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Overview

ID MAG01659
Name HFD2_bin.51
Sample SMP0044
Taxonomy
Kingdom Bacteria
Phylum Myxococcota
Class Myxococcia
Order Myxococcales
Family Anaeromyxobacteraceae
Genus DATBLK01
Species
Assembly information
Completeness (%) 99.62
Contamination (%) 6.69
GC content (%) 73.0
N50 (bp) 43,853
Genome size (bp) 4,011,638

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3301

Gene name Description KEGG GOs EC E-value Score Sequence
HFD2_k127_1009155_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 6.326e-282 899.0
HFD2_k127_1009155_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 3.903e-258 801.0
HFD2_k127_1009155_10 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008502 525.0
HFD2_k127_1009155_11 VWA domain containing CoxE-like protein K07161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 505.0
HFD2_k127_1009155_12 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003474 489.0
HFD2_k127_1009155_13 Tfp pilus assembly protein FimV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003702 417.0
HFD2_k127_1009155_14 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K02056,K05776,K10441,K10539,K10542,K10545,K10548 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 436.0
HFD2_k127_1009155_15 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 398.0
HFD2_k127_1009155_16 Belongs to the bacterial solute-binding protein 9 family K02077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005707 386.0
HFD2_k127_1009155_17 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 408.0
HFD2_k127_1009155_18 Acyl CoA acetate 3-ketoacid CoA transferase beta subunit K01029 - 2.8.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000765 375.0
HFD2_k127_1009155_19 Asparaginase K13051 - 3.4.19.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 364.0
HFD2_k127_1009155_2 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 1.394e-230 720.0
HFD2_k127_1009155_21 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01028 - 2.8.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 360.0
HFD2_k127_1009155_22 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005543 329.0
HFD2_k127_1009155_23 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 319.0
HFD2_k127_1009155_24 ABC 3 transport family K09816 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 310.0
HFD2_k127_1009155_25 Putative zinc-finger - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 292.0
HFD2_k127_1009155_26 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 286.0
HFD2_k127_1009155_27 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 285.0
HFD2_k127_1009155_28 PFAM ABC transporter K09817 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003061 291.0
HFD2_k127_1009155_29 HemY protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003244 278.0
HFD2_k127_1009155_3 Belongs to the thiolase family K00626 - 2.3.1.9 5.503e-194 612.0
HFD2_k127_1009155_30 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001163 260.0
HFD2_k127_1009155_31 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000000000000000004236 220.0
HFD2_k127_1009155_32 PHP domain protein - - - 0.00000000000000000000000000000000000000000000000001319 207.0
HFD2_k127_1009155_33 - - - - 0.000000000000000000000000000000000000000000000001624 200.0
HFD2_k127_1009155_34 SCP-2 sterol transfer family - - - 0.0000000000000000000000000000000000000000000002094 170.0
HFD2_k127_1009155_35 PilZ domain K02676 - - 0.000000000000000000000000000000000000000001676 162.0
HFD2_k127_1009155_36 Endoribonuclease L-PSP K04782 - 4.2.99.21 0.000000000000000000000000000000000000000001712 179.0
HFD2_k127_1009155_37 PFAM Cyclic nucleotide-binding - - - 0.000000000000000000000000000000000000000002386 169.0
HFD2_k127_1009155_38 cell adhesion involved in biofilm formation - - - 0.000000000000000000000000000000000000145 165.0
HFD2_k127_1009155_39 - K07018 - - 0.00000000000000000000000005545 115.0
HFD2_k127_1009155_4 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008711 623.0
HFD2_k127_1009155_40 toxin-antitoxin pair type II binding - - - 0.0000000000000000007453 89.0
HFD2_k127_1009155_41 Uncharacterised protein family (UPF0158) - - - 0.0000000000199 73.0
HFD2_k127_1009155_43 - - - - 0.00000002808 68.0
HFD2_k127_1009155_44 - - - - 0.00000002999 59.0
HFD2_k127_1009155_45 Protein of unknown function (DUF433) - - - 0.00008661 46.0
HFD2_k127_1009155_46 response to nickel cation - GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0008150,GO:0040008,GO:0045926,GO:0045927,GO:0048518,GO:0048519,GO:0050789,GO:0065007,GO:0097159,GO:1901363 - 0.0009538 45.0
HFD2_k127_1009155_5 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 623.0
HFD2_k127_1009155_6 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007202 581.0
HFD2_k127_1009155_7 CoA-transferase family III K01796 - 5.1.99.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 553.0
HFD2_k127_1009155_8 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 571.0
HFD2_k127_1009155_9 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007055 543.0
HFD2_k127_1029874_0 Peptidogalycan biosysnthesis/recognition K09919 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008251 394.0
HFD2_k127_1029874_1 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003871 378.0
HFD2_k127_1029874_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 347.0
HFD2_k127_1029874_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002295 280.0
HFD2_k127_1029874_4 Peptidogalycan biosysnthesis/recognition K09919 - - 0.0000000000000000000000000000001823 124.0
HFD2_k127_1044824_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 588.0
HFD2_k127_1044824_1 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000672 428.0
HFD2_k127_1044824_2 phosphorelay signal transduction system - - - 0.0000000000000000000000001707 111.0
HFD2_k127_104864_0 Serine Threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 412.0
HFD2_k127_1049790_0 zinc ion binding K06204 - - 0.000000000000000000000000000007139 134.0
HFD2_k127_1049790_1 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.0000000001002 72.0
HFD2_k127_1049790_2 response regulator K02481,K07713 - - 0.0000000002353 61.0
HFD2_k127_1131757_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008642 430.0
HFD2_k127_1131757_2 Heat shock 70 kDa protein K04043 - - 0.0000000003732 64.0
HFD2_k127_113747_0 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007891 437.0
HFD2_k127_113747_1 Protein of unknown function (DUF1015) - - - 0.00000000000000000002656 90.0
HFD2_k127_113747_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000005414 95.0
HFD2_k127_113747_3 response regulator, receiver - - - 0.000001686 59.0
HFD2_k127_1140199_0 Sulfate ABC transporter, permease K02047 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009823 379.0
HFD2_k127_1140199_1 Binding-protein-dependent transport system inner membrane component K02046,K15496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 363.0
HFD2_k127_1140199_2 COG1613 ABC-type sulfate transport system, periplasmic component K02048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003552 255.0
HFD2_k127_1140199_3 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0006810,GO:0006811,GO:0006820,GO:0008144,GO:0008150,GO:0008272,GO:0008509,GO:0015075,GO:0015103,GO:0015116,GO:0015318,GO:0015399,GO:0015405,GO:0015419,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0072348,GO:0097159,GO:0097367,GO:0098656,GO:0098660,GO:0098661,GO:0099133,GO:1901265,GO:1901363,GO:1901682,GO:1902358 3.6.3.25 0.000000000000000000000000000000000006724 156.0
HFD2_k127_1145278_0 SMART helicase c2 K03722 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 527.0
HFD2_k127_1145278_1 Small GTP-binding protein K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005932 383.0
HFD2_k127_1152275_0 Ferric reductase like transmembrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 330.0
HFD2_k127_1152275_1 Peptidase family M20/M25/M40 K12941 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009109,GO:0009111,GO:0009397,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0019439,GO:0019752,GO:0034641,GO:0042219,GO:0042365,GO:0042558,GO:0042560,GO:0042737,GO:0043436,GO:0043603,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046655,GO:0046657,GO:0046700,GO:0046982,GO:0046983,GO:0051186,GO:0051187,GO:0071704,GO:0071713,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000002371 86.0
HFD2_k127_1152275_2 Peptidase dimerisation domain K12941,K21613 - - 0.000000000001482 70.0
HFD2_k127_1229756_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 0.0 1021.0
HFD2_k127_1229756_1 protein conserved in bacteria K11904 - - 2.314e-230 742.0
HFD2_k127_1229756_10 Patatin-like phospholipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006104 505.0
HFD2_k127_1229756_11 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 436.0
HFD2_k127_1229756_12 Involved in the tonB-independent uptake of proteins K03641,K10117 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009662 429.0
HFD2_k127_1229756_13 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000048 426.0
HFD2_k127_1229756_14 TIGRFAM decaheme c-type cytochrome, OmcA MtrC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 429.0
HFD2_k127_1229756_15 Uncharacterized protein conserved in bacteria (DUF2169) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007285 394.0
HFD2_k127_1229756_16 COG1064 Zn-dependent alcohol K12957 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 354.0
HFD2_k127_1229756_17 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 349.0
HFD2_k127_1229756_18 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006419 350.0
HFD2_k127_1229756_19 cytochrome c K02305 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007286 332.0
HFD2_k127_1229756_2 PFAM Cytochrome c oxidase, subunit I K04561 - 1.7.2.5 9.715e-228 724.0
HFD2_k127_1229756_20 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 321.0
HFD2_k127_1229756_21 deoxyhypusine monooxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002056 271.0
HFD2_k127_1229756_22 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006378 267.0
HFD2_k127_1229756_23 beta-ketoacyl-acyl-carrier-protein synthase II activity K00647 - 2.3.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000008462 274.0
HFD2_k127_1229756_24 Domain of unknown function (DUF4037) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000271 254.0
HFD2_k127_1229756_25 Domain of unknown function (DUF4150) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000964 233.0
HFD2_k127_1229756_26 PFAM regulatory protein TetR - - - 0.000000000000000000000000000000000000000000000000000000000000003088 224.0
HFD2_k127_1229756_27 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000000000000002548 215.0
HFD2_k127_1229756_28 ADP binding - - - 0.00000000000000000000000000000000000000000000000000000001735 221.0
HFD2_k127_1229756_29 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000001675 196.0
HFD2_k127_1229756_3 DNA topoisomerase VI subunit A K03166 - 5.99.1.3 1.729e-205 644.0
HFD2_k127_1229756_31 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.000000000000000000000000000000000000000000000008258 184.0
HFD2_k127_1229756_32 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000000006645 186.0
HFD2_k127_1229756_33 PFAM Glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.00000000000000000000000000000000000000002147 160.0
HFD2_k127_1229756_34 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000002283 148.0
HFD2_k127_1229756_35 - - - - 0.000000000000000000000000000000000001029 158.0
HFD2_k127_1229756_36 - - - - 0.000000000000000000000000000000004333 135.0
HFD2_k127_1229756_37 Domain of unknown function(DUF2779) - - - 0.00000000000000000000000000000007974 129.0
HFD2_k127_1229756_38 - - - - 0.0000000000000000000000000000126 134.0
HFD2_k127_1229756_39 Predicted membrane protein (DUF2339) - - - 0.00000000000000000000000000006995 135.0
HFD2_k127_1229756_4 PFAM Polysulphide reductase, NrfD - - - 5.537e-198 640.0
HFD2_k127_1229756_40 Immunity protein 49 - - - 0.0000000000000000000000000001809 133.0
HFD2_k127_1229756_41 oxygen carrier activity K07216 - - 0.00000000000000000000000003684 113.0
HFD2_k127_1229756_42 TIGRFAM cytochrome C family protein - - - 0.0000000000000000000000559 117.0
HFD2_k127_1229756_43 Protein of unknown function (DUF455) K11529 - 2.7.1.165 0.000000000000003534 88.0
HFD2_k127_1229756_44 Protein of unknown function (DUF455) K11529 - 2.7.1.165 0.0000000000001222 81.0
HFD2_k127_1229756_45 asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00000000000107 81.0
HFD2_k127_1229756_46 Redoxin K03564 - 1.11.1.15 0.000000000001357 68.0
HFD2_k127_1229756_48 Domain of unknown function (DUF4124) - - - 0.00000000002001 75.0
HFD2_k127_1229756_49 Protein of unknown function (DUF455) - - - 0.00000000008676 72.0
HFD2_k127_1229756_5 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 597.0
HFD2_k127_1229756_51 Alpha/beta hydrolase family - - - 0.000004772 53.0
HFD2_k127_1229756_52 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.00005261 56.0
HFD2_k127_1229756_53 Peptidase S24-like - - - 0.0002601 51.0
HFD2_k127_1229756_6 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 594.0
HFD2_k127_1229756_7 Efflux ABC transporter, permease ATP-binding protein K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 591.0
HFD2_k127_1229756_8 Phage late control gene D protein (GPD) K11904 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000981 521.0
HFD2_k127_1229756_9 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 477.0
HFD2_k127_1285098_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 462.0
HFD2_k127_1285098_1 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000002838 270.0
HFD2_k127_1285098_2 Prokaryotic N-terminal methylation motif K02650 - - 0.000000000000000000002393 95.0
HFD2_k127_131025_0 benzoyl-CoA oxygenase K15512 - 1.14.13.208 1.03e-234 741.0
HFD2_k127_131025_1 Enoyl-CoA hydratase/isomerase K15513 - 4.1.2.44 3.403e-231 731.0
HFD2_k127_131025_10 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 358.0
HFD2_k127_131025_11 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 346.0
HFD2_k127_131025_12 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 360.0
HFD2_k127_131025_13 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 315.0
HFD2_k127_131025_14 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 312.0
HFD2_k127_131025_15 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009142 309.0
HFD2_k127_131025_16 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 291.0
HFD2_k127_131025_17 TIGRFAM CoA-substrate-specific enzyme activase - - - 0.00000000000000000000000000000000000000000000000000000007083 224.0
HFD2_k127_131025_18 Thioesterase-like superfamily K01075 - 3.1.2.23 0.000000000000000000000000000000000000000000001846 170.0
HFD2_k127_131025_19 TIGRFAM CoA-substrate-specific enzyme activase - - - 0.000000000000000000000000000000000008397 157.0
HFD2_k127_131025_2 AMP-binding enzyme C-terminal domain K04110 - 6.2.1.25 2.93e-225 714.0
HFD2_k127_131025_20 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000001857 64.0
HFD2_k127_131025_3 Aldehyde dehydrogenase family K02618,K15514 - 1.2.1.77,1.2.1.91,3.3.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006007 597.0
HFD2_k127_131025_4 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009455 594.0
HFD2_k127_131025_5 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006902 561.0
HFD2_k127_131025_6 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 505.0
HFD2_k127_131025_7 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 419.0
HFD2_k127_131025_8 Amino acid amide ABC transporter substrate-binding protein, HAAT family K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004733 392.0
HFD2_k127_131025_9 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005353 360.0
HFD2_k127_134429_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0 1393.0
HFD2_k127_134429_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 2.359e-240 746.0
HFD2_k127_134429_10 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 535.0
HFD2_k127_134429_11 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 458.0
HFD2_k127_134429_12 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 458.0
HFD2_k127_134429_13 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 439.0
HFD2_k127_134429_14 TIGRFAM cytochrome C family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003919 418.0
HFD2_k127_134429_15 Enoyl-(Acyl carrier protein) reductase K13775 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007724 400.0
HFD2_k127_134429_16 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004173 405.0
HFD2_k127_134429_18 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000001597 285.0
HFD2_k127_134429_19 Cell division protein FtsQ K03589 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000508 253.0
HFD2_k127_134429_2 Belongs to the MurCDEF family K01924 - 6.3.2.8 7.609e-223 719.0
HFD2_k127_134429_20 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001537 265.0
HFD2_k127_134429_21 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000003246 229.0
HFD2_k127_134429_23 TPR repeat - - - 0.0000000000000000000000000000000000000000008901 178.0
HFD2_k127_134429_25 TPR repeat - - - 0.00000000000000000000003578 111.0
HFD2_k127_134429_26 PFAM CBS domain containing protein - - - 0.00000000000000003622 87.0
HFD2_k127_134429_27 cell division K03586 GO:0000003,GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0019954,GO:0022402,GO:0022414,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0043093,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944 - 0.000000000000001665 89.0
HFD2_k127_134429_28 TIGRFAM cytochrome C family protein - - - 0.00000000000001112 84.0
HFD2_k127_134429_3 penicillin-binding protein K03587 - 3.4.16.4 4.249e-205 664.0
HFD2_k127_134429_4 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 613.0
HFD2_k127_134429_5 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 608.0
HFD2_k127_134429_6 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 576.0
HFD2_k127_134429_7 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 584.0
HFD2_k127_134429_8 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000388 540.0
HFD2_k127_134429_9 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006871 548.0
HFD2_k127_136102_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0 1417.0
HFD2_k127_136102_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.0 1146.0
HFD2_k127_136102_10 Bacterial regulatory protein, Fis family K13599 - - 6.158e-238 773.0
HFD2_k127_136102_11 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 4.701e-235 733.0
HFD2_k127_136102_12 ABC-type transport system involved in lipoprotein release permease component K09808 - - 2.966e-227 721.0
HFD2_k127_136102_13 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 3.186e-206 674.0
HFD2_k127_136102_14 Patatin-like phospholipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 615.0
HFD2_k127_136102_15 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 621.0
HFD2_k127_136102_16 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 597.0
HFD2_k127_136102_17 Signal transduction histidine kinase K13598 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009635 595.0
HFD2_k127_136102_18 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 546.0
HFD2_k127_136102_19 Surface antigen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 545.0
HFD2_k127_136102_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0 1072.0
HFD2_k127_136102_20 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007107 549.0
HFD2_k127_136102_21 PFAM phosphoesterase, RecJ domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 500.0
HFD2_k127_136102_22 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 483.0
HFD2_k127_136102_23 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 471.0
HFD2_k127_136102_24 Aminotransferase, class V K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 480.0
HFD2_k127_136102_25 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 468.0
HFD2_k127_136102_26 PFAM Metallophosphoesterase K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 438.0
HFD2_k127_136102_27 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 447.0
HFD2_k127_136102_28 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 411.0
HFD2_k127_136102_29 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006948 409.0
HFD2_k127_136102_3 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 3.534e-316 988.0
HFD2_k127_136102_30 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008018 374.0
HFD2_k127_136102_31 Protein of unknown function (DUF1009) K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 375.0
HFD2_k127_136102_32 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 361.0
HFD2_k127_136102_33 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 350.0
HFD2_k127_136102_34 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005155 328.0
HFD2_k127_136102_35 Fic/DOC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 318.0
HFD2_k127_136102_36 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 323.0
HFD2_k127_136102_37 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000421 286.0
HFD2_k127_136102_38 Domain of unknown function (DUF4912) K09942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000991 289.0
HFD2_k127_136102_39 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000682 244.0
HFD2_k127_136102_4 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 2.027e-315 979.0
HFD2_k127_136102_40 regulator K07773 - - 0.000000000000000000000000000000000000000000000000000000001149 230.0
HFD2_k127_136102_41 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000004432 198.0
HFD2_k127_136102_42 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.0000000000000000000000000000000000000000000000000033 209.0
HFD2_k127_136102_43 Outer membrane protein (OmpH-like) K06142 - - 0.00000000000000000000000000000000000000000000005978 192.0
HFD2_k127_136102_44 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000003383 177.0
HFD2_k127_136102_45 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000000000000000000002265 173.0
HFD2_k127_136102_46 Protein of unknown function (DUF503) K09764 - - 0.000000000000000000000000000000000000000000005162 168.0
HFD2_k127_136102_47 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000008262 163.0
HFD2_k127_136102_48 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.000000000000000000000000000000000000000001224 162.0
HFD2_k127_136102_5 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 4.456e-307 952.0
HFD2_k127_136102_50 Belongs to the UPF0235 family K09131 - - 0.0000000000000000000000001776 119.0
HFD2_k127_136102_51 Phage integrase family K07497 - - 0.0000000000000000000002948 102.0
HFD2_k127_136102_52 exodeoxyribonuclease VII activity K03602 - 3.1.11.6 0.000000000000000000003973 95.0
HFD2_k127_136102_53 Protein of unknown function (DUF448) K07742 - - 0.000000000000007811 79.0
HFD2_k127_136102_55 Alpha/beta hydrolase family - - - 0.000000001077 60.0
HFD2_k127_136102_56 - K12512 - - 0.00000002082 66.0
HFD2_k127_136102_6 Participates in both transcription termination and antitermination K02600 - - 2.031e-305 953.0
HFD2_k127_136102_7 Belongs to the TPP enzyme family K01652 - 2.2.1.6 1.58e-299 925.0
HFD2_k127_136102_8 Amino acid permease - - - 3.312e-292 910.0
HFD2_k127_136102_9 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 2.061e-271 842.0
HFD2_k127_1392993_0 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 1.487e-223 700.0
HFD2_k127_1392993_1 Domain of unknown function (DUF1794) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002998 263.0
HFD2_k127_1392993_2 Fumarate reductase flavoprotein C-term K00239,K00244,K00278 GO:0000104,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0022900,GO:0032991,GO:0044237,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803 1.3.5.1,1.3.5.4,1.4.3.16 0.000000000000000000000000000008944 120.0
HFD2_k127_1396404_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.0 1096.0
HFD2_k127_1396404_1 Putative metal-binding motif - - - 0.0 1094.0
HFD2_k127_1396404_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000901 547.0
HFD2_k127_1396404_11 FAD linked oxidase domain protein K18930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005262 550.0
HFD2_k127_1396404_12 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007467 517.0
HFD2_k127_1396404_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 504.0
HFD2_k127_1396404_14 Acetyl-coenzyme A transporter 1 K08218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007947 443.0
HFD2_k127_1396404_15 Diadenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005933 410.0
HFD2_k127_1396404_16 Glutamine amidotransferases class-II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009584 396.0
HFD2_k127_1396404_17 Protein of unknown function (DUF2400) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 369.0
HFD2_k127_1396404_18 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 355.0
HFD2_k127_1396404_19 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 342.0
HFD2_k127_1396404_2 Heat shock 70 kDa protein K04043 - - 5.472e-293 905.0
HFD2_k127_1396404_20 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008595 357.0
HFD2_k127_1396404_21 Forkhead associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 316.0
HFD2_k127_1396404_22 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003552 301.0
HFD2_k127_1396404_23 Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 291.0
HFD2_k127_1396404_24 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K05580 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004085 314.0
HFD2_k127_1396404_25 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003301 289.0
HFD2_k127_1396404_26 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000001675 262.0
HFD2_k127_1396404_27 Abortive infection protein K07052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002924 265.0
HFD2_k127_1396404_28 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003366 247.0
HFD2_k127_1396404_29 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.000000000000000000000000000000000000000000000000000000000000000002356 256.0
HFD2_k127_1396404_3 Proton-conducting membrane transporter K00342 - 1.6.5.3 2.346e-280 869.0
HFD2_k127_1396404_30 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000001474 213.0
HFD2_k127_1396404_31 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000000000000000000000000000000000000000004382 207.0
HFD2_k127_1396404_32 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000749 220.0
HFD2_k127_1396404_33 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00330 - 1.6.5.3 0.00000000000000000000000000000000000000000000001272 175.0
HFD2_k127_1396404_34 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000000000000000001533 171.0
HFD2_k127_1396404_35 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000000000000001946 149.0
HFD2_k127_1396404_37 toxin biosynthetic process K03558 - - 0.0000004531 64.0
HFD2_k127_1396404_4 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 1.223e-241 759.0
HFD2_k127_1396404_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 3.74e-225 707.0
HFD2_k127_1396404_6 Deoxyhypusine synthase K00809 - 2.5.1.46 2.886e-207 649.0
HFD2_k127_1396404_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000486 613.0
HFD2_k127_1396404_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 633.0
HFD2_k127_1396404_9 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003133 557.0
HFD2_k127_141430_0 PFAM Integrase catalytic region - - - 0.00000000000000000000000000000000000000000000000000000000000000000103 244.0
HFD2_k127_141430_1 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.000000000000000000000000000004779 120.0
HFD2_k127_141430_2 AhpC/TSA family K03386 - 1.11.1.15 0.0000000000000004161 81.0
HFD2_k127_144783_0 Belongs to the enoyl-CoA hydratase isomerase family K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 1.764e-297 937.0
HFD2_k127_144783_1 FtsX-like permease family - - - 1.578e-272 855.0
HFD2_k127_144783_10 Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate K00598 - 2.1.1.144 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 293.0
HFD2_k127_144783_11 Smr domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006949 277.0
HFD2_k127_144783_12 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000000000000000000000000000000000000000000000000001999 240.0
HFD2_k127_144783_13 hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000000000000002661 199.0
HFD2_k127_144783_14 MarR family - - - 0.0000000000000000000000000000000004633 137.0
HFD2_k127_144783_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 9.209e-272 867.0
HFD2_k127_144783_3 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 1.783e-200 632.0
HFD2_k127_144783_4 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007145 578.0
HFD2_k127_144783_5 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 531.0
HFD2_k127_144783_6 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 361.0
HFD2_k127_144783_7 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 316.0
HFD2_k127_144783_8 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008143 334.0
HFD2_k127_144783_9 Heat shock protein DnaJ domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004861 312.0
HFD2_k127_153938_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1770.0
HFD2_k127_153938_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1458.0
HFD2_k127_153938_10 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005457 535.0
HFD2_k127_153938_11 PFAM H transporting two-sector ATPase alpha beta subunit central region K02412,K03224 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 527.0
HFD2_k127_153938_12 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000446 499.0
HFD2_k127_153938_13 nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009182 505.0
HFD2_k127_153938_14 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004221 450.0
HFD2_k127_153938_15 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 472.0
HFD2_k127_153938_16 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005905 466.0
HFD2_k127_153938_17 Cysteine-rich secretory protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 398.0
HFD2_k127_153938_18 3'-5' exonuclease K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 379.0
HFD2_k127_153938_19 Histidine kinase K15011 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003247 380.0
HFD2_k127_153938_2 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1042.0
HFD2_k127_153938_20 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003886 354.0
HFD2_k127_153938_21 soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08309 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009274,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 365.0
HFD2_k127_153938_22 polysaccharide catabolic process K03478 - 3.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002593 271.0
HFD2_k127_153938_23 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000001196 271.0
HFD2_k127_153938_24 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000001199 256.0
HFD2_k127_153938_25 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000000719 247.0
HFD2_k127_153938_27 response regulator K15012 - - 0.00000000000000000000000000000000000000000000000000000000000000000007909 254.0
HFD2_k127_153938_28 Thioredoxin K03671 - - 0.000000000000000000000000000000000000000000000000000000000006214 210.0
HFD2_k127_153938_29 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553,K14160 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000000000000000000000000000000000000007011 179.0
HFD2_k127_153938_3 Bacterial DNA polymerase III alpha subunit K14162 - 2.7.7.7 2.315e-274 885.0
HFD2_k127_153938_32 phosphorelay signal transduction system - - - 0.00000000000000000000000000000004141 129.0
HFD2_k127_153938_35 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives - - - 0.0000000000000000007532 89.0
HFD2_k127_153938_36 Flagellar assembly protein FliH K02411,K03223 - - 0.000000000000000001107 96.0
HFD2_k127_153938_37 Cupredoxin-like domain - - - 0.00000000000000278 81.0
HFD2_k127_153938_38 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.000000000000003992 76.0
HFD2_k127_153938_4 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 1.586e-258 802.0
HFD2_k127_153938_5 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 3.259e-215 674.0
HFD2_k127_153938_6 Transporter associated domain K03699 - - 2.162e-199 630.0
HFD2_k127_153938_7 Belongs to the CarA family K01956 - 6.3.5.5 6.466e-195 639.0
HFD2_k127_153938_8 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 604.0
HFD2_k127_153938_9 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 524.0
HFD2_k127_1594497_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 8.56e-275 854.0
HFD2_k127_1594497_1 two component, sigma54 specific, transcriptional regulator, Fis family - - - 8.829e-214 699.0
HFD2_k127_1594497_10 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000003829 192.0
HFD2_k127_1594497_2 Rod shape-determining protein K03569 - - 2.726e-199 623.0
HFD2_k127_1594497_3 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 594.0
HFD2_k127_1594497_4 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 578.0
HFD2_k127_1594497_5 Histidine kinase K07710,K10125 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 576.0
HFD2_k127_1594497_6 heat shock protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006466 354.0
HFD2_k127_1594497_7 glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 289.0
HFD2_k127_1594497_8 Belongs to the ompA family K03286 - - 0.00000000000000000000000000000000000000000000000000000000000001503 234.0
HFD2_k127_1594497_9 Pfam:DUF2029 - - - 0.0000000000000000000000000000000000000000000000000000000000008934 227.0
HFD2_k127_1635255_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 4.35e-294 933.0
HFD2_k127_1635255_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 6.001e-222 698.0
HFD2_k127_1635255_10 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001767 285.0
HFD2_k127_1635255_12 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000006168 262.0
HFD2_k127_1635255_13 Acid phosphatase homologues - - - 0.0000000000000000000000000000000000000000000001475 182.0
HFD2_k127_1635255_14 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000003734 173.0
HFD2_k127_1635255_15 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000007188 173.0
HFD2_k127_1635255_17 PFAM Smr protein MutS2 - - - 0.00000000000000000000000003599 119.0
HFD2_k127_1635255_2 Belongs to the radical SAM superfamily. RlmN family K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 520.0
HFD2_k127_1635255_20 Protein of unknown function (DUF3106) - - - 0.000000000000000009644 94.0
HFD2_k127_1635255_21 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000005312 85.0
HFD2_k127_1635255_22 AntiSigma factor - - - 0.00000009118 64.0
HFD2_k127_1635255_3 Phosphate transporter family K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 534.0
HFD2_k127_1635255_4 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005949 518.0
HFD2_k127_1635255_5 Metallopeptidase family M24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 443.0
HFD2_k127_1635255_6 Related to alanyl-tRNA synthetase HxxxH domain K01872,K07050 - 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 435.0
HFD2_k127_1635255_7 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 392.0
HFD2_k127_1635255_8 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 312.0
HFD2_k127_1635255_9 PFAM Amidohydrolase 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004726 334.0
HFD2_k127_1641132_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 9.748e-272 846.0
HFD2_k127_1641132_1 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840,K15778 - 5.4.2.2,5.4.2.8 9.344e-232 724.0
HFD2_k127_1641132_10 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 368.0
HFD2_k127_1641132_11 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 366.0
HFD2_k127_1641132_12 PFAM ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 342.0
HFD2_k127_1641132_13 PFAM PTS system mannose fructose sorbose family IID component K02796 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006352 309.0
HFD2_k127_1641132_14 transcriptional regulator K09017,K18301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000143 239.0
HFD2_k127_1641132_15 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000004454 215.0
HFD2_k127_1641132_16 PTS system K02795 - - 0.0000000000000000000000000000000000000000000000000000000004677 209.0
HFD2_k127_1641132_17 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000000002163 211.0
HFD2_k127_1641132_18 PFAM PTS system sorbose subfamily IIB component K02794 - 2.7.1.191 0.00000000000000000000000000000000000000000000000001439 191.0
HFD2_k127_1641132_19 PFAM PTS system fructose subfamily IIA component K02793 - 2.7.1.191 0.0000000000000000000000000000000000000000000004321 170.0
HFD2_k127_1641132_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 5.522e-208 664.0
HFD2_k127_1641132_20 PTS HPr component phosphorylation site K11189 - - 0.000000000000000000000000000002678 122.0
HFD2_k127_1641132_21 PFAM Lytic transglycosylase-like, catalytic - - - 0.000000000000000000000000001156 132.0
HFD2_k127_1641132_22 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000000000000000000825 101.0
HFD2_k127_1641132_23 - K20150 - 1.16.9.1 0.0000002739 63.0
HFD2_k127_1641132_3 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 554.0
HFD2_k127_1641132_4 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003719 541.0
HFD2_k127_1641132_5 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003892 544.0
HFD2_k127_1641132_6 Mannose-6-phosphate isomerase K00971 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 550.0
HFD2_k127_1641132_7 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006066 517.0
HFD2_k127_1641132_8 COG0618 Exopolyphosphatase-related proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007512 485.0
HFD2_k127_1641132_9 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006431 415.0
HFD2_k127_1726116_0 Pyruvate ferredoxin/flavodoxin oxidoreductase K00179 - 1.2.7.8 0.0 1365.0
HFD2_k127_1726116_1 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit K01844 - 5.4.3.3 6.963e-276 855.0
HFD2_k127_1726116_10 Enoyl-CoA hydratase/isomerase K16427 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016701,GO:0016702,GO:0042802,GO:0051213,GO:0055114 1.13.11.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 423.0
HFD2_k127_1726116_11 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 399.0
HFD2_k127_1726116_12 Dimerisation domain of d-ornithine 4,5-aminomutase K18011 - 5.4.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 377.0
HFD2_k127_1726116_13 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007641 346.0
HFD2_k127_1726116_14 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 320.0
HFD2_k127_1726116_15 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004779 303.0
HFD2_k127_1726116_16 PFAM Patatin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001264 274.0
HFD2_k127_1726116_17 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003705 282.0
HFD2_k127_1726116_18 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001436 268.0
HFD2_k127_1726116_2 Indolepyruvate ferredoxin oxidoreductase K00179,K04090 - 1.2.7.8 3.64e-258 823.0
HFD2_k127_1726116_20 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007092 258.0
HFD2_k127_1726116_21 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000001362 220.0
HFD2_k127_1726116_22 Thioesterase superfamily K18014 - 4.3.1.14 0.000000000000000000000000000000000000000000000000000000000005219 220.0
HFD2_k127_1726116_23 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00180 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000001808 227.0
HFD2_k127_1726116_24 Domain of unknown function (DUF4863) - - - 0.00000000000000000000000000000000000000000000000000000003189 203.0
HFD2_k127_1726116_26 Protein of unknown function (DUF429) - - - 0.000000000000000000000000000000000000000001786 179.0
HFD2_k127_1726116_27 guanyl-nucleotide exchange factor activity K14475,K20276 - - 0.0000000000000000000000000000000001076 156.0
HFD2_k127_1726116_29 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000004695 117.0
HFD2_k127_1726116_3 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 4.057e-229 715.0
HFD2_k127_1726116_30 SEC-C Motif Domain Protein - - - 0.0000000000000000000000001061 121.0
HFD2_k127_1726116_31 Putative zinc-finger - - - 0.0000000000000000000000001677 123.0
HFD2_k127_1726116_32 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000176 124.0
HFD2_k127_1726116_33 Cytochrome C' - - - 0.0000000000000000002211 94.0
HFD2_k127_1726116_34 PFAM cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.00000000000005657 85.0
HFD2_k127_1726116_35 - - - - 0.0000000008575 71.0
HFD2_k127_1726116_36 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000006916 54.0
HFD2_k127_1726116_4 Ammonium Transporter Family K03320 - - 1.169e-195 619.0
HFD2_k127_1726116_5 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007513 618.0
HFD2_k127_1726116_6 endonuclease activity K07451 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 580.0
HFD2_k127_1726116_7 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 499.0
HFD2_k127_1726116_8 Pfam:Kce K18013 - 2.3.1.247 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008897 450.0
HFD2_k127_1726116_9 tRNA nucleotidyltransferase domain 2 putative K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 446.0
HFD2_k127_1754744_0 PFAM ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006648 372.0
HFD2_k127_1754744_1 Periplasmic binding protein K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008101 383.0
HFD2_k127_1754744_2 PFAM AMP-dependent synthetase and ligase K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004009 358.0
HFD2_k127_1754744_3 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 325.0
HFD2_k127_1754744_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000366 311.0
HFD2_k127_1754744_5 AAA domain, putative AbiEii toxin, Type IV TA system K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003896 261.0
HFD2_k127_1754744_6 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000002721 252.0
HFD2_k127_1754744_7 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000009056 229.0
HFD2_k127_1754744_8 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000001688 251.0
HFD2_k127_1754744_9 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000142 227.0
HFD2_k127_1757355_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 608.0
HFD2_k127_1757355_1 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004219 245.0
HFD2_k127_1757355_2 Protein of unknown function (DUF2721) - - - 0.00000000000000000000000000000008961 130.0
HFD2_k127_1770408_0 - - - - 3.012e-314 974.0
HFD2_k127_1770408_1 - - - - 1.452e-283 917.0
HFD2_k127_1770408_10 Sensor protein, DUF3365, HAMP and PAS domain-containing, heme-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003845 428.0
HFD2_k127_1770408_11 carbon starvation protein CstA K06200 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 414.0
HFD2_k127_1770408_12 C-terminal binding-module, SLH-like, of glucodextranase K01178 - 3.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 374.0
HFD2_k127_1770408_13 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 355.0
HFD2_k127_1770408_14 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007446 334.0
HFD2_k127_1770408_15 PFAM ABC transporter K05847 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006752 334.0
HFD2_k127_1770408_16 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 323.0
HFD2_k127_1770408_17 Protein involved in meta-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002801 255.0
HFD2_k127_1770408_18 C-terminal binding-module, SLH-like, of glucodextranase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002633 241.0
HFD2_k127_1770408_19 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000000001461 199.0
HFD2_k127_1770408_2 Alpha-amylase domain K01176 - 3.2.1.1 1.245e-216 683.0
HFD2_k127_1770408_20 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000001044 197.0
HFD2_k127_1770408_21 Universal stress protein - - - 0.00000000000000000000000000000000000000003944 156.0
HFD2_k127_1770408_22 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.000000000000000000000000000000000001249 151.0
HFD2_k127_1770408_23 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000004114 115.0
HFD2_k127_1770408_24 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000004945 106.0
HFD2_k127_1770408_25 Phosphopantetheine attachment site - - - 0.00000000000000002524 94.0
HFD2_k127_1770408_26 Protein of unknown function (DUF2905) - - - 0.0000000000000004393 90.0
HFD2_k127_1770408_27 2Fe-2S -binding domain K02192 - - 0.00000302 52.0
HFD2_k127_1770408_3 Sugar ABC transporter permease K10109,K15770,K15771 - - 1.806e-213 705.0
HFD2_k127_1770408_4 Alpha-amylase domain K01176 - 3.2.1.1 1.609e-195 623.0
HFD2_k127_1770408_5 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 6.599e-195 632.0
HFD2_k127_1770408_6 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 593.0
HFD2_k127_1770408_7 Bacterial extracellular solute-binding protein K15770 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 582.0
HFD2_k127_1770408_8 Belongs to the ABC transporter superfamily K05816,K10112 - 3.6.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005023 513.0
HFD2_k127_1770408_9 Binding-protein-dependent transport system inner membrane component K10110,K15772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007511 463.0
HFD2_k127_1787394_0 Molybdopterin oxidoreductase K00370,K17050 - 1.7.5.1 0.0 1016.0
HFD2_k127_1787394_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 6.331e-317 979.0
HFD2_k127_1787394_10 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.0000000000000000001063 105.0
HFD2_k127_1787394_12 Cytochrome c - - - 0.0000007294 62.0
HFD2_k127_1787394_2 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298 - 1.10.3.10,1.9.3.1 3.768e-294 926.0
HFD2_k127_1787394_3 4Fe-4S dicluster domain K17051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008862 512.0
HFD2_k127_1787394_4 Cytochrome C oxidase subunit II, transmembrane domain K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009293 457.0
HFD2_k127_1787394_5 Pectinacetylesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008957 363.0
HFD2_k127_1787394_6 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 343.0
HFD2_k127_1787394_7 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004951 325.0
HFD2_k127_1787394_8 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 334.0
HFD2_k127_1787394_9 Cytochrome c K17052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000287 290.0
HFD2_k127_1806446_0 Malate synthase K01638 - 2.3.3.9 0.0 1240.0
HFD2_k127_1806446_1 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582 - 3.1.11.5 0.0 1237.0
HFD2_k127_1806446_10 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006504 472.0
HFD2_k127_1806446_11 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007433 467.0
HFD2_k127_1806446_12 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009103 466.0
HFD2_k127_1806446_13 COG2755 Lysophospholipase L1 and related esterases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 454.0
HFD2_k127_1806446_14 PFAM Alcohol dehydrogenase zinc-binding domain protein K07119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 435.0
HFD2_k127_1806446_15 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009106 402.0
HFD2_k127_1806446_16 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004425 393.0
HFD2_k127_1806446_17 TRAP transporter solute receptor TAXI family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 371.0
HFD2_k127_1806446_18 regulation of single-species biofilm formation K13572,K13573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003304 353.0
HFD2_k127_1806446_19 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 364.0
HFD2_k127_1806446_2 PD-(D/E)XK nuclease superfamily - - - 1.209e-298 944.0
HFD2_k127_1806446_20 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003611 341.0
HFD2_k127_1806446_21 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006224 325.0
HFD2_k127_1806446_22 hydrolase, CocE NonD family K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006338 304.0
HFD2_k127_1806446_23 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004886 297.0
HFD2_k127_1806446_24 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 295.0
HFD2_k127_1806446_25 Integral membrane protein (intg_mem_TP0381) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002342 280.0
HFD2_k127_1806446_26 regulation of single-species biofilm formation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001956 293.0
HFD2_k127_1806446_27 EcsC protein family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006817 260.0
HFD2_k127_1806446_28 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000005787 247.0
HFD2_k127_1806446_29 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000429 232.0
HFD2_k127_1806446_3 Tripartite ATP-independent periplasmic transporter, DctM component - - - 7.281e-260 827.0
HFD2_k127_1806446_30 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001303 227.0
HFD2_k127_1806446_31 shikimate kinase activity K00891,K13829,K15546 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000001584 211.0
HFD2_k127_1806446_32 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.0000000000000000000000000000000000000000000000000000006347 203.0
HFD2_k127_1806446_33 - - - - 0.00000000000000000000000000000000000000000001607 177.0
HFD2_k127_1806446_34 PFAM Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000007026 171.0
HFD2_k127_1806446_35 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000001489 172.0
HFD2_k127_1806446_36 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000003671 165.0
HFD2_k127_1806446_37 - - - - 0.0000000000000000000000000000000000001914 142.0
HFD2_k127_1806446_38 PFAM Thiolase K00626 - 2.3.1.9 0.0000000000000000000000000000001201 139.0
HFD2_k127_1806446_39 - - - - 0.000000000000000000000000000000588 138.0
HFD2_k127_1806446_4 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 4.723e-245 763.0
HFD2_k127_1806446_40 Nudix hydrolase K03574 - 3.6.1.55 0.0000000000000000000000000001509 119.0
HFD2_k127_1806446_41 Domain of unknown function (DUF309) K09763 - - 0.00000000000000000001287 98.0
HFD2_k127_1806446_42 - - - - 0.00000000000001411 87.0
HFD2_k127_1806446_44 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.00001222 59.0
HFD2_k127_1806446_45 WYL domain K13573 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0001045 54.0
HFD2_k127_1806446_5 CoA binding domain K01905,K22224 - 6.2.1.13 3.138e-202 655.0
HFD2_k127_1806446_6 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 1.506e-194 619.0
HFD2_k127_1806446_7 CoA-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007267 562.0
HFD2_k127_1806446_8 Biotin-lipoyl like K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 513.0
HFD2_k127_1806446_9 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 497.0
HFD2_k127_1816342_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 0.0 1137.0
HFD2_k127_1816342_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 9.928e-313 1000.0
HFD2_k127_1816342_10 Insulinase (Peptidase family M16) - - - 1.981e-194 627.0
HFD2_k127_1816342_11 Bacterial regulatory protein, Fis family K11384 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003471 612.0
HFD2_k127_1816342_12 HAMP domain K11383 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 585.0
HFD2_k127_1816342_13 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 570.0
HFD2_k127_1816342_14 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 565.0
HFD2_k127_1816342_15 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 550.0
HFD2_k127_1816342_16 ATPase involved in DNA repair K03546 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005713 527.0
HFD2_k127_1816342_17 Two component, sigma54 specific, transcriptional regulator, Fis family K07712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 516.0
HFD2_k127_1816342_18 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004288 498.0
HFD2_k127_1816342_19 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006819 489.0
HFD2_k127_1816342_2 Signal transduction histidine kinase - - - 2.112e-306 993.0
HFD2_k127_1816342_20 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 488.0
HFD2_k127_1816342_21 NUBPL iron-transfer P-loop NTPase K04562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008564 456.0
HFD2_k127_1816342_22 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 452.0
HFD2_k127_1816342_23 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015,K15893 - 1.1.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004573 434.0
HFD2_k127_1816342_24 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 396.0
HFD2_k127_1816342_25 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006077 392.0
HFD2_k127_1816342_26 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009052 372.0
HFD2_k127_1816342_27 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 364.0
HFD2_k127_1816342_29 HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 364.0
HFD2_k127_1816342_3 Amino acid permease - - - 2.119e-290 910.0
HFD2_k127_1816342_31 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008791 369.0
HFD2_k127_1816342_32 COG0767 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006365 328.0
HFD2_k127_1816342_33 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005399 324.0
HFD2_k127_1816342_34 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 319.0
HFD2_k127_1816342_35 Sterol desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 306.0
HFD2_k127_1816342_36 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001288 258.0
HFD2_k127_1816342_37 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001766 244.0
HFD2_k127_1816342_38 pseudouridine synthase activity K06177,K06179,K06180 - 5.4.99.23,5.4.99.24,5.4.99.28,5.4.99.29 0.00000000000000000000000000000000000000000000000000000000000000000002789 259.0
HFD2_k127_1816342_39 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000000000000009597 256.0
HFD2_k127_1816342_4 Belongs to the IlvD Edd family K01687 - 4.2.1.9 9.755e-289 896.0
HFD2_k127_1816342_40 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity K01118 - - 0.000000000000000000000000000000000000000000000000000000000000000009965 229.0
HFD2_k127_1816342_41 domain, Protein K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000002402 236.0
HFD2_k127_1816342_42 PFAM PHP domain protein K01104 - 3.1.3.48 0.000000000000000000000000000000000000000000000000000000000000002658 225.0
HFD2_k127_1816342_43 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000006514 214.0
HFD2_k127_1816342_44 sequence-specific DNA binding - - - 0.000000000000000000000000000000000000000000000000000000000001757 218.0
HFD2_k127_1816342_45 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000000000000000000000000005264 205.0
HFD2_k127_1816342_46 RNA polymerase K03088 - - 0.000000000000000000000000000000000000000000000000000001022 204.0
HFD2_k127_1816342_47 LysM domain - - - 0.00000000000000000000000000000000000000000000000001269 188.0
HFD2_k127_1816342_48 - - - - 0.0000000000000000000000000000000000000000004051 158.0
HFD2_k127_1816342_49 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.0000000000000000000000000000000000000000008216 178.0
HFD2_k127_1816342_5 ABC transporter K06147,K06148 - - 9.329e-269 840.0
HFD2_k127_1816342_50 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000884 160.0
HFD2_k127_1816342_51 Evidence 4 Homologs of previously reported genes of K15977 - - 0.000000000000000000000000000000000000000001496 161.0
HFD2_k127_1816342_52 - - - - 0.0000000000000000000000000000000000000001705 159.0
HFD2_k127_1816342_54 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000000000000000001827 146.0
HFD2_k127_1816342_55 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000002315 137.0
HFD2_k127_1816342_56 - - - - 0.000000000000000000000000000000001311 139.0
HFD2_k127_1816342_57 Small Multidrug Resistance protein K11741 - - 0.00000000000000000000000000007657 118.0
HFD2_k127_1816342_58 Belongs to the UPF0109 family K06960 - - 0.0000000000000000000000000001687 121.0
HFD2_k127_1816342_59 Thioesterase superfamily - - - 0.0000000000000000000000001232 113.0
HFD2_k127_1816342_6 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 1.447e-258 809.0
HFD2_k127_1816342_60 Nucleic acid binding OB-fold tRNA helicase-type - - - 0.0000000000000000000000001391 120.0
HFD2_k127_1816342_61 Dodecin K09165 - - 0.00000000000000000000001827 104.0
HFD2_k127_1816342_62 - - - - 0.000000000000000000165 95.0
HFD2_k127_1816342_63 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.0000000000000000008478 87.0
HFD2_k127_1816342_65 Histidine kinase - - - 0.0000000000000005244 81.0
HFD2_k127_1816342_66 PFAM Iron sulphur-containing domain, CDGSH-type - - - 0.000000000000005789 82.0
HFD2_k127_1816342_68 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity K01118 - - 0.0000001347 57.0
HFD2_k127_1816342_69 - - - - 0.00002409 48.0
HFD2_k127_1816342_7 HAD superfamily (subfamily IG) hydrolase 5'-Nucleotidase - - - 1.446e-217 692.0
HFD2_k127_1816342_70 Cupin 2, conserved barrel domain protein - - - 0.0003989 50.0
HFD2_k127_1816342_8 Transglycosylase SLT domain K08309 - - 1.083e-204 693.0
HFD2_k127_1816342_9 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 2.974e-201 631.0
HFD2_k127_1816622_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1325.0
HFD2_k127_1816622_1 ATP dependent DNA ligase domain protein K01971 - 6.5.1.1 2.205e-314 1019.0
HFD2_k127_1816622_10 PFAM Band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003486 476.0
HFD2_k127_1816622_11 NAD dependent epimerase/dehydratase family K05281 - 1.3.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 446.0
HFD2_k127_1816622_12 Aldo keto reductase K19265 GO:0003674,GO:0003824,GO:0006081,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0033554,GO:0042180,GO:0042182,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0050896,GO:0051596,GO:0051716,GO:0055114,GO:0071704,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008874 431.0
HFD2_k127_1816622_13 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007339 407.0
HFD2_k127_1816622_14 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005403 397.0
HFD2_k127_1816622_15 FeS assembly protein SufD K09015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 394.0
HFD2_k127_1816622_16 ATP ADP translocase K03301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004686 406.0
HFD2_k127_1816622_17 FeS assembly ATPase SufC K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006112 383.0
HFD2_k127_1816622_18 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 364.0
HFD2_k127_1816622_19 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007079 353.0
HFD2_k127_1816622_2 FeS assembly protein SufB K09014 - - 1.664e-269 850.0
HFD2_k127_1816622_20 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 369.0
HFD2_k127_1816622_21 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 355.0
HFD2_k127_1816622_22 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 340.0
HFD2_k127_1816622_23 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 326.0
HFD2_k127_1816622_24 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009285 315.0
HFD2_k127_1816622_25 uridine phosphorylase activity K00757 - 2.4.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006993 313.0
HFD2_k127_1816622_26 alpha/beta hydrolase fold K01563,K22318 - 3.8.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 310.0
HFD2_k127_1816622_27 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003166 287.0
HFD2_k127_1816622_28 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004113 282.0
HFD2_k127_1816622_29 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001609 293.0
HFD2_k127_1816622_3 Peptidase dimerisation domain - - - 3.981e-207 655.0
HFD2_k127_1816622_30 dimethylhistidine N-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006046 271.0
HFD2_k127_1816622_31 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008457 261.0
HFD2_k127_1816622_32 RNA polymerase K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001143 257.0
HFD2_k127_1816622_33 SUF system FeS assembly protein K04488 - - 0.0000000000000000000000000000000000000000000000000000000000004764 218.0
HFD2_k127_1816622_34 Iron-sulfur cluster assembly protein - - - 0.000000000000000000000000000000000000000000000000000000002582 213.0
HFD2_k127_1816622_35 TPM domain K06872 - - 0.0000000000000000000000000000000000000000000000000000001125 211.0
HFD2_k127_1816622_36 Membrane K08988 - - 0.0000000000000000000000000000000000000000000000000000005774 199.0
HFD2_k127_1816622_37 - - - - 0.00000000000000000000000000000000000000000000000000286 190.0
HFD2_k127_1816622_38 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000001352 175.0
HFD2_k127_1816622_39 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000001191 177.0
HFD2_k127_1816622_4 PFAM Rh family protein ammonium transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000783 567.0
HFD2_k127_1816622_40 NfeD-like C-terminal, partner-binding - - - 0.0000000000000000000000000000000000000000004439 162.0
HFD2_k127_1816622_41 transcriptional regulator, Rrf2 family - - - 0.00000000000000000000000000000000000000008668 155.0
HFD2_k127_1816622_42 Glyoxalase bleomycin resistance - - - 0.000000000000000000000000000000000000001557 168.0
HFD2_k127_1816622_43 Winged helix-turn helix - - - 0.00000000000000000000000000000000000004577 149.0
HFD2_k127_1816622_44 6-O-methylguanine DNA methyltransferase, DNA binding domain K07443 - - 0.000000000000000000000000000000000005383 141.0
HFD2_k127_1816622_45 PEGA domain - - - 0.000000000000000000000000000003483 123.0
HFD2_k127_1816622_46 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000001824 116.0
HFD2_k127_1816622_48 ThiS family K03636 - - 0.000000000000004779 89.0
HFD2_k127_1816622_49 fumarate hydratase activity - - - 0.0000000000009634 76.0
HFD2_k127_1816622_5 Beta-eliminating lyase K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005513 543.0
HFD2_k127_1816622_6 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 560.0
HFD2_k127_1816622_7 protein related to plant photosystem II stability assembly factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008816 515.0
HFD2_k127_1816622_8 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005539 488.0
HFD2_k127_1816622_9 DinB superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 488.0
HFD2_k127_182722_0 Male sterility protein K01897 - 6.2.1.3 0.0 1872.0
HFD2_k127_182722_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1615.0
HFD2_k127_182722_10 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679,K01744 - 4.2.1.2,4.3.1.1 6.968e-198 630.0
HFD2_k127_182722_11 N-terminal domain of unknown function (DUF4140) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 603.0
HFD2_k127_182722_12 Belongs to the glycosyl hydrolase 13 family K01187 - 3.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006444 623.0
HFD2_k127_182722_13 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005739 559.0
HFD2_k127_182722_14 Belongs to the SAICAR synthetase family K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004822 550.0
HFD2_k127_182722_15 epimerase dehydratase K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006496 482.0
HFD2_k127_182722_16 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 466.0
HFD2_k127_182722_17 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005577 450.0
HFD2_k127_182722_18 fatty acid beta-oxidation using acyl-CoA dehydrogenase K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005302 442.0
HFD2_k127_182722_19 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008697 439.0
HFD2_k127_182722_2 Belongs to the aconitase IPM isomerase family K01682 - 4.2.1.3,4.2.1.99 0.0 1384.0
HFD2_k127_182722_20 electron transfer activity K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 404.0
HFD2_k127_182722_21 major pilin protein fima - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 402.0
HFD2_k127_182722_22 Tannase and feruloyl esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005065 406.0
HFD2_k127_182722_23 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 375.0
HFD2_k127_182722_24 Peptidase family M50 K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 379.0
HFD2_k127_182722_26 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003665 360.0
HFD2_k127_182722_27 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000727 354.0
HFD2_k127_182722_28 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 350.0
HFD2_k127_182722_29 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008616 343.0
HFD2_k127_182722_3 acyl-CoA dehydrogenase activity K00249 - 1.3.8.7 0.0 1108.0
HFD2_k127_182722_30 spore germination K15270 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003297 349.0
HFD2_k127_182722_31 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004912 308.0
HFD2_k127_182722_32 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002308 312.0
HFD2_k127_182722_33 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 303.0
HFD2_k127_182722_34 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 305.0
HFD2_k127_182722_36 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 - 2.1.1.200 0.0000000000000000000000000000000000000000000000000000000000000000000000000001277 266.0
HFD2_k127_182722_37 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005114 262.0
HFD2_k127_182722_39 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001357 253.0
HFD2_k127_182722_4 Domain of unknown function (DUF2088) - - - 1.696e-298 936.0
HFD2_k127_182722_40 HAD-hyrolase-like K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000001142 241.0
HFD2_k127_182722_41 AMMECR1 K09141 - - 0.00000000000000000000000000000000000000000000000000000000004207 227.0
HFD2_k127_182722_42 DNA-templated transcription, initiation K03088,K11333 - 1.3.7.14,1.3.7.15 0.0000000000000000000000000000000000000000000000000000000003198 207.0
HFD2_k127_182722_43 hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000000000000000003259 208.0
HFD2_k127_182722_44 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000008323 215.0
HFD2_k127_182722_45 helix_turn_helix, arabinose operon control protein K07506 - - 0.0000000000000000000000000000000000000000000000006005 188.0
HFD2_k127_182722_46 - - - - 0.0000000000000000000000000000000000000000000003383 177.0
HFD2_k127_182722_47 CutA1 divalent ion tolerance protein K03926 - - 0.0000000000000000000000000000000000000000000008542 167.0
HFD2_k127_182722_48 Protein of unknown function (DUF3015) - - - 0.000000000000000000000000000000000000000000001102 179.0
HFD2_k127_182722_5 Electron transfer flavoprotein-ubiquinone K00311 - 1.5.5.1 3.537e-292 907.0
HFD2_k127_182722_50 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000001652 174.0
HFD2_k127_182722_51 DNA-templated transcription, initiation K03088,K11333 - 1.3.7.14,1.3.7.15 0.000000000000000000000000000000000000000384 169.0
HFD2_k127_182722_52 Response regulator, receiver - - - 0.00000000000000000000000000000000000003413 148.0
HFD2_k127_182722_53 Protein of unknown function (DUF3015) - - - 0.000000000000000000000000000000000003766 142.0
HFD2_k127_182722_55 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000002993 140.0
HFD2_k127_182722_56 sequence-specific DNA binding - - - 0.0000000000000000000000000000001652 124.0
HFD2_k127_182722_57 Putative peptidoglycan binding domain - - - 0.0000000000000000000000000000002497 131.0
HFD2_k127_182722_59 PFAM EamA-like transporter family - - - 0.000000000000000000000000000009293 134.0
HFD2_k127_182722_6 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.247e-229 719.0
HFD2_k127_182722_60 Cupin 2, conserved barrel domain protein K18991 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009438,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019172,GO:0019243,GO:0019249,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046185,GO:0046394,GO:0051596,GO:0061727,GO:0071704,GO:0072330,GO:1901575,GO:1901576,GO:1901615,GO:1901617 - 0.000000000000000000000000000248 119.0
HFD2_k127_182722_62 - - - - 0.0000001334 61.0
HFD2_k127_182722_63 Insulinase (Peptidase family M16) - - - 0.000001923 54.0
HFD2_k127_182722_64 PAS sensor protein - - - 0.000051 49.0
HFD2_k127_182722_65 Dienelactone hydrolase - - - 0.0004224 52.0
HFD2_k127_182722_66 - - - - 0.0005136 48.0
HFD2_k127_182722_67 amine dehydrogenase activity - - - 0.0006426 53.0
HFD2_k127_182722_7 signal peptide peptidase SppA, 36K type K04773 - - 8.294e-207 676.0
HFD2_k127_182722_8 Domain of unknown function (DUF4105) - - - 9.889e-207 661.0
HFD2_k127_182722_9 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 9.092e-202 641.0
HFD2_k127_1836465_0 Trypsin - - - 0.00000000000000000000000000000000000000000000000000000000005813 209.0
HFD2_k127_1836465_1 NAD(P)H-binding K01784 - 5.1.3.2 0.000000000000000633 81.0
HFD2_k127_1846093_0 Beta-eliminating lyase K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008185 493.0
HFD2_k127_1846093_1 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008398 392.0
HFD2_k127_1846093_2 PAP2 superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006131 249.0
HFD2_k127_1846093_3 secondary active sulfate transmembrane transporter activity K06901 - - 0.0000000004652 61.0
HFD2_k127_1852454_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.0 1094.0
HFD2_k127_1852454_1 Heat shock 70 kDa protein K04043 - - 7.719e-273 847.0
HFD2_k127_1852454_10 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 488.0
HFD2_k127_1852454_11 HD domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 486.0
HFD2_k127_1852454_12 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 448.0
HFD2_k127_1852454_13 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005628 389.0
HFD2_k127_1852454_14 acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 394.0
HFD2_k127_1852454_15 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 308.0
HFD2_k127_1852454_16 Sterol carrier protein - - - 0.00000000000000000000000000000000000000000003931 164.0
HFD2_k127_1852454_17 cysteine-type peptidase activity K13695 - - 0.00000000000000000000000000000000000001984 151.0
HFD2_k127_1852454_18 photosystem II stabilization K02237,K02238,K02719 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0009521,GO:0009523,GO:0009579,GO:0016020,GO:0030075,GO:0030096,GO:0032991,GO:0034357,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044425,GO:0044436,GO:0044444,GO:0044459,GO:0044464,GO:0071944,GO:0098796,GO:0098797 - 0.00000000000000000000000000000000000409 142.0
HFD2_k127_1852454_19 COG1484 DNA replication protein - - - 0.000000000000000000000000001809 120.0
HFD2_k127_1852454_2 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 4.478e-254 788.0
HFD2_k127_1852454_21 COG1484 DNA replication protein - - - 0.00000000000000001334 91.0
HFD2_k127_1852454_3 Histidine ammonia-lyase K01745 - 4.3.1.3 1.844e-237 742.0
HFD2_k127_1852454_4 aspartate glutamate uridylate kinase K00928 - 2.7.2.4 1.104e-231 729.0
HFD2_k127_1852454_5 Amidohydrolase family - - - 1.355e-210 667.0
HFD2_k127_1852454_6 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 2.138e-207 654.0
HFD2_k127_1852454_7 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006221 583.0
HFD2_k127_1852454_8 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 573.0
HFD2_k127_1852454_9 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 509.0
HFD2_k127_1861986_0 Peptidase family M3 K01392 - 3.4.24.15 2.512e-292 909.0
HFD2_k127_1861986_1 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 489.0
HFD2_k127_1861986_2 AMP-binding enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 456.0
HFD2_k127_1861986_3 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 337.0
HFD2_k127_1861986_4 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000002983 209.0
HFD2_k127_1894689_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000002882 214.0
HFD2_k127_1894689_1 Late embryogenesis abundant protein - - - 0.0000000000000000000000000000000000000000000000000000002418 209.0
HFD2_k127_1894689_2 Methionine synthase K00548 - 2.1.1.13 0.000000005119 57.0
HFD2_k127_1896217_0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 463.0
HFD2_k127_1896217_1 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 444.0
HFD2_k127_1896217_11 regulation of DNA repair K03565 - - 0.00000000000000000000000000000000000000000000003727 175.0
HFD2_k127_1896217_12 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000000687 140.0
HFD2_k127_1896217_2 DNA methylase K00590 - 2.1.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 426.0
HFD2_k127_1896217_3 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 364.0
HFD2_k127_1896217_4 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 361.0
HFD2_k127_1896217_5 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007994 361.0
HFD2_k127_1896217_6 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 295.0
HFD2_k127_1896217_7 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001598 275.0
HFD2_k127_1896217_8 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000001655 243.0
HFD2_k127_1896217_9 FHA domain - - - 0.00000000000000000000000000000000000000000000000000000000004961 227.0
HFD2_k127_1926135_0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) K01214,K02438 - 3.2.1.196,3.2.1.68 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009637 598.0
HFD2_k127_1926135_1 Biotin-lipoyl like K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004839 425.0
HFD2_k127_1939317_0 Methionine synthase K00548 - 2.1.1.13 0.0 1719.0
HFD2_k127_1939317_1 PFAM glycosyl transferase family 51 K05366 - 2.4.1.129,3.4.16.4 0.0 1122.0
HFD2_k127_1939317_10 Exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 464.0
HFD2_k127_1939317_11 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 451.0
HFD2_k127_1939317_12 Electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 430.0
HFD2_k127_1939317_13 Electron transfer flavoprotein K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006541 431.0
HFD2_k127_1939317_14 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 401.0
HFD2_k127_1939317_15 PFAM Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004613 346.0
HFD2_k127_1939317_16 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008017 347.0
HFD2_k127_1939317_17 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 363.0
HFD2_k127_1939317_18 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006511 363.0
HFD2_k127_1939317_19 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 331.0
HFD2_k127_1939317_2 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1074.0
HFD2_k127_1939317_20 Sodium/calcium exchanger protein K07300 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003332 337.0
HFD2_k127_1939317_21 Domain of unknown function (DUF4382) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 340.0
HFD2_k127_1939317_22 Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 321.0
HFD2_k127_1939317_23 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 305.0
HFD2_k127_1939317_24 PFAM Phosphomethylpyrimidine kinase K00941,K14153,K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002575 290.0
HFD2_k127_1939317_25 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000001835 247.0
HFD2_k127_1939317_26 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000002292 237.0
HFD2_k127_1939317_27 thiolester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000004322 219.0
HFD2_k127_1939317_28 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000000000000000000001539 190.0
HFD2_k127_1939317_29 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000002465 178.0
HFD2_k127_1939317_3 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 2.793e-271 843.0
HFD2_k127_1939317_30 MOSC domain - - - 0.0000000000000000000000000000000000000000000000412 181.0
HFD2_k127_1939317_31 - - - - 0.0000000000000000000000000000000000000000000008372 173.0
HFD2_k127_1939317_32 Ubiquinol-cytochrome C reductase - - - 0.00000000000000000000000000000000000000000001444 166.0
HFD2_k127_1939317_33 domain, Protein - - - 0.0000000000000000000000000000000000000001117 172.0
HFD2_k127_1939317_34 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0000000000000000000000000000000000000002985 170.0
HFD2_k127_1939317_35 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000002484 165.0
HFD2_k127_1939317_36 Eukaryotic integral membrane protein (DUF1751) - - - 0.0000000000000000000000000000000005408 139.0
HFD2_k127_1939317_37 PFAM amino acid-binding ACT domain protein - - - 0.000000000000000000000000000000007362 141.0
HFD2_k127_1939317_38 NTPase - - - 0.0000000000000000000000000001951 123.0
HFD2_k127_1939317_39 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03117 - - 0.00000000000000000000000001539 113.0
HFD2_k127_1939317_4 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 624.0
HFD2_k127_1939317_40 PFAM MaoC domain protein dehydratase - - - 0.00000000000000000000000003541 119.0
HFD2_k127_1939317_41 Domain of unknown function (DUF1844) - - - 0.000000000000000000000001404 121.0
HFD2_k127_1939317_42 - - - - 0.0000000000000000000004307 98.0
HFD2_k127_1939317_44 AhpC/TSA family - - - 0.00000000000000000001118 100.0
HFD2_k127_1939317_45 indolepyruvate ferredoxin oxidoreductase beta subunit K00180 - 1.2.7.8 0.00000000000000000001745 107.0
HFD2_k127_1939317_46 - - - - 0.000000000000000008779 95.0
HFD2_k127_1939317_48 Protein of unknown function, DUF393 - - - 0.000000000000009413 79.0
HFD2_k127_1939317_49 Late embryogenesis abundant protein - - - 0.00000000003351 77.0
HFD2_k127_1939317_5 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 579.0
HFD2_k127_1939317_51 - - - - 0.0000000003617 63.0
HFD2_k127_1939317_52 Gram-negative-bacterium-type cell outer membrane assembly - - - 0.00004033 54.0
HFD2_k127_1939317_53 Histidine kinase - - - 0.0000411 52.0
HFD2_k127_1939317_6 Thiolase, C-terminal domain K00626,K07508 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 569.0
HFD2_k127_1939317_7 PDZ DHR GLGF domain protein K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007267 539.0
HFD2_k127_1939317_8 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282,K18008 - 1.12.2.1,1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 503.0
HFD2_k127_1939317_9 Mediates influx of magnesium ions K03284,K16074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 482.0
HFD2_k127_1940655_0 DNA polymerase K02337,K14162 - 2.7.7.7 0.0 1870.0
HFD2_k127_1940655_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 1.879e-255 806.0
HFD2_k127_1940655_2 Mycolic acid cyclopropane synthetase K00574,K20238 - 2.1.1.317,2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009503 540.0
HFD2_k127_1940655_3 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 464.0
HFD2_k127_1940655_4 Helix-hairpin-helix class 2 (Pol1 family) motifs - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 427.0
HFD2_k127_1940655_5 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 367.0
HFD2_k127_1940655_6 spore germination - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007799 267.0
HFD2_k127_1940655_7 - - - - 0.00000000000000000000000000000000000000000000000009854 181.0
HFD2_k127_1940655_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000007078 160.0
HFD2_k127_1981729_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1410.0
HFD2_k127_1981729_1 asparaginyl-tRNA synthetase K01893 - 6.1.1.22 4.751e-257 801.0
HFD2_k127_1981729_10 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009927 383.0
HFD2_k127_1981729_11 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006391 381.0
HFD2_k127_1981729_12 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005279 332.0
HFD2_k127_1981729_13 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 326.0
HFD2_k127_1981729_14 riboflavin synthase, alpha K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009025 314.0
HFD2_k127_1981729_15 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000003093 226.0
HFD2_k127_1981729_16 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000001778 243.0
HFD2_k127_1981729_17 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000795 220.0
HFD2_k127_1981729_18 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000000000000000000000000001568 212.0
HFD2_k127_1981729_2 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 6.836e-227 708.0
HFD2_k127_1981729_20 Chemotaxis protein CheY K03413 - - 0.000000000000000000000000000000000001771 143.0
HFD2_k127_1981729_21 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000000000000000004489 123.0
HFD2_k127_1981729_22 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.000000000000000000000000000004669 132.0
HFD2_k127_1981729_24 MazG nucleotide pyrophosphohydrolase domain K02499,K04765 - 3.6.1.9 0.000000000000000000003022 94.0
HFD2_k127_1981729_25 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000000002244 85.0
HFD2_k127_1981729_3 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 1.213e-224 711.0
HFD2_k127_1981729_4 - - - - 3.667e-220 693.0
HFD2_k127_1981729_5 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 1.621e-207 657.0
HFD2_k127_1981729_6 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 608.0
HFD2_k127_1981729_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006061 520.0
HFD2_k127_1981729_8 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004431 483.0
HFD2_k127_1981729_9 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 451.0
HFD2_k127_2008987_0 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006814 435.0
HFD2_k127_2008987_1 repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 411.0
HFD2_k127_2008987_2 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007983 342.0
HFD2_k127_2008987_3 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004872 248.0
HFD2_k127_2008987_4 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000000000000000000000000000006579 217.0
HFD2_k127_2008987_5 chromosome segregation K03497 - - 0.000000000000000000000000000000000000000000000000000000000000478 214.0
HFD2_k127_2008987_6 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000000000000000000000000000000000000000000000000004274 199.0
HFD2_k127_2198351_0 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 598.0
HFD2_k127_2198351_1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.000000000000000000000000000000000000009185 148.0
HFD2_k127_2245014_0 Oligoendopeptidase f - - - 7.608e-267 848.0
HFD2_k127_2245014_1 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 554.0
HFD2_k127_2245014_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003241 409.0
HFD2_k127_2245014_3 Universal stress protein - - - 0.00000000000000000000001103 114.0
HFD2_k127_2245189_0 FAD linked oxidase domain protein - - - 0.0 1620.0
HFD2_k127_2245189_1 Pyruvate flavodoxin ferredoxin K00174 - 1.2.7.11,1.2.7.3 1.791e-273 853.0
HFD2_k127_2245189_2 aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 1.677e-194 620.0
HFD2_k127_2245189_3 [isocitrate dehydrogenase (NADP+)] phosphatase activity K00906 GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004721,GO:0004722,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009060,GO:0009987,GO:0015980,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0016999,GO:0017076,GO:0017144,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046487,GO:0050790,GO:0055114,GO:0065007,GO:0065009,GO:0070262,GO:0071704,GO:0072350,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 607.0
HFD2_k127_2245189_4 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 546.0
HFD2_k127_2245189_5 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 415.0
HFD2_k127_2245189_6 radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006977 346.0
HFD2_k127_2245189_7 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009828 277.0
HFD2_k127_2245189_8 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001624 284.0
HFD2_k127_2245189_9 Thioesterase superfamily K02614 - - 0.00000000000000000000000000002564 123.0
HFD2_k127_2267558_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 3.962e-318 985.0
HFD2_k127_2267558_1 OPT oligopeptide transporter protein - - - 1.227e-308 960.0
HFD2_k127_2267558_10 - - - - 2.012e-207 655.0
HFD2_k127_2267558_11 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 5.586e-198 635.0
HFD2_k127_2267558_12 Pfam:DUF955 K07110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 586.0
HFD2_k127_2267558_13 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 550.0
HFD2_k127_2267558_14 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 542.0
HFD2_k127_2267558_15 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970,K00974 - 2.7.7.19,2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003479 540.0
HFD2_k127_2267558_16 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 540.0
HFD2_k127_2267558_17 PFAM transglutaminase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004684 493.0
HFD2_k127_2267558_18 OPT oligopeptide transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 503.0
HFD2_k127_2267558_19 NAD(P)H quinone oxidoreductase, PIG3 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005105 481.0
HFD2_k127_2267558_2 Ribulose bisphosphate carboxylase large chain, catalytic domain - - - 1.156e-267 831.0
HFD2_k127_2267558_20 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 469.0
HFD2_k127_2267558_21 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000645 479.0
HFD2_k127_2267558_22 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K01086,K03841 - 3.1.3.11,3.1.3.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 492.0
HFD2_k127_2267558_23 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01885,K01894 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 445.0
HFD2_k127_2267558_24 Belongs to the arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003299 447.0
HFD2_k127_2267558_25 stage V sporulation protein K - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009351 424.0
HFD2_k127_2267558_26 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009075 422.0
HFD2_k127_2267558_27 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 405.0
HFD2_k127_2267558_28 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 340.0
HFD2_k127_2267558_29 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 330.0
HFD2_k127_2267558_3 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 1.03e-256 809.0
HFD2_k127_2267558_30 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 319.0
HFD2_k127_2267558_31 Formamidopyrimidine-DNA glycosylase N-terminal domain K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005974 328.0
HFD2_k127_2267558_33 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001072 279.0
HFD2_k127_2267558_34 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000001051 265.0
HFD2_k127_2267558_35 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002499 281.0
HFD2_k127_2267558_36 Domain of unknown function (DUF2437) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001653 252.0
HFD2_k127_2267558_37 Glyoxalase-like domain K05606 - 5.1.99.1 0.0000000000000000000000000000000000000000000000000000000000000000002247 231.0
HFD2_k127_2267558_38 iron ion homeostasis K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000005803 242.0
HFD2_k127_2267558_39 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000005103 236.0
HFD2_k127_2267558_4 Multicopper oxidase K08100 - 1.3.3.5 5.548e-246 780.0
HFD2_k127_2267558_40 Efflux ABC transporter, permease protein K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000003075 240.0
HFD2_k127_2267558_41 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000000000000005178 220.0
HFD2_k127_2267558_42 Ribulose bisphosphate carboxylase, small chain K01602 - 4.1.1.39 0.0000000000000000000000000000000000000000000000000001618 208.0
HFD2_k127_2267558_43 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000006472 191.0
HFD2_k127_2267558_44 response regulator K03654 - 3.6.4.12 0.000000000000000000000000000000000000000000000009722 177.0
HFD2_k127_2267558_45 OsmC-like protein K09136 - - 0.0000000000000000000000000000000000000000000002719 190.0
HFD2_k127_2267558_46 peroxiredoxin activity K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.00000000000000000000000000000000000009389 143.0
HFD2_k127_2267558_48 phosphohistidine phosphatase, SixA K08296 - - 0.00000000000000000000000000000002163 145.0
HFD2_k127_2267558_5 Malate synthase K01638 - 2.3.3.9 4.186e-242 760.0
HFD2_k127_2267558_53 - - - - 0.00000000000000000001826 99.0
HFD2_k127_2267558_54 Protein of unknown function (DUF2723) - - - 0.0000000000000000001024 102.0
HFD2_k127_2267558_55 PFAM Tetratricopeptide repeat - - - 0.0000000000002334 83.0
HFD2_k127_2267558_56 PFAM AhpC TSA family K03564 - 1.11.1.15 0.000000003432 67.0
HFD2_k127_2267558_57 - - - - 0.00000001223 65.0
HFD2_k127_2267558_58 Di-haem oxidoreductase, putative peroxidase - - - 0.00000001857 66.0
HFD2_k127_2267558_59 Outer membrane protein beta-barrel domain - - - 0.00000006166 63.0
HFD2_k127_2267558_6 ATPase family associated with various cellular activities (AAA) K06027 - 3.6.4.6 1.432e-233 737.0
HFD2_k127_2267558_61 Protein of unknown function (DUF1257) - - - 0.000005261 53.0
HFD2_k127_2267558_62 Protein of unknown function (DUF2997) - - - 0.000006658 50.0
HFD2_k127_2267558_64 Protein of unknown function (DUF1298) - - - 0.0009052 47.0
HFD2_k127_2267558_7 secondary active sulfate transmembrane transporter activity K06901 - - 4.409e-216 687.0
HFD2_k127_2267558_8 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 7.874e-214 686.0
HFD2_k127_2267558_9 4-alpha-glucanotransferase K00705 - 2.4.1.25 3.925e-209 678.0
HFD2_k127_2273147_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.111e-275 865.0
HFD2_k127_2273147_1 Sarcosine oxidase K00303 - 1.5.3.1 1.709e-227 730.0
HFD2_k127_2273147_10 Conserved repeat domain K02024,K02343,K03407,K06182,K08372,K12065,K16291 - 2.7.13.3,2.7.7.7,5.4.99.21 0.00000000006054 76.0
HFD2_k127_2273147_2 pseudouridine synthase activity K06176 - 5.4.99.27 2.367e-195 621.0
HFD2_k127_2273147_3 Periplasmic protein TonB links inner and outer membranes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005771 570.0
HFD2_k127_2273147_4 2Fe-2S iron-sulfur cluster binding domain K00302 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005751 493.0
HFD2_k127_2273147_5 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 378.0
HFD2_k127_2273147_6 PFAM PHP domain K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 346.0
HFD2_k127_2273147_9 PilZ domain - - - 0.0000000000000000002056 93.0
HFD2_k127_230331_0 Metallophosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001704 291.0
HFD2_k127_230331_1 PFAM Cytochrome c, class I - - - 0.00000000000000000000000000000000000000000000001071 175.0
HFD2_k127_230331_2 PFAM cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.00000000000000000000000005581 110.0
HFD2_k127_230331_3 ECF sigma factor K03088 - - 0.0000000000000000144 90.0
HFD2_k127_2374983_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 5.464e-303 952.0
HFD2_k127_2374983_1 Angiotensin-converting enzyme K01283 - 3.4.15.1 1.091e-278 869.0
HFD2_k127_2374983_10 Radical SAM superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 565.0
HFD2_k127_2374983_11 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008162 523.0
HFD2_k127_2374983_12 PFAM V-type ATPase 116 kDa K02123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006034 544.0
HFD2_k127_2374983_13 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity K12583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004674 522.0
HFD2_k127_2374983_14 regulation of microtubule-based process K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 455.0
HFD2_k127_2374983_15 Glycosyl transferase family 21 K00720 - 2.4.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 453.0
HFD2_k127_2374983_16 Dienelactone hydrolase family K07100 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004559 440.0
HFD2_k127_2374983_17 Trypsin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 383.0
HFD2_k127_2374983_18 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 381.0
HFD2_k127_2374983_19 Pirin K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005411 371.0
HFD2_k127_2374983_2 - - - - 3.265e-271 866.0
HFD2_k127_2374983_20 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006862 340.0
HFD2_k127_2374983_21 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005458 327.0
HFD2_k127_2374983_22 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006521 343.0
HFD2_k127_2374983_23 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 316.0
HFD2_k127_2374983_24 Sir2 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 303.0
HFD2_k127_2374983_25 Belongs to the ribose-phosphate pyrophosphokinase family K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008148 300.0
HFD2_k127_2374983_26 TIGRFAM phosphate ABC transporter K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003903 274.0
HFD2_k127_2374983_27 Curli production assembly/transport component CsgG - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008514 270.0
HFD2_k127_2374983_28 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000003132 246.0
HFD2_k127_2374983_29 Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000000000000000002198 249.0
HFD2_k127_2374983_3 PFAM PHP domain protein K02347,K04477 - - 1.96e-251 788.0
HFD2_k127_2374983_30 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.0000000000000000000000000000000000000000000000000000000000000003231 246.0
HFD2_k127_2374983_31 PFAM Multicopper oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000002931 244.0
HFD2_k127_2374983_32 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000000000000000000000000000000000000000000001583 232.0
HFD2_k127_2374983_33 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 GO:0003674,GO:0003824,GO:0004422,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006188,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0052657,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.8 0.0000000000000000000000000000000000000000000000000005375 207.0
HFD2_k127_2374983_34 Tautomerase enzyme - - - 0.0000000000000000000000000000000003443 136.0
HFD2_k127_2374983_35 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.000000000000000000000000000000007296 130.0
HFD2_k127_2374983_37 Archease protein family (MTH1598/TM1083) - - - 0.000000000000000000000000004455 115.0
HFD2_k127_2374983_38 Transposase - - - 0.000000000000000000000000105 108.0
HFD2_k127_2374983_39 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.00000000000000000000006408 110.0
HFD2_k127_2374983_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 4.436e-247 797.0
HFD2_k127_2374983_40 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000005225 90.0
HFD2_k127_2374983_41 RibD C-terminal domain - - - 0.000000000000003992 76.0
HFD2_k127_2374983_42 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.000000000005106 77.0
HFD2_k127_2374983_43 cAMP biosynthetic process - - - 0.0001481 53.0
HFD2_k127_2374983_5 4Fe-4S dicluster domain - - - 2.585e-216 679.0
HFD2_k127_2374983_6 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 3.628e-213 694.0
HFD2_k127_2374983_7 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 1.406e-202 661.0
HFD2_k127_2374983_8 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 1.176e-195 624.0
HFD2_k127_2374983_9 histidine kinase A domain protein K07679 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 619.0
HFD2_k127_2478092_0 Polysaccharide biosynthesis protein K15894,K17716 - 4.2.1.115,5.1.3.2 9.306e-227 726.0
HFD2_k127_2478092_1 PFAM lipopolysaccharide biosynthesis protein K16692 - - 7.662e-200 648.0
HFD2_k127_2478092_2 Belongs to the DegT DnrJ EryC1 family K19430 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006788 590.0
HFD2_k127_2478092_3 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000003245 199.0
HFD2_k127_2540796_0 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.0 1123.0
HFD2_k127_2540796_1 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 1.109e-302 958.0
HFD2_k127_2540796_10 hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 488.0
HFD2_k127_2540796_11 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 423.0
HFD2_k127_2540796_12 Molydopterin dinucleotide binding domain K08352 - 1.8.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 443.0
HFD2_k127_2540796_13 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 404.0
HFD2_k127_2540796_14 Magnesium chelatase, subunit ChlI K03404,K03405 - 6.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 368.0
HFD2_k127_2540796_15 beta-keto acid cleavage enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000527 339.0
HFD2_k127_2540796_16 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003368 344.0
HFD2_k127_2540796_17 Nitronate monooxygenase K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 317.0
HFD2_k127_2540796_18 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006999 314.0
HFD2_k127_2540796_19 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004055 328.0
HFD2_k127_2540796_2 Acyl-CoA dehydrogenase, N-terminal domain - - - 1.317e-288 902.0
HFD2_k127_2540796_20 Major Facilitator Superfamily K08177 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000132 287.0
HFD2_k127_2540796_21 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000005476 245.0
HFD2_k127_2540796_22 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000005651 240.0
HFD2_k127_2540796_23 Cytochrome c K00413 - - 0.0000000000000000000000000000000000000000000000000000000000006616 240.0
HFD2_k127_2540796_24 von Willebrand factor (vWF) type A domain K03404,K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000495 201.0
HFD2_k127_2540796_25 Enoyl-CoA hydratase carnithine racemase K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000001854 190.0
HFD2_k127_2540796_26 PFAM peptidase M52 hydrogen uptake protein K03605 - - 0.000000000000000000000000000000000000000000003553 172.0
HFD2_k127_2540796_27 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000003989 169.0
HFD2_k127_2540796_28 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000002036 153.0
HFD2_k127_2540796_29 nickel cation binding K04651 - - 0.0000000000000000000000000000000000004036 154.0
HFD2_k127_2540796_3 carboxylase K01969,K13778 - 6.4.1.4,6.4.1.5 1.765e-232 752.0
HFD2_k127_2540796_30 ABC transporter K02049 - - 0.0000000000000000000000000000000005952 149.0
HFD2_k127_2540796_31 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000001414 132.0
HFD2_k127_2540796_32 carbon dioxide binding K04653,K04654 - - 0.00000000000000000000000000000001535 142.0
HFD2_k127_2540796_33 NMT1-like family K02051,K15553 - - 0.000000000000000000000000000000125 142.0
HFD2_k127_2540796_34 Acyl-CoA dehydrogenase type 2 domain - - - 0.0000000000000000000000009482 123.0
HFD2_k127_2540796_35 Alpha/beta hydrolase family - - - 0.0000000000000000000001592 107.0
HFD2_k127_2540796_36 DnaJ molecular chaperone homology domain - - - 0.000000000000001714 90.0
HFD2_k127_2540796_37 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000001072 77.0
HFD2_k127_2540796_38 negative regulation of guanyl-nucleotide exchange factor activity K15837,K15839 GO:0000132,GO:0000139,GO:0000226,GO:0000278,GO:0001709,GO:0001965,GO:0003674,GO:0005092,GO:0005096,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005783,GO:0005789,GO:0005794,GO:0005829,GO:0005886,GO:0005938,GO:0006996,GO:0007010,GO:0007017,GO:0007049,GO:0007163,GO:0007275,GO:0007399,GO:0007400,GO:0007405,GO:0008047,GO:0008104,GO:0008150,GO:0008277,GO:0008283,GO:0008356,GO:0009893,GO:0009894,GO:0009896,GO:0009966,GO:0009987,GO:0010506,GO:0010508,GO:0010646,GO:0012505,GO:0014016,GO:0014017,GO:0016020,GO:0016043,GO:0016239,GO:0016241,GO:0017145,GO:0019222,GO:0019904,GO:0022008,GO:0022402,GO:0023051,GO:0030010,GO:0030154,GO:0030234,GO:0030695,GO:0031090,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0031974,GO:0031981,GO:0031984,GO:0032091,GO:0032501,GO:0032502,GO:0032991,GO:0033036,GO:0034260,GO:0036445,GO:0040001,GO:0042175,GO:0043085,GO:0043086,GO:0043087,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043393,GO:0043547,GO:0044092,GO:0044093,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044431,GO:0044432,GO:0044444,GO:0044446,GO:0044448,GO:0044464,GO:0045165,GO:0045167,GO:0045175,GO:0045177,GO:0045179,GO:0045185,GO:0048103,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048699,GO:0048731,GO:0048856,GO:0048863,GO:0048865,GO:0048867,GO:0048869,GO:0050789,GO:0050790,GO:0050794,GO:0050795,GO:0051098,GO:0051099,GO:0051100,GO:0051179,GO:0051234,GO:0051235,GO:0051293,GO:0051294,GO:0051301,GO:0051336,GO:0051345,GO:0051346,GO:0051640,GO:0051641,GO:0051649,GO:0051653,GO:0051656,GO:0055057,GO:0055059,GO:0060259,GO:0060589,GO:0061351,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0071840,GO:0071944,GO:0072089,GO:0098588,GO:0098722,GO:0098772,GO:0098791,GO:0098827,GO:0099568,GO:0099738,GO:1902850,GO:1903047,GO:1904424,GO:1905097,GO:1905098 - 0.0000000000005992 83.0
HFD2_k127_2540796_4 AMP-binding enzyme C-terminal domain K08295 - 6.2.1.32 8.091e-209 663.0
HFD2_k127_2540796_40 - - - - 0.00000001204 62.0
HFD2_k127_2540796_5 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000598 593.0
HFD2_k127_2540796_6 Belongs to the HypD family K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 527.0
HFD2_k127_2540796_7 PFAM acyl-CoA dehydrogenase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003974 524.0
HFD2_k127_2540796_8 PFAM Carbamoyl-phosphate synthase L chain K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 527.0
HFD2_k127_2540796_9 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 492.0
HFD2_k127_2597471_0 response regulator K07714 - - 2.03e-203 648.0
HFD2_k127_2597471_1 pilus assembly protein K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000511 552.0
HFD2_k127_2597471_10 Prokaryotic N-terminal methylation motif K02650 - - 0.0000000000000000000000000000000000000000000006363 177.0
HFD2_k127_2597471_11 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000007136 111.0
HFD2_k127_2597471_2 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 523.0
HFD2_k127_2597471_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006901 445.0
HFD2_k127_2597471_4 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 367.0
HFD2_k127_2597471_5 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 337.0
HFD2_k127_2597471_6 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000625 279.0
HFD2_k127_2597471_7 Type II secretion system (T2SS), protein M subtype b K02664 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008582 267.0
HFD2_k127_2597471_8 ABC-2 family transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001603 278.0
HFD2_k127_2597471_9 Fimbrial assembly protein (PilN) K02663 - - 0.00000000000000000000000000000000000000000000000000000000001131 228.0
HFD2_k127_2676332_0 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 443.0
HFD2_k127_2676332_1 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 0.000000000000000000000000000000000000002344 147.0
HFD2_k127_2676332_2 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000007173 144.0
HFD2_k127_2711834_0 Belongs to the SAICAR synthetase family K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 565.0
HFD2_k127_2711834_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 459.0
HFD2_k127_2711834_2 DNA-templated transcription, initiation K03088,K11333 - 1.3.7.14,1.3.7.15 0.00000000000000000000000000000000000000000000000000000002707 205.0
HFD2_k127_2711834_3 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 GO:0001510,GO:0002128,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016427,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052665,GO:0052666,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.200 0.0000000000000000000000000000000000000000000003296 170.0
HFD2_k127_2711834_5 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.000000000000000000000000000000006027 128.0
HFD2_k127_2711834_6 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 - 2.1.1.200 0.000000000000000000000001604 108.0
HFD2_k127_2716858_0 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008957 485.0
HFD2_k127_2716858_1 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.00000000000000000000000000000126 131.0
HFD2_k127_2716858_2 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000005184 94.0
HFD2_k127_2737918_0 Transcriptional regulator - - - 1.076e-268 837.0
HFD2_k127_2737918_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 494.0
HFD2_k127_2737918_3 endonuclease activity K07451 - - 0.00000000000000000000000000000000000000005207 160.0
HFD2_k127_2737918_4 endonuclease activity K07451 - - 0.000000000000000000001862 107.0
HFD2_k127_2746630_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1294.0
HFD2_k127_2746630_1 Formate dehydrogenase, alpha subunit K00123 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006464,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009326,GO:0009987,GO:0016043,GO:0016226,GO:0016491,GO:0016622,GO:0016903,GO:0018282,GO:0018289,GO:0018291,GO:0019538,GO:0022607,GO:0031163,GO:0032991,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0047111,GO:0051186,GO:0055114,GO:0071704,GO:0071840,GO:1901564,GO:1902494 1.17.1.9 0.0 1241.0
HFD2_k127_2746630_10 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 610.0
HFD2_k127_2746630_11 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 625.0
HFD2_k127_2746630_12 Benzoyl-CoA reductase subunit K04114 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 633.0
HFD2_k127_2746630_13 C-terminal AAA-associated domain K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004917 599.0
HFD2_k127_2746630_14 Acyl-CoA dehydrogenase, middle domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009125 587.0
HFD2_k127_2746630_15 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000393 607.0
HFD2_k127_2746630_16 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002818 572.0
HFD2_k127_2746630_17 Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000029 559.0
HFD2_k127_2746630_18 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07538 - 1.1.1.368 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 530.0
HFD2_k127_2746630_19 Di-haem oxidoreductase, putative peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005947 529.0
HFD2_k127_2746630_2 CoA binding domain K09181 - - 1.817e-311 979.0
HFD2_k127_2746630_20 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 526.0
HFD2_k127_2746630_21 Long-chain fatty acid--CoA ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 529.0
HFD2_k127_2746630_22 Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000648 469.0
HFD2_k127_2746630_23 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 444.0
HFD2_k127_2746630_24 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 452.0
HFD2_k127_2746630_25 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 426.0
HFD2_k127_2746630_26 Formate dehydrogenase N, transmembrane K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 415.0
HFD2_k127_2746630_27 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 450.0
HFD2_k127_2746630_28 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 421.0
HFD2_k127_2746630_29 Aminoglycoside phosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 427.0
HFD2_k127_2746630_3 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K07516 - 1.1.1.35 4.417e-301 975.0
HFD2_k127_2746630_30 BadF/BadG/BcrA/BcrD ATPase family K04115 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 396.0
HFD2_k127_2746630_31 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007613 372.0
HFD2_k127_2746630_32 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009294 378.0
HFD2_k127_2746630_33 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 361.0
HFD2_k127_2746630_34 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate K00019 - 1.1.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 352.0
HFD2_k127_2746630_35 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 335.0
HFD2_k127_2746630_36 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 315.0
HFD2_k127_2746630_37 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 336.0
HFD2_k127_2746630_38 copper resistance - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 327.0
HFD2_k127_2746630_39 Alpha beta hydrolase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003776 342.0
HFD2_k127_2746630_4 Binding-protein-dependent transport system inner membrane component K02050 - - 7.274e-244 767.0
HFD2_k127_2746630_40 PFAM Extracellular ligand-binding receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006717 312.0
HFD2_k127_2746630_41 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007714 281.0
HFD2_k127_2746630_42 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000295 267.0
HFD2_k127_2746630_43 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008529 271.0
HFD2_k127_2746630_44 formate dehydrogenase K00127 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002726 261.0
HFD2_k127_2746630_45 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001013 274.0
HFD2_k127_2746630_46 enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001145 251.0
HFD2_k127_2746630_47 PFAM ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000007015 248.0
HFD2_k127_2746630_48 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000001178 233.0
HFD2_k127_2746630_49 Biotin-lipoyl like - - - 0.00000000000000000000000000000000000000000000000000000000000002232 243.0
HFD2_k127_2746630_5 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 1.774e-228 733.0
HFD2_k127_2746630_50 COG0559 Branched-chain amino acid ABC-type transport system, permease components K01997 - - 0.00000000000000000000000000000000000000000000000000000000007706 216.0
HFD2_k127_2746630_51 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000168 214.0
HFD2_k127_2746630_52 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000001348 204.0
HFD2_k127_2746630_53 extracellular matrix structural constituent - - - 0.00000000000000000000000000000000000000000000000000009552 216.0
HFD2_k127_2746630_54 Necessary for formate dehydrogenase activity K02380 - - 0.0000000000000000000000000000000000000000000000000005713 203.0
HFD2_k127_2746630_55 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000001326 196.0
HFD2_k127_2746630_56 PFAM amino acid-binding ACT domain protein - - - 0.0000000000000000000000000000000000000000000000007447 177.0
HFD2_k127_2746630_57 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000000000000000000000000000000000001084 175.0
HFD2_k127_2746630_58 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000001604 194.0
HFD2_k127_2746630_59 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000779 162.0
HFD2_k127_2746630_6 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 3.285e-220 696.0
HFD2_k127_2746630_60 Polysaccharide lyase family 4, domain II - - - 0.00000000000000000000000000000000000001849 154.0
HFD2_k127_2746630_61 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.000000000000000000000000000000007261 131.0
HFD2_k127_2746630_62 Thioesterase superfamily protein - - - 0.000000000000000000000000000000008284 131.0
HFD2_k127_2746630_63 cytochrome c - - - 0.00000000000000000000000000003942 124.0
HFD2_k127_2746630_64 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.000000000000000000000001775 119.0
HFD2_k127_2746630_65 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000003944 108.0
HFD2_k127_2746630_66 Transmembrane anti-sigma factor - - - 0.0000000000000000001897 98.0
HFD2_k127_2746630_67 Serine hydrolase K07002 - - 0.000000000000002689 76.0
HFD2_k127_2746630_68 diguanylate cyclase - - - 0.00000000004141 76.0
HFD2_k127_2746630_69 Protein of unknown function (DUF3341) - - - 0.0000000003796 70.0
HFD2_k127_2746630_7 acyl-CoA dehydrogenase K00252 - 1.3.8.6 1.383e-200 630.0
HFD2_k127_2746630_8 Periplasmic binding protein domain K01999 - - 5.86e-196 617.0
HFD2_k127_2746630_9 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000583 613.0
HFD2_k127_2776817_0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0 2030.0
HFD2_k127_2776817_1 Cytochrome c554 and c-prime - - - 7.129e-252 786.0
HFD2_k127_2776817_10 retrograde transport, endosome to Golgi K07095 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009954 468.0
HFD2_k127_2776817_11 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005096 412.0
HFD2_k127_2776817_12 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 439.0
HFD2_k127_2776817_13 Acetamidase/Formamidase family K01455 - 3.5.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005195 415.0
HFD2_k127_2776817_14 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 406.0
HFD2_k127_2776817_15 geranylgeranyl reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 377.0
HFD2_k127_2776817_16 chlorophyll binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004086 357.0
HFD2_k127_2776817_17 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 325.0
HFD2_k127_2776817_18 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 303.0
HFD2_k127_2776817_19 cytochrome p450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001068 310.0
HFD2_k127_2776817_2 Pyridoxal-phosphate dependent enzyme K01697,K01738 - 2.5.1.47,4.2.1.22 5.883e-215 677.0
HFD2_k127_2776817_20 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00375,K05825,K16422,K16423 - 1.1.3.46,2.6.1.103 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005116 301.0
HFD2_k127_2776817_21 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001521 291.0
HFD2_k127_2776817_22 DNA alkylation repair enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004729 267.0
HFD2_k127_2776817_23 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006066 259.0
HFD2_k127_2776817_24 lipoprotein transporter activity K02003,K09814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002595 254.0
HFD2_k127_2776817_25 chlorophyll binding - - - 0.0000000000000000000000000000000000000000000000000000000000000008417 228.0
HFD2_k127_2776817_26 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000002323 221.0
HFD2_k127_2776817_27 HupE / UreJ protein - - - 0.0000000000000000000000000000000000000000000000000000000000003781 224.0
HFD2_k127_2776817_28 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000005993 217.0
HFD2_k127_2776817_29 NAD(P)H-binding - - - 0.000000000000000000000000000000000000000000000000000000005159 205.0
HFD2_k127_2776817_3 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 7.437e-215 688.0
HFD2_k127_2776817_30 GMC family oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000008626 224.0
HFD2_k127_2776817_31 YCII-related domain - - - 0.000000000000000000000000000000000000000000000000001134 208.0
HFD2_k127_2776817_32 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000000002438 175.0
HFD2_k127_2776817_33 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000005125 183.0
HFD2_k127_2776817_34 Adenylylsulfate kinase K00860 - 2.7.1.25 0.000000000000000000000000000000000000000000002033 183.0
HFD2_k127_2776817_35 DNA-templated transcription, initiation K03088,K11333 - 1.3.7.14,1.3.7.15 0.00000000000000000000000000000000000000002339 159.0
HFD2_k127_2776817_36 Protein of unknown function (DUF456) K09793 - - 0.00000000000000000000000000000000000000005943 164.0
HFD2_k127_2776817_37 ATPase. Has a role at an early stage in the morphogenesis of the spore coat - - - 0.0000000000000000000000000000000000000001484 169.0
HFD2_k127_2776817_38 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.0000000000000000000000000000000000000001898 171.0
HFD2_k127_2776817_4 Serine Threonine protein kinase K12132 - 2.7.11.1 9.769e-215 706.0
HFD2_k127_2776817_40 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.00000000000000000000000000009705 123.0
HFD2_k127_2776817_43 CHRD domain - - - 0.000000000000000000000003443 109.0
HFD2_k127_2776817_44 - - - - 0.00000000000000000000003166 106.0
HFD2_k127_2776817_45 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000001264 92.0
HFD2_k127_2776817_47 - - - - 0.0000000000007855 82.0
HFD2_k127_2776817_48 - - - - 0.00000001452 64.0
HFD2_k127_2776817_49 - - - - 0.0000005142 62.0
HFD2_k127_2776817_5 Vitamin K epoxide reductase family - - - 6.659e-208 659.0
HFD2_k127_2776817_50 Si ch211-127i16.2 K00274 - 1.4.3.4 0.0001496 57.0
HFD2_k127_2776817_6 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 575.0
HFD2_k127_2776817_7 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000647 458.0
HFD2_k127_2776817_8 alcohol dehydrogenase K13953,K18382 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 452.0
HFD2_k127_2776817_9 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 429.0
HFD2_k127_2778332_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 2.342e-303 935.0
HFD2_k127_2778332_1 Short chain dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009986 342.0
HFD2_k127_2778332_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000001086 221.0
HFD2_k127_2778332_11 ABC-type uncharacterized transport system K01992 - - 0.000000000000000000000000000000000000000000000000000000000001491 224.0
HFD2_k127_2778332_12 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000362 204.0
HFD2_k127_2778332_13 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.000000000000000000000000000000000000000000000007673 173.0
HFD2_k127_2778332_14 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000003351 183.0
HFD2_k127_2778332_15 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000000000000000000003621 156.0
HFD2_k127_2778332_16 Domain of unknown function (DUF4340) - - - 0.0000000000000000000000000000000001131 149.0
HFD2_k127_2778332_18 Protein of unknown function (DUF2892) - - - 0.00000000000000002039 89.0
HFD2_k127_2778332_2 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 333.0
HFD2_k127_2778332_3 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009707 295.0
HFD2_k127_2778332_4 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 296.0
HFD2_k127_2778332_5 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001368 271.0
HFD2_k127_2778332_6 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000001049 252.0
HFD2_k127_2778332_7 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001404 253.0
HFD2_k127_2778332_8 23S rRNA (guanine(2445)-N(2))-methyltransferase activity K21515 - 2.1.1.209 0.0000000000000000000000000000000000000000000000000000000000000000000009531 248.0
HFD2_k127_2778332_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000002629 242.0
HFD2_k127_2838503_0 Putative modulator of DNA gyrase K03568 - - 1.534e-243 762.0
HFD2_k127_2838503_1 Putative modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 588.0
HFD2_k127_2838503_2 Cellulose biosynthesis protein BcsQ K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007242 465.0
HFD2_k127_2838503_3 CBS domain containing protein K06189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 460.0
HFD2_k127_2838503_4 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 477.0
HFD2_k127_2838503_5 deoxyhypusine monooxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 360.0
HFD2_k127_2838503_6 DUF3160 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004113 267.0
HFD2_k127_2838503_7 nuclear chromosome segregation K13582,K21471 - - 0.0000000000000000000000000000000000000000000000000000000000000001094 233.0
HFD2_k127_2838503_8 hydrolase of the alpha beta superfamily K07018 - - 0.00000000000000000000000000000000000000000000000000000000000007368 238.0
HFD2_k127_2848980_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1420.0
HFD2_k127_2848980_1 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.0 1113.0
HFD2_k127_2848980_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 520.0
HFD2_k127_2848980_11 MoeA C-terminal region (domain IV) K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004589 482.0
HFD2_k127_2848980_12 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 481.0
HFD2_k127_2848980_13 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009036 405.0
HFD2_k127_2848980_14 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 424.0
HFD2_k127_2848980_15 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 328.0
HFD2_k127_2848980_16 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000545 284.0
HFD2_k127_2848980_17 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005222 280.0
HFD2_k127_2848980_18 Response regulator receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009521 280.0
HFD2_k127_2848980_19 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005221 282.0
HFD2_k127_2848980_2 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 5.839e-314 987.0
HFD2_k127_2848980_20 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002558 258.0
HFD2_k127_2848980_21 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000001872 242.0
HFD2_k127_2848980_22 chemotaxis K03408 - - 0.0000000000000000000000000000000000000000000000000000000000003131 220.0
HFD2_k127_2848980_23 PFAM CBS domain containing protein K04767 - - 0.000000000000000000000000000000000000000000000000000006505 194.0
HFD2_k127_2848980_24 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.000000000000000000000000000000000000000000000004194 181.0
HFD2_k127_2848980_25 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000005062 169.0
HFD2_k127_2848980_26 Haemolysin secretion/activation protein ShlB/FhaC/HecB - - - 0.0000000000000000000000000000000000000002158 167.0
HFD2_k127_2848980_28 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000351 135.0
HFD2_k127_2848980_29 sequence-specific DNA binding - - - 0.000000000000000000000000002263 114.0
HFD2_k127_2848980_3 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 8.511e-287 921.0
HFD2_k127_2848980_31 Psort location CytoplasmicMembrane, score - - - 0.0000000004025 65.0
HFD2_k127_2848980_4 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 3.522e-274 854.0
HFD2_k127_2848980_5 protein containing caspase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 634.0
HFD2_k127_2848980_6 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006544 627.0
HFD2_k127_2848980_7 Protein of unknown function (DUF1343) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006246 601.0
HFD2_k127_2848980_8 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008316 590.0
HFD2_k127_2848980_9 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 565.0
HFD2_k127_2852263_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 3.855e-280 868.0
HFD2_k127_2852263_1 Mitochondrial biogenesis AIM24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 403.0
HFD2_k127_2852263_10 - - - - 0.000000000000000000000000002347 115.0
HFD2_k127_2852263_11 Histidine kinase - - - 0.0000000000000000001628 100.0
HFD2_k127_2852263_12 Protein of unknown function (DUF2867) - - - 0.0000000000000000192 89.0
HFD2_k127_2852263_13 - - - - 0.0000000000002592 82.0
HFD2_k127_2852263_14 chromosome segregation K03497 - - 0.0000000001219 64.0
HFD2_k127_2852263_15 - - - - 0.0000008834 50.0
HFD2_k127_2852263_2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 293.0
HFD2_k127_2852263_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009508 294.0
HFD2_k127_2852263_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001099 276.0
HFD2_k127_2852263_5 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007931 263.0
HFD2_k127_2852263_6 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000006278 216.0
HFD2_k127_2852263_7 Transglycosylase K08309 - - 0.0000000000000000000000000000000000000000000000001318 188.0
HFD2_k127_2852263_8 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000007731 162.0
HFD2_k127_2852263_9 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000001165 130.0
HFD2_k127_2876718_0 Histone deacetylase domain - - - 2.202e-237 746.0
HFD2_k127_2876718_1 Type II IV secretion system protein K02283,K03609 - - 3.005e-203 640.0
HFD2_k127_2876718_10 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000000008158 180.0
HFD2_k127_2876718_11 TPR repeat - - - 0.0000000000000000000000000000000000000002862 174.0
HFD2_k127_2876718_12 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000000000000000001323 145.0
HFD2_k127_2876718_14 TadE-like protein - - - 0.0000000002459 72.0
HFD2_k127_2876718_15 peptidase K02278 - 3.4.23.43 0.00000005193 63.0
HFD2_k127_2876718_17 Flp pilus assembly protein, pilin Flp K02651 - - 0.00001248 50.0
HFD2_k127_2876718_2 Belongs to the GSP D family K02280 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 562.0
HFD2_k127_2876718_3 Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 355.0
HFD2_k127_2876718_4 Response regulator, receiver K02282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004197 347.0
HFD2_k127_2876718_5 8 heme-binding sites - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005459 335.0
HFD2_k127_2876718_6 PFAM type II secretion system K12510 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 307.0
HFD2_k127_2876718_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 296.0
HFD2_k127_2876718_8 TIGRFAM Flp pilus assembly protein CpaB K02279 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004043 286.0
HFD2_k127_2876718_9 PFAM type II secretion system K12511 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008163 265.0
HFD2_k127_2887843_0 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 414.0
HFD2_k127_2887843_1 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005811 328.0
HFD2_k127_2887843_2 PrkA AAA domain K07180 - - 0.0000000000000000000000000000000000000000000000000000000000004613 231.0
HFD2_k127_2887843_3 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000000000000000000000000003518 196.0
HFD2_k127_2887843_4 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000001268 147.0
HFD2_k127_2887843_5 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000000000000000000002163 138.0
HFD2_k127_2887843_6 Cold shock protein K03704 - - 0.000000000000000000000000000000002827 131.0
HFD2_k127_2887843_9 MacB-like periplasmic core domain K02004 - - 0.0000000000000000005656 93.0
HFD2_k127_2918046_0 PFAM Three-deoxy-D-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 6.031e-204 641.0
HFD2_k127_2918046_1 transferase activity, transferring glycosyl groups K00754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006461 456.0
HFD2_k127_2918046_10 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000001105 178.0
HFD2_k127_2918046_11 - - - - 0.00000000000000000000000000000000000003082 145.0
HFD2_k127_2918046_12 - - - - 0.0000000000000000000000000818 108.0
HFD2_k127_2918046_13 - - - - 0.000000000000000000002095 94.0
HFD2_k127_2918046_14 Belongs to the UPF0434 family K09791 - - 0.0000000000004564 81.0
HFD2_k127_2918046_15 - - - - 0.0000000000005699 74.0
HFD2_k127_2918046_16 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000003487 59.0
HFD2_k127_2918046_2 PFAM glycosyl transferase family 9 K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 447.0
HFD2_k127_2918046_3 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 410.0
HFD2_k127_2918046_4 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 410.0
HFD2_k127_2918046_5 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 371.0
HFD2_k127_2918046_6 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002506 366.0
HFD2_k127_2918046_7 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000002636 267.0
HFD2_k127_2918046_8 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.000000000000000000000000000000000000000000000000000000000000000005047 241.0
HFD2_k127_2918046_9 ABC transporter transmembrane region K06147,K18890 - - 0.000000000000000000000000000000000000000000000000000000000000000009922 227.0
HFD2_k127_2964089_0 Domain of unknown function (DUF4175) - - - 1.485e-272 876.0
HFD2_k127_2964089_1 Aerotolerance regulator N-terminal - - - 2.863e-256 814.0
HFD2_k127_2964089_2 CoA-binding domain - - - 2.315e-214 683.0
HFD2_k127_2964089_3 ATPase associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 526.0
HFD2_k127_2964089_4 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000653 565.0
HFD2_k127_2964089_5 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005716 403.0
HFD2_k127_2964089_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007796 302.0
HFD2_k127_2964089_7 PIN domain - - - 0.000000000000000000000000000000000000000000000000000000000000006072 223.0
HFD2_k127_3045352_0 glutamine synthetase K01915 - 6.3.1.2 4.326e-292 902.0
HFD2_k127_3045352_1 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004819 557.0
HFD2_k127_3045352_10 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004137 372.0
HFD2_k127_3045352_11 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004591 352.0
HFD2_k127_3045352_12 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002755 351.0
HFD2_k127_3045352_13 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008663 305.0
HFD2_k127_3045352_14 Metallopeptidase family M24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002563 272.0
HFD2_k127_3045352_15 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000000000000000177 203.0
HFD2_k127_3045352_17 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000009004 164.0
HFD2_k127_3045352_18 PFAM Excinuclease ABC, C subunit domain protein K07461 - - 0.00000000000000000000000000009757 121.0
HFD2_k127_3045352_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009511 546.0
HFD2_k127_3045352_3 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008606 482.0
HFD2_k127_3045352_4 PFAM ATP-binding region, ATPase domain protein K02668,K07708,K07709 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000393 473.0
HFD2_k127_3045352_5 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 464.0
HFD2_k127_3045352_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008222 438.0
HFD2_k127_3045352_7 amino acid ABC transporter, ATP-binding protein K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000971 401.0
HFD2_k127_3045352_8 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 404.0
HFD2_k127_3045352_9 Two component, sigma54 specific, transcriptional regulator, Fis family K07712,K07714 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005312 407.0
HFD2_k127_3050884_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000488 544.0
HFD2_k127_3050884_1 DNA-dependent DNA replication K02315,K04076 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 338.0
HFD2_k127_3050884_2 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 343.0
HFD2_k127_3050884_3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 338.0
HFD2_k127_3050884_4 Cytidylyltransferase family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008682 287.0
HFD2_k127_3050884_5 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000006524 278.0
HFD2_k127_3050884_6 Peptidase family M50 K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000006019 229.0
HFD2_k127_3066118_0 Belongs to the FtsK SpoIIIE SftA family K03466 - - 4.26e-321 1012.0
HFD2_k127_3066118_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.46e-315 971.0
HFD2_k127_3066118_10 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 484.0
HFD2_k127_3066118_11 DAHP synthetase I family K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006642 440.0
HFD2_k127_3066118_12 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 440.0
HFD2_k127_3066118_13 PFAM ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 387.0
HFD2_k127_3066118_14 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 378.0
HFD2_k127_3066118_15 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005726 366.0
HFD2_k127_3066118_16 PFAM Inward rectifier potassium channel K08715 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 313.0
HFD2_k127_3066118_17 Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA K00556 - 2.1.1.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 327.0
HFD2_k127_3066118_18 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005421 299.0
HFD2_k127_3066118_19 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000526 299.0
HFD2_k127_3066118_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 5.747e-280 865.0
HFD2_k127_3066118_21 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001882 258.0
HFD2_k127_3066118_22 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000002921 245.0
HFD2_k127_3066118_23 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000000000000000000000001326 263.0
HFD2_k127_3066118_24 zinc-ribbon domain - - - 0.00000000000000000000000000000000000000000000000000000000679 220.0
HFD2_k127_3066118_25 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000003588 194.0
HFD2_k127_3066118_26 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000000000000000000000000000000001556 190.0
HFD2_k127_3066118_27 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000001572 181.0
HFD2_k127_3066118_28 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.000000000000000000000000000000000000007561 146.0
HFD2_k127_3066118_29 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000000000000002362 140.0
HFD2_k127_3066118_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00334,K00335 - 1.6.5.3 4.886e-236 743.0
HFD2_k127_3066118_30 Transcription factor zinc-finger K09981 - - 0.00000000000000000000000000000000009746 152.0
HFD2_k127_3066118_31 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000002303 129.0
HFD2_k127_3066118_32 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000000000002631 121.0
HFD2_k127_3066118_33 lipopolysaccharide transport K09774 - - 0.0000000000000000000000000001009 127.0
HFD2_k127_3066118_4 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 5.421e-236 737.0
HFD2_k127_3066118_5 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 9.317e-228 719.0
HFD2_k127_3066118_6 Belongs to the aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 559.0
HFD2_k127_3066118_7 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000055 533.0
HFD2_k127_3066118_8 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 494.0
HFD2_k127_3066118_9 PFAM Acetyl-CoA hydrolase transferase K01067 - 3.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 475.0
HFD2_k127_3121431_0 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006164 370.0
HFD2_k127_3121431_1 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000002977 238.0
HFD2_k127_3121431_2 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.000000000000000000000000000000000000000000000000000006459 190.0
HFD2_k127_3306265_0 two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 6.646e-221 693.0
HFD2_k127_3306265_1 flavoprotein involved in K transport - GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 2.392e-215 678.0
HFD2_k127_3306265_2 Histidine kinase K02668,K07709 - 2.7.13.3 7.74e-215 683.0
HFD2_k127_3306265_3 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.000000000000000000000000000000000000000000000000000000000000003073 221.0
HFD2_k127_3306265_4 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 0.000000000000000000000000000000000000000000000000000000006006 199.0
HFD2_k127_3306265_5 cytochrome c K15876 - - 0.00000000000000000000000000000000000000000000000000009811 194.0
HFD2_k127_3322016_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 2.146e-215 692.0
HFD2_k127_3322016_1 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 7.266e-198 627.0
HFD2_k127_3322016_10 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030312,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0071944,GO:0140096,GO:1901564 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000001714 239.0
HFD2_k127_3322016_11 protein trimerization K15368 - - 0.00000000000000000000000000000000000000000000000000002104 197.0
HFD2_k127_3322016_12 MerR, DNA binding K19591 - - 0.0000000000000000000000000000000000000000000000004236 180.0
HFD2_k127_3322016_13 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000008929 167.0
HFD2_k127_3322016_15 peptidase activity, acting on L-amino acid peptides K20276 - - 0.00003184 54.0
HFD2_k127_3322016_2 Histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006179 620.0
HFD2_k127_3322016_3 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008325 444.0
HFD2_k127_3322016_4 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 431.0
HFD2_k127_3322016_5 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 315.0
HFD2_k127_3322016_6 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 307.0
HFD2_k127_3322016_7 PQQ enzyme repeat K17713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 336.0
HFD2_k127_3322016_8 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001267 271.0
HFD2_k127_3322016_9 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007987 279.0
HFD2_k127_3454561_0 homoserine dehydrogenase K00003 - 1.1.1.3 1.466e-202 648.0
HFD2_k127_3454561_1 HB1, ASXL, restriction endonuclease HTH domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 535.0
HFD2_k127_3454561_2 PFAM Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000427 316.0
HFD2_k127_3454561_4 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000000000000000000000009918 196.0
HFD2_k127_3454561_5 negative regulation of translational initiation - - - 0.00000000000000000000000000000000000000000000000002432 186.0
HFD2_k127_3454561_6 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000003471 181.0
HFD2_k127_3454561_7 deoxyhypusine monooxygenase activity - - - 0.00000000000000000000000000000000000000000004707 172.0
HFD2_k127_3454561_8 - - - - 0.0000001336 57.0
HFD2_k127_3454561_9 PQQ-like domain - - - 0.0007475 51.0
HFD2_k127_3515884_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 8.787e-318 980.0
HFD2_k127_3515884_1 Pyridoxal-phosphate dependent enzyme K01697 - 4.2.1.22 1.07e-250 781.0
HFD2_k127_3515884_10 Nucleoside H+ symporter K05820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 417.0
HFD2_k127_3515884_11 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 379.0
HFD2_k127_3515884_12 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 372.0
HFD2_k127_3515884_13 Diacylglycerol kinase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000322 364.0
HFD2_k127_3515884_14 Deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 329.0
HFD2_k127_3515884_15 Transport and Golgi organisation 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004408 270.0
HFD2_k127_3515884_16 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000000000000005832 204.0
HFD2_k127_3515884_18 Protein of unknown function (DUF971) K03593 - - 0.00000000000000000000000000002527 133.0
HFD2_k127_3515884_2 Cys Met metabolism K01739,K01758,K01761 - 2.5.1.48,4.4.1.1,4.4.1.11 7.835e-203 636.0
HFD2_k127_3515884_3 Ribosomal protein S1-like RNA-binding domain K02945 - - 1.551e-195 629.0
HFD2_k127_3515884_4 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 521.0
HFD2_k127_3515884_5 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 525.0
HFD2_k127_3515884_6 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 505.0
HFD2_k127_3515884_7 Domain of unknown function (DUF4388) K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007378 460.0
HFD2_k127_3515884_8 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 442.0
HFD2_k127_3515884_9 Nucleotidyl transferase K00966,K16881 - 2.7.7.13,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007538 419.0
HFD2_k127_3515909_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0 1266.0
HFD2_k127_3515909_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.012e-233 768.0
HFD2_k127_3515909_10 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000001267 248.0
HFD2_k127_3515909_11 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000002959 247.0
HFD2_k127_3515909_12 Oxygen tolerance - - - 0.00000000000000000000000000000000000000000000000000000006177 220.0
HFD2_k127_3515909_13 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000008108 164.0
HFD2_k127_3515909_14 - - - - 0.000000000000000008919 98.0
HFD2_k127_3515909_15 Tetratricopeptide repeat K07114 - - 0.000000001391 71.0
HFD2_k127_3515909_16 Cytochrome c K00406,K08906 - - 0.000002731 53.0
HFD2_k127_3515909_17 Tetratricopeptide repeat - - - 0.000006393 59.0
HFD2_k127_3515909_2 glutamate--cysteine ligase K01919 - 6.3.2.2 3.876e-207 656.0
HFD2_k127_3515909_3 Transglycosylase SLT domain K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 561.0
HFD2_k127_3515909_4 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 492.0
HFD2_k127_3515909_5 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 439.0
HFD2_k127_3515909_6 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 437.0
HFD2_k127_3515909_7 ZIP Zinc transporter K16267 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003547 325.0
HFD2_k127_3515909_8 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006265 297.0
HFD2_k127_3515909_9 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006205 265.0
HFD2_k127_3516006_0 AMP-binding enzyme - - - 4.382e-214 687.0
HFD2_k127_3516006_1 ABC-type branched-chain amino acid transport K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 501.0
HFD2_k127_3516006_10 Isoprenylcysteine carboxyl methyltransferase (ICMT) family K16168 - - 0.000000000000000000000000000000000000000000000001398 198.0
HFD2_k127_3516006_11 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000009912 79.0
HFD2_k127_3516006_2 AMP-binding enzyme C-terminal domain K12429,K18662 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0051087 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003863 497.0
HFD2_k127_3516006_3 Chalcone and stilbene synthases, C-terminal domain K16167,K19580 - 2.3.1.233 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 481.0
HFD2_k127_3516006_4 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000841 382.0
HFD2_k127_3516006_5 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 366.0
HFD2_k127_3516006_6 geranylgeranyl reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000056 310.0
HFD2_k127_3516006_7 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005758 287.0
HFD2_k127_3516006_8 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001767 287.0
HFD2_k127_3516006_9 Conserved protein containing a Zn-ribbon-like motif possibly RNA-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003045 253.0
HFD2_k127_3529919_0 DEAD/H associated K03724 - - 0.0 1765.0
HFD2_k127_3529919_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 9.503e-314 971.0
HFD2_k127_3529919_10 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 2.886e-197 619.0
HFD2_k127_3529919_11 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 1.941e-195 621.0
HFD2_k127_3529919_12 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000055 637.0
HFD2_k127_3529919_13 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006321 578.0
HFD2_k127_3529919_14 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009335 570.0
HFD2_k127_3529919_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005394 559.0
HFD2_k127_3529919_16 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007119 548.0
HFD2_k127_3529919_17 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008144,GO:0016874,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000317 567.0
HFD2_k127_3529919_18 Belongs to the methyltransferase superfamily K07444,K12297 - 2.1.1.173,2.1.1.264 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009636 512.0
HFD2_k127_3529919_19 Zinc-binding dehydrogenase K00060 - 1.1.1.103 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005401 519.0
HFD2_k127_3529919_2 AcrB/AcrD/AcrF family - - - 1.048e-305 986.0
HFD2_k127_3529919_20 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004369 497.0
HFD2_k127_3529919_21 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005142 494.0
HFD2_k127_3529919_22 Proton-dependent permease that transports di- and tripeptides K03305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 505.0
HFD2_k127_3529919_23 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 496.0
HFD2_k127_3529919_24 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004713 485.0
HFD2_k127_3529919_25 Histidine kinase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 440.0
HFD2_k127_3529919_26 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 406.0
HFD2_k127_3529919_28 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 402.0
HFD2_k127_3529919_29 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004048 387.0
HFD2_k127_3529919_3 Selenocysteine-specific translation elongation factor K03833 - - 5.038e-285 896.0
HFD2_k127_3529919_30 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 368.0
HFD2_k127_3529919_31 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 350.0
HFD2_k127_3529919_32 Two component transcriptional regulator, winged helix family K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007492 341.0
HFD2_k127_3529919_33 Transcriptional regulatory protein, C terminal K07658 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 348.0
HFD2_k127_3529919_34 TRAP transporter T-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 316.0
HFD2_k127_3529919_35 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA K07444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 308.0
HFD2_k127_3529919_36 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 307.0
HFD2_k127_3529919_37 Protein of unknown function (DUF533) K11962 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 302.0
HFD2_k127_3529919_38 thiolester hydrolase activity K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003281 282.0
HFD2_k127_3529919_39 hydrolase activity, acting on ester bonds K07051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000489 300.0
HFD2_k127_3529919_4 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 1.041e-277 869.0
HFD2_k127_3529919_40 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005384 282.0
HFD2_k127_3529919_41 O-methyltransferase K00588 - 2.1.1.104 0.00000000000000000000000000000000000000000000000000000000000000000000000000006653 263.0
HFD2_k127_3529919_42 PAP2 superfamily C-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000535 277.0
HFD2_k127_3529919_43 Methyl-transferase K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000398 275.0
HFD2_k127_3529919_44 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001199 244.0
HFD2_k127_3529919_45 Phosphoribosyl transferase domain K07101 - - 0.0000000000000000000000000000000000000000000000000000000000000002124 223.0
HFD2_k127_3529919_46 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000000000000000000000000000000000001943 245.0
HFD2_k127_3529919_47 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.00000000000000000000000000000000000000000000000000000000000002873 234.0
HFD2_k127_3529919_48 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000003082 224.0
HFD2_k127_3529919_49 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000003264 190.0
HFD2_k127_3529919_5 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 1.063e-277 870.0
HFD2_k127_3529919_50 Protein of unknown function (DUF423) - - - 0.000000000000000000000000000000000000000000000004731 175.0
HFD2_k127_3529919_51 Protein of unknown function (DUF2845) - - - 0.0000000000000000000000000000000000000000000005168 177.0
HFD2_k127_3529919_52 - - - - 0.000000000000000000000000000000000000002591 158.0
HFD2_k127_3529919_53 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000000000004438 142.0
HFD2_k127_3529919_54 Histidine kinase - - - 0.000000000000000000000000000000000004499 156.0
HFD2_k127_3529919_55 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000002331 149.0
HFD2_k127_3529919_56 RND efflux system, outer membrane lipoprotein, NodT family - - - 0.0000005662 62.0
HFD2_k127_3529919_6 ABC transporter, ATP-binding protein - - - 3.392e-257 814.0
HFD2_k127_3529919_7 Tripartite ATP-independent periplasmic transporter, DctM component - - - 8.97e-251 792.0
HFD2_k127_3529919_8 response regulator K07713 - - 4.912e-213 670.0
HFD2_k127_3529919_9 amino acid peptide transporter K03305 - - 8.699e-206 648.0
HFD2_k127_3531037_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 3.694e-234 732.0
HFD2_k127_3531037_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007634 360.0
HFD2_k127_3531037_2 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000009993 226.0
HFD2_k127_3531037_3 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000000000000000000000000000000000000000000004399 192.0
HFD2_k127_3554020_0 Domain of unknown function (DUF5117) - - - 1.93e-210 680.0
HFD2_k127_3554759_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 2.284e-197 626.0
HFD2_k127_3554759_1 Protein of unknown function (DUF1257) - - - 0.00004127 47.0
HFD2_k127_3554759_2 Protein of unknown function (DUF2997) - - - 0.0001398 49.0
HFD2_k127_3595641_0 AlkA N-terminal domain K13529 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 390.0
HFD2_k127_3595641_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009792 283.0
HFD2_k127_3595641_2 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000001209 156.0
HFD2_k127_3595641_3 serine threonine protein kinase - - - 0.00000005049 54.0
HFD2_k127_3626084_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1182.0
HFD2_k127_3626084_1 General secretory system II, protein E domain protein K02454 - - 0.0 1017.0
HFD2_k127_3626084_10 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 6.735e-211 662.0
HFD2_k127_3626084_11 ATPase family associated with various cellular activities (AAA) - - - 1.585e-210 694.0
HFD2_k127_3626084_12 ubiquinol oxidase subunit I K00425 - 1.10.3.14 4.092e-203 642.0
HFD2_k127_3626084_13 UDP binding domain K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003404 578.0
HFD2_k127_3626084_14 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 567.0
HFD2_k127_3626084_15 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004648 526.0
HFD2_k127_3626084_16 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007911 519.0
HFD2_k127_3626084_17 lipopolysaccharide transport K04744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 524.0
HFD2_k127_3626084_18 PFAM NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 485.0
HFD2_k127_3626084_19 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004255 491.0
HFD2_k127_3626084_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 7.796e-318 986.0
HFD2_k127_3626084_20 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000429 462.0
HFD2_k127_3626084_21 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004539 489.0
HFD2_k127_3626084_22 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 457.0
HFD2_k127_3626084_23 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006043 436.0
HFD2_k127_3626084_24 DnaJ C terminal domain K03686,K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005477 409.0
HFD2_k127_3626084_25 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 418.0
HFD2_k127_3626084_26 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004023 417.0
HFD2_k127_3626084_27 oxidase, subunit K00426 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009326 434.0
HFD2_k127_3626084_28 -O-antigen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 417.0
HFD2_k127_3626084_29 Nucleotidyl transferase K00978 - 2.7.7.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 383.0
HFD2_k127_3626084_3 Asparagine synthase K01953 - 6.3.5.4 3.359e-313 975.0
HFD2_k127_3626084_30 Glycosyl transferases group 1 K20444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 382.0
HFD2_k127_3626084_31 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 380.0
HFD2_k127_3626084_32 Inositol monophosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 356.0
HFD2_k127_3626084_33 extracellular polysaccharide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003803 376.0
HFD2_k127_3626084_34 ATP-grasp - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 355.0
HFD2_k127_3626084_35 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004395 335.0
HFD2_k127_3626084_36 Penicillin amidase K01434 - 3.5.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003068 344.0
HFD2_k127_3626084_37 Transcriptional regulator, CarD family K07736 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 301.0
HFD2_k127_3626084_38 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 295.0
HFD2_k127_3626084_39 Bacterial regulatory proteins, tetR family K13770 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003212 275.0
HFD2_k127_3626084_4 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 1.533e-287 909.0
HFD2_k127_3626084_40 Protein involved in cellulose biosynthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006883 281.0
HFD2_k127_3626084_41 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001806 283.0
HFD2_k127_3626084_42 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005793 268.0
HFD2_k127_3626084_43 Belongs to the glycosyltransferase 26 family K05946 - 2.4.1.187 0.000000000000000000000000000000000000000000000000000000000000000000000000002194 261.0
HFD2_k127_3626084_44 PFAM GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001903 258.0
HFD2_k127_3626084_45 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000001678 257.0
HFD2_k127_3626084_46 ADP-glyceromanno-heptose 6-epimerase activity K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000153 205.0
HFD2_k127_3626084_47 polysaccharide export K01991 - - 0.00000000000000000000000000000000000000000000000000001732 203.0
HFD2_k127_3626084_48 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.000000000000000000000000000000000000000000000000003351 185.0
HFD2_k127_3626084_49 - - - - 0.00000000000000000000000000000000000000000000000005859 186.0
HFD2_k127_3626084_5 D-isomer specific 2-hydroxyacid dehydrogenase K00058,K16843 - 1.1.1.310,1.1.1.399,1.1.1.95 3.457e-238 747.0
HFD2_k127_3626084_51 lytic transglycosylase activity - - - 0.000000000000000000000000000000000000000000006648 171.0
HFD2_k127_3626084_53 Putative collagen-binding domain of a collagenase - - - 0.00000000000000000000000000000000000000000002708 184.0
HFD2_k127_3626084_54 translation initiation factor activity - - - 0.0000000000000000000000000000000000000002691 158.0
HFD2_k127_3626084_55 Cellulase N-terminal ig-like domain K01179 - 3.2.1.4 0.0000000000000000000000000000000000000004113 173.0
HFD2_k127_3626084_56 polysaccharide biosynthetic process - - - 0.0000000000000000000000000000000000005223 159.0
HFD2_k127_3626084_57 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000172 149.0
HFD2_k127_3626084_58 Lipoprotein K05811 - - 0.000000000000000000000000000000003473 147.0
HFD2_k127_3626084_6 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 9.672e-234 752.0
HFD2_k127_3626084_61 deoxyhypusine monooxygenase activity - - - 0.000000000000000000000000002113 122.0
HFD2_k127_3626084_62 TPR repeat - - - 0.0000000000000000000000007902 115.0
HFD2_k127_3626084_63 Dolichyl-phosphate-mannose-protein mannosyltransferase K14340 - - 0.000000000000000000000006205 117.0
HFD2_k127_3626084_64 histone H2A K63-linked ubiquitination K03466 - - 0.000000000000000002387 93.0
HFD2_k127_3626084_65 - - - - 0.00000000002305 78.0
HFD2_k127_3626084_67 epimerase dehydratase K01784,K19997 - 5.1.3.2,5.1.3.26 0.00000001742 66.0
HFD2_k127_3626084_68 Male sterility protein - - - 0.0000001353 63.0
HFD2_k127_3626084_69 - - - - 0.000001436 59.0
HFD2_k127_3626084_7 peptidase S9B dipeptidylpeptidase IV domain protein K01278 - 3.4.14.5 3.005e-224 717.0
HFD2_k127_3626084_70 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00002432 57.0
HFD2_k127_3626084_71 polysaccharide biosynthetic process - - - 0.0003496 53.0
HFD2_k127_3626084_8 DNA internalization-related competence protein ComEC Rec2 K02238 - - 1.185e-214 691.0
HFD2_k127_3626084_9 Homoserine dehydrogenase, NAD binding domain - - - 4.964e-211 665.0
HFD2_k127_3640151_0 Transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003052 250.0
HFD2_k127_3640151_1 PFAM amino acid-binding ACT domain protein - - - 0.000000000000000000000000000000000000001292 149.0
HFD2_k127_3673728_0 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.0 1001.0
HFD2_k127_3673728_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 2.285e-206 648.0
HFD2_k127_3673728_10 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002846 288.0
HFD2_k127_3673728_11 glycosylase i K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000002771 238.0
HFD2_k127_3673728_12 Belongs to the GbsR family - - - 0.000000000000000000000000000000000000000000000000000000000006279 231.0
HFD2_k127_3673728_13 Transcription factor zinc-finger K09981 - - 0.000000000000000000000000000000000000000000000000001857 190.0
HFD2_k127_3673728_14 PFAM amidohydrolase K20810 - 3.5.4.40 0.000000000000000000000000000000000000001672 171.0
HFD2_k127_3673728_15 Transposase DDE domain K07492 - - 0.00000000000000000000000000000000003468 141.0
HFD2_k127_3673728_16 energy transducer activity K03832 - - 0.0005324 51.0
HFD2_k127_3673728_2 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 7.832e-199 623.0
HFD2_k127_3673728_3 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K11779,K11784,K18285 - 1.21.98.1,2.5.1.120,2.5.1.77 1.287e-197 621.0
HFD2_k127_3673728_4 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 599.0
HFD2_k127_3673728_5 UbiA prenyltransferase family K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 410.0
HFD2_k127_3673728_6 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002843 359.0
HFD2_k127_3673728_7 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 375.0
HFD2_k127_3673728_8 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007546 350.0
HFD2_k127_3673728_9 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 306.0
HFD2_k127_3683220_0 Insulinase (Peptidase family M16) K07263 - - 0.0 1159.0
HFD2_k127_3683220_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 3.084e-278 869.0
HFD2_k127_3683220_10 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K12251 - 3.5.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 421.0
HFD2_k127_3683220_11 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 372.0
HFD2_k127_3683220_12 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 355.0
HFD2_k127_3683220_13 PFAM ABC transporter related K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 370.0
HFD2_k127_3683220_14 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 365.0
HFD2_k127_3683220_15 FtsZ-dependent cytokinesis K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000002147 229.0
HFD2_k127_3683220_16 Periplasmic binding protein K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000821 227.0
HFD2_k127_3683220_18 gamma-glutamylcyclotransferase activity - - - 0.0000000000000000000000000000000000000000000000000000002488 199.0
HFD2_k127_3683220_19 PAS domain - - - 0.00000000000000000000000000007044 123.0
HFD2_k127_3683220_2 Domain of unknown function (DUF3413) K07014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 574.0
HFD2_k127_3683220_20 - - - - 0.0000000000000000000000003896 110.0
HFD2_k127_3683220_3 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007003 539.0
HFD2_k127_3683220_4 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 541.0
HFD2_k127_3683220_5 PFAM FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 492.0
HFD2_k127_3683220_6 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005297 498.0
HFD2_k127_3683220_7 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006918 459.0
HFD2_k127_3683220_8 Peptidase dimerisation domain K01295 - 3.4.17.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 441.0
HFD2_k127_3683220_9 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005571 412.0
HFD2_k127_3690164_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1396.0
HFD2_k127_3690164_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1270.0
HFD2_k127_3690164_10 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 617.0
HFD2_k127_3690164_11 Stage II sporulation protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 623.0
HFD2_k127_3690164_12 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003512 566.0
HFD2_k127_3690164_13 PhoH-like protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005969 545.0
HFD2_k127_3690164_14 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 535.0
HFD2_k127_3690164_15 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002285 503.0
HFD2_k127_3690164_16 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 480.0
HFD2_k127_3690164_17 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008433 477.0
HFD2_k127_3690164_18 Male sterility protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 449.0
HFD2_k127_3690164_19 AAA domain (Cdc48 subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004659 445.0
HFD2_k127_3690164_2 fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1043.0
HFD2_k127_3690164_20 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005831 461.0
HFD2_k127_3690164_21 phospholipase C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008924 427.0
HFD2_k127_3690164_22 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000492 418.0
HFD2_k127_3690164_23 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 438.0
HFD2_k127_3690164_24 LysM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002967 404.0
HFD2_k127_3690164_25 MazG nucleotide pyrophosphohydrolase domain K02499,K04765 - 3.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004818 371.0
HFD2_k127_3690164_26 Fumarate reductase, iron-sulfur protein K00240,K00245 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 396.0
HFD2_k127_3690164_27 PilZ domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006154 376.0
HFD2_k127_3690164_28 nuclear chromosome segregation K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 353.0
HFD2_k127_3690164_29 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000492 330.0
HFD2_k127_3690164_3 copper-translocating P-type ATPase K17686 - 3.6.3.54 1.89e-321 1005.0
HFD2_k127_3690164_30 Aminotransferase K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 319.0
HFD2_k127_3690164_31 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008697 304.0
HFD2_k127_3690164_32 DNA recombination-mediator protein A K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 304.0
HFD2_k127_3690164_33 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 310.0
HFD2_k127_3690164_34 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008369 280.0
HFD2_k127_3690164_35 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001685 285.0
HFD2_k127_3690164_36 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005772 265.0
HFD2_k127_3690164_37 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000228 261.0
HFD2_k127_3690164_38 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus K04760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001633 256.0
HFD2_k127_3690164_39 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000006244 244.0
HFD2_k127_3690164_4 heat shock protein 70 K04043 - - 7.191e-299 937.0
HFD2_k127_3690164_40 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000000000000000000005286 222.0
HFD2_k127_3690164_41 membrane - - - 0.00000000000000000000000000000000000000000000000000000009096 214.0
HFD2_k127_3690164_42 NADPH-dependent FMN reductase K19784 - - 0.000000000000000000000000000000000000000000000000000009487 193.0
HFD2_k127_3690164_43 fumarate reductase) cytochrome b subunit K00241 - - 0.00000000000000000000000000000000000000000000000000004871 199.0
HFD2_k127_3690164_44 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine K04068 - 1.97.1.4 0.000000000000000000000000000000000000000000000003772 192.0
HFD2_k127_3690164_45 N-terminal half of MaoC dehydratase - - - 0.00000000000000000000000000000000000000000000002189 174.0
HFD2_k127_3690164_47 RDD family - - - 0.000000000000000000000000000000000000000000006731 175.0
HFD2_k127_3690164_48 MaoC like domain - - - 0.00000000000000000000000000000000000000000001112 181.0
HFD2_k127_3690164_49 amine dehydrogenase activity K21449 - - 0.0000000000000000000000000000000000000000000345 170.0
HFD2_k127_3690164_5 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 7.759e-217 687.0
HFD2_k127_3690164_50 IMP dehydrogenase activity - - - 0.000000000000000000000000000000000000001379 160.0
HFD2_k127_3690164_52 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000000000000295 161.0
HFD2_k127_3690164_53 - - - - 0.0000000000000000000000000000000124 130.0
HFD2_k127_3690164_56 Protein of unknown function (DUF2089) - - - 0.000000000000000000001659 97.0
HFD2_k127_3690164_58 CotH kinase protein - - - 0.000000005493 68.0
HFD2_k127_3690164_59 - - - - 0.000001013 59.0
HFD2_k127_3690164_6 7TM receptor with intracellular HD hydrolase K07037 - - 5.369e-215 693.0
HFD2_k127_3690164_60 YoaP-like - - - 0.000008092 57.0
HFD2_k127_3690164_7 twitching motility protein K02669 - - 3.362e-200 631.0
HFD2_k127_3690164_8 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 3.064e-195 632.0
HFD2_k127_3690164_9 acetylornithine aminotransferase K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 610.0
HFD2_k127_3717024_0 helicase - - - 0.0 1115.0
HFD2_k127_3717024_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0 1072.0
HFD2_k127_3717024_10 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00112 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003392 449.0
HFD2_k127_3717024_11 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 386.0
HFD2_k127_3717024_13 associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 358.0
HFD2_k127_3717024_14 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 314.0
HFD2_k127_3717024_15 tRNA methyltransferase complex GCD14 subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003251 274.0
HFD2_k127_3717024_16 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000006496 253.0
HFD2_k127_3717024_17 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000000000000000000006592 224.0
HFD2_k127_3717024_18 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000009302 210.0
HFD2_k127_3717024_19 exonuclease activity K16899 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000001219 199.0
HFD2_k127_3717024_2 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 1.481e-275 856.0
HFD2_k127_3717024_20 Tripartite tricarboxylate transporter TctB family - - - 0.00000000000000000000000000000000000000000000000000431 187.0
HFD2_k127_3717024_21 Crp-like helix-turn-helix domain K10914 - - 0.00000000000000000000000000000000000000000000000007404 186.0
HFD2_k127_3717024_22 4Fe-4S dicluster domain K00125,K03646 - 1.17.1.9 0.00000000000000000000000000000000000002529 166.0
HFD2_k127_3717024_23 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.000000000000000000000000000000001284 136.0
HFD2_k127_3717024_24 PFAM DoxX family protein - - - 0.00000000000000000000000000001565 129.0
HFD2_k127_3717024_25 thiamine diphosphate biosynthetic process K03154 - - 0.0000000000000000000000007016 105.0
HFD2_k127_3717024_26 Domain of unknown function (DUF4350) - - - 0.000000000000000000304 103.0
HFD2_k127_3717024_27 - - - - 0.000001114 61.0
HFD2_k127_3717024_3 single-stranded-DNA-specific exonuclease RecJ K07462 - - 3.672e-256 805.0
HFD2_k127_3717024_4 Tripartite tricarboxylate transporter TctA family K07793 - - 2.736e-247 780.0
HFD2_k127_3717024_5 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 1.551e-208 655.0
HFD2_k127_3717024_6 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004927 574.0
HFD2_k127_3717024_7 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 567.0
HFD2_k127_3717024_8 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008021 524.0
HFD2_k127_3717024_9 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000423 442.0
HFD2_k127_373181_0 SMART Elongator protein 3 MiaB NifB - - - 0.0 1352.0
HFD2_k127_373181_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01539 - 3.6.3.9 0.0 1196.0
HFD2_k127_373181_10 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013,K15509 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23,1.1.1.308 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 370.0
HFD2_k127_373181_11 Virulence factor BrkB K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006079 363.0
HFD2_k127_373181_12 zinc metalloprotease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005322 354.0
HFD2_k127_373181_13 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006299 307.0
HFD2_k127_373181_14 Imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 306.0
HFD2_k127_373181_15 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401,K03229 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007951 278.0
HFD2_k127_373181_16 type iii secretion K03226 - - 0.000000000000000000000000000000000000000000000000000000000000000000001272 250.0
HFD2_k127_373181_17 BON domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002799 257.0
HFD2_k127_373181_18 PFAM CBS domain containing protein K04767 - - 0.0000000000000000000000000000000000000000000000000000000000002341 228.0
HFD2_k127_373181_19 Secretory protein of YscJ/FliF family K03222 - - 0.00000000000000000000000000000000000000000000000000000000001054 216.0
HFD2_k127_373181_2 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 2.536e-317 984.0
HFD2_k127_373181_20 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02416,K02417,K03225 GO:0005575,GO:0005623,GO:0005886,GO:0006935,GO:0008150,GO:0009288,GO:0009425,GO:0009605,GO:0016020,GO:0040011,GO:0042221,GO:0042330,GO:0042995,GO:0043226,GO:0043228,GO:0044403,GO:0044419,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0052116,GO:0052126,GO:0052127,GO:0052143,GO:0052192,GO:0052195,GO:0052216,GO:0052243,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000001796 220.0
HFD2_k127_373181_21 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000005329 209.0
HFD2_k127_373181_22 Belongs to the bacterial histone-like protein family K05788 - - 0.00000000000000000000000000000000000000000000000000003255 189.0
HFD2_k127_373181_24 bacterial-type flagellum assembly K02421,K03228,K13820 - - 0.000000000000000000000000000000000000000002948 168.0
HFD2_k127_373181_25 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000000000000000000000000000009647 165.0
HFD2_k127_373181_28 Binds the 23S rRNA K02909 - - 0.00000000000000000005997 92.0
HFD2_k127_373181_29 acylphosphatase activity K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.0000000000000000003214 103.0
HFD2_k127_373181_3 Heat shock 70 kDa protein K04043 - - 1.119e-283 885.0
HFD2_k127_373181_30 bacterial-type flagellum assembly K02420,K03227 - - 0.000000000000000001296 96.0
HFD2_k127_373181_31 translation initiation factor activity K03699 - - 0.0000000000000000058 89.0
HFD2_k127_373181_32 Prokaryotic N-terminal methylation motif K02456,K02650 - - 0.0000001646 64.0
HFD2_k127_373181_4 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.872e-252 779.0
HFD2_k127_373181_5 Ribonuclease E/G family K08301 - - 3.54e-209 674.0
HFD2_k127_373181_6 DUF1704 - - - 1.435e-196 634.0
HFD2_k127_373181_7 Type III secretion protein K03230 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 624.0
HFD2_k127_373181_8 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008518 482.0
HFD2_k127_373181_9 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005113 443.0
HFD2_k127_3737052_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620,K00930 - 2.3.1.1,2.3.1.35,2.7.2.8 0.0 1065.0
HFD2_k127_3737052_1 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 8.513e-257 816.0
HFD2_k127_3737052_2 Cytochrome C biogenesis protein transmembrane region K04084 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 553.0
HFD2_k127_3737052_3 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145,K05829 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 474.0
HFD2_k127_3737052_4 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 GO:0001522,GO:0003674,GO:0003824,GO:0004123,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009000,GO:0009058,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016226,GO:0016740,GO:0016769,GO:0016782,GO:0016783,GO:0016829,GO:0016846,GO:0018130,GO:0018131,GO:0019842,GO:0022607,GO:0030170,GO:0031071,GO:0031119,GO:0031163,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097163,GO:0140104,GO:1901360,GO:1901363 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 484.0
HFD2_k127_3737052_5 Regulates arginine biosynthesis genes K03402 - - 0.000000000000000000000000000000000000002832 170.0
HFD2_k127_3753333_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 3.238e-254 798.0
HFD2_k127_3753333_1 carbon dioxide binding K04653,K04654 - - 0.0000000002734 74.0
HFD2_k127_3821582_0 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000007572 224.0
HFD2_k127_3821582_1 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000267 121.0
HFD2_k127_38421_0 Asparagine synthase K01953 - 6.3.5.4 8.768e-319 985.0
HFD2_k127_38421_1 Glycosyl hydrolase family 9 K01179 - 3.2.1.4 1.624e-212 721.0
HFD2_k127_38421_10 PFAM NAD-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008441 483.0
HFD2_k127_38421_11 Glycosyl transferases group 1 K20444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006889 508.0
HFD2_k127_38421_12 NmrA-like family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 472.0
HFD2_k127_38421_13 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009186 450.0
HFD2_k127_38421_14 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006868 429.0
HFD2_k127_38421_15 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 418.0
HFD2_k127_38421_16 -O-antigen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006526 406.0
HFD2_k127_38421_17 extracellular polysaccharide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008999 394.0
HFD2_k127_38421_18 Inositol monophosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 362.0
HFD2_k127_38421_19 Nucleotidyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009985 375.0
HFD2_k127_38421_2 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 3.127e-194 618.0
HFD2_k127_38421_20 ATP-grasp - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 358.0
HFD2_k127_38421_21 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006182 256.0
HFD2_k127_38421_22 Protein involved in cellulose biosynthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001627 265.0
HFD2_k127_38421_23 Putative collagen-binding domain of a collagenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008517 281.0
HFD2_k127_38421_24 Belongs to the glycosyltransferase 26 family K05946 - 2.4.1.187 0.000000000000000000000000000000000000000000000000000000000000000000000008023 251.0
HFD2_k127_38421_25 Polysaccharide pyruvyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000008165 239.0
HFD2_k127_38421_26 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000000000000000008639 235.0
HFD2_k127_38421_27 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000003598 244.0
HFD2_k127_38421_28 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K00067,K01790 - 1.1.1.133,5.1.3.13 0.000000000000000000000000000000000000000000000000000000000004646 219.0
HFD2_k127_38421_29 polysaccharide export K01991 - - 0.00000000000000000000000000000000000000000000006466 177.0
HFD2_k127_38421_3 UDP binding domain K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 594.0
HFD2_k127_38421_30 polysaccharide biosynthetic process - - - 0.0000000000000000000000000000000000000000000007002 192.0
HFD2_k127_38421_32 - - - - 0.00003094 54.0
HFD2_k127_38421_4 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 569.0
HFD2_k127_38421_5 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005422 563.0
HFD2_k127_38421_6 PFAM aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 551.0
HFD2_k127_38421_7 winged helix-turn-helix - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 540.0
HFD2_k127_38421_8 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 511.0
HFD2_k127_38421_9 Acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006583 511.0
HFD2_k127_390601_0 Caspase domain - - - 0.000000000000000000000000000000000000000000000001805 193.0
HFD2_k127_390601_1 Involved in the TonB-independent uptake of proteins K03641 - - 0.00000000000000000000000000005493 136.0
HFD2_k127_390601_2 AntiSigma factor - - - 0.00000000000002126 83.0
HFD2_k127_390601_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000008561 79.0
HFD2_k127_3924359_0 Protein of unknown function, DUF255 K06888 - - 1.118e-281 883.0
HFD2_k127_3924359_1 AMP-binding enzyme K01897 - 6.2.1.3 4.27e-271 846.0
HFD2_k127_3924359_10 Chromosome Partitioning K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 351.0
HFD2_k127_3924359_11 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 292.0
HFD2_k127_3924359_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006175 262.0
HFD2_k127_3924359_13 PHB/PHA accumulation regulator DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000002381 223.0
HFD2_k127_3924359_14 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000007072 246.0
HFD2_k127_3924359_15 cytochrome c K15876 - - 0.0000000000000000000000000000000000000000000000000000002488 199.0
HFD2_k127_3924359_16 PFAM Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000007151 177.0
HFD2_k127_3924359_17 - - - - 0.000000000000000000000000000000000000000000000006174 188.0
HFD2_k127_3924359_18 zinc-ribbon domain - - - 0.00000000000000000000000000000000602 143.0
HFD2_k127_3924359_19 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000003177 70.0
HFD2_k127_3924359_2 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 1.54e-255 795.0
HFD2_k127_3924359_3 Belongs to the RtcB family K14415 - 6.5.1.3 6.09e-243 765.0
HFD2_k127_3924359_4 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 7.02e-226 707.0
HFD2_k127_3924359_5 two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 9.891e-209 704.0
HFD2_k127_3924359_6 Histidine kinase K02668,K07709 - 2.7.13.3 2.765e-206 659.0
HFD2_k127_3924359_7 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007286 512.0
HFD2_k127_3924359_8 Anion-transporting ATPase K01551 - 3.6.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 413.0
HFD2_k127_3924359_9 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 359.0
HFD2_k127_4032349_0 Transposase IS200 like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006037 312.0
HFD2_k127_4032349_1 Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001751 270.0
HFD2_k127_4056761_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 1.404e-226 707.0
HFD2_k127_4056761_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 4.952e-222 696.0
HFD2_k127_4056761_10 Domain of unknown function (DUF4395) - - - 0.000000000001128 78.0
HFD2_k127_4056761_11 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000271 66.0
HFD2_k127_4056761_12 Thioredoxin - - - 0.0002281 52.0
HFD2_k127_4056761_2 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 543.0
HFD2_k127_4056761_3 Elongator protein 3, MiaB family, Radical SAM K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 458.0
HFD2_k127_4056761_4 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 358.0
HFD2_k127_4056761_5 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001493 265.0
HFD2_k127_4056761_6 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000002781 214.0
HFD2_k127_4056761_7 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000000000000000000131 208.0
HFD2_k127_4069722_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 3.886e-235 764.0
HFD2_k127_4069722_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 517.0
HFD2_k127_4069722_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007006 502.0
HFD2_k127_4069722_4 Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007032 329.0
HFD2_k127_4069722_5 racemase activity, acting on amino acids and derivatives K01779 - 5.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000531 295.0
HFD2_k127_4069722_6 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000681 198.0
HFD2_k127_4161686_0 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.000000000000000000000000000000000000000000000000000000000001443 216.0
HFD2_k127_4161686_2 FecR protein - - - 0.0000004215 55.0
HFD2_k127_4161718_0 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.0000000000000000000000000000000000000000000000000000000000001739 217.0
HFD2_k127_4161718_1 - - - - 0.00000000000000000000000000000000000000000000000000003437 209.0
HFD2_k127_4161718_2 - - - - 0.00000000000000000000000000000000000000000002861 168.0
HFD2_k127_4161718_3 - - - - 0.000000000000000000000000000000000001384 144.0
HFD2_k127_4161718_5 FecR protein - - - 0.0008447 52.0
HFD2_k127_4189525_0 MazG nucleotide pyrophosphohydrolase domain K02499,K04765 - 3.6.1.9 0.0000000000000000000000000000000003457 133.0
HFD2_k127_4189525_2 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000004737 64.0
HFD2_k127_426327_0 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 359.0
HFD2_k127_426327_1 ABC transporter K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008625 308.0
HFD2_k127_426327_2 cell septum assembly - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007044 266.0
HFD2_k127_426327_3 Domain of unknown function (DUF4337) - - - 0.0000000000000000000000000000000000000000000003311 184.0
HFD2_k127_426327_4 - - - - 0.0000000000000000000000000179 121.0
HFD2_k127_426327_5 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000000000000005442 121.0
HFD2_k127_4265235_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1133.0
HFD2_k127_4265235_1 GTP-binding protein K06207 - - 0.0 1052.0
HFD2_k127_4265235_10 two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 496.0
HFD2_k127_4265235_11 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 476.0
HFD2_k127_4265235_12 B-1 B cell differentiation K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005645 412.0
HFD2_k127_4265235_13 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 385.0
HFD2_k127_4265235_14 A G-specific K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 371.0
HFD2_k127_4265235_15 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004613 346.0
HFD2_k127_4265235_16 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007966 335.0
HFD2_k127_4265235_17 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 303.0
HFD2_k127_4265235_18 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 309.0
HFD2_k127_4265235_19 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001407 279.0
HFD2_k127_4265235_2 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0 1020.0
HFD2_k127_4265235_20 TIGRFAM Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000346 264.0
HFD2_k127_4265235_21 GTP cyclohydrolase I K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000003934 240.0
HFD2_k127_4265235_22 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000004283 232.0
HFD2_k127_4265235_23 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000000000000000000006271 230.0
HFD2_k127_4265235_24 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000006744 216.0
HFD2_k127_4265235_25 - - - - 0.00000000000000000000000000000000000000000000000000002876 211.0
HFD2_k127_4265235_26 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.000000000000000000000000000000000000000000000000001781 188.0
HFD2_k127_4265235_27 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000000000000007235 182.0
HFD2_k127_4265235_29 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.000000000000000000000000000000000000000000000008424 173.0
HFD2_k127_4265235_3 Pyruvate flavodoxin ferredoxin K00174 - 1.2.7.11,1.2.7.3 1.389e-312 994.0
HFD2_k127_4265235_30 GAF domain K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000009871 185.0
HFD2_k127_4265235_31 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000007425 164.0
HFD2_k127_4265235_32 - - - - 0.000000000000000000000000000000000000000002145 181.0
HFD2_k127_4265235_33 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000971 167.0
HFD2_k127_4265235_34 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000119 145.0
HFD2_k127_4265235_35 PhoQ Sensor - - - 0.0000000000000000000000000000000191 135.0
HFD2_k127_4265235_36 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000006474 116.0
HFD2_k127_4265235_37 Ribbon-helix-helix domain - - - 0.000000000000000000000000007154 110.0
HFD2_k127_4265235_38 Rieske [2Fe-2S] domain K00363 - 1.7.1.15 0.0000000000000000000000000711 111.0
HFD2_k127_4265235_39 FecR protein - - - 0.000000000000000000000000106 115.0
HFD2_k127_4265235_4 acetolactate synthase K01576,K01652 - 2.2.1.6,4.1.1.7 4.145e-298 924.0
HFD2_k127_4265235_5 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 1.996e-259 807.0
HFD2_k127_4265235_6 FAD linked oxidases, C-terminal domain K00102,K00104 - 1.1.2.4,1.1.3.15 8.821e-222 710.0
HFD2_k127_4265235_7 PFAM thiamine pyrophosphate protein domain protein TPP-binding K00175 - 1.2.7.11,1.2.7.3 5.707e-194 608.0
HFD2_k127_4265235_8 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 8.661e-194 610.0
HFD2_k127_4265235_9 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 598.0
HFD2_k127_4399700_0 Polysaccharide biosynthesis/export protein K01991 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 439.0
HFD2_k127_4399700_1 - - - - 0.0000000000000000004371 96.0
HFD2_k127_4399700_2 RES domain - - - 0.000001078 52.0
HFD2_k127_4419524_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0 1080.0
HFD2_k127_4419524_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 2.107e-260 813.0
HFD2_k127_4419524_10 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006129 357.0
HFD2_k127_4419524_11 PFAM permease YjgP YjgQ family protein K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004092 324.0
HFD2_k127_4419524_12 Sigma-70, region 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001549 256.0
HFD2_k127_4419524_13 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000000000000009617 228.0
HFD2_k127_4419524_14 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000008811 243.0
HFD2_k127_4419524_15 Belongs to the SUA5 family K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000002098 231.0
HFD2_k127_4419524_16 RDD family - - - 0.000000000000000000000000000000000000000000000000000000000001665 214.0
HFD2_k127_4419524_17 MerR HTH family regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000002687 211.0
HFD2_k127_4419524_18 cyclic nucleotide-binding - - - 0.0000000000000000000000000000000000000000000000000002958 201.0
HFD2_k127_4419524_2 Peptidase family S58 K01266 - 3.4.11.19 1.102e-194 629.0
HFD2_k127_4419524_20 peptidyl-tyrosine sulfation - - - 0.00000000000000000219 100.0
HFD2_k127_4419524_3 Belongs to the ALAD family K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 586.0
HFD2_k127_4419524_4 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 573.0
HFD2_k127_4419524_5 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 563.0
HFD2_k127_4419524_6 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005706 546.0
HFD2_k127_4419524_7 protein kinase activity K08884 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 494.0
HFD2_k127_4419524_8 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 451.0
HFD2_k127_4419524_9 PFAM permease YjgP YjgQ family protein K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009559 386.0
HFD2_k127_4420191_0 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007032 256.0
HFD2_k127_4420191_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004406 261.0
HFD2_k127_4420191_2 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000002666 172.0
HFD2_k127_4428335_0 Peptidase family M50 K11749 - - 1.266e-215 682.0
HFD2_k127_4428335_1 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 3.352e-194 612.0
HFD2_k127_4428335_2 Belongs to the peptidase M50B family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 558.0
HFD2_k127_4428335_3 Domain of unknown function (DUF1731) K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008099 377.0
HFD2_k127_4428335_4 Semialdehyde dehydrogenase, NAD binding domain K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 326.0
HFD2_k127_4428335_5 Glycoprotease family K01409,K14742 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 303.0
HFD2_k127_4428335_7 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.00000000000000000000000000000000000000000000000001518 181.0
HFD2_k127_4428335_8 Stage II sporulation D domain protein K06381 - - 0.000000000000000000000000000000000000006356 157.0
HFD2_k127_4438897_0 Curli production assembly/transport component CsgG - - - 0.000000000000000000000000002507 119.0
HFD2_k127_4438897_2 diguanylate cyclase K02488 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 2.7.7.65 0.00001516 49.0
HFD2_k127_4479169_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00262 - 1.4.1.4 1.155e-216 732.0
HFD2_k127_4479169_1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 1.104e-201 645.0
HFD2_k127_4479169_10 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 321.0
HFD2_k127_4479169_11 thiosulfate sulfurtransferase activity K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 312.0
HFD2_k127_4479169_12 PGAP1-like protein K01046 - 3.1.1.3 0.00000000000000000000000000000000000000000000000000000000000001647 225.0
HFD2_k127_4479169_13 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000002449 205.0
HFD2_k127_4479169_15 - - - - 0.000000000000000000000000000000000181 140.0
HFD2_k127_4479169_16 Cupin domain - - - 0.00000000000000000000000000005547 123.0
HFD2_k127_4479169_17 thiosulfate sulfurtransferase activity K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000002084 114.0
HFD2_k127_4479169_18 translation initiation factor activity K03699 - - 0.0000000000000000000344 93.0
HFD2_k127_4479169_19 - - - - 0.000000000000000002649 96.0
HFD2_k127_4479169_2 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 5.377e-196 616.0
HFD2_k127_4479169_21 - - - - 0.0000002808 61.0
HFD2_k127_4479169_3 Molybdopterin oxidoreductase K00370,K17050 - 1.7.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004268 486.0
HFD2_k127_4479169_4 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 462.0
HFD2_k127_4479169_5 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 456.0
HFD2_k127_4479169_6 PFAM amino acid permease-associated region K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 385.0
HFD2_k127_4479169_7 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006536 356.0
HFD2_k127_4479169_8 - K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 335.0
HFD2_k127_4479169_9 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003992 332.0
HFD2_k127_4491706_0 Mur ligase family, catalytic domain K02558 - 6.3.2.45 8.151e-232 725.0
HFD2_k127_4527215_0 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 551.0
HFD2_k127_4527215_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008756 391.0
HFD2_k127_4527215_10 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000115 189.0
HFD2_k127_4527215_11 Cys-tRNA(Pro) hydrolase activity K19055 - - 0.0000000000000000000000000000000000000000000002407 177.0
HFD2_k127_4527215_12 Lrp/AsnC ligand binding domain - - - 0.000000000000000000000000000000006662 130.0
HFD2_k127_4527215_13 transposase activity K07483,K07497 - - 0.0000000000000000000001785 109.0
HFD2_k127_4527215_14 Peptidogalycan biosysnthesis/recognition K09919 - - 0.0000000007082 61.0
HFD2_k127_4527215_2 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 373.0
HFD2_k127_4527215_3 PFAM oxidoreductase FAD NAD(P)-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006956 311.0
HFD2_k127_4527215_4 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 292.0
HFD2_k127_4527215_5 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001198 277.0
HFD2_k127_4527215_6 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000238 285.0
HFD2_k127_4527215_7 Lysin motif K06194 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001287 271.0
HFD2_k127_4527215_9 similarity to GP 17427840 K07497 - - 0.000000000000000000000000000000000000000000000000007922 188.0
HFD2_k127_4532904_0 Glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2518.0
HFD2_k127_4532904_1 Large extracellular alpha-helical protein K09607 - - 0.0 1289.0
HFD2_k127_4532904_10 ABC transporter C-terminal domain K06158 - - 1.883e-271 849.0
HFD2_k127_4532904_11 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 2.608e-267 833.0
HFD2_k127_4532904_12 Glutamate synthase K00266 - 1.4.1.13,1.4.1.14 2.137e-258 808.0
HFD2_k127_4532904_13 PFAM Pyridoxal-dependent decarboxylase K01593 - 4.1.1.105,4.1.1.28 2.229e-230 728.0
HFD2_k127_4532904_14 Polysulphide reductase, NrfD K00185 - - 7.581e-225 705.0
HFD2_k127_4532904_15 AMP-binding enzyme C-terminal domain - - - 3.369e-222 701.0
HFD2_k127_4532904_16 Receptor family ligand binding region K01999 - - 1.467e-195 648.0
HFD2_k127_4532904_17 Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 592.0
HFD2_k127_4532904_18 two component, sigma54 specific, transcriptional regulator, Fis family K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006913 629.0
HFD2_k127_4532904_19 PFAM 4-hydroxyphenylacetate 3-hydroxylase N terminal K14534 - 4.2.1.120,5.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 553.0
HFD2_k127_4532904_2 Belongs to the ClpA ClpB family K03694 - - 0.0 1227.0
HFD2_k127_4532904_20 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00627,K00658 - 2.3.1.12,2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 474.0
HFD2_k127_4532904_21 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 471.0
HFD2_k127_4532904_22 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004432 457.0
HFD2_k127_4532904_23 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003166 451.0
HFD2_k127_4532904_24 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003941 447.0
HFD2_k127_4532904_25 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009031 428.0
HFD2_k127_4532904_26 Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP- dependent clade X sub-subfamily K00850 - 2.7.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 434.0
HFD2_k127_4532904_27 HAMP domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 428.0
HFD2_k127_4532904_28 DNA recombination protein RmuC K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005473 427.0
HFD2_k127_4532904_29 PFAM ATP-binding region, ATPase domain protein K07709 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 424.0
HFD2_k127_4532904_3 iron-sulfur binding K00184 - - 0.0 1115.0
HFD2_k127_4532904_30 PFAM Cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005096 412.0
HFD2_k127_4532904_31 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 406.0
HFD2_k127_4532904_32 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 399.0
HFD2_k127_4532904_33 Putative zinc-finger K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004129 401.0
HFD2_k127_4532904_34 PFAM ABC transporter K01990,K01992,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000072 430.0
HFD2_k127_4532904_35 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 411.0
HFD2_k127_4532904_36 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 380.0
HFD2_k127_4532904_37 Acyl-CoA thioesterase K10805 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 378.0
HFD2_k127_4532904_38 cytochrome c biogenesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 376.0
HFD2_k127_4532904_39 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 375.0
HFD2_k127_4532904_4 Von Willebrand factor type A K07114 - - 0.0 1083.0
HFD2_k127_4532904_40 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 383.0
HFD2_k127_4532904_41 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007873 351.0
HFD2_k127_4532904_42 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 350.0
HFD2_k127_4532904_43 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005014 355.0
HFD2_k127_4532904_44 epimerase dehydratase K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008214 346.0
HFD2_k127_4532904_45 PFAM secretion protein HlyD family protein K01993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 342.0
HFD2_k127_4532904_46 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000242 329.0
HFD2_k127_4532904_47 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009655 341.0
HFD2_k127_4532904_48 cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005913 339.0
HFD2_k127_4532904_49 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 341.0
HFD2_k127_4532904_5 ATP-dependent helicase HrpB K03579 - 3.6.4.13 0.0 1069.0
HFD2_k127_4532904_50 Exonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 292.0
HFD2_k127_4532904_51 Von Willebrand factor type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009847 295.0
HFD2_k127_4532904_52 UbiA prenyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006073 287.0
HFD2_k127_4532904_53 amino acid K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008385 300.0
HFD2_k127_4532904_54 Amino acid amide ABC transporter ATP-binding protein 2, HAAT family K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006773 290.0
HFD2_k127_4532904_55 Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001811 257.0
HFD2_k127_4532904_56 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000001847 251.0
HFD2_k127_4532904_57 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000006754 238.0
HFD2_k127_4532904_58 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000511 245.0
HFD2_k127_4532904_59 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000008752 228.0
HFD2_k127_4532904_6 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298 - 1.10.3.10,1.9.3.1 1.74e-291 903.0
HFD2_k127_4532904_60 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000009965 222.0
HFD2_k127_4532904_61 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000001708 237.0
HFD2_k127_4532904_62 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000001875 222.0
HFD2_k127_4532904_63 Appr-1'-p processing enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000003898 234.0
HFD2_k127_4532904_65 Von Willebrand factor type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000105 216.0
HFD2_k127_4532904_66 signal sequence binding - - - 0.000000000000000000000000000000000000000000000000000000002827 214.0
HFD2_k127_4532904_67 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000008308 206.0
HFD2_k127_4532904_68 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000003359 205.0
HFD2_k127_4532904_69 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.00000000000000000000000000000000000000000000000001329 203.0
HFD2_k127_4532904_7 PFAM aldehyde oxidase and xanthine dehydrogenase a b hammerhead - - - 8.383e-286 895.0
HFD2_k127_4532904_70 Protein of unknown function (DUF3341) - - - 0.000000000000000000000000000000000000000000000003463 194.0
HFD2_k127_4532904_71 - - - - 0.00000000000000000000000000000000000000003619 168.0
HFD2_k127_4532904_72 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000000000000000007733 147.0
HFD2_k127_4532904_73 ATP-independent chaperone mediated protein folding - - - 0.000000000000000000000000000000000001114 150.0
HFD2_k127_4532904_75 PFAM Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000003187 118.0
HFD2_k127_4532904_76 CoA binding domain - - - 0.0000000000000000000002826 103.0
HFD2_k127_4532904_78 - - - - 0.0000000000000000001601 91.0
HFD2_k127_4532904_8 dehydrogenase e1 component K00164 - 1.2.4.2 2.403e-285 921.0
HFD2_k127_4532904_80 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02022,K16922,K20345 - - 0.000000000002576 69.0
HFD2_k127_4532904_9 xanthine dehydrogenase activity K04108 - 1.3.7.9 2.043e-272 867.0
HFD2_k127_4590941_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1475.0
HFD2_k127_4590941_1 Maltogenic Amylase, C-terminal domain K05341,K05343 - 2.4.1.4,3.2.1.1,5.4.99.16 6.67e-282 882.0
HFD2_k127_4590941_10 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000009456 221.0
HFD2_k127_4590941_11 fmn reductase - - - 0.000000000000000000000000000000000000000000000000000000000002939 215.0
HFD2_k127_4590941_12 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000405 206.0
HFD2_k127_4590941_13 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000001467 187.0
HFD2_k127_4590941_14 PFAM Conserved TM helix repeat-containing protein - - - 0.000000000000000000000000000000000000000000206 169.0
HFD2_k127_4590941_15 CoA binding domain - - - 0.00000000000000000000000000000000000000002694 165.0
HFD2_k127_4590941_16 Soluble P-type ATPase - - - 0.0000000000000000000000000000000000001064 149.0
HFD2_k127_4590941_17 DDE superfamily endonuclease - - - 0.000000000000000000000000000000000001248 141.0
HFD2_k127_4590941_18 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000002447 121.0
HFD2_k127_4590941_19 - - - - 0.00000000000000000000000000003117 138.0
HFD2_k127_4590941_2 Belongs to the sigma-70 factor family. ECF subfamily - - - 1.345e-223 701.0
HFD2_k127_4590941_20 Unextendable partial coding region - - - 0.000000000000000276 83.0
HFD2_k127_4590941_21 YndJ-like protein - - - 0.0000000008648 70.0
HFD2_k127_4590941_3 4-alpha-glucanotransferase K00705 - 2.4.1.25 1.67e-204 652.0
HFD2_k127_4590941_4 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 587.0
HFD2_k127_4590941_5 Natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006631 505.0
HFD2_k127_4590941_6 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008275 437.0
HFD2_k127_4590941_7 glycosyl transferase family 2 K21349 - 2.4.1.268 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 344.0
HFD2_k127_4590941_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008566 330.0
HFD2_k127_4590941_9 MgtE intracellular N domain K02000,K05847 - 3.6.3.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000001427 294.0
HFD2_k127_4603239_0 FAD linked oxidases, C-terminal domain K18930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 578.0
HFD2_k127_4603239_1 3-demethylubiquinone-9 3-methyltransferase - - - 0.00000000000172 68.0
HFD2_k127_4617254_0 CoA-substrate-specific enzyme activase - - - 0.0 1692.0
HFD2_k127_4617254_1 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 2.738e-250 794.0
HFD2_k127_4617254_10 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 536.0
HFD2_k127_4617254_11 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 514.0
HFD2_k127_4617254_12 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009323 476.0
HFD2_k127_4617254_13 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008172 432.0
HFD2_k127_4617254_14 Pyridoxal-phosphate dependent enzyme K12339 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 413.0
HFD2_k127_4617254_15 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005383 420.0
HFD2_k127_4617254_16 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007913 421.0
HFD2_k127_4617254_17 6-phosphogluconate dehydrogenase K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 429.0
HFD2_k127_4617254_18 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002791 383.0
HFD2_k127_4617254_19 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006466 386.0
HFD2_k127_4617254_2 heat shock protein binding - - - 2.275e-227 721.0
HFD2_k127_4617254_20 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008227 350.0
HFD2_k127_4617254_21 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 317.0
HFD2_k127_4617254_23 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001004 276.0
HFD2_k127_4617254_24 heat shock protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004319 296.0
HFD2_k127_4617254_25 GAF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003768 267.0
HFD2_k127_4617254_26 Bacterial extracellular solute-binding protein K10938 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004215 271.0
HFD2_k127_4617254_27 Cobalamin (Vitamin B12) biosynthesis CbiM protein K02007 - - 0.00000000000000000000000000000000000000000000000000000000000000001541 238.0
HFD2_k127_4617254_28 ATPases associated with a variety of cellular activities K02006,K02008 - - 0.00000000000000000000000000000000000000000000000000000000000001482 241.0
HFD2_k127_4617254_29 - - - - 0.00000000000000000000000000000000000000000000000000000000000006991 228.0
HFD2_k127_4617254_3 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 2.232e-224 722.0
HFD2_k127_4617254_30 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.0000000000000000000000000000000000000000000000000000001795 221.0
HFD2_k127_4617254_31 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000004698 204.0
HFD2_k127_4617254_32 Belongs to the Dps family K04047 - - 0.0000000000000000000000000000000000000000000000000001047 191.0
HFD2_k127_4617254_33 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000002053 184.0
HFD2_k127_4617254_34 Mov34 MPN PAD-1 - - - 0.00000000000000000000000000000000000000003753 159.0
HFD2_k127_4617254_35 Acid phosphatase homologues K19302 - 3.6.1.27 0.0000000000000000000000000000000000001788 152.0
HFD2_k127_4617254_36 Cobalt transport protein K02008 - - 0.00000000000000000000000000000000001314 154.0
HFD2_k127_4617254_37 cyclic nucleotide-binding K10914 - - 0.0000000000000000000000000000000001149 145.0
HFD2_k127_4617254_38 ThiS family K03636 - - 0.000000000000000000000000000002584 123.0
HFD2_k127_4617254_39 Protein of unknown function (DUF421) - - - 0.000000000000000000000000000005455 130.0
HFD2_k127_4617254_4 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 646.0
HFD2_k127_4617254_41 Ferric uptake regulator family K09825 - - 0.00000000000000000000000000002181 121.0
HFD2_k127_4617254_42 COG0725 ABC-type molybdate transport system, periplasmic component K02020 - - 0.00000000000004068 83.0
HFD2_k127_4617254_43 Lecithin retinol acyltransferase - - - 0.00000001895 63.0
HFD2_k127_4617254_5 Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 567.0
HFD2_k127_4617254_6 PFAM UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 565.0
HFD2_k127_4617254_7 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005233 557.0
HFD2_k127_4617254_8 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007871 543.0
HFD2_k127_4617254_9 cytochrome c biogenesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000466 540.0
HFD2_k127_4628160_0 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 410.0
HFD2_k127_4628160_1 Two component signalling adaptor domain K03408 - - 0.00000000000000000000000000000000000000000002534 179.0
HFD2_k127_4628160_2 Two component signalling adaptor domain K03408 - - 0.00000000000000000000000000000001544 137.0
HFD2_k127_4730162_0 - - - - 0.00000000000000000000000000000000003541 137.0
HFD2_k127_4730162_1 DNA-templated transcription, initiation K01607,K03088 - 4.1.1.44 0.000000000000000000007572 99.0
HFD2_k127_4730162_2 Protein of unknown function (DUF2892) - - - 0.000000000000000225 90.0
HFD2_k127_4769991_0 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 479.0
HFD2_k127_4769991_1 Sodium:solute symporter family K14393 - - 0.000000000000000000000000000000000000000000000000001313 184.0
HFD2_k127_4769991_2 Pyridoxal-phosphate dependent enzyme K01697 - 4.2.1.22 0.0000000000000000000000008489 109.0
HFD2_k127_4771659_0 Phosphoribosyl transferase domain K07100 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 365.0
HFD2_k127_4771659_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000006971 122.0
HFD2_k127_4781359_0 Putative glutamine amidotransferase - - - 0.0 1031.0
HFD2_k127_4781359_1 DbpA RNA binding domain K03732,K05592 - 3.6.4.13 1.416e-255 803.0
HFD2_k127_4781359_10 Ferredoxin - - - 0.000000000000000000000000000000000000000000002313 166.0
HFD2_k127_4781359_13 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00615,K00616 - 2.2.1.1,2.2.1.2 0.0004226 45.0
HFD2_k127_4781359_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005093 492.0
HFD2_k127_4781359_3 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005487 431.0
HFD2_k127_4781359_4 HAD-hyrolase-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 435.0
HFD2_k127_4781359_5 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008675 450.0
HFD2_k127_4781359_6 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 380.0
HFD2_k127_4781359_7 Domain of unknown function (DUF4159) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009738 380.0
HFD2_k127_4781359_8 Short-chain dehydrogenase reductase SDR K00059,K00076,K00216,K03366,K13774,K18337 - 1.1.1.100,1.1.1.159,1.1.1.173,1.1.1.304,1.1.1.377,1.1.1.378,1.1.1.76,1.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008224 374.0
HFD2_k127_4781359_9 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 298.0
HFD2_k127_483155_0 zinc-ribbon domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 603.0
HFD2_k127_483155_1 GDP-mannose 4,6 dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 480.0
HFD2_k127_483155_2 Acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004314 414.0
HFD2_k127_483155_3 Selenocysteine-specific translation elongation factor K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 370.0
HFD2_k127_483155_4 Hsp33 protein K04083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 361.0
HFD2_k127_483155_5 Phosphoribosyl transferase domain K07101 - - 0.000000000000000000000000000000000000000000000000000000000000006739 222.0
HFD2_k127_4851356_0 Cysteine-rich domain K00113 - 1.1.5.3 1.913e-235 738.0
HFD2_k127_4851356_1 dioxygenase K00457,K16421 - 1.13.11.27,1.13.11.46 3.872e-205 642.0
HFD2_k127_4851356_10 Universal stress protein family - - - 0.0000000000000000000000000000000000000000000000000000002154 199.0
HFD2_k127_4851356_11 Prokaryotic diacylglycerol kinase K00901 - 2.7.1.107 0.00000000000000000000000000000000000302 145.0
HFD2_k127_4851356_2 DnaJ molecular chaperone homology domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004486 499.0
HFD2_k127_4851356_3 Fumarylacetoacetate (FAA) hydrolase family K16171 - 3.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 482.0
HFD2_k127_4851356_4 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 451.0
HFD2_k127_4851356_5 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003133 432.0
HFD2_k127_4851356_6 RarD protein K05786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004687 317.0
HFD2_k127_4851356_7 maleylacetoacetate isomerase K01800,K01801 - 5.2.1.2,5.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000004582 277.0
HFD2_k127_4851356_8 Protein of unknown function (DUF3501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006078 250.0
HFD2_k127_4851356_9 Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.0000000000000000000000000000000000000000000000000000000000000000000000007191 248.0
HFD2_k127_4856111_0 Belongs to the FPP GGPP synthase family K00805,K02523 - 2.5.1.30,2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004086 470.0
HFD2_k127_4856111_1 PFAM nickel-dependent hydrogenase, large subunit K00436 - 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 490.0
HFD2_k127_4856111_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 341.0
HFD2_k127_4856111_3 PFAM NADH ubiquinone oxidoreductase, subunit G K05588 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000002231 235.0
HFD2_k127_4856111_4 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K18007 - 1.12.1.2 0.0000000000000000000000000000000000000000004382 173.0
HFD2_k127_4856111_5 PFAM ATP-binding region, ATPase domain protein K02482 - 2.7.13.3 0.0000007445 57.0
HFD2_k127_4870284_0 ABC-type sugar transport system periplasmic component K17315 - - 8.37e-215 672.0
HFD2_k127_4870284_1 Domain of unknown function (DUF4037) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003881 246.0
HFD2_k127_4870284_2 Response regulator, receiver K03413 - - 0.0000000000000009228 79.0
HFD2_k127_489461_0 Single Cache domain 2 - - - 0.0000000000000000000000000000000000000000000000000000000000004917 226.0
HFD2_k127_489461_1 domain, Protein K01179 - 3.2.1.4 0.0000000000000000000000000001225 122.0
HFD2_k127_489461_2 PFAM Myo-inositol catabolism IolB domain protein K03337 - 5.3.1.30 0.000000000000000000005986 93.0
HFD2_k127_489461_4 cAMP biosynthetic process - - - 0.000001845 60.0
HFD2_k127_49431_0 Elongator protein 3, MiaB family, Radical SAM - - - 3.348e-281 888.0
HFD2_k127_49431_1 Class II Aldolase and Adducin N-terminal domain - - - 1.661e-271 856.0
HFD2_k127_49431_10 CoA binding domain K06929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007161 243.0
HFD2_k127_49431_11 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000000000000000000000003843 234.0
HFD2_k127_49431_12 Yip1 domain - - - 0.00000000000000000000000000000000000000000000000000001265 196.0
HFD2_k127_49431_13 Kelch motif - - - 0.000000000000000000000000000000000000000000002918 174.0
HFD2_k127_49431_14 Protein of unknown function (DUF2892) - - - 0.00000000000003946 85.0
HFD2_k127_49431_17 OPT oligopeptide transporter protein - - - 0.0000009366 51.0
HFD2_k127_49431_2 COG2873 O-acetylhomoserine sulfhydrylase K01738,K01740 - 2.5.1.47,2.5.1.49 7.397e-215 698.0
HFD2_k127_49431_3 helix_turn_helix gluconate operon transcriptional repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006076 486.0
HFD2_k127_49431_4 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005213 477.0
HFD2_k127_49431_5 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005497 464.0
HFD2_k127_49431_6 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004165 398.0
HFD2_k127_49431_7 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 308.0
HFD2_k127_49431_8 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003664 291.0
HFD2_k127_49431_9 Pfam Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001452 285.0
HFD2_k127_4959935_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00322 - 1.6.1.1 1.023e-216 705.0
HFD2_k127_4959935_1 PFAM aminotransferase class I and II K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004066 588.0
HFD2_k127_4959935_2 succinyl-diaminopimelate desuccinylase K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 509.0
HFD2_k127_4959935_3 DUF3160 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 477.0
HFD2_k127_4959935_4 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 440.0
HFD2_k127_4959935_5 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000711 349.0
HFD2_k127_4959935_6 peroxiredoxin activity - - - 0.0000000000000000000000000000000000000002474 156.0
HFD2_k127_4963435_0 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004341 373.0
HFD2_k127_4963435_1 COG1233 Phytoene dehydrogenase and related proteins - - - 0.0000000000000000000000000000000000000000000000000000000001405 205.0
HFD2_k127_4963435_2 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.000000000000000000002201 109.0
HFD2_k127_4965007_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895,K01907 - 6.2.1.1,6.2.1.16 3.745e-271 844.0
HFD2_k127_4965007_1 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 3.125e-228 723.0
HFD2_k127_4965007_10 GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004675 356.0
HFD2_k127_4965007_11 Outer membrane efflux protein K12543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 330.0
HFD2_k127_4965007_12 ABC transporter K09817 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001497 283.0
HFD2_k127_4965007_13 Binding-protein-dependent transport system inner membrane component K02018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000195 284.0
HFD2_k127_4965007_14 ABC 3 transport family K09819,K11606,K11708,K11709 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002224 258.0
HFD2_k127_4965007_15 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001466 255.0
HFD2_k127_4965007_16 Belongs to the carbamate kinase family K00926 - 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000003623 248.0
HFD2_k127_4965007_17 Bacterial extracellular solute-binding protein K02020 - - 0.0000000000000000000000000000000000000000000000000000000000000002484 229.0
HFD2_k127_4965007_18 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.00000000000000000000000000000000000000000000000000000000000000102 225.0
HFD2_k127_4965007_19 PFAM AhpC TSA family - - - 0.00000000000000000000000000000000000000000000000000000000000003419 222.0
HFD2_k127_4965007_2 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006476 567.0
HFD2_k127_4965007_20 Protein of unknown function (DUF3014) - - - 0.0000000000000000000000000000000000000000000000000000000000274 217.0
HFD2_k127_4965007_21 PFAM Metal-dependent phosphohydrolase, HD K00951 - 2.7.6.5 0.00000000000000000000000000000000000000000000000000000003761 201.0
HFD2_k127_4965007_22 YhhN family - - - 0.00000000000000000000000000000000000000000000002533 181.0
HFD2_k127_4965007_23 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000003097 179.0
HFD2_k127_4965007_24 Urate oxidase N-terminal - - - 0.000000000000000000000000000000000000000003088 169.0
HFD2_k127_4965007_25 Hsp20/alpha crystallin family K13993 - - 0.00000000000000000000000000000000000000002086 159.0
HFD2_k127_4965007_26 Scavenger mRNA decapping enzyme C-term binding - - - 0.0000000000000000000000000000000000000002708 153.0
HFD2_k127_4965007_27 SnoaL-like domain - - - 0.000000000000000000000000000000004247 140.0
HFD2_k127_4965007_28 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627 - 2.3.1.12 0.000000000000000000000001901 106.0
HFD2_k127_4965007_29 - - - - 0.00000000000000000004929 98.0
HFD2_k127_4965007_3 CobW/HypB/UreG, nucleotide-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009735 506.0
HFD2_k127_4965007_4 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit K00162 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 510.0
HFD2_k127_4965007_5 ABC transporter K02017 - 3.6.3.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008987 466.0
HFD2_k127_4965007_6 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003292 451.0
HFD2_k127_4965007_7 Aminotransferase class-III K00819,K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.13,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009104 466.0
HFD2_k127_4965007_8 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00161,K00162,K11381,K21416 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003499 432.0
HFD2_k127_4965007_9 Serine Threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004933 382.0
HFD2_k127_5015099_0 glycogen debranching - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 304.0
HFD2_k127_5015099_1 water channel activity K02440,K06188 - - 0.00000000000000000000000000000000000000000000000000000000502 207.0
HFD2_k127_5015099_2 Glycogen debranching enzyme - - - 0.000000000000000000001256 104.0
HFD2_k127_5015099_3 water channel activity K02440,K06188 - - 0.000001919 51.0
HFD2_k127_5314957_0 Carbamoyl-phosphate synthetase ammonia chain K01955 - 6.3.5.5 0.0 1779.0
HFD2_k127_5314957_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1441.0
HFD2_k127_5314957_10 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 6.478e-246 764.0
HFD2_k127_5314957_11 Di-haem cytochrome c peroxidase - - - 1.829e-244 806.0
HFD2_k127_5314957_12 Belongs to the peptidase S16 family - - - 7.971e-242 773.0
HFD2_k127_5314957_13 Aminotransferase K00812 - 2.6.1.1 9.491e-219 683.0
HFD2_k127_5314957_14 pfam abc1 K03688 - - 8.455e-211 669.0
HFD2_k127_5314957_15 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 4.857e-208 712.0
HFD2_k127_5314957_16 Cytochrome c - - - 1.538e-207 652.0
HFD2_k127_5314957_17 PFAM Aminotransferase class I and II K10206,K14261 - 2.6.1.83 2.969e-205 645.0
HFD2_k127_5314957_18 peptidyl-tyrosine sulfation - - - 2.834e-199 680.0
HFD2_k127_5314957_19 serine threonine protein kinase K08884,K12132 - 2.7.11.1 2.379e-196 630.0
HFD2_k127_5314957_2 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0 1279.0
HFD2_k127_5314957_20 Periplasmic copper-binding protein (NosD) K07218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 612.0
HFD2_k127_5314957_21 xanthine dehydrogenase activity K07303 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009071 610.0
HFD2_k127_5314957_22 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 571.0
HFD2_k127_5314957_23 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 563.0
HFD2_k127_5314957_24 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 546.0
HFD2_k127_5314957_25 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009861 477.0
HFD2_k127_5314957_26 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007065 447.0
HFD2_k127_5314957_27 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003604 430.0
HFD2_k127_5314957_28 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 425.0
HFD2_k127_5314957_29 deoxyhypusine monooxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005428 426.0
HFD2_k127_5314957_3 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0 1215.0
HFD2_k127_5314957_31 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 391.0
HFD2_k127_5314957_32 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 404.0
HFD2_k127_5314957_33 ABC transporter K01990,K19340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000459 398.0
HFD2_k127_5314957_34 Cation efflux family K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 377.0
HFD2_k127_5314957_35 Belongs to the SUA5 family K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 359.0
HFD2_k127_5314957_36 ABC-2 family transporter protein K19341 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 371.0
HFD2_k127_5314957_37 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 394.0
HFD2_k127_5314957_38 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008647 350.0
HFD2_k127_5314957_39 Belongs to the pseudouridine synthase RsuA family K06178,K06182 - 5.4.99.21,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 368.0
HFD2_k127_5314957_4 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0 1101.0
HFD2_k127_5314957_40 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006144 352.0
HFD2_k127_5314957_41 acid phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009218 351.0
HFD2_k127_5314957_42 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004824 361.0
HFD2_k127_5314957_43 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 353.0
HFD2_k127_5314957_44 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 342.0
HFD2_k127_5314957_45 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 333.0
HFD2_k127_5314957_46 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 337.0
HFD2_k127_5314957_47 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005193 319.0
HFD2_k127_5314957_48 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003546 319.0
HFD2_k127_5314957_49 Pregnancy-associated plasma protein-A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008245 311.0
HFD2_k127_5314957_5 Cytochrome C oxidase subunit II, periplasmic domain K00376 - 1.7.2.4 0.0 1056.0
HFD2_k127_5314957_50 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 329.0
HFD2_k127_5314957_51 lipoprotein involved in nitrous oxide reduction - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008111 289.0
HFD2_k127_5314957_52 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001548 293.0
HFD2_k127_5314957_53 Mut7-C ubiquitin K09122 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002725 286.0
HFD2_k127_5314957_54 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000299 269.0
HFD2_k127_5314957_55 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007185 280.0
HFD2_k127_5314957_56 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000015 252.0
HFD2_k127_5314957_57 Isochorismatase family K08281 - 3.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000181 253.0
HFD2_k127_5314957_58 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000002383 251.0
HFD2_k127_5314957_59 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006842 240.0
HFD2_k127_5314957_6 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.0 1018.0
HFD2_k127_5314957_60 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000002564 242.0
HFD2_k127_5314957_61 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000000002693 243.0
HFD2_k127_5314957_62 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000001228 239.0
HFD2_k127_5314957_63 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000000000000000567 215.0
HFD2_k127_5314957_64 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000821 216.0
HFD2_k127_5314957_65 Pyruvate phosphate dikinase - - - 0.000000000000000000000000000000000000000000000000000001853 200.0
HFD2_k127_5314957_66 2Fe-2S -binding domain protein K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000002848 197.0
HFD2_k127_5314957_67 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.000000000000000000000000000000000000000000000000000007007 206.0
HFD2_k127_5314957_7 Transcriptional regulator - - - 3.688e-271 861.0
HFD2_k127_5314957_70 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000006664 191.0
HFD2_k127_5314957_71 lipoprotein involved in nitrous oxide reduction K19342 - - 0.00000000000000000000000000000000000000000000257 173.0
HFD2_k127_5314957_72 Integrin alpha (beta-propellor repeats). - - - 0.000000000000000000000000000000000000000003728 181.0
HFD2_k127_5314957_73 Beta-Ig-H3 fasciclin - - - 0.000000000000000000000000000000000000000008073 160.0
HFD2_k127_5314957_74 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000002246 154.0
HFD2_k127_5314957_75 - - - - 0.0000000000000000000000000000000000000008378 151.0
HFD2_k127_5314957_76 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.000000000000000000000000000000000000001033 169.0
HFD2_k127_5314957_77 Cold-shock protein K03704 - - 0.0000000000000000000000000000000007638 133.0
HFD2_k127_5314957_79 - - - - 0.0000000000000000000000000000002171 132.0
HFD2_k127_5314957_8 WD40-like Beta Propeller Repeat - - - 3.381e-269 862.0
HFD2_k127_5314957_81 Sigma-54 interaction domain K07713,K07714 - - 0.00000000000000000000000000007246 128.0
HFD2_k127_5314957_82 Catabolite gene activator and regulatory subunit of cAMP-dependent protein - - - 0.000000000000000000000000001484 132.0
HFD2_k127_5314957_89 Class III cytochrome C family - - - 0.000000000000002082 83.0
HFD2_k127_5314957_9 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 2.181e-247 777.0
HFD2_k127_5314957_90 Transcriptional regulator, BadM Rrf2 family - - - 0.00000000000000351 83.0
HFD2_k127_5314957_91 Universal stress protein family - - - 0.00000000000002879 87.0
HFD2_k127_5314957_94 - - - - 0.000004757 60.0
HFD2_k127_5314957_95 long-chain fatty acid transport protein - - - 0.000007811 56.0
HFD2_k127_5314957_96 DNA integration - - - 0.00009176 48.0
HFD2_k127_5314957_97 EamA-like transporter family - - - 0.0005876 47.0
HFD2_k127_5322835_0 May be involved in recombinational repair of damaged DNA K03631 - - 2.696e-226 716.0
HFD2_k127_5322835_1 AAA C-terminal domain K07478 - - 3.974e-210 668.0
HFD2_k127_5322835_10 protein phosphatase 2C domain protein K01090,K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 342.0
HFD2_k127_5322835_11 Bacterial capsule synthesis protein PGA_cap - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009232 325.0
HFD2_k127_5322835_12 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007692 275.0
HFD2_k127_5322835_13 phosphoglycolate phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001141 276.0
HFD2_k127_5322835_14 Uncharacterised protein family (UPF0227) K07000 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001095 266.0
HFD2_k127_5322835_15 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000008124 242.0
HFD2_k127_5322835_16 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000007814 217.0
HFD2_k127_5322835_17 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000000000000000000000000002321 179.0
HFD2_k127_5322835_18 cysteine-type peptidase activity K21471,K21473,K21687 - - 0.000000000000000000000000000000000000000002842 168.0
HFD2_k127_5322835_19 chaperone-mediated protein folding - - - 0.0000000000000000000000000000000001504 135.0
HFD2_k127_5322835_2 Histidine kinase A domain protein K02482 - 2.7.13.3 2.08e-209 663.0
HFD2_k127_5322835_3 Belongs to the D-alanine--D-alanine ligase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000839 628.0
HFD2_k127_5322835_4 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 407.0
HFD2_k127_5322835_5 Two component, sigma54 specific, transcriptional regulator, Fis family K02667,K07713,K07714,K19641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009953 402.0
HFD2_k127_5322835_6 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005032 374.0
HFD2_k127_5322835_7 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 369.0
HFD2_k127_5322835_8 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 354.0
HFD2_k127_5322835_9 Enoyl-(Acyl carrier protein) reductase K03793 - 1.5.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 347.0
HFD2_k127_5374716_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.0 1645.0
HFD2_k127_5374716_1 glycosyl transferase family K00697 - 2.4.1.15,2.4.1.347 2.471e-307 958.0
HFD2_k127_5374716_10 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000993 518.0
HFD2_k127_5374716_11 Sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 505.0
HFD2_k127_5374716_12 Organic Anion Transporter Polypeptide (OATP) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 476.0
HFD2_k127_5374716_13 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009656 471.0
HFD2_k127_5374716_14 Belongs to the metallo-dependent hydrolases superfamily. HutI family K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 452.0
HFD2_k127_5374716_15 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005779 451.0
HFD2_k127_5374716_16 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 439.0
HFD2_k127_5374716_17 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006709 465.0
HFD2_k127_5374716_18 Domains REC, sigma54 interaction, HTH8 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003593 427.0
HFD2_k127_5374716_19 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 407.0
HFD2_k127_5374716_2 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 1.7e-293 908.0
HFD2_k127_5374716_20 Domain of unknown function (DUF4178) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 403.0
HFD2_k127_5374716_21 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 343.0
HFD2_k127_5374716_22 SPFH domain-Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009041 344.0
HFD2_k127_5374716_23 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 334.0
HFD2_k127_5374716_24 Nad-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004145 310.0
HFD2_k127_5374716_25 Belongs to the arginase family K01479,K12255 - 3.5.3.7,3.5.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000004996 280.0
HFD2_k127_5374716_26 metalloendopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005057 256.0
HFD2_k127_5374716_27 Glycerate kinase K11529 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008887,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0071704,GO:1901564 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000002288 258.0
HFD2_k127_5374716_28 CYTH - - - 0.0000000000000000000000000000000000000000000000000000000000000000006298 248.0
HFD2_k127_5374716_29 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.000000000000000000000000000000000000000000000000003888 208.0
HFD2_k127_5374716_3 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01835 - 5.4.2.2 2.672e-263 820.0
HFD2_k127_5374716_30 PAP2 superfamily - - - 0.000000000000000000000000000000000000000000000000004823 197.0
HFD2_k127_5374716_32 - - - - 0.000000000000000000000000000000000000000000007552 177.0
HFD2_k127_5374716_33 adenosine 5'-monophosphoramidase activity - - - 0.000000000000000000000000000000000000000002857 171.0
HFD2_k127_5374716_34 Protein of unknown function (DUF2470) K07226 - - 0.00000000000000000000000000000000003429 146.0
HFD2_k127_5374716_36 TPR repeat - - - 0.0000000000000000000000000000001612 138.0
HFD2_k127_5374716_37 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.00000000000000000000000000007309 132.0
HFD2_k127_5374716_38 PFAM Transmembrane exosortase (Exosortase_EpsH) - - - 0.00000000000000000007034 102.0
HFD2_k127_5374716_4 Flavin containing amine oxidoreductase - - - 1.501e-254 794.0
HFD2_k127_5374716_40 Domain of Unknown Function (DUF350) - - - 0.000000000007694 72.0
HFD2_k127_5374716_5 Histidine kinase HAMP - - - 9.726e-194 617.0
HFD2_k127_5374716_6 Belongs to the GPI family K01810 - 5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002887 608.0
HFD2_k127_5374716_7 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005821 591.0
HFD2_k127_5374716_8 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 569.0
HFD2_k127_5374716_9 Cytochrome c3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 526.0
HFD2_k127_5380562_0 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002995 503.0
HFD2_k127_5380562_1 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009516 276.0
HFD2_k127_5383783_0 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000003739 149.0
HFD2_k127_5383783_1 Transcriptional regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000002465 120.0
HFD2_k127_5383783_2 ABC 3 transport family K09819,K11606,K11708,K11709 - - 0.000000000000000001035 88.0
HFD2_k127_5396395_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003166 599.0
HFD2_k127_5396395_1 acyl-coa dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 566.0
HFD2_k127_5396395_2 ArgK protein K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004954 475.0
HFD2_k127_5396395_3 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008068 360.0
HFD2_k127_5396395_4 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 337.0
HFD2_k127_5396395_5 methyltransferase activity K13613,K15677 - - 0.0000000000000000000000000000000000000000000000000000000000000000001311 238.0
HFD2_k127_5396395_6 B12 binding domain K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000000004078 239.0
HFD2_k127_5537969_0 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 466.0
HFD2_k127_5537969_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 352.0
HFD2_k127_5537969_3 - - - - 0.0000000000003349 79.0
HFD2_k127_5537969_4 OsmC-like protein - - - 0.000000000002794 70.0
HFD2_k127_5543675_0 Belongs to the hyi family K01816,K22131 - 5.3.1.22,5.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009049 386.0
HFD2_k127_5543675_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000284 253.0
HFD2_k127_5543675_2 PFAM Extracellular ligand-binding receptor - - - 0.00000000000000000000000000000000000000002342 163.0
HFD2_k127_5549405_0 Serine Threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006826 624.0
HFD2_k127_5549405_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.0000000000000000001066 89.0
HFD2_k127_557896_0 Peptidase family M3 K01392 - 3.4.24.15 1.783e-286 918.0
HFD2_k127_557896_1 SMART Elongator protein 3 MiaB NifB - - - 3.208e-212 676.0
HFD2_k127_557896_10 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 371.0
HFD2_k127_557896_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000007212 230.0
HFD2_k127_557896_12 energy transducer activity K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000321 222.0
HFD2_k127_557896_13 TIGRFAM hydro-lyase, Fe-S type, tartrate fumarate subfamily, beta subunit K01676,K01678 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000001169 215.0
HFD2_k127_557896_14 biopolymer transport protein K03559,K03560 - - 0.000000000000000000000000000000000000000000000000000000001026 207.0
HFD2_k127_557896_15 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000001931 203.0
HFD2_k127_557896_16 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.000000000000000000000000000000000000000000000000347 179.0
HFD2_k127_557896_17 metallopeptidase activity - - - 0.0000000000000000000000000000000000000003194 164.0
HFD2_k127_557896_18 PAS fold - - - 0.000000000000000000185 95.0
HFD2_k127_557896_2 Mitochondrial small ribosomal subunit Rsm22 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002953 545.0
HFD2_k127_557896_3 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007111 498.0
HFD2_k127_557896_4 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 432.0
HFD2_k127_557896_5 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004303 466.0
HFD2_k127_557896_6 nitric oxide dioxygenase activity K00523,K15983 - 1.14.13.142,1.17.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 399.0
HFD2_k127_557896_7 MotA TolQ ExbB proton channel K03561,K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009411 369.0
HFD2_k127_557896_8 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003929 363.0
HFD2_k127_557896_9 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 362.0
HFD2_k127_5582672_0 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005334 328.0
HFD2_k127_5582672_1 family UPF0324 - - - 0.00000004052 54.0
HFD2_k127_5597618_0 OPT oligopeptide transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008708 481.0
HFD2_k127_5597618_1 glutathione-regulated potassium exporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004109 415.0
HFD2_k127_5597618_10 - - - - 0.0000002455 57.0
HFD2_k127_5597618_2 PFAM sodium calcium exchanger membrane region K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007204 367.0
HFD2_k127_5597618_3 Belongs to the ompA family K03286 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006113 374.0
HFD2_k127_5597618_4 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000000004762 233.0
HFD2_k127_5597618_5 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000000000003678 194.0
HFD2_k127_5597618_6 Protein of unknown function (DUF1460) - - - 0.0000000000000000000000000000000000000000000000000006836 199.0
HFD2_k127_5597618_8 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000001796 147.0
HFD2_k127_5597618_9 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000002299 98.0
HFD2_k127_5717668_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 420.0
HFD2_k127_5717668_1 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006382 299.0
HFD2_k127_5717668_2 PAS domain - - - 0.00000000000000000000000000000000000000000000000000000000003733 213.0
HFD2_k127_5786974_0 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000546 446.0
HFD2_k127_5786974_1 peptidyl-prolyl isomerase K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 421.0
HFD2_k127_5786974_2 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 326.0
HFD2_k127_5786974_3 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002735 260.0
HFD2_k127_5786974_4 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001738 268.0
HFD2_k127_5786974_5 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001626 246.0
HFD2_k127_5852190_0 protein containing caspase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003357 244.0
HFD2_k127_5852190_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000007244 189.0
HFD2_k127_5859528_0 Peptidase M1 membrane alanine aminopeptidase K01256,K08776 - 3.4.11.2 1.252e-314 992.0
HFD2_k127_5859528_1 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 2.945e-291 911.0
HFD2_k127_5859528_10 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000001792 175.0
HFD2_k127_5859528_11 TIGRFAM Molybdopterin-guanine dinucleotide biosynthesis protein B K03753 - - 0.0000000000000000000000000000000000000000001059 182.0
HFD2_k127_5859528_12 Universal stress protein family - - - 0.00000000000000000000000000000000000002038 148.0
HFD2_k127_5859528_13 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000003989 79.0
HFD2_k127_5859528_2 Sigma-54 interaction domain - - - 1.242e-236 741.0
HFD2_k127_5859528_3 Protoglobin - GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005515,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0019825,GO:0020037,GO:0023014,GO:0023052,GO:0035556,GO:0036094,GO:0036211,GO:0042802,GO:0042803,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046906,GO:0046983,GO:0048037,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0097159,GO:0140096,GO:1901363,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000781 500.0
HFD2_k127_5859528_4 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 423.0
HFD2_k127_5859528_5 Crp-like helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 356.0
HFD2_k127_5859528_6 Phospholipase D Active site motif K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004 337.0
HFD2_k127_5859528_7 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004165 296.0
HFD2_k127_5859528_8 PFAM Hemerythrin HHE cation binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000156 222.0
HFD2_k127_5859528_9 CBS domain K04767,K07168,K07182 - - 0.000000000000000000000000000000000000000000000000001624 194.0
HFD2_k127_5903637_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008564 552.0
HFD2_k127_5903637_1 Alcohol dehydrogenase GroES domain protein K19745 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 487.0
HFD2_k127_5903637_2 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000001436 233.0
HFD2_k127_5903637_3 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000002305 163.0
HFD2_k127_5903637_4 Peptidase, M61 - - - 0.000000000000000000000000000002072 124.0
HFD2_k127_5903637_5 PFAM Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000001094 119.0
HFD2_k127_5979291_0 Heat shock 70 kDa protein K04043 - - 0.0 1042.0
HFD2_k127_5979291_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0 1019.0
HFD2_k127_5979291_10 two component, sigma54 specific, transcriptional regulator, Fis family - - - 7.475e-236 761.0
HFD2_k127_5979291_11 diguanylate cyclase - - - 1.721e-206 681.0
HFD2_k127_5979291_12 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 1.123e-202 636.0
HFD2_k127_5979291_13 GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003572 601.0
HFD2_k127_5979291_14 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 561.0
HFD2_k127_5979291_15 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 508.0
HFD2_k127_5979291_16 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004259 506.0
HFD2_k127_5979291_17 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003867 477.0
HFD2_k127_5979291_18 Diacylglycerol kinase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 454.0
HFD2_k127_5979291_19 signal peptide peptidase SppA, 36K type K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 439.0
HFD2_k127_5979291_2 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 5.443e-312 989.0
HFD2_k127_5979291_20 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 406.0
HFD2_k127_5979291_21 Asparagine synthase K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009663 396.0
HFD2_k127_5979291_22 Belongs to the RimK family K05844 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016874,GO:0016879,GO:0016881,GO:0018169,GO:0018410,GO:0019538,GO:0031668,GO:0033554,GO:0036211,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0070739,GO:0071496,GO:0071704,GO:0140096,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007763 395.0
HFD2_k127_5979291_23 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 379.0
HFD2_k127_5979291_24 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008453 366.0
HFD2_k127_5979291_25 Bacterial regulatory protein, Fis family K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 366.0
HFD2_k127_5979291_26 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005334 346.0
HFD2_k127_5979291_27 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 336.0
HFD2_k127_5979291_28 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 327.0
HFD2_k127_5979291_29 PFAM iron dependent repressor K03709 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 311.0
HFD2_k127_5979291_3 Arginyl tRNA synthetase N terminal dom K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 2.05e-290 903.0
HFD2_k127_5979291_30 deaminase K01493 - 3.5.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000469 292.0
HFD2_k127_5979291_31 cell septum assembly - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 301.0
HFD2_k127_5979291_32 domain protein K21029,K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 287.0
HFD2_k127_5979291_33 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000181 299.0
HFD2_k127_5979291_34 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004958 279.0
HFD2_k127_5979291_35 Protein similar to CwfJ C-terminus 1 K19710 - 2.7.7.53 0.0000000000000000000000000000000000000000000000000000000000000000000000007604 249.0
HFD2_k127_5979291_36 dipeptide transport K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003657 254.0
HFD2_k127_5979291_39 Catalyzes the synthesis of activated sulfate K00390,K00860 - 1.8.4.10,1.8.4.8,2.7.1.25 0.0000000000000000000000000000000000000000000000000000000002206 210.0
HFD2_k127_5979291_4 PrkA serine protein kinase C-terminal domain - - - 1.273e-288 910.0
HFD2_k127_5979291_40 Mannose-6-phosphate isomerase - - - 0.00000000000000000000000000000000000000000000000000000003593 198.0
HFD2_k127_5979291_41 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC K06148,K16012 - - 0.00000000000000000000000000000000000000000000000000005442 207.0
HFD2_k127_5979291_42 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000000000000000000000321 188.0
HFD2_k127_5979291_43 Involved in molybdopterin and thiamine biosynthesis, family 2 - - - 0.000000000000000000000000000000000000000000000000006055 194.0
HFD2_k127_5979291_45 PFAM Radical SAM domain protein K06871 - - 0.0000000000000000000000000000000000006104 157.0
HFD2_k127_5979291_46 peptidoglycan binding K02453,K03749 GO:0000910,GO:0003674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0009987,GO:0022402,GO:0030428,GO:0032153,GO:0032506,GO:0042834,GO:0044464,GO:0051301,GO:0097367 - 0.000000000000000000000000000000000001918 146.0
HFD2_k127_5979291_48 photoreceptor activity K11527 - 2.7.13.3 0.0000000000000000000000000000005482 131.0
HFD2_k127_5979291_5 FAD dependent oxidoreductase K07137 - - 1.179e-255 802.0
HFD2_k127_5979291_52 Belongs to the sulfur carrier protein TusA family - - - 0.000000000000000000000004944 119.0
HFD2_k127_5979291_53 Preprotein translocase SecG subunit K03075 - - 0.0000000000000000000008251 112.0
HFD2_k127_5979291_54 Regulatory protein, FmdB family - - - 0.00000000000000000004897 98.0
HFD2_k127_5979291_55 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000000002167 102.0
HFD2_k127_5979291_58 cell cycle K05589,K12065,K13052 - - 0.0000000000000001468 83.0
HFD2_k127_5979291_59 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000005139 83.0
HFD2_k127_5979291_6 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 1.354e-254 798.0
HFD2_k127_5979291_61 Glutaredoxin K03676 - - 0.00000000000004047 73.0
HFD2_k127_5979291_63 - - - - 0.00003292 49.0
HFD2_k127_5979291_64 Molydopterin dinucleotide binding domain K07812 - 1.7.2.3 0.0007623 51.0
HFD2_k127_5979291_7 Heat shock 70 kDa protein K04043 - - 5.513e-252 784.0
HFD2_k127_5979291_8 Large family of predicted nucleotide-binding domains K07175 - - 1.813e-239 747.0
HFD2_k127_5979291_9 Heat shock 70 kDa protein - - - 6.732e-236 755.0
HFD2_k127_606977_0 DEAD DEAH box helicase - - - 0.0 1207.0
HFD2_k127_606977_1 Biopterin-dependent aromatic amino acid hydroxylase K00500 - 1.14.16.1 1.536e-200 637.0
HFD2_k127_606977_2 transmembrane signaling receptor activity K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004506 423.0
HFD2_k127_606977_3 LD-carboxypeptidase K01297 - 3.4.17.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 381.0
HFD2_k127_606977_4 beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 367.0
HFD2_k127_606977_5 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000001083 244.0
HFD2_k127_606977_6 Glutathione S-transferase K00799 GO:0000302,GO:0003674,GO:0003824,GO:0004364,GO:0006950,GO:0006979,GO:0008150,GO:0009636,GO:0010035,GO:0016740,GO:0016765,GO:0042221,GO:0042493,GO:0042542,GO:0046677,GO:0050896,GO:1901700 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000001878 241.0
HFD2_k127_606977_7 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000000000000000000000000006061 233.0
HFD2_k127_606977_8 - - - - 0.00000000000000000000000000000000001274 145.0
HFD2_k127_6123597_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1510.0
HFD2_k127_6123597_1 glutaminyl-tRNA K01886 - 6.1.1.18 0.0 1142.0
HFD2_k127_6123597_10 iron ion homeostasis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 526.0
HFD2_k127_6123597_11 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005845 444.0
HFD2_k127_6123597_12 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007232 414.0
HFD2_k127_6123597_13 NAD(P)-binding Rossmann-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 415.0
HFD2_k127_6123597_14 Double sensory domain of two-component sensor kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 366.0
HFD2_k127_6123597_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008861 331.0
HFD2_k127_6123597_16 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004589 268.0
HFD2_k127_6123597_17 PFAM Glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001173 284.0
HFD2_k127_6123597_18 MgtC family K07507 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001416 249.0
HFD2_k127_6123597_19 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000005818 220.0
HFD2_k127_6123597_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1040.0
HFD2_k127_6123597_20 - - - - 0.0000000000000000000000000000000000000000000000000000000006877 214.0
HFD2_k127_6123597_21 Pectinacetylesterase - - - 0.000000000000000000000000000000000000000000000000000000002066 224.0
HFD2_k127_6123597_22 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000000000000001336 198.0
HFD2_k127_6123597_24 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.00000000000000000000000000000000000000000004689 177.0
HFD2_k127_6123597_25 mechanosensitive ion channel activity K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.000000000000000000000000000000000000000001094 163.0
HFD2_k127_6123597_26 YCII-related domain K09780 - - 0.000000000000000000000000000000005694 133.0
HFD2_k127_6123597_27 PFAM Class I peptide chain release factor K15034 - - 0.0000000000000000000000000000005967 126.0
HFD2_k127_6123597_29 Roadblock/LC7 domain K07131 - - 0.000000000000000126 92.0
HFD2_k127_6123597_3 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 1.052e-306 962.0
HFD2_k127_6123597_30 Protein of unknown function (DUF3365) - - - 0.00000000000004623 85.0
HFD2_k127_6123597_32 PFAM 2-nitropropane dioxygenase NPD K00459 - 1.13.12.16 0.0000000003468 71.0
HFD2_k127_6123597_4 Sodium/hydrogen exchanger family K03455 - - 4.969e-245 775.0
HFD2_k127_6123597_5 peptidase U62 modulator of DNA gyrase - - - 2.434e-239 754.0
HFD2_k127_6123597_6 Fungalysin metallopeptidase (M36) - - - 3.091e-238 781.0
HFD2_k127_6123597_7 Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009221 609.0
HFD2_k127_6123597_8 Fungal trichothecene efflux pump (TRI12) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 605.0
HFD2_k127_6123597_9 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004765 537.0
HFD2_k127_6130226_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005968 400.0
HFD2_k127_6130226_1 ATPases associated with a variety of cellular activities K02028,K10004 - 3.6.3.21 0.000000000000000000000004965 101.0
HFD2_k127_6130226_2 - - - - 0.00000003111 63.0
HFD2_k127_6130226_3 - - - - 0.000003698 60.0
HFD2_k127_615659_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.0 1023.0
HFD2_k127_615659_1 ATP-binding region ATPase domain protein K03407,K13490 - 2.7.13.3 1.955e-270 850.0
HFD2_k127_615659_10 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 458.0
HFD2_k127_615659_11 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 443.0
HFD2_k127_615659_12 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 394.0
HFD2_k127_615659_13 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 388.0
HFD2_k127_615659_14 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 365.0
HFD2_k127_615659_15 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 360.0
HFD2_k127_615659_16 Aldo/keto reductase family K05275 - 1.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 358.0
HFD2_k127_615659_17 Belongs to the D-glutamate cyclase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 342.0
HFD2_k127_615659_18 TIGRFAM urea amidolyase related protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 313.0
HFD2_k127_615659_19 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 303.0
HFD2_k127_615659_2 twitching motility protein K02669 - - 3.324e-201 661.0
HFD2_k127_615659_20 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000363 278.0
HFD2_k127_615659_21 Allophanate hydrolase subunit 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002355 269.0
HFD2_k127_615659_22 Belongs to the UPF0271 (lamB) family K07160 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002124 281.0
HFD2_k127_615659_23 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007315 274.0
HFD2_k127_615659_24 branched-chain amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007283 259.0
HFD2_k127_615659_25 PFAM thioesterase superfamily K02614 - - 0.00000000000000000000000000000000000000000000000000005391 194.0
HFD2_k127_615659_27 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.000000000000000000000000000000000000000000001506 176.0
HFD2_k127_615659_28 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000000002261 156.0
HFD2_k127_615659_3 Type II secretion system (T2SS), protein F K02653 - - 1.353e-198 625.0
HFD2_k127_615659_31 Type IV Pilus-assembly protein W K02672 - - 0.000000000000000000000002951 119.0
HFD2_k127_615659_34 protein transport across the cell outer membrane K02246,K02457,K02459,K02672,K08084 - - 0.0000001464 61.0
HFD2_k127_615659_4 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00756,K00758 - 2.4.2.2,2.4.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005958 585.0
HFD2_k127_615659_5 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 519.0
HFD2_k127_615659_6 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 531.0
HFD2_k127_615659_7 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004197 497.0
HFD2_k127_615659_8 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009978 535.0
HFD2_k127_615659_9 Methyl-accepting chemotaxis protein K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003575 477.0
HFD2_k127_6305753_0 NUDIX domain - - - 0.00000000000000000000000000000000000000000000000000000003306 201.0
HFD2_k127_6305753_1 Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.00000000000000000000000000000000000000000000000000002448 197.0
HFD2_k127_6305753_2 SnoaL-like domain - - - 0.000000000000000000000000000001675 124.0
HFD2_k127_6332933_0 protein conserved in bacteria K11891 - - 0.0 1056.0
HFD2_k127_6332933_1 oligopeptide transporter, OPT family - - - 0.0 1041.0
HFD2_k127_6332933_10 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004763 560.0
HFD2_k127_6332933_11 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 542.0
HFD2_k127_6332933_12 N-succinyltransferase beta subunit K00673 - 2.3.1.109 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 456.0
HFD2_k127_6332933_13 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 432.0
HFD2_k127_6332933_14 Transposase IS200 like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 426.0
HFD2_k127_6332933_15 metalloendopeptidase activity K08602 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009505 431.0
HFD2_k127_6332933_16 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 417.0
HFD2_k127_6332933_17 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006994 409.0
HFD2_k127_6332933_18 protein conserved in bacteria K11893 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008951 413.0
HFD2_k127_6332933_19 Responsible for synthesis of pseudouridine from uracil K06179,K06180 - 5.4.99.23,5.4.99.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004732 360.0
HFD2_k127_6332933_2 COG0542 ATPases with chaperone activity, ATP-binding subunit K11907 - - 2.945e-281 896.0
HFD2_k127_6332933_20 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004465 366.0
HFD2_k127_6332933_21 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ K11910 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 368.0
HFD2_k127_6332933_22 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 359.0
HFD2_k127_6332933_23 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 327.0
HFD2_k127_6332933_24 Beta propeller domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 336.0
HFD2_k127_6332933_27 adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000002284 272.0
HFD2_k127_6332933_28 Pfam:T6SS_VasB K11895 - - 0.000000000000000000000000000000000000000000000000000000000000000000001554 269.0
HFD2_k127_6332933_29 Type VI secretion system protein DotU K11892 - - 0.000000000000000000000000000000000000000000000000000000000000000005745 231.0
HFD2_k127_6332933_3 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 7.506e-276 860.0
HFD2_k127_6332933_30 Type VI secretion system, VipA, VC_A0107 or Hcp2 K11901 - - 0.00000000000000000000000000000000000000000000000000000000000000001441 227.0
HFD2_k127_6332933_31 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000008522 211.0
HFD2_k127_6332933_32 Forkhead associated domain K11894,K11913 - - 0.000000000000000000000000000000000000000000000000000000001125 218.0
HFD2_k127_6332933_33 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000002486 204.0
HFD2_k127_6332933_34 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000000000000000000003987 182.0
HFD2_k127_6332933_35 CoA binding domain K06929 - - 0.0000000000000000000000000000000000000000000000003201 188.0
HFD2_k127_6332933_36 Uncharacterized protein conserved in bacteria (DUF2094) K11890 - - 0.000000000000000000000000000000000000000000000005721 190.0
HFD2_k127_6332933_37 - - - - 0.000000000000000000000000000000000000003411 168.0
HFD2_k127_6332933_38 Thioesterase superfamily - - - 0.0000000000000000000000000000000000004726 147.0
HFD2_k127_6332933_39 metallopeptidase activity - - - 0.00000000000000000000000000000000005183 149.0
HFD2_k127_6332933_4 peptidase K01415,K07386 - 3.4.24.71 2.509e-248 787.0
HFD2_k127_6332933_40 protein conserved in bacteria K11905 - - 0.0000000000000000000000000000000001337 137.0
HFD2_k127_6332933_41 PFAM Chorismate mutase of the AroH class K06208 - 5.4.99.5 0.0000000000000000000000000000000004233 134.0
HFD2_k127_6332933_42 cheY-homologous receiver domain - - - 0.0000000000000000000000003117 109.0
HFD2_k127_6332933_43 Regulatory protein, FmdB family - - - 0.0000000000000000000000004049 106.0
HFD2_k127_6332933_44 Type VI secretion system effector, Hcp K11903 - - 0.000000000000000000002117 100.0
HFD2_k127_6332933_45 PFAM Histidine triad (HIT) protein K02503 - - 0.00000000000000000006071 94.0
HFD2_k127_6332933_46 energy transducer activity K03832 - - 0.0000000000000000001172 106.0
HFD2_k127_6332933_49 Type VI secretion K11906 - - 0.00000000002833 71.0
HFD2_k127_6332933_5 protein conserved in bacteria K11900 - - 4.76e-246 767.0
HFD2_k127_6332933_50 HIT domain K02503 - - 0.00000119 62.0
HFD2_k127_6332933_6 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 1.124e-203 641.0
HFD2_k127_6332933_7 ERAP1-like C-terminal domain - - - 3.535e-202 661.0
HFD2_k127_6332933_8 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 5.081e-196 626.0
HFD2_k127_6332933_9 protein conserved in bacteria K11896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 627.0
HFD2_k127_6353298_0 PFAM AMP-dependent synthetase and ligase - - - 0.0 1960.0
HFD2_k127_6353298_1 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1160.0
HFD2_k127_6353298_10 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001484 289.0
HFD2_k127_6353298_11 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000116 213.0
HFD2_k127_6353298_12 TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000007626 207.0
HFD2_k127_6353298_13 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000009195 194.0
HFD2_k127_6353298_14 adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000716 167.0
HFD2_k127_6353298_15 positive regulation of macromolecule biosynthetic process K03973 - - 0.0000000000000000000000000000000008315 132.0
HFD2_k127_6353298_17 PFAM Amino acid-binding ACT - - - 0.000000000000000000000000000000002776 141.0
HFD2_k127_6353298_2 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 2.422e-218 685.0
HFD2_k127_6353298_3 Belongs to the alpha-IPM synthase homocitrate synthase family K01655 - 2.3.3.14 9.639e-201 631.0
HFD2_k127_6353298_4 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005142 606.0
HFD2_k127_6353298_5 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 462.0
HFD2_k127_6353298_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005218 354.0
HFD2_k127_6353298_7 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007425 348.0
HFD2_k127_6353298_8 Serine Threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005858 339.0
HFD2_k127_6353298_9 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 306.0
HFD2_k127_636117_0 choline dehydrogenase activity - - - 1.26e-267 831.0
HFD2_k127_636117_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 1.125e-236 738.0
HFD2_k127_636117_2 lipopolysaccharide transport K22110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005124 465.0
HFD2_k127_636117_3 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 297.0
HFD2_k127_636117_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006598 295.0
HFD2_k127_636117_6 - - - - 0.0000000000000000000000000000000000000000825 158.0
HFD2_k127_636117_7 Protein of unknown function, DUF417 - - - 0.00000000000000000000000000000000000001884 165.0
HFD2_k127_636117_8 Transmembrane anti-sigma factor - - - 0.00000000000000000000000000000006092 128.0
HFD2_k127_636117_9 Transmembrane anti-sigma factor - - - 0.000000000000000000002641 96.0
HFD2_k127_6398862_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 1.651e-248 798.0
HFD2_k127_6398862_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 4.063e-216 679.0
HFD2_k127_6398862_10 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003876 338.0
HFD2_k127_6398862_11 cAMP phosphodiesterases class-II K01120 - 3.1.4.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 333.0
HFD2_k127_6398862_12 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K07106 - 4.2.1.126 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 313.0
HFD2_k127_6398862_13 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005096 340.0
HFD2_k127_6398862_14 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 322.0
HFD2_k127_6398862_15 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 301.0
HFD2_k127_6398862_16 cyclic nucleotide-binding K10914 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002965 246.0
HFD2_k127_6398862_17 lipoprotein transporter activity K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000001778 252.0
HFD2_k127_6398862_18 TonB C terminal K03832 - - 0.000000000000000000000000000000000000000000000000000000001265 216.0
HFD2_k127_6398862_2 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 1.213e-196 617.0
HFD2_k127_6398862_20 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000000000000002865 207.0
HFD2_k127_6398862_21 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000008404 174.0
HFD2_k127_6398862_22 translation initiation factor activity - - - 0.000000000000000000000000000000000000002955 163.0
HFD2_k127_6398862_23 TfoX N-terminal domain K07343 - - 0.0000000000000000000000000000007087 142.0
HFD2_k127_6398862_24 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000000000000001541 119.0
HFD2_k127_6398862_25 MacB-like periplasmic core domain - - - 0.00000000000000000000002603 110.0
HFD2_k127_6398862_26 - K07275 - - 0.000000000000002799 84.0
HFD2_k127_6398862_27 - - - - 0.000000009209 69.0
HFD2_k127_6398862_3 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488 GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009156,GO:0009161,GO:0009163,GO:0009164,GO:0009165,GO:0009167,GO:0009168,GO:0009987,GO:0015949,GO:0015950,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0032261,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0043173,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 569.0
HFD2_k127_6398862_4 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009016 552.0
HFD2_k127_6398862_5 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009045 517.0
HFD2_k127_6398862_6 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006545 471.0
HFD2_k127_6398862_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 483.0
HFD2_k127_6398862_8 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004023 444.0
HFD2_k127_6398862_9 COG1233 Phytoene dehydrogenase and related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000583 415.0
HFD2_k127_6403999_0 Glycosyltransferase like family 2 K20444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 640.0
HFD2_k127_6403999_1 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 384.0
HFD2_k127_6403999_2 Glycosyl transferase K20444 - - 0.00000000000000000000006388 109.0
HFD2_k127_6461071_0 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000574 398.0
HFD2_k127_6461071_1 Penicillin amidase K01434 - 3.5.1.11 0.00000000000000000000004381 113.0
HFD2_k127_6470178_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 3.629e-220 706.0
HFD2_k127_6470178_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 442.0
HFD2_k127_6470178_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 406.0
HFD2_k127_6470178_3 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 306.0
HFD2_k127_6470178_4 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000001476 230.0
HFD2_k127_6470178_5 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000000000000000004141 179.0
HFD2_k127_6470178_6 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000003701 117.0
HFD2_k127_6470178_7 Histidine biosynthesis bifunctional protein HisIE K11755 GO:0000105,GO:0003674,GO:0003824,GO:0004635,GO:0004636,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.6.1.31 0.00000002731 64.0
HFD2_k127_6598767_0 ABC-type multidrug transport system ATPase component K01990 - - 0.0000000002122 66.0
HFD2_k127_6598767_1 cAMP biosynthetic process - - - 0.0000008165 60.0
HFD2_k127_6631542_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 3.227e-236 752.0
HFD2_k127_6631542_1 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009646 594.0
HFD2_k127_6631542_2 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003594 468.0
HFD2_k127_6700913_0 Mut7-C ubiquitin K09122 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 293.0
HFD2_k127_6700913_1 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000000000000000000000000000000000000000000005887 204.0
HFD2_k127_6700913_2 IMP dehydrogenase activity - - - 0.000000000000000000000000000000000000000000002189 168.0
HFD2_k127_6700913_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000002856 165.0
HFD2_k127_6700913_4 Required for optimal acid stress protection. Exhibits a chaperone-like activity only at low pH by suppressing non- specifically the aggregation of denaturated periplasmic proteins K19777 - - 0.00001567 53.0
HFD2_k127_6700913_5 motor activity K10357 - - 0.0001622 48.0
HFD2_k127_6761584_0 FAD linked oxidase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 343.0
HFD2_k127_6792335_0 CobW/HypB/UreG, nucleotide-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000124 252.0
HFD2_k127_6792335_1 Belongs to the carbamate kinase family K00926 - 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000007926 235.0
HFD2_k127_6792335_2 cystathionine gamma-synthase activity K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000003639 224.0
HFD2_k127_6837854_0 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 1.947e-321 996.0
HFD2_k127_6837854_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 571.0
HFD2_k127_6837854_10 - - - - 0.00000000000000000000000000000000000000000000000002991 183.0
HFD2_k127_6837854_11 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000002795 157.0
HFD2_k127_6837854_12 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.00000000009036 62.0
HFD2_k127_6837854_2 Belongs to the SEDS family K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 502.0
HFD2_k127_6837854_3 N-succinyltransferase beta subunit K00673 - 2.3.1.109 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 470.0
HFD2_k127_6837854_4 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 429.0
HFD2_k127_6837854_5 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 333.0
HFD2_k127_6837854_6 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 306.0
HFD2_k127_6837854_8 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000004141 213.0
HFD2_k127_6837854_9 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.000000000000000000000000000000000000000000000000000000000005678 227.0
HFD2_k127_6947405_0 TIGRFAM Methylglyoxal synthase K01734 - 4.2.3.3 0.0000000000000000000000000000000000000000000000000000000000003955 213.0
HFD2_k127_6947405_1 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE - - - 0.000000000000000000000000000000000000000000000000000000001518 210.0
HFD2_k127_6947405_2 Domain of unknown function (DUF4337) - - - 0.00000000000000000000000000000000000000000000000000001714 195.0
HFD2_k127_6947405_3 Belongs to the arginase family K01479,K12255 - 3.5.3.7,3.5.3.8 0.00000000000000000000000000000000000000000000000000611 186.0
HFD2_k127_6947405_4 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000000000000000000000001894 166.0
HFD2_k127_6947405_5 cyclic nucleotide-binding - - - 0.000000000000000000000000000000006906 133.0
HFD2_k127_6947405_6 Protein of unknown function (DUF2470) K07226 - - 0.0000000000000000000000000000001797 128.0
HFD2_k127_6963204_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 3.428e-285 948.0
HFD2_k127_6963204_1 lysine biosynthetic process via aminoadipic acid - - - 2.64e-224 721.0
HFD2_k127_6963204_10 Biopolymer transport protein ExbD TolR K03559 - - 0.0000000000000000000000000000000000000000000004526 169.0
HFD2_k127_6963204_2 Domain of unknown function (DUF814) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004184 578.0
HFD2_k127_6963204_3 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003945 549.0
HFD2_k127_6963204_4 PFAM Multi antimicrobial extrusion protein MatE K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 541.0
HFD2_k127_6963204_5 Surface antigen K07278 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005601 554.0
HFD2_k127_6963204_6 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005881 501.0
HFD2_k127_6963204_7 Belongs to the helicase family. UvrD subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009566 415.0
HFD2_k127_6963204_8 Protein of unknown function DUF45 K07043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000887 281.0
HFD2_k127_6963204_9 MotA TolQ ExbB proton channel K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001566 259.0
HFD2_k127_6964411_0 Oligoendopeptidase f - - - 5.435e-276 863.0
HFD2_k127_6964411_1 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000004966 172.0
HFD2_k127_6964411_2 FCD K05799 - - 0.00000000000000000000000005007 121.0
HFD2_k127_7023519_0 RNA polymerase recycling family C-terminal K03580 - - 0.0 1059.0
HFD2_k127_7023519_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 1.053e-244 770.0
HFD2_k127_7023519_10 PFAM peptidase M20 K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003151 485.0
HFD2_k127_7023519_11 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005512 405.0
HFD2_k127_7023519_13 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 376.0
HFD2_k127_7023519_14 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 366.0
HFD2_k127_7023519_15 Enoyl-CoA hydratase/isomerase K11264 - 4.1.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 323.0
HFD2_k127_7023519_16 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 313.0
HFD2_k127_7023519_17 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 304.0
HFD2_k127_7023519_18 Phenazine biosynthesis-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 335.0
HFD2_k127_7023519_19 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001383 281.0
HFD2_k127_7023519_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 4.459e-230 743.0
HFD2_k127_7023519_21 PAS sensor protein - - - 0.00000000000000000000000000000000000000000002231 185.0
HFD2_k127_7023519_22 PFAM Hemerythrin HHE cation binding domain K07216 - - 0.000000000000000000000000000000000001973 144.0
HFD2_k127_7023519_24 twin-arginine translocation pathway signal protein - - - 0.00000008402 65.0
HFD2_k127_7023519_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 1.111e-212 676.0
HFD2_k127_7023519_4 protein kinase activity - - - 2.35e-212 702.0
HFD2_k127_7023519_5 Histidine kinase - - - 2.447e-199 636.0
HFD2_k127_7023519_6 Belongs to the peptidase M16 family K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004914 608.0
HFD2_k127_7023519_7 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 545.0
HFD2_k127_7023519_8 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 507.0
HFD2_k127_7023519_9 Periplasmic binding protein domain K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 478.0
HFD2_k127_7026513_0 PFAM response regulator receiver K07713 - - 4.745e-209 697.0
HFD2_k127_7026513_1 HAMP domain K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 534.0
HFD2_k127_7026513_10 metallopeptidase activity K06974 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009693 268.0
HFD2_k127_7026513_12 Glycine cleavage H-protein - - - 0.00000000000000000000000000000000000000000000000000000000000000002656 233.0
HFD2_k127_7026513_13 Peptidase family M54 K06974 - - 0.0000000000000000000000000000000000000000000000000000001036 199.0
HFD2_k127_7026513_15 Glycine cleavage H-protein - - - 0.00000000000000000000000000000000000000001273 163.0
HFD2_k127_7026513_16 Redoxin K03564 - 1.11.1.15 0.0000000000000000000000000000003208 124.0
HFD2_k127_7026513_17 Redoxin K03564 - 1.11.1.15 0.00000000000000005929 81.0
HFD2_k127_7026513_2 Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 483.0
HFD2_k127_7026513_3 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 474.0
HFD2_k127_7026513_4 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 469.0
HFD2_k127_7026513_5 Belongs to the N(4) N(6)-methyltransferase family K00571 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005155 476.0
HFD2_k127_7026513_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003857 370.0
HFD2_k127_7026513_7 4Fe-4S dicluster domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 324.0
HFD2_k127_7026513_8 CarD-like/TRCF domain K07736 GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0040007,GO:0042594,GO:0044419,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 320.0
HFD2_k127_7026513_9 Belongs to the GcvT family K06980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001046 274.0
HFD2_k127_7027047_0 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000008357 235.0
HFD2_k127_7027047_1 Integrase - - - 0.00000000000000000000000000000004016 129.0
HFD2_k127_7027047_2 Cupin domain - - - 0.00000000000000000000000001275 116.0
HFD2_k127_7029269_0 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 441.0
HFD2_k127_7029269_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015,K15893 - 1.1.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004463 392.0
HFD2_k127_7029269_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002877 327.0
HFD2_k127_7029269_3 PFAM PHP domain protein K01104 - 3.1.3.48 0.00000000000000000000000000000000000000000000000000000000000006532 222.0
HFD2_k127_7029269_4 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.0000000000000000000000000000000000000000000000000366 184.0
HFD2_k127_7029269_6 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000000000005537 81.0
HFD2_k127_7076298_0 TIGRFAM channel protein, hemolysin III family K11068 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002483 271.0
HFD2_k127_7076298_1 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.000000000000000000009805 97.0
HFD2_k127_7076298_2 Belongs to the RtcB family K14415 - 6.5.1.3 0.000000000001773 67.0
HFD2_k127_7076298_3 Fructose-1,6-bisphosphatase K01622 - 3.1.3.11,4.1.2.13 0.000006504 51.0
HFD2_k127_7115907_0 Patatin-like phospholipase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004241 520.0
HFD2_k127_7115907_1 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000004145 184.0
HFD2_k127_7161641_0 Belongs to the glycosyl hydrolase 57 family - - - 4.857e-310 964.0
HFD2_k127_7161641_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 1.752e-204 648.0
HFD2_k127_7161641_10 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000001826 235.0
HFD2_k127_7161641_11 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000695 218.0
HFD2_k127_7161641_12 Binds together with S18 to 16S ribosomal RNA K01754,K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048027,GO:0070181,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 4.3.1.19 0.000000000000000000000000000000000000000000000000000000005565 203.0
HFD2_k127_7161641_14 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000155 169.0
HFD2_k127_7161641_15 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000001116 152.0
HFD2_k127_7161641_2 TIGRFAM galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004075 556.0
HFD2_k127_7161641_3 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 515.0
HFD2_k127_7161641_4 of the major facilitator superfamily K08151 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 491.0
HFD2_k127_7161641_5 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 402.0
HFD2_k127_7161641_6 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009835 342.0
HFD2_k127_7161641_7 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000001585 268.0
HFD2_k127_7161641_8 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000001252 263.0
HFD2_k127_7161641_9 Zincin-like metallopeptidase K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000001642 268.0
HFD2_k127_7161683_0 Cytochrome C assembly protein - - - 1.243e-199 629.0
HFD2_k127_7161683_1 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 336.0
HFD2_k127_7161683_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000004718 193.0
HFD2_k127_7161683_3 response regulator K02282 - - 0.0000000000000000002572 96.0
HFD2_k127_7183425_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1381.0
HFD2_k127_7183425_1 Histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006743 269.0
HFD2_k127_7183425_2 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.00000000000000000000002032 111.0
HFD2_k127_7183425_3 Sulfatase K01138 - - 0.0000000000002313 83.0
HFD2_k127_7214377_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 7.002e-214 680.0
HFD2_k127_7214377_1 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 346.0
HFD2_k127_7214377_2 ADP-ribosylation factor family K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 343.0
HFD2_k127_7214377_3 Roadblock/LC7 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007861 292.0
HFD2_k127_7265083_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1145.0
HFD2_k127_7265083_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0 1055.0
HFD2_k127_7265083_10 Phosphoserine phosphatase K15781,K21830 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944 2.3.1.51,3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004166 406.0
HFD2_k127_7265083_11 TatD family K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 371.0
HFD2_k127_7265083_12 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 317.0
HFD2_k127_7265083_13 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000744 286.0
HFD2_k127_7265083_15 TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000001174 240.0
HFD2_k127_7265083_17 PFAM DivIVA family protein K04074 - - 0.00000000000000000000000000000000000000000000000000001082 203.0
HFD2_k127_7265083_18 Helix-turn-helix domain - - - 0.000000000000000000000000000007229 122.0
HFD2_k127_7265083_19 zinc ion binding K06204 - - 0.0000000000000000009723 101.0
HFD2_k127_7265083_2 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 7.217e-300 952.0
HFD2_k127_7265083_20 Domain of unknown function (DUF3391) - - - 0.0000000000009851 81.0
HFD2_k127_7265083_21 lyase activity - - - 0.00000001082 68.0
HFD2_k127_7265083_3 response regulator K02481,K07713 - - 3.944e-245 764.0
HFD2_k127_7265083_4 Nucleic acid binding OB-fold tRNA helicase-type K03698 - - 1.556e-198 631.0
HFD2_k127_7265083_5 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007245 575.0
HFD2_k127_7265083_6 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003393 526.0
HFD2_k127_7265083_7 DNA polymerase III, delta' K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 520.0
HFD2_k127_7265083_8 Histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005671 469.0
HFD2_k127_7265083_9 DNA polymerase III K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 422.0
HFD2_k127_7320817_0 membrane organization K03641 - - 0.0 1305.0
HFD2_k127_7320817_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0 1064.0
HFD2_k127_7320817_10 Peptidase, M61 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005339 512.0
HFD2_k127_7320817_11 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012,K16180 - 2.8.1.6,5.4.99.58 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 481.0
HFD2_k127_7320817_12 Threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 441.0
HFD2_k127_7320817_13 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 443.0
HFD2_k127_7320817_14 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000401 442.0
HFD2_k127_7320817_15 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 408.0
HFD2_k127_7320817_16 ABC transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 408.0
HFD2_k127_7320817_17 ADP-ribosylation factor family K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 368.0
HFD2_k127_7320817_18 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006118 366.0
HFD2_k127_7320817_19 DnaJ molecular chaperone homology domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003516 363.0
HFD2_k127_7320817_2 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 5.032e-292 907.0
HFD2_k127_7320817_20 peptidase M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004847 321.0
HFD2_k127_7320817_21 protein trimerization - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 328.0
HFD2_k127_7320817_22 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005257 296.0
HFD2_k127_7320817_23 uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 322.0
HFD2_k127_7320817_24 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 317.0
HFD2_k127_7320817_25 Alpha/beta hydrolase family K03928 - 3.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 290.0
HFD2_k127_7320817_26 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004757 313.0
HFD2_k127_7320817_27 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005667 293.0
HFD2_k127_7320817_28 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000004871 238.0
HFD2_k127_7320817_29 - - - - 0.000000000000000000000000000000000000000000000000000000000000003381 228.0
HFD2_k127_7320817_3 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 1.68e-236 739.0
HFD2_k127_7320817_30 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000155 219.0
HFD2_k127_7320817_32 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.00000000000000000000000000000000000000000000000003011 198.0
HFD2_k127_7320817_33 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000003725 181.0
HFD2_k127_7320817_34 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000000558 165.0
HFD2_k127_7320817_35 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000001239 163.0
HFD2_k127_7320817_36 Protein of unknown function (DUF3467) - - - 0.000000000000000000000000000000000000000007821 161.0
HFD2_k127_7320817_37 - - - - 0.00000000000000000000000000000000000000003346 159.0
HFD2_k127_7320817_38 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.000000000000000000000000000000000002472 140.0
HFD2_k127_7320817_4 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 2.731e-226 709.0
HFD2_k127_7320817_40 Roadblock/LC7 domain - - - 0.00000000000000000000000000001239 117.0
HFD2_k127_7320817_41 3-demethylubiquinone-9 3-O-methyltransferase activity K06219 - - 0.000000000000000000000000004259 122.0
HFD2_k127_7320817_42 photosystem II stabilization K00703,K02237,K02238 - 2.4.1.21 0.0000000000000000002623 96.0
HFD2_k127_7320817_43 Radical SAM - - - 0.000000000000000000688 102.0
HFD2_k127_7320817_44 Dodecin K09165 - - 0.0000000000000000009878 100.0
HFD2_k127_7320817_46 Amidohydrolase - - - 0.0000000000006844 79.0
HFD2_k127_7320817_48 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.000000000005652 76.0
HFD2_k127_7320817_49 Cytochrome c - - - 0.00000003504 59.0
HFD2_k127_7320817_5 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 2.299e-205 654.0
HFD2_k127_7320817_6 Glycosyl transferase, family 2 - - - 2.221e-201 636.0
HFD2_k127_7320817_7 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 604.0
HFD2_k127_7320817_8 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 584.0
HFD2_k127_7320817_9 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004761 530.0
HFD2_k127_7351625_0 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.0 1212.0
HFD2_k127_7351625_1 Carboxyl transferase domain K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 3.349e-298 920.0
HFD2_k127_7351625_10 phospho-2-dehydro-3-deoxyheptonate aldolase K03856,K04516 - 2.5.1.54,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 531.0
HFD2_k127_7351625_11 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 516.0
HFD2_k127_7351625_12 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006628 509.0
HFD2_k127_7351625_13 Ferredoxin-fold anticodon binding domain K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007856 490.0
HFD2_k127_7351625_14 chromosome segregation K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 469.0
HFD2_k127_7351625_15 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 452.0
HFD2_k127_7351625_16 nuclear chromosome segregation K02557,K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 446.0
HFD2_k127_7351625_17 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 436.0
HFD2_k127_7351625_18 PFAM Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006985 394.0
HFD2_k127_7351625_19 Transposase IS4 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 345.0
HFD2_k127_7351625_2 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 2.705e-287 892.0
HFD2_k127_7351625_20 Methylates ribosomal protein L11 K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007345 336.0
HFD2_k127_7351625_21 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 342.0
HFD2_k127_7351625_22 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000742 327.0
HFD2_k127_7351625_23 Peptidase C26 K01658,K01664 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005339 325.0
HFD2_k127_7351625_24 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003131 323.0
HFD2_k127_7351625_25 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 320.0
HFD2_k127_7351625_26 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006122 282.0
HFD2_k127_7351625_28 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000000002464 239.0
HFD2_k127_7351625_29 PGAP1-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000002547 241.0
HFD2_k127_7351625_3 Tetratricopeptide repeat - - - 4.203e-284 930.0
HFD2_k127_7351625_30 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.000000000000000000000000000000000000000000000000000000000000005545 218.0
HFD2_k127_7351625_31 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000194 229.0
HFD2_k127_7351625_32 Biotin-requiring enzyme - - - 0.000000000000000000000000000000000000000000000000000000003404 223.0
HFD2_k127_7351625_34 PFAM Cold-shock protein, DNA-binding K03704 - - 0.000000000000000000000000000000001205 131.0
HFD2_k127_7351625_35 RDD family - - - 0.00000000000000000006052 99.0
HFD2_k127_7351625_4 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 7.073e-273 846.0
HFD2_k127_7351625_5 Biotin carboxylase C-terminal domain K01941,K01961 - 6.3.4.14,6.3.4.6,6.4.1.2 1.078e-254 799.0
HFD2_k127_7351625_6 Peptidase family M28 - - - 5.086e-246 775.0
HFD2_k127_7351625_7 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 5.068e-239 747.0
HFD2_k127_7351625_8 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 2.775e-211 667.0
HFD2_k127_7351625_9 phospho-2-dehydro-3-deoxyheptonate aldolase K03856,K04516 - 2.5.1.54,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009768 581.0
HFD2_k127_7382723_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 7.443e-263 835.0
HFD2_k127_7382723_1 Belongs to the aconitase IPM isomerase family K01682 - 4.2.1.3,4.2.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000002425 269.0
HFD2_k127_7382723_2 ADP-glyceromanno-heptose 6-epimerase activity K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000003158 219.0
HFD2_k127_7382723_3 glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.0000000000000000000000000000000000000008578 154.0
HFD2_k127_7479821_0 Glycosyl transferase family 2 K20534 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 325.0
HFD2_k127_7479821_1 Glycosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000001218 210.0
HFD2_k127_7479821_2 NAD(P)H-binding - - - 0.000000000000000000000123 98.0
HFD2_k127_7608759_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 467.0
HFD2_k127_7608759_1 cAMP biosynthetic process - - - 0.0004732 49.0
HFD2_k127_7670008_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 0.0 1082.0
HFD2_k127_7670008_1 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006387 546.0
HFD2_k127_7670008_2 exonuclease activity K16899 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004465 558.0
HFD2_k127_7670008_3 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009104 565.0
HFD2_k127_7670008_4 Protein of unknown function (DUF507) K09804 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 319.0
HFD2_k127_7670008_5 thiolester hydrolase activity K06889 - - 0.0000000000000000000000000000000000000000003961 182.0
HFD2_k127_7896952_0 Sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007948 365.0
HFD2_k127_7896952_1 GIY-YIG catalytic domain K07461 - - 0.000004399 49.0
HFD2_k127_7927598_0 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007469 609.0
HFD2_k127_7927598_1 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000002286 181.0
HFD2_k127_7927598_2 - K07018 - - 0.0000000000003181 83.0
HFD2_k127_8022133_0 spore germination - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001981 255.0
HFD2_k127_8022133_1 malic enzyme K00027,K22212 - 1.1.1.38,4.1.1.101 0.000001013 52.0
HFD2_k127_80290_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 2.695e-200 635.0
HFD2_k127_80290_1 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000001848 177.0
HFD2_k127_8033189_0 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004369 258.0
HFD2_k127_8033189_1 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000000000000000000005119 233.0
HFD2_k127_8033189_2 PUA-like domain K00958 - 2.7.7.4 0.0000000000000000000000000001161 115.0
HFD2_k127_8063788_0 Histidine kinase K13924 - 2.1.1.80,3.1.1.61 1.104e-291 947.0
HFD2_k127_8063788_1 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 2.102e-215 700.0
HFD2_k127_8063788_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 348.0
HFD2_k127_8063788_11 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 334.0
HFD2_k127_8063788_12 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000353 299.0
HFD2_k127_8063788_13 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001773 276.0
HFD2_k127_8063788_14 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000001958 269.0
HFD2_k127_8063788_15 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000001822 259.0
HFD2_k127_8063788_16 DJ-1/PfpI family K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000000000002474 254.0
HFD2_k127_8063788_17 Bacterial regulatory proteins, tetR family K16137 - - 0.0000000000000000000000000000000000000000000000000000000000000000001 258.0
HFD2_k127_8063788_18 Rhomboid family K07059 - - 0.0000000000000000000000000000000000000000000000000000000000000851 223.0
HFD2_k127_8063788_19 Doxx family K15977 - - 0.0000000000000000000000000000000000000000000000000000004428 197.0
HFD2_k127_8063788_2 Serine Threonine protein kinase K12132 - 2.7.11.1 2.857e-207 684.0
HFD2_k127_8063788_20 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.000000000000000000000000000000000000000000000000002475 206.0
HFD2_k127_8063788_21 Domain of unknown function (DUF4405) - - - 0.000000000000000000000000000000000000000001475 180.0
HFD2_k127_8063788_22 DNA-templated transcription, initiation K03088,K11333 - 1.3.7.14,1.3.7.15 0.000000000000000000000000000000000000000006187 173.0
HFD2_k127_8063788_23 - - - - 0.0000000000000000000000000000000000000111 152.0
HFD2_k127_8063788_24 cheY-homologous receiver domain - - - 0.0000000000000000000000000000001045 130.0
HFD2_k127_8063788_25 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 0.0000000000000000000000000000002428 123.0
HFD2_k127_8063788_26 PFAM peptidase M52 hydrogen uptake protein K03605 - - 0.000000000000000000000000000275 128.0
HFD2_k127_8063788_28 Protein of unknown function (DUF1326) - - - 0.00000000000000000000000006828 114.0
HFD2_k127_8063788_29 Pyridoxamine 5'-phosphate oxidase K09979 - - 0.0000000000000000000000003461 113.0
HFD2_k127_8063788_3 PFAM Xanthine uracil vitamin C permease K06901 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006688 613.0
HFD2_k127_8063788_30 PFAM Cyclic nucleotide-binding K10914,K21563 - - 0.000000000000000000000001742 112.0
HFD2_k127_8063788_31 protein import - - - 0.00000000000000000000006232 111.0
HFD2_k127_8063788_34 ABC-2 family transporter protein K01992 - - 0.0000000000007236 71.0
HFD2_k127_8063788_35 permease K07243 - - 0.00000000002995 74.0
HFD2_k127_8063788_36 - - - - 0.0000000001272 72.0
HFD2_k127_8063788_37 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000002422 70.0
HFD2_k127_8063788_38 Metallo-peptidase family M12B Reprolysin-like - - - 0.00000001686 64.0
HFD2_k127_8063788_39 Cupin domain - - - 0.0009424 46.0
HFD2_k127_8063788_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 549.0
HFD2_k127_8063788_40 PilZ domain - - - 0.0009532 50.0
HFD2_k127_8063788_5 FIST N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 525.0
HFD2_k127_8063788_6 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282,K18008 - 1.12.2.1,1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 479.0
HFD2_k127_8063788_7 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003575 448.0
HFD2_k127_8063788_8 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004773 434.0
HFD2_k127_8063788_9 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 382.0
HFD2_k127_8072616_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 377.0
HFD2_k127_8072616_1 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 345.0
HFD2_k127_8072616_2 PFAM Zn-finger in ubiquitin-hydrolases and other protein - - - 0.000000000000000000000000000000000000000000008836 170.0
HFD2_k127_8072616_3 peptidase - - - 0.0000000000000000000000000000000009343 147.0
HFD2_k127_8072616_4 Domain of unknown function (DU1801) - - - 0.000000000000000000000003819 109.0
HFD2_k127_8072616_5 Uncharacterized conserved protein (DUF2277) - - - 0.00000000000000000000006217 115.0
HFD2_k127_8072616_6 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000004256 73.0
HFD2_k127_8072616_7 aminopeptidase activity - - - 0.0001528 53.0
HFD2_k127_8074637_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 1.352e-313 1001.0
HFD2_k127_8074637_1 Amino acid permease - - - 2.038e-292 916.0
HFD2_k127_8074637_10 - - - - 0.00000000000000000003256 97.0
HFD2_k127_8074637_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 7.251e-261 814.0
HFD2_k127_8074637_3 Bacterial regulatory protein, Fis family K11384 - - 7.176e-200 632.0
HFD2_k127_8074637_4 HAMP domain K11383 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 589.0
HFD2_k127_8074637_5 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 492.0
HFD2_k127_8074637_6 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007086 392.0
HFD2_k127_8074637_7 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000004409 251.0
HFD2_k127_8074637_8 beta-lactamase domain protein K06897 - 2.5.1.105 0.00000000000000000000000000000000000000000000000000000007966 199.0
HFD2_k127_8116076_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1064.0
HFD2_k127_8116076_1 lysine 2,3-aminomutase K01843 - 5.4.3.2 3.272e-221 690.0
HFD2_k127_8116076_10 Stage II sporulation D domain protein K06381 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002556 293.0
HFD2_k127_8116076_11 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002363 282.0
HFD2_k127_8116076_13 LUD domain K00782 - - 0.0000000000000000000000000000000000000000000005596 182.0
HFD2_k127_8116076_14 Thiamine-binding protein - - - 0.000000000000000000000000000000000000000005376 159.0
HFD2_k127_8116076_15 endoribonuclease L-PSP K01482 - 3.5.3.18 0.00000000000000000000000000000002563 130.0
HFD2_k127_8116076_16 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.0000000000000000000000000001743 129.0
HFD2_k127_8116076_2 cluster binding protein K18929 - - 4.062e-206 662.0
HFD2_k127_8116076_3 4Fe-4S dicluster domain K18930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008855 610.0
HFD2_k127_8116076_4 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005975 563.0
HFD2_k127_8116076_5 lysine 2,3-aminomutase K01843 - 5.4.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004143 554.0
HFD2_k127_8116076_6 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 471.0
HFD2_k127_8116076_7 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 334.0
HFD2_k127_8116076_8 PFAM Cysteine-rich domain K18928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 345.0
HFD2_k127_8116076_9 histone H2A K63-linked ubiquitination - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004056 323.0
HFD2_k127_8124388_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 7.124e-243 771.0
HFD2_k127_8124388_1 FtsZ-dependent cytokinesis - - - 0.0000000000000000000000000000000000000001316 158.0
HFD2_k127_8132876_0 asparagine synthase K01953 - 6.3.5.4 0.00000000000000009846 94.0
HFD2_k127_8169715_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0 1192.0
HFD2_k127_8169715_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 1.809e-283 888.0
HFD2_k127_8169715_10 - K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007712 483.0
HFD2_k127_8169715_11 AAA domain (dynein-related subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004456 442.0
HFD2_k127_8169715_12 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003264 413.0
HFD2_k127_8169715_13 VWA domain containing CoxE-like protein K07161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 422.0
HFD2_k127_8169715_14 Protein of unknown function (DUF475) K09799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000068 399.0
HFD2_k127_8169715_15 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005488 388.0
HFD2_k127_8169715_16 PFAM Tripartite ATP-independent periplasmic transporter DctQ component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 326.0
HFD2_k127_8169715_17 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000653 322.0
HFD2_k127_8169715_18 Belongs to the hyi family K01816 - 5.3.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 312.0
HFD2_k127_8169715_19 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 299.0
HFD2_k127_8169715_2 Cytochrome C assembly protein - - - 1.463e-265 833.0
HFD2_k127_8169715_20 Membrane transport protein K07088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009745 290.0
HFD2_k127_8169715_21 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000004482 271.0
HFD2_k127_8169715_22 [2Fe-2S] binding domain K03518,K13483 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000551 242.0
HFD2_k127_8169715_23 XdhC Rossmann domain K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000003846 234.0
HFD2_k127_8169715_24 Nudix hydrolase K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000005219 231.0
HFD2_k127_8169715_25 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase K03772,K03773 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000007548 226.0
HFD2_k127_8169715_26 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000000000000000000000000008545 217.0
HFD2_k127_8169715_29 XdhC and CoxI family - - - 0.00000000000000000000000000000000000003386 147.0
HFD2_k127_8169715_3 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 4.726e-243 778.0
HFD2_k127_8169715_30 Carbon monoxide dehydrogenase subunit G (CoxG) - - - 0.00000000000000000000000000000000001626 145.0
HFD2_k127_8169715_31 Sigma-54 interaction domain K07713,K07714,K07715 - - 0.0000000000000000000000000000001114 136.0
HFD2_k127_8169715_32 AntiSigma factor - - - 0.0000000000000000000000000007346 129.0
HFD2_k127_8169715_33 COG0822 NifU homolog involved in Fe-S cluster formation - - - 0.0000000000000000000000001436 120.0
HFD2_k127_8169715_34 Putative bacterial sensory transduction regulator - - - 0.00000000000000000006071 96.0
HFD2_k127_8169715_35 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase K01802,K03772,K03773 - 5.2.1.8 0.00000000000000237 78.0
HFD2_k127_8169715_4 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 1.731e-239 761.0
HFD2_k127_8169715_5 Di-haem cytochrome c peroxidase - - - 5.304e-229 763.0
HFD2_k127_8169715_6 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.235e-228 725.0
HFD2_k127_8169715_7 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 589.0
HFD2_k127_8169715_8 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 568.0
HFD2_k127_8169715_9 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 531.0
HFD2_k127_8200098_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1521.0
HFD2_k127_8200098_1 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 7.715e-292 904.0
HFD2_k127_8200098_10 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005529 355.0
HFD2_k127_8200098_11 Domain present in PSD-95, Dlg, and ZO-1/2. K02452 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000362 363.0
HFD2_k127_8200098_12 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000655 341.0
HFD2_k127_8200098_13 ABC transporter K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008924 345.0
HFD2_k127_8200098_14 Type II secretion system (T2SS), protein K K02460 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004324 315.0
HFD2_k127_8200098_15 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002038 269.0
HFD2_k127_8200098_16 HAD-hyrolase-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000002306 254.0
HFD2_k127_8200098_17 Type II secretion system (T2SS), protein J K02459 - - 0.0000000000000000000000000000000000000000000000000000000000001757 235.0
HFD2_k127_8200098_18 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000004831 221.0
HFD2_k127_8200098_19 - - - - 0.00000000000000000000000000000000000000000000000000000001143 204.0
HFD2_k127_8200098_2 Type II and III secretion system protein K02453 - - 1.553e-277 896.0
HFD2_k127_8200098_20 general secretion pathway protein K02456,K02457,K02650 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.00000000000000000000000000000000000000000000000000000005028 208.0
HFD2_k127_8200098_21 Prokaryotic N-terminal methylation motif K02458 - - 0.00000000000000000000000000000000000000000000000005848 191.0
HFD2_k127_8200098_22 Type II secretion system (T2SS), protein M K02462 - - 0.000000000000000000000000000000000000000000000002297 197.0
HFD2_k127_8200098_23 Binds the 23S rRNA K02909 - - 0.00000000000000000000000000000000000000000002867 164.0
HFD2_k127_8200098_24 general secretion pathway protein G K02456 - - 0.000000000000000000000000000000000000008714 149.0
HFD2_k127_8200098_25 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000000000000000000000001929 138.0
HFD2_k127_8200098_3 Glycosyl transferase family 21 - - - 8.697e-234 734.0
HFD2_k127_8200098_4 Type IV pilus assembly protein PilM; K02461 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007849 603.0
HFD2_k127_8200098_5 General secretion pathway protein F K02455,K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006286 578.0
HFD2_k127_8200098_6 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003867 525.0
HFD2_k127_8200098_7 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 491.0
HFD2_k127_8200098_8 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 464.0
HFD2_k127_8200098_9 Peptidase family M23 K21471 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 396.0
HFD2_k127_8218129_0 Elongation factor G, domain IV K02355 - - 0.0 1070.0
HFD2_k127_8218129_1 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 1.626e-255 800.0
HFD2_k127_8218129_2 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 519.0
HFD2_k127_8218129_3 Membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 464.0
HFD2_k127_8218129_4 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 398.0
HFD2_k127_8218129_5 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001403 269.0
HFD2_k127_8218129_6 UPF0056 inner membrane protein K05595 - - 0.000000000000000000000000000000000000000000000000000002841 210.0
HFD2_k127_8218129_7 Thioesterase K18700 - 3.1.2.29 0.00000000000000000000000000000000000000000000000005414 193.0
HFD2_k127_8218129_8 Histidine kinase K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000001449 186.0
HFD2_k127_8218129_9 DNA-binding transcription factor activity K03892,K22298 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0008150,GO:0010035,GO:0010038,GO:0010045,GO:0032025,GO:0042221,GO:0050896,GO:0097159,GO:1901363 - 0.000000000001516 68.0
HFD2_k127_8249309_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0 1201.0
HFD2_k127_8249309_1 type IV pilus secretin PilQ K02666 - - 2.554e-288 907.0
HFD2_k127_8249309_10 Pilus assembly protein, PilP K02665 - - 0.0000000000000000000000000000000000000000000000000000000003759 205.0
HFD2_k127_8249309_11 TonB C terminal K03646,K03832 - - 0.000000000000000000000000000000000000000000000000000000001775 215.0
HFD2_k127_8249309_12 Biopolymer transport protein ExbD/TolR K03560 - - 0.00000000000000000000000000000000000000000000000005016 193.0
HFD2_k127_8249309_13 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000000000000005045 181.0
HFD2_k127_8249309_14 Roadblock/LC7 domain - - - 0.00000000000000000000000000000000000000000000007315 175.0
HFD2_k127_8249309_2 Surface antigen - - - 1.286e-263 844.0
HFD2_k127_8249309_3 Tetratricopeptide repeats - - - 5.556e-243 777.0
HFD2_k127_8249309_4 Biotin carboxylase K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 5.557e-237 742.0
HFD2_k127_8249309_5 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 505.0
HFD2_k127_8249309_6 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009814 497.0
HFD2_k127_8249309_7 MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006958 360.0
HFD2_k127_8249309_8 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 350.0
HFD2_k127_8249309_9 Ppx GppA K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 367.0
HFD2_k127_8279302_0 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 334.0
HFD2_k127_8279302_1 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000006851 226.0
HFD2_k127_8279302_2 cytochrome - - - 0.0000000000000000000000000000000000001869 159.0
HFD2_k127_8279302_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000006262 163.0
HFD2_k127_8279302_4 Domain of unknown function (DUF1924) - - - 0.000000000000000000000000000000005728 145.0
HFD2_k127_8279302_5 PFAM Di-haem cytochrome c - - - 0.000000000000000000000000000002049 127.0
HFD2_k127_8279302_6 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000008924 124.0
HFD2_k127_8310819_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008431 355.0
HFD2_k127_8310819_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000433 334.0
HFD2_k127_8310819_2 Sigma-54 interaction domain K07713,K07714 - - 0.00000000000000000000000000001503 137.0
HFD2_k127_8329145_0 regulation of single-species biofilm formation K13573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007158 462.0
HFD2_k127_8329145_1 Flavin containing amine oxidoreductase K01854 - 5.4.99.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 369.0
HFD2_k127_8329145_2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042,K18121 - 1.1.1.31,1.1.1.60,1.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 357.0
HFD2_k127_8329145_3 WYL domain K13572 - - 0.00000000000000000000000000000000000000000000000000000000000000000002733 253.0
HFD2_k127_8329145_4 Protein of unknown function (DUF1054) - - - 0.00000000000000000000000000000000000000000000000000000727 200.0
HFD2_k127_8329145_5 Response regulator, receiver K03413 - - 0.000000000000000000000000000000000000001522 168.0
HFD2_k127_8358263_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0 1141.0
HFD2_k127_8358263_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 6.352e-282 891.0
HFD2_k127_8358263_10 COG0436 Aspartate tyrosine aromatic aminotransferase K14287 - 2.6.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005684 535.0
HFD2_k127_8358263_11 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458,K14660 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003313 480.0
HFD2_k127_8358263_12 Periplasmic binding protein K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006298 486.0
HFD2_k127_8358263_13 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005111 439.0
HFD2_k127_8358263_14 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005758 440.0
HFD2_k127_8358263_15 PFAM Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 442.0
HFD2_k127_8358263_16 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007491 420.0
HFD2_k127_8358263_17 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 424.0
HFD2_k127_8358263_18 PFAM Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 424.0
HFD2_k127_8358263_19 4Fe-4S single cluster domain of Ferredoxin I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003299 404.0
HFD2_k127_8358263_2 Class III cytochrome C family - - - 2.231e-249 798.0
HFD2_k127_8358263_20 TIGRFAM cytochrome C family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007346 424.0
HFD2_k127_8358263_21 PPIC-type PPIASE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000885 405.0
HFD2_k127_8358263_22 PFAM Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 398.0
HFD2_k127_8358263_23 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 402.0
HFD2_k127_8358263_24 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005528 392.0
HFD2_k127_8358263_25 6 heme-binding sites - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 378.0
HFD2_k127_8358263_26 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009428 381.0
HFD2_k127_8358263_27 PFAM MscS Mechanosensitive ion channel K16052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 393.0
HFD2_k127_8358263_28 PFAM ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009316 361.0
HFD2_k127_8358263_29 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 350.0
HFD2_k127_8358263_3 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 1.358e-242 779.0
HFD2_k127_8358263_30 branched-chain amino acid K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008275 344.0
HFD2_k127_8358263_31 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 355.0
HFD2_k127_8358263_32 Cytochrome c oxidase subunit K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 345.0
HFD2_k127_8358263_33 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 346.0
HFD2_k127_8358263_34 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003179 358.0
HFD2_k127_8358263_35 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006585 329.0
HFD2_k127_8358263_36 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 327.0
HFD2_k127_8358263_37 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 306.0
HFD2_k127_8358263_38 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 298.0
HFD2_k127_8358263_39 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 299.0
HFD2_k127_8358263_4 Aldehyde dehydrogenase family K00129 - 1.2.1.5 3.364e-208 662.0
HFD2_k127_8358263_40 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006022 271.0
HFD2_k127_8358263_41 PFAM glycosyl transferase family 25 K07270 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002154 266.0
HFD2_k127_8358263_42 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002604 264.0
HFD2_k127_8358263_43 COG0463 Glycosyltransferases involved in cell wall biogenesis K13002 - - 0.000000000000000000000000000000000000000000000000000000000000000000004737 243.0
HFD2_k127_8358263_44 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000002646 235.0
HFD2_k127_8358263_45 Glycosyl transferase family 2 K00786 - - 0.000000000000000000000000000000000000000000000000000000000000000107 232.0
HFD2_k127_8358263_46 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000004871 229.0
HFD2_k127_8358263_47 protein SCO1 SenC K07152 - - 0.000000000000000000000000000000000000000000000000000000000000005351 232.0
HFD2_k127_8358263_48 Putative bacterial lipoprotein (DUF799) - - - 0.000000000000000000000000000000000000000000000000000000000000008037 221.0
HFD2_k127_8358263_49 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000000000000000000000000000008967 213.0
HFD2_k127_8358263_5 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 583.0
HFD2_k127_8358263_51 Cytochrome c oxidase, subunit III K02276,K02299 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000006114 215.0
HFD2_k127_8358263_52 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000000003681 200.0
HFD2_k127_8358263_55 NmrA-like family - - - 0.000000000000000000000000000000000000000000000006311 187.0
HFD2_k127_8358263_56 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000000000000000007377 176.0
HFD2_k127_8358263_57 Protein of unknown function (DUF420) K08976 - - 0.00000000000000000000000000000000000000000001595 165.0
HFD2_k127_8358263_58 this gene contains a nucleotide ambiguity which may be the result of a sequencing error - - - 0.000000000000000000000000000000000001161 162.0
HFD2_k127_8358263_59 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000001636 160.0
HFD2_k127_8358263_6 chaperone-mediated protein folding K21007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005294 556.0
HFD2_k127_8358263_60 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000009873 156.0
HFD2_k127_8358263_61 Hemerythrin HHE cation binding domain K07216 - - 0.0000000000000000000000000000000003197 141.0
HFD2_k127_8358263_62 - K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.000000000000000000000000000000001566 135.0
HFD2_k127_8358263_63 heme a metabolic process K02257,K02259 - 2.5.1.141 0.0000000000000000000000000000001661 135.0
HFD2_k127_8358263_65 Protein of unknown function (FYDLN_acid) - - - 0.000000000000001195 89.0
HFD2_k127_8358263_66 EamA-like transporter family - - - 0.0000000000002058 75.0
HFD2_k127_8358263_68 methyltransferase - - - 0.00000004594 66.0
HFD2_k127_8358263_69 Domain of unknown function (DUF4136) - - - 0.0000000601 65.0
HFD2_k127_8358263_7 TIGRFAM cytochrome C family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 539.0
HFD2_k127_8358263_71 Uncharacterized conserved protein (DUF2304) K09153 - - 0.00002505 56.0
HFD2_k127_8358263_72 PFAM transposase IS3 IS911 family protein K07497 - - 0.0006094 51.0
HFD2_k127_8358263_8 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 516.0
HFD2_k127_8358263_9 Bacterial membrane protein, YfhO - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009217 559.0
HFD2_k127_8410857_0 Endothelin-converting enzyme K01415,K07386 - 3.4.24.71 9.884e-228 721.0
HFD2_k127_8410857_1 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000001088 56.0
HFD2_k127_8445316_0 COG2015, Alkyl sulfatase and related hydrolases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003674 370.0
HFD2_k127_8445316_1 Transcriptional Regulator, AraC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009799 253.0
HFD2_k127_8445316_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000009242 158.0
HFD2_k127_847851_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1951.0
HFD2_k127_847851_1 pyruvate phosphate dikinase K01006 - 2.7.9.1 0.0 1404.0
HFD2_k127_847851_10 PFAM Silent information regulator protein Sir2 K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 389.0
HFD2_k127_847851_11 Dihydrodipicolinate reductase, N-terminus K21672 - 1.4.1.12,1.4.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006703 379.0
HFD2_k127_847851_12 Dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 308.0
HFD2_k127_847851_13 Cys/Met metabolism PLP-dependent enzyme K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 310.0
HFD2_k127_847851_14 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001241 269.0
HFD2_k127_847851_15 PFAM MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001346 259.0
HFD2_k127_847851_16 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000835 231.0
HFD2_k127_847851_17 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000003794 230.0
HFD2_k127_847851_18 Staphylococcal nuclease homologue - - - 0.0000000000000000000000000000000000000000000000000000000000003238 221.0
HFD2_k127_847851_19 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000000000000000000004745 216.0
HFD2_k127_847851_2 Bacterial regulatory protein, Fis family K07713 - - 8.404e-210 665.0
HFD2_k127_847851_20 TRAP transporter T-component - - - 0.0000000000000000000000000000000000000000000000000000000000006861 219.0
HFD2_k127_847851_21 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000000000000000000000000000000000000001459 206.0
HFD2_k127_847851_22 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000000000000000000000001852 230.0
HFD2_k127_847851_23 Single Cache domain 2 - - - 0.00000000000000000000000000000000000000000000000000000004921 218.0
HFD2_k127_847851_24 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.000000000000000000000000000000000000000000000000001485 195.0
HFD2_k127_847851_25 ApaG domain K06195 - - 0.000000000000000000000000000000000000000000000000003599 183.0
HFD2_k127_847851_26 PFAM amino acid-binding ACT domain protein - - - 0.0000000000000000000000000000000000000000000000899 174.0
HFD2_k127_847851_27 Biopolymer transport protein K03559 - - 0.0000000000000000000000000000000000000000000008581 180.0
HFD2_k127_847851_28 Belongs to the sulfur carrier protein TusA family K04085 - - 0.0000000000000000000000003175 118.0
HFD2_k127_847851_3 Thiamine biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 577.0
HFD2_k127_847851_31 phosphorelay sensor kinase activity - - - 0.000000000000000005836 88.0
HFD2_k127_847851_32 SdpI/YhfL protein family - - - 0.00000000001876 74.0
HFD2_k127_847851_34 Putative zinc-finger - - - 0.0001348 55.0
HFD2_k127_847851_4 HAMP domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 567.0
HFD2_k127_847851_5 Protein-disulfide isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007415 507.0
HFD2_k127_847851_6 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004695 442.0
HFD2_k127_847851_7 Cell division protein FtsI penicillin-binding protein 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 442.0
HFD2_k127_847851_8 Serine Threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000866 457.0
HFD2_k127_847851_9 Heat shock protein DnaJ domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 434.0
HFD2_k127_8592787_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 4.736e-292 904.0
HFD2_k127_8592787_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 1.083e-232 742.0
HFD2_k127_8592787_10 - - - - 0.000000002758 69.0
HFD2_k127_8592787_2 histidyl-tRNA synthetase K01892 - 6.1.1.21 1.434e-214 673.0
HFD2_k127_8592787_3 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 8.356e-198 635.0
HFD2_k127_8592787_4 Belongs to the phosphatidylserine decarboxylase family K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003667 411.0
HFD2_k127_8592787_5 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 378.0
HFD2_k127_8592787_6 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 365.0
HFD2_k127_8592787_7 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000000000000000000000000000000000302 192.0
HFD2_k127_8592787_8 protein family UPF0079, ATPase K06925 - - 0.0000000000000000000000000000000000000000000000004032 199.0
HFD2_k127_8592787_9 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000000005174 149.0
HFD2_k127_882335_0 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 481.0
HFD2_k127_882335_1 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 398.0
HFD2_k127_882335_2 Phosphoserine phosphatase K15781,K21830 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944 2.3.1.51,3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 391.0
HFD2_k127_882335_3 Nucleic acid binding OB-fold tRNA helicase-type K03698 - - 0.0000000000000000000000000000000000000000000000000004141 193.0
HFD2_k127_882335_4 Predicted membrane protein (DUF2214) K08983 - - 0.000000000000000000001435 100.0
HFD2_k127_904870_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 2.505e-284 883.0
HFD2_k127_904870_1 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 2.862e-230 730.0
HFD2_k127_904870_10 MotA/TolQ/ExbB proton channel family K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 325.0
HFD2_k127_904870_11 Transposase IS200 like K07491 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002368 280.0
HFD2_k127_904870_12 Biopolymer transport protein ExbD/TolR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000901 260.0
HFD2_k127_904870_13 Response regulator receiver domain K03413 - - 0.00000000000000000000000000000000000000000000000000000000000000005088 226.0
HFD2_k127_904870_14 chemotaxis K03410 GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896,GO:0050918 - 0.0000000000000000000000000000000000000000000000000000000000001115 240.0
HFD2_k127_904870_15 Biopolymer transport protein ExbD/TolR - - - 0.000000000000000000000000000000000000000000000000000009487 193.0
HFD2_k127_904870_16 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000001047 190.0
HFD2_k127_904870_17 chemotaxis K02659,K03408 - - 0.000000000000000000000000000000000000001872 153.0
HFD2_k127_904870_2 Histidine kinase - - - 5.939e-201 647.0
HFD2_k127_904870_3 PFAM ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 610.0
HFD2_k127_904870_4 histidine kinase HAMP region domain protein K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004427 582.0
HFD2_k127_904870_6 Belongs to the LarC family K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 464.0
HFD2_k127_904870_7 AIR carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 364.0
HFD2_k127_904870_8 Small GTP-binding protein K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004819 346.0
HFD2_k127_904870_9 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 332.0
HFD2_k127_937357_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 8.04e-240 759.0
HFD2_k127_937357_1 Capsule assembly protein Wzi - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 350.0
HFD2_k127_937357_3 ATP-dependent protease La (LON) substrate-binding domain K01338,K07157 - 3.4.21.53 0.000000001481 60.0
HFD2_k127_942740_0 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 392.0
HFD2_k127_942740_1 endonuclease activity K07451 - - 0.000000000000000000000000000000000000000000000000000703 188.0
HFD2_k127_942740_2 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000004595 121.0
HFD2_k127_94295_0 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004864 294.0
HFD2_k127_94295_1 PFAM Smr protein MutS2 - - - 0.0000000000000000000000000001194 128.0
HFD2_k127_978239_0 repeat protein - - - 0.0 3917.0
HFD2_k127_978239_1 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.0 1110.0
HFD2_k127_978239_10 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 8.6e-199 633.0
HFD2_k127_978239_11 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 4.099e-197 635.0
HFD2_k127_978239_12 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 579.0
HFD2_k127_978239_13 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 554.0
HFD2_k127_978239_14 Histidine kinase K13598 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008777 528.0
HFD2_k127_978239_15 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003114 515.0
HFD2_k127_978239_16 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 485.0
HFD2_k127_978239_17 alcohol dehydrogenase K18012 - 1.4.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004771 481.0
HFD2_k127_978239_18 Forkhead associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 486.0
HFD2_k127_978239_19 aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006937 466.0
HFD2_k127_978239_2 Tetratricopeptide repeat - - - 0.0 1103.0
HFD2_k127_978239_20 Phosphotransferase enzyme family K02204 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003927 426.0
HFD2_k127_978239_21 TPR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 374.0
HFD2_k127_978239_22 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 327.0
HFD2_k127_978239_23 RDD family K18481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 302.0
HFD2_k127_978239_24 protein trimerization - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003592 276.0
HFD2_k127_978239_25 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007136 280.0
HFD2_k127_978239_26 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006902 267.0
HFD2_k127_978239_27 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007303 262.0
HFD2_k127_978239_28 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000005244 216.0
HFD2_k127_978239_29 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000009854 235.0
HFD2_k127_978239_3 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 6.973e-303 968.0
HFD2_k127_978239_30 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K15546 - - 0.0000000000000000000000000000000000000000000000000000000002302 216.0
HFD2_k127_978239_33 dipeptide transport K02035 - - 0.000000000000000000000000000000000000000000000000000001568 219.0
HFD2_k127_978239_36 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000000000000000000000000007666 188.0
HFD2_k127_978239_37 Uncharacterized conserved protein (DUF2203) - - - 0.0000000000000000000000000000000000000000000004115 170.0
HFD2_k127_978239_38 PilZ domain K02676 - - 0.00000000000000000000000000000000000000000001058 171.0
HFD2_k127_978239_39 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.0000000000000000000000000000000000000002918 163.0
HFD2_k127_978239_4 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 3.637e-275 882.0
HFD2_k127_978239_40 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000000000000000000003797 152.0
HFD2_k127_978239_41 Protein of unknown function (DUF2721) - - - 0.00000000000000000000000000000006598 129.0
HFD2_k127_978239_43 - - - - 0.0000000000000000000000000007896 119.0
HFD2_k127_978239_45 Integrase - - - 0.0000000000000000000000002748 109.0
HFD2_k127_978239_49 - - - - 0.000003697 53.0
HFD2_k127_978239_5 Peptidase S46 - - - 8.796e-244 774.0
HFD2_k127_978239_50 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000008527 55.0
HFD2_k127_978239_6 Peptidase, M61 - - - 2.941e-229 723.0
HFD2_k127_978239_7 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 9.859e-227 704.0
HFD2_k127_978239_8 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 9.354e-221 696.0
HFD2_k127_978239_9 FHA domain - - - 1.883e-214 684.0
HFD2_k127_984591_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1441.0
HFD2_k127_984591_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1278.0
HFD2_k127_984591_10 Aminotransferase K01845 - 5.4.3.8 1.672e-199 651.0
HFD2_k127_984591_11 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 609.0
HFD2_k127_984591_12 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 539.0
HFD2_k127_984591_13 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003153 541.0
HFD2_k127_984591_14 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 526.0
HFD2_k127_984591_15 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 522.0
HFD2_k127_984591_16 COG1073 hydrolases of the alpha beta superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000967 555.0
HFD2_k127_984591_17 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 473.0
HFD2_k127_984591_18 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006426 456.0
HFD2_k127_984591_19 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 452.0
HFD2_k127_984591_2 Heat shock 70 kDa protein K04043 - - 0.0 1040.0
HFD2_k127_984591_20 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004654 447.0
HFD2_k127_984591_21 Belongs to the RimK family K05844,K14940 - 6.3.2.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 462.0
HFD2_k127_984591_22 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 409.0
HFD2_k127_984591_23 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 393.0
HFD2_k127_984591_24 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005437 404.0
HFD2_k127_984591_25 NUBPL iron-transfer P-loop NTPase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 385.0
HFD2_k127_984591_26 Belongs to the PdxA family K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 389.0
HFD2_k127_984591_27 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004057 344.0
HFD2_k127_984591_28 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007498 341.0
HFD2_k127_984591_29 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009069 329.0
HFD2_k127_984591_3 4Fe-4S dicluster domain - - - 4.928e-301 953.0
HFD2_k127_984591_30 long-chain fatty acid transporting porin activity K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 299.0
HFD2_k127_984591_31 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 317.0
HFD2_k127_984591_32 SurA N-terminal domain K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000008809 265.0
HFD2_k127_984591_33 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.0000000000000000000000000000000000000000000000000000000000000000000001597 253.0
HFD2_k127_984591_34 photosynthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000002668 243.0
HFD2_k127_984591_35 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000000000000000000000000004691 231.0
HFD2_k127_984591_36 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000002547 230.0
HFD2_k127_984591_37 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000000000000000000000000003281 255.0
HFD2_k127_984591_38 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000001064 227.0
HFD2_k127_984591_39 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000000000000000004346 220.0
HFD2_k127_984591_4 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.793e-289 914.0
HFD2_k127_984591_40 HAD-hyrolase-like - - - 0.000000000000000000000000000000000000000000000000000000000000821 225.0
HFD2_k127_984591_41 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000000000000000000000357 207.0
HFD2_k127_984591_42 ATP synthesis coupled proton transport K02109 - - 0.00000000000000000000000000000000000000000000000000003834 194.0
HFD2_k127_984591_43 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000000000006516 186.0
HFD2_k127_984591_44 R3H domain K06346 - - 0.0000000000000000000000000000000000000000000000000575 201.0
HFD2_k127_984591_46 Peptidase family M54 K06974 - - 0.000000000000000000000000000000000000000000000009975 181.0
HFD2_k127_984591_47 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.0000000000000000000000000000000000000000002721 164.0
HFD2_k127_984591_48 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000000000000000000000000174 128.0
HFD2_k127_984591_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 5.651e-273 856.0
HFD2_k127_984591_51 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000003836 108.0
HFD2_k127_984591_52 ATP hydrolysis coupled proton transport K02110,K02124 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000008058 106.0
HFD2_k127_984591_53 PFAM Phage derived protein Gp49-like (DUF891) - GO:0001666,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0036293,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0045926,GO:0045927,GO:0046483,GO:0048518,GO:0048519,GO:0050789,GO:0050896,GO:0065007,GO:0070482,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 - 0.000000000000000000000004287 107.0
HFD2_k127_984591_54 Protein of unknown function (DUF433) - - - 0.00000000000000000007148 96.0
HFD2_k127_984591_57 Protein of unknown function (DUF2283) - - - 0.00000000000001619 80.0
HFD2_k127_984591_58 DNA integration - - - 0.0000000000003814 83.0
HFD2_k127_984591_59 sequence-specific DNA binding - - - 0.000000000001481 78.0
HFD2_k127_984591_6 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 6.171e-271 846.0
HFD2_k127_984591_60 - - - - 0.000000002783 60.0
HFD2_k127_984591_61 Heavy-metal resistance - - - 0.00000006621 66.0
HFD2_k127_984591_62 - - - - 0.00000111 51.0
HFD2_k127_984591_63 Belongs to the 'phage' integrase family - - - 0.00004809 54.0
HFD2_k127_984591_7 SMART helicase c2 K03722 - 3.6.4.12 3.056e-263 833.0
HFD2_k127_984591_8 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 6.201e-257 833.0
HFD2_k127_984591_9 ABC-type branched-chain amino acid transport K07121 - - 3.934e-206 666.0