logo

Overview

ID MAG01660
Name HFD2_bin.52
Sample SMP0044
Taxonomy
Kingdom Bacteria
Phylum Myxococcota
Class Polyangia
Order Polyangiales
Family Polyangiaceae
Genus Labilithrix
Species
Assembly information
Completeness (%) 51.55
Contamination (%) 0.23
GC content (%) 62.0
N50 (bp) 3,664
Genome size (bp) 7,382,607

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes5134

Gene name Description KEGG GOs EC E-value Score Sequence
HFD2_k127_1002415_0 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005097 491.0
HFD2_k127_1002415_1 DnaJ molecular chaperone homology domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005801 338.0
HFD2_k127_1002415_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000001028 203.0
HFD2_k127_1002415_3 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 0.000000000000000000000000000000000005705 141.0
HFD2_k127_1004173_0 Vault protein inter-alpha-trypsin domain - - - 0.00000000000000000000000000000000000000000000001503 177.0
HFD2_k127_1004173_1 AMP-binding enzyme K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000001607 192.0
HFD2_k127_1004173_2 Uncharacterised conserved protein (DUF2228) - - - 0.00000000000000000000000000006582 135.0
HFD2_k127_1004173_3 DNA ligase OB-like domain K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000003254 83.0
HFD2_k127_1011428_0 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 324.0
HFD2_k127_1011428_1 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000001245 219.0
HFD2_k127_1011428_2 ATP-grasp - - - 0.0000000000000000000000000005342 116.0
HFD2_k127_1019629_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 - 3.4.21.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 414.0
HFD2_k127_1019629_1 thiolester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000002986 213.0
HFD2_k127_1019629_2 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000000000004142 172.0
HFD2_k127_1025606_0 cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000009672 278.0
HFD2_k127_1025606_1 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000000000000000001908 212.0
HFD2_k127_1027586_0 beta-ketoacyl-acyl-carrier-protein synthase III activity K00648 - 2.3.1.180 0.000000000000000000000000000000000001114 144.0
HFD2_k127_103082_0 Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007006 261.0
HFD2_k127_103082_1 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000002596 223.0
HFD2_k127_1038262_0 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 430.0
HFD2_k127_1038262_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005729 383.0
HFD2_k127_1038262_2 - - - - 0.000000000000000000006537 100.0
HFD2_k127_1041262_0 class I DNA-(apurinic or apyrimidinic site) endonuclease activity K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000537 274.0
HFD2_k127_1044528_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009166 489.0
HFD2_k127_1044528_1 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 340.0
HFD2_k127_1044528_2 ABC transporter K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000000000004171 205.0
HFD2_k127_1047558_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 349.0
HFD2_k127_1047558_1 Amidohydrolase family - - - 0.000005945 49.0
HFD2_k127_1047558_2 Belongs to the ompA family - - - 0.0001622 52.0
HFD2_k127_1050030_0 Acetyltransferase (GNAT) domain - GO:0003674,GO:0003824,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 306.0
HFD2_k127_1050030_1 Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003799 283.0
HFD2_k127_1050030_2 Belongs to the bacterial histone-like protein family - - - 0.00000000000000000000000000000000000002145 146.0
HFD2_k127_1050030_3 cellulose binding K01179 - 3.2.1.4 0.0000001955 62.0
HFD2_k127_10503_0 MMPL family K07003 - - 2.237e-250 805.0
HFD2_k127_10503_1 Pfam:DUF2029 - - - 0.0000000000000000000005969 109.0
HFD2_k127_1050837_0 malate quinone oxidoreductase K00116 - 1.1.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000926 258.0
HFD2_k127_1051134_0 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 1.269e-203 644.0
HFD2_k127_1051134_1 Phage shock protein A K03969 GO:0003674,GO:0005488,GO:0005515,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006950,GO:0008150,GO:0008289,GO:0009266,GO:0009271,GO:0009408,GO:0009605,GO:0009607,GO:0009615,GO:0009628,GO:0009889,GO:0009898,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019897,GO:0019898,GO:0031234,GO:0031323,GO:0031326,GO:0042802,GO:0043167,GO:0043168,GO:0043207,GO:0043433,GO:0044092,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0048519,GO:0050789,GO:0050794,GO:0050896,GO:0051090,GO:0051171,GO:0051252,GO:0051704,GO:0051707,GO:0060187,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0098552,GO:0098562,GO:0098586,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000002065 235.0
HFD2_k127_1051442_0 Periplasmic protein TonB links inner and outer membranes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 430.0
HFD2_k127_1052256_1 Type II IV secretion system protein K02283,K03609 - - 0.0000000000844 71.0
HFD2_k127_1052551_0 Protein kinase domain K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008465 570.0
HFD2_k127_1052551_1 Belongs to the amidase family K19176 - 3.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003295 486.0
HFD2_k127_1052551_2 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666,K01897 - 6.2.1.3 0.0000003193 53.0
HFD2_k127_1054358_0 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 485.0
HFD2_k127_1055139_0 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004537 331.0
HFD2_k127_1060322_0 Lactonase, 7-bladed beta-propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005926 257.0
HFD2_k127_1060322_1 - - - - 0.000000000000000000000000000000000000000000000002541 190.0
HFD2_k127_1060322_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000003003 137.0
HFD2_k127_1060474_0 nucleoside 2-deoxyribosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000001033 229.0
HFD2_k127_1060474_1 sporulation resulting in formation of a cellular spore K06381 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - 0.000000000000000000000003642 115.0
HFD2_k127_1060474_2 - - - - 0.00000000000000000004171 93.0
HFD2_k127_1060474_3 membrane - - - 0.00001511 54.0
HFD2_k127_1069872_0 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 431.0
HFD2_k127_1069872_1 - - - - 0.00000000000000000000007083 101.0
HFD2_k127_1069872_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000007557 101.0
HFD2_k127_1076985_0 Thermolysin metallopeptidase, alpha-helical domain K01400 GO:0005575,GO:0005576 3.4.24.28 0.0000000000000000000000000000000000000000000000000000000000000000001121 253.0
HFD2_k127_1076985_1 cellulose binding - - - 0.000000000000000000000000000000000000000001867 170.0
HFD2_k127_1076985_2 Beta-L-arabinofuranosidase, GH127 - - - 0.0000000004738 71.0
HFD2_k127_1078040_0 Signal transduction histidine kinase K13598 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 338.0
HFD2_k127_1078040_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 291.0
HFD2_k127_1078040_2 ABC transporter K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000667 288.0
HFD2_k127_1078040_3 PHB/PHA accumulation regulator DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000001441 185.0
HFD2_k127_1078040_4 Redoxin K02199 - - 0.0000000000000000000000000000000000007475 148.0
HFD2_k127_1078040_5 AntiSigma factor - - - 0.00001138 54.0
HFD2_k127_1078834_0 amino acid activation for nonribosomal peptide biosynthetic process K20952 - - 0.00000000000000000000000000000000000000000000001168 186.0
HFD2_k127_1078834_1 belongs to the thioredoxin family K20543 - - 0.00000000000000000000000008635 118.0
HFD2_k127_1082291_0 PFAM cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 319.0
HFD2_k127_1082291_1 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000138 235.0
HFD2_k127_1082291_2 tRNAPhe (7-(3-amino-3-carboxypropyl)wyosine37-C2)-hydroxylase activity K10277,K20285 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.14.11.27 0.0000000000000000000001191 107.0
HFD2_k127_1082294_0 Carbamoyl-phosphate synthase (glutamine-hydrolyzing) K01955 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009013 368.0
HFD2_k127_1083577_0 Uncharacterized protein conserved in bacteria (DUF2330) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008633 277.0
HFD2_k127_1083577_2 Uncharacterized protein conserved in bacteria (DUF2330) - - - 0.000000000000000005673 93.0
HFD2_k127_1084118_0 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.00000000000000000000000000000000000000000000000000000000008947 220.0
HFD2_k127_1084118_1 PFAM MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000001411 169.0
HFD2_k127_1084118_2 Biopolymer transport protein ExbD/TolR K03560 - - 0.00000000000000000000000000000000000004583 148.0
HFD2_k127_1084118_3 Rhomboid family - - - 0.0000000618 63.0
HFD2_k127_1084118_4 TonB family K03646,K03832 - - 0.000002069 58.0
HFD2_k127_1084118_5 WD-40 repeat - - - 0.00008791 55.0
HFD2_k127_1085647_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 393.0
HFD2_k127_1085647_1 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 305.0
HFD2_k127_1085647_3 PFAM Formylglycine-generating sulfatase enzyme K12132 - 2.7.11.1 0.0000000000000000000001027 104.0
HFD2_k127_1085647_4 - - - - 0.0000000000009374 78.0
HFD2_k127_1088753_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000003225 70.0
HFD2_k127_1098824_0 Type II/IV secretion system protein K02283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009966 584.0
HFD2_k127_1106872_0 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000268 152.0
HFD2_k127_1106872_1 SCP-2 sterol transfer family - - - 0.000000000000000000009099 98.0
HFD2_k127_1106872_3 Cytochrome c - - - 0.0000001733 57.0
HFD2_k127_1106872_4 response regulator - - - 0.00001345 52.0
HFD2_k127_1106950_0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007682 359.0
HFD2_k127_1106950_1 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000003202 204.0
HFD2_k127_1106950_2 response regulator containing a CheY-like receiver domain and a GGDEF domain K02488 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 2.7.7.65 0.00000000000000000000000000000000000000000004706 179.0
HFD2_k127_1106950_3 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01006 - 2.7.9.1 0.00000000000000000000000000000000001554 139.0
HFD2_k127_1106950_6 OmpA family - - - 0.000000000002494 78.0
HFD2_k127_111415_0 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.000000000000000000000000000000000000057 153.0
HFD2_k127_111415_1 Tellurite resistance protein TerB K05801 - - 0.00000003693 64.0
HFD2_k127_111415_2 PFAM Vitamin K-dependent gamma-carboxylase - - - 0.00001523 56.0
HFD2_k127_1115033_0 CheR methyltransferase, all-alpha domain K00575,K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 342.0
HFD2_k127_1115033_1 CheB methylesterase K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000003538 264.0
HFD2_k127_1122966_0 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005656 374.0
HFD2_k127_1122966_1 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000003021 197.0
HFD2_k127_1122966_2 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000000001878 178.0
HFD2_k127_1123814_0 AAA domain (dynein-related subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 308.0
HFD2_k127_1123814_1 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000000000000000000000000003616 228.0
HFD2_k127_1123814_2 COG1664 Integral membrane protein CcmA involved in cell shape determination - - - 0.00006608 51.0
HFD2_k127_1128901_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 GO:0000287,GO:0003674,GO:0003824,GO:0004799,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009157,GO:0009162,GO:0009165,GO:0009176,GO:0009177,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009314,GO:0009394,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046073,GO:0046385,GO:0046483,GO:0046872,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005496 398.0
HFD2_k127_1128901_1 Periplasmic binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 339.0
HFD2_k127_1128901_2 Transcription factor K18850 - 1.14.11.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000667 288.0
HFD2_k127_1128901_3 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.0000000000000000000000000000000000001084 147.0
HFD2_k127_1128901_4 Beta-L-arabinofuranosidase, GH127 - - - 0.00000004199 65.0
HFD2_k127_1129188_0 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 368.0
HFD2_k127_1129188_1 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000005389 275.0
HFD2_k127_1129188_2 Protein of unknown function (DUF1109) - - - 0.00000000000000000000000000000000000000001385 156.0
HFD2_k127_1135536_0 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008242 348.0
HFD2_k127_1135536_1 General secretory system II, protein E domain protein K02454 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 308.0
HFD2_k127_1135536_2 General secretory system II, protein E domain protein K02454 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001022 257.0
HFD2_k127_1135536_3 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000004322 108.0
HFD2_k127_1135536_4 Domain of unknown function (DUF4185) - - - 0.00000000001054 78.0
HFD2_k127_1138126_0 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000004979 191.0
HFD2_k127_1138126_1 Biopolymer transport protein ExbD/TolR - - - 0.00000000000000001766 91.0
HFD2_k127_1150715_0 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009318 317.0
HFD2_k127_1150715_1 MlaD protein K06192 - - 0.0000000000000000000000000000000000000000000000000000000000000009221 230.0
HFD2_k127_1150715_2 Permease MlaE K02066 - - 0.000000000000000000000000000002326 122.0
HFD2_k127_1152822_0 Anticodon-binding domain of tRNA K01873 - 6.1.1.9 0.0 1135.0
HFD2_k127_1152822_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006297 347.0
HFD2_k127_1160285_0 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 330.0
HFD2_k127_1160893_0 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000004511 275.0
HFD2_k127_1161576_0 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 505.0
HFD2_k127_1161576_1 YHYH protein - - - 0.000000000000000000000000004258 113.0
HFD2_k127_1161576_2 Fungalysin/Thermolysin Propeptide Motif K01400,K01401,K19351 GO:0005575,GO:0005576 3.4.24.28,3.4.24.29 0.0009807 51.0
HFD2_k127_1166563_0 FIST C domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000663 258.0
HFD2_k127_1166563_1 DnaJ C terminal domain K03686,K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000306 222.0
HFD2_k127_1166563_2 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000000000000000000000000000000000003723 202.0
HFD2_k127_1166563_3 Histidine kinase K13040 - 2.7.13.3 0.000000001408 69.0
HFD2_k127_1170287_0 adventurous gliding protein T - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004224 309.0
HFD2_k127_1170287_1 COG0526 Thiol-disulfide isomerase and thioredoxins K03671 - - 0.00000000000000000000000000000000000000003731 154.0
HFD2_k127_1170287_2 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000006522 103.0
HFD2_k127_1170287_3 - - - - 0.00000000000000004459 90.0
HFD2_k127_117140_0 Putative modulator of DNA gyrase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004553 311.0
HFD2_k127_117140_1 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003828 281.0
HFD2_k127_117140_2 Putative modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001174 263.0
HFD2_k127_117140_3 Putative modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000002628 214.0
HFD2_k127_1172206_0 protein kinase activity - - - 0.00000000000000000000000000008205 128.0
HFD2_k127_1172206_1 cell envelope organization K05807,K08309 - - 0.0000000000000000000000007848 117.0
HFD2_k127_1191047_0 ATP:ADP antiporter activity K01932,K03301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005957 374.0
HFD2_k127_1191047_1 phosphatidate phosphatase activity K19302 - 3.6.1.27 0.000000000000000000000000000000000009753 147.0
HFD2_k127_1191047_2 Belongs to the ompA family - - - 0.000000012 60.0
HFD2_k127_1198234_0 Cation transporter/ATPase, N-terminus K01537,K01539 - 3.6.3.8,3.6.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005983 333.0
HFD2_k127_1198234_1 PFAM SMP-30 Gluconolaconase - - - 0.00002509 54.0
HFD2_k127_1201836_0 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000001393 193.0
HFD2_k127_1201836_1 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000007298 145.0
HFD2_k127_1201836_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000008491 139.0
HFD2_k127_1201836_3 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00008228 53.0
HFD2_k127_1201836_4 Thioredoxin-like - - - 0.0003987 44.0
HFD2_k127_1201836_5 Potassium channel K21867 GO:0001101,GO:0003674,GO:0005215,GO:0005216,GO:0005244,GO:0005249,GO:0005261,GO:0005267,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006950,GO:0008150,GO:0008324,GO:0009266,GO:0009409,GO:0009414,GO:0009415,GO:0009628,GO:0009719,GO:0009725,GO:0009737,GO:0009753,GO:0009987,GO:0010033,GO:0010035,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015271,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022803,GO:0022832,GO:0022836,GO:0022838,GO:0022839,GO:0022843,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0033993,GO:0034220,GO:0042221,GO:0042391,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051234,GO:0055065,GO:0055067,GO:0055075,GO:0055080,GO:0055085,GO:0065007,GO:0065008,GO:0071804,GO:0071805,GO:0071944,GO:0097305,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:1901700 - 0.0005338 52.0
HFD2_k127_1202230_0 aminopeptidase N - - - 0.0000000000000000000000000000000000000000000000000000000000000007909 225.0
HFD2_k127_1202230_1 TPM domain K06872 - - 0.000000000000000000000000000000002802 143.0
HFD2_k127_1202769_0 Sulfate transporter antisigma-factor antagonist STAS K03321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 518.0
HFD2_k127_1209153_0 KaiC K08482 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006476 526.0
HFD2_k127_1209153_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003114 384.0
HFD2_k127_1209153_2 AAA ATPase domain - - - 0.00000000000000000000000002172 111.0
HFD2_k127_1209153_3 - - - - 0.0002771 51.0
HFD2_k127_1211351_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000001049 237.0
HFD2_k127_1211351_1 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000000000000008253 197.0
HFD2_k127_1211351_2 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000009274 179.0
HFD2_k127_1213797_0 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000004618 182.0
HFD2_k127_1213797_1 Sigma-54 interaction domain K07713,K07714 - - 0.000000000000000000000000000000009313 134.0
HFD2_k127_1215625_0 belongs to the thioredoxin family K01023,K03671 - 2.8.2.22 0.000000003024 70.0
HFD2_k127_1216364_0 ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004597 287.0
HFD2_k127_1216391_0 Domain of unknown function (DUF4132) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 334.0
HFD2_k127_1218971_0 pilus assembly protein K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004689 433.0
HFD2_k127_1218971_1 Fimbrial assembly protein (PilN) K02663 - - 0.000000000000000000000000000000000000000000007989 169.0
HFD2_k127_1222754_0 PFAM ABC transporter related K01995 - - 0.000000000000001501 79.0
HFD2_k127_1222754_1 Involved in the tonB-independent uptake of proteins - - - 0.0000003322 64.0
HFD2_k127_1223490_0 stress-induced mitochondrial fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005297 292.0
HFD2_k127_1223490_1 transferase hexapeptide K02617,K03321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001617 267.0
HFD2_k127_1223490_2 stress-induced mitochondrial fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009115 265.0
HFD2_k127_1223490_3 phosphatase K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000004694 222.0
HFD2_k127_1231706_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 441.0
HFD2_k127_1231706_1 Zinc-dependent metalloprotease - - - 0.0000000000000000000000000000000000000000000000001697 189.0
HFD2_k127_1233741_0 Acyl-CoA dehydrogenase, C-terminal domain K00249,K11731 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 514.0
HFD2_k127_1235043_0 Peptidase family M50 K06212,K06402 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 344.0
HFD2_k127_1235043_1 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.00000000007948 67.0
HFD2_k127_1235043_2 universal stress protein - - - 0.00001326 55.0
HFD2_k127_1236664_0 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 365.0
HFD2_k127_1236664_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000002906 173.0
HFD2_k127_1244350_0 Tetratricopeptide repeat - - - 1.509e-216 739.0
HFD2_k127_1244350_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000001578 174.0
HFD2_k127_1244418_0 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000002129 235.0
HFD2_k127_1244418_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000004471 214.0
HFD2_k127_1250404_0 Family membership - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005791 312.0
HFD2_k127_1250404_1 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000728 224.0
HFD2_k127_1250404_2 Pfam:Ureidogly_hydro K01483 - 4.3.2.3 0.00000000000000000000000000000000000000000000000005076 188.0
HFD2_k127_1263786_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000001077 109.0
HFD2_k127_1271301_0 response regulator K02481,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003678 464.0
HFD2_k127_1271301_1 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.00000000000000003237 82.0
HFD2_k127_1279244_0 Transcriptional regulator - - - 0.00000000000006218 80.0
HFD2_k127_1280027_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002749 459.0
HFD2_k127_1280027_1 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008054 389.0
HFD2_k127_1280027_2 WGR domain protein - - - 0.0000000000000000000000000005669 117.0
HFD2_k127_1280292_0 - - - - 0.0000000000000000000000000004496 129.0
HFD2_k127_1280292_1 TIGRFAM repeat-companion domain TIGR02996 - - - 0.0000000000000000000004411 110.0
HFD2_k127_1284103_0 interspecies interaction between organisms - - - 0.00000000000000000000000000000000000000005855 162.0
HFD2_k127_1290938_0 Tryptophanyl-tRNA synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009412 345.0
HFD2_k127_1290938_1 Belongs to the N(4) N(6)-methyltransferase family K00571 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000004716 242.0
HFD2_k127_1290938_2 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000002399 94.0
HFD2_k127_1292390_0 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007774 261.0
HFD2_k127_1292390_1 Member of a two-component regulatory system K02484,K07644,K07645,K18143 GO:0003674,GO:0003824,GO:0004672,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0033554,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000004519 235.0
HFD2_k127_129334_0 Bacterial transglutaminase-like N-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003427 383.0
HFD2_k127_129334_1 Circularly permuted ATP-grasp type 2 - - - 0.00000000000000000000000000000000000000000000000000000006765 202.0
HFD2_k127_1293409_0 PFAM von Willebrand factor type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000053 278.0
HFD2_k127_1293409_1 Transcriptional regulator K03717 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001828 280.0
HFD2_k127_1293409_2 Membrane protein, TerC K05794 - - 0.0000000000000000000000000000000000000000000000000000000000002639 227.0
HFD2_k127_1293409_3 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.000000000000000000000000000000000000000001894 166.0
HFD2_k127_1293409_4 cell adhesion involved in biofilm formation - - - 0.00000000001208 74.0
HFD2_k127_1293409_5 - - - - 0.000004603 53.0
HFD2_k127_1298677_0 Protein of unknown function (DUF1385) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000849 354.0
HFD2_k127_1298677_1 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008051 320.0
HFD2_k127_1298677_2 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000000000000003655 188.0
HFD2_k127_1298677_3 negative regulation of translational initiation - - - 0.000000000000000000000000000000000000001655 153.0
HFD2_k127_1298677_4 Binds the 23S rRNA K02909 - - 0.000000000000000000000001594 108.0
HFD2_k127_1298677_5 - - - - 0.00000903 57.0
HFD2_k127_1301658_0 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000001865 201.0
HFD2_k127_1301658_1 amine dehydrogenase activity - - - 0.0000000000000001819 94.0
HFD2_k127_1301658_2 Kazal type serine protease inhibitors - - - 0.0000000001388 70.0
HFD2_k127_1301658_3 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000225 57.0
HFD2_k127_1303784_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 422.0
HFD2_k127_1303784_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.000000000000000000000000000000000000000000000000005729 196.0
HFD2_k127_1303784_2 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000001071 61.0
HFD2_k127_1305032_0 - - - - 0.000000000000000000000000000000000001306 152.0
HFD2_k127_1305032_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.000000000000000004665 89.0
HFD2_k127_1305225_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000007177 245.0
HFD2_k127_130525_0 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000001436 185.0
HFD2_k127_130525_1 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K03561,K12287 - - 0.000000000000000000000005364 112.0
HFD2_k127_130525_2 Trypsin-like serine protease - - - 0.0000000000000002259 91.0
HFD2_k127_1306613_0 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 400.0
HFD2_k127_1306613_1 - - - - 0.00000000000000000000000000000000000000000047 176.0
HFD2_k127_1311671_0 PRMT5 arginine-N-methyltransferase K11434 - 2.1.1.319 0.0000000000000000000000000000000000000000000000000000000000000001124 232.0
HFD2_k127_1311671_1 ABC transporter CydDC cysteine exporter (CydDC-E) family permease ATP-binding protein CydD K16013,K16014 - - 0.00000000000000000000000007439 123.0
HFD2_k127_1311671_2 COGs COG1215 Glycosyltransferase probably involved in cell wall biogenesis - - - 0.0000000000001532 76.0
HFD2_k127_1323026_0 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000001085 233.0
HFD2_k127_1323026_2 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00002073 48.0
HFD2_k127_1328238_0 regulation of DNA-templated transcription, elongation - - - 0.0000000000000000000000000000000000000000000000000000000000000002115 244.0
HFD2_k127_1328238_1 protein kinase activity - - - 0.0000000000000000000000000000000000000000000006745 171.0
HFD2_k127_1334534_0 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K03229 - - 0.0000000000000000000000000000000000000003715 160.0
HFD2_k127_1334534_1 protein kinase activity - - - 0.00000000000000002487 88.0
HFD2_k127_1334534_2 SCO1/SenC K07152 - - 0.00000000000003874 81.0
HFD2_k127_1340301_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000024 182.0
HFD2_k127_1340301_1 domain, Protein - - - 0.00000000000004923 83.0
HFD2_k127_1340301_2 PFAM Mo-dependent nitrogenase - - - 0.000005756 52.0
HFD2_k127_1340301_3 - - - - 0.00001856 56.0
HFD2_k127_1340597_1 TIGRFAM cytochrome C family protein - - - 0.00000000000000002081 87.0
HFD2_k127_1346594_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004144 416.0
HFD2_k127_1346594_1 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07659 - - 0.0000000000000000003933 94.0
HFD2_k127_1349624_0 Family membership K12132 - 2.7.11.1 0.000000000000000000000000000000000008425 155.0
HFD2_k127_1349790_0 Voltage gated chloride channel K03281 - - 0.000000000000000000000000000000000000000000000000000000000004299 214.0
HFD2_k127_1349790_1 serine-type endopeptidase activity - - - 0.000000000000000008282 93.0
HFD2_k127_1352959_0 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000001049 230.0
HFD2_k127_1352959_1 membrane K08978 - - 0.0000000000000397 75.0
HFD2_k127_1354197_0 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000382 256.0
HFD2_k127_1354197_1 amine dehydrogenase activity - - - 0.000000000000000009133 89.0
HFD2_k127_135624_1 - - - - 0.000000000002038 68.0
HFD2_k127_13624_0 PFAM cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004072 345.0
HFD2_k127_13624_1 Carboxylesterase family - - - 0.00000002243 66.0
HFD2_k127_1369500_0 GMC oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005467 463.0
HFD2_k127_1369500_1 Domain of unknown function (DUF4139) - - - 0.00000000000000000000000000000000000000000000007971 179.0
HFD2_k127_1372634_0 RNA-DNA hybrid ribonuclease activity K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004545 313.0
HFD2_k127_1372634_1 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000000000000000000000000000000000000000002376 205.0
HFD2_k127_1372634_2 Galactose oxidase, central domain - - - 0.0000000000004144 78.0
HFD2_k127_1375107_0 Cytochrome C biogenesis protein transmembrane region K04084 - 1.8.1.8 0.00000000000000131 83.0
HFD2_k127_1375107_1 - - - - 0.0000002628 55.0
HFD2_k127_1379329_1 - - - - 0.000000000000000000001222 105.0
HFD2_k127_1389506_0 phosphorelay signal transduction system K01768,K10941,K11894 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 374.0
HFD2_k127_1389506_1 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007147 310.0
HFD2_k127_1389506_2 serine threonine protein kinase - - - 0.00001049 56.0
HFD2_k127_1401548_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 327.0
HFD2_k127_1401548_1 Protease prsW family - - - 0.0000000000000000000000000000000000000001153 155.0
HFD2_k127_1401548_2 Binds directly to 16S ribosomal RNA K02968 - - 0.0000001494 56.0
HFD2_k127_1411383_0 Belongs to the peptidase S8 family K14645 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 511.0
HFD2_k127_1411383_1 Cupin - - - 0.000000006864 63.0
HFD2_k127_1421248_0 NAD(P)H-binding - - - 0.0000000000000000000000000000000000002123 146.0
HFD2_k127_1421912_0 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000007172 222.0
HFD2_k127_1436627_1 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.00000000000000000000000002898 114.0
HFD2_k127_1436627_2 integral membrane protein - - - 0.0000000008232 67.0
HFD2_k127_1438079_0 PAP2 superfamily - - - 0.0000000006087 70.0
HFD2_k127_1439260_0 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 347.0
HFD2_k127_1439260_1 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.000000000000000000000000000006567 138.0
HFD2_k127_1439260_2 Serine Threonine protein kinase K12132 - 2.7.11.1 0.0000000000001803 84.0
HFD2_k127_1439260_3 peptidyl-tyrosine sulfation - - - 0.00000000001379 72.0
HFD2_k127_1441651_0 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002013 252.0
HFD2_k127_1441651_1 Transcription factor zinc-finger K09981 - - 0.0009819 49.0
HFD2_k127_144440_0 PEGA domain - - - 0.00000000000000000000000000000000000002872 156.0
HFD2_k127_144440_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000005703 79.0
HFD2_k127_144440_2 Leishmanolysin family - - - 0.00008761 51.0
HFD2_k127_1447120_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000003114 241.0
HFD2_k127_1447120_1 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000001083 191.0
HFD2_k127_1447120_3 - - - - 0.000009895 55.0
HFD2_k127_1447872_0 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 6.961e-292 923.0
HFD2_k127_1447872_1 Urease, gamma subunit K01430,K14048 - 3.5.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 308.0
HFD2_k127_1447872_2 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03190 - - 0.00000000000000000000009225 105.0
HFD2_k127_1452387_0 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000004513 248.0
HFD2_k127_1452387_1 YCII-related domain - - - 0.0000000000000000000000000000000002192 139.0
HFD2_k127_1452406_0 phosphorelay signal transduction system K01768,K10941,K11894 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003929 423.0
HFD2_k127_1452406_1 Transcriptional regulator - - - 0.0000000000000000000007719 102.0
HFD2_k127_1452450_0 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005546 400.0
HFD2_k127_1452450_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 379.0
HFD2_k127_1452450_2 - - - - 0.00000000000000000000000000000000000003304 156.0
HFD2_k127_1452450_4 Mannosyl oligosaccharide glucosidase - - - 0.0000000000000009478 77.0
HFD2_k127_1452450_5 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000001333 64.0
HFD2_k127_1456607_0 ABC-type transport system involved in lipoprotein release permease component K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008032 412.0
HFD2_k127_1456607_1 Gaf domain - - - 0.000000000000000000000000000000000000000002518 179.0
HFD2_k127_1456607_2 oligosaccharyl transferase activity - - - 0.00002338 53.0
HFD2_k127_1457629_0 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009148 510.0
HFD2_k127_1457629_1 Leucine Rich repeat - - - 0.00008506 49.0
HFD2_k127_1459226_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 533.0
HFD2_k127_1459915_0 PFAM Glycosyl transferase, group 1 K13057 - 2.4.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 346.0
HFD2_k127_1459915_1 Heat shock 70 kDa protein K04043 - - 0.0000000000000000000000000000000000000000002966 162.0
HFD2_k127_1461897_0 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001752 268.0
HFD2_k127_147580_0 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 411.0
HFD2_k127_147580_1 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 314.0
HFD2_k127_147580_2 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - - - 0.00000000000000000000000000000000000000000000000000000000007435 216.0
HFD2_k127_147580_3 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000009373 146.0
HFD2_k127_147580_4 transcriptional regulator - - - 0.0000000000000000533 83.0
HFD2_k127_147580_5 Cupin - - - 0.0000000002 67.0
HFD2_k127_1477301_0 Uncharacterized protein conserved in bacteria (DUF2330) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004724 269.0
HFD2_k127_1477301_1 Biopolymer transport protein ExbD/TolR - - - 0.00000000000000000000000000000000000000003734 158.0
HFD2_k127_1477301_2 FR47-like protein - - - 0.00000000000000000000000000000000001688 144.0
HFD2_k127_1483351_0 Dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 415.0
HFD2_k127_1483351_1 negative regulation of translational initiation - - - 0.0000000001145 72.0
HFD2_k127_1483351_2 50S ribosome-binding GTPase - - - 0.0003132 49.0
HFD2_k127_1485954_0 SMART Elongator protein 3 MiaB NifB - - - 6.361e-197 626.0
HFD2_k127_1490834_0 ABC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 437.0
HFD2_k127_1505423_0 Vault protein inter-alpha-trypsin domain - - - 0.000000000000000000000000000000000000000000000000000000005204 208.0
HFD2_k127_1505423_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000002925 91.0
HFD2_k127_1507781_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000128 69.0
HFD2_k127_1507781_1 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.000000002036 61.0
HFD2_k127_1507851_0 COG1073 hydrolases of the alpha beta superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009628 378.0
HFD2_k127_1513698_0 Calcineurin-like phosphoesterase K01028,K07098 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003092 417.0
HFD2_k127_1513698_1 regulation of single-species biofilm formation - - - 0.00000000000009512 78.0
HFD2_k127_1519997_0 Family membership K08884 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 314.0
HFD2_k127_1519997_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000002239 196.0
HFD2_k127_1519997_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0006970,GO:0008150,GO:0009266,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000008068 91.0
HFD2_k127_1520882_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 7.449e-262 832.0
HFD2_k127_1520882_1 Methionine aminopeptidase K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000005476 200.0
HFD2_k127_1520882_2 Fibrinogen-related domains (FReDs) - - - 0.0000000000137 76.0
HFD2_k127_1524475_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006495 289.0
HFD2_k127_1524475_1 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005023 291.0
HFD2_k127_1531742_0 Response regulator receiver K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 457.0
HFD2_k127_1534426_0 Belongs to the peptidase M16 family K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 403.0
HFD2_k127_1534426_1 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004197 302.0
HFD2_k127_1534426_2 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000002457 134.0
HFD2_k127_1534426_3 Belongs to the UPF0109 family K06960 - - 0.000000000000000000000008057 103.0
HFD2_k127_1534426_4 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000107 97.0
HFD2_k127_1537048_0 Protein of unknown function (DUF3570) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 336.0
HFD2_k127_1537048_1 ROK family K00886 - 2.7.1.63 0.00000000000000000000000000000000000000000000000000000000000000001983 230.0
HFD2_k127_1538962_0 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 408.0
HFD2_k127_1538962_1 ABC transporter K15738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002327 247.0
HFD2_k127_1538962_2 ATP hydrolysis coupled proton transport - - - 0.000000000000000000000000000000000000000001914 173.0
HFD2_k127_1539191_0 lysine biosynthetic process via aminoadipic acid - - - 0.000000006612 69.0
HFD2_k127_1539191_1 osmolarity-sensing cation channel activity - - - 0.000004655 57.0
HFD2_k127_1539191_2 xylan catabolic process K03932 - - 0.0009028 47.0
HFD2_k127_1543863_0 sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 320.0
HFD2_k127_1543863_2 peptidyl-tyrosine sulfation - - - 0.0003516 49.0
HFD2_k127_1546067_0 poly(R)-hydroxyalkanoic acid synthase K03821 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009058,GO:0016234,GO:0042618,GO:0042619,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0070088,GO:0071704,GO:1901440,GO:1901441,GO:1901576 - 0.00000000000000000000000000000000000000000002678 171.0
HFD2_k127_1546067_1 CsbD-like - - - 0.00000000000000000002004 93.0
HFD2_k127_1546067_3 - - - - 0.0001427 51.0
HFD2_k127_154736_0 histone H2A K63-linked ubiquitination K03404,K07114 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 565.0
HFD2_k127_154736_1 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000009709 237.0
HFD2_k127_154736_2 histone H2A K63-linked ubiquitination - - - 0.000000000000000000000000000000000000000000000003497 186.0
HFD2_k127_154736_3 ABC-type multidrug transport system, ATPase component K01990 - - 0.00000000000000000000000000000000001653 143.0
HFD2_k127_1549055_0 TonB dependent receptor K02014 - - 0.00007169 53.0
HFD2_k127_1552839_0 TonB-dependent Receptor Plug Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008284 447.0
HFD2_k127_1552839_1 Caspase domain - - - 0.00000000000000000000000000000000000000000000000000000001885 215.0
HFD2_k127_1552839_2 Belongs to the ompA family - - - 0.00000233 58.0
HFD2_k127_1556931_0 Beta-ketoacyl synthase, C-terminal domain K16127 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 371.0
HFD2_k127_1557365_0 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain K02488 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 2.7.7.65 0.0000000000000000000000000000000000000008081 167.0
HFD2_k127_1557365_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000005264 97.0
HFD2_k127_1557365_2 EamA-like transporter family - - - 0.0000000000002101 81.0
HFD2_k127_1573354_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 347.0
HFD2_k127_1573354_1 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000005131 234.0
HFD2_k127_1573354_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000001331 211.0
HFD2_k127_1573426_0 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000001437 150.0
HFD2_k127_1573426_1 Lipopolysaccharide biosynthesis protein - - - 0.00000000000000000000000000006886 130.0
HFD2_k127_1573426_2 Glycosyl transferase group 1 - - - 0.00000000000000000004788 102.0
HFD2_k127_1573426_3 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00005725 55.0
HFD2_k127_1575097_0 2-dehydropantoate 2-reductase activity K00077,K04940 - 1.1.1.169,1.5.1.28 0.0000000000000000000000000000009243 131.0
HFD2_k127_1576497_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 1.448e-257 825.0
HFD2_k127_1576497_1 PFAM TPR repeat-containing protein - - - 0.0000000002018 72.0
HFD2_k127_1582284_0 Sulfatase-modifying factor enzyme 1 K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000002347 245.0
HFD2_k127_1590261_0 Calcineurin-like phosphoesterase superfamily domain K03547 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 466.0
HFD2_k127_1590261_1 AAA domain - - - 0.000000000000000000000003548 104.0
HFD2_k127_1593913_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 5.597e-296 920.0
HFD2_k127_1593913_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000101 278.0
HFD2_k127_1602129_0 asparagine synthase K01953,K18316 - 6.3.3.6,6.3.5.4 0.00000004538 65.0
HFD2_k127_1602129_1 (ABC) transporter - - - 0.0000007118 61.0
HFD2_k127_1602129_2 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.00003749 48.0
HFD2_k127_1603266_0 - - - - 0.00000000000000001432 95.0
HFD2_k127_1607956_0 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009103 325.0
HFD2_k127_1607956_1 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 297.0
HFD2_k127_1611354_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K13524 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 363.0
HFD2_k127_1611354_1 Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 324.0
HFD2_k127_1611354_2 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000000513 186.0
HFD2_k127_1617558_0 PAS fold - - - 0.00000000000000000000000000000000000000000000000000000001762 218.0
HFD2_k127_1617558_1 - - - - 0.0001873 51.0
HFD2_k127_1618828_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 595.0
HFD2_k127_1618828_1 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000008225 250.0
HFD2_k127_1618828_2 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000003954 222.0
HFD2_k127_1618828_3 Regulator of chromosome condensation (RCC1) repeat - - - 0.0000000000000000000000000000000000000000000000000000000008026 219.0
HFD2_k127_1618828_4 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000003372 194.0
HFD2_k127_1618828_5 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.00000000000000000000000000000000000002192 145.0
HFD2_k127_1618828_6 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000000008096 76.0
HFD2_k127_1625284_0 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002095 262.0
HFD2_k127_1625284_1 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000001339 225.0
HFD2_k127_1625731_0 PFAM beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001089 282.0
HFD2_k127_1626026_0 Thioredoxin-like domain - - - 0.0000000000001242 78.0
HFD2_k127_1626026_1 Belongs to the CarB family K01955 - 6.3.5.5 0.0000000000005186 74.0
HFD2_k127_1626308_0 Fumarate reductase flavoprotein C-term K00239,K00244 - 1.3.5.1,1.3.5.4 1.394e-306 952.0
HFD2_k127_1626308_1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00241 - - 0.000000000000000000000000000000000005221 148.0
HFD2_k127_1628889_0 endonuclease activity K07451 - - 0.0000000000000000000005441 107.0
HFD2_k127_1628889_1 PFAM von Willebrand factor type A domain - - - 0.00009933 52.0
HFD2_k127_1629548_0 glutamate-cysteine ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006114 494.0
HFD2_k127_1629548_1 Belongs to the aldehyde dehydrogenase family K00128,K00130,K10217 - 1.2.1.3,1.2.1.32,1.2.1.8,1.2.1.85 0.000000000000000000000000000000000000000000000000000002604 196.0
HFD2_k127_1633279_0 drug transmembrane transporter activity K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 497.0
HFD2_k127_1633279_1 - - - - 0.000000000000000000000000000000000000000000000001645 183.0
HFD2_k127_1633870_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000001941 232.0
HFD2_k127_1633870_1 DUF3160 - - - 0.00000000000000000000000000009894 132.0
HFD2_k127_1634636_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000001693 231.0
HFD2_k127_1637489_0 PFAM Mannosyl oligosaccharide glucosidase - - - 3.302e-267 843.0
HFD2_k127_1637489_1 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 334.0
HFD2_k127_1642434_0 TIM-barrel fold metal-dependent hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007261 280.0
HFD2_k127_1642434_1 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000005563 246.0
HFD2_k127_1642434_2 Amidohydrolase family K01465 - 3.5.2.3 0.000000000000000000006128 96.0
HFD2_k127_1642434_3 conserved protein, contains double-stranded beta-helix domain - - - 0.00000000000004825 76.0
HFD2_k127_1646667_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000001908 237.0
HFD2_k127_1646667_1 PilZ domain - - - 0.00000000001255 69.0
HFD2_k127_1651963_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000001957 220.0
HFD2_k127_1653855_0 oxidoreductase activity K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 326.0
HFD2_k127_1653855_1 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001637 289.0
HFD2_k127_1654860_0 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002769 263.0
HFD2_k127_1654860_1 Domain of unknown function (DUF4349) - - - 0.000000000000000000000000000000000000000000001312 177.0
HFD2_k127_165558_0 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004475 280.0
HFD2_k127_165558_1 phosphorelay sensor kinase activity K02342,K02660 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000001727 203.0
HFD2_k127_165558_2 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000002666 184.0
HFD2_k127_1658310_1 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000003447 76.0
HFD2_k127_1658368_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000000000001427 222.0
HFD2_k127_1658368_1 Family membership K12132 - 2.7.11.1 0.00004824 51.0
HFD2_k127_1659139_0 Respiratory-chain NADH dehydrogenase, 30 Kd subunit - - - 8.254e-202 643.0
HFD2_k127_1659139_1 PFAM NADH Ubiquinone plastoquinone (complex I) K12137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 581.0
HFD2_k127_1659139_2 Proton-conducting membrane transporter K12141 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 505.0
HFD2_k127_1659139_3 NADH dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 393.0
HFD2_k127_1659139_4 hydrogenase 4 membrane K12140 - - 0.0000000000000000000000000000000000000000000000000000000000002818 218.0
HFD2_k127_1659139_5 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.00000000000001949 78.0
HFD2_k127_1661582_0 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 337.0
HFD2_k127_1661582_1 SMP-30/Gluconolaconase/LRE-like region - - - 0.00000000000000000001764 94.0
HFD2_k127_166212_0 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309,K11102,K11103 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007969 301.0
HFD2_k127_166212_1 HAMP domain - - - 0.000000000000000000000000000000000000000000000000000000000000008676 228.0
HFD2_k127_166212_2 Bacterial regulatory protein, Fis family - - - 0.00001876 55.0
HFD2_k127_1671567_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 394.0
HFD2_k127_1671567_1 peptidase S9B dipeptidylpeptidase IV domain protein K01278 - 3.4.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006221 375.0
HFD2_k127_1671567_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004596 347.0
HFD2_k127_1671681_0 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000601 168.0
HFD2_k127_1671681_1 Bacterial regulatory proteins, tetR family - - - 0.000000000000000003769 92.0
HFD2_k127_1671681_2 MORN repeat variant - - - 0.000000001987 64.0
HFD2_k127_1674293_0 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000006998 242.0
HFD2_k127_1677959_0 Phosphoenolpyruvate phosphomutase K01841 - 5.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003802 614.0
HFD2_k127_1677959_1 Phosphoesterase - - - 0.000000000000000000000000000000000000000000001506 184.0
HFD2_k127_1677959_2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K09459 - 4.1.1.82 0.000000000000000000000000000000003687 135.0
HFD2_k127_1679033_0 Protein kinase domain K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000001015 278.0
HFD2_k127_1679033_1 NmrA-like family K01784 - 5.1.3.2 0.0000000000000000000000001009 109.0
HFD2_k127_1679516_0 Acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 402.0
HFD2_k127_1679516_2 LD-carboxypeptidase K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000005635 271.0
HFD2_k127_1679516_3 GDP-mannose 4,6 dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000004851 250.0
HFD2_k127_1679516_4 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000002982 172.0
HFD2_k127_1679516_5 Forkhead associated domain - - - 0.00000000000000000000000000001521 126.0
HFD2_k127_1685335_0 ATPase components of ABC transporters with duplicated ATPase domains K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008578 440.0
HFD2_k127_1685335_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 395.0
HFD2_k127_1685335_2 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001892 285.0
HFD2_k127_1685335_3 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins - - - 0.0000000000000000000000000000000000000000000002476 177.0
HFD2_k127_1687860_0 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 356.0
HFD2_k127_1687860_1 FIST N domain - - - 0.00000000000000000000000000000000000000000000000000003402 202.0
HFD2_k127_1687860_2 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.00000000000000000000000000000000003861 154.0
HFD2_k127_1687860_3 Leucine Rich repeat - - - 0.0001137 51.0
HFD2_k127_1689475_0 DUF218 domain - - - 0.000000000000000000000000000000000000000000000000000000434 202.0
HFD2_k127_1689475_1 - - - - 0.00000000000000003675 85.0
HFD2_k127_1694129_0 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000003651 231.0
HFD2_k127_1694129_1 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000000000000000000000003819 177.0
HFD2_k127_1694129_2 protein kinase activity - - - 0.000000001101 64.0
HFD2_k127_1695160_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 490.0
HFD2_k127_1704378_0 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000007387 267.0
HFD2_k127_1704378_1 COG0534 Na -driven multidrug efflux pump K03327 - - 0.000000000000000000000000000000000000000000000000001953 203.0
HFD2_k127_1705291_0 phosphoheptose isomerase K03271,K15669 - 2.7.7.71,5.3.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 308.0
HFD2_k127_1705291_1 PFAM glycosyl transferase family 9 - - - 0.000000000000000000000000000000000000000011 169.0
HFD2_k127_1705291_2 oligosaccharyl transferase activity - - - 0.000000000000000000004128 108.0
HFD2_k127_1706857_0 - - - - 0.00000000000000000000000000006425 126.0
HFD2_k127_1706857_1 protein trimerization K06894,K07114 - - 0.0000000000000006564 83.0
HFD2_k127_1706857_2 BON domain - - - 0.0000004173 61.0
HFD2_k127_1707038_0 PFAM Formylglycine-generating sulfatase enzyme K12132 - 2.7.11.1 0.00000000000000001634 96.0
HFD2_k127_1707840_0 oligosaccharyl transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000044 472.0
HFD2_k127_1707840_1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000004703 237.0
HFD2_k127_1708554_0 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 322.0
HFD2_k127_1708554_1 Subtilase family - - - 0.000000000000000000000000000000000000004667 152.0
HFD2_k127_1719503_0 HD domain - - - 2.19e-239 750.0
HFD2_k127_1719503_1 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000005347 220.0
HFD2_k127_1719503_2 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000004796 147.0
HFD2_k127_1719503_4 Pkd domain containing protein - - - 0.00006841 50.0
HFD2_k127_171984_0 ABC transporter transmembrane region K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 580.0
HFD2_k127_171984_1 Deoxyhypusine synthase K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004647 548.0
HFD2_k127_171984_2 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002143 273.0
HFD2_k127_171984_3 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain - - - 0.0000000000000000000000000000000000000000000003144 175.0
HFD2_k127_171984_4 Carbohydrate family 9 binding domain-like - - - 0.000000000000000000000000000001653 137.0
HFD2_k127_171984_5 Psort location Cytoplasmic, score 8.96 K01163 - - 0.00000000000001631 84.0
HFD2_k127_1721322_0 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000001758 140.0
HFD2_k127_1721322_1 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.0000001167 61.0
HFD2_k127_1721322_2 Serine Threonine protein kinase K12132 - 2.7.11.1 0.0008835 45.0
HFD2_k127_1726192_0 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000004942 215.0
HFD2_k127_1726192_1 Methyltransferase small domain K15460 - 2.1.1.223 0.0000000000000000005468 95.0
HFD2_k127_1726241_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005051 319.0
HFD2_k127_1726241_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000111 243.0
HFD2_k127_1729467_0 ATP-NAD kinase K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 313.0
HFD2_k127_1729467_1 nUDIX hydrolase K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000001236 183.0
HFD2_k127_1729467_2 - - - - 0.00000000000005409 81.0
HFD2_k127_1730800_0 Protein of unknown function (DUF1588) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008309 313.0
HFD2_k127_1731835_0 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000000000000003525 194.0
HFD2_k127_1731835_1 - - - - 0.000000001677 68.0
HFD2_k127_1735054_0 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000002292 82.0
HFD2_k127_1735054_1 Contributes to degradation of proteins cross-linked by transglutaminases by degrading the cross-link between a lysine and a glutamic acid residue. Catalyzes the formation of 5-oxo-L- proline from L-gamma-glutamyl-L-epsilon-lysine. Inactive with L- gamma-glutamyl-alpha-amino acid substrates such as L-gamma- glutamyl-L-alpha-cysteine and L-gamma-glutamyl-L-alpha-alanine K19761 GO:0003674,GO:0003824,GO:0005198,GO:0006807,GO:0007275,GO:0007507,GO:0008150,GO:0008152,GO:0008307,GO:0009056,GO:0016829,GO:0016840,GO:0016842,GO:0032501,GO:0032502,GO:0042219,GO:0048513,GO:0048731,GO:0048856,GO:0061929,GO:0071704,GO:0072359,GO:1901564,GO:1901565,GO:1901575 - 0.000000005924 63.0
HFD2_k127_1735054_4 - - - - 0.0009163 43.0
HFD2_k127_1743052_0 Reductase C-terminal K00529 - 1.18.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 430.0
HFD2_k127_1743052_1 Histidine kinase K08082 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006695 319.0
HFD2_k127_1743052_2 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000000006589 190.0
HFD2_k127_1745239_0 BtpA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006506 248.0
HFD2_k127_1745239_1 - - - - 0.000000000000000000000000000000000000004929 158.0
HFD2_k127_175067_0 Glycosyl transferase family 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005241 548.0
HFD2_k127_175067_1 Bacterial SH3 domain homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000002428 239.0
HFD2_k127_175067_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000002804 242.0
HFD2_k127_175067_3 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000003275 231.0
HFD2_k127_1752871_0 Alpha-2-Macroglobulin K06894 - - 0.0 1168.0
HFD2_k127_1752871_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 344.0
HFD2_k127_1752871_2 PFAM Dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003304 277.0
HFD2_k127_1752871_3 - - - - 0.000000000000000000000000000000000000000000004988 180.0
HFD2_k127_1752871_4 vancomycin resistance protein K18346 - - 0.000000000000000000000000000000004631 142.0
HFD2_k127_1752871_5 - - - - 0.0000000000000004619 82.0
HFD2_k127_1756392_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00836 - 2.6.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 494.0
HFD2_k127_1756392_1 SnoaL-like domain - - - 0.0000004986 51.0
HFD2_k127_1756392_2 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00002207 51.0
HFD2_k127_1758630_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 507.0
HFD2_k127_1758630_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008889 435.0
HFD2_k127_1759149_0 WGR domain protein - - - 0.0000000000000000000000000000000000000000000000000247 189.0
HFD2_k127_1759149_1 Leukotriene A4 hydrolase, C-terminal - - - 0.00000000000000003176 85.0
HFD2_k127_1760358_0 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 619.0
HFD2_k127_1760358_1 Adenylate cyclase - - - 0.0000000000000000002932 96.0
HFD2_k127_1760358_2 Cytochrome P450 - - - 0.000000002413 61.0
HFD2_k127_1764055_0 Parallel beta-helix repeats - - - 0.000000000000000000000000000000000000000000000000000002694 209.0
HFD2_k127_1764986_0 heat shock protein binding - - - 1.529e-228 728.0
HFD2_k127_1764986_1 TIGRFAM cytochrome C family protein - - - 1.246e-198 657.0
HFD2_k127_1764986_2 ferredoxin-NADP+ reductase activity - - - 0.00000000000000000000000000000000000000000000000000000005211 206.0
HFD2_k127_1764986_3 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000002514 196.0
HFD2_k127_1769880_0 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 305.0
HFD2_k127_1769880_1 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000002376 231.0
HFD2_k127_1769880_2 Protein of unknown function (DUF2652) - - - 0.00000000000000000000000000000000000000006802 156.0
HFD2_k127_1771594_0 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 399.0
HFD2_k127_1771594_1 Spermidine synthase K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000009263 188.0
HFD2_k127_1771594_2 Spermine/spermidine synthase domain - - - 0.00000000005356 66.0
HFD2_k127_1779079_0 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000001258 232.0
HFD2_k127_1779226_0 TonB-dependent Receptor Plug Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005548 453.0
HFD2_k127_1779226_1 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 354.0
HFD2_k127_1779226_2 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000746 285.0
HFD2_k127_1779226_3 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000002043 199.0
HFD2_k127_1779226_4 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000001983 188.0
HFD2_k127_1779758_0 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 376.0
HFD2_k127_1779758_1 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 0.000000000000000000000000000000000000006588 153.0
HFD2_k127_1782033_0 cell adhesion involved in biofilm formation - - - 0.000000000000000000004717 105.0
HFD2_k127_1782033_1 polygalacturonase activity K07407 - 3.2.1.22 0.0000000000000001524 84.0
HFD2_k127_1784476_0 Aldo Keto reductase K05275 - 1.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 470.0
HFD2_k127_1784476_1 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000005771 149.0
HFD2_k127_1784476_2 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding - - - 0.000000000000000000000000000000000000451 144.0
HFD2_k127_1785185_0 ChrR Cupin-like domain K07167 - - 0.0000000000000000000000001029 114.0
HFD2_k127_1785185_1 lipolytic protein G-D-S-L family K18650 - 3.2.1.82 0.0000000000000000000001323 109.0
HFD2_k127_1791100_0 cytochrome C peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007397 387.0
HFD2_k127_1794497_0 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000505 307.0
HFD2_k127_1798425_0 Cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000001146 196.0
HFD2_k127_1801170_0 PFAM Beta propeller domain K14475 - - 0.0002223 54.0
HFD2_k127_1802357_0 TonB-dependent Receptor Plug Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005082 444.0
HFD2_k127_180325_0 Family membership K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009839 292.0
HFD2_k127_180325_1 Forkhead associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001143 257.0
HFD2_k127_180325_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000003664 176.0
HFD2_k127_1803338_1 PASTA K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.00000000005044 64.0
HFD2_k127_1803440_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 462.0
HFD2_k127_1803440_1 glutamine-fructose-6-phosphate transaminase (isomerizing) activity K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000001333 264.0
HFD2_k127_1803440_2 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000001203 155.0
HFD2_k127_1813525_0 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000001291 194.0
HFD2_k127_1813525_1 Mitochondrial small ribosomal subunit Rsm22 - - - 0.00000000000000000000000000000000002051 151.0
HFD2_k127_1813796_0 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 331.0
HFD2_k127_1813796_1 Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair K03573 GO:0000018,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009036,GO:0009987,GO:0015666,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0019219,GO:0019222,GO:0031323,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0043765,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000004886 255.0
HFD2_k127_1813796_2 N-4 methylation of cytosine K00571,K03497 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000356 247.0
HFD2_k127_1813796_4 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000003518 178.0
HFD2_k127_1818669_0 von Willebrand factor, type A K11912 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000004696 265.0
HFD2_k127_1818669_1 Thioesterase K07107 - - 0.0000000000000000000000000000000000000000000000009788 186.0
HFD2_k127_1818669_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000005081 161.0
HFD2_k127_1818669_3 Memo-like protein K06990 - - 0.0000000000000001322 80.0
HFD2_k127_1821190_0 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008719 481.0
HFD2_k127_1821190_1 dehydrogenase complex catalyzes the overall conversion of - - - 0.00000000000000000000000000000009386 139.0
HFD2_k127_1821190_2 Ferredoxin - - - 0.000000000000000000000004078 108.0
HFD2_k127_1821190_3 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000007383 74.0
HFD2_k127_1821939_0 PFAM sigma-54 factor interaction domain-containing protein K07715 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004268 317.0
HFD2_k127_1826140_0 CBD_II K01179,K01183 - 3.2.1.14,3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 300.0
HFD2_k127_1826140_1 cell envelope organization K05807,K08309 - - 0.000000000000000000000000001104 125.0
HFD2_k127_1835243_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 302.0
HFD2_k127_1835243_1 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000006563 242.0
HFD2_k127_1835243_2 PFAM ATP-binding region, ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000003378 201.0
HFD2_k127_1839448_0 Uncharacterized protein conserved in bacteria (DUF2330) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004878 264.0
HFD2_k127_1839448_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.000000000000000000000000000000000000000000000000000000000000000000003908 243.0
HFD2_k127_1839496_0 Exonuclease - - - 0.000000000000000000000000000000000000000000000002212 176.0
HFD2_k127_1839496_1 Belongs to the peptidase S1B family - - - 0.000000000000000005501 96.0
HFD2_k127_1839496_2 Bacterial SH3 domain homologues - - - 0.00000003332 64.0
HFD2_k127_1840388_0 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000001122 93.0
HFD2_k127_1840388_1 PFAM Dockerin type - - - 0.0000000000002007 81.0
HFD2_k127_1845093_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008042 396.0
HFD2_k127_1845093_1 Flagellar protein export ATPase FliI K02412 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000005596 198.0
HFD2_k127_1847934_0 Phosphoesterase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002071 255.0
HFD2_k127_1847934_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001311 238.0
HFD2_k127_1847934_2 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000001236 244.0
HFD2_k127_1847934_3 Histidine kinase - - - 0.0000000000000000002569 98.0
HFD2_k127_1847934_4 Involved in the tonB-independent uptake of proteins - - - 0.000000000002998 73.0
HFD2_k127_1847934_5 Belongs to the peptidase S1B family - - - 0.00000001597 66.0
HFD2_k127_1849491_0 FAD linked oxidases, C-terminal domain K00102,K00104 - 1.1.2.4,1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004618 443.0
HFD2_k127_1849491_1 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000005634 181.0
HFD2_k127_1851588_0 Family membership K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005752 291.0
HFD2_k127_1851588_1 Tetratricopeptide repeat - - - 0.0000000000000000000000003546 119.0
HFD2_k127_1851588_2 - - - - 0.00000001026 57.0
HFD2_k127_1851855_0 FecR protein - - - 0.000000000007391 72.0
HFD2_k127_1851855_1 Involved in the tonB-independent uptake of proteins - - - 0.0000003652 62.0
HFD2_k127_1861927_0 ABC transporter K06020 - 3.6.3.25 1.327e-224 706.0
HFD2_k127_1861927_1 Poly (ADP-ribose) polymerase K10798 GO:0001101,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0003950,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006464,GO:0006471,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009719,GO:0009725,GO:0009737,GO:0009987,GO:0010033,GO:0016070,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016886,GO:0019538,GO:0022616,GO:0033554,GO:0033993,GO:0034641,GO:0034645,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0097305,GO:0140097,GO:1901360,GO:1901564,GO:1901576,GO:1901700 2.4.2.30 0.0000000001776 68.0
HFD2_k127_1867432_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008029 551.0
HFD2_k127_1867432_1 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000001487 246.0
HFD2_k127_1867432_2 Macro domain - - - 0.00000000000000000001979 96.0
HFD2_k127_1868517_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 553.0
HFD2_k127_1872528_0 Circadian K08482 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 417.0
HFD2_k127_1872528_1 Cytochrome c - - - 0.0000000000000000000000001242 118.0
HFD2_k127_1872528_2 response regulator - - - 0.000000000000000003025 93.0
HFD2_k127_1872528_3 Histidine kinase - - - 0.000000000000004005 82.0
HFD2_k127_1875552_0 TonB-dependent Receptor Plug Domain - - - 0.0000000000000000000000000000000000000000000000000003424 199.0
HFD2_k127_1875552_1 AAA domain - - - 0.000000009533 64.0
HFD2_k127_188281_0 Oligonucleotide/oligosaccharide-binding (OB)-fold K03578,K03579 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 389.0
HFD2_k127_188281_1 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000000000000000356 103.0
HFD2_k127_1884222_0 Phospholipase D. Active site motifs. K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005301 255.0
HFD2_k127_1884222_1 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000007458 184.0
HFD2_k127_1884222_2 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.0000000000000000000000000000401 121.0
HFD2_k127_1884222_3 Thiamine biosynthesis K03154 - - 0.000000000000000003103 85.0
HFD2_k127_188639_0 Belongs to the serpin family K13963 - - 0.000000000000000000000000000000000000001934 159.0
HFD2_k127_188639_1 Domain of unknown function (DUF1963) - - - 0.0003666 52.0
HFD2_k127_1887053_0 chlorophyll binding K16191,K20276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002479 263.0
HFD2_k127_1887053_2 Maf-like protein K06287 - - 0.0000001471 63.0
HFD2_k127_1888654_0 Histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002782 473.0
HFD2_k127_1888654_1 Response regulator receiver - - - 0.00000000000000000000000000001126 138.0
HFD2_k127_1888654_2 Stress-induced bacterial acidophilic repeat motif K06884 - - 0.00000000000249 72.0
HFD2_k127_1888654_3 Peptidase family C25 - - - 0.000000003696 70.0
HFD2_k127_1892734_0 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002877 541.0
HFD2_k127_1893181_0 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000006634 235.0
HFD2_k127_1893181_1 Major Facilitator Superfamily K07783 - - 0.0000000000000000000000000000000000000000000000000001319 203.0
HFD2_k127_1893181_2 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000001028 68.0
HFD2_k127_1893181_3 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.00000008369 57.0
HFD2_k127_1893472_0 Belongs to the peptidase M16 family K07263 - - 0.0000000000000000000000000007829 118.0
HFD2_k127_1893472_1 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB - - - 0.0000000000001107 79.0
HFD2_k127_1893472_2 structural constituent of cell wall - - - 0.00000007811 63.0
HFD2_k127_189499_0 - - - - 0.000000000000000000000000000006105 129.0
HFD2_k127_189499_1 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.0000000000001236 80.0
HFD2_k127_189499_2 protein with SCP PR1 domains - - - 0.0002845 49.0
HFD2_k127_1895169_0 WD40 repeat-like protein - - - 0.000006465 60.0
HFD2_k127_1897790_0 Belongs to the argininosuccinate synthase family. Type K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 618.0
HFD2_k127_1897790_1 stress-induced mitochondrial fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 329.0
HFD2_k127_1897790_3 phosphorelay signal transduction system K01768,K10941,K11894 - 4.6.1.1 0.0000000000000000504 85.0
HFD2_k127_1898022_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000215 142.0
HFD2_k127_1898022_1 Ketopantoate reductase PanE/ApbA C terminal - - - 0.0000000000000000000000000000731 122.0
HFD2_k127_1898022_2 Protein of unknown function (DUF1298) K00635 - 2.3.1.20 0.0007585 46.0
HFD2_k127_1901890_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009374 447.0
HFD2_k127_1901890_1 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007915 353.0
HFD2_k127_1901890_2 pseudouridine synthase activity K06178,K06183,K07058 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.22 0.0000000000000000001506 102.0
HFD2_k127_1904761_0 Belongs to the heme-copper respiratory oxidase family - - - 4.972e-285 893.0
HFD2_k127_1904761_1 Cytochrome c oxidase subunit K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000006403 239.0
HFD2_k127_1904761_2 PFAM Rieske 2Fe-2S domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000002528 217.0
HFD2_k127_1904761_3 cytochrome c oxidase K02862 - - 0.000000000000000000000000000000000000000000000000009496 192.0
HFD2_k127_1914736_0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 387.0
HFD2_k127_1914736_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005384 303.0
HFD2_k127_1915369_0 Domain of unknown function (DUF4132) - - - 0.00000000000000000000004845 116.0
HFD2_k127_1915949_0 Protein of unknown function (DUF533) K11962 - - 0.0000000000000000000000000000000005595 135.0
HFD2_k127_1915949_1 - - - - 0.0000000001932 73.0
HFD2_k127_1915949_2 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.0006651 43.0
HFD2_k127_1920043_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 579.0
HFD2_k127_1920043_1 Alpha beta hydrolase - - - 0.0000000000000000000005946 101.0
HFD2_k127_1920043_2 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000006492 72.0
HFD2_k127_1933390_0 - - - - 0.000000000000000000000000000000000000000000000000000000001144 225.0
HFD2_k127_1933390_1 Peptidase family M1 domain K01256 - 3.4.11.2 0.00000000006247 66.0
HFD2_k127_1943269_0 Found in ATP-dependent protease La (LON) K01338 - 3.4.21.53 4.137e-205 652.0
HFD2_k127_1943269_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007224 390.0
HFD2_k127_1947122_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 0.0 1267.0
HFD2_k127_1947122_1 Stage II sporulation E family protein K07315 - 3.1.3.3 0.000000000000000005598 92.0
HFD2_k127_1947122_3 Low-density lipoprotein receptor domain class A - - - 0.000000001975 69.0
HFD2_k127_1949899_0 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001317 258.0
HFD2_k127_1949899_1 Calcium ion binding - GO:0002009,GO:0002165,GO:0003674,GO:0005198,GO:0005201,GO:0005575,GO:0005576,GO:0007275,GO:0007424,GO:0007444,GO:0007472,GO:0007475,GO:0007476,GO:0007552,GO:0007560,GO:0007591,GO:0008150,GO:0008362,GO:0008587,GO:0009653,GO:0009791,GO:0009886,GO:0009887,GO:0009888,GO:0022404,GO:0031012,GO:0032501,GO:0032502,GO:0035107,GO:0035114,GO:0035120,GO:0035220,GO:0035239,GO:0035295,GO:0040003,GO:0040005,GO:0042303,GO:0042335,GO:0044421,GO:0044719,GO:0048513,GO:0048563,GO:0048569,GO:0048707,GO:0048729,GO:0048731,GO:0048736,GO:0048737,GO:0048856,GO:0060429,GO:0060541,GO:0060562,GO:0065007,GO:0065008,GO:0090066 - 0.0000002464 62.0
HFD2_k127_1950040_0 Methyltransferase domain - - - 0.000000000001088 72.0
HFD2_k127_1950040_1 Proposed nucleic acid binding domain - - - 0.000926 52.0
HFD2_k127_1951534_0 Protein containing a von Willebrand factor type A domain - - - 4.969e-235 751.0
HFD2_k127_1955343_0 Belongs to the HAD-like hydrolase superfamily. PhnX family K05306 - 3.11.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000605 340.0
HFD2_k127_1955343_1 Calcineurin-like phosphoesterase K14379 - 3.1.3.2 0.00000000000000000000000000000000000000000000000000002413 201.0
HFD2_k127_1955343_2 PFAM Rhomboid family - - - 0.000000000000000000000000000000000000003708 155.0
HFD2_k127_1955887_0 phosphorelay signal transduction system K10941 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006262 346.0
HFD2_k127_1957275_1 membrane organization - - - 0.0000000007791 61.0
HFD2_k127_1962130_0 PFAM Glycosyl transferase, group 1 - - - 2.256e-221 709.0
HFD2_k127_1962130_1 beta-1,4-mannooligosaccharide phosphorylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000055 520.0
HFD2_k127_1962130_2 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000003165 213.0
HFD2_k127_1962130_3 Sel1-like repeats. K07126 - - 0.0000000000000000000000000000000000000000000000000000179 205.0
HFD2_k127_1962130_4 Transcription factor zinc-finger K09981 - - 0.00000006571 61.0
HFD2_k127_1968723_0 intracellular protease amidase - - - 0.00000000000000000000000000003651 132.0
HFD2_k127_1968723_1 cytokinin biosynthetic process - - - 0.0000000000000000000000000014 124.0
HFD2_k127_1995612_0 Uncharacterized protein conserved in bacteria (DUF2062) - - - 0.0000000000000000000000000000000000000000000001116 183.0
HFD2_k127_1995612_1 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.00000000000000000002128 106.0
HFD2_k127_1995612_2 COG1404 Subtilisin-like serine proteases K14645 - - 0.00000000000005738 73.0
HFD2_k127_1995739_0 Cytochrome C assembly protein K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003366 320.0
HFD2_k127_1995739_1 Heat shock 70 kDa protein K04043 - - 0.0000000000000000000000000000003389 137.0
HFD2_k127_1995739_4 DnaJ molecular chaperone homology domain K05516 - - 0.0001401 51.0
HFD2_k127_2005334_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 3.05e-256 801.0
HFD2_k127_2005334_1 AAA ATPase domain - - - 0.000000000000000000001268 107.0
HFD2_k127_2006154_0 carboxylic ester hydrolase activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000007845 197.0
HFD2_k127_2006154_1 Methyltransferase domain - - - 0.000000000000000000000000000000000006993 146.0
HFD2_k127_2006154_2 - - - - 0.00009197 52.0
HFD2_k127_200780_0 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000001151 238.0
HFD2_k127_200780_1 PFAM peptidase K01284,K01414 - 3.4.15.5,3.4.24.70 0.000000000000000009392 83.0
HFD2_k127_2014658_0 Bacterial regulatory helix-turn-helix protein, lysR family K04761 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 294.0
HFD2_k127_2014658_1 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000396 289.0
HFD2_k127_2014658_2 Family membership K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000001278 274.0
HFD2_k127_2014658_3 Copper type II ascorbate-dependent monooxygenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000744 220.0
HFD2_k127_2014658_4 PEGA domain - - - 0.000000000000000000000000000002827 135.0
HFD2_k127_2014658_5 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.0000000001461 64.0
HFD2_k127_2014658_6 Tetratricopeptide repeat - - - 0.00002525 55.0
HFD2_k127_2016683_0 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004838 362.0
HFD2_k127_2016683_1 xyloglucan:xyloglucosyl transferase activity K01186,K12373,K20830 - 3.2.1.178,3.2.1.18,3.2.1.52 0.000000000000000000000000001084 126.0
HFD2_k127_2016683_2 - - - - 0.000000000000000000002784 100.0
HFD2_k127_2016683_3 - - - - 0.00000000001049 68.0
HFD2_k127_2016683_4 - - - - 0.00004989 52.0
HFD2_k127_2016732_0 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008369 284.0
HFD2_k127_2023095_0 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00571,K00847,K00852 - 2.1.1.72,2.7.1.15,2.7.1.4 0.00000000000000000000000000000000000000006124 157.0
HFD2_k127_2023095_1 Thioredoxin-like - - - 0.000000000000000000000000000007585 124.0
HFD2_k127_2023095_2 - - - - 0.0000008627 62.0
HFD2_k127_2027330_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 511.0
HFD2_k127_2027330_1 CHAD - - - 0.000000000000000000003813 108.0
HFD2_k127_2032028_0 Putative modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005132 458.0
HFD2_k127_2032028_1 Tetratricopeptide repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000005326 239.0
HFD2_k127_203335_0 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 297.0
HFD2_k127_203335_1 Phosphate transport system permease protein PstA K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002858 265.0
HFD2_k127_203335_2 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001095 272.0
HFD2_k127_203335_3 Histidine kinase K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000007717 231.0
HFD2_k127_203335_4 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000997 147.0
HFD2_k127_2035684_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000002873 228.0
HFD2_k127_2035684_1 Putative restriction endonuclease - - - 0.0000000000000000000000000000000000000001739 157.0
HFD2_k127_20431_0 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000002493 206.0
HFD2_k127_20431_1 oxidoreductase activity K07114 - - 0.00000000000000000000000000000000001923 150.0
HFD2_k127_20431_2 Sulfatase - - - 0.0000005968 56.0
HFD2_k127_2048994_0 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00756,K00758 - 2.4.2.2,2.4.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 563.0
HFD2_k127_2048994_1 Saccharopine dehydrogenase NADP binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005518 406.0
HFD2_k127_2048994_2 WYL domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001262 244.0
HFD2_k127_2050247_0 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 415.0
HFD2_k127_2050247_1 Type II secretion system (T2SS), protein F K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005373 379.0
HFD2_k127_2052223_0 OmpA family K03286 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009201 303.0
HFD2_k127_2052223_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000009299 91.0
HFD2_k127_2056881_0 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 330.0
HFD2_k127_2056881_1 - - - - 0.00000000000000000000000000000000000017 156.0
HFD2_k127_2058643_0 PFAM General substrate transporter K03761 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 443.0
HFD2_k127_2058643_1 Sulfatase-modifying factor enzyme 1 K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000009678 244.0
HFD2_k127_2060718_0 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 577.0
HFD2_k127_2060718_1 HEAT repeats - - - 0.0000000000000000000000000006572 126.0
HFD2_k127_2060718_2 Haloacid dehalogenase-like hydrolase domain-containing protein - - - 0.000000004686 68.0
HFD2_k127_2071246_0 5'-nucleotidase, C-terminal domain K01081 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 497.0
HFD2_k127_2079342_0 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000001412 243.0
HFD2_k127_2079342_1 - - - - 0.0000000000000000000000000000000000000000000000000000003409 208.0
HFD2_k127_2079342_2 PilZ domain - - - 0.0000000000000003264 87.0
HFD2_k127_2079363_0 PEGA domain - - - 0.000000000000000000000000000000000000000000000000000002874 202.0
HFD2_k127_2079363_1 - - - - 0.00000000000000000000000000000000000000008097 175.0
HFD2_k127_2086386_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 459.0
HFD2_k127_2086386_1 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006732 402.0
HFD2_k127_2086386_2 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 382.0
HFD2_k127_2087722_0 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001113 297.0
HFD2_k127_2089663_0 - - - - 0.00000000000000000000000000000000000000000000001328 177.0
HFD2_k127_2089663_1 Uncharacterised conserved protein (DUF2228) - - - 0.00000000000000000000000000000000000003161 160.0
HFD2_k127_2089663_2 YjbR - - - 0.00000000000000000000000000000001057 134.0
HFD2_k127_2089663_3 DNA ligase OB-like domain K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000017 89.0
HFD2_k127_2089663_4 amine dehydrogenase activity - - - 0.0000000001834 72.0
HFD2_k127_2095800_0 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000002141 149.0
HFD2_k127_2095800_1 - - - - 0.000000000000000000000000000009824 125.0
HFD2_k127_2101932_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 445.0
HFD2_k127_2101932_1 Protein of unknown function (DUF520) K09767 - - 0.000000000000000000000000000000000000000004162 159.0
HFD2_k127_2101932_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0007497 46.0
HFD2_k127_2103963_0 trisaccharide binding - - - 1.933e-261 824.0
HFD2_k127_2103963_1 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 355.0
HFD2_k127_2103963_2 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 313.0
HFD2_k127_2103963_3 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000005168 177.0
HFD2_k127_2106707_0 Two component, sigma54 specific, transcriptional regulator, Fis family K07712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000964 415.0
HFD2_k127_2106707_1 phosphorelay sensor kinase activity K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000833 282.0
HFD2_k127_2106707_2 Hsp20/alpha crystallin family K13993 - - 0.0004646 47.0
HFD2_k127_2111878_0 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002603 270.0
HFD2_k127_2112715_0 Domain of unknown function (DUF4132) - - - 0.000000000000000000000000000000000000000000000000000000000000000000002294 257.0
HFD2_k127_2112715_1 Dihydroxyacetone kinase K00863,K05878 - 2.7.1.121,2.7.1.28,2.7.1.29,4.6.1.15 0.00000000000001726 75.0
HFD2_k127_2116000_0 TRAP transporter T-component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009875 279.0
HFD2_k127_2116000_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000006793 235.0
HFD2_k127_2116000_2 Beta propeller domain - - - 0.000000000000000004003 87.0
HFD2_k127_2120212_0 transferase activity, transferring glycosyl groups K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 616.0
HFD2_k127_2130248_0 Biopolymer transport protein ExbD/TolR - - - 0.000000008897 66.0
HFD2_k127_2130248_1 Biopolymer transport protein ExbD/TolR - - - 0.0001967 53.0
HFD2_k127_2137971_0 Sulfatase-modifying factor enzyme 1 K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000154 250.0
HFD2_k127_2137971_1 - - - - 0.000000000000000000000000000000000000000000000000000000009053 212.0
HFD2_k127_2141829_1 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007682 533.0
HFD2_k127_2141829_2 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000001146 254.0
HFD2_k127_2141829_3 DNA methylase K00571,K07316 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000813 197.0
HFD2_k127_2153318_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.00000000000000000000000000000000000000000000000000000000000000000007797 241.0
HFD2_k127_2153318_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0000000000000000000000000000000000000000000000000001906 193.0
HFD2_k127_2154383_0 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 295.0
HFD2_k127_2154383_1 - - - - 0.000000000000000000000000000000000000000000000002668 189.0
HFD2_k127_2154383_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000003224 101.0
HFD2_k127_2154596_0 all-trans-retinol 13,14-reductase activity K09516,K09835 - 1.3.99.23,5.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000153 276.0
HFD2_k127_2162105_0 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009771 432.0
HFD2_k127_2162105_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003823 276.0
HFD2_k127_2162105_2 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.000000001889 65.0
HFD2_k127_2165922_0 Hydrolase - - - 0.000000000000000000000000001431 129.0
HFD2_k127_2165922_1 - - - - 0.00000000000000000000000001502 118.0
HFD2_k127_2172713_0 Belongs to the glycosyl hydrolase 13 family K01200,K01214 - 3.2.1.41,3.2.1.68 2.74e-221 710.0
HFD2_k127_2172713_1 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.000000000000001753 90.0
HFD2_k127_2172713_2 PFAM helix-turn-helix- domain containing protein, AraC type - - - 0.00000000000353 78.0
HFD2_k127_2174677_0 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 497.0
HFD2_k127_2174677_1 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000003179 158.0
HFD2_k127_2176729_0 Family membership K08884 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004358 316.0
HFD2_k127_2176729_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000537 161.0
HFD2_k127_2176729_2 carbohydrate binding K10059,K17513 - - 0.000391 51.0
HFD2_k127_2180370_0 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 579.0
HFD2_k127_2180370_1 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000006057 257.0
HFD2_k127_2180370_2 Tetratricopeptide repeat - - - 0.00000000000000000000000001573 113.0
HFD2_k127_2180370_3 GAF domain - - - 0.0000000000008461 70.0
HFD2_k127_2185756_0 PFAM TonB-dependent Receptor K16091 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 343.0
HFD2_k127_2185756_1 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000008649 142.0
HFD2_k127_2185816_0 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006425 377.0
HFD2_k127_2185816_1 SERine Proteinase INhibitors K13963 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003857 284.0
HFD2_k127_2188378_0 Glycosyltransferase K20534 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 331.0
HFD2_k127_2188378_1 Methyltransferase domain - - - 0.00000000001147 74.0
HFD2_k127_2188378_2 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.0000000001335 64.0
HFD2_k127_2197089_0 ATP-dependent DNA helicase RecQ K03169 - 5.99.1.2 0.0 1302.0
HFD2_k127_2197089_1 Evidence 5 No homology to any previously reported sequences - - - 0.000000000000000000000000000000000000000000000000008571 188.0
HFD2_k127_2206793_0 Forkhead associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 487.0
HFD2_k127_2207304_1 - - - - 0.0001722 53.0
HFD2_k127_2207304_2 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0001975 48.0
HFD2_k127_2207441_0 Family membership K08884 - 2.7.11.1 0.000000000000000000000000000000000001131 155.0
HFD2_k127_2207947_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006072 591.0
HFD2_k127_2207947_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K17722 - 1.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001233 278.0
HFD2_k127_2207947_2 Carbon-nitrogen hydrolase K01431,K12251 - 3.5.1.53,3.5.1.6 0.0000000000000000000000000000001225 124.0
HFD2_k127_2214178_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008085 521.0
HFD2_k127_2214178_1 PFAM Type II secretion system protein E K02454,K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 376.0
HFD2_k127_2220248_0 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000002876 234.0
HFD2_k127_2220248_1 - - - - 0.000000000000000000001019 107.0
HFD2_k127_2221279_0 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.00000000000000000000000000000002413 138.0
HFD2_k127_2225275_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000000000000000000000000000000000000000000000000001577 209.0
HFD2_k127_2227518_0 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 463.0
HFD2_k127_2227518_1 - - - - 0.000000000000000000000000000000000000000000000000003793 192.0
HFD2_k127_2227518_2 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000009597 111.0
HFD2_k127_2239641_0 TIGRFAM phosphate phosphite phosphonate ABC transporters, periplasmic binding protein K02044 - - 0.0000000000000000004125 98.0
HFD2_k127_2239641_1 Beta-lactamase K01286 - 3.4.16.4 0.000000579 59.0
HFD2_k127_2239641_2 VanZ like family - - - 0.00001406 53.0
HFD2_k127_224041_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 421.0
HFD2_k127_224041_1 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01006,K22424 - 2.7.3.13,2.7.9.1 0.000000000000002198 79.0
HFD2_k127_2240486_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity - - - 0.0000000004158 72.0
HFD2_k127_2241322_0 Pfam Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000427 567.0
HFD2_k127_2241322_1 membrane protein TerC - - - 0.000000000000000000000000000000000000000000000000000000000000001656 229.0
HFD2_k127_2241322_2 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169,K03737 - 1.2.7.1 0.000000000000000000000000000000000000000000000001286 177.0
HFD2_k127_2242235_0 Belongs to the mandelate racemase muconate lactonizing enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008206 297.0
HFD2_k127_2242235_1 Peptidase family M3 K01392 - 3.4.24.15 0.000000000000000000000000000000000000000000000000000000000000000002377 230.0
HFD2_k127_2242235_2 - - - - 0.0000000000000000000000000000000000000000003988 168.0
HFD2_k127_2247139_1 40-residue YVTN family beta-propeller repeat protein - - - 0.00000002552 64.0
HFD2_k127_2249861_0 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802 - 5.2.1.8 0.000002304 49.0
HFD2_k127_2253370_0 metallopeptidase activity K01081,K01179,K01183,K20276 - 3.1.3.5,3.2.1.14,3.2.1.4 0.0000000000000000000000000000000000000000000000003259 185.0
HFD2_k127_2261311_0 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005054 264.0
HFD2_k127_2261311_1 Copper binding proteins, plastocyanin/azurin family - - - 0.0009972 48.0
HFD2_k127_227012_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000004315 117.0
HFD2_k127_227012_1 - - - - 0.000000000000000000000000002987 123.0
HFD2_k127_227012_2 ECF sigma factor - - - 0.0005415 49.0
HFD2_k127_2270479_0 Family membership K08884 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 305.0
HFD2_k127_2270479_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000007608 177.0
HFD2_k127_2270479_2 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000001335 173.0
HFD2_k127_2289201_0 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 351.0
HFD2_k127_2289201_1 Cytochrome c - - - 0.00000000000006026 75.0
HFD2_k127_2290191_0 - - - - 0.00000000000000000000000000000000000000001187 169.0
HFD2_k127_2290191_1 - - - - 0.000000000000003996 81.0
HFD2_k127_2290664_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005722 372.0
HFD2_k127_2290664_2 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000005241 199.0
HFD2_k127_2294057_0 S-acyltransferase activity K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000001433 252.0
HFD2_k127_2294057_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000009755 83.0
HFD2_k127_2294057_2 - - - - 0.00000016 61.0
HFD2_k127_2294057_3 cytochrome C peroxidase - - - 0.0000005024 59.0
HFD2_k127_2294057_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0001546 46.0
HFD2_k127_2294347_0 ATP:ADP antiporter activity K03301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005642 319.0
HFD2_k127_2294347_1 cyclic nucleotide binding K00384,K10914,K16922 - 1.8.1.9 0.000000000000000000000000000000000000000659 161.0
HFD2_k127_2294347_2 ATP:ADP antiporter activity K03301 - - 0.000000000000000008336 93.0
HFD2_k127_2297959_0 Protein kinase domain K08884 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000003759 263.0
HFD2_k127_2297959_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000002145 111.0
HFD2_k127_2297959_2 membrane K06377 - - 0.000003122 55.0
HFD2_k127_2311735_0 PFAM Formylglycine-generating sulfatase enzyme K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002689 298.0
HFD2_k127_2311735_1 PFAM Formylglycine-generating sulfatase enzyme K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008638 286.0
HFD2_k127_2311735_2 PEGA domain - - - 0.000000000000000000000000000000000000000000000000000133 199.0
HFD2_k127_2311735_3 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000009837 141.0
HFD2_k127_2316850_0 NmrA-like family K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 317.0
HFD2_k127_2316850_1 transcriptional regulator - - - 0.000000000000000000000000000003165 130.0
HFD2_k127_2316850_2 - - - - 0.00000000000000000000003074 107.0
HFD2_k127_2318215_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005542 244.0
HFD2_k127_2318215_1 guanyl-nucleotide exchange factor activity K01179,K01183,K02034 - 3.2.1.14,3.2.1.4 0.000000001865 70.0
HFD2_k127_2319883_0 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000007188 268.0
HFD2_k127_2319883_1 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000001908 233.0
HFD2_k127_2319883_2 Pyrrolo-quinoline quinone - - - 0.000000000000000000000000000000007099 132.0
HFD2_k127_2319883_3 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.0000000000000000000000008588 111.0
HFD2_k127_2319883_4 Bacterial regulatory proteins, tetR family - - - 0.0000000000382 71.0
HFD2_k127_2321134_0 Protein-disulfide isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 320.0
HFD2_k127_2321134_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000005523 168.0
HFD2_k127_2327271_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 1.992e-202 640.0
HFD2_k127_2327271_1 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000001375 254.0
HFD2_k127_2327271_2 Diadenosine tetraphosphatase and related serine threonine protein phosphatases K07313 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000001327 238.0
HFD2_k127_2327271_3 XdhC Rossmann domain K07402 - - 0.000000000000000000000000000000000000000000000000000000000000001431 239.0
HFD2_k127_2327271_4 pyrroloquinoline quinone binding - - - 0.00000000002241 76.0
HFD2_k127_2327271_5 Universal stress protein - - - 0.00003046 49.0
HFD2_k127_2331925_0 Cytochrome P450 - - - 0.00000000000000000000000000000000000000000000006932 180.0
HFD2_k127_2331925_1 Superfamily II DNA RNA helicases, SNF2 family - - - 0.000000000000000000000008265 105.0
HFD2_k127_2331925_2 helix_turn_helix, Lux Regulon - - - 0.00000005498 61.0
HFD2_k127_2334680_0 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009365 355.0
HFD2_k127_2336730_0 Esterase PHB depolymerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001093 258.0
HFD2_k127_2336904_0 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000001976 237.0
HFD2_k127_2336904_1 palmitoyl-(protein) hydrolase activity - - - 0.00000000000000209 87.0
HFD2_k127_2340917_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 372.0
HFD2_k127_2340917_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009091 396.0
HFD2_k127_2342876_0 alpha/beta hydrolase fold K01066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000666 259.0
HFD2_k127_2342876_1 Putative zinc-binding metallo-peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000003093 237.0
HFD2_k127_2342876_2 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides - - - 0.00000000000000000000000000115 115.0
HFD2_k127_2344985_0 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000009413 91.0
HFD2_k127_2345185_0 Protein of unknown function (DUF2961) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 576.0
HFD2_k127_2345185_1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000001696 240.0
HFD2_k127_2345185_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000002123 226.0
HFD2_k127_2345185_3 Biopolymer transport protein ExbD/TolR - - - 0.0002515 52.0
HFD2_k127_2345482_0 Peptidase family M3 K01284 - 3.4.15.5 1.392e-316 980.0
HFD2_k127_2353666_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 2.052e-228 720.0
HFD2_k127_2353666_1 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 310.0
HFD2_k127_2353666_2 DNA-binding transcription factor activity - - - 0.00000000000002874 84.0
HFD2_k127_2363415_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004452 300.0
HFD2_k127_2363415_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002787 278.0
HFD2_k127_2363415_2 NAD(P)H-dependent FMN reductase K19784 - - 0.00000000000000000000000000000000000000000000000000000000000007061 218.0
HFD2_k127_2363415_3 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000000000000009764 217.0
HFD2_k127_2365106_0 Pfam:DUF955 K07110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003344 590.0
HFD2_k127_2365106_1 Belongs to the malate synthase family K01638 - 2.3.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004144 463.0
HFD2_k127_2365106_2 - - - - 0.00000000000000003255 89.0
HFD2_k127_2374732_0 peptidyl-tyrosine sulfation - - - 0.0000000000004532 74.0
HFD2_k127_2374732_1 domain, Protein K07654 - 2.7.13.3 0.000000006572 69.0
HFD2_k127_2374732_2 Domain of unknown function (DUF4215) - - - 0.000005303 59.0
HFD2_k127_2383891_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 2.672e-218 682.0
HFD2_k127_2383891_1 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000000000000000001471 130.0
HFD2_k127_23859_0 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000009471 136.0
HFD2_k127_23859_1 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000001124 124.0
HFD2_k127_23859_2 lyase activity - - - 0.0000008716 61.0
HFD2_k127_23859_3 zinc metallopeptidase K06973 - - 0.0001721 50.0
HFD2_k127_2387721_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000003425 217.0
HFD2_k127_2387721_1 PFAM Protein kinase domain K08309 - - 0.0000000000002251 78.0
HFD2_k127_239047_0 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 377.0
HFD2_k127_239047_1 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000003859 153.0
HFD2_k127_2399775_1 Two component regulator propeller - - - 0.0000000000000000004848 88.0
HFD2_k127_2407848_0 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007108 451.0
HFD2_k127_2407848_1 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000001252 191.0
HFD2_k127_2408392_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000002044 206.0
HFD2_k127_2408392_2 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000001261 79.0
HFD2_k127_2411024_0 Glucose-1-phosphate cytidylyltransferase K00978 - 2.7.7.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 383.0
HFD2_k127_2411024_1 PFAM NAD dependent epimerase dehydratase family K19180 - 1.1.1.339 0.00000000000000000000000000000000000000000000000000000000003932 216.0
HFD2_k127_2420395_0 Belongs to the CarA family K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 366.0
HFD2_k127_2420395_1 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity K01955 - 6.3.5.5 0.00000000000000000000000000000002568 129.0
HFD2_k127_2423335_0 alpha/beta hydrolase fold K00641 - 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005491 300.0
HFD2_k127_2423682_0 AAA domain (dynein-related subfamily) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 566.0
HFD2_k127_2423682_1 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000002231 218.0
HFD2_k127_2423682_2 Peptidase M22 K14742 - - 0.00005153 47.0
HFD2_k127_2427536_0 Uncharacterized protein conserved in bacteria (DUF2330) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004858 282.0
HFD2_k127_2427536_1 Uncharacterized protein conserved in bacteria (DUF2330) - - - 0.000000000000000005284 94.0
HFD2_k127_2439609_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007081 424.0
HFD2_k127_2439609_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000437 350.0
HFD2_k127_2439609_2 PFAM regulator of chromosome condensation, RCC1 - - - 0.00000009815 62.0
HFD2_k127_2451706_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006519 541.0
HFD2_k127_2451706_1 Lamin Tail Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 554.0
HFD2_k127_2457387_0 Beta-eliminating lyase K01667 - 4.1.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006496 458.0
HFD2_k127_2457387_1 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000003913 178.0
HFD2_k127_2457387_2 Pfam:UPF0118 - - - 0.000000000000000004223 96.0
HFD2_k127_246633_1 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009477 248.0
HFD2_k127_2472506_0 sequestering of TGFbeta in extracellular matrix K17307 GO:0002009,GO:0002165,GO:0003674,GO:0005198,GO:0005201,GO:0005575,GO:0005576,GO:0007275,GO:0007424,GO:0007444,GO:0007472,GO:0007475,GO:0007476,GO:0007552,GO:0007560,GO:0007591,GO:0008150,GO:0008362,GO:0008587,GO:0009653,GO:0009791,GO:0009886,GO:0009887,GO:0009888,GO:0022404,GO:0031012,GO:0032501,GO:0032502,GO:0035107,GO:0035114,GO:0035120,GO:0035220,GO:0035239,GO:0035295,GO:0040003,GO:0040005,GO:0042303,GO:0042335,GO:0044421,GO:0044719,GO:0048513,GO:0048563,GO:0048569,GO:0048707,GO:0048729,GO:0048731,GO:0048736,GO:0048737,GO:0048856,GO:0060429,GO:0060541,GO:0060562,GO:0065007,GO:0065008,GO:0090066 - 0.00000000000001477 81.0
HFD2_k127_2472506_1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel K20628 - - 0.00000000000008201 81.0
HFD2_k127_2474593_0 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000689 554.0
HFD2_k127_2474593_2 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002136 258.0
HFD2_k127_2477806_0 FAD linked oxidases, C-terminal domain K00803 - 2.5.1.26 0.0000000000002908 72.0
HFD2_k127_2485004_0 Serine Threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000002487 203.0
HFD2_k127_2500258_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000531 229.0
HFD2_k127_2500258_1 Protein kinase domain - - - 0.00000000000000000000000000000000005069 141.0
HFD2_k127_2503081_0 Protein kinase domain K08884 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000004573 261.0
HFD2_k127_2503081_2 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000151 151.0
HFD2_k127_2503081_3 protein kinase activity - - - 0.0000000000000000000000008086 115.0
HFD2_k127_2503081_4 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000001885 104.0
HFD2_k127_2503081_5 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000001429 89.0
HFD2_k127_2506742_0 bacterial-type flagellum-dependent cell motility - - - 0.0000000000000000000000000000000000001586 162.0
HFD2_k127_2510803_0 - - - - 0.00000000000000000000000000002171 126.0
HFD2_k127_2511950_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009126 460.0
HFD2_k127_2511950_1 major pilin protein fima - - - 0.0000002636 56.0
HFD2_k127_251456_0 Aerotolerance regulator N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006626 543.0
HFD2_k127_251456_1 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 298.0
HFD2_k127_251456_2 Amidohydrolase family K05603 - 3.5.3.13 0.0000000000000000000000000000000000000000000000000000000000000000002805 234.0
HFD2_k127_2515524_0 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006311 348.0
HFD2_k127_2515524_1 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006778 329.0
HFD2_k127_2515524_2 Universal stress protein - - - 0.00000000000000000000000000000004524 133.0
HFD2_k127_2524257_0 Family membership K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000001205 181.0
HFD2_k127_2529017_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 379.0
HFD2_k127_2529017_1 Family membership K08884 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007209 394.0
HFD2_k127_2529017_2 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000002696 130.0
HFD2_k127_2534013_0 Aldo/keto reductase family - - - 0.000000000000000000000000009498 116.0
HFD2_k127_2534013_1 Belongs to the peptidase S1B family - - - 0.0000000000000000000000002554 119.0
HFD2_k127_2534908_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.542e-204 657.0
HFD2_k127_2534908_1 COG1073 hydrolases of the alpha beta superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001941 272.0
HFD2_k127_2534908_2 COG1073 hydrolases of the alpha beta superfamily - - - 0.0000000000000000000000000009188 115.0
HFD2_k127_2535114_0 fatty acid transporter K02106 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000001235 121.0
HFD2_k127_2542153_0 PFAM NB-ARC domain - - - 0.0005026 49.0
HFD2_k127_2556184_0 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000945 258.0
HFD2_k127_2556184_1 palmitoyl-(protein) hydrolase activity K06999 - - 0.0000000000000000000000000000000000000000000005699 178.0
HFD2_k127_255988_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006562 338.0
HFD2_k127_255988_1 Belongs to the glycosyl hydrolase 5 (cellulase A) family K05991 - 3.2.1.123 0.000000000000000000000000000000000000000000000000002761 198.0
HFD2_k127_255988_2 Protein conserved in bacteria - - - 0.0000000000002009 77.0
HFD2_k127_2560265_0 NCS1 nucleoside transporter - - - 0.00000000000000000000000000000000000000000000000000000000001076 212.0
HFD2_k127_2567425_0 short chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 587.0
HFD2_k127_2567425_1 - - - - 0.0000000000000001323 86.0
HFD2_k127_2567425_2 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000007023 66.0
HFD2_k127_2571124_0 DNA methylase K00571 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 378.0
HFD2_k127_2571124_1 - - - - 0.0000000000000000000000000000000002121 145.0
HFD2_k127_2571124_2 protein kinase activity - - - 0.0000000000000000000000993 101.0
HFD2_k127_2571124_3 Belongs to the HpcH HpaI aldolase family - - - 0.000000000000000001527 90.0
HFD2_k127_2583910_0 epimerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 318.0
HFD2_k127_2583910_1 Rossmann-like domain K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000001399 181.0
HFD2_k127_2583910_2 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 - - - 0.0000000000000000000000000000001179 130.0
HFD2_k127_2583910_3 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00001414 56.0
HFD2_k127_2584646_0 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000001258 237.0
HFD2_k127_2584646_1 Peptidyl-prolyl cis-trans K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000003134 153.0
HFD2_k127_2584646_2 Putative metal-binding motif - - - 0.0000000000000000000000000000002945 135.0
HFD2_k127_2589640_0 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 291.0
HFD2_k127_2589640_1 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000003144 241.0
HFD2_k127_2589640_2 Putative zinc-finger K03088 - - 0.000000001946 61.0
HFD2_k127_2600611_0 - - - - 0.00000000002228 74.0
HFD2_k127_2600611_1 Forkhead associated domain - - - 0.00005598 54.0
HFD2_k127_2601237_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 497.0
HFD2_k127_2601237_1 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009794 310.0
HFD2_k127_2601237_2 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000001006 205.0
HFD2_k127_2606039_0 abc transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 332.0
HFD2_k127_2606039_1 OmpA family K02557 - - 0.00000000000000000000000000000000000000000000000000000001092 208.0
HFD2_k127_2606039_2 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000614 205.0
HFD2_k127_2606039_3 COG3911 Predicted ATPase - - - 0.0000000003165 62.0
HFD2_k127_2609362_0 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 310.0
HFD2_k127_2611852_0 Uncharacterized conserved protein (COG2071) K09166 - - 0.000000000000000000000000000000000000000000000000000000003298 209.0
HFD2_k127_2611852_1 FCD - GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043207,GO:0043565,GO:0044403,GO:0044419,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0075136,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000002064 83.0
HFD2_k127_2615229_0 Family membership - - - 1.926e-276 895.0
HFD2_k127_2615229_1 Serine aminopeptidase, S33 - - - 0.000001171 54.0
HFD2_k127_2616424_0 serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004514 376.0
HFD2_k127_2616424_1 DNA-binding regulatory protein K03088 - - 0.00000000008842 69.0
HFD2_k127_2617518_0 ADP-ribosylglycohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004178 281.0
HFD2_k127_2617518_1 Esterase PHB depolymerase K03932 - - 0.000000000000000006565 88.0
HFD2_k127_2618881_0 Domain of unknown function (DUF3943) - - - 0.00000000000000000000000000000000000009883 161.0
HFD2_k127_2619365_0 Threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 385.0
HFD2_k127_2619365_1 GMC oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348 317.0
HFD2_k127_2619365_2 transcriptional - - - 0.000000000000000000000000000000001738 141.0
HFD2_k127_2619365_3 Tetratricopeptide repeat - - - 0.00000002667 63.0
HFD2_k127_2622559_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003832 556.0
HFD2_k127_2622559_1 two component, sigma54 specific, transcriptional regulator, Fis family K10941 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008673 353.0
HFD2_k127_2623590_0 seryl-tRNA synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 455.0
HFD2_k127_2623590_1 Domain of unknown function (DUF1839) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003881 400.0
HFD2_k127_2623590_2 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000134 277.0
HFD2_k127_2623590_3 Phosphopantetheine attachment site - - - 0.00000000000000000000000009263 108.0
HFD2_k127_2623590_4 holo-[acyl-carrier-protein] synthase activity K00997,K01207 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008897,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0018070,GO:0018193,GO:0018209,GO:0018215,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 2.7.8.7,3.2.1.52 0.0000000000000000009413 98.0
HFD2_k127_2626403_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000001845 203.0
HFD2_k127_2626403_1 Protein kinase domain K12132 - 2.7.11.1 0.0008312 51.0
HFD2_k127_2627718_0 serine threonine protein kinase K08884,K12132 - 2.7.11.1 2.406e-209 673.0
HFD2_k127_2627718_1 conserved protein (DUF2183) - - - 0.000000000000008051 76.0
HFD2_k127_2631824_0 WGR domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 329.0
HFD2_k127_2631824_1 DTW - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008193 246.0
HFD2_k127_2631824_2 RNA pseudouridylate synthase K06175 - 5.4.99.26 0.000000000000000000000000002974 113.0
HFD2_k127_2644010_0 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000004039 216.0
HFD2_k127_2644010_1 - - - - 0.0000000000000000000000000000001009 130.0
HFD2_k127_264522_0 PhoQ Sensor - - - 0.0000000000000000000000000000000008647 145.0
HFD2_k127_264522_1 Uncharacterized protein conserved in bacteria (DUF2334) K06986 - - 0.0000000000000000000000000007117 123.0
HFD2_k127_2647712_0 GHMP kinases N terminal domain K01597 - 4.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002081 286.0
HFD2_k127_2647712_1 mevalonate kinase K00869 - 2.7.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000004492 267.0
HFD2_k127_2647712_2 Polyprenyl synthetase K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000003713 209.0
HFD2_k127_2647712_3 mevalonate kinase activity K00869,K00938,K16190 - 2.7.1.36,2.7.1.43,2.7.4.2 0.00000000003594 75.0
HFD2_k127_2647943_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009047 485.0
HFD2_k127_2647943_1 COG0488 ATPase components of ABC transporters with duplicated ATPase domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001822 270.0
HFD2_k127_2647943_2 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005768 250.0
HFD2_k127_2652639_0 HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004431 297.0
HFD2_k127_2652639_1 Serine Threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000001343 209.0
HFD2_k127_2652639_2 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000000000000000001629 145.0
HFD2_k127_2652639_3 peptidyl-tyrosine sulfation - - - 0.000000000000000000000001704 113.0
HFD2_k127_2652639_5 Oxidoreductase NAD-binding domain - - - 0.000000000002046 78.0
HFD2_k127_2655591_0 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000008256 161.0
HFD2_k127_2655591_1 SnoaL-like polyketide cyclase - - - 0.000001008 61.0
HFD2_k127_2655591_2 SnoaL-like polyketide cyclase - - - 0.000007244 58.0
HFD2_k127_2656672_0 General secretion pathway protein C K02452 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 304.0
HFD2_k127_2656672_1 Type II and III secretion system protein K02453 - - 0.0000000000000000000000000000001125 132.0
HFD2_k127_2656954_0 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005322 289.0
HFD2_k127_2656954_1 Lytic polysaccharide mono-oxygenase, cellulose-degrading - - - 0.000000000000000000000000000000000000001316 157.0
HFD2_k127_2656954_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000195 84.0
HFD2_k127_2657339_0 PFAM Inward rectifier potassium channel K08715 - - 0.0000000000000000000000000000000000000000000000000000000000000000005536 238.0
HFD2_k127_2657339_1 beta-lactamase activity K07126 - - 0.00000002591 67.0
HFD2_k127_2657339_2 PBS lyase HEAT-like repeat - - - 0.000177 55.0
HFD2_k127_2658824_0 Domain of unknown function (DUF3459) K01236 - 3.2.1.141 2.243e-197 634.0
HFD2_k127_2658824_1 ADP-ribosylglycohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008802 261.0
HFD2_k127_2660614_0 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007907 346.0
HFD2_k127_2660614_1 Acyl-CoA dehydrogenase, middle domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001273 248.0
HFD2_k127_2660614_2 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000004629 87.0
HFD2_k127_2668444_0 electron transfer activity - - - 0.0000000000000000000000000000000000000005809 152.0
HFD2_k127_2668444_1 self proteolysis - - - 0.00000000000000000000000001369 120.0
HFD2_k127_2673606_0 Sugar ABC transporter permease K10109,K15770,K15771 - - 2.469e-211 680.0
HFD2_k127_2673606_1 Binding-protein-dependent transport system inner membrane component K10110,K15772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 350.0
HFD2_k127_2673606_2 protocatechuate 3,4-dioxygenase activity K03381 - 1.13.11.1 0.000000000000000000000000001429 123.0
HFD2_k127_2673606_3 Belongs to the ABC transporter superfamily K05816,K10112 - 3.6.3.20 0.00000000000000000000008827 102.0
HFD2_k127_2676482_0 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 383.0
HFD2_k127_2676482_1 SMART Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 384.0
HFD2_k127_2690212_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001132 282.0
HFD2_k127_2690212_1 Domain of unknown function (DUF2760) - - - 0.000000000000000000000000000000000000000000000000000000003008 214.0
HFD2_k127_2690212_2 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000005416 162.0
HFD2_k127_2690212_3 acylphosphatase activity K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000000000000000000000000000001895 139.0
HFD2_k127_2690212_4 MreB/Mbl protein - - - 0.000000000000000000000000000006721 123.0
HFD2_k127_2692245_0 Methionine synthase K00548 - 2.1.1.13 0.0 1011.0
HFD2_k127_2692989_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000944 268.0
HFD2_k127_2692989_1 Histidine kinase - - - 0.000000000000000000000000006602 113.0
HFD2_k127_269823_0 3-methyladenine DNA glycosylase - - - 0.0000000000000000000000000000001917 136.0
HFD2_k127_269823_1 Type III restriction enzyme, res subunit - - - 0.00000000000000000000002836 107.0
HFD2_k127_2702354_0 Belongs to the CinA family K03742,K03743 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 482.0
HFD2_k127_2702354_1 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006136 290.0
HFD2_k127_2702354_2 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000667 280.0
HFD2_k127_2702354_3 Zn peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000001846 234.0
HFD2_k127_2702354_4 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000005565 203.0
HFD2_k127_2702354_5 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000008451 203.0
HFD2_k127_2702354_6 PFAM Formylglycine-generating sulfatase enzyme K08884,K12132,K18912 - 1.14.99.50,2.7.11.1 0.0000000000000000000000000000000000000000000000000000008103 205.0
HFD2_k127_2702354_7 PFAM ABC transporter related K02003 - - 0.00000000000000000000000000001098 130.0
HFD2_k127_2703749_0 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008423 492.0
HFD2_k127_2718825_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 410.0
HFD2_k127_2718825_1 Carbamoyl-phosphate synthase L chain, ATP binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002284 265.0
HFD2_k127_2718825_2 PIN domain - - - 0.00000000000000000000000000000001793 131.0
HFD2_k127_2718825_3 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000005641 86.0
HFD2_k127_2720947_0 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000395 402.0
HFD2_k127_2721092_0 DoxX K15977 - - 0.0000000000000000000000000000000000000000000001165 172.0
HFD2_k127_2721092_1 amine dehydrogenase activity - - - 0.00000000000000005808 94.0
HFD2_k127_2723528_0 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000001075 218.0
HFD2_k127_2723528_1 Domain of unknown function (DUF697) - - - 0.0000001406 63.0
HFD2_k127_2732976_0 Esterase PHB depolymerase K03932 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002045 263.0
HFD2_k127_2732976_1 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000001366 205.0
HFD2_k127_2732976_2 - - - - 0.000000000000000000000000001342 116.0
HFD2_k127_273728_0 Cysteine-rich domain K00113 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 524.0
HFD2_k127_273728_1 Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.0000000000000000000000000000000000000000000000000000000000000000000000005485 247.0
HFD2_k127_273728_2 Belongs to the Fur family K09825,K22297 - - 0.000000000000000000000000000000000000000001461 161.0
HFD2_k127_273728_3 DnaJ molecular chaperone homology domain - - - 0.000000000000000000002646 104.0
HFD2_k127_2738433_0 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000004147 174.0
HFD2_k127_2738433_1 WGR domain protein - - - 0.000002203 57.0
HFD2_k127_2739974_0 Voltage gated chloride channel K03281 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 376.0
HFD2_k127_2739974_1 - - - - 0.00000000000000000000001172 116.0
HFD2_k127_2745891_0 Sel1-like repeats. K07126 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007409 542.0
HFD2_k127_2745891_1 Protein kinase domain - - - 0.0000000000000000000000000000000000000001444 166.0
HFD2_k127_2755185_0 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006637 252.0
HFD2_k127_2755185_1 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000008154 172.0
HFD2_k127_2755185_3 Neuropathy target K14676 GO:0001525,GO:0001568,GO:0001894,GO:0001895,GO:0001932,GO:0001933,GO:0001944,GO:0003008,GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0005886,GO:0006469,GO:0006629,GO:0006643,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0007272,GO:0007275,GO:0007399,GO:0007600,GO:0007606,GO:0007608,GO:0008104,GO:0008150,GO:0008152,GO:0008219,GO:0009056,GO:0009395,GO:0009653,GO:0009887,GO:0009892,GO:0009987,GO:0010563,GO:0010605,GO:0012501,GO:0012505,GO:0016020,GO:0016042,GO:0016043,GO:0016298,GO:0016787,GO:0016788,GO:0019220,GO:0019222,GO:0019637,GO:0019899,GO:0019900,GO:0019901,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0031984,GO:0032268,GO:0032269,GO:0032501,GO:0032502,GO:0033036,GO:0033673,GO:0034236,GO:0034349,GO:0034613,GO:0035239,GO:0035295,GO:0042175,GO:0042325,GO:0042326,GO:0042592,GO:0043086,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043549,GO:0044092,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0045494,GO:0045859,GO:0045936,GO:0046434,GO:0046470,GO:0046475,GO:0046486,GO:0046503,GO:0048513,GO:0048514,GO:0048519,GO:0048523,GO:0048646,GO:0048731,GO:0048856,GO:0048871,GO:0050789,GO:0050790,GO:0050794,GO:0050877,GO:0051018,GO:0051171,GO:0051172,GO:0051174,GO:0051179,GO:0051246,GO:0051248,GO:0051338,GO:0051348,GO:0051402,GO:0051641,GO:0052689,GO:0060249,GO:0060255,GO:0061024,GO:0065007,GO:0065008,GO:0065009,GO:0070727,GO:0070997,GO:0071704,GO:0071840,GO:0071900,GO:0071901,GO:0071944,GO:0072358,GO:0072359,GO:0072657,GO:0080090,GO:0097164,GO:0098827,GO:1901564,GO:1901575,GO:2000479,GO:2000480 3.1.1.5 0.0007468 52.0
HFD2_k127_2757943_0 Sigma-70, region 4 K03088 - - 0.00005759 54.0
HFD2_k127_2763696_0 GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000001794 211.0
HFD2_k127_2763696_1 GDSL-like Lipase/Acylhydrolase family - - - 0.0002752 52.0
HFD2_k127_2764251_0 von Willebrand factor type A domain - - - 4.433e-244 790.0
HFD2_k127_2764251_1 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004023 352.0
HFD2_k127_2767884_0 Alpha-amylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005887 510.0
HFD2_k127_2767884_1 maltodextrin transmembrane transporter activity K02024 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 355.0
HFD2_k127_2768515_0 Subtilase family - - - 0.000000001718 71.0
HFD2_k127_2768515_1 Lamin Tail Domain - - - 0.00004916 56.0
HFD2_k127_2773286_0 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 481.0
HFD2_k127_2773286_1 Protein of unknown function (DUF692) K09930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000033 294.0
HFD2_k127_2773286_2 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005275 291.0
HFD2_k127_2773286_3 Family membership K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000004482 278.0
HFD2_k127_2773286_5 Tetratricopeptide repeat - - - 0.00000000000000000000000000000024 142.0
HFD2_k127_2773286_6 Protein of unknown function (DUF692) K09930 - - 0.00000000000000007295 87.0
HFD2_k127_2773286_7 Bacterial regulatory proteins, tetR family - - - 0.0004005 46.0
HFD2_k127_2782777_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004782 552.0
HFD2_k127_2784575_0 protein conserved in cyanobacteria - - - 0.000000000000000000000000000000000000000000000000000001921 198.0
HFD2_k127_2784575_1 Family membership K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000002286 183.0
HFD2_k127_2784575_2 FR47-like protein - - - 0.00000000000000000000000000000000006086 146.0
HFD2_k127_2784575_3 ubiquinone biosynthetic process K18586 - - 0.0000000000000000000000000000003538 132.0
HFD2_k127_2784575_4 transcriptional regulator K09017,K22295 - - 0.0000000003294 63.0
HFD2_k127_2795685_0 Peptide methionine sulfoxide reductase K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 333.0
HFD2_k127_2795685_1 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000002416 248.0
HFD2_k127_2795685_2 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000001829 230.0
HFD2_k127_2795685_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000005591 109.0
HFD2_k127_2795685_4 Acetyltransferase (GNAT) domain K03817 - - 0.0000006161 56.0
HFD2_k127_279720_0 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009348 319.0
HFD2_k127_279720_1 Peptidyl-prolyl cis-trans K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000001369 145.0
HFD2_k127_2798727_0 COG0076 Glutamate decarboxylase and related PLP-dependent proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007365 316.0
HFD2_k127_2798727_1 endonuclease activity K07451 - - 0.000000000000000000001618 105.0
HFD2_k127_2803549_0 8-amino-7-oxononanoate synthase activity K00639,K00652 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.3.1.29,2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006837 278.0
HFD2_k127_2803549_1 C-type lectin (CTL) or carbohydrate-recognition domain (CRD) K06563,K06721,K06795,K10057,K10058,K10059,K10060,K17513,K17514,K22244 GO:0001618,GO:0001775,GO:0001817,GO:0001818,GO:0001819,GO:0001871,GO:0001872,GO:0001878,GO:0001879,GO:0002218,GO:0002220,GO:0002223,GO:0002252,GO:0002253,GO:0002263,GO:0002285,GO:0002286,GO:0002292,GO:0002366,GO:0002376,GO:0002429,GO:0002468,GO:0002470,GO:0002474,GO:0002478,GO:0002520,GO:0002521,GO:0002682,GO:0002684,GO:0002694,GO:0002696,GO:0002757,GO:0002758,GO:0002764,GO:0002768,GO:0002791,GO:0002793,GO:0003674,GO:0003823,GO:0004888,GO:0005488,GO:0005509,GO:0005515,GO:0005537,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005887,GO:0006810,GO:0006897,GO:0006909,GO:0006910,GO:0006950,GO:0006952,GO:0006955,GO:0007154,GO:0007155,GO:0007157,GO:0007159,GO:0007165,GO:0007166,GO:0007275,GO:0008037,GO:0008150,GO:0008284,GO:0009595,GO:0009605,GO:0009607,GO:0009617,GO:0009620,GO:0009889,GO:0009891,GO:0009893,GO:0009897,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0009988,GO:0010556,GO:0010557,GO:0010604,GO:0010646,GO:0010647,GO:0015833,GO:0016020,GO:0016021,GO:0016032,GO:0016045,GO:0016046,GO:0016192,GO:0019048,GO:0019058,GO:0019062,GO:0019079,GO:0019222,GO:0019882,GO:0019884,GO:0022407,GO:0022409,GO:0022610,GO:0023051,GO:0023052,GO:0023056,GO:0030097,GO:0030098,GO:0030100,GO:0030154,GO:0030155,GO:0030217,GO:0030246,GO:0030247,GO:0030260,GO:0030369,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031347,GO:0031349,GO:0032501,GO:0032502,GO:0032680,GO:0032720,GO:0032760,GO:0032879,GO:0032880,GO:0032944,GO:0032946,GO:0033218,GO:0035556,GO:0035821,GO:0036037,GO:0036094,GO:0038023,GO:0038093,GO:0038094,GO:0042035,GO:0042102,GO:0042108,GO:0042110,GO:0042127,GO:0042129,GO:0042277,GO:0042534,GO:0042535,GO:0042590,GO:0042605,GO:0042742,GO:0042802,GO:0042803,GO:0042886,GO:0043122,GO:0043123,GO:0043167,GO:0043169,GO:0043207,GO:0044003,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044650,GO:0044766,GO:0045087,GO:0045088,GO:0045089,GO:0045321,GO:0045785,GO:0045807,GO:0046631,GO:0046649,GO:0046718,GO:0046790,GO:0046794,GO:0046872,GO:0046968,GO:0046983,GO:0048002,GO:0048029,GO:0048306,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048534,GO:0048583,GO:0048584,GO:0048731,GO:0048856,GO:0048869,GO:0050670,GO:0050671,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050764,GO:0050766,GO:0050776,GO:0050778,GO:0050789,GO:0050794,GO:0050832,GO:0050863,GO:0050865,GO:0050867,GO:0050870,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051240,GO:0051241,GO:0051246,GO:0051247,GO:0051249,GO:0051251,GO:0051606,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051806,GO:0051817,GO:0051828,GO:0060089,GO:0060255,GO:0060627,GO:0065007,GO:0070201,GO:0070663,GO:0070665,GO:0071702,GO:0071705,GO:0071944,GO:0075733,GO:0080090,GO:0080134,GO:0090087,GO:0097323,GO:0097367,GO:0098542,GO:0098543,GO:0098552,GO:0098581,GO:0098609,GO:0098657,GO:0098742,GO:0104005,GO:1902531,GO:1902533,GO:1902579,GO:1903037,GO:1903039,GO:1903530,GO:1903532,GO:1903555,GO:1903556,GO:1903557,GO:1904951 - 0.0000003276 59.0
HFD2_k127_2807585_0 fatty acid desaturase K00508 - 1.14.19.3 0.0000000000000000000000000000000000000000000000000000000004257 216.0
HFD2_k127_280961_0 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 317.0
HFD2_k127_280961_2 - - - - 0.00000000000000000000000000000000000000000000000000008549 198.0
HFD2_k127_280961_3 TIGRFAM sugar-phosphate isomerase, RpiB LacA LacB family K01808 - 5.3.1.6 0.000000000000000000000000000000000000007634 149.0
HFD2_k127_280961_4 DoxX-like family - - - 0.000000000000000000000000000000000247 138.0
HFD2_k127_280961_5 Globin - - - 0.0003797 46.0
HFD2_k127_2811085_1 Domain of unknown function (DUF4132) - - - 0.000000000000000000000000000000000000000000000000001679 207.0
HFD2_k127_2811085_2 ATPase involved in DNA repair - - - 0.000000000000000000000000000000000000000004548 168.0
HFD2_k127_2811085_3 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000001464 143.0
HFD2_k127_2811085_4 Peptidoglycan-binding domain 1 protein - - - 0.00000000000000000000000000003972 130.0
HFD2_k127_2813617_0 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000003712 156.0
HFD2_k127_2813617_1 Family membership K08884,K12132 - 2.7.11.1 0.000002867 58.0
HFD2_k127_2818504_0 Protein kinase domain K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003097 276.0
HFD2_k127_2818504_1 Domain of unknown function (DUF4419) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001803 252.0
HFD2_k127_2818504_2 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000002313 229.0
HFD2_k127_2823165_0 Low-density lipoprotein receptor domain class A - - - 0.000000001607 69.0
HFD2_k127_2823165_1 cellulose binding - - - 0.00054 51.0
HFD2_k127_2824292_0 TonB dependent receptor K02014,K16092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004119 263.0
HFD2_k127_2833319_0 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000327 137.0
HFD2_k127_2833319_1 Trypsin-like serine protease - GO:0005575,GO:0005576 - 0.0001863 52.0
HFD2_k127_2836287_0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal K00648,K22317 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 375.0
HFD2_k127_2836287_1 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000001425 241.0
HFD2_k127_2836287_2 synthase III K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000009573 182.0
HFD2_k127_2836287_3 Transglycosylase associated protein - - - 0.000000000000000001724 91.0
HFD2_k127_2844975_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 433.0
HFD2_k127_2844975_1 oxidoreductase activity K07114 - - 0.0000000000000000000000000000000000000000000000141 186.0
HFD2_k127_2844975_2 Sulfatase-modifying factor enzyme 1 K12132 - 2.7.11.1 0.000000000000000000000000000000000003911 158.0
HFD2_k127_2844975_3 SMART Glycoside hydrolase, family 10 K01181 - 3.2.1.8 0.0003229 52.0
HFD2_k127_2846205_0 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 364.0
HFD2_k127_2846205_1 Zinc metalloprotease (Elastase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000007045 250.0
HFD2_k127_2846205_2 Putative peptidoglycan binding domain - - - 0.00000000000000000000000000000000000000000001789 169.0
HFD2_k127_2846205_3 ABC-2 family transporter protein - - - 0.00000000000000000000000002295 119.0
HFD2_k127_2853439_0 Belongs to the UPF0229 family K09786 - - 2.979e-206 646.0
HFD2_k127_2853439_1 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003719 462.0
HFD2_k127_2853439_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 332.0
HFD2_k127_2853450_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000002912 233.0
HFD2_k127_2853450_2 Lipase (class 2) - - - 0.000000558 61.0
HFD2_k127_2869730_0 - - - - 0.00000000005875 73.0
HFD2_k127_2872989_0 oxidoreductase activity K07114 - - 0.0000000000000000000000329 113.0
HFD2_k127_2873509_0 e3 binding domain K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 392.0
HFD2_k127_2873509_1 Transketolase, pyrimidine binding domain K00162,K21417 - 1.2.4.1 0.00000000000000000000001128 101.0
HFD2_k127_2873509_2 Phosphopantetheine attachment site - - - 0.00000000000000009862 89.0
HFD2_k127_2879034_0 cytochrome C peroxidase - - - 0.000000000000000000000000000000000000000005309 166.0
HFD2_k127_2882711_0 Transglycosylase K05367 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000001696 241.0
HFD2_k127_2882711_1 WGR domain protein - - - 0.00005484 55.0
HFD2_k127_2883473_0 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000002227 165.0
HFD2_k127_2883473_1 transposase activity - - - 0.000008327 50.0
HFD2_k127_2883473_2 beta-lactamase activity K07126 - - 0.0004293 44.0
HFD2_k127_2889870_0 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 316.0
HFD2_k127_2889870_1 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000000006369 212.0
HFD2_k127_2889870_2 HlyD family secretion protein K02005 - - 0.000000000000000000000000000000000003691 155.0
HFD2_k127_2889870_3 Barrel-sandwich domain of CusB or HlyD membrane-fusion K03585 - - 0.0000000001874 73.0
HFD2_k127_2893155_0 PAS fold - - - 0.0000000000000000000000006239 108.0
HFD2_k127_2896638_0 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001121 272.0
HFD2_k127_2896638_1 - - - - 0.0000000000000000000000000000000000000000000000007864 186.0
HFD2_k127_2911229_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0000000000000000000000000000000000000000000000000000000000000003035 241.0
HFD2_k127_2911229_1 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000001071 214.0
HFD2_k127_2911310_0 COG0326 Molecular chaperone, HSP90 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001787 299.0
HFD2_k127_2914838_0 ABC transporter K01990 - - 0.00000005009 65.0
HFD2_k127_2915483_1 Caspase domain - - - 0.0001549 52.0
HFD2_k127_2915789_0 Domain of unknown function (DUF4175) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 400.0
HFD2_k127_2915789_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 357.0
HFD2_k127_2915789_2 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 334.0
HFD2_k127_2915789_3 Domain of unknown function (DUF4175) - - - 0.0000000000000000000000000000000000000000000000000000000000008588 230.0
HFD2_k127_2916490_0 to choline dehydrogenase K00108 - 1.1.99.1 3.131e-238 756.0
HFD2_k127_2916490_1 - - - - 0.0000000000000000000001077 109.0
HFD2_k127_2916490_2 bacterial-type flagellum-dependent cell motility - - - 0.00004621 50.0
HFD2_k127_292323_0 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K03594,K03921,K07052 - 1.14.19.11,1.14.19.2,1.14.19.26,1.16.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002879 280.0
HFD2_k127_292323_1 - - - - 0.00000046 61.0
HFD2_k127_2924470_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000733 290.0
HFD2_k127_2924470_1 Family membership K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000006426 258.0
HFD2_k127_2928023_0 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 344.0
HFD2_k127_2928023_1 protein targeting - - - 0.0009311 51.0
HFD2_k127_2929204_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008568 454.0
HFD2_k127_2942566_0 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 384.0
HFD2_k127_2942566_1 COG1121 ABC-type Mn Zn transport systems ATPase component K09817 - - 0.0000000000000000000000000000000000004104 147.0
HFD2_k127_2944532_0 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000001279 190.0
HFD2_k127_2944532_1 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000004599 182.0
HFD2_k127_2947614_1 Trypsin-like serine protease - - - 0.00000008272 60.0
HFD2_k127_2948315_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000021 288.0
HFD2_k127_2948315_1 Response regulator, receiver - - - 0.00000000000000000000000004721 124.0
HFD2_k127_2948315_2 - - - - 0.00000000001864 78.0
HFD2_k127_2949234_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 1.495e-226 716.0
HFD2_k127_2949234_1 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000415 267.0
HFD2_k127_2949234_2 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000004418 242.0
HFD2_k127_2949234_3 - - - - 0.00000000000000000000000000894 121.0
HFD2_k127_2949442_0 ABC transporter K06861 - - 0.000000000000000000000000000000000000000003183 165.0
HFD2_k127_2949442_1 Protein conserved in bacteria K09774 - - 0.00000446 57.0
HFD2_k127_2955189_0 Short chain dehydrogenase - - - 0.00000000000000000000000001603 123.0
HFD2_k127_2958386_0 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 353.0
HFD2_k127_2960551_0 NAD dependent epimerase/dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 433.0
HFD2_k127_2960551_1 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000001474 161.0
HFD2_k127_2967102_0 Zinc-binding dehydrogenase K00001 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0007275,GO:0007399,GO:0008150,GO:0009987,GO:0010975,GO:0016020,GO:0019867,GO:0022008,GO:0030154,GO:0031090,GO:0031344,GO:0031966,GO:0031967,GO:0031968,GO:0031975,GO:0032501,GO:0032502,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045595,GO:0045664,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050767,GO:0050773,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051239,GO:0051960,GO:0060284,GO:0065007,GO:0098588,GO:0098805,GO:0120035,GO:2000026 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009331 350.0
HFD2_k127_2968564_0 oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005329 267.0
HFD2_k127_2968564_1 Gluconate 2-dehydrogenase subunit 3 K06152 - 1.1.99.3 0.0000000002586 71.0
HFD2_k127_2975030_0 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 550.0
HFD2_k127_2975030_1 AAA ATPase domain - - - 0.000000000000000009377 91.0
HFD2_k127_2975355_0 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001505 282.0
HFD2_k127_2975355_1 Polysaccharide deacetylase K22278 - 3.5.1.104 0.000000000000000000000268 108.0
HFD2_k127_2977839_0 Associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004835 525.0
HFD2_k127_2977839_1 protein containing a von Willebrand factor type A (vWA) domain - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000006355 226.0
HFD2_k127_2977839_2 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000001921 132.0
HFD2_k127_2978987_0 PFAM sigma-54 factor interaction domain-containing protein K07715 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 361.0
HFD2_k127_2978987_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000562 63.0
HFD2_k127_2980944_0 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000003551 187.0
HFD2_k127_2980944_1 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.00000000000000000000000000000003896 142.0
HFD2_k127_2980944_2 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.000000000005627 69.0
HFD2_k127_2994017_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002944 373.0
HFD2_k127_3009713_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 304.0
HFD2_k127_3009713_1 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000003241 186.0
HFD2_k127_3010363_0 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K07712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 389.0
HFD2_k127_3010363_2 von Willebrand factor type A domain - - - 0.00000000000000000000000000000000000002896 155.0
HFD2_k127_3010363_3 Domain of unknown function (DUF362) - - - 0.00000003307 55.0
HFD2_k127_3016122_0 Involved in the tonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005187 322.0
HFD2_k127_3016980_0 Thermolysin metallopeptidase, alpha-helical domain K01400,K08777 GO:0005575,GO:0005576 3.4.24.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008487 291.0
HFD2_k127_3020302_1 Ankyrin repeat - - - 0.00000000000007208 83.0
HFD2_k127_3023539_0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009323 362.0
HFD2_k127_3023539_1 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000471 234.0
HFD2_k127_3027960_0 Beta propeller domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007224 330.0
HFD2_k127_3032279_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 432.0
HFD2_k127_3032279_1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000006399 228.0
HFD2_k127_3033423_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00322 - 1.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005537 516.0
HFD2_k127_3033423_1 EB module - - - 0.00000000236 69.0
HFD2_k127_3043648_0 COG1063 Threonine dehydrogenase and related Zn-dependent - - - 0.000000000000000000000000000000000000000000000000001558 193.0
HFD2_k127_3043648_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source - - - 0.000000000000000000000000000000000000000000000001677 190.0
HFD2_k127_3057497_0 deaminase K01493 - 3.5.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000109 251.0
HFD2_k127_3057497_1 Belongs to the D-alanine--D-alanine ligase family K01921 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008716,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.4 0.00000000000000000000000005545 115.0
HFD2_k127_3060740_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009913 490.0
HFD2_k127_3060740_1 phosphoprotein phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000007778 218.0
HFD2_k127_3060740_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000001247 197.0
HFD2_k127_3064156_0 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006796 567.0
HFD2_k127_3064156_2 Calcium ion binding - GO:0002009,GO:0002165,GO:0003674,GO:0005198,GO:0005201,GO:0005575,GO:0005576,GO:0007275,GO:0007424,GO:0007444,GO:0007472,GO:0007475,GO:0007476,GO:0007552,GO:0007560,GO:0007591,GO:0008150,GO:0008362,GO:0008587,GO:0009653,GO:0009791,GO:0009886,GO:0009887,GO:0009888,GO:0022404,GO:0031012,GO:0032501,GO:0032502,GO:0035107,GO:0035114,GO:0035120,GO:0035220,GO:0035239,GO:0035295,GO:0040003,GO:0040005,GO:0042303,GO:0042335,GO:0044421,GO:0044719,GO:0048513,GO:0048563,GO:0048569,GO:0048707,GO:0048729,GO:0048731,GO:0048736,GO:0048737,GO:0048856,GO:0060429,GO:0060541,GO:0060562,GO:0065007,GO:0065008,GO:0090066 - 0.0000000221 64.0
HFD2_k127_3064534_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009444 308.0
HFD2_k127_3064534_1 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000002052 188.0
HFD2_k127_3068651_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000000000000000000000000000005395 167.0
HFD2_k127_3068651_1 Transglycosylase associated protein - - - 0.000000000000000001274 95.0
HFD2_k127_3068651_2 Belongs to the 5'-nucleotidase family K01081 - 3.1.3.5 0.00000000000002105 76.0
HFD2_k127_3072188_0 Calcium-binding EGF domain - - - 0.000000009231 68.0
HFD2_k127_3073625_0 Protein of unknown function (DUF3570) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 349.0
HFD2_k127_3080439_0 Acyl-CoA thioesterase K10805 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 392.0
HFD2_k127_3080439_1 Trypsin-like serine protease - - - 0.0005655 50.0
HFD2_k127_3080663_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008284 306.0
HFD2_k127_3080663_1 AAA ATPase domain K01768 - 4.6.1.1 0.00000000000000000000000000007718 132.0
HFD2_k127_3080663_2 adenosine deaminase K01488 - 3.5.4.4 0.000000003205 60.0
HFD2_k127_3084373_0 Domain of unknown function (DUF4105) - - - 0.0000000000000000000000000000004042 137.0
HFD2_k127_3087365_0 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006191 268.0
HFD2_k127_3087365_1 cell envelope organization K05807,K08309 - - 0.00000000000001245 81.0
HFD2_k127_309141_0 Belongs to the glycosyl hydrolase family 6 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 487.0
HFD2_k127_309141_1 Copper binding periplasmic protein CusF K07152 - - 0.0001601 48.0
HFD2_k127_3095852_0 phosphorelay signal transduction system K01768,K10941,K11894 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007559 458.0
HFD2_k127_3095852_1 Zinc metalloprotease (Elastase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 376.0
HFD2_k127_3095852_2 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000000001247 181.0
HFD2_k127_3099027_0 - - - - 0.00000000000000000000000000000000000000000000000000183 202.0
HFD2_k127_3099027_1 peptidyl-tyrosine sulfation - - - 0.00000000002693 76.0
HFD2_k127_3101574_0 HTH domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004745 304.0
HFD2_k127_3101574_1 Vault protein inter-alpha-trypsin domain - - - 0.0000000000000000000000000000000000000000000000000004328 199.0
HFD2_k127_3101574_2 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000008326 174.0
HFD2_k127_3115640_0 Cys Met metabolism K01739,K01758,K01760,K01761 - 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007909 488.0
HFD2_k127_3115640_1 helix_turn_helix, Lux Regulon - - - 0.000000000003529 72.0
HFD2_k127_3120682_0 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309,K11102 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 556.0
HFD2_k127_3120682_1 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003648 494.0
HFD2_k127_3120682_2 Beta propeller domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 508.0
HFD2_k127_3120682_3 PFAM FAD linked oxidase domain protein K00803 - 2.5.1.26 0.0000000000000000000000000000000000000000000000000000000000001665 217.0
HFD2_k127_3120682_4 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000004846 161.0
HFD2_k127_3120682_5 Glucose / Sorbosone dehydrogenase - - - 0.000000001013 68.0
HFD2_k127_3120682_6 Bacterial regulatory proteins, tetR family - - - 0.000000001348 69.0
HFD2_k127_3120682_7 extracellular matrix structural constituent - - - 0.00000002022 66.0
HFD2_k127_3123868_0 protein N-acetylglucosaminyltransferase activity - - - 0.0000000000002815 84.0
HFD2_k127_3123868_1 - - - - 0.000000000002846 79.0
HFD2_k127_3126433_0 TonB dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008766 385.0
HFD2_k127_3126433_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000001741 105.0
HFD2_k127_3135615_0 ADP-ribosylglycohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 376.0
HFD2_k127_3135615_1 - - - - 0.000000000000000000000000000000000000000000000000000004513 202.0
HFD2_k127_3135615_2 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 - 2.1.1.257 0.0000000000000000000000000000000000000134 153.0
HFD2_k127_3142554_0 Aldo Keto reductase - - - 0.000000000000000000000000000000000000000000000006232 179.0
HFD2_k127_3142554_2 SnoaL-like polyketide cyclase K06893 - - 0.000000000005573 78.0
HFD2_k127_3142554_3 SnoaL-like polyketide cyclase - - - 0.00000003659 65.0
HFD2_k127_3143744_0 Zn-dependent proteases and their inactivated homologs K03592 - - 2.875e-194 616.0
HFD2_k127_3143744_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000002634 170.0
HFD2_k127_3143744_2 sequence-specific DNA binding K07726 - - 0.0000000000000000000000000000002212 129.0
HFD2_k127_3144230_0 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 472.0
HFD2_k127_3144230_1 Biopolymer transport protein ExbD/TolR - - - 0.00004564 57.0
HFD2_k127_3147294_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002443 284.0
HFD2_k127_3147294_1 PEGA domain - - - 0.000000000000000000000000009848 123.0
HFD2_k127_3147294_2 negative regulation of mitochondrial membrane permeability involved in apoptotic process K07508,K17972 GO:0001666,GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006066,GO:0006082,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006635,GO:0006637,GO:0006694,GO:0006695,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006839,GO:0006915,GO:0006950,GO:0006996,GO:0007005,GO:0007006,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008219,GO:0008610,GO:0008637,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009628,GO:0009966,GO:0009968,GO:0009987,GO:0010639,GO:0010646,GO:0010648,GO:0010821,GO:0010823,GO:0010941,GO:0012501,GO:0016042,GO:0016043,GO:0016054,GO:0016125,GO:0016126,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019637,GO:0019693,GO:0019752,GO:0023051,GO:0023057,GO:0030258,GO:0031974,GO:0032787,GO:0032879,GO:0033043,GO:0033554,GO:0033865,GO:0033875,GO:0034032,GO:0034440,GO:0034641,GO:0035383,GO:0035795,GO:0036293,GO:0036294,GO:0042221,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046165,GO:0046395,GO:0046483,GO:0046902,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051129,GO:0051179,GO:0051186,GO:0051234,GO:0051716,GO:0055086,GO:0055114,GO:0060548,GO:0061024,GO:0065007,GO:0065008,GO:0070013,GO:0070482,GO:0070887,GO:0071453,GO:0071456,GO:0071704,GO:0071840,GO:0072329,GO:0072521,GO:0090559,GO:1901028,GO:1901029,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901617,GO:1902108,GO:1902109,GO:1902652,GO:1902653,GO:1905709,GO:2001233,GO:2001234 2.3.1.16,2.3.1.254 0.0000000000000000000000219 99.0
HFD2_k127_3147306_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 316.0
HFD2_k127_3147306_2 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589,K13052 - - 0.0000000000000000000004438 101.0
HFD2_k127_3164443_0 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000005854 213.0
HFD2_k127_3164443_1 PEGA domain - - - 0.0000000000000000000000000000000000000000000000000001191 201.0
HFD2_k127_3164443_2 Glycosyl transferase family 1 - - - 0.000000000000000000000000000000000000000000000000007698 182.0
HFD2_k127_3164443_3 PFAM Formylglycine-generating sulfatase enzyme K12132 - 2.7.11.1 0.0002377 46.0
HFD2_k127_316617_0 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004757 461.0
HFD2_k127_316617_1 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008754 409.0
HFD2_k127_316617_2 Belongs to the peptidase S8 family K12287 - - 0.0000000000000000000001585 109.0
HFD2_k127_3176292_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000006002 130.0
HFD2_k127_3176292_2 Zinc finger LSD1 subclass family protein K08654 - - 0.0000000000000006566 91.0
HFD2_k127_3176292_3 Polysaccharide deacetylase K22278 - 3.5.1.104 0.0000000002723 73.0
HFD2_k127_3191709_0 Family membership K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002071 277.0
HFD2_k127_3191826_0 PGAP1-like protein - - - 0.00000000000000000000000000000000000000000004372 165.0
HFD2_k127_3191826_1 Protein of unknown function (DUF2867) - - - 0.00000000000000000000000001048 117.0
HFD2_k127_3191826_2 - - - - 0.000000000000007811 79.0
HFD2_k127_3193082_0 Esterase PHB depolymerase K03932 - - 0.0000000000001315 83.0
HFD2_k127_3194040_0 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000339 146.0
HFD2_k127_319772_0 glutathionylspermidine amidase activity K01460 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008884,GO:0008885,GO:0016787,GO:0016810,GO:0016811,GO:0016874,GO:0016879,GO:0016880,GO:0044424,GO:0044444,GO:0044464 3.5.1.78,6.3.1.8 0.0000000000000001049 94.0
HFD2_k127_319772_2 cell wall binding repeat 2 - - - 0.00000001516 67.0
HFD2_k127_3202125_0 Protein of unknown function (DUF434) - - - 0.00000000000000000001055 100.0
HFD2_k127_3202125_1 Transposase IS200 like - - - 0.0000001996 56.0
HFD2_k127_3203494_0 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004573 320.0
HFD2_k127_3203494_1 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000001921 199.0
HFD2_k127_3203494_2 - - - - 0.000000000000000000000000000000000000000000000005112 177.0
HFD2_k127_3203494_3 helix_turn_helix, Arsenical Resistance Operon Repressor K21903 - - 0.000000000000000000000000292 109.0
HFD2_k127_3207406_0 TonB dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 343.0
HFD2_k127_3207406_1 Glycosyl hydrolases family 31 K01187 - 3.2.1.20 0.000000000003744 79.0
HFD2_k127_3207494_0 Protein of unknown function (DUF3494) K11904 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000117 259.0
HFD2_k127_3211955_0 Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate K00451 - 1.13.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 385.0
HFD2_k127_3211955_1 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000201 259.0
HFD2_k127_3212271_0 GMC oxidoreductase K03333 - 1.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000001449 247.0
HFD2_k127_3212271_1 Protein phosphatase 2A homologues, catalytic domain. - - - 0.000000000000000000000000000000501 127.0
HFD2_k127_3215738_1 peptidyl-prolyl cis-trans isomerase activity K02597,K03769,K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000205 213.0
HFD2_k127_3215738_2 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000000000000000000000000000000000000000000000000000000003215 209.0
HFD2_k127_3215738_4 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000001014 103.0
HFD2_k127_3217050_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 502.0
HFD2_k127_3217711_0 MBOAT, membrane-bound O-acyltransferase family K19294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 500.0
HFD2_k127_3217711_1 COG2755 Lysophospholipase L1 and related esterases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 352.0
HFD2_k127_3217711_2 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000000000000000000000000000000000000000000000001077 213.0
HFD2_k127_3223028_0 phospholipase C - - - 0.00000000000000000000000000000000000000000000001926 181.0
HFD2_k127_3223028_1 Beta propeller domain - - - 0.0005702 51.0
HFD2_k127_3228283_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000004919 226.0
HFD2_k127_3228283_1 Outer membrane efflux protein - - - 0.0000000000000000000000000000007995 130.0
HFD2_k127_3229416_1 serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.00000000000000000000000001646 120.0
HFD2_k127_3229416_2 Domain of unknown function (DUF4388) - - - 0.00001961 57.0
HFD2_k127_3229516_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 449.0
HFD2_k127_3229516_1 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006702 295.0
HFD2_k127_3229516_3 Family membership K08884,K12132 - 2.7.11.1 0.00000001596 67.0
HFD2_k127_3231477_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 599.0
HFD2_k127_3231477_1 zinc-ribbon family - - - 0.000000000000000000000000000000000000000000000000000000000002247 215.0
HFD2_k127_3231477_2 iron ion homeostasis - - - 0.000000000000000000000000000000000000000000000000007037 199.0
HFD2_k127_3231477_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000002869 171.0
HFD2_k127_3231477_4 PFAM Isoprenylcysteine carboxyl methyltransferase K00587 - 2.1.1.100 0.0000000000109 76.0
HFD2_k127_3236635_0 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009287 385.0
HFD2_k127_3236715_0 protein trimerization K06894,K07114 - - 0.000000000000000000000000000000000000000007313 172.0
HFD2_k127_3236715_1 - - - - 0.00000000000000000000000000000000000009681 151.0
HFD2_k127_3242753_0 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000001461 196.0
HFD2_k127_3245819_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 329.0
HFD2_k127_3245819_1 PFAM Short-chain dehydrogenase reductase SDR K00059,K03366 - 1.1.1.100,1.1.1.304,1.1.1.76 0.00000000000000000000000000000000002998 144.0
HFD2_k127_3245819_2 Nitroreductase family K04719 - 1.13.11.79 0.000000000000000000000000005401 124.0
HFD2_k127_3245819_4 efflux transmembrane transporter activity K02004 - - 0.00000156 60.0
HFD2_k127_3248782_0 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007816 471.0
HFD2_k127_3248782_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008198 336.0
HFD2_k127_3248782_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009218 274.0
HFD2_k127_3251752_0 Transmembrane protein of unknown function (DUF3556) - - - 2.335e-215 681.0
HFD2_k127_3264468_0 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007512 381.0
HFD2_k127_3264468_1 Helix-turn-helix domain K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 349.0
HFD2_k127_3264468_2 Periplasmic binding protein K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000408 241.0
HFD2_k127_3264733_0 aldo keto reductase K05275 - 1.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 378.0
HFD2_k127_3264733_1 Pfam Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000000000002183 192.0
HFD2_k127_3264733_2 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000001966 169.0
HFD2_k127_3264733_3 Family membership K08884 - 2.7.11.1 0.000000000000000000000000000000000000104 147.0
HFD2_k127_3271183_0 PhoD-like phosphatase, N-terminal domain K01113 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005857 449.0
HFD2_k127_3271183_1 transmembrane transport K03442,K22044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009364 394.0
HFD2_k127_3271183_2 glutathione-regulated potassium exporter activity - - - 0.0000000000000001471 81.0
HFD2_k127_3277693_0 Belongs to the glycosyl hydrolase 18 family - - - 0.0000000000000000000000000000000000000000000000000001583 199.0
HFD2_k127_3277693_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.000000000000000000000000000000000000000000000001165 180.0
HFD2_k127_3277693_2 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000002303 109.0
HFD2_k127_3280392_0 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000001418 207.0
HFD2_k127_3280643_0 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0001465 48.0
HFD2_k127_3285552_0 TIGRFAM amino acid adenylation domain - - - 2.414e-245 797.0
HFD2_k127_3294943_0 glutathione transferase activity K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000001314 257.0
HFD2_k127_3295397_0 von Willebrand factor type A domain - - - 0.00000000000008347 80.0
HFD2_k127_3298760_0 GMC oxidoreductase K03333 - 1.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 532.0
HFD2_k127_3298760_1 PFAM Serine threonine-protein kinase-like domain - - - 0.0004185 44.0
HFD2_k127_3299131_0 Oligonucleotide/oligosaccharide-binding (OB)-fold K03578,K03579 - 3.6.4.13 0.0 1244.0
HFD2_k127_3299131_1 AAA domain - - - 0.00000000000000000000000000000000000000000000000009369 204.0
HFD2_k127_3299131_2 Polymer-forming cytoskeletal - - - 0.00000958 53.0
HFD2_k127_3300097_0 regulation of response to stimulus K13730 - - 0.0000000000000000000000000000000000000000000000000000005538 198.0
HFD2_k127_3300097_1 PFAM WD domain, G-beta repeat - - - 0.000000000000000000000000000000002398 143.0
HFD2_k127_3301336_0 Carboxyl transferase domain - - - 2.398e-255 796.0
HFD2_k127_3301336_1 Family membership K08884 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000004288 235.0
HFD2_k127_3304763_0 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000001295 260.0
HFD2_k127_3304763_1 LysM domain - - - 0.0000000000000000000000000000000000000000244 158.0
HFD2_k127_3306766_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 1.758e-320 1011.0
HFD2_k127_3306766_1 Glutamate synthase, NADH NADPH, small subunit K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004834 274.0
HFD2_k127_3311349_0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001763 282.0
HFD2_k127_3311349_1 Sulfatase K01133 - 3.1.6.6 0.0000000000000000000000000000000000000000000000000001143 192.0
HFD2_k127_3312383_0 Histone methylation protein DOT1 - - - 0.000000000000000000000000007026 116.0
HFD2_k127_3312383_1 WGR domain protein - - - 0.0000000000000000000000004823 114.0
HFD2_k127_3315240_0 Aconitase C-terminal domain K01703 - 4.2.1.33,4.2.1.35 1.197e-214 673.0
HFD2_k127_3315240_1 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004785 286.0
HFD2_k127_3315240_2 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000004322 202.0
HFD2_k127_3315240_3 SPFH domain / Band 7 family - - - 0.0000000000000000000000000000000007285 133.0
HFD2_k127_3317571_0 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005803 297.0
HFD2_k127_3317571_1 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005854 269.0
HFD2_k127_3317571_2 PFAM PKD domain containing protein - - - 0.000000000000000000000000009873 125.0
HFD2_k127_3317571_3 translation initiation factor activity K06996 - - 0.000000002953 64.0
HFD2_k127_3317987_0 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003598 336.0
HFD2_k127_3317987_1 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000007807 205.0
HFD2_k127_3317987_2 peptidyl-tyrosine sulfation - - - 0.000000000000000001973 97.0
HFD2_k127_3318762_0 WGR domain protein - - - 0.000000000000000000000000000000000000000000883 160.0
HFD2_k127_3318762_1 protein kinase activity - - - 0.00000000000000000000000000002747 123.0
HFD2_k127_3318762_2 TIGRFAM repeat-companion domain TIGR02996 - - - 0.0000000000000000000000001201 120.0
HFD2_k127_3318762_3 WGR domain protein - - - 0.00000000003265 66.0
HFD2_k127_332603_0 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004282 290.0
HFD2_k127_332603_1 N-terminal domain of (some) glycogen debranching enzymes - - - 0.00000000000000000000000000000000881 139.0
HFD2_k127_332603_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000145 94.0
HFD2_k127_33347_0 Transglycosylase SLT domain K08306,K08309 - - 0.00000000000000000000000001884 124.0
HFD2_k127_3334795_0 AMP-binding enzyme K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 369.0
HFD2_k127_3334795_1 RNA cap guanine-N2 methyltransferase K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000007281 244.0
HFD2_k127_3334795_2 Phosphopantetheine attachment site - - - 0.00000000000000000001176 94.0
HFD2_k127_3342342_0 Phosphoesterase family K01114 - 3.1.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 369.0
HFD2_k127_3342668_1 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000000001695 87.0
HFD2_k127_3344943_0 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000005289 242.0
HFD2_k127_3344943_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000009125 145.0
HFD2_k127_3344943_2 helix_turn_helix, Lux Regulon - - - 0.0000156 51.0
HFD2_k127_3344943_3 OmpA family - - - 0.0002231 53.0
HFD2_k127_3345085_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 423.0
HFD2_k127_3345085_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 362.0
HFD2_k127_3345085_2 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 359.0
HFD2_k127_3345085_3 23S rRNA-intervening sequence protein - - - 0.0000000000003462 72.0
HFD2_k127_3347452_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 572.0
HFD2_k127_3347452_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 471.0
HFD2_k127_3347452_2 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000007088 194.0
HFD2_k127_3347452_3 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000001198 160.0
HFD2_k127_3347452_4 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.000000000000000000000000000000005086 131.0
HFD2_k127_3355808_0 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 334.0
HFD2_k127_3355808_1 PFAM Peptidase M19, renal dipeptidase K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000004946 254.0
HFD2_k127_3358167_0 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.0 1239.0
HFD2_k127_3358167_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004124 377.0
HFD2_k127_3358167_2 UbiA prenyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000002212 203.0
HFD2_k127_337015_0 NMT1-like family K15598 - - 0.000004704 52.0
HFD2_k127_3372421_0 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K02548 - 2.5.1.74 0.000000000000000000000000000000004367 139.0
HFD2_k127_3372421_1 OmpA family - - - 0.000000000004482 77.0
HFD2_k127_3374693_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009717 375.0
HFD2_k127_3376721_0 Surface antigen - - - 0.000000000000000000000000000000000000000000000000000000000000001219 233.0
HFD2_k127_3376721_1 Biopolymer transport protein ExbD/TolR - - - 0.0000000000000000000000000000000000000000004066 169.0
HFD2_k127_3377156_0 oligopeptide transporter, OPT family - - - 2.081e-298 926.0
HFD2_k127_3377156_1 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 355.0
HFD2_k127_3377156_2 Polysaccharide deacetylase K22278 - 3.5.1.104 0.0000000000000001533 86.0
HFD2_k127_3381946_0 alginic acid biosynthetic process K20276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001443 270.0
HFD2_k127_3381946_1 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000008597 234.0
HFD2_k127_3382873_0 COG0657 Esterase lipase - - - 0.00000000000000000000000000000002976 139.0
HFD2_k127_3382873_1 - - - - 0.00001214 56.0
HFD2_k127_3385496_0 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000025 119.0
HFD2_k127_3385496_1 von Willebrand factor type A domain - - - 0.000000000003701 69.0
HFD2_k127_3385496_2 Protein of unknown function (DUF4011) - - - 0.000003302 59.0
HFD2_k127_3385496_3 Protein phosphatase 2C - - - 0.000006514 53.0
HFD2_k127_3385518_0 Pyridoxal-phosphate dependent enzyme K01697,K01738 - 2.5.1.47,4.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 407.0
HFD2_k127_3385518_1 ubiE/COQ5 methyltransferase family K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 346.0
HFD2_k127_3385518_2 Major facilitator Superfamily K08223 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 296.0
HFD2_k127_3385518_3 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000003416 227.0
HFD2_k127_3385518_4 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000000000000006239 201.0
HFD2_k127_3385518_5 Belongs to the MIP aquaporin (TC 1.A.8) family - - - 0.0000000000000000000000000000000000000000000001992 168.0
HFD2_k127_3385518_6 Probably functions as a manganese efflux pump - - - 0.00000000000000000000000000000000000006721 151.0
HFD2_k127_3388636_0 TonB dependent receptor K16089 - - 0.0000000000000000000000000000008642 138.0
HFD2_k127_3388636_1 S1 and S6, chymotrypsin Hap - - - 0.0000001573 61.0
HFD2_k127_3389367_0 TonB-dependent Receptor Plug Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006568 534.0
HFD2_k127_3389367_1 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000007926 205.0
HFD2_k127_3389367_2 ribonuclease BN K07058 - - 0.00000000000000000000004386 111.0
HFD2_k127_3394217_0 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003244 271.0
HFD2_k127_3394217_1 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.000000000000000000000000000000000000000000000000000000000000005738 230.0
HFD2_k127_3394217_2 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 - - 0.000000000000000000000000000000004889 144.0
HFD2_k127_3394217_3 PFAM flagellar protein FliS K02422 - - 0.00000000000000003794 87.0
HFD2_k127_3396511_0 UMP kinase activity K00947,K09903 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0030151,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004154 304.0
HFD2_k127_3396511_1 PFAM aspartate glutamate uridylate kinase K00931,K03430,K06981 - 2.6.1.37,2.7.2.11,2.7.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004181 282.0
HFD2_k127_3396511_2 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.00000000000000000000000000000000000000000000000000000000000000000007466 244.0
HFD2_k127_3396511_3 transmembrane transporter activity K02008,K16783,K16785 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 - 0.000000000000000000000000000000000000000000003268 181.0
HFD2_k127_3396511_4 phosphate ion binding - - - 0.000000000005022 76.0
HFD2_k127_3396558_0 Tetratricopeptide repeat - - - 3.158e-202 651.0
HFD2_k127_3396558_1 Belongs to the GST superfamily K00799 - 2.5.1.18 0.0000000000000002364 86.0
HFD2_k127_3398501_0 aconitate hydratase K01681 - 4.2.1.3 7.518e-228 721.0
HFD2_k127_3398501_1 Biotin carboxylase K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 4.586e-221 694.0
HFD2_k127_3398501_3 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000103 156.0
HFD2_k127_3398501_4 Roadblock/LC7 domain - - - 0.000000000000000000000000000000001814 134.0
HFD2_k127_3398501_5 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000002206 97.0
HFD2_k127_3398501_6 - - - - 0.0000000000000000006028 96.0
HFD2_k127_3398501_7 Transcriptional regulator - - - 0.000000000000134 72.0
HFD2_k127_3398501_8 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00005647 50.0
HFD2_k127_3399298_0 Family membership K08884 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001174 295.0
HFD2_k127_3399298_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000001322 194.0
HFD2_k127_3399298_2 - - - - 0.00001041 57.0
HFD2_k127_3401006_0 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 496.0
HFD2_k127_3401006_1 pilus assembly protein PilW K02672 - - 0.00000000000000000000000001251 124.0
HFD2_k127_3402729_0 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 482.0
HFD2_k127_3412207_0 FHA domain - - - 0.0000000000000000000000000000000000000000000000000000000000001157 236.0
HFD2_k127_3412207_3 Tetratricopeptide repeats - - - 0.0000000000000000002972 89.0
HFD2_k127_3418653_0 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000007591 163.0
HFD2_k127_3418653_1 von Willebrand factor (vWF) type A domain - - - 0.000006514 53.0
HFD2_k127_3419773_0 - K07071 - - 0.00000000000000000000000000000000000000000000000004974 182.0
HFD2_k127_3419773_1 cellulose binding - - - 0.000000000000000003391 99.0
HFD2_k127_3419773_2 homoserine dehydrogenase K00003 - 1.1.1.3 0.000000002533 60.0
HFD2_k127_3426867_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 444.0
HFD2_k127_3426867_1 PEGA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 389.0
HFD2_k127_3426867_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009963 363.0
HFD2_k127_3429996_0 Highly conserved protein containing a thioredoxin domain - - - 0.000000000000000000000000000000000000004607 164.0
HFD2_k127_3432057_0 Belongs to the aldehyde dehydrogenase family K00128,K00130,K00146,K10217 - 1.2.1.3,1.2.1.32,1.2.1.39,1.2.1.8,1.2.1.85 1.044e-218 690.0
HFD2_k127_3432057_1 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 337.0
HFD2_k127_3432057_2 - - - - 0.0000000000000401 83.0
HFD2_k127_3434078_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 1.615e-204 651.0
HFD2_k127_3434078_1 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000000000000000003686 213.0
HFD2_k127_3434078_2 nucleotide catabolic process K10117 - - 0.0000000007864 70.0
HFD2_k127_3441343_0 - - - - 0.0000000000000000000000000000608 130.0
HFD2_k127_3442071_0 Cellulase (glycosyl hydrolase family 5) K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005916 556.0
HFD2_k127_3442071_1 peptidyl-tyrosine sulfation - - - 0.00000000005717 73.0
HFD2_k127_3443913_0 PEGA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007209 382.0
HFD2_k127_3443913_1 SMART alpha amylase catalytic sub domain K05343 - 3.2.1.1,5.4.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000668 335.0
HFD2_k127_3443913_2 Catalase - - - 0.0000000000000000000000000000000000000000643 169.0
HFD2_k127_3443913_3 Protein conserved in bacteria - - - 0.00000000000000000000000000000001593 136.0
HFD2_k127_3444045_0 - - - - 0.0000000000000000000000000000000000000000000000000323 184.0
HFD2_k127_3444045_1 Protein of unknown function (DUF2809) - - - 0.0000000000007321 74.0
HFD2_k127_3444045_2 Domain of unknown function (DUF5122) beta-propeller - - - 0.00007561 54.0
HFD2_k127_3447261_0 PFAM regulator of chromosome condensation, RCC1 - - - 0.000000000000000000000000000000000000000000000001625 192.0
HFD2_k127_3447261_1 Predicted methyltransferase regulatory domain - - - 0.00000000000000000000000000000000003667 152.0
HFD2_k127_3447261_2 Biopolymer transport protein ExbD/TolR K03559 - - 0.000000000000000000000000001917 119.0
HFD2_k127_3447261_3 Receptor K02014 - - 0.000008723 58.0
HFD2_k127_3447820_0 thiol oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 285.0
HFD2_k127_3447820_1 iron ion transport K07224 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006266 259.0
HFD2_k127_3447820_2 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000000000000000001931 169.0
HFD2_k127_3447820_3 Sodium:sulfate symporter transmembrane region - - - 0.0000000000000000000000000000000000000004317 158.0
HFD2_k127_3447820_4 Cupredoxin-like domain - - - 0.0000000000000000000001867 100.0
HFD2_k127_3447820_5 acetyltransferases and hydrolases with the alpha beta hydrolase fold K01046 - 3.1.1.3 0.00000000000000000003411 105.0
HFD2_k127_3447820_6 Iron permease FTR1 family K07243 - - 0.000000000001861 72.0
HFD2_k127_3449637_0 thiol oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006533 427.0
HFD2_k127_3449637_1 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000001106 162.0
HFD2_k127_3455650_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009895 603.0
HFD2_k127_3455650_1 TIGRFAM carbamoyl-phosphate synthase, small subunit K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008672 443.0
HFD2_k127_3455650_2 carbamoyl-phosphate synthetase ammonia chain K01955 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000003879 263.0
HFD2_k127_3455650_3 PFAM Radical SAM domain protein - - - 0.00000000000008317 76.0
HFD2_k127_3455855_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006559 332.0
HFD2_k127_3455855_1 Family membership K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000004834 285.0
HFD2_k127_3455855_3 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides - - - 0.0000000000000003219 81.0
HFD2_k127_3455855_4 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.000000000000001678 89.0
HFD2_k127_3455855_5 triphosphatase activity - - - 0.0000000000001491 81.0
HFD2_k127_3458049_0 TonB dependent receptor K16091 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003175 547.0
HFD2_k127_3458049_1 Horizontally Transferred TransMembrane Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 529.0
HFD2_k127_3458049_2 Imelysin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 308.0
HFD2_k127_3458049_3 - - - - 0.000000000000000000000000001176 125.0
HFD2_k127_3458277_0 DNA polymerase K02337,K14162 - 2.7.7.7 0.0 1466.0
HFD2_k127_3458277_1 WGR domain protein - - - 0.000000000000000000000000003089 128.0
HFD2_k127_3458277_2 domain protein - - - 0.000002557 59.0
HFD2_k127_3458277_3 WGR domain protein - - - 0.0003691 51.0
HFD2_k127_345870_0 ATP:ADP antiporter activity K01932,K03301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 472.0
HFD2_k127_345870_1 ATP ADP translocase K03301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 359.0
HFD2_k127_3462171_0 Cation transporter/ATPase, N-terminus K01531,K12955 - 3.6.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005055 538.0
HFD2_k127_3462171_1 AMP binding - - - 0.00000000000000000000000008728 117.0
HFD2_k127_3462171_2 hydrolase, family 65, central catalytic K10231 - 2.4.1.230 0.00000000000000009813 85.0
HFD2_k127_3463260_0 Nitrous oxide reductase K00376 - 1.7.2.4 1.208e-245 779.0
HFD2_k127_3463260_1 Domain present in carbohydrate binding proteins and sugar hydrolses K07218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005706 257.0
HFD2_k127_3463260_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000032 188.0
HFD2_k127_3463260_3 lipoprotein involved in nitrous oxide reduction - - - 0.000000000000000000000000000000000000000000003434 181.0
HFD2_k127_3463260_4 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.0000000000000000000000000000000000000000004452 165.0
HFD2_k127_3463260_5 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992,K19341 - - 0.0000000000000000000000000000000003742 145.0
HFD2_k127_3463260_6 thiolester hydrolase activity - - - 0.0000000000000000000006219 98.0
HFD2_k127_3463260_7 NosL - - - 0.0000000000000000005197 94.0
HFD2_k127_3464268_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006498 370.0
HFD2_k127_3464268_1 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000287 236.0
HFD2_k127_3465932_0 PFAM MotA TolQ ExbB proton channel K02556 - - 0.00000000000000000000000000000000000000000000000000000000000001793 224.0
HFD2_k127_3465932_1 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.00000000000000000000000000000000000000000001375 171.0
HFD2_k127_3465932_2 PFAM flagellar FlbD family protein K02385 - - 0.0000001827 59.0
HFD2_k127_3465932_3 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.00000133 59.0
HFD2_k127_3468561_0 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003666 568.0
HFD2_k127_3468561_1 - - - - 0.0000000000000000000000000000000000000000000004939 179.0
HFD2_k127_3468561_2 FHA domain - - - 0.0000000000000000000000000483 121.0
HFD2_k127_3468561_3 metallopeptidase activity K01637 - 4.1.3.1 0.0000001062 60.0
HFD2_k127_3471046_0 NUBPL iron-transfer P-loop NTPase K04562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007839 471.0
HFD2_k127_3471046_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009631 394.0
HFD2_k127_3471046_2 cheY-homologous receiver domain K07657 - - 0.0000000000000002588 81.0
HFD2_k127_3472856_0 response to abiotic stimulus K06867 - - 2.847e-305 940.0
HFD2_k127_3472856_2 Ndr family K01055 - 3.1.1.24 0.0000000000000000000000000000000000000002853 160.0
HFD2_k127_3472856_3 PFAM Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000001418 136.0
HFD2_k127_3472856_4 translation initiation factor activity K01972,K02342,K03646 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 2.7.7.7,6.5.1.2 0.000000000000000000000000000008576 131.0
HFD2_k127_3472856_5 FR47-like protein - - - 0.000000000000001229 84.0
HFD2_k127_3472856_6 carboxylic ester hydrolase activity K12132 - 2.7.11.1 0.000000005262 59.0
HFD2_k127_3479212_0 DNA mismatch repair protein K07456 - - 2.212e-200 642.0
HFD2_k127_3479558_0 Prephenate dehydratase K04518,K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001193 273.0
HFD2_k127_3479558_1 Involved in the degradation of specific anti-sigma factors - - - 0.0000000000000000001312 104.0
HFD2_k127_3500833_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007345 614.0
HFD2_k127_3500833_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 398.0
HFD2_k127_3500833_2 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001025 269.0
HFD2_k127_3500833_3 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.3.2.6 0.00000000000000000000000000000000000000000000000000001132 198.0
HFD2_k127_3500833_5 Belongs to the BolA IbaG family K05527 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.0001147 45.0
HFD2_k127_3501470_1 isomerase activity - - - 0.00000000000000000000001338 117.0
HFD2_k127_3503153_0 The M ring may be actively involved in energy transduction K02409 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007065 289.0
HFD2_k127_3503153_1 Flagellar basal body rod FlgEFG protein C-terminal K02388 - - 0.0000000000000000000000000000000000001492 145.0
HFD2_k127_3503153_2 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02410 - - 0.000001142 56.0
HFD2_k127_3503153_3 Flagellar hook-basal body complex protein FliE K02408 - - 0.00003266 55.0
HFD2_k127_3525053_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007994 526.0
HFD2_k127_3525053_1 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000005351 108.0
HFD2_k127_3525053_2 COG1063 Threonine dehydrogenase and related Zn-dependent - - - 0.0005067 45.0
HFD2_k127_3525942_0 Protein of unknown function (DUF3570) - - - 0.0000000000000000000000000000000006468 145.0
HFD2_k127_3525942_2 Domain of unknown function (DUF4266) - - - 0.0000001373 56.0
HFD2_k127_3525981_0 Pyridoxal-phosphate dependent enzyme K01697 - 4.2.1.22 4.535e-212 671.0
HFD2_k127_3525981_1 Putative RNA methylase family UPF0020 - - - 0.00000000000000000000000000000000000000000000000000000766 198.0
HFD2_k127_3525981_2 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000006557 181.0
HFD2_k127_3529696_0 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000007383 245.0
HFD2_k127_3529696_1 PFAM Hemolysin-type calcium-binding repeat (2 copies) - - - 0.00000000000000000000000000000000000000000000001487 183.0
HFD2_k127_3529696_2 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000004683 166.0
HFD2_k127_3532918_0 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000003759 213.0
HFD2_k127_3532918_1 - - - - 0.00000000000000000000000000006553 123.0
HFD2_k127_3533906_0 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 316.0
HFD2_k127_3533906_1 Family membership K08884,K12132 - 2.7.11.1 0.0000005043 60.0
HFD2_k127_3536619_0 ABC-type multidrug transport system, ATPase and permease K06147 - - 5.937e-258 811.0
HFD2_k127_3536619_1 D-alanyl-D-alanine carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000003476 197.0
HFD2_k127_3537393_0 PFAM ADP-ribosylglycohydrolase K05521 - 3.2.2.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004954 290.0
HFD2_k127_3537393_1 Bacterial regulatory proteins, tetR family - - - 0.000000000000004976 85.0
HFD2_k127_3540314_0 non-ribosomal peptide synthetase - - - 3.964e-231 750.0
HFD2_k127_3543891_0 UDP-glucoronosyl and UDP-glucosyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000002461 234.0
HFD2_k127_3546188_0 containing an amidase domain and an AraC-type DNA-binding HTH domain - - - 0.00000000000000000000000000000000000000000000000000000000000000003342 229.0
HFD2_k127_3546188_1 TIGRFAM repeat-companion domain TIGR02996 - - - 0.0000000873 65.0
HFD2_k127_3546188_2 Phosphoglycerol transferase and related proteins alkaline phosphatase superfamily - - - 0.00004759 57.0
HFD2_k127_3546188_3 regulation of response to stimulus - - - 0.00005239 56.0
HFD2_k127_3547719_0 Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000008423 226.0
HFD2_k127_3547719_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00003002 48.0
HFD2_k127_3548633_0 PFAM Formylglycine-generating sulfatase enzyme K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000406 201.0
HFD2_k127_3548633_1 DNA-templated transcription, initiation - - - 0.000000000000000000000000000599 123.0
HFD2_k127_3548633_2 Serine threonine protein kinase - - - 0.000000000000009719 87.0
HFD2_k127_3553704_0 Belongs to the UPF0145 family - - - 0.000000000000000000000000000000000000000001202 169.0
HFD2_k127_3553704_1 Belongs to the UPF0145 family - - - 0.00000000000000000000000001709 113.0
HFD2_k127_3553704_2 Protein conserved in bacteria K09986 - - 0.0000000000000004877 81.0
HFD2_k127_3553704_3 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000548 59.0
HFD2_k127_3555539_0 Dynamin family - - - 1.721e-215 685.0
HFD2_k127_3555539_1 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000332 202.0
HFD2_k127_3569209_0 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 7.056e-242 783.0
HFD2_k127_3569209_1 AAA domain - - - 0.00000000000000001284 86.0
HFD2_k127_3569608_1 Belongs to the ompA family K03640 - - 0.00000000000000000000000006415 123.0
HFD2_k127_3569608_2 TIGRFAM repeat-companion domain TIGR02996 - - - 0.0009174 51.0
HFD2_k127_357353_0 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000000003022 151.0
HFD2_k127_357353_1 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.0000000000000000000000000000000003556 144.0
HFD2_k127_357353_2 serine threonine protein kinase - - - 0.0000000000000000001688 100.0
HFD2_k127_357353_3 SPFH domain-Band 7 family - - - 0.00002855 51.0
HFD2_k127_3576584_0 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain K02488 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 2.7.7.65 0.00000000000000000000000000000000000000000000002692 190.0
HFD2_k127_3576584_1 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.0000000000000000000000000000000000000000000198 173.0
HFD2_k127_3576584_2 cheY-homologous receiver domain K03413 - - 0.0000000000000000000000000002593 124.0
HFD2_k127_3576584_3 Dodecin K09165 - - 0.0000000000000000005795 92.0
HFD2_k127_3577074_0 Alpha-2-Macroglobulin K06894 - - 7.999e-236 751.0
HFD2_k127_3577074_1 Transglycosylase K05367 - 2.4.1.129 0.0000000000000000000003834 103.0
HFD2_k127_3590557_0 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000009438 162.0
HFD2_k127_3590557_1 WGR domain protein - - - 0.000000000000000000000000000001283 134.0
HFD2_k127_35915_0 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.000000000000000000000000000000000000000000006457 166.0
HFD2_k127_35915_1 - - - - 0.000000000000000000000000000000000000000005907 164.0
HFD2_k127_35915_2 - - - - 0.0000000000000000000000000000000000000006833 158.0
HFD2_k127_3596982_0 - - - - 0.0000000000000000000000000000000000009591 144.0
HFD2_k127_3600120_0 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000001063 208.0
HFD2_k127_3600120_1 AAA ATPase domain - - - 0.0000000000000000000000000000000000000007039 165.0
HFD2_k127_3600120_2 Bacterial transcriptional activator domain - - - 0.000000000003607 79.0
HFD2_k127_3602395_0 cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000007511 231.0
HFD2_k127_3602395_1 protein related to plant photosystem II stability assembly factor - - - 0.00000000002236 75.0
HFD2_k127_3602395_2 - - - - 0.0000000003053 61.0
HFD2_k127_3604459_0 protein kinase activity - - - 7.533e-217 690.0
HFD2_k127_3622134_0 Transglycosylase SLT domain K08309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002214 299.0
HFD2_k127_3622134_1 CBS domain - - - 0.00000000000000000000000000000000000000000000009093 180.0
HFD2_k127_3623799_0 TIGRFAM methylmalonate-semialdehyde dehydrogenase K00140 - 1.2.1.18,1.2.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 285.0
HFD2_k127_3623799_1 DNA-binding transcription factor activity K03828 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008409 254.0
HFD2_k127_3623799_2 COG0433 Predicted ATPase - - - 0.0001663 49.0
HFD2_k127_3629413_0 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009149 361.0
HFD2_k127_3629413_1 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000002432 131.0
HFD2_k127_3633406_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007968 392.0
HFD2_k127_3633406_1 Chymotrypsin-like elastase family, member K01345,K01346,K09632,K20751 - 3.4.21.70,3.4.21.71,3.4.21.99 0.0006451 50.0
HFD2_k127_3637449_0 Protein-arginine deiminase (PAD) middle domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004216 415.0
HFD2_k127_3637449_1 deoxyhypusine monooxygenase activity - - - 0.000000000000000000000000002747 123.0
HFD2_k127_3646829_0 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001293 263.0
HFD2_k127_3649509_0 Putative glutamine amidotransferase - - - 4.912e-214 688.0
HFD2_k127_3649509_1 TonB-dependent Receptor Plug Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006294 449.0
HFD2_k127_3649509_2 Protein kinase domain K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 357.0
HFD2_k127_3649509_3 N-terminal double-transmembrane domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001258 283.0
HFD2_k127_3649509_4 phosphate ion binding - - - 0.000000000000000000000000000000000000000000000000000000001788 220.0
HFD2_k127_3649509_5 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000008879 200.0
HFD2_k127_3649509_6 glutamate-cysteine ligase activity - - - 0.000000000000000000000000000000000000000000002039 169.0
HFD2_k127_3651689_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000053 278.0
HFD2_k127_3651689_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007552 282.0
HFD2_k127_3651689_3 Tetratricopeptide repeat - - - 0.0000000000000001073 85.0
HFD2_k127_3652159_0 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003491 366.0
HFD2_k127_3652159_1 AMP-binding enzyme C-terminal domain K02182 - 6.2.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 359.0
HFD2_k127_3652159_2 Permease MlaE K02066 - - 0.0000000000000000000000000000000000007646 142.0
HFD2_k127_3652159_3 Secretory protein of YscJ/FliF family K03222 - - 0.00000000000000000000000119 114.0
HFD2_k127_3656301_0 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000009158 276.0
HFD2_k127_3656301_1 extracellular polysaccharide biosynthetic process - - - 0.00000000000000000000000000007237 133.0
HFD2_k127_3656301_2 -O-antigen K02847 - - 0.00000000000000001435 89.0
HFD2_k127_3656301_3 Polysaccharide biosynthesis protein - - - 0.000002238 51.0
HFD2_k127_366487_0 amine dehydrogenase activity - - - 0.000000000000000000002739 107.0
HFD2_k127_366487_2 O-methyltransferase activity - - - 0.000000004011 59.0
HFD2_k127_3680036_0 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000007004 177.0
HFD2_k127_3680036_1 Peptidyl-prolyl cis-trans isomerase - GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005794,GO:0005802,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0012505,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0031410,GO:0031982,GO:0031984,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044431,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0097708,GO:0098791,GO:0140096,GO:1901564 - 0.00000000000000000000000000000001996 140.0
HFD2_k127_3681891_0 ERAP1-like C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 421.0
HFD2_k127_3690119_0 Sulfatase-modifying factor enzyme 1 K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 505.0
HFD2_k127_3690119_1 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000002963 253.0
HFD2_k127_3693830_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000007251 155.0
HFD2_k127_3693830_1 Universal stress protein - - - 0.000000000000000000000000009668 116.0
HFD2_k127_3702247_0 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 325.0
HFD2_k127_3702247_1 Transporter associated domain K06189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006293 339.0
HFD2_k127_3702247_2 Domain of unknown function (DUF4178) - - - 0.00000000000000000000000175 118.0
HFD2_k127_3703637_0 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000000000000001887 217.0
HFD2_k127_3703637_1 deacetylase K22278 - 3.5.1.104 0.0000000000000000000000000000000000005213 154.0
HFD2_k127_3704775_0 Domain of unknown function (DUF2088) - - - 2.923e-275 854.0
HFD2_k127_3704775_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000907 112.0
HFD2_k127_3704787_0 Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor) K17763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007604 313.0
HFD2_k127_3704787_1 AMP binding - GO:0008150,GO:0040007 - 0.00000000000000000000000000000000002817 140.0
HFD2_k127_3704787_2 Anti-sigma regulatory factor (Ser Thr protein kinase) K17752 - 2.7.11.1 0.0000000000000000000000000000000003091 137.0
HFD2_k127_3704787_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000005068 126.0
HFD2_k127_3704787_4 Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor) K17762 - - 0.00000000000000000000000000001947 121.0
HFD2_k127_3704787_5 Anti-sigma regulatory factor Ser Thr protein kinase - - - 0.0000000000000000000000000001952 130.0
HFD2_k127_3709568_0 - Catabolite gene activator and regulatory subunit of cAMP-dependent protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 516.0
HFD2_k127_3709568_2 - - - - 0.000000000000000001174 93.0
HFD2_k127_3711681_0 ATPase activity K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004195 341.0
HFD2_k127_3712108_0 RmlD substrate binding domain K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003672 457.0
HFD2_k127_3712108_1 Phosphate acyltransferases - - - 0.0000102 49.0
HFD2_k127_3714165_0 Two component, sigma54 specific, transcriptional regulator, Fis family K07712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006515 544.0
HFD2_k127_3714165_1 FHA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003466 306.0
HFD2_k127_3714165_2 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006376 284.0
HFD2_k127_3714165_3 - - - - 0.000000000000000000000549 110.0
HFD2_k127_3714165_4 heat shock protein binding - - - 0.0000001204 63.0
HFD2_k127_3714165_5 Protein tyrosine kinase K08884,K12132 - 2.7.11.1 0.0003849 51.0
HFD2_k127_3714283_0 Lysine-2,3-aminomutase K01843 - 5.4.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002308 348.0
HFD2_k127_3714283_1 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.0000000000000000000000000007939 117.0
HFD2_k127_3714283_2 protein trimerization K07114 - - 0.000000000000000000000000000852 130.0
HFD2_k127_37201_0 - - - - 0.000000000000000000000000000005928 137.0
HFD2_k127_3722398_0 adventurous gliding protein T - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 347.0
HFD2_k127_3724526_0 amine dehydrogenase activity - - - 0.00000000000000000000000000002451 123.0
HFD2_k127_3727418_0 Carboxyl transferase domain K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007659 294.0
HFD2_k127_3727418_1 Fungal chitosanase of glycosyl hydrolase group 75 - - - 0.0000000000000000000000000000000000000000000000000000000001138 216.0
HFD2_k127_3729992_0 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 587.0
HFD2_k127_3729992_1 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.00000000000000001638 84.0
HFD2_k127_3729992_2 Histidine phosphatase superfamily (branch 1) K08296 - - 0.0004252 49.0
HFD2_k127_375539_0 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 3.809e-251 782.0
HFD2_k127_375539_1 Aldehyde dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006756 277.0
HFD2_k127_3761471_1 NapC/NirT cytochrome c family, N-terminal region K02569 - - 0.0000000000000000000000000000000000000000000000000000000002183 211.0
HFD2_k127_3761471_2 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000001004 157.0
HFD2_k127_3761471_3 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000003014 134.0
HFD2_k127_3766539_0 Family membership K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 308.0
HFD2_k127_3766539_1 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000001993 195.0
HFD2_k127_3766539_2 DoxX K15977 - - 0.000000000000000000000000000000000000002059 154.0
HFD2_k127_3766539_3 Isochorismatase family K08281 - 3.5.1.19 0.00000000000000000000000000000000004457 146.0
HFD2_k127_3770210_0 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 450.0
HFD2_k127_3770718_0 Uncharacterized protein conserved in bacteria (DUF2330) - - - 0.00000000000000000000000000000000000000000000000000000000000000000003806 250.0
HFD2_k127_3770718_1 Rhodanese Homology Domain - - - 0.0000000000000000000000001447 112.0
HFD2_k127_3770718_2 Metallo-beta-lactamase superfamily protein - - - 0.00000000000000000002278 92.0
HFD2_k127_3775453_0 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 6.269e-219 701.0
HFD2_k127_3775453_1 Belongs to the SEDS family K05837 - - 0.000000000000000000000000000000000000000000000000000000000002212 212.0
HFD2_k127_3777097_0 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 337.0
HFD2_k127_3777097_1 heat shock protein 70 K04043 - - 0.000000000000000000000000000000000000000000000004314 175.0
HFD2_k127_3777097_3 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000584 160.0
HFD2_k127_3777097_4 - - - - 0.00000000000000000000000004755 122.0
HFD2_k127_3777097_5 Outer membrane efflux protein - - - 0.000003396 49.0
HFD2_k127_3784476_0 Pfam:Pyridox_oxidase K01768 - 4.6.1.1 0.0000000000000000000000000000000009421 146.0
HFD2_k127_3784476_1 GAF domain - - - 0.00000000000000000000000000000001371 142.0
HFD2_k127_3784476_2 pyridoxamine 5-phosphate - - - 0.00000007449 60.0
HFD2_k127_3788221_0 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002464 293.0
HFD2_k127_3788221_1 - - - - 0.000000000000000000000000000000003224 138.0
HFD2_k127_3788221_2 Oxidoreductase molybdopterin binding domain K07147 - - 0.0000000007258 65.0
HFD2_k127_3790820_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 362.0
HFD2_k127_3790820_2 ABC transporter K02003 - - 0.0000000000000000000000000008939 122.0
HFD2_k127_3790820_3 Psort location Cytoplasmic, score 8.96 - - - 0.000000001336 68.0
HFD2_k127_3794786_0 acyl transferase domain K16128 - - 5.187e-212 706.0
HFD2_k127_3794786_1 synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001394 241.0
HFD2_k127_3795_0 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000007588 158.0
HFD2_k127_3797386_0 - - - - 0.00000000000000000000000000003327 127.0
HFD2_k127_3797386_1 N-succinyltransferase beta subunit K00673 - 2.3.1.109 0.00000000000000000002015 94.0
HFD2_k127_3800786_0 TIGRFAM decaheme c-type cytochrome, OmcA MtrC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003029 271.0
HFD2_k127_3800786_1 PFAM SMP-30 Gluconolaconase - - - 0.000000000000007109 82.0
HFD2_k127_3800786_2 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.00005074 55.0
HFD2_k127_3801379_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 419.0
HFD2_k127_3801379_1 vancomycin resistance protein K18346 - - 0.00000000008764 71.0
HFD2_k127_380351_0 Peptidase dimerisation domain K01295 - 3.4.17.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003181 467.0
HFD2_k127_380351_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 431.0
HFD2_k127_380351_2 fatty acid hydroxylase - - - 0.00000000000000000000000000000000000000000001259 177.0
HFD2_k127_380351_3 Transcription factor zinc-finger K09981 - - 0.0000000006407 67.0
HFD2_k127_3804184_0 Family membership K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000004547 228.0
HFD2_k127_3804184_1 amine dehydrogenase activity - - - 0.00000000000000000004354 104.0
HFD2_k127_3804184_2 bacterial-type flagellum organization - - - 0.0000000000001194 75.0
HFD2_k127_3817418_0 Cytochrome c K08685 - 1.4.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008975 320.0
HFD2_k127_3817418_1 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.00000598 52.0
HFD2_k127_3820469_0 DEAD DEAH box K03724 - - 0.0 1229.0
HFD2_k127_3823351_0 Domain of unknown function (DUF4419) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001515 298.0
HFD2_k127_3823351_1 DNA polymerase LigD polymerase domain K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000597 260.0
HFD2_k127_3824346_0 Tfp pilus assembly protein FimV - - - 0.000000000000000000000421 110.0
HFD2_k127_3824346_1 Protein of unknown function (DUF790) K09744 - - 0.00001763 53.0
HFD2_k127_3825147_0 Cytochrome c K08685 - 1.4.9.1 0.00000000000000000000000000000000000000000000000000000000000002759 226.0
HFD2_k127_3825147_1 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000002908 197.0
HFD2_k127_3825147_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000009582 157.0
HFD2_k127_3825972_0 Acyl-CoA oxidase K00232 - 1.3.3.6 1.638e-198 646.0
HFD2_k127_3825972_1 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001335 269.0
HFD2_k127_3825972_2 - - - - 0.00000002491 64.0
HFD2_k127_3829077_0 Beta propeller domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 450.0
HFD2_k127_3829077_1 oxidoreductase activity K07114 - - 0.00000000001153 73.0
HFD2_k127_3830462_0 WGR domain protein - - - 0.0000000000000000002021 101.0
HFD2_k127_3830462_1 bacterial-type flagellum-dependent cell motility - - - 0.000000001462 64.0
HFD2_k127_3831935_0 - - - - 0.0000000000000000000000000000000000000000000000000000006441 213.0
HFD2_k127_3831935_1 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791,K13019 - 5.1.3.14,5.1.3.23 0.0000000000000000000004725 98.0
HFD2_k127_3831935_2 - - - - 0.00000000000000002551 87.0
HFD2_k127_383226_0 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01190,K05350,K12308 - 3.2.1.21,3.2.1.23 2.309e-202 652.0
HFD2_k127_3834773_0 Phosphoenolpyruvate phosphomutase K01637 - 4.1.3.1 1.998e-213 671.0
HFD2_k127_3834773_1 Malate synthase K01638 - 2.3.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004106 569.0
HFD2_k127_3834773_2 - - - - 0.00000000000000000000000000000000003348 141.0
HFD2_k127_3834773_3 - - - - 0.0000000000000000000000001985 110.0
HFD2_k127_3837095_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000001525 199.0
HFD2_k127_3837095_1 cell envelope organization K05807,K08309 - - 0.00000000000009899 80.0
HFD2_k127_3838260_0 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000000000000238 230.0
HFD2_k127_3838260_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000004698 214.0
HFD2_k127_3843356_0 long-chain fatty acid transporting porin activity K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001574 262.0
HFD2_k127_3843356_1 TLC ATP/ADP transporter K03301 - - 0.0000000000000000000000000000005779 141.0
HFD2_k127_3843356_2 Copper type II ascorbate-dependent monooxygenase, C-terminal domain - - - 0.00000000001876 72.0
HFD2_k127_3843356_3 regulator 1 - GO:0003008,GO:0007600,GO:0008150,GO:0019233,GO:0032501,GO:0050877 - 0.0000007916 61.0
HFD2_k127_3845813_0 HB1, ASXL, restriction endonuclease HTH domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000653 463.0
HFD2_k127_384994_0 Family membership - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 416.0
HFD2_k127_384994_1 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001712 275.0
HFD2_k127_384994_2 FR47-like protein - - - 0.00000000000000001789 93.0
HFD2_k127_3869820_0 Alpha-amylase domain K01176 - 3.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 375.0
HFD2_k127_3869820_1 amino acid activation for nonribosomal peptide biosynthetic process K20952 - - 0.000000000000000000000000000000000001033 156.0
HFD2_k127_3871118_0 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.00000000000000000000000000001617 121.0
HFD2_k127_3871118_2 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.0000001698 57.0
HFD2_k127_3871118_4 EF hand - - - 0.0001188 53.0
HFD2_k127_3875783_0 Peptidase dimerisation domain K12941 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008367 466.0
HFD2_k127_3875783_1 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 389.0
HFD2_k127_3875783_2 Belongs to the PEP-utilizing enzyme family K08484 - 2.7.3.9 0.000000000000000000000000000000000000000000000000000000000000000002332 233.0
HFD2_k127_3876022_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000005082 214.0
HFD2_k127_3876022_1 protein conserved in bacteria K09983 - - 0.0000000000000000000000000000000000000000000000005716 181.0
HFD2_k127_3876022_2 HD domain K07023 - - 0.000000000000000000000000000000001426 138.0
HFD2_k127_3876022_3 CDP-alcohol phosphatidyltransferase K00993 - 2.7.8.1 0.000000000007592 76.0
HFD2_k127_3876022_4 DNA polymerase X family K02347 - - 0.0000003943 54.0
HFD2_k127_3880724_0 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005765 467.0
HFD2_k127_3880724_1 Aldehyde dehydrogenase family K00128,K00135 - 1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 449.0
HFD2_k127_3880724_2 leucine binding - - - 0.000000000000000000000000000000000000000000000000000000003401 214.0
HFD2_k127_3881335_0 Belongs to the N(4) N(6)-methyltransferase family K00590 - 2.1.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000005904 261.0
HFD2_k127_3881335_1 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000000000000000000000000002075 219.0
HFD2_k127_3881335_2 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000000000000000000000000000000000000000002794 169.0
HFD2_k127_3881335_3 snoRNA binding - - - 0.000000000000008059 83.0
HFD2_k127_3885274_1 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000006593 204.0
HFD2_k127_3885274_2 Belongs to the HesB IscA family K13628 - - 0.000000000000000000000000000000000000000000000000002673 183.0
HFD2_k127_3891218_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 GO:0000166,GO:0003674,GO:0003824,GO:0004353,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006807,GO:0006950,GO:0006970,GO:0006995,GO:0007154,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009267,GO:0009314,GO:0009416,GO:0009605,GO:0009628,GO:0009642,GO:0009646,GO:0009651,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0016491,GO:0016638,GO:0016639,GO:0017076,GO:0019222,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0035639,GO:0036094,GO:0042221,GO:0042594,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043562,GO:0044424,GO:0044444,GO:0044464,GO:0046686,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0050897,GO:0051171,GO:0051716,GO:0055114,GO:0065007,GO:0071496,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901698 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 316.0
HFD2_k127_3891218_1 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001233 293.0
HFD2_k127_3892194_0 double-stranded DNA 3'-5' exodeoxyribonuclease activity K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001957 279.0
HFD2_k127_3892194_1 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.00000000002919 76.0
HFD2_k127_3893196_0 oxidoreductase activity K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 359.0
HFD2_k127_3893196_1 phosphorelay signal transduction system K10941 - - 0.00000000000000000000000011 113.0
HFD2_k127_3893196_2 Glycosyl Transferase - - - 0.000000152 61.0
HFD2_k127_389671_0 phosphorelay signal transduction system K01768,K10941,K11894 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005774 398.0
HFD2_k127_3907909_0 Aminotransferase class-III K03918,K07250,K20428 - 2.6.1.19,2.6.1.22,2.6.1.33,2.6.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000906 467.0
HFD2_k127_3907909_1 MMPL family K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 458.0
HFD2_k127_3907909_2 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000001257 192.0
HFD2_k127_3907909_3 phosphatidate phosphatase activity - - - 0.000000000000000000000000000000000004968 154.0
HFD2_k127_3907909_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000000001811 146.0
HFD2_k127_3907909_5 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008962,GO:0009058,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030258,GO:0031224,GO:0031226,GO:0032026,GO:0042221,GO:0042577,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0046839,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901576 3.1.3.27 0.00000000000000000001027 106.0
HFD2_k127_3907909_6 - - - - 0.000000000000000001038 97.0
HFD2_k127_3907909_7 PFAM RNA recognition motif - - - 0.00000000000000002618 89.0
HFD2_k127_3907909_8 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000043 71.0
HFD2_k127_3911767_0 PFAM Rhodanese domain protein K03892 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001563 256.0
HFD2_k127_3912182_0 PFAM Formylglycine-generating sulfatase enzyme K12132 - 2.7.11.1 0.0000000000000000000000000000000000004332 158.0
HFD2_k127_3913828_0 helicase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 505.0
HFD2_k127_3913828_1 Sulfatase K01133 - 3.1.6.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 333.0
HFD2_k127_3913828_2 fatty acid desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002031 263.0
HFD2_k127_3916491_0 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000716 183.0
HFD2_k127_3916491_1 - - - - 0.000000000000000000000000000000000000000001536 166.0
HFD2_k127_3916491_2 response regulator K02488 - 2.7.7.65 0.0000000001151 65.0
HFD2_k127_3919132_0 Protein kinase domain K08884 - 2.7.11.1 0.0000000000000000000000000000000000000002405 166.0
HFD2_k127_3919132_1 protein trimerization - - - 0.0000005189 62.0
HFD2_k127_3919132_2 Receptor family ligand binding region - - - 0.0005476 51.0
HFD2_k127_3919398_0 Belongs to the ABC transporter superfamily K02031,K12371,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000876 399.0
HFD2_k127_3919398_1 Belongs to the ABC transporter superfamily K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 391.0
HFD2_k127_3919398_2 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 300.0
HFD2_k127_3919398_3 PrkA serine protein kinase C-terminal domain - - - 0.00000000000000000000000000000000000000000002741 164.0
HFD2_k127_3919398_5 - - - - 0.000001297 52.0
HFD2_k127_3922041_0 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 391.0
HFD2_k127_3922041_1 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 321.0
HFD2_k127_3922041_2 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000001576 216.0
HFD2_k127_3922041_4 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.000005221 56.0
HFD2_k127_3922041_5 - - - - 0.000008095 54.0
HFD2_k127_3922041_6 - - - - 0.000009591 56.0
HFD2_k127_3922490_0 pyruvate phosphate dikinase K01006 - 2.7.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 564.0
HFD2_k127_3924827_0 Catalyzes the oxidation of dihydrolipoamide to lipoamide K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 414.0
HFD2_k127_3924827_1 Redoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 296.0
HFD2_k127_3925939_0 Flagellar basal body rod FlgEFG protein C-terminal K02396 - - 0.000000000000000000000000000000000000000007221 171.0
HFD2_k127_3925939_1 Bacterial flagellin N-terminal helical region K02397 - - 0.000000000000000000000002501 115.0
HFD2_k127_3925939_2 Rod binding protein K02395 - - 0.000007758 52.0
HFD2_k127_3925939_3 - - - - 0.0001978 49.0
HFD2_k127_3928663_0 Methyltransferase domain K00588 - 2.1.1.104 0.00000000000000000000000000000000000000000000001038 179.0
HFD2_k127_3928663_2 Bacterial-like globin K06886 - - 0.00000165 57.0
HFD2_k127_3933607_0 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009095 359.0
HFD2_k127_3933607_1 cytochrome oxidase assembly K02259 - - 0.00006513 47.0
HFD2_k127_3934856_0 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002836 458.0
HFD2_k127_3934856_1 Belongs to the heat shock protein 70 family - - - 0.0001228 47.0
HFD2_k127_3935544_1 Beta-L-arabinofuranosidase, GH127 - - - 0.0000006916 61.0
HFD2_k127_3935544_2 Mur ligase middle domain - - - 0.000001232 60.0
HFD2_k127_3946689_0 MazG nucleotide pyrophosphohydrolase domain K02499,K04765 - 3.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 362.0
HFD2_k127_3946689_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000003322 226.0
HFD2_k127_3946689_2 SAICAR synthetase K01923 - 6.3.2.6 0.000000000000004737 81.0
HFD2_k127_3946805_0 Family membership - - - 0.000000000000000000000000000000000000000000000000000000000001968 224.0
HFD2_k127_3946805_1 DNA-binding regulatory protein K03088 - - 0.0000000000000000000000000000001328 135.0
HFD2_k127_3946805_2 - - - - 0.0000000000000001156 85.0
HFD2_k127_3948966_0 PFAM AMP-dependent synthetase and ligase K02182 - 6.2.1.48 1.718e-211 693.0
HFD2_k127_3948966_1 PFAM Mo-dependent nitrogenase - - - 0.000000000000000000000000000000000000000003296 165.0
HFD2_k127_3948966_2 von Willebrand factor (vWF) type A domain - - - 0.0004482 48.0
HFD2_k127_3953717_0 AMP-binding enzyme C-terminal domain K08295 - 6.2.1.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 475.0
HFD2_k127_3953717_1 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 348.0
HFD2_k127_3953717_2 Capsule biosynthesis protein capA K07282 - - 0.00000000000000000000000000000000000000000000001565 177.0
HFD2_k127_3966332_0 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000002581 258.0
HFD2_k127_3966332_1 Lactonase, 7-bladed beta-propeller - - - 0.0000000000000000000000000000000000000000000000000000000000002245 231.0
HFD2_k127_3966332_2 Domain of unknown function (DUF4331) - - - 0.0000000000000000001443 93.0
HFD2_k127_3967149_0 Inward rectifier potassium channel K08715 - - 0.000000000000000000000000000000000000000000000000000000000000000000005408 244.0
HFD2_k127_3967149_1 cAMP phosphodiesterases class-II K01120 - 3.1.4.17 0.00000000000000000000000000000000000000000000000000000000000000000009222 235.0
HFD2_k127_3967149_2 Thioredoxin-like - - - 0.00000000000000000000000000005196 124.0
HFD2_k127_3967464_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003572 597.0
HFD2_k127_3967464_1 Acetyltransferase (GNAT) domain K03817 - - 0.00001934 48.0
HFD2_k127_3980549_0 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005269 438.0
HFD2_k127_3980549_1 acetylornithine aminotransferase K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000337 408.0
HFD2_k127_3980549_2 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 375.0
HFD2_k127_3980549_3 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001147 241.0
HFD2_k127_3980634_0 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 417.0
HFD2_k127_3987936_0 polysaccharide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002536 294.0
HFD2_k127_3993638_0 AcrB/AcrD/AcrF family K07787,K15726 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004413 495.0
HFD2_k127_3993638_1 Bacterial PH domain - - - 0.000000000000000000000002739 117.0
HFD2_k127_3993638_2 COG3000 Sterol desaturase - - - 0.00004764 52.0
HFD2_k127_3996900_0 Biotin carboxylase C-terminal domain K01941,K01961 - 6.3.4.14,6.3.4.6,6.4.1.2 5.888e-212 668.0
HFD2_k127_3996900_2 Periplasmic Protein - - - 0.000000000000000000000000000002773 129.0
HFD2_k127_3998043_0 Belongs to the RimK family K05844,K14940 - 6.3.2.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 438.0
HFD2_k127_3998043_1 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000002592 164.0
HFD2_k127_3998043_2 Aminotransferase class-V K01556 - 3.7.1.3 0.000005466 49.0
HFD2_k127_4000368_0 PFAM Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001458 276.0
HFD2_k127_4000368_1 iron ion binding - - - 0.00000000000000000000000000000000000000000000000000000002137 206.0
HFD2_k127_4007259_0 Alpha-2-Macroglobulin K06894 - - 0.000000000000000000000000000000000000000000000000000000000001882 238.0
HFD2_k127_4007259_1 serine-type endopeptidase activity K07261 - - 0.000000000000000000000000000000000000000000000000000000006029 214.0
HFD2_k127_4015376_0 Acyclic terpene utilisation family protein AtuA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 538.0
HFD2_k127_4015376_2 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00005331 55.0
HFD2_k127_4017027_0 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007047 351.0
HFD2_k127_4024034_0 PFAM regulator of chromosome condensation, RCC1 - - - 0.0000000000000000000000000000000003773 149.0
HFD2_k127_4024034_1 Glutamine amidotransferases class-II - - - 0.00000000000000000000008544 110.0
HFD2_k127_4026850_0 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005017 329.0
HFD2_k127_4026850_1 Belongs to the peptidase S16 family K01338,K04076 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000002486 214.0
HFD2_k127_4040999_0 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000001713 103.0
HFD2_k127_4040999_1 Belongs to the peptidase S8 family - - - 0.00000001937 59.0
HFD2_k127_4040999_2 Methyltransferase small domain - - - 0.000000382 58.0
HFD2_k127_4042453_0 Glycosyltransferase family 20 K00697 - 2.4.1.15,2.4.1.347 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 377.0
HFD2_k127_4042453_1 Serine aminopeptidase, S33 - - - 0.0000000000000000002817 92.0
HFD2_k127_4045059_0 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005266 278.0
HFD2_k127_4046215_0 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009289 317.0
HFD2_k127_4046215_1 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179,K17105 - 2.5.1.39,2.5.1.42 0.0000000000000000000000000000000000000001166 163.0
HFD2_k127_4046215_2 Diacylglycerol kinase catalytic domain - - - 0.000000000000000000000000000000000000001003 161.0
HFD2_k127_4054911_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000001277 211.0
HFD2_k127_4054911_1 - - - - 0.00000000000001344 85.0
HFD2_k127_4054911_3 domain, Protein K00573,K02335 - 2.1.1.77,2.7.7.7 0.0000002189 63.0
HFD2_k127_4056481_0 Putative aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009622 319.0
HFD2_k127_4056481_1 Stigma-specific protein, Stig1 - - - 0.00000000000000000000000000008245 128.0
HFD2_k127_4057683_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 354.0
HFD2_k127_4057683_1 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003733 260.0
HFD2_k127_4057911_0 - - - - 0.00000000000000000000000000000000000000000000000000000002577 213.0
HFD2_k127_4060171_0 Beta-Casp domain K07576 - - 0.000000000000000000000000000000000000000000000000000000000000001631 222.0
HFD2_k127_4060171_1 peptidase activity - - - 0.00000000000000000000000001608 124.0
HFD2_k127_4060171_2 Major facilitator Superfamily - - - 0.000000000000000007103 85.0
HFD2_k127_4063159_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000003947 202.0
HFD2_k127_4063159_1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 - - - 0.00000000000000000000000000000000004051 145.0
HFD2_k127_4064437_0 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005737 438.0
HFD2_k127_4064437_1 Protein of unknown function (DUF4240) - - - 0.000000000000000000000000000000000000000000000000000001331 198.0
HFD2_k127_4064437_2 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000007199 124.0
HFD2_k127_4064437_3 Transcriptional regulator - - - 0.00003064 52.0
HFD2_k127_4065021_0 of the major facilitator superfamily K08151 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007652 254.0
HFD2_k127_4065021_1 CAAX protease self-immunity - - - 0.00000000000000000000000000001412 124.0
HFD2_k127_4067089_0 AAA domain K07028 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007846 376.0
HFD2_k127_4070352_0 Glycosyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004296 299.0
HFD2_k127_4084268_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005073 259.0
HFD2_k127_4084268_1 serine threonine protein kinase K08282,K08884,K11916,K12132 - 2.7.11.1 0.0000000000000000000000000000000008572 140.0
HFD2_k127_4084268_2 sigma-54 factor, interaction domain-containing protein - - - 0.000706 49.0
HFD2_k127_4087919_0 cell adhesion involved in biofilm formation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 375.0
HFD2_k127_4087919_1 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005009 348.0
HFD2_k127_4090336_0 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K07712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 333.0
HFD2_k127_4090336_1 Beta-L-arabinofuranosidase, GH127 - - - 0.0000000928 65.0
HFD2_k127_4090336_2 Beta-L-arabinofuranosidase, GH127 - - - 0.0000002905 63.0
HFD2_k127_4092839_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002811 463.0
HFD2_k127_4092839_1 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00001341 53.0
HFD2_k127_4095594_0 Protein of unknown function (DUF523) K03783 - 2.4.2.1 0.0000000000000000002115 96.0
HFD2_k127_4095594_1 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000000000005041 78.0
HFD2_k127_4098565_0 Pfam Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000001555 216.0
HFD2_k127_4098565_1 COG0436 Aspartate tyrosine aromatic aminotransferase - - - 0.000000000000000000000000000006686 127.0
HFD2_k127_4098565_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000004466 121.0
HFD2_k127_4098565_3 COG1886 Flagellar motor switch type III secretory pathway protein K02416,K03225 - - 0.0000000000001191 83.0
HFD2_k127_4104265_0 PFAM NAD dependent epimerase dehydratase family K01709 - 4.2.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005902 513.0
HFD2_k127_4104265_1 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000000007072 189.0
HFD2_k127_4104265_2 Putative zinc binding domain - - - 0.0000000000000000000000000000000001321 139.0
HFD2_k127_4104265_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000007448 107.0
HFD2_k127_4106800_0 Bacterial regulatory proteins, tetR family K16137 - - 0.0000000000000000000000000000000000000000001862 167.0
HFD2_k127_4106800_1 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000001781 157.0
HFD2_k127_4106800_2 Thioesterase-like superfamily - - - 0.00000000000000657 81.0
HFD2_k127_4106800_3 lipolytic protein G-D-S-L family - - - 0.000000000005194 74.0
HFD2_k127_4107075_0 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002358 286.0
HFD2_k127_4107075_1 Belongs to the SUA5 family K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009193 276.0
HFD2_k127_4107075_2 Phosphomethylpyrimidine kinase K00868,K00941,K03147,K21219 GO:0008150,GO:0040007 2.5.1.3,2.7.1.35,2.7.1.49,2.7.4.7,4.1.99.17 0.000000000000000000000000000000000003139 147.0
HFD2_k127_4107075_3 Copper binding proteins, plastocyanin/azurin family - - - 0.000000000000004133 82.0
HFD2_k127_4107792_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008676 477.0
HFD2_k127_4107792_1 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000007804 243.0
HFD2_k127_4107792_2 aminopeptidase N - - - 0.00000000000000000000000000000000000000000000000008496 194.0
HFD2_k127_4107792_3 acetyltransferase involved in intracellular survival and related - - - 0.000000000000000000005431 107.0
HFD2_k127_4107792_4 GGDEF domain K03412,K03413 - 3.1.1.61,3.5.1.44 0.0000008828 58.0
HFD2_k127_4107792_5 Sulfatase K01133 - 3.1.6.6 0.000003874 59.0
HFD2_k127_4108151_0 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 300.0
HFD2_k127_4108151_1 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000000000001903 203.0
HFD2_k127_4108151_2 response regulator - - - 0.00000000000000000000000000000001389 132.0
HFD2_k127_4108151_3 Chemotaxis phosphatase CheX K03409 - - 0.000004765 56.0
HFD2_k127_4108441_0 transferase activity, transferring glycosyl groups K01371 - 3.4.22.38 0.0000000000000000000000000000000000000000000000001011 196.0
HFD2_k127_4108441_1 Transcription factor zinc-finger K09981 - - 0.000002478 59.0
HFD2_k127_4116348_0 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000001407 243.0
HFD2_k127_4116348_1 - - - - 0.000000000000000000002848 109.0
HFD2_k127_4116348_2 Concanavalin A-like lectin/glucanases superfamily - - - 0.000000000178 71.0
HFD2_k127_4116793_0 - - - - 0.00000000000000000000000003512 119.0
HFD2_k127_4116793_1 - - - - 0.000000000000000000000003255 117.0
HFD2_k127_4118416_0 Transcriptional regulator - - - 0.00000000000000000000000000001566 135.0
HFD2_k127_4118416_1 Methyltransferase domain - - - 0.000001864 56.0
HFD2_k127_412019_0 chlorophyll binding K02557,K03640,K12216 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 351.0
HFD2_k127_412019_1 PFAM glycoside hydrolase, family 18 - - - 0.0000000000000001162 92.0
HFD2_k127_412019_2 SMART protein phosphatase 2C domain protein - - - 0.0001752 49.0
HFD2_k127_4123357_0 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000000000000000004139 153.0
HFD2_k127_4123357_1 Bacterial capsule synthesis protein PGA_cap K06990,K07282 - - 0.0000000000000000000000000000000000008797 154.0
HFD2_k127_4123357_2 Extradiol ring-cleavage dioxygenase, class III - - - 0.000000008641 62.0
HFD2_k127_4129774_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 476.0
HFD2_k127_4129774_1 CAAX protease self-immunity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 364.0
HFD2_k127_4129802_0 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 309.0
HFD2_k127_4129802_1 Cytochrome P450 - - - 0.000000000000000000000007601 102.0
HFD2_k127_4135237_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1057.0
HFD2_k127_4135237_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000005443 227.0
HFD2_k127_4135237_2 Universal stress protein - - - 0.000000000000000000001228 102.0
HFD2_k127_4135237_3 - - - - 0.00000003936 61.0
HFD2_k127_4135237_4 Biopolymer transport protein ExbD/TolR K03559 - - 0.000169 53.0
HFD2_k127_4135237_5 Acetyl-coenzyme A transporter 1 - GO:0000295,GO:0003674,GO:0005215,GO:0005346,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006862,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0008521,GO:0015075,GO:0015077,GO:0015078,GO:0015215,GO:0015216,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015605,GO:0015672,GO:0015711,GO:0015748,GO:0015865,GO:0015868,GO:0015876,GO:0015916,GO:0015931,GO:0015932,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0035348,GO:0042886,GO:0042887,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051182,GO:0051184,GO:0051185,GO:0051234,GO:0051503,GO:0055085,GO:0071077,GO:0071106,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:0072530,GO:0098655,GO:0098656,GO:0098660,GO:0098662,GO:1901264,GO:1901337,GO:1901505,GO:1901679,GO:1901682,GO:1902600 - 0.0006968 44.0
HFD2_k127_4135956_0 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 603.0
HFD2_k127_4136183_0 OmpA family K03286 - - 0.00000000000007208 83.0
HFD2_k127_4143939_0 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 310.0
HFD2_k127_4143939_1 Aldo keto - - - 0.000000000000000000000000000000000000000000000000000000003577 203.0
HFD2_k127_4143939_2 Carboxyltransferase domain, subdomain A and B - - - 0.000000000000000000000000000000000009173 147.0
HFD2_k127_4146043_1 oligosaccharyl transferase activity - - - 0.00000000000000000000000003818 113.0
HFD2_k127_4148718_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000825 489.0
HFD2_k127_4148718_1 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001735 254.0
HFD2_k127_4148718_2 repeat protein - - - 0.00000000000000000000000000000000001199 146.0
HFD2_k127_4148718_3 Ribbon-helix-helix domain - - - 0.000000000000000000000008866 103.0
HFD2_k127_4150434_0 Acyl-CoA dehydrogenase, C-terminal domain K11731 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009946 295.0
HFD2_k127_4150434_1 Cytochrome c - - - 0.000000000000000000000000000000000000000000000001755 182.0
HFD2_k127_4157139_0 Two component regulator propeller - - - 2.312e-212 679.0
HFD2_k127_4157139_1 translation initiation factor activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004295 547.0
HFD2_k127_4157139_2 Family membership K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006954 291.0
HFD2_k127_4157139_3 UvrD/REP helicase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002659 270.0
HFD2_k127_4157139_4 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000001504 143.0
HFD2_k127_4157139_6 protein kinase activity - - - 0.000000000000005568 85.0
HFD2_k127_416162_0 Uracil phosphoribosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 390.0
HFD2_k127_416162_1 conserved protein (DUF2183) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003085 295.0
HFD2_k127_4167150_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000001823 222.0
HFD2_k127_4167150_1 WGR domain protein - - - 0.000000000000000000000000000000000000000000000000001099 199.0
HFD2_k127_417852_0 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 355.0
HFD2_k127_417852_1 - - - - 0.00000000000000000000000000007101 123.0
HFD2_k127_417852_2 OmpA family - - - 0.000000000000003444 87.0
HFD2_k127_4190178_0 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001414 266.0
HFD2_k127_4190178_1 Rieske 2Fe-2S K15982 GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0005506,GO:0006066,GO:0006629,GO:0006694,GO:0006706,GO:0006707,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008610,GO:0009056,GO:0009058,GO:0009405,GO:0009987,GO:0010033,GO:0014070,GO:0016042,GO:0016043,GO:0016125,GO:0016127,GO:0016491,GO:0016705,GO:0016709,GO:0022607,GO:0033993,GO:0036200,GO:0036314,GO:0042221,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044238,GO:0044281,GO:0044282,GO:0044419,GO:0046164,GO:0046872,GO:0046914,GO:0047086,GO:0048037,GO:0050292,GO:0050896,GO:0051259,GO:0051260,GO:0051536,GO:0051537,GO:0051540,GO:0051704,GO:0055114,GO:0065003,GO:0070206,GO:0070207,GO:0070723,GO:0071704,GO:0071840,GO:0097305,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1901700,GO:1902652 1.14.13.142 0.0000000000000000000000000000000002139 145.0
HFD2_k127_4192828_0 MCM2/3/5 family K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 407.0
HFD2_k127_4192828_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006056 348.0
HFD2_k127_4192828_3 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000009251 256.0
HFD2_k127_4194895_0 Mur ligase family, glutamate ligase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 332.0
HFD2_k127_4194895_1 GNAT family acetyltransferase K03802 - 6.3.2.29,6.3.2.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007883 281.0
HFD2_k127_4194895_2 Peptidase family M50 K06212,K06402 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000002176 166.0
HFD2_k127_4194895_3 Histidine kinase K15011 - 2.7.13.3 0.00000001625 63.0
HFD2_k127_4194895_4 Domain of unknown function (DU1801) - - - 0.0000002615 54.0
HFD2_k127_4196196_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002866 269.0
HFD2_k127_4196196_3 Kazal type serine protease inhibitors - - - 0.0003677 49.0
HFD2_k127_4200259_0 Histidine kinase K02490 - - 0.0000000000000000005382 98.0
HFD2_k127_4200259_1 Transcriptional regulator - - - 0.0000000000000004844 79.0
HFD2_k127_4200519_0 von Willebrand factor (vWF) type A domain - - - 1.211e-264 828.0
HFD2_k127_4200519_1 - - - - 0.0000005898 53.0
HFD2_k127_4200519_2 amine dehydrogenase activity - - - 0.00005352 53.0
HFD2_k127_4203867_0 DUF218 domain K03748 - - 0.00000000000000000000000000000000000000000000000009649 190.0
HFD2_k127_4203867_1 phosphatase K20074 - 3.1.3.16 0.00000000000000000001149 102.0
HFD2_k127_4204455_0 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 393.0
HFD2_k127_4204455_1 acid phosphatase activity K22390 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000003199 64.0
HFD2_k127_4222348_0 oxidoreductase activity K07114 - - 0.000000000000000000000000003466 124.0
HFD2_k127_4225975_0 repeat protein - - - 0.0 1236.0
HFD2_k127_4225975_1 - - - - 0.0001485 52.0
HFD2_k127_4233128_0 Putative glycosyl hydrolase domain - - - 0.0000000000000000000000000000000000000000000003736 184.0
HFD2_k127_4233128_1 Belongs to the ompA family K03640 - - 0.0000000001938 66.0
HFD2_k127_4233139_0 COG0277 FAD FMN-containing dehydrogenases - - - 2.869e-251 797.0
HFD2_k127_424525_0 domain protein K21147 - 2.7.7.80,2.8.1.11 2.524e-197 620.0
HFD2_k127_424525_1 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003279 297.0
HFD2_k127_424525_2 Peptidase M15 K02395 - - 0.0000000000000000000000000000000000000000000004461 176.0
HFD2_k127_4247288_0 Type IV pilus assembly protein PilM; K02461 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 392.0
HFD2_k127_4247288_1 Type II secretion system (T2SS), protein K K02460 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003031 361.0
HFD2_k127_4247288_3 - - - - 0.000000000000000000000000006062 120.0
HFD2_k127_4249404_0 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 375.0
HFD2_k127_4249404_1 - - - - 0.0000000000000000000000000000000000000000000008288 178.0
HFD2_k127_4249404_2 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000001807 148.0
HFD2_k127_425140_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000004277 243.0
HFD2_k127_4258099_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 2.293e-225 708.0
HFD2_k127_4258099_1 Asparaginase K13051 - 3.4.19.5 0.00000000000000000000000000001165 123.0
HFD2_k127_4258099_3 serine-type endopeptidase activity - - - 0.0000000000000001484 93.0
HFD2_k127_4261807_0 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007173 586.0
HFD2_k127_4261807_1 long-chain fatty acid transporting porin activity - - - 0.0000000000000001747 85.0
HFD2_k127_4268579_0 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K18331 - 1.12.1.3 0.000000000000000000000000000000000000000000000000000000000007902 222.0
HFD2_k127_4268579_1 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000006117 58.0
HFD2_k127_4269306_1 - - - - 0.000000000000000000000000000000001362 132.0
HFD2_k127_4269306_2 Belongs to the glycosyl hydrolase family 6 K10804 - 3.1.1.5 0.0000000000000001128 91.0
HFD2_k127_4270110_1 Esterase-like activity of phytase - - - 0.00006402 53.0
HFD2_k127_4273026_0 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 438.0
HFD2_k127_4273026_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 364.0
HFD2_k127_4273026_2 Cytochrome c - - - 0.00000000000000000000000000000001102 137.0
HFD2_k127_4273026_3 PFAM Rieske 2Fe-2S K02636 - 1.10.9.1 0.000000000000000000000001728 108.0
HFD2_k127_4278798_0 WGR domain protein - - - 0.000000000000000000000000102 116.0
HFD2_k127_4278798_1 - - - - 0.0000000000000000000000002844 113.0
HFD2_k127_4278798_2 ThiS family - - - 0.0000000000000000000006325 96.0
HFD2_k127_4282693_0 Rod shape-determining protein K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 543.0
HFD2_k127_4282693_1 PFAM RNP-1 like RNA-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006708 323.0
HFD2_k127_4282693_2 Histidine kinase - - - 0.000000000000000000000008698 107.0
HFD2_k127_4282693_3 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000000002018 85.0
HFD2_k127_4291700_0 COG1073 hydrolases of the alpha beta superfamily - - - 0.00000543 59.0
HFD2_k127_4295233_0 Lactonase, 7-bladed beta-propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000401 232.0
HFD2_k127_4295233_1 oxidoreductase activity K07114 - - 0.0000000000000005323 81.0
HFD2_k127_4314727_0 PFAM acyl-CoA dehydrogenase domain protein K00252 - 1.3.8.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006649 490.0
HFD2_k127_4314727_1 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.0000000000000000000000000000000000000000000000000000000000008214 220.0
HFD2_k127_4314727_2 membrane - - - 0.000000000001271 72.0
HFD2_k127_4315391_1 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.00000000000000000000000000000000000000000000000008407 188.0
HFD2_k127_4317104_0 AcrB/AcrD/AcrF family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004935 479.0
HFD2_k127_4317104_1 outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000007611 228.0
HFD2_k127_4317104_2 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000000000005097 199.0
HFD2_k127_4317764_0 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 396.0
HFD2_k127_4317764_1 Negative regulator of - - - 0.00000000000000000000000000000000000002341 162.0
HFD2_k127_4318862_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000003021 89.0
HFD2_k127_4319813_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 1.939e-195 628.0
HFD2_k127_4320654_0 Uncharacterised protein family (UPF0227) K07000 - - 0.000000000000000000000000000000000000000000000000000000000000000009674 234.0
HFD2_k127_4320654_1 rhamnose metabolic process - - - 0.00000000000000000000000003801 117.0
HFD2_k127_4322417_0 AI-2E family transporter - - - 0.0000000000000000000000000000003739 137.0
HFD2_k127_4322417_1 Permease MlaE K02066 - - 0.0000000000000002851 90.0
HFD2_k127_4325528_0 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005478 460.0
HFD2_k127_4325528_1 TIGRFAM efflux transporter, RND family, MFP subunit K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006553 318.0
HFD2_k127_4325528_2 CDP-alcohol phosphatidyltransferase K00995,K08744 - 2.7.8.41,2.7.8.5 0.000000000000000000000000000000004857 135.0
HFD2_k127_4325528_3 AMP binding - GO:0008150,GO:0040007 - 0.000000000000000006149 97.0
HFD2_k127_4339798_0 Pyruvate phosphate dikinase - - - 0.00000000000000000000000000000001383 136.0
HFD2_k127_4339798_1 Protein conserved in bacteria K09947 - - 0.000000000000000001859 93.0
HFD2_k127_4339798_2 amine dehydrogenase activity - - - 0.0000000000000001965 91.0
HFD2_k127_4339798_3 40-residue YVTN family beta-propeller repeat - - - 0.000443 52.0
HFD2_k127_4343486_0 DNA polymerase III K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000662 205.0
HFD2_k127_4343486_1 Metallo-beta-lactamase superfamily - - - 0.00001912 56.0
HFD2_k127_4343678_0 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 357.0
HFD2_k127_4343678_1 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000001727 119.0
HFD2_k127_4343678_2 CDP-archaeol synthase - - - 0.000000000005082 74.0
HFD2_k127_4346321_0 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000007768 241.0
HFD2_k127_4346321_1 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000000000000003166 153.0
HFD2_k127_4346321_2 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000006986 125.0
HFD2_k127_4346321_3 PBS lyase - - - 0.0000000000000000508 89.0
HFD2_k127_434762_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000005784 241.0
HFD2_k127_434762_1 cell adhesion K07093 - - 0.000000001009 69.0
HFD2_k127_4347718_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002192 273.0
HFD2_k127_4350097_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 415.0
HFD2_k127_4350097_1 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002904 280.0
HFD2_k127_4350097_2 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.00000000000000000000000002188 113.0
HFD2_k127_4350097_3 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.0000000000003313 73.0
HFD2_k127_435108_0 COG1233 Phytoene dehydrogenase and related - - - 0.00000000000000000000000002838 111.0
HFD2_k127_435108_1 Acetyltransferase (GNAT) domain - - - 0.0000000000001143 79.0
HFD2_k127_435108_2 Protein of unknown function (DUF3047) - - - 0.0000002808 60.0
HFD2_k127_4352467_0 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 431.0
HFD2_k127_4352467_1 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009018 340.0
HFD2_k127_4355320_1 - - - - 0.00000000000000000009772 97.0
HFD2_k127_436727_0 Thioredoxin-like - - - 0.000000000000000000000006612 113.0
HFD2_k127_4367729_0 3-demethylubiquinone-9 3-O-methyltransferase activity K11434,K19737 - 2.1.1.319,2.1.1.320 0.00000000000000000000000000000000000000000000000000006254 204.0
HFD2_k127_4367729_1 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000000000000000000001739 203.0
HFD2_k127_4367729_2 Preprotein translocase SecG subunit K03075 - - 0.0000000000000000000000000001321 120.0
HFD2_k127_4367729_3 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000001865 59.0
HFD2_k127_4371785_0 Belongs to the serpin family K13963 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005244 293.0
HFD2_k127_4371785_1 Domain of unknown function (DUF4340) - - - 0.000000000000000000000000000002516 125.0
HFD2_k127_4375514_0 Family membership K12132 - 2.7.11.1 0.000000000000000000000000002967 124.0
HFD2_k127_4378787_0 Amidohydrolase family K01466 - 3.5.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006134 300.0
HFD2_k127_4378787_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 297.0
HFD2_k127_4378787_2 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000006066 171.0
HFD2_k127_4380415_0 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000262 214.0
HFD2_k127_4380415_1 Periplasmic protein TonB links inner and outer membranes - - - 0.00000001025 66.0
HFD2_k127_4387618_0 TIGRFAM amino acid adenylation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 354.0
HFD2_k127_4387618_1 Non-ribosomal peptide synthetase modules and related proteins - - - 0.000000000000000000000000000003859 127.0
HFD2_k127_4387880_0 Ppx GppA K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002388 285.0
HFD2_k127_4387880_1 PFAM OmpA MotB domain protein K02557 - - 0.0000000000000000000000000000000000000000000000000000000000000005896 229.0
HFD2_k127_4390540_0 Belongs to the DNA photolyase family K01669 GO:0000003,GO:0000166,GO:0000719,GO:0001101,GO:0002252,GO:0002376,GO:0003006,GO:0003674,GO:0003824,GO:0003904,GO:0003913,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005773,GO:0006139,GO:0006259,GO:0006281,GO:0006290,GO:0006325,GO:0006338,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006874,GO:0006875,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0007154,GO:0007165,GO:0007275,GO:0007623,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009314,GO:0009414,GO:0009415,GO:0009416,GO:0009605,GO:0009606,GO:0009607,GO:0009615,GO:0009628,GO:0009637,GO:0009638,GO:0009642,GO:0009645,GO:0009646,GO:0009648,GO:0009719,GO:0009725,GO:0009785,GO:0009791,GO:0009881,GO:0009882,GO:0009888,GO:0009893,GO:0009909,GO:0009911,GO:0009987,GO:0010033,GO:0010035,GO:0010073,GO:0010075,GO:0010118,GO:0010228,GO:0010244,GO:0010617,GO:0014070,GO:0016043,GO:0016604,GO:0016829,GO:0016830,GO:0017076,GO:0019222,GO:0019637,GO:0019725,GO:0022414,GO:0022603,GO:0023052,GO:0030003,GO:0030522,GO:0030554,GO:0031323,GO:0031325,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0033993,GO:0034641,GO:0035639,GO:0036094,GO:0038023,GO:0040008,GO:0042221,GO:0042592,GO:0042726,GO:0042752,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044260,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0048037,GO:0048507,GO:0048509,GO:0048511,GO:0048518,GO:0048522,GO:0048571,GO:0048573,GO:0048574,GO:0048580,GO:0048582,GO:0048583,GO:0048608,GO:0048638,GO:0048731,GO:0048831,GO:0048856,GO:0048878,GO:0050660,GO:0050662,GO:0050789,GO:0050793,GO:0050794,GO:0050801,GO:0050896,GO:0051094,GO:0051186,GO:0051239,GO:0051240,GO:0051276,GO:0051480,GO:0051607,GO:0051704,GO:0051707,GO:0051716,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055086,GO:0060089,GO:0061458,GO:0065007,GO:0065008,GO:0070013,GO:0071214,GO:0071478,GO:0071482,GO:0071483,GO:0071704,GO:0071840,GO:0071949,GO:0072387,GO:0072503,GO:0072507,GO:0090304,GO:0097159,GO:0097367,GO:0098542,GO:0098771,GO:0104004,GO:0140097,GO:1900618,GO:1901265,GO:1901360,GO:1901363,GO:1901371,GO:1901564,GO:1901700,GO:1902347,GO:1905421,GO:2000024,GO:2000026,GO:2000028,GO:2000241,GO:2000243,GO:2000377,GO:2000379 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 342.0
HFD2_k127_4390540_1 Flavin-binding monooxygenase-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003412 260.0
HFD2_k127_4390540_2 - - - - 0.0000339 55.0
HFD2_k127_4396230_0 Non-ribosomal peptide synthetase modules and related - - - 1.15e-259 831.0
HFD2_k127_4403899_0 Belongs to the glycosyl hydrolase 31 family K01811,K15922 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006790,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016787,GO:0016798,GO:0019637,GO:0034308,GO:0042180,GO:0044237,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0061720,GO:0071704,GO:1901135,GO:1901136,GO:1901575,GO:1901615,GO:1902776,GO:1902777,GO:1990929 3.2.1.177,3.2.1.199 0.00000000000000001381 88.0
HFD2_k127_4404283_0 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 400.0
HFD2_k127_4404283_1 acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 382.0
HFD2_k127_4404283_2 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000002081 203.0
HFD2_k127_4404283_3 - - - - 0.0000000000000000000000000000000001192 149.0
HFD2_k127_4404677_0 OPT oligopeptide transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 415.0
HFD2_k127_4404677_1 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001344 240.0
HFD2_k127_4404677_3 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000003761 55.0
HFD2_k127_4404677_4 SMART Transport-associated and nodulation region - - - 0.0001857 51.0
HFD2_k127_4405266_0 phosphoesterases, related to the Icc protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008219 313.0
HFD2_k127_4405266_3 Esterase, PHB depolymerase family - - - 0.000488 48.0
HFD2_k127_440768_0 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005237 579.0
HFD2_k127_4417155_0 twitching motility protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 420.0
HFD2_k127_4417155_1 beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 387.0
HFD2_k127_4417155_2 GAF domain - - - 0.000000000000000000000000000000000000000000000000000001478 199.0
HFD2_k127_4417155_3 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000009883 161.0
HFD2_k127_4417155_4 response regulator - - - 0.000009186 53.0
HFD2_k127_4421275_0 aldehyde-lyase activity K01621 - 4.1.2.22,4.1.2.9 0.0 1313.0
HFD2_k127_4421275_1 alpha-glucan phosphorylase K00688 - 2.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 360.0
HFD2_k127_4421275_2 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.000002983 57.0
HFD2_k127_4422599_0 PFAM Methylmalonyl-CoA mutase K01848 - 5.4.99.2 3.885e-219 693.0
HFD2_k127_4422599_1 Ribose-phosphate pyrophosphokinase K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004789 348.0
HFD2_k127_4425685_0 Family membership K08884 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004818 344.0
HFD2_k127_4425685_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000003857 111.0
HFD2_k127_4425685_2 Conserved Protein - - - 0.00000000001153 73.0
HFD2_k127_4431221_0 non-ribosomal peptide synthetase - - - 0.0 1542.0
HFD2_k127_4431221_1 synthase - - - 8.163e-277 880.0
HFD2_k127_4431221_2 thioesterase involved in non-ribosomal peptide biosynthesis K01071 - 3.1.2.21 0.00000000000000000000000000000000000000000000000000002233 201.0
HFD2_k127_4433386_0 Glycoside-hydrolase family GH114 K01884 - 6.1.1.16 0.00000000000000000129 94.0
HFD2_k127_4433386_1 Polysaccharide deacetylase K22278 - 3.5.1.104 0.0000000000000003502 91.0
HFD2_k127_4433386_2 Concanavalin A-like lectin/glucanases superfamily - - - 0.0000008574 60.0
HFD2_k127_4442835_0 cheY-homologous receiver domain - - - 0.000000000000000264 85.0
HFD2_k127_4442835_1 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K01179,K03832 - 3.2.1.4 0.00000005426 64.0
HFD2_k127_4446459_1 Histone deacetylase domain - - - 0.0000000000000000000000000000000000001417 149.0
HFD2_k127_4446459_2 lyase activity - - - 0.000000000000000000000000000000132 128.0
HFD2_k127_4469017_1 protein phosphatase 2C domain protein K01090,K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000006172 229.0
HFD2_k127_4469017_2 CsbD-like - - - 0.00000000000000000000005162 101.0
HFD2_k127_4469017_3 Domain of unknown function (DUF4398) - - - 0.00000000000003306 78.0
HFD2_k127_4469017_4 Domain of unknown function (DUF4398) - - - 0.000000001184 66.0
HFD2_k127_4469017_5 -O-antigen K02847 - - 0.000002605 59.0
HFD2_k127_4471146_0 Peptidase family M23 K21471 - - 0.000000000000000000000000000000000000000000000000000000000000000003887 242.0
HFD2_k127_4471146_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000001381 218.0
HFD2_k127_4471146_3 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000000000008197 85.0
HFD2_k127_4471909_0 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000001942 132.0
HFD2_k127_4473823_0 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000002826 217.0
HFD2_k127_4473823_1 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000008157 132.0
HFD2_k127_4473823_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000005352 65.0
HFD2_k127_4480907_0 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000004515 147.0
HFD2_k127_450464_0 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000001259 60.0
HFD2_k127_4505378_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 560.0
HFD2_k127_4505378_1 nucleotide metabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 292.0
HFD2_k127_4505378_3 phosphohistidine phosphatase, SixA K08296 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0071704,GO:1901564 - 0.00000000000000002105 89.0
HFD2_k127_4505378_4 Thioredoxin - - - 0.0002962 49.0
HFD2_k127_4511471_0 DnaJ molecular chaperone homology domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008031 372.0
HFD2_k127_4511471_1 protein kinase activity - - - 0.00000000000000000000001504 110.0
HFD2_k127_451190_0 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005817 348.0
HFD2_k127_451190_1 TIGRFAM Amino acid adenylation - - - 0.0000000000000000000000000000000000000000000000000000000000000297 241.0
HFD2_k127_451190_2 Fatty acid hydroxylase superfamily - - - 0.000003497 51.0
HFD2_k127_4514281_0 Family membership K08884 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000255 287.0
HFD2_k127_4514281_1 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001097 266.0
HFD2_k127_4518862_0 protein kinase activity K08884 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 368.0
HFD2_k127_4518862_2 - - - - 0.00000005679 63.0
HFD2_k127_4525945_0 Linear gramicidin synthase subunit K02364 - 6.3.2.14 0.0000000000000000000000000000000000000000000000001486 196.0
HFD2_k127_4525945_1 Site-specific recombinase - - - 0.00000000000000000000008761 108.0
HFD2_k127_4527305_0 Tex-like protein N-terminal domain K06959 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 399.0
HFD2_k127_4527305_1 GMC oxidoreductase K03333 - 1.1.3.6 0.000000000000000000000000000000000000000000000000007885 188.0
HFD2_k127_4530538_0 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000001082 143.0
HFD2_k127_4530538_1 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000001365 103.0
HFD2_k127_4531969_0 regulation of response to stimulus - - - 0.0000002196 63.0
HFD2_k127_453332_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007288 362.0
HFD2_k127_453332_1 - - - - 0.000000000003674 70.0
HFD2_k127_453332_2 - - - - 0.000000001453 63.0
HFD2_k127_4534318_0 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 471.0
HFD2_k127_4541533_0 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 286.0
HFD2_k127_4541533_1 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000562 173.0
HFD2_k127_4541533_2 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000194 102.0
HFD2_k127_4541533_3 ABC-type glycine betaine transport system K05845,K05846 - - 0.00000002521 56.0
HFD2_k127_4543412_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005382 374.0
HFD2_k127_4543412_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006792 346.0
HFD2_k127_4543962_0 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 1.109e-237 749.0
HFD2_k127_4543962_1 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000001454 172.0
HFD2_k127_4543962_2 Belongs to the glycosyl hydrolase 26 family K01218,K19355 - 3.2.1.78 0.000000000000000000000000000000000000000000008249 179.0
HFD2_k127_4544559_0 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000000000000000000000000711 162.0
HFD2_k127_4544559_1 Vault protein inter-alpha-trypsin domain - - - 0.0004507 52.0
HFD2_k127_4545563_0 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009187 258.0
HFD2_k127_4545563_1 protein involved in exopolysaccharide biosynthesis - - - 0.000000000000000000000000000000000000000000000000000002252 210.0
HFD2_k127_4546888_0 Protein of unknown function, DUF255 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 402.0
HFD2_k127_4546888_1 PFAM ABC transporter related K15738 - - 0.000000000000000000001933 98.0
HFD2_k127_4548609_0 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 413.0
HFD2_k127_4548609_1 TonB dependent receptor - - - 0.0000000000002412 77.0
HFD2_k127_4548673_0 TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family K02029,K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 389.0
HFD2_k127_4548673_1 ABC-type polar amino acid transport system ATPase component K02028 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000006123 239.0
HFD2_k127_4548673_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821,K03918,K07250,K13524 - 2.6.1.11,2.6.1.17,2.6.1.19,2.6.1.22,2.6.1.36 0.000000000000000000000004461 105.0
HFD2_k127_456055_0 ABC transporter transmembrane region K06147,K18890 - - 8.413e-209 666.0
HFD2_k127_456055_1 ABC transporter K06147,K18889 - - 1.381e-202 643.0
HFD2_k127_4562783_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000006328 221.0
HFD2_k127_4562783_1 - - - - 0.0000000000000000005736 89.0
HFD2_k127_4570819_1 transcriptional regulator - - - 0.0000000000000000000002658 102.0
HFD2_k127_4573898_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006817 542.0
HFD2_k127_4577157_0 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007319 523.0
HFD2_k127_4578255_0 DUF3160 - - - 0.000000000000000000000000000000001219 149.0
HFD2_k127_4579511_0 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 316.0
HFD2_k127_4579511_1 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002636 306.0
HFD2_k127_4579511_2 Phosphocarrier protein HPR K11189 - - 0.00000000000000000000000000356 113.0
HFD2_k127_4579511_3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.000001232 58.0
HFD2_k127_4588035_0 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000004305 220.0
HFD2_k127_4588035_1 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000006241 103.0
HFD2_k127_4603241_0 Belongs to the 5'-nucleotidase family K01081 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000123 267.0
HFD2_k127_4608325_0 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002941 272.0
HFD2_k127_4613159_0 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 382.0
HFD2_k127_4613159_1 Family membership K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000005815 248.0
HFD2_k127_4613159_2 PEGA domain - - - 0.00000000000000000000001019 110.0
HFD2_k127_4614102_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000003978 212.0
HFD2_k127_4614102_1 Sulfatase-modifying factor enzyme 1 - - - 0.0000001675 57.0
HFD2_k127_4614148_0 Domain of unknown function (DUF2383) - - - 0.0000000000000000000000000000000000000000000007078 169.0
HFD2_k127_4614148_1 energy transducer activity K03832 - - 0.0000000002033 73.0
HFD2_k127_4623228_0 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000007649 184.0
HFD2_k127_4626481_0 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000001557 262.0
HFD2_k127_4626481_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000006614 56.0
HFD2_k127_4628760_0 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004886 501.0
HFD2_k127_4628760_1 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004802 297.0
HFD2_k127_4631843_0 Serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.00000000000000000000000000000000001303 151.0
HFD2_k127_4631843_1 DnaJ molecular chaperone homology domain - - - 0.00000000000003996 85.0
HFD2_k127_4631843_2 Conserved repeat domain - - - 0.00001771 48.0
HFD2_k127_4635297_0 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K07712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009569 250.0
HFD2_k127_4636136_0 O-Antigen ligase - - - 0.0000000000000000000000000000000000000000000000000000000035 216.0
HFD2_k127_4636136_1 Carbohydrate family 9 binding domain-like - - - 0.000000000000000000418 90.0
HFD2_k127_4636136_2 Transglutaminase-like superfamily - - - 0.0004041 52.0
HFD2_k127_464257_0 - - - - 0.000000000001493 77.0
HFD2_k127_464257_1 - - - - 0.0009559 51.0
HFD2_k127_4644267_0 phosphorelay signal transduction system K10941 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 303.0
HFD2_k127_4644267_1 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.0000000000000000000000000000000000000000000000000000000000000002898 226.0
HFD2_k127_464883_0 PEGA domain K02014 - - 3.628e-271 865.0
HFD2_k127_464883_1 Family membership K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001611 291.0
HFD2_k127_464883_2 Family membership K08884 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000004717 259.0
HFD2_k127_464883_3 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000001226 181.0
HFD2_k127_464883_4 - - - - 0.00000000000000000000000000000001654 143.0
HFD2_k127_464883_5 Polysaccharide deacetylase K01452,K14659,K22278 - 3.5.1.104,3.5.1.41 0.00000000000000006828 93.0
HFD2_k127_4652417_0 Surface antigen K07277,K07278 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 432.0
HFD2_k127_4652417_1 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000000000000437 76.0
HFD2_k127_4652417_2 YXWGXW repeat (2 copies) - - - 0.000001106 60.0
HFD2_k127_4652417_3 RecA-superfamily ATPase possibly involved in signal transduction K08482 - - 0.00003577 55.0
HFD2_k127_4665055_0 GMC oxidoreductase K03333 - 1.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 564.0
HFD2_k127_4665055_1 FAD linked oxidase domain protein - - - 0.0000000000000000000000000000000000000003926 158.0
HFD2_k127_4665055_2 GMC oxidoreductase K03333 - 1.1.3.6 0.000000000000000003322 93.0
HFD2_k127_4665055_3 amine dehydrogenase activity - - - 0.000006062 57.0
HFD2_k127_4666800_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000001807 178.0
HFD2_k127_4666800_1 cell envelope organization K05807,K08309 - - 0.000000000000000000005431 107.0
HFD2_k127_4666800_2 Protein of unknown function (DUF1566) - - - 0.000000001158 67.0
HFD2_k127_466980_0 Forkhead associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004192 369.0
HFD2_k127_466980_1 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 362.0
HFD2_k127_466980_3 Mycolic acid cyclopropane synthetase - - - 0.000000000000000001408 87.0
HFD2_k127_4676124_2 ABC transporter K06147,K18889 - - 0.0005464 46.0
HFD2_k127_4680918_0 Heat shock 70 kDa protein K04043 - - 3.854e-252 784.0
HFD2_k127_4680918_1 Nicotinate phosphoribosyltransferase (NAPRTase) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 488.0
HFD2_k127_4680918_2 ABC transporter, ATP-binding protein K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006991 376.0
HFD2_k127_4680918_3 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000001005 151.0
HFD2_k127_4680918_4 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000716 126.0
HFD2_k127_468174_0 DnaJ molecular chaperone homology domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000119 278.0
HFD2_k127_468174_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K00082,K11752,K14652 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009451,GO:0009987,GO:0016070,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0034641,GO:0036094,GO:0042364,GO:0042726,GO:0042727,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046983,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.193,3.5.4.25,3.5.4.26,4.1.99.12 0.0000000000000000000000000000000000001795 146.0
HFD2_k127_4683625_0 response regulator K10943 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 517.0
HFD2_k127_4683625_1 His Kinase A (phosphoacceptor) domain K07709 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000004234 226.0
HFD2_k127_4691398_0 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005282 271.0
HFD2_k127_4691398_1 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.000000000000000000000000000000000000000000000000000001446 201.0
HFD2_k127_4691398_2 - - - - 0.00000000000000000000000000000000000001042 155.0
HFD2_k127_4691398_3 Biotin-lipoyl like - - - 0.00000000000000000000001042 104.0
HFD2_k127_4695046_0 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001347 262.0
HFD2_k127_4695046_1 FmdE, Molybdenum formylmethanofuran dehydrogenase operon - - - 0.00000000000000000000000000000000000000000001427 171.0
HFD2_k127_4695046_3 peroxidase activity K00435 - - 0.00000000008108 62.0
HFD2_k127_4701716_0 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000002047 144.0
HFD2_k127_4701716_1 His Kinase A (phosphoacceptor) domain K02484 - 2.7.13.3 0.000001166 50.0
HFD2_k127_4707059_0 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000000000005058 162.0
HFD2_k127_4707059_2 Predicted membrane protein (DUF2085) - - - 0.00003576 52.0
HFD2_k127_4712284_0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 397.0
HFD2_k127_4713133_0 PFAM NADH ubiquinone oxidoreductase, 20 Kd subunit K06282 - 1.12.99.6 6.366e-196 614.0
HFD2_k127_4713133_1 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 375.0
HFD2_k127_4714208_0 phosphorelay signal transduction system K01768,K10941,K11894 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 349.0
HFD2_k127_4714208_1 Calcium ion binding - GO:0002009,GO:0002165,GO:0003674,GO:0005198,GO:0005201,GO:0005575,GO:0005576,GO:0007275,GO:0007424,GO:0007444,GO:0007472,GO:0007475,GO:0007476,GO:0007552,GO:0007560,GO:0007591,GO:0008150,GO:0008362,GO:0008587,GO:0009653,GO:0009791,GO:0009886,GO:0009887,GO:0009888,GO:0022404,GO:0031012,GO:0032501,GO:0032502,GO:0035107,GO:0035114,GO:0035120,GO:0035220,GO:0035239,GO:0035295,GO:0040003,GO:0040005,GO:0042303,GO:0042335,GO:0044421,GO:0044719,GO:0048513,GO:0048563,GO:0048569,GO:0048707,GO:0048729,GO:0048731,GO:0048736,GO:0048737,GO:0048856,GO:0060429,GO:0060541,GO:0060562,GO:0065007,GO:0065008,GO:0090066 - 0.0008326 44.0
HFD2_k127_4715152_0 Peptidase S46 - - - 6.433e-243 773.0
HFD2_k127_472223_0 DNA helicase K03654 - 3.6.4.12 7.949e-208 675.0
HFD2_k127_472223_1 TonB-dependent Receptor Plug Domain - - - 4.139e-202 659.0
HFD2_k127_472223_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 383.0
HFD2_k127_472223_3 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004004 374.0
HFD2_k127_472223_4 Aminotransferase K11358 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 362.0
HFD2_k127_472223_5 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000007243 250.0
HFD2_k127_4728059_0 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 385.0
HFD2_k127_4728059_1 phospholipase C K01114 - 3.1.4.3 0.00000000000000000000000000000000000000000001538 168.0
HFD2_k127_4729724_0 Pfam:RRM_6 - - - 0.000000000000000000000000000000002942 132.0
HFD2_k127_4729724_1 - - - - 0.000001564 59.0
HFD2_k127_4737207_0 Glycosyl transferases group 1 K13668 - 2.4.1.346 0.00000000000000000000000000000000003618 156.0
HFD2_k127_4737207_1 glycosyl transferase - - - 0.00000002176 63.0
HFD2_k127_4751574_0 Protein of unknown function (DUF3570) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004159 327.0
HFD2_k127_4751574_2 - - - - 0.00007829 52.0
HFD2_k127_4766071_0 KR domain - - - 0.00000000000000000000000000000000000000000001315 173.0
HFD2_k127_4766071_1 Bacterial regulatory proteins, tetR family - - - 0.0001992 50.0
HFD2_k127_4772108_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007382 412.0
HFD2_k127_4772108_1 MoeA C-terminal region (domain IV) K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 367.0
HFD2_k127_4772108_2 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 321.0
HFD2_k127_4772108_3 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000006351 205.0
HFD2_k127_4772108_4 PFAM regulator of chromosome condensation, RCC1 - - - 0.0000000000000000000000000000000000000000000079 180.0
HFD2_k127_4772108_5 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.000000000000000000000000000000000000000004655 162.0
HFD2_k127_4772108_6 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000007289 157.0
HFD2_k127_4772108_7 PFAM Endonuclease Exonuclease phosphatase - - - 0.000000000000000000000000000000001792 141.0
HFD2_k127_4772108_8 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.00000000239 62.0
HFD2_k127_4774946_0 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005445 574.0
HFD2_k127_4774946_1 succinylglutamate desuccinylase activity K05526 - 3.5.1.96 0.00000000000000000000000000000000000000000000000000000000000000000006961 246.0
HFD2_k127_4774946_2 Putative esterase - - - 0.0000000000000000000000000000000000000000001393 164.0
HFD2_k127_4778103_0 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000007166 278.0
HFD2_k127_4778103_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000005958 74.0
HFD2_k127_4778657_0 Fatty acid hydroxylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007448 248.0
HFD2_k127_4778657_1 zinc-ribbon domain - - - 0.0000000000004929 73.0
HFD2_k127_4778657_2 COG1846 Transcriptional regulators - - - 0.00006586 51.0
HFD2_k127_4785331_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004912 569.0
HFD2_k127_4785331_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K15372 - 2.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 410.0
HFD2_k127_4789505_0 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005559 342.0
HFD2_k127_4789505_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000001066 172.0
HFD2_k127_4789505_2 protein kinase activity - - - 0.00000000003707 76.0
HFD2_k127_4792415_0 Zinc-dependent metalloprotease - - - 0.0000000000000000000000000000006355 132.0
HFD2_k127_4794483_0 Domain of unknown function (DUF1732) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001289 268.0
HFD2_k127_4794483_1 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000002842 261.0
HFD2_k127_4794483_2 Protein of unknown function (DUF507) K09804 - - 0.000000000000000000000000001689 113.0
HFD2_k127_4794483_3 Cytochrome c - - - 0.00000111 51.0
HFD2_k127_4795326_0 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000034 228.0
HFD2_k127_4795326_1 PHP domain protein - - - 0.000000000000000000000000000000000000001288 170.0
HFD2_k127_4795326_2 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000008008 138.0
HFD2_k127_4795326_3 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000000001924 129.0
HFD2_k127_4796164_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000001658 207.0
HFD2_k127_4796164_3 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000331 111.0
HFD2_k127_4796164_4 Bacterial transferase hexapeptide (six repeats) - - - 0.00004913 47.0
HFD2_k127_4804348_0 depolymerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000198 239.0
HFD2_k127_4804348_1 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.00000000000000000000000008467 120.0
HFD2_k127_4804348_2 Right handed beta helix region - - - 0.0003926 53.0
HFD2_k127_4805838_0 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 324.0
HFD2_k127_4805838_1 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000003543 209.0
HFD2_k127_4805838_2 Protein tyrosine kinase K08282 - 2.7.11.1 0.0000000000005495 71.0
HFD2_k127_4805838_3 PFAM Protein kinase domain K08309 - - 0.0000000003369 72.0
HFD2_k127_4810318_0 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002616 429.0
HFD2_k127_4810318_2 - - - - 0.0000000000000000000007265 104.0
HFD2_k127_4816189_0 Thioredoxin-like - - - 0.00000000000000000000000000000000000000003474 159.0
HFD2_k127_4816189_1 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol - - - 0.00000000000000000000000000001785 130.0
HFD2_k127_4816189_2 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000006112 93.0
HFD2_k127_4816189_3 Protein of unknown function (DUF420) K08976 - - 0.00000000005891 63.0
HFD2_k127_4816839_0 ATPase P-type (Transporting), HAD superfamily, subfamily IC K01535,K01537 - 3.6.3.6,3.6.3.8 8.53e-271 858.0
HFD2_k127_4816839_1 Nitrite reductase K00368,K08100 - 1.3.3.5,1.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009105 271.0
HFD2_k127_4816839_2 NnrS protein K07234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002374 262.0
HFD2_k127_4821676_0 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01738,K01883,K12339 - 2.5.1.47,6.1.1.16 0.000000000000000000000000000000000000000000000000000001107 193.0
HFD2_k127_4821676_1 pyrroloquinoline quinone binding - - - 0.00000000000000000000000000000000000000000000000000000186 206.0
HFD2_k127_4821676_2 proteolysis K21140,K21147 - 2.7.7.80,2.8.1.11,3.13.1.6 0.0000000000000000000000000000000000000000005019 163.0
HFD2_k127_4821734_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 404.0
HFD2_k127_4821734_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 336.0
HFD2_k127_4821734_2 PFAM phospholipase Carboxylesterase K06999 - - 0.0003048 51.0
HFD2_k127_483082_0 Periplasmic protein TonB links inner and outer membranes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009797 290.0
HFD2_k127_483082_1 Protein conserved in bacteria - - - 0.0000002198 59.0
HFD2_k127_483189_0 MMPL family K07003 - - 7.41e-200 642.0
HFD2_k127_483189_1 MMPL family K07003 - - 0.000000000000000000000000000000000000007054 151.0
HFD2_k127_483189_2 Di-iron-containing protein involved in the repair of iron-sulfur clusters - - - 0.0002412 49.0
HFD2_k127_4832141_0 thiolester hydrolase activity - - - 0.00001053 59.0
HFD2_k127_4834080_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000114 244.0
HFD2_k127_4834080_1 Serine/Threonine protein kinases, catalytic domain K12132 - 2.7.11.1 0.000000002575 70.0
HFD2_k127_4835945_0 homogentisate 12-dioxygenase K00451 - 1.13.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 310.0
HFD2_k127_4840578_0 Polysaccharide deacetylase - - - 0.000000001414 67.0
HFD2_k127_4840578_1 Belongs to the ompA family K03640 - - 0.000000003813 67.0
HFD2_k127_4841534_0 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002372 288.0
HFD2_k127_4841534_1 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000009137 197.0
HFD2_k127_4841534_2 Heavy metal translocating P-type atpase K01533,K17686 - 3.6.3.4,3.6.3.54 0.0000000004828 71.0
HFD2_k127_4849886_0 Belongs to the transketolase family K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006399 318.0
HFD2_k127_4849886_1 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000004885 106.0
HFD2_k127_4852338_0 Protein kinase domain K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000002759 253.0
HFD2_k127_4857208_0 Vault protein inter-alpha-trypsin domain - - - 0.000000000000000000000000000000000000000000000000000000000000001197 228.0
HFD2_k127_4857208_1 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0001375 53.0
HFD2_k127_4858703_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000004938 215.0
HFD2_k127_4859769_0 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00005689 52.0
HFD2_k127_4859769_1 PFAM Protein kinase domain K08309 - - 0.0005168 51.0
HFD2_k127_486231_0 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000495 203.0
HFD2_k127_486231_1 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000001276 143.0
HFD2_k127_486231_2 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06137 - 1.3.3.11 0.000000000000000000000005833 116.0
HFD2_k127_4862480_0 Mycolic acid cyclopropane synthetase K00574,K20238 - 2.1.1.317,2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 441.0
HFD2_k127_4862480_1 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009401 401.0
HFD2_k127_4862480_2 PFAM Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005385 411.0
HFD2_k127_4862480_3 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 347.0
HFD2_k127_4862480_4 Family membership - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004551 313.0
HFD2_k127_4862480_5 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000001965 190.0
HFD2_k127_4862480_6 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000012 164.0
HFD2_k127_4862480_7 Thioesterase superfamily - - - 0.000000000000000000004687 100.0
HFD2_k127_4863519_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 8.082e-212 674.0
HFD2_k127_4864973_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005531 277.0
HFD2_k127_4864973_1 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000357 145.0
HFD2_k127_4865752_0 PFAM Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000602 285.0
HFD2_k127_4865752_1 pseudouridine synthase activity K06178,K06183,K07058 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.22 0.0000000000000000000000000000000001585 151.0
HFD2_k127_4881619_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000536 438.0
HFD2_k127_4881619_1 - - - - 0.00000000000000000000000000000000000000000001089 176.0
HFD2_k127_4882366_0 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008575 334.0
HFD2_k127_4882366_1 response regulator K07712 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000008209 161.0
HFD2_k127_4882366_2 PHP domain protein K07053 - 3.1.3.97 0.00000000000000000000000000004777 136.0
HFD2_k127_4893139_0 protein kinase activity K08884 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000001276 241.0
HFD2_k127_4893139_1 response regulator - - - 0.000000000000000000000000000004239 138.0
HFD2_k127_4893139_2 Phytochelatin synthase - - - 0.0000000000174 64.0
HFD2_k127_4893139_3 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.000000001281 59.0
HFD2_k127_4902814_0 Lipopolysaccharide kinase (Kdo/WaaP) family K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005209 359.0
HFD2_k127_4902814_1 ThiJ/PfpI family-like K05520 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 332.0
HFD2_k127_4902814_2 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.000000000000000000000000000000000000000000000000000000001522 203.0
HFD2_k127_4902814_3 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000000001449 193.0
HFD2_k127_4903476_0 Dehydrogenase K19049 - 4.2.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004838 335.0
HFD2_k127_4903476_1 Sporulation protein YtfJ - - - 0.00000362 54.0
HFD2_k127_4903476_2 Dehydrogenase K19049 - 4.2.2.5 0.0006651 42.0
HFD2_k127_4904431_0 Alpha beta hydrolase - - - 0.0000000000000000000001838 113.0
HFD2_k127_4904431_1 Transcriptional regulator - - - 0.0000000000000001348 94.0
HFD2_k127_4904431_2 belongs to the glycosyl hydrolase 13 family K01176,K01208 GO:0005575,GO:0005576 3.2.1.1,3.2.1.133,3.2.1.135,3.2.1.54 0.000005218 54.0
HFD2_k127_4913676_0 arylsulfatase activity - - - 0.0000000000000000000000000005584 131.0
HFD2_k127_4913676_1 TIGRFAM repeat-companion domain TIGR02996 - - - 0.000000000004889 73.0
HFD2_k127_4917092_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000001093 219.0
HFD2_k127_4921585_0 response regulator K02481,K07713 - - 3.674e-210 661.0
HFD2_k127_4921585_1 E1-E2 ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 0.000000004147 63.0
HFD2_k127_4921585_2 Signal transduction histidine kinase, nitrogen specific K07708 - 2.7.13.3 0.00001821 46.0
HFD2_k127_4924891_1 Uncharacterized protein conserved in bacteria (DUF2064) - - - 0.00008318 53.0
HFD2_k127_4925112_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000000000000000000000000000000009911 149.0
HFD2_k127_4931903_0 Belongs to the glycosyl hydrolase 31 family K01187 - 3.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008821 499.0
HFD2_k127_4931903_2 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0004395 45.0
HFD2_k127_4932435_0 phosphorelay signal transduction system K01768,K10941,K11894 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 481.0
HFD2_k127_4932435_1 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000008571 254.0
HFD2_k127_4933374_0 NUDIX domain - - - 0.00000000000000000000000000000000000002956 149.0
HFD2_k127_4933374_1 Protein kinase domain K08884,K12132 - 2.7.11.1 0.0000000000000000000000001364 120.0
HFD2_k127_4933374_2 - - - - 0.00000000000001021 83.0
HFD2_k127_4933374_3 Ferredoxin, 2Fe-2S - - - 0.000005196 57.0
HFD2_k127_4936602_0 Sugar (and other) transporter K08151 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 435.0
HFD2_k127_4936602_1 deaminated base DNA N-glycosylase activity K03648 GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 0.0000000000000000000000000000000000000000000000000003849 188.0
HFD2_k127_4936602_2 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000004216 164.0
HFD2_k127_493702_0 Family membership K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000005512 241.0
HFD2_k127_493702_1 pseudouridine synthase activity K06178,K06183,K07058 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.22 0.000000000000000000000000000000000000000000000000001321 198.0
HFD2_k127_4937524_0 ABC transporter K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 372.0
HFD2_k127_4937524_1 transferase activity, transferring glycosyl groups K01365,K14475 - 3.4.22.15 0.0000000000000000000000000000000000000000000000000000000008016 224.0
HFD2_k127_4937524_2 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000000000001057 97.0
HFD2_k127_4940438_0 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000003167 92.0
HFD2_k127_4940438_1 gluconokinase activity - - - 0.000005312 50.0
HFD2_k127_4940438_2 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0005371 47.0
HFD2_k127_4941229_0 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005292 320.0
HFD2_k127_4941229_1 MlaD protein K06192 - - 0.00000000000000000000000001078 115.0
HFD2_k127_4941229_5 Domain of unknown function (DUF4870) K09940 - - 0.00003375 50.0
HFD2_k127_4943111_1 FG-GAP repeat - - - 0.0000000000009278 81.0
HFD2_k127_4945529_0 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) K08680 - 4.2.99.20 0.00000000000000000000000000000000002042 147.0
HFD2_k127_4945529_1 cheY-homologous receiver domain - - - 0.000000000000000000000000000000553 136.0
HFD2_k127_4945529_2 Leucine carboxyl methyltransferase - - - 0.00000000000000000000001809 111.0
HFD2_k127_4945529_3 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.0000000000000000399 85.0
HFD2_k127_4945529_4 PFAM Protein kinase domain K12132 - 2.7.11.1 0.0001562 45.0
HFD2_k127_4946370_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 347.0
HFD2_k127_4949406_0 Periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004811 279.0
HFD2_k127_4949406_1 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000001687 261.0
HFD2_k127_4949406_2 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.000000001829 70.0
HFD2_k127_4953971_0 PEGA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009144 434.0
HFD2_k127_4953971_1 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 346.0
HFD2_k127_4953971_2 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000000000000000000000000000381 151.0
HFD2_k127_4958220_0 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 396.0
HFD2_k127_4958220_1 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000002215 241.0
HFD2_k127_4958220_2 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000009128 199.0
HFD2_k127_4959563_1 long-chain fatty acid transporting porin activity K07267 - - 0.000000000000000009299 96.0
HFD2_k127_4959563_2 Forkhead associated domain - - - 0.00000000004473 75.0
HFD2_k127_4959563_3 WD40-like Beta Propeller Repeat - - - 0.000000005474 68.0
HFD2_k127_4962338_0 - - - - 0.00000000000000007555 92.0
HFD2_k127_4962338_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000003617 65.0
HFD2_k127_4969477_0 Phosphate ABC transporter substrate-binding protein K02040 - - 0.000000000000000000000000000000000000000000000006699 185.0
HFD2_k127_4969477_1 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000000006195 132.0
HFD2_k127_4969477_2 Zinc-dependent metalloprotease - - - 0.00000000000002379 76.0
HFD2_k127_4969477_3 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K01179 - 3.2.1.4 0.000376 53.0
HFD2_k127_4970549_0 PFAM Rieske 2Fe-2S domain protein K00479,K00499,K05708 - 1.14.12.19,1.14.15.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 387.0
HFD2_k127_4972695_0 Long-chain fatty acid transport protein K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 303.0
HFD2_k127_497401_0 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000003141 255.0
HFD2_k127_497401_2 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.00000001116 60.0
HFD2_k127_4974204_0 PAS fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 311.0
HFD2_k127_4974204_1 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000001482 202.0
HFD2_k127_4974204_2 - - - - 0.00000000000000000102 96.0
HFD2_k127_4974204_3 Domain of unknown function (DUF4215) - - - 0.000005983 58.0
HFD2_k127_4976297_0 Alpha-2-Macroglobulin K06894 - - 2.114e-195 640.0
HFD2_k127_497662_0 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003633 617.0
HFD2_k127_497662_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001122 249.0
HFD2_k127_4980748_0 PFAM Carbamoyltransferase K00612 - - 6.712e-217 687.0
HFD2_k127_4980748_1 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000000000000000000001318 211.0
HFD2_k127_4988649_0 Thioredoxin - - - 8.007e-234 741.0
HFD2_k127_4988649_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006768 297.0
HFD2_k127_4988649_2 prephenate dehydrogenase K04517,K14187 - 1.3.1.12,5.4.99.5 0.00000000000000000000000000000000000000000000000000000003561 208.0
HFD2_k127_4988649_3 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000002202 66.0
HFD2_k127_4988801_0 Fungalysin metallopeptidase (M36) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009982 507.0
HFD2_k127_4988801_1 Belongs to the phosphoglycerate mutase family - - - 0.0000000000000000000000000000000000000109 154.0
HFD2_k127_4990531_0 Large family of predicted nucleotide-binding domains K07175 - - 1.397e-195 621.0
HFD2_k127_4990531_1 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000186 181.0
HFD2_k127_4990531_2 Beta-L-arabinofuranosidase, GH127 - - - 0.00000001284 63.0
HFD2_k127_4996600_0 AAA ATPase domain - - - 0.0000000000000000000000000000000000000000000000000005728 192.0
HFD2_k127_4996600_1 Insulinase (Peptidase family M16) - - - 0.000000000000000000000000000000000000000000004022 180.0
HFD2_k127_4996600_2 CRS1_YhbY K07574 - - 0.0000000000000000000000000005866 119.0
HFD2_k127_50021_0 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009887 281.0
HFD2_k127_50021_1 MotA/TolQ/ExbB proton channel family K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000003971 240.0
HFD2_k127_50021_2 Biopolymer transport protein ExbD/TolR K03559 - - 0.00000000000000000000000000000000000000000000001918 174.0
HFD2_k127_50021_3 Gram-negative bacterial TonB protein C-terminal - - - 0.0000000000000000000000000000769 126.0
HFD2_k127_5017340_0 MMPL family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005469 544.0
HFD2_k127_502328_0 WGR domain protein - - - 0.00000000000000000000000000000000000000000000000000000007846 207.0
HFD2_k127_502328_1 Beta-L-arabinofuranosidase, GH127 - - - 0.0000000000000000000000000000000000000000000009591 181.0
HFD2_k127_5031937_0 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000005638 271.0
HFD2_k127_5031937_1 Protein serine threonine phosphatase K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000115 262.0
HFD2_k127_5031937_2 serine-type endopeptidase activity K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000003709 228.0
HFD2_k127_5031937_3 Protein serine threonine phosphatase K01090,K20074 - 3.1.3.16 0.00000000000000001801 83.0
HFD2_k127_5038997_0 vancomycin resistance protein K18346 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 491.0
HFD2_k127_5038997_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 427.0
HFD2_k127_5038997_2 Glutathione-dependent formaldehyde-activating - - - 0.00000000000000000000000000000000000000000000000000000000000000000008448 233.0
HFD2_k127_5038997_3 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000001575 141.0
HFD2_k127_5038997_5 TM2 domain - - - 0.0000000000000006084 91.0
HFD2_k127_5041850_0 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000314 229.0
HFD2_k127_5041850_1 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000001444 99.0
HFD2_k127_5045957_0 palmitoyl-(protein) hydrolase activity - - - 0.00000000000000000000000000000000000000000000009006 182.0
HFD2_k127_5045957_1 Si dkey-21a6.5 - - - 0.00000000004145 74.0
HFD2_k127_5046557_0 Pyoverdine/dityrosine biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002416 290.0
HFD2_k127_5046557_1 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.000000000000000000000001146 113.0
HFD2_k127_5049982_1 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000008719 218.0
HFD2_k127_5049982_2 protein conserved in cyanobacteria - - - 0.0000000000000000000000000003161 119.0
HFD2_k127_5049982_3 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000004814 85.0
HFD2_k127_5056384_0 PFAM Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005172 442.0
HFD2_k127_5056384_1 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA - - - 0.0000000000000000000000000000000000000641 147.0
HFD2_k127_5056384_2 Protein of unknown function (DUF4242) - - - 0.00000000000000000000000000000001531 134.0
HFD2_k127_5056485_0 Cyclic nucleotide-monophosphate binding domain K04739 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004659 449.0
HFD2_k127_5056485_1 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000863 380.0
HFD2_k127_5056485_2 Extensin-like protein C-terminus - - - 0.00000000000000000001582 102.0
HFD2_k127_5056485_3 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.0000000000005587 76.0
HFD2_k127_5058610_0 Family membership K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000005515 261.0
HFD2_k127_5058610_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000004065 203.0
HFD2_k127_5058610_2 amine dehydrogenase activity - - - 0.000000000000000000000000003155 124.0
HFD2_k127_5060293_0 HEAT repeats - - - 0.0000000000000000000000000000000000000000008545 179.0
HFD2_k127_5065140_0 Beta propeller domain - - - 0.0000000000000000000000000000000000000000000003981 178.0
HFD2_k127_5066571_0 DNA ligase OB-like domain K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000001423 262.0
HFD2_k127_5066571_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00004848 55.0
HFD2_k127_5068274_0 Putative esterase K07214 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005494 426.0
HFD2_k127_5068274_1 ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007299 400.0
HFD2_k127_5069648_0 Flagellar hook protein FlgE K02390 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000368 394.0
HFD2_k127_5069648_1 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.00000000000000005296 87.0
HFD2_k127_5069648_2 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.0000009203 57.0
HFD2_k127_507723_0 Regulator of chromosome condensation (RCC1) repeat - - - 0.00000000000000000000000000004652 119.0
HFD2_k127_507723_1 structural constituent of cell wall - - - 0.000001471 59.0
HFD2_k127_5080293_0 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005771 287.0
HFD2_k127_5080293_1 PilZ domain - - - 0.00000000000000000000000000000000000000000254 177.0
HFD2_k127_5081387_0 type IV pilus secretin PilQ K02666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009248 485.0
HFD2_k127_5081387_1 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000009695 250.0
HFD2_k127_5081387_2 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000005548 140.0
HFD2_k127_5081520_0 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 5.095e-205 644.0
HFD2_k127_5081520_1 Family membership K08884 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006516 302.0
HFD2_k127_5081520_2 Sigma-54 interaction domain K07714,K07715 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001951 278.0
HFD2_k127_5084375_0 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 2.857e-214 674.0
HFD2_k127_5088734_0 Acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003454 383.0
HFD2_k127_5088734_1 thiolester hydrolase activity - - - 0.00000000000000000000000000000000000000000000001577 176.0
HFD2_k127_5095277_0 Deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000003093 237.0
HFD2_k127_5095277_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001508 228.0
HFD2_k127_5095277_2 EVE domain - - - 0.00000000000000000000000000000000000000005323 158.0
HFD2_k127_5095277_3 DNA-binding regulatory protein K03088 - - 0.00000000000000001548 86.0
HFD2_k127_5095447_0 Aminotransferase K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 591.0
HFD2_k127_5095447_1 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 377.0
HFD2_k127_5095447_2 Oxidoreductase family, C-terminal alpha/beta domain K00010 - 1.1.1.18,1.1.1.369 0.00000000004023 73.0
HFD2_k127_5100330_0 Family membership - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 646.0
HFD2_k127_5100330_1 Protein of unknown function (DUF4242) - - - 0.00000000000000000000002358 106.0
HFD2_k127_5100330_3 Sigma-70 region 2 K03088 - - 0.00002439 54.0
HFD2_k127_5101320_0 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 328.0
HFD2_k127_5101320_1 PFAM Quinohemoprotein amine dehydrogenase A alpha subunit haem binding K08685 - 1.4.9.1 0.0001352 52.0
HFD2_k127_5101978_0 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.000000000000000000000000000000000000000000000000000000000000000001349 235.0
HFD2_k127_5103288_0 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 367.0
HFD2_k127_5103288_1 Family membership K12132 - 2.7.11.1 0.0000000000000000000000003532 109.0
HFD2_k127_5103896_0 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003938 312.0
HFD2_k127_5103896_1 - - - - 0.000000000000009413 79.0
HFD2_k127_5103896_2 Acetyltransferase (GNAT) domain - - - 0.0000000000003568 70.0
HFD2_k127_5106544_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000981 390.0
HFD2_k127_5106544_1 Phosphomannose isomerase type I K01809,K01840 - 5.3.1.8,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 388.0
HFD2_k127_5110757_0 ATP:ADP antiporter activity K03301 - - 0.0000000000000000000000000000000000003005 161.0
HFD2_k127_5110757_1 COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain - - - 0.000000000000001567 79.0
HFD2_k127_5110757_2 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000365 82.0
HFD2_k127_5113228_0 ATP dependent DNA ligase domain protein K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000006929 259.0
HFD2_k127_5113228_1 Astacin (Peptidase family M12A) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001299 254.0
HFD2_k127_5113228_2 exo-alpha-(2->6)-sialidase activity K01186 GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509 3.2.1.18 0.00000000000000000000000000000000000000000000000000000000003923 222.0
HFD2_k127_5116409_0 Proposed nucleic acid binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005161 291.0
HFD2_k127_5116409_1 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000007679 230.0
HFD2_k127_5120760_0 Ham1 family - - - 0.0000000000000000000000000000000000000000003506 167.0
HFD2_k127_5120760_1 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000008116 152.0
HFD2_k127_5120760_2 regulation of response to stimulus - - - 0.00000002158 64.0
HFD2_k127_5132466_0 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004604 259.0
HFD2_k127_5132466_1 COG0188 Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) A subunit K02469 - 5.99.1.3 0.00000000000003936 75.0
HFD2_k127_5132466_2 Pkd domain containing protein - - - 0.0000003555 62.0
HFD2_k127_5137446_0 ABC-type multidrug transport system ATPase component K21397 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005922 443.0
HFD2_k127_5145336_0 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.00000000000000000000000000000000004158 143.0
HFD2_k127_5145336_1 Multicopper K04753 - - 0.0000000000000000004558 94.0
HFD2_k127_5145336_3 - - - - 0.0001447 52.0
HFD2_k127_5154310_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000003189 222.0
HFD2_k127_5154310_1 TIGRFAM outer membrane autotransporter barrel domain protein - - - 0.00000003459 67.0
HFD2_k127_5164362_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000004288 235.0
HFD2_k127_5164362_1 Diacylglycerol acyltransferase - - - 0.000000000000000000000000000000000000000000000000004663 198.0
HFD2_k127_5164362_2 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000001782 149.0
HFD2_k127_5169005_0 Regulator of chromosome condensation (RCC1) repeat - - - 0.00000000000000000000000000000000000000000000000000000001664 209.0
HFD2_k127_5186045_0 - - - - 0.0000000000000000000000000000000000009432 144.0
HFD2_k127_5188347_0 Bacterial PH domain - - - 0.00000000000000000000000000002969 122.0
HFD2_k127_5188762_0 Chagasin family peptidase inhibitor I42 K14475 - - 0.00000000442 66.0
HFD2_k127_5188762_1 amine dehydrogenase activity - - - 0.0004291 52.0
HFD2_k127_5189603_0 GDSL-like Lipase/Acylhydrolase - - - 0.00000000000000000000000000000000000000000000000000402 199.0
HFD2_k127_5189603_1 -O-antigen K02847 - - 0.00000000000000001674 96.0
HFD2_k127_5191870_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002786 273.0
HFD2_k127_5191870_1 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K15520 - 2.3.1.189 0.00000000000000000000000000000000000001191 153.0
HFD2_k127_5191870_2 serine-type endopeptidase activity - - - 0.00000005499 63.0
HFD2_k127_5194588_0 Belongs to the flagella basal body rod proteins family K02392 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002488 269.0
HFD2_k127_5194588_1 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.00005983 53.0
HFD2_k127_5203567_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 323.0
HFD2_k127_5203567_1 Putative restriction endonuclease - - - 0.0000000000000000000000000000000000000000002989 164.0
HFD2_k127_5203567_3 PFAM SNARE associated Golgi protein K03975 - - 0.000000000000000000004157 95.0
HFD2_k127_5204634_0 Bacterial dnaA protein - - - 0.0000000000000000000000000000009303 125.0
HFD2_k127_5205608_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 422.0
HFD2_k127_5205608_1 - - - - 0.00001476 52.0
HFD2_k127_5212105_0 COG0767 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003624 269.0
HFD2_k127_5212105_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000004812 171.0
HFD2_k127_5214392_0 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000002061 171.0
HFD2_k127_5217858_0 response regulator K07713 - - 1.476e-213 673.0
HFD2_k127_5217858_1 cheY-homologous receiver domain - - - 0.0000000000000000001225 95.0
HFD2_k127_5217860_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.914e-278 872.0
HFD2_k127_5217860_1 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000007777 207.0
HFD2_k127_5218896_0 Rhodanese Homology Domain - - - 0.00000000002648 70.0
HFD2_k127_5219467_0 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000001371 185.0
HFD2_k127_5219467_1 - - - - 0.000000000000000000000000000006989 121.0
HFD2_k127_5219467_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000002598 109.0
HFD2_k127_5219467_3 DNA-binding regulatory protein K03088 - - 0.0000000000000000004091 100.0
HFD2_k127_5219467_4 Forkhead associated domain - - - 0.0000168 47.0
HFD2_k127_5226461_0 - - - - 0.00000000000000000000000000000001576 141.0
HFD2_k127_5226461_2 - - - - 0.0000000000000000004607 91.0
HFD2_k127_5230397_0 Lysin motif K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 529.0
HFD2_k127_5230397_1 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.0000000000000000000000245 107.0
HFD2_k127_5240898_0 glycoside hydrolase, family K07273 - - 0.00000000000000000000000000000000000000000014 170.0
HFD2_k127_5256717_0 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179 - 3.2.1.4 0.0000000000000000000000000000000000000000000000001503 188.0
HFD2_k127_5256717_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000008354 192.0
HFD2_k127_5256717_3 Protein of unknown function DUF72 - - - 0.00001929 46.0
HFD2_k127_52617_0 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004504 297.0
HFD2_k127_52617_1 relative of glutathione S-transferase, MAPEG superfamily K07136 - - 0.000000000000000000005957 97.0
HFD2_k127_5265415_0 cellulose binding - - - 0.0000000000000000000009765 102.0
HFD2_k127_5265415_1 FG-GAP repeat - - - 0.000002601 59.0
HFD2_k127_5268699_0 Family membership K08884 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008803 284.0
HFD2_k127_5268699_1 Family membership K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000001283 189.0
HFD2_k127_5268699_3 - - - - 0.000000000000000000007135 101.0
HFD2_k127_5270289_0 Domain of unknown function (DUF4132) - - - 0.0000000000000000000000000000000000000000000000000000000000001489 235.0
HFD2_k127_5272863_0 Predicted metal-dependent hydrolase K07044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007626 273.0
HFD2_k127_5272863_1 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000751 270.0
HFD2_k127_5272863_2 PhoQ Sensor - - - 0.0000000000000000000000000004815 123.0
HFD2_k127_5277688_2 HYR domain - - - 0.0000000004805 72.0
HFD2_k127_5277688_3 - - - - 0.0004938 53.0
HFD2_k127_5278050_0 pyruvate phosphate dikinase K01006 - 2.7.9.1 2.773e-194 620.0
HFD2_k127_5284812_0 magnesium chelatase K03924 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000003216 262.0
HFD2_k127_5284812_1 Uncharacterized conserved protein (DUF2267) - - - 0.000000000000000000000000000000009063 139.0
HFD2_k127_5284812_2 - - - - 0.00000000000000000000000000004981 121.0
HFD2_k127_5284812_3 Protein of unknown function DUF58 - - - 0.00000000000001021 88.0
HFD2_k127_5284812_4 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000005761 66.0
HFD2_k127_5284812_5 Transporter component K07112 - - 0.000006962 53.0
HFD2_k127_5286369_0 Belongs to the glycosyltransferase 26 family K05946 - 2.4.1.187 0.000000000000000000000000000000000000000000000000000000000000000000000000000415 267.0
HFD2_k127_5286369_1 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000002117 243.0
HFD2_k127_5286369_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000001017 233.0
HFD2_k127_5287937_0 Uncharacterized protein conserved in bacteria (DUF2330) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006779 272.0
HFD2_k127_5287937_1 PFAM Endonuclease exonuclease phosphatase - - - 0.000000000000000000000000002648 121.0
HFD2_k127_5287937_2 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.0000004324 62.0
HFD2_k127_5288438_0 UPF0313 protein - - - 3.932e-308 955.0
HFD2_k127_5288438_1 DNA-binding transcription factor activity - - - 0.000000000000000001214 89.0
HFD2_k127_5288924_0 OmpA family K02557 - - 0.000000000000000000000000000000000000000000000000000005549 207.0
HFD2_k127_5288924_2 UPF0391 membrane protein - - - 0.000000000003382 69.0
HFD2_k127_5288924_3 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.000000007271 63.0
HFD2_k127_5289837_0 AAA C-terminal domain K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009562 318.0
HFD2_k127_5289837_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000005592 73.0
HFD2_k127_5289837_2 Helix-turn-helix XRE-family like proteins - - - 0.00002396 52.0
HFD2_k127_5297315_0 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002991 271.0
HFD2_k127_5297315_1 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000003626 223.0
HFD2_k127_5297315_2 Cupin domain - - - 0.000000000000000000000000000005284 124.0
HFD2_k127_5297315_3 WGR domain protein - - - 0.0001185 53.0
HFD2_k127_5297541_0 oxidoreductase activity K07114 - - 3.93e-238 787.0
HFD2_k127_5297541_1 oxidoreductase activity K07114 - - 0.000000000000000000000000000000000000000000000000006516 188.0
HFD2_k127_5299568_0 Flagellar Motor Protein K11892 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002673 507.0
HFD2_k127_5299568_1 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 310.0
HFD2_k127_5299607_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 487.0
HFD2_k127_5299607_1 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000001681 186.0
HFD2_k127_5299607_2 Diguanylate cyclase - - - 0.000000006356 57.0
HFD2_k127_5305439_0 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004484 370.0
HFD2_k127_5305439_1 Putative zinc- or iron-chelating domain K06940 - - 0.00000000001059 70.0
HFD2_k127_5305439_2 hydrolase - - - 0.000001626 59.0
HFD2_k127_5306713_0 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003977 241.0
HFD2_k127_5306713_2 PFAM DGPFAETKE family protein - - - 0.00000000000000000000000000008526 120.0
HFD2_k127_5306713_3 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000004362 107.0
HFD2_k127_5308321_0 Vault protein inter-alpha-trypsin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004906 465.0
HFD2_k127_5316966_0 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000001276 214.0
HFD2_k127_5316966_1 AAA ATPase domain - - - 0.0000000000000000000000000000006903 140.0
HFD2_k127_5317021_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 574.0
HFD2_k127_5317021_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000347 557.0
HFD2_k127_5317021_2 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000321 111.0
HFD2_k127_5317863_0 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000006883 141.0
HFD2_k127_5318386_0 Protein-arginine deiminase (PAD) middle domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 544.0
HFD2_k127_5318386_1 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.0000000000000000000000000000000707 131.0
HFD2_k127_532117_0 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000001664 239.0
HFD2_k127_532117_1 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000007891 124.0
HFD2_k127_5323421_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 342.0
HFD2_k127_5323421_1 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000002212 286.0
HFD2_k127_5323421_2 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 0.00000000000000000000000000000000000000002849 161.0
HFD2_k127_5323421_3 - - - - 0.00000000000004164 79.0
HFD2_k127_5323421_4 - - - - 0.000000000003416 68.0
HFD2_k127_5324040_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 497.0
HFD2_k127_5324040_1 Belongs to the bacterial histone-like protein family K05788 - - 0.00000000000000000000000000000000000001199 145.0
HFD2_k127_5334042_0 Family membership K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008247 285.0
HFD2_k127_5334042_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000003213 233.0
HFD2_k127_5334042_2 HAD-hyrolase-like K01091 - 3.1.3.18 0.000000000000000000000000000000003359 139.0
HFD2_k127_5334064_0 alpha beta - - - 0.00000000000000000000000000000000002513 148.0
HFD2_k127_5334064_1 Protein kinase domain K08884,K12132 - 2.7.11.1 0.00000000000000000007057 99.0
HFD2_k127_5334257_0 protein kinase activity K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000001827 276.0
HFD2_k127_5334257_1 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000001048 233.0
HFD2_k127_5334257_2 cell envelope organization K05807,K08309 - - 0.000000000001485 72.0
HFD2_k127_5351598_0 benzoyl-CoA oxygenase K15512 - 1.14.13.208 4.6e-247 768.0
HFD2_k127_5351598_1 Enoyl-CoA hydratase/isomerase K15513 - 4.1.2.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004729 283.0
HFD2_k127_5360151_0 Endonuclease Exonuclease Phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001622 259.0
HFD2_k127_5360151_1 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000000000000000000000000000000000000000002234 197.0
HFD2_k127_5360151_2 Response regulator receiver domain - - - 0.0000000000000000000000005996 121.0
HFD2_k127_5360185_0 lyase activity - - - 4.587e-219 704.0
HFD2_k127_5360185_1 Putative restriction endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000002304 219.0
HFD2_k127_537464_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K02337,K14162 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.0 1059.0
HFD2_k127_5375330_0 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000002126 193.0
HFD2_k127_5375330_1 Calcium ion binding - GO:0002009,GO:0002165,GO:0003674,GO:0005198,GO:0005201,GO:0005575,GO:0005576,GO:0007275,GO:0007424,GO:0007444,GO:0007472,GO:0007475,GO:0007476,GO:0007552,GO:0007560,GO:0007591,GO:0008150,GO:0008362,GO:0008587,GO:0009653,GO:0009791,GO:0009886,GO:0009887,GO:0009888,GO:0022404,GO:0031012,GO:0032501,GO:0032502,GO:0035107,GO:0035114,GO:0035120,GO:0035220,GO:0035239,GO:0035295,GO:0040003,GO:0040005,GO:0042303,GO:0042335,GO:0044421,GO:0044719,GO:0048513,GO:0048563,GO:0048569,GO:0048707,GO:0048729,GO:0048731,GO:0048736,GO:0048737,GO:0048856,GO:0060429,GO:0060541,GO:0060562,GO:0065007,GO:0065008,GO:0090066 - 0.0009175 51.0
HFD2_k127_5375686_0 AI-2E family transporter - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.000000000000000002571 98.0
HFD2_k127_5375686_1 Trypsin-like serine protease - - - 0.0000000001211 74.0
HFD2_k127_5382779_0 NLP P60 protein - - - 0.000000000000000004863 97.0
HFD2_k127_5382779_1 Involved in the tonB-independent uptake of proteins K03641 - - 0.0000000000007796 80.0
HFD2_k127_5389298_0 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000000007595 183.0
HFD2_k127_5389298_1 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.0000000000000009905 84.0
HFD2_k127_5389298_2 Methyltransferase FkbM domain - - - 0.0000002029 63.0
HFD2_k127_5389298_3 Esterase PHB depolymerase K03932 - - 0.0000029 55.0
HFD2_k127_5398095_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 1.847e-232 741.0
HFD2_k127_5399474_0 PFAM FecR protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000541 289.0
HFD2_k127_5399474_1 CarboxypepD_reg-like domain - - - 0.000000000000000000000000000000000000000000009418 176.0
HFD2_k127_5400221_0 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000633 407.0
HFD2_k127_5400221_3 ATPase activity K01990 - - 0.0000000000000000000000004736 117.0
HFD2_k127_5400221_4 PFAM Stage II sporulation E family protein K01079,K07315 - 3.1.3.3 0.0000000003117 68.0
HFD2_k127_5410266_0 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000289 242.0
HFD2_k127_5412930_0 Beta propeller domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000308 457.0
HFD2_k127_5412930_1 Protein of unknown function (DUF1579) - - - 0.00000000000000000000000000000001578 133.0
HFD2_k127_5415431_0 4Fe-4S single cluster domain of Ferredoxin I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 298.0
HFD2_k127_5415431_1 protein secretion - - - 0.000000000000000000000000004366 122.0
HFD2_k127_5416146_0 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 556.0
HFD2_k127_5416146_1 Phenazine biosynthesis protein PhzF - - - 0.0000000114 57.0
HFD2_k127_5416146_2 protein kinase activity - - - 0.000001036 51.0
HFD2_k127_5420333_0 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003883 488.0
HFD2_k127_5420333_1 Belongs to the MtfA family K09933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004662 250.0
HFD2_k127_5420333_2 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000002973 147.0
HFD2_k127_5420333_3 YCII-related domain - - - 0.00000000000000005312 83.0
HFD2_k127_5420410_0 Lysylphosphatidylglycerol synthase TM region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008327 325.0
HFD2_k127_5420410_1 ATPase associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001321 282.0
HFD2_k127_5420410_2 ATPase associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000009363 175.0
HFD2_k127_5420410_3 MOSC N-terminal beta barrel domain K07140 - - 0.000000000000000000001409 98.0
HFD2_k127_5420518_0 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000001139 239.0
HFD2_k127_5420518_1 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000007475 148.0
HFD2_k127_5421819_0 Tetratricopeptide repeat - - - 0.000000000000000000000000002285 125.0
HFD2_k127_542436_0 Catalyzes the hydrolytic cleavage of a subset of L- isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation K01305 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008270,GO:0008798,GO:0016787,GO:0019538,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 381.0
HFD2_k127_542436_1 Peptidase family S51 K13282 - 3.4.15.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 334.0
HFD2_k127_542436_2 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K03594 - 1.16.3.1 0.0000000000000000001055 100.0
HFD2_k127_5424689_0 chromosome segregation K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 344.0
HFD2_k127_5424689_1 - - - - 0.0000007324 60.0
HFD2_k127_5425589_0 Conserved repeat domain - - - 0.00000000000000000000000000000000000000009195 168.0
HFD2_k127_5425589_1 Chlorophyllase enzyme - - - 0.000001542 60.0
HFD2_k127_5434585_0 Type II IV secretion system protein K02283,K03609 - - 0.000000000000000000002688 104.0
HFD2_k127_5434585_1 Phosphotransferase enzyme family - - - 0.000000000005745 76.0
HFD2_k127_5436508_0 Methyl-accepting chemotaxis protein K03406 - - 7.734e-194 629.0
HFD2_k127_5436508_1 PBS lyase HEAT-like repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009423 495.0
HFD2_k127_5440900_0 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000008674 238.0
HFD2_k127_5440900_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0008152,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0016491,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0055114,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.0007662 50.0
HFD2_k127_5447583_0 Belongs to the peptidase S8 family - - - 0.0 1157.0
HFD2_k127_5447583_1 Cro/C1-type HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005215 347.0
HFD2_k127_5447583_2 Redoxin - - - 0.0000000000000000000000003136 106.0
HFD2_k127_5448002_0 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000000000000000000000000000007146 164.0
HFD2_k127_5448002_1 ligase activity K18660 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015645,GO:0016020,GO:0016053,GO:0016054,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0031957,GO:0031974,GO:0032787,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035336,GO:0035337,GO:0035338,GO:0035383,GO:0035384,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046394,GO:0046395,GO:0046483,GO:0046949,GO:0051186,GO:0051188,GO:0055086,GO:0070013,GO:0071616,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0090407,GO:0090409,GO:0090410,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901568,GO:1901570,GO:1901575,GO:1901576 - 0.0000001945 58.0
HFD2_k127_5448598_0 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000701 213.0
HFD2_k127_5448598_1 adenylate kinase activity K00939 - 2.7.4.3 0.0000000000000000000000000000707 125.0
HFD2_k127_5448598_2 - - - - 0.0000000000000000000000000002147 132.0
HFD2_k127_5457889_0 NADPH:quinone reductase activity K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006112 365.0
HFD2_k127_5457889_1 Elongator protein 3, MiaB family, Radical SAM K06937 - - 0.000000000000000000000000000000000000001806 152.0
HFD2_k127_5457889_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K09251 - 2.6.1.82 0.000000000000000002383 88.0
HFD2_k127_545817_0 epimerase dehydratase K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006986 285.0
HFD2_k127_545817_2 Domain of unknown function (DUF5122) beta-propeller - - - 0.000000000000000000000003169 117.0
HFD2_k127_5460072_0 Phenylacetate-CoA oxygenase - - - 0.00000000000000000000000003724 119.0
HFD2_k127_5460171_0 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000001987 215.0
HFD2_k127_5460171_1 - K12056 - - 0.0000000000000004976 89.0
HFD2_k127_546056_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 344.0
HFD2_k127_5463891_0 ABC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 356.0
HFD2_k127_5463891_1 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001369 277.0
HFD2_k127_5463891_2 Type II secretion system (T2SS), protein F K02653 - - 0.00000000000002827 73.0
HFD2_k127_546559_0 ABC transporter permease K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 316.0
HFD2_k127_546559_1 - - - - 0.000000000000000000000000000000000000000000001062 173.0
HFD2_k127_546559_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.000000000000000000000000000000000000486 143.0
HFD2_k127_546559_3 FtsX-like permease family - - - 0.00000000001019 73.0
HFD2_k127_5469743_0 - - - - 0.000000000000000000000000000000000000003349 163.0
HFD2_k127_5469743_1 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000006135 101.0
HFD2_k127_547572_0 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007134 330.0
HFD2_k127_547572_1 Sigma-54 dependent transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001561 266.0
HFD2_k127_547572_2 Glutamine amidotransferases class-II - - - 0.0000000000000000000000000000000000000000000000007205 181.0
HFD2_k127_547572_3 small periplasmic lipoprotein - - - 0.00000000000000000004039 98.0
HFD2_k127_5481601_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II K01835,K01840 - 5.4.2.2,5.4.2.8 1.086e-210 670.0
HFD2_k127_5481601_1 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 348.0
HFD2_k127_5481601_2 Serine Threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001567 291.0
HFD2_k127_5481601_3 COG COG2755 Lysophospholipase L1 and related esterases - - - 0.00000000001659 71.0
HFD2_k127_5485295_0 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 320.0
HFD2_k127_5485295_1 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.000000006175 67.0
HFD2_k127_5494182_0 protein conserved in bacteria K09930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007728 372.0
HFD2_k127_5494182_1 Putative DNA-binding domain - - - 0.0000000000000000000000000000000000000000000005853 185.0
HFD2_k127_5494182_2 energy transducer activity - - - 0.0000000003059 65.0
HFD2_k127_5500410_0 amine dehydrogenase activity K12132 - 2.7.11.1 0.000000003285 68.0
HFD2_k127_5507926_0 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000005349 243.0
HFD2_k127_5507926_1 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000002145 251.0
HFD2_k127_5507926_2 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000000001323 192.0
HFD2_k127_5507926_3 SURF4 family K15977 - - 0.0000000000000000000000000000000000158 141.0
HFD2_k127_5507926_4 - - - - 0.000001976 58.0
HFD2_k127_5509358_0 Site-specific DNA-methyltransferase (Adenine-specific) K06223 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 303.0
HFD2_k127_5509358_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000357 121.0
HFD2_k127_5510420_0 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007476 305.0
HFD2_k127_5510420_1 Protein conserved in bacteria K09939 - - 0.000000000000000000000000000000000000000000000000000000000000000002738 235.0
HFD2_k127_5510420_2 Putative RNA methylase family UPF0020 - - - 0.000000000000000000001373 108.0
HFD2_k127_5511952_0 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000002768 131.0
HFD2_k127_5511952_1 Protein conserved in bacteria - - - 0.000000000000006484 77.0
HFD2_k127_5511952_2 DNA-templated transcription, initiation - - - 0.00000000000006718 83.0
HFD2_k127_5511952_4 FHA domain - - - 0.000000001268 64.0
HFD2_k127_5511952_5 Protein conserved in bacteria - - - 0.0000001552 59.0
HFD2_k127_5513392_0 COG COG0210 Superfamily I DNA and RNA helicases DNA replication recombination and repair K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 441.0
HFD2_k127_551810_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002802 353.0
HFD2_k127_551810_1 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007441 344.0
HFD2_k127_551810_2 Belongs to the peptidase S8 family K12287 - - 0.000000000000000000000004035 113.0
HFD2_k127_5520968_0 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 294.0
HFD2_k127_5520968_1 Splits dipeptides with a prolyl residue in the C- terminal position K01271 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009056,GO:0009987,GO:0016787,GO:0016805,GO:0019538,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0070573,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004681 296.0
HFD2_k127_5520968_2 acyl-coa-binding protein - - - 0.0000000000000000000000003532 109.0
HFD2_k127_5523069_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 1.517e-206 657.0
HFD2_k127_5523069_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 354.0
HFD2_k127_5523069_2 GDSL-like Lipase/Acylhydrolase family - - - 0.000008014 57.0
HFD2_k127_5523770_0 B12 binding domain - - - 4.851e-266 835.0
HFD2_k127_5523770_1 Outer membrane efflux protein K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 299.0
HFD2_k127_5523770_2 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.00000000000000000000000000000000000000000000000000000000000000000001532 247.0
HFD2_k127_5523770_3 Histidine kinase - - - 0.000000000000000000003498 94.0
HFD2_k127_5525588_0 dehydrogenase, E1 component K00164 - 1.2.4.2 1.211e-264 826.0
HFD2_k127_5525588_1 mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 375.0
HFD2_k127_5527515_0 Diadenosine tetraphosphatase and related serine threonine protein phosphatases K07313 - 3.1.3.16 0.00000000000000000000000000000000000000000000000002322 190.0
HFD2_k127_5527515_1 Phage integrase family - - - 0.0000000000000000000000000000000000000008972 157.0
HFD2_k127_5529133_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 1.028e-285 906.0
HFD2_k127_5529133_1 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 407.0
HFD2_k127_5529133_2 4Fe-4S ferredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006112 361.0
HFD2_k127_5529133_3 Conserved hypothetical protein 698 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005841 287.0
HFD2_k127_5529133_4 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003335 248.0
HFD2_k127_5529133_5 transporter component K07112 - - 0.0000000000000000000000000000000000000006445 153.0
HFD2_k127_5529133_6 Transporter Component K07112 - - 0.00000000000000000000000000000000002321 146.0
HFD2_k127_5529133_7 Methyltransferase domain protein - - - 0.000000000000000000001759 103.0
HFD2_k127_5529133_8 Universal stress protein family - - - 0.00000000000000000007033 95.0
HFD2_k127_5529133_9 Polysulphide reductase, NrfD - - - 0.000000003347 62.0
HFD2_k127_5529953_0 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000001582 166.0
HFD2_k127_5529953_1 - - - - 0.0000000000000000000000000000001434 132.0
HFD2_k127_5533165_0 ErfK ybiS ycfS ynhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006795 473.0
HFD2_k127_5537548_0 Belongs to the TPP enzyme family K00156 - 1.2.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 585.0
HFD2_k127_5537548_1 Sarcosine oxidase K00303 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005632 582.0
HFD2_k127_5537548_2 Inositol monophosphatase family K01082 - 3.1.3.7 0.000000000000000000000000000000000000001894 158.0
HFD2_k127_5537548_3 Aldo Keto reductase - - - 0.0000000000000000000000000000001573 126.0
HFD2_k127_5538701_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000297 147.0
HFD2_k127_5538701_1 VIT family - - - 0.0000000000000000000000009959 113.0
HFD2_k127_5538701_2 Universal stress protein - - - 0.00000000000000000000009111 106.0
HFD2_k127_5547727_0 von Willebrand factor type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005578 326.0
HFD2_k127_5552216_0 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000166 182.0
HFD2_k127_5554496_0 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000001792 242.0
HFD2_k127_5554496_1 D-alanyl-D-alanine carboxypeptidase K17733 - - 0.000000000000000000001309 105.0
HFD2_k127_555667_0 PFAM response regulator receiver K03406 - - 0.000000000000001695 87.0
HFD2_k127_5557550_0 Nucleotidyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 337.0
HFD2_k127_5557550_1 Belongs to the ABC transporter superfamily K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 338.0
HFD2_k127_5557550_2 Calcineurin-like phosphoesterase K03651 - 3.1.4.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006165 286.0
HFD2_k127_5557776_0 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000001063 234.0
HFD2_k127_5557776_1 Serine/Threonine protein kinases, catalytic domain K12132 - 2.7.11.1 0.0000000000001139 76.0
HFD2_k127_5563205_0 PFAM N-acetylneuraminic acid synthase K01654,K18430 - 2.5.1.101,2.5.1.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 381.0
HFD2_k127_5563205_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003712 280.0
HFD2_k127_5563205_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000002386 57.0
HFD2_k127_5568183_0 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000000000000000000000000000000000003416 203.0
HFD2_k127_5568183_1 VWA domain containing CoxE-like protein K07161 - - 0.000000000001807 68.0
HFD2_k127_5570852_1 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001092 266.0
HFD2_k127_5570852_2 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000001379 253.0
HFD2_k127_5570852_3 pseudouridine synthase activity K06178,K06183,K07058 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.22 0.000000000000000000000003094 108.0
HFD2_k127_5571727_0 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000001476 235.0
HFD2_k127_5571727_1 Pfam:HipA_N K07154 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000028 229.0
HFD2_k127_5571727_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000001782 84.0
HFD2_k127_5571727_3 Helix-turn-helix - - - 0.000000000001507 74.0
HFD2_k127_5572016_0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004469 424.0
HFD2_k127_5572016_1 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000006525 239.0
HFD2_k127_5572016_2 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000000000002077 142.0
HFD2_k127_5572016_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000001177 109.0
HFD2_k127_5572016_4 Belongs to the bacterial histone-like protein family - - - 0.00000000000000000000121 98.0
HFD2_k127_5572594_0 Belongs to the UPF0061 (SELO) family - - - 0.000003204 60.0
HFD2_k127_5576260_0 - - - - 0.00000000000002858 81.0
HFD2_k127_5576260_1 PEGA domain - - - 0.0003859 52.0
HFD2_k127_5583420_0 non-canonical purine NTP pyrophosphatase, RdgB HAM1 family K02428 - 3.6.1.66 0.000000000000000000000000000001272 129.0
HFD2_k127_5583420_1 - - - - 0.000000002544 68.0
HFD2_k127_5583420_2 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.00001479 50.0
HFD2_k127_5589584_0 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K14257 - 1.14.19.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008423 389.0
HFD2_k127_5589584_1 Kelch motif - - - 0.0000000000000000000000000000000000000000000000000000000000007582 238.0
HFD2_k127_5589584_2 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000000000000000000000000000000000004399 169.0
HFD2_k127_5589584_3 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000003112 105.0
HFD2_k127_5589584_4 pkhd-type hydroxylase K07336 - - 0.000000001762 58.0
HFD2_k127_5594456_0 Belongs to the ClpA ClpB family K03694 - - 2.463e-305 958.0
HFD2_k127_5594456_1 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000000000000000000000003391 134.0
HFD2_k127_5594869_0 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005115 314.0
HFD2_k127_5594869_2 phosphorelay signal transduction system K01768,K10941,K11894 - 4.6.1.1 0.000008385 50.0
HFD2_k127_5598177_0 Belongs to the allantoicase family K01477 - 3.5.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 490.0
HFD2_k127_5598177_1 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000003978 276.0
HFD2_k127_5598256_0 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005572 392.0
HFD2_k127_5598256_1 Cytochrome c K08685 - 1.4.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004315 361.0
HFD2_k127_5598256_2 Binding-protein-dependent transport system inner membrane component K05815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 342.0
HFD2_k127_5598256_3 Binding-protein-dependent transport system inner membrane component K02025,K05814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 340.0
HFD2_k127_5598256_4 PFAM Permease for cytosine purines, uracil, thiamine, allantoin K03457 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001885 300.0
HFD2_k127_5598256_5 Belongs to the DegT DnrJ EryC1 family K13017 - 2.6.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000611 251.0
HFD2_k127_5598256_6 PFAM Oxidoreductase K18855 - 1.1.1.374 0.000000000000000000000000000000000000000000001733 179.0
HFD2_k127_5598256_7 Glycosyl transferase, family 2 - - - 0.000000000000000001109 95.0
HFD2_k127_5598256_8 transcriptional K05799 - - 0.000000000000005216 85.0
HFD2_k127_5601608_0 Ammonium Transporter Family K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 560.0
HFD2_k127_5601608_1 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000000000000000000000000000000002561 154.0
HFD2_k127_5601608_2 response regulator K07657 - - 0.0000000000000000000000000000000000001085 150.0
HFD2_k127_5601608_3 pyrroloquinoline quinone binding K12287 - - 0.0000000000000000005871 93.0
HFD2_k127_5601608_4 TonB system transport protein ExbB TolQ K03561 - - 0.00000000008634 68.0
HFD2_k127_5601855_0 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000000000000000000000008874 138.0
HFD2_k127_5602501_0 Oxidoreductase K19813 - 1.1.5.9 0.000000005044 58.0
HFD2_k127_5603504_0 radical SAM domain protein - - - 0.0000000000000000000000000000101 129.0
HFD2_k127_5603504_1 - - - - 0.000000003398 66.0
HFD2_k127_5603932_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472 - 1.1.1.336 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009758 311.0
HFD2_k127_5603932_1 Male sterility protein - - - 0.0000000000000000001014 89.0
HFD2_k127_5606391_0 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.0000000007284 70.0
HFD2_k127_5606391_1 PFAM Radical SAM domain protein - - - 0.000003247 57.0
HFD2_k127_5608217_0 phosphate-selective porin O and P - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001967 264.0
HFD2_k127_5614687_0 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000000000000000000000001139 171.0
HFD2_k127_5614687_1 regulation of canonical Wnt signaling pathway involved in osteoblast differentiation K01691,K06252 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0007154,GO:0007165,GO:0007166,GO:0007224,GO:0007275,GO:0007399,GO:0008037,GO:0008038,GO:0008039,GO:0008150,GO:0008589,GO:0009966,GO:0009967,GO:0009987,GO:0010646,GO:0010647,GO:0022008,GO:0023051,GO:0023052,GO:0023056,GO:0030154,GO:0030182,GO:0031012,GO:0031647,GO:0032501,GO:0032502,GO:0044421,GO:0045880,GO:0048468,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0048666,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050821,GO:0050896,GO:0051716,GO:0065007,GO:0065008 - 0.000000001446 66.0
HFD2_k127_5615788_0 - - - - 0.000000000000000000000000000000003901 146.0
HFD2_k127_5615788_1 - - - - 0.000000000000000003056 86.0
HFD2_k127_5617850_0 two component, sigma54 specific, transcriptional regulator, Fis family K07712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 335.0
HFD2_k127_5619107_0 Vault protein inter-alpha-trypsin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 318.0
HFD2_k127_5619107_1 Belongs to the ompA family - - - 0.0000000008704 70.0
HFD2_k127_5621534_0 COG0553 Superfamily II DNA RNA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007772 454.0
HFD2_k127_5621534_1 lipolytic protein G-D-S-L family - - - 0.0000000000000000000005596 103.0
HFD2_k127_5628937_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002928 542.0
HFD2_k127_5628937_1 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 381.0
HFD2_k127_5630911_0 pyrroloquinoline quinone binding - - - 0.000000000002974 79.0
HFD2_k127_5630911_1 amine dehydrogenase activity - - - 0.0009338 49.0
HFD2_k127_5631025_0 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.00000000000000000000000000000000000000000000000000000000001468 210.0
HFD2_k127_5631025_1 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000001583 184.0
HFD2_k127_5631443_0 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000177 273.0
HFD2_k127_5634307_0 - - - - 0.000000000000000000000000000000002741 145.0
HFD2_k127_5634307_1 - K21449 - - 0.0000000000000000005499 91.0
HFD2_k127_5634307_2 response to acidic pH - - - 0.000000000000000483 86.0
HFD2_k127_5636331_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 601.0
HFD2_k127_5636331_1 histidine kinase, HAMP - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 340.0
HFD2_k127_5636331_2 Polysaccharide deacetylase K22278 - 3.5.1.104 0.0000000007165 60.0
HFD2_k127_5636507_1 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000005697 256.0
HFD2_k127_5636507_2 phosphate ion binding - - - 0.00000000000000000000000000000000000000001326 173.0
HFD2_k127_5636507_3 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000001886 160.0
HFD2_k127_5636507_4 - - - - 0.00000000000000000000000000001521 132.0
HFD2_k127_5639985_0 AAA ATPase domain - - - 0.00000000000000000000000000000000000000000000000000002173 214.0
HFD2_k127_5639985_1 ester cyclase - - - 0.000000000000002446 84.0
HFD2_k127_5639985_2 SnoaL-like polyketide cyclase - - - 0.0000000000002052 77.0
HFD2_k127_5641450_0 Fe-S oxidoreductases K22226 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007957 447.0
HFD2_k127_5641450_1 serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005706 328.0
HFD2_k127_5641450_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000418 85.0
HFD2_k127_5642847_0 Fe-S oxidoreductases K22226 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 438.0
HFD2_k127_5642847_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000001112 166.0
HFD2_k127_5644766_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003367 379.0
HFD2_k127_5644766_1 alkaline phosphatase K01113 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 306.0
HFD2_k127_5644766_2 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000003867 157.0
HFD2_k127_5645659_0 Domain of unknown function (DUF4394) - - - 0.00000000000000000001082 99.0
HFD2_k127_5645659_1 Protein tyrosine kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.0000000000009647 81.0
HFD2_k127_5646644_1 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0001553 53.0
HFD2_k127_564886_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000001609 133.0
HFD2_k127_564886_1 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.000000001013 68.0
HFD2_k127_5659341_0 kinase activity K01007 - 2.7.9.2 5.831e-242 776.0
HFD2_k127_5659341_1 pseudouridine synthase activity K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000001053 196.0
HFD2_k127_5659738_0 Histidine triad (Hit) protein K02503 - - 0.000000000000000000000000000000000000000000000004956 181.0
HFD2_k127_5659738_1 Putative glycosyl hydrolase domain - - - 0.000000000000000000000000000000000000497 156.0
HFD2_k127_5660581_0 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000584 362.0
HFD2_k127_5660581_1 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006654 276.0
HFD2_k127_5660581_2 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000000009488 167.0
HFD2_k127_5660581_3 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily K07127 - 3.5.2.17 0.0000000000000000000000000000000000002585 144.0
HFD2_k127_5660581_4 PFAM Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase K16840 - 4.1.1.97 0.00000000001485 65.0
HFD2_k127_5660581_5 Type IV minor pilin ComP, DNA uptake sequence receptor K02650 - - 0.0007587 49.0
HFD2_k127_5667333_0 lysine 2,3-aminomutase K01843 - 5.4.3.2 8.555e-225 706.0
HFD2_k127_5667333_1 Sulfatase K01133 - 3.1.6.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 372.0
HFD2_k127_5669007_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000004764 84.0
HFD2_k127_5669763_0 Zinc-dependent metalloprotease - - - 0.0000000000000000000000000000000000000000000000004545 189.0
HFD2_k127_5670513_0 TIGRFAM repeat-companion domain TIGR02996 - - - 0.000000009897 66.0
HFD2_k127_5675671_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.48e-272 852.0
HFD2_k127_5681081_0 Surface antigen K07277,K07278 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002015 286.0
HFD2_k127_5681081_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000766 254.0
HFD2_k127_5681534_0 Linear gramicidin synthase subunit - - - 8.168e-206 670.0
HFD2_k127_5682877_0 beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 393.0
HFD2_k127_5682877_1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 394.0
HFD2_k127_5682877_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007241 358.0
HFD2_k127_5682877_3 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 347.0
HFD2_k127_5682877_4 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007864 311.0
HFD2_k127_5682877_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 291.0
HFD2_k127_5682877_6 Conserved Protein - GO:0000270,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0030203,GO:0031224,GO:0042546,GO:0043164,GO:0043170,GO:0044085,GO:0044425,GO:0044464,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901564 - 0.000000005765 64.0
HFD2_k127_5682877_7 Spore coat protein CotH - - - 0.0000001935 64.0
HFD2_k127_5682877_8 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000001405 54.0
HFD2_k127_5683304_0 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007961 253.0
HFD2_k127_5683304_1 Peptidyl-prolyl cis-trans K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000001305 156.0
HFD2_k127_5683304_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000002433 144.0
HFD2_k127_5683304_3 PPIC-type PPIASE domain - - - 0.00000000000000000000001464 110.0
HFD2_k127_5684032_0 - - - - 0.0000000000000000000002835 112.0
HFD2_k127_5684032_1 Transcription factor zinc-finger - - - 0.00000004831 64.0
HFD2_k127_5684032_2 protein related to plant photosystem II stability assembly factor - - - 0.0004867 48.0
HFD2_k127_5684993_0 Beta propeller domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 492.0
HFD2_k127_5684993_1 Belongs to the peptidase S8 family K12287 - - 0.0000000000000000000000000000000000000000000000000000000002875 216.0
HFD2_k127_5684993_2 pseudouridine synthase activity K06178,K06183,K07058 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.22 0.00004446 49.0
HFD2_k127_5692863_0 Forkhead associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 338.0
HFD2_k127_5692863_2 - - - - 0.00001538 55.0
HFD2_k127_5700667_0 Protein kinase domain K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 378.0
HFD2_k127_5700667_1 spectrin binding - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006888,GO:0008092,GO:0008093,GO:0008150,GO:0016020,GO:0016192,GO:0030674,GO:0044464,GO:0046907,GO:0048193,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0060090,GO:0071944 - 0.0000000004284 72.0
HFD2_k127_5700667_2 Glutaredoxin K18917 - 1.20.4.3 0.0005045 47.0
HFD2_k127_5702170_0 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003668 308.0
HFD2_k127_5702170_2 Oxygen tolerance - - - 0.0000000000003232 80.0
HFD2_k127_5706303_0 Type III secretion protein K03230 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 522.0
HFD2_k127_5706303_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 423.0
HFD2_k127_5706303_2 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006756 331.0
HFD2_k127_5706303_3 MOSC domain - - - 0.0000000000000000000000000000000000000000004971 166.0
HFD2_k127_5708035_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.00000000000000000000000000000000000000000000000000000000000000005554 225.0
HFD2_k127_5708035_2 TB domain K06825 GO:0003674,GO:0005198,GO:0005201,GO:0005575,GO:0005576,GO:0008150,GO:0009653,GO:0031012,GO:0032502,GO:0044421,GO:0048583,GO:0048856,GO:0050789,GO:0050794,GO:0065007,GO:0090287 - 0.00000002416 63.0
HFD2_k127_5709069_0 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 321.0
HFD2_k127_5713944_0 - K00712 - 2.4.1.52 0.0000000006372 71.0
HFD2_k127_5713944_1 Pectate lyase superfamily protein - - - 0.000001747 61.0
HFD2_k127_5717113_0 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 460.0
HFD2_k127_5717113_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000037 172.0
HFD2_k127_5718828_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003132 274.0
HFD2_k127_5718828_1 GAF domain - - - 0.0000718 50.0
HFD2_k127_5719947_0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007899 314.0
HFD2_k127_5719947_1 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 291.0
HFD2_k127_5721165_0 glyoxalase III activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003616 368.0
HFD2_k127_5721165_1 - - - - 0.0000000000000000000000007973 113.0
HFD2_k127_5721867_0 Predicted nucleotidyltransferase K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009985 531.0
HFD2_k127_5721867_2 Predicted nucleotidyltransferase K07074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003205 279.0
HFD2_k127_5721867_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001143 264.0
HFD2_k127_5721867_4 Amino-transferase class IV K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000002405 179.0
HFD2_k127_5721867_5 Cupin domain - - - 0.0000000000000000000000000000000000001575 144.0
HFD2_k127_5721867_6 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000001489 143.0
HFD2_k127_5721867_7 Uncharacterized conserved protein (DUF2304) K09153 - - 0.0000003711 57.0
HFD2_k127_5722230_0 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 372.0
HFD2_k127_5722230_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000007731 228.0
HFD2_k127_5722230_2 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000008978 113.0
HFD2_k127_5722515_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009604 380.0
HFD2_k127_5722515_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000001921 213.0
HFD2_k127_5725604_0 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000000000000000000000000000009292 216.0
HFD2_k127_5725604_1 Catalase - - - 0.0000000000000000000000000000000000000000000000000002587 198.0
HFD2_k127_5734312_0 helicase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 392.0
HFD2_k127_5738336_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 516.0
HFD2_k127_5738336_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005721 296.0
HFD2_k127_5738336_2 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.000000000000000000000000000000000000000002275 156.0
HFD2_k127_5738336_3 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000000000000000000000000000002136 134.0
HFD2_k127_5739671_0 Rhomboid family K19225 - 3.4.21.105 0.00000000000000000002775 101.0
HFD2_k127_5741207_0 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 390.0
HFD2_k127_5743364_0 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000002994 188.0
HFD2_k127_5743364_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000001621 191.0
HFD2_k127_5743364_2 protein conserved in bacteria K09931 - - 0.00001675 50.0
HFD2_k127_5746121_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 9.975e-232 739.0
HFD2_k127_5751178_0 PHP domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005356 369.0
HFD2_k127_5751178_2 Protein of unknown function DUF58 - - - 0.00000000000000133 91.0
HFD2_k127_5768729_0 Barrel-sandwich domain of CusB or HlyD membrane-fusion K18302 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 294.0
HFD2_k127_5768729_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0000000001514 63.0
HFD2_k127_5768729_2 negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment - - - 0.0000007293 59.0
HFD2_k127_5768729_3 WD40-like Beta Propeller - - - 0.000003188 52.0
HFD2_k127_5781564_0 ATP:ADP antiporter activity K03301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 320.0
HFD2_k127_5782273_0 TonB dependent receptor - - - 2.497e-263 837.0
HFD2_k127_5782273_1 MotA TolQ ExbB proton channel K03561,K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000816 235.0
HFD2_k127_5782273_2 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000000000000000000000000000000000000000000000000000003892 202.0
HFD2_k127_5782273_3 - - - - 0.00000000000000000000000002067 123.0
HFD2_k127_5782273_4 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.00000000000000000008479 100.0
HFD2_k127_5790375_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004238 325.0
HFD2_k127_5790375_1 phosphoglycolate phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001433 258.0
HFD2_k127_5794525_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 499.0
HFD2_k127_5794525_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 441.0
HFD2_k127_5804607_0 Belongs to the aldehyde dehydrogenase family K22445 - 1.2.99.10 0.00000000000000000000000000000000000000000000000000000000007873 213.0
HFD2_k127_5804607_1 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000000000002317 79.0
HFD2_k127_5804607_2 Beta propeller domain - - - 0.00000000002217 74.0
HFD2_k127_5805655_0 Bacterial regulatory protein, Fis family K02584 - - 0.00000000000000000000000000000000000000000000000000000000001401 232.0
HFD2_k127_5805655_1 Cytochrome b subunit of the bc complex K00412 - - 0.0000000000000000000000000000000000000000000000000278 186.0
HFD2_k127_5805655_2 Uncharacterised protein family (UPF0259) - - - 0.0000000000000000000000000008173 123.0
HFD2_k127_5808637_0 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009218 261.0
HFD2_k127_5808637_1 - - - - 0.000000000000003859 80.0
HFD2_k127_581007_0 Protein conserved in bacteria K09859 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 312.0
HFD2_k127_581007_1 Collagen-binding surface adhesin SpaP (antigen I II family) K07337 - - 0.0000000000000000000000000000000000000000000000001186 184.0
HFD2_k127_5810256_0 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 466.0
HFD2_k127_5810256_1 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000158 138.0
HFD2_k127_5810256_2 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000001362 88.0
HFD2_k127_5817368_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 553.0
HFD2_k127_5817368_1 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000055 218.0
HFD2_k127_5824089_1 Lysozyme inhibitor LprI - - - 0.0007277 51.0
HFD2_k127_5825168_0 Iron-containing redox enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001355 271.0
HFD2_k127_5825168_1 - - - - 0.00000000000000000000000000000000000000000000000000000000008648 216.0
HFD2_k127_5825168_2 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000001046 150.0
HFD2_k127_5825168_3 - - - - 0.000000000000000000000000000000003977 135.0
HFD2_k127_5828432_0 Molydopterin dinucleotide binding domain - - - 0.0 1250.0
HFD2_k127_5829023_0 MaoC like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003292 312.0
HFD2_k127_5829023_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000001789 95.0
HFD2_k127_5829023_2 Bacterial export proteins, family 1 K03228 - - 0.0000168 55.0
HFD2_k127_583329_0 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003226 347.0
HFD2_k127_583329_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000001499 192.0
HFD2_k127_583329_2 peptidyl-tyrosine sulfation - - - 0.00000000006648 75.0
HFD2_k127_5838365_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000005494 243.0
HFD2_k127_5839169_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 539.0
HFD2_k127_5839169_1 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 330.0
HFD2_k127_5839283_0 Signal peptide peptidase K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006177 428.0
HFD2_k127_5839283_1 Forkhead associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 315.0
HFD2_k127_5839283_2 Nudix hydrolase K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000001957 209.0
HFD2_k127_5841052_0 Domain of unknown function (DUF4388) K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 415.0
HFD2_k127_5841052_1 Serine threonine protein kinase K12132 - 2.7.11.1 0.000002598 58.0
HFD2_k127_5843518_0 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007114 299.0
HFD2_k127_5843518_1 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001571 272.0
HFD2_k127_5843518_2 protein trimerization - - - 0.00000000000000000000000000000000000009061 157.0
HFD2_k127_5843518_3 - - - - 0.000000000000000000000000000000000004226 148.0
HFD2_k127_5843518_4 Protein kinase domain K08884,K12132 - 2.7.11.1 0.00000000002272 75.0
HFD2_k127_5845567_0 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000005178 143.0
HFD2_k127_5845567_1 Belongs to the ompA family - - - 0.00000000000000000000000000003398 136.0
HFD2_k127_5849590_0 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009148 484.0
HFD2_k127_5849590_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 420.0
HFD2_k127_5849590_2 Cytochrome c K08685 - 1.4.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007907 316.0
HFD2_k127_5849590_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000009738 218.0
HFD2_k127_5854167_0 peptidyl-tyrosine sulfation - - - 0.000000000000000000004459 108.0
HFD2_k127_5854167_1 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000006321 57.0
HFD2_k127_5856129_0 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 301.0
HFD2_k127_5859098_0 OmpA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004749 327.0
HFD2_k127_5859098_1 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000183 265.0
HFD2_k127_5859098_2 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000000000000000000000008513 214.0
HFD2_k127_5859098_3 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.00000000000000000000000000000001636 143.0
HFD2_k127_5859098_4 Leucine-rich repeat (LRR) protein - - - 0.000000000000002057 89.0
HFD2_k127_5859098_5 amine dehydrogenase activity - - - 0.000000000122 72.0
HFD2_k127_5859098_6 Fibronectin type 3 domain - - - 0.00003494 56.0
HFD2_k127_5860053_0 component of anaerobic - - - 0.000000000000000000000000000000000001278 147.0
HFD2_k127_5860053_1 4Fe-4S binding domain - - - 0.000000000000000000000000000000002718 146.0
HFD2_k127_5860053_2 - - - - 0.00000284 54.0
HFD2_k127_5866813_0 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000007715 241.0
HFD2_k127_5866813_3 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.000000005139 57.0
HFD2_k127_5867266_0 MMPL family K07003 - - 2.155e-209 670.0
HFD2_k127_587373_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006085 342.0
HFD2_k127_587373_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000306 72.0
HFD2_k127_5876671_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 337.0
HFD2_k127_5876790_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009331 322.0
HFD2_k127_5876790_1 PFAM regulator of chromosome condensation, RCC1 - - - 0.000000000000000000000000000000002423 149.0
HFD2_k127_5876790_2 SMI1 / KNR4 family - GO:0008150,GO:0032995,GO:0044087,GO:0050789,GO:0050794,GO:0065007,GO:1903338 - 0.0000007066 61.0
HFD2_k127_5879308_0 HAD-superfamily subfamily IB hydrolase, TIGR01490 - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000005244 102.0
HFD2_k127_5879308_1 Pilus assembly protein, PilP K02665 - - 0.00000000000002712 81.0
HFD2_k127_5879308_2 PFAM Leucine Rich Repeat K19613 - - 0.0000001455 63.0
HFD2_k127_5882140_0 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005738 468.0
HFD2_k127_5882140_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 282.0
HFD2_k127_5882140_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007741 244.0
HFD2_k127_5882140_3 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000008542 188.0
HFD2_k127_5885065_0 helix_turn_helix, Lux Regulon - - - 0.0000001742 59.0
HFD2_k127_5885065_1 phosphate ion binding - - - 0.00001795 48.0
HFD2_k127_5885065_2 helix_turn_helix, Lux Regulon - - - 0.00002982 53.0
HFD2_k127_5886632_0 helicase superfamily c-terminal domain K19789 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 362.0
HFD2_k127_5886632_1 FAD dependent oxidoreductase K00301 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 353.0
HFD2_k127_5886632_2 PFAM amidinotransferase K01482 - 3.5.3.18 0.000000000000000000000000000000000000000000000000000000000001559 218.0
HFD2_k127_5890415_0 Low affinity iron permease - - - 0.000000000000000000000000000000000000002564 152.0
HFD2_k127_5890415_1 glyoxalase III activity - - - 0.0000000000000000000000007226 111.0
HFD2_k127_589300_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 312.0
HFD2_k127_589300_1 protein kinase activity K08884 - 2.7.11.1 0.000000000000000000000000000000000000000000000000001476 200.0
HFD2_k127_5893426_0 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 484.0
HFD2_k127_5893426_1 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005818 324.0
HFD2_k127_5893426_2 Papain family cysteine protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000005798 250.0
HFD2_k127_5893426_3 iron ion binding - - - 0.000000000000000000000000000000000004698 143.0
HFD2_k127_5893426_4 - - - - 0.0000000000000005819 88.0
HFD2_k127_5893426_5 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000000214 55.0
HFD2_k127_5895861_0 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 363.0
HFD2_k127_5895861_2 cell septum assembly - - - 0.00000000000000001593 83.0
HFD2_k127_5896458_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005338 515.0
HFD2_k127_5896458_1 - - - - 0.00000000003493 72.0
HFD2_k127_5896458_2 gluconolactonase activity - - - 0.0001025 53.0
HFD2_k127_590040_0 Surface antigen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004949 423.0
HFD2_k127_590040_1 - - - - 0.00000000000000000000000000000000000000000000000000000000001016 214.0
HFD2_k127_590040_2 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000002551 121.0
HFD2_k127_5905359_0 Gram-negative bacterial TonB protein C-terminal - - - 0.000000000000000009479 93.0
HFD2_k127_590924_0 - - - - 0.00000000000000000000000000000000000000001669 158.0
HFD2_k127_590924_1 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000003877 122.0
HFD2_k127_590924_2 COG4635 Flavodoxin K00230 - 1.3.5.3 0.000000000000003392 87.0
HFD2_k127_5918436_0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000004068 245.0
HFD2_k127_5918436_1 Protein of unknown function (DUF1232) - - - 0.0000000000000000000000000000000000000000000000001624 183.0
HFD2_k127_5918436_2 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000005442 186.0
HFD2_k127_5926184_0 PhoD-like phosphatase K01113 - 3.1.3.1 0.0000000000000000004605 97.0
HFD2_k127_5927911_0 Aminotransferase K00813,K00832 GO:0003674,GO:0003824,GO:0004069,GO:0004838,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006531,GO:0006532,GO:0006551,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0008793,GO:0009058,GO:0009066,GO:0009067,GO:0009072,GO:0009073,GO:0009081,GO:0009082,GO:0009094,GO:0009095,GO:0009098,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019292,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0033585,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050048,GO:0050662,GO:0070279,GO:0070547,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 2.6.1.1,2.6.1.57 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009595 423.0
HFD2_k127_5927911_1 SpoU rRNA Methylase family K00556 - 2.1.1.34 0.00000000000000000000000000000000131 132.0
HFD2_k127_5928879_0 AMP-binding enzyme C-terminal domain K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004509 584.0
HFD2_k127_5928879_1 endonuclease activity K07451 - - 0.0000000000000000000000000000000000007056 154.0
HFD2_k127_5932323_0 AMP-binding enzyme K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 595.0
HFD2_k127_5932323_1 Cation transporter/ATPase, N-terminus K01531,K12955 - 3.6.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000003053 267.0
HFD2_k127_5932323_2 Lysylphosphatidylglycerol synthase TM region - - - 0.00000000000000000000000000000000000000000008168 174.0
HFD2_k127_5943049_0 alpha beta - - - 0.000000000000000000000000000000000000000000000000004737 196.0
HFD2_k127_5944274_0 Family membership K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 295.0
HFD2_k127_5944274_1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000001443 218.0
HFD2_k127_5952668_0 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 397.0
HFD2_k127_5952668_1 - - - - 0.0000000000000000000000000000000000000000000000000007362 196.0
HFD2_k127_5952668_2 Belongs to the methyltransferase superfamily K06969 - 2.1.1.191 0.000000000002068 68.0
HFD2_k127_5953434_0 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000004926 72.0
HFD2_k127_5955682_0 Transcriptional regulator, LysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003366 265.0
HFD2_k127_5960460_0 Regulator of chromosome condensation (RCC1) repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 295.0
HFD2_k127_5960460_1 Acid phosphatase homologues - - - 0.0000000000000000000000000000000000000000000000000006727 199.0
HFD2_k127_5960460_2 OmpA family K03286 - - 0.0000000000000000000000000002506 125.0
HFD2_k127_5961444_0 Protoglobin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006244 446.0
HFD2_k127_5963336_0 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 496.0
HFD2_k127_5963336_1 Arac family - - - 0.0005008 51.0
HFD2_k127_5968999_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000208 269.0
HFD2_k127_5968999_1 WGR domain protein - - - 0.0000000000000000000002524 113.0
HFD2_k127_5968999_2 WGR domain protein - - - 0.00000000000001717 85.0
HFD2_k127_5968999_3 Domain of unknown function (DUF4132) - - - 0.000000000001409 81.0
HFD2_k127_5968999_4 Bacterial regulatory proteins, tetR family - - - 0.000003616 59.0
HFD2_k127_5980461_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 361.0
HFD2_k127_5980461_1 Family membership K12132 - 2.7.11.1 0.00000001358 59.0
HFD2_k127_5982474_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 560.0
HFD2_k127_598261_0 cyclic pyranopterin monophosphate synthase activity K03637,K03639,K20967 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009507,GO:0009536,GO:0009987,GO:0016829,GO:0016830,GO:0016849,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051189,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0061798,GO:0061799,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 4.1.99.22,4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 323.0
HFD2_k127_598261_1 protein trimerization - - - 0.000000000000000000000000000000000000000000000000000000000000000003086 238.0
HFD2_k127_5992620_0 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 291.0
HFD2_k127_5992620_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000002569 156.0
HFD2_k127_59928_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008697 260.0
HFD2_k127_59928_1 - - - - 0.0001077 50.0
HFD2_k127_5997150_0 Diacylglycerol kinase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001383 247.0
HFD2_k127_5997150_1 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000005462 212.0
HFD2_k127_5997150_2 Tetratricopeptide repeat - - - 0.00006763 47.0
HFD2_k127_5997988_0 oxidoreductase activity K07114 - - 0.00000000000000000000000000000000000000000000000305 188.0
HFD2_k127_5999521_0 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 432.0
HFD2_k127_5999721_0 50S ribosome-binding GTPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001999 260.0
HFD2_k127_5999721_1 Protein of unknown function (DUF2786) - - - 0.000000000000000000000000000000000000000000000000001139 190.0
HFD2_k127_5999721_2 PFAM blue (type 1) copper domain protein - - - 0.0000004083 61.0
HFD2_k127_6000683_0 FMN-dependent dehydrogenase K16422 - 1.1.3.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 402.0
HFD2_k127_6000683_1 Eukaryotic integral membrane protein (DUF1751) - - - 0.000000000000000000000000000005932 133.0
HFD2_k127_600084_0 GAF domain - - - 0.000000000000000000000000000000000000000000000000004325 201.0
HFD2_k127_600084_1 - - - - 0.000000000000000000000000924 106.0
HFD2_k127_600084_2 palmitoyl-(protein) hydrolase activity K06999 - - 0.000000001611 63.0
HFD2_k127_600171_0 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000001615 169.0
HFD2_k127_600171_1 Peptidase C14 caspase catalytic subunit p20 - - - 0.000000000000000000000000000000002159 147.0
HFD2_k127_600171_3 cellulose 1,4-beta-cellobiosidase activity K01278,K01727,K03561,K12287,K21449 - 3.4.14.5,4.2.2.1 0.000000005107 66.0
HFD2_k127_6002944_0 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.0000000000000000000000000000000000000000000000000000001215 209.0
HFD2_k127_6002944_1 Belongs to the DNA photolyase family K01669 GO:0000003,GO:0000166,GO:0000719,GO:0001101,GO:0002252,GO:0002376,GO:0003006,GO:0003674,GO:0003824,GO:0003904,GO:0003913,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005773,GO:0006139,GO:0006259,GO:0006281,GO:0006290,GO:0006325,GO:0006338,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006874,GO:0006875,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0007154,GO:0007165,GO:0007275,GO:0007623,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009314,GO:0009414,GO:0009415,GO:0009416,GO:0009605,GO:0009606,GO:0009607,GO:0009615,GO:0009628,GO:0009637,GO:0009638,GO:0009642,GO:0009645,GO:0009646,GO:0009648,GO:0009719,GO:0009725,GO:0009785,GO:0009791,GO:0009881,GO:0009882,GO:0009888,GO:0009893,GO:0009909,GO:0009911,GO:0009987,GO:0010033,GO:0010035,GO:0010073,GO:0010075,GO:0010118,GO:0010228,GO:0010244,GO:0010617,GO:0014070,GO:0016043,GO:0016604,GO:0016829,GO:0016830,GO:0017076,GO:0019222,GO:0019637,GO:0019725,GO:0022414,GO:0022603,GO:0023052,GO:0030003,GO:0030522,GO:0030554,GO:0031323,GO:0031325,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0033993,GO:0034641,GO:0035639,GO:0036094,GO:0038023,GO:0040008,GO:0042221,GO:0042592,GO:0042726,GO:0042752,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044260,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0048037,GO:0048507,GO:0048509,GO:0048511,GO:0048518,GO:0048522,GO:0048571,GO:0048573,GO:0048574,GO:0048580,GO:0048582,GO:0048583,GO:0048608,GO:0048638,GO:0048731,GO:0048831,GO:0048856,GO:0048878,GO:0050660,GO:0050662,GO:0050789,GO:0050793,GO:0050794,GO:0050801,GO:0050896,GO:0051094,GO:0051186,GO:0051239,GO:0051240,GO:0051276,GO:0051480,GO:0051607,GO:0051704,GO:0051707,GO:0051716,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055086,GO:0060089,GO:0061458,GO:0065007,GO:0065008,GO:0070013,GO:0071214,GO:0071478,GO:0071482,GO:0071483,GO:0071704,GO:0071840,GO:0071949,GO:0072387,GO:0072503,GO:0072507,GO:0090304,GO:0097159,GO:0097367,GO:0098542,GO:0098771,GO:0104004,GO:0140097,GO:1900618,GO:1901265,GO:1901360,GO:1901363,GO:1901371,GO:1901564,GO:1901700,GO:1902347,GO:1905421,GO:2000024,GO:2000026,GO:2000028,GO:2000241,GO:2000243,GO:2000377,GO:2000379 4.1.99.3 0.0000000000000000000000000000000000000000000000000006773 190.0
HFD2_k127_6006040_0 Protein kinase domain K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005479 329.0
HFD2_k127_6006040_1 amino acid K01999,K11954 - - 0.00000000000000000000000000000000000000000001534 181.0
HFD2_k127_6006040_2 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000531 63.0
HFD2_k127_6009184_0 Prokaryotic glutathione synthetase, ATP-grasp domain K03802 - 6.3.2.29,6.3.2.30 2.454e-255 799.0
HFD2_k127_6009184_1 Fungalysin/Thermolysin Propeptide Motif K01400 GO:0005575,GO:0005576 3.4.24.28 0.000000000000000000000000000000000000000000006109 183.0
HFD2_k127_6009184_2 Alpha-tubulin suppressor and related RCC1 domain-containing proteins - - - 0.000000000000000000000000000008112 134.0
HFD2_k127_6011628_0 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.00000000000000000000000000000000000000000000000000000000006433 211.0
HFD2_k127_6011628_1 Dimerisation domain of d-ornithine 4,5-aminomutase K18011 - 5.4.3.3 0.0000000000000000000000000000000000000000001934 160.0
HFD2_k127_6011628_2 BFD-like [2Fe-2S] binding domain K02192 - - 0.0000006023 54.0
HFD2_k127_6014413_0 Aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 356.0
HFD2_k127_6014413_1 Homocysteine S-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009058 283.0
HFD2_k127_6014413_2 regulator of chromosome condensation, RCC1 - - - 0.000000000000000000000001484 115.0
HFD2_k127_6025229_0 PilT protein domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009541 301.0
HFD2_k127_6025229_1 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000004233 134.0
HFD2_k127_6030745_0 Bacterial virulence factor lipase N-terminal - - - 0.00000000003285 76.0
HFD2_k127_6036467_0 WGR domain protein - - - 0.000000000000000000000002974 113.0
HFD2_k127_6036467_1 - - - - 0.0000004921 63.0
HFD2_k127_6036887_0 Flagellar Motor Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005366 604.0
HFD2_k127_6036887_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. K07636 - 2.7.13.3 0.0000000000000000000000000000002019 135.0
HFD2_k127_6036887_2 carboxylic ester hydrolase activity K12132 - 2.7.11.1 0.000000000000000002097 89.0
HFD2_k127_6043033_0 uridine kinase K00876 - 2.7.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 479.0
HFD2_k127_6045347_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009293 364.0
HFD2_k127_6045347_1 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000009894 123.0
HFD2_k127_6045347_2 SMART Integrin alpha beta-propellor repeat protein - - - 0.00000002057 66.0
HFD2_k127_6049056_0 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 338.0
HFD2_k127_6049056_1 Glycoside hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004488 269.0
HFD2_k127_6057121_0 tRNA nucleotidyltransferase domain 2 putative K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006123 550.0
HFD2_k127_6057121_1 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane K18093 - - 0.0000000000000000000000000000000000000000000001638 179.0
HFD2_k127_6057121_2 Acyl-CoA dehydrogenase, C-terminal domain K00249,K11731 - 1.3.8.7 0.000000000000000000000000000006914 118.0
HFD2_k127_6057882_0 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003723 301.0
HFD2_k127_6057882_1 4Fe-4S binding domain - - - 0.00000000000000000000000000000000005356 140.0
HFD2_k127_6058354_0 Zn-dependent hydrolases including glyoxylases - - - 0.000000000000000000000000000000000000000000000000002097 201.0
HFD2_k127_6058354_1 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000004206 109.0
HFD2_k127_6062084_0 coproporphyrinogen oxidase activity K21936 - 2.1.1.342 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009752 392.0
HFD2_k127_6062084_1 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000007088 194.0
HFD2_k127_6075143_0 Bacterial regulatory protein, Fis family K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 439.0
HFD2_k127_6075143_1 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001147 255.0
HFD2_k127_6077627_0 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008619 379.0
HFD2_k127_6077627_1 Stress-induced bacterial acidophilic repeat motif K06884 - - 0.000000000001793 72.0
HFD2_k127_6078521_0 Carbamoyltransferase C-terminus K00612 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 515.0
HFD2_k127_6080588_0 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.0000000000000000000000000000000000000000000000000000002732 205.0
HFD2_k127_608493_1 Asparaginase K13051 - 3.4.19.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 389.0
HFD2_k127_608493_2 phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases large terminal subunit K00479,K00499 - 1.14.15.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 350.0
HFD2_k127_6090757_0 Response regulator receiver K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003598 317.0
HFD2_k127_6092476_0 WGR domain protein - - - 0.00000000000000000003778 106.0
HFD2_k127_6092476_1 Domain of unknown function (DUF4132) - - - 0.00000000000007141 85.0
HFD2_k127_6092476_2 transcriptional activator domain - - - 0.0000003014 64.0
HFD2_k127_6092476_3 Transcriptional regulator - - - 0.0000009244 56.0
HFD2_k127_6092476_4 Parallel beta-helix repeats - - - 0.00006429 56.0
HFD2_k127_6098317_0 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 501.0
HFD2_k127_6098317_1 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784,K12448 - 5.1.3.2,5.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 394.0
HFD2_k127_6098317_2 3-beta hydroxysteroid dehydrogenase/isomerase family K08678 - 4.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 355.0
HFD2_k127_6101192_0 Glucose / Sorbosone dehydrogenase - - - 2.572e-211 679.0
HFD2_k127_6101720_0 May be involved in the transport of PQQ or its precursor to the periplasm K06136 GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0018130,GO:0018189,GO:0018193,GO:0018212,GO:0019538,GO:0019752,GO:0034641,GO:0036211,GO:0042180,GO:0042181,GO:0042364,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072350,GO:0072351,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901661,GO:1901663 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004479 284.0
HFD2_k127_6112399_0 XdhC Rossmann domain K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 326.0
HFD2_k127_6112399_2 - - - - 0.0000000000000000000000000000000000000000000000000000000001508 205.0
HFD2_k127_6112399_3 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase - - - 0.000000000000000000000000009941 122.0
HFD2_k127_6112399_4 Chagasin family peptidase inhibitor I42 K14475 - - 0.00000000005068 69.0
HFD2_k127_6115318_0 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 387.0
HFD2_k127_6115318_1 PFAM amidohydrolase K20810 - 3.5.4.40 0.00000000000000000000000000000000000000000000000000000001232 215.0
HFD2_k127_611581_0 Sodium:solute symporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006277 289.0
HFD2_k127_611581_1 - - - - 0.000000000000000000000000000000000000000000000000002205 193.0
HFD2_k127_6119337_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 561.0
HFD2_k127_6119337_1 SurA N-terminal domain K03771 - 5.2.1.8 0.0000000000003293 79.0
HFD2_k127_6130785_0 - - - - 0.000000000000000000000000000000000000002826 158.0
HFD2_k127_6130785_1 - - - - 0.00000000000000000001526 98.0
HFD2_k127_6135004_0 Tetratricopeptide repeat - - - 0.0 1262.0
HFD2_k127_6135004_1 Domain of unknown function (DUF374) K09778 - - 0.0000000000000000000000000006338 122.0
HFD2_k127_6135004_2 endoribonuclease L-PSP K09022 - 3.5.99.10 0.000006361 48.0
HFD2_k127_613951_0 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.000000000000000000000000000000000000000000000000000457 205.0
HFD2_k127_6150675_0 synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 432.0
HFD2_k127_6150675_1 response regulator - - - 0.0001195 53.0
HFD2_k127_6157363_0 Putative amidoligase enzyme (DUF2126) - - - 0.0 1397.0
HFD2_k127_6157363_1 Circularly permuted ATP-grasp type 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 453.0
HFD2_k127_6157505_0 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000001974 168.0
HFD2_k127_6159793_0 metalloendopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000002358 218.0
HFD2_k127_6160440_0 PHP domain protein - - - 3.826e-211 692.0
HFD2_k127_6161299_0 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000004893 229.0
HFD2_k127_6161299_1 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000003897 149.0
HFD2_k127_6161299_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000009336 58.0
HFD2_k127_6181360_0 Vault protein inter-alpha-trypsin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 478.0
HFD2_k127_6181360_1 glucosidase activity - - - 0.00000000000001329 86.0
HFD2_k127_618770_0 Family membership K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000755 246.0
HFD2_k127_618770_1 - - - - 0.00000000000000000000000001288 116.0
HFD2_k127_618770_2 peptidyl-tyrosine sulfation - - - 0.000000000000009519 87.0
HFD2_k127_6190666_0 SEC-C Motif Domain Protein K09858 - - 0.00000000000000000000000002174 116.0
HFD2_k127_6191082_0 pyrroloquinoline quinone binding - - - 0.0000000000000000000000000000000000000000000000000000000000000004987 236.0
HFD2_k127_6191082_1 Pfam Hemerythrin HHE cation binding domain - - - 0.000000002194 59.0
HFD2_k127_6192287_0 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000009096 169.0
HFD2_k127_6192287_1 protein with a C-terminal OMP (outer membrane protein) domain - - - 0.0000000006728 68.0
HFD2_k127_6196161_0 general secretion pathway protein K02456 - - 0.000000000000001156 84.0
HFD2_k127_6196161_1 Protein of unknown function (DUF3750) - - - 0.00000000000007598 85.0
HFD2_k127_6196161_2 Protease, serine 56 - GO:0001654,GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0006508,GO:0006807,GO:0007275,GO:0007423,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0012505,GO:0016787,GO:0017171,GO:0019538,GO:0032501,GO:0032502,GO:0043010,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0048513,GO:0048731,GO:0048856,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.0009364 50.0
HFD2_k127_6197425_0 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 359.0
HFD2_k127_6197425_1 PFAM NAD dependent epimerase dehydratase family K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000003013 239.0
HFD2_k127_6197425_2 - - - - 0.0000000000000003581 92.0
HFD2_k127_6197425_3 - - - - 0.00000698 50.0
HFD2_k127_6197425_4 Sporulation protein YtfJ (Spore_YtfJ) - - - 0.0000161 54.0
HFD2_k127_6199983_0 Signal transducing histidine kinase, homodimeric K03407 - 2.7.13.3 0.000003133 55.0
HFD2_k127_6199983_1 Alpha amylase, catalytic domain - - - 0.00009773 55.0
HFD2_k127_6203124_0 COG0187 Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) B subunit K02470,K02622 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009685 399.0
HFD2_k127_6203124_1 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009034 277.0
HFD2_k127_6204103_0 3-demethylubiquinone-9 3-methyltransferase K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 299.0
HFD2_k127_6204103_2 alpha/beta hydrolase fold - - - 0.00000004277 65.0
HFD2_k127_6204103_3 - - - - 0.00000004624 58.0
HFD2_k127_6206686_0 CGMP-dependent 3',5'-cGMP phosphodiesterase. Source PGD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 419.0
HFD2_k127_6206686_1 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006081 329.0
HFD2_k127_6213168_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006591 399.0
HFD2_k127_6213168_1 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.0000000000000000000000000000000000000000000000001731 182.0
HFD2_k127_6213168_2 Cysteine-rich domain - - - 0.00000000000000000000000000002366 120.0
HFD2_k127_6219050_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000927 76.0
HFD2_k127_6223350_0 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 490.0
HFD2_k127_6223939_0 Phosphodiesterase alkaline phosphatase D K01113 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 498.0
HFD2_k127_6229045_0 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007929 268.0
HFD2_k127_6230783_0 DbpA RNA binding domain K05592 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 474.0
HFD2_k127_6230783_1 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000269 297.0
HFD2_k127_6230783_2 AAC-rich mRNA clone AAC4 protein-like - - - 0.00000000000000000000000001748 121.0
HFD2_k127_6230783_3 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000005662 86.0
HFD2_k127_6231561_0 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000811 302.0
HFD2_k127_6231561_1 Purple acid Phosphatase, N-terminal domain - - - 0.0000000000000000000000000000000000000127 162.0
HFD2_k127_6238566_0 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 305.0
HFD2_k127_6238566_1 ABC-2 family transporter protein - - - 0.00000000000000001282 91.0
HFD2_k127_6243232_0 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 445.0
HFD2_k127_6243232_1 Belongs to the N(4) N(6)-methyltransferase family K00571 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 315.0
HFD2_k127_6243232_2 Penicillin-insensitive murein endopeptidase K07261 - - 0.000000000000000000000000000000000000000000000000000000000000000000008343 244.0
HFD2_k127_6243232_3 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.0000000000000000000000000000004289 130.0
HFD2_k127_6244477_0 nucleotidyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009238 254.0
HFD2_k127_6244477_1 Bulb-type mannose-specific lectin - - - 0.000000000000000000000001019 112.0
HFD2_k127_6244477_2 Phosphomevalonate kinase K13273 - 2.7.4.2 0.00000000001098 73.0
HFD2_k127_6244477_3 - - - - 0.00001035 55.0
HFD2_k127_624516_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000003975 221.0
HFD2_k127_624516_1 AAA ATPase domain - - - 0.00007003 55.0
HFD2_k127_625219_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 584.0
HFD2_k127_625219_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002722 246.0
HFD2_k127_625219_2 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000000000000007082 177.0
HFD2_k127_625219_3 ATPases associated with a variety of cellular activities K02056,K10441,K17210 - 3.6.3.17 0.000000006512 61.0
HFD2_k127_6253867_0 SMART Elongator protein 3 MiaB NifB - - - 0.0 1101.0
HFD2_k127_6253867_1 - - - - 0.00000000000002191 84.0
HFD2_k127_6253867_2 DUF3160 - - - 0.00000067 61.0
HFD2_k127_625460_0 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 507.0
HFD2_k127_625460_1 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 456.0
HFD2_k127_625460_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 436.0
HFD2_k127_625460_3 Sulfatase K01133 - 3.1.6.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008388 344.0
HFD2_k127_625460_4 exo-alpha-(2->6)-sialidase activity K01186 GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509 3.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000005741 240.0
HFD2_k127_625460_5 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000000000000000000001668 128.0
HFD2_k127_625460_6 protein conserved in bacteria - - - 0.00000000000000000000000006523 122.0
HFD2_k127_625460_7 acetyltransferases and hydrolases with the alpha beta hydrolase fold K01046 - 3.1.1.3 0.0000000000000000000006741 109.0
HFD2_k127_625460_8 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000473 81.0
HFD2_k127_6265606_0 PLD-like domain - - - 0.000000000000000000000000000000000000003323 160.0
HFD2_k127_6265606_1 Nucleoside-diphosphate-sugar epimerases - - - 0.00000003855 57.0
HFD2_k127_6265606_2 amine dehydrogenase activity - - - 0.0000009868 53.0
HFD2_k127_6266501_0 Aldehyde dehydrogenase family K00128,K00154 - 1.2.1.3,1.2.1.68 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 505.0
HFD2_k127_6266501_1 Protein of unknown function (DUF2914) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 438.0
HFD2_k127_6266501_2 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 309.0
HFD2_k127_6266501_3 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000001011 249.0
HFD2_k127_6266501_4 PFAM Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000004605 190.0
HFD2_k127_6266501_5 TM2 domain - - - 0.000000000000000000000000000000003712 134.0
HFD2_k127_6266501_6 TIGRFAM Raf kinase inhibitor-like protein, YbhB YbcL family K06910 - - 0.0000000000000000000005106 104.0
HFD2_k127_6266501_7 Protein of unknown function (DUF1232) - - - 0.0000000002906 65.0
HFD2_k127_6267173_0 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000000000000000000000000000000000000000000000001379 194.0
HFD2_k127_6272009_0 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 469.0
HFD2_k127_6272009_1 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000647 362.0
HFD2_k127_6272009_2 Domain of Unknown Function (DUF1259) - - - 0.0000000000000000000006123 112.0
HFD2_k127_6272009_3 protein kinase activity - - - 0.00000000000003936 75.0
HFD2_k127_6282123_0 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000001072 235.0
HFD2_k127_6290686_0 Uncharacterized conserved protein (DUF2293) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 304.0
HFD2_k127_6290686_1 Cytochrome c K08685 - 1.4.9.1 0.0000000000000000000000000000000001994 137.0
HFD2_k127_6291301_0 Collagenase K08303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004972 535.0
HFD2_k127_629138_0 type IV pilus secretin PilQ K02666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 434.0
HFD2_k127_629200_0 M18 family aminopeptidase K01267 GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.11.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 432.0
HFD2_k127_629200_1 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000002213 117.0
HFD2_k127_629531_0 DMT(Drug metabolite transporter) superfamily permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 333.0
HFD2_k127_629531_1 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000002026 204.0
HFD2_k127_629531_2 acetylesterase activity - - - 0.0000000000000000000000000000000000000001542 162.0
HFD2_k127_6298385_0 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 386.0
HFD2_k127_6298385_1 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000005 207.0
HFD2_k127_6298385_2 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000001818 129.0
HFD2_k127_6298385_3 GAF domain - - - 0.000000000000000000000000003918 116.0
HFD2_k127_6298385_5 Protein of unknown function (DUF533) K06596 - - 0.000006674 55.0
HFD2_k127_6299525_0 PFAM Prenyltransferase squalene oxidase K06045 - 4.2.1.129,5.4.99.17 0.00000000000000000000000456 113.0
HFD2_k127_6301576_0 - - - - 1.084e-203 664.0
HFD2_k127_6301576_1 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000001006 237.0
HFD2_k127_6301576_2 FtsX-like permease family - - - 0.0000000000000000000000000000000000000007167 153.0
HFD2_k127_6301576_3 ATP-dependent protease La (LON) substrate-binding domain K01338,K07157 - 3.4.21.53 0.000000000000000000000000000000000000002586 155.0
HFD2_k127_6301576_4 GTP cyclohydrolase I K01495 - 3.5.4.16 0.0000000000000000000000000000000000004552 147.0
HFD2_k127_6301576_5 Uncharacterized conserved protein (DUF2203) - - - 0.000000000000000000000000000000000009812 141.0
HFD2_k127_6301576_6 Rieske-like [2Fe-2S] domain K05710 - - 0.00000000000349 71.0
HFD2_k127_6305273_0 PFAM Glycosyl transferase, family 2 K11936 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 379.0
HFD2_k127_6305273_1 polysaccharide deacetylase - - - 0.00000005153 65.0
HFD2_k127_6305760_0 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005134 296.0
HFD2_k127_6305760_1 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000001638 224.0
HFD2_k127_6305760_4 FIST C domain - - - 0.0000000000000000002017 102.0
HFD2_k127_6305760_5 Tetratricopeptide repeat - - - 0.00000000000000002695 93.0
HFD2_k127_6306059_0 Belongs to the glycosyl hydrolase 13 family - - - 0.00000000000000000002413 100.0
HFD2_k127_6306059_1 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.00000000000002739 87.0
HFD2_k127_6306059_2 Papain fold toxin 1, glutamine deamidase K01126 - 3.1.4.46 0.000000000772 69.0
HFD2_k127_6306059_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00007461 51.0
HFD2_k127_6313513_0 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.0000000000000000000004804 100.0
HFD2_k127_6313513_1 HEPN domain - - - 0.000000000006813 77.0
HFD2_k127_6313513_2 Nucleotidyltransferase domain K07076 - - 0.00000002341 59.0
HFD2_k127_6313513_3 - - - - 0.0002036 47.0
HFD2_k127_631528_0 Belongs to the glycosyl hydrolase 31 family K01811,K15922 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006790,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016787,GO:0016798,GO:0019637,GO:0034308,GO:0042180,GO:0044237,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0061720,GO:0071704,GO:1901135,GO:1901136,GO:1901575,GO:1901615,GO:1902776,GO:1902777,GO:1990929 3.2.1.177,3.2.1.199 0.00000000000000000000000000000000000000000000000005193 191.0
HFD2_k127_631528_1 Peptidase C26 K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000662 196.0
HFD2_k127_631528_2 Lipase maturation factor - - - 0.000000000000000000000000000000000000003079 161.0
HFD2_k127_6325478_0 histone H2A K63-linked ubiquitination - - - 0.00001484 53.0
HFD2_k127_63285_0 Belongs to the peptidase S1B family - - - 0.00000000000000000000000000000000000001575 160.0
HFD2_k127_63285_2 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.0000000003086 66.0
HFD2_k127_63285_3 Dehydrogenase - - - 0.000006224 59.0
HFD2_k127_6328745_0 PFAM Acetyltransferase (GNAT) family K06976 - - 0.0000000000000000000000000000000000000000000000000000000002357 215.0
HFD2_k127_6328745_1 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000000000000000000000000000000007821 213.0
HFD2_k127_6333706_0 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 367.0
HFD2_k127_6333706_1 FHA domain - - - 0.00000000000000000000007767 100.0
HFD2_k127_6333706_2 thiolester hydrolase activity - - - 0.000000000000000000642 91.0
HFD2_k127_6333706_3 Cupin 2, conserved barrel domain protein K07506 - - 0.000000000000195 78.0
HFD2_k127_6335081_0 Acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000005471 213.0
HFD2_k127_6335081_1 thiolester hydrolase activity - - - 0.00000000000000000000000000000000000000001627 170.0
HFD2_k127_6335574_0 pyrroloquinoline quinone binding - - - 0.0000000005807 66.0
HFD2_k127_6335574_1 - - - - 0.000000005 67.0
HFD2_k127_6356027_0 trisaccharide binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 570.0
HFD2_k127_6356027_1 PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004042 503.0
HFD2_k127_6356027_2 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 314.0
HFD2_k127_6357123_0 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000003913 241.0
HFD2_k127_6357123_1 - - - - 0.00000000000000000000000000000000000000000000000000003645 209.0
HFD2_k127_6357123_2 PFAM Dopa 4,5-dioxygenase family K10253 - - 0.0000000000000000000000000000000000000000003724 160.0
HFD2_k127_6357813_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 2.237e-294 925.0
HFD2_k127_6359227_0 adenosine deaminase K01488 - 3.5.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000001965 256.0
HFD2_k127_6359227_1 CarboxypepD_reg-like domain - - - 0.00007231 54.0
HFD2_k127_6360291_0 MatE K03327 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 399.0
HFD2_k127_6361355_0 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000368 606.0
HFD2_k127_6361355_1 Protein of unknown function (DUF3570) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009697 344.0
HFD2_k127_6361355_2 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000002872 145.0
HFD2_k127_6361355_4 - - - - 0.00000000000000000000000001014 124.0
HFD2_k127_6361355_6 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.000000000000000000003355 105.0
HFD2_k127_6362014_0 mevalonate kinase K00869 - 2.7.1.36 0.0000000000000000000000000000000000000000000006297 179.0
HFD2_k127_6362014_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000001216 138.0
HFD2_k127_6362014_2 palmitoyl-(protein) hydrolase activity - - - 0.000000000000000000000000002421 117.0
HFD2_k127_6362014_3 Transcriptional regulator K05799,K13637 - - 0.0000000000000000000004426 108.0
HFD2_k127_6370733_0 Dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000005287 233.0
HFD2_k127_6370733_1 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000005326 160.0
HFD2_k127_6370733_2 ROK family K00845 - 2.7.1.2 0.0000005483 56.0
HFD2_k127_6371173_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000805 489.0
HFD2_k127_6371721_0 Protein of unknown function (DUF1553) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002284 267.0
HFD2_k127_6371721_1 Phosphate acyltransferases - - - 0.00000000000000000000000000000000005901 149.0
HFD2_k127_637477_0 AAA C-terminal domain K07478 - - 0.000000000000000000000000000000000000000000001105 173.0
HFD2_k127_637477_1 Cellulose synthase K20543 - - 0.0000001851 64.0
HFD2_k127_637477_2 histone H2A K63-linked ubiquitination - - - 0.00001624 57.0
HFD2_k127_6380211_0 cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 574.0
HFD2_k127_6380211_1 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 303.0
HFD2_k127_6380211_2 LysR substrate binding domain protein K04761 - - 0.00000007956 58.0
HFD2_k127_6383016_0 phosphorelay signal transduction system K10941,K21405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008429 474.0
HFD2_k127_6383016_1 protein kinase activity - - - 0.000000000000000000000000000000000000000000005366 173.0
HFD2_k127_6383016_2 Bacterial virulence factor lipase N-terminal - - - 0.000000000000000002741 100.0
HFD2_k127_6383016_3 WD40-like Beta Propeller Repeat - - - 0.0000000000002342 79.0
HFD2_k127_6388273_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000001184 254.0
HFD2_k127_6388273_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000002688 144.0
HFD2_k127_6388273_2 Protein serine threonine phosphatase K20074 - 3.1.3.16 0.00000000000000000000000000023 115.0
HFD2_k127_6388273_3 Hsp20/alpha crystallin family K13993 - - 0.000000000000000005883 96.0
HFD2_k127_6388273_4 Protein kinase domain K12132 - 2.7.11.1 0.00000001644 64.0
HFD2_k127_638993_0 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002866 317.0
HFD2_k127_638993_1 Parallel beta-helix repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005156 284.0
HFD2_k127_638993_2 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000001995 248.0
HFD2_k127_638993_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000004565 151.0
HFD2_k127_638993_4 Domain of unknown function (DUF4331) - - - 0.0000000000000000564 89.0
HFD2_k127_6391908_0 MFS transporter K11381 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000957 570.0
HFD2_k127_6391908_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000001757 223.0
HFD2_k127_6391908_2 Protein of unknown function (DUF1778) - - - 0.0000000000000000000000000000003428 124.0
HFD2_k127_6395385_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 317.0
HFD2_k127_6398103_0 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000003284 241.0
HFD2_k127_6398103_1 ubiquinone biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000005937 222.0
HFD2_k127_6398103_2 membrane K08988 - - 0.00000000000000003537 89.0
HFD2_k127_6399558_0 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000001536 216.0
HFD2_k127_6399558_1 Protein kinase domain - - - 0.00000000000000000002464 107.0
HFD2_k127_6404721_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 416.0
HFD2_k127_6404721_1 Belongs to the peptidase S1B family - - - 0.0000000000000000000000000002051 128.0
HFD2_k127_6404721_2 arsenate reductase (glutaredoxin) activity K00537 - 1.20.4.1 0.0000000000000003467 78.0
HFD2_k127_6404721_3 Uncharacterized protein conserved in bacteria (DUF2330) - - - 0.00004851 50.0
HFD2_k127_6410509_0 Zn_pept - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 608.0
HFD2_k127_6416707_0 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 335.0
HFD2_k127_6416707_1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00015 - 1.1.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000625 306.0
HFD2_k127_6416707_2 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000005498 165.0
HFD2_k127_6419503_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 329.0
HFD2_k127_6419503_1 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 307.0
HFD2_k127_6419503_2 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000001379 217.0
HFD2_k127_6419823_0 - - - - 9.83e-322 1037.0
HFD2_k127_6419823_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 557.0
HFD2_k127_6419823_2 MAPEG family K00799 GO:0000003,GO:0000323,GO:0001775,GO:0002237,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003006,GO:0003674,GO:0003824,GO:0004364,GO:0004601,GO:0004602,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005764,GO:0005765,GO:0005766,GO:0005773,GO:0005774,GO:0005777,GO:0005778,GO:0005783,GO:0005789,GO:0005886,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006805,GO:0006807,GO:0006810,GO:0006887,GO:0006950,GO:0006955,GO:0006979,GO:0006982,GO:0007275,GO:0007548,GO:0008150,GO:0008152,GO:0008406,GO:0008584,GO:0009058,GO:0009410,GO:0009605,GO:0009607,GO:0009617,GO:0009636,GO:0009987,GO:0010033,GO:0010243,GO:0012505,GO:0012506,GO:0016020,GO:0016021,GO:0016043,GO:0016192,GO:0016209,GO:0016491,GO:0016684,GO:0016740,GO:0016765,GO:0019867,GO:0022414,GO:0022607,GO:0030141,GO:0030154,GO:0030659,GO:0030667,GO:0031090,GO:0031224,GO:0031410,GO:0031903,GO:0031966,GO:0031967,GO:0031968,GO:0031975,GO:0031982,GO:0031984,GO:0032496,GO:0032501,GO:0032502,GO:0032940,GO:0033194,GO:0033218,GO:0033327,GO:0033554,GO:0033993,GO:0034599,GO:0034641,GO:0035577,GO:0036230,GO:0042119,GO:0042175,GO:0042221,GO:0042277,GO:0042493,GO:0042579,GO:0042582,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043295,GO:0043299,GO:0043312,GO:0043603,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044272,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044432,GO:0044433,GO:0044437,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045137,GO:0045177,GO:0045321,GO:0046546,GO:0046661,GO:0046903,GO:0046983,GO:0048037,GO:0048513,GO:0048608,GO:0048731,GO:0048856,GO:0048869,GO:0050896,GO:0051179,GO:0051186,GO:0051234,GO:0051259,GO:0051260,GO:0051704,GO:0051707,GO:0051716,GO:0055114,GO:0061458,GO:0065003,GO:0070206,GO:0070207,GO:0070887,GO:0071447,GO:0071449,GO:0071466,GO:0071704,GO:0071840,GO:0071944,GO:0072341,GO:0097237,GO:0097708,GO:0098588,GO:0098754,GO:0098805,GO:0098827,GO:0098852,GO:0098869,GO:0099503,GO:1900750,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1901685,GO:1901687,GO:1901698,GO:1901700,GO:1901701,GO:1990748 2.5.1.18 0.000000000000000000008488 98.0
HFD2_k127_6419823_3 Bacterial regulatory proteins, tetR family - - - 0.0000003236 58.0
HFD2_k127_6435024_0 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 312.0
HFD2_k127_6435024_1 OPT oligopeptide transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008258 261.0
HFD2_k127_6435024_2 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000007975 218.0
HFD2_k127_6435024_3 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000005607 221.0
HFD2_k127_6435024_4 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.0000000000000000000000000000000000000000002205 166.0
HFD2_k127_6438436_0 Protein conserved in bacteria - - - 0.000000000000001273 86.0
HFD2_k127_6438436_1 - - - - 0.00002068 48.0
HFD2_k127_64422_0 COG1073 hydrolases of the alpha beta superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 317.0
HFD2_k127_64422_1 Long-chain fatty acid transport protein K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 308.0
HFD2_k127_64422_2 Catalase - - - 0.0000000000000000000000000000000000000000228 169.0
HFD2_k127_6448979_0 AMP-binding enzyme K01897 - 6.2.1.3 8.341e-224 709.0
HFD2_k127_6448979_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 546.0
HFD2_k127_6448979_2 saccharopine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006673 406.0
HFD2_k127_6448979_3 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000001105 84.0
HFD2_k127_6452247_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003229 333.0
HFD2_k127_6452247_1 MAPEG family - - - 0.000000000000000000000000000000000005742 145.0
HFD2_k127_6452811_0 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000005238 248.0
HFD2_k127_6452811_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000001065 184.0
HFD2_k127_6452811_2 - - - - 0.00000000000000000000000000002909 134.0
HFD2_k127_6452811_3 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.00000000000000000000000000004626 125.0
HFD2_k127_6453079_0 Family membership K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008977 289.0
HFD2_k127_6453079_1 iron ion transport K07224 - - 0.000000000000000000000005215 106.0
HFD2_k127_6453079_2 protein trimerization - - - 0.00000002683 66.0
HFD2_k127_6453079_3 Cytochrome c - - - 0.0003927 49.0
HFD2_k127_6453090_0 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000004097 239.0
HFD2_k127_6453090_1 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000000000000000000000000001726 137.0
HFD2_k127_6453090_2 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000000000000163 88.0
HFD2_k127_6453090_3 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000002967 75.0
HFD2_k127_6454168_0 Protein kinase domain K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003034 559.0
HFD2_k127_6454168_1 Family membership K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000194 290.0
HFD2_k127_6454168_2 phosphate ion binding - - - 0.00000000000000000000000000000000000000000000000000000000000000004869 243.0
HFD2_k127_6454168_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000001323 122.0
HFD2_k127_6454168_4 Lipase (class 3) K01046 - 3.1.1.3 0.000000001753 70.0
HFD2_k127_6456134_0 protein involved in exopolysaccharide biosynthesis K16554 - - 2.258e-195 636.0
HFD2_k127_6457385_0 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 334.0
HFD2_k127_6457385_1 short chain dehydrogenase reductase family K07124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006652 266.0
HFD2_k127_6457385_2 Hydrolase of the alpha beta-hydrolase K07020 - - 0.000000000000000000000000000000000001553 149.0
HFD2_k127_6457385_3 Peptidase family M50 - - - 0.000000000000000000000000001725 124.0
HFD2_k127_6457385_4 TIGRFAM diguanylate cyclase (GGDEF) domain K21019 - 2.7.7.65 0.00000000000000000000009423 109.0
HFD2_k127_6457385_5 - - - - 0.0000000000000000007377 99.0
HFD2_k127_6457385_6 Response regulator receiver domain - - - 0.00000000000007904 79.0
HFD2_k127_6457385_7 PFAM Mo-dependent nitrogenase - - - 0.000002652 56.0
HFD2_k127_6477032_0 Zinc finger domain - - - 0.0000000000000000000000000000000000000000000000000000001459 205.0
HFD2_k127_6477032_1 Zinc finger domain - - - 0.000000000000000000000000000001571 123.0
HFD2_k127_6477762_0 Alpha amylase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004089 471.0
HFD2_k127_6477762_1 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 295.0
HFD2_k127_6479727_0 O-Antigen Polymerase K02847 - - 0.000000000000000000000000000000000000000000000000000000000000000000007449 245.0
HFD2_k127_6479727_1 - - - - 0.0000000000000000000000000000000000000000000000000000000003101 219.0
HFD2_k127_6479727_2 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695,K03696 - - 0.0000000002948 64.0
HFD2_k127_6480875_0 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000002804 239.0
HFD2_k127_6480875_1 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000003414 79.0
HFD2_k127_6490340_0 Caspase domain - - - 0.00000000000000000000000000000000002715 149.0
HFD2_k127_6490340_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000002848 59.0
HFD2_k127_6490340_2 AntiSigma factor - - - 0.0002624 53.0
HFD2_k127_6499377_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000572 313.0
HFD2_k127_6499377_1 Aminotransferase - - - 0.0000000000008448 68.0
HFD2_k127_6499377_2 Aminoglycoside phosphotransferase - - - 0.000003549 49.0
HFD2_k127_6505858_0 alpha beta - - - 2.958e-201 651.0
HFD2_k127_6505858_2 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000004684 128.0
HFD2_k127_6505858_3 protein kinase activity - - - 0.0000000000000001791 84.0
HFD2_k127_6508517_0 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.00000000000000000000000000000000000000000000000000000000000000000002366 239.0
HFD2_k127_6508517_1 Uncharacterized protein conserved in bacteria (DUF2330) - - - 0.000000000000000000000000000000000000000000000000000000000000003337 235.0
HFD2_k127_6510021_0 PFAM regulator of chromosome condensation, RCC1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001347 282.0
HFD2_k127_6510021_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342,K03703,K04096 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 2.7.7.7 0.0000000000000000000000000000000000000000000000000005973 207.0
HFD2_k127_6510021_2 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000001252 179.0
HFD2_k127_6510021_3 Domain of unknown function (DUF4440) - - - 0.000000000000000000000000000000000000000000007075 166.0
HFD2_k127_6510021_4 Peptidase M50B-like - - - 0.0000000000000000000000000000000000001201 153.0
HFD2_k127_6510021_5 peptidyl-tyrosine sulfation - - - 0.000000002 64.0
HFD2_k127_6511449_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 451.0
HFD2_k127_6511449_1 amino acid ABC transporter, ATP-binding protein K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003874 390.0
HFD2_k127_6511449_2 Stringent starvation protein B K03600 - - 0.00000000000000000000000000000000000001512 156.0
HFD2_k127_6530757_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003555 287.0
HFD2_k127_6533197_0 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 351.0
HFD2_k127_6533197_1 domain protein - - - 0.000000000000000000000000001567 129.0
HFD2_k127_6535869_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.858e-261 816.0
HFD2_k127_6535869_1 response regulator K02481,K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 363.0
HFD2_k127_6535869_2 ABC transporter, ATP-binding protein K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000642 237.0
HFD2_k127_6545063_0 PFAM response regulator receiver K07657 - - 0.0000000000000000000000000000000000000000000000000000000000001613 223.0
HFD2_k127_6545063_1 Histidine kinase - - - 0.000000000000000000000000000000000000005993 164.0
HFD2_k127_6545063_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0001171 48.0
HFD2_k127_6551140_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006231 385.0
HFD2_k127_6551140_1 Protein of unknown function (DUF3501) - - - 0.00000000000000000000000000000000000000000000006813 177.0
HFD2_k127_6551140_2 Thioesterase-like superfamily K01075 - 3.1.2.23 0.00000000000000000000000000000000000003217 147.0
HFD2_k127_655513_0 Circularly permuted ATP-grasp type 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 493.0
HFD2_k127_655513_1 PFAM Bacterial domain of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 412.0
HFD2_k127_655513_2 alpha beta - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 401.0
HFD2_k127_655513_3 deoxyhypusine monooxygenase activity - - - 0.0000000000002208 81.0
HFD2_k127_6556854_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 445.0
HFD2_k127_6556854_1 Glycosyl hydrolases family 43 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003011 276.0
HFD2_k127_6556854_2 acid phosphatase activity K01179,K21449 - 3.2.1.4 0.00000000000000000001901 106.0
HFD2_k127_6556854_3 Domain of unknown function (DUF3332) - - - 0.000000000000000904 89.0
HFD2_k127_6559659_0 PFAM cobalamin adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000000000000000000000000000001116 191.0
HFD2_k127_6564056_0 Zinc finger, swim domain protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 411.0
HFD2_k127_6564056_1 VWA domain containing CoxE-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 283.0
HFD2_k127_6566589_0 Family membership K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000002444 198.0
HFD2_k127_6566589_1 gluconolactonase activity - - - 0.000000000000000000000001099 121.0
HFD2_k127_656862_0 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 449.0
HFD2_k127_656862_1 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007882 314.0
HFD2_k127_6571191_0 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009644 394.0
HFD2_k127_6571191_1 Bacterial sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 324.0
HFD2_k127_6571191_2 FHA domain K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000005539 196.0
HFD2_k127_6571191_3 protein involved in exopolysaccharide biosynthesis - - - 0.000000000000000000000000000000000000000000002264 186.0
HFD2_k127_6571191_4 Polysaccharide biosynthesis/export protein K01991 - - 0.000000000000000000000000000000000000000003043 162.0
HFD2_k127_6571191_5 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.00000000000000000000377 101.0
HFD2_k127_6571191_6 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000000000000000006928 96.0
HFD2_k127_6571191_7 xylanase chitin deacetylase - - - 0.00000000000000000001176 104.0
HFD2_k127_6575058_0 ABC transporter transmembrane region K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 308.0
HFD2_k127_6575058_1 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K03594,K03921,K07052 - 1.14.19.11,1.14.19.2,1.14.19.26,1.16.3.1 0.0000000000000000000000000000000000000000000000004277 186.0
HFD2_k127_6575058_2 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000009934 124.0
HFD2_k127_6581258_0 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 293.0
HFD2_k127_6592681_0 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 383.0
HFD2_k127_6592681_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 343.0
HFD2_k127_6592681_2 Protein of unknown function (DUF1573) - - - 0.0000000003483 73.0
HFD2_k127_6592681_3 Worm-specific repeat type 1 - GO:0002009,GO:0002165,GO:0003674,GO:0005198,GO:0005201,GO:0005575,GO:0005576,GO:0007275,GO:0007399,GO:0007424,GO:0007444,GO:0007472,GO:0007475,GO:0007476,GO:0007552,GO:0007560,GO:0007591,GO:0008037,GO:0008038,GO:0008039,GO:0008150,GO:0008362,GO:0008587,GO:0009653,GO:0009791,GO:0009886,GO:0009887,GO:0009888,GO:0009987,GO:0022008,GO:0022404,GO:0030154,GO:0030182,GO:0031012,GO:0032501,GO:0032502,GO:0035107,GO:0035114,GO:0035120,GO:0035220,GO:0035239,GO:0035295,GO:0040003,GO:0040005,GO:0042303,GO:0042335,GO:0044421,GO:0044719,GO:0048468,GO:0048513,GO:0048563,GO:0048569,GO:0048666,GO:0048699,GO:0048707,GO:0048729,GO:0048731,GO:0048736,GO:0048737,GO:0048856,GO:0048869,GO:0060429,GO:0060541,GO:0060562,GO:0065007,GO:0065008,GO:0090066 - 0.00003453 55.0
HFD2_k127_6601268_0 Thiolase, C-terminal domain K00626,K07508 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 518.0
HFD2_k127_6601268_1 Histidine kinase - - - 0.00000000000000000003411 105.0
HFD2_k127_6601268_2 Transcription factor RfeF - - - 0.000002652 56.0
HFD2_k127_660649_0 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000179 245.0
HFD2_k127_660649_1 phospholipase C K01114 - 3.1.4.3 0.0000000000000000000000004889 119.0
HFD2_k127_6607332_0 Protein kinase domain K12132 - 2.7.11.1 0.00000000002526 72.0
HFD2_k127_6607332_2 - - - - 0.0000001656 58.0
HFD2_k127_6607332_3 WD domain, G-beta repeat - - - 0.00000265 60.0
HFD2_k127_6607412_0 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000001998 233.0
HFD2_k127_6607412_1 involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0008780,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.129 0.000000000000000000000000000000000000000000000001364 184.0
HFD2_k127_6607412_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000002404 154.0
HFD2_k127_6607412_3 PilZ domain - - - 0.0000000000000006043 85.0
HFD2_k127_661095_0 Pilus formation protein N terminal region K02280 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 420.0
HFD2_k127_661095_1 Type II secretion system (T2SS), protein F K12511 - - 0.00000000000000000000000000000000000000000000000000000000000000000003167 245.0
HFD2_k127_661095_2 Type II secretion system (T2SS), protein F K12510 - - 0.00000000000000000000000000000000000000000000004571 190.0
HFD2_k127_661095_4 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.0004185 44.0
HFD2_k127_6613312_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008293 452.0
HFD2_k127_6613312_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002035 284.0
HFD2_k127_6613312_2 Acyltransferase family - - - 0.000000000000000000000000000000000000000000003861 175.0
HFD2_k127_6621013_0 Belongs to the arginase family K01480 - 3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003825 537.0
HFD2_k127_6621013_1 B domain of TMEM189, localisation domain K20656 - - 0.000000000000000000000000000000000000000000000000000000000000000000104 248.0
HFD2_k127_6621013_2 COG1125 ABC-type proline glycine betaine transport systems ATPase components K05847 - - 0.00000000000000000000000000000000000000000607 160.0
HFD2_k127_6622940_2 transport - - - 0.000001647 56.0
HFD2_k127_6623880_0 Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 326.0
HFD2_k127_6623880_1 Domain of unknown function (DUF3943) - - - 0.0000000000000000000000000000000000000000000000000000000004721 208.0
HFD2_k127_6632526_0 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000002395 210.0
HFD2_k127_6632526_1 Helix-hairpin-helix motif K02237 - - 0.000000000000094 74.0
HFD2_k127_6632526_2 Peptidase_C39 like family - - - 0.000000002898 65.0
HFD2_k127_6636651_0 Polysaccharide deacetylase K22278 - 3.5.1.104 0.00000000000000000000000000000001996 140.0
HFD2_k127_6636651_1 deoxyhypusine monooxygenase activity - - - 0.0000000007808 64.0
HFD2_k127_6663702_0 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000008192 166.0
HFD2_k127_6663702_2 TPM domain K06872 - - 0.000000000000000000000000005368 121.0
HFD2_k127_6665929_0 Belongs to the aldehyde dehydrogenase family - - - 6.126e-222 696.0
HFD2_k127_6676132_0 Cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 355.0
HFD2_k127_6676132_1 Methyltransferase domain - - - 0.000000000000000000000000000000000000000007428 163.0
HFD2_k127_6676132_2 Universal stress protein - - - 0.000000000000001732 88.0
HFD2_k127_6676132_3 LysR substrate binding domain - - - 0.000000007847 58.0
HFD2_k127_6676132_4 AMP binding - - - 0.0000001867 63.0
HFD2_k127_6676132_5 Lipase family - - - 0.000009288 53.0
HFD2_k127_668019_0 Alpha-amylase domain K05343 - 3.2.1.1,5.4.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004245 400.0
HFD2_k127_6685644_0 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 466.0
HFD2_k127_6685644_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009483 415.0
HFD2_k127_6685644_2 Pyruvate dehydrogenase K00162 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 349.0
HFD2_k127_668847_0 PAP2 superfamily - - - 0.0000000000000000000000000000000000000000000000000002573 197.0
HFD2_k127_668847_1 Domain of unknown function (DUF3943) - - - 0.0000000000000000000000000001746 127.0
HFD2_k127_668847_2 Belongs to the ompA family K03640 - - 0.00000000000000000000001434 111.0
HFD2_k127_6689575_0 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 378.0
HFD2_k127_6689575_1 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 353.0
HFD2_k127_6697391_0 Alcohol dehydrogenase GroES-like domain K00008,K00148 - 1.1.1.14,1.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004198 424.0
HFD2_k127_6697391_1 Protein of unknown function (DUF3570) - - - 0.000000000000000001286 100.0
HFD2_k127_6697391_2 Glutathione peroxidase - - - 0.000000000000000007567 91.0
HFD2_k127_6697391_3 Domain of unknown function (DUF4266) - - - 0.000695 46.0
HFD2_k127_6698314_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003925 373.0
HFD2_k127_6698314_1 Belongs to the pyruvate kinase family K00873 GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000003637 267.0
HFD2_k127_6698314_2 - - - - 0.00000000000000000001377 101.0
HFD2_k127_6698314_3 Stage II sporulation protein E K07315 - 3.1.3.3 0.000000000000000004773 98.0
HFD2_k127_6712288_0 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 9.339e-244 773.0
HFD2_k127_6712288_1 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004783 313.0
HFD2_k127_6712288_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000004475 94.0
HFD2_k127_6712288_3 response regulator, receiver - - - 0.0000924 48.0
HFD2_k127_6715705_0 peptide catabolic process - - - 0.00000000008733 74.0
HFD2_k127_6720419_0 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 571.0
HFD2_k127_6720419_1 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004891 464.0
HFD2_k127_6720419_2 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000004136 123.0
HFD2_k127_6722405_0 - - - - 0.0000000000000000000003207 104.0
HFD2_k127_6722405_1 - - - - 0.000000000000000000006283 96.0
HFD2_k127_6722405_3 phosphatase K20074 - 3.1.3.16 0.0001325 51.0
HFD2_k127_6723567_0 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006692 445.0
HFD2_k127_6723567_1 NAD(P)H quinone oxidoreductase, PIG3 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 308.0
HFD2_k127_6723567_2 Ring hydroxylating alpha subunit (catalytic domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000003645 250.0
HFD2_k127_6723567_3 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000005194 193.0
HFD2_k127_6723567_4 metal cluster binding - - - 0.000000000000000000000000000000000000000000000001905 183.0
HFD2_k127_6723567_7 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000293 53.0
HFD2_k127_672964_0 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 390.0
HFD2_k127_672964_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000005234 147.0
HFD2_k127_672964_2 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000003316 67.0
HFD2_k127_672964_3 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.000000001766 68.0
HFD2_k127_6729963_0 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 402.0
HFD2_k127_6729963_1 Tetratricopeptide repeat - - - 0.000000002727 68.0
HFD2_k127_6733366_0 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K11779,K11784,K18285 - 1.21.98.1,2.5.1.120,2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 409.0
HFD2_k127_6733366_1 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.00000000000000000000000000000000000000000000000000006075 207.0
HFD2_k127_6733366_2 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000002151 143.0
HFD2_k127_6735933_0 thiol oxidoreductase - - - 0.000000000000000000000000000000000000002984 159.0
HFD2_k127_6735933_1 Phosphoesterase family K01114 - 3.1.4.3 0.000000000000000000005139 109.0
HFD2_k127_6741372_0 - - - - 0.0000000000000000000000000000000000000000000000000001046 209.0
HFD2_k127_6741372_1 alpha beta K06889 - - 0.0000000000000000000000000000000000000000009522 168.0
HFD2_k127_6741372_2 chlorophyll binding K21218 - - 0.000000000000000000000000000000000009531 142.0
HFD2_k127_6741372_3 Universal stress protein - - - 0.000000000000000000000000000009961 128.0
HFD2_k127_6741372_4 helix_turn_helix, mercury resistance - - - 0.0000000000000000000001307 104.0
HFD2_k127_6741372_5 Domain of unknown function (DUF2383) - - - 0.000000000000000000003181 99.0
HFD2_k127_6741372_6 COG4635 Flavodoxin K00230 - 1.3.5.3 0.000000000000009318 83.0
HFD2_k127_6741372_7 - - - - 0.000000006336 59.0
HFD2_k127_6741620_0 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000000003222 79.0
HFD2_k127_6741620_2 Phosphate-selective porin O and P K07221 - - 0.0000001202 64.0
HFD2_k127_6741620_3 alpha-L-arabinofuranosidase - - - 0.000001919 51.0
HFD2_k127_6746608_0 Peptidase family M1 domain K01256 - 3.4.11.2 8.002e-301 943.0
HFD2_k127_6755747_1 TIGRFAM clan AA aspartic protease, TIGR02281 family K06985 - - 0.00005556 55.0
HFD2_k127_6757499_0 AcrB/AcrD/AcrF family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005471 622.0
HFD2_k127_6757499_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000002698 74.0
HFD2_k127_676839_0 Flagellar basal body rod K02396,K03333 - 1.1.3.6 0.000000000000000000000000000000000000000000000000001762 198.0
HFD2_k127_676839_1 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000001878 148.0
HFD2_k127_6769210_0 iron ion binding - - - 0.0000000000000000000000000000000000000000000000000000000000003131 220.0
HFD2_k127_6769210_1 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000003496 201.0
HFD2_k127_6769210_2 AAA ATPase domain - - - 0.000000000000002503 78.0
HFD2_k127_6773189_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 427.0
HFD2_k127_6773189_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000001923 161.0
HFD2_k127_6776391_0 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000006025 223.0
HFD2_k127_6776391_1 Belongs to the precorrin methyltransferase family K01719,K01749,K02302,K02303,K13542 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.76,2.1.1.107,2.5.1.61,4.2.1.75,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000001519 220.0
HFD2_k127_6776391_2 ABC transporter K02049 - - 0.000000002678 61.0
HFD2_k127_6776568_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 495.0
HFD2_k127_6776568_1 PFAM NAD dependent epimerase dehydratase family K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001035 257.0
HFD2_k127_6776568_3 protein kinase activity - - - 0.0000000000000000000000001193 121.0
HFD2_k127_6778538_0 PFAM Glycoside hydrolase 15-related - - - 0.00000000000000000000000000000000000000000000000001157 198.0
HFD2_k127_6793835_0 positive regulation of MDA-5 signaling pathway K16726 GO:0000785,GO:0001568,GO:0001654,GO:0001745,GO:0001751,GO:0001754,GO:0001817,GO:0001819,GO:0001944,GO:0001955,GO:0002376,GO:0002682,GO:0002684,GO:0002697,GO:0002699,GO:0002831,GO:0002833,GO:0003674,GO:0003682,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005694,GO:0005737,GO:0006275,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0006996,GO:0007005,GO:0007010,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007275,GO:0007346,GO:0007399,GO:0007423,GO:0007492,GO:0008150,GO:0009605,GO:0009607,GO:0009617,GO:0009653,GO:0009887,GO:0009888,GO:0009889,GO:0009892,GO:0009894,GO:0009895,GO:0009966,GO:0009967,GO:0009987,GO:0010506,GO:0010507,GO:0010556,GO:0010564,GO:0010639,GO:0010646,GO:0010647,GO:0010821,GO:0010823,GO:0010927,GO:0010941,GO:0012505,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019730,GO:0019899,GO:0019900,GO:0019901,GO:0021700,GO:0022008,GO:0022607,GO:0023051,GO:0023052,GO:0023056,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030154,GO:0030182,GO:0030239,GO:0031032,GO:0031090,GO:0031323,GO:0031324,GO:0031326,GO:0031329,GO:0031330,GO:0031347,GO:0031349,GO:0031430,GO:0031672,GO:0031674,GO:0031965,GO:0031967,GO:0031975,GO:0032101,GO:0032103,GO:0032501,GO:0032502,GO:0032989,GO:0033043,GO:0039531,GO:0039533,GO:0039535,GO:0040011,GO:0042692,GO:0042742,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043122,GO:0043123,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043292,GO:0043900,GO:0043902,GO:0044085,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044449,GO:0044464,GO:0045087,GO:0045088,GO:0045089,GO:0045214,GO:0045595,GO:0045596,GO:0045787,GO:0045931,GO:0046530,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048592,GO:0048646,GO:0048699,GO:0048731,GO:0048749,GO:0048856,GO:0048869,GO:0050688,GO:0050776,GO:0050778,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051052,GO:0051093,GO:0051128,GO:0051129,GO:0051146,GO:0051147,GO:0051148,GO:0051150,GO:0051151,GO:0051171,GO:0051239,GO:0051240,GO:0051704,GO:0051707,GO:0051716,GO:0051726,GO:0055001,GO:0055002,GO:0060255,GO:0060361,GO:0060548,GO:0061061,GO:0065007,GO:0070925,GO:0071695,GO:0071840,GO:0072358,GO:0072359,GO:0080090,GO:0080134,GO:0090068,GO:0090596,GO:0097435,GO:0098542,GO:0099080,GO:0099081,GO:0099512,GO:1900087,GO:1900245,GO:1900246,GO:1901987,GO:1901989,GO:1901990,GO:1901992,GO:1902531,GO:1902533,GO:1902806,GO:1902808,GO:1903146,GO:1903147,GO:2000045,GO:2000112 - 0.000000005931 67.0
HFD2_k127_6820391_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 347.0
HFD2_k127_6820391_1 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000003436 272.0
HFD2_k127_6820391_2 PQQ-like domain - - - 0.0000000152 66.0
HFD2_k127_6832698_0 RecG wedge domain K03655 GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004698 336.0
HFD2_k127_6832698_1 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000007751 212.0
HFD2_k127_6838098_0 amine dehydrogenase activity - - - 0.00000000000003306 83.0
HFD2_k127_6838578_0 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000121 217.0
HFD2_k127_6838578_1 Esterase PHB depolymerase K03932 - - 0.0000000000001503 82.0
HFD2_k127_6838578_2 Poly3-Hydroxybutyrate Depolymerase K03932 - - 0.00000005752 61.0
HFD2_k127_6838773_0 AcrB/AcrD/AcrF family K07787,K15726 - - 1.032e-304 947.0
HFD2_k127_6838773_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.00000000000000000000000000000000000000000000000000000000005421 210.0
HFD2_k127_6839760_0 PFAM Glycosyl transferase family 2 K10012 - 2.4.2.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 374.0
HFD2_k127_6839760_1 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 309.0
HFD2_k127_6840057_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000002153 229.0
HFD2_k127_6840057_1 Pyridoxamine 5'-phosphate oxidase K09979 - - 0.000000000000000000000005598 108.0
HFD2_k127_6840057_2 - - - - 0.0009174 44.0
HFD2_k127_6841146_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000709 464.0
HFD2_k127_6841146_1 Biotin-lipoyl like K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007502 437.0
HFD2_k127_6841146_2 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005631 413.0
HFD2_k127_6841146_3 (ABC) transporter K01990 - - 0.000000000000000000000000000000000000000000000000000003707 194.0
HFD2_k127_6849991_0 Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000000000000000007574 229.0
HFD2_k127_6849991_1 - - - - 0.00000000000002068 81.0
HFD2_k127_6860903_0 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005326 314.0
HFD2_k127_6860903_1 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000000003097 131.0
HFD2_k127_6860903_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000008105 67.0
HFD2_k127_6863452_0 peptidase activity - - - 0.00000004473 61.0
HFD2_k127_6866054_0 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005318 582.0
HFD2_k127_6866054_1 Intracellular protease, PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000000000003454 249.0
HFD2_k127_6866054_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000003941 122.0
HFD2_k127_6868917_0 Helicase K17675 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 565.0
HFD2_k127_6868917_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 429.0
HFD2_k127_6875980_0 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 373.0
HFD2_k127_6875980_1 Pfam:Pyridox_oxidase K07006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 293.0
HFD2_k127_6875980_2 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001893 229.0
HFD2_k127_6875980_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.0000000000000000000000000002084 124.0
HFD2_k127_6878271_0 Elongator protein 3, MiaB family, Radical SAM K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 544.0
HFD2_k127_6878271_1 Belongs to the MEMO1 family K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005101 254.0
HFD2_k127_6878271_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000002585 250.0
HFD2_k127_6878271_3 Beta-lactamase K17836 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000000004464 211.0
HFD2_k127_6878271_4 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000001993 68.0
HFD2_k127_6878932_0 transcriptional regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000001476 134.0
HFD2_k127_6878932_1 PFAM TonB-dependent Receptor Plug - - - 0.000000000000000001448 92.0
HFD2_k127_6878932_2 Beta-L-arabinofuranosidase, GH127 - - - 0.0000001906 63.0
HFD2_k127_6879875_0 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol - - - 0.0000000000000000000000000000000000000000000002327 181.0
HFD2_k127_6879875_1 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000000000000000000000000004132 171.0
HFD2_k127_6881211_0 - - - - 0.00000002936 66.0
HFD2_k127_6882861_0 Diacylglycerol kinase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 338.0
HFD2_k127_6882861_1 Belongs to the GcvT family K06980 - - 0.0000000000000000000000000000000000000000000000000000009154 205.0
HFD2_k127_6884159_0 Putative modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006027 571.0
HFD2_k127_6884159_1 Putative modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000437 317.0
HFD2_k127_6884548_0 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005501 307.0
HFD2_k127_6884548_1 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000137 249.0
HFD2_k127_6884548_2 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000000008566 221.0
HFD2_k127_6884548_5 FAD linked oxidases, C-terminal domain K00102,K00104 - 1.1.2.4,1.1.3.15 0.000000002441 58.0
HFD2_k127_6888591_0 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005642 330.0
HFD2_k127_6888591_1 Glycosyl hydrolase family 65, N-terminal domain - - - 0.000000000001045 81.0
HFD2_k127_6888591_2 transferase activity, transferring glycosyl groups - - - 0.0006267 51.0
HFD2_k127_6889241_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000009215 255.0
HFD2_k127_6889241_1 Belongs to the peptidase S1B family - - - 0.000000000000000000000000000000000000000000000000000000000000001922 229.0
HFD2_k127_6889241_2 Dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000002438 163.0
HFD2_k127_6890820_0 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000934 332.0
HFD2_k127_6897207_0 Arginyl tRNA synthetase N terminal dom K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004558 598.0
HFD2_k127_6897207_1 Sporulation related domain - - - 0.0000000000000004544 86.0
HFD2_k127_6902002_0 - - - - 0.00000000000000000000000000000000000000000000002499 186.0
HFD2_k127_6902002_1 - - - - 0.0000000000005382 79.0
HFD2_k127_6902002_2 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000008204 57.0
HFD2_k127_6905402_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 373.0
HFD2_k127_6907597_0 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000002878 232.0
HFD2_k127_6907597_1 HAMP domain - - - 0.0000008912 61.0
HFD2_k127_6911197_0 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.00000000000000000003022 92.0
HFD2_k127_6911197_1 SH3 type 3 domain protein K01447 - 3.5.1.28 0.000003435 58.0
HFD2_k127_6913742_0 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 439.0
HFD2_k127_6928947_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0000000000000000000000002482 108.0
HFD2_k127_6928947_1 Belongs to the ompA family K20276 - - 0.00000001581 67.0
HFD2_k127_6929531_0 Sel1-like repeats. K07126 - - 0.000000000000000000000000000000000000007442 155.0
HFD2_k127_6929531_1 - - - - 0.0000000000000000000000001133 111.0
HFD2_k127_6929531_2 Domain of unknown function (DUF4833) - - - 0.0000000000000000007252 97.0
HFD2_k127_6934245_0 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005225 457.0
HFD2_k127_6934245_1 Polysaccharide deacetylase K22278 - 3.5.1.104 0.00000000000000000000000000000002091 141.0
HFD2_k127_6934245_2 Periplasmic protein TonB links inner and outer membranes - - - 0.000000006512 61.0
HFD2_k127_6936383_0 Sterol desaturase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009515 254.0
HFD2_k127_6936383_1 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000001639 179.0
HFD2_k127_6936383_2 ABC transporter K01990 - - 0.00000000000000000000000000000000000000004729 163.0
HFD2_k127_6936383_3 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000116 118.0
HFD2_k127_6936383_4 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000783 93.0
HFD2_k127_6936383_5 ABC-type multidrug transport system, permease component K01992 - - 0.0000000000001445 83.0
HFD2_k127_6936913_0 PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000004264 216.0
HFD2_k127_6940052_0 DNA-binding response regulator K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 320.0
HFD2_k127_6940052_1 Family membership K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000005227 252.0
HFD2_k127_6940052_2 - - - - 0.00000000000000000000009771 109.0
HFD2_k127_6948966_0 Iron-containing alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 469.0
HFD2_k127_6948966_1 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000000000000000006454 163.0
HFD2_k127_6952847_0 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000519 332.0
HFD2_k127_6952847_1 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 290.0
HFD2_k127_6952847_2 Domain of unknown function (DUF4350) - - - 0.000000002927 69.0
HFD2_k127_6956295_0 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000000000000003478 134.0
HFD2_k127_6956295_1 - - - - 0.0008862 50.0
HFD2_k127_6957234_0 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003491 303.0
HFD2_k127_6957234_1 response to heat K07090 - - 0.000000000000000000000000000000000000000000000003676 181.0
HFD2_k127_6959865_0 Cellulose biosynthesis protein BcsQ K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006787 436.0
HFD2_k127_6959865_1 - - - - 0.0000000000000000000000000002571 117.0
HFD2_k127_6962294_0 Endonuclease Exonuclease Phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000001402 227.0
HFD2_k127_6962796_0 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002509 256.0
HFD2_k127_6965078_0 - - - - 0.00000000000000000000000000000000008439 138.0
HFD2_k127_6965078_1 DnaJ molecular chaperone homology domain - - - 0.0000000000000000000000000000000005997 141.0
HFD2_k127_6970453_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003508 490.0
HFD2_k127_6970453_1 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000000000000000000000000000002165 223.0
HFD2_k127_6970453_2 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000165 164.0
HFD2_k127_6983077_0 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 309.0
HFD2_k127_6983077_1 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001402 255.0
HFD2_k127_6983077_2 protein kinase activity - - - 0.0000000000000000001446 92.0
HFD2_k127_6984066_0 chloride channel K03281 - - 0.0000000000000000000000000000000000000000000000000000000000004632 232.0
HFD2_k127_6984066_1 aspartate-semialdehyde dehydrogenase activity K00133 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004073,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009088,GO:0009090,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.11 0.00000000000000000000000000000000000000000000000000000003926 201.0
HFD2_k127_6984066_2 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000002082 159.0
HFD2_k127_6984066_3 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000001696 152.0
HFD2_k127_6984066_4 Universal stress protein family - - - 0.00000000000000000000000000000000007439 138.0
HFD2_k127_6984066_5 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000005727 94.0
HFD2_k127_6984066_6 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.000000000001133 69.0
HFD2_k127_6990921_0 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004641 263.0
HFD2_k127_6990921_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000005873 239.0
HFD2_k127_6990921_2 PFAM Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000006658 179.0
HFD2_k127_6990921_3 Transcriptional regulatory protein, C terminal - - - 0.0000000000000001869 94.0
HFD2_k127_6990921_4 cellulose binding - - - 0.0003251 52.0
HFD2_k127_6991191_0 Flavin-binding monooxygenase-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 326.0
HFD2_k127_6992797_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000001196 252.0
HFD2_k127_6992797_1 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000869 152.0
HFD2_k127_6993212_0 Oxidoreductase NAD-binding domain K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000001189 253.0
HFD2_k127_6993212_1 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000309 247.0
HFD2_k127_6993212_2 - - - - 0.00000000000000000000000000000000002431 143.0
HFD2_k127_6993212_3 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000002788 70.0
HFD2_k127_6993212_4 - - - - 0.00005627 51.0
HFD2_k127_6997839_0 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003528 361.0
HFD2_k127_6997839_1 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000006536 202.0
HFD2_k127_6997839_2 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.0000000000000000000000000000000000000000000172 166.0
HFD2_k127_7003074_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes K02405 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000004276 149.0
HFD2_k127_7003074_1 flagellar K02404 - - 0.000000000000000000002009 101.0
HFD2_k127_7003074_2 Belongs to the flagella basal body rod proteins family K02391,K02392 - - 0.00000000000000001716 90.0
HFD2_k127_7003074_3 Belongs to the flagella basal body rod proteins family K02391,K02392 - - 0.000006057 49.0
HFD2_k127_7003074_4 Rod binding protein K02395 - - 0.0007542 50.0
HFD2_k127_7012225_0 Belongs to the glycosyl hydrolase 35 family K12308 - 3.2.1.23 0.0000000000000000000000000000000000000000000000000000003173 203.0
HFD2_k127_7014250_0 signal peptide peptidase SppA, 36K type K04773 - - 9.865e-199 648.0
HFD2_k127_701693_0 Activator of Hsp90 ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002462 243.0
HFD2_k127_701693_1 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000000000000000000006027 208.0
HFD2_k127_701693_2 Concanavalin A-like lectin/glucanases superfamily - - - 0.0000000000000002124 91.0
HFD2_k127_7025100_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004944 432.0
HFD2_k127_7026321_0 Phospholipase/Carboxylesterase - - - 0.00000000000000000000000014 123.0
HFD2_k127_7031314_0 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008297 269.0
HFD2_k127_7031314_1 protein trimerization - - - 0.000000000000000000000000001115 127.0
HFD2_k127_7040447_0 D-alanyl-D-alanine carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000008922 238.0
HFD2_k127_7040447_1 D-alanyl-D-alanine carboxypeptidase - - - 0.00000000000000000000000000000000000000000001592 169.0
HFD2_k127_7043456_0 Serine aminopeptidase, S33 K07019 - - 0.0000000000000000000000000000000004359 145.0
HFD2_k127_7043456_1 NUDIX hydrolase K03574 - 3.6.1.55 0.000000000000000000002078 95.0
HFD2_k127_7043456_2 phosphorylase K00688 - 2.4.1.1 0.000000000000000000003162 98.0
HFD2_k127_7047230_0 cytochrome p450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004927 398.0
HFD2_k127_7047230_1 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000002416 200.0
HFD2_k127_7048085_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008764 327.0
HFD2_k127_7048085_1 YARHG - - - 0.00000000000000000000000000000000000000000002825 173.0
HFD2_k127_7048422_0 Protein kinase domain K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 582.0
HFD2_k127_7048422_1 Forkhead associated domain K21405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005678 368.0
HFD2_k127_7048422_2 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 304.0
HFD2_k127_7054420_0 2Fe-2S iron-sulfur cluster binding domain K00302 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 317.0
HFD2_k127_7057953_0 DNA helicase K03656,K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 471.0
HFD2_k127_7060183_0 PFAM sigma-54 factor interaction domain-containing protein K07715 - - 0.0000000000000000000000000000000000000000000000000000000000000000001195 239.0
HFD2_k127_7065725_0 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 511.0
HFD2_k127_7065725_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 319.0
HFD2_k127_7065725_2 Nucleoside 2-deoxyribosyltransferase like - - - 0.0000000000000000000000000006184 119.0
HFD2_k127_7075025_0 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.000000002249 68.0
HFD2_k127_7078696_0 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007371 326.0
HFD2_k127_7078696_2 PFAM SMP-30 Gluconolaconase - - - 0.000002605 59.0
HFD2_k127_7086610_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 559.0
HFD2_k127_7087712_0 GMC oxidoreductase K00108 - 1.1.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 533.0
HFD2_k127_7087712_1 leucine-rich repeat-containing protein typical subtype K13730 - - 0.00000001275 66.0
HFD2_k127_7093441_1 helix_turn_helix, Lux Regulon - - - 0.00002531 53.0
HFD2_k127_7093441_2 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0001823 50.0
HFD2_k127_7093441_3 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K07684 - - 0.0003862 52.0
HFD2_k127_7103017_0 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006452 513.0
HFD2_k127_7103017_1 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 385.0
HFD2_k127_7103017_2 cellulase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000178 269.0
HFD2_k127_7103017_3 Aldo Keto reductase - - - 0.00000000000000000000000000000000000006976 147.0
HFD2_k127_7103017_4 PFAM GPR1 FUN34 yaaH family K07034 - - 0.0008114 50.0
HFD2_k127_71063_0 Belongs to the heme-copper respiratory oxidase family K15862 - 1.9.3.1 1.305e-256 815.0
HFD2_k127_71063_1 Cytochrome c K00406 - - 0.0000000000000000000000000000000000000000002464 165.0
HFD2_k127_71063_2 E1-E2 ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 0.0000000000000000000000000000000007399 137.0
HFD2_k127_71109_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000001846 212.0
HFD2_k127_7113632_2 Uncharacterized protein conserved in bacteria (DUF2330) - - - 0.0008796 52.0
HFD2_k127_7118808_0 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000003614 146.0
HFD2_k127_7118808_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000001437 103.0
HFD2_k127_7124865_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 3.118e-214 685.0
HFD2_k127_7124865_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000006027 183.0
HFD2_k127_7129851_0 penicillin-binding protein K03587 - 3.4.16.4 8.94e-244 768.0
HFD2_k127_7129851_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 357.0
HFD2_k127_7129851_2 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000004882 227.0
HFD2_k127_7129851_3 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.000000000000000000000000000000000000000005111 158.0
HFD2_k127_713138_0 PFAM glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001279 250.0
HFD2_k127_713138_1 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791,K13019 - 5.1.3.14,5.1.3.23 0.00000000000000000000000000000001255 131.0
HFD2_k127_713138_2 - - - - 0.0000000000000000000000000004158 129.0
HFD2_k127_7132290_0 SMART serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001904 290.0
HFD2_k127_7132290_1 Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7' - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004576 271.0
HFD2_k127_7132290_2 - - - - 0.0000009537 55.0
HFD2_k127_713369_0 COGs COG2148 Sugar transferase involved in lipopolysaccharide synthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 431.0
HFD2_k127_713369_1 SnoaL-like polyketide cyclase - - - 0.00000000000000000000003181 104.0
HFD2_k127_7134028_0 TatD family K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 351.0
HFD2_k127_7134028_2 Endonuclease Exonuclease Phosphatase K01179 - 3.2.1.4 0.000001165 58.0
HFD2_k127_7135702_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1014.0
HFD2_k127_7135702_1 conserved protein UCP033563 - - - 0.0000000008426 60.0
HFD2_k127_7141687_0 Carbon starvation protein K06200 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006846 594.0
HFD2_k127_714504_0 domain, Protein - - - 0.0000000000000000000000000000000000000002726 154.0
HFD2_k127_7145470_0 acetyltransferases and hydrolases with the alpha beta hydrolase fold K01046 - 3.1.1.3 0.00000000000000000000000000000000000000002892 163.0
HFD2_k127_7145470_1 Acid phosphatase homologues - - - 0.0003227 52.0
HFD2_k127_7158166_0 protein kinase activity K08884 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000001455 242.0
HFD2_k127_7158166_1 Rhodanese Homology Domain - - - 0.00000000000000000000000002324 115.0
HFD2_k127_7158661_0 Metal-dependent phosphohydrolase, HD region - - - 0.000000000000000001176 101.0
HFD2_k127_7158661_1 deoxyhypusine monooxygenase activity - - - 0.000001379 61.0
HFD2_k127_7159941_0 - - - - 0.0000000000000000000000000000000000000206 151.0
HFD2_k127_7159941_1 - - - - 0.000000000000000000000000004755 116.0
HFD2_k127_7166246_0 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005429 342.0
HFD2_k127_7166246_1 - - - - 0.00000000004857 75.0
HFD2_k127_7166687_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 606.0
HFD2_k127_7166687_1 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001199 281.0
HFD2_k127_7168460_0 stress-induced mitochondrial fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 452.0
HFD2_k127_7168460_1 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002616 312.0
HFD2_k127_7168460_2 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000007675 163.0
HFD2_k127_7171800_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 1.328e-216 682.0
HFD2_k127_7171800_1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.00000000000000000000000000000000002171 141.0
HFD2_k127_7171800_2 - - - - 0.00000000000000000000000000009443 126.0
HFD2_k127_7171800_3 Sigma 54 modulation protein / S30EA ribosomal protein K05808 - - 0.0000000000000000000000001104 109.0
HFD2_k127_7171800_4 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000009552 84.0
HFD2_k127_7180990_0 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 303.0
HFD2_k127_7182288_0 peptidyl-tyrosine sulfation - - - 0.0001836 53.0
HFD2_k127_7182401_0 PFAM binding-protein-dependent transport systems inner membrane component K02018 - - 0.0000000000000000000000000000000000000000000000000001113 196.0
HFD2_k127_7182401_1 Belongs to the ABC transporter superfamily K02017 - 3.6.3.29 0.000000000000000000000000000000000000000000000003483 183.0
HFD2_k127_7182401_2 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642,K21688 - - 0.000000000000000000000000000000000001313 151.0
HFD2_k127_7183900_0 Cytochrome b subunit of the bc complex K00412 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 418.0
HFD2_k127_7183900_1 Rieske [2Fe-2S] domain K02636 - 1.10.9.1 0.00000000000000000000000000000006195 132.0
HFD2_k127_7184315_0 ABC transporter, ATP-binding protein K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004708 396.0
HFD2_k127_7186845_0 FHA domain - - - 0.00000000000000000000000000000000003349 156.0
HFD2_k127_7186845_1 NUDIX domain - - - 0.0000000000000000009633 89.0
HFD2_k127_7188348_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002355 295.0
HFD2_k127_7188348_1 peptidase inhibitor activity - - - 0.00000000000000000005475 92.0
HFD2_k127_7190126_0 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840,K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 492.0
HFD2_k127_7190126_1 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 321.0
HFD2_k127_7190126_2 Domain of unknown function (DUF4132) - - - 0.000000000000000002441 100.0
HFD2_k127_7190126_3 - - - - 0.000000000000003165 84.0
HFD2_k127_7190126_4 - - - - 0.00000000000005384 86.0
HFD2_k127_7190126_5 Response regulator receiver domain - - - 0.00000000000138 74.0
HFD2_k127_7197054_0 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000000000005178 190.0
HFD2_k127_7197054_1 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.0002202 53.0
HFD2_k127_7205563_0 - - - - 0.000000000000000000003311 105.0
HFD2_k127_7205563_2 Belongs to the UPF0312 family - - - 0.0002028 49.0
HFD2_k127_7210727_0 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001011 286.0
HFD2_k127_7210974_0 - - - - 0.000000000000000000005376 101.0
HFD2_k127_7210974_1 protein trimerization - - - 0.00000001876 67.0
HFD2_k127_7213544_0 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005475 342.0
HFD2_k127_7213544_1 glucose sorbosone - - - 0.0000000000000000000000003998 109.0
HFD2_k127_722052_0 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000487 458.0
HFD2_k127_722052_1 Oxidoreductase family, NAD-binding Rossmann fold K00968 - 2.7.7.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003077 394.0
HFD2_k127_7222406_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K09251 - 2.6.1.82 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007251 510.0
HFD2_k127_7222406_1 Belongs to the peptidase S8 family K13276 - - 0.0000000003835 72.0
HFD2_k127_7231577_0 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007484 266.0
HFD2_k127_7231577_1 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.0000000000000000000000000000003187 135.0
HFD2_k127_7231577_2 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000001014 72.0
HFD2_k127_7231577_4 Transcription factor zinc-finger - - - 0.0000743 53.0
HFD2_k127_7238427_0 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 393.0
HFD2_k127_7238427_1 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000000000401 151.0
HFD2_k127_7239609_0 response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002261 244.0
HFD2_k127_7239609_1 - - - - 0.0000000000000004718 89.0
HFD2_k127_7239609_2 - - - - 0.00000003718 65.0
HFD2_k127_7258339_0 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 365.0
HFD2_k127_7258339_1 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000004171 228.0
HFD2_k127_7258339_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000002065 182.0
HFD2_k127_7258339_5 Helix-turn-helix XRE-family like proteins - - - 0.000002543 54.0
HFD2_k127_7291990_0 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000005968 274.0
HFD2_k127_7297685_0 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000002418 195.0
HFD2_k127_7297685_1 SnoaL-like polyketide cyclase - - - 0.000000000000000000000000000000000003255 142.0
HFD2_k127_7297685_2 mannose binding K17513,K22244 - - 0.000000000000000000000000000001107 130.0
HFD2_k127_7297685_3 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000002192 113.0
HFD2_k127_7302973_0 Flotillin K07192 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 392.0
HFD2_k127_7302973_1 heat shock protein binding - - - 0.00000000569 67.0
HFD2_k127_7302973_2 DSBA-like thioredoxin domain - - - 0.0005102 43.0
HFD2_k127_7302973_3 Membrane protein implicated in regulation of membrane protease activity - - - 0.0006978 50.0
HFD2_k127_7303008_0 Aldehyde dehydrogenase family K02618,K15514 - 1.2.1.77,1.2.1.91,3.3.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004578 610.0
HFD2_k127_7303008_1 High confidence in function and specificity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000439 365.0
HFD2_k127_7303008_2 DSBA-like thioredoxin domain - - - 0.0005102 43.0
HFD2_k127_7305238_0 PFAM SpoVR family protein K06415 - - 5.632e-286 905.0
HFD2_k127_7306173_0 PFAM Carboxylyase-related protein K03182 - 4.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003874 494.0
HFD2_k127_7306173_1 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.000007168 48.0
HFD2_k127_7311218_0 Aminotransferase K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003633 516.0
HFD2_k127_7313647_0 serine-type endopeptidase activity K01346 - 3.4.21.71 0.00000000000716 72.0
HFD2_k127_7313647_1 PFAM peptidase S1 and S6, chymotrypsin Hap - - - 0.00001046 56.0
HFD2_k127_7317928_0 Polysaccharide deacetylase K22278 - 3.5.1.104 0.0000000000000000000005701 108.0
HFD2_k127_7317928_2 Belongs to the glycosyltransferase 26 family K05946 - 2.4.1.187 0.000000000000003614 83.0
HFD2_k127_7319921_0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00241 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004169 253.0
HFD2_k127_7319921_1 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000289 124.0
HFD2_k127_7319921_2 Beta-L-arabinofuranosidase, GH127 - - - 0.000000000000006637 87.0
HFD2_k127_7336809_1 nuclear chromosome segregation - - - 0.0000000000001203 76.0
HFD2_k127_7339058_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008464 563.0
HFD2_k127_7339058_1 NYN domain - - - 0.0000000000000000000007789 98.0
HFD2_k127_7339058_2 Glucose-6-phosphate dehydrogenase subunit - - - 0.00000000000000000000102 109.0
HFD2_k127_7339593_0 COG0659 Sulfate permease and related transporters (MFS superfamily) K01673,K03321 - 4.2.1.1 3.528e-224 711.0
HFD2_k127_7346112_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000008869 233.0
HFD2_k127_7346112_2 Kazal type serine protease inhibitors - - - 0.0000000000000000002174 96.0
HFD2_k127_7346112_3 isomerase activity - - - 0.0009326 51.0
HFD2_k127_7357497_0 Belongs to the glycosyl hydrolase 43 family K06113 - 3.2.1.99 0.000000000000000000000000000000000000000000000000000000000000000000007865 239.0
HFD2_k127_7357497_1 protein kinase activity - - - 0.000000000000000000000000000000000000000001028 174.0
HFD2_k127_7357497_2 Short repeat of unknown function (DUF308) - - - 0.00000000000000000000000000597 118.0
HFD2_k127_7357497_3 Universal stress protein - - - 0.000000000000000000000004374 108.0
HFD2_k127_7357497_4 - - - - 0.0005096 49.0
HFD2_k127_7363153_0 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.00000000000000000000000000000000000006236 160.0
HFD2_k127_736456_0 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000003589 264.0
HFD2_k127_736456_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000007811 165.0
HFD2_k127_736456_2 peptidyl-tyrosine sulfation - - - 0.0002294 44.0
HFD2_k127_7366046_0 Anti-sigma-K factor rskA - - - 0.000000000000000000000000000000000007099 147.0
HFD2_k127_7374765_0 - K21449 - - 0.0000000000000000000000000000000000000000000000000000000000003831 227.0
HFD2_k127_7374765_1 Belongs to the glycosyl hydrolase 13 family K01176 - 3.2.1.1 0.000000000000000000001272 108.0
HFD2_k127_7380392_0 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 366.0
HFD2_k127_7380392_1 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 K02806 - - 0.0000000000000000000000057 108.0
HFD2_k127_7381944_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.000003144 59.0
HFD2_k127_7381944_1 outer membrane efflux protein K15725 - - 0.00001092 58.0
HFD2_k127_7381944_2 exo-alpha-(2->6)-sialidase activity - - - 0.0008427 51.0
HFD2_k127_7383681_0 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 490.0
HFD2_k127_7383681_1 repeat protein - - - 0.000000000001279 74.0
HFD2_k127_7383681_2 Planctomycete cytochrome C - - - 0.00001535 53.0
HFD2_k127_7400787_0 Enoyl-(Acyl carrier protein) reductase K13775 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005865 428.0
HFD2_k127_7400787_1 Methyltransferase domain - - - 0.0000000000000001223 86.0
HFD2_k127_7400787_2 Lamin Tail Domain - - - 0.00005825 53.0
HFD2_k127_7403658_0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) K06169 - - 0.0000000000000000000000000000000000000000008362 164.0
HFD2_k127_7403658_1 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000002674 131.0
HFD2_k127_7408611_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 6.399e-268 836.0
HFD2_k127_7408611_1 PFAM Cys Met metabolism K01739,K01761 - 2.5.1.48,4.4.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 330.0
HFD2_k127_7408611_2 EamA-like transporter family - - - 0.00000000000000000000000000000000000002191 155.0
HFD2_k127_7410745_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 326.0
HFD2_k127_7410745_1 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000000000000000000008044 216.0
HFD2_k127_7410745_2 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000000000000000005877 179.0
HFD2_k127_7410745_3 Endonuclease containing a URI domain K07461 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 0.000000000000000000198 100.0
HFD2_k127_7415874_0 MotA/TolQ/ExbB proton channel family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003126 340.0
HFD2_k127_7415874_1 Biopolymer transport protein ExbD/TolR - - - 0.00000000000000000000000000000000000000000000000000000000000000000004314 235.0
HFD2_k127_7415874_2 Biopolymer transport protein ExbD/TolR - - - 0.000000000000000000000000000000000000000000000000000006149 195.0
HFD2_k127_741628_0 Domain of unknown function (DUF4091) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 527.0
HFD2_k127_741628_1 COG0332 3-oxoacyl- acyl-carrier-protein synthase III K16872 - 2.3.1.207 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009511 486.0
HFD2_k127_7422495_0 Large extracellular alpha-helical protein K06894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 439.0
HFD2_k127_7422495_1 Beta propeller domain - - - 0.0000000000000000000000000000000000000000000000000000000009089 211.0
HFD2_k127_7436210_0 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000004296 244.0
HFD2_k127_7436210_1 enterobactin catabolic process K07214 - - 0.0000000000000000000000000000000000000000000000000000001385 210.0
HFD2_k127_7436210_3 OmpA family K02557 - - 0.0000000000000000005572 90.0
HFD2_k127_7440057_0 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000001206 177.0
HFD2_k127_7440057_1 PFAM Protein kinase domain K08309 - - 0.000000000000000000000000003801 121.0
HFD2_k127_7440956_0 SMART helicase c2 K03722 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006457 557.0
HFD2_k127_7440956_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008107 448.0
HFD2_k127_744508_0 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004001 306.0
HFD2_k127_7446079_0 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 310.0
HFD2_k127_7446079_1 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003591 278.0
HFD2_k127_7446079_3 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.0000000000000000002269 95.0
HFD2_k127_7446301_0 Angiotensin-converting enzyme K01283 - 3.4.15.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 332.0
HFD2_k127_7446301_1 General secretion pathway protein C K02452 - - 0.000000000000000000000000000000000000000000000000000004519 201.0
HFD2_k127_7446301_2 Aminotransferase class I and II K14267 - 2.6.1.17 0.000000000000000000000000000000000000000000002456 175.0
HFD2_k127_7451007_0 stress-induced mitochondrial fusion - - - 5.791e-217 685.0
HFD2_k127_7451007_1 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.00000000000000000000000000000000000000000001958 175.0
HFD2_k127_7451007_2 Fibrobacter succinogenes major domain (Fib_succ_major) - - - 0.00000000000000000000003164 108.0
HFD2_k127_7453284_0 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000009142 160.0
HFD2_k127_7457465_0 Belongs to the FPP GGPP synthase family K00805,K02523 - 2.5.1.30,2.5.1.90 0.000000000000000000000000000000000000000000000000000000000249 216.0
HFD2_k127_7457465_2 Belongs to the GbsR family - - - 0.00000000003495 65.0
HFD2_k127_7457986_0 - - - - 0.000000000000000000000000000002726 125.0
HFD2_k127_7466544_0 lipid kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000007176 248.0
HFD2_k127_7474774_0 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003453 591.0
HFD2_k127_7480782_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006921 331.0
HFD2_k127_7480782_1 Glycosyl hydrolases family 31 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008355 305.0
HFD2_k127_7482027_0 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000914 353.0
HFD2_k127_7482027_1 Spermidine synthase K00797 - 2.5.1.16 0.00000000000000000000000000000214 134.0
HFD2_k127_7482027_2 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000005457 127.0
HFD2_k127_748835_0 ABC-2 family transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000001061 220.0
HFD2_k127_7490220_0 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009406 534.0
HFD2_k127_7490220_1 COG3911 Predicted ATPase - - - 0.00000000000000000000000000000000000000000000000000000001003 213.0
HFD2_k127_7490220_2 ABC transporter - - - 0.0006215 44.0
HFD2_k127_7501149_0 Family membership K08884 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 338.0
HFD2_k127_7501149_1 cell envelope organization K05807,K08309 - - 0.0000000000000000000000000000000000000000000000000000001704 211.0
HFD2_k127_7501149_2 histidine kinase A domain protein - - - 0.000000000000000000000001906 105.0
HFD2_k127_7509942_0 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000004192 237.0
HFD2_k127_7509942_2 Forkhead associated domain - - - 0.000000000000000000000000006069 122.0
HFD2_k127_7509942_3 iron-sulfur cluster assembly K07126,K13819 - - 0.0000000000000000009049 89.0
HFD2_k127_7511604_0 Domain of unknown function (DUF1768) K09935 - - 0.0000000000000000000000000000000000000000000000000000000001649 208.0
HFD2_k127_7511604_1 bacterial-type flagellum-dependent cell motility - - - 0.000000000000000000000000000000000000005388 154.0
HFD2_k127_7512805_0 Imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001089 282.0
HFD2_k127_7512805_1 cyclic nucleotide-binding - - - 0.000000000000000000000000000000000000000000000000000000001882 209.0
HFD2_k127_7512805_2 ATP:ADP antiporter activity K03301 - - 0.000000000000000000000000000000000000002955 163.0
HFD2_k127_7512805_3 cyclic nucleotide binding K00384,K10914,K16922 - 1.8.1.9 0.000000000000000000000000000000000000007905 158.0
HFD2_k127_7512805_4 rRNA (guanine-N2-)-methyltransferase activity - - - 0.0000000000000000004244 97.0
HFD2_k127_7520520_0 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.00000000000000001063 86.0
HFD2_k127_7520520_1 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000007467 77.0
HFD2_k127_7524010_0 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 394.0
HFD2_k127_7524010_2 peptidyl-tyrosine sulfation - - - 0.000005767 58.0
HFD2_k127_7524010_3 function. Source PGD - - - 0.000016 57.0
HFD2_k127_7531845_0 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 437.0
HFD2_k127_7531845_2 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate K01815 - 5.3.1.17 0.000000000000006419 74.0
HFD2_k127_7536578_0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 2.629e-226 711.0
HFD2_k127_7536578_1 Esterase PHB depolymerase K03932 - - 0.00000000000000000000000000000000000000000000000000000000006765 218.0
HFD2_k127_753883_0 Peptidyl-prolyl cis-trans K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000000002461 161.0
HFD2_k127_753883_1 secreted trypsin-like serine protease K01325 - 3.4.21.35 0.000000007874 68.0
HFD2_k127_7544081_0 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000002043 239.0
HFD2_k127_7544191_0 to choline dehydrogenase K00108 - 1.1.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 567.0
HFD2_k127_7544191_1 Fatty acid cis/trans isomerase (CTI) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003064 363.0
HFD2_k127_7544191_2 cellulase activity - - - 0.00004228 57.0
HFD2_k127_7545832_0 Protein of unknown function (DUF971) K03593 - - 0.000000000000000000000000000000000000071 147.0
HFD2_k127_7545832_1 Belongs to the carbohydrate kinase PfkB family K00847 - 2.7.1.4 0.00000000000000000000009066 110.0
HFD2_k127_7545832_2 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000001649 90.0
HFD2_k127_7546277_0 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000001993 189.0
HFD2_k127_7546277_1 Virulence - - - 0.0000000000000001968 91.0
HFD2_k127_7546277_2 - - - - 0.000000004858 67.0
HFD2_k127_7550182_0 Transcriptional regulator, CarD family K07736 - - 0.00000000000000000000000000000000000000003494 164.0
HFD2_k127_7551295_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000044 351.0
HFD2_k127_7551295_1 AI-2E family transporter - - - 0.0000000000000000000000000006873 128.0
HFD2_k127_7551295_2 COG1520 FOG WD40-like repeat - - - 0.00005409 55.0
HFD2_k127_7553814_0 thiolester hydrolase activity K06889 - - 0.0000000000000000000000000000000000000000001176 169.0
HFD2_k127_7553814_1 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000001205 168.0
HFD2_k127_7553814_2 Arsenical pump membrane protein - - - 0.000000008114 61.0
HFD2_k127_7554456_0 - - - - 0.00000000000000000000000000004054 123.0
HFD2_k127_7554456_1 Forkhead associated domain - - - 0.00000000000001188 85.0
HFD2_k127_7555639_1 - - - - 0.0000001886 55.0
HFD2_k127_7558233_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 374.0
HFD2_k127_7558233_1 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000000000000000000000000000000000078 239.0
HFD2_k127_7558233_2 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000000000000000003805 104.0
HFD2_k127_75615_0 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000973 268.0
HFD2_k127_75615_1 oligopeptide transporter, OPT family - - - 0.00000000000000000000000004275 110.0
HFD2_k127_7562639_0 Heat shock 70 kDa protein K04043 - - 0.000000000000000000000000000000000000000000000000000000000207 207.0
HFD2_k127_7562639_1 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000001765 138.0
HFD2_k127_7567841_0 Protein kinase domain K08884 - 2.7.11.1 0.000000000000002267 82.0
HFD2_k127_7571153_0 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 436.0
HFD2_k127_7571153_1 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000004396 145.0
HFD2_k127_7573532_0 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 547.0
HFD2_k127_7573532_1 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006128 312.0
HFD2_k127_7573532_2 Multidrug transporter MatE K03327 - - 0.000000000000000000000000000000000006228 154.0
HFD2_k127_7576480_0 bacterial-type flagellum-dependent cell motility - - - 0.00000000000000000000000000000000000000000000000000000000001643 227.0
HFD2_k127_7576480_1 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000003033 75.0
HFD2_k127_7578026_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 347.0
HFD2_k127_7578026_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003153 315.0
HFD2_k127_7578026_2 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000004984 252.0
HFD2_k127_7578026_3 Prolyl 4-hydroxylase alpha subunit homologues. - - - 0.0000000000000000000000000000000000000000000000000000005326 201.0
HFD2_k127_7582995_0 protein kinase activity K12132 - 2.7.11.1 0.00000006249 63.0
HFD2_k127_7595806_0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000002006 123.0
HFD2_k127_7595806_1 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000000000000004675 109.0
HFD2_k127_7598514_0 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004105 473.0
HFD2_k127_7598514_1 Sulfatase K01133 - 3.1.6.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 364.0
HFD2_k127_7598514_2 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007434 340.0
HFD2_k127_7598514_3 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.00000003524 62.0
HFD2_k127_7600262_0 UvrD/REP helicase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000009583 219.0
HFD2_k127_7600262_1 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000001902 140.0
HFD2_k127_7601865_0 Forkhead associated domain - - - 0.000000000000000000000000000001334 136.0
HFD2_k127_7601865_1 Forkhead associated domain - - - 0.000000000000007354 83.0
HFD2_k127_7605777_0 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 325.0
HFD2_k127_7605777_1 protein trimerization - - - 0.000000000000000000000000000003573 139.0
HFD2_k127_760805_0 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.0 1080.0
HFD2_k127_7612345_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007142 458.0
HFD2_k127_7616117_0 Calcineurin-like phosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 376.0
HFD2_k127_7616117_1 Sterol carrier protein domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004837 258.0
HFD2_k127_7616117_2 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000009903 131.0
HFD2_k127_7616117_3 Pentapeptide repeats (9 copies) - - - 0.00008725 54.0
HFD2_k127_761691_0 PAS domain K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 386.0
HFD2_k127_761691_1 Fatty acid desaturase K00508 - 1.14.19.3 0.00000000000000000000000000000000000009596 145.0
HFD2_k127_7617262_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000009546 176.0
HFD2_k127_7617262_1 Flagellar regulatory protein FleQ - - - 0.00000000000000003157 85.0
HFD2_k127_7634949_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003984 332.0
HFD2_k127_7635354_0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit K01844 - 5.4.3.3 1.336e-227 715.0
HFD2_k127_7635354_1 ABC-type transport system involved in multi-copper enzyme maturation permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001575 267.0
HFD2_k127_7635354_2 Dimerisation domain of d-ornithine 4,5-aminomutase K18011 - 5.4.3.3 0.000000000000000000004305 94.0
HFD2_k127_7635354_3 - - - - 0.000003071 58.0
HFD2_k127_7636575_0 Mur ligase family, catalytic domain K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004337 453.0
HFD2_k127_7636575_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family K00569 GO:0003674,GO:0003824,GO:0008119,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008757,GO:0010035,GO:0010038,GO:0016740,GO:0016741,GO:0032259,GO:0042221,GO:0046690,GO:0050896 2.1.1.67 0.0000000000000000000000000000000000000000000006546 176.0
HFD2_k127_7636575_2 Lysylphosphatidylglycerol synthase TM region - - - 0.0003288 48.0
HFD2_k127_7637333_0 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002786 274.0
HFD2_k127_7640972_0 ketosteroid isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008744 257.0
HFD2_k127_7644529_0 DNA polymerase K02336 GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.000154 50.0
HFD2_k127_7645636_0 PFAM regulator of chromosome condensation, RCC1 - - - 0.00000000000000000000000000000000000000000000000000000000891 211.0
HFD2_k127_7645636_2 Trypsin-like serine protease - - - 0.000001239 59.0
HFD2_k127_7647830_0 4Fe-4S dicluster domain K17723 - 1.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003571 529.0
HFD2_k127_7647830_1 PAS fold - - - 0.00000000000000000000000000000000000000000000000000000000000000004737 243.0
HFD2_k127_7647830_2 PFAM Protein kinase domain K08309 - - 0.000000000000000000000000000000000007875 148.0
HFD2_k127_7651288_0 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000006068 173.0
HFD2_k127_7651288_1 structural constituent of cell wall - - - 0.000179 52.0
HFD2_k127_7660572_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002322 273.0
HFD2_k127_7660572_1 D-alanyl-D-alanine carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000007242 201.0
HFD2_k127_7660572_2 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000004549 113.0
HFD2_k127_7660572_3 Ribosomal L32p protein family K02911 - - 0.0000000000000000000002835 100.0
HFD2_k127_7663984_0 Predicted methyltransferase regulatory domain - - - 0.00000000000000000000000000004925 128.0
HFD2_k127_7665344_0 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 413.0
HFD2_k127_7665344_1 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007998 392.0
HFD2_k127_7665344_2 Glycoside hydrolase family 44 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005335 362.0
HFD2_k127_7665344_3 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000182 64.0
HFD2_k127_7674264_0 SERine Proteinase INhibitors K13963 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007553 371.0
HFD2_k127_7674264_1 - - - - 0.000007168 58.0
HFD2_k127_7674264_2 histone H2A K63-linked ubiquitination - - - 0.00005073 55.0
HFD2_k127_7675129_0 PEGA domain - - - 0.00000000000000000000000000000000000000000000000000000000000261 224.0
HFD2_k127_7675129_2 Belongs to the peptidase S8 family - - - 0.0002708 49.0
HFD2_k127_7689102_0 Family membership - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003299 334.0
HFD2_k127_7689102_1 TRANSCRIPTIONal K03892 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 313.0
HFD2_k127_7689102_2 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000006965 226.0
HFD2_k127_7691460_0 HEAT repeats - - - 0.00000000000000000000000000000000000000000000000000000000008627 222.0
HFD2_k127_7691460_1 - - - - 0.000000000000000000000000000001517 138.0
HFD2_k127_7693408_0 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000001317 206.0
HFD2_k127_7693408_1 membrane transporter protein K07090 - - 0.000000000000000000000000006107 113.0
HFD2_k127_7699956_0 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 3.928e-212 672.0
HFD2_k127_7699956_1 Sigma-54 interaction domain K07714,K07715 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 548.0
HFD2_k127_7699956_2 HAMP domain K07711 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008168 334.0
HFD2_k127_7701584_0 glyoxalase III activity - - - 0.000000000000000000000000000000000000000000002485 173.0
HFD2_k127_7701584_1 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000005352 151.0
HFD2_k127_7701939_0 nickel-dependent hydrogenase large subunit K06281 - 1.12.99.6 2.214e-266 824.0
HFD2_k127_7701939_1 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.000000000000000000000000000000000000000000005735 171.0
HFD2_k127_7701939_2 - - - - 0.0001958 47.0
HFD2_k127_7704023_0 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000006993 146.0
HFD2_k127_7706979_0 D-alanyl-D-alanine carboxypeptidase K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 395.0
HFD2_k127_7706979_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000003189 238.0
HFD2_k127_7706979_2 phosphoprotein phosphatase activity - - - 0.0000000000000000000004243 101.0
HFD2_k127_7707983_0 Thermolysin metallopeptidase, alpha-helical domain K01400,K08777 GO:0005575,GO:0005576 3.4.24.28 0.00000000000000000001188 107.0
HFD2_k127_7708116_0 Family membership K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 316.0
HFD2_k127_7708116_1 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000001132 118.0
HFD2_k127_7714397_1 TonB dependent receptor K16089 - - 0.000000000000000000000000000000000000000000000002192 179.0
HFD2_k127_7714397_2 HmuY protein - - - 0.00000000000002376 82.0
HFD2_k127_7715410_0 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009076 385.0
HFD2_k127_7715410_1 cell envelope organization K05807,K08309 - - 0.000000000000000000000000000000000187 152.0
HFD2_k127_7728740_0 protein domain, possibly involved in tellurite resistance - - - 0.00000000000000000000000000000000000001877 154.0
HFD2_k127_7728740_1 hemerythrin HHE cation binding domain - - - 0.000000000628 69.0
HFD2_k127_773067_0 PD-(D/E)XK nuclease superfamily - - - 1.273e-300 960.0
HFD2_k127_773067_1 UvrD/REP helicase N-terminal domain - - - 5.621e-264 839.0
HFD2_k127_7732647_0 DEAD DEAH box helicase - - - 1.06e-287 903.0
HFD2_k127_7732647_1 type IV pilus secretin PilQ K02666 - - 0.00000000000000000003311 100.0
HFD2_k127_7732647_2 zinc-ribbon domain - - - 0.000000001508 65.0
HFD2_k127_7733411_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001491 257.0
HFD2_k127_7733411_1 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000005447 207.0
HFD2_k127_7752702_0 A disintegrin and metalloproteinase with thrombospondin motifs K08624,K08630,K08632 - - 0.000001496 59.0
HFD2_k127_7757070_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009566 415.0
HFD2_k127_7757070_1 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008967 410.0
HFD2_k127_7757070_2 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000000000000000000000000000002366 225.0
HFD2_k127_77754_0 Lysine methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000118 198.0
HFD2_k127_77754_1 Putative auto-transporter adhesin, head GIN domain - - - 0.0000000000002837 80.0
HFD2_k127_77754_2 Leucine-rich repeat (LRR) protein - - - 0.0000003464 63.0
HFD2_k127_7797258_0 AAA domain - - - 0.0000000000000000000000000000000000000000000002957 189.0
HFD2_k127_7797258_1 CAAX amino terminal protease family K07052 - - 0.000004843 59.0
HFD2_k127_7797258_2 heat shock protein binding K03686 - - 0.00004291 52.0
HFD2_k127_780217_0 amp-dependent synthetase and ligase K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006011 475.0
HFD2_k127_780217_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 303.0
HFD2_k127_780217_2 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000003405 71.0
HFD2_k127_780217_3 Phosphopantetheine attachment site - - - 0.000000004354 64.0
HFD2_k127_7803733_0 TonB dependent receptor K16089 - - 0.0000000003549 73.0
HFD2_k127_7803733_1 Transcriptional regulator, AraC family - - - 0.000009469 56.0
HFD2_k127_7804458_0 acetylesterase activity K14731 - 3.1.1.83 0.00000000000000000000000000000000000000000000000000000000000009152 226.0
HFD2_k127_7805853_0 Histone deacetylase domain K04768 - - 0.000000000000000000000000000000000000000000000006624 177.0
HFD2_k127_7805853_1 PLD-like domain - - - 0.0000000000000000000000000000000003113 147.0
HFD2_k127_7805853_2 Peptidoglycan-binding domain 1 protein - - - 0.0000000000005578 78.0
HFD2_k127_7805853_4 - - - - 0.0003133 43.0
HFD2_k127_7812863_0 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001156 287.0
HFD2_k127_7812863_1 phosphorelay signal transduction system K10941 - - 0.000000000000000000000000000000000000000000000002041 180.0
HFD2_k127_7812863_3 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000005819 131.0
HFD2_k127_7812863_4 PFAM YbaK prolyl-tRNA synthetase associated region K19055 - - 0.0000001276 60.0
HFD2_k127_7815136_0 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003453 364.0
HFD2_k127_7815136_1 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000001128 244.0
HFD2_k127_7815136_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000001231 194.0
HFD2_k127_781531_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003836 582.0
HFD2_k127_781531_1 Acetyltransferase (GNAT) domain - - - 0.000007465 55.0
HFD2_k127_7816161_0 anaphase-promoting complex binding - - - 0.00000000006658 69.0
HFD2_k127_7818710_0 Esterase PHB depolymerase - - - 0.000009552 57.0
HFD2_k127_7822951_0 beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004904 312.0
HFD2_k127_7823352_0 cell envelope organization K05807,K08309 - - 0.000000000000000000781 98.0
HFD2_k127_7823352_1 - - - - 0.000006163 58.0
HFD2_k127_7823352_2 - - - - 0.0002875 53.0
HFD2_k127_7826176_0 NADP Oxidoreductase K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007345 336.0
HFD2_k127_7826176_1 Belongs to the serpin family K13963 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 304.0
HFD2_k127_7826176_2 Bacterial protein of unknown function (DUF899) - - - 0.00000000000000000000000000000000003865 138.0
HFD2_k127_7826176_3 TatD related DNase K03424 GO:0000175,GO:0000302,GO:0000738,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0009056,GO:0009057,GO:0009636,GO:0009987,GO:0010035,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0016896,GO:0019439,GO:0034641,GO:0034655,GO:0042221,GO:0042493,GO:0042542,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046700,GO:0046872,GO:0050896,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901700 - 0.0000000000000000000000000000000006569 131.0
HFD2_k127_7829072_0 Von Willebrand factor type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009549 269.0
HFD2_k127_7829072_1 Cytochrome c K03889 - - 0.0000000000000004117 87.0
HFD2_k127_7841298_0 Vault protein inter-alpha-trypsin domain - - - 4.744e-296 954.0
HFD2_k127_7860614_0 - - - - 2.13e-202 663.0
HFD2_k127_7860614_2 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02667 - - 0.0000000000000000000000000000000000000000000000000000000648 201.0
HFD2_k127_7865530_0 4-amino-4-deoxy-L-arabinose transferase activity K02277 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000001289 249.0
HFD2_k127_7865530_1 Acyltransferase - - - 0.0000000000000000000000000000000007693 152.0
HFD2_k127_7873906_0 Ca-dependent carbohydrate-binding module xylan-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007948 417.0
HFD2_k127_7873906_1 amine oxidase K01854 - 5.4.99.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005238 310.0
HFD2_k127_7873906_2 Protein of unknown function (DUF1501) - - - 0.0000000002008 64.0
HFD2_k127_787811_0 - - - - 0.0000000000000000000000000000000000000000000000000000005657 206.0
HFD2_k127_7879657_0 - K03561,K12287 - - 0.00000000000000000000000000002878 131.0
HFD2_k127_7879657_1 Beta-L-arabinofuranosidase, GH127 - - - 0.0000000003012 68.0
HFD2_k127_7879657_2 - - - - 0.00002025 51.0
HFD2_k127_7891360_0 ABC-2 family transporter protein - - - 6.939e-244 777.0
HFD2_k127_7891360_1 Chitin synthase K00752 - 2.4.1.212 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 322.0
HFD2_k127_7895153_0 Protein kinase domain K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000001069 274.0
HFD2_k127_7896548_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 6.189e-206 653.0
HFD2_k127_7896548_1 Cobalamin-independent synthase, Catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008864 460.0
HFD2_k127_7898261_0 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 354.0
HFD2_k127_7898452_0 Periplasmic protein TonB links inner and outer membranes - - - 1.758e-210 679.0
HFD2_k127_7898452_2 Short repeat of unknown function (DUF308) - - - 0.00000000002147 73.0
HFD2_k127_790245_0 glutamine synthetase K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000945 607.0
HFD2_k127_790245_1 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000000000000006704 202.0
HFD2_k127_790245_2 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.0000000000000000000000000000000000000000006956 170.0
HFD2_k127_790245_3 Family membership K08884,K12132 - 2.7.11.1 0.0000001213 62.0
HFD2_k127_7913012_0 Galactose oxidase, central domain - - - 0.000001775 61.0
HFD2_k127_7914845_0 Carbohydrate-selective porin, OprB family K16080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009003 359.0
HFD2_k127_7914845_1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000000003048 88.0
HFD2_k127_7917840_0 PFAM sigma-54 factor interaction domain-containing protein K07715 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 364.0
HFD2_k127_7917840_1 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002352 298.0
HFD2_k127_7917840_2 protein trimerization - - - 0.000000000000000000000000000000000000000000000000000004015 207.0
HFD2_k127_7917840_3 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00006289 46.0
HFD2_k127_7919122_0 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 6.044e-205 659.0
HFD2_k127_7919122_1 Belongs to the phosphoglycerate mutase family K15634 - 5.4.2.12 0.000000000000000000000000000000000000000000000001244 182.0
HFD2_k127_7919122_2 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000000000001314 115.0
HFD2_k127_7919122_3 serine threonine protein kinase K12132 - 2.7.11.1 0.000000004797 58.0
HFD2_k127_7919122_4 Methyltransferase domain - - - 0.00000008695 57.0
HFD2_k127_7919127_0 Protein of unknown function (DUF4011) - - - 0.000000000000000000000000000001218 130.0
HFD2_k127_7919127_1 Domain of unknown function (DUF5122) beta-propeller - - - 0.00000000000000000000000000001213 132.0
HFD2_k127_7921723_0 beta-lactamase activity K07126 - - 0.0000000000000000000000000000000000000000000002153 186.0
HFD2_k127_792241_0 PFAM Formylglycine-generating sulfatase enzyme K12132 - 2.7.11.1 1.803e-195 634.0
HFD2_k127_792241_1 SOS response associated peptidase (SRAP) - - - 0.000000000000000000000000000000000000000000001335 177.0
HFD2_k127_792241_2 PFAM Formylglycine-generating sulfatase enzyme K12132 - 2.7.11.1 0.0000000000000000000000000000000001493 136.0
HFD2_k127_792674_0 Surface antigen K07277,K07278 - - 0.000000000000000000000000000000000000000000000000000000000002598 217.0
HFD2_k127_792674_1 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000000000000000000000000000000000000001635 190.0
HFD2_k127_7934472_0 Binding-protein-dependent transport system inner membrane component K02033,K12369,K13890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 314.0
HFD2_k127_7934472_1 Sulfatase-modifying factor enzyme 1 K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000005224 222.0
HFD2_k127_7935014_0 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 376.0
HFD2_k127_7935014_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004293 279.0
HFD2_k127_7946634_0 amine dehydrogenase activity - - - 0.0001055 55.0
HFD2_k127_7952734_0 hydrolase, family 65, central catalytic K10231 - 2.4.1.230 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003952 470.0
HFD2_k127_7955170_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003251 284.0
HFD2_k127_7971517_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 414.0
HFD2_k127_7971517_1 PspA/IM30 family K03969 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 347.0
HFD2_k127_7971517_2 - - - - 0.00000000000000000000000000000002846 130.0
HFD2_k127_7973939_0 PFAM sigma-54 factor interaction domain-containing protein K07715 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006935 348.0
HFD2_k127_7973939_1 Protein serine threonine phosphatase K20074 - 3.1.3.16 0.0000000000003939 72.0
HFD2_k127_7975150_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00324 - 1.6.1.2 2.027e-197 629.0
HFD2_k127_7975150_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009899 569.0
HFD2_k127_7979779_0 Heat shock 70 kDa protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001479 260.0
HFD2_k127_7979779_1 - - - - 0.000000000000000000000000000000006888 138.0
HFD2_k127_7980256_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000008252 233.0
HFD2_k127_7980256_1 FecR protein - - - 0.0000000000003464 81.0
HFD2_k127_7980256_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000006886 65.0
HFD2_k127_7980256_3 Calcium-binding EGF domain - - - 0.0003314 43.0
HFD2_k127_7981640_0 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000001528 238.0
HFD2_k127_798203_0 SMART PAS domain containing protein K13924 - 2.1.1.80,3.1.1.61 2.273e-320 1005.0
HFD2_k127_798203_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002637 250.0
HFD2_k127_798203_2 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000001181 166.0
HFD2_k127_798203_3 - - - - 0.0000000000000000000000000000005257 129.0
HFD2_k127_7988200_0 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005769 301.0
HFD2_k127_7988200_1 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000001012 207.0
HFD2_k127_7988200_2 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase K07559 - - 0.0000000000000000000000000000000000000000000000000008677 192.0
HFD2_k127_7988200_3 - - - - 0.0000000000000000000000000000000000000000002205 166.0
HFD2_k127_7988200_4 Transcriptional regulator - - - 0.0000000000000000000000000000000000000001493 158.0
HFD2_k127_7988200_5 - - - - 0.0000000000104 74.0
HFD2_k127_7994698_0 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001405 276.0
HFD2_k127_7994698_1 PEGA domain - - - 0.00000000000000000000000000000000000000000000000000004246 201.0
HFD2_k127_7994698_2 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000001187 166.0
HFD2_k127_7994698_3 PFAM Formylglycine-generating sulfatase enzyme K12132 - 2.7.11.1 0.000000000000000000000000000001155 141.0
HFD2_k127_7994698_4 Beta-L-arabinofuranosidase, GH127 - - - 0.0003382 53.0
HFD2_k127_8001446_0 Elongator protein 3, MiaB family, Radical SAM - - - 1.212e-306 952.0
HFD2_k127_8002638_0 Domain of unknown function (DUF4388) - - - 0.00000000000001444 79.0
HFD2_k127_8002638_1 spectrin binding - - - 0.0009721 46.0
HFD2_k127_8003820_0 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 452.0
HFD2_k127_8003820_1 Protein of unknown function (DUF3105) - - - 0.000000000000000000000000000000001082 143.0
HFD2_k127_8003820_2 ribonuclease BN K07058 - - 0.0000000006963 71.0
HFD2_k127_8010577_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009066 422.0
HFD2_k127_8010577_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001218 289.0
HFD2_k127_8012144_0 PFAM ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 372.0
HFD2_k127_8012144_1 R3H domain K06346 - - 0.00000000000000000000000000000000000000000008917 166.0
HFD2_k127_8012144_2 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000003764 115.0
HFD2_k127_8012144_3 - - - - 0.00000000000000000000000002169 111.0
HFD2_k127_8012653_0 glycoside hydrolase family 2 sugar binding K01192 - 3.2.1.25 1.672e-226 729.0
HFD2_k127_8012653_1 Alpha/beta hydrolase family K06999 - - 0.00000000000000000000000000000000002296 144.0
HFD2_k127_8012653_2 Protein of unknown function (DUF861) K06995 - - 0.000000000000000000000000006018 115.0
HFD2_k127_8012653_3 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000001071 115.0
HFD2_k127_8016279_0 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033,K13890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 371.0
HFD2_k127_8016279_1 belongs to the thioredoxin family K03671,K05838,K07390,K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 287.0
HFD2_k127_8016279_2 Binding-protein-dependent transport system inner membrane component K02034,K15582 - - 0.000000000000000000000000000000000000000000000000000000000003464 222.0
HFD2_k127_8016279_3 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000000000000000002024 208.0
HFD2_k127_8016279_4 PFAM ABC transporter - - - 0.000000000000000000000000000007021 134.0
HFD2_k127_8016279_5 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.000000000000000000000000003499 112.0
HFD2_k127_8017244_0 pyrroloquinoline quinone binding - - - 0.0000000000000000000000000000000000000000000000001938 185.0
HFD2_k127_8017244_1 Fungal chitosanase of glycosyl hydrolase group 75 - - - 0.00000000000000000000000000000000000000000001153 176.0
HFD2_k127_8017244_2 metallopeptidase activity - - - 0.00002779 55.0
HFD2_k127_8030225_0 C-terminal, D2-small domain, of ClpB protein - - - 1.975e-301 941.0
HFD2_k127_8030225_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 3.336e-252 804.0
HFD2_k127_8037499_0 Plant intracellular Ras-group-related LRR protein - - - 0.00000000004585 76.0
HFD2_k127_8037499_2 NB-ARC domain - - - 0.0003382 53.0
HFD2_k127_8039133_0 Pyridoxal-phosphate dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 315.0
HFD2_k127_8039133_1 protein import - - - 0.000000001245 69.0
HFD2_k127_8039133_2 cell wall organization - - - 0.000001178 60.0
HFD2_k127_8041521_0 Glycosyl hydrolase family 20, domain 2 K12373 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 417.0
HFD2_k127_8043847_0 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 1.92e-220 700.0
HFD2_k127_8043847_1 (ABC) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 422.0
HFD2_k127_8043847_2 alcohol dehydrogenase K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004814 406.0
HFD2_k127_8043847_3 Esterase PHB depolymerase K03932 - - 0.0000000000000000000000000000000000000000000000000000000000001682 226.0
HFD2_k127_8050072_0 dioxygenase K00464 - 1.13.11.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004967 394.0
HFD2_k127_8050072_1 Virulence activator alpha C-term - - - 0.000007015 52.0
HFD2_k127_8051083_1 Domain of unknown function (DUF4331) - - - 0.00000000000000000232 88.0
HFD2_k127_8051083_2 P-aminobenzoate N-oxygenase AurF - - - 0.000000000003046 79.0
HFD2_k127_8051083_3 Alpha beta hydrolase - - - 0.00003528 55.0
HFD2_k127_8051083_4 X-Pro dipeptidyl-peptidase (S15 family) K06889 - - 0.0006041 51.0
HFD2_k127_805136_0 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001896 295.0
HFD2_k127_805136_1 polysaccharide catabolic process K01179,K05991 - 3.2.1.123,3.2.1.4 0.000000002555 67.0
HFD2_k127_8052215_0 acetyltransferase - - - 0.000000000000000000000000000000000000001057 160.0
HFD2_k127_8052215_1 - - - - 0.000000000000000000000003489 110.0
HFD2_k127_8052215_2 PFAM Alpha beta hydrolase fold-3 domain protein - - - 0.000000000000000000007138 95.0
HFD2_k127_8052215_3 - - - - 0.000000000000003901 83.0
HFD2_k127_8052236_0 Belongs to the pseudouridine synthase RsuA family K06178,K06182 - 5.4.99.21,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 355.0
HFD2_k127_8052236_1 TPM domain K06872 - - 0.000000000000000000000000000000000000000000002971 175.0
HFD2_k127_8052236_2 serine-type peptidase activity - - - 0.0000000004285 65.0
HFD2_k127_8052307_0 Vault protein inter-alpha-trypsin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 596.0
HFD2_k127_8052307_1 DNA-templated transcription, initiation K03088 - - 0.000000009606 65.0
HFD2_k127_8054701_0 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000002482 158.0
HFD2_k127_8054701_1 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000003499 142.0
HFD2_k127_8054985_0 Protein kinase domain K08884 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000009331 218.0
HFD2_k127_8055042_0 cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000143 277.0
HFD2_k127_8055042_1 2OG-Fe(II) oxygenase - - - 0.00000000000000000000000000002877 129.0
HFD2_k127_8055042_2 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000003882 89.0
HFD2_k127_8055042_3 Sterol desaturase - - - 0.0003547 46.0
HFD2_k127_8061046_0 Tim44 K15539 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009842 396.0
HFD2_k127_8061046_1 Membrane K08988 - - 0.0000000000000000000004579 105.0
HFD2_k127_806152_0 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001273 296.0
HFD2_k127_806152_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000001569 120.0
HFD2_k127_8071114_1 - - - - 0.0000000000000002547 89.0
HFD2_k127_8075507_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 394.0
HFD2_k127_8075507_1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.000000000000000000000000000000002128 134.0
HFD2_k127_8075507_2 Sigma 54 modulation protein / S30EA ribosomal protein K05808 - - 0.000000000000000000000000002044 116.0
HFD2_k127_8081614_1 - - - - 0.00000000000000833 87.0
HFD2_k127_8082046_0 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007133 370.0
HFD2_k127_8082046_2 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000001036 111.0
HFD2_k127_8082985_0 Bacterial regulatory protein, Fis family K13599 - - 5.505e-197 627.0
HFD2_k127_8082985_1 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 315.0
HFD2_k127_8082985_2 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.00000000000000000000000000000000000000000000007894 177.0
HFD2_k127_8082985_3 Serine aminopeptidase, S33 K03928 - 3.1.1.1 0.0000000000000000000000000000006781 132.0
HFD2_k127_8082985_4 - - - - 0.00000000000000000000003601 105.0
HFD2_k127_8091673_0 DNA ligase K01971 - 6.5.1.1 5.483e-222 722.0
HFD2_k127_8091673_2 Protein of unknown function DUF72 - - - 0.00000000002129 67.0
HFD2_k127_8092458_0 Sulfate transporter antisigma-factor antagonist STAS K01673,K03321 - 4.2.1.1 7.723e-197 641.0
HFD2_k127_8092458_1 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003391 426.0
HFD2_k127_8092458_2 PFAM RNA binding S1 domain protein K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000003383 246.0
HFD2_k127_8092458_3 PPIC-type PPIASE domain - - - 0.000000000000000000001966 102.0
HFD2_k127_8092458_4 GMC oxidoreductase K00108 - 1.1.99.1 0.000000000002172 72.0
HFD2_k127_8094555_0 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007752 330.0
HFD2_k127_810076_0 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000048 361.0
HFD2_k127_810076_1 Roadblock/LC7 domain - - - 0.000000000000000000000000000000000000000003064 166.0
HFD2_k127_810076_2 protein kinase activity K12132 - 2.7.11.1 0.00000000009383 72.0
HFD2_k127_810076_4 Peptidylprolyl isomerase K03770 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0008150,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031233,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0061077,GO:0071575,GO:0071944,GO:0098552 5.2.1.8 0.00001555 56.0
HFD2_k127_8112356_0 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000139 267.0
HFD2_k127_8112356_1 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.0000000000000000000000000000000000000000000000000000002828 198.0
HFD2_k127_8112356_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000001728 178.0
HFD2_k127_8112356_3 - - - - 0.00000000000000001741 91.0
HFD2_k127_811481_0 - - - - 0.0000000001517 67.0
HFD2_k127_811481_1 cellulose binding - - - 0.0002586 53.0
HFD2_k127_8118870_0 3'-5' exonuclease K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 321.0
HFD2_k127_8118870_1 - - - - 0.0000000000001188 80.0
HFD2_k127_8118870_2 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000001144 68.0
HFD2_k127_8119994_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000005973 234.0
HFD2_k127_8119994_1 DNA-binding regulatory protein K03088 - - 0.0000000000000000000000001217 116.0
HFD2_k127_8119994_2 Cytochrome c - - - 0.000001186 55.0
HFD2_k127_8121140_0 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009392 272.0
HFD2_k127_8121140_1 Phosphoinositide phospholipase C, Ca2+-dependent - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007431 276.0
HFD2_k127_8124457_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006969 551.0
HFD2_k127_8124457_1 PilZ domain - - - 0.00000000000000003433 86.0
HFD2_k127_8124541_0 Membrane K08994 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 289.0
HFD2_k127_8124541_1 Choline/ethanolamine kinase K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000003942 259.0
HFD2_k127_8124541_2 rRNA methyltransferase activity K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.00000000000000000000000000000000000000000000000000004165 194.0
HFD2_k127_8125366_0 Elongator protein 3, MiaB family, Radical SAM K06937 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 434.0
HFD2_k127_8125366_1 Elongator protein 3, MiaB family, Radical SAM K06937 - - 0.00000000000000000000000000000000000000000000000000000000000000000004285 242.0
HFD2_k127_8125366_2 Enoyl-(Acyl carrier protein) reductase K00034,K03366 - 1.1.1.304,1.1.1.47,1.1.1.76 0.0000000000000000000000000000000000000000000000000000000000000000002922 237.0
HFD2_k127_8127471_0 of the alpha beta superfamily K06889 - - 0.0000000000000000000000000000000000000000002205 166.0
HFD2_k127_8127471_1 deoxyhypusine monooxygenase activity - - - 0.000000000000000000002285 109.0
HFD2_k127_8131401_0 Cytochrome c K00412 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006818 479.0
HFD2_k127_8132138_0 PFAM PHP domain protein K01104 - 3.1.3.48 0.0000000000000000000000000000000000000000000000000000000000000000000143 239.0
HFD2_k127_8132138_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474 - - 0.00000000000000000000000003202 111.0
HFD2_k127_8135775_0 Belongs to the glycosyl hydrolase 13 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007226 287.0
HFD2_k127_8135775_1 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.000003395 59.0
HFD2_k127_8136980_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 373.0
HFD2_k127_8136980_1 phosphate ion binding - - - 0.00000000000000000000000000000000000000000000000000001166 210.0
HFD2_k127_8136980_2 Cytochrome c K00406,K03889 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000001766 111.0
HFD2_k127_8137296_0 Cytochrome c554 and c-prime K01119 - 3.1.3.6,3.1.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000005835 261.0
HFD2_k127_8137296_1 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000003012 166.0
HFD2_k127_8137384_0 PFAM sigma-54 factor interaction domain-containing protein K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006656 471.0
HFD2_k127_8137384_1 NHL repeat - - - 0.00000000000000000000000000000000000000000002591 177.0
HFD2_k127_8137384_2 Esterase PHB depolymerase - - - 0.0001347 53.0
HFD2_k127_8150430_0 RESPONSE REGULATOR receiver - - - 0.0000000000000000001983 96.0
HFD2_k127_8150430_1 NUDIX domain - - - 0.0001134 46.0
HFD2_k127_8150430_2 - - - - 0.0003098 51.0
HFD2_k127_8151589_0 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004897 366.0
HFD2_k127_8152861_0 Zinc-dependent metalloprotease - - - 0.0000000000000000000000000002256 121.0
HFD2_k127_8152861_1 Catalyzes a cyclopropane ring-opening reaction, the irreversible conversion of 1-aminocyclopropane-1-carboxylate (ACC) to ammonia and alpha-ketobutyrate. Allows growth on ACC as a nitrogen source K01505,K05396 - 3.5.99.7,4.4.1.15 0.0000000000001022 83.0
HFD2_k127_8152861_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000001279 74.0
HFD2_k127_8152861_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins - - - 0.00000214 61.0
HFD2_k127_8154621_0 N-terminal domain of unknown function (DUF4140) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 395.0
HFD2_k127_8154783_0 PFAM regulator of chromosome condensation, RCC1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003368 297.0
HFD2_k127_8154783_1 Family membership K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000004503 171.0
HFD2_k127_8163218_0 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000005075 164.0
HFD2_k127_8163218_1 PFAM Hemolysin-type calcium-binding repeat (2 copies) - - - 0.000000000000000000000000000000000000000000217 172.0
HFD2_k127_816418_0 Domain of unknown function (DUF4347) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001085 247.0
HFD2_k127_816418_1 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000008624 121.0
HFD2_k127_816418_2 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000007273 83.0
HFD2_k127_816418_3 regulation of response to stimulus K13730 - - 0.0000000001154 74.0
HFD2_k127_816418_4 calcium- and calmodulin-responsive adenylate cyclase activity K01186,K01406 - 3.2.1.18,3.4.24.40 0.0000000004964 72.0
HFD2_k127_8168617_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 6.038e-226 712.0
HFD2_k127_8168617_1 General secretion pathway protein F K02455,K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 435.0
HFD2_k127_8168617_2 Prokaryotic N-terminal methylation motif K02457 - - 0.00000000000000000000000000000000000000000000000000000000009455 215.0
HFD2_k127_8168617_4 Type II secretion system (T2SS), protein J K02459 - - 0.000000000000000000000000000000000001625 144.0
HFD2_k127_8168617_5 Prokaryotic N-terminal methylation motif K02458 - - 0.0000000000000000000000000000000006389 143.0
HFD2_k127_8168617_6 general secretion pathway protein K02456 - - 0.000000000000000000001489 100.0
HFD2_k127_8170926_0 Family membership K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000362 290.0
HFD2_k127_8170926_1 DNA-binding regulatory protein K03088 - - 0.0000000000000000000000000000000000000000000001486 179.0
HFD2_k127_8171962_0 Vault protein inter-alpha-trypsin domain - - - 1.746e-211 698.0
HFD2_k127_8171962_1 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000000001008 192.0
HFD2_k127_8174029_0 beta-fructofuranosidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001075 271.0
HFD2_k127_8174029_1 methyltransferase - - - 0.000000000000000000000000000000001792 141.0
HFD2_k127_8174029_2 oligosaccharyl transferase activity - - - 0.00000277 58.0
HFD2_k127_8174029_3 - - - - 0.00001904 57.0
HFD2_k127_8174029_4 - - - - 0.0004119 51.0
HFD2_k127_8196857_0 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007713 332.0
HFD2_k127_8196857_1 PFAM ABC transporter K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 317.0
HFD2_k127_8196857_2 Barrel-sandwich domain of CusB or HlyD membrane-fusion K01993 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0071944 - 0.000001322 53.0
HFD2_k127_8196857_3 YsiA-like protein, C-terminal region - - - 0.000001509 54.0
HFD2_k127_8204914_0 Two component transcriptional regulator, winged helix family K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005887 321.0
HFD2_k127_8204914_1 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000009176 202.0
HFD2_k127_8209795_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000322 309.0
HFD2_k127_8220040_0 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000005608 198.0
HFD2_k127_8220040_1 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000007986 162.0
HFD2_k127_8220040_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000001747 105.0
HFD2_k127_8223029_0 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 300.0
HFD2_k127_822582_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA - - - 0.00000000000000000000000000000000000000000000000000000000000000001097 256.0
HFD2_k127_8227252_0 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 532.0
HFD2_k127_8227252_1 Protein of unknown function (DUF1211) - - - 0.000000000000000000000000000000000001535 146.0
HFD2_k127_8228551_0 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005422 392.0
HFD2_k127_8228551_1 enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 347.0
HFD2_k127_8228551_2 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000001986 124.0
HFD2_k127_8229537_0 malate quinone oxidoreductase K00116 - 1.1.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006968 306.0
HFD2_k127_8229537_1 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000193 139.0
HFD2_k127_8241323_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 339.0
HFD2_k127_8241323_1 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000000000000000000000000000001642 140.0
HFD2_k127_8241323_2 PFAM band 7 protein - - - 0.0000000000000000000000000000000187 131.0
HFD2_k127_8241782_0 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 331.0
HFD2_k127_8241782_1 ATP dependent DNA ligase domain protein K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000001158 269.0
HFD2_k127_8241782_2 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000000000000000000000008277 187.0
HFD2_k127_8256008_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007683 282.0
HFD2_k127_8256008_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000006343 201.0
HFD2_k127_8256008_2 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000007706 122.0
HFD2_k127_8256008_3 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000006465 103.0
HFD2_k127_8256008_4 - - - - 0.000002243 56.0
HFD2_k127_8270634_0 LytTr DNA-binding domain K02477 - - 0.00000000000000000000000000000000000000353 158.0
HFD2_k127_8270634_1 Histidine kinase K08082 - 2.7.13.3 0.000000000000000000000000000000004468 143.0
HFD2_k127_8274680_0 AlkA N-terminal domain K13529,K13530 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005374 508.0
HFD2_k127_8278622_0 hydrolase activity, hydrolyzing O-glycosyl compounds - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 542.0
HFD2_k127_8278622_1 Alpha-amylase domain K01176 - 3.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001538 278.0
HFD2_k127_8278826_0 DUF3160 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000498 421.0
HFD2_k127_8278826_1 - - - - 0.000000000002104 79.0
HFD2_k127_8281240_0 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006355 392.0
HFD2_k127_8281240_1 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 362.0
HFD2_k127_8281240_2 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.00000000000007158 74.0
HFD2_k127_828608_0 cytochrome C peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 417.0
HFD2_k127_8294192_0 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000001237 166.0
HFD2_k127_8298286_0 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 346.0
HFD2_k127_8301816_0 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002498 295.0
HFD2_k127_8303642_0 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007443 523.0
HFD2_k127_8305119_0 Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003199 261.0
HFD2_k127_8305119_1 peptidyl-tyrosine sulfation - - - 0.000001833 53.0
HFD2_k127_8306508_0 Tryptophan halogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009716 329.0
HFD2_k127_8306508_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007341 266.0
HFD2_k127_8306508_3 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000003814 182.0
HFD2_k127_8306508_4 Alkyl hydroperoxide reductase K03564 - 1.11.1.15 0.00000000000000000000000000000000000008069 147.0
HFD2_k127_8306508_5 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.000000000000000000000000000000008341 130.0
HFD2_k127_8310923_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007372 386.0
HFD2_k127_8310923_1 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000004652 96.0
HFD2_k127_8315332_0 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 580.0
HFD2_k127_8315332_1 Acyltransferase family - - - 0.000000000000000000000000000000002072 144.0
HFD2_k127_8315332_2 Leucine-rich repeat (LRR) protein - - - 0.0001866 50.0
HFD2_k127_8318_0 alpha/beta hydrolase fold K22318 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008709 368.0
HFD2_k127_8318_1 WGR domain protein - - - 0.00000000000000004044 90.0
HFD2_k127_8318_2 protein-DNA loading ATPase activity K10754 GO:0000122,GO:0000166,GO:0000723,GO:0000731,GO:0000902,GO:0000904,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005657,GO:0005663,GO:0005694,GO:0005730,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006278,GO:0006281,GO:0006283,GO:0006289,GO:0006296,GO:0006297,GO:0006301,GO:0006355,GO:0006357,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007004,GO:0007049,GO:0007275,GO:0007399,GO:0008047,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009653,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010833,GO:0016043,GO:0016358,GO:0017076,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019725,GO:0019904,GO:0019985,GO:0022008,GO:0022402,GO:0030030,GO:0030154,GO:0030182,GO:0030234,GO:0030554,GO:0031175,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031974,GO:0031981,GO:0032200,GO:0032201,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032989,GO:0032990,GO:0032991,GO:0033260,GO:0033554,GO:0033683,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042276,GO:0042592,GO:0042769,GO:0043085,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043565,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044464,GO:0044786,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0048468,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048666,GO:0048667,GO:0048699,GO:0048731,GO:0048812,GO:0048813,GO:0048856,GO:0048858,GO:0048869,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051276,GO:0051606,GO:0051716,GO:0060249,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070987,GO:0071704,GO:0071840,GO:0071897,GO:0080090,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0098772,GO:0120036,GO:0120039,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.0000000001426 70.0
HFD2_k127_8318_3 SWIM zinc finger - - - 0.00005027 53.0
HFD2_k127_8324168_0 PFAM Mo-dependent nitrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000008018 231.0
HFD2_k127_8324168_1 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000007452 111.0
HFD2_k127_8324168_2 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000008234 106.0
HFD2_k127_8325062_0 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009487 389.0
HFD2_k127_8327041_0 Protein involved in outer membrane biogenesis - - - 0.000000000000000000000001718 112.0
HFD2_k127_8327091_0 Kelch motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004603 256.0
HFD2_k127_8327091_1 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000000003741 105.0
HFD2_k127_8329820_0 Permease family K06901 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006856 361.0
HFD2_k127_8334718_0 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000004217 213.0
HFD2_k127_8334718_1 - - - - 0.0000000000001469 70.0
HFD2_k127_8336651_0 Protein kinase domain - - - 8.324e-223 707.0
HFD2_k127_8336651_1 protein related to plant photosystem II stability assembly factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000003344 233.0
HFD2_k127_8336651_2 Peptidase C13 family - - - 0.0000000000000000000000000000001891 129.0
HFD2_k127_8341045_0 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001379 258.0
HFD2_k127_834240_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 321.0
HFD2_k127_834240_1 Domain present in PSD-95, Dlg, and ZO-1/2. K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 291.0
HFD2_k127_834240_2 Sh3 type 3 domain protein K01185,K07184,K07260 - 3.2.1.17,3.4.17.14 0.0000000000000000000000000000000000222 148.0
HFD2_k127_8346473_0 PFAM regulator of chromosome condensation, RCC1 - - - 0.00000000000000000000000000000000000000000000000001173 195.0
HFD2_k127_8346473_1 - - - - 0.00000000000000000000000000000000000000009257 167.0
HFD2_k127_8346473_2 Sel1-like repeats. K07126 - - 0.000000003866 66.0
HFD2_k127_83508_0 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 419.0
HFD2_k127_83508_2 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.0000000000000000000000000000000000000000001665 162.0
HFD2_k127_83508_3 - - - - 0.000000001981 68.0
HFD2_k127_8351926_0 Surface antigen - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004408 537.0
HFD2_k127_8351926_1 PFAM Dockerin type - - - 0.0000000000000000000000000000000000000000000003094 187.0
HFD2_k127_8351926_2 Belongs to the ompA family K03286 - - 0.00000000006624 73.0
HFD2_k127_8359302_0 cytochrome C peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000003035 239.0
HFD2_k127_8359302_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000001844 209.0
HFD2_k127_8359302_2 FR47-like protein K03789 - 2.3.1.128 0.00000000000000000000000008972 118.0
HFD2_k127_8360543_0 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 321.0
HFD2_k127_8369700_0 Mycolic acid cyclopropane synthetase K00574,K20238 - 2.1.1.317,2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004639 426.0
HFD2_k127_8369700_1 Carbon-nitrogen hydrolase - - - 0.000000000000000000000000000000000000000000000000000000397 207.0
HFD2_k127_8369700_2 metal cluster binding K06940 - - 0.00000000000000000000000000000000000000000000003988 180.0
HFD2_k127_837141_0 SMP-30/Gluconolaconase/LRE-like region - - - 0.00000000000000000000000000000000000000000001124 171.0
HFD2_k127_8373372_0 Histidine kinase - - - 0.000000000000000000000000000000000000001193 159.0
HFD2_k127_8373372_1 HEAT repeats - - - 0.000000000000000000000000000000001298 142.0
HFD2_k127_8373372_2 nuclease activity K07460 - - 0.000000000000000004952 88.0
HFD2_k127_8377306_0 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 527.0
HFD2_k127_8383003_0 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 547.0
HFD2_k127_8383003_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000796 322.0
HFD2_k127_8387084_0 NLP P60 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 304.0
HFD2_k127_8387084_1 oxidoreductase activity K07114 - - 0.000000000000000000000000000000000000000000000000000000001959 218.0
HFD2_k127_8387084_2 phosphorelay signal transduction system K01768,K10941,K11894 - 4.6.1.1 0.00000000000000000002889 93.0
HFD2_k127_8405069_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821,K09251 - 2.6.1.11,2.6.1.17,2.6.1.82 0.0000000000000000000000000000000000000000000000000000000000000000000000000333 267.0
HFD2_k127_8408331_0 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004142 486.0
HFD2_k127_8408331_1 Dehydrogenase K00030,K00052 - 1.1.1.41,1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007514 309.0
HFD2_k127_8408424_0 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000005164 228.0
HFD2_k127_8408424_1 histone H2A K63-linked ubiquitination K21397 - - 0.0001671 49.0
HFD2_k127_841292_0 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 524.0
HFD2_k127_8413657_0 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 386.0
HFD2_k127_8413657_1 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000003256 168.0
HFD2_k127_8413657_2 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000009521 66.0
HFD2_k127_8426835_0 Proposed nucleic acid binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004651 417.0
HFD2_k127_8426835_1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0004039 53.0
HFD2_k127_8428798_0 Protein of unknown function (DUF3829) - - - 0.0000000000000000000000000000006883 136.0
HFD2_k127_8428798_1 SurA N-terminal domain K03771 - 5.2.1.8 0.00000000000000000008567 96.0
HFD2_k127_8430085_0 FtsX-like permease family K02004 - - 7.489e-211 680.0
HFD2_k127_8430085_1 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 336.0
HFD2_k127_8430085_2 TIGRFAM efflux transporter, RND family, MFP subunit K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003306 341.0
HFD2_k127_8430085_3 Kelch motif - - - 0.0000000000000000000000000000001693 138.0
HFD2_k127_8430085_4 Histidine kinase - - - 0.00000000000000000000000539 104.0
HFD2_k127_8430771_0 PFAM asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 334.0
HFD2_k127_8430771_1 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000005649 179.0
HFD2_k127_8437540_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 574.0
HFD2_k127_8442901_0 Aldo Keto reductase K05275 - 1.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 464.0
HFD2_k127_8442901_1 LysR substrate binding domain K18297 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007098 421.0
HFD2_k127_8442901_10 - - - - 0.000000000005865 77.0
HFD2_k127_8442901_11 Uncharacterized protein conserved in bacteria (DUF2330) - - - 0.0000000001637 73.0
HFD2_k127_8442901_12 Pentapeptide repeats (9 copies) - - - 0.00000375 55.0
HFD2_k127_8442901_2 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004977 346.0
HFD2_k127_8442901_3 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000003998 232.0
HFD2_k127_8442901_4 Serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000006874 180.0
HFD2_k127_8442901_5 - - - - 0.0000000000000000000000000000000007001 141.0
HFD2_k127_8442901_6 Cytochrome c - - - 0.000000000000000000000001465 115.0
HFD2_k127_8442901_7 - - - - 0.0000000000000000000009911 102.0
HFD2_k127_8442901_8 Belongs to the BolA IbaG family - - - 0.000000000000000000004305 94.0
HFD2_k127_8442901_9 Transcriptional regulator - - - 0.000000000000001215 83.0
HFD2_k127_8450488_0 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 335.0
HFD2_k127_8450488_1 FHA domain - - - 0.0000000000000000000000009949 119.0
HFD2_k127_8450488_2 long-chain fatty acid transport protein - - - 0.00001977 57.0
HFD2_k127_8454095_0 - - - - 0.0000000000001113 84.0
HFD2_k127_8461708_0 Involved in arsenical resistance. Thought to form the channel of an arsenite pump K03893 - - 0.00000000000000000000000000000000000000000002072 178.0
HFD2_k127_8464691_0 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000001339 254.0
HFD2_k127_8464691_1 HMGL-like K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000001289 166.0
HFD2_k127_8464691_2 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000000000000000001122 160.0
HFD2_k127_8464691_3 PFAM PEBP family protein K06910 - - 0.000000000000000000000000000000000001187 145.0
HFD2_k127_8464691_4 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000001668 119.0
HFD2_k127_8469758_0 transcription factor binding K02584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 382.0
HFD2_k127_8474774_0 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006847 354.0
HFD2_k127_8474774_1 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005379 312.0
HFD2_k127_8474774_2 PFAM regulator of chromosome condensation, RCC1 - - - 0.0000000000000000000000000000000000000001726 168.0
HFD2_k127_8478242_0 Part of the ABC transporter complex XylFGH involved in xylose import. Responsible for energy coupling to the transport system K10545 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006237 401.0
HFD2_k127_8478242_1 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000002977 190.0
HFD2_k127_8479835_0 4 iron, 4 sulfur cluster binding - - - 7.576e-201 639.0
HFD2_k127_8479835_1 Sel1-like repeats. K07126 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 428.0
HFD2_k127_8481961_0 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 421.0
HFD2_k127_8492107_0 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001005 277.0
HFD2_k127_8492107_1 Molecular chaperone. Has ATPase activity K04079 - - 0.00000000001744 64.0
HFD2_k127_8492107_2 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 0.00000008585 54.0
HFD2_k127_8492107_3 Large extracellular alpha-helical protein - - - 0.000007214 59.0
HFD2_k127_849505_0 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 387.0
HFD2_k127_849505_1 phosphorelay signal transduction system K10941,K21405 - - 0.000000000000000000000000000000000000000000000000000000000000000003407 230.0
HFD2_k127_849505_2 PFAM Cold-shock protein, DNA-binding - - - 0.00000000000000000000000001561 112.0
HFD2_k127_8495630_0 cell envelope organization K05807,K08309 - - 0.000000000000000000000000000001378 135.0
HFD2_k127_8495630_1 Pilus assembly protein, PilP - - - 0.00000000000000000007705 98.0
HFD2_k127_85107_0 Family membership K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006016 286.0
HFD2_k127_85107_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000008047 153.0
HFD2_k127_8512901_0 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000133 245.0
HFD2_k127_8512901_1 peptidyl-tyrosine sulfation - - - 0.000000007132 66.0
HFD2_k127_8518340_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1122.0
HFD2_k127_8518340_1 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 445.0
HFD2_k127_8518340_2 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 312.0
HFD2_k127_8518340_3 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000001962 218.0
HFD2_k127_8518340_5 peptidyl-tyrosine sulfation - - - 0.00006929 55.0
HFD2_k127_8518822_0 Dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009291 505.0
HFD2_k127_8519807_0 - - - - 0.000000001645 69.0
HFD2_k127_8519807_1 - - - - 0.00006006 55.0
HFD2_k127_8520699_0 peptidyl-tyrosine sulfation - - - 0.00000000000001606 85.0
HFD2_k127_8531577_0 Metal dependent phosphohydrolases with conserved 'HD' motif. K00970 - 2.7.7.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 381.0
HFD2_k127_8533816_0 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000002527 235.0
HFD2_k127_8533816_1 Protein kinase domain - - - 0.0000000000000000000000000000000000005935 145.0
HFD2_k127_8536835_0 WD40 repeat-like protein - - - 0.00001261 59.0
HFD2_k127_8555158_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family - - - 0.00000000000000000000000000000001645 136.0
HFD2_k127_8555158_1 helix_turn_helix, Lux Regulon - - - 0.000000389 53.0
HFD2_k127_8555158_2 Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine K07008 GO:0000096,GO:0000097,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006518,GO:0006520,GO:0006547,GO:0006548,GO:0006575,GO:0006577,GO:0006578,GO:0006725,GO:0006749,GO:0006751,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016020,GO:0016053,GO:0016054,GO:0019439,GO:0019752,GO:0032991,GO:0034641,GO:0042219,GO:0042398,GO:0043171,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0051186,GO:0051187,GO:0052698,GO:0052699,GO:0052701,GO:0052703,GO:0052704,GO:0052708,GO:0052803,GO:0052805,GO:0061672,GO:0071704,GO:0071944,GO:0097164,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902494,GO:1905368 3.5.1.118 0.000002833 58.0
HFD2_k127_8561281_0 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family K05548 - - 0.0000000000000000000000000000000000000000000000000000000000000000001255 235.0
HFD2_k127_8561896_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1350.0
HFD2_k127_8561896_1 Aldo/keto reductase family K05275 - 1.1.1.65 0.0000000000000000000000000000000000000000000000000000000000001916 216.0
HFD2_k127_8571314_0 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003924 442.0
HFD2_k127_8580954_0 HEAT repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002562 273.0
HFD2_k127_8581668_1 - - - - 0.000000000000875 79.0
HFD2_k127_8588596_1 membrane K08989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006296 279.0
HFD2_k127_8590903_0 PEGA domain - - - 0.00000000000000000000000000000000000000000000000000000009362 207.0
HFD2_k127_8590903_1 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000126 71.0
HFD2_k127_8591614_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 540.0
HFD2_k127_8591614_1 Belongs to the ompA family K03286 - - 0.000000000000000000000000000000000007478 149.0
HFD2_k127_8593560_0 tRNA cytidylyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004445 374.0
HFD2_k127_8593560_1 ATPase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003384 316.0
HFD2_k127_8593560_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000003446 219.0
HFD2_k127_8593560_3 Zn peptidase - - - 0.000000000000000000000000000000000000000000000000000000000386 209.0
HFD2_k127_8593560_4 - - - - 0.0000000000000000000000000000000000007907 147.0
HFD2_k127_8593560_5 proteolysis - - - 0.00000000000000004523 85.0
HFD2_k127_8593560_6 Helix-turn-helix domain protein - - - 0.0000001793 57.0
HFD2_k127_8603359_0 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000516 448.0
HFD2_k127_8603359_1 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 396.0
HFD2_k127_8603359_2 Transketolase, pyrimidine binding domain K00162,K21417 - 1.2.4.1 0.00000000000000000000000000000000002246 138.0
HFD2_k127_8604609_0 long-chain fatty acid transport protein K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 366.0
HFD2_k127_8604609_1 long-chain fatty acid transport protein K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008017 347.0
HFD2_k127_8615065_0 Family membership K08884 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 318.0
HFD2_k127_8615065_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000001571 220.0
HFD2_k127_8615065_2 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.00000000000000000000000000000000000000000001721 169.0
HFD2_k127_8615065_3 amine dehydrogenase activity - - - 0.00000000000000000000000002088 124.0
HFD2_k127_8615772_0 Glutathione S-transferase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000006177 196.0
HFD2_k127_8615772_1 metallophosphoesterase K07096 - - 0.00000000000000000000000000000000000001598 145.0
HFD2_k127_8615772_2 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000002833 151.0
HFD2_k127_8616390_0 PilZ domain - - - 0.0000000000000008141 87.0
HFD2_k127_8616390_1 Periplasmic or secreted lipoprotein - - - 0.000000000115 73.0
HFD2_k127_8617525_0 Multicopper oxidase K22348 - 1.16.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 518.0
HFD2_k127_8617525_1 Outer membrane efflux protein K15725 - - 0.00000000000000000000000000000000000000000000007439 174.0
HFD2_k127_8619579_0 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000004773 188.0
HFD2_k127_8619579_1 - - - - 0.0000000000000000000000000000000000000000001896 162.0
HFD2_k127_8619579_2 - - - - 0.00000000001876 74.0
HFD2_k127_8619579_3 Glycosyl hydrolases family 2 - - - 0.000000005 67.0
HFD2_k127_8619579_4 Acts as a magnesium transporter K06213 - - 0.000000237 53.0
HFD2_k127_8621607_0 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000698 271.0
HFD2_k127_8621607_1 Sigma-54 interaction domain K02584 - - 0.0000000000008332 80.0
HFD2_k127_8621607_2 Thiamine pyrophosphate enzyme, central domain K00156,K00158 - 1.2.3.3,1.2.5.1 0.0000003592 53.0
HFD2_k127_8623249_0 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000001873 121.0
HFD2_k127_8623249_1 calcium ion binding K06254 - - 0.0000008848 60.0
HFD2_k127_8626370_0 Coenzyme A transferase K01029 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004486 367.0
HFD2_k127_8626370_1 PFAM Coenzyme A transferase K01027,K01028,K01031,K01034 - 2.8.3.5,2.8.3.6,2.8.3.8,2.8.3.9 0.000001026 50.0
HFD2_k127_8629192_0 Serine protease with a broad substrate specificity K13276,K17734 - - 0.00000000000001479 88.0
HFD2_k127_8630072_0 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006587 528.0
HFD2_k127_8634103_0 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002063 300.0
HFD2_k127_8634103_1 protein hemolysin III K11068 - - 0.00000000000000000000000000000000000000000000002317 179.0
HFD2_k127_8634103_2 TIGRFAM RHS repeat-associated core domain - - - 0.000000000001521 77.0
HFD2_k127_8636682_0 LytTr DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004742 296.0
HFD2_k127_8636682_1 Histidine kinase K02478 - 2.7.13.3 0.0000000000000000000000000000000000000000001229 165.0
HFD2_k127_8638118_0 Transposase - - - 0.00000000000000000000003144 114.0
HFD2_k127_8639966_0 sulfuric ester hydrolase activity K03760,K19353 - 2.7.8.43 0.00000000000000000000000000000000000000000079 173.0
HFD2_k127_8639966_1 - - - - 0.00000000000000000000000006446 116.0
HFD2_k127_8645767_1 - - - - 0.0000000000000000000000000000000000000088 152.0
HFD2_k127_8653312_0 ABC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007321 436.0
HFD2_k127_8653312_1 Belongs to the 5'-nucleotidase family K08693 - 3.1.3.5,3.1.3.6,3.1.4.16 0.00000000000000000001176 105.0
HFD2_k127_8656862_0 phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001546 277.0
HFD2_k127_8656862_1 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000000000000375 136.0
HFD2_k127_8656862_2 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000001123 128.0
HFD2_k127_8656862_3 iron ion homeostasis K04758 - - 0.00000000003924 68.0
HFD2_k127_8658426_0 COG2755 Lysophospholipase L1 and related esterases - - - 0.000000000000000000000000000004973 132.0
HFD2_k127_8658426_1 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.00000000000000000001484 101.0
HFD2_k127_8660256_0 acyl-CoA dehydrogenase K09456,K20035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 547.0
HFD2_k127_8660256_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004338 386.0
HFD2_k127_8660256_2 DnaJ molecular chaperone homology domain - - - 0.0000000000000000000000000005279 124.0
HFD2_k127_8660256_3 - - - - 0.0000001851 61.0
HFD2_k127_8660256_4 DnaJ molecular chaperone homology domain - - - 0.000001448 60.0
HFD2_k127_8664539_0 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000000000008775 196.0
HFD2_k127_8664539_1 DNA-binding transcription factor activity K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000249 155.0
HFD2_k127_8664539_2 bacterial-type flagellum-dependent cell motility - - - 0.00001082 53.0
HFD2_k127_8664539_3 OsmC-like protein K04063 - - 0.00001749 48.0
HFD2_k127_8676832_0 pfkB family carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004308 381.0
HFD2_k127_8676832_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 355.0
HFD2_k127_8677249_0 Hydrogenase formation hypA family K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004122 406.0
HFD2_k127_8677249_1 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000008006 219.0
HFD2_k127_8677249_2 AIR synthase related protein, C-terminal domain K04655 - - 0.00000000000000000000007509 104.0
HFD2_k127_8683582_0 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 358.0
HFD2_k127_8683582_1 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003494 270.0
HFD2_k127_8683582_2 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000000000000000000000000000000000000005732 194.0
HFD2_k127_8683582_3 serine-type endopeptidase activity - - - 0.00000000000000000000000003364 123.0
HFD2_k127_8684584_0 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001777 284.0
HFD2_k127_8688505_0 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001598 248.0
HFD2_k127_8688505_1 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000106 175.0
HFD2_k127_8688505_2 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000001599 144.0
HFD2_k127_8688505_3 Fatty acid hydroxylase superfamily - - - 0.00000000000000000000000000000007279 134.0
HFD2_k127_8689356_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008946 609.0
HFD2_k127_8689356_1 succinyl-diaminopimelate desuccinylase K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 427.0
HFD2_k127_8689356_10 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0008169 51.0
HFD2_k127_8689356_2 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 417.0
HFD2_k127_8689356_3 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004684 389.0
HFD2_k127_8689356_4 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000000000000001071 197.0
HFD2_k127_8689356_6 DNA-templated transcription, initiation K03088 - - 0.000000000000007198 83.0
HFD2_k127_8689356_7 depolymerase K03932 - - 0.00000000000004371 83.0
HFD2_k127_8689356_8 nuclear chromosome segregation - - - 0.000002584 54.0
HFD2_k127_8689356_9 zinc-ribbon domain - - - 0.00007083 53.0
HFD2_k127_8690854_0 ArgK protein K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 391.0
HFD2_k127_8690854_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 292.0
HFD2_k127_8690854_2 Serine Threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000001883 141.0
HFD2_k127_8695571_0 protein trimerization - - - 0.0000000000000000000000000000000000001059 156.0
HFD2_k127_8695571_1 Nodulation protein S (NodS) - - - 0.00000000000000000000000000001498 128.0
HFD2_k127_8695571_2 amine dehydrogenase activity K12132 - 2.7.11.1 0.00000001315 66.0
HFD2_k127_8697472_0 Encapsulating protein for peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 314.0
HFD2_k127_86977_0 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 3.588e-200 644.0
HFD2_k127_86977_1 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 409.0
HFD2_k127_86977_2 desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003815 358.0
HFD2_k127_86977_3 RF-1 domain K15034 - - 0.00000000000000000000000000000000000000001323 159.0
HFD2_k127_86977_4 high-affinity sulfate:proton symporter activity K06203 GO:0000096,GO:0000097,GO:0000103,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0008150,GO:0008152,GO:0008271,GO:0008272,GO:0008324,GO:0008509,GO:0008512,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009675,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015103,GO:0015116,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015296,GO:0015318,GO:0015672,GO:0015698,GO:0016020,GO:0016021,GO:0016053,GO:0019344,GO:0019752,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044425,GO:0044459,GO:0044464,GO:0046394,GO:0051179,GO:0051234,GO:0055085,GO:0071704,GO:0071944,GO:0072348,GO:0098655,GO:0098656,GO:0098660,GO:0098661,GO:0098662,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901682,GO:1902358,GO:1902600 - 0.0000000000000000000000000000000000000002814 160.0
HFD2_k127_86977_7 YndJ-like protein - - - 0.000000000007073 77.0
HFD2_k127_869776_0 PFAM amidohydrolase K01464 - 3.5.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009858 589.0
HFD2_k127_869776_1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001795 282.0
HFD2_k127_869776_2 cellulose binding - - - 0.0000000000000000005551 98.0
HFD2_k127_8702572_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 1.016e-252 789.0
HFD2_k127_8702572_1 Family membership K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000008005 197.0
HFD2_k127_8702572_2 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.000000000000000000000000000000000000005518 147.0
HFD2_k127_8703332_0 alpha beta - - - 0.00000000000000000000000000000000000000000000000000000000000000000001855 238.0
HFD2_k127_8705121_0 COG0618 Exopolyphosphatase-related proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 353.0
HFD2_k127_8705121_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000006309 88.0
HFD2_k127_8705121_2 Histidine triad domain protein K02503 - - 0.00000003555 61.0
HFD2_k127_8705121_3 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.000009069 47.0
HFD2_k127_8706225_0 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001182 256.0
HFD2_k127_8706225_1 zinc-ribbon domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000005395 260.0
HFD2_k127_8706225_3 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000001975 188.0
HFD2_k127_8706225_4 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000000000000000000001876 173.0
HFD2_k127_8713380_0 small GTP-binding protein K02355 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 477.0
HFD2_k127_8713380_1 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.000000000000000000000000000000000116 134.0
HFD2_k127_8714613_0 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004318 523.0
HFD2_k127_8714613_1 PilZ domain K02676 - - 0.000000000000000000000000000000002291 136.0
HFD2_k127_8718587_0 protein with protein kinase and helix-hairpin-helix DNA-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007137 327.0
HFD2_k127_8718587_1 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.0000000000004431 70.0
HFD2_k127_8718587_2 Protein phosphatase 2C - - - 0.000000003505 66.0
HFD2_k127_8721702_0 Forkhead associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 527.0
HFD2_k127_8721736_0 DNA-templated transcription, initiation K03088,K11333 - 1.3.7.14,1.3.7.15 0.0000000000000000000000000000000000000000000000152 177.0
HFD2_k127_8721736_1 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000001235 167.0
HFD2_k127_8723000_0 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 461.0
HFD2_k127_8723000_1 - - - - 0.0000000000000000000000000000000000000000000000000337 196.0
HFD2_k127_8726389_0 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000007702 218.0
HFD2_k127_8726389_1 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000002553 211.0
HFD2_k127_8726389_2 Family membership K08884 - 2.7.11.1 0.00000000000000000000000006859 118.0
HFD2_k127_8729621_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 541.0
HFD2_k127_8729621_1 PFAM Formylglycine-generating sulfatase enzyme K20333 - - 0.000000000000000000000000000000000009329 143.0
HFD2_k127_8732964_0 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000005207 192.0
HFD2_k127_8732964_1 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.0000000000000000000000000000000000000008583 162.0
HFD2_k127_8732964_3 transcriptional regulator - - - 0.000000000000000002273 95.0
HFD2_k127_8732964_4 Role in flagellar biosynthesis K02421 - - 0.000000001026 64.0
HFD2_k127_8733301_0 Carboxyl transferase domain K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 533.0
HFD2_k127_8733301_1 Family membership K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000002366 165.0
HFD2_k127_8733817_0 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000469 395.0
HFD2_k127_8733817_1 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000001445 270.0
HFD2_k127_8741838_0 AcrB/AcrD/AcrF family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 355.0
HFD2_k127_8741838_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000001349 121.0
HFD2_k127_8742180_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 7.251e-304 951.0
HFD2_k127_8743633_0 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000004966 211.0
HFD2_k127_8743633_1 PLD-like domain - - - 0.000000000000000000000000000000000000000000006529 184.0
HFD2_k127_8743633_2 LysR substrate binding domain - - - 0.000000000000000001366 93.0
HFD2_k127_8749147_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000003801 228.0
HFD2_k127_8749147_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000009282 192.0
HFD2_k127_8752081_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 329.0
HFD2_k127_8752749_0 Type II and III secretion system protein K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 456.0
HFD2_k127_8752749_1 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001471 279.0
HFD2_k127_8756576_0 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000002252 173.0
HFD2_k127_8756576_1 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000000004449 177.0
HFD2_k127_8756576_2 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000009523 147.0
HFD2_k127_880438_0 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000001404 168.0
HFD2_k127_881155_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009874 282.0
HFD2_k127_881155_1 Transcription factor zinc-finger - - - 0.0000000003156 68.0
HFD2_k127_882910_0 GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000055 387.0
HFD2_k127_882910_1 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.0000000000000000000000000005137 123.0
HFD2_k127_895934_1 HEAT repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 447.0
HFD2_k127_905187_0 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K09461 - 1.14.13.40 1.389e-287 901.0
HFD2_k127_906930_0 PFAM FAD linked oxidase domain protein K00803 - 2.5.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 443.0
HFD2_k127_906930_1 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000002223 238.0
HFD2_k127_915138_0 - - - - 0.00000000000000000000000015 123.0
HFD2_k127_915138_1 Uncharacterised conserved protein (DUF2228) - - - 0.00000000000000000219 100.0
HFD2_k127_916572_0 enterobactin catabolic process K07214 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0008150,GO:0008152,GO:0008849,GO:0009056,GO:0009237,GO:0009238,GO:0009712,GO:0009987,GO:0016787,GO:0016788,GO:0018958,GO:0019336,GO:0019439,GO:0019614,GO:0019748,GO:0044237,GO:0044248,GO:0044424,GO:0044464,GO:0046214,GO:0046215,GO:0046483,GO:0046700,GO:0051186,GO:0051187,GO:0071704,GO:0090487,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616 - 0.0000000000000000000000000000000000000000000000000000000000001475 222.0
HFD2_k127_916572_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000005799 153.0
HFD2_k127_916572_2 Monogalactosyldiacylglycerol (MGDG) synthase K03429 - 2.4.1.315 0.0000000000000000000000000000000002938 146.0
HFD2_k127_917391_0 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000396 316.0
HFD2_k127_91873_0 - - - - 0.00000000000000002434 92.0
HFD2_k127_91873_1 NosL - - - 0.000000000003858 78.0
HFD2_k127_920483_0 Peptidase family M1 domain - - - 0.0000000000000000000000000000000000000164 151.0
HFD2_k127_920483_1 Tetratricopeptide repeats - - - 0.00000000000000000000000000000000002304 146.0
HFD2_k127_932954_0 Molydopterin dinucleotide binding domain K00123,K00372 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 334.0
HFD2_k127_932954_1 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000001128 158.0
HFD2_k127_935986_0 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002127 270.0
HFD2_k127_935986_1 FHA domain - - - 0.00004813 55.0
HFD2_k127_937046_0 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003127 419.0
HFD2_k127_937046_1 Protein of unknown function (DUF2505) - - - 0.000000000000000000000000000000000000000000001261 171.0
HFD2_k127_937046_2 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000000000000000000000000002057 160.0
HFD2_k127_937046_3 PhoD-like phosphatase K01113 - 3.1.3.1 0.00000000000000000000005048 110.0
HFD2_k127_937371_0 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000001463 158.0
HFD2_k127_937371_1 serine-type endopeptidase activity - - - 0.000002829 55.0
HFD2_k127_939309_0 Multicopper K04753 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 443.0
HFD2_k127_939309_1 Multicopper K04753 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001313 265.0
HFD2_k127_943383_0 ABC transporter, ATP-binding protein K01990 - - 0.000003296 50.0
HFD2_k127_950388_0 4Fe-4S binding domain - - - 8.068e-307 957.0
HFD2_k127_950388_1 phosphate ion binding - - - 0.0000001968 55.0
HFD2_k127_950415_0 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000116 208.0
HFD2_k127_950415_1 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.00000000000000000000021 108.0
HFD2_k127_950992_0 cytochrome C peroxidase - - - 0.00000000000000000000000000000000000000000000007369 180.0
HFD2_k127_95151_0 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K02805 GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005975,GO:0005976,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009246,GO:0009987,GO:0016051,GO:0016740,GO:0016769,GO:0019180,GO:0019842,GO:0030170,GO:0033692,GO:0034637,GO:0034645,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046378,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901135,GO:1901137,GO:1901363,GO:1901576 2.6.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007483 511.0
HFD2_k127_95151_1 - - - - 0.00000000000000000000000000000001469 145.0
HFD2_k127_95151_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000009958 104.0
HFD2_k127_95151_3 fad dependent oxidoreductase K03153 - 1.4.3.19 0.000000000001043 72.0
HFD2_k127_95151_4 - - - - 0.000001248 57.0
HFD2_k127_959450_0 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000086 186.0
HFD2_k127_959450_1 PFAM regulatory protein TetR K13770,K19736 - - 0.00000000000000000000000000000000000008814 149.0
HFD2_k127_959450_2 KR domain - - - 0.00000003237 58.0
HFD2_k127_972376_0 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 391.0
HFD2_k127_972376_1 aminopeptidase activity K19689 - - 0.0000000000000000000005701 108.0
HFD2_k127_974606_0 Domain of unknown function (DUF1998) K06877 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008041 567.0
HFD2_k127_974606_1 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000000000003325 196.0
HFD2_k127_974606_2 Cytochrome c - - - 0.000000000000002217 83.0
HFD2_k127_984742_0 Integral membrane protein TerC family K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002086 276.0
HFD2_k127_984742_1 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.000000000000000000000001907 104.0
HFD2_k127_984742_2 TIGRFAM Trehalose synthase K05343 - 3.2.1.1,5.4.99.16 0.0000000003883 64.0
HFD2_k127_984828_0 domain protein - - - 0.0000000000000000000000000000000000000000000001183 183.0
HFD2_k127_984828_1 - - - - 0.0000000000000000001837 100.0
HFD2_k127_984828_2 GMC oxidoreductase K03333 - 1.1.3.6 0.0000000000000002294 86.0
HFD2_k127_992000_0 asparaginyl-tRNA synthetase K01893 - 6.1.1.22 4.947e-202 638.0
HFD2_k127_992000_1 Protein of unknown function (DUF1684) K09164 - - 0.000000000000000000000000000000000000000000000000000006926 200.0
HFD2_k127_992000_2 Trypsin-like serine protease - - - 0.000004857 57.0
HFD2_k127_994852_0 WGR domain protein - - - 0.00000000000000000000000000000000000000004494 164.0
HFD2_k127_994852_1 histone H2A K63-linked ubiquitination K08884,K11894 - 2.7.11.1 0.00001596 55.0
HFD2_k127_996100_0 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000002574 234.0
HFD2_k127_996100_1 - - - - 0.000000000000000000000000000000000000000000000000000000000001588 224.0
HFD2_k127_996100_2 Forkhead associated domain - - - 0.000001378 53.0
HFD2_k127_998524_0 Domain of unknown function (DUF2520) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009094 263.0
HFD2_k127_998524_1 Sigma-54 interaction domain K10941 - - 0.0000000000000001559 93.0
HFD2_k127_998759_0 C-terminal domain of tail specific protease (DUF3340) K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000003801 241.0