
HFD2_k127_3704053_11 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.0000000000000000000003005 109.0
HFD2_k127_3704053_12 - - - - 0.000003133 55.0
HFD2_k127_3704053_2 MmgE/PrpD family K01720 - 4.2.1.79 1.206e-205 657.0
HFD2_k127_3704053_3 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 584.0
HFD2_k127_3704053_4 Arginosuccinate synthase K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 502.0
HFD2_k127_3704053_5 HpcH/HpaI aldolase/citrate lyase family K01644 - 4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 492.0
HFD2_k127_3704053_6 argininosuccinate lyase K01755 - 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 369.0
HFD2_k127_3704053_7 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005855 352.0
HFD2_k127_3704053_8 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 327.0
HFD2_k127_3704053_9 mRNA catabolic process K06950,K09163 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006302 263.0
HFD2_k127_3712816_0 Belongs to the aldehyde dehydrogenase family K00128,K00138 - 1.2.1.3 3.524e-209 661.0
HFD2_k127_3712816_1 Phosphohydrolase-associated domain K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 389.0
HFD2_k127_3712816_10 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000001131 125.0
HFD2_k127_3712816_11 transposition, DNA-mediated K02342 - 2.7.7.7 0.00000000000000000000009436 110.0
HFD2_k127_3712816_12 Cytochrome c K00406,K08906 - - 0.00000000000001554 81.0
HFD2_k127_3712816_2 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 359.0
HFD2_k127_3712816_3 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009901 327.0
HFD2_k127_3712816_4 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007057 335.0
HFD2_k127_3712816_5 amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 291.0
HFD2_k127_3712816_6 COGs COG2912 conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001922 251.0
HFD2_k127_3712816_7 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.00000000000000000000000000000000000000000000000000001032 198.0
HFD2_k127_3712816_8 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000002433 170.0
HFD2_k127_3712816_9 COG0604 NADPH quinone reductase and related Zn-dependent - - - 0.000000000000000000000000000000000000009822 169.0
HFD2_k127_3741971_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003357 375.0
HFD2_k127_3741971_1 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000519 306.0
HFD2_k127_3741971_2 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009272 295.0
HFD2_k127_3741971_3 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000003314 228.0
HFD2_k127_3741971_4 Belongs to the CDS family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.00000000000000000000000000000000000000003791 170.0
HFD2_k127_3741971_5 Cytochrome oxidase complex assembly protein 1 - - - 0.00001307 58.0
HFD2_k127_3741971_6 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0004585 44.0
HFD2_k127_3749860_0 Amidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007177 471.0
HFD2_k127_3749860_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 452.0
HFD2_k127_3749860_2 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287,K18589 - 1.5.1.3 0.000000000000000000000000000000000000000000000000007533 184.0
HFD2_k127_3749860_3 major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000001509 183.0
HFD2_k127_3786676_0 beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000001703 215.0
HFD2_k127_3786676_1 - - - - 0.0000000000000000000000000000000000000000000000000002127 198.0
HFD2_k127_3786676_2 ATP synthesis coupled electron transport K00342,K00343,K05568 - 1.6.5.3 0.00000000000000000000000000000000000000000002433 170.0
HFD2_k127_3786676_3 PFAM von Willebrand factor type A - - - 0.000000000000000000000000000000000000005189 165.0
HFD2_k127_3786676_4 DNA-templated transcription, initiation - - - 0.00000000000000000000000000002963 123.0
HFD2_k127_3786676_5 UDP-N-acetylglucosamine-peptide N-acetylglucosaminyltransferase. Source PGD - - - 0.00000000000000000000000003021 124.0
HFD2_k127_3786676_7 Carboxypeptidase regulatory-like domain - - - 0.000007694 59.0
HFD2_k127_3786676_8 Mut7-C RNAse domain K09122 - - 0.000601 43.0
HFD2_k127_3805212_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1327.0
HFD2_k127_3805212_1 response to heat K03694,K03695 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0 1071.0
HFD2_k127_3805212_10 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000000000000006651 193.0
HFD2_k127_3805212_11 Peptidase C26 K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000005734 196.0
HFD2_k127_3805212_12 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000003884 197.0
HFD2_k127_3805212_13 ribose 5-phosphate isomerase B K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000003197 179.0
HFD2_k127_3805212_14 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000005837 180.0
HFD2_k127_3805212_15 Protein of unknown function (DUF3500) - - - 0.0000000000000000000000000000000000000000000001504 186.0
HFD2_k127_3805212_17 PFAM Integral membrane protein DUF92 - GO:0005575,GO:0016020 - 0.000000000000000000000000000000000006371 157.0
HFD2_k127_3805212_18 Amidohydrolase family - - - 0.00000000000000000000000000001166 136.0
HFD2_k127_3805212_19 Alpha/beta hydrolase family - - - 0.000000000000000000000001413 114.0
HFD2_k127_3805212_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008168 496.0
HFD2_k127_3805212_20 lipolytic protein G-D-S-L family - - - 0.000000000000000000000008404 114.0
HFD2_k127_3805212_21 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - 0.0000000000000000000001146 104.0
HFD2_k127_3805212_22 UbiA prenyltransferase family K12501 - 2.5.1.117 0.000000000000000000194 104.0
HFD2_k127_3805212_23 PFAM Organic solvent tolerance protein K04744 - - 0.000000000000000005117 97.0
HFD2_k127_3805212_24 PFAM glycosyl transferase family 39 - - - 0.0000000000000006542 93.0
HFD2_k127_3805212_25 Phosphoserine phosphatase - - - 0.00000000000001725 87.0
HFD2_k127_3805212_26 integral membrane protein - - - 0.000008277 56.0
HFD2_k127_3805212_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003496 466.0
HFD2_k127_3805212_4 Belongs to the Glu Leu Phe Val dehydrogenases family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005114 460.0
HFD2_k127_3805212_5 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008484 458.0
HFD2_k127_3805212_6 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005115 389.0
HFD2_k127_3805212_7 Voltage gated chloride channel K03281 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 367.0
HFD2_k127_3805212_8 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 331.0
HFD2_k127_3805212_9 Polysaccharide biosynthesis protein K15891 - 1.1.1.354 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001008 296.0
HFD2_k127_3823687_0 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 325.0
HFD2_k127_3823687_1 Ferredoxin - - - 0.00000000000000000000000000000000000002552 155.0
HFD2_k127_3823687_2 3-isopropylmalate dehydrogenase activity K00030 - 1.1.1.41 0.000000000000000009299 84.0
HFD2_k127_3823687_3 Belongs to the UPF0235 family K09131 - - 0.000000000002463 75.0
HFD2_k127_3823687_4 - - - - 0.000003085 57.0
HFD2_k127_3830351_0 Predicted membrane protein (DUF2157) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008366 397.0
HFD2_k127_3830351_1 PFAM Electron transfer flavoprotein alpha beta-subunit K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 392.0
HFD2_k127_3830351_10 DoxX - - - 0.000000000000000000000000000000000000000000004522 170.0
HFD2_k127_3830351_11 Lamin Tail Domain - - - 0.000000000000000000000000000000000005435 159.0
HFD2_k127_3830351_12 COG2931 RTX toxins and related Ca2 -binding proteins K01406,K07004 - 3.4.24.40 0.0000000000000000000000000000000007895 152.0
HFD2_k127_3830351_13 - - - - 0.000000000000000000000000000000001332 148.0
HFD2_k127_3830351_15 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K03594 - 1.16.3.1 0.00000000000000000000000008261 119.0
HFD2_k127_3830351_16 - - - - 0.0000000000000000000000009509 109.0
HFD2_k127_3830351_17 IMP dehydrogenase activity - GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0009628,GO:0016020,GO:0030312,GO:0035821,GO:0036293,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052564,GO:0052572,GO:0070482,GO:0071944,GO:0075136 - 0.00000000000000000000006807 105.0
HFD2_k127_3830351_18 translation initiation inhibitor, yjgF family - - - 0.0000000000000000000002882 101.0
HFD2_k127_3830351_19 Periplasmic copper-binding protein (NosD) - - - 0.000000000000000000006365 105.0
HFD2_k127_3830351_2 electron transfer activity K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 389.0
HFD2_k127_3830351_20 phosphorelay signal transduction system - - - 0.000000000000000000017 98.0
HFD2_k127_3830351_21 electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 0.00000000000000001106 83.0
HFD2_k127_3830351_22 SnoaL-like domain - - - 0.0000002722 58.0
HFD2_k127_3830351_3 beta' subunit K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 297.0
HFD2_k127_3830351_4 ribonuclease BN K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001196 275.0
HFD2_k127_3830351_5 Protein of unknown function (DUF1579) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001937 238.0
HFD2_k127_3830351_6 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000002397 257.0
HFD2_k127_3830351_7 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000001909 220.0
HFD2_k127_3830351_8 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000000001181 197.0
HFD2_k127_3830351_9 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000379 188.0
HFD2_k127_384461_0 Mur ligase family, catalytic domain K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000296 464.0
HFD2_k127_384461_1 lipid A export permease ATP-binding protein MsbA K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 453.0
HFD2_k127_384461_2 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000005001 251.0
HFD2_k127_384461_3 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000008121 226.0
HFD2_k127_384461_4 tRNA-splicing ligase RtcB - - - 0.00000000000000000000000000000000000000000000000000002294 214.0
HFD2_k127_384461_6 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.000000000001081 73.0
HFD2_k127_384461_7 OmpW family K07275 - - 0.00000001169 64.0
HFD2_k127_384461_8 HPr Serine kinase C-terminal domain - - - 0.0009062 51.0
HFD2_k127_3848058_0 Bacterial DNA polymerase III alpha subunit K02337,K14162 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 2e-299 971.0
HFD2_k127_3848058_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 3.023e-204 668.0
HFD2_k127_3848058_10 Capsular exopolysaccharide family - - - 0.000000000000000000000000000001584 136.0
HFD2_k127_3848058_11 antitermination protein NusG K05785 - - 0.000000000000000000000000000005977 126.0
HFD2_k127_3848058_12 - - - - 0.00000000005917 69.0
HFD2_k127_3848058_13 Acid phosphatase homologues - - - 0.000000004454 69.0
HFD2_k127_3848058_2 Electron transfer flavoprotein-ubiquinone K00311 - 1.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 456.0
HFD2_k127_3848058_3 protoporphyrinogen oxidase activity K00231,K14266 - 1.14.19.9,1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 411.0
HFD2_k127_3848058_4 PFAM DNA methylase N-4 N-6 domain protein K00571 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005087 314.0
HFD2_k127_3848058_5 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000009972 276.0
HFD2_k127_3848058_6 impB/mucB/samB family K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000001591 254.0
HFD2_k127_3848058_7 Lipopolysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000002986 212.0
HFD2_k127_3848058_8 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 0.0000000000000000000000000000000000000000000000000001199 199.0
HFD2_k127_3848058_9 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01991 - - 0.00000000000000000000000000000000000001388 153.0
HFD2_k127_3848275_0 Amylo-alpha-1,6-glucosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 611.0
HFD2_k127_3848275_1 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000000000002592 203.0
HFD2_k127_3848275_2 lactoylglutathione lyase activity K00941,K01724,K01759,K07032,K08234 - 2.7.1.49,2.7.4.7,4.2.1.96,4.4.1.5 0.000000000000000000000001949 108.0
HFD2_k127_3848275_3 Putative zinc-finger - - - 0.0000237 54.0
HFD2_k127_3848275_4 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0003058 49.0
HFD2_k127_3869405_0 ATP dependent DNA ligase C terminal region K01971 - 6.5.1.1 2.647e-258 821.0
HFD2_k127_3869405_1 Responsible for synthesis of pseudouridine from uracil K06177,K06180 - 5.4.99.23,5.4.99.28,5.4.99.29 0.00000000000000000000000000000007082 130.0
HFD2_k127_3886735_0 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005702 619.0
HFD2_k127_3886735_1 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004305 349.0
HFD2_k127_3886735_2 Glycosyltransferase like family 2 K10012 - 2.4.2.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 349.0
HFD2_k127_3886735_3 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000002326 244.0
HFD2_k127_3886735_4 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000000001298 196.0
HFD2_k127_3886735_5 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000000000000000000001266 197.0
HFD2_k127_3886735_6 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein - - - 0.000000000000000009833 98.0
HFD2_k127_3886735_7 - - - - 0.0000000000000001616 86.0
HFD2_k127_3886735_8 domain, Protein - - - 0.00000006278 64.0
HFD2_k127_3886735_9 TPR repeat - - - 0.0001491 49.0
HFD2_k127_3889626_0 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000008735 229.0
HFD2_k127_3889626_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000001735 175.0
HFD2_k127_3889626_2 phosphorelay signal transduction system - - - 0.0000000000000000000001453 107.0
HFD2_k127_3889626_3 YacP-like NYN domain K06962 - - 0.00001046 53.0
HFD2_k127_3896713_0 HI0933-like protein K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 409.0
HFD2_k127_3896713_1 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 328.0
HFD2_k127_3896713_2 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.000000000000000000000000000000000000000000000000001235 187.0
HFD2_k127_3896713_3 Methyltransferase domain - - - 0.00000000000000000000000000008978 126.0
HFD2_k127_3896713_4 ThiF family K21029,K21147 - 2.7.7.80,2.8.1.11 0.000000000000001122 87.0
HFD2_k127_3896713_5 4-amino-4-deoxy-L-arabinose transferase activity K14340 - - 0.000000000000637 81.0
HFD2_k127_390109_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688,K18786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.321 0.0 1942.0
HFD2_k127_390109_1 Predicted membrane protein (DUF2339) - - - 0.000000000000000000000000000000000000000000000009509 191.0
HFD2_k127_390109_2 Iodothyronine deiodinase - - - 0.00000000000000000000000000001525 122.0
HFD2_k127_390109_3 Protein of unknown function (DUF3999) - - - 0.000000000000000000000000003353 130.0
HFD2_k127_390109_5 - - - - 0.00000000000000000000001592 103.0
HFD2_k127_390109_6 multi-organism process K03195 - - 0.00000004399 63.0
HFD2_k127_3904393_0 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 322.0
HFD2_k127_3904393_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 327.0
HFD2_k127_3904393_2 Belongs to the KdsA family K01627 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008676,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016043,GO:0016051,GO:0016053,GO:0016740,GO:0016765,GO:0019294,GO:0019752,GO:0022607,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046394,GO:0046400,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004788 313.0
HFD2_k127_3904393_3 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase K01627,K03270 - 2.5.1.55,3.1.3.45 0.000000000000000000000000000000000000000000008672 169.0
HFD2_k127_3904393_4 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.000000000000000000000000000000000000000005726 169.0
HFD2_k127_3904393_5 heat shock protein binding - - - 0.0000000000000000003553 98.0
HFD2_k127_3904393_6 Lipopolysaccharide assembly protein A domain K08992 - - 0.0000001064 58.0
HFD2_k127_3919369_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 2.29e-294 938.0
HFD2_k127_3919369_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 1.554e-202 668.0
HFD2_k127_3931393_0 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 2.994e-256 808.0
HFD2_k127_3931393_1 Alpha-amylase domain K05343 - 3.2.1.1,5.4.99.16 3.184e-218 696.0
HFD2_k127_3931393_2 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 601.0
HFD2_k127_3931393_3 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000000000000000000000000000000000000000000000000000000000000008189 257.0
HFD2_k127_3931393_4 - - - - 0.000000004214 63.0
HFD2_k127_3946869_0 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004737 439.0
HFD2_k127_3946869_1 cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006245 432.0
HFD2_k127_3946869_2 PFAM EAL domain - - - 0.000000000000000000000000000000000000000000000004919 192.0
HFD2_k127_3946869_3 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000114 185.0
HFD2_k127_3946869_4 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.000000000000000000000000000002496 131.0
HFD2_k127_3946869_5 response regulator - - - 0.0000000000000000000000000007294 126.0
HFD2_k127_3946869_6 Two component transcriptional regulator, winged helix family K07658 - - 0.00000000000000000000004556 111.0
HFD2_k127_3946869_8 Histidine kinase - - - 0.000002045 58.0
HFD2_k127_3946869_9 PilZ domain - - - 0.0001077 53.0
HFD2_k127_3950280_0 Utp--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008849 379.0
HFD2_k127_3950280_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 306.0
HFD2_k127_3950280_2 methyltransferase activity - - - 0.00000000000000000000000000000000000005225 161.0
HFD2_k127_3950280_3 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000009932 118.0
HFD2_k127_3950280_4 Regulatory protein, FmdB - - - 0.00000000000000001129 88.0
HFD2_k127_3956097_0 Berberine and berberine like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000509 459.0
HFD2_k127_3956097_1 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 360.0
HFD2_k127_397_0 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 523.0
HFD2_k127_397_1 nuclear chromosome segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 436.0
HFD2_k127_397_2 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007938 329.0
HFD2_k127_397_3 COG0577 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 295.0
HFD2_k127_397_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000003765 243.0
HFD2_k127_397_5 outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000003511 225.0
HFD2_k127_397_6 Yip1 domain - - - 0.0004452 52.0
HFD2_k127_4041550_0 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004544 438.0
HFD2_k127_4041550_1 -O-antigen K18814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004062 252.0
HFD2_k127_4041550_2 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.000000000001229 79.0
HFD2_k127_4051041_0 ABC transporter transmembrane region K06147,K18889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006063 385.0
HFD2_k127_4051041_1 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001148 239.0
HFD2_k127_4051041_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000006017 209.0
HFD2_k127_4051041_3 DNA polymerase III, delta subunit, C terminal K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000006174 191.0
HFD2_k127_412054_0 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000006173 111.0
HFD2_k127_412054_2 - - - - 0.00000001044 65.0
HFD2_k127_4123575_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.678e-223 714.0
HFD2_k127_4123575_1 Serine aminopeptidase, S33 K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000007342 234.0
HFD2_k127_4123575_2 PBS lyase - - - 0.0005292 53.0
HFD2_k127_4126732_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 6.4e-322 999.0
HFD2_k127_4126732_1 aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 375.0
HFD2_k127_4126732_2 Raf kinase inhibitor-like protein, YbhB YbcL family K06910 - - 0.0000000000000000000000000000000000000000000000000000000002874 206.0
HFD2_k127_4126732_3 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000002816 205.0
HFD2_k127_4126732_4 4 iron, 4 sulfur cluster binding K05524 GO:0001666,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0009628,GO:0036293,GO:0043207,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0070482,GO:0075136 - 0.0000000000000000000000000000000000000003337 153.0
HFD2_k127_4126732_5 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - 0.000000000000000000000000000000000005319 140.0
HFD2_k127_4126732_6 PFAM Colicin V production protein K03558 - - 0.00000000005757 74.0
HFD2_k127_4126732_7 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000248 61.0
HFD2_k127_4127054_0 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 324.0
HFD2_k127_4127054_1 LD-carboxypeptidase K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000001796 209.0
HFD2_k127_4127054_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000003616 168.0
HFD2_k127_4127054_3 Peptidase M56 - - - 0.000000000000000000000000000009897 136.0
HFD2_k127_4127054_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000275 122.0
HFD2_k127_4127054_5 - - - - 0.00000000000001204 83.0
HFD2_k127_4127054_6 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00006048 55.0
HFD2_k127_4131029_0 Prokaryotic cytochrome b561 - - - 0.0 1136.0
HFD2_k127_4131029_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 576.0
HFD2_k127_4131029_10 4 iron, 4 sulfur cluster binding K05524 GO:0001666,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0009628,GO:0036293,GO:0043207,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0070482,GO:0075136 - 0.0000000000000000000000003228 108.0
HFD2_k127_4131029_11 Dienelactone hydrolase - - - 0.00000000000002497 85.0
HFD2_k127_4131029_13 Predicted Zn-dependent protease (DUF2268) - - - 0.0000001149 64.0
HFD2_k127_4131029_2 Acetyl-CoA hydrolase/transferase N-terminal domain K01067 - 3.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 556.0
HFD2_k127_4131029_3 Aminotransferase class-III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005421 530.0
HFD2_k127_4131029_4 synthetase (ADP forming), alpha K01905,K09181,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009361 518.0
HFD2_k127_4131029_5 DEAD DEAH box helicase domain protein K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 417.0
HFD2_k127_4131029_6 alanine dehydrogenase activity K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006446 326.0
HFD2_k127_4131029_7 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001287 301.0
HFD2_k127_4131029_8 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000174 199.0
HFD2_k127_4131029_9 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000002314 116.0
HFD2_k127_4175505_0 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000004133 240.0
HFD2_k127_4175505_1 ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000001538 231.0
HFD2_k127_4194329_0 FAD linked oxidases, C-terminal domain K00104,K18930 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003226 481.0
HFD2_k127_4194329_1 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.0000000000000000000000000000000000000000000000000002407 194.0
HFD2_k127_4194329_2 FeS cluster assembly scaffold protein NifU K04488 - - 0.00000000000000000000000000000000000211 147.0
HFD2_k127_4194329_3 Sigma-54 interaction domain K11384 - - 0.00000000000000000000002916 104.0
HFD2_k127_4198096_0 Glycosyl hydrolase family 57 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 546.0
HFD2_k127_4198096_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005262 507.0
HFD2_k127_4198096_10 Recombinase zinc beta ribbon domain - - - 0.0000002324 62.0
HFD2_k127_4198096_2 Belongs to the glycosyl hydrolase 57 family K22451 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 481.0
HFD2_k127_4198096_3 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007454 417.0
HFD2_k127_4198096_4 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 433.0
HFD2_k127_4198096_5 Belongs to the glycerate kinase type-1 family K00865 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001074 287.0
HFD2_k127_4198096_6 Glutamine synthetase K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000001142 173.0
HFD2_k127_4198096_7 Member of the two-component regulatory system AtoS AtoC. In the presence of acetoacetate, AtoS AtoC stimulates the expression of the atoDAEB operon, leading to short chain fatty acid catabolism and activation of the poly-(R)-3-hydroxybutyrate (cPHB) biosynthetic pathway. Also induces the operon in response to spermidine. Involved in the regulation of motility and chemotaxis, via transcriptional induction of the flagellar regulon. AtoS is a membrane-associated kinase that phosphorylates and activates AtoC in response to environmental signals K07710 GO:0000155,GO:0000160,GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.13.3 0.000000000000000000000000000000000000000000006299 182.0
HFD2_k127_4198096_8 ubiE/COQ5 methyltransferase family K00570 - 2.1.1.17,2.1.1.71 0.0000000000000000000000000000000000000001367 158.0
HFD2_k127_4198096_9 cheY-homologous receiver domain - - - 0.000000000000000000000000000000006903 134.0
HFD2_k127_4208930_0 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 373.0
HFD2_k127_4208930_1 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000001574 196.0
HFD2_k127_4208930_2 Outer membrane receptor - - - 0.000000000000000000000000000000000000000000000001073 201.0
HFD2_k127_4208930_3 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000007101 165.0
HFD2_k127_4208930_4 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.00000000000000000000000002378 124.0
HFD2_k127_4208930_5 outer membrane protein W K07275 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.0006904 51.0
HFD2_k127_4262311_0 amino acid - - - 2.345e-242 766.0
HFD2_k127_4262311_1 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 3.835e-198 633.0
HFD2_k127_4262311_10 Thioredoxin-like K02199 - - 0.000000000000000000005856 102.0
HFD2_k127_4262311_11 TonB C terminal K03832 - - 0.00000000000000000001865 96.0
HFD2_k127_4262311_12 ADP-ribosylglycohydrolase K05521 - 3.2.2.24 0.00000000000000000006876 90.0
HFD2_k127_4262311_13 NHL repeat - - - 0.0000000000000003247 91.0
HFD2_k127_4262311_14 methyltransferase - - - 0.00000000000007042 81.0
HFD2_k127_4262311_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006675 479.0
HFD2_k127_4262311_3 Threonine synthase K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 436.0
HFD2_k127_4262311_4 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000472 372.0
HFD2_k127_4262311_5 aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000002274 264.0
HFD2_k127_4262311_6 Formyl transferase K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000009063 233.0
HFD2_k127_4262311_7 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000000000003586 198.0
HFD2_k127_4262311_8 N-6 DNA Methylase - - - 0.00000000000000000000000000000000000000000001092 183.0
HFD2_k127_4262311_9 - - - - 0.0000000000000000000000000000000000007499 147.0
HFD2_k127_4286908_0 beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 484.0
HFD2_k127_4286908_1 DegT/DnrJ/EryC1/StrS aminotransferase family K04127 - 5.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 396.0
HFD2_k127_4286908_2 Amino acid permease K03294 - - 0.00000000000000000000000000000000005567 140.0
HFD2_k127_4321125_0 Fumarase C C-terminus K01744 - 4.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008078 378.0
HFD2_k127_4321125_1 PFAM major facilitator superfamily MFS_1 K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004387 351.0
HFD2_k127_4321125_2 SAM (And some other nucleotide) binding motif - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001973 267.0
HFD2_k127_4321125_3 - - - - 0.0000003041 61.0
HFD2_k127_433270_0 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000001951 210.0
HFD2_k127_433270_1 amidohydrolase - - - 0.00000000000000000000000001597 113.0
HFD2_k127_4338331_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003876 556.0
HFD2_k127_4338331_1 His Kinase A (phosphoacceptor) domain K13598 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 543.0
HFD2_k127_4338331_10 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000007338 111.0
HFD2_k127_4338331_11 Fibronectin type 3 domain - - - 0.00000000000000000008174 102.0
HFD2_k127_4338331_12 nuclear chromosome segregation - - - 0.000000000000001968 88.0
HFD2_k127_4338331_13 Domain of unknown function (DUF4390) - - - 0.0000004765 59.0
HFD2_k127_4338331_14 Putative transmembrane protein (PGPGW) - - - 0.000002526 59.0
HFD2_k127_4338331_15 Tetratricopeptide repeat - - - 0.000572 52.0
HFD2_k127_4338331_16 Belongs to the mannose-6-phosphate isomerase type 2 family K00971,K16011 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.7.7.13,5.3.1.8 0.0008813 49.0
HFD2_k127_4338331_2 two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009263 490.0
HFD2_k127_4338331_3 acyl-coa dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004646 431.0
HFD2_k127_4338331_4 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000001974 270.0
HFD2_k127_4338331_5 CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008442 265.0
HFD2_k127_4338331_6 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000004261 222.0
HFD2_k127_4338331_7 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000003248 183.0
HFD2_k127_4338331_8 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000005642 169.0
HFD2_k127_4338331_9 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000003486 169.0
HFD2_k127_4367525_0 acyl-CoA dehydrogenase activity K00249 - 1.3.8.7 0.0 1020.0
HFD2_k127_4367525_1 oxidoreductase K00311,K00313 - 1.5.5.1 5.884e-252 789.0
HFD2_k127_4367525_2 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 596.0
HFD2_k127_4367525_3 spermidine synthase activity K00797 GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006216 389.0
HFD2_k127_4367525_4 Methyltransferase, chemotaxis proteins K00575,K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000002495 236.0
HFD2_k127_4367525_5 Histidine kinase - - - 0.00000000000000000000000000000000000000004716 173.0
HFD2_k127_4367525_6 Gram-negative bacterial TonB protein C-terminal - - - 0.00000000006263 72.0
HFD2_k127_4394586_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 2.222e-197 646.0
HFD2_k127_4394586_1 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000054 595.0
HFD2_k127_4394586_10 Transcriptional regulator - - - 0.0000000000000000000000000000009195 132.0
HFD2_k127_4394586_11 Right handed beta helix region - - - 0.00000000006297 76.0
HFD2_k127_4394586_2 Bacterial Ig-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008748 484.0
HFD2_k127_4394586_3 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004381 439.0
HFD2_k127_4394586_4 Integral membrane protein TerC family K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 392.0
HFD2_k127_4394586_5 Aspartyl protease - - - 0.00000000000000000000000000000000000000000000000000000000949 209.0
HFD2_k127_4394586_6 - - - - 0.000000000000000000000000000000000000000000000002482 194.0
HFD2_k127_4394586_7 B12 binding domain - - - 0.00000000000000000000000000000000000000000002061 182.0
HFD2_k127_4394586_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000002252 141.0
HFD2_k127_4394586_9 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.00000000000000000000000000000004962 138.0
HFD2_k127_4419522_0 Phosphate acyltransferases K05939 - 2.3.1.40,6.2.1.20 1.065e-308 981.0
HFD2_k127_4419522_1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit - - - 5.698e-198 652.0
HFD2_k127_4419522_10 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000003095 154.0
HFD2_k127_4419522_11 AAA domain - - - 0.000000000000000000000000000000000000001009 154.0
HFD2_k127_4419522_12 oxidoreductase activity - - - 0.000000000116 75.0
HFD2_k127_4419522_13 COG3209 Rhs family protein - - - 0.0001065 57.0
HFD2_k127_4419522_2 Prolyl oligopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005503 592.0
HFD2_k127_4419522_3 Proton-conducting membrane transporter K12137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 541.0
HFD2_k127_4419522_4 Proton-conducting membrane transporter K12141 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 515.0
HFD2_k127_4419522_5 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005831 353.0
HFD2_k127_4419522_6 Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 325.0
HFD2_k127_4419522_7 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003922 329.0
HFD2_k127_4419522_8 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 K02806 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004861 269.0
HFD2_k127_4419522_9 hydrogenase 4 membrane K12140 - - 0.0000000000000000000000000000000000000000000000000000001058 202.0
HFD2_k127_4432839_0 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 582.0
HFD2_k127_4432839_1 Biotin and Thiamin Synthesis associated K03150 - 4.1.99.19 0.000000000000000000000000000000000000000000000000000000000000000000000002221 261.0
HFD2_k127_4432839_3 spore germination K07790 - - 0.00000000000000000000000000000000000000000000000001422 200.0
HFD2_k127_4432839_7 Trypsin-like serine protease - - - 0.00008682 53.0
HFD2_k127_4468538_0 PFAM formate-tetrahydrofolate ligase FTHFS K01938 - 6.3.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006318 599.0
HFD2_k127_4468538_1 Pirin C-terminal cupin domain K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004558 516.0
HFD2_k127_4468538_2 GMP synthase (glutamine-hydrolyzing) activity K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 452.0
HFD2_k127_4500559_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 2.08e-279 884.0
HFD2_k127_4500559_1 Ompa motb domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 476.0
HFD2_k127_4500559_2 Large family of predicted nucleotide-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 316.0
HFD2_k127_4500559_3 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000002566 280.0
HFD2_k127_4500559_4 PFAM Proline dehydrogenase K00318 - - 0.0000000000000000000000000000000000000000000000000002042 214.0
HFD2_k127_4500559_5 Two component transcriptional regulator, LuxR family - - - 0.000000000000000000003413 98.0
HFD2_k127_4500559_6 Domain of unknown function DUF11 - - - 0.00001321 49.0
HFD2_k127_4514613_0 Domain of unknown function (DUF5117) - - - 1.528e-217 706.0
HFD2_k127_4514613_1 Domain of unknown function (DUF5117) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000499 642.0
HFD2_k127_4514613_10 - - - - 0.00000001143 61.0
HFD2_k127_4514613_2 Protein of unknown function, DUF255 K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003333 567.0
HFD2_k127_4514613_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007082 451.0
HFD2_k127_4514613_4 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005665 387.0
HFD2_k127_4514613_5 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003745 291.0
HFD2_k127_4514613_6 Peptidase M16 K07263 - - 0.0000000000000000000000000000000000000007123 165.0
HFD2_k127_4514613_7 Smr domain - - - 0.000000000000000000000007022 119.0
HFD2_k127_4514613_8 PFAM peptidase M16 domain protein K07263 - - 0.000000000000000006414 99.0
HFD2_k127_4514613_9 - - - - 0.0000000001411 75.0
HFD2_k127_4524495_0 Amidohydrolase family K06015 - 3.5.1.81 3.567e-245 768.0
HFD2_k127_4524495_1 Acetyl-coenzyme A transporter 1 K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 591.0
HFD2_k127_4524495_10 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000001213 71.0
HFD2_k127_4524495_2 radical SAM domain protein K22318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 432.0
HFD2_k127_4524495_3 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 315.0
HFD2_k127_4524495_4 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000001284 240.0
HFD2_k127_4524495_5 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000001856 191.0
HFD2_k127_4524495_6 Putative ABC exporter - - - 0.000000000000000000000000000000000000000000000005363 194.0
HFD2_k127_4524495_7 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000003922 151.0
HFD2_k127_4524495_8 Phospholipid N-methyltransferase - - - 0.0000000000000000000000000000000000002811 149.0
HFD2_k127_4524495_9 Cupin domain - - - 0.00000000000002892 77.0
HFD2_k127_4638335_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005499 541.0
HFD2_k127_4638335_1 PASTA domain K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007824 446.0
HFD2_k127_4638335_10 Bifunctional protein K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000351 273.0
HFD2_k127_4638335_11 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000002366 262.0
HFD2_k127_4638335_12 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000000000001894 233.0
HFD2_k127_4638335_13 PFAM glycosyl transferase family 9 K02841 - - 0.0000000000000000000000000000000000000000000000000000000000003051 229.0
HFD2_k127_4638335_14 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000001549 208.0
HFD2_k127_4638335_15 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042886,GO:0042887,GO:0043953,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.00000000000000000000000000000000000000000000003719 184.0
HFD2_k127_4638335_16 Type IV pilus biogenesis stability protein PilW - - - 0.0000000000000000000000000000000000000000000763 172.0
HFD2_k127_4638335_17 CoA binding domain K06929 - - 0.000000000000000000000000000000000000002153 164.0
HFD2_k127_4638335_18 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000000001222 139.0
HFD2_k127_4638335_19 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000002152 129.0
HFD2_k127_4638335_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005783 424.0
HFD2_k127_4638335_20 Trm112p-like protein K09791 - - 0.00000000000000002986 85.0
HFD2_k127_4638335_21 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117,K03646 - - 0.00000000002739 74.0
HFD2_k127_4638335_22 - - - - 0.00000000122 63.0
HFD2_k127_4638335_23 Evidence 5 No homology to any previously reported sequences - - - 0.000000002502 64.0
HFD2_k127_4638335_24 Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position K11211 - 2.7.1.166 0.00000001657 67.0
HFD2_k127_4638335_25 Cell division protein FtsQ K03589 - - 0.00000002088 65.0
HFD2_k127_4638335_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007506 411.0
HFD2_k127_4638335_4 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 386.0
HFD2_k127_4638335_5 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008083 355.0
HFD2_k127_4638335_6 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 352.0
HFD2_k127_4638335_7 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004498 312.0
HFD2_k127_4638335_8 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000105 301.0
HFD2_k127_4638335_9 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002297 294.0
HFD2_k127_4644101_0 CHAT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004309 449.0
HFD2_k127_4644101_1 Belongs to the peptidase S8 family K01342 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005576,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030193,GO:0030195,GO:0032101,GO:0032102,GO:0042730,GO:0043170,GO:0044238,GO:0048519,GO:0048583,GO:0048585,GO:0050789,GO:0050818,GO:0050819,GO:0050878,GO:0051239,GO:0051241,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070011,GO:0071704,GO:0080134,GO:0140096,GO:1900046,GO:1900047,GO:1901564,GO:1903034,GO:1903035 3.4.21.62 0.00000000000000000000000000000000000000000000000000000000000000000003117 252.0
HFD2_k127_4644101_2 Glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.0000000000000000000000000000000000000000000000000000000001064 207.0
HFD2_k127_4644101_3 Serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000002324 210.0
HFD2_k127_4644101_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000007151 67.0
HFD2_k127_4658816_0 Multicopper oxidase K08100 - 1.3.3.5 2.937e-236 745.0
HFD2_k127_4658816_1 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008959 516.0
HFD2_k127_4658816_2 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000002534 151.0
HFD2_k127_4658816_3 Sigma-70 region 2 K03088 - - 0.00000000000000000013 94.0
HFD2_k127_4658816_4 Putative zinc-finger - - - 0.0003225 49.0
HFD2_k127_4686013_0 Belongs to the CarA family K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005817 441.0
HFD2_k127_4686013_1 PFAM DAHP synthetase I K03856,K04516 - 2.5.1.54,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008682 402.0
HFD2_k127_4686013_2 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K00015 - 1.1.1.26 0.0000000000000000000000000000000000000000000000000000000000000001572 228.0
HFD2_k127_4686013_3 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000007564 225.0
HFD2_k127_4686013_4 Transcription factor zinc-finger - - - 0.00000000000000000000663 98.0
HFD2_k127_4686013_5 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000002759 73.0
HFD2_k127_4693422_0 4Fe-4S single cluster domain K06937 - - 1.573e-245 773.0
HFD2_k127_4693422_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 3.178e-211 665.0
HFD2_k127_4693422_2 SMART Elongator protein 3 MiaB NifB - - - 5.275e-206 682.0
HFD2_k127_4693422_3 - - - - 0.0000000000000000000002126 104.0
HFD2_k127_4693422_4 Transcriptional regulator - - - 0.0000000000009517 83.0
HFD2_k127_4693422_5 Phosphoglycerate mutase family K08296 - - 0.000002693 57.0
HFD2_k127_4794662_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008544 342.0
HFD2_k127_4794662_1 aerobic electron transport chain K00425,K08738 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000001043 266.0
HFD2_k127_4794662_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000001291 243.0
HFD2_k127_4794662_3 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000002014 198.0
HFD2_k127_4794662_4 Uncharacterized protein conserved in bacteria (DUF2059) K09924 - - 0.00000000001849 72.0
HFD2_k127_4794662_5 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) - - - 0.00007083 53.0
HFD2_k127_4803007_0 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004864 421.0
HFD2_k127_4803007_1 AAA domain K16554 - - 0.00000000000000000000000000000000000000000000000000000000000000000001405 259.0
HFD2_k127_4803007_2 Polysaccharide biosynthesis/export protein - - - 0.00000000007709 66.0
HFD2_k127_4861736_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 555.0
HFD2_k127_4861736_1 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007355 445.0
HFD2_k127_4861736_10 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000158 96.0
HFD2_k127_4861736_11 Forkhead associated domain - - - 0.00000188 61.0
HFD2_k127_4861736_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004416 419.0
HFD2_k127_4861736_3 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 363.0
HFD2_k127_4861736_4 Saccharopine dehydrogenase C-terminal domain K19064 - 1.4.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 304.0
HFD2_k127_4861736_5 (AIR) carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007978 269.0
HFD2_k127_4861736_6 PFAM Neutral alkaline nonlysosomal ceramidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000428 256.0
HFD2_k127_4861736_7 TIGRFAM 40-residue YVTN family beta-propeller repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001031 242.0
HFD2_k127_4861736_8 - - - - 0.00000000000000000000000000000008287 139.0
HFD2_k127_4861736_9 Putative metal-binding motif - - - 0.000000000000000000000000000005478 130.0
HFD2_k127_486380_0 Flotillin K07192 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 376.0
HFD2_k127_486380_1 - - - - 0.000000001065 66.0
HFD2_k127_486380_2 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0009458 48.0
HFD2_k127_4947332_0 benzoyl-CoA reductase K04113 - 1.3.7.8 8.232e-196 624.0
HFD2_k127_4947332_1 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 479.0
HFD2_k127_4947332_2 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 466.0
HFD2_k127_4947332_3 Alcohol dehydrogenase GroES-like domain K07538 - 1.1.1.368 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 374.0
HFD2_k127_4947332_4 O-linked GlcNAc transferase-putative TPR-containing transmembrane protein - - - 0.000000000000000000000000000000006713 145.0
HFD2_k127_4947332_5 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000541 136.0
HFD2_k127_4947332_6 BadF/BadG/BcrA/BcrD ATPase family K04114 - 1.3.7.8 0.0000000000000000161 94.0
HFD2_k127_4985580_0 HELICc2 K03722 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 568.0
HFD2_k127_4985580_1 3'-5' exonuclease K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000175 277.0
HFD2_k127_4985580_2 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000009403 177.0
HFD2_k127_4985580_3 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000004241 83.0
HFD2_k127_4998657_0 ABC 3 transport family K02075,K09816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002729 300.0
HFD2_k127_4998657_1 Belongs to the bacterial solute-binding protein 9 family K02077,K09815,K09818 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002069 269.0
HFD2_k127_4998657_2 Tfp pilus assembly protein FimV - - - 0.00000000000000000000000000000000000001718 161.0
HFD2_k127_4998657_3 Calcineurin-like phosphoesterase superfamily domain K03547 - - 0.00000000000000000000000000000000000154 154.0
HFD2_k127_4998657_4 AAA domain - - - 0.0000000000004823 83.0
HFD2_k127_4998657_5 repeat-containing protein - - - 0.00000007865 65.0
HFD2_k127_5005797_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 409.0
HFD2_k127_5005797_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 398.0
HFD2_k127_5005797_2 HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000009874 226.0
HFD2_k127_5005797_3 Rhomboid family - - - 0.000000000000000000000000000000000000000000001879 173.0
HFD2_k127_5005797_4 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000002823 129.0
HFD2_k127_5005797_5 cell redox homeostasis - - - 0.0000000000000008472 87.0
HFD2_k127_5005797_6 Putative zinc-finger - - - 0.00006017 53.0
HFD2_k127_5019897_0 protein-disulfide reductase activity K04084,K06196 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 424.0
HFD2_k127_5019897_1 Belongs to the peptidase S16 family K01338,K04076,K04770 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004933 358.0
HFD2_k127_5019897_2 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000000109 235.0
HFD2_k127_5019897_3 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000001061 162.0
HFD2_k127_5055921_0 Ribonuclease E/G family K08300,K08301 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008996,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003947 496.0
HFD2_k127_5055921_1 fructose-bisphosphate aldolase activity K01624 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005442 471.0
HFD2_k127_5055921_10 Preprotein translocase, YajC subunit K03210 - - 0.0000000000000000001883 96.0
HFD2_k127_5055921_11 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000009902 96.0
HFD2_k127_5055921_12 TIGRFAM fructose-1,6-bisphosphatase, class II K02446 - 3.1.3.11 0.0000000000006834 81.0
HFD2_k127_5055921_13 shape-determining protein MreD K03571 - - 0.000004944 56.0
HFD2_k127_5055921_14 cell adhesion involved in biofilm formation - - - 0.00004652 55.0
HFD2_k127_5055921_2 Penicillin-binding protein 2 K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 442.0
HFD2_k127_5055921_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 427.0
HFD2_k127_5055921_4 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005831 289.0
HFD2_k127_5055921_5 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000004166 267.0
HFD2_k127_5055921_6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003776 269.0
HFD2_k127_5055921_7 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000002034 155.0
HFD2_k127_5055921_8 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000002222 150.0
HFD2_k127_5055921_9 MgtC SapB transporter K07507 - - 0.00000000000000000000000000000008434 144.0
HFD2_k127_5060859_0 Mycolic acid cyclopropane synthetase - - - 0.00000000000000000000000000000000000000000000000000001665 199.0
HFD2_k127_5060859_1 amidohydrolase - - - 0.00000000000000000002874 101.0
HFD2_k127_5061964_0 Glycine D-amino acid oxidase (deaminating) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 614.0
HFD2_k127_5061964_1 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 455.0
HFD2_k127_5061964_10 Domain of unknown function (DUF4383) - - - 0.00000000000000001206 89.0
HFD2_k127_5061964_11 endonuclease activity - - - 0.000000000000005964 82.0
HFD2_k127_5061964_12 TIGRFAM 40-residue YVTN family beta-propeller repeat protein - - - 0.0000000000001584 83.0
HFD2_k127_5061964_13 endonuclease activity K07451 - - 0.00000000002638 77.0
HFD2_k127_5061964_14 Cro/C1-type HTH DNA-binding domain - - - 0.00000006879 60.0
HFD2_k127_5061964_2 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000463 426.0
HFD2_k127_5061964_3 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006621 414.0
HFD2_k127_5061964_4 aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000539 377.0
HFD2_k127_5061964_5 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 314.0
HFD2_k127_5061964_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 321.0
HFD2_k127_5061964_7 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000184 299.0
HFD2_k127_5061964_8 Bacterioferritin (cytochrome b1) K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000008027 260.0
HFD2_k127_5061964_9 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000009855 104.0
HFD2_k127_506763_0 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 2.617e-221 700.0
HFD2_k127_506763_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11747 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 511.0
HFD2_k127_506763_10 Thrombospondin type 3 repeat - - - 0.000000158 65.0
HFD2_k127_506763_11 Predicted membrane protein (DUF2085) - - - 0.0001212 55.0
HFD2_k127_506763_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 305.0
HFD2_k127_506763_3 Pyridoxal-phosphate dependent enzyme K05396,K17950 - 4.4.1.15,4.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000001816 253.0
HFD2_k127_506763_4 Involved in the tonB-independent uptake of proteins K03641,K10117 - - 0.000000000000000000000000000000000000000003998 179.0
HFD2_k127_506763_5 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.00000000000000000000000000000001613 131.0
HFD2_k127_506763_6 Phospholipid methyltransferase - - - 0.0000000000000000000000000307 117.0
HFD2_k127_506763_7 cell redox homeostasis - - - 0.0000000000000000000000001772 111.0
HFD2_k127_506763_8 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07025 - - 0.00000000000000000000000134 115.0
HFD2_k127_506763_9 - - - - 0.0000000000001896 78.0
HFD2_k127_5082731_0 tRNA binding K04566 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 441.0
HFD2_k127_5082731_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 - 2.3.1.29,2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 412.0
HFD2_k127_5082731_10 methyltransferase - - - 0.00002808 55.0
HFD2_k127_5082731_11 peptidyl-tyrosine sulfation - - - 0.00005935 52.0
HFD2_k127_5082731_2 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 390.0
HFD2_k127_5082731_3 Zinc-binding dehydrogenase K00060 - 1.1.1.103 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003633 391.0
HFD2_k127_5082731_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005311 291.0
HFD2_k127_5082731_5 DNA alkylation repair enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008283 281.0
HFD2_k127_5082731_6 COG0720 6-pyruvoyl-tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000008081 163.0
HFD2_k127_5082731_7 PFAM peptidase - - - 0.000000000000000000000000000006114 130.0
HFD2_k127_5082731_8 Polymer-forming cytoskeletal - - - 0.000000000000000000000000001099 120.0
HFD2_k127_5082731_9 Histidine kinase - - - 0.00000000000000000009587 101.0
HFD2_k127_5097058_0 Alcohol dehydrogenase GroES-like domain K13979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 480.0
HFD2_k127_5097058_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000001237 229.0
HFD2_k127_5097058_2 Involved in the tonB-independent uptake of proteins K03641 - - 0.000000000000000003214 101.0
HFD2_k127_5097058_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000004805 80.0
HFD2_k127_5097058_4 Thrombospondin C-terminal region K04659 GO:0000902,GO:0001501,GO:0001503,GO:0001932,GO:0001934,GO:0001936,GO:0001938,GO:0001968,GO:0002020,GO:0002682,GO:0002684,GO:0002685,GO:0002687,GO:0002688,GO:0002690,GO:0003416,GO:0003417,GO:0003674,GO:0005102,GO:0005178,GO:0005198,GO:0005201,GO:0005488,GO:0005496,GO:0005499,GO:0005509,GO:0005515,GO:0005518,GO:0005539,GO:0005575,GO:0005576,GO:0005604,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005912,GO:0005924,GO:0005927,GO:0006928,GO:0006950,GO:0007155,GO:0007160,GO:0007275,GO:0007399,GO:0007517,GO:0007610,GO:0008150,GO:0008201,GO:0008284,GO:0008289,GO:0009653,GO:0009790,GO:0009887,GO:0009888,GO:0009893,GO:0009987,GO:0010562,GO:0010604,GO:0010941,GO:0012505,GO:0014812,GO:0016043,GO:0016203,GO:0016477,GO:0016525,GO:0016528,GO:0016529,GO:0019220,GO:0019222,GO:0019842,GO:0019899,GO:0021700,GO:0022008,GO:0022603,GO:0022607,GO:0022610,GO:0030030,GO:0030054,GO:0030055,GO:0030154,GO:0030182,GO:0030198,GO:0030334,GO:0030335,GO:0030855,GO:0031012,GO:0031175,GO:0031323,GO:0031325,GO:0031399,GO:0031401,GO:0031589,GO:0031594,GO:0032101,GO:0032103,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0032879,GO:0032989,GO:0032990,GO:0032991,GO:0033554,GO:0033555,GO:0033627,GO:0034103,GO:0034976,GO:0035265,GO:0035989,GO:0036094,GO:0040007,GO:0040011,GO:0040012,GO:0040017,GO:0042127,GO:0042325,GO:0042327,GO:0042981,GO:0043062,GO:0043066,GO:0043067,GO:0043069,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043236,GO:0043237,GO:0043394,GO:0043395,GO:0043931,GO:0043933,GO:0044085,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045202,GO:0045765,GO:0045937,GO:0046872,GO:0048265,GO:0048266,GO:0048468,GO:0048471,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048589,GO:0048646,GO:0048666,GO:0048699,GO:0048705,GO:0048731,GO:0048736,GO:0048799,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048870,GO:0050678,GO:0050679,GO:0050730,GO:0050731,GO:0050789,GO:0050793,GO:0050794,GO:0050839,GO:0050840,GO:0050896,GO:0050920,GO:0050921,GO:0051093,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051216,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051259,GO:0051260,GO:0051270,GO:0051272,GO:0051451,GO:0051674,GO:0051716,GO:0060173,GO:0060231,GO:0060255,GO:0060343,GO:0060346,GO:0060348,GO:0060349,GO:0060350,GO:0060351,GO:0060429,GO:0060538,GO:0060548,GO:0061053,GO:0061061,GO:0061383,GO:0061430,GO:0061448,GO:0062023,GO:0065003,GO:0065007,GO:0070161,GO:0070977,GO:0071603,GO:0071622,GO:0071624,GO:0071695,GO:0071840,GO:0080090,GO:0090022,GO:0090023,GO:0090136,GO:0097159,GO:0097367,GO:0098609,GO:0098868,GO:0120036,GO:0120039,GO:1901342,GO:1901343,GO:1901681,GO:1902622,GO:1902624,GO:2000026,GO:2000145,GO:2000147,GO:2000181 - 0.000001696 62.0
HFD2_k127_5097058_5 peptidyl-tyrosine sulfation - - - 0.0003048 51.0
HFD2_k127_5129591_0 Aconitase C-terminal domain K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 557.0
HFD2_k127_514133_0 response regulator K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 394.0
HFD2_k127_5177286_0 DNA polymerase X family K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009485 568.0
HFD2_k127_5177286_1 4Fe-4S double cluster binding domain K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000007362 241.0
HFD2_k127_5177286_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000001124 243.0
HFD2_k127_5177286_3 conserved protein UCP033563 - - - 0.000000000000000000000000000000000000000006208 171.0
HFD2_k127_5177286_4 Belongs to the peptidase S8 family K13276,K17734 - - 0.0000000000002066 81.0
HFD2_k127_5186709_0 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000028 152.0
HFD2_k127_5186709_1 Belongs to the peptidase M24B family - - - 0.000000000000000000000000000000004958 141.0
HFD2_k127_5213975_0 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 610.0
HFD2_k127_5213975_1 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 300.0
HFD2_k127_5213975_10 Domain of unknown function (DUF4440) - - - 0.000000000000000000001041 109.0
HFD2_k127_5213975_12 - - - - 0.00000000000000001357 97.0
HFD2_k127_5213975_13 Fatty acid desaturase - - - 0.0000005911 59.0
HFD2_k127_5213975_14 Protein of unknown function (DUF1579) - - - 0.0006945 49.0
HFD2_k127_5213975_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007195 306.0
HFD2_k127_5213975_3 PFAM Ribonuclease BN-like family K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009745 290.0
HFD2_k127_5213975_4 Type II restriction enzyme, methylase subunits - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006096 306.0
HFD2_k127_5213975_5 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009956 278.0
HFD2_k127_5213975_6 - - - - 0.0000000000000000000000000000000000000000000000000000006269 205.0
HFD2_k127_5213975_7 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000001863 202.0
HFD2_k127_5213975_8 ECF sigma factor - - - 0.0000000000000000000000000000000000000000004424 177.0
HFD2_k127_5213975_9 - - - - 0.0000000000000000000001488 109.0
HFD2_k127_5217821_0 Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 458.0
HFD2_k127_5217821_1 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.0000000000000000000000000000000000002569 143.0
HFD2_k127_5217821_2 low molecular weight K03741 - 1.20.4.1 0.00000000000000004004 96.0
HFD2_k127_522980_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 461.0
HFD2_k127_522980_1 Threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003891 379.0
HFD2_k127_522980_2 GTPase activity K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003213 287.0
HFD2_k127_522980_3 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002661 281.0
HFD2_k127_522980_4 Oxygen tolerance - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008645 256.0
HFD2_k127_522980_5 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.000000000000000000000000000000000004509 153.0
HFD2_k127_522980_6 tetratricopeptide repeat - - - 0.00000000000000000000000005288 125.0
HFD2_k127_522980_7 - - - - 0.0000000001715 69.0
HFD2_k127_5237245_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 469.0
HFD2_k127_5237245_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007908 426.0
HFD2_k127_5237245_2 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000004063 119.0
HFD2_k127_5257128_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821,K03918,K07250,K13524 - 2.6.1.11,2.6.1.17,2.6.1.19,2.6.1.22,2.6.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 350.0
HFD2_k127_5257128_1 molybdenum ion binding K07140 - - 0.00000000000000000000000000000000000000000000000000000000000000007719 229.0
HFD2_k127_5257128_2 PFAM Class I peptide chain release factor K15034 - - 0.00000000000000000000002415 105.0
HFD2_k127_5264628_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 4.268e-269 840.0
HFD2_k127_5264628_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 1.143e-256 808.0
HFD2_k127_5264628_10 aminopeptidase - - - 0.0000000000000000000000000000000309 148.0
HFD2_k127_5264628_11 - - - - 0.000000000000000000000001334 118.0
HFD2_k127_5264628_12 PFAM AhpC TSA family - - - 0.0000000000001243 75.0
HFD2_k127_5264628_13 - - - - 0.000000000002465 80.0
HFD2_k127_5264628_14 M6 family metalloprotease domain protein - - - 0.000003491 61.0
HFD2_k127_5264628_15 - - - - 0.00001381 59.0
HFD2_k127_5264628_17 Redoxin - - - 0.0002067 52.0
HFD2_k127_5264628_2 hydrolase family 92 - - - 5.842e-221 706.0
HFD2_k127_5264628_3 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 530.0
HFD2_k127_5264628_4 dioxygenase K15777 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0046566,GO:0051213,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 359.0
HFD2_k127_5264628_5 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004636 346.0
HFD2_k127_5264628_6 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 342.0
HFD2_k127_5264628_7 NmrA-like family K19267 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000001166 247.0
HFD2_k127_5264628_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K20444 - - 0.00000000000000000000000000000000000000000000000000000001789 215.0
HFD2_k127_5264628_9 Stigma-specific protein, Stig1 - - - 0.0000000000000000000000000000000000000000006602 183.0
HFD2_k127_5338797_0 Pyridoxal-dependent decarboxylase conserved domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 569.0
HFD2_k127_5338797_1 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.000000000666 63.0
HFD2_k127_53707_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006397 393.0
HFD2_k127_53707_1 Reverse transcriptase-like K03469 - 3.1.26.4 0.0000000000000000000000000000000003266 141.0
HFD2_k127_53707_2 C4-type zinc ribbon domain K07164 - - 0.000000000000003391 85.0
HFD2_k127_53707_3 PilZ domain - - - 0.00001926 51.0
HFD2_k127_5387745_0 Peptidase family M1 domain - - - 2.816e-242 762.0
HFD2_k127_5387745_1 OPT oligopeptide transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000353 541.0
HFD2_k127_5387745_2 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009463 327.0
HFD2_k127_5387745_3 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000006248 218.0
HFD2_k127_5387745_4 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.0000000000000000000000000000000000000000000000000000001251 203.0
HFD2_k127_5387745_5 - - - - 0.0000000001734 74.0
HFD2_k127_5401571_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1498.0
HFD2_k127_5401571_1 Hemerythrin HHE cation binding domain K01534 - 3.6.3.3,3.6.3.5 3.79e-206 660.0
HFD2_k127_5401571_10 Uncharacterized conserved protein (DUF2249) - - - 0.000000000000000000002434 104.0
HFD2_k127_5401571_11 PFAM sodium K14445 - - 0.000000000000000000003889 108.0
HFD2_k127_5401571_12 Belongs to the peptidase S8 family K01337,K01387,K05994,K08604,K14645,K20276 - 3.4.11.10,3.4.21.50,3.4.24.25,3.4.24.3 0.00000000000000000004238 104.0
HFD2_k127_5401571_13 - - - - 0.0000000000002584 73.0
HFD2_k127_5401571_14 - - - - 0.000000000008635 67.0
HFD2_k127_5401571_2 Beta-eliminating lyase K01667 - 4.1.99.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009929 591.0
HFD2_k127_5401571_3 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004057 604.0
HFD2_k127_5401571_4 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008905 592.0
HFD2_k127_5401571_5 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005523 404.0
HFD2_k127_5401571_6 Elongator protein 3, MiaB family, Radical SAM K22227 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 371.0
HFD2_k127_5401571_7 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000007868 209.0
HFD2_k127_5401571_8 Transcriptional regulator, Crp Fnr family - - - 0.0000000000000000000000000000000000000000002812 169.0
HFD2_k127_5401571_9 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000001981 123.0
HFD2_k127_5418008_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004629 416.0
HFD2_k127_5418008_1 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001884 269.0
HFD2_k127_5418008_2 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000001081 203.0
HFD2_k127_5418008_3 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000000006871 158.0
HFD2_k127_5418008_4 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000001097 170.0
HFD2_k127_5418008_5 protein trimerization - - - 0.00001237 55.0
HFD2_k127_5418008_6 Tetratricopeptide repeat - - - 0.000306 53.0
HFD2_k127_5423780_0 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 432.0
HFD2_k127_5423780_1 Tryptophan halogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 409.0
HFD2_k127_5423780_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000005558 233.0
HFD2_k127_5423780_3 DoxX K15977 - - 0.0000000000000000000000000000000000000000002259 171.0
HFD2_k127_5423780_4 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000003631 169.0
HFD2_k127_5423780_5 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000001221 135.0
HFD2_k127_5423780_6 Cytochrome c K17222 - - 0.0000000000000000000141 96.0
HFD2_k127_5423780_7 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.000000005617 64.0
HFD2_k127_5428419_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006502 551.0
HFD2_k127_5428419_1 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004464 536.0
HFD2_k127_5428419_10 citrate CoA-transferase activity K01643 - 2.8.3.10 0.00000000001485 65.0
HFD2_k127_5428419_11 TIGRFAM Caa(3)-type oxidase, subunit IV K02277 - 1.9.3.1 0.00008658 49.0
HFD2_k127_5428419_2 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 512.0
HFD2_k127_5428419_3 Pkd domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 517.0
HFD2_k127_5428419_4 Pkd domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005015 502.0
HFD2_k127_5428419_5 Cytochrome c7 and related cytochrome c K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 307.0
HFD2_k127_5428419_6 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007372 261.0
HFD2_k127_5428419_7 Cytochrome C oxidase subunit II, periplasmic domain K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000005959 250.0
HFD2_k127_5428419_8 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000002669 197.0
HFD2_k127_5428419_9 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000006789 122.0
HFD2_k127_5438303_0 Involved in the tonB-independent uptake of proteins - - - 2.196e-197 644.0
HFD2_k127_5438303_1 phosphorelay signal transduction system K02481,K07713,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 518.0
HFD2_k127_5438303_10 Glycine cleavage H-protein - - - 0.000000000000000000000000000000000000000000000000002245 189.0
HFD2_k127_5438303_11 conserved protein UCP033924 - - - 0.0000000000000000000000000000000000001818 149.0
HFD2_k127_5438303_12 Phosphoglycerate mutase family - - - 0.000000000000000000000000002895 119.0
HFD2_k127_5438303_13 Peptidase family M54 K06974 - - 0.00000000000000000000000008112 114.0
HFD2_k127_5438303_14 Protein of unknown function (DUF421) - - - 0.0000000000000000000001362 101.0
HFD2_k127_5438303_15 PFAM TPR repeat-containing protein - - - 0.0000000000000008737 92.0
HFD2_k127_5438303_16 COG1520 FOG WD40-like repeat - - - 0.00000000000003254 87.0
HFD2_k127_5438303_17 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657 - - 0.00000000004904 66.0
HFD2_k127_5438303_18 heparin binding K04659,K16857 GO:0001501,GO:0001968,GO:0002020,GO:0003416,GO:0003417,GO:0003674,GO:0005198,GO:0005201,GO:0005488,GO:0005496,GO:0005499,GO:0005509,GO:0005515,GO:0005518,GO:0005539,GO:0005575,GO:0005576,GO:0005912,GO:0005924,GO:0005927,GO:0007155,GO:0007275,GO:0007517,GO:0008150,GO:0008201,GO:0008289,GO:0009653,GO:0009887,GO:0009888,GO:0009987,GO:0010941,GO:0016043,GO:0016203,GO:0019842,GO:0019899,GO:0022610,GO:0030054,GO:0030055,GO:0030198,GO:0031012,GO:0032501,GO:0032502,GO:0032991,GO:0033627,GO:0035265,GO:0036094,GO:0040007,GO:0042981,GO:0043062,GO:0043066,GO:0043067,GO:0043069,GO:0043167,GO:0043168,GO:0043169,GO:0043394,GO:0043395,GO:0044421,GO:0044877,GO:0046872,GO:0048513,GO:0048519,GO:0048523,GO:0048589,GO:0048705,GO:0048731,GO:0048736,GO:0048856,GO:0050789,GO:0050794,GO:0051216,GO:0060173,GO:0060348,GO:0060349,GO:0060350,GO:0060351,GO:0060538,GO:0060548,GO:0061061,GO:0061448,GO:0062023,GO:0065007,GO:0070161,GO:0071840,GO:0097159,GO:0097367,GO:0098868,GO:1901681 - 0.00001408 59.0
HFD2_k127_5438303_2 Purple acid Phosphatase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 460.0
HFD2_k127_5438303_3 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 422.0
HFD2_k127_5438303_4 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009529 363.0
HFD2_k127_5438303_5 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 351.0
HFD2_k127_5438303_6 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003916 267.0
HFD2_k127_5438303_7 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002071 256.0
HFD2_k127_5438303_8 peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005823 256.0
HFD2_k127_5438303_9 PFAM methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000005445 211.0
HFD2_k127_5452473_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 6.115e-201 646.0
HFD2_k127_5452473_1 Thiamine biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 324.0
HFD2_k127_5452473_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000004067 141.0
HFD2_k127_5452473_3 Belongs to the sulfur carrier protein TusA family - - - 0.00000000000000069 88.0
HFD2_k127_5457778_0 HlyD family secretion protein - - - 0.0000000000000004036 91.0
HFD2_k127_5457778_1 - - - - 0.00000008425 63.0
HFD2_k127_5480236_0 PFAM Type II secretion system protein E K02652 - - 3.537e-224 707.0
HFD2_k127_5480236_1 PFAM Type II secretion system F domain K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 298.0
HFD2_k127_5480236_2 Pilus assembly protein K02662 - - 0.00000000000004589 83.0
HFD2_k127_5480236_3 PFAM Fimbrial assembly family protein K02663 - - 0.000000016 65.0
HFD2_k127_5480236_4 type IV pilus secretin PilQ K02666 - - 0.00000007811 63.0
HFD2_k127_5486569_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 1.547e-311 976.0
HFD2_k127_5486569_1 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004488 282.0
HFD2_k127_5486569_2 Belongs to the NadC ModD family K00767,K03813 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000004315 268.0
HFD2_k127_5486569_3 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000001067 179.0
HFD2_k127_5486569_4 Low molecular weight phosphatase family K01104 - 3.1.3.48 0.0000000001334 74.0
HFD2_k127_5492481_0 Carbamoyltransferase C-terminus K00612 - - 3.588e-259 812.0
HFD2_k127_5492481_1 CHAT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 355.0
HFD2_k127_5492481_2 - - - - 0.00000002099 67.0
HFD2_k127_5492481_3 - - - - 0.000003837 53.0
HFD2_k127_5492481_4 - - - - 0.00002929 49.0
HFD2_k127_5517204_0 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006551 270.0
HFD2_k127_5517204_1 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000001531 224.0
HFD2_k127_5517204_2 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000004759 189.0
HFD2_k127_5517204_3 - - - - 0.0000005399 62.0
HFD2_k127_5542103_0 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008529 523.0
HFD2_k127_5542103_1 UbiA prenyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001768 291.0
HFD2_k127_5542103_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000005131 220.0
HFD2_k127_5542103_3 Glycosyltransferase like family 2 - - - 0.000000000000000000001141 99.0
HFD2_k127_5543565_0 Beta-eliminating lyase K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002969 424.0
HFD2_k127_5543565_1 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000004877 256.0
HFD2_k127_5543565_2 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000008295 232.0
HFD2_k127_5553686_0 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 6.092e-215 677.0
HFD2_k127_5553686_1 Belongs to the RtcB family K14415 - 6.5.1.3 2.647e-211 666.0
HFD2_k127_5553686_10 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0046167,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901576 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004086 285.0
HFD2_k127_5553686_11 Competence-damaged protein K03742,K03743 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006292 291.0
HFD2_k127_5553686_12 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000003221 259.0
HFD2_k127_5553686_13 Tetratricopeptide repeats - - - 0.00000000000000000000000000000000000000000000000000000000000001549 244.0
HFD2_k127_5553686_14 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000002423 217.0
HFD2_k127_5553686_15 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000002889 207.0
HFD2_k127_5553686_16 pfam php K01104 - 3.1.3.48 0.000000000000000000000000000000000000000000000000000003575 201.0
HFD2_k127_5553686_17 Riboflavin synthase K00793 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 0.00000000000000000000000000000000000000000000000009656 184.0
HFD2_k127_5553686_18 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000002485 173.0
HFD2_k127_5553686_19 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000002216 162.0
HFD2_k127_5553686_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003108 538.0
HFD2_k127_5553686_20 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000000002372 149.0
HFD2_k127_5553686_21 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000166 150.0
HFD2_k127_5553686_22 PFAM Lytic transglycosylase catalytic K08309 - - 0.000000000000000000000000000000001824 149.0
HFD2_k127_5553686_23 Acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000007022 140.0
HFD2_k127_5553686_24 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000332 130.0
HFD2_k127_5553686_25 Archease protein family (MTH1598/TM1083) - - - 0.0000000000000000000000000002584 119.0
HFD2_k127_5553686_26 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0008150,GO:0040007 - 0.00000000000000000000952 99.0
HFD2_k127_5553686_27 Belongs to the UPF0109 family K06960 - - 0.000000000000000007589 98.0
HFD2_k127_5553686_28 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000002071 81.0
HFD2_k127_5553686_29 TIGRFAM TIGR03032 family protein - - - 0.0000000000003389 81.0
HFD2_k127_5553686_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004753 473.0
HFD2_k127_5553686_30 helix_turn_helix, arabinose operon control protein - - - 0.0000000000004003 79.0
HFD2_k127_5553686_31 periplasmic or secreted lipoprotein K04065 - - 0.000000001686 68.0
HFD2_k127_5553686_4 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 456.0
HFD2_k127_5553686_5 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 428.0
HFD2_k127_5553686_6 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002887 383.0
HFD2_k127_5553686_7 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008271 383.0
HFD2_k127_5553686_8 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 336.0
HFD2_k127_5553686_9 SRP-dependent cotranslational protein targeting to membrane K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001805 297.0
HFD2_k127_5557482_0 cellulose binding - - - 0.0 1281.0
HFD2_k127_5557482_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.24e-270 868.0
HFD2_k127_5557482_10 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000002379 74.0
HFD2_k127_5557482_11 acyl carrier protein K02078 - - 0.0000000007546 63.0
HFD2_k127_5557482_12 Alkyl hydroperoxide reductase K03386 - 1.11.1.15 0.000000001292 61.0
HFD2_k127_5557482_13 peptidylprolyl isomerase K01802 - 5.2.1.8 0.00002398 57.0
HFD2_k127_5557482_2 PFAM Peptidase M20 K12941 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 543.0
HFD2_k127_5557482_3 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000601 430.0
HFD2_k127_5557482_4 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005673 371.0
HFD2_k127_5557482_5 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002952 273.0
HFD2_k127_5557482_6 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000001752 174.0
HFD2_k127_5557482_7 - - - - 0.00000000000000000000000000003091 124.0
HFD2_k127_5557482_8 Hfq protein - - - 0.000000000000000000000000000165 117.0
HFD2_k127_5557482_9 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K07533 - 5.2.1.8 0.0000000000000000000005788 111.0
HFD2_k127_5557719_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K13598 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000125 243.0
HFD2_k127_5557719_1 Protein of unknown function, DUF255 K06888 - - 0.000000000000000000000000000000000000000000000000003417 199.0
HFD2_k127_5557719_2 lysine biosynthesis protein LysW K05826 - - 0.0002145 49.0
HFD2_k127_5574175_0 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000003923 169.0
HFD2_k127_5574175_1 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.0000000000000000000000000000000001965 134.0
HFD2_k127_5574175_2 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000002556 110.0
HFD2_k127_5574175_3 BolA-like protein - - - 0.00000000000001395 85.0
HFD2_k127_5574175_4 Tetratricopeptide TPR_2 repeat protein - - - 0.0008041 47.0
HFD2_k127_5633979_0 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003594 425.0
HFD2_k127_5633979_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000882 405.0
HFD2_k127_5633979_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000001354 265.0
HFD2_k127_5633979_3 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000003502 240.0
HFD2_k127_5633979_4 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000000001537 189.0
HFD2_k127_5633979_5 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.0000000000000000000000000000000000006383 150.0
HFD2_k127_5640760_0 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004625 557.0
HFD2_k127_5640760_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003762 394.0
HFD2_k127_5640760_2 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 353.0
HFD2_k127_5640760_3 Isochorismatase family K08281 - 3.5.1.19 0.00000000000000000000000000000000000000000000000003446 201.0
HFD2_k127_5640760_4 fatty acid desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000001313 168.0
HFD2_k127_5640760_5 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000003043 98.0
HFD2_k127_5640760_6 Peptidase dimerisation domain - - - 0.000000000003407 78.0
HFD2_k127_5665474_0 pfam abc K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000235 288.0
HFD2_k127_5665474_1 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008724 256.0
HFD2_k127_5665474_2 Phosphoribosyl transferase domain K07100 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000002773 129.0
HFD2_k127_5668755_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 1.918e-236 760.0
HFD2_k127_5668755_1 Amino acid permease - - - 6.375e-215 688.0
HFD2_k127_5668755_2 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008649 368.0
HFD2_k127_5668755_3 Response receiver-modulated cyclic diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006458 338.0
HFD2_k127_5668755_4 Domain of unknown function (DUF3488) - - - 0.000000000000000000000000000000000000000000000000000000000000004482 247.0
HFD2_k127_5668755_5 PFAM response regulator receiver K02483,K07667 - - 0.000000000000000000000000000000000000000000000000000000004 215.0
HFD2_k127_5668755_6 Histidine kinase K07646 - 2.7.13.3 0.00000000000000000000000000000000000000003387 177.0
HFD2_k127_5668755_7 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.0000000000000000002681 103.0
HFD2_k127_5668755_8 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity K03429 - 2.4.1.315 0.00000000000000001398 86.0
HFD2_k127_5672770_0 ASPIC and UnbV - - - 4.96e-200 674.0
HFD2_k127_5672770_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003507 272.0
HFD2_k127_5672770_2 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000002053 168.0
HFD2_k127_5750822_0 COG1228 Imidazolonepropionase and related K01443 - 3.5.1.25 1.099e-198 661.0
HFD2_k127_5750822_1 PFAM Sodium sulphate symporter K14445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 327.0
HFD2_k127_5750822_10 CAAX protease self-immunity K07052 - - 0.000001031 59.0
HFD2_k127_5750822_2 imidazolonepropionase activity K01443 - 3.5.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 301.0
HFD2_k127_5750822_3 Glutathione S-transferase, C-terminal domain - - - 0.00000000000000000000000000000000000004335 164.0
HFD2_k127_5750822_4 protein conserved in bacteria K09931 - - 0.000000000000000000000000000000008576 146.0
HFD2_k127_5750822_5 ABC transporter K15738 - - 0.00000000000000000000000000000006195 137.0
HFD2_k127_5750822_6 - - - - 0.000000000000000000000000000003135 134.0
HFD2_k127_5750822_7 Hydrolase, TatD family K03424 - - 0.00000000000000000007816 102.0
HFD2_k127_5750822_8 MATE efflux family protein - - - 0.0000000000004723 81.0
HFD2_k127_5750822_9 Trypsin-like serine protease - - - 0.000000005761 66.0
HFD2_k127_5793610_0 Acts as a magnesium transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 402.0
HFD2_k127_5793610_1 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000002573 197.0
HFD2_k127_5793610_2 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.0001335 55.0
HFD2_k127_5798863_0 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001019 291.0
HFD2_k127_5798863_1 Transporter associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000001435 226.0
HFD2_k127_5838216_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006208 357.0
HFD2_k127_5838216_1 GTP binding K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001381 265.0
HFD2_k127_5838216_2 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000001784 233.0
HFD2_k127_5838216_3 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.00000000000000000000000000000000000000000000000000003441 203.0
HFD2_k127_5838216_4 bacterial (prokaryotic) histone like domain K03530 - - 0.0000000000000000000000001237 119.0
HFD2_k127_5838216_5 solute binding protein K02035 - - 0.0000002041 63.0
HFD2_k127_5840955_0 histidine kinase A domain protein K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 361.0
HFD2_k127_5840955_1 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000008656 172.0
HFD2_k127_5853361_0 Peptidase, M61 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003139 569.0
HFD2_k127_5853361_1 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003248 316.0
HFD2_k127_5858621_0 4Fe-4S single cluster domain K06871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002235 264.0
HFD2_k127_5858621_1 ATP-grasp domain - - - 0.00000006083 65.0
HFD2_k127_5858621_2 ligase activity - - - 0.00000008793 66.0
HFD2_k127_5863388_0 [glutamate-ammonia-ligase] adenylyltransferase activity K00982 GO:0000166,GO:0000287,GO:0000820,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0019222,GO:0019752,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0033238,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.42,2.7.7.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000677 473.0
HFD2_k127_5863388_1 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 291.0
HFD2_k127_5863388_2 cyclic nucleotide-binding - - - 0.00000000000000003004 89.0
HFD2_k127_5878717_0 copper-translocating P-type ATPase K17686 - 3.6.3.54 8.169e-213 672.0
HFD2_k127_5878717_1 L,D-transpeptidase catalytic domain K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001564 289.0
HFD2_k127_5878717_2 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000007835 209.0
HFD2_k127_5878717_3 EamA-like transporter family - - - 0.000000000002561 78.0
HFD2_k127_5881722_0 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 361.0
HFD2_k127_5881722_1 Alcohol dehydrogenase GroES-like domain K00001 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006677 291.0
HFD2_k127_5881722_2 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000000000000000000000006671 113.0
HFD2_k127_5881722_3 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.000000000000000000000297 104.0
HFD2_k127_5881722_4 Glycosyl transferase family 41 - - - 0.0000001184 64.0
HFD2_k127_589332_0 Sortilin, neurotensin receptor 3, - - - 0.0 1120.0
HFD2_k127_589332_1 Glycosyl hydrolases family 15 - - - 6.538e-254 814.0
HFD2_k127_589332_2 Repeats in polycystic kidney disease 1 (PKD1) and other proteins K02674,K07004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 338.0
HFD2_k127_589332_3 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001654 275.0
HFD2_k127_589332_4 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000000000000000000000000000002729 227.0
HFD2_k127_589332_5 Zn peptidase - - - 0.0000000000000000000000000000000000000000001077 175.0
HFD2_k127_589332_6 Methyltransferase domain - - - 0.0000000000000000008557 101.0
HFD2_k127_589332_7 Concanavalin A-like lectin/glucanases superfamily - - - 0.0000000000006853 83.0
HFD2_k127_589332_8 lysyltransferase activity K07027 - - 0.00000004294 66.0
HFD2_k127_5894521_0 SMART Phospholipid glycerol acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 523.0
HFD2_k127_5894521_1 Linear amide C-N hydrolases, choloylglycine hydrolase family K01442 - 3.5.1.24 0.000000000000000000000000000000000000000000001088 179.0
HFD2_k127_5894521_2 Transport and Golgi organisation 2 K01755 - 4.3.2.1 0.0000000000000000000005141 97.0
HFD2_k127_5894521_3 DinB superfamily - - - 0.0000000000000000001869 102.0
HFD2_k127_5894521_4 transposition, DNA-mediated K02342 - 2.7.7.7 0.00000000000000001216 95.0
HFD2_k127_5896408_0 Insulinase (Peptidase family M16) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 556.0
HFD2_k127_5896408_1 Peptidase M16 inactive domain K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 573.0
HFD2_k127_5896408_2 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.000000000000000000000000000000000000000000000000000000000000006348 244.0
HFD2_k127_5896408_3 PFAM Adenosine AMP deaminase K01488,K18286 - 3.5.4.4,3.5.4.40 0.0000000000000000000000000000000000000000000000000002303 198.0
HFD2_k127_5896408_4 cellulase activity - - - 0.0000000000000000000000000000000000000000000000005152 203.0
HFD2_k127_5896408_5 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.00001702 57.0
HFD2_k127_5904639_0 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000000008753 119.0
HFD2_k127_5904639_1 Prokaryotic N-terminal methylation motif K02456 - - 0.00000000000000000000000006583 115.0
HFD2_k127_5904639_2 general secretion pathway protein G K02456 - - 0.0000000004379 68.0
HFD2_k127_5904639_3 -O-antigen K07234 - - 0.000008035 57.0
HFD2_k127_5904639_4 IMG reference gene - - - 0.00006187 52.0
HFD2_k127_5919415_0 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 439.0
HFD2_k127_5919415_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006494 262.0
HFD2_k127_5919415_2 PFAM glycosyl transferase family 39 K14340 - - 0.00000000000000000000000000000000000000000000000000000000000000002538 248.0
HFD2_k127_5919415_3 Related to alanyl-tRNA synthetase HxxxH domain K01872,K07050 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000001093 231.0
HFD2_k127_5919415_4 Tetratricopeptide repeat - - - 0.000000000000004172 83.0
HFD2_k127_5972919_0 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 392.0
HFD2_k127_5972919_1 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000382 336.0
HFD2_k127_5972919_2 peroxiredoxin activity - - - 0.000000000000000000000000000000000000000000000001205 186.0
HFD2_k127_5972919_3 Domain of unknown function (DUF309) K09763 - - 0.00000000000002712 81.0
HFD2_k127_5972919_4 deoxyhypusine monooxygenase activity - - - 0.0006618 52.0
HFD2_k127_6005389_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 485.0
HFD2_k127_6005389_1 Isocitrate isopropylmalate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 327.0
HFD2_k127_6005389_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000236 258.0
HFD2_k127_6005389_3 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000587 246.0
HFD2_k127_6005389_4 Base excision DNA repair protein K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000004722 184.0
HFD2_k127_6005389_5 general secretion pathway protein G K02456 - - 0.000006351 53.0
HFD2_k127_6007085_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 7.531e-247 774.0
HFD2_k127_6007085_1 DNA Topoisomerase IV K02469 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 448.0
HFD2_k127_6007085_2 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004197 417.0
HFD2_k127_6007085_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 318.0
HFD2_k127_6007085_4 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0044237,GO:0071704,GO:1901135 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005082 302.0
HFD2_k127_6007085_5 Protein of unknown function (DUF4242) - - - 0.00000000000000000007589 103.0
HFD2_k127_6010351_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 2.357e-236 751.0
HFD2_k127_6010351_1 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009234 388.0
HFD2_k127_6010351_10 Domain of unknown function (DUF4162) K01990 - - 0.0000000003625 66.0
HFD2_k127_6010351_11 - - - - 0.000000009501 66.0
HFD2_k127_6010351_12 - - - - 0.00000001172 63.0
HFD2_k127_6010351_13 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.0000001901 54.0
HFD2_k127_6010351_14 PFAM Abortive infection protein K07052 - - 0.000003952 58.0
HFD2_k127_6010351_2 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 358.0
HFD2_k127_6010351_3 peptidase M48, Ste24p - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005428 300.0
HFD2_k127_6010351_4 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000002269 236.0
HFD2_k127_6010351_5 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000002192 226.0
HFD2_k127_6010351_6 ABC transporter - - - 0.0000000000000000000000000000000000000000000000003268 184.0
HFD2_k127_6010351_7 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.000000000000000000000000000000000000000000297 163.0
HFD2_k127_6010351_8 OsmC-like protein - - - 0.0000000000000000000000000005045 130.0
HFD2_k127_6010351_9 Transport permease protein K01992 - - 0.00000000000000000000000007507 124.0
HFD2_k127_601055_0 4Fe-4S binding domain - - - 7.48e-250 794.0
HFD2_k127_601055_1 Belongs to the carbamoyltransferase HypF family K04656 - - 2.335e-245 782.0
HFD2_k127_601055_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.00000005438 64.0
HFD2_k127_601055_11 AIR synthase related protein, N-terminal domain K04655 - - 0.000005732 59.0
HFD2_k127_601055_2 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 518.0
HFD2_k127_601055_3 Bacterial Ig-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 468.0
HFD2_k127_601055_4 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000001621 269.0
HFD2_k127_601055_5 Bacterial PH domain K08981 - - 0.00000000000000000000000000000000000000000000000000000000000000000000274 257.0
HFD2_k127_601055_6 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000009489 161.0
HFD2_k127_601055_7 Bacterial PH domain K09167 - - 0.00000000000000000007389 97.0
HFD2_k127_601055_8 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.0000000000000000004564 90.0
HFD2_k127_601055_9 Tetratricopeptide repeat - - - 0.0000000000000001793 91.0
HFD2_k127_6017642_0 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006908 606.0
HFD2_k127_6017642_1 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000882 445.0
HFD2_k127_6017642_2 Aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008381 413.0
HFD2_k127_6017642_3 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008576 287.0
HFD2_k127_6017642_4 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000000000000000000000000000000000000000000000000001478 229.0
HFD2_k127_6017642_5 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.00000000000000000000000000000003224 129.0
HFD2_k127_6017642_7 Flagellar basal body rod K02396,K03333 - 1.1.3.6 0.0000000002831 74.0
HFD2_k127_6028218_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 3.136e-276 880.0
HFD2_k127_6028218_1 Glutamine amidotransferases class-II K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 614.0
HFD2_k127_6028218_2 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006871 455.0
HFD2_k127_6028218_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004526 291.0
HFD2_k127_6028218_4 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000192 105.0
HFD2_k127_6028218_5 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.00000000000000000003363 106.0
HFD2_k127_6081465_0 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004527 611.0
HFD2_k127_6081465_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002036 280.0
HFD2_k127_6081465_2 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000000008237 175.0
HFD2_k127_6086044_0 ADP-glyceromanno-heptose 6-epimerase activity K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 484.0
HFD2_k127_6086044_1 G-rich domain on putative tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 316.0
HFD2_k127_6086044_2 Bacterial sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002081 282.0
HFD2_k127_6086044_3 nuclear chromosome segregation - - - 0.00000000000000000000000000000000000000000000000000000001035 213.0
HFD2_k127_6086044_4 SIS domain K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000004678 171.0
HFD2_k127_6086044_5 Domain of unknown function (DUF374) K09778 - - 0.000000000000000000000000000002726 125.0
HFD2_k127_6086044_6 PFAM Polysaccharide export protein K01991 - - 0.000000000000000000000003374 115.0
HFD2_k127_6086044_7 Uncharacterised nucleotidyltransferase - - - 0.00000000000000005117 95.0
HFD2_k127_6086044_8 lipolytic protein G-D-S-L family - - - 0.00000000000001146 88.0
HFD2_k127_6097201_0 Holliday junction DNA helicase ruvB C-terminus K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004747 453.0
HFD2_k127_6097201_1 Transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 306.0
HFD2_k127_6097201_2 PFAM asparagine synthase K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006653 295.0
HFD2_k127_6097201_3 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000002357 245.0
HFD2_k127_6097201_4 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000000000000000000000009057 190.0
HFD2_k127_6097201_5 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000005761 180.0
HFD2_k127_6097201_6 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000001615 146.0
HFD2_k127_6097201_7 COG NOG14600 non supervised orthologous group - - - 0.00000000000000000000000000000000000231 138.0
HFD2_k127_6097201_8 PFAM BioY protein K03523 - - 0.000000000000000000000114 105.0
HFD2_k127_6097201_9 Binding-protein-dependent transport system inner membrane component K02033,K15581 - - 0.00000000000005977 74.0
HFD2_k127_6135034_0 PFAM AMP-dependent synthetase and ligase K01897,K22319 - 6.1.3.1,6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005541 498.0
HFD2_k127_6135034_1 Exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 483.0
HFD2_k127_6135034_2 ABC transporter K06022,K06158,K10834 - 3.6.3.29,3.6.3.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008825 411.0
HFD2_k127_6135034_3 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006461 321.0
HFD2_k127_6141429_0 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 518.0
HFD2_k127_6141429_1 Major Facilitator K16211 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 393.0
HFD2_k127_6143607_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.974e-264 826.0
HFD2_k127_6143607_1 Amidohydrolase family K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004879 419.0
HFD2_k127_6143607_2 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000002145 218.0
HFD2_k127_6143607_3 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000004636 193.0
HFD2_k127_6143607_4 DivIVA protein K04074 - - 0.00000000000000000000000003384 116.0
HFD2_k127_6143607_5 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000009559 82.0
HFD2_k127_6143607_6 PFAM Formiminotransferase-cyclodeaminase - - - 0.00002439 54.0
HFD2_k127_615106_0 antibiotic biosynthetic process K01434 - 3.5.1.11 1.669e-227 733.0
HFD2_k127_615106_1 Aldo/keto reductase family K05882 - 1.1.1.91 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 291.0
HFD2_k127_615106_2 PFAM OsmC family protein K04063 - - 0.0000000000000000000000000000000000000000000000001288 181.0
HFD2_k127_615106_3 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.00000000000000000000000000000000000000000000001229 182.0
HFD2_k127_615106_4 'Cold-shock' DNA-binding domain - - - 0.0000000000000000000000000000000000000000000003141 174.0
HFD2_k127_615106_5 PFAM YbaK prolyl-tRNA synthetase associated region K19055 - - 0.00000000000000000000000000000000000000003419 161.0
HFD2_k127_615106_6 Low affinity iron permease - - - 0.000000000000000000000000000000000000006082 149.0
HFD2_k127_615106_7 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.00000000000000000463 93.0
HFD2_k127_615106_8 transposition, DNA-mediated K02342 - 2.7.7.7 0.0000000000000001241 92.0
HFD2_k127_6157760_0 Pfam:DUF2029 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003911 430.0
HFD2_k127_6157760_1 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 307.0
HFD2_k127_6157760_2 regulation of methylation-dependent chromatin silencing - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 299.0
HFD2_k127_6157760_3 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.000000000000000000000000000000000000000000000000000000000000000000004308 242.0
HFD2_k127_6157760_4 glyoxalase bleomycin resistance protein dioxygenase K07032 - - 0.00000000000000000000000000000000000000000000000000000000001059 209.0
HFD2_k127_6157760_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000005659 98.0
HFD2_k127_6157760_6 - - - - 0.000000000000000002299 98.0
HFD2_k127_6157760_7 Amidase - - - 0.0000000000000961 71.0
HFD2_k127_6180180_0 PFAM tRNA synthetase, class II (G, H, P and S) K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008473 424.0
HFD2_k127_6180180_1 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 - 6.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 402.0
HFD2_k127_6180180_2 PQQ enzyme repeat - - - 0.000000002455 69.0
HFD2_k127_619086_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 412.0
HFD2_k127_619086_1 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000001601 260.0
HFD2_k127_619086_2 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.0000000000000000000000000000000000007601 145.0
HFD2_k127_6192403_0 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006785 585.0
HFD2_k127_6192403_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 356.0
HFD2_k127_6192403_2 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 334.0
HFD2_k127_6192403_3 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005175 334.0
HFD2_k127_6192403_4 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06137 - 1.3.3.11 0.000000000000000000000000000000000000000000000000000000000000000000001445 244.0
HFD2_k127_6192403_5 COGs COG1253 Hemolysins and related protein containing CBS domains - - - 0.00000000000000000000000000000000000000000000000000000000000000002111 241.0
HFD2_k127_6192403_6 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000000000000000000000000000003173 203.0
HFD2_k127_6192403_7 ECF sigma factor - - - 0.00000000000000000000000000000000000000000007832 170.0
HFD2_k127_6192403_8 CarD-like/TRCF domain K07736 - - 0.000000000000000000000000000000000005672 142.0
HFD2_k127_6192403_9 Fibronectin-binding A domain protein - - - 0.000000000000000000000000000132 132.0
HFD2_k127_6219250_0 Enoyl-CoA hydratase/isomerase K15513 - 4.1.2.44 1.905e-211 670.0
HFD2_k127_6219250_1 benzoyl-CoA oxygenase K15512 - 1.14.13.208 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 573.0
HFD2_k127_6219250_10 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K15546 - - 0.000000000000000000000000000000000000000000000003845 192.0
HFD2_k127_6219250_11 Cytochrome C oxidase subunit II, periplasmic domain K02275 - 1.9.3.1 0.00000000000000000000000000000000000000006623 160.0
HFD2_k127_6219250_12 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000001837 147.0
HFD2_k127_6219250_13 Cold shock protein domain K03704 - - 0.000000000000000000000000008232 111.0
HFD2_k127_6219250_14 Cytochrome C oxidase subunit II, periplasmic domain K02275 - 1.9.3.1 0.00000000000000000003402 96.0
HFD2_k127_6219250_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335,K17998,K18331 - 1.12.1.3,1.12.1.4,1.6.5.3 0.000000000295 69.0
HFD2_k127_6219250_16 ASPIC and UnbV - - - 0.0000002778 52.0
HFD2_k127_6219250_2 cytochrome c oxidase subunit I K02274 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 496.0
HFD2_k127_6219250_3 Domain of Unknown Function (DUF748) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003542 439.0
HFD2_k127_6219250_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 315.0
HFD2_k127_6219250_5 Predicted membrane protein (DUF2238) K08984 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003188 273.0
HFD2_k127_6219250_6 Protein involved in cellulose biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004459 272.0
HFD2_k127_6219250_7 PFAM thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000001719 224.0
HFD2_k127_6219250_8 Proline dehydrogenase K00318 - - 0.000000000000000000000000000000000000000000000000000003379 214.0
HFD2_k127_6219250_9 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000001238 192.0
HFD2_k127_6226014_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1605.0
HFD2_k127_6226014_1 COG0823 Periplasmic component of the Tol biopolymer transport system - - - 0.0 1289.0
HFD2_k127_6226014_10 Domain of unknown function (DUF4920) - - - 0.00000000000000000000000000000000007733 147.0
HFD2_k127_6226014_2 COG0488 ATPase components of ABC transporters with duplicated ATPase domains - - - 1.321e-251 790.0
HFD2_k127_6226014_3 Protein kinase domain K12132 - 2.7.11.1 5.852e-212 689.0
HFD2_k127_6226014_4 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol - - - 3.777e-209 663.0
HFD2_k127_6226014_5 Multicopper oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 598.0
HFD2_k127_6226014_6 TonB-dependent Receptor Plug Domain K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 550.0
HFD2_k127_6226014_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004711 417.0
HFD2_k127_6226014_8 Putative neutral zinc metallopeptidase K07054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004352 328.0
HFD2_k127_6226014_9 Family of unknown function (DUF1028) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001217 282.0
HFD2_k127_623136_0 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 512.0
HFD2_k127_623136_1 Belongs to the thiolase family K00632 - 2.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 394.0
HFD2_k127_623136_2 PFAM peptidase T2 asparaginase 2 K01444,K13051 - 3.4.19.5,3.5.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 369.0
HFD2_k127_623136_3 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356,K03503 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000002209 222.0
HFD2_k127_623136_4 PFAM periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000002603 175.0
HFD2_k127_623136_5 haloacid dehalogenase-like hydrolase K01079 - 3.1.3.3 0.0000000000000000000000000000000000003238 147.0
HFD2_k127_623136_6 capsule polysaccharide biosynthetic process - - - 0.00000002763 65.0
HFD2_k127_6269834_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006637 563.0
HFD2_k127_6269834_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003215 509.0
HFD2_k127_6269834_10 Protein of unknown function (DUF1326) - - - 0.0000000000000000000000000000000000001618 151.0
HFD2_k127_6269834_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000003757 153.0
HFD2_k127_6269834_12 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K00330 - 1.6.5.3 0.0000000000000000000000000000000001078 137.0
HFD2_k127_6269834_13 guanyl-nucleotide exchange factor activity - - - 0.000000000000000000000000000000002496 152.0
HFD2_k127_6269834_14 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02768,K02769,K02770,K02806 - 2.7.1.202 0.000000000000000000000000000214 120.0
HFD2_k127_6269834_15 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000008468 117.0
HFD2_k127_6269834_16 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000001187 117.0
HFD2_k127_6269834_18 AntiSigma factor - - - 0.0004539 51.0
HFD2_k127_6269834_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00334,K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002714 473.0
HFD2_k127_6269834_3 formate dehydrogenase (NAD+) activity K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007944 397.0
HFD2_k127_6269834_4 quinone binding K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000438 399.0
HFD2_k127_6269834_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008412 369.0
HFD2_k127_6269834_6 Cysteine synthase K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 331.0
HFD2_k127_6269834_7 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000009496 192.0
HFD2_k127_6269834_8 2 iron, 2 sulfur cluster binding K00334,K00335 - 1.6.5.3 0.000000000000000000000000000000000000000003521 175.0
HFD2_k127_6269834_9 HEAT repeats - - - 0.000000000000000000000000000000000000000005498 162.0
HFD2_k127_6279468_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1987.0
HFD2_k127_6279468_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 1.09e-282 884.0
HFD2_k127_6279468_2 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004349 484.0
HFD2_k127_6279468_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 437.0
HFD2_k127_6279468_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.000000000000000000000000000000000000000000000000000000000000000133 231.0
HFD2_k127_6279468_5 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000001707 221.0
HFD2_k127_6304901_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 8.664e-319 1017.0
HFD2_k127_6304901_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000002148 256.0
HFD2_k127_6304901_2 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000001382 90.0
HFD2_k127_6304901_3 Domain of unknown function (DUF4388) - - - 0.000007993 53.0
HFD2_k127_6360415_0 PFAM carboxyl transferase K01615 - 4.1.1.70 5.413e-241 758.0
HFD2_k127_6360415_1 PFAM Carbamoyl-phosphate synthase L chain, ATP binding domain K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 497.0
HFD2_k127_6374655_0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 1.87e-249 799.0
HFD2_k127_6374655_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 490.0
HFD2_k127_6374655_10 Belongs to the UPF0337 (CsbD) family - - - 0.0000000000000000000004913 100.0
HFD2_k127_6374655_11 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00002351 56.0
HFD2_k127_6374655_2 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 473.0
HFD2_k127_6374655_3 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004253 411.0
HFD2_k127_6374655_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 396.0
HFD2_k127_6374655_5 O-linked GlcNAc transferase-putative TPR-containing transmembrane protein - - - 0.0000000000000000000000000000000000000000000000000000000002595 226.0
HFD2_k127_6374655_6 arylsulfatase A - - - 0.0000000000000000000000000000000000000000000000000000002446 219.0
HFD2_k127_6374655_7 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000003094 182.0
HFD2_k127_6374655_8 Phosphodiester glycosidase - - - 0.00000000000000000000000000000000000000000002026 171.0
HFD2_k127_6374655_9 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.00000000000000000000007002 107.0
HFD2_k127_6426492_0 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001621 272.0
HFD2_k127_6426492_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000006549 224.0
HFD2_k127_6426492_2 COG2146 Ferredoxin subunits of nitrite reductase and K00363 - 1.7.1.15 0.0000000000000000000000000001333 120.0
HFD2_k127_6426492_3 Redoxin - - - 0.00000000000000002369 87.0
HFD2_k127_6432895_0 choline dehydrogenase activity - - - 5.237e-243 773.0
HFD2_k127_6432895_1 Glucose dehydrogenase C-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009659 413.0
HFD2_k127_6432895_2 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003677 284.0
HFD2_k127_6432895_3 Amylo-alpha-1,6-glucosidase - - - 0.000000000000000000000000000000000000005496 151.0
HFD2_k127_6438105_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 5.104e-309 960.0
HFD2_k127_6438105_1 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008345 603.0
HFD2_k127_6438105_2 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 376.0
HFD2_k127_6438105_3 conserved protein UCP033924 - - - 0.00000000000000000000000000000000000005969 158.0
HFD2_k127_6438105_4 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000006346 79.0
HFD2_k127_6457307_0 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007488 361.0
HFD2_k127_6457307_1 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 349.0
HFD2_k127_6457307_10 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000006213 80.0
HFD2_k127_6457307_11 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000002332 72.0
HFD2_k127_6457307_12 Protein tyrosine kinase K12132 - 2.7.11.1 0.0008198 50.0
HFD2_k127_6457307_2 Kelch motif - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001099 284.0
HFD2_k127_6457307_3 Protein of unknown function, DUF255 K06888 - - 0.0000000000000000000000000000000000000000000000000000000000000001117 247.0
HFD2_k127_6457307_4 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000000001104 179.0
HFD2_k127_6457307_5 ECF sigma factor - - - 0.0000000000000000000000000000000000000005371 156.0
HFD2_k127_6457307_6 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000009245 130.0
HFD2_k127_6457307_8 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000001212 100.0
HFD2_k127_6457307_9 Thrombospondin type 3 repeat - - - 0.000000000000000002791 101.0
HFD2_k127_6482128_0 protein related to plant photosystem II stability assembly factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008436 546.0
HFD2_k127_6482128_1 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006992 353.0
HFD2_k127_6482128_2 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003388 278.0
HFD2_k127_6482128_3 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001845 243.0
HFD2_k127_6482128_4 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000002014 137.0
HFD2_k127_6482128_5 ThiS family K03636 - - 0.00000000000000000000005909 100.0
HFD2_k127_6482128_6 nerve growth factor signaling pathway K12460 - - 0.0000000000000000001685 96.0
HFD2_k127_6482128_7 Putative adhesin - - - 0.00000000000000001134 95.0
HFD2_k127_6542815_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000645 600.0
HFD2_k127_6542815_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 328.0
HFD2_k127_6542815_2 SpoIVB peptidase S55 K00973,K02414,K21449 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 316.0
HFD2_k127_6542815_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004155 292.0
HFD2_k127_6542815_4 cellulose binding K01179,K21449 - 3.2.1.4 0.00003529 49.0
HFD2_k127_661583_0 metallocarboxypeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 326.0
HFD2_k127_661583_1 PAS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000142 270.0
HFD2_k127_661583_2 Thioesterase involved in non-ribosomal peptide biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000001799 229.0
HFD2_k127_661583_3 ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000003065 240.0
HFD2_k127_661583_4 Belongs to the P-Pant transferase superfamily K06133 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008897,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0019752,GO:0019878,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.00000000000000000000000000000000000000000000004954 177.0
HFD2_k127_661583_5 COG COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000000000000000000001986 127.0
HFD2_k127_6618936_0 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 328.0
HFD2_k127_6618936_1 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000001431 244.0
HFD2_k127_6618936_2 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000001309 63.0
HFD2_k127_6618936_3 Putative ABC exporter - - - 0.0000123 52.0
HFD2_k127_6670647_0 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000002605 102.0
HFD2_k127_6670647_1 membrane K11622 - - 0.000005193 58.0
HFD2_k127_668543_0 X-Pro dipeptidyl-peptidase (S15 family) - - - 1.118e-274 869.0
HFD2_k127_668543_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00122,K00335 - 1.17.1.9,1.6.5.3 9.117e-219 706.0
HFD2_k127_668543_2 2Fe-2S iron-sulfur cluster binding domain K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 413.0
HFD2_k127_668543_3 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 311.0
HFD2_k127_668543_4 Yqey-like protein K09117 - - 0.0000000000000000000000000000000001075 140.0
HFD2_k127_668543_5 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000005573 107.0
HFD2_k127_6698207_0 CHAT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 494.0
HFD2_k127_6698207_1 Beta-eliminating lyase K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 358.0
HFD2_k127_6698207_10 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0001101,GO:0001666,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0010035,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0036293,GO:0042221,GO:0044419,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051704,GO:0060255,GO:0065007,GO:0070482,GO:0080090,GO:1901700,GO:1903506,GO:2000112,GO:2001141 - 0.000000002602 65.0
HFD2_k127_6698207_11 AntiSigma factor - - - 0.0008243 50.0
HFD2_k127_6698207_2 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001907 282.0
HFD2_k127_6698207_3 Short chain dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000005303 230.0
HFD2_k127_6698207_4 Haloacid dehalogenase-like hydrolase K07025 - - 0.00000000000000000000000000000000000005187 152.0
HFD2_k127_6698207_5 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.00000000000000000000000000000005412 137.0
HFD2_k127_6698207_6 Iron-sulfur cluster assembly accessory protein K13628 - - 0.0000000000000000000000000000003087 125.0
HFD2_k127_6698207_7 transcriptional regulator, Rrf2 family - - - 0.000000000000000000000000000354 119.0
HFD2_k127_6698207_8 Uncharacterized conserved protein (DUF2203) - - - 0.000000000000000000009936 96.0
HFD2_k127_669940_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000315 481.0
HFD2_k127_669940_1 Cell shape determining protein MreB Mrl K03569 - - 0.000000007267 59.0
HFD2_k127_6714900_0 ATPase associated with various cellular K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 458.0
HFD2_k127_6714900_1 von Willebrand factor (vWF) type A domain K07114,K12511 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008458 349.0
HFD2_k127_6714900_2 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 341.0
HFD2_k127_6714900_3 von Willebrand factor (vWF) type A domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008034 354.0
HFD2_k127_6714900_4 histidine kinase HAMP region domain protein K03406 - - 0.000000000000000000000000000000000000000000000000000000000000003229 237.0
HFD2_k127_6714900_5 - - - - 0.000000000000000005872 100.0
HFD2_k127_6714900_6 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.00000000000000003878 88.0
HFD2_k127_6714900_7 SMART CheW domain protein K03408 - - 0.000000002003 66.0
HFD2_k127_6715832_0 RNB K01147 - 3.1.13.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008989 297.0
HFD2_k127_6715832_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000002449 273.0
HFD2_k127_6715832_2 Methyltransferase, chemotaxis proteins K00575,K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000148 249.0
HFD2_k127_6715832_3 COG0665 Glycine D-amino acid oxidases (deaminating) K19746 - 1.4.99.6 0.0000000000000000000000000000000000000003412 172.0
HFD2_k127_6715832_4 Protein containing von Willebrand factor type A (VWA) domain K07161 - - 0.00000000000000000000000000000001846 135.0
HFD2_k127_6752666_0 Capsular polysaccharide biosynthesis protein CapK K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000002885 263.0
HFD2_k127_6752666_1 PFAM Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000005433 98.0
HFD2_k127_6837059_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004531 438.0
HFD2_k127_6837059_1 amidohydrolase - - - 0.0000000000000000000000000000000000000007375 169.0
HFD2_k127_6837059_2 Transmembrane and - - - 0.00000000000000000000000000000000000005418 163.0
HFD2_k127_6837059_3 rna polymerase alpha K03040 - 2.7.7.6 0.0001791 53.0
HFD2_k127_6916842_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002875 389.0
HFD2_k127_6916842_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621,K21576,K21577 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.21.4.2,1.21.4.3,1.21.4.4,2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000007975 220.0
HFD2_k127_6916842_2 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000000000000009695 100.0
HFD2_k127_6916842_3 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000103 105.0
HFD2_k127_6916842_4 heat shock protein binding K05516,K05801 - - 0.00000004775 66.0
HFD2_k127_6916842_5 peptidyl-tyrosine sulfation - - - 0.0003477 53.0
HFD2_k127_6920159_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885,K09698 - 6.1.1.17,6.1.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 418.0
HFD2_k127_6920159_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 325.0
HFD2_k127_6920159_2 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 319.0
HFD2_k127_6920159_3 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000003839 213.0
HFD2_k127_6920159_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000000000000000000000000000000000001131 199.0
HFD2_k127_6920159_5 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000002927 193.0
HFD2_k127_6920159_6 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000001985 169.0
HFD2_k127_6920159_8 - - - - 0.0000537 52.0
HFD2_k127_6942126_0 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008943 501.0
HFD2_k127_6942126_1 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000009784 247.0
HFD2_k127_6942126_2 belongs to the iron- containing alcohol dehydrogenase family K04072 - 1.1.1.1,1.2.1.10 0.0000000000000000000000000000003397 129.0
HFD2_k127_6942126_3 - - - - 0.000000001558 71.0
HFD2_k127_6942126_4 Carrier of the growing fatty acid chain in fatty acid biosynthesis - - - 0.00001567 53.0
HFD2_k127_698869_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.145e-248 778.0
HFD2_k127_698869_1 4-Hydroxyphenylpyruvate dioxygenase K00457,K16421 GO:0003674,GO:0003824,GO:0003868,GO:0006082,GO:0006520,GO:0006570,GO:0006572,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009987,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0051213,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.27,1.13.11.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 392.0
HFD2_k127_698869_10 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 - 0.000000000000000000000000000000000000007839 147.0
HFD2_k127_698869_11 MbtH-like protein K05375 - - 0.00000000000000000000000000000118 128.0
HFD2_k127_698869_12 Pfam:HxxPF_rpt - - - 0.0000000000000000000000000006875 123.0
HFD2_k127_698869_13 Carboxypeptidase regulatory-like domain - - - 0.000000292 59.0
HFD2_k127_698869_2 PFAM aminotransferase class I and II K05825 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005861 390.0
HFD2_k127_698869_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 310.0
HFD2_k127_698869_4 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003673 289.0
HFD2_k127_698869_5 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003161 279.0
HFD2_k127_698869_6 Major Facilitator K00836 - 2.6.1.76 0.00000000000000000000000000000000000000000000000000000000000000000001147 258.0
HFD2_k127_698869_7 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000001303 239.0
HFD2_k127_698869_8 - - - - 0.0000000000000000000000000000000000000000005832 168.0
HFD2_k127_698869_9 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.00000000000000000000000000000000000000001217 175.0
HFD2_k127_7003475_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 4.326e-201 649.0
HFD2_k127_7003475_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K04105,K04110 - 6.2.1.25,6.2.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000448 607.0
HFD2_k127_7003475_2 Alpha-2-Macroglobulin K06894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 562.0
HFD2_k127_7003475_3 penicillin binding K05367 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007443 448.0
HFD2_k127_7003475_4 2 iron, 2 sulfur cluster binding K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000002488 196.0
HFD2_k127_7003475_5 membrane transporter protein K07090 - - 0.00000000000004733 83.0
HFD2_k127_7005120_0 histidine kinase HAMP region domain protein K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009335 328.0
HFD2_k127_7005120_1 PFAM response regulator receiver K07657,K07664 - - 0.0000000000000000000000000000000000000000000000000000000000000000005986 237.0
HFD2_k127_7005120_2 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000007941 226.0
HFD2_k127_7005120_3 Protein of unknown function, DUF255 K06888 - - 0.00000000000000000000000000000002388 136.0
HFD2_k127_7005120_4 Phosphate-selective porin O and P - - - 0.0000000000000000000000000000003985 143.0
HFD2_k127_7005120_5 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000007721 115.0
HFD2_k127_7005120_6 lipolytic protein G-D-S-L family K20306 - - 0.0000000000000000000001007 114.0
HFD2_k127_7005120_7 Glycerol-3-phosphate acyltransferase - - - 0.0000000000000000000002753 105.0
HFD2_k127_7005120_8 COG0457 FOG TPR repeat - - - 0.000003845 59.0
HFD2_k127_7005120_9 - - - - 0.0001224 56.0
HFD2_k127_7022339_0 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 349.0
HFD2_k127_7022339_1 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005645 332.0
HFD2_k127_7022339_2 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007829 289.0
HFD2_k127_7022339_3 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000000000007706 216.0
HFD2_k127_7022339_4 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000001081 188.0
HFD2_k127_7022339_5 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000005357 126.0
HFD2_k127_7022339_6 protein conserved in bacteria K09778 - - 0.000000000001305 70.0
HFD2_k127_7040047_0 transport system permease component K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 603.0
HFD2_k127_7040047_1 phosphate transport system K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 584.0
HFD2_k127_7040047_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 396.0
HFD2_k127_7040047_3 TIGRFAM cysteine desulfurase family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005384 379.0
HFD2_k127_7040047_4 involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004456 347.0
HFD2_k127_7040047_5 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000001926 249.0
HFD2_k127_7040047_6 Peptidase C26 K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000001099 218.0
HFD2_k127_7040047_7 TIGRFAM Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000005722 172.0
HFD2_k127_7040047_8 Belongs to the TrpC family K01609 - 4.1.1.48 0.000000000000000000000000000000004429 141.0
HFD2_k127_7040047_9 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000004138 96.0
HFD2_k127_7055335_0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009283 439.0
HFD2_k127_7055335_1 ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001868 276.0
HFD2_k127_7055335_2 CHAT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001006 265.0
HFD2_k127_7055335_3 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000006069 220.0
HFD2_k127_7057895_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0 1392.0
HFD2_k127_7057895_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 479.0
HFD2_k127_7057895_10 PFAM regulatory protein LuxR - - - 0.0000000000000000000000000000000000000000000000000000000000002381 218.0
HFD2_k127_7057895_11 Fibronectin type 3 domain - - - 0.000000000000000000000000000000000000000000000994 191.0
HFD2_k127_7057895_12 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( K02823 - - 0.00000000000000000000000000000000000000002364 163.0
HFD2_k127_7057895_13 Response regulator receiver - - - 0.00000000000000000000000000000000004781 151.0
HFD2_k127_7057895_15 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000002089 103.0
HFD2_k127_7057895_16 cellulase activity - - - 0.00000000004675 77.0
HFD2_k127_7057895_2 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 362.0
HFD2_k127_7057895_3 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 338.0
HFD2_k127_7057895_4 Catalyzes the conversion of dihydroorotate to orotate K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006161 345.0
HFD2_k127_7057895_5 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 322.0
HFD2_k127_7057895_6 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001555 265.0
HFD2_k127_7057895_7 Belongs to the purine pyrimidine phosphoribosyltransferase family. PyrR subfamily K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000001579 244.0
HFD2_k127_7057895_8 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000003928 252.0
HFD2_k127_7057895_9 Two component transcriptional regulator, winged helix family K07658,K07668 - - 0.0000000000000000000000000000000000000000000000000000000000000000009199 237.0
HFD2_k127_7078821_0 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 463.0
HFD2_k127_7078821_1 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 313.0
HFD2_k127_7078821_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007284 300.0
HFD2_k127_7078821_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000004267 220.0
HFD2_k127_7078821_4 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000005693 196.0
HFD2_k127_7078821_5 Rubrerythrin K22405 - 1.6.3.4 0.00000000000000000000000000000000000000000000001308 183.0
HFD2_k127_7078821_6 PFAM Peptidase M16 inactive domain K07263 - - 0.0000000000000000000000000000000000000000000002165 177.0
HFD2_k127_7078821_7 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000002517 130.0
HFD2_k127_7118503_0 (ABC) transporter K15738 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003306 533.0
HFD2_k127_7118503_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000001167 266.0
HFD2_k127_7170401_0 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007826 624.0
HFD2_k127_7170401_1 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008541 323.0
HFD2_k127_7170401_2 PFAM SAF domain K02279 - - 0.0000000000000000000000000000000000000000000000001619 187.0
HFD2_k127_7170401_3 Type IV leader peptidase family K02278 - 3.4.23.43 0.000000000000000008536 91.0
HFD2_k127_7170401_4 TadE-like protein - - - 0.0000000007509 70.0
HFD2_k127_7170401_5 Tetratricopeptide repeat - - - 0.000000001792 71.0
HFD2_k127_7170401_6 Sensor diguanylate cyclase, GAF domain-containing - - - 0.0000002543 63.0
HFD2_k127_7170401_7 - - - - 0.0001124 46.0
HFD2_k127_726268_0 synthetase (ADP forming), alpha K01905,K09181,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004621 484.0
HFD2_k127_726268_1 Kelch motif - - - 0.00000000000000000000000000000000000000000000000000000001548 222.0
HFD2_k127_726268_2 - - - - 0.00000000000000000000000000000002787 130.0
HFD2_k127_726268_3 TPR repeat - - - 0.000001332 61.0
HFD2_k127_7294837_0 PFAM Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 530.0
HFD2_k127_7294837_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000006163 123.0
HFD2_k127_7294837_2 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.000000000000000000000000002221 116.0
HFD2_k127_7331625_0 Belongs to the ClpA ClpB family K03696 - - 2.399e-220 697.0
HFD2_k127_7331625_1 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004696 324.0
HFD2_k127_7331625_10 TonB C terminal K03832 - - 0.000008862 57.0
HFD2_k127_7331625_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 340.0
HFD2_k127_7331625_3 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004688 292.0
HFD2_k127_7331625_4 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000002681 279.0
HFD2_k127_7331625_5 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000005654 211.0
HFD2_k127_7331625_6 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K16363 - 3.5.1.108,4.2.1.59 0.000000000000000000000000000000000000000000000000001488 186.0
HFD2_k127_7331625_7 QueT transporter K16928 - - 0.000000000000000000000000000000000000000000001408 175.0
HFD2_k127_7331625_8 conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family - - - 0.000000000000000000000000004223 120.0
HFD2_k127_7331625_9 Outer membrane protein (OmpH-like) K06142 - - 0.0000002742 61.0
HFD2_k127_7352193_0 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000001359 248.0
HFD2_k127_7352193_1 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000000000000000008463 208.0
HFD2_k127_7352193_2 D,d-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000000000001361 205.0
HFD2_k127_7352193_3 arylsulfatase activity K01133 - 3.1.6.6 0.00000000000000000000000000000000000000000000000000008146 203.0
HFD2_k127_7352193_4 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000001436 130.0
HFD2_k127_7352193_5 COG3119 Arylsulfatase A and related enzymes K01130 - 3.1.6.1 0.0000000000000000000000005535 117.0
HFD2_k127_7398242_0 Elongation factor SelB, winged helix K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 520.0
HFD2_k127_7398242_1 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001581 254.0
HFD2_k127_7398242_2 PFAM glycosyl transferase family 9 - - - 0.000000000000000000000000000000000000000000000000004234 189.0
HFD2_k127_7398242_3 Protein of unknown function (DUF507) K09804 - - 0.0000000000000366 77.0
HFD2_k127_7398242_4 Protein of unknown function (DUF507) K09804 - - 0.00000000000111 75.0
HFD2_k127_7398242_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000001408 69.0
HFD2_k127_7432908_0 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 550.0
HFD2_k127_7432908_1 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007132 533.0
HFD2_k127_7432908_10 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000002106 194.0
HFD2_k127_7432908_11 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000007775 197.0
HFD2_k127_7432908_12 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 0.00000000000000000000000000000000000000004863 155.0
HFD2_k127_7432908_13 O-antigen ligase like membrane protein - - - 0.00000000000002441 87.0
HFD2_k127_7432908_14 Glycosyl transferases group 1 - - - 0.0000000002409 63.0
HFD2_k127_7432908_2 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003884 387.0
HFD2_k127_7432908_3 Heparinase II/III N-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005221 308.0
HFD2_k127_7432908_4 Required for morphogenesis under gluconeogenic growth conditions - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001573 263.0
HFD2_k127_7432908_5 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002256 253.0
HFD2_k127_7432908_6 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000001797 237.0
HFD2_k127_7432908_7 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000001373 228.0
HFD2_k127_7432908_8 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000003701 217.0
HFD2_k127_7432908_9 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000001829 198.0
HFD2_k127_7447070_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 447.0
HFD2_k127_7447070_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 441.0
HFD2_k127_7447070_2 PFAM Thiamine pyrophosphate K00170,K00187 - 1.2.7.1,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004357 372.0
HFD2_k127_7447070_3 glutamate synthase (NADPH) K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000001312 238.0
HFD2_k127_7447070_4 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000004025 215.0
HFD2_k127_7447070_5 glutamate synthase - - - 0.00000000000000000000000002369 120.0
HFD2_k127_7474101_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 399.0
HFD2_k127_7474101_1 Dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 393.0
HFD2_k127_7474101_10 Peptidase family M23 K21471 - - 0.000000000000000000000000000009393 134.0
HFD2_k127_7474101_11 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000000327 108.0
HFD2_k127_7474101_12 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000003668 108.0
HFD2_k127_7474101_13 Glutaredoxin-like domain (DUF836) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000001341 79.0
HFD2_k127_7474101_14 - - - - 0.000000000006294 72.0
HFD2_k127_7474101_15 PFAM VanZ like - - - 0.00000007473 62.0
HFD2_k127_7474101_2 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 318.0
HFD2_k127_7474101_3 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000000000004826 184.0
HFD2_k127_7474101_4 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000000001441 179.0
HFD2_k127_7474101_5 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000001279 164.0
HFD2_k127_7474101_6 repeat-containing protein - - - 0.000000000000000000000000000000000000000001022 179.0
HFD2_k127_7474101_7 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000000000436 172.0
HFD2_k127_7474101_8 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000001032 153.0
HFD2_k127_7474101_9 Could be involved in septation K06412 - - 0.00000000000000000000000000000004829 128.0
HFD2_k127_7570889_0 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003566 539.0
HFD2_k127_7570889_1 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008645 344.0
HFD2_k127_7570889_2 translation release factor activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003572 297.0
HFD2_k127_7570889_3 2-oxoglutarate dehydrogenase, E1 K00164 - 1.2.4.2 0.0000000000000000000000000000000004442 134.0
HFD2_k127_7570889_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000003354 138.0
HFD2_k127_7570889_5 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000003787 93.0
HFD2_k127_7570889_6 - - - - 0.000000006912 59.0
HFD2_k127_7583532_0 leucyl-tRNA aminoacylation K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 3.812e-289 917.0
HFD2_k127_7583532_1 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000002145 104.0
HFD2_k127_7583532_2 Lipopolysaccharide-assembly - - - 0.000000000000000000009628 104.0
HFD2_k127_7583532_3 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.000000000000001376 87.0
HFD2_k127_7583532_4 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000002619 73.0
HFD2_k127_7596098_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1360.0
HFD2_k127_7596098_1 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007814 497.0
HFD2_k127_7596098_10 OprF membrane domain K03286 - - 0.0000000000000000000000000000000000000000000000000001016 197.0
HFD2_k127_7596098_11 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000002141 112.0
HFD2_k127_7596098_12 AMP binding - - - 0.00000000000005406 82.0
HFD2_k127_7596098_13 alpha beta - - - 0.0000000000001505 83.0
HFD2_k127_7596098_2 Transketolase, pyrimidine binding domain K00167 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003134 452.0
HFD2_k127_7596098_3 e3 binding domain K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 443.0
HFD2_k127_7596098_4 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 347.0
HFD2_k127_7596098_5 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 327.0
HFD2_k127_7596098_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006484 316.0
HFD2_k127_7596098_7 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000000001027 234.0
HFD2_k127_7596098_8 squalene-associated FAD-dependent desaturase K21677 - 1.17.8.1 0.000000000000000000000000000000000000000000000000000000000000004818 237.0
HFD2_k127_7596098_9 Na+/Pi-cotransporter - - - 0.000000000000000000000000000000000000000000000000000000009402 206.0
HFD2_k127_7637632_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1047.0
HFD2_k127_7637632_1 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000002515 250.0
HFD2_k127_7637632_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000006106 243.0
HFD2_k127_7637632_3 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000001529 147.0
HFD2_k127_7640017_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 596.0
HFD2_k127_7640017_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 609.0
HFD2_k127_7640017_10 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000003024 222.0
HFD2_k127_7640017_11 FecR protein - - - 0.00000000000000000000000000000000000000000000000003651 202.0
HFD2_k127_7640017_12 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000181 183.0
HFD2_k127_7640017_13 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000353 128.0
HFD2_k127_7640017_14 SEC-C motif - - - 0.000000000000000001857 86.0
HFD2_k127_7640017_15 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000002551 89.0
HFD2_k127_7640017_16 Acetyltransferase (GNAT) family - - - 0.000000000000005737 79.0
HFD2_k127_7640017_17 Acetyltransferase (GNAT) domain - - - 0.000000006634 59.0
HFD2_k127_7640017_18 RibD C-terminal domain - - - 0.000000006681 57.0
HFD2_k127_7640017_2 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 556.0
HFD2_k127_7640017_3 MgsA AAA+ ATPase C terminal K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 511.0
HFD2_k127_7640017_4 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 400.0
HFD2_k127_7640017_5 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001185 282.0
HFD2_k127_7640017_6 cytosine at position 967 (m5C967) of 16S rRNA K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000001856 262.0
HFD2_k127_7640017_7 Methyltransferase, chemotaxis proteins K00575,K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000003798 261.0
HFD2_k127_7640017_8 mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000005769 250.0
HFD2_k127_7640017_9 dihydrofolate reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000005079 226.0
HFD2_k127_7646140_0 Glycerol-3-phosphate dehydrogenase K00057 GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0046167,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901576 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000001261 251.0
HFD2_k127_7646140_1 Belongs to the arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000003884 248.0
HFD2_k127_7646140_2 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000001186 151.0
HFD2_k127_7646140_3 S1/P1 Nuclease - - - 0.000000000000000000000000000000000009201 151.0
HFD2_k127_7646140_4 Protein of unknown function (DUF1698) - - - 0.000000000000000001107 96.0
HFD2_k127_7646140_5 tRNA wobble adenosine to inosine editing - - - 0.00000000000000881 77.0
HFD2_k127_7646140_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000313 62.0
HFD2_k127_7646140_7 - - - - 0.0001808 48.0
HFD2_k127_7697688_0 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 408.0
HFD2_k127_7697688_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000001068 241.0
HFD2_k127_7697688_2 Evidence 5 No homology to any previously reported sequences K09005 - - 0.00000000000000000000000000001474 125.0
HFD2_k127_7697688_3 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0033554,GO:0034599,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0070887 - 0.0000000000000001681 83.0
HFD2_k127_7697688_4 PFAM Preprotein translocase SecG subunit K03075 - - 0.000000000000000202 83.0
HFD2_k127_7730801_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03671,K22345 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9,4.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 402.0
HFD2_k127_7730801_1 Glycosyl transferase, family 2 - - - 0.00003912 54.0
HFD2_k127_7806406_0 SpoIVB peptidase S55 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 341.0
HFD2_k127_7806406_1 Belongs to the peptidase S8 family K17734 - - 0.000000000000000000000000000000000000000000000000000000000000000000008667 250.0
HFD2_k127_7806406_2 COG3209 Rhs family protein - - - 0.00000000000000000000000000000000001574 147.0
HFD2_k127_7819879_0 peptidase S9 prolyl oligopeptidase active site - GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008239,GO:0009056,GO:0009987,GO:0016787,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044464,GO:0046983,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 7.208e-244 772.0
HFD2_k127_7819879_1 Dehydrogenase E1 component K11381 - 1.2.4.4 6.563e-203 652.0
HFD2_k127_7819879_2 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000448 321.0
HFD2_k127_7819879_3 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 291.0
HFD2_k127_7819879_4 Domain of unknown function (DUF3524) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008797 287.0
HFD2_k127_7859617_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 404.0
HFD2_k127_7859617_1 Biotin-lipoyl like K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003821 280.0
HFD2_k127_7859617_2 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000008725 210.0
HFD2_k127_7866817_0 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 447.0
HFD2_k127_7866817_1 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000008038 268.0
HFD2_k127_7866817_2 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001897 266.0
HFD2_k127_7866817_3 PFAM beta-lactamase domain protein K06167 - 3.1.4.55 0.0000000000000000000000000000000000000000000000000000000000000000000005813 259.0
HFD2_k127_7866817_4 cell redox homeostasis - - - 0.0000000000695 72.0
HFD2_k127_7866817_5 Peptidase family M28 - - - 0.00000000229 70.0
HFD2_k127_7866817_6 - - - - 0.00005565 56.0
HFD2_k127_7883063_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 514.0
HFD2_k127_7883063_1 Elongator protein 3, MiaB family, Radical SAM K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006326 453.0
HFD2_k127_7883063_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007128 441.0
HFD2_k127_7883063_3 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 325.0
HFD2_k127_7883063_4 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.00000000000000003801 94.0
HFD2_k127_788685_0 proline dipeptidase activity K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 427.0
HFD2_k127_788685_1 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 427.0
HFD2_k127_788685_10 phosphatase activity K07025,K20862 - 3.1.3.102,3.1.3.104 0.0000000000000007338 89.0
HFD2_k127_788685_11 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.000000000000003607 85.0
HFD2_k127_788685_12 Copper-transporting ATPase 2 K17686 GO:0000041,GO:0000139,GO:0000166,GO:0002164,GO:0003674,GO:0003824,GO:0004008,GO:0005215,GO:0005375,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005770,GO:0005773,GO:0005774,GO:0005783,GO:0005794,GO:0005802,GO:0005886,GO:0005887,GO:0005911,GO:0005923,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0006873,GO:0006874,GO:0006875,GO:0006878,GO:0006882,GO:0007275,GO:0007589,GO:0007591,GO:0007593,GO:0007595,GO:0007623,GO:0008144,GO:0008150,GO:0008270,GO:0008324,GO:0009719,GO:0009725,GO:0009791,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0010042,GO:0010043,GO:0010243,GO:0012505,GO:0014070,GO:0014074,GO:0015075,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015677,GO:0015680,GO:0016020,GO:0016021,GO:0016323,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019725,GO:0019829,GO:0021700,GO:0022404,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030054,GO:0030554,GO:0030879,GO:0031090,GO:0031224,GO:0031226,GO:0031410,GO:0031982,GO:0031984,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032588,GO:0034220,GO:0035434,GO:0035639,GO:0036094,GO:0042221,GO:0042303,GO:0042335,GO:0042592,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043296,GO:0043434,GO:0043473,GO:0043492,GO:0043682,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044437,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0045177,GO:0046683,GO:0046688,GO:0046872,GO:0046873,GO:0046903,GO:0046907,GO:0046914,GO:0046915,GO:0046916,GO:0048066,GO:0048067,GO:0048085,GO:0048471,GO:0048511,GO:0048513,GO:0048731,GO:0048732,GO:0048856,GO:0048878,GO:0050801,GO:0050878,GO:0050896,GO:0051179,GO:0051208,GO:0051234,GO:0051235,GO:0051591,GO:0051641,GO:0051649,GO:0051716,GO:0055065,GO:0055069,GO:0055070,GO:0055074,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0060003,GO:0065007,GO:0065008,GO:0070160,GO:0070887,GO:0071241,GO:0071248,GO:0071280,GO:0071287,GO:0071944,GO:0072503,GO:0072507,GO:0090662,GO:0097159,GO:0097367,GO:0097708,GO:0098588,GO:0098590,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:0098791,GO:0098805,GO:0099131,GO:0099132,GO:1901265,GO:1901363,GO:1901652,GO:1901698,GO:1901700,GO:1990637 3.6.3.54 0.0000000642 61.0
HFD2_k127_788685_13 metalloendopeptidase activity K01283 - 3.4.15.1 0.0000093 58.0
HFD2_k127_788685_2 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 446.0
HFD2_k127_788685_3 Stage II sporulation protein K06381 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001039 300.0
HFD2_k127_788685_4 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000005471 272.0
HFD2_k127_788685_5 permease - - - 0.00000000000000000000000000000000000000000000000001093 195.0
HFD2_k127_788685_6 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.0000000000000000000000000000000000221 143.0
HFD2_k127_788685_7 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000002758 101.0
HFD2_k127_788685_9 - - - - 0.000000000000000535 91.0
HFD2_k127_7958652_0 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004673 421.0
HFD2_k127_7958652_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 377.0
HFD2_k127_7958652_2 histidine kinase A domain protein K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 362.0
HFD2_k127_7958652_3 GAF domain-containing protein K08968 - 1.8.4.14 0.000000000000000000000000000000000000000000000000000000000000001526 223.0
HFD2_k127_7958652_4 Poly A polymerase, head domain K00970 - 2.7.7.19 0.0000000000000000000000000000000000000000000000000000002603 221.0
HFD2_k127_7958652_5 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000004569 173.0
HFD2_k127_797529_0 Benzoyl-CoA reductase subunit K04114 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 346.0
HFD2_k127_797529_1 Benzoyl-CoA reductase subunit K04115 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007748 300.0
HFD2_k127_797529_2 tRNA pseudouridine synthase activity K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000002185 241.0
HFD2_k127_797529_3 reductase K00023,K00059 - 1.1.1.100,1.1.1.36 0.00000000000000000000000000000000000000000000000116 194.0
HFD2_k127_797529_4 Transcriptional regulator - - - 0.0000000005357 72.0
HFD2_k127_7978081_0 3-oxoacyl-[acyl-carrier-protein] synthase activity K09458,K18473 - 2.3.1.179,2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007257 616.0
HFD2_k127_7978081_1 protein histidine kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003767 528.0
HFD2_k127_7978081_2 Pyridoxal-dependent decarboxylase conserved domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004536 329.0
HFD2_k127_80472_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006097 593.0
HFD2_k127_80472_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 497.0
HFD2_k127_80472_2 Nickel-dependent hydrogenase - - - 0.00000000000000000003784 90.0
HFD2_k127_80472_3 Hydrogenase maturation protease K03605 - - 0.00000000000000002769 90.0
HFD2_k127_8061649_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168,K07479 GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.2 6.296e-270 856.0
HFD2_k127_8061649_1 Lysylphosphatidylglycerol synthase TM region K07027,K14205 - 2.3.2.3 1.54e-250 798.0
HFD2_k127_8061649_2 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 497.0
HFD2_k127_8061649_3 belongs to the thioredoxin family K05838 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 449.0
HFD2_k127_8061649_4 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000001189 265.0
HFD2_k127_8061649_5 TIGRFAM DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000355 243.0
HFD2_k127_8061649_6 Phage integrase, N-terminal SAM-like domain K03733,K04763 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000009244 243.0
HFD2_k127_8061649_7 Bacterial virulence protein (VirJ) - - - 0.0000000000000000000000000000000000000000000000000000000001562 214.0
HFD2_k127_8061649_8 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000002037 159.0
HFD2_k127_8061649_9 COG0457 FOG TPR repeat - - - 0.00000000001057 78.0
HFD2_k127_8068548_0 phosphoserine phosphatase activity K07711 - 2.7.13.3 0.0000000000000000000000000000000000000000000001155 186.0
HFD2_k127_8068548_1 Na+/Pi-cotransporter - - - 0.000000000000006313 78.0
HFD2_k127_8068548_2 nuclease subunit A K16898 - 3.6.4.12 0.00000000000003214 81.0
HFD2_k127_8071857_0 amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001253 260.0
HFD2_k127_8071857_1 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000001698 128.0
HFD2_k127_8081725_0 Amino acid permease - - - 6.914e-206 660.0
HFD2_k127_8081725_1 TIGRFAM lysine 2,3-aminomutase YodO family protein K01843 - 5.4.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003593 463.0
HFD2_k127_8081725_2 Aminotransferase class-III K15372 - 2.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 371.0
HFD2_k127_8081725_3 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000002239 275.0
HFD2_k127_8081725_4 XdhC and CoxI family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002305 261.0
HFD2_k127_8081725_5 ATP-grasp domain K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000718 255.0
HFD2_k127_8081725_6 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.0000000000000000000000000000000000000003884 162.0
HFD2_k127_8081725_7 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000002999 147.0
HFD2_k127_8081725_8 ABC transporter K01990 - - 0.00000000000000000000000000002492 135.0
HFD2_k127_8081725_9 HEPN domain - - - 0.000000000000000004738 91.0
HFD2_k127_8102198_0 Required for morphogenesis under gluconeogenic growth conditions - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 327.0
HFD2_k127_8102198_1 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005917 311.0
HFD2_k127_8102198_2 Deoxynucleoside kinase K15518 - 2.7.1.113 0.000000000000000000000000000000000000000000000000000000000000000000004241 240.0
HFD2_k127_8102198_3 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000000000000000000000000000000313 183.0
HFD2_k127_8102198_4 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950,K17488 - 2.7.6.3,3.5.4.39 0.0000000000000000000000000000000006061 138.0
HFD2_k127_8102198_5 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000003016 112.0
HFD2_k127_8102198_6 Tetratricopeptide repeat - - - 0.0001997 51.0
HFD2_k127_8106237_0 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000593 283.0
HFD2_k127_8106237_1 Protein export membrane protein K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000001639 265.0
HFD2_k127_8106237_2 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000002165 219.0
HFD2_k127_8106237_3 COGs COG3328 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000000001028 169.0
HFD2_k127_8106237_4 PFAM Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000002236 124.0
HFD2_k127_8106237_5 Periplasmic or secreted lipoprotein K04065 GO:0005575,GO:0005623,GO:0006457,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0009628,GO:0009987,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0050896,GO:0061077 - 0.00000000000000003004 89.0
HFD2_k127_8106237_6 Methyltransferase domain - - - 0.0000000000000001721 81.0
HFD2_k127_8106237_7 SMART Transport-associated and nodulation region K04065 - - 0.000000000001548 81.0
HFD2_k127_8115222_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 7.765e-200 646.0
HFD2_k127_8115222_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000003373 203.0
HFD2_k127_8115222_2 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.00000000000000000000001823 110.0
HFD2_k127_8131613_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 395.0
HFD2_k127_8131613_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000001113 246.0
HFD2_k127_8131613_2 oligosaccharyl transferase activity K07151 - 2.4.99.18 0.00000000000000000000000000000000000000000002794 182.0
HFD2_k127_8131613_3 Cytochrome c assembly protein - - - 0.00000000000000000000000000000000001109 150.0
HFD2_k127_8131613_4 Uroporphyrinogen-III synthase K01719,K13542 - 2.1.1.107,4.2.1.75 0.0000000000000133 82.0
HFD2_k127_8141512_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 5.572e-253 796.0
HFD2_k127_8141512_1 Nucleotidyl transferase K04042,K11528 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005601 328.0
HFD2_k127_816186_0 Rubrerythrin K22405 - 1.6.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006466 528.0
HFD2_k127_816186_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006581 296.0
HFD2_k127_816186_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005087 294.0
HFD2_k127_816186_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000001365 238.0
HFD2_k127_816186_4 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.00005906 52.0
HFD2_k127_8166633_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702,K08999 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009380,GO:0009628,GO:0032991,GO:0042802,GO:0044424,GO:0044464,GO:0050896,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 4.473e-276 871.0
HFD2_k127_8166633_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 520.0
HFD2_k127_8166633_2 Transglycosylase K05366 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0008955,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042546,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008275 475.0
HFD2_k127_8166633_3 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000009893 218.0
HFD2_k127_8166633_4 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00002397 57.0
HFD2_k127_8181857_0 Cation efflux family K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001376 273.0
HFD2_k127_8181857_1 Heat shock protein DnaJ domain protein - - - 0.0000000000000000000000000000000000000000000000004036 198.0
HFD2_k127_8181857_2 Domain of unknown function (DUF296) K06934 - - 0.00000000000000002336 96.0
HFD2_k127_8202047_0 O-Antigen ligase K02847 - - 0.000000000000000000000000000000000000441 158.0
HFD2_k127_8202047_1 Belongs to the peptidase S8 family - - - 0.00001712 55.0
HFD2_k127_8202047_2 cellulose synthase operon C domain protein K20543 - - 0.0002798 54.0
HFD2_k127_8202047_3 Parallel beta-helix repeats - - - 0.0004386 50.0
HFD2_k127_8212587_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 4.693e-291 914.0
HFD2_k127_8212587_1 Belongs to the PdxS SNZ family K06215 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004162 413.0
HFD2_k127_8212587_10 converts alpha-aldose to the beta-anomer - - - 0.00000000000000000000000000000000000373 148.0
HFD2_k127_8212587_11 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.00000000000000000000000000001293 132.0
HFD2_k127_8212587_12 Peptidylprolyl isomerase K03770 - 5.2.1.8 0.000000000000000000000001953 108.0
HFD2_k127_8212587_13 Outer membrane lipoprotein - - - 0.00000000000000000002965 100.0
HFD2_k127_8212587_14 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000001835 74.0
HFD2_k127_8212587_15 Tetratricopeptide repeat - - - 0.000000000001241 79.0
HFD2_k127_8212587_16 TIGRFAM TonB family K03832 - - 0.00000000001196 77.0
HFD2_k127_8212587_17 Chaperone dnaJ 6 K09529 GO:0003674,GO:0005488,GO:0005515,GO:0030544,GO:0031072 - 0.0005 48.0
HFD2_k127_8212587_2 Alanine-glyoxylate amino-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004452 379.0
HFD2_k127_8212587_3 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 383.0
HFD2_k127_8212587_4 SMART PUA domain containing protein K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005332 364.0
HFD2_k127_8212587_5 TolB amino-terminal domain K03641 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019534,GO:0019904,GO:0022857,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901998 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006666 286.0
HFD2_k127_8212587_6 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000837 203.0
HFD2_k127_8212587_7 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.000000000000000000000000000000000000000000008217 176.0
HFD2_k127_8212587_8 PFAM MotA TolQ ExbB proton channel K03562 - - 0.00000000000000000000000000000000000000000001272 173.0
HFD2_k127_8212587_9 PFAM OmpA MotB domain protein K03640 - - 0.00000000000000000000000000000000000001579 151.0
HFD2_k127_8216898_0 peptidase K07386 - - 5.519e-297 925.0
HFD2_k127_8216898_1 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003897 334.0
HFD2_k127_8216898_2 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000005056 262.0
HFD2_k127_8216898_3 Uncharacterized protein family UPF0016 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001719 235.0
HFD2_k127_8216898_4 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000000000000000000000000000000000000000000001445 220.0
HFD2_k127_8216898_5 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000002195 228.0
HFD2_k127_8216898_6 MarR family transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000001071 194.0
HFD2_k127_8216898_7 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000001604 108.0
HFD2_k127_8216898_8 - - - - 0.000000000000000001224 98.0
HFD2_k127_8216898_9 - - - - 0.0000003758 55.0
HFD2_k127_8255254_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1206.0
HFD2_k127_8255254_1 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000824 397.0
HFD2_k127_8255254_11 Redoxin K03564 - 1.11.1.15 0.00000000001561 76.0
HFD2_k127_8255254_12 PspC domain K03973 - - 0.00000000006415 70.0
HFD2_k127_8255254_13 membrane - - - 0.000000007051 67.0
HFD2_k127_8255254_14 RelA SpoT domain protein - - - 0.0000001559 66.0
HFD2_k127_8255254_15 peptidase - - - 0.0003641 54.0
HFD2_k127_8255254_2 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 317.0
HFD2_k127_8255254_3 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008958 313.0
HFD2_k127_8255254_4 NnrS protein K07234 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001992 291.0
HFD2_k127_8255254_5 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000263 256.0
HFD2_k127_8255254_6 Domain of unknown function (DUF4336) - - - 0.000000000000000000000000000001666 132.0
HFD2_k127_8255254_7 COG2346, Truncated hemoglobins K06886 - - 0.00000000000000000000000000004274 122.0
HFD2_k127_8255254_8 - - - - 0.000000000000000000000000003222 118.0
HFD2_k127_8255254_9 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000002594 110.0
HFD2_k127_827979_0 Oligoendopeptidase f - - - 1.74e-289 927.0
HFD2_k127_827979_1 Zinc carboxypeptidase K14054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001253 274.0
HFD2_k127_8282899_0 Putative metal-binding motif - - - 0.00000000000000000000001122 117.0
HFD2_k127_8282899_1 DNA-binding transcriptional activator of the SARP family - - - 0.00000000004145 74.0
HFD2_k127_8325255_0 dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0015949,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000131 219.0
HFD2_k127_8325255_1 integral membrane protein - - - 0.00000002066 61.0
HFD2_k127_8338419_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1080.0
HFD2_k127_8338419_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 5.396e-283 878.0
HFD2_k127_8338419_10 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000001107 138.0
HFD2_k127_8338419_11 Outer membrane efflux protein - - - 0.0000000000000000000000000002951 130.0
HFD2_k127_8338419_12 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.000000000000000000000713 107.0
HFD2_k127_8338419_2 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 468.0
HFD2_k127_8338419_3 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 391.0
HFD2_k127_8338419_4 Belongs to the peptidase M50B family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000277 249.0
HFD2_k127_8338419_5 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000005893 250.0
HFD2_k127_8338419_6 activator of Hsp90 ATPase 1 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000003797 222.0
HFD2_k127_8338419_7 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.000000000000000000000000000000000000000000000000000000584 196.0
HFD2_k127_8338419_8 - - - - 0.0000000000000000000000000000000000000003928 155.0
HFD2_k127_8338419_9 HlyD family secretion protein - - - 0.00000000000000000000000000000000004614 148.0
HFD2_k127_8391007_0 COG1131 ABC-type multidrug transport system, ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002597 281.0
HFD2_k127_8391007_1 Alpha amylase, catalytic domain K06044 - 5.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000008648 227.0
HFD2_k127_8391007_2 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000002492 124.0
HFD2_k127_8391007_3 ABC-2 family transporter protein K01990,K01992 - - 0.0000000006307 72.0
HFD2_k127_8394645_0 Belongs to the peptidase M16 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005643 434.0
HFD2_k127_8394645_1 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000001422 214.0
HFD2_k127_8394645_2 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.0000000000000000000000000000000000000000000000002904 179.0
HFD2_k127_8394645_3 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000626 116.0
HFD2_k127_8394645_4 - - - - 0.0005459 51.0
HFD2_k127_8401952_0 Belongs to the GHMP kinase family K00849 - 2.7.1.6 0.000000000000000000000000000000000000000000000000001854 194.0
HFD2_k127_8401952_1 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.0003034 50.0
HFD2_k127_8407599_0 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000007987 279.0
HFD2_k127_8407599_1 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000005012 252.0
HFD2_k127_8407599_2 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000000000000000000000000000000005431 182.0
HFD2_k127_8407599_3 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.00000000000000000000008086 109.0
HFD2_k127_8412431_0 Chemotaxis K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004588 584.0
HFD2_k127_8413031_0 non-ribosomal peptide synthetase - - - 3.21e-254 824.0
HFD2_k127_8413031_1 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K00836,K06136,K06137,K06138 GO:0005575,GO:0005576 1.3.3.11,2.6.1.76 0.000000000000000000000000000000000000000000000000000000000000000001532 237.0
HFD2_k127_8413031_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000005292 192.0
HFD2_k127_8429624_0 Dehydrogenase E1 component K11381 - 1.2.4.4 2.84e-272 873.0
HFD2_k127_8429624_1 Aminotransferase class-V K01556 - 3.7.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004682 427.0
HFD2_k127_8429624_2 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006084,GO:0006139,GO:0006163,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009117,GO:0009150,GO:0009259,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019442,GO:0019637,GO:0019693,GO:0019752,GO:0020037,GO:0022607,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043603,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051186,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0072521,GO:0097159,GO:1901135,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11 0.00000000000000000000000000000000000000000000000000000000000000002441 234.0
HFD2_k127_8429624_3 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000188 214.0
HFD2_k127_8429624_4 Dehydrogenase E1 component K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000001382 188.0
HFD2_k127_8429624_5 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000542 168.0
HFD2_k127_8429624_6 Redoxin - - - 0.000000000000000000000000006744 125.0
HFD2_k127_844757_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002858 265.0
HFD2_k127_844757_1 HlyD family secretion protein K02005 - - 0.00000000000000000000000000000000000000000001736 177.0
HFD2_k127_844757_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000001238 75.0
HFD2_k127_8448611_0 positive regulation of growth rate - - - 0.00000000000000000000000000000000000008009 160.0
HFD2_k127_8448611_1 Methyltransferase K08316 - 2.1.1.171 0.0000000000000000000000000000000000003399 148.0
HFD2_k127_8448611_2 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000002212 81.0
HFD2_k127_8461854_0 phosphatase activity - - - 1.294e-205 659.0
HFD2_k127_8461854_1 Zinc-binding alcohol dehydrogenase family protein K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007145 392.0
HFD2_k127_8461854_2 DJ-1/PfpI family K05520 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000002978 190.0
HFD2_k127_8461854_3 Stress-responsive transcriptional regulator - - - 0.000000000000000007832 84.0
HFD2_k127_8528957_0 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 357.0
HFD2_k127_8528957_1 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000001282 219.0
HFD2_k127_8528957_2 protein trimerization - - - 0.0000000000000000000000000000003237 128.0
HFD2_k127_8528957_3 Flavin and coenzyme A sequestration protein dodecin K09165 - - 0.000000000000000000000003854 115.0
HFD2_k127_8565335_0 Cytochrome c554 and c-prime - - - 2.036e-268 861.0
HFD2_k127_8565335_1 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 591.0
HFD2_k127_8565335_2 response regulator K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000002222 250.0
HFD2_k127_8565335_3 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000719 109.0
HFD2_k127_8565335_4 peptidyl-prolyl isomerase K01802,K03769 - 5.2.1.8 0.00000000000000001249 91.0
HFD2_k127_8667959_0 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000376 336.0
HFD2_k127_8667959_1 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004001 258.0
HFD2_k127_8667959_2 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000169 199.0
HFD2_k127_8667959_3 arylsulfatase activity - - - 0.000000000000000000000000000000000000001859 164.0
HFD2_k127_8667959_4 Lipid A Biosynthesis N-terminal domain - - - 0.00000000000000000000000000000004175 127.0
HFD2_k127_8667959_5 HAD-hyrolase-like - - - 0.00000000000000000000000000001653 135.0
HFD2_k127_8674497_0 Belongs to the DapA family K01714,K22397 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016830,GO:0016832,GO:0019520,GO:0019752,GO:0032787,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046395,GO:0047440,GO:0071704,GO:0072329,GO:1901575 4.1.2.28,4.3.3.7 0.00000000000000000000000000000000000000000000000000001263 199.0
HFD2_k127_8674497_1 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000002384 186.0
HFD2_k127_8674497_2 - - - - 0.00000000000129 77.0
HFD2_k127_8675054_0 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005205 502.0
HFD2_k127_8675054_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 434.0
HFD2_k127_8675054_2 Penicillin-binding protein 2 K05515 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 0.00000000000000000000000163 118.0
HFD2_k127_8697690_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1079.0
HFD2_k127_8697690_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 4.842e-210 664.0
HFD2_k127_8697690_2 PFAM Cytochrome c oxidase, subunit I K04561 - 1.7.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 598.0
HFD2_k127_8697690_3 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 488.0
HFD2_k127_8697690_4 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 424.0
HFD2_k127_8697690_5 SAICAR synthetase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 378.0
HFD2_k127_8697690_6 PFAM Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000001764 214.0
HFD2_k127_8697690_7 cytochrome c K02305 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000004984 188.0
HFD2_k127_8697690_8 PFAM peptidase - - - 0.0000000000000000000000000000000000000000124 164.0
HFD2_k127_8697690_9 electron transfer activity - - - 0.00000000000000006554 87.0
HFD2_k127_8700731_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 7.896e-230 730.0
HFD2_k127_8700731_1 PFAM Pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 2.605e-195 623.0
HFD2_k127_8700731_2 Rhomboid family K19225 - 3.4.21.105 0.0000000000000000000000000000000000004832 161.0
HFD2_k127_8731069_0 PFAM MMPL family K07003 - - 4.991e-211 681.0
HFD2_k127_8731069_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000983 529.0
HFD2_k127_8731069_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 GO:0000162,GO:0003674,GO:0003824,GO:0004834,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000002513 259.0
HFD2_k127_8731069_3 Methylpurine-DNA glycosylase (MPG) K03652 - 3.2.2.21 0.000000000000000000000000000000000000000000000000002424 186.0
HFD2_k127_8731069_4 - - - - 0.000000000000000000004979 95.0
HFD2_k127_8731069_5 COG1520 FOG WD40-like repeat - - - 0.0000000000000002275 92.0
HFD2_k127_897440_0 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003001 557.0
HFD2_k127_897440_1 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 509.0
HFD2_k127_897440_2 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 361.0
HFD2_k127_897440_3 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000001348 187.0
HFD2_k127_946694_0 Ring hydroxylating alpha subunit (catalytic domain) K00479,K00499 - 1.14.15.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005727 339.0
HFD2_k127_946694_1 PFAM Zinc carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 349.0
HFD2_k127_946694_2 Transposase IS116 IS110 IS902 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 318.0
HFD2_k127_946694_3 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000000000000000000000005781 218.0
HFD2_k127_946694_4 Tetratricopeptide repeat - - - 0.0000000000000002985 94.0
HFD2_k127_964161_0 Peptidase U62 modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008032 412.0
HFD2_k127_964161_1 PAS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 316.0
HFD2_k127_964161_2 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008411 295.0
HFD2_k127_964161_3 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001485 252.0
HFD2_k127_964161_4 PFAM sigma-54 factor interaction domain-containing protein, response regulator receiver, helix-turn-helix Fis-type K07714 - - 0.00000000000000000000000000000000000000000000009956 190.0
HFD2_k127_964161_5 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000007612 143.0
HFD2_k127_964161_6 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000007527 71.0