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Overview

ID MAG01662
Name HFD2_bin.54
Sample SMP0044
Taxonomy
Kingdom Bacteria
Phylum Chloroflexota
Class UBA6077
Order UBA6077
Family JACCZL01
Genus
Species
Assembly information
Completeness (%) 78.01
Contamination (%) 3.7
GC content (%) 66.0
N50 (bp) 4,456
Genome size (bp) 4,297,757

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3959

Gene name Description KEGG GOs EC E-value Score Sequence
HFD2_k127_1005274_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000369 224.0
HFD2_k127_1005274_1 Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway K15525 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0010125,GO:0010126,GO:0016020,GO:0016137,GO:0016138,GO:0016787,GO:0016810,GO:0016811,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 3.5.1.103 0.00000000000000000000000000000000000000000000000001747 192.0
HFD2_k127_1005274_2 PFAM Haloacid dehalogenase domain protein hydrolase K01101 - 3.1.3.41 0.000000000000000003588 85.0
HFD2_k127_1013678_0 TIGRFAM UTP--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005659 316.0
HFD2_k127_1013678_1 regulation of RNA biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003161 279.0
HFD2_k127_1013678_2 (Rhomboid) family - - - 0.000000000000000000000000000000000000000000000000000000005601 206.0
HFD2_k127_1013678_3 permease - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.000000000000000000000000000000000000000000003223 179.0
HFD2_k127_1013678_4 elongation factor G K02355 - - 0.000000000000000007816 85.0
HFD2_k127_102086_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001368 286.0
HFD2_k127_102086_1 Two component transcriptional regulator, Winged helix family - - - 0.000000000000000000000000000000000000000000000000000000000000000000393 235.0
HFD2_k127_102086_2 metal ion transport K03319 - - 0.00000000000000005414 89.0
HFD2_k127_1021374_0 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007647 342.0
HFD2_k127_1021374_1 Binding-protein-dependent transport system inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006168 307.0
HFD2_k127_1021374_2 Bacterial extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008532 285.0
HFD2_k127_1022746_0 ABC-type Fe3 transport system permease component K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 486.0
HFD2_k127_1022746_1 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008365 439.0
HFD2_k127_1022746_2 ABC transporter K02056,K06400 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 398.0
HFD2_k127_1022746_3 ABC transporter substrate-binding protein PnrA-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002854 255.0
HFD2_k127_1022746_4 ABC-type transport system permease component K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000008449 245.0
HFD2_k127_1022746_5 Branched-chain amino acid transport system / permease component K02057 - - 0.000000000000000000000000000000000000000000000000000000000000003798 228.0
HFD2_k127_1022746_6 Phosphoribosyl transferase domain K07101 - - 0.0000000000000000000000000000000000000000000000000002431 190.0
HFD2_k127_1022746_7 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000000004506 194.0
HFD2_k127_1022746_8 ubiE/COQ5 methyltransferase family K15942 - 2.1.1.288 0.000000000000000000000000000000000000002141 156.0
HFD2_k127_1023976_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 1.864e-307 956.0
HFD2_k127_1023976_1 S-adenosylmethionine synthetase (AdoMet synthetase) K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007323 443.0
HFD2_k127_1023976_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000005414 103.0
HFD2_k127_1023976_3 Putative cyclase - - - 0.00000000000001398 76.0
HFD2_k127_1023976_4 PFAM regulatory protein AsnC Lrp family - - - 0.00000000002129 67.0
HFD2_k127_1032488_0 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 349.0
HFD2_k127_1032488_1 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001419 269.0
HFD2_k127_1032488_2 Psort location CytoplasmicMembrane, score K01992 - - 0.000000000000000000000000000000000000000000000000000000005367 208.0
HFD2_k127_1032488_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - 0.00000000000000000000000000000000000003203 149.0
HFD2_k127_1032488_4 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain - - - 0.0000000000000000000000000000001436 130.0
HFD2_k127_1032488_5 ABC-type uncharacterized transport system K01992 - - 0.000000000000000000000001276 113.0
HFD2_k127_1032488_6 NMT1-like family K02051 - - 0.00000000000000000000004317 111.0
HFD2_k127_1038210_0 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004563 549.0
HFD2_k127_1038210_1 Tetrapyrrole (Corrin/Porphyrin) Methylases K01719,K01749,K02303,K13542,K13543 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107,2.5.1.61,4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 496.0
HFD2_k127_1038210_2 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 462.0
HFD2_k127_1050302_0 Glutamine synthetase, beta-Grasp domain K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 511.0
HFD2_k127_1050302_1 4-phosphoerythronate dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002438 252.0
HFD2_k127_1050302_2 - - - - 0.00000000000000000002953 96.0
HFD2_k127_1063874_0 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.00000000000000000000000000000000000009755 154.0
HFD2_k127_1063874_1 - - - - 0.00000000000000000000000000000005086 138.0
HFD2_k127_1063874_2 LysM domain M23 M37 peptidase domain protein - - - 0.000000000000001272 90.0
HFD2_k127_1072600_0 PFAM ABC transporter K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005275 266.0
HFD2_k127_1072600_1 ABC-type multidrug transport system, permease component - - - 0.00000000000000000000000000000000000000000000000000000000002736 224.0
HFD2_k127_1073616_0 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000153 174.0
HFD2_k127_1076458_0 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 311.0
HFD2_k127_1076458_1 - - - - 0.000000000000000000000000000000000000000000000000009868 187.0
HFD2_k127_1076458_2 PFAM response regulator receiver K07657 - - 0.00000000000000000000000000000000004869 144.0
HFD2_k127_1076458_3 - - - - 0.00000000000000000000000000002475 121.0
HFD2_k127_1077351_0 chitin deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 341.0
HFD2_k127_1077351_1 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 305.0
HFD2_k127_1077351_2 PFAM Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007712 261.0
HFD2_k127_1077351_3 BioY family K03523 - - 0.0000000000000000000000000000000000000000000000000000000001582 211.0
HFD2_k127_1085349_0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000003397 120.0
HFD2_k127_1085349_1 Class II Aldolase and Adducin N-terminal domain - - - 0.0000000000000000000000001064 117.0
HFD2_k127_1089286_0 III protein, CoA-transferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004639 423.0
HFD2_k127_1089286_1 PFAM Enoyl-CoA hydratase isomerase family K01715,K13767 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004811 279.0
HFD2_k127_1089286_2 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000186 208.0
HFD2_k127_1089286_3 protein related to plant photosystem II stability assembly factor - - - 0.000000000000000000000000000002077 137.0
HFD2_k127_1089286_4 NIPSNAP - - - 0.000000000000000000000001523 112.0
HFD2_k127_1089286_5 Belongs to the enoyl-CoA hydratase isomerase family K01692 GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0030312,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575 4.2.1.17 0.00000000000000004328 85.0
HFD2_k127_1090037_0 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003485 269.0
HFD2_k127_1090037_1 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005156 254.0
HFD2_k127_1090720_0 Acetyl-CoA acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000001539 221.0
HFD2_k127_1090720_1 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000003325 191.0
HFD2_k127_1090720_2 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.00000000000000000000000000002692 121.0
HFD2_k127_110083_0 homoserine dehydrogenase NAD-binding K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006844 360.0
HFD2_k127_110083_1 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008959 246.0
HFD2_k127_1123051_0 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K00320 - 1.5.98.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004753 362.0
HFD2_k127_1123051_1 amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 325.0
HFD2_k127_1123051_2 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008524 317.0
HFD2_k127_1123051_3 Antibiotic biosynthesis monooxygenase - - - 0.0000006938 56.0
HFD2_k127_112810_0 Amidohydrolase - - - 0.000000000000000000000000000000000000000000007353 167.0
HFD2_k127_112810_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000001536 176.0
HFD2_k127_112810_2 GTP cyclohydrolase II - - - 0.000000000000000000000000000000000021 143.0
HFD2_k127_1128811_0 CoA binding domain - - - 4.816e-303 937.0
HFD2_k127_1128811_1 metallopeptidase activity K03592 - - 0.0000000000000000000000000000000000000000709 164.0
HFD2_k127_1129295_0 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 434.0
HFD2_k127_1129295_1 PFAM sugar transferase - - - 0.000000000000000000000000000000002903 129.0
HFD2_k127_1129295_2 Lipopolysaccharide biosynthesis protein - - - 0.00000000000000000000000001321 119.0
HFD2_k127_1129655_0 Peptidase family M41 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 476.0
HFD2_k127_1129655_1 Dehydrogenase E1 component K00166 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 305.0
HFD2_k127_1131528_0 Elongation factor G C-terminus K06207 GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840 - 1.179e-219 701.0
HFD2_k127_1131528_1 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 0.000000000000000000000000000000000000000000000000000000000000000002835 237.0
HFD2_k127_1134969_0 Belongs to the glycosyl hydrolase 31 family K01811 - 3.2.1.177 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003356 289.0
HFD2_k127_1134969_1 Hexapeptide repeat of succinyl-transferase - - - 0.00000000000000000000000000000000000000000001011 168.0
HFD2_k127_1152685_0 Terminase-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 325.0
HFD2_k127_1152685_1 Phage portal protein, SPP1 Gp6-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 301.0
HFD2_k127_1152685_3 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.00000000000004751 74.0
HFD2_k127_1165770_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000636 449.0
HFD2_k127_1174144_0 transposition - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007976 332.0
HFD2_k127_1174144_1 transposase activity K07483,K07497 - - 0.0000000000000000000000000000001503 126.0
HFD2_k127_1174144_2 Glycosyl hydrolase family 59 - - - 0.00000000000000000008195 91.0
HFD2_k127_1187231_0 Hypothetical methyltransferase K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004235 321.0
HFD2_k127_1187231_1 glycerol channel activity K21797 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006195 249.0
HFD2_k127_1187231_2 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.00000000000000000000000000000000000000000000003201 175.0
HFD2_k127_1187231_3 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000000000004913 100.0
HFD2_k127_1187231_4 Alpha/beta hydrolase family - - - 0.0003561 48.0
HFD2_k127_1188258_0 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000008675 207.0
HFD2_k127_1188258_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000001299 126.0
HFD2_k127_1190492_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006173 278.0
HFD2_k127_1191112_0 AIR synthase related protein, N-terminal domain K01933,K11788 GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.1,6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 340.0
HFD2_k127_1191112_1 MOSC domain - - - 0.000000000000000000000000000000000000167 147.0
HFD2_k127_1198293_0 Belongs to the transketolase family K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 414.0
HFD2_k127_1201550_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1284.0
HFD2_k127_1201550_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000005887 83.0
HFD2_k127_1225772_0 Na H antiporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 547.0
HFD2_k127_1225772_1 oxidation-reduction process - - - 0.0000000000000000000000000000000000000000000000000001095 193.0
HFD2_k127_1225772_3 - - - - 0.000000000001247 70.0
HFD2_k127_1225772_4 DDE superfamily endonuclease - - - 0.000000002409 68.0
HFD2_k127_122979_0 Gamma-glutamyltranspeptidase K00681 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.3.2.2,3.4.19.13 2.411e-221 698.0
HFD2_k127_122979_1 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008379 496.0
HFD2_k127_122979_2 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002764 244.0
HFD2_k127_122979_3 Alkaline phosphatase family protein K01113 - 3.1.3.1 0.0000000000000000000000000000000000000000002578 175.0
HFD2_k127_1230902_0 ATP phosphoribosyltransferase K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000751 361.0
HFD2_k127_1230902_1 tRNA synthetase class II core domain (G, H, P, S and T) K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009913 362.0
HFD2_k127_1230902_2 Crp-like helix-turn-helix domain K10914 - - 0.00000000000000000000000000000000000000000000000006853 193.0
HFD2_k127_1230902_3 competence protein - - - 0.00000000000000000000000000000000007761 142.0
HFD2_k127_1230902_4 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.0000000005121 64.0
HFD2_k127_1230902_5 Glycosyltransferases involved in cell wall biogenesis-like protein - - - 0.000000003548 70.0
HFD2_k127_1230902_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000008372 64.0
HFD2_k127_1234358_0 Berberine and berberine like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006132 472.0
HFD2_k127_1234358_1 Belongs to the FGGY kinase family K00851 - 2.7.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 438.0
HFD2_k127_1234358_2 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K03929 - - 0.000000000000000000000000000000000000000000000000000000003739 209.0
HFD2_k127_1234358_3 Beta-lactamase - - - 0.000000000000000000000000000000000000000003064 168.0
HFD2_k127_1234358_4 KR domain - - - 0.00000000000000000000000000000004719 137.0
HFD2_k127_1234358_5 Phosphopantetheine attachment site - - - 0.0000000000000000000009324 97.0
HFD2_k127_1234358_6 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.00004357 54.0
HFD2_k127_1243954_0 YCII-related domain K09780 - - 0.0000002084 61.0
HFD2_k127_1254879_0 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005554 256.0
HFD2_k127_1254879_1 Luciferase-like monooxygenase K14733 - 1.14.13.107 0.000000000000000000000000000000000000000000000000000000000000000000001067 239.0
HFD2_k127_1254879_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000004937 223.0
HFD2_k127_1254879_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000002595 205.0
HFD2_k127_1258693_0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005941 449.0
HFD2_k127_1258693_1 Trypsin K08070,K08372 - 1.3.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000311 316.0
HFD2_k127_1269383_0 TIGRFAM Polyketide-type polyunsaturated fatty acid synthase, PfaA - - - 4.281e-242 759.0
HFD2_k127_1269383_1 Acyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009856 355.0
HFD2_k127_1291823_0 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000001292 64.0
HFD2_k127_1293576_0 Purine catabolism regulatory protein-like family K09684 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001121 263.0
HFD2_k127_1296868_0 ACT domain K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000002024 232.0
HFD2_k127_1296868_1 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000374 233.0
HFD2_k127_1316553_0 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000002532 270.0
HFD2_k127_1316553_1 FMN-binding domain protein - - - 0.000001224 55.0
HFD2_k127_1359968_0 RimK-like ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008755 352.0
HFD2_k127_1359968_1 CoA-transferase family III K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003543 350.0
HFD2_k127_1359968_2 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 301.0
HFD2_k127_1359968_3 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000003307 230.0
HFD2_k127_1359968_4 ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000845 152.0
HFD2_k127_1359968_5 Belongs to the enoyl-CoA hydratase isomerase family K15019 - 4.2.1.116 0.000000000000000000000000000000002135 139.0
HFD2_k127_1359968_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000008876 126.0
HFD2_k127_1359968_7 B-1 B cell differentiation K07126,K13582 - - 0.000000000000001355 91.0
HFD2_k127_1359968_8 Putative peptidoglycan binding domain - - - 0.00000000000008926 85.0
HFD2_k127_1359968_9 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000188 61.0
HFD2_k127_1372895_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00647,K09458 - 2.3.1.179,2.3.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 458.0
HFD2_k127_1372895_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 318.0
HFD2_k127_1372895_2 Domain of unknown function DUF108 K06989 - 1.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000433 229.0
HFD2_k127_1372895_3 Transcriptional regulatory protein, C terminal K07776 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000003152 223.0
HFD2_k127_1372895_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000002985 188.0
HFD2_k127_1372895_5 AMP-binding enzyme C-terminal domain K00666 - - 0.00000000000000000000000000007393 121.0
HFD2_k127_1372895_6 Uncharacterized conserved protein (DUF2203) - - - 0.000000000000000000000003522 107.0
HFD2_k127_1373380_0 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001622 291.0
HFD2_k127_1375641_0 NHL repeat - - - 0.0000000000000007035 78.0
HFD2_k127_1376262_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 4.682e-241 765.0
HFD2_k127_1376262_1 Methylenetetrahydrofolate reductase K00297,K00547,K00548 - 1.5.1.20,2.1.1.10,2.1.1.13 1.662e-216 689.0
HFD2_k127_1382560_0 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.00000000000009811 77.0
HFD2_k127_1384354_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 1.802e-279 869.0
HFD2_k127_1384354_1 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000003722 110.0
HFD2_k127_1384354_2 phosphatidate cytidylyltransferase activity K00981 - 2.7.7.41 0.00000000005629 71.0
HFD2_k127_1393986_0 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008625 360.0
HFD2_k127_1393986_1 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008079 333.0
HFD2_k127_1393986_2 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000005282 153.0
HFD2_k127_1393986_3 membrane - - - 0.00000000000000000000002534 111.0
HFD2_k127_1393986_4 probably involved in intracellular septation - - - 0.000000000000979 77.0
HFD2_k127_1393986_5 PFAM LmbE family protein - - - 0.00000000001127 74.0
HFD2_k127_1393986_6 Belongs to the ClpS family K06891 - - 0.0000001562 57.0
HFD2_k127_1439520_0 Protein of unknown function, DUF255 K06888 - - 0.0000000000000000000000000000000000006837 143.0
HFD2_k127_1439520_1 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000005066 141.0
HFD2_k127_1439520_2 PFAM Dimethylmenaquinone methyltransferase - - - 0.000000000000000000000000001891 114.0
HFD2_k127_1447945_0 PFAM GH3 auxin-responsive promoter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 381.0
HFD2_k127_1447945_1 Mandelate racemase muconate lactonizing enzyme K01856,K19802 - 5.1.1.20,5.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000001028 244.0
HFD2_k127_1447945_2 Patatin-like phospholipase K01999,K07001 - - 0.0000000000000000000000000000000000000000000000000000000002643 226.0
HFD2_k127_1447945_3 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000001301 149.0
HFD2_k127_1447945_4 Peptidase family M48 - - - 0.0000000000000000000002552 111.0
HFD2_k127_1447945_5 MMPL family - - - 0.0000000000000000000005257 104.0
HFD2_k127_1447945_6 Transcriptional regulator K10914 - - 0.0000000000000000000141 96.0
HFD2_k127_1447945_7 Forkhead associated domain - - - 0.0000000000000007083 89.0
HFD2_k127_1447945_8 histone H2A K63-linked ubiquitination - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944 - 0.000000000000421 78.0
HFD2_k127_1466099_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 413.0
HFD2_k127_1466099_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K19647 - 1.1.1.291,1.1.1.31 0.000000000000000000000000000000000000000000000000000000000001226 222.0
HFD2_k127_1466099_2 - - - - 0.0000000000000000000000000000001095 136.0
HFD2_k127_1466099_3 RIIalpha, Regulatory subunit portion of type II PKA R-subunit K04739 GO:0000003,GO:0000166,GO:0000226,GO:0000280,GO:0001704,GO:0001707,GO:0001932,GO:0001933,GO:0001934,GO:0002682,GO:0002683,GO:0002694,GO:0002695,GO:0003006,GO:0003008,GO:0003014,GO:0003091,GO:0003674,GO:0004857,GO:0004860,GO:0004862,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005929,GO:0005952,GO:0006355,GO:0006357,GO:0006464,GO:0006468,GO:0006469,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006996,GO:0007010,GO:0007015,GO:0007017,GO:0007049,GO:0007143,GO:0007154,GO:0007162,GO:0007163,GO:0007165,GO:0007267,GO:0007268,GO:0007274,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007308,GO:0007309,GO:0007369,GO:0007389,GO:0007498,GO:0007507,GO:0007591,GO:0007596,GO:0007599,GO:0007610,GO:0007611,GO:0007612,GO:0007613,GO:0007635,GO:0008103,GO:0008150,GO:0008152,GO:0008283,GO:0008285,GO:0008306,GO:0008355,GO:0008603,GO:0009611,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009798,GO:0009887,GO:0009888,GO:0009889,GO:0009892,GO:0009893,GO:0009966,GO:0009968,GO:0009987,GO:0009994,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010562,GO:0010563,GO:0010564,GO:0010604,GO:0010605,GO:0010639,GO:0010646,GO:0010648,GO:0010721,GO:0010927,GO:0010948,GO:0014706,GO:0014855,GO:0016020,GO:0016043,GO:0016310,GO:0016325,GO:0017076,GO:0019207,GO:0019210,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0019887,GO:0019899,GO:0019900,GO:0019901,GO:0019904,GO:0019932,GO:0019933,GO:0019935,GO:0019953,GO:0021700,GO:0022402,GO:0022407,GO:0022408,GO:0022412,GO:0022414,GO:0022607,GO:0023051,GO:0023052,GO:0023057,GO:0030029,GO:0030036,GO:0030104,GO:0030154,GO:0030155,GO:0030234,GO:0030239,GO:0030291,GO:0030551,GO:0030552,GO:0030554,GO:0030951,GO:0030952,GO:0031032,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031399,GO:0031400,GO:0031401,GO:0031588,GO:0031594,GO:0031625,GO:0032147,GO:0032268,GO:0032269,GO:0032270,GO:0032501,GO:0032502,GO:0032504,GO:0032553,GO:0032555,GO:0032559,GO:0032870,GO:0032878,GO:0032944,GO:0032945,GO:0032989,GO:0032991,GO:0033002,GO:0033043,GO:0033673,GO:0033674,GO:0033762,GO:0034199,GO:0034236,GO:0035265,GO:0035556,GO:0036094,GO:0036211,GO:0040007,GO:0040020,GO:0042048,GO:0042060,GO:0042127,GO:0042129,GO:0042130,GO:0042221,GO:0042303,GO:0042325,GO:0042326,GO:0042327,GO:0042493,GO:0042592,GO:0042692,GO:0042802,GO:0042995,GO:0043085,GO:0043086,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043412,GO:0043434,GO:0043549,GO:0043900,GO:0043901,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044389,GO:0044422,GO:0044424,GO:0044425,GO:0044441,GO:0044444,GO:0044459,GO:0044463,GO:0044464,GO:0044703,GO:0044853,GO:0045121,GO:0045202,GO:0045214,GO:0045471,GO:0045595,GO:0045596,GO:0045786,GO:0045835,GO:0045859,GO:0045860,GO:0045936,GO:0045937,GO:0046006,GO:0046007,GO:0046677,GO:0048285,GO:0048332,GO:0048468,GO:0048469,GO:0048477,GO:0048513,GO:0048518,GO:0048519,GO:0048520,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048589,GO:0048598,GO:0048599,GO:0048609,GO:0048646,GO:0048729,GO:0048731,GO:0048738,GO:0048856,GO:0048869,GO:0048871,GO:0048878,GO:0050670,GO:0050672,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050795,GO:0050817,GO:0050863,GO:0050865,GO:0050866,GO:0050868,GO:0050877,GO:0050878,GO:0050890,GO:0050891,GO:0050896,GO:0051018,GO:0051093,GO:0051128,GO:0051129,GO:0051146,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051248,GO:0051249,GO:0051250,GO:0051252,GO:0051321,GO:0051338,GO:0051347,GO:0051348,GO:0051445,GO:0051447,GO:0051704,GO:0051716,GO:0051726,GO:0051783,GO:0051784,GO:0055001,GO:0055002,GO:0055017,GO:0060038,GO:0060255,GO:0060259,GO:0060281,GO:0060283,GO:0060284,GO:0060419,GO:0060537,GO:0061061,GO:0061695,GO:0065007,GO:0065008,GO:0065009,GO:0070663,GO:0070664,GO:0070887,GO:0070925,GO:0071310,GO:0071375,GO:0071377,GO:0071417,GO:0071495,GO:0071704,GO:0071840,GO:0071900,GO:0071901,GO:0071944,GO:0072359,GO:0072375,GO:0080090,GO:0090036,GO:0090038,GO:0097159,GO:0097305,GO:0097367,GO:0097435,GO:0097546,GO:0098589,GO:0098590,GO:0098772,GO:0098805,GO:0098857,GO:0098916,GO:0099536,GO:0099537,GO:0120025,GO:0120038,GO:0140013,GO:1900193,GO:1900194,GO:1901265,GO:1901363,GO:1901564,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902494,GO:1902531,GO:1902532,GO:1902911,GO:1903037,GO:1903038,GO:1903046,GO:1903429,GO:1903430,GO:1903506,GO:1903538,GO:1905879,GO:1905880,GO:1990234,GO:2000112,GO:2000114,GO:2000241,GO:2000242,GO:2000253,GO:2000479,GO:2000480,GO:2001141 - 0.0000000006137 61.0
HFD2_k127_1488685_0 F420-dependent K04091 - 1.14.14.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008125 280.0
HFD2_k127_1488685_1 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.00000000000000000000000000000000000004826 151.0
HFD2_k127_1497570_0 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000634 345.0
HFD2_k127_1497570_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000006452 234.0
HFD2_k127_1497570_2 imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000003392 122.0
HFD2_k127_1499163_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 338.0
HFD2_k127_1499163_1 KR domain - - - 0.0000000000000000000000004361 108.0
HFD2_k127_1510747_0 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000001875 64.0
HFD2_k127_1510747_1 X-Pro dipeptidyl-peptidase (S15 family) K06889 - - 0.00000007311 64.0
HFD2_k127_1530028_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019464,GO:0019752,GO:0032991,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 609.0
HFD2_k127_1530028_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 613.0
HFD2_k127_1530028_2 Belongs to the ABC transporter superfamily K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 506.0
HFD2_k127_1530028_3 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 476.0
HFD2_k127_1530028_4 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 434.0
HFD2_k127_1530028_5 PFAM Glycosyl transferase, family 3 K00756,K00758 - 2.4.2.2,2.4.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 432.0
HFD2_k127_1530028_6 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 314.0
HFD2_k127_1530028_7 PBS lyase HEAT domain protein repeat-containing protein - - - 0.00000000000000000000008485 109.0
HFD2_k127_1533058_0 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000000000000000003782 218.0
HFD2_k127_1533058_1 Transmembrane secretion effector - - - 0.00000000000000000000000000001733 126.0
HFD2_k127_1533058_2 CoA-transferase family III - - - 0.0000000006782 63.0
HFD2_k127_1534647_0 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005489 365.0
HFD2_k127_1534647_1 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.0000000000000000000000000000000000000000000000000000001168 205.0
HFD2_k127_1534647_2 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region - - - 0.000000000000000000000000000003155 132.0
HFD2_k127_1535018_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 1.855e-196 631.0
HFD2_k127_1535018_1 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 441.0
HFD2_k127_1535018_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000005656 269.0
HFD2_k127_1535018_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768,K12132 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0031224,GO:0031226,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.11.1,5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000003392 218.0
HFD2_k127_1535018_4 TIGRFAM glutaredoxin-like domain protein - - - 0.0000000000000000000000000003741 122.0
HFD2_k127_1535018_5 Mechanosensitive ion channel K03442 - - 0.000000000000000000000000107 113.0
HFD2_k127_1535018_6 Thioredoxin domain - - - 0.0000000000000000002972 89.0
HFD2_k127_1541825_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 386.0
HFD2_k127_1541825_1 histidine kinase A domain protein K02484,K07642 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002726 288.0
HFD2_k127_1541825_2 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005626 250.0
HFD2_k127_1553224_0 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000000000001251 132.0
HFD2_k127_1553224_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000001338 136.0
HFD2_k127_1553224_2 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000004202 124.0
HFD2_k127_1553224_3 Binds the 23S rRNA K02909 - - 0.0000000000000000000001143 99.0
HFD2_k127_1553224_4 Bacterial membrane protein YfhO - - - 0.00000005592 58.0
HFD2_k127_1557559_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005997 368.0
HFD2_k127_1562358_0 o-methyltransferase K09846 - 2.1.1.210 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 311.0
HFD2_k127_1576346_0 Myristoyl transferase K02051 - - 0.000000000000000000000000000000000000000325 153.0
HFD2_k127_1576346_1 PFAM pyridoxamine 5'-phosphate K07006 - - 0.000000000002415 73.0
HFD2_k127_1598695_0 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008035 271.0
HFD2_k127_1598695_1 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000049 246.0
HFD2_k127_1598695_2 Belongs to the binding-protein-dependent transport system permease family K01997,K01999 - - 0.000000000000000000000000000000000000000000000000000000002142 213.0
HFD2_k127_1598695_3 Periplasmic binding protein domain K01999 - - 0.000000002415 60.0
HFD2_k127_1603490_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 498.0
HFD2_k127_1603490_1 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000002535 152.0
HFD2_k127_1603490_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000001494 70.0
HFD2_k127_1613071_0 Cellulose synthase K00694 - 2.4.1.12 0.000000000000000000000000000000000000000000000000000000004183 205.0
HFD2_k127_1613071_1 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000007003 168.0
HFD2_k127_1613071_2 - - - - 0.000000000000000005973 93.0
HFD2_k127_1613071_3 EamA-like transporter family - - - 0.0000000004356 64.0
HFD2_k127_16184_0 introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX K03404,K03405 - 6.6.1.1 6.56e-210 666.0
HFD2_k127_16184_1 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 611.0
HFD2_k127_16184_2 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000001159 153.0
HFD2_k127_1629211_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 564.0
HFD2_k127_1629211_1 TIGRFAM 6-phosphogluconate dehydrogenase, decarboxylating K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003299 404.0
HFD2_k127_1629211_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00615,K00616 - 2.2.1.1,2.2.1.2 0.00000001633 57.0
HFD2_k127_1629746_0 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000001934 235.0
HFD2_k127_1629746_1 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000000002654 198.0
HFD2_k127_1629746_2 Putative regulatory protein - - - 0.000003373 51.0
HFD2_k127_1635261_0 Aconitase C-terminal domain K01681 - 4.2.1.3 3.237e-249 786.0
HFD2_k127_1635261_1 MgtE intracellular N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008729 514.0
HFD2_k127_1635261_2 aldo keto reductase - - - 0.0000000000000000000000000000000001188 136.0
HFD2_k127_1635261_3 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.00000000003567 75.0
HFD2_k127_1635261_4 Evidence 4 Homologs of previously reported genes of - - - 0.000000000421 66.0
HFD2_k127_1641556_0 7TM-HD extracellular K07037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000868 421.0
HFD2_k127_1641556_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000741 147.0
HFD2_k127_1641556_2 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K01489,K07042 - 3.5.4.5 0.00000000000000000000000000002667 123.0
HFD2_k127_1641556_3 Yqey-like protein K09117 - - 0.000000000000000000000003739 111.0
HFD2_k127_164172_0 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000004264 212.0
HFD2_k127_164172_1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000001005 72.0
HFD2_k127_164172_2 Tetratricopeptide repeat K09523 - - 0.00000002774 63.0
HFD2_k127_1657252_0 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007062 366.0
HFD2_k127_1657252_1 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004195 323.0
HFD2_k127_1657252_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 310.0
HFD2_k127_1657252_3 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000006365 136.0
HFD2_k127_1665097_0 - - - - 0.0000000000000000000009336 106.0
HFD2_k127_1679489_0 lactoylglutathione lyase activity K05606 - 5.1.99.1 0.0000000000000000000000001348 111.0
HFD2_k127_1679489_1 Bacterial regulatory proteins, lacI family - - - 0.0001711 53.0
HFD2_k127_1686107_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 433.0
HFD2_k127_1686107_1 - - - - 0.00001808 52.0
HFD2_k127_1689526_0 MOSC domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797 322.0
HFD2_k127_1689526_1 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000002453 250.0
HFD2_k127_1689526_2 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000001037 179.0
HFD2_k127_1689526_3 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.0000000000000000000000007204 111.0
HFD2_k127_1697372_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.701e-254 799.0
HFD2_k127_1697372_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000364 398.0
HFD2_k127_1697372_2 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000001636 230.0
HFD2_k127_170729_0 Major facilitator superfamily - - - 0.000000000000000000000000000000000003834 149.0
HFD2_k127_1714463_0 Elongator protein 3, MiaB family, Radical SAM K06937 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004782 402.0
HFD2_k127_1714463_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins - - - 0.000000000000000000000000000000000000000000000000000000000000000005456 233.0
HFD2_k127_1718736_0 - - - - 0.000000000000000000000000000000000112 141.0
HFD2_k127_1718736_1 amine dehydrogenase activity - - - 0.0000000000000005853 78.0
HFD2_k127_1718736_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714,K21062 - 3.5.4.22,4.3.3.7 0.0000000002869 72.0
HFD2_k127_1730953_0 Extradiol ring-cleavage dioxygenase K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000002533 225.0
HFD2_k127_1730953_1 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.000000000000000000000000000000001502 132.0
HFD2_k127_1734443_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 6.865e-257 811.0
HFD2_k127_1734443_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0008479,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 384.0
HFD2_k127_1734443_10 Protein of unknown function (DUF2905) - - - 0.00000000001843 69.0
HFD2_k127_1734443_11 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000002331 66.0
HFD2_k127_1734443_12 - - - - 0.00000001776 67.0
HFD2_k127_1734443_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K00773,K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009314,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0050896,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29,2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 350.0
HFD2_k127_1734443_3 HhH-GPD family K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004165 287.0
HFD2_k127_1734443_4 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002715 281.0
HFD2_k127_1734443_5 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003444 265.0
HFD2_k127_1734443_6 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000003538 264.0
HFD2_k127_1734443_7 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000009913 241.0
HFD2_k127_1734443_8 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000005021 217.0
HFD2_k127_1734443_9 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000003436 104.0
HFD2_k127_1734978_0 PFAM CobN magnesium chelatase K02230 - 6.6.1.2 5.102e-253 807.0
HFD2_k127_1734978_1 PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP K19221 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000425 203.0
HFD2_k127_1734978_2 Phosphate phosphite phosphonate ABC transporter, periplasmic binding protein K02044 - - 0.00000000000000000000002957 106.0
HFD2_k127_1734978_3 Mannose-6-phosphate isomerase - - - 0.00000000000000000001114 98.0
HFD2_k127_1739265_0 phosphopantetheine binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 434.0
HFD2_k127_1739265_1 PFAM Acyl-CoA dehydrogenase, C-terminal domain K06445 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009022 433.0
HFD2_k127_1739265_2 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 301.0
HFD2_k127_1739265_3 Sulfotransferase family - - - 0.00000000000000000000000000000002233 137.0
HFD2_k127_1739265_4 Phosphopantetheine attachment site - - - 0.000000000000000000001282 97.0
HFD2_k127_1741100_0 PFAM extracellular solute-binding protein family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004921 606.0
HFD2_k127_1741100_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000333 410.0
HFD2_k127_1741100_2 Binding-protein-dependent transport system inner membrane component - - - 0.00007484 49.0
HFD2_k127_1744859_0 ATPase activity K03546,K16786,K16787,K19171 - - 0.0000000000000000000000000000000000000000000000000000000004102 214.0
HFD2_k127_1751199_0 catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the K01962,K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 606.0
HFD2_k127_1751199_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008034 520.0
HFD2_k127_1751199_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 497.0
HFD2_k127_1751199_3 Trypsin K08070,K08372 - 1.3.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000009409 261.0
HFD2_k127_1751199_4 Protein of unknown function (DUF3090) - - - 0.00000000000000000000000000000000000001437 150.0
HFD2_k127_1751199_5 Amidohydrolase family - - - 0.00000000001411 69.0
HFD2_k127_1751199_6 - - - - 0.00000000006944 66.0
HFD2_k127_1753993_0 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 372.0
HFD2_k127_1753993_1 Acyl-CoA dehydrogenase, C-terminal domain K22027 - 1.14.13.235 0.000000000000000000000000000000000000000000000000000000000000000000000005209 258.0
HFD2_k127_1753993_2 carboxylic ester hydrolase activity K03928 - 3.1.1.1 0.000000000000000000000000000000000000000000000000000000002419 214.0
HFD2_k127_1757975_0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000005034 249.0
HFD2_k127_1757975_1 PFAM IMP dehydrogenase GMP reductase K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000007947 234.0
HFD2_k127_1757975_2 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000000000000000000000003733 226.0
HFD2_k127_1757975_3 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000006348 223.0
HFD2_k127_1759091_0 Baseplate J-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002795 551.0
HFD2_k127_1759091_1 Phage tail protein (Tail_P2_I) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004363 326.0
HFD2_k127_1759091_2 - - - - 0.0000000000000000000000000000000000000000000000001276 198.0
HFD2_k127_1759091_3 Rhs Element Vgr Protein - - - 0.0000000000000000000000000000000000000000006736 158.0
HFD2_k127_1759091_4 GPW gp25 family protein K06903 - - 0.00000000000000000000000000000000000001118 149.0
HFD2_k127_1767180_0 Belongs to the phosphoglycerate kinase family K00927,K01803 GO:0001871,GO:0002020,GO:0003674,GO:0003824,GO:0004618,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009893,GO:0009986,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019222,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030162,GO:0030193,GO:0030195,GO:0030246,GO:0030247,GO:0030312,GO:0031323,GO:0031325,GO:0032101,GO:0032102,GO:0032268,GO:0032270,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0043532,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050818,GO:0050819,GO:0050878,GO:0051171,GO:0051173,GO:0051186,GO:0051188,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051917,GO:0051919,GO:0055086,GO:0060255,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070613,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0080134,GO:0090407,GO:1900046,GO:1900047,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903034,GO:1903035,GO:1903317,GO:1903319,GO:2001065 2.7.2.3,5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000005298 263.0
HFD2_k127_1767180_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000009357 254.0
HFD2_k127_1767180_2 DNA protecting protein DprA K04096 - - 0.00000000881 60.0
HFD2_k127_1778390_0 Dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000309 271.0
HFD2_k127_1778390_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000195 228.0
HFD2_k127_1783778_0 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000001258 125.0
HFD2_k127_1783778_1 ABC transporter (Permease) K02004 - - 0.0001736 53.0
HFD2_k127_1791251_0 Protein of unknown function, DUF255 K06888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 303.0
HFD2_k127_1802118_0 Hydrolase, NUDIX family - - - 0.000000000000000000000000000001999 128.0
HFD2_k127_1802118_1 major facilitator superfamily K18926 - - 0.00000000000000000000000000516 119.0
HFD2_k127_1802118_2 Major facilitator superfamily - - - 0.0000000007658 61.0
HFD2_k127_1802118_3 Major Facilitator Superfamily - - - 0.00001617 50.0
HFD2_k127_1803499_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000007289 222.0
HFD2_k127_1803499_1 Methyltransferase type 12 - - - 0.00000000000000000000000000000000000000000003076 173.0
HFD2_k127_1803499_2 - - - - 0.0000000001426 70.0
HFD2_k127_1806974_0 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005768 404.0
HFD2_k127_1806974_1 protein kinase activity - - - 0.00000000000000000000000000000000000000000001024 181.0
HFD2_k127_1807658_0 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004342 431.0
HFD2_k127_1807658_1 Amidohydrolase family K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 427.0
HFD2_k127_1807658_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003477 306.0
HFD2_k127_1807658_3 Domain of unknown function (DUF1802) - - - 0.000000000000000000000000000000000000000000000000002224 189.0
HFD2_k127_1807658_4 electron transfer activity K02305,K08738,K17223 - - 0.00000000006121 64.0
HFD2_k127_1828829_0 NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005148 437.0
HFD2_k127_1828829_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 378.0
HFD2_k127_1828829_2 TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 322.0
HFD2_k127_1828829_3 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001695 282.0
HFD2_k127_1828829_4 Sucrose-6F-phosphate phosphohydrolase - - - 0.00000000000000000000000002426 120.0
HFD2_k127_1832523_0 Glycosyltransferases probably involved in cell wall biogenesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 479.0
HFD2_k127_1832523_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008069 325.0
HFD2_k127_1832523_2 Glycosyl hydrolases family 8 K00694 - 2.4.1.12 0.0000000000000000000000000000000000000000000000000000007751 219.0
HFD2_k127_1837625_0 acyl-CoA dehydrogenase K00248,K00249 - 1.3.8.1,1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005871 404.0
HFD2_k127_1837625_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 375.0
HFD2_k127_1837625_2 TIGRFAM methylmalonyl-CoA mutase, large subunit K01848 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002714 333.0
HFD2_k127_1839878_0 AMP-binding enzyme C-terminal domain K00666 - - 5.104e-304 939.0
HFD2_k127_1839878_1 Major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000007851 235.0
HFD2_k127_1839878_2 Putative restriction endonuclease - - - 0.000000000000000000000000000000000000000000000000000005564 197.0
HFD2_k127_1839878_3 Glyoxalase bleomycin resistance protein dioxygenase superfamily protein 19 - - - 0.00000002267 61.0
HFD2_k127_1839878_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K04750 - - 0.0002688 48.0
HFD2_k127_1845497_0 Cytochrome c-type biogenesis protein CcmF C-terminal K02198 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 303.0
HFD2_k127_1845497_1 Cytochrome C assembly protein K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004247 284.0
HFD2_k127_1845497_2 CcmB protein K02194 - - 0.00000000000000000000000000000000000000000000000000000000004458 212.0
HFD2_k127_1845497_3 ATPases associated with a variety of cellular activities K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000002129 184.0
HFD2_k127_1845497_4 Cytochrome c - - - 0.000000000000000000000000000000008607 141.0
HFD2_k127_1845497_5 subunit of a heme lyase K02200 - - 0.00000000000000000000000002624 119.0
HFD2_k127_1845497_6 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000000007106 60.0
HFD2_k127_1849381_0 histidine kinase dimerisation and phosphoacceptor region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003706 280.0
HFD2_k127_1849381_1 aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003247 271.0
HFD2_k127_1849381_2 FAD dependent oxidoreductase K07077 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009217 254.0
HFD2_k127_1849381_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000008231 226.0
HFD2_k127_1849381_4 Sigma-70, region 4 type 2 - - - 0.0000000000000000000000000000000000000000000000000000000000002672 221.0
HFD2_k127_1849569_0 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000000000000000000000000000000000000000000000000000000003547 249.0
HFD2_k127_1849569_1 NIPSNAP - - - 0.000000000000000000000000000000000000000003562 162.0
HFD2_k127_1849569_2 WD40 repeats - - - 0.000000000000000000000000000000000162 137.0
HFD2_k127_1849569_3 - - - - 0.000000000000000000000002957 112.0
HFD2_k127_1853889_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 317.0
HFD2_k127_1853889_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K21566 - - 0.00000000000000000000000000000005329 141.0
HFD2_k127_1853889_2 4Fe-4S binding domain K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000003127 96.0
HFD2_k127_1853889_3 dehalogenase - - - 0.0003668 51.0
HFD2_k127_1871264_0 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 325.0
HFD2_k127_1871264_1 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000008668 127.0
HFD2_k127_1872171_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006149 492.0
HFD2_k127_1872171_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008183 405.0
HFD2_k127_1872171_2 Methylates ribosomal protein L11 K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001591 269.0
HFD2_k127_1872171_3 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008315 268.0
HFD2_k127_1872171_4 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000004845 207.0
HFD2_k127_1872171_5 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000066 160.0
HFD2_k127_1872171_6 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000006414 125.0
HFD2_k127_1872171_7 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000002083 79.0
HFD2_k127_1874629_0 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009218 601.0
HFD2_k127_1874629_1 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000007775 261.0
HFD2_k127_1888200_0 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008479 531.0
HFD2_k127_1888200_1 Domain of unknown function (DUF4157) - - - 0.000000000000000000000000000000005161 141.0
HFD2_k127_1888971_0 Major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 428.0
HFD2_k127_1888971_1 Multidrug transporter K08161 - - 0.000000002863 61.0
HFD2_k127_1888971_2 Penicillin amidase K07116 - 3.5.1.97 0.0005536 46.0
HFD2_k127_18901_0 FMN-dependent dehydrogenase K00101 - 1.1.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 401.0
HFD2_k127_18901_1 - - - - 0.00002194 55.0
HFD2_k127_1900344_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006596 457.0
HFD2_k127_1900344_1 Peptidase M50 K16922 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009873 299.0
HFD2_k127_1900344_2 CoA-transferase family III K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000004577 263.0
HFD2_k127_1900344_3 acyl-CoA transferases carnitine dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000002229 243.0
HFD2_k127_1900344_4 Amidohydrolase K03392 - 4.1.1.45 0.00000000000000000000000000000000000000000000000000000000002001 223.0
HFD2_k127_1900344_5 Alpha beta hydrolase - - - 0.0000000000000000001667 99.0
HFD2_k127_1900344_6 Pfam:AmoA K07120 - - 0.000000000000000001097 92.0
HFD2_k127_1900344_7 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000002164 92.0
HFD2_k127_1900344_8 Transition state regulatory protein AbrB K07120 - - 0.00000000002001 75.0
HFD2_k127_1917024_0 Acyl-CoA dehydrogenase, N-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008859 351.0
HFD2_k127_1917024_1 AMP-binding enzyme C-terminal domain K00666 - - 0.0000000000000000000000000000000000000000000000000000000000008575 218.0
HFD2_k127_1917024_2 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 0.0000000000000000000000000000000000000000000000000000576 189.0
HFD2_k127_191859_0 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 308.0
HFD2_k127_191859_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 302.0
HFD2_k127_191859_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000007557 158.0
HFD2_k127_191859_3 Belongs to the HpcH HpaI aldolase family K01630,K02510 - 4.1.2.20,4.1.2.52 0.000000000000000000000000000000000000006491 155.0
HFD2_k127_191859_4 Amidohydrolase family - - - 0.000000000009097 72.0
HFD2_k127_191862_0 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 538.0
HFD2_k127_191862_1 Transcriptional Regulator of molybdate metabolism, XRE family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006445 388.0
HFD2_k127_191862_2 Binding-protein-dependent transport system inner membrane component K02018,K02046 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000209 263.0
HFD2_k127_191862_3 Bacterial extracellular solute-binding protein K02020 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0040007,GO:0042597,GO:0043167,GO:0043168,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704 - 0.000000000000000000000000000000000000000000000000000000000000000714 229.0
HFD2_k127_1923199_0 ATP-binding region, ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002512 284.0
HFD2_k127_1923199_1 GGDEF domain containing protein - - - 0.00000000000002135 87.0
HFD2_k127_1925048_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 496.0
HFD2_k127_1925048_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005923 368.0
HFD2_k127_1927608_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002637 258.0
HFD2_k127_1927608_1 - - - - 0.00000000000000002607 91.0
HFD2_k127_1937623_0 Elongation factor SelB, winged helix K03833 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004431 601.0
HFD2_k127_1937623_1 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.0000000000000004671 80.0
HFD2_k127_1938167_0 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001584 256.0
HFD2_k127_1943125_0 Pyridine nucleotide-disulphide oxidoreductase K03885,K10716 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003924 442.0
HFD2_k127_1943125_1 CoA-transferase family III K07749 - 2.8.3.16 0.00000000000000000000000000000000004865 137.0
HFD2_k127_1945546_0 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000001451 194.0
HFD2_k127_1945546_1 2-phosphosulfolactate phosphatase activity K05979 GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545 3.1.3.71 0.0000000000000000000000000000000001684 143.0
HFD2_k127_1945546_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000151 96.0
HFD2_k127_1949201_0 PFAM glycosyl transferase group 1 K15521 - 2.4.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 349.0
HFD2_k127_1949201_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000003474 194.0
HFD2_k127_195080_0 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K19244 GO:0000166,GO:0000286,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006522,GO:0006807,GO:0008150,GO:0008152,GO:0009078,GO:0009987,GO:0016491,GO:0016638,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046983,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901605 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000009247 257.0
HFD2_k127_195080_1 SMART PAS domain containing protein - - - 0.00000000000000000000000000000000000002561 164.0
HFD2_k127_1954560_0 synthase K00705,K06044 GO:0000272,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009251,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016052,GO:0016853,GO:0016866,GO:0030978,GO:0030980,GO:0034637,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0047470,GO:0071704,GO:1901575,GO:1901576 2.4.1.25,5.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009452 551.0
HFD2_k127_1954560_1 Domain of unknown function (DUF3459) K01236 - 3.2.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004023 282.0
HFD2_k127_1970438_0 Sugar isomerase (SIS) K15916 - 5.3.1.8,5.3.1.9 0.000000000000000000000009775 106.0
HFD2_k127_1970438_1 PFAM zinc finger, SWIM domain protein - - - 0.000000000000000000007812 94.0
HFD2_k127_1973759_0 Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure - - - 0.00000000000000000000000000001147 121.0
HFD2_k127_1973759_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000009725 106.0
HFD2_k127_1973759_2 Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth - - - 0.0000000000000000000007096 100.0
HFD2_k127_1983907_0 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000008594 61.0
HFD2_k127_1994323_0 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000003296 222.0
HFD2_k127_1994323_1 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000002317 127.0
HFD2_k127_1994400_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000843 273.0
HFD2_k127_1994400_1 NADPH-dependent FMN reductase K19784 - - 0.000000000000000000000000000000000000000000000002277 179.0
HFD2_k127_1994400_2 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.000000000000000007137 96.0
HFD2_k127_2000642_0 Domain of unknown function (DUF1932) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002106 272.0
HFD2_k127_2000642_1 solute-binding protein K02027 - - 0.000000000000000000000000000000000000001227 155.0
HFD2_k127_2000642_2 response regulator - - - 0.0000000000001066 79.0
HFD2_k127_2001460_0 arylamine N-acetyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000929 278.0
HFD2_k127_2001460_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000002931 247.0
HFD2_k127_2001460_2 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000005657 206.0
HFD2_k127_2001460_3 YCII-related domain - - - 0.0000000000000000000000000000000000000000000607 164.0
HFD2_k127_2001460_4 - - - - 0.0002817 44.0
HFD2_k127_2012176_0 PFAM glucosamine galactosamine-6-phosphate isomerase K01057 - 3.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000003982 237.0
HFD2_k127_2012176_1 Glucose-6-phosphate dehydrogenase subunit - - - 0.000000000000000000000000000000001369 144.0
HFD2_k127_2012176_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000677 129.0
HFD2_k127_2039274_0 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008873 305.0
HFD2_k127_2039274_1 Bacterial transglutaminase-like N-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001924 252.0
HFD2_k127_2039274_2 Transglutaminase - - - 0.0000000000000000000000000000001725 128.0
HFD2_k127_2039717_0 Required for morphogenesis under gluconeogenic growth conditions - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 352.0
HFD2_k127_2039717_1 glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 295.0
HFD2_k127_2039717_2 helix-hairpin-helix K02237 - - 0.000000000000000000000000002126 120.0
HFD2_k127_2039717_3 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000003995 117.0
HFD2_k127_2039717_4 Preprotein translocase SecG subunit K03075 - - 0.000000000000006439 76.0
HFD2_k127_2039717_5 PFAM ComEC Rec2-related protein K02238 - - 0.000000000006312 75.0
HFD2_k127_2040041_0 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000000924 196.0
HFD2_k127_2040041_1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000001173 146.0
HFD2_k127_2040041_2 Belongs to the UPF0102 family K07460 - - 0.000000000000000000005194 96.0
HFD2_k127_2046745_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 341.0
HFD2_k127_2046745_1 NADPH-dependent FMN reductase - - - 0.0001651 44.0
HFD2_k127_2047844_0 PBP superfamily domain K03750,K07219 - 2.10.1.1 3.901e-247 779.0
HFD2_k127_2047844_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003308 281.0
HFD2_k127_2053405_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 398.0
HFD2_k127_2053405_1 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002706 274.0
HFD2_k127_2053405_2 4Fe-4S binding domain - - - 0.00000000000000002706 86.0
HFD2_k127_2054863_0 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005262 402.0
HFD2_k127_2054863_1 ATPase AAA-2 domain protein K03696 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 368.0
HFD2_k127_2054863_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001974 275.0
HFD2_k127_2054863_3 ATPase AAA-2 domain protein K03696 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009654 271.0
HFD2_k127_2054863_4 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000009574 124.0
HFD2_k127_2054863_5 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000003519 59.0
HFD2_k127_206380_0 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 312.0
HFD2_k127_206380_1 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 312.0
HFD2_k127_206380_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000002422 270.0
HFD2_k127_206380_3 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000000000000003056 228.0
HFD2_k127_206380_4 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000000000000000000003368 146.0
HFD2_k127_206380_5 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000009548 132.0
HFD2_k127_2078633_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000144 67.0
HFD2_k127_2078633_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000008147 61.0
HFD2_k127_2078633_2 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.0000002327 52.0
HFD2_k127_2078633_3 Carbamoyltransferase C-terminus K00612 - - 0.0005841 49.0
HFD2_k127_2079617_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain - - - 1.013e-223 719.0
HFD2_k127_2079617_1 alcohol dehydrogenase K00008,K08322 - 1.1.1.14,1.1.1.380 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004955 469.0
HFD2_k127_2079617_2 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K07112 - - 0.0000000000000000000000000000000000000000000000002195 183.0
HFD2_k127_2083942_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000762 476.0
HFD2_k127_2083942_1 PFAM Aminotransferase class I and II K05825 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005941 449.0
HFD2_k127_2083942_2 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 347.0
HFD2_k127_2083942_3 PFAM MaoC domain protein dehydratase K14449 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009436,GO:0009987,GO:0015977,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043427,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0046395,GO:0046487,GO:0071704,GO:0072329,GO:1901575 4.2.1.148 0.00000000000000000000000000000000000000000000000000000000000000000001518 239.0
HFD2_k127_2083942_4 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000002812 217.0
HFD2_k127_2083942_5 YjgF/chorismate_mutase-like, putative endoribonuclease - - - 0.00000000000000000000000000000000000000000000000003098 184.0
HFD2_k127_2083942_6 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000001211 166.0
HFD2_k127_2083942_7 Amidinotransferase - - - 0.000000000000000000000000000000000000000000039 171.0
HFD2_k127_2083942_8 iron dependent repressor K03709 - - 0.0000000000000000000000000000000000000000002645 166.0
HFD2_k127_2094771_0 PFAM short-chain dehydrogenase reductase SDR K00046 - 1.1.1.69 0.0000000000000000000000000000000000000000000000000007917 186.0
HFD2_k127_2094771_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000004167 76.0
HFD2_k127_2094771_2 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000002046 61.0
HFD2_k127_2107663_0 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 289.0
HFD2_k127_2107663_1 peptidyl-tyrosine sulfation - - - 0.00000000002061 69.0
HFD2_k127_2110043_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 309.0
HFD2_k127_2110043_1 Glycosyltransferase family 28 N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000004079 210.0
HFD2_k127_2115394_0 alcohol dehydrogenase K00008,K08322 - 1.1.1.14,1.1.1.380 0.0000000000000000000000000000007222 136.0
HFD2_k127_2115394_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000005069 133.0
HFD2_k127_2115394_2 ABC transporter substrate binding protein K01989 - - 0.000000000000000001995 94.0
HFD2_k127_2115394_3 - - - - 0.000000000000004984 87.0
HFD2_k127_2126959_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005787 347.0
HFD2_k127_2126959_1 Nitroreductase family - - - 0.000000000005658 66.0
HFD2_k127_2126959_2 Phosphopantetheine attachment site - - - 0.0000000003885 65.0
HFD2_k127_212882_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 437.0
HFD2_k127_2130575_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 2.548e-210 665.0
HFD2_k127_2130575_1 NAD(P)H quinone oxidoreductase, PIG3 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 297.0
HFD2_k127_2130575_2 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000006925 154.0
HFD2_k127_2130575_3 cytochrome P450 - - - 0.000000000000000000000000000000000001238 145.0
HFD2_k127_2130575_4 GDSL-like Lipase/Acylhydrolase - - - 0.0000000000000001604 89.0
HFD2_k127_2132822_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 6.778e-197 623.0
HFD2_k127_2132822_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 399.0
HFD2_k127_2132822_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004852 326.0
HFD2_k127_2132822_3 TIGRFAM phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000503 254.0
HFD2_k127_2132822_4 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000004884 229.0
HFD2_k127_2132822_5 Histidine biosynthesis bifunctional protein HisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000000000000007209 220.0
HFD2_k127_2132822_6 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000954 192.0
HFD2_k127_2132822_7 Kdo2-lipid A biosynthetic process K02517,K22311 - 2.3.1.241,2.3.1.265 0.0000000000000000000000000000000000000000000000000006729 194.0
HFD2_k127_2140108_0 Protein of unknown function (DUF3455) - - - 0.0000000000000000000000000000004129 132.0
HFD2_k127_2156202_0 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 454.0
HFD2_k127_2156202_1 Sodium:sulfate symporter transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000001051 228.0
HFD2_k127_2156202_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000001087 77.0
HFD2_k127_2156202_3 ABC transporter transmembrane region K02021 - - 0.0000000000006322 82.0
HFD2_k127_2161338_0 D-alanine [D-alanyl carrier protein] ligase activity K03367 GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016208,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0022857,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004772 454.0
HFD2_k127_2161338_1 negative regulation of protein lipidation K03739 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002819 406.0
HFD2_k127_2161338_2 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) K03740 - - 0.00000000000000000000000000000000000000000000000000000000000000000001636 250.0
HFD2_k127_2161338_3 regulatory protein GntR HTH - - - 0.0000000000000000000004402 106.0
HFD2_k127_2161338_4 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078,K14188 GO:0000270,GO:0003674,GO:0005215,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0022857,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.1.1.13 0.000000000000000007118 87.0
HFD2_k127_2161338_5 AMP-binding enzyme C-terminal domain - - - 0.00000152 50.0
HFD2_k127_2172150_0 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase K03429,K03715 - 2.4.1.315,2.4.1.46 0.00000000000000000000000000000000000000000003207 178.0
HFD2_k127_2172150_1 Endonuclease/Exonuclease/phosphatase family - - - 0.00000001294 60.0
HFD2_k127_2172150_2 Protein of unknown function (DUF2851) - - - 0.00000002506 61.0
HFD2_k127_2185143_0 PFAM Integrase catalytic region K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003992 276.0
HFD2_k127_2185143_1 Protein of unknown function (DUF2867) - - - 0.00000000000000000000000000000000000000000000000000000000000002567 222.0
HFD2_k127_2185143_2 Beta-lactamase - - - 0.000000008137 60.0
HFD2_k127_2185211_0 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00169,K19070 GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005347 577.0
HFD2_k127_2185211_1 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00170,K19071 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 513.0
HFD2_k127_2185211_2 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00171,K00172,K19072 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.000000000000000000000000000000000000000000006188 166.0
HFD2_k127_2185211_3 Putative cyclase - - - 0.0000000000000000000000000000000001001 136.0
HFD2_k127_2186695_0 PFAM CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000002408 208.0
HFD2_k127_2186695_1 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000007329 147.0
HFD2_k127_2186856_0 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004274 442.0
HFD2_k127_2186856_1 MmgE/PrpD family - - - 0.000000000000000000000000000000000000000000000226 185.0
HFD2_k127_2186856_2 carboxymuconolactone decarboxylase - - - 0.0000000000000000000000000000000000002524 149.0
HFD2_k127_2187299_0 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001724 281.0
HFD2_k127_2187299_1 metal-dependent hydrolase of the TIM-barrel fold K07046 - - 0.000000000000000000000000004857 112.0
HFD2_k127_2187299_2 - - - - 0.000000000000000006878 85.0
HFD2_k127_2190273_0 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000007337 236.0
HFD2_k127_2190273_1 Quinoprotein glucose dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000002346 231.0
HFD2_k127_2190273_2 pyrroloquinoline quinone binding - - - 0.00000000000000000000000000000000000000000000000123 194.0
HFD2_k127_2190273_3 Bacterial extracellular solute-binding protein - - - 0.000000000000000000000000000000000000001083 162.0
HFD2_k127_2190273_4 metal-dependent enzyme of the double-stranded beta helix superfamily - - - 0.0000000000008312 76.0
HFD2_k127_2196197_0 - - - - 0.00000000000000000000000000000000000000001009 173.0
HFD2_k127_2196197_1 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate K00108 - 1.1.99.1 0.000000003758 65.0
HFD2_k127_2211894_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008208 441.0
HFD2_k127_2211894_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 338.0
HFD2_k127_2211894_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K03074,K12257 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001319 287.0
HFD2_k127_2211894_3 PFAM Nucleotidyl transferase K00971,K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000000000000000003059 213.0
HFD2_k127_2221270_0 oligosaccharyl transferase activity K07151 - 2.4.99.18 0.000000000000000000000000000000000000000000000000000002765 211.0
HFD2_k127_2225017_0 PFAM ABC transporter transmembrane region K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005739 479.0
HFD2_k127_2225017_1 PFAM Transcriptional regulator - - - 0.0000000000000000001135 93.0
HFD2_k127_2231152_0 Transposase - - - 0.0000000000000000002621 89.0
HFD2_k127_2231152_1 X-Pro dipeptidyl-peptidase (S15 family) K06889 - - 0.0000004215 55.0
HFD2_k127_2236527_0 heavy metal translocating P-type ATPase K01533 - 3.6.3.4 6.672e-214 691.0
HFD2_k127_2236527_1 Belongs to the mandelate racemase muconate lactonizing enzyme family K01684 - 4.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 328.0
HFD2_k127_2236527_2 Belongs to the eIF-2B alpha beta delta subunits family K03680 - - 0.00000000000008061 76.0
HFD2_k127_2238241_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K00087 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 346.0
HFD2_k127_2238241_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000003711 164.0
HFD2_k127_2239806_0 ABC-type dipeptide oligopeptide nickel transport K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 304.0
HFD2_k127_2239806_1 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000169 206.0
HFD2_k127_2247000_0 synthetase K16029 - - 0.0000000000000002981 88.0
HFD2_k127_2258137_0 argininosuccinate lyase K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 480.0
HFD2_k127_2258137_1 metallopeptidase activity K06212,K06402 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016021,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0031224,GO:0031226,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 - 0.000000000000000000000000000000000000000000000000000000006535 211.0
HFD2_k127_2258137_2 COG1388 FOG LysM repeat K19223,K19224,K21471 - - 0.0000000000000000000000000000000005805 149.0
HFD2_k127_2258137_3 Belongs to the argininosuccinate synthase family. Type K01940 - 6.3.4.5 0.000000000000000001357 87.0
HFD2_k127_2266056_0 Putative modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009795 409.0
HFD2_k127_2269439_0 Phosphate ABC transporter, periplasmic phosphate-binding protein K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005817 441.0
HFD2_k127_2269439_1 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 353.0
HFD2_k127_2269439_2 Binding-protein-dependent transport system inner membrane component K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007201 349.0
HFD2_k127_2269439_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 354.0
HFD2_k127_2269439_4 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000006758 220.0
HFD2_k127_2283334_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 439.0
HFD2_k127_2283334_1 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000004583 127.0
HFD2_k127_2285343_0 Thiamine pyrophosphate enzyme, central domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 355.0
HFD2_k127_2285343_1 BAAT / Acyl-CoA thioester hydrolase C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 313.0
HFD2_k127_2285343_2 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000008607 181.0
HFD2_k127_2285343_3 - - - - 0.000000000000000337 83.0
HFD2_k127_2285343_4 VWA domain containing CoxE-like protein K07161 - - 0.0000000000004617 76.0
HFD2_k127_229927_0 Acyl-transferase - - - 0.000000000000000000000000000000000000000000000000000000000003532 224.0
HFD2_k127_229927_1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000007198 97.0
HFD2_k127_2307945_0 PFAM transposase, mutator - - - 0.000000000000000000000000000000000000000000000008132 175.0
HFD2_k127_2307945_1 PFAM transposase, mutator - - - 0.000000000000000000000006148 103.0
HFD2_k127_2307945_2 PFAM transposase, mutator - - - 0.0000000000000000001093 90.0
HFD2_k127_2307945_3 Transposase - - - 0.0000001104 57.0
HFD2_k127_2307945_4 COG0542 ATPases with chaperone activity, ATP-binding subunit - - - 0.0009538 45.0
HFD2_k127_2317508_0 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 2.368e-294 925.0
HFD2_k127_2317508_1 Protein of unknown function (DUF3500) - - - 0.0000000000000000000000000000000000000000000000001692 182.0
HFD2_k127_2317508_2 mercury ion transmembrane transporter activity K07213 - - 0.000004406 57.0
HFD2_k127_2320323_0 TIGRFAM MazG family protein K02428,K02499,K04765 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66,3.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000578 237.0
HFD2_k127_2320323_1 Immune inhibitor A peptidase M6 - - - 0.0002209 47.0
HFD2_k127_2321114_0 PFAM peptidase M22 glycoprotease K14742 - - 0.0000000000000000000000000000000000000000000004442 175.0
HFD2_k127_2321114_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000157 127.0
HFD2_k127_2321114_2 ATPase or kinase K06925 GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000000000000001025 109.0
HFD2_k127_2321114_3 FR47-like protein K03789 - 2.3.1.128 0.000002884 50.0
HFD2_k127_2337902_0 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 455.0
HFD2_k127_2337902_1 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 420.0
HFD2_k127_2337902_2 Belongs to the glycosyl hydrolase 26 family - - - 0.0000000000000000000000000000000000000000000000000000007159 213.0
HFD2_k127_2337902_3 PFAM GGDEF domain containing protein K21020 - 2.7.7.65 0.0000000000628 74.0
HFD2_k127_2343187_0 PFAM FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006157 425.0
HFD2_k127_2343187_1 Beta-lactamase superfamily domain - - - 0.0000000000000000000000004662 117.0
HFD2_k127_2343187_2 Transition state regulatory protein AbrB K07120 - - 0.0000000000000000000242 98.0
HFD2_k127_2343187_3 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000000000000000819 94.0
HFD2_k127_2343187_4 Pfam:AmoA K07120 - - 0.000672 51.0
HFD2_k127_2347733_0 Zn peptidase K21686 - - 0.000000000000000000000000000000000000000000001783 176.0
HFD2_k127_2347733_1 Helix-turn-helix domain - - - 0.0000000000000001359 84.0
HFD2_k127_2356681_0 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 361.0
HFD2_k127_2356681_1 Glycosyl transferase family 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000157 246.0
HFD2_k127_2356681_2 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.0000000000000000000000000000000000000000003631 169.0
HFD2_k127_2358844_0 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666,K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003178 325.0
HFD2_k127_2358844_1 Putative restriction endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000457 228.0
HFD2_k127_2358844_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000002046 145.0
HFD2_k127_2359778_0 cellulose binding - - - 4.569e-206 651.0
HFD2_k127_2359778_1 cysteine protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003344 395.0
HFD2_k127_2359778_10 Multicopper oxidase - - - 0.00073 44.0
HFD2_k127_2359778_2 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 398.0
HFD2_k127_2359778_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004632 267.0
HFD2_k127_2359778_4 Belongs to the binding-protein-dependent transport system permease family K01998,K11961 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001228 258.0
HFD2_k127_2359778_5 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000183 235.0
HFD2_k127_2359778_6 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000005206 193.0
HFD2_k127_2359778_7 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.0000000000000000000000000000000000000001083 156.0
HFD2_k127_2359778_8 Thioesterase superfamily K18700 - 3.1.2.29 0.0000000000000000000000000000000000004809 146.0
HFD2_k127_2359778_9 - - - - 0.0000000000002137 75.0
HFD2_k127_2363049_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 2.312e-252 791.0
HFD2_k127_2363049_1 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 489.0
HFD2_k127_2363049_2 Belongs to the LDH MDH superfamily. LDH family K00016 - 1.1.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000744 284.0
HFD2_k127_2363049_3 Divergent PAP2 family K09775 - - 0.0000000000000000000000000000000001109 137.0
HFD2_k127_2363049_4 Sortase family - - - 0.0000000000000000000000009875 111.0
HFD2_k127_2363049_5 WYL domain K13572 - - 0.000000000000000002619 93.0
HFD2_k127_2363049_6 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000129 83.0
HFD2_k127_2363049_7 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000001528 64.0
HFD2_k127_2363049_8 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 3.1.11.6 0.0000000351 58.0
HFD2_k127_2376462_0 TIGRFAM amino acid adenylation domain - - - 0.0 1529.0
HFD2_k127_2376462_1 COGs COG1020 Non-ribosomal peptide synthetase modules and related protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 602.0
HFD2_k127_2376462_2 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000008533 202.0
HFD2_k127_2380713_0 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 334.0
HFD2_k127_2380713_1 PFAM conserved K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001672 265.0
HFD2_k127_2380713_2 PFAM O-antigen polymerase - - - 0.000000000000000000000000000000000000000000000000000000000155 222.0
HFD2_k127_2380713_3 O-Antigen ligase - - - 0.0000000000000000000000000000000000000002179 157.0
HFD2_k127_2399065_0 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000805 431.0
HFD2_k127_2399065_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169,K03737 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007585 408.0
HFD2_k127_239955_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004172 570.0
HFD2_k127_239955_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 357.0
HFD2_k127_239955_2 - - - - 0.000000000000000001051 93.0
HFD2_k127_2404166_0 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 325.0
HFD2_k127_2404166_1 PFAM luciferase-like - - - 0.00000000000000000000000000000000000000000000001128 189.0
HFD2_k127_2404166_2 FAD dependent oxidoreductase - - - 0.0000000000001133 85.0
HFD2_k127_2404166_3 SnoaL-like polyketide cyclase K07255 - - 0.00000001553 57.0
HFD2_k127_2406791_0 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.00000000000000000000000000000000000000000000214 170.0
HFD2_k127_2406966_0 Phosphotriesterase K07048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009614 304.0
HFD2_k127_2408378_0 Penicillin-binding Protein dimerisation domain K03587,K08384 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 396.0
HFD2_k127_2408378_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 347.0
HFD2_k127_2408378_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003347 342.0
HFD2_k127_2408378_3 Mur ligase family, catalytic domain K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008067 331.0
HFD2_k127_2408378_4 TIGRFAM cell division protein FtsW K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 313.0
HFD2_k127_2408378_5 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 308.0
HFD2_k127_2408378_6 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000001166 176.0
HFD2_k127_2408378_7 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - - - 0.0000000000000000000000000000000001553 141.0
HFD2_k127_2408378_8 MraZ protein, putative antitoxin-like K03925 - - 0.000000000000000000000000000000005637 132.0
HFD2_k127_2408378_9 Zn-ribbon protein possibly nucleic acid-binding K07164 - - 0.0000000000001815 80.0
HFD2_k127_24146_0 PFAM FAD dependent oxidoreductase K00301 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 514.0
HFD2_k127_24146_1 response regulator K07668,K07775 - - 0.0000000000000000000000000000000000000000000000000000000000002266 226.0
HFD2_k127_24146_2 protein histidine kinase activity K01768,K02484,K07636,K10681,K10819,K18350,K20487 - 2.7.13.3,4.6.1.1 0.000000000000000000000000000000000000000000000000000004868 209.0
HFD2_k127_24146_3 FAD dependent oxidoreductase K00301,K02846 - 1.5.3.1 0.000000000000000000000000000000000000001457 163.0
HFD2_k127_24146_4 ferredoxin K05524 - - 0.00000000000000000000000000000385 121.0
HFD2_k127_2425463_0 membrane - - - 0.00000000000000000000000000000000000000000000000000001515 194.0
HFD2_k127_2425463_1 trisaccharide binding K03556 - - 0.0000000000000000000000000000000000000000000000149 183.0
HFD2_k127_2427203_0 Mo-co oxidoreductase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001287 239.0
HFD2_k127_2427203_1 NIPSNAP - - - 0.00000000000000000000000000000000000000000000000000000007509 203.0
HFD2_k127_2430134_0 Conserved region in glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 1952.0
HFD2_k127_2436114_0 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.00000000000000000000538 94.0
HFD2_k127_2436114_1 lipolytic protein G-D-S-L family - - - 0.000000000000000002598 98.0
HFD2_k127_2442092_0 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000006629 217.0
HFD2_k127_2442092_1 Beta-lactamase superfamily domain - - - 0.00000000000000000000000003212 120.0
HFD2_k127_2442092_2 Beta-lactamase superfamily domain - - - 0.000000000000000000000009572 112.0
HFD2_k127_2442092_3 C-terminal four TMM region of protein-O-mannosyltransferase K00728 - 2.4.1.109 0.00000000006584 70.0
HFD2_k127_2453783_0 Domain of unknown function DUF87 K06915 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 582.0
HFD2_k127_2453783_1 Rad50 zinc hook motif K03546 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005492 414.0
HFD2_k127_2453783_2 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03546,K03547 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 340.0
HFD2_k127_2453783_3 HAS barrel domain - - - 0.0000000000000000000000000000000000000000000000001921 182.0
HFD2_k127_2457396_0 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004491 280.0
HFD2_k127_2457396_1 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000007619 214.0
HFD2_k127_2457396_2 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000002866 213.0
HFD2_k127_2457396_3 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000001016 100.0
HFD2_k127_2461617_0 Domain of unknown function (DUF4010) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 369.0
HFD2_k127_2461617_1 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000002371 115.0
HFD2_k127_246348_0 Leucine carboxyl methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009579 282.0
HFD2_k127_246348_1 - - - - 0.000000000000000000000000634 108.0
HFD2_k127_2464168_0 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000069 541.0
HFD2_k127_2464168_1 ABC-type dipeptide transport system periplasmic component K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005101 464.0
HFD2_k127_2464168_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000001648 89.0
HFD2_k127_2464168_3 ABC-2 family transporter protein K01992 - - 0.0000000004851 63.0
HFD2_k127_2473833_0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K01576 - 4.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000005442 269.0
HFD2_k127_2473833_1 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000198 77.0
HFD2_k127_2473833_2 - - - - 0.00000000006352 68.0
HFD2_k127_2473833_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000001457 57.0
HFD2_k127_2473833_4 FecR protein - - - 0.0006116 51.0
HFD2_k127_2477534_0 Two component transcriptional regulator, winged helix family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001084 259.0
HFD2_k127_2477534_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000004483 208.0
HFD2_k127_2477534_2 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01697,K01738,K12339 - 2.5.1.47,4.2.1.22 0.0000000000000000000000000000000008632 132.0
HFD2_k127_2477534_3 proteolysis K21140 - 3.13.1.6 0.000000000000000000000000021 113.0
HFD2_k127_2485014_0 4,5-dihydroxyphthalate decarboxylase K04102 - 4.1.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003988 308.0
HFD2_k127_2485014_1 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004191 289.0
HFD2_k127_2485014_2 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000004551 214.0
HFD2_k127_2485014_3 NMT1/THI5 like K02051 - - 0.000000000000000000000000000000000000000000000005411 188.0
HFD2_k127_2497496_0 Heat shock 70 kDa protein K04043 - - 1.125e-290 902.0
HFD2_k127_2497496_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007589 615.0
HFD2_k127_2497496_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 451.0
HFD2_k127_2498297_0 Histidine kinase K12257 - - 0.0 1422.0
HFD2_k127_2498297_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002868 236.0
HFD2_k127_2501035_0 ATPase associated with various cellular activities, AAA_3 K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003864 394.0
HFD2_k127_2501035_1 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 377.0
HFD2_k127_2501035_2 Stage II sporulation protein M - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003565 249.0
HFD2_k127_2501035_3 Domain of unknown function (DUF4350) - - - 0.00000000000000000000000000000000009143 147.0
HFD2_k127_2501035_4 PFAM RDD domain containing protein - - - 0.0000000000000000004237 91.0
HFD2_k127_2501035_5 Domain of unknown function (DUF4129) - - - 0.000000000002747 70.0
HFD2_k127_2504633_0 COG1053 Succinate dehydrogenase fumarate reductase flavoprotein subunit K13796 - - 4.908e-195 620.0
HFD2_k127_2504633_1 Belongs to the thiolase family K00626,K02615 - 2.3.1.174,2.3.1.223,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009006 546.0
HFD2_k127_2504633_2 Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma- L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007212 441.0
HFD2_k127_2504633_3 TIGRFAM CitB domain protein K13795 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 352.0
HFD2_k127_2504633_4 Transketolase, pyrimidine binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005683 281.0
HFD2_k127_2504633_5 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001027 274.0
HFD2_k127_2504633_6 PFAM UspA domain protein - - - 0.00000000000000000000000000000000000006508 153.0
HFD2_k127_2504633_7 - - - - 0.00000000001192 70.0
HFD2_k127_2506372_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07239 - - 1.475e-308 960.0
HFD2_k127_2511155_0 Epoxide hydrolase N terminus K01253 - 3.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005328 475.0
HFD2_k127_2511155_1 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.00000000000000000000000000000000000000000000000000000000000000006111 237.0
HFD2_k127_2511155_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000007509 192.0
HFD2_k127_2511155_3 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000203 203.0
HFD2_k127_2511155_4 PFAM Glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.00000000000000000000002309 104.0
HFD2_k127_2511155_5 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01856,K19802 - 5.1.1.20,5.5.1.1 0.000002216 54.0
HFD2_k127_2517037_0 Carbamoyltransferase C-terminus K00612 - - 3.745e-230 726.0
HFD2_k127_2517037_1 Belongs to the 3-hydroxyisobutyrate dehydrogenase family K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000001633 266.0
HFD2_k127_2517037_2 Predicted membrane protein (DUF2085) - - - 0.000000000000000000000000000000000000000001076 165.0
HFD2_k127_2517037_3 PFAM Integral membrane protein 1906 - - - 0.00000000000000000000000001131 118.0
HFD2_k127_2517037_4 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000003732 117.0
HFD2_k127_2517037_5 Protein of unknown function (DUF503) K09764 - - 0.00000000000000000005268 93.0
HFD2_k127_2517037_6 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000005706 64.0
HFD2_k127_2517037_7 - - - - 0.000000004584 62.0
HFD2_k127_2517037_8 Rhodanese-like protein - - - 0.000001053 54.0
HFD2_k127_2517037_9 - - - - 0.000003938 55.0
HFD2_k127_2529395_0 Pyruvate ferredoxin oxidoreductase and related K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009005 527.0
HFD2_k127_2529395_1 FAD linked oxidases, C-terminal domain K00104,K18930 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 493.0
HFD2_k127_2529395_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 379.0
HFD2_k127_2529395_3 PFAM thiamine pyrophosphate protein domain protein TPP-binding K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009496 295.0
HFD2_k127_2529395_4 EVE domain - - - 0.000000000000000000000000000000000001391 145.0
HFD2_k127_2529395_5 phosphatase - - - 0.00025 45.0
HFD2_k127_2543459_0 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003362 349.0
HFD2_k127_2543459_1 Methyl-accepting chemotaxis protein (MCP) signaling domain K02660,K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001988 297.0
HFD2_k127_2543459_2 GGDEF domain K02657 - - 0.000000000000000000000000000000000001358 142.0
HFD2_k127_2543459_3 response regulator, receiver K02658 - - 0.000000000000000000000000000000001431 135.0
HFD2_k127_2543459_4 chemotaxis K03408 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006935,GO:0008150,GO:0009605,GO:0019904,GO:0040011,GO:0042221,GO:0042330,GO:0044424,GO:0044444,GO:0044464,GO:0050896 - 0.00000000000000000006373 99.0
HFD2_k127_2543459_5 competence protein COMEC K02238 - - 0.0000007077 61.0
HFD2_k127_2543459_6 NADPH-dependent FMN reductase K19784 - - 0.00002059 54.0
HFD2_k127_2544918_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006834 485.0
HFD2_k127_2544918_1 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000001524 152.0
HFD2_k127_2544918_2 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000001458 104.0
HFD2_k127_2544918_3 Belongs to the bacterial ribosomal protein bL36 family K02919 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000001965 68.0
HFD2_k127_2553212_0 F5/8 type C domain - - - 0.0000000000000000004199 100.0
HFD2_k127_2558589_0 SMP-30/Gluconolaconase/LRE-like region K01053,K14274 - 3.1.1.17 6.487e-197 620.0
HFD2_k127_2558589_1 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000009179 55.0
HFD2_k127_256478_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 418.0
HFD2_k127_256478_1 PFAM amino acid-binding ACT domain protein K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000001409 191.0
HFD2_k127_256478_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000002405 91.0
HFD2_k127_2567337_0 ABC-type uncharacterized transport system K01992 - - 0.000000000000000001465 89.0
HFD2_k127_2567337_1 Luciferase-like monooxygenase - - - 0.0000000000006673 76.0
HFD2_k127_2567337_2 Domain of unknown function (DUF4340) - - - 0.00000000003931 74.0
HFD2_k127_2591833_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 343.0
HFD2_k127_2591833_1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000000000000000000000000000000000003595 226.0
HFD2_k127_2591833_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000005974 185.0
HFD2_k127_2591833_3 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000001212 183.0
HFD2_k127_2591833_4 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000003915 164.0
HFD2_k127_2591833_5 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000000000000000000003615 143.0
HFD2_k127_2591833_6 Flagellar filament outer layer protein Flaa - - - 0.00000000000000000001105 108.0
HFD2_k127_2591833_7 PFAM pentapeptide repeat protein - - - 0.0000000000000000005382 98.0
HFD2_k127_2591833_8 DsrE/DsrF-like family - - - 0.00000000002486 66.0
HFD2_k127_2591833_9 Short repeat of unknown function (DUF308) - - - 0.000005703 54.0
HFD2_k127_2592623_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003808 393.0
HFD2_k127_2592623_1 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006666 358.0
HFD2_k127_2592623_2 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000002462 265.0
HFD2_k127_2612725_0 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 612.0
HFD2_k127_2612725_1 Pfam:Pyridox_oxidase K07006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002243 276.0
HFD2_k127_2612725_2 cheY-homologous receiver domain K11443 - - 0.0000000000000000000000000000000000000000000000001351 180.0
HFD2_k127_2612725_3 Glycosyl transferases group 1 - - - 0.00000000000000000000000005768 124.0
HFD2_k127_2612725_4 Protein of unknown function (DUF983) - - - 0.0000000000000000000000005046 109.0
HFD2_k127_262931_0 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000001621 209.0
HFD2_k127_262931_1 Crp-like helix-turn-helix domain K10914 - - 0.000000000000000000000000000003437 127.0
HFD2_k127_262931_2 SNARE associated Golgi protein - - - 0.00000000000000001122 92.0
HFD2_k127_2659113_0 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.0000000000000000000000000000000000000000000000000000000000000000001498 238.0
HFD2_k127_2659113_1 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000005629 162.0
HFD2_k127_2659113_2 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000001225 128.0
HFD2_k127_2659113_3 - - - - 0.0000000000000000000000000007444 119.0
HFD2_k127_2659113_4 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K20023 - 4.2.1.156,4.2.1.42 0.0002204 49.0
HFD2_k127_2663757_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 390.0
HFD2_k127_2663757_1 photosynthesis - - - 0.000000000000000000000000000000000000008074 151.0
HFD2_k127_2663757_2 nUDIX hydrolase - GO:0003674,GO:0003824,GO:0016787,GO:0016817,GO:0016818 - 0.0000000000000000000000000000000000000191 151.0
HFD2_k127_2676414_0 PFAM Glycosyl transferase, group 1 - GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.00000000000000000000000000000000000000000000000000000000000000000000000001733 267.0
HFD2_k127_2676414_1 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000004516 241.0
HFD2_k127_2676414_2 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000001069 177.0
HFD2_k127_2676414_3 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00008977 49.0
HFD2_k127_267861_0 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000003611 149.0
HFD2_k127_267861_1 Protein of unknown function (DUF3151) - - - 0.000000000000000000000000000000001712 137.0
HFD2_k127_267861_2 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K06989 - 1.4.1.21 0.00000000000000000009825 98.0
HFD2_k127_2690030_0 IS66 C-terminal element - - - 0.000000000000004425 74.0
HFD2_k127_2701760_0 AraC-like ligand binding domain - - - 0.0000000000000000000000000000000000000000000000000003982 186.0
HFD2_k127_2701760_1 PFAM FAD dependent oxidoreductase K03153 - 1.4.3.19 0.00000000000000000000000000000000000000000000009977 184.0
HFD2_k127_2701760_2 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000003948 159.0
HFD2_k127_2701760_3 HpcH/HpaI aldolase/citrate lyase family - - - 0.00000000000000000000000000000000000002181 153.0
HFD2_k127_2701760_4 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.000000000000000001982 94.0
HFD2_k127_2701760_5 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.00000000000000000768 89.0
HFD2_k127_2701760_6 PFAM blue (type 1) copper domain protein - - - 0.00000000000000002081 87.0
HFD2_k127_2701760_7 COG3119 Arylsulfatase A and related enzymes - - - 0.0000006805 52.0
HFD2_k127_2715433_0 PFAM WD40 domain protein beta Propeller K03641 - - 0.00000000000000000000000000000000000000000001734 174.0
HFD2_k127_2725742_0 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002525 254.0
HFD2_k127_2725742_1 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000000000000004322 219.0
HFD2_k127_2725742_2 Molybdenum cofactor synthesis domain - - - 0.0000000000000000000000000000000000000000000000000000186 195.0
HFD2_k127_2731712_0 NlpC/P60 family - - - 0.0000000000000000000000000000000000000001238 163.0
HFD2_k127_2731712_1 Glutamine synthetase N-terminal domain K01915 - 6.3.1.2 0.00000000000000000000000000000000000000335 150.0
HFD2_k127_2747716_0 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 374.0
HFD2_k127_2747716_1 COG1228 Imidazolonepropionase and related - - - 0.000000000000000000000000000000000007443 154.0
HFD2_k127_2754048_0 Aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005146 350.0
HFD2_k127_2754048_1 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 331.0
HFD2_k127_2754048_2 - - - - 0.0000000000000000000000009107 111.0
HFD2_k127_2754048_3 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.00000000000000000000000165 118.0
HFD2_k127_2754048_4 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.00000000000000000003178 93.0
HFD2_k127_2754048_5 Major facilitator Superfamily - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.0000000000000001258 84.0
HFD2_k127_2754048_6 ubiE/COQ5 methyltransferase family - - - 0.00000000000003544 81.0
HFD2_k127_2759184_0 Esterase-like activity of phytase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006529 262.0
HFD2_k127_2759184_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00018 - 1.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000005854 233.0
HFD2_k127_2759184_2 PFAM pyridoxamine 5'-phosphate oxidase-related - - - 0.0000000005085 66.0
HFD2_k127_2760188_0 Magnesium chelatase, subunit ChlI K07391 - - 2.284e-207 656.0
HFD2_k127_2760188_1 Ankyrin repeats (many copies) - - - 0.00000000000000000000000000000000003023 136.0
HFD2_k127_2760188_2 Flavin containing amine oxidoreductase - - - 0.000000000000000443 83.0
HFD2_k127_2762649_0 COGs COG3220 conserved K09930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000984 405.0
HFD2_k127_2762649_1 belongs to the UPF0276 family - - - 0.000001604 55.0
HFD2_k127_2762649_2 phenylacetate-CoA ligase activity - - - 0.00000308 57.0
HFD2_k127_2764489_0 Belongs to the mandelate racemase muconate lactonizing enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007949 408.0
HFD2_k127_2764489_1 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000000000005533 158.0
HFD2_k127_2764489_2 PFAM phospholipase Carboxylesterase K06999 - - 0.0000000000000000000000000000000001135 142.0
HFD2_k127_2764489_3 Belongs to the glycosyl hydrolase 3 family K01207 - 3.2.1.52 0.000000000000000001188 89.0
HFD2_k127_2764489_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000003025 72.0
HFD2_k127_2772031_0 bacterial-type flagellum-dependent cell motility - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 404.0
HFD2_k127_2772031_1 Belongs to the peptidase S8 family K13274,K14645 - - 0.00000000000000000000000000000000000000000000000000000000000001587 231.0
HFD2_k127_2772031_2 Spore Coat K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000131 198.0
HFD2_k127_2772031_3 Protein of unknown function (DUF3500) - - - 0.000000000000000000000000000000000001481 142.0
HFD2_k127_2772031_4 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000003992 127.0
HFD2_k127_2772031_5 Belongs to the peptidase S8 family - - - 0.000000004205 70.0
HFD2_k127_2772031_6 Peptidase_C39 like family - - - 0.00007439 55.0
HFD2_k127_2772031_7 domain protein - - - 0.0002258 54.0
HFD2_k127_2782305_0 CT1975-like protein K19124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 340.0
HFD2_k127_2782305_1 CRISPR-associated protein (Cas_Cas5) K19125 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005747 271.0
HFD2_k127_2782305_2 CRISPR_assoc K19126 - - 0.00000000000000000000000000000000000000000000000000000000000000007951 237.0
HFD2_k127_2793249_0 Natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 517.0
HFD2_k127_2793249_1 MgtE intracellular N domain - - - 0.00000000000000000000000000000000000000000000000000000000000001339 220.0
HFD2_k127_2793249_2 Pfam Chromate transporter K07240 - - 0.0000000000000000000000000000000000000000001641 165.0
HFD2_k127_2793249_3 chromate transporter K07240 - - 0.000000000000000000000000000000000001388 149.0
HFD2_k127_2793249_4 ABC transporter substrate binding protein K01989 - - 0.00000000000000002456 81.0
HFD2_k127_2807170_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 389.0
HFD2_k127_2807170_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 373.0
HFD2_k127_2816785_0 N-methylhydantoinase A acetone carboxylase, beta subunit K01469,K01473 - 3.5.2.14,3.5.2.9 1.169e-235 746.0
HFD2_k127_2819314_0 Releases the N-terminal proline from various substrates K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006452 308.0
HFD2_k127_2819314_1 cytochrome - - - 0.000000000000000000000000000000000123 140.0
HFD2_k127_2819314_2 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000004259 136.0
HFD2_k127_2824906_0 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 467.0
HFD2_k127_2824906_1 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004247 418.0
HFD2_k127_2824906_2 PFAM extracellular solute-binding protein, family 5 K02035,K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 324.0
HFD2_k127_2824906_3 Belongs to the UPF0284 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001516 273.0
HFD2_k127_2824906_4 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009281 263.0
HFD2_k127_2824906_5 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.0000000000000000000000000000000000000000000000000000000005771 211.0
HFD2_k127_2824906_6 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008463,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.000000000000000000000000000000000000000188 156.0
HFD2_k127_2824906_7 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.000000000000000000000000000000001182 140.0
HFD2_k127_2828286_0 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 3.267e-238 767.0
HFD2_k127_2828286_1 Belongs to the dCTP deaminase family K01494 GO:0003674,GO:0003824,GO:0004170,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0019239,GO:0033973,GO:0047429 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000002635 239.0
HFD2_k127_2828286_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000003647 206.0
HFD2_k127_2828286_3 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000001266 170.0
HFD2_k127_2828286_4 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000000000000000004041 148.0
HFD2_k127_2828286_5 FR47-like protein - - - 0.00000000000000000007605 98.0
HFD2_k127_2828286_6 Belongs to the class-II aminoacyl-tRNA synthetase family K01868 - 6.1.1.3 0.000000000000000004067 91.0
HFD2_k127_2828286_7 CAAX amino terminal protease family K07052 - - 0.0000000000006482 80.0
HFD2_k127_2828286_8 Bacterial membrane protein YfhO - - - 0.000000000008914 78.0
HFD2_k127_2838269_0 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006912 306.0
HFD2_k127_2838269_1 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000009257 120.0
HFD2_k127_2840374_0 GXGXG motif K00265 - 1.4.1.13,1.4.1.14 0.0 1304.0
HFD2_k127_2840374_1 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000002585 267.0
HFD2_k127_2853938_0 Oxidoreductase - - - 0.0000000000000000000000000000000000005603 151.0
HFD2_k127_2853938_1 Major Facilitator Superfamily - - - 0.0000000000000000000000002392 120.0
HFD2_k127_2853938_2 ATP-dependent DNA helicase activity - - - 0.0000000000000000000005839 106.0
HFD2_k127_2855649_0 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone K15510 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016491,GO:0016614,GO:0019725,GO:0030312,GO:0031406,GO:0036094,GO:0042592,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043177,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0046983,GO:0048037,GO:0050662,GO:0050789,GO:0050794,GO:0055114,GO:0065007,GO:0065008,GO:0070967,GO:0071944,GO:0097159,GO:0097367,GO:1901363 1.1.98.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004805 490.0
HFD2_k127_2855649_1 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004257 308.0
HFD2_k127_2855649_2 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000001254 239.0
HFD2_k127_2855649_3 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000000000000000000232 122.0
HFD2_k127_2855649_4 phosphorelay signal transduction system - - - 0.0000000000000000000009399 108.0
HFD2_k127_2859736_0 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 334.0
HFD2_k127_2859736_1 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003853 267.0
HFD2_k127_2866853_0 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 570.0
HFD2_k127_2869793_0 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002451 287.0
HFD2_k127_2869793_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000004626 159.0
HFD2_k127_2869793_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03117 - - 0.00000000006531 63.0
HFD2_k127_2900052_0 Protein of unknown function, DUF255 K06888 - - 1.345e-197 627.0
HFD2_k127_2900052_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000002156 126.0
HFD2_k127_2900998_0 ATPase P-type (Transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1109.0
HFD2_k127_2900998_1 Formate/nitrite transporter K06212 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005381 274.0
HFD2_k127_2900998_2 PFAM UspA domain protein - - - 0.0000000000000000000000000000000000000000000000000000008779 206.0
HFD2_k127_2900998_3 translation release factor activity K03265 GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0016020,GO:0030312,GO:0036293,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944 - 0.0000000000000000000000000000000008903 143.0
HFD2_k127_2907282_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 386.0
HFD2_k127_2907282_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000008571 239.0
HFD2_k127_2907282_2 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000072 190.0
HFD2_k127_2912486_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 311.0
HFD2_k127_2912486_1 COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily K18983 - 5.5.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005429 314.0
HFD2_k127_2912486_2 Esterase-like activity of phytase - - - 0.0000000000000000000000000000000000000000000000000000000000000006523 242.0
HFD2_k127_2912486_3 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000003402 154.0
HFD2_k127_2912486_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit - - - 0.000000000000000000000001652 109.0
HFD2_k127_2912486_5 COG3666 Transposase and inactivated derivatives - - - 0.00000000000000002085 83.0
HFD2_k127_2919612_0 Plasmid pRiA4b ORF-3-like protein - - - 0.000000000000000000000000000000000000000000000000000000002274 204.0
HFD2_k127_2919612_1 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000000000000000005351 199.0
HFD2_k127_2919612_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000004906 102.0
HFD2_k127_2987923_0 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000004489 222.0
HFD2_k127_2987923_1 - - - - 0.000000000000000000000000000000000000000000001548 171.0
HFD2_k127_2987923_2 Involved in the tonB-independent uptake of proteins K03641 - - 0.0000000000000000000000000000000002873 147.0
HFD2_k127_3006227_0 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006627 373.0
HFD2_k127_3006227_1 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000671 174.0
HFD2_k127_3006227_2 Chromate transporter K07240 - - 0.000000000000000000000000000000001189 136.0
HFD2_k127_3006227_3 PFAM IS1 transposase K07480 - - 0.0000000000000000000000005744 106.0
HFD2_k127_3006463_0 Integral membrane protein TerC family K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 372.0
HFD2_k127_3006463_1 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007355 282.0
HFD2_k127_3014351_0 Anticodon-binding domain of tRNA K01870 - 6.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005377 584.0
HFD2_k127_3019477_0 PFAM polysaccharide biosynthesis protein - - - 0.000000007211 60.0
HFD2_k127_3019477_1 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000002114 61.0
HFD2_k127_3019477_2 - K07098 - - 0.00001808 52.0
HFD2_k127_302359_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.000000000000000000000000000000000000001824 155.0
HFD2_k127_302359_1 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.0000000000000000000000000000002767 137.0
HFD2_k127_302359_2 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.00000003465 63.0
HFD2_k127_302695_0 CHAT domain - - - 0.0000000000000001424 90.0
HFD2_k127_302695_1 - - - - 0.000004239 55.0
HFD2_k127_3030850_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 6.018e-309 965.0
HFD2_k127_3030850_1 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001498 271.0
HFD2_k127_3030850_2 SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000006096 231.0
HFD2_k127_3030850_3 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000003975 180.0
HFD2_k127_3030850_4 Polysaccharide deacetylase K22278 - 3.5.1.104 0.000000000000000000000000000000000001139 154.0
HFD2_k127_3030850_5 - - - - 0.0000001051 57.0
HFD2_k127_3035501_0 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005587 258.0
HFD2_k127_3035501_1 Histidine kinase K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000008069 216.0
HFD2_k127_3035501_2 Response regulator receiver - - - 0.0001227 51.0
HFD2_k127_3062841_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008135 480.0
HFD2_k127_3062841_1 ABC-type multidrug transport system, permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 297.0
HFD2_k127_3062841_2 ABC-2 family transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000001067 227.0
HFD2_k127_3062841_3 PFAM DoxX family protein K16937 - 1.8.5.2 0.0000000000000000000000000000000000000000000000001446 181.0
HFD2_k127_3062841_4 Barrel-sandwich domain of CusB or HlyD membrane-fusion K01993 - - 0.00000000000000000000000000000000003868 143.0
HFD2_k127_3064991_0 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 9.374e-245 767.0
HFD2_k127_3064991_1 TIGRFAM methylmalonyl-CoA mutase, large subunit K01848 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005117 499.0
HFD2_k127_3064991_2 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002774 433.0
HFD2_k127_3064991_3 TIGRFAM Methylmalonyl-CoA mutase, C-terminal K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000008817 191.0
HFD2_k127_3064991_4 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.0000000000000000000000000000003324 127.0
HFD2_k127_3077540_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005064 478.0
HFD2_k127_3077540_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000004067 273.0
HFD2_k127_3077540_2 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000001236 144.0
HFD2_k127_3077540_3 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0000000003963 63.0
HFD2_k127_3081314_0 Putative glycosyl hydrolase domain - - - 0.000000000000000000000000000000000000000000000004868 178.0
HFD2_k127_3081314_1 AMP-binding enzyme K01912 - 6.2.1.30 0.000423 53.0
HFD2_k127_3098088_0 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 2.422e-226 721.0
HFD2_k127_3098088_1 PFAM molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005155 404.0
HFD2_k127_3098088_2 Biotin carboxyl carrier protein K01960 - 6.4.1.1 0.000000000000004092 81.0
HFD2_k127_3098437_0 ATPase P-type (Transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 9.717e-216 694.0
HFD2_k127_3098437_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004167 337.0
HFD2_k127_3098437_2 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07667 - - 0.0000005975 53.0
HFD2_k127_3098437_3 Transposase and inactivated derivatives K07497 - - 0.0006911 42.0
HFD2_k127_3108601_0 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 349.0
HFD2_k127_3108601_1 Glycosyltransferases involved in cell wall biogenesis-like protein - - - 0.0000000000000000000000000002926 124.0
HFD2_k127_3123628_0 PFAM 4-hydroxyphenylacetate 3-hydroxylase K00483,K16901 - 1.14.14.8,1.14.14.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004706 590.0
HFD2_k127_3123628_1 Pfam Cupin K00450,K11948 - 1.13.11.38,1.13.11.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007689 343.0
HFD2_k127_3123628_2 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 337.0
HFD2_k127_3123628_3 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000004275 235.0
HFD2_k127_3126427_0 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 2.035e-259 809.0
HFD2_k127_3126427_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004459 318.0
HFD2_k127_3126427_2 response regulator K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000002264 239.0
HFD2_k127_3126427_3 Copper amine oxidase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000002417 198.0
HFD2_k127_3126427_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000002513 178.0
HFD2_k127_3126427_5 PFAM Integrase catalytic region - - - 0.000179 52.0
HFD2_k127_3145260_0 Sulfatase K01130 - 3.1.6.1 3.92e-271 855.0
HFD2_k127_3145260_1 methyltransferase - - - 0.00000000000008366 75.0
HFD2_k127_3145260_2 PFAM DinB family protein - - - 0.000000000005953 66.0
HFD2_k127_3149699_0 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000001139 190.0
HFD2_k127_3149699_1 PFAM N-acetylmuramoyl-L-alanine amidase, family 2 - - - 0.000000000000000000000001849 109.0
HFD2_k127_3163347_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004261 417.0
HFD2_k127_3163347_1 Belongs to the LDH2 MDH2 oxidoreductase family - - - 0.00000000002928 68.0
HFD2_k127_3165222_0 DEAD DEAH box helicase K03654 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 628.0
HFD2_k127_3165222_1 DEAD DEAH box K03724 - - 0.000000000000000000000000000000000000000000000000000000000000009913 219.0
HFD2_k127_3165222_2 F420H(2)-dependent quinone reductase - - - 0.000000000000000000000000000000000000000000000000007882 183.0
HFD2_k127_3165222_3 PFAM Bacterial protein of - - - 0.0000000000000000000001318 112.0
HFD2_k127_3165222_4 - K07071 - - 0.000000000002052 70.0
HFD2_k127_3174099_0 Type ii secretion system protein e K02283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007013 608.0
HFD2_k127_3174099_1 peptidase inhibitor activity K07260 - 3.4.17.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005293 372.0
HFD2_k127_3174099_2 AAA domain K02282,K07705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001401 286.0
HFD2_k127_3174099_3 von Willebrand factor (vWF) type A domain K07114,K12511 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001118 293.0
HFD2_k127_3174099_4 Type II secretion system (T2SS), protein F K02283,K12510 - - 0.0000000000000000000000000000000000000000000000000000003262 205.0
HFD2_k127_3174099_5 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.000000000000000000000000000000000699 141.0
HFD2_k127_3174099_6 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.000000000000000000000000003195 120.0
HFD2_k127_3174099_7 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000004184 108.0
HFD2_k127_3175809_0 Cell division protein FtsA K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004177 430.0
HFD2_k127_3175809_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008203 336.0
HFD2_k127_3175809_2 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003711 271.0
HFD2_k127_3175809_3 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001401 258.0
HFD2_k127_3175809_4 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000006312 138.0
HFD2_k127_3175809_5 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000003096 128.0
HFD2_k127_3175809_6 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins - - - 0.00005899 51.0
HFD2_k127_3190534_0 MMPL family K06994 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 607.0
HFD2_k127_3190534_1 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007674 487.0
HFD2_k127_3190534_10 Redoxin K03564 - 1.11.1.15 0.00000000000000002467 85.0
HFD2_k127_3190534_11 PFAM Uncharacterised BCR, COG1937 K21600 - - 0.0000000000005019 72.0
HFD2_k127_3190534_12 Redoxin - - - 0.000001301 51.0
HFD2_k127_3190534_2 Lipocalin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 313.0
HFD2_k127_3190534_3 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002407 283.0
HFD2_k127_3190534_4 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000000000000000005751 228.0
HFD2_k127_3190534_5 PFAM EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000001554 215.0
HFD2_k127_3190534_6 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000007306 191.0
HFD2_k127_3190534_7 Phosphoglycerate mutase family - - - 0.000000000000000000000000000000000001232 147.0
HFD2_k127_3190534_8 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000005758 148.0
HFD2_k127_3190534_9 NUDIX domain - - - 0.000000000000000000000000000001136 128.0
HFD2_k127_3199765_0 Protein of unknown function (DUF402) K07586,K09145 - - 0.000000000000000000000000000000000003615 150.0
HFD2_k127_3199765_1 CHAD - - - 0.0008371 48.0
HFD2_k127_3216541_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 541.0
HFD2_k127_3216541_1 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009275 422.0
HFD2_k127_3216541_2 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily K00666 - - 0.0000000000000000000000000000000000000000000001432 176.0
HFD2_k127_3216541_3 amp-dependent synthetase and ligase K00666,K16876 - 6.2.1.31 0.0000000000000000000000000000000000000000005834 173.0
HFD2_k127_3216541_4 - - - - 0.000000000000000000004557 102.0
HFD2_k127_3216541_5 conserved protein, contains double-stranded beta-helix domain - - - 0.000000000001433 72.0
HFD2_k127_3216541_6 Redoxin K03564 - 1.11.1.15 0.000000001809 63.0
HFD2_k127_3216541_7 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000017 50.0
HFD2_k127_3218429_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 583.0
HFD2_k127_3218429_1 PFAM thiamine pyrophosphate enzyme-like TPP-binding thiamine pyrophosphate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005524 559.0
HFD2_k127_3218429_2 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004018 423.0
HFD2_k127_3218429_3 PFAM Integrase core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002753 264.0
HFD2_k127_3218429_4 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000001794 222.0
HFD2_k127_3218429_5 DJ-1/PfpI family - - - 0.0000000000000000000000000000000000000000005871 164.0
HFD2_k127_3218429_6 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000005288 165.0
HFD2_k127_3218429_7 F420H(2)-dependent quinone reductase - - - 0.0007388 49.0
HFD2_k127_3224468_0 alcohol dehydrogenase K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000005052 204.0
HFD2_k127_3269840_0 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000678 250.0
HFD2_k127_3274477_0 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 403.0
HFD2_k127_3274477_1 carnitine dehydratase - - - 0.0000000000000000000000000000000000000000000000007459 183.0
HFD2_k127_3274477_2 AraC-like ligand binding domain - - - 0.00000000000000000000000000001938 123.0
HFD2_k127_3274477_3 NAD dependent epimerase/dehydratase family K00059,K07535 - 1.1.1.100 0.0002345 49.0
HFD2_k127_3276048_0 CoA-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004671 344.0
HFD2_k127_3276048_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000001439 144.0
HFD2_k127_3276048_2 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000003009 57.0
HFD2_k127_3276808_0 Cation transporter/ATPase, N-terminus K01531,K12955 - 3.6.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004346 441.0
HFD2_k127_3276808_1 - K00368,K18683 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.7.2.1 0.00000000006658 69.0
HFD2_k127_3280585_0 Phosphoenolpyruvate phosphomutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 387.0
HFD2_k127_3280585_1 Acetyl xylan esterase (AXE1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005155 313.0
HFD2_k127_3280585_2 TIGRFAM 3-oxoacid CoA-transferase, B subunit K01027,K01029,K01032 GO:0001666,GO:0006950,GO:0008150,GO:0009628,GO:0036293,GO:0050896,GO:0070482 2.8.3.5,2.8.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000002207 264.0
HFD2_k127_3280585_3 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005677 262.0
HFD2_k127_3280585_4 cephalosporin-C deacetylase activity K01060 - 3.1.1.41 0.000000000000000000000000000000000000000000000000000000000000000002052 237.0
HFD2_k127_3280585_5 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000004584 184.0
HFD2_k127_3280585_6 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.0000000000000000000000000000000000000000002087 162.0
HFD2_k127_3280585_7 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 0.000000000000000000004677 99.0
HFD2_k127_3283932_0 ATPase activity K02052,K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 391.0
HFD2_k127_3283932_1 ABC transporter permease K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 396.0
HFD2_k127_3283932_2 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006497 356.0
HFD2_k127_3283932_3 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 310.0
HFD2_k127_3283932_4 3-beta hydroxysteroid dehydrogenase/isomerase family K01710,K08678 - 4.1.1.35,4.2.1.46 0.000000000000000000000000000001413 121.0
HFD2_k127_3283932_5 Beta-lactamase superfamily domain - - - 0.0000000000000000000001071 109.0
HFD2_k127_3283932_6 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0005621 42.0
HFD2_k127_3286871_0 Glycosyl hydrolases family 15 - - - 0.0 1074.0
HFD2_k127_3286871_1 PFAM Integrase catalytic region - - - 0.00001602 51.0
HFD2_k127_3291107_0 PFAM Integrase catalytic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002887 413.0
HFD2_k127_3291107_1 COG1484 DNA replication protein - - - 0.0000000000000000000000000000000000000000000000000000000000007417 219.0
HFD2_k127_3291773_0 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 355.0
HFD2_k127_3291773_1 PFAM transglutaminase domain protein - - - 0.00000000000000000000000000000000000000000000000000000003079 216.0
HFD2_k127_3291773_2 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000003923 160.0
HFD2_k127_3291773_3 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0003987 44.0
HFD2_k127_3298027_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 336.0
HFD2_k127_3300190_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000004795 244.0
HFD2_k127_3300190_1 Cytidine and deoxycytidylate deaminase zinc-binding region K01489 - 3.5.4.5 0.000000000000000000000000000000003996 132.0
HFD2_k127_3300190_2 PFAM ABC transporter related K01996 - - 0.000000000000000000002303 96.0
HFD2_k127_3306932_0 Efflux ABC transporter permease protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 401.0
HFD2_k127_3306932_1 Cupin domain K00450 - 1.13.11.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009421 365.0
HFD2_k127_3306932_10 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000004272 161.0
HFD2_k127_3306932_11 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000001234 164.0
HFD2_k127_3306932_12 PFAM secretion protein HlyD family protein K02005 - - 0.000000000000000000000000000000000000001037 170.0
HFD2_k127_3306932_13 Pfam:Methyltransf_6 K10218 - 4.1.3.17 0.00000000000000000000000000000000000009236 149.0
HFD2_k127_3306932_14 - - - - 0.0001143 54.0
HFD2_k127_3306932_2 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 299.0
HFD2_k127_3306932_3 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004042 267.0
HFD2_k127_3306932_4 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002297 270.0
HFD2_k127_3306932_5 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003496 265.0
HFD2_k127_3306932_6 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000002021 246.0
HFD2_k127_3306932_7 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07653 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000001162 244.0
HFD2_k127_3306932_8 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000001363 235.0
HFD2_k127_3306932_9 FAD dependent oxidoreductase K00285,K03153 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0036094,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043436,GO:0043799,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0072527,GO:0072528,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.4.3.19,1.4.5.1 0.00000000000000000000000000000000000000000000001758 185.0
HFD2_k127_3315026_0 alpha/beta hydrolase fold K01561 - 3.8.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008185 394.0
HFD2_k127_3315026_1 NMT1-like family K02051 - - 0.0000000000000000000000000000000000003346 153.0
HFD2_k127_3317912_0 Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides K03478 - 3.5.1.105 0.0000000000000000000000000000000000000000000000001856 191.0
HFD2_k127_3317912_1 Methyltransferase domain K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000002305 122.0
HFD2_k127_3317912_2 Glycosyl transferase family 2 - - - 0.0000000000000000000000008869 113.0
HFD2_k127_3324346_0 VWA domain containing CoxE-like protein K07161 - - 0.0000000000000000000000000000000000000000000000000000000000000000002376 236.0
HFD2_k127_3324346_1 XdhC and CoxI family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000002202 220.0
HFD2_k127_3324346_2 'Molybdopterin - - - 0.000000000000000000000000000000000000000000000000000000001939 216.0
HFD2_k127_3324346_3 NUDIX domain - - - 0.00000000000000000000000000000000000000000000000785 179.0
HFD2_k127_3324346_4 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.00000000000000000000000000000000000000000000008967 176.0
HFD2_k127_3324346_5 XdhC and CoxI family - - - 0.0000000000000000000000000000000000005328 142.0
HFD2_k127_3324346_6 OPT oligopeptide transporter protein - - - 0.0000000000000000000000002034 122.0
HFD2_k127_3325913_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007332 448.0
HFD2_k127_3325913_1 TRAP transporter, solute receptor (TAXI family K07080 - - 0.0000000000000000000001248 109.0
HFD2_k127_332717_0 Asparagine synthase K01953 - 6.3.5.4 1.2e-249 785.0
HFD2_k127_332717_1 ATP-NAD kinase - - - 0.0000000000000000000000000000000000008003 142.0
HFD2_k127_332717_2 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.00001591 47.0
HFD2_k127_3334620_0 Belongs to the mandelate racemase muconate lactonizing enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006509 335.0
HFD2_k127_3334620_1 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K01607 - 4.1.1.44 0.000000000000000000148 91.0
HFD2_k127_3349547_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.611e-233 736.0
HFD2_k127_3349547_1 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 346.0
HFD2_k127_3351714_0 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.00000000000000000000000000008355 119.0
HFD2_k127_3351714_1 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000000000000000005898 101.0
HFD2_k127_3351714_2 SMI1 / KNR4 family - - - 0.000000000000000000002643 96.0
HFD2_k127_3351714_3 acetyltransferase - - - 0.000000000000004375 82.0
HFD2_k127_3351714_4 Domain of unknown function (DU1801) - - - 0.0000000000824 64.0
HFD2_k127_3354326_0 60Kd inner membrane protein K03217 - - 0.0000000000000000000000000000000000000001499 162.0
HFD2_k127_3354326_1 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000004638 107.0
HFD2_k127_3354326_2 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000000001079 78.0
HFD2_k127_3354326_3 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000007259 53.0
HFD2_k127_3354326_4 PFAM single-stranded nucleic acid binding R3H domain protein K06346 - - 0.0000003782 60.0
HFD2_k127_3379059_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009502 441.0
HFD2_k127_3379059_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002299 256.0
HFD2_k127_3379059_2 regulation of cobalamin metabolic process K11390 GO:0000287,GO:0003674,GO:0003824,GO:0004474,GO:0005488,GO:0008150,GO:0009987,GO:0016043,GO:0016740,GO:0016746,GO:0016829,GO:0016830,GO:0016833,GO:0019222,GO:0022607,GO:0030656,GO:0031323,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0046872,GO:0046912,GO:0047777,GO:0050789,GO:0050794,GO:0051171,GO:0051193,GO:0051259,GO:0051260,GO:0062012,GO:0065003,GO:0065007,GO:0070206,GO:0070207,GO:0071840,GO:0106064,GO:1901401 - 0.00000000000000000000000000000000000000000000000000000001071 209.0
HFD2_k127_3379059_3 - K11477 - - 0.0000000000000000000001629 106.0
HFD2_k127_3385976_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.904e-284 913.0
HFD2_k127_3385976_1 PFAM sugar transferase K03606,K20997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 372.0
HFD2_k127_3385976_2 beta-glucosidase activity K05350,K21000 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 337.0
HFD2_k127_3385976_3 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008776 315.0
HFD2_k127_3385976_4 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000004104 271.0
HFD2_k127_3385976_5 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000006088 214.0
HFD2_k127_3385976_6 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000002796 183.0
HFD2_k127_3385976_7 Belongs to the UPF0255 family - - - 0.00000000000000000000000000000000000000000001407 176.0
HFD2_k127_3385976_8 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000007931 158.0
HFD2_k127_3394263_0 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 302.0
HFD2_k127_3394263_1 metal-dependent hydrolase of the TIM-barrel fold K03392,K22213 - 4.1.1.45,4.1.1.52 0.00000000000000000000000000000000000000000000000000000000000003023 228.0
HFD2_k127_3394263_2 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000003869 223.0
HFD2_k127_3394263_3 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000005398 197.0
HFD2_k127_3394263_4 amidohydrolase K15358 - 3.5.2.18 0.000222 48.0
HFD2_k127_3407035_0 Thiamine pyrophosphate enzyme, central domain K03336 - 3.7.1.22 2.255e-272 846.0
HFD2_k127_3407035_1 Xylose isomerase-like TIM barrel K03335 - 4.2.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 395.0
HFD2_k127_3407035_2 Pyridoxamine 5'-phosphate oxidase-related FMN-binding protein - - - 0.0000000000000000000000000006543 121.0
HFD2_k127_3407035_3 Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB K07677 - 2.7.13.3 0.0001992 49.0
HFD2_k127_3423591_0 Transketolase, C-terminal domain K00162 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 518.0
HFD2_k127_3423591_1 PFAM Transketolase central region K00162,K11381,K21417 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 456.0
HFD2_k127_3423591_2 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627,K00658 - 2.3.1.12,2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009943 353.0
HFD2_k127_3429182_0 DNA-directed DNA polymerase K02337 - 2.7.7.7 8.358e-205 656.0
HFD2_k127_3429182_1 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 466.0
HFD2_k127_3429182_10 Male sterility protein K01784 - 5.1.3.2 0.0000000000000000007227 89.0
HFD2_k127_3429182_2 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000001786 264.0
HFD2_k127_3429182_3 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000006337 239.0
HFD2_k127_3429182_4 Helix-hairpin-helix motif K02337,K14162 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000001834 216.0
HFD2_k127_3429182_5 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000127 167.0
HFD2_k127_3429182_6 histidine kinase HAMP region domain protein - - - 0.0000000000000000000000000000000002498 151.0
HFD2_k127_3429182_7 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.000000000000000000000000000006833 120.0
HFD2_k127_3429182_8 phosphatase activity K07025,K08723,K20862 - 3.1.3.102,3.1.3.104,3.1.3.5 0.000000000000000000000000000008057 132.0
HFD2_k127_3429182_9 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000678 108.0
HFD2_k127_347008_0 NAD(P)-binding Rossmann-like domain K00303 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000004996 262.0
HFD2_k127_347008_1 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000002925 214.0
HFD2_k127_3485145_0 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483 - 1.14.14.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009135 459.0
HFD2_k127_3485145_1 cation efflux K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009759 299.0
HFD2_k127_3485145_2 PFAM glycoside hydrolase family 39 - - - 0.00000000000000000000000000000000000000000000000003536 197.0
HFD2_k127_3485145_3 Protein of unknown function (DUF421) - - - 0.00000000000000000000000000000000000000000001838 168.0
HFD2_k127_3485145_4 Polysaccharide deacetylase - - - 0.0000000000000000000004411 106.0
HFD2_k127_3485145_5 Oxidoreductase family, NAD-binding Rossmann fold K00010 - 1.1.1.18,1.1.1.369 0.00000000008417 63.0
HFD2_k127_3485145_6 - - - - 0.0008134 46.0
HFD2_k127_3490283_0 phosphoenolpyruvate carboxykinase (ATP) activity K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000413 304.0
HFD2_k127_3490283_1 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000003579 147.0
HFD2_k127_3490283_2 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000003847 62.0
HFD2_k127_3494365_0 ThiF family K03148,K03636,K21029,K21147 - 2.7.7.73,2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 472.0
HFD2_k127_3494365_1 Pyridoxal-phosphate dependent enzyme K01883,K12339,K21148 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.113,2.5.1.47,6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000001142 249.0
HFD2_k127_3494365_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000002397 238.0
HFD2_k127_3494365_3 TIGRFAM MoaD family protein K03636 GO:0000096,GO:0000097,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.00000000000000000000000003786 112.0
HFD2_k127_3504657_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005731 596.0
HFD2_k127_3504657_1 adenosylhomocysteinase activity K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 588.0
HFD2_k127_3504657_2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835,K01840 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 516.0
HFD2_k127_3504657_3 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772,K03783 - 2.4.2.1,2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005328 365.0
HFD2_k127_3504657_4 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 355.0
HFD2_k127_3504657_5 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 312.0
HFD2_k127_3504657_6 PFAM NAD-dependent epimerase dehydratase K15856 - 1.1.1.281 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007893 300.0
HFD2_k127_3504657_7 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000003008 167.0
HFD2_k127_3504657_8 PFAM zinc finger, SWIM domain protein - - - 0.00000000000000000000001632 105.0
HFD2_k127_3515639_0 amino acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 439.0
HFD2_k127_3515639_1 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004593 386.0
HFD2_k127_3516169_0 PFAM Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 413.0
HFD2_k127_3516169_1 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002883 289.0
HFD2_k127_3516169_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000001621 251.0
HFD2_k127_3516169_3 Enoyl-CoA hydratase/isomerase K15866,K18474 GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006635,GO:0006636,GO:0008150,GO:0008152,GO:0008610,GO:0009056,GO:0009058,GO:0009062,GO:0009987,GO:0016042,GO:0016053,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016860,GO:0016863,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0033559,GO:0034017,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:0072330,GO:1901575,GO:1901576 5.3.3.14,5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000001461 222.0
HFD2_k127_3516169_4 Major facilitator superfamily - - - 0.00000000000000000000000000000000007572 148.0
HFD2_k127_3522193_0 PFAM alpha-2-macroglobulin domain protein K06894 - - 4.54e-232 778.0
HFD2_k127_3522193_1 Belongs to the glutaminase family K01425 - 3.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005027 429.0
HFD2_k127_3522193_2 PFAM CobQ CobB MinD ParA nucleotide binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001104 248.0
HFD2_k127_3524975_0 Multicopper oxidase K00368 - 1.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006657 445.0
HFD2_k127_3524975_1 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 423.0
HFD2_k127_3524975_2 histidine kinase dimerisation and phosphoacceptor region K03406,K07673,K07675 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 304.0
HFD2_k127_3524975_3 Two component transcriptional regulator, LuxR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001609 274.0
HFD2_k127_3524975_4 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000001566 194.0
HFD2_k127_3524975_5 Protein of unknown function (DUF433) - - - 0.00000000000000000000001492 104.0
HFD2_k127_3524975_6 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000003545 72.0
HFD2_k127_3524975_7 PFAM MaoC like domain - - - 0.000003942 55.0
HFD2_k127_3549376_0 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000000001091 153.0
HFD2_k127_3549376_1 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000003607 138.0
HFD2_k127_3549376_2 cytokinin biosynthetic process K06966 - 3.2.2.10 0.00000000000000000000000001335 116.0
HFD2_k127_3549376_3 Acetyltransferase (GNAT) domain - - - 0.00000009573 56.0
HFD2_k127_3549376_4 transferase activity, transferring acyl groups K14658,K15520 - 2.3.1.189 0.00000009685 55.0
HFD2_k127_3550840_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000002006 232.0
HFD2_k127_3550840_1 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000002017 216.0
HFD2_k127_3550840_2 Hit family K19710 - 2.7.7.53 0.0000000000000000000000000000000000000000000000000000001556 201.0
HFD2_k127_3550840_3 Glutaredoxin - - - 0.00000000000001068 76.0
HFD2_k127_3550840_4 Methyltransferase domain - - - 0.000000000533 64.0
HFD2_k127_3580496_0 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000002349 184.0
HFD2_k127_3583129_0 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 336.0
HFD2_k127_3583129_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 325.0
HFD2_k127_3588034_0 histidine kinase, dimerisation and phosphoacceptor region - - - 0.0000000000000000000000000000000000000000000002936 187.0
HFD2_k127_3590827_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000002098 138.0
HFD2_k127_3603154_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005956 479.0
HFD2_k127_3603154_1 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K02337,K14162 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 477.0
HFD2_k127_3606478_0 Oxidoreductase K13327 - 1.1.1.384 0.00000000000000304 80.0
HFD2_k127_3606478_1 Glycosyltransferase family 87 - - - 0.000000000000009124 87.0
HFD2_k127_3606515_0 Putative restriction endonuclease - - - 0.000000000000000000000000000000000000000000000000009276 188.0
HFD2_k127_3606515_1 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway K03707 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 3.5.99.2 0.00000000000000000000000000000000000002112 157.0
HFD2_k127_3606515_2 monooxygenase - - - 0.00000000000000000000000009562 108.0
HFD2_k127_3606515_3 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K06989 - 1.4.1.21 0.0000004229 57.0
HFD2_k127_3607680_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000097 292.0
HFD2_k127_3609545_0 Catalyzes the formation of 3-methyl-2-oxobutanoate from 2,3,-dihydroxy-3-methylbutanoate - - - 4.567e-233 733.0
HFD2_k127_3609545_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007451 386.0
HFD2_k127_3609545_2 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 325.0
HFD2_k127_3609545_3 Peroxiredoxin K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000002852 178.0
HFD2_k127_3609545_4 TatD family K03424 - - 0.00000000000000000000000000001247 128.0
HFD2_k127_3610204_0 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001857 285.0
HFD2_k127_3610365_0 Amidase K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004862 477.0
HFD2_k127_3610365_1 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000002341 203.0
HFD2_k127_3610365_2 Methionine biosynthesis protein MetW - - - 0.000000000000000001895 94.0
HFD2_k127_3610365_3 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000001239 75.0
HFD2_k127_3610365_4 GHKL domain K07641 - 2.7.13.3 0.0001028 45.0
HFD2_k127_3611550_0 Acetamidase formamidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008199 323.0
HFD2_k127_3615475_0 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000001442 234.0
HFD2_k127_3615475_1 Sigma-70 region 2 - - - 0.000000000000000000000000000000000000006494 153.0
HFD2_k127_3615475_2 peroxiredoxin activity K03564 - 1.11.1.15 0.000000000000000000000000000936 123.0
HFD2_k127_3615475_3 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000531 113.0
HFD2_k127_3615475_5 Zinc finger RNA binding protein 2 K13203 GO:0000375,GO:0000377,GO:0000398,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 - 0.00000748 52.0
HFD2_k127_3617702_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009055,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0022900,GO:0030312,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046429,GO:0046490,GO:0046872,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0052592,GO:0055114,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000002274 232.0
HFD2_k127_3617702_1 Two component transcriptional regulator, winged helix family K07658 - - 0.000000000000000000000000000000000000000000000000002532 190.0
HFD2_k127_3617702_2 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.00000000000000000000000002271 111.0
HFD2_k127_36400_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 1.264e-316 984.0
HFD2_k127_36400_1 Domain of unknown function (DUF3459) K01236 - 3.2.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 355.0
HFD2_k127_36400_2 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000007314 233.0
HFD2_k127_3641305_0 glycogen debranching - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 579.0
HFD2_k127_3641305_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 542.0
HFD2_k127_3641305_2 Belongs to the enoyl-CoA hydratase isomerase family K07546,K08299,K15866 - 4.2.1.149,5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 295.0
HFD2_k127_3641305_3 EVE domain - - - 0.00000000000000000000000000000000001249 140.0
HFD2_k127_3641305_4 Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - 0.00000000000000000000000000000000003231 137.0
HFD2_k127_3647466_0 - - - - 0.000000000000000000000000000000000000000000000002687 178.0
HFD2_k127_3647466_1 domain protein K01212,K01317,K12287,K20276 - 3.2.1.65,3.4.21.10 0.0000000002767 73.0
HFD2_k127_3647466_2 Belongs to the glycosyl hydrolase 26 family - - - 0.000006441 59.0
HFD2_k127_3653436_0 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002231 460.0
HFD2_k127_3653436_1 RNA polymerase sigma-54 factor K03092 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0042802,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000409 406.0
HFD2_k127_3653436_2 Transmembrane secretion effector K08225 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005169 326.0
HFD2_k127_3653436_3 Cytochrome D1 heme domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 304.0
HFD2_k127_3653436_4 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000001619 196.0
HFD2_k127_3653436_5 lipid kinase activity - - - 0.00000000000000000000000000000000000000001116 166.0
HFD2_k127_3653436_6 Transglycosylase associated protein - - - 0.000000000000004068 77.0
HFD2_k127_3667720_0 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005242 533.0
HFD2_k127_3667720_1 HlyD family secretion protein K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 515.0
HFD2_k127_3670951_0 Belongs to the argininosuccinate synthase family. Type K01940 - 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006309 554.0
HFD2_k127_3670951_1 Threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 344.0
HFD2_k127_3680777_0 Zincin-like metallopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008073 293.0
HFD2_k127_3680777_1 - - - - 0.00000000000000000000000000000000000000007624 158.0
HFD2_k127_3680777_2 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000009817 75.0
HFD2_k127_3680777_3 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000005879 59.0
HFD2_k127_3680777_4 Recombinase zinc beta ribbon domain - - - 0.0003797 46.0
HFD2_k127_3681425_0 Putative pyruvate format-lyase activating enzyme (DUF1786) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000308 383.0
HFD2_k127_3681425_1 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 306.0
HFD2_k127_3681425_2 organic phosphonate transmembrane transporter activity K02042 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006802 292.0
HFD2_k127_3681425_3 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001262 280.0
HFD2_k127_3681425_4 ABC-type phosphate phosphonate transport system periplasmic component K02044 - - 0.000000000000000000000000000000000000000000000000000000000000000000007692 248.0
HFD2_k127_3681425_5 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000001817 225.0
HFD2_k127_3681425_6 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000003018 195.0
HFD2_k127_3681425_7 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000005442 186.0
HFD2_k127_3681425_8 Bacterial protein of unknown function (DUF951) - - - 0.0000000000000000002832 94.0
HFD2_k127_3681425_9 S-adenosylmethionine decarboxylase K01611 - 4.1.1.50 0.0009163 43.0
HFD2_k127_3682201_0 PFAM FAD linked oxidase domain protein K00102,K00104 - 1.1.2.4,1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 561.0
HFD2_k127_3682201_1 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 351.0
HFD2_k127_3682201_2 FAD binding domain K11472 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004601 284.0
HFD2_k127_3682201_3 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000004971 166.0
HFD2_k127_3682201_4 thiamine biosynthesis protein ThiS K03154 - - 0.000000000000002905 77.0
HFD2_k127_3691037_0 Phage tail sheath C-terminal domain K06907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 595.0
HFD2_k127_3691037_1 Phage tail sheath protein subtilisin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006798 317.0
HFD2_k127_3691037_2 Protein of unknown function (DUF4255) - - - 0.000000000000000000000000000000000000000000000000007817 187.0
HFD2_k127_3691037_3 T4-like virus tail tube protein gp19 - - - 0.000000000000000000000000000000000000000000001158 169.0
HFD2_k127_3691037_4 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000006456 155.0
HFD2_k127_3691037_5 - - - - 0.00000000000000000000000000000005072 137.0
HFD2_k127_3691037_6 - - - - 0.0000001729 57.0
HFD2_k127_3693941_0 FCD K05799 - - 0.0000000000000000000000000000000000000000000002285 175.0
HFD2_k127_3693941_1 PFAM oxidoreductase, molybdopterin binding - - - 0.0000000000000000000000000000000000000001629 154.0
HFD2_k127_3693941_2 PFAM PKD domain containing protein - - - 0.000000000000000000000002221 115.0
HFD2_k127_3701141_0 PFAM 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000001623 252.0
HFD2_k127_3701141_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000001153 184.0
HFD2_k127_3707622_0 Dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 325.0
HFD2_k127_3707622_1 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000001513 271.0
HFD2_k127_3707622_2 lactoylglutathione lyase activity - - - 0.000000000000000002443 87.0
HFD2_k127_3714060_0 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 394.0
HFD2_k127_3714060_1 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000379 230.0
HFD2_k127_3714060_2 Cytochrome c - - - 0.0000000000000000001025 96.0
HFD2_k127_3719165_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00647,K09458 - 2.3.1.179,2.3.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007183 513.0
HFD2_k127_3719165_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008063 513.0
HFD2_k127_3719165_2 Tartrate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 458.0
HFD2_k127_3719165_3 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 406.0
HFD2_k127_3719165_4 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003625 379.0
HFD2_k127_3719165_5 - - - - 0.0000000000000000000000000000000000003255 147.0
HFD2_k127_3719165_6 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000399 93.0
HFD2_k127_3719165_7 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000006113 76.0
HFD2_k127_371999_0 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000004449 261.0
HFD2_k127_371999_1 ATP-dependent DNA helicase activity K01144,K07464,K16898 - 3.1.11.5,3.1.12.1,3.6.4.12 0.0000000000000000000000000000005655 129.0
HFD2_k127_3720682_0 Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000403 398.0
HFD2_k127_3720682_1 Sodium/calcium exchanger protein K07300 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 321.0
HFD2_k127_3720682_2 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway K03707 - 3.5.99.2 0.00000000000000000000000000000000000000000000000000000000000000000002798 239.0
HFD2_k127_3720682_3 Belongs to the peptidase M16 family - - - 0.000000000000000000000000000000000000000000000009484 188.0
HFD2_k127_3720682_4 CHASE3 domain - - - 0.00000000000000000000000000000000000000000008874 177.0
HFD2_k127_3720682_5 Belongs to the peptidase M16 family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000005551 175.0
HFD2_k127_3720682_6 PFAM response regulator receiver K02483,K07658,K07668 - - 0.00000000000000000000000002006 117.0
HFD2_k127_3720682_7 Belongs to the Nudix hydrolase family K18445 - 3.6.1.61 0.00000000000008792 76.0
HFD2_k127_3723820_0 ABC transporter K01990,K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008681 321.0
HFD2_k127_3723820_1 Abc-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000007179 228.0
HFD2_k127_3723820_2 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000006791 113.0
HFD2_k127_3727346_0 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 299.0
HFD2_k127_3727346_1 Belongs to the 'phage' integrase family - - - 0.0000000000000000001528 90.0
HFD2_k127_3727346_2 - - - - 0.000000008114 61.0
HFD2_k127_3727346_3 - - - - 0.00002133 50.0
HFD2_k127_3730393_0 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 437.0
HFD2_k127_3730393_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000009366 239.0
HFD2_k127_3730393_2 PAS fold - - - 0.000000000000000000000000000000000000000000000000000004205 214.0
HFD2_k127_3730393_3 Helix-hairpin-helix domain K02347 - - 0.000000000000000000000000000000000000000000000000000005786 199.0
HFD2_k127_3730393_4 Peptidase M28 - - - 0.00000000000000000000000000000000000000000000000000002147 203.0
HFD2_k127_3730393_5 - - - - 0.0000000000000000000000000000001269 137.0
HFD2_k127_3730393_6 PFAM Succinylglutamate desuccinylase Aspartoacylase K06987 - - 0.0000000000000000000000000007585 127.0
HFD2_k127_3730393_7 cheY-homologous receiver domain - - - 0.000000000000000000002883 109.0
HFD2_k127_3730393_8 Cysteine-rich secretory protein family - - - 0.0000000000000000001425 97.0
HFD2_k127_3730393_9 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000003308 80.0
HFD2_k127_3730797_0 PFAM Cytochrome C assembly protein K02198 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 287.0
HFD2_k127_3730797_1 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.0000000000000000000000000000000000000000000000001605 185.0
HFD2_k127_3730797_2 periplasmic protein thiol disulfide oxidoreductases, DsbE subfamily K02199 - - 0.000000000000000000000000000000000002059 145.0
HFD2_k127_3730797_3 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000002012 101.0
HFD2_k127_3730797_4 - - - - 0.000007556 53.0
HFD2_k127_3733203_0 Glycosyl transferase 4-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 362.0
HFD2_k127_3734080_0 Belongs to the citrate synthase family K01647 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 487.0
HFD2_k127_3734080_1 Helix-turn-helix domain K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 424.0
HFD2_k127_3738949_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008489 286.0
HFD2_k127_3738949_1 MGS-like domain K01734 - 4.2.3.3 0.000000000000000000000000000000000000000000000006241 175.0
HFD2_k127_3741657_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058,K16843 - 1.1.1.310,1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 454.0
HFD2_k127_3741657_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 435.0
HFD2_k127_3741657_2 Aminotransferase class-V K00436 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 374.0
HFD2_k127_3741657_3 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005477 341.0
HFD2_k127_3741657_4 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000002957 117.0
HFD2_k127_3741657_5 Tetratricopeptide repeat - - - 0.00000000000000001488 96.0
HFD2_k127_3753886_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 348.0
HFD2_k127_3753886_1 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 320.0
HFD2_k127_3753886_2 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000005134 184.0
HFD2_k127_3753886_3 - - - - 0.0000000000000000000000000002708 119.0
HFD2_k127_3754894_0 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000005752 226.0
HFD2_k127_3754894_1 protein histidine kinase activity K07651,K07711 - 2.7.13.3 0.000000000000000000000000000000000000000000000000003245 193.0
HFD2_k127_3776873_0 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003693 543.0
HFD2_k127_3776873_1 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009849 399.0
HFD2_k127_3776873_2 PFAM Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004433 355.0
HFD2_k127_3776873_3 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 361.0
HFD2_k127_3776873_4 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000207 91.0
HFD2_k127_3776873_5 protein conserved in cyanobacteria - - - 0.00000000000003819 79.0
HFD2_k127_3776873_6 Putative restriction endonuclease - - - 0.00004328 51.0
HFD2_k127_3780109_0 Multicopper oxidase K00368,K22348 - 1.16.3.3,1.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008049 492.0
HFD2_k127_3780109_1 Di-haem oxidoreductase, putative peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001996 255.0
HFD2_k127_3780109_2 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000001095 204.0
HFD2_k127_3780109_3 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.00002116 50.0
HFD2_k127_3780109_4 PFAM NUDIX hydrolase K01823 - 5.3.3.2 0.0005731 50.0
HFD2_k127_3800141_0 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000000000000000000004655 229.0
HFD2_k127_3800141_1 4-amino-4-deoxy-L-arabinose transferase activity K14340 - - 0.0000000000000000002063 102.0
HFD2_k127_3810853_0 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 321.0
HFD2_k127_3810853_1 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002057 292.0
HFD2_k127_3810853_2 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000000000006877 214.0
HFD2_k127_3810853_3 Gamma-glutamyltranspeptidase - - - 0.0000000000000000000000000000000000006671 142.0
HFD2_k127_3810853_4 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000001095 142.0
HFD2_k127_3810853_5 TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED - - - 0.00000000000000000000000008759 118.0
HFD2_k127_3810853_6 Acetolactate synthase K01652 - 2.2.1.6 0.000000005262 59.0
HFD2_k127_3812551_0 Asp Glu hydantoin racemase - - - 0.00000000000000000000000000000000000003855 151.0
HFD2_k127_3825122_0 - - - - 0.00000000002358 67.0
HFD2_k127_3825122_1 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000005511 66.0
HFD2_k127_3825122_2 Protein of unknown function (DUF4012) - - - 0.00000002118 64.0
HFD2_k127_382565_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 330.0
HFD2_k127_382565_1 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000001094 252.0
HFD2_k127_382565_2 Response regulator receiver domain protein - - - 0.00000000000001467 84.0
HFD2_k127_3832828_0 AMP-binding enzyme K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004624 346.0
HFD2_k127_3832828_1 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000009085 84.0
HFD2_k127_3837311_0 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006242 416.0
HFD2_k127_3837311_1 Glycosyl hydrolase family 36 C-terminal domain K07407 - 3.2.1.22 0.00000000000000000000002391 114.0
HFD2_k127_3837854_0 PFAM acyl-CoA dehydrogenase domain protein K00255,K11731 - 1.3.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 501.0
HFD2_k127_3837854_1 Acyl- CoA dehydrogenase type 2 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008387 404.0
HFD2_k127_3837854_2 Succinyl-CoA ligase like flavodoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 376.0
HFD2_k127_3837854_3 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 301.0
HFD2_k127_3839429_0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K09459 - 4.1.1.82 0.000000000000000000000000000002724 126.0
HFD2_k127_384022_0 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 562.0
HFD2_k127_384022_2 PFAM ThiJ PfpI domain protein - - - 0.0000168 47.0
HFD2_k127_3841382_0 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 317.0
HFD2_k127_3841382_1 Predicted membrane protein (DUF2079) - - - 0.000000000000000000000000000000000000000000000000000000125 220.0
HFD2_k127_3841382_2 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000001774 203.0
HFD2_k127_3841382_3 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.000000000000000000000000000000000007227 146.0
HFD2_k127_3846752_0 - - - - 0.0000000000000000000000000000000000000000000000001048 192.0
HFD2_k127_3846752_1 PFAM sigma-70 region 2 domain protein K03088 - - 0.000000000000000000000000000000000000000000001141 172.0
HFD2_k127_3846752_2 Anti-sigma-K factor rskA - - - 0.0001486 49.0
HFD2_k127_3847369_0 TIGRFAM DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000005593 213.0
HFD2_k127_3847369_1 PFAM SMC domain protein K03546 - - 0.00000000000000000000000007261 108.0
HFD2_k127_3847369_2 Phospholipid-binding domain protein - - - 0.000000006767 65.0
HFD2_k127_385896_0 synthase K00705,K06044 GO:0000272,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009251,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016052,GO:0016853,GO:0016866,GO:0030978,GO:0030980,GO:0034637,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0047470,GO:0071704,GO:1901575,GO:1901576 2.4.1.25,5.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 556.0
HFD2_k127_385896_1 Glycosyl hydrolases family 15 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006525 522.0
HFD2_k127_3860600_0 Dehydrogenase E1 component K00166 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008007 314.0
HFD2_k127_3860600_1 Enoyl-(Acyl carrier protein) reductase K03366 - 1.1.1.304,1.1.1.76 0.0000000000000000000000000000000000000000000000000000000000000000002844 239.0
HFD2_k127_3860600_2 Enoyl-(Acyl carrier protein) reductase K00059,K03366 - 1.1.1.100,1.1.1.304,1.1.1.76 0.000000000000000000000000000000000000000000000000000000000000000003928 235.0
HFD2_k127_3860600_3 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.0000000000000000000000000000000000000000000000000006925 189.0
HFD2_k127_3860600_4 Belongs to the UPF0173 family - - - 0.000000000000000000000000003812 121.0
HFD2_k127_3860600_5 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000005198 90.0
HFD2_k127_3860600_6 Belongs to the eIF-2B alpha beta delta subunits family - - - 0.00000000000000006636 87.0
HFD2_k127_3860600_7 PFAM NADH flavin oxidoreductase NADH oxidase K00317 - 1.5.8.1,1.5.8.2 0.00000001254 58.0
HFD2_k127_3877210_0 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 400.0
HFD2_k127_3897525_0 methyltransferase - - - 0.0000000000000000000000000000000000000001008 160.0
HFD2_k127_3897525_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000001513 153.0
HFD2_k127_3897525_2 Reductive dehalogenase subunit K21566 - - 0.00000000000000000000000000000008521 141.0
HFD2_k127_3897525_3 Haem-degrading - - - 0.0000000000000109 79.0
HFD2_k127_3899733_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 363.0
HFD2_k127_3899733_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000003444 192.0
HFD2_k127_3899733_2 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03644,K03801 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181,2.8.1.8 0.000000000000000000000000000000004263 140.0
HFD2_k127_3899733_3 C4-dicarboxylate ABC transporter - - - 0.0000000000000000000001279 109.0
HFD2_k127_3899733_4 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000004357 70.0
HFD2_k127_3915135_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 1.148e-211 683.0
HFD2_k127_3915135_1 Fungal trichothecene efflux pump (TRI12) - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006731 535.0
HFD2_k127_3915135_2 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000000000000000000000000000000000000000000002239 235.0
HFD2_k127_3915135_3 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000003352 81.0
HFD2_k127_3917017_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000548 372.0
HFD2_k127_3917017_1 Quinolinate phosphoribosyl transferase, N-terminal domain K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004087 280.0
HFD2_k127_3917017_2 NUDIX domain K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000004396 172.0
HFD2_k127_3917017_3 Highly conserved protein containing a thioredoxin domain - - - 0.00000006802 61.0
HFD2_k127_392144_0 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 430.0
HFD2_k127_392144_1 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006351 380.0
HFD2_k127_392144_2 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000006292 194.0
HFD2_k127_3925309_0 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 331.0
HFD2_k127_3925309_1 DoxX K15977,K16937 - 1.8.5.2 0.000000000000000000000000000000000000000000000000000000009677 204.0
HFD2_k127_3925309_2 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000003349 198.0
HFD2_k127_3925309_3 Belongs to the universal stress protein A family - - - 0.000000000000000000000002359 113.0
HFD2_k127_3925309_4 Short C-terminal domain K08982 - - 0.000002667 54.0
HFD2_k127_3942549_0 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000003627 168.0
HFD2_k127_3942549_1 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000006566 166.0
HFD2_k127_3942549_2 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000006835 167.0
HFD2_k127_3942549_3 Glycosyl transferase 4-like domain K13668 - 2.4.1.346 0.0000000000000000000000000005045 130.0
HFD2_k127_3942549_4 PFAM glycosyl transferase group 1 - - - 0.000000000000003668 80.0
HFD2_k127_3942549_5 Polysaccharide biosynthesis protein - - - 0.0004723 52.0
HFD2_k127_3951654_0 beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 453.0
HFD2_k127_3951654_1 DinB superfamily - - - 0.000000000000000000000000000000000001248 147.0
HFD2_k127_3951654_2 COG3227 Zinc metalloprotease (elastase) K01400,K01401,K19351 GO:0005575,GO:0005576 3.4.24.28,3.4.24.29 0.00006425 55.0
HFD2_k127_3968531_0 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008246 409.0
HFD2_k127_3968531_1 Domain of unknown function (DUF4268) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008868 329.0
HFD2_k127_3996606_0 ATP-binding region, ATPase domain protein K02487,K03407,K06596 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006157 489.0
HFD2_k127_3996606_1 PFAM 5-formyltetrahydrofolate cyclo-ligase K01934 - 6.3.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000001386 250.0
HFD2_k127_3996606_2 Luciferase-like monooxygenase K17228 - 1.14.14.35 0.00000000000000000000000000006018 127.0
HFD2_k127_3996606_3 integral membrane protein - - - 0.000000000000000000000001002 117.0
HFD2_k127_3996606_4 PFAM CheW domain protein K03408 - - 0.0005217 52.0
HFD2_k127_4004891_0 PFAM Exonuclease, RNase T and DNA polymerase III K02342,K03722 - 2.7.7.7,3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 636.0
HFD2_k127_4006175_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00520 - 1.16.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 321.0
HFD2_k127_4006175_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000465 196.0
HFD2_k127_4008412_0 Coenzyme A transferase K01028 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000113 259.0
HFD2_k127_4008412_1 Coenzyme A transferase K01029 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000002451 245.0
HFD2_k127_4008412_2 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000002909 210.0
HFD2_k127_4008412_3 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00015 - 1.1.1.26 0.000000000000000000000000000000000000000008887 158.0
HFD2_k127_4008412_4 PFAM peptidase M16 domain protein - - - 0.0000000000000000000000000000000000002091 155.0
HFD2_k127_4011209_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 293.0
HFD2_k127_4011209_1 COG3335 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003506 274.0
HFD2_k127_4011209_10 DDE superfamily endonuclease - - - 0.0000000000000002013 85.0
HFD2_k127_4011209_11 Copper binding proteins, plastocyanin/azurin family - - - 0.00000000000003183 79.0
HFD2_k127_4011209_12 Belongs to the universal stress protein A family - - - 0.00000000000009095 77.0
HFD2_k127_4011209_2 PAS sensor protein - - - 0.0000000000000000000000000000000000000000000000005266 183.0
HFD2_k127_4011209_3 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000000000002741 172.0
HFD2_k127_4011209_4 Oxidoreductase NAD-binding domain - - - 0.00000000000000000000000000000000000001469 154.0
HFD2_k127_4011209_5 endonuclease III K01247 - 3.2.2.21 0.00000000000000000000000000000000000002356 152.0
HFD2_k127_4011209_6 PFAM transposase, IS4 family protein - - - 0.00000000000000000000000000005874 117.0
HFD2_k127_4011209_7 - K07234 - - 0.000000000000000000000000003084 126.0
HFD2_k127_4011209_8 Cupin 2, conserved barrel domain protein K18991 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009438,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019172,GO:0019243,GO:0019249,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046185,GO:0046394,GO:0051596,GO:0061727,GO:0071704,GO:0072330,GO:1901575,GO:1901576,GO:1901615,GO:1901617 - 0.0000000000000000001034 95.0
HFD2_k127_4011209_9 Bacterial-like globin K06886 - - 0.000000000000000001136 88.0
HFD2_k127_402607_0 AMP-binding enzyme C-terminal domain - - - 2.829e-242 768.0
HFD2_k127_40300_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001469 263.0
HFD2_k127_40300_1 Belongs to the DapA family - - - 0.00000000000000000000000000000000000000000000000000000001304 209.0
HFD2_k127_4030562_0 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 367.0
HFD2_k127_4030562_1 phosphatidylinositol kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005285 253.0
HFD2_k127_4030562_2 Protein of unknown function (DUF664) - - - 0.000000000000000000000000000000000000000000004278 169.0
HFD2_k127_4030562_3 Flagellar filament outer layer protein Flaa - - - 0.00000000000000000000000001622 126.0
HFD2_k127_4030562_4 Nitrile hydratase beta subunit - - - 0.00000000000000000000000587 103.0
HFD2_k127_4032948_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03694,K03695 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 563.0
HFD2_k127_4032948_1 Sigma-70 region 3 K02405 - - 0.0000000000000000000000000000000000000000000000000000000009645 211.0
HFD2_k127_4035407_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006846 348.0
HFD2_k127_4035407_1 Chromate resistance exported protein - - - 0.0000000000000000000000000000000276 133.0
HFD2_k127_4035407_2 PFAM Chromate transporter K07240 - - 0.00000000000000000001017 104.0
HFD2_k127_4035407_3 COG2059 Chromate transport protein ChrA K07240 - - 0.0000001658 62.0
HFD2_k127_4039755_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 518.0
HFD2_k127_4039755_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000003571 110.0
HFD2_k127_4039755_2 Psort location Cytoplasmic, score 9.26 K00334 - 1.6.5.3 0.0001125 48.0
HFD2_k127_4042241_0 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002978 352.0
HFD2_k127_4042241_1 PFAM sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002325 283.0
HFD2_k127_4046633_0 DNA polymerase type-B family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004919 625.0
HFD2_k127_4046633_1 PAC2 family - - - 0.00000000000000000000000000000000000000000000000004354 189.0
HFD2_k127_4046633_2 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000001255 123.0
HFD2_k127_4046633_3 ARD/ARD' family - - - 0.0004737 49.0
HFD2_k127_4051735_0 AP endonuclease family 2 K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000003904 224.0
HFD2_k127_4051735_1 CoA-transferase family III K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000007658 173.0
HFD2_k127_4051735_2 4Fe-4S binding domain - - - 0.000000000000000000000006174 104.0
HFD2_k127_405679_0 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001348 263.0
HFD2_k127_405679_1 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000001515 113.0
HFD2_k127_405679_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00018,K00058 - 1.1.1.29,1.1.1.399,1.1.1.95 0.0000000000000004023 87.0
HFD2_k127_4057598_0 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006721 538.0
HFD2_k127_4057598_1 PHP domain protein - - - 0.000000000000000002574 94.0
HFD2_k127_4057598_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000001984 66.0
HFD2_k127_4059214_0 Fructose-bisphosphate aldolase class-II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006797 490.0
HFD2_k127_4059214_1 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005933 376.0
HFD2_k127_4059214_2 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001218 283.0
HFD2_k127_4059214_3 cyclic nucleotide binding K04739,K10914 - - 0.0000000000000000006507 97.0
HFD2_k127_4060411_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 317.0
HFD2_k127_4060411_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000128 153.0
HFD2_k127_4065739_0 acetyl-coa acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 493.0
HFD2_k127_4065739_1 Amidohydrolase K07045,K14333,K15063,K20941 - 4.1.1.103,4.1.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008121 419.0
HFD2_k127_4065739_2 Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) K00010 - 1.1.1.18,1.1.1.369 0.00000000000000000000000000000000000000000000000000000000000000000000000000001158 269.0
HFD2_k127_4065739_3 helix_turn_helix ASNC type K03719 - - 0.000000000000000000000000000000000000000000002064 169.0
HFD2_k127_4065739_4 Protein of unknown function DUF86 - - - 0.0000000000000000000000000000000000000126 153.0
HFD2_k127_4065739_5 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.0000000000000000000000000004516 119.0
HFD2_k127_4065739_6 nucleotidyltransferase activity K07076 - - 0.00000000000000000000000005449 112.0
HFD2_k127_4065739_7 DinB superfamily - - - 0.00000000000000000000008996 107.0
HFD2_k127_4067824_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000281 425.0
HFD2_k127_4067824_1 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000000006641 187.0
HFD2_k127_4067824_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000005479 132.0
HFD2_k127_4067824_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000005186 58.0
HFD2_k127_4069916_0 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 396.0
HFD2_k127_4069916_1 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000001486 111.0
HFD2_k127_4069916_2 Protein of unknown function (DUF998) - - - 0.000000000000005526 79.0
HFD2_k127_4069916_3 Protein of unknown function (DUF998) - - - 0.00000008574 59.0
HFD2_k127_4070107_0 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000003882 226.0
HFD2_k127_4070107_2 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.0000000000000000000003346 100.0
HFD2_k127_4070107_3 sptr d1c427 - - - 0.00000004199 65.0
HFD2_k127_4076009_0 ABC-type multidrug transport system ATPase and permease K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004968 517.0
HFD2_k127_4076009_1 ABC-type multidrug transport system ATPase and permease K06147 - - 0.000000000000000000000000000001786 133.0
HFD2_k127_4076009_2 Glycosyltransferase like family 2 - - - 0.0000000000000007111 81.0
HFD2_k127_4077030_0 cellulose synthase K00694 - 2.4.1.12 0.0000009807 62.0
HFD2_k127_4101385_0 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005154 280.0
HFD2_k127_4101385_1 transferase activity, transferring glycosyl groups K00694 - 2.4.1.12 0.0000000000000000000000000003887 116.0
HFD2_k127_4112785_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 3.094e-318 997.0
HFD2_k127_4112785_1 succinate-CoA ligase activity K01903 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 373.0
HFD2_k127_4112785_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007747 356.0
HFD2_k127_4112785_3 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 351.0
HFD2_k127_4112785_4 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 336.0
HFD2_k127_4112785_5 PFAM ABC transporter related K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009086 326.0
HFD2_k127_4112785_6 transport system permease K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007392 295.0
HFD2_k127_4112785_7 acr, cog1565 - - - 0.00000000000000000000000000000000000000000000000000000000000000000008121 246.0
HFD2_k127_4112785_8 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000008699 106.0
HFD2_k127_4112785_9 - - - - 0.0000001772 63.0
HFD2_k127_4122531_0 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 304.0
HFD2_k127_4122531_2 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA - - - 0.000000000000000000000000002129 121.0
HFD2_k127_4138703_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009607 377.0
HFD2_k127_4138703_1 Two component transcriptional regulator, winged helix family K07669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 285.0
HFD2_k127_4138703_2 Zinc-binding dehydrogenase K00008,K00060 - 1.1.1.103,1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000001148 269.0
HFD2_k127_4148200_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005035 377.0
HFD2_k127_4148200_1 PFAM basic membrane lipoprotein K07335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 371.0
HFD2_k127_4148200_10 Domain of unknown function (DUF1330) - - - 0.0000000000000000000003314 104.0
HFD2_k127_4148200_11 Flagellar filament outer layer protein Flaa - - - 0.00000000000000000000132 109.0
HFD2_k127_4148200_2 Dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000001386 233.0
HFD2_k127_4148200_3 PFAM ParB domain protein nuclease K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000364 235.0
HFD2_k127_4148200_4 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000001153 220.0
HFD2_k127_4148200_5 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000000009328 211.0
HFD2_k127_4148200_6 myo-inosose-2 dehydratase activity K00457,K06606 - 1.13.11.27,5.3.99.11 0.0000000000000000000000000000000000000000000000000000000008576 210.0
HFD2_k127_4148200_7 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000002323 202.0
HFD2_k127_4148200_8 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain - - - 0.000000000000000000000000000000000000001588 153.0
HFD2_k127_4148200_9 Domain of unknown function (DUF1330) - - - 0.0000000000000000000002427 104.0
HFD2_k127_4156753_0 AAA domain K07028 - - 0.00000000000000000000000000000000000000000000000000000000003727 212.0
HFD2_k127_4156753_1 PFAM UspA domain protein - - - 0.000000000000000000000000000000000000001796 164.0
HFD2_k127_4156753_2 PFAM CBS domain K07182 - - 0.0000000000000000009636 100.0
HFD2_k127_4162278_0 Domain of unknown function (DUF2437) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004364 335.0
HFD2_k127_4162278_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000008979 93.0
HFD2_k127_417967_0 PFAM Major Facilitator Superfamily K08223 - - 0.00000000000000000000000000000000000000000000002897 184.0
HFD2_k127_417967_1 Oxidoreductase molybdopterin binding domain K07147 - - 0.0000000000000000000000000000000000005357 155.0
HFD2_k127_417967_2 Cupin 2, conserved barrel domain protein - - - 0.00000000000000002447 89.0
HFD2_k127_4179827_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 454.0
HFD2_k127_4179827_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000843 434.0
HFD2_k127_4179827_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000006559 112.0
HFD2_k127_4191949_0 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008582 256.0
HFD2_k127_4191949_1 Protein of unknown function (DUF433) - - - 0.000000000000000000000000002479 113.0
HFD2_k127_4191949_2 Mut7-C RNAse domain - - - 0.00000000000000000001393 97.0
HFD2_k127_4191949_3 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.00000376 54.0
HFD2_k127_4191949_4 - - - - 0.00008874 46.0
HFD2_k127_4197215_0 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000004851 177.0
HFD2_k127_4197215_1 Pfam:Pyridox_oxidase - - - 0.0000000000000000000000000000001434 129.0
HFD2_k127_4207153_0 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049,K15555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000504 276.0
HFD2_k127_4207153_1 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000006317 176.0
HFD2_k127_4207153_2 Endoribonuclease L-PSP - - - 0.000000000000000000005952 98.0
HFD2_k127_4207153_3 Glyoxalase-like domain K08234 - - 0.000000003482 59.0
HFD2_k127_4210168_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005324 370.0
HFD2_k127_4212452_0 Replication protein C K18996 - - 0.00000000000000000000000000000000000000000000000000000000000001443 231.0
HFD2_k127_4216745_0 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000001032 162.0
HFD2_k127_4217687_0 amidohydrolase K21613 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 344.0
HFD2_k127_4217687_1 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000001007 216.0
HFD2_k127_4217687_2 Pterin binding enzyme K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000004076 206.0
HFD2_k127_4217687_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000001868 148.0
HFD2_k127_4217687_4 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000001041 146.0
HFD2_k127_4217687_5 Peptidase M50 - - - 0.00000000000000000000000000000001645 136.0
HFD2_k127_4217702_0 Alanine racemase, N-terminal domain K18425,K19967 - 4.1.2.42,4.1.3.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 325.0
HFD2_k127_4217702_1 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000000000001456 214.0
HFD2_k127_4217702_2 S-acyltransferase activity K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000292 193.0
HFD2_k127_4217702_3 Rdx family K07401 - - 0.000000000000000000000000011 111.0
HFD2_k127_4218888_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 4.024e-263 827.0
HFD2_k127_4227443_0 PFAM 4-hydroxyphenylacetate 3-hydroxylase K00483,K16901 - 1.14.14.8,1.14.14.9 2.019e-201 640.0
HFD2_k127_4227443_1 B12 binding domain K01849 - 5.4.99.2 0.0000000000002346 76.0
HFD2_k127_4242070_0 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000002141 259.0
HFD2_k127_4242070_1 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000003224 231.0
HFD2_k127_4244334_0 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.00000000000000000000000000000001973 134.0
HFD2_k127_4244334_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000002202 128.0
HFD2_k127_4244334_2 peptidase A24 K02278 - 3.4.23.43 0.000000000000000006816 88.0
HFD2_k127_4281171_0 RNA polymerase sigma factor K03088 GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000002154 215.0
HFD2_k127_4281171_1 Putative cyclase - - - 0.0000000000000000000000002839 111.0
HFD2_k127_4281171_2 Sortase family - - - 0.000000000006722 76.0
HFD2_k127_4281171_3 Putative zinc-finger - - - 0.00000000001729 66.0
HFD2_k127_4297708_0 Glycoprotein endo-alpha-1,2-mannosidase-like K15538 GO:0000139,GO:0003674,GO:0003824,GO:0004553,GO:0004559,GO:0004569,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0012505,GO:0015923,GO:0016020,GO:0016787,GO:0016798,GO:0031090,GO:0031984,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044431,GO:0044444,GO:0044446,GO:0044464,GO:0098588,GO:0098791 3.2.1.130 0.000000002231 70.0
HFD2_k127_4310766_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008045 530.0
HFD2_k127_4310766_1 the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms K00958 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 510.0
HFD2_k127_4310766_2 Catalyzes the synthesis of activated sulfate K00390,K00860,K00958,K13811 GO:0000096,GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0004779,GO:0004781,GO:0006082,GO:0006520,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010134,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0019379,GO:0019419,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0070566,GO:0071704,GO:1901564 1.8.4.10,1.8.4.8,2.7.1.25,2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000111 236.0
HFD2_k127_4310766_3 COG3119 Arylsulfatase A and related enzymes - - - 0.0000000000000000000000000000000000005434 149.0
HFD2_k127_4311374_0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000006236 215.0
HFD2_k127_4311374_1 Methyltransferase K10218 - 4.1.3.17 0.000000000000000000000000000000001545 139.0
HFD2_k127_4317851_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000001088 68.0
HFD2_k127_4330947_0 MmgE PrpD family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 329.0
HFD2_k127_4330947_1 MmgE/PrpD family - - - 0.0000000000000000000000000000000000000000000000000000000000000002884 241.0
HFD2_k127_4330947_2 PFAM D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000119 194.0
HFD2_k127_4346686_0 adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 360.0
HFD2_k127_4346686_1 Two component transcriptional regulator, LuxR family - - - 0.000000000000000000000000000000000000000000000000000000000001931 213.0
HFD2_k127_4346686_2 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.000000000000000000000000000000000000000003379 179.0
HFD2_k127_4346686_3 4-Oxalocrotonate Tautomerase - - - 0.0000000000000000000000000003268 121.0
HFD2_k127_4366985_0 F5/8 type C domain - - - 0.0000000000000000000005532 111.0
HFD2_k127_4371229_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000145 231.0
HFD2_k127_4371229_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.6.5.3 0.000000000000000000000004638 107.0
HFD2_k127_4371229_2 Transmembrane secretion effector - - - 0.0000000000000002482 89.0
HFD2_k127_4377825_0 Arylsulfotransferase (ASST) - - - 0.00000000000000000004287 105.0
HFD2_k127_4397466_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 441.0
HFD2_k127_4397466_1 Pyridoxal-phosphate dependent enzyme - - - 0.000000000000000000000000000000000000000000000000009474 187.0
HFD2_k127_4402012_0 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 438.0
HFD2_k127_4423038_0 PFAM Alcohol dehydrogenase zinc-binding domain protein K00153 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.306 0.0000000000000000000000000000000000000000000000000000000000005707 218.0
HFD2_k127_4423038_1 SMART PAS domain containing protein - - - 0.000000000000000000000000000000000002132 151.0
HFD2_k127_4424274_0 Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000001551 196.0
HFD2_k127_4424274_1 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000002057 140.0
HFD2_k127_4424274_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K07003 - - 0.0002903 52.0
HFD2_k127_4447060_0 GDSL-like Lipase/Acylhydrolase family K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 352.0
HFD2_k127_4447060_1 alpha-L-arabinofuranosidase - - - 0.0000000007193 71.0
HFD2_k127_4447060_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000007049 49.0
HFD2_k127_4468989_0 Pfam:HxxPF_rpt - - - 1.611e-310 979.0
HFD2_k127_4468989_1 COG1020 Non-ribosomal peptide synthetase modules and related proteins - - - 2.193e-217 696.0
HFD2_k127_4481511_0 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001263 265.0
HFD2_k127_4481511_1 Transposase - - - 0.00000000000000003204 81.0
HFD2_k127_4489977_0 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004926 466.0
HFD2_k127_4489977_1 Anion-transporting ATPase K01551 - 3.6.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 449.0
HFD2_k127_4489977_2 - - - - 0.00000000000000000000000000000000000003752 144.0
HFD2_k127_4489977_3 - - - - 0.00000000000000000000004513 101.0
HFD2_k127_4489977_4 - - - - 0.0000005438 57.0
HFD2_k127_4498161_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003994 388.0
HFD2_k127_4498161_1 phosphatase - - - 0.00000000000000001834 93.0
HFD2_k127_4498161_2 MOSC domain - - - 0.000000006923 60.0
HFD2_k127_4498161_3 Dolichyl-phosphate-mannose-protein mannosyltransferase K00728 - 2.4.1.109 0.000005732 59.0
HFD2_k127_4498324_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 8.9e-223 709.0
HFD2_k127_4498324_1 Glutamate synthase K00266 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 0.0000002199 52.0
HFD2_k127_4505146_0 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001343 275.0
HFD2_k127_4510478_0 Probable zinc-ribbon domain - - - 0.0000000000000000000000000000000000002722 148.0
HFD2_k127_4510478_1 Succinyl-CoA ligase like flavodoxin domain - - - 0.000000000002701 67.0
HFD2_k127_4510478_2 Formate/nitrite transporter - - - 0.00000001333 56.0
HFD2_k127_4535035_0 FAD binding domain K00480 - 1.14.13.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 388.0
HFD2_k127_4535035_1 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000000000000000005227 222.0
HFD2_k127_4535035_2 Trehalose utilisation K09992 - - 0.0000000000000000000000002009 118.0
HFD2_k127_454689_0 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000000000000000001917 183.0
HFD2_k127_454689_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03117 - - 0.0000000000001419 78.0
HFD2_k127_454689_2 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.00000000004075 66.0
HFD2_k127_454689_3 - - - - 0.00000144 57.0
HFD2_k127_4560290_0 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms K07027 - - 0.0000000006595 70.0
HFD2_k127_4560290_1 Glycosyl transferase 4-like - - - 0.0001268 53.0
HFD2_k127_4582873_0 PFAM von Willebrand factor type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000007682 223.0
HFD2_k127_4582873_1 Carbon monoxide dehydrogenase subunit G (CoxG) - - - 0.000008409 48.0
HFD2_k127_4592977_0 racemase activity, acting on amino acids and derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000002529 238.0
HFD2_k127_4592977_1 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.000000000000000000000000000000000000000000000000000000000009976 220.0
HFD2_k127_4592977_2 Permease family K02824 - - 0.000005802 53.0
HFD2_k127_4609389_0 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000005391 236.0
HFD2_k127_4609389_1 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000002374 187.0
HFD2_k127_4609389_2 sh3 domain protein - - - 0.000000000000000000000000000000000000000000000004086 194.0
HFD2_k127_4609389_3 PFAM N-acetylmuramoyl-L-alanine amidase, family 2 - - - 0.00000000000000000000000000000000000001317 165.0
HFD2_k127_4609389_4 oxidoreductase activity, acting on CH-OH group of donors K03520,K09386 - 1.2.5.3 0.0000002116 58.0
HFD2_k127_4621836_0 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001311 281.0
HFD2_k127_4621836_1 PFAM glycosyl transferase, family 51 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000665 255.0
HFD2_k127_4621836_2 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000003443 95.0
HFD2_k127_4627143_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006403 461.0
HFD2_k127_4627143_1 RNA 2'-O ribose methyltransferase substrate binding K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000002849 239.0
HFD2_k127_4627143_2 YgbB family K01770 - 4.6.1.12 0.0000000000000000000000000000000000000000000000000005836 189.0
HFD2_k127_4627143_3 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.0000000000000000000000000000000000000000000000004793 185.0
HFD2_k127_4627143_4 Integral membrane protein (PIN domain superfamily) - - - 0.0000000000000000000000000000000000000003237 151.0
HFD2_k127_4627276_0 lipopolysaccharide transport K22110 - - 0.0 1093.0
HFD2_k127_4627276_1 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K01838 - 5.4.2.6 0.00000000000000000000000000000000000000000000000007016 188.0
HFD2_k127_4627276_2 Glyoxalase-like domain K05606 - 5.1.99.1 0.00000000000000000000000000000000001383 141.0
HFD2_k127_4627276_3 cytidylyl-transferase K00983,K21749 - 2.7.7.43,2.7.7.92 0.0000000000000000005111 93.0
HFD2_k127_4627276_4 Alkanesulfonate monooxygenase K04091 - 1.14.14.5 0.000000000000001737 77.0
HFD2_k127_4662628_0 Glycosyl transferase family group 2 K07011 - - 0.000000000000000000000000000000000000000000000000000000002556 210.0
HFD2_k127_4662628_1 - - - - 0.000000000000000000000000000000001674 136.0
HFD2_k127_4662628_2 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000001306 118.0
HFD2_k127_4662628_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000008678 82.0
HFD2_k127_4665491_0 Belongs to the ABC transporter superfamily K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003923 379.0
HFD2_k127_4665491_1 Oligopeptide/dipeptide transporter, C-terminal region K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007212 366.0
HFD2_k127_4665491_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 298.0
HFD2_k127_4665491_3 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002385 280.0
HFD2_k127_4680145_0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000001524 230.0
HFD2_k127_4680145_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000001391 101.0
HFD2_k127_4680145_2 Putative cyclase - - - 0.000000000005178 67.0
HFD2_k127_4680145_3 Luciferase-like monooxygenase - - - 0.00000000106 62.0
HFD2_k127_4680145_4 Bacterial SH3 domain - - - 0.00002868 55.0
HFD2_k127_4680145_5 Luciferase-like monooxygenase - - - 0.00004733 48.0
HFD2_k127_4692478_0 - - GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008757,GO:0016278,GO:0016740,GO:0016741,GO:0032259 - 2.423e-267 879.0
HFD2_k127_4692478_1 - - GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008757,GO:0016278,GO:0016740,GO:0016741,GO:0032259 - 0.0000000000000000001686 93.0
HFD2_k127_4704972_0 AAA ATPase domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000844 240.0
HFD2_k127_4706672_0 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 311.0
HFD2_k127_4706672_1 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033,K15581 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002455 275.0
HFD2_k127_4706672_2 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001664 261.0
HFD2_k127_4706672_3 Belongs to the enoyl-CoA hydratase isomerase family K07546,K08299,K15866 - 4.2.1.149,5.3.3.18 0.0000000000000000000000000000000000000000000000000001235 188.0
HFD2_k127_4719883_0 Enoyl-(Acyl carrier protein) reductase K00059,K00068 - 1.1.1.100,1.1.1.140 0.0000000000000000000000000000000000000000000000000000000000000001274 229.0
HFD2_k127_4719883_1 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.000000000000000000000000000000000000000000000000000000004932 214.0
HFD2_k127_4719883_2 PFAM aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.000000000000000000000000000000000000005586 154.0
HFD2_k127_4719883_3 Metallo-beta-lactamase superfamily - - - 0.000000000000000000001502 99.0
HFD2_k127_4741514_0 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009294 317.0
HFD2_k127_4741514_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 296.0
HFD2_k127_4741514_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000003915 256.0
HFD2_k127_4741514_3 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000003661 196.0
HFD2_k127_4741514_4 transcriptional regulator, Rrf2 family - - - 0.000000000000000000000000000000000000000000000005698 175.0
HFD2_k127_4741514_5 PUCC protein - - - 0.0000000000001779 83.0
HFD2_k127_4744851_0 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000001278 201.0
HFD2_k127_4744851_1 Amidohydrolase family - - - 0.000000000000000000000000000000004108 142.0
HFD2_k127_4771336_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 444.0
HFD2_k127_4771336_1 Belongs to the HAD-like hydrolase superfamily K02566 - - 0.000000000000000000000000000000000000000000001862 175.0
HFD2_k127_4771336_2 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.000000000000000000000000000000000000000002801 166.0
HFD2_k127_4771336_3 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000017 50.0
HFD2_k127_4773520_0 transferase activity, transferring glycosyl groups K09118,K13693,K21349 - 2.4.1.266,2.4.1.268 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007907 505.0
HFD2_k127_4773520_1 Glycosyltransferase Family 4 K21369 - 2.4.1.270 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 326.0
HFD2_k127_4773520_2 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0031515,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.219,2.1.1.220 0.000000000000000000000000000000000000000000000000000000000000000000000000002972 263.0
HFD2_k127_4773520_3 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000231 226.0
HFD2_k127_4773520_4 S-adenosylmethionine decarboxylase K01611 - 4.1.1.50 0.0000000000000000000000000000000000000003406 152.0
HFD2_k127_4773520_5 PFAM Phosphoglycerate mutase K22305 - 3.1.3.3 0.0000000000000000000000000000000000000217 150.0
HFD2_k127_4791174_0 E1 component K21416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 355.0
HFD2_k127_4791174_1 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit K00162,K21417 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 302.0
HFD2_k127_4791174_2 PFAM Glycoside hydrolase 15-related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005239 256.0
HFD2_k127_4791174_3 Putative tRNA binding domain K06878 - - 0.000000000000000000000000000000000000001885 148.0
HFD2_k127_4791174_4 Homoserine dehydrogenase, NAD binding domain K18652 - 1.1.1.361 0.000000000003026 75.0
HFD2_k127_4791174_5 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000127 63.0
HFD2_k127_4800337_0 Phage late control gene D protein (GPD) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 344.0
HFD2_k127_4800337_1 Rhs Element Vgr Protein - - - 0.00000000000000000000000000000000000000000000000000000000139 203.0
HFD2_k127_4802005_0 Cobalamin-independent synthase, Catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000001506 197.0
HFD2_k127_4802005_1 Inner membrane component domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000772 160.0
HFD2_k127_4802005_2 Class II Aldolase and Adducin N-terminal domain K10622 - - 0.000000000000000000000000004223 112.0
HFD2_k127_4802298_0 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 451.0
HFD2_k127_4802298_1 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001509 265.0
HFD2_k127_4802592_0 Amidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005792 366.0
HFD2_k127_4802592_1 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000002223 217.0
HFD2_k127_4802592_2 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000827 192.0
HFD2_k127_480546_0 ATPase associated with various cellular K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000471 415.0
HFD2_k127_480546_1 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002245 283.0
HFD2_k127_480546_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000841 257.0
HFD2_k127_480546_3 Transglutaminase/protease-like homologues - - - 0.0000336 55.0
HFD2_k127_4813863_0 acyl-CoA transferases carnitine dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 407.0
HFD2_k127_4813863_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.000000000000000000000000000000000006774 141.0
HFD2_k127_4828672_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007326 581.0
HFD2_k127_4828672_1 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003486 324.0
HFD2_k127_4828672_2 Amino-transferase class IV K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000002395 193.0
HFD2_k127_4828672_3 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 0.0000000000000000000002958 98.0
HFD2_k127_4838124_0 Peptidogalycan biosysnthesis/recognition K09919 - - 0.0000000000000000009624 96.0
HFD2_k127_48529_0 oligosaccharyl transferase activity K07151 - 2.4.99.18 0.0000000000000000000000000000000000000000000000000000007617 222.0
HFD2_k127_48529_1 GGDEF domain containing protein - - - 0.00000000000000000000000005873 125.0
HFD2_k127_48529_2 Psort location CytoplasmicMembrane, score - - - 0.00000000000001432 89.0
HFD2_k127_48529_3 - - - - 0.000000000004174 72.0
HFD2_k127_4855092_0 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07668 GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000006277 178.0
HFD2_k127_4855092_1 metal-dependent membrane protease K07052 - - 0.00000000000000000000000000000953 129.0
HFD2_k127_4855092_2 monoamine oxidase activity K06955 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050664,GO:0051287,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363 - 0.00001215 56.0
HFD2_k127_4864035_0 carbonate dehydratase activity - - - 0.000000000000000000000000000000000000000000001211 174.0
HFD2_k127_4864035_1 PFAM Tetratricopeptide TPR_4 - - - 0.00000000001987 77.0
HFD2_k127_4868463_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 368.0
HFD2_k127_4868463_1 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000002327 170.0
HFD2_k127_4868463_2 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.000000000000000000000000000000005707 138.0
HFD2_k127_4868463_3 Asp Glu Hydantoin racemase family protein - - - 0.000000000000000000000000002462 113.0
HFD2_k127_487770_0 III protein, CoA-transferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005313 454.0
HFD2_k127_487770_1 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000003936 199.0
HFD2_k127_487770_2 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000001953 183.0
HFD2_k127_487770_3 Protein of unknown function (DUF3455) - - - 0.0000009448 51.0
HFD2_k127_4888610_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 6.737e-230 723.0
HFD2_k127_4888610_1 Heat shock 70 kDa protein K04043 - - 0.000000000000000000000000002073 116.0
HFD2_k127_4888610_2 Belongs to the small heat shock protein (HSP20) K13993 - - 0.0000000000001772 76.0
HFD2_k127_4900524_0 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004184 301.0
HFD2_k127_4900524_1 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000003573 237.0
HFD2_k127_4900524_2 Belongs to the LDH2 MDH2 oxidoreductase family K00073,K13574 - 1.1.1.350 0.0000439 46.0
HFD2_k127_4901279_0 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007233 288.0
HFD2_k127_4901962_0 Asparaginase K01424 - 3.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002875 295.0
HFD2_k127_4901962_1 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000001994 211.0
HFD2_k127_4902475_0 Bacterial membrane protein, YfhO - - - 0.000000000000158 82.0
HFD2_k127_4902475_1 Major Facilitator Superfamily - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000006279 61.0
HFD2_k127_4932068_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 387.0
HFD2_k127_4932068_1 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000004282 121.0
HFD2_k127_4932068_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000003555 106.0
HFD2_k127_4932068_3 carboxylic ester hydrolase activity - - - 0.0000000000003655 72.0
HFD2_k127_4936726_0 - K07484 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005435 316.0
HFD2_k127_4936726_1 ABC transporter substrate binding protein K01989 - - 0.0000002118 59.0
HFD2_k127_4957701_0 COGs COG2912 conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000008266 234.0
HFD2_k127_4957701_1 FeS cluster assembly scaffold protein NifU K04488 - - 0.0000000000000000006438 91.0
HFD2_k127_4957701_2 COG3119 Arylsulfatase A and related enzymes - - - 0.0000000000227 73.0
HFD2_k127_4957701_3 - - - - 0.0000000002646 67.0
HFD2_k127_4962580_0 Adenylate and Guanylate cyclase catalytic domain - - - 1.832e-195 621.0
HFD2_k127_4962580_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00001286 48.0
HFD2_k127_4971781_0 Penicillin amidase K01434 - 3.5.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 629.0
HFD2_k127_4971781_1 Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 387.0
HFD2_k127_4971781_10 ABC transporter transmembrane region K06147 - - 0.0000000000000000000000000002375 125.0
HFD2_k127_4971781_11 SnoaL-like domain - - - 0.000000000000000000000001436 106.0
HFD2_k127_4971781_12 Transposase - - - 0.00000000000000000000000308 104.0
HFD2_k127_4971781_13 Transposase - - - 0.000000000004456 70.0
HFD2_k127_4971781_2 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007539 364.0
HFD2_k127_4971781_3 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 354.0
HFD2_k127_4971781_4 Protein of unknown function (DUF1326) - - - 0.00000000000000000000000000000000000000000000000000000000000009469 219.0
HFD2_k127_4971781_5 Nucleotidyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000006036 222.0
HFD2_k127_4971781_6 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000003757 201.0
HFD2_k127_4971781_7 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.0000000000000000000000000000000000000000000000000001551 196.0
HFD2_k127_4971781_8 HxlR-like helix-turn-helix - - - 0.0000000000000000000000000000000000000000003983 168.0
HFD2_k127_4971781_9 N-methylation of lysine residues in flagellin K00599 K18475 - - 0.000000000000000000000000000000002399 144.0
HFD2_k127_4980312_0 MULE transposase domain - - - 3.625e-215 679.0
HFD2_k127_4980312_1 TIR domain - - - 0.0000000000000000000000000000000000000007773 153.0
HFD2_k127_4980312_2 Sulfatase - - - 0.00000000000000003649 82.0
HFD2_k127_4983416_0 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 6.856e-198 622.0
HFD2_k127_4983416_1 Iron-containing alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001272 295.0
HFD2_k127_4983416_2 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000003246 194.0
HFD2_k127_4984004_0 PFAM Luciferase-like, subgroup - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009902 325.0
HFD2_k127_4984004_1 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001708 247.0
HFD2_k127_4984004_2 - - - - 0.000000000000000000000000000000000003633 147.0
HFD2_k127_4984004_3 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000003682 86.0
HFD2_k127_4986747_0 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008743 264.0
HFD2_k127_4986747_1 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000005381 253.0
HFD2_k127_4986747_2 Glyoxalase-like domain K07032 - - 0.000000000000000000000000000000000000003847 151.0
HFD2_k127_4986747_3 S-adenosylhomocysteine deaminase activity K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000062 93.0
HFD2_k127_4999975_0 Iron permease FTR1 family K07243 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006644 350.0
HFD2_k127_4999975_1 iron dependent repressor K03709 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005506,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006355,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009058,GO:0009237,GO:0009712,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0016151,GO:0018958,GO:0019184,GO:0019219,GO:0019222,GO:0019290,GO:0019540,GO:0019748,GO:0030145,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0044550,GO:0045892,GO:0045934,GO:0046870,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0050897,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000004037 169.0
HFD2_k127_4999975_2 cobalamin (vitamin B12) biosynthesis CbiX protein K03795 - 4.99.1.3 0.0000000000000000000000000000704 122.0
HFD2_k127_5001954_0 PFAM 4-hydroxyphenylacetate 3-hydroxylase K00483,K21726 - 1.14.13.166,1.14.13.29,1.14.14.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 507.0
HFD2_k127_5001954_1 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002771 495.0
HFD2_k127_5001954_2 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 390.0
HFD2_k127_5001954_3 TIGRFAM Competence protein ComEA, helix-hairpin-helix K17717 - 3.1.4.4 0.000000000000000000000000000000000000000000000000000000000000000624 234.0
HFD2_k127_5001954_4 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000006001 209.0
HFD2_k127_5001954_5 ABC transporter transmembrane region K06147 - - 0.00000000000000000000000000002693 119.0
HFD2_k127_5002757_0 Prolyl oligopeptidase family K06889 - - 0.000000000000000000000000000000000000000000001088 179.0
HFD2_k127_5002757_1 PFAM major facilitator superfamily MFS_1 - - - 0.000000003589 66.0
HFD2_k127_5007546_0 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000002545 212.0
HFD2_k127_5007546_1 PFAM Haloacid dehalogenase domain protein hydrolase K07025 - - 0.00000000000000000000000000001985 127.0
HFD2_k127_5009112_0 Forkhead associated domain - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944 - 0.000000004964 69.0
HFD2_k127_5011802_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 5.916e-196 642.0
HFD2_k127_5011802_1 acetylesterase activity K01046 - 3.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000001588 263.0
HFD2_k127_5011802_2 Amidohydrolase K03392 - 4.1.1.45 0.0000000000000000000000000000000000000000000000000000000003155 221.0
HFD2_k127_501545_0 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) K03740 - - 0.0000000000000000000000000000000000000000000000000000000000000000122 243.0
HFD2_k127_501545_1 Bacterial SH3 domain - - - 0.0003928 52.0
HFD2_k127_5016817_0 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004216 320.0
HFD2_k127_5016817_1 CO dehydrogenase flavoprotein domain protein K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 293.0
HFD2_k127_5016817_2 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000002447 126.0
HFD2_k127_5017880_0 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 360.0
HFD2_k127_5017880_1 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002032 256.0
HFD2_k127_5017880_2 - - - - 0.000000000000000009585 88.0
HFD2_k127_5017880_3 depolymerase - - - 0.0000000000003632 80.0
HFD2_k127_5017880_4 - K16937 - 1.8.5.2 0.00000006243 61.0
HFD2_k127_5025482_0 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 491.0
HFD2_k127_5025482_1 - - - - 0.0000000000000000000000000000000000000000001322 166.0
HFD2_k127_5039444_0 PFAM amine oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004853 466.0
HFD2_k127_5039444_1 Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001656 261.0
HFD2_k127_5039444_2 Mannose-6-phosphate isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000001474 215.0
HFD2_k127_5039444_3 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000006134 227.0
HFD2_k127_5039444_4 cheY-homologous receiver domain - - - 0.000000000000000000000000000008855 124.0
HFD2_k127_5051537_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000374 452.0
HFD2_k127_5051537_1 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 452.0
HFD2_k127_5051537_2 Belongs to the N(4) N(6)-methyltransferase family K00571,K00590 - 2.1.1.113,2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007371 278.0
HFD2_k127_5051537_3 PFAM NAD-dependent epimerase dehydratase K01784,K10011,K12449 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006040,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016741,GO:0016742,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0022607,GO:0033319,GO:0033320,GO:0034214,GO:0034641,GO:0034654,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046349,GO:0046483,GO:0046677,GO:0048037,GO:0048040,GO:0050662,GO:0050896,GO:0051259,GO:0051287,GO:0055086,GO:0055114,GO:0065003,GO:0070403,GO:0071704,GO:0071840,GO:0097159,GO:0099618,GO:0099619,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:2001313,GO:2001315 1.1.1.305,2.1.2.13,5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009784 278.0
HFD2_k127_5051537_5 NAD-dependent epimerase dehydratase K01784,K17947 - 5.1.3.2,5.1.3.25 0.00000000000000000000000000000000000746 149.0
HFD2_k127_5051537_6 Glycosyltransferase like family 2 - - - 0.00008395 53.0
HFD2_k127_5052256_0 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 386.0
HFD2_k127_5052256_1 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000001872 123.0
HFD2_k127_505448_0 PFAM carboxyl transferase K01969,K15052 - 2.1.3.15,6.4.1.3,6.4.1.4 1.925e-250 778.0
HFD2_k127_505448_1 Biotin carboxylase C-terminal domain K01965,K01968,K13777 - 6.4.1.3,6.4.1.4,6.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 591.0
HFD2_k127_505448_2 HMGL-like K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003529 335.0
HFD2_k127_505448_3 - - - - 0.0000000000000000005438 91.0
HFD2_k127_505448_4 Peptidase M50 K16922 - - 0.0002229 48.0
HFD2_k127_505448_5 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.0004732 49.0
HFD2_k127_5057081_0 peptidase dimerisation domain protein K01436 - - 0.00000000000000000000000000000000000000000000000000000000000000004226 231.0
HFD2_k127_5057081_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K00087 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000509 208.0
HFD2_k127_5065698_0 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000007109 91.0
HFD2_k127_5065698_1 cytochrome P450 - - - 0.000000000000009071 79.0
HFD2_k127_5065698_2 - - - - 0.00000000000001018 81.0
HFD2_k127_5069548_0 PFAM Sodium hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 317.0
HFD2_k127_5089659_0 PFAM ATPase associated with various cellular activities, AAA_3 K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003617 364.0
HFD2_k127_5089659_1 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 359.0
HFD2_k127_5089659_2 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001909 254.0
HFD2_k127_5089659_3 PFAM von Willebrand factor type A - - - 0.00000000000002274 81.0
HFD2_k127_5092077_0 FeS assembly protein SufB K07033,K09014 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - 2.16e-231 725.0
HFD2_k127_5092077_1 ATPases associated with a variety of cellular activities K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 321.0
HFD2_k127_5092077_2 Uncharacterized protein family (UPF0051) K09015 - - 0.0000000000000000000000000000000000000002573 158.0
HFD2_k127_5092077_3 Transcriptional regulator - - - 0.00000000000000000000000000000000000001625 150.0
HFD2_k127_5092077_4 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000003954 118.0
HFD2_k127_5092077_5 Belongs to the 'phage' integrase family - - - 0.0001812 47.0
HFD2_k127_5093200_0 Molydopterin dinucleotide binding domain K08352 - 1.8.5.5 5.058e-243 769.0
HFD2_k127_5093200_1 Periplasmic binding protein domain K01999 - - 0.0000000000000000000000000000000000000000000000000000005411 207.0
HFD2_k127_5093200_2 phosphoenolpyruvate synthase K01007 - 2.7.9.2 0.0000000000000000000000000000000002097 141.0
HFD2_k127_5093200_3 Major facilitator Superfamily - - - 0.0004185 47.0
HFD2_k127_5094584_0 prohibitin homologues K07192 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 554.0
HFD2_k127_5094584_1 sequence-specific DNA binding K03427 - 2.1.1.72 0.00000000000000000000000000000000000003105 151.0
HFD2_k127_5094584_2 cellular response to DNA damage stimulus - GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0033554,GO:0044464,GO:0050896,GO:0051716,GO:0071944 - 0.000000000000000000000000004918 120.0
HFD2_k127_5095677_0 Glycyl-tRNA synthetase alpha subunit K14164 - 6.1.1.14 1.325e-231 746.0
HFD2_k127_5095677_1 Phenazine biosynthesis-like protein K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000892 247.0
HFD2_k127_5095677_2 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000006955 238.0
HFD2_k127_5095677_3 GYD domain - - - 0.00000000000000000000000000000000000002057 147.0
HFD2_k127_5095677_4 Belongs to the ParB family K03497 - - 0.000000000000000007118 87.0
HFD2_k127_5095677_5 - - - - 0.00000000000000001167 90.0
HFD2_k127_5101028_0 Heat shock 70 kDa protein K04043 - - 1.599e-231 724.0
HFD2_k127_5101028_1 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000005176 144.0
HFD2_k127_5101028_2 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K00657 - 2.3.1.57 0.00000003828 60.0
HFD2_k127_5107592_0 HTH-like domain K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 301.0
HFD2_k127_5107592_1 Transposase - - - 0.000000000000000000000005787 106.0
HFD2_k127_5107592_2 transposition K07497 - - 0.000003356 49.0
HFD2_k127_5115612_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.379e-265 837.0
HFD2_k127_5115612_1 Xaa-Pro dipeptidase K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009239 327.0
HFD2_k127_5115612_2 DNA recombination-mediator protein A K03168,K04096 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 299.0
HFD2_k127_5120948_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003108 265.0
HFD2_k127_5120948_1 Alpha-tubulin suppressor and related RCC1 domain-containing proteins - - - 0.0000000000000000000000000000000000000000000000000000003099 209.0
HFD2_k127_5120948_2 Conserved repeat domain - - - 0.0000000000009986 80.0
HFD2_k127_5120948_3 Nitroreductase family - - - 0.00000000001335 64.0
HFD2_k127_5124195_0 KR domain K00065 - 1.1.1.127 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007291 321.0
HFD2_k127_5124195_1 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000000000000000000001721 182.0
HFD2_k127_5136217_0 VanW like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004246 308.0
HFD2_k127_5136217_1 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000005238 248.0
HFD2_k127_5136217_2 dUTPase K01520 - 3.6.1.23 0.000000000000000000000000000000000000006229 151.0
HFD2_k127_5136217_3 Maf-like protein K06287 - - 0.00000000000000000000000000000001645 136.0
HFD2_k127_5140353_0 alginic acid biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 611.0
HFD2_k127_5140353_1 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000009832 158.0
HFD2_k127_5152831_0 PFAM cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008196 453.0
HFD2_k127_5152831_1 Hydantoin racemase K16841 - 5.1.99.3 0.000000000000000104 91.0
HFD2_k127_5152831_2 Uncharacterized conserved protein (DUF2277) - - - 0.000000000008341 68.0
HFD2_k127_5152831_3 Major facilitator Superfamily K08178 - - 0.0000006994 61.0
HFD2_k127_5156694_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 2.509e-206 662.0
HFD2_k127_5156694_1 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000007173 216.0
HFD2_k127_5156694_2 catechol 1,2-dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000003301 206.0
HFD2_k127_5156694_3 protein conserved in cyanobacteria - - - 0.0000000000000000000000000000000000005081 143.0
HFD2_k127_5158134_0 Sodium/calcium exchanger protein K07300 - - 0.00000000000000000000000000000000000000000000000000000000000000000002145 245.0
HFD2_k127_5160801_0 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003881 544.0
HFD2_k127_5160801_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 291.0
HFD2_k127_5160801_2 - - - - 0.0000000000000000000000000000000000000000000000000000004382 201.0
HFD2_k127_5160801_3 Serine aminopeptidase, S33 K01253,K08253 - 2.7.10.2,3.3.2.9 0.00000000000000000000000000000000000007517 146.0
HFD2_k127_5172335_0 PFAM Bacterial domain of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004178 251.0
HFD2_k127_5172335_1 Circularly permuted ATP-grasp type 2 - - - 0.0000000000007599 68.0
HFD2_k127_5172335_2 Transglutaminase/protease-like homologues - - - 0.000000000007344 71.0
HFD2_k127_5185515_0 Luciferase-like monooxygenase K04091,K17228 - 1.14.14.35,1.14.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000002327 263.0
HFD2_k127_5185515_1 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000009972 257.0
HFD2_k127_5189712_0 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005652 511.0
HFD2_k127_5189712_1 Ketopantoate reductase PanE/ApbA C terminal - - - 0.000000000000000000000000000000000000000000000000000002276 199.0
HFD2_k127_5189712_2 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000001473 190.0
HFD2_k127_5195366_0 alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 507.0
HFD2_k127_5195366_1 Sigma-70 region 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000005829 238.0
HFD2_k127_5195366_2 Spondin_N - - - 0.000000000000000000002629 104.0
HFD2_k127_5195366_3 Putative zinc-finger - - - 0.000000000001037 72.0
HFD2_k127_5195366_4 Putative zinc-finger - - - 0.00000000006575 68.0
HFD2_k127_5195366_5 Putative cyclase - - - 0.000002684 51.0
HFD2_k127_5201629_0 Family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000006148 237.0
HFD2_k127_5201629_1 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000000000002231 179.0
HFD2_k127_520924_0 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003147 383.0
HFD2_k127_520924_1 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 305.0
HFD2_k127_520924_2 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000003067 175.0
HFD2_k127_520924_3 Protein of unknown function (DUF2889) K07053 - 3.1.3.97 0.00000000000000000000000000000000002843 143.0
HFD2_k127_520924_4 CoA-transferase family III - - - 0.0000000000000000000005891 98.0
HFD2_k127_5210121_0 Protealysin propeptide K01400 - 3.4.24.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 407.0
HFD2_k127_5210121_1 DDE superfamily endonuclease - - - 0.0000000000000000000000000000001249 131.0
HFD2_k127_5210121_2 Homeodomain-like domain - - - 0.000000000000000001051 93.0
HFD2_k127_5210121_3 - - - - 0.000000000001367 74.0
HFD2_k127_5249043_0 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004461 463.0
HFD2_k127_5249043_1 methylamine metabolic process K15977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004258 313.0
HFD2_k127_5249043_2 - - - - 0.0000000000000000000000000000000000000000000004249 176.0
HFD2_k127_5249043_3 - - - - 0.00000000000000000000000000000006544 130.0
HFD2_k127_5249043_4 polysaccharide deacetylase - - - 0.00001355 48.0
HFD2_k127_5249043_5 Polysaccharide deacetylase - - - 0.0001425 47.0
HFD2_k127_5252903_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008494 350.0
HFD2_k127_5252903_1 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 323.0
HFD2_k127_5252903_2 Belongs to the enoyl-CoA hydratase isomerase family. MenB subfamily K01661 - 4.1.3.36 0.000000000000003574 80.0
HFD2_k127_5256769_0 PFAM Transposase domain (DUF772) K07487 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 564.0
HFD2_k127_5288928_0 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 356.0
HFD2_k127_5288928_1 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002807 308.0
HFD2_k127_5291123_0 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000001144 229.0
HFD2_k127_5291123_1 Terminase-like family - - - 0.000000000000000000003207 100.0
HFD2_k127_5295569_0 Non-ribosomal peptide synthetase modules and related proteins - - - 0.0 1233.0
HFD2_k127_5295569_1 TIGRFAM amino acid adenylation domain K16132 - - 0.000000000000000000000000000000000000000000002794 169.0
HFD2_k127_5307678_0 Belongs to the peptidase S16 family K07177 - - 0.000000000000000000000000000000000000000000000000001326 196.0
HFD2_k127_5307678_1 PFAM Asp Glu K16841 - 5.1.99.3 0.00000000000000000000000000000000000000000101 166.0
HFD2_k127_5307678_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000002421 124.0
HFD2_k127_5307678_3 EamA-like transporter family - - - 0.0000000000000002341 91.0
HFD2_k127_5307678_4 NYN domain - - - 0.0000000008904 71.0
HFD2_k127_5307678_5 Peptidase family M50 - - - 0.0003341 44.0
HFD2_k127_5313499_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000488 357.0
HFD2_k127_5313499_1 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000001741 204.0
HFD2_k127_5313499_2 Prokaryotic dksA traR C4-type zinc finger - - - 0.0000001172 58.0
HFD2_k127_5313513_0 ABC transporter (Permease) K10118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 379.0
HFD2_k127_5313513_1 Extracellular solute-binding protein K02027,K10117 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007268 274.0
HFD2_k127_5323470_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 5.457e-198 636.0
HFD2_k127_5323470_1 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007311 385.0
HFD2_k127_5323470_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 351.0
HFD2_k127_5323470_3 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008099 269.0
HFD2_k127_5323470_4 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000001133 259.0
HFD2_k127_5323470_5 Belongs to the ribF family K07011,K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000002852 256.0
HFD2_k127_5323470_6 zinc metalloprotease K04771,K11749,K16922 GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016021,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0040007,GO:0043170,GO:0043856,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045152,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:0140110,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000007452 250.0
HFD2_k127_5323470_7 Protein of unknown function (DUF448) K07742 - - 0.00000000000000000000002285 102.0
HFD2_k127_5323470_8 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000001641 101.0
HFD2_k127_5339143_0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 321.0
HFD2_k127_5339143_1 - - - - 0.0000000000000000000000004194 115.0
HFD2_k127_5339143_2 Protein of unknown function (DUF2933) - - - 0.000000000000001054 81.0
HFD2_k127_5339143_3 Domain of unknown function (DUF4142) - - - 0.00000000000005675 74.0
HFD2_k127_5339143_4 membrane protein (DUF2078) K08982 - - 0.0000000000008754 74.0
HFD2_k127_5339143_5 - - - - 0.0000000001713 73.0
HFD2_k127_5349741_0 - - - - 0.00002651 54.0
HFD2_k127_5353507_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 379.0
HFD2_k127_5353507_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00001219 58.0
HFD2_k127_5355510_0 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 404.0
HFD2_k127_5355510_1 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 357.0
HFD2_k127_5355510_2 Belongs to the glycosyl hydrolase 31 family K01811 - 3.2.1.177 0.00000000000000000000000000000000000000000000000000000000000000007613 235.0
HFD2_k127_5355510_3 Transposase - - - 0.00000005879 59.0
HFD2_k127_5366138_0 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 429.0
HFD2_k127_5366138_1 response regulator K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005633 258.0
HFD2_k127_5366138_2 Amidohydrolase K03392 - 4.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000001861 248.0
HFD2_k127_5366138_3 histidine kinase A domain protein K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000004666 232.0
HFD2_k127_5366138_4 NYN domain - - - 0.0000000000000000000000001856 117.0
HFD2_k127_5366138_5 His Kinase A (phosphoacceptor) domain - - - 0.0003111 52.0
HFD2_k127_5367558_0 3'(2'),5'-bisphosphate nucleotidase K01082 - 3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000009118 248.0
HFD2_k127_5367558_1 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000000000003283 129.0
HFD2_k127_5367876_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004271 318.0
HFD2_k127_5367876_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000001534 191.0
HFD2_k127_537277_0 PFAM Tetratricopeptide TPR_4 - - - 4.236e-224 708.0
HFD2_k127_537277_1 NAD(P)-binding Rossmann-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 503.0
HFD2_k127_5393272_0 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 489.0
HFD2_k127_5393272_1 PFAM MmgE PrpD family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002404 282.0
HFD2_k127_5393272_2 PFAM Transposase IS116 IS110 IS902 family - - - 0.00000000000000001755 83.0
HFD2_k127_5393272_3 helix_turn_helix isocitrate lyase regulation - - - 0.00000002369 57.0
HFD2_k127_540566_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002969 599.0
HFD2_k127_540566_1 LysM domain M23 M37 peptidase domain protein - - - 0.0000000000000000000000000000000000000000001945 173.0
HFD2_k127_540566_2 3D domain protein - - - 0.00000000000001382 75.0
HFD2_k127_5426520_0 PFAM ABC transporter related K01990,K09691,K09693 - 3.6.3.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003086 303.0
HFD2_k127_5426520_1 COG1682 ABC-type polysaccharide polyol phosphate export systems, permease component K09690 - - 0.0000000000000000000000000000000000000000000000000000000000418 217.0
HFD2_k127_5426520_2 Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC - - - 0.000000000000000000000000000001786 137.0
HFD2_k127_5426520_3 PFAM Glycosyl transferase, group 1 K19424 - - 0.000000000000008445 81.0
HFD2_k127_5426520_4 Glycosyltransferase like family 2 K07011,K20444 - - 0.000000000823 71.0
HFD2_k127_5426520_5 GDP-mannose 4,6 dehydratase K01784 - 5.1.3.2 0.00004342 47.0
HFD2_k127_5430425_0 ABC transporter transmembrane region K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005755 329.0
HFD2_k127_5430425_1 COGs COG1253 Hemolysins and related protein containing CBS domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000034 286.0
HFD2_k127_5430425_2 Oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001914 262.0
HFD2_k127_5430425_3 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K18687 - 6.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000289 259.0
HFD2_k127_5430425_4 Succinyl-CoA ligase like flavodoxin domain - - - 0.0000000000000000000000008588 111.0
HFD2_k127_5430425_5 membrane - - - 0.000000003814 70.0
HFD2_k127_544982_0 Belongs to the sigma-70 factor family. ECF subfamily - - - 2.174e-211 664.0
HFD2_k127_544982_1 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 476.0
HFD2_k127_544982_2 Belongs to the peptidase S8 family K13274,K14645 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 380.0
HFD2_k127_544982_3 YCII-related domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000102 239.0
HFD2_k127_544982_4 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.0000000000000000000000000000000000000000000000000000000000000006025 225.0
HFD2_k127_544982_5 3-demethylubiquinone-9 3-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000001898 201.0
HFD2_k127_544982_6 protein conserved in bacteria K04750 - - 0.0000000000000000000000000000000000000000000000000001561 188.0
HFD2_k127_544982_7 DoxX-like family - - - 0.0000000000000000000000000000000000001137 145.0
HFD2_k127_544982_8 - - - - 0.00004708 49.0
HFD2_k127_5454516_0 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 526.0
HFD2_k127_5454516_1 Belongs to the mandelate racemase muconate lactonizing enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007411 271.0
HFD2_k127_5455194_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007913 451.0
HFD2_k127_5455194_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.000000000000000000000000000005215 124.0
HFD2_k127_5455194_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000002138 99.0
HFD2_k127_5462158_0 AAA domain (dynein-related subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 376.0
HFD2_k127_5462158_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 338.0
HFD2_k127_5462158_2 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008491 288.0
HFD2_k127_5462158_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001118 299.0
HFD2_k127_5462158_4 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002817 254.0
HFD2_k127_5462158_5 - - - - 0.000000000000000000000005857 104.0
HFD2_k127_5462158_6 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000003064 92.0
HFD2_k127_5462158_7 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000116 69.0
HFD2_k127_5493570_0 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 462.0
HFD2_k127_5493570_1 Protease prsW family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 295.0
HFD2_k127_5493570_2 OsmC-like protein - - - 0.000004785 48.0
HFD2_k127_5497808_0 N-methylhydantoinase A acetone carboxylase, beta subunit K01469,K01473 - 3.5.2.14,3.5.2.9 1.344e-220 705.0
HFD2_k127_5497808_1 N-methylhydantoinase B acetone carboxylase alpha subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004623 618.0
HFD2_k127_5497808_2 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000005467 207.0
HFD2_k127_5497808_3 2-keto-3-deoxy-L-rhamnonate aldolase activity K02510,K12660 - 4.1.2.52,4.1.2.53 0.00000000000000000000000000000000000000203 151.0
HFD2_k127_5497808_4 Alpha/beta hydrolase family - - - 0.000000000000000000000009317 108.0
HFD2_k127_5505388_0 Resolvase, N terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005304 274.0
HFD2_k127_5505388_1 PFAM Tetratricopeptide repeat - - - 0.00001187 54.0
HFD2_k127_5525091_0 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 5.949e-213 686.0
HFD2_k127_5525091_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 528.0
HFD2_k127_5525091_2 RibD C-terminal domain K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 325.0
HFD2_k127_5525091_3 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000001065 214.0
HFD2_k127_5525091_4 TIGRFAM riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000001169 215.0
HFD2_k127_5525091_5 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000005054 97.0
HFD2_k127_5525091_6 MmgE/PrpD family - - - 0.0000003236 58.0
HFD2_k127_5532724_0 PFAM glycoside hydrolase family 39 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 385.0
HFD2_k127_5532724_1 CBS domain containing protein K03699 - - 0.00000000000000001359 85.0
HFD2_k127_5532724_2 protein conserved in bacteria - - - 0.0000000002494 69.0
HFD2_k127_553541_0 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00366,K00392 - 1.7.7.1,1.8.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000835 604.0
HFD2_k127_553541_1 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 405.0
HFD2_k127_553541_10 - - - - 0.0000000000000000000000000002708 119.0
HFD2_k127_553541_12 pyridoxamine 5-phosphate - - - 0.00000000000000004891 85.0
HFD2_k127_553541_2 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 383.0
HFD2_k127_553541_3 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 338.0
HFD2_k127_553541_4 Acyl CoA acetate 3-ketoacid CoA transferase beta subunit K01032 - 2.8.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000685 261.0
HFD2_k127_553541_5 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01034 - 2.8.3.8,2.8.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000002422 259.0
HFD2_k127_553541_6 Catalyzes the synthesis of activated sulfate K00390,K00860,K00958,K13811 GO:0000096,GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0004779,GO:0004781,GO:0006082,GO:0006520,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010134,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0019379,GO:0019419,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0070566,GO:0071704,GO:1901564 1.8.4.10,1.8.4.8,2.7.1.25,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000002331 226.0
HFD2_k127_553541_7 ABC transporter K01990 - - 0.000000000000000000000000000000006869 129.0
HFD2_k127_553541_8 integral membrane protein - - - 0.00000000000000000000000000000009528 134.0
HFD2_k127_553541_9 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000003003 137.0
HFD2_k127_5539793_0 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 512.0
HFD2_k127_5539793_1 NHL repeat - - - 0.000729 44.0
HFD2_k127_554779_0 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 379.0
HFD2_k127_554779_1 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000002205 243.0
HFD2_k127_554779_2 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0005488,GO:0005507,GO:0005575,GO:0005576,GO:0005615,GO:0005623,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008270,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0030288,GO:0030313,GO:0031975,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044421,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 0.0000000000000000000000000000000000000000002492 169.0
HFD2_k127_554779_3 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000006805 82.0
HFD2_k127_5550898_0 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003006 276.0
HFD2_k127_5550898_1 Alcohol dehydrogenase GroES-like domain K00153 - 1.1.1.306 0.00000000000000000000000000000000000000000000000000000000000001227 220.0
HFD2_k127_5555406_0 Amidohydrolase family K01464 - 3.5.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 326.0
HFD2_k127_5555406_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000004379 182.0
HFD2_k127_5555406_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000002187 169.0
HFD2_k127_5555406_3 Luciferase-like monooxygenase - - - 0.0000000000000000000000000005043 119.0
HFD2_k127_5555406_4 Extracellular solute-binding protein, family 5 K02035 - - 0.00000000000000000000000006179 119.0
HFD2_k127_5555406_5 Peptidase family S51 - - - 0.000000000105 71.0
HFD2_k127_5573776_0 Sulfatase - - - 0.000000000000000000000001121 115.0
HFD2_k127_5573776_1 Belongs to the 'phage' integrase family - - - 0.000000000000000000000008907 109.0
HFD2_k127_5573776_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000009628 84.0
HFD2_k127_5583056_0 Branched-chain amino acid transport system / permease component K01997,K01998 - - 0.00000000000000000000000000000000000000000000000000000000005323 217.0
HFD2_k127_5583056_1 Belongs to the binding-protein-dependent transport system permease family K01997,K01998 - - 0.000000000000000000001793 104.0
HFD2_k127_5583056_2 L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.000001771 49.0
HFD2_k127_5590337_0 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 316.0
HFD2_k127_5590337_1 Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively K04101 - 1.13.11.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001417 276.0
HFD2_k127_5590337_2 Glycosyl transferases group 1 K13057 - 2.4.1.245 0.000000000000000000000000000000000000000000000000000000000000000003384 245.0
HFD2_k127_5590337_3 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.0000000000000000000000000000000000000000000000001532 186.0
HFD2_k127_5595402_0 R3H domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 592.0
HFD2_k127_5595402_1 TrkA-C domain K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002965 250.0
HFD2_k127_5595402_2 HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000003785 212.0
HFD2_k127_5595402_3 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000001984 201.0
HFD2_k127_5595402_4 TrkA-N domain K03499 - - 0.000000000000000000000000000000000000000000002954 168.0
HFD2_k127_5595402_5 Mandelate Racemase Muconate Lactonizing K01781,K20023,K20549 - 4.2.1.156,4.2.1.42,5.1.2.2,5.5.1.25 0.0000000000000000000000000000000003425 139.0
HFD2_k127_5595402_6 PFAM NIPSNAP family containing protein - - - 0.0000000000000000000000000000000003531 134.0
HFD2_k127_5595402_7 Universal stress protein family - - - 0.00000000000000000000000000000001484 131.0
HFD2_k127_5595402_9 Protein of unknown function (DUF1232) - - - 0.00000000000324 71.0
HFD2_k127_5600341_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 501.0
HFD2_k127_5600341_1 PFAM IstB domain protein ATP-binding protein K02315 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004686 316.0
HFD2_k127_5600341_2 TIGRFAM primosome, DnaD subunit - - - 0.00000000000000000000000000000000000000000001593 172.0
HFD2_k127_564023_0 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 307.0
HFD2_k127_564023_1 Belongs to the carbohydrate kinase PfkB family K00874 - 2.7.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000008668 254.0
HFD2_k127_564023_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000004871 241.0
HFD2_k127_564023_3 phosphatidylinositol metabolic process - - - 0.0001992 49.0
HFD2_k127_5644002_0 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000003237 161.0
HFD2_k127_5644002_1 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000009336 158.0
HFD2_k127_5654376_0 alpha-L-arabinofuranosidase - - - 0.000000000000000002051 98.0
HFD2_k127_5654376_1 Fumarate reductase flavoprotein C-term K00278 - 1.4.3.16 0.0007647 44.0
HFD2_k127_56578_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 481.0
HFD2_k127_56578_1 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000004076 223.0
HFD2_k127_56578_2 PFAM blue (type 1) copper domain protein - - - 0.0006535 49.0
HFD2_k127_566557_0 N-terminal domain of (some) glycogen debranching enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003029 613.0
HFD2_k127_566557_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000003873 254.0
HFD2_k127_566557_2 Glycosyltransferase family 28 N-terminal domain K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000009906 256.0
HFD2_k127_566557_3 Putative NAD(P)-binding K02304 - 1.3.1.76,4.99.1.4 0.000000000000000000000000000000000000000003177 162.0
HFD2_k127_566557_4 Helix-turn-helix domain - - - 0.0000000000000000000000001148 116.0
HFD2_k127_566557_5 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0001073 46.0
HFD2_k127_5676123_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 346.0
HFD2_k127_5676123_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000000001182 185.0
HFD2_k127_5681880_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 541.0
HFD2_k127_5681880_1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000933 301.0
HFD2_k127_5681880_2 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000004425 161.0
HFD2_k127_5682960_0 Amidohydrolase K03392 - 4.1.1.45 0.00000000000000000000000000000000000000000000000000002597 198.0
HFD2_k127_5682960_1 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000001018 192.0
HFD2_k127_5684770_0 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K00167 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 430.0
HFD2_k127_5684770_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007115 400.0
HFD2_k127_5684770_10 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000001136 194.0
HFD2_k127_5684770_11 Bacterial transferase hexapeptide (six repeats) K02617 - - 0.0000000000000000000000000000000000000000000007175 173.0
HFD2_k127_5684770_12 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.0000000000000000000000000000000000006327 145.0
HFD2_k127_5684770_13 Xylose isomerase-like TIM barrel K22233 - - 0.00000000000000000000000000008717 124.0
HFD2_k127_5684770_14 Polynucleotide kinase 3 phosphatase - - - 0.000000000000000000004304 102.0
HFD2_k127_5684770_15 Catalyzes the synthesis of activated sulfate K00860,K07028 - 2.7.1.25 0.000000000000001269 83.0
HFD2_k127_5684770_16 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - 0.000000000000005467 81.0
HFD2_k127_5684770_17 - - - - 0.00000003483 63.0
HFD2_k127_5684770_18 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0000003499 57.0
HFD2_k127_5684770_2 e3 binding domain K00627,K09699 - 2.3.1.12,2.3.1.168 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004912 406.0
HFD2_k127_5684770_3 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 326.0
HFD2_k127_5684770_4 Peptidase family M28 K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 323.0
HFD2_k127_5684770_5 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 317.0
HFD2_k127_5684770_6 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 303.0
HFD2_k127_5684770_7 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002701 278.0
HFD2_k127_5684770_8 GTPase activity K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007023 257.0
HFD2_k127_5684770_9 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000000000000000004501 207.0
HFD2_k127_5685240_0 Binding-protein-dependent transport system inner membrane component K05773 - - 0.000000000000000000000000000000000000000000000000000000000000000000001013 244.0
HFD2_k127_5685240_1 Belongs to the HesB IscA family K13628 - - 0.000000000000000000000000000000000006099 139.0
HFD2_k127_5685240_2 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000009346 148.0
HFD2_k127_5685240_3 ECF sigma factor K03088 - - 0.000000000000000000000000000000001092 143.0
HFD2_k127_5685240_4 PFAM PKD domain containing protein - - - 0.0000000000000000000000000003749 127.0
HFD2_k127_5685240_5 An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK. ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut extracytoplasmically (site-1 protease, S1P), then within the membrane itself (site-2 protease, S2P, Rip1), while cytoplasmic proteases finish degrading the regulatory protein, liberating the sigma factor - - - 0.0000000000000002654 90.0
HFD2_k127_5697081_0 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007165 315.0
HFD2_k127_5706157_0 Belongs to the peptidase M50B family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005787 289.0
HFD2_k127_5706157_1 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000000000000000000000000000000001121 219.0
HFD2_k127_5709298_0 PFAM glycosyl transferase, family 28 K05841 - 2.4.1.173 0.000000000000000000000000000000000000000000000000000001987 205.0
HFD2_k127_5709298_1 cytochrome P450 - - - 0.000000000000000000000000004673 119.0
HFD2_k127_5709298_2 cytochrome p450 - - - 0.000000000000000000000002271 109.0
HFD2_k127_5727350_0 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006311 382.0
HFD2_k127_5727350_1 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004503 304.0
HFD2_k127_5727350_2 AhpC/TSA family - - - 0.0000000000000000000000000000000000000000000000000000000000001705 225.0
HFD2_k127_5727350_3 Adenylate K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000002924 187.0
HFD2_k127_5727350_4 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000007969 106.0
HFD2_k127_5727350_5 Acetyltransferase (GNAT) domain - - - 0.00000005794 53.0
HFD2_k127_5727350_6 Carbon-nitrogen hydrolase - - - 0.000001373 50.0
HFD2_k127_5727350_7 Carbon-nitrogen hydrolase - - - 0.000539 43.0
HFD2_k127_5728245_0 COG1062 Zn-dependent alcohol dehydrogenases, class III K00001,K00121 - 1.1.1.1,1.1.1.284 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 467.0
HFD2_k127_5728245_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000007573 226.0
HFD2_k127_5728245_2 Thioredoxin-like - - - 0.0000000000000000000002082 106.0
HFD2_k127_5728245_3 SMART AAA ATPase K06923 - - 0.0000000004579 68.0
HFD2_k127_5729573_0 Alcohol dehydrogenase zinc-binding domain protein K13953,K18382 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006933 339.0
HFD2_k127_5729573_1 Belongs to the UPF0310 family - - - 0.00000000000000000000000000000000000000000000000002533 183.0
HFD2_k127_5729573_2 PFAM Membrane protein of K08972 - - 0.0000000000000000000000008149 108.0
HFD2_k127_5729573_3 Acyl-protein synthetase, LuxE - - - 0.0000000000002204 83.0
HFD2_k127_5731740_0 signal sequence binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000001521 237.0
HFD2_k127_5731740_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000005812 248.0
HFD2_k127_5731740_2 Two component transcriptional regulator, winged helix family K07667,K07668 - - 0.00000000000000000000000000000000000000000000000000000000001708 215.0
HFD2_k127_5734975_0 Protein of unknown function DUF72 - - - 0.00000000000000009095 84.0
HFD2_k127_5734975_1 Endonuclease/Exonuclease/phosphatase family - - - 0.00000003819 63.0
HFD2_k127_5747903_0 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 334.0
HFD2_k127_5747903_1 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006948 287.0
HFD2_k127_5747903_2 Extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000003405 123.0
HFD2_k127_5750281_0 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000001345 214.0
HFD2_k127_5750281_1 Ferric uptake regulator family K22297 - - 0.0000000000000000000000000000000000000000000000000000002713 197.0
HFD2_k127_5761409_0 ABC-type Fe3 transport system permease component K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 556.0
HFD2_k127_5761409_1 Mandelate racemase muconate lactonizing enzyme K01683,K01684 GO:0000287,GO:0003674,GO:0005488,GO:0043167,GO:0043169,GO:0046872 4.2.1.5,4.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 391.0
HFD2_k127_5761409_2 Aldo Keto reductase - - - 0.000000000000000000000000000000000000000000000000000000001471 212.0
HFD2_k127_5761409_3 SnoaL-like domain - - - 0.0000000000000000000000000000000002701 135.0
HFD2_k127_5761409_4 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000471 108.0
HFD2_k127_5764457_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003229 333.0
HFD2_k127_5764457_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 306.0
HFD2_k127_5776034_0 - - - - 0.0000000000000000000008676 108.0
HFD2_k127_5776034_1 Putative transposase of IS4/5 family (DUF4096) K07492 - - 0.0000000000000001001 83.0
HFD2_k127_5776034_2 Pentapeptide repeats (9 copies) - - - 0.0000004301 54.0
HFD2_k127_5776034_3 Transposase - - - 0.0000006066 51.0
HFD2_k127_5776034_4 alpha/beta hydrolase fold K00433 - 1.11.1.10 0.000002439 51.0
HFD2_k127_5776062_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 423.0
HFD2_k127_5776062_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000003565 178.0
HFD2_k127_5776062_2 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000000000000000000000000001775 128.0
HFD2_k127_5776062_3 Ribbon-helix-helix protein, copG family - - - 0.000000000000000008586 86.0
HFD2_k127_578930_0 ABC 3 transport family K09819 - - 0.00000000000000000000000000000000000000000000000000000000000000003517 233.0
HFD2_k127_578930_1 ATPases associated with a variety of cellular activities K09820 - - 0.0000000000000000000000000000000000000000000000000000004904 202.0
HFD2_k127_578930_2 Belongs to the Fur family K03711,K09825 - - 0.0000000000000000000000000000000006617 137.0
HFD2_k127_578930_3 Zinc-uptake complex component A periplasmic - - - 0.00000004076 57.0
HFD2_k127_5794781_0 ABC transporter transmembrane region - - - 0.0 1121.0
HFD2_k127_5794781_1 PFAM cobalamin (vitamin B12) biosynthesis CbiX protein K03795 - 4.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008848 277.0
HFD2_k127_5794781_2 Uncharacterised ArCR, COG2043 - - - 0.00000000000000000000000000000000000000000000000000008375 194.0
HFD2_k127_5794781_3 Capsular polysaccharide biosynthesis protein CapK K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000006739 174.0
HFD2_k127_5794781_4 - - - - 0.0000000000000000000000000000004824 130.0
HFD2_k127_5794781_5 translation initiation factor activity K06996 - - 0.0000000000000000000000000000611 119.0
HFD2_k127_580159_0 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573,K03183,K07003 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008757,GO:0016278,GO:0016740,GO:0016741,GO:0032259 2.1.1.163,2.1.1.201,2.1.1.77 0.0000000000000000000000001462 110.0
HFD2_k127_580159_1 RHS Repeat - - - 0.000000000002306 68.0
HFD2_k127_5806603_0 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000122 90.0
HFD2_k127_5806603_1 Transposase and inactivated derivatives K18996 - - 0.0000000001141 74.0
HFD2_k127_5809876_0 Belongs to the HpcH HpaI aldolase family K01644,K14451,K18292 - 3.1.2.30,4.1.3.25,4.1.3.34 0.00000000000000000000000000000000000000000000002732 182.0
HFD2_k127_5809876_1 Belongs to the HpcH HpaI aldolase family K01644,K18292 - 4.1.3.25,4.1.3.34 0.00000000000000000000000000000000000000000004514 173.0
HFD2_k127_5809876_2 HpcH/HpaI aldolase/citrate lyase family K01644 - 4.1.3.34 0.000000000000000000000000000000002072 144.0
HFD2_k127_5815919_0 Transposase IS116 IS110 IS902 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 502.0
HFD2_k127_5815919_1 Amidohydrolase K07045 - - 0.00000000000000000000000000001765 125.0
HFD2_k127_582080_0 phosphosulfolactate synthase activity K08097 - 4.4.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000208 252.0
HFD2_k127_582080_1 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.0000000000000000000000000000008648 131.0
HFD2_k127_582080_2 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000004641 85.0
HFD2_k127_582080_3 NMT1-like family K02051 - - 0.0001327 53.0
HFD2_k127_5821683_0 Belongs to the ABC transporter superfamily K16202 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 327.0
HFD2_k127_5821683_1 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001267 276.0
HFD2_k127_5821683_2 ABC transporter permease K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006598 267.0
HFD2_k127_5821683_3 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006448 265.0
HFD2_k127_5821683_4 Extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000003742 143.0
HFD2_k127_5823452_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 1.14e-214 687.0
HFD2_k127_5823452_1 Prephenate dehydratase K14170 GO:0003674,GO:0003824,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000866 312.0
HFD2_k127_5823452_2 Uncharacterized protein conserved in bacteria (DUF2330) - - - 0.0000000000000000000000000000000000000000000000000000000000000000009123 247.0
HFD2_k127_5823452_3 Protein of unknown function (DUF2851) - - - 0.00000000000000000000000000000000000002318 154.0
HFD2_k127_5823452_4 Helix-turn-helix - - - 0.000000000000002244 79.0
HFD2_k127_5823476_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 1.259e-255 809.0
HFD2_k127_5823476_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006585 542.0
HFD2_k127_5823476_2 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004398 478.0
HFD2_k127_5823476_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001793 287.0
HFD2_k127_5823476_4 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000001836 194.0
HFD2_k127_5823476_5 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000002146 173.0
HFD2_k127_582579_0 SNF2 family N-terminal domain - - - 1.454e-220 698.0
HFD2_k127_582579_1 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005194 613.0
HFD2_k127_582579_2 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 469.0
HFD2_k127_582579_3 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 356.0
HFD2_k127_582579_4 SWIM zinc finger - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005963 255.0
HFD2_k127_582579_5 PFAM Phytase K01083,K01113,K01126 - 3.1.3.1,3.1.3.8,3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000001298 253.0
HFD2_k127_5831211_0 PFAM ABC transporter transmembrane region K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001395 285.0
HFD2_k127_5831211_1 Dehydrogenase reductase sdr K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003689 274.0
HFD2_k127_5831211_2 - - - - 0.0000000000000000000003308 111.0
HFD2_k127_5835782_0 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.0000000000000000000000000000000000000000000000000000000000001555 226.0
HFD2_k127_5835782_1 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000004427 130.0
HFD2_k127_5835782_2 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531,K01537,K12952 - 3.6.3.2,3.6.3.8 0.0000000000000000001033 95.0
HFD2_k127_5845291_0 Cytochrome C and Quinol oxidase polypeptide I K02274 - 1.9.3.1 1.135e-248 779.0
HFD2_k127_5845291_1 Cytochrome C oxidase subunit II, periplasmic domain K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000736 284.0
HFD2_k127_5845291_2 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) - - - 0.00000000000000000000000000000000000000000002329 172.0
HFD2_k127_5845291_3 - - - - 0.0000000000000000006369 97.0
HFD2_k127_5845291_4 - - - - 0.000002119 53.0
HFD2_k127_5847635_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234 2.7.7.6 0.0 1442.0
HFD2_k127_5847635_1 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000001565 232.0
HFD2_k127_5849790_0 response regulator - - - 0.0002801 46.0
HFD2_k127_5859935_0 PFAM amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006966 339.0
HFD2_k127_5861559_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.7.7.7 0.00000000000000000000000000000000000000000000000000000001412 214.0
HFD2_k127_5861559_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000009188 118.0
HFD2_k127_5861559_2 Tellurite resistance protein TehB - - - 0.00000000000000206 79.0
HFD2_k127_5861559_3 Mannose-6-phosphate isomerase K01485 - 3.5.4.1 0.000002669 56.0
HFD2_k127_5872847_0 Glycosyltransferases involved in cell wall biogenesis-like protein - - - 0.000000000000000000000001452 119.0
HFD2_k127_5874871_0 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 300.0
HFD2_k127_5874871_1 TIGRFAM phosphate phosphite phosphonate ABC transporters, periplasmic binding protein K02044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 299.0
HFD2_k127_5874871_2 ATPases associated with a variety of cellular activities K02041 - 3.6.3.28 0.00000000000000000000000000000000000000000000000000000000000000000008106 241.0
HFD2_k127_5874871_3 Histidine kinase A domain protein - - - 0.00000000000000000000000000000000000004199 152.0
HFD2_k127_5874871_4 PFAM binding-protein-dependent transport systems inner membrane component K02042 - - 0.00000000000000000000000003261 115.0
HFD2_k127_5877345_0 3-beta hydroxysteroid dehydrogenase/isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 493.0
HFD2_k127_5877345_1 PFAM lipopolysaccharide biosynthesis protein K08253 - 2.7.10.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000007048 287.0
HFD2_k127_5877345_2 polysaccharide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002479 263.0
HFD2_k127_5877345_3 Glycosyl transferase WecB/TagA/CpsF family K05946 - 2.4.1.187 0.0000000000000000000000000000000000000000000000000000000000000000005017 257.0
HFD2_k127_5877345_4 PFAM O-Antigen ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000003913 240.0
HFD2_k127_5877345_5 Bacterial sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000004081 211.0
HFD2_k127_5877345_6 Protein of unknown function (DUF4012) - - - 0.000000000000000000000000000000000000000000000000000004539 214.0
HFD2_k127_5877345_7 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000344 154.0
HFD2_k127_5877345_8 Sortase family - - - 0.000000000000000000000000001407 130.0
HFD2_k127_5883279_0 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005936 308.0
HFD2_k127_5883279_1 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 299.0
HFD2_k127_5884910_0 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002456 247.0
HFD2_k127_5884910_1 Maleate cis-trans isomerase K01799 - 5.2.1.1 0.000000000000000001812 86.0
HFD2_k127_5901946_0 MmgE PrpD family protein - - - 0.0000000000000000000000000000000000000000000000000000000006877 214.0
HFD2_k127_5907986_1 cellulose binding - - - 0.00000000000000008441 89.0
HFD2_k127_5907986_2 - - - - 0.000000000000002189 87.0
HFD2_k127_5909901_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 462.0
HFD2_k127_5909901_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004575 415.0
HFD2_k127_5909901_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004455,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022607,GO:0036094,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 372.0
HFD2_k127_5909901_3 'ABC-type dipeptide oligopeptide nickel transport K02034,K15582 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 339.0
HFD2_k127_5912108_0 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000475 286.0
HFD2_k127_5912108_1 Major facilitator superfamily K08161 - - 0.00000000000000001119 94.0
HFD2_k127_5924080_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000001049 159.0
HFD2_k127_5924080_1 Nipsnap homolog - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000001069 107.0
HFD2_k127_5924080_2 Extracellular solute-binding protein, family 5 K02035 - - 0.00000000000000000001113 101.0
HFD2_k127_594123_0 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 399.0
HFD2_k127_594123_1 Histidine kinase-like ATPases - - - 0.0000000005917 66.0
HFD2_k127_5943893_0 glutamine synthetase K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 611.0
HFD2_k127_5943893_1 PucR C-terminal helix-turn-helix domain K09684 - - 0.0000000000000000000000000000000000000000000000000000000001307 224.0
HFD2_k127_5943893_2 regulatory protein RecX K03565 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000001867 83.0
HFD2_k127_5945176_0 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002925 229.0
HFD2_k127_5945176_1 Glyoxalase-like domain K08234 - - 0.000000000000000000000000000000000000000000000000000000000000001517 225.0
HFD2_k127_5945176_2 transmembrane transporter activity - - - 0.000000008821 64.0
HFD2_k127_5945630_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003347 314.0
HFD2_k127_5945630_1 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000325 115.0
HFD2_k127_5945630_2 Helix-turn-helix domain protein - - - 0.0001013 51.0
HFD2_k127_5945630_3 YtxH-like protein - - - 0.0001412 49.0
HFD2_k127_5951588_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531,K01537,K12952 - 3.6.3.2,3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 342.0
HFD2_k127_5951588_1 Belongs to the LarC family K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000004077 192.0
HFD2_k127_5953317_0 Natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009916 437.0
HFD2_k127_5953317_1 Acts as a magnesium transporter K06213 GO:0000287,GO:0003674,GO:0005488,GO:0005515,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015693,GO:0030001,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0051179,GO:0051234,GO:0070838,GO:0072511 - 0.000000004753 60.0
HFD2_k127_5954816_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 3.123e-227 719.0
HFD2_k127_5954816_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000001564 84.0
HFD2_k127_5973050_0 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000001936 137.0
HFD2_k127_5973050_1 Glycosyl transferases group 1 - - - 0.0000000000000000000003173 111.0
HFD2_k127_5979904_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain K03520,K11177 - 1.17.1.4,1.2.5.3 4.678e-254 806.0
HFD2_k127_5979904_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 1.504e-206 666.0
HFD2_k127_5979904_2 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 364.0
HFD2_k127_5979904_3 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000123 257.0
HFD2_k127_5979904_4 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000002968 235.0
HFD2_k127_5979904_5 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000002264 198.0
HFD2_k127_5979904_6 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000003869 123.0
HFD2_k127_5979904_7 extracellular solute-binding protein, family 1 K05772 - - 0.00000000000002978 73.0
HFD2_k127_5979904_8 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000003377 76.0
HFD2_k127_5979904_9 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000001497 61.0
HFD2_k127_5996487_0 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) - - - 0.0000000000000000000000000000000000000000000000002724 187.0
HFD2_k127_5996487_1 Heme copper-type cytochrome quinol oxidase subunit 3 K02276 - 1.9.3.1 0.000000000000000000000000000000000003859 145.0
HFD2_k127_5996487_2 SCO1/SenC K07152 - - 0.00000000000006352 76.0
HFD2_k127_6009802_0 nitrite transmembrane transporter activity K02575 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000865 441.0
HFD2_k127_6009802_1 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000001999 252.0
HFD2_k127_6013533_0 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000123 257.0
HFD2_k127_6013533_1 Glycine oxidase K03153 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0036094,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043436,GO:0043799,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0072527,GO:0072528,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.4.3.19 0.0000000000000000000000000000004584 131.0
HFD2_k127_6013533_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585,K07799 - - 0.0000000000000000000965 105.0
HFD2_k127_6013533_3 Putative cell wall binding repeat 2 K01448 - 3.5.1.28 0.00000000008782 72.0
HFD2_k127_6013533_4 Luciferase-like monooxygenase - - - 0.0008381 44.0
HFD2_k127_6014221_0 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 357.0
HFD2_k127_6014221_1 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 342.0
HFD2_k127_6014221_2 PFAM DinB family protein - - - 0.00000000000000000000000000000000000407 149.0
HFD2_k127_6014221_3 carboxymuconolactone decarboxylase - - - 0.00000000000000000000000523 113.0
HFD2_k127_6035624_0 ABC transporter, transmembrane region K06147,K06148,K18889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 417.0
HFD2_k127_6035624_1 ABC transporter, transmembrane region K06147,K18890 - - 0.00000000000000000000000000000000000000000000000000000000000000000002329 253.0
HFD2_k127_6040072_0 COG1472 Beta-glucosidase-related glycosidases K01207 - 3.2.1.52 0.0000000000000000000000000000000124 138.0
HFD2_k127_6040072_1 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.000000000000000000000000000001458 126.0
HFD2_k127_6047556_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000003208 126.0
HFD2_k127_6051997_0 AAA family ATPase, CDC48 subfamily K13525 - - 5.321e-214 688.0
HFD2_k127_6051997_1 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004982 286.0
HFD2_k127_6051997_2 NUDIX domain - - - 0.00000000000000000000000000002626 122.0
HFD2_k127_6058410_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652,K03852 - 2.2.1.6,2.3.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007204 556.0
HFD2_k127_6058410_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 325.0
HFD2_k127_6058410_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000001231 113.0
HFD2_k127_6058410_3 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000005387 97.0
HFD2_k127_6060129_0 Glycosyltransferases involved in cell wall biogenesis-like protein - - - 0.00000000000000000000000000000000001183 154.0
HFD2_k127_6060129_1 Arylsulfotransferase (ASST) - - - 0.00000000000000009066 94.0
HFD2_k127_6060129_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000313 56.0
HFD2_k127_6060860_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 311.0
HFD2_k127_6060860_1 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000006102 95.0
HFD2_k127_6060860_2 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000001372 94.0
HFD2_k127_6079010_0 Transposase DDE domain group 1 - - - 0.000000000000000000000000002316 127.0
HFD2_k127_6082347_0 Luciferase-like monooxygenase K14733 - 1.14.13.107 3.769e-232 722.0
HFD2_k127_6082347_1 Acyl-CoA dehydrogenase, C-terminal domain K22027 - 1.14.13.235 0.0000000000000000000000000000000000008347 146.0
HFD2_k127_6082347_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0006343 43.0
HFD2_k127_6084953_0 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000004027 231.0
HFD2_k127_6084953_1 PFAM glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000007627 229.0
HFD2_k127_6084953_2 DinB family - - - 0.0000000000000000000000000000000000000000000136 169.0
HFD2_k127_6084953_3 ADP-L-glycero-beta-D-manno-heptose biosynthetic process K03272 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000002839 158.0
HFD2_k127_6092831_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000005227 214.0
HFD2_k127_6092831_1 Protein involved in formate dehydrogenase formation K02380 - - 0.0000000000000000000000000000000000000000001872 164.0
HFD2_k127_6092831_2 - - - - 0.0000000000000000000000000000000004411 136.0
HFD2_k127_6095034_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 383.0
HFD2_k127_6108179_0 acetyltransferase - - - 0.0000000000000000000000000000000000000000000003553 179.0
HFD2_k127_6108179_1 - - - - 0.000000000000000000000000000000000000000001343 173.0
HFD2_k127_6108518_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 604.0
HFD2_k127_6108518_1 Acyclic terpene utilisation family protein AtuA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000657 279.0
HFD2_k127_6108518_2 Acyclic terpene utilisation family protein AtuA - - - 0.0000000000000000000000000000000000000000000000000000000003453 210.0
HFD2_k127_6108518_3 Domain of unknown function (DUF4387) - - - 0.00000000000000000000000000006233 126.0
HFD2_k127_6108518_4 Protein of unknown function (DUF3105) - - - 0.0000000000000000000000000003953 130.0
HFD2_k127_6108518_5 Phosphomethylpyrimidine kinase - - - 0.000000000000000000000001901 106.0
HFD2_k127_6108518_6 PFAM TadE family protein - - - 0.000000000000000000008181 106.0
HFD2_k127_6108518_7 PFAM TadE family protein - - - 0.0000000000000000007101 92.0
HFD2_k127_6108518_8 PFAM TadE family protein - - - 0.00000000004516 73.0
HFD2_k127_6121030_0 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009477 481.0
HFD2_k127_6129910_0 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000001909 80.0
HFD2_k127_6129910_1 major facilitator superfamily - - - 0.000000000001006 80.0
HFD2_k127_6129910_2 Domain of unknown function (DUF4105) - - - 0.00005869 48.0
HFD2_k127_6132987_0 NMT1-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 391.0
HFD2_k127_6132987_1 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000005584 185.0
HFD2_k127_6132987_2 Belongs to the HpcH HpaI aldolase family - - - 0.0000000000000000000000000000000000000000000000002026 180.0
HFD2_k127_6132987_3 Belongs to the HpcH HpaI aldolase family - - - 0.00000000000000000000000000000000007011 140.0
HFD2_k127_6132987_4 PFAM amidohydrolase - - - 0.000000001551 61.0
HFD2_k127_6133463_0 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000005151 251.0
HFD2_k127_6133463_1 MFS/sugar transport protein K16211 - - 0.00000000000006197 85.0
HFD2_k127_6133463_3 Rhodanese Homology Domain - - - 0.0005081 44.0
HFD2_k127_6134595_0 Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007552 336.0
HFD2_k127_6134595_1 AAA domain, putative AbiEii toxin, Type IV TA system K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002342 280.0
HFD2_k127_6134595_2 homolog of gamma-carboxymuconolactone decarboxylase subunit K01607 - 4.1.1.44 0.000000000000000536 83.0
HFD2_k127_6142528_0 histidyl-tRNA aminoacylation K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004661 456.0
HFD2_k127_6142528_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006474 396.0
HFD2_k127_6142528_2 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493,K07320 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006304,GO:0006305,GO:0006306,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009007,GO:0009008,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0032775,GO:0034641,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044728,GO:0046483,GO:0071704,GO:0090304,GO:0140096,GO:0140097,GO:1901360,GO:1901564 2.1.1.297,2.1.1.298 0.000000000000000000000000000000000000000000000000000003026 200.0
HFD2_k127_6143620_0 SMART ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001328 258.0
HFD2_k127_6143620_1 PFAM response regulator receiver - - - 0.00000000000000000001567 101.0
HFD2_k127_6145554_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 560.0
HFD2_k127_6145554_1 Binding-protein-dependent transport system inner membrane component K02033,K15585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 411.0
HFD2_k127_6145554_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003594 402.0
HFD2_k127_6145554_3 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K00320 - 1.5.98.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 389.0
HFD2_k127_6145554_4 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006686 326.0
HFD2_k127_6145554_5 Argininosuccinate lyase C-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004583 321.0
HFD2_k127_6145554_6 Class II Aldolase and Adducin N-terminal domain - - - 0.00000000000000000000000000000000000000197 153.0
HFD2_k127_6145554_7 Class II Aldolase and Adducin N-terminal domain - - - 0.0000000000000000000000006589 113.0
HFD2_k127_6145882_0 Bacterial membrane protein YfhO - - - 0.00000000000000000000000000000000000000000000000000000000000000002621 246.0
HFD2_k127_6147045_0 Chromate transporter K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 508.0
HFD2_k127_614813_0 F420-dependent oxidoreductase, MSMEG_3544 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001013 284.0
HFD2_k127_614813_1 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000002055 171.0
HFD2_k127_614813_2 EamA-like transporter family - - - 0.00000000000000009719 91.0
HFD2_k127_6154995_0 Methyltransferase small domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 422.0
HFD2_k127_6154995_1 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000002442 245.0
HFD2_k127_6154995_2 PFAM GCN5-related N-acetyltransferase K00619 - 2.3.1.1 0.000000000000000000000000000000000000000000000000000000001003 207.0
HFD2_k127_6154995_3 Cation efflux family - - - 0.00000000000000000000000000000000000000000000000000000009048 205.0
HFD2_k127_6154995_4 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000002051 126.0
HFD2_k127_6154995_5 L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000001598 76.0
HFD2_k127_6156598_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 5.498e-216 681.0
HFD2_k127_6156598_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016020,GO:0016053,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.33,4.2.1.35 0.00000006948 54.0
HFD2_k127_616376_0 Replication protein C K18996 - - 0.0000000000000000000000000000000000000000000000000000000000000000003822 243.0
HFD2_k127_6168677_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 2.983e-293 912.0
HFD2_k127_6168677_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 424.0
HFD2_k127_6168677_2 HD domain - - - 0.0000000000000000000000000000000000000000000000000000003556 203.0
HFD2_k127_6168677_3 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000001198 196.0
HFD2_k127_6168677_4 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000002228 132.0
HFD2_k127_6168677_5 - - - - 0.00000000000000000000002915 112.0
HFD2_k127_6168677_6 gluconolactonase activity K07214,K09689,K14274 - 3.6.3.38 0.000000003196 68.0
HFD2_k127_6168677_7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K03503 - - 0.00001533 55.0
HFD2_k127_6170265_0 PAS fold - - - 0.00000000000000000000000000000000000000000001839 180.0
HFD2_k127_6170265_1 Drug metabolite transporter (DMT) superfamily - - - 0.000000000000000001165 97.0
HFD2_k127_6170265_2 Von Willebrand and RING finger domain protein - - - 0.0007359 52.0
HFD2_k127_6170907_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 535.0
HFD2_k127_6170907_1 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000007547 206.0
HFD2_k127_6170907_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000005284 190.0
HFD2_k127_6170907_3 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000002585 189.0
HFD2_k127_6170931_0 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000008779 209.0
HFD2_k127_6170931_1 Cysteine-rich secretory protein family - - - 0.0000000000000000004394 99.0
HFD2_k127_6206054_0 Short-chain dehydrogenase reductase SDR K08679 - 5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 345.0
HFD2_k127_6206054_1 Glycosyltransferase like family 2 K10012 - 2.4.2.53 0.000000000000000000000000000000001635 134.0
HFD2_k127_6210100_0 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007389 451.0
HFD2_k127_6210100_1 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000003342 263.0
HFD2_k127_6216583_0 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.0000000000000000000000000000000000000000000000000000000000000004965 234.0
HFD2_k127_6216583_1 6-O-methylguanine DNA methyltransferase, DNA binding domain K07443 - - 0.00000000000000000000001143 109.0
HFD2_k127_6216583_2 cell redox homeostasis K02199 - - 0.00000000000000001075 92.0
HFD2_k127_6222279_0 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 537.0
HFD2_k127_6222279_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000001683 212.0
HFD2_k127_6222279_2 gualylate cyclase - - - 0.0000000000000000000000002814 107.0
HFD2_k127_6222279_3 activity, protein serine threonine kinase activity, protein-tyrosine kinase activity, ATP binding, regulation of transcription, DNA-dependent, protein amino acid phosphorylation K08282 - 2.7.11.1 0.000000000000000004259 89.0
HFD2_k127_6231396_0 Aminotransferase class I and II K14155 - 4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000002522 237.0
HFD2_k127_6231396_1 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000001257 244.0
HFD2_k127_6249663_0 TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family - - - 0.000000000000000000000000000267 125.0
HFD2_k127_6249663_1 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000414 73.0
HFD2_k127_6249663_2 PFAM Cupin 2, conserved barrel - - - 0.0002682 51.0
HFD2_k127_6250242_0 DNA methylase K00571,K00590 - 2.1.1.113,2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000004784 247.0
HFD2_k127_6250242_1 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000004183 124.0
HFD2_k127_6251923_0 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007028 274.0
HFD2_k127_6251923_1 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000002321 162.0
HFD2_k127_6282009_0 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005117 310.0
HFD2_k127_6282009_1 acyl-CoA dehydrogenase - - - 0.000001011 57.0
HFD2_k127_6294192_0 peptidase activity - - - 0.0000000000000000009644 99.0
HFD2_k127_6297092_0 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000008137 159.0
HFD2_k127_6297092_1 - - - - 0.0000000000000000000000000000005523 139.0
HFD2_k127_6297092_2 Phage tail protein (Tail_P2_I) - - - 0.00000000000000000001121 102.0
HFD2_k127_6297092_3 Glycosyl transferase family 2 - - - 0.000000002415 60.0
HFD2_k127_6304834_0 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000003133 187.0
HFD2_k127_6304834_1 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.0000000000000000000000000000000000000001701 154.0
HFD2_k127_6304834_2 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000008487 136.0
HFD2_k127_631818_0 Extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004585 316.0
HFD2_k127_631818_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001028 289.0
HFD2_k127_631818_2 PFAM ABC transporter related K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007811 255.0
HFD2_k127_631818_3 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000007169 227.0
HFD2_k127_631818_4 amino acid K01995,K10822 - 3.6.3.22 0.0000000000000000000000000000000000000000000000000000000005652 215.0
HFD2_k127_631818_5 DNA mediated transformation K04096 - - 0.0000000000000000000000000000000000000000000002063 184.0
HFD2_k127_631818_6 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000000000003289 154.0
HFD2_k127_631818_7 FCD - - - 0.000000000000000000000000000000000000009745 155.0
HFD2_k127_631818_8 L-phenylalanine transmembrane transporter activity K01998 - - 0.000000000000000000000000006229 114.0
HFD2_k127_6323705_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 430.0
HFD2_k127_6323705_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 411.0
HFD2_k127_6323705_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006337 310.0
HFD2_k127_6323705_3 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000002227 140.0
HFD2_k127_6323705_4 Cell division protein FtsQ K03589 - - 0.0000000005957 70.0
HFD2_k127_6324560_0 Belongs to the mandelate racemase muconate lactonizing enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006198 265.0
HFD2_k127_6324560_1 acyl-CoA dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000007046 210.0
HFD2_k127_6324560_2 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K12661 - 4.2.1.90 0.0000000000000000000000003374 106.0
HFD2_k127_6324560_3 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.0000000000000000000000006143 117.0
HFD2_k127_6343248_0 Glucokinase K00845 GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0051156,GO:0071704,GO:1901135 2.7.1.2 0.00000348 53.0
HFD2_k127_6351729_0 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000004874 59.0
HFD2_k127_6351794_0 Glycosyltransferases involved in cell wall biogenesis-like protein - - - 0.000000000000000000000000005044 127.0
HFD2_k127_6351794_1 Belongs to the phosphoglycerate mutase family - - - 0.00003119 51.0
HFD2_k127_6359745_0 PFAM NHL repeat containing protein - - - 0.000000000000000000000000000000000000007639 157.0
HFD2_k127_6359745_1 2-keto-4-pentenoate hydratase K01617 - 4.1.1.77 0.0000000000000000007296 87.0
HFD2_k127_6359745_2 PFAM Major Facilitator Superfamily K19577 - - 0.000000001739 68.0
HFD2_k127_636085_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 GO:0000049,GO:0000166,GO:0000287,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004828,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006434,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0010467,GO:0016020,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046983,GO:0070905,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003518 440.0
HFD2_k127_636085_1 PFAM metal-dependent phosphohydrolase, HD sub domain K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 423.0
HFD2_k127_636085_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 336.0
HFD2_k127_6372987_0 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 457.0
HFD2_k127_6372987_1 Inosine-uridine preferring nucleoside hydrolase K01250 - - 0.000000000000000000000000000002994 132.0
HFD2_k127_6372987_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000001318 108.0
HFD2_k127_6372987_3 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000005893 62.0
HFD2_k127_6380934_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 475.0
HFD2_k127_6380934_1 Metallo-beta-lactamase superfamily K05555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 416.0
HFD2_k127_6380934_2 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000005516 243.0
HFD2_k127_6381311_0 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K04091 - 1.14.14.5 0.000000000000000000000000000000000000000000000000000003509 196.0
HFD2_k127_6381311_1 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000001448 124.0
HFD2_k127_6393215_0 4Fe-4S binding domain K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007809 413.0
HFD2_k127_6393215_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000001118 184.0
HFD2_k127_6393215_2 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000001898 190.0
HFD2_k127_6393215_3 Protein involved in formate dehydrogenase formation K02380 - - 0.000000727 57.0
HFD2_k127_6393215_4 - - - - 0.000002041 51.0
HFD2_k127_6397451_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07306,K08352 - 1.8.5.3,1.8.5.5 0.000000000000000002344 91.0
HFD2_k127_6397451_1 Parallel beta-helix repeats - - - 0.000000000000000007631 94.0
HFD2_k127_6402088_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000001326 142.0
HFD2_k127_6404679_0 Glycosyltransferases involved in cell wall biogenesis-like protein - - - 0.000000000000000000000000000000007805 145.0
HFD2_k127_6407722_0 CorA-like Mg2+ transporter protein K03284 - - 0.000000000000000000000000000000000000000000000000007554 189.0
HFD2_k127_6407722_1 Glycosyltransferases involved in cell wall biogenesis-like protein - - - 0.0000000000000000000000001207 123.0
HFD2_k127_6407722_2 - - - - 0.00000000000000000000000219 110.0
HFD2_k127_640834_0 PAC2 family - - - 0.00000000000000000000000000000000000000000000000000000009847 208.0
HFD2_k127_640834_1 N-acetylglucosaminylinositol deacetylase activity - - - 0.00000000000000002817 86.0
HFD2_k127_6411623_0 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008186 391.0
HFD2_k127_6411623_1 Periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 303.0
HFD2_k127_6411623_2 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 297.0
HFD2_k127_6411623_3 PFAM Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001245 244.0
HFD2_k127_6411623_4 PAC2 family - - - 0.000000000000000000000000000000000000000000000000000000000000000001526 237.0
HFD2_k127_6411623_5 protein histidine kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000004901 237.0
HFD2_k127_6411623_6 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000001375 204.0
HFD2_k127_6411623_7 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.00000000000000000000000000000000000000000008813 169.0
HFD2_k127_6425828_0 PFAM Glycosyl transferase, group 1 K13057 - 2.4.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007888 507.0
HFD2_k127_6425828_1 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000002464 241.0
HFD2_k127_6429114_0 Extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000005253 184.0
HFD2_k127_6433590_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000001051 243.0
HFD2_k127_6433590_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000001608 171.0
HFD2_k127_6438575_0 PFAM CobN magnesium chelatase K02230 - 6.6.1.2 1.625e-198 629.0
HFD2_k127_6438575_1 AAA domain (dynein-related subfamily) K03404,K03405 - 6.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009671 398.0
HFD2_k127_6439323_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00018,K00058 - 1.1.1.29,1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000542 289.0
HFD2_k127_6439844_0 Molecular chaperone. Has ATPase activity K04079 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008396 446.0
HFD2_k127_6439844_1 Histidine kinase K07675 - 2.7.13.3 0.00000000000000000000000002438 112.0
HFD2_k127_6444442_0 - K07234 - - 0.0000000000000000000000000000000000000000000000000000000007196 218.0
HFD2_k127_6444442_1 - - - - 0.0000000000000000000000008075 106.0
HFD2_k127_6444442_2 Peptidase A4 family - - - 0.000000000000000000007812 97.0
HFD2_k127_6446283_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 379.0
HFD2_k127_6446283_1 - - - - 0.00000000000000000000000009743 111.0
HFD2_k127_6446283_2 xanthine dehydrogenase activity K00087,K12528 - 1.17.1.4 0.00000001223 57.0
HFD2_k127_6446283_3 TIGRFAM clan AA aspartic protease, AF_0612 family - - - 0.00001745 50.0
HFD2_k127_6446283_4 pathogenesis - - - 0.00003881 55.0
HFD2_k127_6446690_0 Pfam:DUF1446 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003805 499.0
HFD2_k127_6446690_1 Acyl-CoA dehydrogenase, C-terminal domain K22027 - 1.14.13.235 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005647 301.0
HFD2_k127_6446690_2 Belongs to the SfsA family K06206 - - 0.00000000000000000000000002466 114.0
HFD2_k127_6446690_3 Domain of unknown function (DUF4387) - - - 0.00000000000000000001168 93.0
HFD2_k127_6446690_4 - - - - 0.000000000000005881 86.0
HFD2_k127_6471041_0 DNA recombination K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000001543 238.0
HFD2_k127_6471041_1 COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily - - - 0.0000000000000000006149 91.0
HFD2_k127_6471041_2 Luciferase-like monooxygenase - - - 0.00007765 49.0
HFD2_k127_6473396_0 succinyl-diaminopimelate desuccinylase activity K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004896 474.0
HFD2_k127_6473396_1 Glycosyl transferase 4-like domain K08256 - 2.4.1.345 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 369.0
HFD2_k127_6473396_2 PFAM peptidase S58, DmpA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007673 301.0
HFD2_k127_6473396_3 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000007471 222.0
HFD2_k127_6473396_4 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.00000000000000000000000000000000009132 141.0
HFD2_k127_6473396_5 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000008765 132.0
HFD2_k127_6473396_6 Bacterial lipid A biosynthesis acyltransferase K02517,K22311 - 2.3.1.241,2.3.1.265 0.00000000000000000000000011 113.0
HFD2_k127_6476620_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1367.0
HFD2_k127_6476620_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002843 445.0
HFD2_k127_6482795_0 Probable cobalt transporter subunit (CbtA) - - - 0.000000000000000000000000000000000155 141.0
HFD2_k127_6482795_1 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.00000000004286 63.0
HFD2_k127_6482795_2 Probable cobalt transporter subunit (CbtB) - - - 0.0002845 49.0
HFD2_k127_649190_0 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000001587 159.0
HFD2_k127_649190_1 peptidase - - - 0.0000000000000000000000000000000000003782 151.0
HFD2_k127_649190_2 Transcriptional regulatory protein, C terminal - - - 0.0000000000005832 68.0
HFD2_k127_650681_0 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006438 264.0
HFD2_k127_650681_1 Extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000002036 231.0
HFD2_k127_650681_2 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000001481 166.0
HFD2_k127_650681_3 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000005728 156.0
HFD2_k127_6516649_0 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000004326 76.0
HFD2_k127_6516649_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000001143 68.0
HFD2_k127_6516649_2 Luciferase-like monooxygenase - - - 0.000009598 49.0
HFD2_k127_6516649_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00001515 57.0
HFD2_k127_651749_0 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 429.0
HFD2_k127_651749_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003911 317.0
HFD2_k127_651749_2 Psort location Cytoplasmic, score 7.50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007238 261.0
HFD2_k127_651749_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000001731 178.0
HFD2_k127_651749_4 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000008548 90.0
HFD2_k127_6520386_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004247 400.0
HFD2_k127_6520386_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007491 380.0
HFD2_k127_6528257_0 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000000000000000000000000000000000000000000000001961 245.0
HFD2_k127_6528257_1 - - - - 0.00000000000003866 79.0
HFD2_k127_6530367_0 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000008356 145.0
HFD2_k127_6530367_1 phospholipid phosphatase K19302 - 3.6.1.27 0.0000000000000000000000000000008313 132.0
HFD2_k127_6530367_2 ABC-type multidrug transport system ATPase and permease K18890 - - 0.000000000000001519 77.0
HFD2_k127_6535767_0 PFAM Lipase, class 3 K01046 - 3.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000003729 250.0
HFD2_k127_6535767_1 Protein of unknown function (DUF3105) - - - 0.000000000000000000000001462 117.0
HFD2_k127_6535767_2 Phospholipid-binding domain protein - - - 0.000000000000000007763 95.0
HFD2_k127_6537188_0 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004057 421.0
HFD2_k127_6537188_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000126 166.0
HFD2_k127_6543358_0 UDP binding domain K13015 - 1.1.1.136 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005298 406.0
HFD2_k127_6543358_1 sialic acid K05304 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006055,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0008781,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016740,GO:0016765,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046381,GO:0046483,GO:0047444,GO:0055086,GO:0070085,GO:0070567,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901576 2.5.1.132,2.5.1.56,2.5.1.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003735 304.0
HFD2_k127_6543358_2 PFAM NAD dependent epimerase dehydratase family K01709 - 4.2.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000009962 259.0
HFD2_k127_6543358_3 3-deoxy-manno-octulosonate-8-phosphatase activity K00983,K03270 - 2.7.7.43,3.1.3.45 0.00000000000000000000000000000000000000000000000000000000000001793 224.0
HFD2_k127_6543358_4 N-acetylglucosaminylinositol deacetylase activity - - - 0.0000000000000000000000000000000000000000000000000000002248 200.0
HFD2_k127_6543358_5 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008781,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016311,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016791,GO:0019143,GO:0033692,GO:0034637,GO:0034645,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0070567,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 3.1.3.45 0.0000000000000000000000000000000000000000006178 163.0
HFD2_k127_654557_0 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 314.0
HFD2_k127_654557_1 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003724 295.0
HFD2_k127_654557_2 PFAM phospholipase Carboxylesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005696 285.0
HFD2_k127_6550740_0 Binding-protein-dependent transport system inner membrane component K15581 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 299.0
HFD2_k127_6550740_1 N-terminal TM domain of oligopeptide transport permease C K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000002203 231.0
HFD2_k127_6550740_2 PFAM extracellular solute-binding protein, family 5 K15580 - - 0.0000001271 55.0
HFD2_k127_6551298_0 Aminotransferase class I and II K00812,K00841,K10907 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001923 282.0
HFD2_k127_6551298_1 Homeodomain-like domain - - - 0.0000000000000003878 81.0
HFD2_k127_6551298_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K12256 - 2.6.1.113 0.000000005419 57.0
HFD2_k127_6555061_0 homoserine kinase activity K02204 - 2.7.1.39 0.0 1187.0
HFD2_k127_6555061_1 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 406.0
HFD2_k127_6555061_2 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004275 321.0
HFD2_k127_6560481_0 Adenylate cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 385.0
HFD2_k127_6560481_1 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000472 372.0
HFD2_k127_6575599_0 Belongs to the peptidase S16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004601 615.0
HFD2_k127_6575599_1 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005433 257.0
HFD2_k127_6575599_2 Oxidoreductase family, C-terminal alpha/beta domain K19181 - 1.1.1.292 0.00000000000000000000000000000000000000000000001234 185.0
HFD2_k127_6591874_0 Protein of unknown function (DUF3500) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001188 283.0
HFD2_k127_6591874_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00122,K00335,K17992 - 1.12.1.3,1.17.1.9,1.6.5.3 0.00000000000000000000000000000003097 130.0
HFD2_k127_6591874_2 Nitronate monooxygenase K00459 - 1.13.12.16 0.0000004489 52.0
HFD2_k127_6607544_0 M COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.00000000000000000000000000000000000000000000000000000000000000003921 233.0
HFD2_k127_6607544_1 - - - - 0.000000000000000000000000000000000008433 145.0
HFD2_k127_6610298_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000001283 240.0
HFD2_k127_6610298_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K05580 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000007674 192.0
HFD2_k127_6610298_2 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000001159 86.0
HFD2_k127_6625657_0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K15830 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006019 466.0
HFD2_k127_6625657_1 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000001784 211.0
HFD2_k127_6625657_2 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000008634 140.0
HFD2_k127_6625657_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K12143 - 1.6.5.3 0.000000003243 63.0
HFD2_k127_6627473_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 391.0
HFD2_k127_6632226_0 Spermidine synthase tetramerisation domain K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000001821 253.0
HFD2_k127_6632226_1 diaminopimelate decarboxylase activity K01581 - 4.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000001669 246.0
HFD2_k127_6637901_0 5'-nucleotidase, C-terminal domain K01081 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000474 440.0
HFD2_k127_6645362_0 Cache domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 530.0
HFD2_k127_6645362_2 - - - - 0.00006775 53.0
HFD2_k127_6649283_0 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000419 282.0
HFD2_k127_6649283_1 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000001296 199.0
HFD2_k127_6659927_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005533 329.0
HFD2_k127_6659927_1 UbiA prenyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001949 288.0
HFD2_k127_6659927_10 Belongs to the UPF0109 family K06960 - - 0.0000000000000000008654 88.0
HFD2_k127_6659927_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000132 219.0
HFD2_k127_6659927_3 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000006164 216.0
HFD2_k127_6659927_4 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000004646 200.0
HFD2_k127_6659927_5 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000001648 172.0
HFD2_k127_6659927_6 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000509 147.0
HFD2_k127_6659927_7 ribosomal protein l17 K02879 - - 0.0000000000000000000000000000000000002585 143.0
HFD2_k127_6659927_8 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000006774 129.0
HFD2_k127_6659927_9 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000000000000000002566 107.0
HFD2_k127_6660161_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 476.0
HFD2_k127_6660161_1 PFAM PfkB domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000001138 246.0
HFD2_k127_6660161_2 Forkhead associated domain - - - 0.00000000000000000000000000000000000000224 151.0
HFD2_k127_6660161_3 PFAM response regulator receiver K11443 - - 0.0000000000000000000000000000000000000372 146.0
HFD2_k127_6670582_0 cellulose binding - - - 0.000000000000000000000000000001351 135.0
HFD2_k127_6670582_1 TCP-1/cpn60 chaperonin family - - - 0.0000000000001228 76.0
HFD2_k127_667932_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005966 547.0
HFD2_k127_667932_1 Glycosyltransferase like family 2 K10012 - 2.4.2.53 0.0000000000000000000000000000000000000000000000000000000000000000000001929 243.0
HFD2_k127_667932_2 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000001927 157.0
HFD2_k127_6682371_0 alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 340.0
HFD2_k127_6682371_1 Amidohydrolase family K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000007745 271.0
HFD2_k127_6685111_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01577,K01652,K03852 - 2.2.1.6,2.3.3.15,4.1.1.8 6.42e-201 640.0
HFD2_k127_6685111_1 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567,K10778 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008695 427.0
HFD2_k127_6685111_2 Oxygenase, catalysing oxidative methylation of damaged DNA K09990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005736 317.0
HFD2_k127_6685111_3 PFAM PQQ enzyme repeat - - - 0.000000000000000000000000000000000000000000000000002105 200.0
HFD2_k127_669007_0 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000755 515.0
HFD2_k127_669007_1 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000004322 211.0
HFD2_k127_669007_2 alginic acid biosynthetic process - - - 0.0000000000000000000001334 100.0
HFD2_k127_669007_3 Major facilitator Superfamily K18567 - - 0.00000000000000001542 96.0
HFD2_k127_6699517_0 COG3335 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 286.0
HFD2_k127_6699517_1 RHS Repeat - - - 0.00000000000000000000000000000000004306 143.0
HFD2_k127_6699517_2 DDE superfamily endonuclease - - - 0.0000000000000000000000000000002584 128.0
HFD2_k127_670318_0 COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 475.0
HFD2_k127_670318_1 Dehydrogenase E1 component K00166 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 331.0
HFD2_k127_670318_2 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000172 255.0
HFD2_k127_670318_3 peptidoglycan-binding protein, lysm - - - 0.0000000001313 69.0
HFD2_k127_670318_4 Protein of unknown function (DUF1015) - - - 0.00000006864 53.0
HFD2_k127_6712201_0 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000009464 165.0
HFD2_k127_6712201_1 Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides K03478 - 3.5.1.105 0.0000000000000000000000000000000001873 146.0
HFD2_k127_6712201_2 Acetyltransferase (GNAT) domain - - - 0.00000000000001188 81.0
HFD2_k127_6713266_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 351.0
HFD2_k127_6713266_1 Domain of unknown function (DUF305) - - - 0.00000000004878 73.0
HFD2_k127_6715206_0 MOSC domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001857 268.0
HFD2_k127_6715206_1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627 - 2.3.1.12 0.00000000000000000000000000000001064 135.0
HFD2_k127_6715206_2 Protein of unknown function (DUF1572) - - - 0.0000000000000000000001166 100.0
HFD2_k127_6724974_0 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007294 318.0
HFD2_k127_6724974_1 Extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007463 321.0
HFD2_k127_6724974_2 Extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009471 314.0
HFD2_k127_6724974_3 Binding-protein-dependent transport system inner membrane component K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000002668 243.0
HFD2_k127_6724974_4 Metal-dependent hydrolase K07043 - - 0.0002554 50.0
HFD2_k127_6725334_0 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000649 251.0
HFD2_k127_6725334_1 PFAM Integrase catalytic - - - 0.00000000000000000000000000000000000000000002074 173.0
HFD2_k127_6725334_2 PFAM Integrase catalytic - - - 0.0000000000000000000000000000005019 126.0
HFD2_k127_6725334_3 polysaccharide deacetylase - - - 0.00000000000000000000000009068 111.0
HFD2_k127_6725334_4 PFAM Luciferase-like monooxygenase - - - 0.0000000000000000003835 89.0
HFD2_k127_6725334_5 polysaccharide deacetylase K22278 - 3.5.1.104 0.0000000000006031 71.0
HFD2_k127_6732022_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004684 411.0
HFD2_k127_6732022_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015934,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031325,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000232,GO:2000234 - 0.000000000000000000000000000000000000000000000000000000000000000000000000008777 258.0
HFD2_k127_6732022_2 Forms part of the polypeptide exit tunnel K02926 - - 0.00000000000000000000000000000000000000000000000000002161 198.0
HFD2_k127_6732022_3 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000002482 168.0
HFD2_k127_6732022_4 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000001003 153.0
HFD2_k127_6732022_5 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000000000000000000000002607 118.0
HFD2_k127_6732022_6 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000105 51.0
HFD2_k127_6740423_0 major facilitator superfamily MFS_1 K08225 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005817 306.0
HFD2_k127_6740423_1 haloacid dehalogenase - - - 0.00000000000000000000000000000000000000000000000000000009727 201.0
HFD2_k127_6740423_2 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000002071 92.0
HFD2_k127_6740423_3 DJ-1/PfpI family - - - 0.000000000000001743 79.0
HFD2_k127_6740423_4 mRNA binding K07339 - - 0.0000008455 51.0
HFD2_k127_6740423_5 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000002548 59.0
HFD2_k127_67474_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002393 244.0
HFD2_k127_67474_1 Glycosyl hydrolases family 15 - - - 0.0000000000000000000000000000000000000000000000000000000002079 209.0
HFD2_k127_67474_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000003969 90.0
HFD2_k127_6761644_0 Oxidoreductase molybdopterin binding domain K07147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005448 297.0
HFD2_k127_6761644_1 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.0000000000001284 83.0
HFD2_k127_6764159_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 374.0
HFD2_k127_6764159_1 PFAM ABC transporter related K02003 - - 0.000000000001843 68.0
HFD2_k127_6766144_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 463.0
HFD2_k127_6768769_0 Zn peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000002758 241.0
HFD2_k127_6772031_0 O-Antigen ligase - - - 0.000000000000000003173 96.0
HFD2_k127_6772031_1 aspartic-type endopeptidase activity K02654 - 3.4.23.43 0.000000007842 66.0
HFD2_k127_6781929_0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 484.0
HFD2_k127_6781929_1 peroxiredoxin activity - - - 0.0000000000000000000000000000000000002474 147.0
HFD2_k127_6781929_2 Glycine reductase complex component B subunit gamma K10672 - 1.21.4.2 0.000000000000000000000000000000003035 134.0
HFD2_k127_6781929_3 In the first step of glycine, betaine and sarcosine reductases, the substrate is bound to component PB via a Schiff base intermediate. Then the PB-activated substrate is nucleophilically attacked by the selenol anion of component PA to transform it to a carboxymethylated selenoether and the respective amine. By action of component PC, acetyl phosphate is formed, leaving component PA in its oxidized state. Finally component PA becomes reduced by the thioredoxin system to start a new catalytic cycle of reductive deamination K10670 - 1.21.4.2,1.21.4.3,1.21.4.4 0.00000000000000000000005642 101.0
HFD2_k127_6781929_4 Glycine sarcosine betaine reductase complex K10670 - 1.21.4.2,1.21.4.3,1.21.4.4 0.00000001269 56.0
HFD2_k127_6783076_0 Cellulase (glycosyl hydrolase family 5) K05350 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009507 386.0
HFD2_k127_6783076_1 PFAM transposase, IS4 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000376 363.0
HFD2_k127_6785513_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 421.0
HFD2_k127_6785513_1 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000001835 74.0
HFD2_k127_67880_0 MFS_1 like family - - - 0.00000000000000000000000000000000000000000000000000001491 205.0
HFD2_k127_67880_1 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000002059 162.0
HFD2_k127_6798512_0 DDE superfamily endonuclease - - - 0.0000000000000000000000000000000000000000000000000000004661 196.0
HFD2_k127_682645_0 DEAD-like helicases superfamily K07012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002973 586.0
HFD2_k127_6828195_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002489 285.0
HFD2_k127_6828195_1 FAD binding domain - - - 0.000000000008457 69.0
HFD2_k127_6828195_2 FAD binding domain - - - 0.0000000006554 65.0
HFD2_k127_6828195_3 FAD binding domain - - - 0.000005702 51.0
HFD2_k127_6829594_0 ABC transporter K06147 GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006996,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009507,GO:0009526,GO:0009536,GO:0009555,GO:0009657,GO:0009658,GO:0009889,GO:0009941,GO:0009987,GO:0010035,GO:0010038,GO:0010288,GO:0010380,GO:0016020,GO:0016043,GO:0018130,GO:0019222,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0019866,GO:0022622,GO:0030003,GO:0031090,GO:0031323,GO:0031326,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0042221,GO:0042592,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0046686,GO:0046916,GO:0048229,GO:0048364,GO:0048731,GO:0048856,GO:0048878,GO:0050789,GO:0050790,GO:0050794,GO:0050801,GO:0050896,GO:0051171,GO:0051186,GO:0051188,GO:0051189,GO:0051193,GO:0051276,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0065009,GO:0071704,GO:0071840,GO:0090056,GO:0090407,GO:0098771,GO:0099402,GO:1901360,GO:1901362,GO:1901401,GO:1901463,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001263 278.0
HFD2_k127_683354_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710,K12450 GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 4.2.1.46,4.2.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 402.0
HFD2_k127_683354_1 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003653 306.0
HFD2_k127_683354_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 299.0
HFD2_k127_683354_3 TIGRFAM capsular exopolysaccharide family K08253 - 2.7.10.2 0.0000000000000000000000000000000000000000000000000006034 193.0
HFD2_k127_683354_4 PFAM lipopolysaccharide biosynthesis protein - - - 0.00000000001307 72.0
HFD2_k127_6834638_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 398.0
HFD2_k127_6834638_1 Mur ligase family, glutamate ligase domain K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008056 370.0
HFD2_k127_6834638_2 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000006849 227.0
HFD2_k127_6834638_3 Luciferase-like monooxygenase K14733 - 1.14.13.107 0.00000000000000000000000000000006064 128.0
HFD2_k127_6834638_4 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.0000000000000001495 81.0
HFD2_k127_6834638_5 Monooxygenase K14733 - 1.14.13.107 0.00000001123 64.0
HFD2_k127_6834638_6 Luciferase-like monooxygenase K14733 - 1.14.13.107 0.00073 44.0
HFD2_k127_6835207_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000002691 163.0
HFD2_k127_6835207_1 Glutathione peroxidase - - - 0.0000000000000000000000000000000000003627 146.0
HFD2_k127_6835207_2 Aminoacyl-tRNA editing domain K03976 - - 0.0000000000000000000000000001032 120.0
HFD2_k127_6836519_0 ABC transporter substrate binding protein K01989 - - 0.000000000000000000002193 104.0
HFD2_k127_6836519_1 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K01607 - 4.1.1.44 0.00000000000000000003223 91.0
HFD2_k127_6836519_2 cellulose binding - - - 0.000000007515 61.0
HFD2_k127_6836519_3 - - - - 0.00009515 50.0
HFD2_k127_6836519_4 - - - - 0.00009794 52.0
HFD2_k127_6845568_0 Nitrile hydratase, alpha chain K01721 - 4.2.1.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000002849 264.0
HFD2_k127_6845568_1 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000002645 258.0
HFD2_k127_6845568_2 Nitrile hydratase beta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006275 244.0
HFD2_k127_6845568_3 Chromate transporter K07240 - - 0.00000000000000000000000000000000003569 141.0
HFD2_k127_6845568_4 Pfam Chromate transporter K07240 - - 0.000000000000000000000000004772 120.0
HFD2_k127_6845568_5 Nitrile hydratase beta subunit - - - 0.00000000003788 67.0
HFD2_k127_6850665_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000002729 227.0
HFD2_k127_6850665_1 SnoaL-like domain - - - 0.0000000000000000000000007529 108.0
HFD2_k127_6850665_2 ethyl tert-butyl ether degradation - - - 0.0000000000000000001312 97.0
HFD2_k127_6850683_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0001101 54.0
HFD2_k127_6854864_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07306,K08352 - 1.8.5.3,1.8.5.5 2.099e-208 656.0
HFD2_k127_6854864_1 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000007836 68.0
HFD2_k127_6854864_2 Acetyltransferase (GNAT) domain - - - 0.00006465 48.0
HFD2_k127_6859797_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07306,K08352 - 1.8.5.3,1.8.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 610.0
HFD2_k127_6859797_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004915 271.0
HFD2_k127_6859797_2 MFS_1 like family - - - 0.0000000000000000000000000000000000000000000000000002754 203.0
HFD2_k127_6859797_3 - - - - 0.000000000000000000000000000000000001259 154.0
HFD2_k127_6863323_0 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000004703 217.0
HFD2_k127_6863323_1 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000004642 173.0
HFD2_k127_6870593_0 oligoendopeptidase F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001137 284.0
HFD2_k127_6870593_1 PFAM amidohydrolase 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000004456 235.0
HFD2_k127_6870593_2 Putative restriction endonuclease - - - 0.000000000000000000000000000000000000003845 152.0
HFD2_k127_6901802_0 Beta-lactamase superfamily domain K06897 - 2.5.1.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 316.0
HFD2_k127_6901802_1 Nitroreductase family - - - 0.00000000000000000000000000000000000000000607 160.0
HFD2_k127_6909557_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008512 582.0
HFD2_k127_6909557_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 334.0
HFD2_k127_6909557_2 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.00000000000000000000000000001092 121.0
HFD2_k127_6909902_0 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000006009 233.0
HFD2_k127_6909902_1 Rhodanese-like domain - - - 0.000000000000000000000000000003196 127.0
HFD2_k127_6923669_0 signal sequence binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008267 303.0
HFD2_k127_6923669_1 -transporter - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000001233 213.0
HFD2_k127_6923669_2 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000008325 70.0
HFD2_k127_6923669_3 Phosphotransferase K01007 - 2.7.9.2 0.0003504 43.0
HFD2_k127_6931225_0 Oxidoreductase K13327 - 1.1.1.384 0.000000000000000000000000000000000000000000000000000000003231 213.0
HFD2_k127_6931225_1 NDP-hexose 2,3-dehydratase - - - 0.00000000000000000000000000000000000000000000000000000002996 209.0
HFD2_k127_6931225_2 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000006409 161.0
HFD2_k127_6936222_0 PFAM glycosyl transferase, family 51 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002297 275.0
HFD2_k127_6936222_1 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.000000000000000000000000000000000004522 149.0
HFD2_k127_6940137_0 cyclopropane-fatty-acyl-phospholipid synthase K00574,K09846,K21192 - 2.1.1.210,2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000286 257.0
HFD2_k127_6940137_2 Flavin reductase like domain K00484 - 1.5.1.36 0.00000000000000000000000000000000000217 146.0
HFD2_k127_6940137_3 Transcriptional regulator - - - 0.00000000000000000000000000000000001372 146.0
HFD2_k127_6941152_0 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000008836 256.0
HFD2_k127_6941152_1 domain, Protein K09766 - - 0.000000000000001815 81.0
HFD2_k127_6953209_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 3.1e-231 754.0
HFD2_k127_6953209_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 500.0
HFD2_k127_6953209_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000001985 247.0
HFD2_k127_6953209_3 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000001211 239.0
HFD2_k127_6953209_4 PFAM YbbR family protein - - - 0.000000000000000000000000000000000000000000000000002962 197.0
HFD2_k127_6953209_5 - - - - 0.0000000000000000000000000000000000001372 148.0
HFD2_k127_6953209_6 amino acid activation for nonribosomal peptide biosynthetic process K05996 - 3.4.17.18 0.000000000000000000000000002153 128.0
HFD2_k127_6953209_7 phospholipid glycerol acyltransferase - - - 0.000000000000001132 86.0
HFD2_k127_6953209_8 Cytidylate kinase-like family - - - 0.000001381 54.0
HFD2_k127_6953209_9 Ribosomal protein S21 - - - 0.00003714 49.0
HFD2_k127_6996939_0 Bacterial Ig-like domain (group 3) - - - 0.0000000576 60.0
HFD2_k127_6997949_0 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006281 268.0
HFD2_k127_6997949_1 Single-stranded DNA-binding protein K03111 - - 0.0000000000000000000000000000179 126.0
HFD2_k127_6997949_2 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963,K03111,K15125 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000001973 120.0
HFD2_k127_6997949_3 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000007057 93.0
HFD2_k127_7006396_0 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 291.0
HFD2_k127_7006396_1 self proteolysis K01181,K02027,K17315,K17318 - 3.2.1.8 0.00000000000000000000000000000000000000000000000000000000000002081 236.0
HFD2_k127_7013402_0 Glycosyl transferase 4-like - - - 0.00000000000000000000000005716 121.0
HFD2_k127_7013402_1 transcriptional regulator K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.000004756 56.0
HFD2_k127_7021234_0 Belongs to the Nudix hydrolase family - - - 0.0000000000000000001132 96.0
HFD2_k127_7021234_1 DUF218 domain - - - 0.0000000000000114 82.0
HFD2_k127_7021234_2 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.00000000000005618 78.0
HFD2_k127_7024605_0 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000001549 232.0
HFD2_k127_7024605_1 protein homooligomerization - - - 0.0000000000000000000000000000000000000000000000000000003727 207.0
HFD2_k127_7024605_2 chlorophyll binding - - - 0.00000000000000000000000000000000006789 143.0
HFD2_k127_7024605_3 Uncharacterized protein conserved in bacteria (DUF2169) - - - 0.00007875 48.0
HFD2_k127_7031728_0 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000828 491.0
HFD2_k127_7031728_1 CoA-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 356.0
HFD2_k127_7031728_2 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000009758 271.0
HFD2_k127_7039071_0 Succinyl-CoA ligase like flavodoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 434.0
HFD2_k127_7039071_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000009324 200.0
HFD2_k127_7039071_2 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.000000000000000000838 95.0
HFD2_k127_7040981_0 Glycosyl hydrolase family 76 - - - 0.000000000000000000000000000000000000000001251 169.0
HFD2_k127_7040981_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000004011 163.0
HFD2_k127_704290_0 Acyl-CoA dehydrogenase K00252 - 1.3.8.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 476.0
HFD2_k127_704290_1 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000000000005674 168.0
HFD2_k127_704290_2 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00000000000000000000000001846 110.0
HFD2_k127_704572_0 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000004039 246.0
HFD2_k127_704572_1 Domain of unknown function (DUF4870) - - - 0.0000000000000000002224 93.0
HFD2_k127_7047303_0 Major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000002524 244.0
HFD2_k127_7047303_1 Appr-1'-p processing enzyme - - - 0.00000000000000000000000000000000000000000000000000000002385 203.0
HFD2_k127_7047303_2 ABC-type antimicrobial peptide transport system, permease component - - - 0.00000001682 66.0
HFD2_k127_7049070_0 PFAM Mur ligase, middle domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 439.0
HFD2_k127_7049070_1 PFAM CobB CobQ domain protein glutamine amidotransferase K07009 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003941 283.0
HFD2_k127_7049070_2 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.000000000000000000000000000000000000000000000000000000002574 209.0
HFD2_k127_7049070_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000008626 108.0
HFD2_k127_7054223_0 helix_turn_helix, Lux Regulon K03556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005881 311.0
HFD2_k127_7055108_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 349.0
HFD2_k127_7055108_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008829 323.0
HFD2_k127_7055108_2 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000177 223.0
HFD2_k127_7055108_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409,K03070 GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.0000000000000000000000000000000000000000000008135 169.0
HFD2_k127_7061740_0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00042 - 1.1.1.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 361.0
HFD2_k127_7061740_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004683 324.0
HFD2_k127_7061740_2 GHKL domain K07641 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000008071 219.0
HFD2_k127_7061740_3 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.0000000000000000000000000000000000000000000000000000003749 201.0
HFD2_k127_7061740_4 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000437 202.0
HFD2_k127_7061740_5 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.00000000000000000000000002037 114.0
HFD2_k127_7061740_6 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000001765 61.0
HFD2_k127_7066084_0 ECF sigma factor K03088 - - 0.00000000000000000003891 97.0
HFD2_k127_7066084_1 Belongs to the sigma-70 factor family K03088 - - 0.0000000001753 64.0
HFD2_k127_7067343_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007961 308.0
HFD2_k127_7067343_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.00000000000000000000000000000000000000007724 156.0
HFD2_k127_7067343_2 Uracil DNA glycosylase superfamily - - - 0.00000000000000000000000002241 118.0
HFD2_k127_7067343_3 D-alanyl-D-alanine carboxypeptidase K07260 - 3.4.17.14 0.00000000000000000000009608 110.0
HFD2_k127_7085607_0 Predicted membrane protein (DUF2254) - - - 0.000000000000000000000000000000000000000000000000000057 205.0
HFD2_k127_7085607_1 Methyltransferase domain K07003 - - 0.00000000000000000000000002926 119.0
HFD2_k127_7085607_2 Isochorismatase family K13995 - 3.5.1.107 0.000000000000000006821 92.0
HFD2_k127_7088797_0 TIGRFAM amino acid adenylation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006317 507.0
HFD2_k127_7088797_1 Pfam:HxxPF_rpt - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 353.0
HFD2_k127_7088797_2 Linear gramicidin synthase subunit - - - 0.0000000000000000000000000000000000002251 144.0
HFD2_k127_7098530_0 KR domain K10780 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003326 299.0
HFD2_k127_7098530_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000002792 72.0
HFD2_k127_7098530_2 response regulator, receiver - - - 0.000000009471 64.0
HFD2_k127_7109942_0 Aminopeptidase K01256,K08776 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.11.2 4.862e-218 706.0
HFD2_k127_7109942_1 iron-sulfur cluster assembly K07400,K13628 - - 0.000000000000000000000000000000000000000000000000009574 189.0
HFD2_k127_7109942_2 ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp - - - 0.00000000000000000000000000004257 119.0
HFD2_k127_7110764_0 MgsA AAA+ ATPase C terminal K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006221 325.0
HFD2_k127_7110764_1 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003925 280.0
HFD2_k127_7110764_2 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.000132 48.0
HFD2_k127_7112841_0 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 443.0
HFD2_k127_7112841_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000005821 203.0
HFD2_k127_7112841_2 Protein of unknown function (DUF433) - - - 0.00000001221 61.0
HFD2_k127_7119986_0 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 352.0
HFD2_k127_7119986_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 312.0
HFD2_k127_7119986_2 Protein of unknown function (DUF1800) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 306.0
HFD2_k127_7119986_3 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009383 271.0
HFD2_k127_7119986_4 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001145 265.0
HFD2_k127_7119986_5 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000002768 188.0
HFD2_k127_7124087_0 Belongs to the glycosyl hydrolase 26 family - - - 0.00000000000000000000000000000000000000000000000001168 188.0
HFD2_k127_7124087_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000006196 180.0
HFD2_k127_7124087_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000634 82.0
HFD2_k127_7130085_0 56kDa selenium binding protein (SBP56) K17285 - - 1.117e-245 764.0
HFD2_k127_7130085_1 AAA ATPase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004996 519.0
HFD2_k127_7130085_2 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 412.0
HFD2_k127_7130085_3 Mo-molybdopterin cofactor metabolic process K03636 - - 0.0000000000000000000000000000000000000000000000000000000000000000007266 238.0
HFD2_k127_7130085_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000004681 221.0
HFD2_k127_7130085_5 integral membrane protein (DUF2270) - - - 0.000000000000000000000000000000000000000000000000000000000222 209.0
HFD2_k127_7130085_6 Belongs to the LDH2 MDH2 oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000001264 199.0
HFD2_k127_7130085_7 MFS_1 like family - - - 0.000000000000000000000000000000000000000000000004992 192.0
HFD2_k127_7130085_8 PFAM LmbE family protein - - - 0.00000000000000000000000000000000000000000000001352 181.0
HFD2_k127_7130085_9 Major Facilitator Superfamily - - - 0.0000000000000000000000000002173 130.0
HFD2_k127_7153451_0 PFAM glycoside hydrolase family 39 - - - 0.000000000000000000000000000000000000000001454 170.0
HFD2_k127_7153451_1 Belongs to the 'phage' integrase family - - - 0.0000003456 54.0
HFD2_k127_7155752_0 arginyl-tRNA aminoacylation K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 551.0
HFD2_k127_7155752_1 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008634 255.0
HFD2_k127_7155752_2 ABC transporter K01996 - - 0.00000000000000000000000000000000001143 139.0
HFD2_k127_7165728_0 Pfam:HxxPF_rpt - - - 3.519e-234 745.0
HFD2_k127_7183149_0 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000002911 174.0
HFD2_k127_7183149_1 Predicted membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000008582 148.0
HFD2_k127_7183149_2 PFAM phosphate transporter K03306 - - 0.000000000000000000001051 96.0
HFD2_k127_7183149_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000001055 100.0
HFD2_k127_7184025_0 Peptidase family M41 - - - 0.000000000000000000000000000000000000000008159 158.0
HFD2_k127_7184025_1 COG0001 Glutamate-1-semialdehyde aminotransferase K01845 - 5.4.3.8 0.0000000000000000000000000000000000003102 143.0
HFD2_k127_7184025_2 - - - - 0.000005224 55.0
HFD2_k127_7189359_0 ligase activity, forming carbon-carbon bonds K07402 - - 0.0000000000000000000000000000000000000000000000000007014 202.0
HFD2_k127_7189359_1 Sugar (and other) transporter - - - 0.00002049 55.0
HFD2_k127_7196641_0 Potential Queuosine, Q, salvage protein family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009402 329.0
HFD2_k127_7196641_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000001563 142.0
HFD2_k127_7196641_2 Uncharacterized conserved protein (COG2071) K09166 - - 0.000000000000000000000001578 105.0
HFD2_k127_720101_0 PFAM PDZ DHR GLGF domain protein K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005746 317.0
HFD2_k127_720101_1 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070930,GO:0071704,GO:1901564 - 0.00000000000000000000006871 99.0
HFD2_k127_7204221_0 HTH-like domain K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 310.0
HFD2_k127_7204221_1 FCD K05799 - - 0.00000000000000000000000000000000000000000000000002256 190.0
HFD2_k127_7204221_2 PFAM transposase IS3 IS911 family protein K07483 - - 0.0000000000000000000000000001202 117.0
HFD2_k127_7204221_3 PFAM Integrase catalytic region K07497 - - 0.0000000000000001439 89.0
HFD2_k127_7212287_0 glutamate synthase K00266 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 7.568e-238 742.0
HFD2_k127_7212287_1 Conserved region in glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 296.0
HFD2_k127_7218287_0 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000099 338.0
HFD2_k127_7218287_1 MmgE/PrpD family - - - 0.000000000000000000000000000000004107 133.0
HFD2_k127_7218287_2 PFAM PemK-like protein K07171 - - 0.00000000000000000000000728 104.0
HFD2_k127_7218287_3 - - - - 0.00001088 55.0
HFD2_k127_7220165_0 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004133 422.0
HFD2_k127_7233806_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 422.0
HFD2_k127_7233806_1 Lactonase, 7-bladed beta-propeller K07404 - 3.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009289 412.0
HFD2_k127_7233806_2 succinyl-diaminopimelate desuccinylase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 297.0
HFD2_k127_7233806_3 C-terminal four TMM region of protein-O-mannosyltransferase K00728 - 2.4.1.109 0.000002015 55.0
HFD2_k127_7235408_0 ATP-dependent peptidase activity K01338 - 3.4.21.53 1.153e-223 712.0
HFD2_k127_7235408_1 PFAM Heat shock protein Hsp20 K13993 - - 0.000000000000000001097 92.0
HFD2_k127_7240995_0 PFAM Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000006925 212.0
HFD2_k127_7240995_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.0000000000000000000000000000000000000000000000000000002838 197.0
HFD2_k127_7240995_2 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.000000000000000000000000000000000000000000005655 171.0
HFD2_k127_7240995_3 HAD-hyrolase-like - - - 0.0000000000000000000000000000000000000000000328 174.0
HFD2_k127_7240995_4 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K03921 - 1.14.19.11,1.14.19.2,1.14.19.26 0.00000000000000000000000000000000000000006105 163.0
HFD2_k127_7240995_5 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000006106 112.0
HFD2_k127_7242652_0 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009122 295.0
HFD2_k127_7242652_1 Protein of unknown function (DUF1003) - - - 0.00000000000000000000000000000000006281 142.0
HFD2_k127_7242652_2 F420H(2)-dependent quinone reductase - - - 0.000000000000000000000000000000002358 132.0
HFD2_k127_7252898_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000761 167.0
HFD2_k127_7261183_0 CoA enzyme activase uncharacterised domain (DUF2229) - - - 2.226e-303 959.0
HFD2_k127_7261183_1 BadF BadG BcrA BcrD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 313.0
HFD2_k127_7261183_10 Beta-galactosidase - - - 0.0000000000000000002194 96.0
HFD2_k127_7261183_11 Regulatory protein, FmdB family - - - 0.000002522 55.0
HFD2_k127_7261183_2 Belongs to the bacterial solute-binding protein 9 family K09815,K09818 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002427 252.0
HFD2_k127_7261183_3 ABC-type Mn2 Zn2 transport system, permease component K09816,K09819,K19976 - - 0.0000000000000000000000000000000000000000000000000000000000001674 223.0
HFD2_k127_7261183_4 ATPases associated with a variety of cellular activities K02074,K09820,K11710,K19973 - 3.6.3.35 0.0000000000000000000000000000000000000000000001959 183.0
HFD2_k127_7261183_5 Lysin motif - - - 0.000000000000000000000000000000000966 144.0
HFD2_k127_7261183_6 PFAM Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000000000000000000002053 132.0
HFD2_k127_7261183_7 Zn peptidase - - - 0.0000000000000000000000000001778 132.0
HFD2_k127_7261183_8 Methyltransferase domain - - - 0.000000000000000000000000002472 121.0
HFD2_k127_7261183_9 Ferric uptake regulator family K03711 - - 0.000000000000000000000000002647 117.0
HFD2_k127_727269_0 PFAM Serine threonine protein kinase-related K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000969 202.0
HFD2_k127_7274198_0 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K04091 - 1.14.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 469.0
HFD2_k127_7274198_1 Polymer-forming cytoskeletal - - - 0.0000000000000000000000002268 119.0
HFD2_k127_7278754_0 Winged helix DNA-binding domain K09927 - - 0.00000000000000000000000000000000000004177 149.0
HFD2_k127_7278754_1 Winged helix DNA-binding domain K09927 - - 0.0001335 49.0
HFD2_k127_7279405_0 PFAM Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000505 236.0
HFD2_k127_7279405_1 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.0000000000004453 79.0
HFD2_k127_728208_0 Adenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000003922 200.0
HFD2_k127_728208_1 Belongs to the CinA family - - - 0.00000000000000000000000000000000000000000000000006125 183.0
HFD2_k127_7284124_0 Belongs to the TPP enzyme family K01576 - 4.1.1.7 0.0000000000000000000000000000000000000000000000003701 183.0
HFD2_k127_7290489_0 Acyl-CoA reductase (LuxC) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007493 381.0
HFD2_k127_7290489_1 PFAM ABC transporter related K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001334 270.0
HFD2_k127_7290489_2 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000001226 235.0
HFD2_k127_7292172_0 Hydantoinase B/oxoprolinase - - - 0.000000000000000000000000000000000000000001806 161.0
HFD2_k127_7292172_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000004132 64.0
HFD2_k127_7300705_0 3-carboxyethylcatechol 2,3-dioxygenase activity K05713 - 1.13.11.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008384 310.0
HFD2_k127_7300705_1 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002393 257.0
HFD2_k127_7300705_2 extracellular solute-binding protein, family 7 K11688 - - 0.000000000000000000000000000000000000000007731 169.0
HFD2_k127_7308607_0 Binding-protein-dependent transport system inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002403 255.0
HFD2_k127_7308607_1 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000001847 239.0
HFD2_k127_7308607_2 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol - - - 0.0001859 46.0
HFD2_k127_7308607_3 Extracellular solute-binding protein - - - 0.0008102 52.0
HFD2_k127_7320838_0 Domain of unknown function (DUF4157) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 310.0
HFD2_k127_7326804_0 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 281.0
HFD2_k127_7326804_1 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007712 284.0
HFD2_k127_7326804_2 Mur ligase family, glutamate ligase domain K11754 - 6.3.2.12,6.3.2.17 0.00002032 48.0
HFD2_k127_7330297_0 Peptidase inhibitor I9 K20754 - 3.4.21.111 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 412.0
HFD2_k127_7363489_0 PFAM GMC oxidoreductase - - - 1.139e-204 649.0
HFD2_k127_7367674_0 Tricorn protease homolog K08676 - - 0.0 1287.0
HFD2_k127_7373853_0 MFS_1 like family K08161 - - 0.0000000000000000000000000000000000000000000000004622 192.0
HFD2_k127_7373957_0 ABC-type multidrug transport system ATPase and permease K18890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009861 574.0
HFD2_k127_7373957_1 ABC-type multidrug transport system ATPase and permease K18889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003058 258.0
HFD2_k127_7381642_0 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002003 264.0
HFD2_k127_7381642_1 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000003433 166.0
HFD2_k127_7386680_0 Putative serine dehydratase domain K18425 - 4.1.3.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 378.0
HFD2_k127_7386680_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003377 283.0
HFD2_k127_7386680_2 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000009193 224.0
HFD2_k127_7386680_3 Maleate cis-trans isomerase K01799 - 5.2.1.1 0.0000000000000000000000000000000000000000000000000000000000003254 220.0
HFD2_k127_7386680_4 transcriptional regulator - - - 0.00000000001173 78.0
HFD2_k127_7386680_5 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000001316 55.0
HFD2_k127_7394243_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000001091 178.0
HFD2_k127_7404842_0 Protein of unknown function (DUF3891) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 289.0
HFD2_k127_7404842_1 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000002554 199.0
HFD2_k127_7408761_0 Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 488.0
HFD2_k127_7414812_0 iron dependent repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002937 256.0
HFD2_k127_7414812_1 DDE superfamily endonuclease - - - 0.000000000000000000000000000000000000001258 156.0
HFD2_k127_7414812_2 Transposase - - - 0.00000000000000000000000000000000129 136.0
HFD2_k127_7414812_3 Transposase - - - 0.00000000013 63.0
HFD2_k127_7416023_0 PFAM amidohydrolase 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 332.0
HFD2_k127_7416023_1 phosphogluconate dehydrogenase (decarboxylating) activity K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001241 275.0
HFD2_k127_7416023_2 PFAM Tetratricopeptide TPR_4 - - - 0.000000000000009071 79.0
HFD2_k127_741911_0 thiosulfate sulfurtransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 337.0
HFD2_k127_741911_1 - - - - 0.000000000008448 66.0
HFD2_k127_7424352_0 Domain of unknown function (DUF4157) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 451.0
HFD2_k127_7441338_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005895 300.0
HFD2_k127_7441338_1 Circularly permuted ATP-grasp type 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002232 267.0
HFD2_k127_7441338_2 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001704 267.0
HFD2_k127_7441338_3 Endoribonuclease L-PSP - - - 0.0000000000000000000000000003484 117.0
HFD2_k127_7441338_4 SPTR Q2LSA8 Transposase and inactivated derivatives - - - 0.0000000000000000000000003035 112.0
HFD2_k127_7441338_5 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K01652 - 2.2.1.6 0.000000000000002767 77.0
HFD2_k127_7441338_6 Homeodomain-like domain - - - 0.0001151 53.0
HFD2_k127_7441338_7 DDE superfamily endonuclease - - - 0.0008731 44.0
HFD2_k127_7441338_8 Homeodomain-like domain - - - 0.000945 43.0
HFD2_k127_7441479_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006478 509.0
HFD2_k127_7441479_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000001146 157.0
HFD2_k127_7465934_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006378 529.0
HFD2_k127_7465934_1 Trehalose utilisation K09992 - - 0.00000000000000000002488 97.0
HFD2_k127_7471803_0 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 409.0
HFD2_k127_7471803_1 Inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000106 173.0
HFD2_k127_7471803_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K00320 - 1.5.98.2 0.00000000000000000000000000000008008 138.0
HFD2_k127_748253_0 helix_turn_helix, Lux Regulon K03556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005709 501.0
HFD2_k127_7503681_0 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1055.0
HFD2_k127_7503681_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.417e-202 646.0
HFD2_k127_7503681_10 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000002468 121.0
HFD2_k127_7503681_11 tetraacyldisaccharide 4'-kinase activity K09791 - - 0.0000000000000004694 87.0
HFD2_k127_7503681_12 Lysylphosphatidylglycerol synthase TM region K07027,K20468 - - 0.000000000002739 78.0
HFD2_k127_7503681_13 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000001195 56.0
HFD2_k127_7503681_14 PFAM O-Antigen - - - 0.00000004031 67.0
HFD2_k127_7503681_15 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000001775 61.0
HFD2_k127_7503681_2 4Fe-4S ferredoxin iron-sulfur binding domain protein K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005314 390.0
HFD2_k127_7503681_3 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003649 291.0
HFD2_k127_7503681_4 calcium, potassium:sodium antiporter activity K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006789 267.0
HFD2_k127_7503681_5 - K00241 - - 0.00000000000000000000000000000000000000000000000000000000000000005875 229.0
HFD2_k127_7503681_6 Integral membrane protein TerC family - - - 0.00000000000000000000000000000000000000000008223 168.0
HFD2_k127_7503681_7 4-amino-4-deoxy-L-arabinose transferase activity K00728 - 2.4.1.109 0.000000000000000000000000000000000000009789 166.0
HFD2_k127_7503681_8 4-amino-4-deoxy-L-arabinose transferase activity K00728 - 2.4.1.109 0.0000000000000000000000000000000000005247 158.0
HFD2_k127_7503681_9 4-amino-4-deoxy-L-arabinose transferase activity K00728 - 2.4.1.109 0.0000000000000000000000000000001587 143.0
HFD2_k127_7511167_0 ABC-type Fe3 transport system permease component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006018 407.0
HFD2_k127_7511167_1 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000002452 109.0
HFD2_k127_7536511_0 4fe-4S ferredoxin, iron-sulfur binding domain protein K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 479.0
HFD2_k127_7536511_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000001346 80.0
HFD2_k127_7536511_2 FAD binding domain K11472 - - 0.00000000006239 63.0
HFD2_k127_7539949_0 metallopeptidase activity K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003796 360.0
HFD2_k127_7539949_1 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.00000000000000000000000000000008123 128.0
HFD2_k127_7539949_2 Modulator of DNA gyrase K03592 - - 0.000000000000005676 83.0
HFD2_k127_7540493_0 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000478 422.0
HFD2_k127_7540493_1 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002465 329.0
HFD2_k127_7540493_2 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000002999 227.0
HFD2_k127_7540493_3 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00015 - 1.1.1.26 0.0000179 51.0
HFD2_k127_7540500_0 Mur ligase middle domain K11754 GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000002001 223.0
HFD2_k127_7545339_0 CHAT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 351.0
HFD2_k127_7545339_1 belongs to the sigma-70 factor family, ECF subfamily - - - 0.000000000000000000000000000001272 128.0
HFD2_k127_7545339_2 3-demethylubiquinone-9 3-O-methyltransferase activity K00568,K18827 - 2.1.1.222,2.1.1.294,2.1.1.64,2.7.1.181 0.00000000000001519 83.0
HFD2_k127_7545916_0 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000001062 192.0
HFD2_k127_7545916_1 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000001451 171.0
HFD2_k127_7545916_2 Galactose oxidase, central domain - - - 0.0000000000000000000000000000000000000000007689 172.0
HFD2_k127_7545916_3 - - - - 0.000000000000000000000001805 106.0
HFD2_k127_7545916_4 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000006753 74.0
HFD2_k127_7546385_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 592.0
HFD2_k127_7546385_1 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002569 297.0
HFD2_k127_7547524_0 Involved in the catabolism of oxalate and in the adapatation to low pH. ACOCT serves to prime the oxalate-induced acid tolerance response (ATR) cycle by producing substrate for oxalyl-CoA decarboxylase (OXC) and formyl-coenzyme A transferase (FCOCT). Catalyzes the reversible conversion of acetyl-CoA and oxalate to oxalyl-CoA and acetate. It can also use formyl-CoA and oxalate to produce oxalyl-CoA and formate with significantly reduced specific activity K18702 GO:0003674,GO:0003824,GO:0008410,GO:0016740,GO:0016782,GO:0036412 2.8.3.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 301.0
HFD2_k127_7547524_1 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000005349 243.0
HFD2_k127_7548294_0 Belongs to the aldehyde dehydrogenase family K22187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 486.0
HFD2_k127_7548294_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000002963 214.0
HFD2_k127_7548294_2 regulator of chromosome condensation, RCC1 - - - 0.000000000000000000000000000000000000001745 153.0
HFD2_k127_7548294_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000002132 133.0
HFD2_k127_7548294_4 Ribosomal protein L9, N-terminal domain K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000003531 131.0
HFD2_k127_7548294_5 - - - - 0.000000000000000000001656 105.0
HFD2_k127_7553253_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007155 417.0
HFD2_k127_7553253_1 probably involved in cell wall biogenesis K00694 - 2.4.1.12 0.000000000000000000000000000000000000000000000000000000000000000000005902 258.0
HFD2_k127_7555168_0 PFAM Glucose Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004123 374.0
HFD2_k127_7555168_1 amino acid activation for nonribosomal peptide biosynthetic process K05996 - 3.4.17.18 0.0000000000000000000000000000000129 144.0
HFD2_k127_7555168_2 Glycosyltransferases involved in cell wall biogenesis-like protein - - - 0.0000000000000319 85.0
HFD2_k127_7557852_0 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006776 289.0
HFD2_k127_7557852_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004946 258.0
HFD2_k127_7557852_2 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000009226 143.0
HFD2_k127_758600_0 Ethanolamine utilization protein EutJ K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006639 284.0
HFD2_k127_758600_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000976 256.0
HFD2_k127_758600_2 Belongs to the binding-protein-dependent transport system permease family K01995 - - 0.00000000000000000000000000000000000000000000000000711 200.0
HFD2_k127_758600_3 - - - - 0.000000007917 63.0
HFD2_k127_7586649_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 574.0
HFD2_k127_7586649_1 Linear amide C-N hydrolases, choloylglycine hydrolase family K01442 - 3.5.1.24 0.0000000000000000000000000000000000000001859 166.0
HFD2_k127_7586649_2 to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000339 65.0
HFD2_k127_7586649_3 PHP domain protein - - - 0.0000000005742 69.0
HFD2_k127_7586649_4 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859,K07566 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24,2.7.7.87 0.00000003876 55.0
HFD2_k127_7594748_0 Fumarate reductase flavoprotein C-term K00239,K00244 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005495 367.0
HFD2_k127_7594748_1 PFAM NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 347.0
HFD2_k127_7594748_10 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K07755 - 2.1.1.137 0.00000000000005958 74.0
HFD2_k127_7594748_11 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K07755 - 2.1.1.137 0.00000000001219 72.0
HFD2_k127_7594748_12 - - - - 0.000002831 53.0
HFD2_k127_7594748_2 Xanthine uracil vitamin C permease K06901 - - 0.0000000000000000000000000000000000001952 146.0
HFD2_k127_7594748_3 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.0000000000000000000000000000000000009987 142.0
HFD2_k127_7594748_4 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000000000000000004553 135.0
HFD2_k127_7594748_5 Belongs to the 'phage' integrase family K03733,K04763 - - 0.00000000000000000000000004594 117.0
HFD2_k127_7594748_6 Methyltransferase K07755 - 2.1.1.137 0.00000000000000000002074 91.0
HFD2_k127_7594748_7 Toxic component of a toxin-antitoxin (TA) module. An RNase K07062 - - 0.000000000000000001156 90.0
HFD2_k127_7594748_9 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.0000000000000001299 83.0
HFD2_k127_7600278_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 345.0
HFD2_k127_760523_0 Putative cyclase - - - 0.0000000000000000000000000000269 126.0
HFD2_k127_760523_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.00000000000000000000000000005187 126.0
HFD2_k127_760523_2 Alpha/beta hydrolase family - - - 0.00000000000000000000000005235 112.0
HFD2_k127_760523_3 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.0000000000000000000000006196 114.0
HFD2_k127_761448_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004411 432.0
HFD2_k127_761448_1 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005915 314.0
HFD2_k127_761448_2 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000201 190.0
HFD2_k127_7615674_0 transferase activity, transferring glycosyl groups K01365,K14475 - 3.4.22.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 428.0
HFD2_k127_7615674_1 Associated with various cellular activities K03924 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003001 260.0
HFD2_k127_7615674_2 ATPase activity K01990 - - 0.000000000000000000000000000000000000000000000000000000000006396 221.0
HFD2_k127_7615674_3 cellulose binding - - - 0.00000000000000000000000000000000000000000001618 175.0
HFD2_k127_7615674_4 PFAM AMP-dependent synthetase and ligase - - - 0.00000000000000000000000000000000000000000009816 183.0
HFD2_k127_7615674_5 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000009035 162.0
HFD2_k127_7615674_6 - - - - 0.00000000000000000000001632 105.0
HFD2_k127_7615674_7 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000001261 102.0
HFD2_k127_7615674_8 translation initiation factor activity - - - 0.0000000000000000008766 100.0
HFD2_k127_7615674_9 PFAM ABC-2 type transporter - - - 0.0003177 52.0
HFD2_k127_762313_0 Glycosyl hydrolase family 36 N-terminal domain K07407 - 3.2.1.22 0.000000000000000000000009992 116.0
HFD2_k127_7623376_0 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817,K04720 - 2.6.1.9,4.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004905 306.0
HFD2_k127_7623376_1 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005958 263.0
HFD2_k127_7623376_2 Uncharacterised ArCR, COG2043 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002029 260.0
HFD2_k127_7623376_3 Phosphoesterase family K01114 - 3.1.4.3 0.000000000000000000000000000000000000000000000000000000000000006112 235.0
HFD2_k127_7623376_4 Glycyl-tRNA synthetase, alpha subunit K01878,K14164 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016874,GO:0016875,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 0.0000000000000000000000000000000000000000006232 158.0
HFD2_k127_7623376_5 Domain of unknown function (DUF309) K09763 - - 0.000000000000000000000000000008777 123.0
HFD2_k127_7623376_6 repeat protein - - - 0.0000000012 70.0
HFD2_k127_7624254_0 Amidohydrolase family K01485 - 3.5.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009397 377.0
HFD2_k127_7624254_1 Formiminotransferase-cyclodeaminase K00603,K01746,K13990 - 2.1.2.5,4.3.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001042 274.0
HFD2_k127_7624254_2 Tetrapyrrole (Corrin/Porphyrin) Methylases K13541 - 2.1.1.131,3.7.1.12 0.0000000000000000000000000000000000000000000000000000000000000000009215 237.0
HFD2_k127_7624254_3 Formiminotransferase-cyclodeaminase K13990 - 2.1.2.5,4.3.1.4 0.00000000000000000000000000000003014 134.0
HFD2_k127_7624254_5 Aminotransferase K00817,K04720 GO:0008150,GO:0040007 2.6.1.9,4.1.1.81 0.0009165 42.0
HFD2_k127_7640369_0 Spermidine synthase tetramerisation domain K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000271 201.0
HFD2_k127_7640369_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000001222 157.0
HFD2_k127_7640369_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000002307 100.0
HFD2_k127_7640369_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000005003 63.0
HFD2_k127_7644309_0 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 6.3.4.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 360.0
HFD2_k127_7644309_1 PFAM Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000003144 241.0
HFD2_k127_7644309_2 Ion channel K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000001061 240.0
HFD2_k127_7644309_3 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 GO:0008150,GO:0040007 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000004727 209.0
HFD2_k127_7644309_5 Thioesterase superfamily K07107 - - 0.00000000000000001736 89.0
HFD2_k127_7644309_6 PFAM O-antigen polymerase - - - 0.0000000000001878 80.0
HFD2_k127_7657354_0 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008879 284.0
HFD2_k127_7657354_1 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003363 288.0
HFD2_k127_7657354_2 PFAM glycosyl transferase family 2 K07011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006584 279.0
HFD2_k127_7657354_3 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000008307 230.0
HFD2_k127_7657354_4 PFAM glycosyl transferase family 2 K07011 - - 0.000000000000000000000000000000000000000000000000000000000709 213.0
HFD2_k127_7657354_5 signal transduction histidine kinase - - - 0.00000000000000000000000000004932 131.0
HFD2_k127_7665042_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 329.0
HFD2_k127_7665042_1 Protein of unknown function (DUF420) K08976 - - 0.00000000000000000000000000000000000000000008081 163.0
HFD2_k127_7665042_2 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000001656 132.0
HFD2_k127_7671568_0 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 334.0
HFD2_k127_7671568_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009305 319.0
HFD2_k127_7671568_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000941 305.0
HFD2_k127_7671568_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000009161 170.0
HFD2_k127_7671568_4 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.0000000000000000000000000000000008745 138.0
HFD2_k127_7671568_5 [2Fe-2S] binding domain - - - 0.000000000000000000002938 94.0
HFD2_k127_7675837_0 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 542.0
HFD2_k127_7675837_1 Belongs to the glycosyl hydrolase 57 family - - - 0.00001242 49.0
HFD2_k127_7677184_0 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 323.0
HFD2_k127_7677184_1 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000163 294.0
HFD2_k127_7677184_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005951 249.0
HFD2_k127_7677184_3 YceI-like domain - - - 0.0000000000000000000000000000000000000000000000002055 184.0
HFD2_k127_768319_0 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 516.0
HFD2_k127_768319_1 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 466.0
HFD2_k127_768319_2 oxidoreductase beta subunit K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007546 350.0
HFD2_k127_768319_3 FeS assembly protein SufD K07033,K09015 GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0040007,GO:0043207,GO:0044085,GO:0044237,GO:0044403,GO:0044419,GO:0050896,GO:0051186,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071840,GO:0075136 - 0.000000000000000000000000000000000000000000000000007854 193.0
HFD2_k127_768319_4 NifU-like N terminal domain K04488 - - 0.000000000000000000000000000000000000006211 150.0
HFD2_k127_768319_5 Pfam:DUF59 K02612 - - 0.000000000000000000000000292 109.0
HFD2_k127_768319_6 Rieske-like [2Fe-2S] domain K05710 - - 0.000000000000000000005288 104.0
HFD2_k127_768319_7 PFAM Dual specificity protein phosphatase - - - 0.00000001981 60.0
HFD2_k127_7687558_0 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007285 515.0
HFD2_k127_7687558_1 PFAM AIR synthase related protein K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001172 288.0
HFD2_k127_7687558_2 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000003837 188.0
HFD2_k127_7687558_3 Haloacid dehalogenase domain protein hydrolase K07025 - - 0.0000000000000000000000002256 115.0
HFD2_k127_7687558_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000006182 105.0
HFD2_k127_7691487_0 PFAM WD domain, G-beta repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 423.0
HFD2_k127_7691487_1 TIR domain - - - 0.00000000000000000000000000000000000000002286 158.0
HFD2_k127_7696819_0 GAF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009854 463.0
HFD2_k127_7700818_0 aconitate hydratase - - - 0.0 1077.0
HFD2_k127_7700818_1 NADH:flavin oxidoreductase / NADH oxidase family - - - 2.133e-218 693.0
HFD2_k127_7700818_2 epimerase - - - 0.000000000000000000000000000000000000000000000005321 179.0
HFD2_k127_7712660_0 SMART helicase c2 K03722 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000001443 213.0
HFD2_k127_7712660_1 ECF sigma factor K03088 - - 0.000000000000000000000000000001365 129.0
HFD2_k127_7715574_0 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003001 289.0
HFD2_k127_7715574_1 PFAM NHL repeat containing protein - - - 0.000000000000000000000000000000000000000000000002732 186.0
HFD2_k127_7715574_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000009532 86.0
HFD2_k127_7717106_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 480.0
HFD2_k127_7717106_1 FAD dependent oxidoreductase K00285,K03153 - 1.4.3.19,1.4.5.1 0.000000000000000000000000000000000000000005307 164.0
HFD2_k127_7724340_0 ABC-3 protein K09816,K09819 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005553 302.0
HFD2_k127_7724340_1 AAA domain, putative AbiEii toxin, Type IV TA system K02074,K09817,K11607,K11710 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001226 283.0
HFD2_k127_7724340_2 Belongs to the bacterial solute-binding protein 9 family K09818 - - 0.00000000000000034 81.0
HFD2_k127_7752310_0 Major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 375.0
HFD2_k127_7752310_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 362.0
HFD2_k127_7752310_2 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000000000007423 89.0
HFD2_k127_7753404_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005733 452.0
HFD2_k127_7753404_1 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000001018 238.0
HFD2_k127_7753404_2 Carboxymuconolactone decarboxylase K01607 - 4.1.1.44 0.00000000000000000000006681 109.0
HFD2_k127_77536_0 Belongs to the LDH2 MDH2 oxidoreductase family K00073,K13574 - 1.1.1.350 0.000000000000000000000000000000000000000000000000000000000000002974 230.0
HFD2_k127_77536_1 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000001368 154.0
HFD2_k127_7767981_0 PFAM SMP-30 Gluconolaconase LRE domain protein K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 286.0
HFD2_k127_7767981_1 Gluconolactonase K01053,K14274 - 3.1.1.17 0.0000004287 53.0
HFD2_k127_7773956_0 - - - - 0.00000000000000000000000000000000000001238 146.0
HFD2_k127_7773956_2 alcohol dehydrogenase K00121,K00153 - 1.1.1.1,1.1.1.284,1.1.1.306 0.0000000000041 70.0
HFD2_k127_7773956_3 - - - - 0.000002667 54.0
HFD2_k127_7778837_0 mandelate racemase muconate lactonizing K18983 - 5.5.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 374.0
HFD2_k127_7778837_1 Putative restriction endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000003727 212.0
HFD2_k127_7796674_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000007367 226.0
HFD2_k127_7796674_1 Protein kinase domain K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000001378 223.0
HFD2_k127_7796674_2 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000000002491 125.0
HFD2_k127_7796674_3 dUTPase K01520 - 3.6.1.23 0.000000000000000000003164 98.0
HFD2_k127_7796674_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000004684 79.0
HFD2_k127_7807074_0 acyl-CoA transferases carnitine dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 388.0
HFD2_k127_7807074_1 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008249 340.0
HFD2_k127_7807074_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000002469 244.0
HFD2_k127_7807074_3 Belongs to the FPG family K05522 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000001815 229.0
HFD2_k127_7807074_4 Psort location CytoplasmicMembrane, score - - - 0.000008787 58.0
HFD2_k127_7811959_0 aromatic amino acid beta-eliminating lyase threonine aldolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000051 388.0
HFD2_k127_7811959_1 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008989 309.0
HFD2_k127_7811959_2 Methyltransferase type 12 - - - 0.000000000000000000000000000000000000000000000000000000000892 209.0
HFD2_k127_7811959_3 MoaE protein K21142 - 2.8.1.12 0.0000000000000000000000000000000000003211 142.0
HFD2_k127_7811959_4 Bacterial membrane protein YfhO - - - 0.000000000000000000000000000001875 138.0
HFD2_k127_7818741_0 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A K02006,K02188 - 2.1.1.195 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000489 383.0
HFD2_k127_7818741_1 AAA domain (dynein-related subfamily) K03404,K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008671 295.0
HFD2_k127_7818741_2 Cobalamin biosynthesis protein CbiE K00595 - 2.1.1.132 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001378 292.0
HFD2_k127_7818741_3 Tetrapyrrole (Corrin/Porphyrin) Methylases K05936 - 2.1.1.133,2.1.1.271 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003555 276.0
HFD2_k127_7818741_4 Belongs to the precorrin methyltransferase family K13541 - 2.1.1.131,3.7.1.12 0.0000000000000000000000000000000000000000000000000005131 197.0
HFD2_k127_7818741_5 PFAM Precorrin-8X methylmutase K06042 - 5.4.99.60,5.4.99.61 0.0000000000000000000000000000000000000000000000001385 184.0
HFD2_k127_7818741_6 Precorrin-2 C20-methyltransferase K03394 - 2.1.1.130,2.1.1.151 0.0000000000000000000000000000000000000000000000002401 184.0
HFD2_k127_7818741_7 GIY-YIG catalytic domain K07461 - - 0.0000001815 53.0
HFD2_k127_7822206_0 Multicopper oxidase K00368,K22348 - 1.16.3.3,1.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007155 313.0
HFD2_k127_7822206_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000005041 220.0
HFD2_k127_7822206_2 Luciferase-like monooxygenase K04091,K20938 - 1.14.14.28,1.14.14.5 0.0000000000000000000000006202 110.0
HFD2_k127_7826923_0 Amidohydrolase family K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000192 227.0
HFD2_k127_7827567_0 PFAM ABC transporter related K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 494.0
HFD2_k127_7827567_1 LVIVD repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 370.0
HFD2_k127_7827567_2 PFAM NAD dependent epimerase dehydratase family K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 316.0
HFD2_k127_7827567_3 exodeoxyribonuclease I activity - - - 0.00000000000000000000000000000000000002697 149.0
HFD2_k127_7827567_4 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000000000000000000003532 142.0
HFD2_k127_7827567_5 Arylsulfotransferase (ASST) - - - 0.00000000000000006485 96.0
HFD2_k127_7831355_0 Nitrite and sulphite reductase 4Fe-4S domain K00366,K00392 - 1.7.7.1,1.8.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006403 404.0
HFD2_k127_7831355_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00367 - 1.7.7.2 0.000000000000000000000000000000000000000000000000000000000208 211.0
HFD2_k127_7832365_0 COG0330 Membrane protease subunits, stomatin prohibitin homologs - - - 0.000000000000000000000000000000000000001152 160.0
HFD2_k127_7836957_0 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 390.0
HFD2_k127_7836957_1 Isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000336 272.0
HFD2_k127_7836957_2 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000001447 211.0
HFD2_k127_7836957_3 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000001873 147.0
HFD2_k127_7836957_4 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000006005 76.0
HFD2_k127_7847612_0 ATP-cone domain protein K00525 - 1.17.4.1 0.0 1022.0
HFD2_k127_7847612_1 Thioredoxin-like domain K03671 - - 0.000001286 50.0
HFD2_k127_7854853_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 380.0
HFD2_k127_7854853_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000873 285.0
HFD2_k127_7860770_0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family - - - 0.00000000000000000000000000000000000000001866 161.0
HFD2_k127_7860770_1 ribonuclease activity - GO:0005575,GO:0005576,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113 - 0.0009163 43.0
HFD2_k127_7861172_0 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000846 252.0
HFD2_k127_7861172_1 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000001285 230.0
HFD2_k127_7864676_0 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000941 298.0
HFD2_k127_7864676_1 NAD(P)-binding Rossmann-like domain K00303 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000001517 240.0
HFD2_k127_7864676_2 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000448 203.0
HFD2_k127_7872378_0 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K03417 - 4.1.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 311.0
HFD2_k127_7872378_1 O-Antigen ligase - - - 0.0000000000000000000000000000000000000001373 157.0
HFD2_k127_7872378_2 AI-2E family transporter K03548 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.00000000000000000000000000000000003296 149.0
HFD2_k127_7885993_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004921 374.0
HFD2_k127_7888101_0 Catalyzes the transformation of hydroxyatrazine to N-isopropylammelide and ethylamine in the atrazine degradation pathway K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009881 308.0
HFD2_k127_789263_0 TCP-1/cpn60 chaperonin family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 332.0
HFD2_k127_7898853_0 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000004651 189.0
HFD2_k127_7898853_1 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000002768 188.0
HFD2_k127_7898853_2 NAD binding K00058 - 1.1.1.399,1.1.1.95 0.000000000000000001751 93.0
HFD2_k127_7900431_0 Myo-inositol-1-phosphate synthase, GAPDH domain protein K01858 - 5.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003516 597.0
HFD2_k127_7900431_1 COG0044 Dihydroorotase and related cyclic amidohydrolases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 574.0
HFD2_k127_7900431_2 Periplasmic binding protein LacI transcriptional regulator K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001835 282.0
HFD2_k127_7900431_3 Asparaginase - - - 0.00000000000000001076 83.0
HFD2_k127_7917875_0 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 585.0
HFD2_k127_7917875_1 short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008913 289.0
HFD2_k127_7917875_2 Protein of unknown function (DUF1385) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001954 272.0
HFD2_k127_7917875_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.0000000000000000000000000000000000000000000000007974 186.0
HFD2_k127_7917875_4 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000002799 129.0
HFD2_k127_7917875_5 Binds the 23S rRNA K02909 - - 0.0000000000000000000000006394 106.0
HFD2_k127_7917875_6 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000023 106.0
HFD2_k127_7917875_7 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000001958 98.0
HFD2_k127_7917875_8 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0003674,GO:0003735,GO:0005198 - 0.00000005864 59.0
HFD2_k127_7918011_0 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 8.386e-315 974.0
HFD2_k127_7918011_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 4.912e-245 764.0
HFD2_k127_7918011_10 ADP-heptose-lipopolysaccharide heptosyltransferase activity - - - 0.000000000000000000000000000000000000000006644 169.0
HFD2_k127_7918011_12 ATP-dependent protease La (LON) substrate-binding domain K01338,K07157 - 3.4.21.53 0.0000000000000000000000000000000000000005868 155.0
HFD2_k127_7918011_13 COG2087 Adenosyl cobinamide kinase adenosyl cobinamide phosphate guanylyltransferase K02231 - 2.7.1.156,2.7.7.62 0.00000000000000000000000000000000000001067 153.0
HFD2_k127_7918011_14 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.0000000000000000000000000000009638 133.0
HFD2_k127_7918011_15 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.000000000000000000000000000002068 126.0
HFD2_k127_7918011_16 PFAM YdjC family protein K03478 - 3.5.1.105 0.00000000000000000000000000003094 129.0
HFD2_k127_7918011_17 transporter - - - 0.000000000000000000000000008409 126.0
HFD2_k127_7918011_18 Alpha/beta hydrolase family - - - 0.0000000001253 68.0
HFD2_k127_7918011_2 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K05365 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 589.0
HFD2_k127_7918011_3 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 459.0
HFD2_k127_7918011_4 PFAM Peptidase family M20 M25 M40 K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 380.0
HFD2_k127_7918011_5 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006888 376.0
HFD2_k127_7918011_6 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 366.0
HFD2_k127_7918011_7 Amidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 359.0
HFD2_k127_7918011_8 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000007106 208.0
HFD2_k127_7918011_9 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000004106 186.0
HFD2_k127_7923956_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 510.0
HFD2_k127_7923956_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000001829 227.0
HFD2_k127_792501_0 N-methylhydantoinase B acetone carboxylase, alpha subunit K01474 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 344.0
HFD2_k127_792501_1 Hydantoinase/oxoprolinase K01469,K01473 - 3.5.2.14,3.5.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000092 310.0
HFD2_k127_792501_2 5-oxoprolinase K01473 - 3.5.2.14 0.000000000000000000000000009484 114.0
HFD2_k127_792501_3 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.00000000000000000000000001087 115.0
HFD2_k127_792501_4 Hydantoinase/oxoprolinase K01469,K01473 - 3.5.2.14,3.5.2.9 0.0000000000000000001482 91.0
HFD2_k127_7925024_0 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001788 279.0
HFD2_k127_7925024_1 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000002022 218.0
HFD2_k127_7925024_2 4-amino-4-deoxy-L-arabinose transferase activity K14340 - - 0.000000000000000000002209 109.0
HFD2_k127_7925024_3 PFAM transposase, IS4 family protein - - - 0.00000000002221 67.0
HFD2_k127_7928384_0 Sodium:sulfate symporter transmembrane region K03319 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002995 533.0
HFD2_k127_7928384_1 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 408.0
HFD2_k127_7928384_2 Alanine dehydrogenase/PNT, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000005104 229.0
HFD2_k127_7928384_3 PFAM Endonuclease exonuclease phosphatase - - - 0.00000000000000000000000000000000001301 149.0
HFD2_k127_7928384_4 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000001195 70.0
HFD2_k127_7937916_0 EXOIII K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 377.0
HFD2_k127_7937916_1 Two component transcriptional regulator, winged helix family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000294 285.0
HFD2_k127_7937916_2 Esterase of the alpha-beta hydrolase superfamily - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000721 258.0
HFD2_k127_7937916_3 Esterase of the alpha-beta hydrolase superfamily - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000001524 80.0
HFD2_k127_7939242_0 Heparinase II/III-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 331.0
HFD2_k127_7955444_0 PFAM Enoyl-CoA hydratase isomerase K01692,K15866 - 4.2.1.17,5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001001 283.0
HFD2_k127_7955444_1 PFAM Enoyl-CoA hydratase isomerase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000002411 259.0
HFD2_k127_7955444_2 phenylacetic acid degradation protein PaaD K02614 - - 0.00000000000000000000000004498 115.0
HFD2_k127_7960764_0 Cytochrome c oxidase subunit K02274 - 1.9.3.1 2.787e-215 682.0
HFD2_k127_7960764_1 AAA domain K07028 - - 0.0000000000000000000000000000000000000000000000000000000000001728 220.0
HFD2_k127_7960764_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000007722 135.0
HFD2_k127_7960764_3 Heme copper-type cytochrome quinol oxidases, subunit 2 K02275 - 1.9.3.1 0.000000000000000000000000009617 115.0
HFD2_k127_7960764_4 COG2010 Cytochrome c, mono- and diheme variants - - - 0.0000000000000000000003816 102.0
HFD2_k127_7982808_0 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate K00108 - 1.1.99.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 396.0
HFD2_k127_7982808_1 Pentapeptide repeats (9 copies) - - - 0.00000000000000002023 95.0
HFD2_k127_7983864_0 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 369.0
HFD2_k127_7983864_1 4Fe-4S dicluster domain K11473 - - 0.000000000000000000000000000000000000000000000000000000000000321 219.0
HFD2_k127_7983864_2 ThiS family K03636 - - 0.000000000000000000000000006288 111.0
HFD2_k127_7983864_3 NIL - - - 0.0000000000000001474 84.0
HFD2_k127_7992_0 Ring hydroxylating alpha subunit (catalytic domain) K03268,K05708 - 1.14.12.11,1.14.12.19,1.14.12.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 553.0
HFD2_k127_7992_1 Pyridoxal phosphate biosynthetic protein PdxA K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008392 372.0
HFD2_k127_7992_2 Acyl-CoA dehydrogenase, C-terminal domain K22027 - 1.14.13.235 0.000000000000000000000000000000000000000000000000000000000000000000002428 251.0
HFD2_k127_7992_3 Ring hydroxylating beta subunit K15750 - 1.14.12.18 0.0000000000000000000000000000000000000000000000000000000000002835 216.0
HFD2_k127_7992_4 Family 5 K02035 - - 0.000000000000000000000000000000000000000002162 176.0
HFD2_k127_7992_5 Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system - - - 0.0000000000000000000000000004866 115.0
HFD2_k127_7992_6 - - - - 0.000007018 51.0
HFD2_k127_8001109_0 PFAM Haloacid dehalogenase domain protein hydrolase K01101 - 3.1.3.41 0.000000000000000000000000000000000000000000000000000000000000000005456 233.0
HFD2_k127_8001109_1 - - - - 0.000000000000000000000000000001615 136.0
HFD2_k127_8001109_2 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway K03707 - 3.5.99.2 0.00000000000006908 72.0
HFD2_k127_8011640_0 Domain of unknown function (DUF1998) K06877 - - 4.861e-303 948.0
HFD2_k127_8011640_1 Exonuclease K07502 - - 0.000000000000000000000000000000000000000000000000000000000000000009617 235.0
HFD2_k127_8018923_0 asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 359.0
HFD2_k127_8034154_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 442.0
HFD2_k127_8034154_1 Acetyltransferase (GNAT) domain - - - 0.00000000003427 72.0
HFD2_k127_8036914_0 Urease alpha-subunit, N-terminal domain K01427,K01428 - 3.5.1.5 4.831e-254 795.0
HFD2_k127_8036914_1 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002698 280.0
HFD2_k127_8036914_2 Belongs to the urease beta subunit family K01429 GO:0003674,GO:0003824,GO:0006807,GO:0008150,GO:0008152,GO:0009039,GO:0016787,GO:0016810,GO:0016811 3.5.1.5 0.000000000000000000000000000000000000006697 148.0
HFD2_k127_8036914_3 Belongs to the urease gamma subunit family K01430,K14048 - 3.5.1.5 0.0000000000000000000000000000000000008232 143.0
HFD2_k127_8036914_4 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03190 - - 0.0000000000000000000000000000000001522 146.0
HFD2_k127_8036914_5 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03188 - - 0.00000000000000000000000000000009795 132.0
HFD2_k127_8045445_0 4Fe-4S dicluster domain - - - 4.824e-215 688.0
HFD2_k127_8045445_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003725 551.0
HFD2_k127_8045445_10 NifU-like N terminal domain K04488 - - 0.00000000000000000000000000000000000004064 146.0
HFD2_k127_8045445_11 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.0000000000000000000007315 99.0
HFD2_k127_8045445_12 Protein of unknown function DUF111 K06898,K09121 - 4.99.1.12 0.000000001001 70.0
HFD2_k127_8045445_2 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 456.0
HFD2_k127_8045445_3 PFAM Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002676 460.0
HFD2_k127_8045445_4 electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006128 283.0
HFD2_k127_8045445_5 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000002685 252.0
HFD2_k127_8045445_6 AIR carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000001092 244.0
HFD2_k127_8045445_7 electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000000000000000000000000000002526 226.0
HFD2_k127_8045445_8 PA domain - - - 0.00000000000000000000000000000000000000000000000000000000461 220.0
HFD2_k127_8045445_9 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000000000000000000000000000000000000005792 157.0
HFD2_k127_8045893_0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000008755 199.0
HFD2_k127_8045893_1 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000000000000006588 170.0
HFD2_k127_8045893_2 FMN_bind - - - 0.0000001975 59.0
HFD2_k127_8045893_3 - - - - 0.0000002511 56.0
HFD2_k127_8084854_0 Amidohydrolase - - - 0.000000000000000000000001663 105.0
HFD2_k127_8084854_1 Soluble NSF attachment protein, SNAP - - - 0.0006493 51.0
HFD2_k127_8085185_0 Protein of unknown function (DUF2867) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 520.0
HFD2_k127_8085185_1 COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) K05770 - - 0.000000000000000000000000005692 119.0
HFD2_k127_8096069_0 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 400.0
HFD2_k127_8096069_1 inositol 2-dehydrogenase activity - - - 0.0000000000000000000001162 103.0
HFD2_k127_8096069_2 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.0000000000003643 71.0
HFD2_k127_8097135_0 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 417.0
HFD2_k127_8097135_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004781 286.0
HFD2_k127_8097135_2 Enoyl-CoA hydratase/isomerase K11264 - 4.1.1.41 0.00000000000000000000000000000000000000000004814 170.0
HFD2_k127_8097135_3 Cupin 2, conserved barrel domain protein K11312 - - 0.000000000000000002757 88.0
HFD2_k127_8097135_4 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.0000000001171 69.0
HFD2_k127_8101157_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 3.122e-224 704.0
HFD2_k127_8101157_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000000002644 188.0
HFD2_k127_8101157_2 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000007674 141.0
HFD2_k127_8101157_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000006955 113.0
HFD2_k127_8101157_4 Zinc metalloprotease (Elastase) - - - 0.0000000000000000000003708 103.0
HFD2_k127_8101157_5 ATP synthase B/B' CF(0) K02109 - - 0.00000000000000006429 87.0
HFD2_k127_8101157_6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000276 83.0
HFD2_k127_8101157_7 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.00001435 52.0
HFD2_k127_8105227_0 Alkanesulfonate monooxygenase K04091 - 1.14.14.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002588 272.0
HFD2_k127_8105227_1 Phosphoenolpyruvate phosphomutase K20454 - 4.1.3.32 0.000000000000000000000000000000000000000000000000000000000000000000000002322 254.0
HFD2_k127_8105227_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000002307 192.0
HFD2_k127_8111119_0 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006883 366.0
HFD2_k127_8111119_1 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 288.0
HFD2_k127_8111119_2 PFAM 6-pyruvoyl tetrahydropterin synthase and K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000004121 166.0
HFD2_k127_8125938_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 536.0
HFD2_k127_8125938_1 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006811 503.0
HFD2_k127_8125938_2 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 315.0
HFD2_k127_8125938_3 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000009565 235.0
HFD2_k127_8125938_4 Bacterial membrane protein YfhO - - - 0.00000000000000000000000000002412 128.0
HFD2_k127_8125938_5 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000002152 115.0
HFD2_k127_8125938_6 Putative cyclase - - - 0.000107 49.0
HFD2_k127_8130395_0 Pyridoxal-dependent decarboxylase conserved domain K01593,K01634 - 4.1.1.105,4.1.1.28,4.1.2.27 1.016e-200 643.0
HFD2_k127_8130395_1 - - - - 0.0000000000000000000000000000332 130.0
HFD2_k127_8130395_2 Serine aminopeptidase, S33 - - - 0.00000000000000000001104 99.0
HFD2_k127_8134755_0 Belongs to the glycosyl hydrolase 57 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 481.0
HFD2_k127_8134755_1 Belongs to the class-I aminoacyl-tRNA synthetase family K15526 - 6.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 421.0
HFD2_k127_8134755_2 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 308.0
HFD2_k127_8134755_3 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000002497 211.0
HFD2_k127_8134755_4 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family - - - 0.0000000000000000000000000000000000000000000000000002388 194.0
HFD2_k127_8134755_5 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000006376 151.0
HFD2_k127_8134755_6 Belongs to the class-I aminoacyl-tRNA synthetase family - - - 0.0000000000000000000000000572 119.0
HFD2_k127_8134755_7 (Rieske (2Fe-2S) domain) K00363,K05710 - 1.7.1.15 0.000000000000000000000001032 107.0
HFD2_k127_8134755_8 PFAM blue (type 1) copper domain protein - - - 0.00000000000000007644 91.0
HFD2_k127_8141017_0 abc transporter atp-binding protein K06147,K18888 - - 0.00000000000001702 87.0
HFD2_k127_8144896_0 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000001036 193.0
HFD2_k127_8147723_0 MFS_1 like family K08161 - - 0.00000000000000000000000000000000000000000000000001208 195.0
HFD2_k127_8147723_1 LysE type translocator - - - 0.00000000000000000000000000000953 129.0
HFD2_k127_8147723_2 ParB-like nuclease domain K03497 - - 0.00000000000000000000000000003627 129.0
HFD2_k127_8147723_3 EamA-like transporter family - - - 0.0000000001933 72.0
HFD2_k127_8147723_4 Fibronectin type III domain protein - - - 0.000002482 60.0
HFD2_k127_8147723_5 DinB superfamily - - - 0.000127 51.0
HFD2_k127_8154419_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000003191 183.0
HFD2_k127_8157718_0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000001708 216.0
HFD2_k127_8157718_1 membrane - - - 0.0000001072 59.0
HFD2_k127_8157718_2 membrane - - - 0.000008054 52.0
HFD2_k127_8177178_0 Belongs to the pyruvate kinase family K00873 GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 451.0
HFD2_k127_8177178_1 Putative cyclase K07130 - 3.5.1.9 0.0000000000000000000000000000000000000000000000000000000003747 209.0
HFD2_k127_8177178_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000003717 150.0
HFD2_k127_8186882_0 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000003706 197.0
HFD2_k127_8186882_1 Uncharacterized conserved protein (DUF2277) - - - 0.000000005175 60.0
HFD2_k127_8186882_2 COG1061 DNA or RNA helicases of superfamily II - - - 0.000179 55.0
HFD2_k127_8189780_0 Glycosyl transferase, WecB TagA CpsF family K05946 - 2.4.1.187 0.00000000000000000000000000000000000000000000000000000000000000003213 233.0
HFD2_k127_8189780_1 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000005294 230.0
HFD2_k127_8189780_2 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000001246 206.0
HFD2_k127_8189780_3 DNA polymerase alpha chain like domain K01624,K07053 - 3.1.3.97,4.1.2.13 0.000000000000000000000000000000000000001046 153.0
HFD2_k127_8189780_4 Epimerase dehydratase K06118 - 3.13.1.1 0.0000003764 62.0
HFD2_k127_8192438_0 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 5.881e-202 636.0
HFD2_k127_8192438_1 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 453.0
HFD2_k127_8192438_2 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004783 362.0
HFD2_k127_8192438_3 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 346.0
HFD2_k127_8192438_4 PFAM Methionine synthase, vitamin-B12 independent K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 311.0
HFD2_k127_8192438_5 PrpF protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001018 263.0
HFD2_k127_8192438_6 Phosphotriesterase family K07048 - - 0.0000000000004999 78.0
HFD2_k127_8192438_7 membrane - - - 0.000000000001629 80.0
HFD2_k127_8198090_0 Putative glycosyl hydrolase domain - - - 0.000000000000000000000000000000000000000008606 169.0
HFD2_k127_8198090_1 Cytidylate kinase-like family - - - 0.000778 46.0
HFD2_k127_8200121_0 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000009775 230.0
HFD2_k127_8200121_1 Secreted repeat of unknown function - - - 0.0000000000000000000000000000000198 138.0
HFD2_k127_8205044_0 MgtE intracellular N domain K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003589 446.0
HFD2_k127_8205044_1 Belongs to the DegT DnrJ EryC1 family K16436 - 2.6.1.106 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007794 341.0
HFD2_k127_8205044_2 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000208 197.0
HFD2_k127_8226165_0 Putative nucleotide-binding of sugar-metabolising enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009913 389.0
HFD2_k127_8226165_1 Xylose isomerase-like TIM barrel K01816 - 5.3.1.22 0.000000000000000000000000000002643 121.0
HFD2_k127_8226165_2 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000002034 66.0
HFD2_k127_8226165_3 Sulfatase - - - 0.0000001308 59.0
HFD2_k127_8240310_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 436.0
HFD2_k127_8240310_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000006986 236.0
HFD2_k127_8240310_2 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000002729 224.0
HFD2_k127_8240310_3 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000002073 213.0
HFD2_k127_8240310_4 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000002137 161.0
HFD2_k127_8240310_5 PFAM Histidine triad (HIT) protein K02503 - - 0.000000000000000000000000000000000001232 147.0
HFD2_k127_8240310_6 RNA methyltransferase, RsmD family K08316 - 2.1.1.171 0.000000000000000000000000002592 119.0
HFD2_k127_8240310_7 MaoC like domain - - - 0.00000000000000000000000008977 111.0
HFD2_k127_8240310_8 negative regulation of DNA recombination - - - 0.000000000000000002294 97.0
HFD2_k127_8240310_9 Ribosomal L28 family K02902 - - 0.0000000000002508 75.0
HFD2_k127_8243115_0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074,K01782 - 1.1.1.157,1.1.1.35,4.2.1.17,5.1.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 347.0
HFD2_k127_8243115_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000003565 117.0
HFD2_k127_8243115_2 Serine aminopeptidase, S33 - - - 0.00000000002772 75.0
HFD2_k127_8243965_0 polysaccharide catabolic process K03478 - 3.5.1.105 0.000000000000000000000000000000000000000000000000000000000000000000000002755 250.0
HFD2_k127_8243965_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000003246 205.0
HFD2_k127_8245288_0 PFAM glycosyl transferase group 1 - - - 6.029e-266 837.0
HFD2_k127_8245288_1 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009747 291.0
HFD2_k127_8245288_2 tRNA (guanine(37)-N(1))-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000001185 231.0
HFD2_k127_8249204_0 PFAM FAD linked oxidase domain protein K00102,K00104 - 1.1.2.4,1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 497.0
HFD2_k127_8249204_1 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003975 485.0
HFD2_k127_8261644_0 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004777 548.0
HFD2_k127_8261644_1 - - - - 0.0000000000000000000000000000000001716 146.0
HFD2_k127_8261644_2 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000002619 125.0
HFD2_k127_8261644_3 COG0831 Urea amidohydrolase (urease) gamma subunit - - - 0.0000000000000000000000000002264 117.0
HFD2_k127_8261644_4 Belongs to the urease beta subunit family K01429,K14048 - 3.5.1.5 0.0000000000000000000000007634 107.0
HFD2_k127_8265697_0 Extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 324.0
HFD2_k127_8265697_1 - - - - 0.000000000000000000000000000000000000002693 150.0
HFD2_k127_8265697_3 - - - - 0.000002198 52.0
HFD2_k127_8270188_0 Beta-lactamase K01467 - 3.5.2.6 0.00000000000000000000000000000000000000000000001212 179.0
HFD2_k127_8270188_1 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.0000000001453 70.0
HFD2_k127_8270188_2 Methyltransferase domain - - - 0.0000000002981 72.0
HFD2_k127_8270269_0 COG0657 Esterase lipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 330.0
HFD2_k127_8270269_1 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007638 295.0
HFD2_k127_8270269_2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding - - - 0.0000000000000000000000000000000000000000000006897 173.0
HFD2_k127_8277619_0 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 616.0
HFD2_k127_8277619_1 Poly A polymerase head domain K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 456.0
HFD2_k127_8277619_10 Ribosomal protein L35 K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000002482 55.0
HFD2_k127_8277619_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 394.0
HFD2_k127_8277619_3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000004141 179.0
HFD2_k127_8277619_4 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000000001804 149.0
HFD2_k127_8277619_5 PFAM Haloacid dehalogenase domain protein hydrolase K07025 - - 0.00000000000000000000002281 110.0
HFD2_k127_8277619_6 GDSL-like Lipase/Acylhydrolase - - - 0.0000000000000000002572 100.0
HFD2_k127_8277619_7 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000001454 72.0
HFD2_k127_8277619_8 SPTR Q2LSA8 Transposase and inactivated derivatives - - - 0.000000001762 58.0
HFD2_k127_8280395_0 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 442.0
HFD2_k127_8280395_1 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 365.0
HFD2_k127_8280395_2 PFAM MmgE PrpD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008631 356.0
HFD2_k127_8280395_3 lipolytic protein G-D-S-L family - - - 0.00000000000000000003019 98.0
HFD2_k127_8281147_0 Glycosyl transferase, family 4 K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003765 288.0
HFD2_k127_8286061_0 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000002427 243.0
HFD2_k127_8286061_1 endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000004403 159.0
HFD2_k127_8286061_2 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) - - - 0.000000000000000000000000000000000001761 142.0
HFD2_k127_8286061_3 - - - - 0.000000000000000000000000000145 127.0
HFD2_k127_8286061_4 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.000000000000000000000000359 115.0
HFD2_k127_8286061_5 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000009636 100.0
HFD2_k127_8286061_6 PFAM metal-dependent phosphohydrolase, HD sub domain K01524,K06950 - 3.6.1.11,3.6.1.40 0.0000000000008218 81.0
HFD2_k127_8286061_7 Domain of unknown function (DUF4956) - - - 0.00000001849 65.0
HFD2_k127_8286061_8 CHAD - - - 0.0001774 52.0
HFD2_k127_8290819_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 372.0
HFD2_k127_8290819_1 SMART Nucleotide binding protein, PINc - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004548 267.0
HFD2_k127_8306933_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000002922 225.0
HFD2_k127_8306933_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000259 218.0
HFD2_k127_8306933_2 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000000000000000007917 186.0
HFD2_k127_8306933_3 Putative regulatory protein - - - 0.00000000000000000008979 93.0
HFD2_k127_8306933_4 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000007552 55.0
HFD2_k127_8317422_0 Amino acid permease - - - 7.98e-197 635.0
HFD2_k127_8317422_1 PFAM ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000523 307.0
HFD2_k127_8317422_2 mandelate racemase muconate lactonizing K20023 - 4.2.1.156,4.2.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000005071 250.0
HFD2_k127_8317422_3 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001966 254.0
HFD2_k127_8328125_0 short-chain dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 298.0
HFD2_k127_8328125_1 HELICc2 K03722 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000645 237.0
HFD2_k127_8328125_2 CorA-like Mg2+ transporter protein K03284 - - 0.000000000000000006946 84.0
HFD2_k127_8328125_3 - - - - 0.000031 53.0
HFD2_k127_8342276_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 324.0
HFD2_k127_8342276_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009931 288.0
HFD2_k127_8343042_0 Belongs to the glycosyl hydrolase 26 family - - - 0.000000000000000000000003912 109.0
HFD2_k127_8343042_1 ArsC family - - - 0.0000000000006403 72.0
HFD2_k127_8344917_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008426 408.0
HFD2_k127_8344917_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004608 275.0
HFD2_k127_8344917_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0005488,GO:0036094,GO:0048037,GO:0050661,GO:0050662,GO:0097159,GO:1901265,GO:1901363 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000002403 218.0
HFD2_k127_8344917_3 Domain of unknown function (DUF4115) - - - 0.0000000000000000000000001642 121.0
HFD2_k127_8348878_0 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005108 334.0
HFD2_k127_8348878_1 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001417 267.0
HFD2_k127_8348878_2 Asp Glu Hydantoin racemase K01799 - 5.2.1.1 0.000006599 57.0
HFD2_k127_8348878_3 NAD dependent epimerase dehydratase family protein K01784 - 5.1.3.2 0.00005725 48.0
HFD2_k127_8394374_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008215 396.0
HFD2_k127_8394374_1 NAD dependent epimerase/dehydratase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005862 255.0
HFD2_k127_8394374_2 PFAM PKD domain containing protein - - - 0.000000000000000000000006505 115.0
HFD2_k127_8403932_0 PFAM fumarylacetoacetate (FAA) hydrolase K16171 - 3.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 331.0
HFD2_k127_8403932_1 with different specificities (related to short-chain alcohol - - - 0.00000000000000000000000000000000000000000000000000005806 196.0
HFD2_k127_8403932_2 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000002198 52.0
HFD2_k127_8405791_0 ABC transporter, transmembrane region K06147,K18890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009232 420.0
HFD2_k127_8405791_1 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000002074 214.0
HFD2_k127_8407876_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000004216 194.0
HFD2_k127_8407876_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000001098 64.0
HFD2_k127_8410360_0 Belongs to the Glu Leu Phe Val dehydrogenases family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 501.0
HFD2_k127_8410360_1 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit K00166 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 301.0
HFD2_k127_84149_0 Methionine synthase B12-binding module cap domain protein K00548,K15023 - 2.1.1.13,2.1.1.258 2.231e-255 804.0
HFD2_k127_8415483_0 Family 5 K02035 - - 0.0000000000000000000000000000000000000000056 173.0
HFD2_k127_8415483_1 Belongs to the glycosyl hydrolase 26 family - - - 0.00000000000000000000000000000000000003481 156.0
HFD2_k127_841955_0 AAA ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005499 475.0
HFD2_k127_841955_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006104 447.0
HFD2_k127_841955_10 PFAM Peptidase family M23 - - - 0.0000003407 59.0
HFD2_k127_841955_2 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000004624 242.0
HFD2_k127_841955_3 NUDIX domain - - - 0.00000000000000000000000000000000000000005534 156.0
HFD2_k127_841955_4 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.0000000000000000000002481 109.0
HFD2_k127_841955_5 Histidine kinase - - - 0.00000000000000000001097 97.0
HFD2_k127_841955_6 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000001946 89.0
HFD2_k127_841955_7 Involved in the tonB-independent uptake of proteins - - - 0.000000000000001448 88.0
HFD2_k127_841955_8 Malate/L-lactate dehydrogenase K13574 - - 0.0000000000001105 75.0
HFD2_k127_841955_9 Belongs to the LDH2 MDH2 oxidoreductase family - - - 0.00000003619 60.0
HFD2_k127_8432041_0 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 - 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008207 457.0
HFD2_k127_8432041_1 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006758 289.0
HFD2_k127_8432041_2 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000154 274.0
HFD2_k127_8432041_3 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000002539 249.0
HFD2_k127_8432041_4 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000003368 199.0
HFD2_k127_8432041_5 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.0000000003047 66.0
HFD2_k127_8432041_6 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008289,GO:0008689,GO:0008757,GO:0009058,GO:0009108,GO:0009628,GO:0009651,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0042538,GO:0043167,GO:0043168,GO:0043431,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0051188,GO:0061542,GO:0071704,GO:1901576,GO:1901611,GO:1901661,GO:1901663 2.1.1.222,2.1.1.64 0.000007325 57.0
HFD2_k127_8433212_0 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000146 253.0
HFD2_k127_8433212_1 PFAM MgtC SapB transporter - - - 0.00000000001156 74.0
HFD2_k127_8449294_0 PBP superfamily domain K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004515 333.0
HFD2_k127_8449294_1 TIGRFAM molybdenum cofactor synthesis K03750,K07219 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000007814 212.0
HFD2_k127_8449294_2 helix_turn_helix gluconate operon transcriptional repressor - - - 0.000000000003995 78.0
HFD2_k127_8454578_0 PFAM glycosyl transferase family 39 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000842 261.0
HFD2_k127_8454578_1 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000009789 126.0
HFD2_k127_8454578_2 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000005387 97.0
HFD2_k127_845866_0 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 304.0
HFD2_k127_845866_1 ABC-type multidrug transport system, permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001474 278.0
HFD2_k127_8463751_0 Molydopterin dinucleotide binding domain K07306,K07309,K07310,K08352 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009390,GO:0009897,GO:0009986,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0032991,GO:0033797,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071944,GO:0098552,GO:0098567,GO:1902494 1.8.5.3,1.8.5.5,1.97.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005492 626.0
HFD2_k127_8463751_1 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 527.0
HFD2_k127_8463751_2 Two component transcriptional regulator, LuxR family - - - 0.000000000000000000000000000000000000000000000000000000000000005981 225.0
HFD2_k127_8463751_3 MFS_1 like family - - - 0.0000000000000000000000000000000000000000000000000000001085 211.0
HFD2_k127_8463751_4 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000001457 111.0
HFD2_k127_8465701_0 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000001876 172.0
HFD2_k127_8465701_1 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000002202 128.0
HFD2_k127_8468992_0 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004896 302.0
HFD2_k127_8473004_0 4,5-dihydroxyphthalate decarboxylase K04102 - 4.1.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000004202 255.0
HFD2_k127_8473004_1 4,5-dihydroxyphthalate decarboxylase K04102 - 4.1.1.55 0.0000000000000000000000000000000007939 132.0
HFD2_k127_8473004_2 Aldo/keto reductase family - - - 0.000003356 51.0
HFD2_k127_8476125_0 PFAM ExsB family protein K06864 - - 0.0000000000000000000000000001258 118.0
HFD2_k127_8476125_1 - - - - 0.00003106 49.0
HFD2_k127_8500680_0 ABC-type Fe3 transport system permease component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006736 551.0
HFD2_k127_8500680_1 Amidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 414.0
HFD2_k127_8500680_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007346 403.0
HFD2_k127_8500680_3 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 376.0
HFD2_k127_8500680_4 iron ion homeostasis K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000002412 244.0
HFD2_k127_8500680_5 Bacterial extracellular solute-binding protein - - - 0.00000000000000000000000000000000000000000000002896 186.0
HFD2_k127_8500680_6 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.000000000000000000000002946 106.0
HFD2_k127_8511742_0 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000537 430.0
HFD2_k127_8511742_1 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007582 300.0
HFD2_k127_8511742_2 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006145 248.0
HFD2_k127_8519499_0 CoA-transferase family III K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 407.0
HFD2_k127_8519499_1 Rhodanese Homology Domain K01011,K21028 - 2.8.1.1,2.8.1.11,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 385.0
HFD2_k127_8519499_2 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000001586 223.0
HFD2_k127_8519499_3 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000009941 211.0
HFD2_k127_8519499_4 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000008125 146.0
HFD2_k127_8519499_5 PFAM Methyltransferase type 11 - - - 0.0000000000000000000004768 107.0
HFD2_k127_8519499_6 2-keto-4-pentenoate hydratase - - - 0.0000000000000001724 83.0
HFD2_k127_8521605_0 Luciferase-like monooxygenase - - - 0.00000004169 56.0
HFD2_k127_8522814_0 PFAM Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 425.0
HFD2_k127_8522814_1 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002502 274.0
HFD2_k127_8522814_2 Belongs to the thiolase family - - - 0.0000000000000000925 87.0
HFD2_k127_8537659_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005158 245.0
HFD2_k127_8537659_1 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000536 230.0
HFD2_k127_8538521_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 536.0
HFD2_k127_8538521_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000298 404.0
HFD2_k127_8538521_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 333.0
HFD2_k127_8538521_3 PFAM ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009476 273.0
HFD2_k127_8538521_4 Required for chromosome condensation and partitioning K03529 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000002514 234.0
HFD2_k127_8538521_5 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000006296 171.0
HFD2_k127_8538521_6 Putative regulatory protein - - - 0.00000000000000000000000000000002948 131.0
HFD2_k127_8541910_0 Transketolase, pyrimidine binding domain K21417 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007992 436.0
HFD2_k127_8541910_1 FMN-dependent dehydrogenase K00101,K15054,K16422 - 1.1.2.3,1.1.3.46,1.1.99.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004731 398.0
HFD2_k127_8541910_10 Cupin domain - - - 0.00007976 50.0
HFD2_k127_8541910_11 VTC domain - - - 0.0002198 51.0
HFD2_k127_8541910_2 E1 component K21416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009127 357.0
HFD2_k127_8541910_3 DNA-3-methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000001961 255.0
HFD2_k127_8541910_4 PFAM Uncharacterised protein family UPF0016 - - - 0.00000000000000000000000000000000000000000000000000001379 197.0
HFD2_k127_8541910_5 OpgC protein - - - 0.0000000000000000000000000000000000000000000009334 181.0
HFD2_k127_8541910_6 Belongs to the UPF0178 family K09768 - - 0.00000000000000000000000000000000000000005337 159.0
HFD2_k127_8541910_7 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.00000000000000000000000000000000000001353 151.0
HFD2_k127_8541910_8 - - - - 0.000000000009104 74.0
HFD2_k127_8541910_9 - - - - 0.000001756 53.0
HFD2_k127_8546670_0 Hydantoinaseoxoprolinase domain protein K01469,K01473 - 3.5.2.14,3.5.2.9 1.083e-265 840.0
HFD2_k127_8546670_1 PFAM Hydantoinase B oxoprolinase K01469,K01474 - 3.5.2.14,3.5.2.9 7.585e-209 665.0
HFD2_k127_8546670_2 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004322 392.0
HFD2_k127_8546670_3 PFAM Translin K07477 - - 0.000000000000000000000000000000000000000000000000000000000000005009 222.0
HFD2_k127_8546670_4 Domain of unknown function (DUF4346) K00577 - 2.1.1.86 0.0000000000000000000000000000000000000000000006399 178.0
HFD2_k127_8546670_5 - - - - 0.00000000000000007705 84.0
HFD2_k127_8546670_6 cellulose binding - - - 0.00000005028 64.0
HFD2_k127_8551042_0 PFAM glycosyl transferase, family 51 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006684 623.0
HFD2_k127_8555471_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007453 451.0
HFD2_k127_8555471_1 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000439 466.0
HFD2_k127_8555471_2 sequence-specific DNA binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009736 267.0
HFD2_k127_8555471_3 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000001145 194.0
HFD2_k127_8555471_4 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.00000000000000000000000000000000000000000000000009262 182.0
HFD2_k127_8555471_5 protein SCO1 SenC K07152 - - 0.000000000000007626 78.0
HFD2_k127_8565256_0 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005638 410.0
HFD2_k127_8565256_1 haloacid dehalogenase K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005947 285.0
HFD2_k127_8565256_2 LD-carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005681 261.0
HFD2_k127_8565256_3 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000001461 207.0
HFD2_k127_8565256_4 Phosphotriesterase family K07048 - - 0.0000000000000000000000000001141 121.0
HFD2_k127_8565256_5 Phosphotriesterase family K07048 - - 0.000000000000000001358 90.0
HFD2_k127_8565478_0 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 604.0
HFD2_k127_8565478_1 amino acid - - - 0.000000000000002003 84.0
HFD2_k127_8566328_0 amine dehydrogenase activity - - - 0.00000000000000000000000000000000146 146.0
HFD2_k127_8566328_1 Multicopper oxidase K00368,K07233,K22349 - 1.16.3.3,1.7.2.1 0.0000000000000000000000000000007416 141.0
HFD2_k127_8566328_2 Glycosyl transferase, family 2 - - - 0.00000000000000000006532 94.0
HFD2_k127_8566328_3 Uncharacterized membrane protein (DUF2298) - - - 0.00000000000000000008704 104.0
HFD2_k127_8568938_0 Protein export membrane protein K07239 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 551.0
HFD2_k127_8568938_1 TIGRFAM efflux transporter, RND family, MFP subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 312.0
HFD2_k127_8575515_0 Uncharacterized membrane protein (DUF2298) - - - 0.000000000000000000000000000000000000000000000000000000000002358 231.0
HFD2_k127_8575515_1 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000003392 84.0
HFD2_k127_8576669_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 2.733e-275 863.0
HFD2_k127_8576669_1 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.000000000000000000000000000000000000000000000000000000001101 205.0
HFD2_k127_8576669_2 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K02823 - - 0.00000000000000000000000000000000000000000000000001539 189.0
HFD2_k127_8591303_0 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 377.0
HFD2_k127_8591303_1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000002434 247.0
HFD2_k127_8591303_2 Formamidopyrimidine-DNA glycosylase H2TH domain - - - 0.00000000000000000000000000000000000000000000000000000000000000005632 231.0
HFD2_k127_8591303_3 Probable zinc-ribbon domain - - - 0.0000000000000000000000000000000007236 132.0
HFD2_k127_8591303_4 Predicted membrane protein (DUF2079) - - - 0.000000004998 69.0
HFD2_k127_8591303_5 Tetratricopeptide repeat - - - 0.0001436 51.0
HFD2_k127_8593919_0 HMGL-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 438.0
HFD2_k127_8593919_1 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000004614 154.0
HFD2_k127_8593919_2 - - - - 0.00000000000009817 75.0
HFD2_k127_8607438_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 313.0
HFD2_k127_8607438_1 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.0000000000000000000000000000000000000000429 157.0
HFD2_k127_8610113_0 Oxidoreductase family, C-terminal alpha/beta domain K13016 - 1.1.1.335 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 419.0
HFD2_k127_8610113_1 F420-dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004223 273.0
HFD2_k127_8610113_2 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000000000000000000000000000000000000000000000122 250.0
HFD2_k127_8610113_3 YbaK prolyl-tRNA synthetase associated region - - - 0.0000000000000000000000000000000000000000000000000000000001357 211.0
HFD2_k127_8610113_4 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000001435 205.0
HFD2_k127_8610113_5 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000004434 155.0
HFD2_k127_8620237_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 5.385e-231 727.0
HFD2_k127_8620237_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000005879 245.0
HFD2_k127_8620237_2 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000001611 212.0
HFD2_k127_8620237_3 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000000006546 150.0
HFD2_k127_8620237_5 Chagasin family peptidase inhibitor I42 - - - 0.0000000000003835 72.0
HFD2_k127_8632650_0 PFAM Cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 390.0
HFD2_k127_8632650_1 Acetyl xylan esterase (AXE1) K06889,K07397 - - 0.0000000000000000000000000000000000000000000000000000007441 198.0
HFD2_k127_8632650_2 PFAM 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000000000002434 130.0
HFD2_k127_8633770_0 Domain of unknown function (DUF4157) - - - 0.000000000000000000000008795 118.0
HFD2_k127_8633770_1 response regulator - - - 0.0000114 52.0
HFD2_k127_865269_0 Two component transcriptional regulator, winged helix family K07668 - - 0.000000000000000000000000000000000000000000000000000000000000000001584 235.0
HFD2_k127_865269_1 Histidine kinase K10681 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000003291 209.0
HFD2_k127_865269_2 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000001024 78.0
HFD2_k127_8657284_0 ABC transporter K06147,K18104 - 3.6.3.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004912 295.0
HFD2_k127_8657284_1 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.00005736 46.0
HFD2_k127_8662905_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 577.0
HFD2_k127_8662905_1 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009887 385.0
HFD2_k127_8662905_2 PFAM L-carnitine dehydratase bile acid-inducible protein F K18702 - 2.8.3.19 0.000000000000009765 80.0
HFD2_k127_8662905_3 PFAM DsrE family protein K07235 - - 0.00000009256 58.0
HFD2_k127_8662905_4 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0004181 48.0
HFD2_k127_8668842_0 PFAM ATPase associated with various cellular activities, AAA_3 K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 381.0
HFD2_k127_8668842_1 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000000000002054 204.0
HFD2_k127_8668842_2 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000267 173.0
HFD2_k127_8671596_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 2.818e-257 816.0
HFD2_k127_8671596_1 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006906 456.0
HFD2_k127_8671596_2 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 436.0
HFD2_k127_8671596_3 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 355.0
HFD2_k127_8671596_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007359 349.0
HFD2_k127_8671596_5 Two component transcriptional regulator, winged helix family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008113 272.0
HFD2_k127_8671596_6 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000001533 234.0
HFD2_k127_8671596_7 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000006841 110.0
HFD2_k127_8671596_8 - - - - 0.000003922 57.0
HFD2_k127_8671771_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K11473 - - 0.00000000000000000000000000000000000000725 149.0
HFD2_k127_8671771_1 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000002109 151.0
HFD2_k127_8672965_0 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001319 257.0
HFD2_k127_8672965_1 Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-non-specific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it decreases the phosphorylation status of KaiC. It has no effect on KaiC by itself, but instead needs the presence of both KaiA and KaiC, suggesting that it acts by antagonizing the interaction between KaiA and KaiC K08481 GO:0003674,GO:0005488,GO:0005515,GO:0007623,GO:0008150,GO:0009605,GO:0009649,GO:0009892,GO:0010563,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0042325,GO:0042326,GO:0042752,GO:0042802,GO:0045936,GO:0048511,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051174,GO:0065007 - 0.000000000000411 72.0
HFD2_k127_8678341_0 Phosphoenolpyruvate phosphomutase K03417 - 4.1.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 313.0
HFD2_k127_8678341_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0000000000000000000000000000000000000000000008055 173.0
HFD2_k127_8678341_2 inositol 2-dehydrogenase activity - - - 0.000000000000000000000002477 106.0
HFD2_k127_8679042_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 469.0
HFD2_k127_8679042_1 SAICAR synthetase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 340.0
HFD2_k127_8679042_2 PFAM imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000244 229.0
HFD2_k127_8679042_3 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.000000000000000000000000000000000000007648 160.0
HFD2_k127_8679042_4 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000005409 101.0
HFD2_k127_8679042_5 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000001663 100.0
HFD2_k127_8695618_0 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003686 422.0
HFD2_k127_8695618_1 Belongs to the peptidase S8 family - - - 0.0000000000002014 82.0
HFD2_k127_8701956_0 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 604.0
HFD2_k127_8701956_1 Cell division protein FtsA K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007019 425.0
HFD2_k127_8701956_2 UbiA prenyltransferase family K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 304.0
HFD2_k127_8701956_3 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000004841 210.0
HFD2_k127_8701956_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.000000000000000000000000000000003391 134.0
HFD2_k127_8701956_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000002388 129.0
HFD2_k127_8701956_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000281 64.0
HFD2_k127_8701956_7 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00001028 59.0
HFD2_k127_8704401_0 Acyltransferase - - - 0.0000000000000000006983 95.0
HFD2_k127_8704401_1 Peptidase dimerisation domain K01439 - 3.5.1.18 0.000000000000000075 84.0
HFD2_k127_8704401_2 PFAM transport-associated - - - 0.000000000008962 70.0
HFD2_k127_8709834_0 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000002499 215.0
HFD2_k127_8709834_1 PFAM ComEC Rec2-related protein K02238 - - 0.0000000000000000000000000000007838 139.0
HFD2_k127_8709834_2 DNA polymerase III delta subunit K02340 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.00000000000000000000009421 111.0
HFD2_k127_8709834_3 Polymer-forming cytoskeletal - - - 0.000000000000000000003835 102.0
HFD2_k127_8709834_4 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000002966 64.0
HFD2_k127_872016_0 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 339.0
HFD2_k127_872016_1 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 311.0
HFD2_k127_872016_2 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843,K02849 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001979 281.0
HFD2_k127_872016_3 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000000002191 201.0
HFD2_k127_872016_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000001479 177.0
HFD2_k127_872016_5 Type IV pilus biogenesis stability protein PilW - - - 0.000000000006417 70.0
HFD2_k127_872016_6 peptidyl-tyrosine sulfation - - - 0.000009252 51.0
HFD2_k127_8722417_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000007465 126.0
HFD2_k127_8722417_1 Protein conserved in bacteria - - - 0.0000000000000000000000000001674 119.0
HFD2_k127_8727306_0 Receptor family ligand binding region K11959 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005094 582.0
HFD2_k127_8727306_1 Belongs to the binding-protein-dependent transport system permease family K01997,K11960 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 385.0
HFD2_k127_8727306_10 Higher Eukarytoes and Prokaryotes Nucleotide-binding domain - - - 0.000000000000000000000000002618 116.0
HFD2_k127_8727306_11 PFAM DNA polymerase beta domain protein region - - - 0.00000000478 62.0
HFD2_k127_8727306_2 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 378.0
HFD2_k127_8727306_3 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 331.0
HFD2_k127_8727306_4 Branched-chain amino acid ATP-binding cassette transporter K11962 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 286.0
HFD2_k127_8727306_5 Belongs to the N(4) N(6)-methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000003071 226.0
HFD2_k127_8727306_6 PFAM ABC transporter K01996,K11963 - - 0.000000000000000000000000000000000000000000000000000003944 195.0
HFD2_k127_8727306_7 Glycosyl transferase family 2 K12992 - - 0.00000000000000000000000000000000000000000000000001022 189.0
HFD2_k127_8727306_8 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000002494 195.0
HFD2_k127_8727306_9 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000006458 167.0
HFD2_k127_8748600_0 Type III restriction enzyme, res subunit - - - 9.91e-302 956.0
HFD2_k127_8748600_1 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000009501 182.0
HFD2_k127_8748600_2 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000002788 164.0
HFD2_k127_8748600_3 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000004367 175.0
HFD2_k127_8748600_4 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000000000000000000000000000003337 153.0
HFD2_k127_8748600_5 Thioesterase-like superfamily K02614 - - 0.0000000000000000000000000000000000003434 145.0
HFD2_k127_8748600_6 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000000000000000000000002758 145.0
HFD2_k127_8748600_7 Chromate transporter K07240 - - 0.00000001146 64.0
HFD2_k127_8751584_0 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001104 266.0
HFD2_k127_8751584_1 Domain of unknown function (DUF4129) - - - 0.000000000000000001499 100.0
HFD2_k127_8751584_2 Bacterial extracellular solute-binding protein K02027 - - 0.000000382 52.0
HFD2_k127_881631_0 E1-E2 ATPase K17686 - 3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 308.0
HFD2_k127_881631_1 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000001723 132.0
HFD2_k127_890323_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000409 518.0
HFD2_k127_890323_1 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005213 347.0
HFD2_k127_890323_2 Aldo/keto reductase family K18471 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002204 265.0
HFD2_k127_890323_3 serine threonine protein kinase - - - 0.00000000000000000000000000000000000004177 147.0
HFD2_k127_894006_0 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000001585 199.0
HFD2_k127_894006_1 SNARE associated Golgi protein K19302 - 3.6.1.27 0.00000000000000006846 91.0
HFD2_k127_89459_0 beta-1,4-mannooligosaccharide phosphorylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007544 460.0
HFD2_k127_89459_1 GMC oxidoreductase K06151 - 1.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 446.0
HFD2_k127_89459_2 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 328.0
HFD2_k127_89459_3 Highly conserved protein containing a thioredoxin domain K02027 - - 0.00000000000000000000000000000000000000000000000000000000000001086 230.0
HFD2_k127_89459_4 Gluconate 2-dehydrogenase subunit 3 K06152 - 1.1.99.3 0.00000000000000000000001374 107.0
HFD2_k127_89459_5 Cupin 2, conserved barrel domain protein - - - 0.000000000000001379 80.0
HFD2_k127_89459_6 Putative restriction endonuclease - - - 0.00000000000001464 76.0
HFD2_k127_904278_0 Calcineurin-like phosphoesterase K01077 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 348.0
HFD2_k127_904278_1 Glycosyl transferase, family 2 K00786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.0000000000000000001645 99.0
HFD2_k127_904278_2 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000002209 62.0
HFD2_k127_908240_0 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic K02051 - - 0.000000000000000000000000000000000000000000151 171.0
HFD2_k127_908240_1 NMT1-like family K02051 - - 0.000000000000000000000000000000002811 136.0
HFD2_k127_908360_0 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 351.0
HFD2_k127_908360_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000001038 132.0
HFD2_k127_908360_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000002717 67.0
HFD2_k127_908360_3 Lipase (class 2) K01046 - 3.1.1.3 0.000001057 60.0
HFD2_k127_908360_4 COG0444 ABC-type dipeptide oligopeptide nickel transport system, ATPase component K02031 - - 0.0004131 46.0
HFD2_k127_911732_0 His Kinase A (phosphoacceptor) domain K02484,K07636,K07768 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006807 457.0
HFD2_k127_911732_1 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000004722 128.0
HFD2_k127_912335_0 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004756 578.0
HFD2_k127_912335_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 393.0
HFD2_k127_912335_2 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000007242 190.0
HFD2_k127_913931_0 Cobalamin-independent synthase, Catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007255 408.0
HFD2_k127_913931_1 PFAM alpha beta hydrolase fold K01561 - 3.8.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 392.0
HFD2_k127_913931_2 MFS_1 like family - - - 0.00000000000000000000000000000000000000000000000001604 195.0
HFD2_k127_913931_3 Cobalamin-independent synthase, Catalytic domain - - - 0.0000000003937 61.0
HFD2_k127_920334_0 4-hydroxyphenylacetate 3-hydroxylase C terminal - - - 2.251e-197 623.0
HFD2_k127_920334_1 mismatched DNA binding K03555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 493.0
HFD2_k127_920334_2 protein conserved in cyanobacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000003655 228.0
HFD2_k127_920778_0 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004441 297.0
HFD2_k127_920778_1 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000009666 224.0
HFD2_k127_920778_2 PFAM Extracellular solute-binding protein, family 3 K02030 - - 0.00000000000000008009 87.0
HFD2_k127_928893_0 LUD domain K00782,K18929 - - 2.314e-201 649.0
HFD2_k127_928893_1 LUD domain K00782 - - 0.0000000000004616 77.0
HFD2_k127_931965_0 TIGRFAM LPPG domain protein containing protein K11212 - 2.7.8.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 353.0
HFD2_k127_931965_1 FIST C domain - GO:0008150,GO:0040007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000002551 255.0
HFD2_k127_932013_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 370.0
HFD2_k127_932013_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000002194 168.0
HFD2_k127_938586_0 - - - - 0.0000000000000000000000000000000000005209 146.0
HFD2_k127_938586_1 FR47-like protein - - - 0.00007059 52.0
HFD2_k127_94341_0 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009025 284.0
HFD2_k127_94341_1 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002983 265.0
HFD2_k127_94341_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000918 203.0
HFD2_k127_94341_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000001589 159.0
HFD2_k127_94341_4 Nitroreductase family - - - 0.000000000000000001419 88.0
HFD2_k127_943907_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 431.0
HFD2_k127_958553_0 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 310.0
HFD2_k127_958553_1 membrane protein, required for N-linked glycosylation K07151 GO:0003674,GO:0003824,GO:0008150,GO:0009987,GO:0016043,GO:0016740,GO:0016757,GO:0045229,GO:0045232,GO:0071840 2.4.99.18 0.0001278 54.0
HFD2_k127_963537_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006494 428.0
HFD2_k127_963537_1 response regulator, receiver K02483,K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003668 334.0
HFD2_k127_963537_2 Domain of unknown function (DUF4118) K07646 - 2.7.13.3 0.00000000000000000000000000000005789 127.0
HFD2_k127_97583_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 424.0
HFD2_k127_97583_1 PFAM phosphate transporter K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004288 362.0
HFD2_k127_97583_2 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005488 296.0
HFD2_k127_97583_3 Glycosyl hydrolase family 76 - - - 0.0000000000000000000000000000000000000000000229 177.0
HFD2_k127_97583_4 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000004862 120.0
HFD2_k127_977336_0 ribonuclease activity - - - 0.0000000000000000000000000000008624 128.0
HFD2_k127_977336_1 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.00000000000000000000000005085 114.0
HFD2_k127_977336_2 quinone binding K00368 - 1.7.2.1 0.00000000000000000000005964 104.0
HFD2_k127_977336_3 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.00000000000000000001221 94.0
HFD2_k127_978843_0 Binding-protein-dependent transport system inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 587.0
HFD2_k127_978843_1 Dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 358.0
HFD2_k127_978843_10 Zinc-binding dehydrogenase K18382 - - 0.0000002742 54.0
HFD2_k127_978843_11 Type III restriction enzyme res subunit - - - 0.0001242 53.0
HFD2_k127_978843_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K02052 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007733 352.0
HFD2_k127_978843_3 Bacterial extracellular solute-binding protein K02012,K02055 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000081 321.0
HFD2_k127_978843_4 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03169 - 5.99.1.2 0.00000000000000000000005321 109.0
HFD2_k127_978843_5 COG0604 NADPH quinone reductase and related Zn-dependent - - - 0.000000000000000003286 90.0
HFD2_k127_978843_6 Zinc-binding dehydrogenase - - - 0.00000000000000001761 89.0
HFD2_k127_978843_7 Putative transposase of IS4/5 family (DUF4096) - - - 0.000000000000003097 85.0
HFD2_k127_978843_8 Transposase and inactivated derivatives - - - 0.0000000000002194 72.0
HFD2_k127_978843_9 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.000000002142 59.0
HFD2_k127_999416_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07239 - - 1.032e-300 942.0
HFD2_k127_999894_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 325.0
HFD2_k127_999894_1 - - - - 0.000000000002695 69.0