Overview

ID MAG01663
Name HFD2_bin.55
Sample SMP0044
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Alphaproteobacteria
Order Caulobacterales
Family TH1-2
Genus Vitreimonas
Species
Assembly information
Completeness (%) 68.47
Contamination (%) 2.64
GC content (%) 63.0
N50 (bp) 8,647
Genome size (bp) 2,544,929

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2633

Gene name Description KEGG GOs EC E-value Score Sequence
HFD2_k127_100715_0 due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1184.0
HFD2_k127_100715_1 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.0 1028.0
HFD2_k127_100715_10 - - - - 0.000000001591 65.0
HFD2_k127_100715_2 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 379.0
HFD2_k127_100715_4 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001359 273.0
HFD2_k127_100715_5 Domain of unknown function (DUF3576) - - - 0.0000000000000000000000000000000000000000000008635 174.0
HFD2_k127_100715_6 Thiamine monophosphate synthase K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000002719 171.0
HFD2_k127_100715_7 DNA polymerase III K02340 - 2.7.7.7 0.00000000000000000008156 98.0
HFD2_k127_100715_8 Lipopolysaccharide-assembly K03643 - - 0.00000000000000001485 89.0
HFD2_k127_100715_9 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.00000000000001661 79.0
HFD2_k127_1020677_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.00000000000000000000000000000000000000000000000002533 183.0
HFD2_k127_1020677_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000003519 143.0
HFD2_k127_1020677_2 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000002579 120.0
HFD2_k127_1020677_3 CAAX protease self-immunity K07052 - - 0.00000000000000000000005717 110.0
HFD2_k127_1025248_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1112.0
HFD2_k127_1025248_1 Dehydrogenase E1 component K00162,K11381 - 1.2.4.1,1.2.4.4 0.0 1028.0
HFD2_k127_1025248_10 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007115 566.0
HFD2_k127_1025248_11 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 389.0
HFD2_k127_1025248_12 Flavin containing amine oxidoreductase K00274 - 1.4.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 378.0
HFD2_k127_1025248_13 AAA domain K07028 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 346.0
HFD2_k127_1025248_14 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 318.0
HFD2_k127_1025248_15 Belongs to the ribose-phosphate pyrophosphokinase family K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004912 308.0
HFD2_k127_1025248_16 Helix-hairpin-helix domain K04477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005023 308.0
HFD2_k127_1025248_17 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009793 314.0
HFD2_k127_1025248_18 Efflux transporter, RND family, MFP subunit K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001404 289.0
HFD2_k127_1025248_19 Belongs to the carbohydrate kinase PfkB family K16370 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003097 274.0
HFD2_k127_1025248_2 ATPase, P-type transporting, HAD superfamily, subfamily IC K01537 - 3.6.3.8 1.207e-319 1001.0
HFD2_k127_1025248_20 COG1956 GAF domain-containing protein K08968 - 1.8.4.14 0.00000000000000000000000000000000000000000000000000000000000000000001528 236.0
HFD2_k127_1025248_21 Phosphoribosyl transferase domain K07100 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000001352 234.0
HFD2_k127_1025248_22 Phosphoribosyl transferase domain K07100 - - 0.000000000000000000000000000000000000000000000000000000000006398 214.0
HFD2_k127_1025248_23 bacterial OsmY and nodulation domain K04065 - - 0.000000000000000000000000000000000000000000000000000003628 199.0
HFD2_k127_1025248_24 - - - - 0.00000000000000000000000000000000000000000000000001867 186.0
HFD2_k127_1025248_25 Universal stress protein - - - 0.00000000000000000000000000000000000000000001293 173.0
HFD2_k127_1025248_26 Protein of unknown function (DUF541) K09807 - - 0.00000000000000000000000000000000000000000004659 173.0
HFD2_k127_1025248_27 NUDIX domain - - - 0.00000000000000000000000000000000000000000008161 166.0
HFD2_k127_1025248_28 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000739 166.0
HFD2_k127_1025248_29 ABC-type transport system, permease components - - - 0.000000000000000000000000000000000000004466 153.0
HFD2_k127_1025248_3 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895,K01907 - 6.2.1.1,6.2.1.16 9.235e-265 827.0
HFD2_k127_1025248_30 Universal stress protein UspA - - - 0.000000000000000000000000000000000000004522 157.0
HFD2_k127_1025248_31 - - - - 0.00000000000000000000000000000000000003636 148.0
HFD2_k127_1025248_32 Ion channel - - - 0.0000000000000000000000000000000000001229 147.0
HFD2_k127_1025248_33 Universal stress protein family - - - 0.0000000000000000000000000000000000001444 153.0
HFD2_k127_1025248_34 - - - - 0.0000000000000000000000000000000000005436 144.0
HFD2_k127_1025248_35 Hsp20/alpha crystallin family K13993 - - 0.0000000000000000000000000000000000008317 144.0
HFD2_k127_1025248_36 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.00000000000000000000000000000000000598 149.0
HFD2_k127_1025248_37 F420H(2)-dependent quinone reductase - - - 0.0000000000000000000000000000004611 130.0
HFD2_k127_1025248_38 Uncharacterized conserved protein (DUF2267) - - - 0.0000000000000000000000000000005625 126.0
HFD2_k127_1025248_4 PFAM peptidase M14 carboxypeptidase A - - - 3.999e-205 655.0
HFD2_k127_1025248_40 Phosphopantetheine attachment site - - - 0.0000000000000000000001496 98.0
HFD2_k127_1025248_41 - - - - 0.000000000000000001291 95.0
HFD2_k127_1025248_42 Belongs to the UPF0337 (CsbD) family - - - 0.000000000009485 69.0
HFD2_k127_1025248_43 CHAT domain - - - 0.0000009123 60.0
HFD2_k127_1025248_45 LTXXQ motif family protein - - - 0.00002305 53.0
HFD2_k127_1025248_46 Protein of unknown function (DUF5132) - - - 0.00004465 50.0
HFD2_k127_1025248_47 - - - - 0.0004252 49.0
HFD2_k127_1025248_5 Cation transport ATPase (P-type) K01537 - 3.6.3.8 1.377e-204 670.0
HFD2_k127_1025248_6 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00758 - 2.4.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007837 605.0
HFD2_k127_1025248_7 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 583.0
HFD2_k127_1025248_8 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 586.0
HFD2_k127_1025248_9 Belongs to the CarA family K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006405 558.0
HFD2_k127_1033986_0 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 300.0
HFD2_k127_1033986_1 Secretion protein K01993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004143 278.0
HFD2_k127_1040466_0 Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate K06447 - 1.2.1.71 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008933 534.0
HFD2_k127_1040466_1 Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) K01484 - 3.5.3.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 486.0
HFD2_k127_1040466_2 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases K01295 - 3.4.17.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008104 442.0
HFD2_k127_1040466_3 COG3138 Arginine ornithine N-succinyltransferase beta subunit K00673 - 2.3.1.109 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 348.0
HFD2_k127_1040466_4 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004316 259.0
HFD2_k127_1040466_5 hemimethylated DNA binding K11940 - - 0.000000000000000000000000000000000000000000005026 168.0
HFD2_k127_1069688_0 cytochrome c biogenesis protein K04084 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005165 549.0
HFD2_k127_1069688_1 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008178 477.0
HFD2_k127_1069688_2 SapC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001681 250.0
HFD2_k127_1069688_3 ligase activity - - - 0.000000000000000000000002759 107.0
HFD2_k127_1070288_0 Helicase K03724 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007093 481.0
HFD2_k127_1070288_1 Calcineurin-like phosphoesterase K06953 - - 0.000000000000000000000000000000000000000000000000000000000000000000001273 246.0
HFD2_k127_1070288_2 Putative transmembrane protein (Alph_Pro_TM) - - - 0.000000000000000000000003781 108.0
HFD2_k127_1070288_3 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K06191 - - 0.000000005217 64.0
HFD2_k127_1112637_0 exodeoxyribonuclease III K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005963 315.0
HFD2_k127_1112637_1 SMART PAS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000002013 215.0
HFD2_k127_1112637_2 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000002614 173.0
HFD2_k127_1112637_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000008798 151.0
HFD2_k127_1112637_4 - - - - 0.00000000000000000000000000000001264 136.0
HFD2_k127_1112637_5 Ftsk_gamma K03466 - - 0.00000000000000003348 81.0
HFD2_k127_1114076_0 Epoxide hydrolase N terminus K01253 - 3.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 569.0
HFD2_k127_1131759_0 Ferritin-like K20087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 614.0
HFD2_k127_1131759_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008389 516.0
HFD2_k127_1131759_2 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0044424,GO:0044464,GO:0140096 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004462 270.0
HFD2_k127_1131759_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000003046 242.0
HFD2_k127_1131759_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 GO:0003674,GO:0005215 - 0.0000000000000000001826 93.0
HFD2_k127_1139820_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000108 168.0
HFD2_k127_1139820_1 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.000000000000000000000000000000006268 132.0
HFD2_k127_1139820_2 Protein of unknown function (DUF1109) - - - 0.000000000000000000000000001323 123.0
HFD2_k127_1143470_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009902 529.0
HFD2_k127_1143470_1 NAD(P)H-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 505.0
HFD2_k127_1143470_10 Inositol monophosphatase K01092,K18649 - 3.1.3.15,3.1.3.25,3.1.3.93 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001021 282.0
HFD2_k127_1143470_11 alpha beta fold family K01048 - 3.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000004717 265.0
HFD2_k127_1143470_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000000615 228.0
HFD2_k127_1143470_13 NIPSNAP - - - 0.00000000000000000000000000000000000000000000000000000000001245 216.0
HFD2_k127_1143470_14 transcriptional - - - 0.0000000000000000000000000000000000000000000000004171 179.0
HFD2_k127_1143470_15 COG0346 Lactoylglutathione lyase and related lyases - - - 0.0000000000000000000000000000000000000000000000007484 177.0
HFD2_k127_1143470_16 Hsp20/alpha crystallin family K04080 - - 0.000000000000000000000000000000000000000000005707 171.0
HFD2_k127_1143470_17 YCII-related domain - - - 0.0000000000000000000000000000000007559 134.0
HFD2_k127_1143470_18 PFAM Sterol-binding domain protein - - - 0.00000000000000000000000000427 113.0
HFD2_k127_1143470_19 'PFAM Response regulator receiver - - - 0.00000000000000000000000003026 113.0
HFD2_k127_1143470_2 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007435 448.0
HFD2_k127_1143470_20 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000000001878 108.0
HFD2_k127_1143470_21 YCII-related domain - - - 0.000000000000000000000009157 104.0
HFD2_k127_1143470_22 - - - - 0.00000000000000000005391 94.0
HFD2_k127_1143470_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007464 441.0
HFD2_k127_1143470_4 RNA polymerase sigma factor containing a TPR repeat domain K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 413.0
HFD2_k127_1143470_5 WYL domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008314 337.0
HFD2_k127_1143470_6 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 325.0
HFD2_k127_1143470_7 COG0625 Glutathione S-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004462 314.0
HFD2_k127_1143470_8 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 293.0
HFD2_k127_1143470_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000722 295.0
HFD2_k127_1152855_0 poly(R)-hydroxyalkanoic acid synthase K03821 - - 1.241e-232 737.0
HFD2_k127_1152855_1 COG0076 Glutamate decarboxylase and related PLP-dependent proteins K01634 - 4.1.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009719 536.0
HFD2_k127_1152855_2 fructose-1,6-bisphosphatase K11532 - 3.1.3.11,3.1.3.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004058 434.0
HFD2_k127_1152855_3 Exonuclease RecJ K07462 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008297,GO:0008409,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0035312,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0045145,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 336.0
HFD2_k127_1152855_4 Exonuclease RecJ K07462 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008297,GO:0008409,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0035312,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0045145,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000001985 262.0
HFD2_k127_1152855_5 Belongs to the peptidase S11 family K01286,K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000005369 212.0
HFD2_k127_1152855_6 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000001536 174.0
HFD2_k127_1152855_7 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000000000000000000000474 151.0
HFD2_k127_1152855_8 - - - - 0.000000001421 70.0
HFD2_k127_1166481_0 Peptidase S9 prolyl oligopeptidase active site - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009902 599.0
HFD2_k127_1166481_1 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006794 583.0
HFD2_k127_1166481_2 Glycosyl transferase family group 2 - - - 0.000000000000000000000002423 111.0
HFD2_k127_1166481_3 Tetratricopeptide repeat - - - 0.000000000000000000000004775 111.0
HFD2_k127_1176719_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.15 9.437e-240 750.0
HFD2_k127_1176719_1 beta-lactamase K12574 - - 1.964e-223 705.0
HFD2_k127_1176719_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004076 419.0
HFD2_k127_1176719_3 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009588 375.0
HFD2_k127_1176719_4 NADH ubiquinone oxidoreductase K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 314.0
HFD2_k127_1176719_5 methylmalonyl-CoA epimerase K05606 - 5.1.99.1 0.0000000000000000000000000000000000000000000000000000000000005455 214.0
HFD2_k127_1176719_6 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.000000000000000000000000000000000000000000000000000000004788 208.0
HFD2_k127_1176719_7 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000001693 205.0
HFD2_k127_1176719_8 Protein of unknown function (DUF1467) - - - 0.000000001123 62.0
HFD2_k127_1187770_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 3.665e-284 880.0
HFD2_k127_1187770_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 575.0
HFD2_k127_1187770_11 Preprotein translocase SecG subunit K03075 - - 0.0000000000000002199 88.0
HFD2_k127_1187770_12 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000003735 58.0
HFD2_k127_1187770_14 Competence protein K02238 - - 0.00002307 55.0
HFD2_k127_1187770_15 - - - - 0.0000872 50.0
HFD2_k127_1187770_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004166 522.0
HFD2_k127_1187770_3 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 320.0
HFD2_k127_1187770_4 Belongs to the TrpC family K01609 - 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004171 316.0
HFD2_k127_1187770_5 Anthranilate synthase K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002285 301.0
HFD2_k127_1187770_6 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000327 286.0
HFD2_k127_1187770_7 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000001929 249.0
HFD2_k127_1187770_8 aminotransferase class V - - - 0.000000000000000000000000000000000000000000000000000000000000000002377 229.0
HFD2_k127_1187770_9 SurA N-terminal domain K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000002726 202.0
HFD2_k127_1262132_0 Adenylate cyclase - - - 6.104e-211 667.0
HFD2_k127_1262132_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 510.0
HFD2_k127_1262132_2 methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 288.0
HFD2_k127_1262132_3 Belongs to the GST superfamily K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000002464 241.0
HFD2_k127_1262132_4 SPFH domain / Band 7 family - - - 0.00000000000000000000000000000000000000006118 154.0
HFD2_k127_1262132_5 Tautomerase enzyme K01821 - 5.3.2.6 0.00000000000000000000000000000002085 126.0
HFD2_k127_1262132_6 Plasmid stabilization - - - 0.0000000000000000000000000000001227 130.0
HFD2_k127_1262132_7 - - - - 0.00000000000000000000002278 109.0
HFD2_k127_1313038_0 M13 family peptidase K01415,K07386 - 3.4.24.71 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 477.0
HFD2_k127_1313038_1 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 366.0
HFD2_k127_1313038_2 Uracil DNA glycosylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002954 254.0
HFD2_k127_1313038_3 - - - - 0.000000000000000000001334 106.0
HFD2_k127_1344991_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001944 261.0
HFD2_k127_1404546_0 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2 K00162 - 1.2.4.1 2.367e-217 689.0
HFD2_k127_1404546_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 6.696e-206 647.0
HFD2_k127_1404546_10 MAPEG family - - - 0.000000000000007401 79.0
HFD2_k127_1404546_11 Septum formation initiator - - - 0.000001307 54.0
HFD2_k127_1404546_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000541 519.0
HFD2_k127_1404546_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004382 505.0
HFD2_k127_1404546_4 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000000000319 182.0
HFD2_k127_1404546_5 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000009862 175.0
HFD2_k127_1404546_6 Diacylglycerol kinase catalytic - - - 0.0000000000000000000000000000000000000000003332 174.0
HFD2_k127_1404546_7 Protein of unknown function (DUF3775) - - - 0.00000000000000000000000000002512 125.0
HFD2_k127_1404546_8 Glutathione-dependent formaldehyde-activating - - - 0.000000000000000000000001949 108.0
HFD2_k127_1404546_9 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000000000000008576 106.0
HFD2_k127_143495_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 411.0
HFD2_k127_143495_1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 330.0
HFD2_k127_143495_2 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000005197 182.0
HFD2_k127_1435308_0 - - - - 0.0000000000003984 81.0
HFD2_k127_1435308_1 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000004846 75.0
HFD2_k127_1456102_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 1.308e-218 692.0
HFD2_k127_1456102_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 588.0
HFD2_k127_1456102_2 N-terminal domain of oxidoreductase K07119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 401.0
HFD2_k127_1456102_3 Precorrin-8x methylmutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 381.0
HFD2_k127_1456102_4 MATE efflux family protein K03327 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008896 289.0
HFD2_k127_1456102_5 Nickel/cobalt transporter regulator - - - 0.0000000000000000000000000000000002862 139.0
HFD2_k127_1491056_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004644 499.0
HFD2_k127_1491056_1 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000007004 250.0
HFD2_k127_1491056_2 Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000003465 215.0
HFD2_k127_1491056_3 - - - - 0.000000000000000000000000000000000000000000000000000000000003992 217.0
HFD2_k127_1491056_4 - - - - 0.00000000000000000000001967 101.0
HFD2_k127_1491056_5 - - - - 0.0000000003377 67.0
HFD2_k127_1491056_6 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.000000005574 58.0
HFD2_k127_1524026_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.707e-238 745.0
HFD2_k127_1524026_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000007873 120.0
HFD2_k127_1524026_3 - - - - 0.00009971 50.0
HFD2_k127_1533086_0 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 391.0
HFD2_k127_1533086_1 phosphoserine phosphatase K01079 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 313.0
HFD2_k127_1533086_2 HflC and HflK could encode or regulate a protease K04088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001399 290.0
HFD2_k127_1533086_3 HflC and HflK could regulate a protease K04087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002426 261.0
HFD2_k127_1533086_4 subfamily IA, variant 3 - - - 0.0000000000000000000000000000000000000000000000001681 186.0
HFD2_k127_1590042_0 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 1.96e-303 938.0
HFD2_k127_1590042_1 aminopeptidase K01256 - 3.4.11.2 1.876e-213 693.0
HFD2_k127_1590042_2 Belongs to the FPP GGPP synthase family K00795 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009536,GO:0009842,GO:0009987,GO:0016114,GO:0016740,GO:0016765,GO:0019637,GO:0033385,GO:0033386,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0090407,GO:1901576 2.5.1.1,2.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 338.0
HFD2_k127_1590042_3 Including yeast histone deacetylase and acetoin utilization protein K04768 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 337.0
HFD2_k127_1590042_4 enoyl-CoA delta isomerase 2 K13239,K17964 GO:0003674,GO:0003824,GO:0004165,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006950,GO:0006952,GO:0008150,GO:0009605,GO:0009607,GO:0009617,GO:0016853,GO:0016860,GO:0016863,GO:0042579,GO:0042742,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0050829,GO:0050896,GO:0051704,GO:0051707,GO:0098542 5.3.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000002709 265.0
HFD2_k127_1590042_5 Histidine phosphatase superfamily (branch 1) - - - 0.0000000000000000000000000000000000000000000000000000000001807 214.0
HFD2_k127_1590042_6 Putative tRNA binding domain K06878 GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0017101,GO:0017102,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000181 150.0
HFD2_k127_1590042_7 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000000000001764 94.0
HFD2_k127_1590042_8 Domain of unknown function (DUF4337) - - - 0.000004765 50.0
HFD2_k127_1590042_9 TIR domain - - - 0.00000922 57.0
HFD2_k127_1593284_0 Participates in both transcription termination and antitermination K02600 - - 1.372e-227 717.0
HFD2_k127_1593284_1 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000005387 178.0
HFD2_k127_1593284_2 Protein of unknown function (DUF448) K07742 - - 0.000000000000000000000000000000000000313 147.0
HFD2_k127_1593284_3 - - - - 0.0000000000000000000000000000000000005405 147.0
HFD2_k127_1593284_4 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.000000002441 58.0
HFD2_k127_1593963_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 0.0 1015.0
HFD2_k127_1593963_1 COG0665 Glycine D-amino acid oxidases (deaminating) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 366.0
HFD2_k127_1593963_2 cation diffusion facilitator family transporter K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 317.0
HFD2_k127_1593963_3 Belongs to the Nudix hydrolase family K03426 - 3.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 292.0
HFD2_k127_1593963_4 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000179 212.0
HFD2_k127_1593963_5 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000001124 175.0
HFD2_k127_1593963_6 aspartic-type endopeptidase activity - - - 0.00000000000000000000000000000000001109 150.0
HFD2_k127_1593963_7 - - - - 0.0000000000000000003453 93.0
HFD2_k127_1596779_0 Bacterial protein of unknown function (DUF853) K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009312 494.0
HFD2_k127_1596779_1 COG2902 NAD-specific glutamate dehydrogenase K15371 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0008150,GO:0008152,GO:0016491,GO:0016638,GO:0016639,GO:0055114 1.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007397 345.0
HFD2_k127_1596779_2 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 336.0
HFD2_k127_160396_0 AlkA N-terminal domain K13529 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 421.0
HFD2_k127_160396_1 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000000000000000000000000000001613 186.0
HFD2_k127_160396_2 Antibiotic biosynthesis monooxygenase K11530 - 5.3.1.32 0.000000001023 64.0
HFD2_k127_160396_3 ISXO2-like transposase domain - - - 0.0006651 43.0
HFD2_k127_1617769_0 asparagine synthase K01953 - 6.3.5.4 2.807e-242 763.0
HFD2_k127_1617769_1 Glycosyl transferase family 2 K00721,K10012 - 2.4.1.83,2.4.2.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005122 424.0
HFD2_k127_1617769_2 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006171 319.0
HFD2_k127_1617769_3 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000000000000000000000001042 201.0
HFD2_k127_1617769_4 COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000001854 141.0
HFD2_k127_1617769_5 Protein of unknown function (DUF3108) - - - 0.000000000000000001836 95.0
HFD2_k127_1617769_6 Resolvase, N terminal domain - - - 0.0000000000000009243 79.0
HFD2_k127_1617769_7 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000001737 77.0
HFD2_k127_1617960_0 propionyl-CoA carboxylase beta - - - 1.674e-273 849.0
HFD2_k127_1617960_1 PFAM Acetyltransferase (GNAT) family K03828 - - 0.000000000000000000000000000000000000000000000000000268 188.0
HFD2_k127_1617960_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.00000000000002182 79.0
HFD2_k127_1617960_3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000002953 73.0
HFD2_k127_1617960_4 - - - - 0.000005539 52.0
HFD2_k127_1639980_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 556.0
HFD2_k127_1639980_1 Inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004493 361.0
HFD2_k127_1639980_2 MFS/sugar transport protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002071 264.0
HFD2_k127_1639980_3 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000005906 226.0
HFD2_k127_1639980_4 protein conserved in bacteria containing a divergent form of TPR repeats - - - 0.000000000000000000000000000000000000000000000000000000000000004841 224.0
HFD2_k127_1639980_5 Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 K15461 - 2.1.1.61 0.000000000000000000000000000000000000000001447 169.0
HFD2_k127_1639980_6 gag-polyprotein putative aspartyl protease - - - 0.000000000000000000000000000000000001786 152.0
HFD2_k127_1639980_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000001194 139.0
HFD2_k127_1675474_0 Aldehyde dehydrogenase K00128,K19700 - 1.2.1.3,1.2.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 570.0
HFD2_k127_1675474_1 COG0626 Cystathionine beta-lyases cystathionine gamma-synthases K01739,K01761 - 2.5.1.48,4.4.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004438 521.0
HFD2_k127_1675474_2 Helicase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 394.0
HFD2_k127_1675474_3 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.000000000000000000000000000000000000000000000000000000000000000000003792 241.0
HFD2_k127_1675474_4 Cytochrome c - - - 0.0000000000000002661 83.0
HFD2_k127_1679522_0 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 473.0
HFD2_k127_1679522_1 Short branched chain specific acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000008733 195.0
HFD2_k127_1679522_2 Lytic transglycosylase - - - 0.0000000000000000000000000000000000000000000002029 178.0
HFD2_k127_1679522_3 PepSY-associated TM region - - - 0.000000000000000000000000000000000000002493 155.0
HFD2_k127_1699816_0 Aminoglycoside phosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 538.0
HFD2_k127_1699816_1 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 498.0
HFD2_k127_1699816_2 PFAM Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 448.0
HFD2_k127_1699816_3 O-methyltransferase K00598 - 2.1.1.144 0.000000000000000000000000000000000000000000000000000000000000000000000000005312 263.0
HFD2_k127_1699816_4 leukotriene A-4 hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001273 254.0
HFD2_k127_1699816_5 PFAM Mg2 transporter protein CorA family protein K03284 - - 0.000000000000000000001255 101.0
HFD2_k127_1699816_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000963 57.0
HFD2_k127_1705873_0 NADH-quinone oxidoreductase K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 348.0
HFD2_k127_1705873_1 - - - - 0.00000000000000000000000008267 111.0
HFD2_k127_1720545_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.08e-276 860.0
HFD2_k127_1720545_1 Modulator of DNA gyrase K03568 - - 1.861e-202 646.0
HFD2_k127_1720545_2 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000003776 260.0
HFD2_k127_1720545_3 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000001394 206.0
HFD2_k127_1720545_4 Tetratricopeptide repeat - - - 0.000000000000000000000000004375 121.0
HFD2_k127_1720545_5 Tetratricopeptide repeat - - - 0.000000000000002805 82.0
HFD2_k127_1720794_0 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000004003 161.0
HFD2_k127_1720794_1 Diacylglycerol kinase K00901 - 2.7.1.107 0.0000000000000000000000000000000000000003716 151.0
HFD2_k127_1720794_2 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.0000000000000000000000000000008862 123.0
HFD2_k127_1738300_0 Tyrosine kinase - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004426 581.0
HFD2_k127_1738300_1 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000006662 170.0
HFD2_k127_1738300_2 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.000002359 57.0
HFD2_k127_1738300_3 EF-hand, calcium binding motif - - - 0.000008044 52.0
HFD2_k127_1749398_0 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004869 372.0
HFD2_k127_1749398_1 COG1192 ATPases involved in chromosome partitioning K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007804 363.0
HFD2_k127_1749398_2 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008568 339.0
HFD2_k127_1749398_3 Belongs to the peptidase S11 family K01286,K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008512 277.0
HFD2_k127_1749398_4 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.00000000003892 69.0
HFD2_k127_1749398_5 DnaJ molecular chaperone homology domain - - - 0.000000009193 62.0
HFD2_k127_1756695_0 Putative 2OG-Fe(II) oxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 321.0
HFD2_k127_1756695_1 Putative 2OG-Fe(II) oxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000003611 249.0
HFD2_k127_1756695_2 ATP12 chaperone protein - - - 0.000000000000000000000000000000000000000000000000006239 189.0
HFD2_k127_1756695_3 Belongs to the pseudouridine synthase RluA family K06179 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.24 0.0000000000000000001528 90.0
HFD2_k127_1756752_0 Peptidase family M28 - - - 7.42e-211 664.0
HFD2_k127_1756752_1 PFAM glycosyl transferase family 28 K05841 - 2.4.1.173 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007864 509.0
HFD2_k127_1756752_2 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000004989 219.0
HFD2_k127_1756752_4 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0000000003962 66.0
HFD2_k127_1756752_5 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 0.0002643 43.0
HFD2_k127_1777705_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005633 446.0
HFD2_k127_1777705_1 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 310.0
HFD2_k127_1790224_0 AMP-binding enzyme C-terminal domain K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001169 273.0
HFD2_k127_1790224_1 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000005922 234.0
HFD2_k127_1790224_2 Alpha beta hydrolase - - - 0.00000000000000000000000000000174 128.0
HFD2_k127_1798915_0 Predicted membrane protein (DUF2157) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001598 244.0
HFD2_k127_1798915_1 CBS domain - - - 0.000000000000000000000000000000000000000001617 160.0
HFD2_k127_1798915_2 - - - - 0.00000002045 55.0
HFD2_k127_1818490_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 415.0
HFD2_k127_1818490_1 DoxX-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 388.0
HFD2_k127_1818490_10 Protein of unknown function (DUF423) - - - 0.00004044 54.0
HFD2_k127_1818490_2 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006149 349.0
HFD2_k127_1818490_3 COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007644 348.0
HFD2_k127_1818490_4 aspartic-type endopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002002 283.0
HFD2_k127_1818490_5 mechanosensitive ion channel K22044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004271 270.0
HFD2_k127_1818490_6 integral membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009855 243.0
HFD2_k127_1818490_7 Thioesterase - - - 0.00000000000000000000000000000000000000000000000000000000000461 215.0
HFD2_k127_1818490_8 Bacterial protein of unknown function (DUF937) - - - 0.00000000000000000000000000006049 122.0
HFD2_k127_1818490_9 - - - - 0.0000000000005915 75.0
HFD2_k127_1838845_0 - - - - 0.000000000000000000000000000000000000000000003478 182.0
HFD2_k127_1838845_1 - - - - 0.00000000000000000000000000000000000000000002535 177.0
HFD2_k127_1838845_2 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000000000000000000000000000002114 140.0
HFD2_k127_1838845_3 - - - - 0.0000008465 58.0
HFD2_k127_1842738_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 4.408e-195 616.0
HFD2_k127_1842738_1 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002277 259.0
HFD2_k127_1842738_11 TIR domain - - - 0.00001242 49.0
HFD2_k127_1842738_2 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000587 224.0
HFD2_k127_1842738_3 hemolysin III K11068 - - 0.00000000000000000000000000000000000000000000000000000000000003025 222.0
HFD2_k127_1842738_4 lysine exporter protein (LysE YggA) - - - 0.000000000000000000000000000000000000000000000000000000000006682 213.0
HFD2_k127_1842738_5 Prolyl 4-hydroxylase alpha subunit homologues. K00472 - 1.14.11.2 0.000000000000000000000000000000000000000000000000000001246 206.0
HFD2_k127_1842738_6 - - - - 0.00000000000000000000000000000000000000000003637 166.0
HFD2_k127_1842738_7 Usg-like family - - - 0.000000000000000000000000002585 114.0
HFD2_k127_1842738_8 Prolyl 4-hydroxylase alpha subunit homologues. K00472 - 1.14.11.2 0.0000000000000000000004504 96.0
HFD2_k127_1842738_9 - - - - 0.000000000001688 75.0
HFD2_k127_1865791_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00322 - 1.6.1.1 1.286e-215 678.0
HFD2_k127_1865791_1 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009545 469.0
HFD2_k127_1865791_10 Domain of unknown function (DUF4105) - - - 0.00000000000000000000000000000000000000000000000000000000000001712 225.0
HFD2_k127_1865791_11 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000005262 225.0
HFD2_k127_1865791_12 PFAM Glutathione S-transferase domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000003562 164.0
HFD2_k127_1865791_13 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07659 - - 0.00000000000000000000000000000000000000004475 154.0
HFD2_k127_1865791_14 Putative bacterial sensory transduction regulator - - - 0.00000000000000000000000000000000006014 140.0
HFD2_k127_1865791_15 Heat shock 70 kDa protein - - - 0.000000000000000002371 98.0
HFD2_k127_1865791_16 Membrane fusogenic activity K09806 - - 0.000000000000000003556 88.0
HFD2_k127_1865791_17 GCN5-related N-acetyl-transferase K06975 - - 0.0005123 43.0
HFD2_k127_1865791_2 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003591 440.0
HFD2_k127_1865791_3 Phosphoribosyl pyrophosphate synthetase K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 441.0
HFD2_k127_1865791_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07638 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004485 394.0
HFD2_k127_1865791_5 C-terminal domain of 1-Cys peroxiredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007967 373.0
HFD2_k127_1865791_6 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000969 353.0
HFD2_k127_1865791_7 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 316.0
HFD2_k127_1865791_8 Putative S-adenosyl-L-methionine-dependent methyltransferase K00574,K18164 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 319.0
HFD2_k127_1865791_9 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000472 273.0
HFD2_k127_1867078_0 Thioredoxin K05838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004085 335.0
HFD2_k127_1867078_1 Acyl-CoA thioesterase K10805 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005983 333.0
HFD2_k127_1867078_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 325.0
HFD2_k127_1867078_3 peptidase M19 K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 332.0
HFD2_k127_1867078_4 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000001041 241.0
HFD2_k127_1867078_5 YbaK prolyl-tRNA synthetase K19055 - - 0.000000000000000000000000000000000000000000000000000000001034 206.0
HFD2_k127_1867078_6 to the N-terminal domain of Lon protease K01338,K07157 - 3.4.21.53 0.00000000000000000000000000000000000000000004428 165.0
HFD2_k127_1867078_7 nuclease - - - 0.0000000002169 68.0
HFD2_k127_189226_0 Domain of unknown function DUF21 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004464 421.0
HFD2_k127_189226_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 380.0
HFD2_k127_189226_2 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.000000000000000000000000000000000000000000000000000000000414 207.0
HFD2_k127_1968656_0 Amidohydrolase family K01465 - 3.5.2.3 2.442e-205 647.0
HFD2_k127_1968656_1 Glycosyltransferase family 9 (heptosyltransferase) K02843,K02849 - - 0.0000000000000000000007678 101.0
HFD2_k127_2002719_0 localization factor protein PodJ K07126,K13582 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006541 369.0
HFD2_k127_2002719_1 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002951 306.0
HFD2_k127_2002719_2 Putative transmembrane protein (Alph_Pro_TM) - - - 0.0000000000005036 74.0
HFD2_k127_2021429_0 COG3119 Arylsulfatase A and related enzymes K01130,K01138 - 3.1.6.1 5.966e-202 645.0
HFD2_k127_2021429_1 acyl-CoA dehydrogenase - - - 7.265e-195 614.0
HFD2_k127_2021429_10 Protein of unknown function (DUF1289) K06938 - - 0.000000000000000009972 85.0
HFD2_k127_2021429_11 calcium- and calmodulin-responsive adenylate cyclase activity K01406 - 3.4.24.40 0.000000309 55.0
HFD2_k127_2021429_12 - - - - 0.00008218 50.0
HFD2_k127_2021429_13 - - - - 0.0001146 49.0
HFD2_k127_2021429_2 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 455.0
HFD2_k127_2021429_3 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003919 418.0
HFD2_k127_2021429_4 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001878 279.0
HFD2_k127_2021429_5 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate - - - 0.0000000000000000000000000000000000000000000000000000003283 199.0
HFD2_k127_2021429_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000003639 175.0
HFD2_k127_2021429_7 Protein of unknown function (DUF1345) - - - 0.00000000000000000000000000000000001942 144.0
HFD2_k127_2021429_8 Belongs to the 'phage' integrase family - - - 0.000000000000000004003 87.0
HFD2_k127_2021429_9 Cytochrome c - - - 0.000000000000000006309 88.0
HFD2_k127_2053599_0 Fibronectin type 3 domain - - - 1.387e-203 642.0
HFD2_k127_2053599_1 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 0.0000000000000000000000000000000000000000000000001156 183.0
HFD2_k127_2065455_0 Oxidoreductase - - - 2.386e-312 960.0
HFD2_k127_2065455_1 Glycine cleavage T-protein C-terminal barrel domain - - - 9.225e-211 661.0
HFD2_k127_2065455_2 ABC transporter K06147 GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006996,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009507,GO:0009526,GO:0009536,GO:0009555,GO:0009657,GO:0009658,GO:0009889,GO:0009941,GO:0009987,GO:0010035,GO:0010038,GO:0010288,GO:0010380,GO:0016020,GO:0016043,GO:0018130,GO:0019222,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0019866,GO:0022622,GO:0030003,GO:0031090,GO:0031323,GO:0031326,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0042221,GO:0042592,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0046686,GO:0046916,GO:0048229,GO:0048364,GO:0048731,GO:0048856,GO:0048878,GO:0050789,GO:0050790,GO:0050794,GO:0050801,GO:0050896,GO:0051171,GO:0051186,GO:0051188,GO:0051189,GO:0051193,GO:0051276,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0065009,GO:0071704,GO:0071840,GO:0090056,GO:0090407,GO:0098771,GO:0099402,GO:1901360,GO:1901362,GO:1901401,GO:1901463,GO:1901564,GO:1901566,GO:1901576 - 2.139e-197 634.0
HFD2_k127_2065455_3 Thi4 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006468 390.0
HFD2_k127_2065455_4 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000007784 224.0
HFD2_k127_2065455_5 Prolyl 4-hydroxylase alpha subunit homologues. K00472 - 1.14.11.2 0.0000000000000000000000000000000000000000000000000002751 197.0
HFD2_k127_2065455_6 SelR domain - - - 0.0000000000000000000000000000000000000000000000000005717 188.0
HFD2_k127_2065455_7 Glutathione S-transferase - - - 0.0000000000000000000000000000000002577 151.0
HFD2_k127_2065455_8 - - - - 0.000000000001433 72.0
HFD2_k127_2065455_9 Thi4 family - - - 0.0000001604 54.0
HFD2_k127_2067789_0 NfeD-like C-terminal, partner-binding K07340 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000001207 69.0
HFD2_k127_2076835_0 Major Facilitator Superfamily K08224 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 433.0
HFD2_k127_2076835_1 KR domain K00019 - 1.1.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 364.0
HFD2_k127_2076835_2 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000004889 199.0
HFD2_k127_2076835_3 Cupin domain - - - 0.000000000000000000000000000000000000000000003997 168.0
HFD2_k127_2095978_0 peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 289.0
HFD2_k127_2095978_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000001808 229.0
HFD2_k127_2106822_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 1.085e-219 704.0
HFD2_k127_2106822_1 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003312 454.0
HFD2_k127_2106822_2 flavoprotein involved in K transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008071 258.0
HFD2_k127_2106822_3 - - - - 0.0000000000000000000000000000000000000000000005969 166.0
HFD2_k127_2106822_4 Universal stress protein UspA - - - 0.0000000000000000000000000000000000000000001061 170.0
HFD2_k127_2106822_5 FixH - - - 0.00000000000000000000001067 107.0
HFD2_k127_2106822_6 cytochrome oxidase maturation protein - - - 0.0000000000003074 74.0
HFD2_k127_2106822_7 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000003783 59.0
HFD2_k127_2138930_0 COG0308 Aminopeptidase N K01256 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0016020,GO:0016787,GO:0019538,GO:0033218,GO:0042277,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.11.2 2.388e-283 894.0
HFD2_k127_2138930_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 3.554e-235 759.0
HFD2_k127_2138930_10 - - - - 0.000000000007541 71.0
HFD2_k127_2138930_11 Heavy-metal resistance - - - 0.0001224 52.0
HFD2_k127_2138930_2 acyl-CoA dehydrogenase K11731 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 578.0
HFD2_k127_2138930_3 COG1960 Acyl-CoA dehydrogenases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005956 500.0
HFD2_k127_2138930_4 Non-motile and phage-resistance protein K07716 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 466.0
HFD2_k127_2138930_5 - - - - 0.000000000000000000000000000000000000000000000000000000009738 207.0
HFD2_k127_2138930_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000001243 202.0
HFD2_k127_2138930_7 - - - - 0.0000000000000000000000000000003404 130.0
HFD2_k127_2138930_8 Histidine kinase - - - 0.0000000000000000000009112 96.0
HFD2_k127_2138930_9 Destroys radicals which are normally produced within the cells and which are toxic to biological systems - - - 0.000000000004275 70.0
HFD2_k127_2141888_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007157 593.0
HFD2_k127_2141888_1 COG4206 Outer membrane cobalamin receptor protein K16092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 410.0
HFD2_k127_2152125_0 GMC oxidoreductase K00108 - 1.1.99.1 7.054e-240 753.0
HFD2_k127_2152125_1 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008085 475.0
HFD2_k127_2152125_10 protein conserved in bacteria - - - 0.000000000000000000003211 106.0
HFD2_k127_2152125_11 Bacterial protein of unknown function (DUF882) - - - 0.000000000000000000005792 101.0
HFD2_k127_2152125_12 Response regulator receiver - - - 0.0000000000000000002133 94.0
HFD2_k127_2152125_13 PAS domain - - - 0.0000000002139 70.0
HFD2_k127_2152125_2 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000038 231.0
HFD2_k127_2152125_3 Peptidase family M23 K21472 - - 0.00000000000000000000000000000000000000000000000419 184.0
HFD2_k127_2152125_4 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000009438 162.0
HFD2_k127_2152125_5 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.000000000000000000000000000000000000001045 150.0
HFD2_k127_2152125_6 COG0593 ATPase involved in DNA replication initiation - - - 0.000000000000000000000000000000001849 139.0
HFD2_k127_2152125_7 - - - - 0.000000000000000000000000003002 118.0
HFD2_k127_2152125_8 PilZ domain - - - 0.000000000000000000000001243 111.0
HFD2_k127_2152125_9 cheY-homologous receiver domain - - - 0.00000000000000000000031 106.0
HFD2_k127_2154191_0 Methylmalonyl-CoA mutase K01847 - 5.4.99.2 6.22e-241 750.0
HFD2_k127_2154191_1 Glycosyl hydrolases family 25 K07273 - - 0.0000000000000000000000000000000000000000000000000000000004761 210.0
HFD2_k127_2154191_2 COG1884 Methylmalonyl-CoA mutase, N-terminal domain subunit K01847 - 5.4.99.2 0.000000000000000000000000000003875 126.0
HFD2_k127_2187110_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 8.408e-298 924.0
HFD2_k127_2187110_1 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000355 428.0
HFD2_k127_2187110_10 - - - - 0.0000000000004752 73.0
HFD2_k127_2187110_11 - - - - 0.00000001863 59.0
HFD2_k127_2187110_12 ERAD pathway K14026 - - 0.0000004447 63.0
HFD2_k127_2187110_13 Peptidase propeptide and YPEB domain - - - 0.0008163 48.0
HFD2_k127_2187110_2 Ppx GppA K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 403.0
HFD2_k127_2187110_3 Repeat of Unknown Function (DUF347) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 363.0
HFD2_k127_2187110_4 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003922 301.0
HFD2_k127_2187110_5 TIR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000726 237.0
HFD2_k127_2187110_6 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000004337 224.0
HFD2_k127_2187110_7 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000004088 215.0
HFD2_k127_2187110_8 Protein of unknown function (DUF3297) - - - 0.00000000000000000000000000000000006871 135.0
HFD2_k127_2187110_9 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000002808 87.0
HFD2_k127_2191720_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 591.0
HFD2_k127_2191720_1 Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations K01241 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008714,GO:0016787,GO:0016798,GO:0016799,GO:0044424,GO:0044444,GO:0044464 3.2.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 454.0
HFD2_k127_2191720_10 Uncharacterized protein conserved in bacteria (DUF2219) - - - 0.0000004643 60.0
HFD2_k127_2191720_2 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001634 264.0
HFD2_k127_2191720_3 COG2365 Protein tyrosine serine phosphatase K01104 - 3.1.3.48 0.0000000000000000000000000000000000000000000000000000000000005199 219.0
HFD2_k127_2191720_4 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000000000000000000001139 159.0
HFD2_k127_2191720_5 CHAP domain - - - 0.00000000000000000000000000000000000004519 152.0
HFD2_k127_2191720_6 CHAP domain - - - 0.00000000000000000000000000000000000004709 150.0
HFD2_k127_2191720_7 COG2335, Secreted and surface protein containing fasciclin-like repeats - - - 0.0000000000000000000000000006875 123.0
HFD2_k127_2191720_8 molecular chaperone K05801 - - 0.000000000000000000000001056 106.0
HFD2_k127_2191720_9 Uncharacterized protein conserved in bacteria (DUF2219) - - - 0.000000000000007001 84.0
HFD2_k127_2209154_0 peptidase M13 K07386 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006131 529.0
HFD2_k127_2209154_1 M13 family peptidase K01415,K07386 - 3.4.24.71 0.0000000000000000000000000000000000000000000000000000007628 202.0
HFD2_k127_2211875_0 COG1702 Phosphate starvation-inducible protein PhoH K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 336.0
HFD2_k127_2211875_1 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000000000000000000000005407 235.0
HFD2_k127_2211875_2 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000000000007466 91.0
HFD2_k127_2229686_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 3.276e-254 789.0
HFD2_k127_2229686_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004579 505.0
HFD2_k127_2229686_10 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000003741 126.0
HFD2_k127_2229686_11 Peptidase family M23 - - - 0.0000000000000000000000000008242 126.0
HFD2_k127_2229686_12 threonine efflux protein - - - 0.0008703 43.0
HFD2_k127_2229686_2 ATP synthase subunit gamma, mitochondrial - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 346.0
HFD2_k127_2229686_3 Divergent polysaccharide deacetylase K09798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002844 291.0
HFD2_k127_2229686_4 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001546 245.0
HFD2_k127_2229686_5 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.000000000000000000000000000000000000000000000000000000000000001486 222.0
HFD2_k127_2229686_6 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.000000000000000000000000000000000000000000000001179 187.0
HFD2_k127_2229686_7 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000001394 163.0
HFD2_k127_2229686_8 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000000000006991 154.0
HFD2_k127_2229686_9 PFAM OsmC family protein - - - 0.0000000000000000000000000000000001032 137.0
HFD2_k127_224657_0 Polysaccharide biosynthesis protein K13013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002076 263.0
HFD2_k127_224657_1 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.000000000000000000000000000000000000000000000000000000006479 215.0
HFD2_k127_224657_2 membrane fusion protein K02022 - - 0.000000007456 57.0
HFD2_k127_2249737_0 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 421.0
HFD2_k127_2249737_1 Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000227 287.0
HFD2_k127_2249737_2 Haloacid dehalogenase-like hydrolase K07025 - - 0.000000000000000000000000000000000000000000000000003131 188.0
HFD2_k127_2249737_3 NfeD-like C-terminal, partner-binding K07340 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000005258 92.0
HFD2_k127_2283720_0 Trypsin-like serine protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004522 453.0
HFD2_k127_2283720_1 protein involved in formation of curli polymers - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005123 277.0
HFD2_k127_2283720_2 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000001556 207.0
HFD2_k127_2283720_3 peptidyl-prolyl cis-trans isomerase K03773 - 5.2.1.8 0.000000000000000000000000001019 119.0
HFD2_k127_2301421_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.617e-255 798.0
HFD2_k127_2301421_1 cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 601.0
HFD2_k127_2301421_2 2-polyprenylphenol 6-hydroxylase K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004053 505.0
HFD2_k127_2301421_3 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004602 471.0
HFD2_k127_2301421_4 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009634 369.0
HFD2_k127_2301421_5 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 354.0
HFD2_k127_2301421_6 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004706 345.0
HFD2_k127_2301421_7 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 290.0
HFD2_k127_2301421_8 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.0000000000000000000000000000000000000000000000000000000000000000000005637 255.0
HFD2_k127_2301421_9 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000000000000004136 98.0
HFD2_k127_2308208_0 Hydantoinase/oxoprolinase N-terminal region K01469 - 3.5.2.9 0.0 1453.0
HFD2_k127_2308208_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 4.15e-315 973.0
HFD2_k127_2308208_10 Glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.000000000000000000000000000000000000000000000000000000000000000002716 229.0
HFD2_k127_2308208_11 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000007286 234.0
HFD2_k127_2308208_12 Heparinase II/III-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000001592 222.0
HFD2_k127_2308208_13 dienelactone hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000001436 219.0
HFD2_k127_2308208_14 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000001693 190.0
HFD2_k127_2308208_15 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.00000000000000000000000000000000000000000000000004994 188.0
HFD2_k127_2308208_16 - K12541 - - 0.0000000000000000000000000000008555 126.0
HFD2_k127_2308208_17 membrane - - - 0.0000000000000000000003813 114.0
HFD2_k127_2308208_18 - K12541 - - 0.000000000000000115 82.0
HFD2_k127_2308208_2 COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, gamma subunit K00174 - 1.2.7.11,1.2.7.3 2.378e-280 872.0
HFD2_k127_2308208_20 Predicted membrane protein (DUF2339) - - - 0.0001101 56.0
HFD2_k127_2308208_3 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 3.701e-230 728.0
HFD2_k127_2308208_4 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 1.59e-225 700.0
HFD2_k127_2308208_5 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009284 559.0
HFD2_k127_2308208_6 Protein of unknown function (DUF2891) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008381 428.0
HFD2_k127_2308208_7 Protein of unknown function (DUF979) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004303 393.0
HFD2_k127_2308208_8 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 302.0
HFD2_k127_2308208_9 fumarylacetoacetate (FAA) hydrolase K16165 - 3.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 299.0
HFD2_k127_2349922_0 M13 family peptidase K01415,K07386 - 3.4.24.71 1.139e-213 682.0
HFD2_k127_2349922_1 Glycosyl transferase family 21 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006427 461.0
HFD2_k127_2349922_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004222 422.0
HFD2_k127_2349922_3 phosphate regulon transcriptional regulatory protein PhoB K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 377.0
HFD2_k127_2349922_4 signal transduction histidine kinase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 332.0
HFD2_k127_2349922_5 Plays a role in the regulation of phosphate uptake K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000993 287.0
HFD2_k127_2360886_0 helicase K03657 - 3.6.4.12 0.0 1020.0
HFD2_k127_2360886_1 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000004375 133.0
HFD2_k127_2360886_2 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000001592 94.0
HFD2_k127_2360886_3 TIR domain - - - 0.00000000005894 65.0
HFD2_k127_2372382_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006398 519.0
HFD2_k127_2372382_1 Protein of unknown function (FYDLN_acid) - - - 0.000000000000000000000003336 108.0
HFD2_k127_2372382_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000002077 76.0
HFD2_k127_2377731_0 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 7.147e-271 856.0
HFD2_k127_2377731_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004065 370.0
HFD2_k127_2377731_2 Belongs to the FPP GGPP synthase family K02523 GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009684 305.0
HFD2_k127_2377731_3 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006084 298.0
HFD2_k127_2377731_4 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000007439 239.0
HFD2_k127_2377731_5 Transglycosylase - - - 0.0000000000000000000000000000000000000000000000000000000002744 222.0
HFD2_k127_2377731_6 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.0000000000000000000000000000000000000000000000000000003867 203.0
HFD2_k127_2377731_7 glycosyl transferase family K02851,K13007 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000001689 190.0
HFD2_k127_2377731_8 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000003126 157.0
HFD2_k127_238764_0 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - GO:0003674,GO:0003700,GO:0004857,GO:0006355,GO:0008073,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0010967,GO:0019219,GO:0019222,GO:0030234,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033238,GO:0042979,GO:0043086,GO:0044092,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 1.041e-202 643.0
HFD2_k127_238764_1 ABC transporter, ATP-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 573.0
HFD2_k127_238764_10 - - - - 0.0000000000000000000000000000000000000156 150.0
HFD2_k127_238764_11 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000000000001573 135.0
HFD2_k127_238764_13 - - - - 0.00000000000000000004659 98.0
HFD2_k127_238764_14 Protein of unknown function (DUF465) - - - 0.0000000000003939 72.0
HFD2_k127_238764_15 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000000005495 66.0
HFD2_k127_238764_16 Protein of unknown function (DUF465) - - - 0.00000001415 57.0
HFD2_k127_238764_17 - - - - 0.000001017 58.0
HFD2_k127_238764_19 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00008172 47.0
HFD2_k127_238764_2 Sodium/hydrogen exchanger family K03455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004659 383.0
HFD2_k127_238764_20 Protein of unknown function (DUF1192) - - - 0.0005679 45.0
HFD2_k127_238764_3 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 377.0
HFD2_k127_238764_4 beta-1,4-mannooligosaccharide phosphorylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004103 375.0
HFD2_k127_238764_5 protein conserved in bacteria K09987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004214 247.0
HFD2_k127_238764_6 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000001423 248.0
HFD2_k127_238764_7 peptidase U32 - - - 0.00000000000000000000000000000000000000000000000000000002146 203.0
HFD2_k127_238764_8 Regulator of CtrA degradation K13592 - - 0.000000000000000000000000000000000000000000002697 169.0
HFD2_k127_238764_9 GGDEF domain - - - 0.00000000000000000000000000000000000000000001033 170.0
HFD2_k127_2413894_0 Fatty acid desaturase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003721 401.0
HFD2_k127_2413894_1 helix_turn_helix, Arsenical Resistance Operon Repressor - GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010035,GO:0010038,GO:0010288,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032791,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046870,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097063,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000008193 246.0
HFD2_k127_2413894_2 NIPSNAP - - - 0.0000000000000000000000000000000000000000000000001218 179.0
HFD2_k127_2413894_3 enzyme involved in biosynthesis of extracellular polysaccharides - - - 0.0000000000000000000000000000000000000000001909 167.0
HFD2_k127_2431996_0 Amidase K01426 - 3.5.1.4 4.077e-230 720.0
HFD2_k127_2431996_1 Thiolase, C-terminal domain K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 594.0
HFD2_k127_2431996_2 Glycosyl transferase group 2 family protein K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003389 327.0
HFD2_k127_2431996_3 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000002322 237.0
HFD2_k127_2431996_4 Polyhydroxyalkanoate synthesis repressor PhaR - - - 0.0000000000000000000000000000000000000000000000000000000000004219 218.0
HFD2_k127_2431996_5 glycosyl transferase family 39 - - - 0.0000000000000000000000000000000000000000000000000000707 207.0
HFD2_k127_2431996_6 - - - - 0.000000000000000000000000000000000000000004646 158.0
HFD2_k127_2431996_7 Protein of unknown function (DUF4199) - - - 0.00000000000000000000005145 100.0
HFD2_k127_2431996_8 Glycosyltransferase like family 2 K07011 - - 0.0000000000000001524 84.0
HFD2_k127_2431996_9 - - - - 0.0000000002549 66.0
HFD2_k127_2445656_0 Glycosyl transferase family 41 - - - 5.788e-209 669.0
HFD2_k127_2445656_1 COG3023 Negative regulator of beta-lactamase expression K00788,K01447,K03806 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 2.5.1.3,3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000004009 251.0
HFD2_k127_2445656_2 molecular chaperone K05801 - - 0.000000000000000000000000000000000000000000738 160.0
HFD2_k127_2505301_0 PFAM Penicillin binding protein transpeptidase domain K05366 - 2.4.1.129,3.4.16.4 9.072e-233 748.0
HFD2_k127_2505301_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003984 524.0
HFD2_k127_2505301_10 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000007067 163.0
HFD2_k127_2505301_11 COG1651 Protein-disulfide isomerase - - - 0.0000000000000000000000000000000000000001646 159.0
HFD2_k127_2505301_12 COG1664 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000000000000000003131 112.0
HFD2_k127_2505301_13 - - - - 0.000000000000000000003551 100.0
HFD2_k127_2505301_14 - - - - 0.0000000000000000004925 93.0
HFD2_k127_2505301_15 ThiS family - - - 0.000000000000001537 80.0
HFD2_k127_2505301_16 - - - - 0.00000001742 66.0
HFD2_k127_2505301_2 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004001 534.0
HFD2_k127_2505301_3 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003523 422.0
HFD2_k127_2505301_4 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 364.0
HFD2_k127_2505301_5 Peptidase M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 356.0
HFD2_k127_2505301_6 Bacterial transcriptional repressor C-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 286.0
HFD2_k127_2505301_7 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000001371 241.0
HFD2_k127_2505301_8 Redoxin K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000002297 214.0
HFD2_k127_2505301_9 Protein of unknown function - - - 0.000000000000000000000000000000000000000000003835 185.0
HFD2_k127_2511303_0 Aspartyl/Asparaginyl beta-hydroxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 325.0
HFD2_k127_2511303_1 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000293 261.0
HFD2_k127_2511303_2 L,D-transpeptidase catalytic domain K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000003884 237.0
HFD2_k127_2511303_3 Crp-like helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000000000000008788 224.0
HFD2_k127_2511303_4 response to cobalt ion - GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0010045,GO:0010243,GO:0030288,GO:0030313,GO:0031975,GO:0032025,GO:0033554,GO:0042221,GO:0042597,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:1901652,GO:1901698,GO:1901700 - 0.00000000000000000000000000000000000000000000000000002554 199.0
HFD2_k127_2511303_5 Diacylglycerol kinase catalytic - - - 0.0000000000000000000000000000000000000000000003979 179.0
HFD2_k127_2511303_6 Universal stress protein - - - 0.000000000000000000000000000001485 134.0
HFD2_k127_2511303_7 Histidine kinase - - - 0.0000000000000000000000000000477 123.0
HFD2_k127_2511303_8 Belongs to the UPF0337 (CsbD) family - - - 0.000000000000003283 78.0
HFD2_k127_258286_0 Berberine and berberine like - - - 1.693e-216 687.0
HFD2_k127_258286_1 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 448.0
HFD2_k127_2612146_0 Spinster homolog 1 K12890 GO:0000003,GO:0000323,GO:0002165,GO:0003006,GO:0003376,GO:0003674,GO:0005215,GO:0005319,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005765,GO:0005768,GO:0005770,GO:0005773,GO:0005774,GO:0006810,GO:0006869,GO:0006897,GO:0006915,GO:0006928,GO:0006950,GO:0006996,GO:0007033,GO:0007034,GO:0007040,GO:0007041,GO:0007154,GO:0007165,GO:0007186,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007399,GO:0007416,GO:0007417,GO:0007422,GO:0007528,GO:0007610,GO:0007617,GO:0007618,GO:0007619,GO:0008150,GO:0008219,GO:0008333,GO:0008347,GO:0008582,GO:0009267,GO:0009605,GO:0009653,GO:0009791,GO:0009886,GO:0009966,GO:0009968,GO:0009987,GO:0009991,GO:0010001,GO:0010008,GO:0010623,GO:0010646,GO:0010648,GO:0010876,GO:0010941,GO:0012501,GO:0012505,GO:0016020,GO:0016043,GO:0016192,GO:0016477,GO:0019098,GO:0019953,GO:0022008,GO:0022412,GO:0022414,GO:0022607,GO:0023051,GO:0023052,GO:0023057,GO:0030154,GO:0031090,GO:0031410,GO:0031667,GO:0031668,GO:0031669,GO:0031902,GO:0031982,GO:0032501,GO:0032502,GO:0032504,GO:0033036,GO:0033554,GO:0035193,GO:0036465,GO:0040007,GO:0040008,GO:0040011,GO:0042063,GO:0042594,GO:0042981,GO:0043067,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043900,GO:0044085,GO:0044087,GO:0044422,GO:0044424,GO:0044433,GO:0044437,GO:0044440,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045476,GO:0045477,GO:0045595,GO:0045924,GO:0046624,GO:0046907,GO:0048468,GO:0048477,GO:0048488,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0048589,GO:0048609,GO:0048638,GO:0048731,GO:0048856,GO:0048869,GO:0048870,GO:0050789,GO:0050793,GO:0050794,GO:0050803,GO:0050807,GO:0050808,GO:0050896,GO:0051124,GO:0051128,GO:0051179,GO:0051234,GO:0051239,GO:0051641,GO:0051649,GO:0051674,GO:0051704,GO:0051716,GO:0051960,GO:0051963,GO:0060180,GO:0060284,GO:0065007,GO:0065008,GO:0071496,GO:0071702,GO:0071840,GO:0080171,GO:0090092,GO:0090097,GO:0090099,GO:0090101,GO:0090520,GO:0097708,GO:0098588,GO:0098657,GO:0098805,GO:0098852,GO:0099003,GO:0099504,GO:1902742,GO:1904396,GO:1904748,GO:1905879,GO:2000026,GO:2000241 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004129 517.0
HFD2_k127_2612146_1 Protease prsW family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001627 246.0
HFD2_k127_2639371_0 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 510.0
HFD2_k127_2639371_1 Transcriptional regulator K04761 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005769 316.0
HFD2_k127_2639371_2 Cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000007493 222.0
HFD2_k127_2639371_3 - - - - 0.000000000000000005583 89.0
HFD2_k127_2689043_0 DNA polymerase K02337 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.0 1153.0
HFD2_k127_2689043_1 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 574.0
HFD2_k127_2689043_2 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007337 524.0
HFD2_k127_2689043_3 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004085 375.0
HFD2_k127_2689043_4 overlaps another CDS with the same product name - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005279 367.0
HFD2_k127_2689043_5 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000267 277.0
HFD2_k127_2689043_6 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004014 274.0
HFD2_k127_2691629_0 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 531.0
HFD2_k127_2691629_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 294.0
HFD2_k127_2691629_2 Diacylglycerol kinase K00901 - 2.7.1.107 0.0000000000000000000000000000000000000009305 154.0
HFD2_k127_2697055_0 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004441 514.0
HFD2_k127_2697055_1 ABC transporter transmembrane region K06148 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 483.0
HFD2_k127_2697055_2 6-phosphogluconate dehydrogenase K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004414 460.0
HFD2_k127_2697055_3 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 460.0
HFD2_k127_2697055_4 Oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002852 285.0
HFD2_k127_2697055_5 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.000000000000000000000000000000000000005897 147.0
HFD2_k127_2697055_6 membrane fusion protein K02022 - - 0.000000000000000000000000000003053 125.0
HFD2_k127_2707616_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 1.333e-236 742.0
HFD2_k127_2707616_1 Uncharacterised protein conserved in bacteria (DUF2336) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000168 287.0
HFD2_k127_2707616_2 Protein of unknown function (DUF1491) - - - 0.000000000000000000000000000002363 123.0
HFD2_k127_2707616_3 COG0488 ATPase components of ABC transporters with duplicated ATPase domains K15738 - - 0.000000000003464 70.0
HFD2_k127_2707616_4 - - - - 0.000004012 53.0
HFD2_k127_2723079_0 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006565 519.0
HFD2_k127_2723079_1 Belongs to the flagella basal body rod proteins family K02391,K02392 - - 0.0000000000000000000000000000000000000000000000000002914 194.0
HFD2_k127_2723079_2 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.000000000000000000000000000000000000000000006823 172.0
HFD2_k127_2723079_3 PFAM MgtE intracellular - - - 0.0000000000000000002056 100.0
HFD2_k127_2723079_4 - - - - 0.000000000003539 71.0
HFD2_k127_2765228_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 325.0
HFD2_k127_2765228_1 Phosphate starvation protein PhoH K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004246 278.0
HFD2_k127_2775975_0 phosphate regulon transcriptional regulatory protein PhoB K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 323.0
HFD2_k127_2775975_1 GcrA cell cycle regulator K13583 - - 0.000000000000000000000000000000000000000000000000000003617 195.0
HFD2_k127_2775975_2 Transport permease protein K01992 - - 0.000000000001521 71.0
HFD2_k127_2777120_0 Aminopeptidase K01262 - 3.4.11.9 1.855e-241 759.0
HFD2_k127_2777120_1 ribosomal protein L11 K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001166 248.0
HFD2_k127_2777120_2 Evidence 4 Homologs of previously reported genes of K09700 - - 0.0000000000000000000000000000000000002832 143.0
HFD2_k127_2777120_3 SnoaL-like domain K06893 - - 0.000000000000000000000000000000131 126.0
HFD2_k127_2777120_4 - - - - 0.000000000000002624 82.0
HFD2_k127_2777120_5 MORN repeat-containing protein K19755 GO:0000226,GO:0001578,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006996,GO:0007010,GO:0007017,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0030030,GO:0030031,GO:0035082,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0044782,GO:0060271,GO:0070925,GO:0071840,GO:0120031,GO:0120036 - 0.0000001509 61.0
HFD2_k127_2781644_0 choline monooxygenase activity K00499 - 1.14.15.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005355 532.0
HFD2_k127_2781644_1 Sugar (and other) transporter K08151 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 398.0
HFD2_k127_2781644_2 COG3000 Sterol desaturase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001895 266.0
HFD2_k127_2781644_3 Protein of unknown function (DUF2834) - - - 0.00000000000000000000000004456 112.0
HFD2_k127_2781644_4 Protein of unknown function (DUF4019) - - - 0.000000008477 64.0
HFD2_k127_2820521_0 protease with the C-terminal PDZ domain - - - 2.719e-243 769.0
HFD2_k127_2820521_1 Uncharacterized ACR, YdiU/UPF0061 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 562.0
HFD2_k127_2820521_10 ArsC family K00537 - 1.20.4.1 0.000000000000000000002144 95.0
HFD2_k127_2820521_11 PFAM Ryanodine receptor Ryr - - - 0.000000000000000000004004 109.0
HFD2_k127_2820521_12 - - - - 0.000000000000001719 81.0
HFD2_k127_2820521_13 ArsC family K00537 - 1.20.4.1 0.0000003248 52.0
HFD2_k127_2820521_2 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006609 563.0
HFD2_k127_2820521_3 lysine 2,3-aminomutase K01843 - 5.4.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 424.0
HFD2_k127_2820521_4 PFAM tRNA synthetase, class II (D, K and N) K04568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006518 378.0
HFD2_k127_2820521_5 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000008423 255.0
HFD2_k127_2820521_6 Sugar (and other) transporter K08151 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002432 258.0
HFD2_k127_2820521_7 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000009792 254.0
HFD2_k127_2820521_8 Acetyltransferase (GNAT) domain K03824 - - 0.0000000000000000000000000000000000000000007724 164.0
HFD2_k127_2820521_9 Lysozyme inhibitor LprI - - - 0.00000000000000000000003709 111.0
HFD2_k127_2825483_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004178 326.0
HFD2_k127_2825599_0 Belongs to the peptidase S1C family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003624 436.0
HFD2_k127_2827278_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071496 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 474.0
HFD2_k127_2827278_1 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006987 345.0
HFD2_k127_2827278_2 Peptidase family S58 - - - 0.000000000000000000000000000000000000000000000000000000000000003024 222.0
HFD2_k127_2830563_0 GTP-binding protein TypA K06207 - - 2.16e-272 849.0
HFD2_k127_2830563_1 Peptidase dimerisation domain - - - 9.508e-211 666.0
HFD2_k127_2830563_10 cytochrome K08738 - - 0.000000000000000000000008344 106.0
HFD2_k127_2830563_11 protein conserved in bacteria - - - 0.000000000000543 70.0
HFD2_k127_2830563_2 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 486.0
HFD2_k127_2830563_3 L-lysine 6-monooxygenase (NADPH-requiring) K07222 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 417.0
HFD2_k127_2830563_4 ABC transporter, ATP-binding protein K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003369 413.0
HFD2_k127_2830563_5 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006803 320.0
HFD2_k127_2830563_6 - - - - 0.0000000000000000000000000000000000000000000000000003432 192.0
HFD2_k127_2830563_7 Uncharacterized conserved protein (DUF2277) - - - 0.000000000000000000000000000000001182 140.0
HFD2_k127_2830563_8 Tautomerase enzyme K01821 - 5.3.2.6 0.0000000000000000000000005137 107.0
HFD2_k127_2830563_9 Protein conserved in bacteria K09936 - - 0.0000000000000000000000007456 112.0
HFD2_k127_2832481_0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006568 393.0
HFD2_k127_2832481_1 PFAM flavin reductase domain protein FMN-binding - - - 0.00000000000000000000000000000199 126.0
HFD2_k127_2832481_2 PFAM OmpA MotB domain protein K02557 - - 0.0000000000000000000000001145 106.0
HFD2_k127_2832481_3 chemotaxis protein - - - 0.00000002877 61.0
HFD2_k127_2836171_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 1.178e-242 763.0
HFD2_k127_2836171_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002737 252.0
HFD2_k127_2845028_0 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000005704 208.0
HFD2_k127_2845028_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.000000000000000000000000000000001909 130.0
HFD2_k127_2845028_2 Polymer-forming cytoskeletal - - - 0.00000000000000000459 91.0
HFD2_k127_2857084_0 DJ-1/PfpI family K18199 - 4.2.1.103 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001556 276.0
HFD2_k127_2857084_1 Protein of unknown function (DUF1272) K09984 - - 0.00000000000000000000000000000000002064 136.0
HFD2_k127_2857084_2 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000005946 101.0
HFD2_k127_2857084_3 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000000007972 98.0
HFD2_k127_2860509_0 L-2-hydroxyglutarate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 486.0
HFD2_k127_2860509_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000003421 205.0
HFD2_k127_2860509_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000001482 181.0
HFD2_k127_2860509_3 Dienelactone hydrolase K01061 - 3.1.1.45 0.000000000001365 70.0
HFD2_k127_2869807_0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000007939 137.0
HFD2_k127_2869807_1 periplasmic or secreted lipoprotein - - - 0.000000000000000000000000000000002001 138.0
HFD2_k127_2869807_2 Belongs to the UPF0102 family K07460 - - 0.000000000000004661 81.0
HFD2_k127_2904970_0 Protein of unknown function (DUF1343) - - - 3.899e-215 673.0
HFD2_k127_2904970_1 tRNA synthetases class I (W and Y) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007107 555.0
HFD2_k127_2904970_2 - - - - 0.000000000000000000000000000000000000000006103 159.0
HFD2_k127_2913467_0 peptidase M20 - - - 3.458e-212 669.0
HFD2_k127_2913467_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 360.0
HFD2_k127_2913467_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 342.0
HFD2_k127_2960445_0 AMP-binding enzyme C-terminal domain K01897,K18661 - 6.2.1.3 2.149e-202 640.0
HFD2_k127_2960445_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 392.0
HFD2_k127_2960445_2 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 313.0
HFD2_k127_2960445_3 Short-chain dehydrogenase reductase sdr - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005314 254.0
HFD2_k127_2960445_4 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000008416 248.0
HFD2_k127_2960445_5 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000007869 236.0
HFD2_k127_2962308_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 1.537e-262 825.0
HFD2_k127_2962308_1 ATPase family associated with various cellular activities (AAA) K10943 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007506 611.0
HFD2_k127_2962308_2 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007553 478.0
HFD2_k127_2962308_3 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02417 GO:0005575,GO:0005623,GO:0005886,GO:0009288,GO:0009425,GO:0016020,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000002024 145.0
HFD2_k127_2962308_4 Flagellar biosynthesis type III secretory pathway protein K02411 - - 0.00000000000000000005114 97.0
HFD2_k127_2962308_5 The M ring may be actively involved in energy transduction K02409 - - 0.000002467 50.0
HFD2_k127_2981234_0 high-affinity sulfate:proton symporter activity K06203 GO:0000096,GO:0000097,GO:0000103,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0008150,GO:0008152,GO:0008271,GO:0008272,GO:0008324,GO:0008509,GO:0008512,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009675,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015103,GO:0015116,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015296,GO:0015318,GO:0015672,GO:0015698,GO:0016020,GO:0016021,GO:0016053,GO:0019344,GO:0019752,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044425,GO:0044459,GO:0044464,GO:0046394,GO:0051179,GO:0051234,GO:0055085,GO:0071704,GO:0071944,GO:0072348,GO:0098655,GO:0098656,GO:0098660,GO:0098661,GO:0098662,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901682,GO:1902358,GO:1902600 - 0.00000000000000000000000000000000000000000000000000000000000000003006 230.0
HFD2_k127_2981234_1 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000003997 190.0
HFD2_k127_3002321_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666,K02182,K20034 - 6.2.1.44,6.2.1.48 8.175e-227 715.0
HFD2_k127_3002321_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 559.0
HFD2_k127_3002321_10 Protein of unknown function (DUF2385) - - - 0.000000177 58.0
HFD2_k127_3002321_11 Uncharacterized protein conserved in bacteria (DUF2059) K09924 - - 0.0002693 50.0
HFD2_k127_3002321_2 COG0500 SAM-dependent methyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 396.0
HFD2_k127_3002321_3 Belongs to the amidase family K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006101 387.0
HFD2_k127_3002321_4 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 GO:0003674,GO:0003824,GO:0004733,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.4.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006938 298.0
HFD2_k127_3002321_5 Pfam Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003907 299.0
HFD2_k127_3002321_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000003635 222.0
HFD2_k127_3002321_7 Putative zinc- or iron-chelating domain K09160 - - 0.0000000000000000000000000000000000000000000000000000000000006133 215.0
HFD2_k127_3002321_8 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000007544 169.0
HFD2_k127_3002321_9 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000002538 102.0
HFD2_k127_3064018_0 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007058 533.0
HFD2_k127_3064018_1 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 318.0
HFD2_k127_3064018_2 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000000000000000000005005 190.0
HFD2_k127_3064018_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000006447 145.0
HFD2_k127_3064018_4 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000000000103 145.0
HFD2_k127_3064018_5 CAAX protease self-immunity K07052 - - 0.0000000000002262 81.0
HFD2_k127_3093367_0 PFAM band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001107 282.0
HFD2_k127_3093367_1 Peroxiredoxin-5, mitochondrial K11187 GO:0002682,GO:0002683,GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005777,GO:0005829,GO:0006950,GO:0006979,GO:0007275,GO:0007568,GO:0008150,GO:0008152,GO:0008340,GO:0008379,GO:0009056,GO:0009636,GO:0009987,GO:0010259,GO:0010941,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0019725,GO:0031347,GO:0031348,GO:0032501,GO:0032502,GO:0042221,GO:0042579,GO:0042592,GO:0042737,GO:0042743,GO:0042744,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0045088,GO:0045454,GO:0045824,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0048856,GO:0050776,GO:0050777,GO:0050789,GO:0050794,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0051920,GO:0055114,GO:0060548,GO:0065007,GO:0065008,GO:0070887,GO:0072593,GO:0080134,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000001717 224.0
HFD2_k127_3093367_2 Belongs to the UPF0301 (AlgH) family K07735 - - 0.0000000000000000000000000000000000000000000000000000005437 205.0
HFD2_k127_3093367_3 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000001232 50.0
HFD2_k127_310976_0 DNA gyrase C-terminal domain, beta-propeller K03164 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 596.0
HFD2_k127_310976_1 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 361.0
HFD2_k127_310976_2 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000007762 237.0
HFD2_k127_310976_3 Transcriptional regulator, Crp Fnr family - - - 0.000000000000000000000000000000000000000000000000002548 183.0
HFD2_k127_310976_4 positive regulation of macromolecule biosynthetic process K03973 - - 0.000000000000000000000000000000000000000000001543 179.0
HFD2_k127_310976_5 Histidine kinase - - - 0.000000000000000000000000000000000000001142 158.0
HFD2_k127_310976_6 negative regulation of transcription, DNA-templated K10947 - - 0.0000000000000000000000000000000000009892 141.0
HFD2_k127_3112010_0 Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007769 296.0
HFD2_k127_3112010_1 Iron-sulphur cluster biosynthesis K13628,K15724 - - 0.0000000000000000000000000000000000009892 141.0
HFD2_k127_3112010_2 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.00000001934 63.0
HFD2_k127_3112010_3 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.00000007237 64.0
HFD2_k127_3140466_0 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006256 511.0
HFD2_k127_3140466_1 Beta-N-acetylhexosaminidase K01207,K05349 - 3.2.1.21,3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 325.0
HFD2_k127_3140466_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000002125 174.0
HFD2_k127_3140466_3 Sporulation related domain - - - 0.00000000000000000001084 100.0
HFD2_k127_3146499_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006331 380.0
HFD2_k127_3146499_1 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000007187 125.0
HFD2_k127_3146499_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000002949 83.0
HFD2_k127_3180575_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007833 499.0
HFD2_k127_3180575_1 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000001568 75.0
HFD2_k127_3180575_2 Acetyltransferase (GNAT) domain - - - 0.00000000000001781 86.0
HFD2_k127_3180575_3 - - - - 0.000000000003363 71.0
HFD2_k127_3217270_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 0.00000000000000000000000000000000000000000000000007104 180.0
HFD2_k127_3217270_1 acid phosphatase K09474 - 3.1.3.2 0.0000000000000000000000000000000016 144.0
HFD2_k127_3236305_0 Mur ligase family, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 607.0
HFD2_k127_3236305_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 401.0
HFD2_k127_3236305_2 carboxylic ester hydrolase activity K03929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004991 344.0
HFD2_k127_3322488_0 cassette sub-family B member 6 K05661 - - 8.16e-207 662.0
HFD2_k127_3322488_1 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179,K06125 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004299 295.0
HFD2_k127_3322488_2 endonuclease III - - - 0.000000000000000000000000000000000000000009268 159.0
HFD2_k127_3322488_3 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000002759 95.0
HFD2_k127_3343519_0 Sulfate ABC transporter, periplasmic sulfate-binding protein K02048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 445.0
HFD2_k127_3343519_1 TIGRFAM sulfate ABC transporter K02046 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007011 353.0
HFD2_k127_3343519_2 ABC transporter K02047 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 339.0
HFD2_k127_3343519_3 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.0000000000000000000000002284 106.0
HFD2_k127_3365608_0 Required for chromosome condensation and partitioning K03529 - - 1.373e-255 827.0
HFD2_k127_3365608_1 DSBA oxidoreductase - - - 0.000000000000000000000000000000000000000009632 163.0
HFD2_k127_3365608_2 DSBA oxidoreductase - - - 0.00000000000000000000000000000000000000001784 160.0
HFD2_k127_3365608_3 FES K03575 GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000001056 102.0
HFD2_k127_3365608_4 Protein of unknown function (DUF721) - - - 0.0000002447 61.0
HFD2_k127_3379110_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K02337,K14162 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.0 1169.0
HFD2_k127_3379110_1 helicase K03654 GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008270,GO:0009295,GO:0009378,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017116,GO:0017117,GO:0030894,GO:0032392,GO:0032508,GO:0032991,GO:0032993,GO:0033202,GO:0033554,GO:0034641,GO:0042623,GO:0043138,GO:0043140,GO:0043142,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494,GO:1904949 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 526.0
HFD2_k127_3379110_2 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005999 409.0
HFD2_k127_3379110_3 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 329.0
HFD2_k127_3379110_4 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008516 302.0
HFD2_k127_3379110_5 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001393 263.0
HFD2_k127_3379110_6 Belongs to the ompA family K03286 - - 0.0000000000000000000000000002871 132.0
HFD2_k127_3379110_7 rRNA binding - - - 0.0000000000000000000000001871 120.0
HFD2_k127_3379110_8 SOS response K14160 - - 0.000000000000000000005314 100.0
HFD2_k127_3379291_0 L-aspartate oxidase K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000463 590.0
HFD2_k127_3379291_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009241 523.0
HFD2_k127_3379291_10 SURF1-like protein K14998 - - 0.00000000000000000004038 101.0
HFD2_k127_3379291_2 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3 K02276 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009496 404.0
HFD2_k127_3379291_3 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006416 336.0
HFD2_k127_3379291_4 PFAM peptidase M16 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009812 325.0
HFD2_k127_3379291_5 COG2821 Membrane-bound lytic murein transglycosylase K08304 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007382 256.0
HFD2_k127_3379291_6 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.00000000000000000000000000000000000000000000000000000000000000000003279 236.0
HFD2_k127_3379291_7 Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I K02258 - - 0.000000000000000000000000000000000000000000000000006192 188.0
HFD2_k127_3379291_8 Protein of unknown function (DUF983) - - - 0.0000000000000000000000000000005391 126.0
HFD2_k127_3379291_9 Peptidase family M23 - - - 0.00000000000000000000000000006982 126.0
HFD2_k127_338338_0 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000003086 261.0
HFD2_k127_338338_1 Belongs to the peptidase S41A family - - - 0.000000000000008128 81.0
HFD2_k127_3413804_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 457.0
HFD2_k127_3413804_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 442.0
HFD2_k127_3413804_10 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000002551 121.0
HFD2_k127_3413804_11 Molybdopterin converting factor, small subunit K03636 - - 0.000000000005692 70.0
HFD2_k127_3413804_2 NnrS protein K07234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 407.0
HFD2_k127_3413804_3 TIGRFAM molybdenum cofactor synthesis domain K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008472 336.0
HFD2_k127_3413804_4 cyclic nucleotide-binding K13642 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 307.0
HFD2_k127_3413804_5 Major Facilitator Superfamily K02575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005377 276.0
HFD2_k127_3413804_6 May be involved in the biosynthesis of molybdopterin K03638 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0042802,GO:0044424,GO:0044444,GO:0044464 2.7.7.75 0.00000000000000000000000000000000000000000000000000000000000000000000000001082 256.0
HFD2_k127_3413804_7 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000001228 223.0
HFD2_k127_3413804_8 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000000005511 197.0
HFD2_k127_3413804_9 Molybdopterin K03635 - 2.8.1.12 0.00000000000000000000000000007546 127.0
HFD2_k127_3422476_0 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.0000000000000000000000000000000000000000000000000000000000000000001848 239.0
HFD2_k127_3422476_1 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000003311 228.0
HFD2_k127_3422476_2 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.0000000000000000000000000000000000000000000000000000000844 204.0
HFD2_k127_3422476_3 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.00000000000000000000000000000000000729 139.0
HFD2_k127_3422476_4 Belongs to the bacterial ribosomal protein bL33 family K02913 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000421 102.0
HFD2_k127_3422476_5 Putative auto-transporter adhesin, head GIN domain - - - 0.000000000000000000009582 100.0
HFD2_k127_3425014_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 2.031e-254 796.0
HFD2_k127_3425014_1 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 427.0
HFD2_k127_3425014_2 RmlD substrate binding domain K21271,K22320 - 1.1.1.394,1.1.1.412 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004678 295.0
HFD2_k127_3425014_3 Asp/Glu/Hydantoin racemase K01779 - 5.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000006965 263.0
HFD2_k127_3425014_4 WD40 repeats - - - 0.0001847 45.0
HFD2_k127_3435407_0 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005271 369.0
HFD2_k127_3435407_1 NADH ubiquinone oxidoreductase 17.2 kD subunit K00356 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000003289 206.0
HFD2_k127_3435407_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000003789 137.0
HFD2_k127_3435407_3 PFAM Mammalian cell entry related domain protein K02067 - - 0.000000000000000000000000000000008455 133.0
HFD2_k127_3435407_4 protein conserved in bacteria - - - 0.00000000000000000000001108 109.0
HFD2_k127_3435407_5 Protein of unknown function (DUF1761) - - - 0.000000009629 63.0
HFD2_k127_3444600_0 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000632 327.0
HFD2_k127_3444600_1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000000000000000000000000000000000009792 164.0
HFD2_k127_3444600_2 COG0768 Cell division protein FtsI penicillin-binding protein 2 K03587 - 3.4.16.4 0.00000000000000000000000000001081 124.0
HFD2_k127_3444600_4 - - - - 0.00000228 51.0
HFD2_k127_3444600_5 secreted (periplasmic) protein - - - 0.000008332 52.0
HFD2_k127_3513576_0 COG3540 Phosphodiesterase alkaline phosphatase D K01077,K01113 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 521.0
HFD2_k127_3513576_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000001089 246.0
HFD2_k127_3513576_2 sarcosine oxidase - - - 0.0000000000000000000000000000000000000000002639 173.0
HFD2_k127_3513576_3 Protein of unknown function (DUF817) - - - 0.00000000000000008561 83.0
HFD2_k127_3570784_0 TIGRFAM pyridoxal phosphate-dependent enzymes, D-cysteine desulfhydrase family K17950 - 4.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 467.0
HFD2_k127_3570784_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003065 428.0
HFD2_k127_3570784_2 Belongs to the aspartate glutamate racemases family K01779 - 5.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000001143 243.0
HFD2_k127_3570784_3 Two component transcriptional regulator, winged helix family K07659 - - 0.00000000000000000000000000000000008341 136.0
HFD2_k127_3571110_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K12256 - 2.6.1.113 8.825e-225 708.0
HFD2_k127_3571110_1 glutamine synthetase K01915 - 6.3.1.2 3.036e-197 625.0
HFD2_k127_3571110_10 Aminotransferase class-III - - - 0.0000000000000000000000000000000000000000000000000000000000002743 216.0
HFD2_k127_3571110_11 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000000000001084 165.0
HFD2_k127_3571110_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072,K11076 - 3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 588.0
HFD2_k127_3571110_3 Penicillin amidase K01434,K07116 - 3.5.1.11,3.5.1.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005971 550.0
HFD2_k127_3571110_4 Oxidoreductase K09471 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 521.0
HFD2_k127_3571110_5 Required for the activity of the bacterial periplasmic transport system of putrescine K11069,K11073 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 494.0
HFD2_k127_3571110_6 PFAM binding-protein-dependent transport systems inner membrane component K11071,K11075 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009947 472.0
HFD2_k127_3571110_7 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 462.0
HFD2_k127_3571110_8 Spermidine putrescine ABC transporter, permease K11070,K11074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 439.0
HFD2_k127_3571110_9 Peptidase C26 K07010 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006806 333.0
HFD2_k127_359429_0 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 320.0
HFD2_k127_359429_1 - - - - 0.0000000000005173 80.0
HFD2_k127_3628639_0 Castor and Pollux, part of voltage-gated ion channel - - - 3.593e-212 676.0
HFD2_k127_3628639_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009926 527.0
HFD2_k127_3628639_10 hemolysin III K11068 - - 0.000000000000000000000000000000000000000000000000000000000001054 216.0
HFD2_k127_3628639_11 Von Willebrand factor type A K07114 - - 0.00000000000000000000000000000000000000000000000000399 185.0
HFD2_k127_3628639_12 DNA mismatch endonuclease Vsr K07458 - - 0.00000000000000000000000000000000000000000005063 169.0
HFD2_k127_3628639_13 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000003818 175.0
HFD2_k127_3628639_14 Belongs to the Fur family K09823 - - 0.0000000000000000000000000000000007151 136.0
HFD2_k127_3628639_15 GIY-YIG catalytic domain K07461 - - 0.00000000000000000000000000001129 122.0
HFD2_k127_3628639_16 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000002633 106.0
HFD2_k127_3628639_17 COG0322 Nuclease subunit of the excinuclease complex - - - 0.00000002049 61.0
HFD2_k127_3628639_18 Type III secretion system lipoprotein chaperone (YscW) K09914 - - 0.0000004233 61.0
HFD2_k127_3628639_19 - - - - 0.000007772 53.0
HFD2_k127_3628639_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family K00558 - 2.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 409.0
HFD2_k127_3628639_3 delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase K12663 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006423 404.0
HFD2_k127_3628639_4 Sulfite exporter TauE/SafE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 307.0
HFD2_k127_3628639_5 thiolester hydrolase activity K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001624 283.0
HFD2_k127_3628639_6 Thioesterase K07107 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005392 258.0
HFD2_k127_3628639_7 delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase K12663 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000006603 238.0
HFD2_k127_3628639_8 PFAM alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001386 242.0
HFD2_k127_3628639_9 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000000001379 230.0
HFD2_k127_3655276_0 ATP dependent DNA ligase C terminal region K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005023 471.0
HFD2_k127_3655276_1 Enoyl-(Acyl carrier protein) reductase K13775 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 465.0
HFD2_k127_3655276_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000901 208.0
HFD2_k127_3655276_3 - - - - 0.000000000000001137 81.0
HFD2_k127_3663103_1 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000006774 166.0
HFD2_k127_3682214_0 Belongs to the peptidase M16 family K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008387 422.0
HFD2_k127_3682214_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007119 388.0
HFD2_k127_3682214_2 Peptidase M16 inactive domain K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 294.0
HFD2_k127_3682214_3 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000004194 169.0
HFD2_k127_3682214_4 Protein of unknown function (DUF3035) - - - 0.00000000000000000000000000000000002975 141.0
HFD2_k127_3682214_5 - - - - 0.0000000000003211 81.0
HFD2_k127_3682214_6 - - - - 0.0000000000008518 79.0
HFD2_k127_3758340_0 sigma-54 factor interaction domain-containing protein K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007082 613.0
HFD2_k127_3758340_1 Signal transduction histidine kinase K13598 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 575.0
HFD2_k127_3758340_2 nitrogen regulation protein NR(I) K07712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 475.0
HFD2_k127_3758340_3 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 329.0
HFD2_k127_3758340_4 Catalyzes the transamination of D-amino acids and their alpha-keto acids K00824 - 2.6.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001009 274.0
HFD2_k127_3758340_5 Signal transduction histidine kinase, nitrogen specific K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000002222 245.0
HFD2_k127_3795402_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 5.299e-235 743.0
HFD2_k127_3795402_1 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 586.0
HFD2_k127_3795402_2 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003869 447.0
HFD2_k127_3795402_3 PFAM acyl-CoA dehydrogenase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 427.0
HFD2_k127_3795402_4 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 373.0
HFD2_k127_3795402_5 Protein of unknown function (DUF1326) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003848 312.0
HFD2_k127_3795402_6 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002436 270.0
HFD2_k127_3795402_7 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000001553 169.0
HFD2_k127_3795402_8 Protein of unknown function (DUF4242) - - - 0.000000000000000000000000000000000001069 144.0
HFD2_k127_3795402_9 Peptidase M16 K07263,K07623 - - 0.0000000000001854 73.0
HFD2_k127_381300_0 beta-1,4-mannooligosaccharide phosphorylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 358.0
HFD2_k127_381300_1 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002518 289.0
HFD2_k127_381300_2 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000000000000001193 222.0
HFD2_k127_381300_3 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000004137 215.0
HFD2_k127_381300_4 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000007288 116.0
HFD2_k127_381300_5 Nickel/cobalt transporter regulator - - - 0.00000000000000000000000003684 113.0
HFD2_k127_381300_6 Protein of unknown function (DUF2842) - - - 0.0000000000006607 71.0
HFD2_k127_3817998_0 Aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 477.0
HFD2_k127_3817998_1 Aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000000000001374 175.0
HFD2_k127_3817998_2 transcriptional regulator - - - 0.0000000000000000000001744 99.0
HFD2_k127_3817998_3 MAPEG family - - - 0.00000000000000000004786 96.0
HFD2_k127_3817998_4 Histidine kinase-like ATPases - - - 0.0000000000252 67.0
HFD2_k127_3817998_5 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K10126 - - 0.0000386 51.0
HFD2_k127_3817998_6 - - - - 0.0001036 50.0
HFD2_k127_3830117_0 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 424.0
HFD2_k127_3830117_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000002622 209.0
HFD2_k127_3830117_2 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000000812 162.0
HFD2_k127_3830117_3 Peptidase M10 serralysin C terminal K01406 - 3.4.24.40 0.0000000000002175 77.0
HFD2_k127_3837390_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1111.0
HFD2_k127_3837390_1 Diguanylate cyclase K13591 - - 0.0000000000000000000000000000000000000002712 165.0
HFD2_k127_3837390_2 CoA-transferase family III K01796 - 5.1.99.4 0.000000000000000008475 83.0
HFD2_k127_3853867_0 MaoC like domain K02618 - 1.2.1.91,3.3.2.12 2.211e-297 924.0
HFD2_k127_3853867_1 enoyl-CoA hydratase K15866 - 5.3.3.18 0.000000000000000000000000008084 111.0
HFD2_k127_3862106_0 Dehydrogenase K00382 - 1.8.1.4 4.495e-209 659.0
HFD2_k127_3862106_1 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 432.0
HFD2_k127_3862106_2 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 335.0
HFD2_k127_3862106_3 Rhodanese-like domain-containing protein - - - 0.00000000000000000000000000000000000000000000000001257 186.0
HFD2_k127_3862106_4 - K01992 - - 0.00000000000000000000000000004262 125.0
HFD2_k127_3869999_0 Acyl-CoA dehydrogenase N terminal K00249 - 1.3.8.7 2.876e-272 848.0
HFD2_k127_3869999_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 531.0
HFD2_k127_3869999_2 FMN-dependent dehydrogenase K00101,K00467 - 1.1.2.3,1.13.12.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 412.0
HFD2_k127_3869999_3 OsmC-like protein - - - 0.00000000000000000000000000000000000000000000000000007684 194.0
HFD2_k127_3869999_4 Regulator - - - 0.0000000000000000000000000000000000004155 145.0
HFD2_k127_3869999_5 localization factor protein PodJ K07126,K13582 - - 0.00000000000000002935 88.0
HFD2_k127_3890908_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000868 552.0
HFD2_k127_3890908_1 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 466.0
HFD2_k127_3890908_2 COG1884 Methylmalonyl-CoA mutase, N-terminal domain subunit K01847 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009123 331.0
HFD2_k127_3890908_3 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000003997 103.0
HFD2_k127_3905559_0 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 469.0
HFD2_k127_3905559_1 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 327.0
HFD2_k127_3905559_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008792 321.0
HFD2_k127_3905559_3 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006373 317.0
HFD2_k127_3905559_4 DNA/RNA non-specific endonuclease K01173 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004187 272.0
HFD2_k127_3905559_5 chemotaxis protein - - - 0.0000000000000000000000000000000000000000000001339 173.0
HFD2_k127_3905559_6 rhamnose metabolic process - - - 0.000000000000000000000000000000000000002798 148.0
HFD2_k127_3905559_7 Heat shock protein K03668 - - 0.0000000004355 67.0
HFD2_k127_3905559_8 - - - - 0.000000006053 64.0
HFD2_k127_3930994_0 COG0488 ATPase components of ABC transporters with duplicated ATPase domains K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008367 514.0
HFD2_k127_3930994_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004605 369.0
HFD2_k127_3930994_2 Protein of unknown function (DUF1295) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 312.0
HFD2_k127_3930994_3 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000001568 157.0
HFD2_k127_3930994_4 - - - - 0.00000000000000000000005035 115.0
HFD2_k127_3953609_0 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008343 384.0
HFD2_k127_3953609_1 Copper binding proteins, plastocyanin/azurin family - - - 0.00000000000000000000005277 104.0
HFD2_k127_3953609_2 Domain of unknown function (DUF4337) - - - 0.00002116 50.0
HFD2_k127_3969294_0 TonB dependent receptor - - - 1.488e-293 921.0
HFD2_k127_3969294_1 His Kinase A (phosphoacceptor) domain K15011 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004831 394.0
HFD2_k127_3969294_2 Chemotaxis protein cheY K15012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003261 279.0
HFD2_k127_3969294_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000006196 229.0
HFD2_k127_3969294_4 Phosphodiester glycosidase - - - 0.000000000000000000000000000000000000000000000006771 176.0
HFD2_k127_3969294_5 FecR protein - - - 0.00000000000000000000000000000000001405 149.0
HFD2_k127_39733_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 4.333e-222 696.0
HFD2_k127_39733_1 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000002676 225.0
HFD2_k127_39733_2 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000004481 78.0
HFD2_k127_3996290_0 synthetase K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 608.0
HFD2_k127_3996290_1 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006767 287.0
HFD2_k127_3996290_2 Iron compound ABC transporter, ATP-binding protein K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000008302 213.0
HFD2_k127_3996290_3 iron ABC transporter periplasmic iron-binding protein K02016 - - 0.000000000000000000000000000000000000000000000000002296 193.0
HFD2_k127_4046772_0 acyl-CoA dehydrogenase K14448 - 1.3.8.12 7.433e-242 758.0
HFD2_k127_4046772_1 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 454.0
HFD2_k127_4046772_2 Cupin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 340.0
HFD2_k127_4046772_3 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 289.0
HFD2_k127_4046772_4 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000007766 237.0
HFD2_k127_4046772_5 OsmC-like protein - - - 0.000000000000000000000000000000000000000000000000009251 188.0
HFD2_k127_4046772_6 DoxX K15977 - - 0.00000000000000000000000000000000000000000001813 166.0
HFD2_k127_4046772_7 Immunoglobulin-like domain of bacterial spore germination - - - 0.000000000000004912 80.0
HFD2_k127_4046772_8 META domain - - - 0.0000000008313 66.0
HFD2_k127_4060459_0 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.000000000000000000000000000000000000000295 151.0
HFD2_k127_4060459_1 - - - - 0.000000000000000000000000000006067 136.0
HFD2_k127_4060459_2 - - - - 0.000000002263 64.0
HFD2_k127_4063140_0 cobalamin synthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008852 466.0
HFD2_k127_4063140_1 WD40 repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 317.0
HFD2_k127_4063140_2 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000001196 277.0
HFD2_k127_4063140_3 Patatin-like phospholipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009815 269.0
HFD2_k127_4063140_4 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000002049 240.0
HFD2_k127_4063140_5 AsmA family K07289 - - 0.0000000000000000000000000000000000000000000000000000000000004244 234.0
HFD2_k127_4063140_6 Mur ligase family, glutamate ligase domain - - - 0.00000000003132 74.0
HFD2_k127_4092916_0 Belongs to the pseudouridine synthase RluA family K06179 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000996 275.0
HFD2_k127_4092916_1 Uncharacterized ACR, COG1993 K09137 - - 0.000000000000000000000000000000000000000000000000292 177.0
HFD2_k127_4092916_2 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.00000000000000000000000000000000000007592 148.0
HFD2_k127_4092916_3 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.000000000000000000000000000000004329 134.0
HFD2_k127_4092916_4 pseudouridine synthase K06177,K06179 - 5.4.99.24,5.4.99.28,5.4.99.29 0.00000000000000000000000000000002469 128.0
HFD2_k127_4092916_5 - - - - 0.000000000000000000000000000006723 125.0
HFD2_k127_4109551_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 1.537e-197 620.0
HFD2_k127_4109551_1 Belongs to the GPI family K01810 - 5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 471.0
HFD2_k127_4109551_2 UDP-glucose 4-epimerase K01784,K12448 - 5.1.3.2,5.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 414.0
HFD2_k127_4109551_3 3-methyladenine DNA glycosylase - - - 0.00000000000000000000000000000000000000000000000000000000000003875 233.0
HFD2_k127_4109551_4 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000000000008198 114.0
HFD2_k127_4127158_0 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003996 296.0
HFD2_k127_4127158_1 - K01992 - - 0.000000000000000139 83.0
HFD2_k127_4127158_2 Acetyltransferase (GNAT) domain - - - 0.0000001251 60.0
HFD2_k127_413049_0 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006625 526.0
HFD2_k127_413049_1 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 415.0
HFD2_k127_413049_2 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005733 329.0
HFD2_k127_413049_3 Heparinase II/III-like protein - - - 0.000000000000000000000000000005922 129.0
HFD2_k127_415210_0 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 520.0
HFD2_k127_415210_1 dipeptide transport K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000008122 233.0
HFD2_k127_415210_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000001911 182.0
HFD2_k127_415210_3 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244,K19743 - 1.4.1.1,1.5.1.1,4.3.1.12 0.0000000000000000000000000001959 126.0
HFD2_k127_4161873_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009924 337.0
HFD2_k127_4161873_1 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 304.0
HFD2_k127_4161873_2 Chromosome partitioning protein ParA K03496 - - 0.000000000000000000000000000000000000000000003374 166.0
HFD2_k127_4161873_3 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000953 158.0
HFD2_k127_4161873_4 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000000000001332 96.0
HFD2_k127_4161873_5 - - - - 0.000000000001824 73.0
HFD2_k127_4206225_0 Cytochrome c-type biogenesis protein K02198 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 618.0
HFD2_k127_4206225_1 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 375.0
HFD2_k127_4206225_10 subunit of a heme lyase K02200 - - 0.0000000000000000000000000000003237 128.0
HFD2_k127_4206225_11 Cytochrome c-type biogenesis protein K02200 - - 0.0000000003389 69.0
HFD2_k127_4206225_2 COG0642 Signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003858 338.0
HFD2_k127_4206225_3 COG2214 DnaJ-class molecular chaperone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 325.0
HFD2_k127_4206225_4 Putative phage tail protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 334.0
HFD2_k127_4206225_5 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 308.0
HFD2_k127_4206225_6 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009889,GO:0009893,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010556,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0023052,GO:0031323,GO:0031326,GO:0035556,GO:0042221,GO:0042802,GO:0046688,GO:0048518,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001487 272.0
HFD2_k127_4206225_7 Signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002262 278.0
HFD2_k127_4206225_8 phage portal protein, HK97 - - - 0.0000000000000000000000000000000000000000000000152 177.0
HFD2_k127_4206225_9 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 GO:0003674,GO:0003824,GO:0008150,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840 - 0.000000000000000000000000000000000000000007007 158.0
HFD2_k127_4216480_0 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000004776 199.0
HFD2_k127_4216480_1 HWE histidine kinase - - - 0.0000000000000000000000000000000000000001089 170.0
HFD2_k127_4216480_2 Protein of unknown function (DUF1328) - - - 0.0000000000000000003118 89.0
HFD2_k127_4216480_3 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) - - - 0.00000000003087 70.0
HFD2_k127_4216480_4 Protein of unknown function (DUF1328) - - - 0.0000000003495 62.0
HFD2_k127_4216480_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000009963 51.0
HFD2_k127_4216480_6 ribosome binding - - - 0.00003261 50.0
HFD2_k127_4218064_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 602.0
HFD2_k127_4218064_1 COG0626 Cystathionine beta-lyases cystathionine gamma-synthases K01739 - 2.5.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 376.0
HFD2_k127_4218064_2 3'-5' exonuclease K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 302.0
HFD2_k127_4218064_3 F COG1001 Adenine deaminase - - - 0.00000000000000000000000000000000000000000000000000406 201.0
HFD2_k127_4218064_4 mannose-6-phosphate isomerase - - - 0.0000000000000000000000000000000000000000000000005845 177.0
HFD2_k127_4218064_5 aldo keto reductase - - - 0.000000000000000000000000000000005174 129.0
HFD2_k127_4218064_6 GIY-YIG catalytic domain - - - 0.00000000000000000000000006704 109.0
HFD2_k127_4218064_7 FCD domain - - - 0.0000000000000000000000009107 111.0
HFD2_k127_4218064_8 - - - - 0.00000003136 59.0
HFD2_k127_4219479_0 pyridine nucleotide-disulfide oxidoreductase K00529 - 1.18.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003671 439.0
HFD2_k127_4219479_1 COG3893 Inactivated superfamily I helicase K16899 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009162 372.0
HFD2_k127_4219479_2 phosphotransferase related to Ser Thr protein kinases K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 353.0
HFD2_k127_4219479_3 Nucleotidyl transferase K00992 - 2.7.7.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001135 282.0
HFD2_k127_4219479_4 ferredoxin - - - 0.0000000000000000000000000000000000000000000000000362 179.0
HFD2_k127_4219479_5 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000000000001936 154.0
HFD2_k127_4219479_6 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000000000000000001549 146.0
HFD2_k127_4231061_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 5.061e-220 690.0
HFD2_k127_4231061_1 Alanine dehydrogenase/PNT, C-terminal domain K00324 GO:0000166,GO:0003674,GO:0003824,GO:0003957,GO:0005215,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006740,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0008746,GO:0008750,GO:0009117,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0016491,GO:0016651,GO:0016652,GO:0019362,GO:0019637,GO:0022857,GO:0022890,GO:0034220,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046496,GO:0046983,GO:0048037,GO:0050662,GO:0051179,GO:0051186,GO:0051234,GO:0051287,GO:0055085,GO:0055086,GO:0055114,GO:0070403,GO:0070404,GO:0071704,GO:0072524,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1902600 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006245 457.0
HFD2_k127_4231061_2 Glycosyl transferase, family 2 K16555,K16564 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 299.0
HFD2_k127_4231061_3 COG1073 Hydrolases of the alpha beta superfamily K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002836 246.0
HFD2_k127_4231061_4 Calcineurin-like phosphoesterase K07313 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000005334 222.0
HFD2_k127_4231061_5 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000009175 159.0
HFD2_k127_4231061_6 - - - - 0.0000000000000000004144 92.0
HFD2_k127_4231061_7 peptidase M13 K07386 - - 0.0000000000000004077 78.0
HFD2_k127_4231061_8 Bacterial aa3 type cytochrome c oxidase subunit IV - - - 0.00009971 50.0
HFD2_k127_4234819_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 3.331e-279 872.0
HFD2_k127_4234819_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.824e-229 717.0
HFD2_k127_4234819_10 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000269 225.0
HFD2_k127_4234819_11 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000001424 214.0
HFD2_k127_4234819_12 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000004862 208.0
HFD2_k127_4234819_13 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000008133 195.0
HFD2_k127_4234819_14 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.00000000000000000000000000000000000000000000119 173.0
HFD2_k127_4234819_15 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 GO:0002790,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.0000000000000000000000000000000000000000006594 162.0
HFD2_k127_4234819_16 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00799 - 2.5.1.18 0.000000000000000000000000000000000000000007241 161.0
HFD2_k127_4234819_17 Protein of unknown function (DUF3088) - - - 0.0000000000000000000000000001012 119.0
HFD2_k127_4234819_18 membrane K08973 - - 0.000000000000000000000000001115 118.0
HFD2_k127_4234819_19 domain, Protein - - - 0.00000000000000000001051 100.0
HFD2_k127_4234819_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008756 505.0
HFD2_k127_4234819_3 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 467.0
HFD2_k127_4234819_4 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005771 393.0
HFD2_k127_4234819_5 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 387.0
HFD2_k127_4234819_6 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 343.0
HFD2_k127_4234819_7 Chromosome partitioning protein ParA K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000003253 233.0
HFD2_k127_4234819_8 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000001732 234.0
HFD2_k127_4234819_9 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000000000000000000000000009513 228.0
HFD2_k127_4281607_0 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 315.0
HFD2_k127_4281607_1 Belongs to the peptidase S41A family - - - 0.000000000000000000000000000000000000000000000000003362 193.0
HFD2_k127_4289459_0 cobalt chelatase K09883 - 6.6.1.2 8.512e-224 709.0
HFD2_k127_4289459_1 TIGRFAM cobalt chelatase, pCobS small subunit K09882 - 6.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 574.0
HFD2_k127_4289459_10 Zincin-like metallopeptidase - - - 0.000000000000000000000000000000000000000000005162 168.0
HFD2_k127_4289459_11 Protein of unknown function (DUF1254) - - - 0.00000000000000000000000000000000000000007415 159.0
HFD2_k127_4289459_12 Protein of unknown function (DUF1214) - - - 0.00000000000000000000000000000000000007108 150.0
HFD2_k127_4289459_13 Cytochrome c - - - 0.0000000000000000000000000000001543 129.0
HFD2_k127_4289459_14 - - - - 0.000000000000000000000000000175 123.0
HFD2_k127_4289459_15 Belongs to the BolA IbaG family K05527,K22066 GO:0006807,GO:0008150,GO:0008152,GO:0010467,GO:0019538,GO:0043170,GO:0044238,GO:0051604,GO:0071704,GO:0097428,GO:0106035,GO:1901564 - 0.00000000000000000000000001262 111.0
HFD2_k127_4289459_16 Rhodanese Homology Domain - - - 0.0000000000000000003013 91.0
HFD2_k127_4289459_17 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000002905 79.0
HFD2_k127_4289459_18 - - - - 0.0000003841 61.0
HFD2_k127_4289459_2 Long-chain fatty aldehyde decarbonylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 540.0
HFD2_k127_4289459_3 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 437.0
HFD2_k127_4289459_4 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 297.0
HFD2_k127_4289459_5 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007279 265.0
HFD2_k127_4289459_6 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000000000000000000002686 194.0
HFD2_k127_4289459_7 PFAM heat shock protein DnaJ domain protein - - - 0.00000000000000000000000000000000000000000000000000174 189.0
HFD2_k127_4289459_8 DNA repair protein MmcB-like - - - 0.0000000000000000000000000000000000000000000001069 171.0
HFD2_k127_4289459_9 Esterase-like activity of phytase - - - 0.0000000000000000000000000000000000000000000001894 181.0
HFD2_k127_4290062_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008488 331.0
HFD2_k127_4290062_1 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000000000000000000000000001059 209.0
HFD2_k127_4290062_2 Transcription elongation factor - - - 0.0000000000000000000000000000000000000000001113 176.0
HFD2_k127_4290062_3 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000000000000002718 169.0
HFD2_k127_4290062_4 O-linked N-acetylglucosamine transferase SPINDLY family - - - 0.000000000000000000000000000000000004152 145.0
HFD2_k127_4290062_5 YCII-related domain - - - 0.00000000000000000000003584 104.0
HFD2_k127_4293174_0 Glycosyltransferase like family 2 K07011 - - 0.00000000000000000000000006387 112.0
HFD2_k127_4293174_1 O-Antigen ligase - - - 0.00000000005753 74.0
HFD2_k127_4326375_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 1.913e-211 682.0
HFD2_k127_4326375_1 M13 family peptidase K01415,K07386 - 3.4.24.71 3.685e-208 668.0
HFD2_k127_4326375_11 Integrase - - - 0.00000136 50.0
HFD2_k127_4326375_12 Domain of unknown function (DUF4279) - - - 0.00005736 46.0
HFD2_k127_4326375_2 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 351.0
HFD2_k127_4326375_3 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003397 259.0
HFD2_k127_4326375_4 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000003512 241.0
HFD2_k127_4326375_5 signal transduction protein with a C-terminal ATPase domain K08082 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000001747 213.0
HFD2_k127_4326375_6 LytTr DNA-binding domain K02477 - - 0.0000000000000000000000000000000000000000000000000000001482 204.0
HFD2_k127_4326375_7 Zn-ribbon-containing protein involved in phosphonate metabolism K06193 - - 0.000000000000000000000000000000000000000000000000009463 181.0
HFD2_k127_4326375_8 COG NOG14600 non supervised orthologous group - - - 0.0000000000000000000000000000002503 123.0
HFD2_k127_4326375_9 PFAM Glycosyl transferase, group 1 K08256 GO:0000026,GO:0000030,GO:0000287,GO:0003674,GO:0003824,GO:0004376,GO:0004377,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006644,GO:0006650,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0019637,GO:0043167,GO:0043169,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046486,GO:0046488,GO:0046872,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.345 0.00000003063 65.0
HFD2_k127_4337256_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 1.057e-220 691.0
HFD2_k127_4337256_1 Amidohydrolase family K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007262 507.0
HFD2_k127_4337256_2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines K01479,K01480 - 3.5.3.11,3.5.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 336.0
HFD2_k127_4337256_3 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.00000000000000000000000000000000000002332 151.0
HFD2_k127_4337256_4 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000000000000000000000000003124 112.0
HFD2_k127_4362208_0 Short-chain dehydrogenase reductase sdr - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007386 395.0
HFD2_k127_4362208_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000309 226.0
HFD2_k127_4362208_2 TPR repeat - - - 0.000000000000003262 87.0
HFD2_k127_439466_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 561.0
HFD2_k127_439466_1 Diguanylate phosphodiesterase K13593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 370.0
HFD2_k127_439466_2 Hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 312.0
HFD2_k127_439466_3 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins K22479 - - 0.00000000000000000000000000000000000000000000001895 177.0
HFD2_k127_439466_4 Phosphoribulokinase / Uridine kinase family K00876 - 2.7.1.48 0.000000000000000000000000000000000000000000009743 173.0
HFD2_k127_439466_5 YjbR - - - 0.00000000000000000000000000008768 118.0
HFD2_k127_4463690_0 Adenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008665 589.0
HFD2_k127_4463690_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 567.0
HFD2_k127_4463690_10 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104,K03741 - 1.20.4.1,3.1.3.48 0.0000000000000000000000000000000000007778 143.0
HFD2_k127_4463690_11 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000000000001209 136.0
HFD2_k127_4463690_12 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000000000000302 85.0
HFD2_k127_4463690_2 Cysteine synthase K01738 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004598 470.0
HFD2_k127_4463690_3 exodeoxyribonuclease III K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 348.0
HFD2_k127_4463690_4 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003364 314.0
HFD2_k127_4463690_5 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000001071 257.0
HFD2_k127_4463690_6 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000000000000000002286 232.0
HFD2_k127_4463690_7 Ribonuclease E/G family - - - 0.0000000000000000000000000000000000000000000000000000000004057 215.0
HFD2_k127_4463690_8 Belongs to the UPF0262 family - - - 0.00000000000000000000000000000000000000000000000000004414 191.0
HFD2_k127_4463690_9 Protein of unknown function (DUF2948) - - - 0.0000000000000000000000000000000000001549 146.0
HFD2_k127_4486906_0 Belongs to the flagella basal body rod proteins family K02396 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 455.0
HFD2_k127_4486906_1 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02397 - - 0.00000000000000000008307 100.0
HFD2_k127_4486906_2 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000007035 78.0
HFD2_k127_4489281_0 COG0861 Membrane protein TerC, possibly involved in tellurium resistance - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005126 329.0
HFD2_k127_4489281_1 D-ala-D-ala dipeptidase K08641 - 3.4.13.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000007287 274.0
HFD2_k127_4489281_2 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000003352 210.0
HFD2_k127_4489281_3 Uncharacterised protein family UPF0066 - - - 0.00000000000000000000000000000000000000000000000000008313 190.0
HFD2_k127_4489281_4 Domain of unknown function (DUF1330) - - - 0.000000000000000000000000002089 115.0
HFD2_k127_4489281_5 - - - - 0.0000007834 58.0
HFD2_k127_4489281_6 Domain of unknown function (DUF4440) - - - 0.0002238 52.0
HFD2_k127_4489281_7 - - - - 0.0003457 48.0
HFD2_k127_449501_0 4-hydroxyphenylpyruvate dioxygenase K00457 - 1.13.11.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 556.0
HFD2_k127_449501_1 Fumarylacetoacetate (FAA) hydrolase family K16171 - 3.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008253 517.0
HFD2_k127_449501_10 - - - - 0.00000005012 58.0
HFD2_k127_449501_2 Isoaspartyl peptidase K13051 - 3.4.19.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000633 423.0
HFD2_k127_449501_3 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 351.0
HFD2_k127_449501_4 COG0346 Lactoylglutathione lyase and related lyases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 298.0
HFD2_k127_449501_5 Glutathione S-transferase, N-terminal domain K01800,K01801 - 5.2.1.2,5.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000184 250.0
HFD2_k127_449501_6 Peptidase M50 - - - 0.000000000000000000000000000000000000000000000000002342 195.0
HFD2_k127_449501_7 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000008014 151.0
HFD2_k127_449501_8 MarR family transcriptional regulator - - - 0.0000000000000000000000000000000000004817 145.0
HFD2_k127_449501_9 - - - - 0.000000000005178 67.0
HFD2_k127_4515862_0 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000341 284.0
HFD2_k127_4515862_1 - K01992 - - 0.000000000000000000000000000000000000000002858 167.0
HFD2_k127_4515862_2 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000193 104.0
HFD2_k127_4528024_0 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941,K18824 GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15,2.7.6.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003552 291.0
HFD2_k127_4528024_1 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000009885 239.0
HFD2_k127_4528024_2 Belongs to the Nudix hydrolase family - - - 0.0000000000000000000000000000000000000000000000001374 183.0
HFD2_k127_4528024_3 PFAM regulatory protein LuxR - - - 0.0000000000000000000000000000000157 129.0
HFD2_k127_4528024_4 Protein of unknown function (DUF4199) - - - 0.00000000001305 69.0
HFD2_k127_4538448_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 4.277e-225 720.0
HFD2_k127_4538448_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 361.0
HFD2_k127_4538448_2 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 323.0
HFD2_k127_4538448_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004114 312.0
HFD2_k127_4538448_4 Asp/Glu/Hydantoin racemase K01779 - 5.1.1.13 0.000000000000000000000000000000000007761 144.0
HFD2_k127_4538448_5 Tetratricopeptide repeats - - - 0.00005622 56.0
HFD2_k127_4560747_0 COG1668 ABC-type Na efflux pump, permease component K01992 - - 0.0000000000000000000000000000000000000000000000000000000001546 218.0
HFD2_k127_4560747_1 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000004854 169.0
HFD2_k127_4560747_2 COQ9 K18587 - - 0.000000000000000000000000000000000000000000004911 172.0
HFD2_k127_4560747_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000007015 156.0
HFD2_k127_4560747_4 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000000003885 149.0
HFD2_k127_4560747_5 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00000000000000000000000000000634 122.0
HFD2_k127_4560747_6 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000005235 112.0
HFD2_k127_4560747_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0004482 48.0
HFD2_k127_456870_0 Peptidase family M48 - - - 0.00000000000000000000000000000000000002927 156.0
HFD2_k127_456870_1 - - - - 0.0000000000000000001885 97.0
HFD2_k127_456870_2 biosynthesis protein - - - 0.0000000000003669 81.0
HFD2_k127_4598213_0 COG0524 Sugar kinases, ribokinase family K00847,K00856 - 2.7.1.20,2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 370.0
HFD2_k127_4598213_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008631 297.0
HFD2_k127_4598213_2 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000008697 256.0
HFD2_k127_4598213_3 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000001667 199.0
HFD2_k127_4598213_4 COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) - - - 0.000000000000000000000000000000001785 141.0
HFD2_k127_4598213_5 Integral membrane protein (DUF2244) - - - 0.000000000000000000000000002096 118.0
HFD2_k127_4605652_0 Haloacid dehalogenase K17686 - 3.6.3.54 4.02e-319 993.0
HFD2_k127_4605652_1 copper resistance - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 520.0
HFD2_k127_4605652_10 copper resistance protein K07245 - - 0.000000000003756 71.0
HFD2_k127_4605652_11 - - - - 0.00000002088 65.0
HFD2_k127_4605652_2 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002837 487.0
HFD2_k127_4605652_3 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 434.0
HFD2_k127_4605652_4 Ankyrin repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000008953 242.0
HFD2_k127_4605652_5 - - - - 0.0000000000000000000000000000000000000000000000000004132 189.0
HFD2_k127_4605652_6 Penicillinase repressor - - - 0.00000000000000000000000000000000000000002274 155.0
HFD2_k127_4605652_7 lysozyme K01185 - 3.2.1.17 0.000000000000000000000000000000000000002103 161.0
HFD2_k127_4605652_8 Metal-sensitive transcriptional repressor K21600 - - 0.00000000000000000000000000006084 121.0
HFD2_k127_4605652_9 Protein of unknwon function (DUF3008) - - - 0.0000000000000000004593 89.0
HFD2_k127_4614575_0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) K01809 - 5.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005607 402.0
HFD2_k127_4614575_1 Belongs to the mannose-6-phosphate isomerase type 2 family K00971 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 358.0
HFD2_k127_4614575_2 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000001657 234.0
HFD2_k127_4614575_3 PFAM NAD-dependent epimerase dehydratase K08679 - 5.1.3.6 0.0000000000000000000000000000000000000000000000000004328 186.0
HFD2_k127_4615334_0 Amidohydrolase family K06015 - 3.5.1.81 1.894e-221 700.0
HFD2_k127_4615334_1 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000004591 221.0
HFD2_k127_4615334_2 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 GO:0003674,GO:0003824,GO:0004057,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016598,GO:0016740,GO:0016746,GO:0016755,GO:0019538,GO:0019941,GO:0030163,GO:0036211,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 2.3.2.29 0.0004217 42.0
HFD2_k127_4616989_0 ammonium transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 504.0
HFD2_k127_4616989_1 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003242 249.0
HFD2_k127_4661292_0 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 - 2.7.1.25,2.7.7.4 5.125e-304 947.0
HFD2_k127_4661292_1 Sulfate adenylyltransferase K00957 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004513 533.0
HFD2_k127_4661292_10 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000005159 205.0
HFD2_k127_4661292_11 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000000000004661 196.0
HFD2_k127_4661292_12 Belongs to the ArsC family K00537 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.20.4.1 0.0000000000000000000000000000000000000000000000000000009698 197.0
HFD2_k127_4661292_13 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000009968 198.0
HFD2_k127_4661292_14 Activator of Hsp90 ATPase - - - 0.00000000000000000000000000000000000000000001201 166.0
HFD2_k127_4661292_15 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000006871 158.0
HFD2_k127_4661292_16 - - - - 0.000000000000000000000000000000000001191 142.0
HFD2_k127_4661292_17 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000001561 144.0
HFD2_k127_4661292_18 Tetratricopeptide repeat-like domain - - - 0.00000000000007136 80.0
HFD2_k127_4661292_19 - - - - 0.000000002143 63.0
HFD2_k127_4661292_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 426.0
HFD2_k127_4661292_20 - - - - 0.00000005098 60.0
HFD2_k127_4661292_3 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 389.0
HFD2_k127_4661292_4 PFAM Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 371.0
HFD2_k127_4661292_5 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005062 354.0
HFD2_k127_4661292_6 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 308.0
HFD2_k127_4661292_7 hydrolase of the alpha beta-hydrolase fold K07020 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001008 287.0
HFD2_k127_4661292_8 glycosylase i K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001875 272.0
HFD2_k127_4661292_9 PFAM Glutathione S-transferase domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000307 229.0
HFD2_k127_4703483_0 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 332.0
HFD2_k127_4703483_1 AMP-binding enzyme K08746,K08749 - 6.2.1.3 0.0000000000000000000000000000000000000008786 151.0
HFD2_k127_473756_0 Glutathione S-transferase, C-terminal domain K11209 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 324.0
HFD2_k127_473756_1 CoA-binding domain K03606,K20997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 299.0
HFD2_k127_473756_2 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.00000000000000000001116 96.0
HFD2_k127_473756_3 biopolymer transport protein K03559,K03560 - - 0.000000000001197 74.0
HFD2_k127_4740312_0 leukotriene A-4 hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006541 477.0
HFD2_k127_47869_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951,K01139 - 2.7.6.5,3.1.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003024 503.0
HFD2_k127_47869_1 NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007197 267.0
HFD2_k127_47869_2 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000000000001873 130.0
HFD2_k127_47869_3 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.000000000000000000000000000007585 124.0
HFD2_k127_47869_4 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000001979 111.0
HFD2_k127_4801107_0 Phosphoglucomutase K15778 - 5.4.2.2,5.4.2.8 1.685e-247 777.0
HFD2_k127_4801107_1 Male sterility protein K08678 - 4.1.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 530.0
HFD2_k127_4801107_2 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000652 484.0
HFD2_k127_4801107_3 UDP-glucose 4-epimerase K01784,K12448 - 5.1.3.2,5.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008128 442.0
HFD2_k127_4801107_4 DAHP synthetase I family K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009724 399.0
HFD2_k127_4801107_5 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 - 5.4.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009462 368.0
HFD2_k127_4801107_6 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000003306 247.0
HFD2_k127_4801107_7 LysR substrate binding domain K03566 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002452 248.0
HFD2_k127_4801107_8 Cytidine and deoxycytidylate deaminase zinc-binding region K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000003029 154.0
HFD2_k127_4801107_9 Pfam SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000001545 148.0
HFD2_k127_4810992_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 586.0
HFD2_k127_4810992_1 N-carbamoylputrescine amidase K12251 - 3.5.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 465.0
HFD2_k127_4810992_10 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0000000000000000000000000000000000000008306 153.0
HFD2_k127_4810992_11 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.00000000000000000000000000000007895 130.0
HFD2_k127_4810992_13 Superinfection immunity protein - - - 0.0000001568 54.0
HFD2_k127_4810992_15 Membrane-bound lysozyme-inhibitor of c-type lysozyme - - - 0.00001574 54.0
HFD2_k127_4810992_16 Thioredoxin K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.0002804 50.0
HFD2_k127_4810992_2 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 425.0
HFD2_k127_4810992_3 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004482 411.0
HFD2_k127_4810992_4 asparaginase K13051 - 3.4.19.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 313.0
HFD2_k127_4810992_5 dithiol-disulfide isomerase involved in polyketide biosynthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000138 258.0
HFD2_k127_4810992_6 rrna methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000006813 243.0
HFD2_k127_4810992_7 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000006477 238.0
HFD2_k127_4810992_8 COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000000001076 234.0
HFD2_k127_4810992_9 nuclear chromosome segregation - - - 0.0000000000000000000000000000000000000001021 162.0
HFD2_k127_4815955_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 4.041e-319 990.0
HFD2_k127_4815955_1 amino acid peptide transporter K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008427 490.0
HFD2_k127_4815955_10 Bacterial protein of unknown function (Gcw_chp) - - - 0.000004496 57.0
HFD2_k127_4815955_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000111 258.0
HFD2_k127_4815955_3 COG0822 NifU homolog involved in Fe-S cluster formation - - - 0.0000000000000000000000000000000000000000000000000002446 188.0
HFD2_k127_4815955_4 Belongs to the globin family K05916 - 1.14.12.17 0.0000000000000000000000000000000001958 137.0
HFD2_k127_4815955_5 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000001618 115.0
HFD2_k127_4815955_6 YjbR - - - 0.00000000000000000000000002834 112.0
HFD2_k127_4815955_7 Essential cell division protein K03589 - - 0.000000000000000000001028 98.0
HFD2_k127_4815955_8 Glycosyl transferase family 2 K07011 - - 0.0000000000000005515 83.0
HFD2_k127_4815955_9 - - - - 0.000000003035 63.0
HFD2_k127_4816033_0 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 GO:0005575,GO:0005623,GO:0009288,GO:0009425,GO:0042597,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 460.0
HFD2_k127_4816033_1 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.00000000000000000000000000000000000000000000000000000000005376 207.0
HFD2_k127_4816033_2 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.00000000000000000000000000003067 119.0
HFD2_k127_4816033_3 Rod binding protein - - - 0.00000000000000000001361 96.0
HFD2_k127_4816033_4 - - - - 0.000000000000000006223 89.0
HFD2_k127_4816033_5 - - - - 0.000000000000004587 88.0
HFD2_k127_4816033_6 Class II flagellar assembly regulator - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000001507 59.0
HFD2_k127_4816033_7 Predicted membrane protein (DUF2214) K08983 - - 0.0002932 45.0
HFD2_k127_4817600_0 Beta-glucosidase K05350 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007499 597.0
HFD2_k127_4817600_1 Rossmann fold nucleotide-binding protein involved in DNA uptake K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 338.0
HFD2_k127_4817600_2 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000001178 223.0
HFD2_k127_4817600_3 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000008691 196.0
HFD2_k127_4872053_0 ErfK YbiS YcfS YnhG - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003056 299.0
HFD2_k127_4872053_1 Bacterial protein of unknown function (DUF882) - - - 0.0000000000000000000000000000000000005506 141.0
HFD2_k127_4923919_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 313.0
HFD2_k127_4923919_1 May be involved in the biosynthesis of molybdopterin K03638 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0042802,GO:0044424,GO:0044444,GO:0044464 2.7.7.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004042 276.0
HFD2_k127_4923919_2 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000002885 225.0
HFD2_k127_4923919_3 Transport of potassium into the cell K03549 - - 0.00000000000000000000000000000000000000000000000000000005321 200.0
HFD2_k127_4923919_4 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000001755 184.0
HFD2_k127_4923919_5 Molybdopterin K03635 - 2.8.1.12 0.00000000000000000000000000001488 126.0
HFD2_k127_4923919_6 Molybdopterin converting factor, small subunit K03636 - - 0.0000000000000003553 81.0
HFD2_k127_4932304_0 carboxylase K01965,K01968 - 6.4.1.3,6.4.1.4 3.162e-245 773.0
HFD2_k127_4932304_1 carboxyl transferase K01969 - 6.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008432 290.0
HFD2_k127_4932304_2 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004341 280.0
HFD2_k127_4932304_3 Protein of unknown function (DUF2785) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007205 254.0
HFD2_k127_4932304_4 COG1335 Amidases related to nicotinamidase - - - 0.0000000000000000000000000000000000000000000000000000000000007194 216.0
HFD2_k127_4932304_5 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - 0.00000000000000000000000000000000000000000000000000000004987 205.0
HFD2_k127_4932304_6 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.000000000000000000000000000000000000000000000000000005234 194.0
HFD2_k127_4932304_7 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) K02806 - - 0.00000000000000000000000000000000000003611 149.0
HFD2_k127_4932304_8 PFAM Bacterial transferase hexapeptide (three repeats) - - - 0.0000000000000000000000000000000007053 138.0
HFD2_k127_4932304_9 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0000000000000000001041 96.0
HFD2_k127_4982387_0 carboxylase K01965 - 6.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005674 597.0
HFD2_k127_4982387_1 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003648 367.0
HFD2_k127_4982387_2 beta' subunit K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000004671 254.0
HFD2_k127_4982387_3 - - - - 0.000000000000000000000000000000000000000000001483 174.0
HFD2_k127_4982387_4 - - - - 0.0000000016 64.0
HFD2_k127_5009147_0 Rieske 2Fe-2S - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007222 422.0
HFD2_k127_5009147_1 peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001003 274.0
HFD2_k127_5009147_2 Cysteine dioxygenase type I - - - 0.000000000000000000000000000000000000000000000000000000000000000001658 231.0
HFD2_k127_5009147_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000001333 218.0
HFD2_k127_5009147_4 Belongs to the UPF0178 family K09768 - - 0.000000000000000000000000000000000000000000000000000007234 194.0
HFD2_k127_5009147_5 COG1560 Lauroyl myristoyl acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000003381 150.0
HFD2_k127_5009147_6 COG0500 SAM-dependent methyltransferases - - - 0.000000000000000000000000000000000004824 153.0
HFD2_k127_5009147_7 -acetyltransferase - - - 0.000000000000000000000000009257 115.0
HFD2_k127_5009147_8 Uncharacterized protein conserved in bacteria (DUF2093) - - - 0.00000000000000000002236 92.0
HFD2_k127_5011779_0 Angiotensin-converting enzyme K01283 - 3.4.15.1 5.54e-248 779.0
HFD2_k127_5011779_1 differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs K16872 - 2.3.1.207 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 519.0
HFD2_k127_5011779_10 (LPS) heptosyltransferase - - - 0.00000006541 59.0
HFD2_k127_5011779_11 - - - - 0.0001992 53.0
HFD2_k127_5011779_2 belongs to the nudix hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004086 374.0
HFD2_k127_5011779_3 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 297.0
HFD2_k127_5011779_4 Metal dependent phosphohydrolases with conserved 'HD' motif. K06952 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008031 275.0
HFD2_k127_5011779_5 Belongs to the GcvT family K06980 - - 0.000000000000000000000000000000000000000000000000000006138 203.0
HFD2_k127_5011779_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000003293 186.0
HFD2_k127_5011779_7 protein tyrosine phosphatase - - - 0.00000000000000000000000000000000000000005638 157.0
HFD2_k127_5011779_8 AntiSigma factor - - - 0.0000000000000000000000000000002443 138.0
HFD2_k127_5011779_9 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000003832 69.0
HFD2_k127_5034644_0 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.4 6.881e-219 687.0
HFD2_k127_5034644_1 Aas bifunctional protein K05939 - 2.3.1.40,6.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 571.0
HFD2_k127_5034644_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 493.0
HFD2_k127_5034644_3 O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 501.0
HFD2_k127_5034644_4 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 376.0
HFD2_k127_5034644_5 UPF0056 membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000000000000000000001661 229.0
HFD2_k127_5034644_6 Belongs to the CinA family K03743 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000002179 192.0
HFD2_k127_5034644_7 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000003393 143.0
HFD2_k127_5034644_8 cyclase dehydrase K18588 - - 0.000000000000000000000000002341 116.0
HFD2_k127_5044619_0 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001972 268.0
HFD2_k127_5044619_1 protein conserved in bacteria - - - 0.000000000000000000000000000000000002595 143.0
HFD2_k127_5044619_2 protein conserved in bacteria - - - 0.00000000000000000000000000000003469 131.0
HFD2_k127_5084764_0 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 439.0
HFD2_k127_5084764_1 AFG1 family ATPase K06916 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0006091,GO:0006119,GO:0006123,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007005,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0017144,GO:0019538,GO:0019637,GO:0019646,GO:0019693,GO:0022900,GO:0022904,GO:0030163,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0035694,GO:0042773,GO:0042775,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071840,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 420.0
HFD2_k127_5084764_2 Acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004084 325.0
HFD2_k127_5084764_3 Acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000001409 222.0
HFD2_k127_5084764_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000003291 145.0
HFD2_k127_5084764_5 TIGRFAM anti-sigma factor, , ChrR family K07167 - - 0.000000000000000000000000000000001366 138.0
HFD2_k127_5084764_6 Periplasmic component of the Tol biopolymer transport system - - - 0.000000000000000000000002762 108.0
HFD2_k127_5084764_7 - - - - 0.000000000000000000000002938 104.0
HFD2_k127_5098736_0 Transport of potassium into the cell K03549 - - 3.632e-230 731.0
HFD2_k127_5098736_1 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003383 302.0
HFD2_k127_5098736_2 PFAM surface antigen K07278 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001771 293.0
HFD2_k127_5098736_3 Prolyl 4-hydroxylase alpha subunit homologues. K00472 - 1.14.11.2 0.000000000000000000000000000000000000000000005688 172.0
HFD2_k127_5098736_4 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000000000000000000009102 131.0
HFD2_k127_5098736_5 Protein of unknown function (DUF1674) - - - 0.000000000000155 78.0
HFD2_k127_5116537_0 Belongs to the AdoMet synthase family K00789 - 2.5.1.6 1.263e-205 646.0
HFD2_k127_5116537_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 591.0
HFD2_k127_5116537_10 Predicted membrane protein (DUF2306) - - - 0.00000000000000000000000000000000000000000000000000001252 196.0
HFD2_k127_5116537_11 Transcriptional regulator - - - 0.000000000000000000000000000000004873 132.0
HFD2_k127_5116537_12 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000000001826 131.0
HFD2_k127_5116537_13 - - - - 0.0000000000004358 72.0
HFD2_k127_5116537_14 - - - - 0.000000000001807 73.0
HFD2_k127_5116537_15 Protein of unknown function (DUF1211) - - - 0.00000546 48.0
HFD2_k127_5116537_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0030060,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003508 523.0
HFD2_k127_5116537_3 Peptidase M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005101 471.0
HFD2_k127_5116537_4 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003908 368.0
HFD2_k127_5116537_5 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002781 289.0
HFD2_k127_5116537_6 COG1253 Hemolysins and related proteins containing CBS domains K06189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009271 272.0
HFD2_k127_5116537_7 LytTr DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001322 244.0
HFD2_k127_5116537_8 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.0000000000000000000000000000000000000000000000000000000000000000001062 234.0
HFD2_k127_5116537_9 O-methyltransferase K00588 - 2.1.1.104 0.000000000000000000000000000000000000000000000000000000000000000001094 233.0
HFD2_k127_5121735_0 receptor - - - 4.111e-275 869.0
HFD2_k127_5121735_1 COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component K09014 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009536,GO:0009842,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 - 6.232e-259 808.0
HFD2_k127_5121735_10 COG1104 Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006643 309.0
HFD2_k127_5121735_11 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004262 297.0
HFD2_k127_5121735_12 Alpha beta hydrolase K07018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 291.0
HFD2_k127_5121735_13 COG2199 FOG GGDEF domain K07216,K13590 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 295.0
HFD2_k127_5121735_14 COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component K09015 - - 0.000000000000000000000000000000000000000000000000000000000000753 220.0
HFD2_k127_5121735_15 Belongs to the HesB IscA family K13628 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009058,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0018130,GO:0019438,GO:0019538,GO:0022607,GO:0031163,GO:0031974,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0051604,GO:0070013,GO:0071704,GO:0071840,GO:0097428,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000006442 185.0
HFD2_k127_5121735_16 FeS assembly SUF system protein - - - 0.00000000000000000000000000000000000000000000000002709 184.0
HFD2_k127_5121735_17 transcriptional regulator K13643 - - 0.00000000000000000000000000000000000000000000008919 172.0
HFD2_k127_5121735_18 TfoX N-terminal domain K07343 - - 0.00000000000000000000000000001467 124.0
HFD2_k127_5121735_19 protein conserved in bacteria - - - 0.000000000000000000000000002113 122.0
HFD2_k127_5121735_2 COG0457 FOG TPR repeat - - - 1.006e-223 711.0
HFD2_k127_5121735_20 Domain of unknown function (DUF4167) - - - 0.000000000000000000000001718 112.0
HFD2_k127_5121735_21 - - - - 0.0000000000008904 74.0
HFD2_k127_5121735_22 - - - - 0.00000008229 64.0
HFD2_k127_5121735_3 belongs to the aldehyde dehydrogenase family K00154,K22445 - 1.2.1.68,1.2.99.10 1.631e-214 679.0
HFD2_k127_5121735_4 Belongs to the PEP-utilizing enzyme family K08484 - 2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 591.0
HFD2_k127_5121735_5 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004527 576.0
HFD2_k127_5121735_6 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009809 527.0
HFD2_k127_5121735_7 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007954 455.0
HFD2_k127_5121735_8 FeS assembly ATPase SufC K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006283 363.0
HFD2_k127_5121735_9 PFAM Enoyl-CoA hydratase isomerase K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 325.0
HFD2_k127_5158980_0 3-hydroxyacyl-CoA dehydrogenase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 2.501e-300 938.0
HFD2_k127_5158980_1 MAPEG family - - - 0.00000000000000000000000000000000000000000000000002018 183.0
HFD2_k127_5158980_2 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000004242 167.0
HFD2_k127_5158980_3 YCII-related domain - - - 0.00000000000000001398 90.0
HFD2_k127_5158980_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000004174 72.0
HFD2_k127_5158980_5 - - - - 0.0000000002748 70.0
HFD2_k127_5160284_0 PFAM thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000001495 180.0
HFD2_k127_5160284_1 thioesterase - - - 0.000000000000000000000000000000000000000002148 160.0
HFD2_k127_5160284_2 PFAM Exopolysaccharide synthesis ExoD - - - 0.00000000000000000000000000000000000000000846 162.0
HFD2_k127_5160284_3 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000004804 134.0
HFD2_k127_5165474_0 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family K09461 - 1.14.13.40 0.0 1039.0
HFD2_k127_5165474_1 Involved in type III protein export during flagellum assembly K02412 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008025 543.0
HFD2_k127_5165474_10 PFAM secretion protein HlyD family protein K03543 - - 0.000000000000000000000000000000000000000000000000000000000000000002814 248.0
HFD2_k127_5165474_2 Major facilitator superfamily K03446 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 499.0
HFD2_k127_5165474_3 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483,K13584 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 425.0
HFD2_k127_5165474_4 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 394.0
HFD2_k127_5165474_5 RND efflux system, outer membrane lipoprotein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009665 368.0
HFD2_k127_5165474_6 ABC transporter K02003,K05685 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 346.0
HFD2_k127_5165474_7 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005657 344.0
HFD2_k127_5165474_8 Belongs to the short-chain dehydrogenases reductases (SDR) family K00019,K07535 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000003136 267.0
HFD2_k127_5165474_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004721 267.0
HFD2_k127_5166555_0 ABC-type multidrug transport system, ATPase and permease K06147,K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006479 507.0
HFD2_k127_5166555_1 Putative modulator of DNA gyrase K03592 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 418.0
HFD2_k127_5166555_2 Ribosomal protein L11 methyltransferase (PrmA) - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010565,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018022,GO:0018023,GO:0018193,GO:0018205,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031329,GO:0031330,GO:0031974,GO:0031998,GO:0031999,GO:0032259,GO:0036211,GO:0043086,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043414,GO:0043467,GO:0044092,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045833,GO:0045922,GO:0046320,GO:0046322,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0050994,GO:0050995,GO:0051341,GO:0051354,GO:0062012,GO:0062014,GO:0065007,GO:0065009,GO:0070013,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1904732,GO:1904733,GO:1904735,GO:1904736 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006304 270.0
HFD2_k127_5166555_3 Belongs to the inositol monophosphatase superfamily K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000446 220.0
HFD2_k127_5166555_4 - - - - 0.00000000000000000000000000003572 123.0
HFD2_k127_5166555_5 Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000003994 116.0
HFD2_k127_5166555_6 relative of glutathione S-transferase, MAPEG superfamily K07136 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000001317 104.0
HFD2_k127_5167491_0 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000138 268.0
HFD2_k127_5167491_1 TonB dependent receptor - - - 0.000000000000000000009764 96.0
HFD2_k127_5167491_2 YjbR - - - 0.000000001183 64.0
HFD2_k127_5167511_0 NUDIX domain - - - 0.000000000000000000000000000000000000000000006119 167.0
HFD2_k127_5167511_1 - - - - 0.000000000000000000000000000000000000004244 149.0
HFD2_k127_5167511_2 Ion channel - - - 0.000000000000000000000000000000000001426 144.0
HFD2_k127_5167511_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000278 81.0
HFD2_k127_5167511_4 STAS domain K03321 - - 0.0000543 48.0
HFD2_k127_518638_0 HpcH/HpaI aldolase/citrate lyase family K08691 GO:0003674,GO:0003824,GO:0005488,GO:0016829,GO:0016830,GO:0016833,GO:0043167,GO:0043169,GO:0046872,GO:0047777,GO:0050083 4.1.3.24,4.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 542.0
HFD2_k127_518638_1 PFAM peptidase M19 renal dipeptidase K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005325 470.0
HFD2_k127_518638_10 - - - - 0.000000000000000000000008988 106.0
HFD2_k127_518638_11 Domain of unknown function (DUF4142) K08995 - - 0.000007319 55.0
HFD2_k127_518638_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 438.0
HFD2_k127_518638_3 FAD-NAD(P)-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 324.0
HFD2_k127_518638_4 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000000000000002379 200.0
HFD2_k127_518638_5 Tol-pal system-associated acyl-CoA thioesterase K07107 - - 0.00000000000000000000000000000000000000000000000000000006388 199.0
HFD2_k127_518638_6 Pyridoxamine 5'-phosphate oxidase like - - - 0.0000000000000000000000000000000000000000000001607 176.0
HFD2_k127_518638_7 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000003359 160.0
HFD2_k127_518638_8 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000003308 160.0
HFD2_k127_518638_9 COG0811 Biopolymer transport proteins K03562 - - 0.0000000000000000000000000000000000001642 147.0
HFD2_k127_5202940_0 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 418.0
HFD2_k127_5202940_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005095 349.0
HFD2_k127_5202940_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000281 317.0
HFD2_k127_5202940_3 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000001422 222.0
HFD2_k127_5202940_4 - - - - 0.0007801 47.0
HFD2_k127_5255508_0 enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 324.0
HFD2_k127_5255508_1 UbiA prenyltransferase family - - - 0.00000000000000000000000000000000000000000000000000003224 197.0
HFD2_k127_5255508_2 - - - - 0.00000000000000000000000000004949 126.0
HFD2_k127_5282567_0 Saccharopine dehydrogenase NADP binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004811 373.0
HFD2_k127_5282567_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004642 278.0
HFD2_k127_5282567_2 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007304 250.0
HFD2_k127_5282567_3 Barstar (barnase inhibitor) - - - 0.00000000000005151 81.0
HFD2_k127_5285754_0 Mg chelatase subunit ChlI K07391 - - 1.271e-203 646.0
HFD2_k127_5285754_1 major facilitator superfamily K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 621.0
HFD2_k127_5285754_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 376.0
HFD2_k127_5306144_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1020.0
HFD2_k127_5306144_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008243 437.0
HFD2_k127_5306144_10 - - - - 0.0000000000000000000000000000000000001451 147.0
HFD2_k127_5306144_11 Putative prokaryotic signal transducing protein - - - 0.0004131 46.0
HFD2_k127_5306144_2 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003927 415.0
HFD2_k127_5306144_3 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 395.0
HFD2_k127_5306144_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005371 360.0
HFD2_k127_5306144_5 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000002751 231.0
HFD2_k127_5306144_6 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000000000007198 184.0
HFD2_k127_5306144_7 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000001594 165.0
HFD2_k127_5306144_8 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000000000000002905 154.0
HFD2_k127_5306144_9 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000005249 146.0
HFD2_k127_5359934_0 AcrB/AcrD/AcrF family - - - 9.214e-270 863.0
HFD2_k127_5359934_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003783 574.0
HFD2_k127_5359934_2 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily K15270 - - 0.0000000000000000000000000000000000000000000003764 178.0
HFD2_k127_5359934_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000005106 170.0
HFD2_k127_5359934_4 Outer membrane efflux protein - - - 0.00000000000000000000000001408 121.0
HFD2_k127_5359934_5 transcriptional regulator K16138 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000002901 108.0
HFD2_k127_5359934_6 Family of unknown function (DUF5367) - - - 0.000000001508 65.0
HFD2_k127_5398677_0 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005317 489.0
HFD2_k127_5398677_1 Peptidase family S58 - - - 0.00000000000000001473 89.0
HFD2_k127_5398677_2 Signal transduction histidine kinase - - - 0.000000001093 60.0
HFD2_k127_5420045_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 0.0 1293.0
HFD2_k127_5420045_1 ABC-type uncharacterized transport system K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005228 419.0
HFD2_k127_5420045_2 ABC transporter permease K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005309 306.0
HFD2_k127_5420045_3 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000006334 213.0
HFD2_k127_5420045_4 Domain of unknown function (DUF4349) - - - 0.000000000000000000000000000000000000000000000000000002506 203.0
HFD2_k127_5420045_5 Protein of unknown function (DUF1223) - - - 0.00000000000000000000000000000000000002416 153.0
HFD2_k127_5420045_6 Domain of unknown function (DUF4340) - - - 0.000000000000000000000000000000001308 144.0
HFD2_k127_5420045_7 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.000000000000000443 83.0
HFD2_k127_5420867_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1162.0
HFD2_k127_5420867_1 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004586 476.0
HFD2_k127_5420867_2 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000374 380.0
HFD2_k127_5420867_3 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000001034 231.0
HFD2_k127_5420867_4 Universal stress protein - - - 0.0000000000000000000000000000000000000000000000000000004938 205.0
HFD2_k127_5420867_5 - - - - 0.0000000000000002032 86.0
HFD2_k127_5448718_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003966 516.0
HFD2_k127_5448718_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 403.0
HFD2_k127_5448718_2 response to cobalt ion - GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0010045,GO:0010243,GO:0030288,GO:0030313,GO:0031975,GO:0032025,GO:0033554,GO:0042221,GO:0042597,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:1901652,GO:1901698,GO:1901700 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002192 268.0
HFD2_k127_5448718_3 LTXXQ motif family protein - - - 0.00000000002552 71.0
HFD2_k127_5461302_0 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 406.0
HFD2_k127_5461302_1 Acetoacetyl-CoA reductase K00023 - 1.1.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 372.0
HFD2_k127_5461302_10 CsbD-like - - - 0.0000000000003038 72.0
HFD2_k127_5461302_2 protein conserved in bacteria K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 326.0
HFD2_k127_5461302_3 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000308 319.0
HFD2_k127_5461302_4 adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000003786 242.0
HFD2_k127_5461302_5 Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000276 173.0
HFD2_k127_5461302_6 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.00000000000000000000000000000000000000000000005353 171.0
HFD2_k127_5461302_7 Belongs to the peptidase S1B family - - - 0.00000000000000000000000000000000000000000104 162.0
HFD2_k127_5461302_8 Methyltransferase - - - 0.000000000000000000000000000000000000000001074 166.0
HFD2_k127_5467712_0 Pilus formation protein N terminal region K02280 - - 0.000000000000000000000000000000000000000000000000000000000000002514 224.0
HFD2_k127_5467712_1 Putative Flp pilus-assembly TadE/G-like - - - 0.00000000000000000006341 98.0
HFD2_k127_5512587_0 Glycine cleavage system T protein K00605 GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008483,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0016769,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0032991,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003704 432.0
HFD2_k127_5512587_1 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000001705 204.0
HFD2_k127_5512587_2 Belongs to the FPP GGPP synthase family K02523 GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 2.5.1.90 0.0000000000002033 72.0
HFD2_k127_5522366_0 Cupin superfamily protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000802 399.0
HFD2_k127_5522366_1 COG1834 N-Dimethylarginine dimethylaminohydrolase K01482 - 3.5.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 315.0
HFD2_k127_5522366_2 Belongs to the 'phage' integrase family. XerC subfamily K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 299.0
HFD2_k127_5522366_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 0.0000000000000000000000000000000000000000000000004823 187.0
HFD2_k127_5522366_4 - - - - 0.000000000000000000000000000000000000001389 158.0
HFD2_k127_5522366_5 Domain of unknown function (DUF4198) - - - 0.00000000000000000000000000000000001012 148.0
HFD2_k127_5522366_6 membrane - - - 0.000000000000000002858 89.0
HFD2_k127_5522366_7 PFAM Helix-turn-helix - - - 0.000000000001075 70.0
HFD2_k127_5522366_8 - - - - 0.000001085 60.0
HFD2_k127_5540104_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 2.206e-260 815.0
HFD2_k127_5540104_1 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000002255 132.0
HFD2_k127_5546394_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 9.816e-227 719.0
HFD2_k127_5598799_0 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 484.0
HFD2_k127_5598799_1 Cysteine synthase K01738 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006521 293.0
HFD2_k127_5598799_2 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000888 299.0
HFD2_k127_5598799_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002845 257.0
HFD2_k127_5598799_4 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000003627 96.0
HFD2_k127_5627829_0 Aminotransferase, class V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 542.0
HFD2_k127_5627829_1 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 306.0
HFD2_k127_5627829_2 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006406 288.0
HFD2_k127_5654669_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 9.015e-232 731.0
HFD2_k127_5654669_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 482.0
HFD2_k127_5654669_10 RNase H K03469 - 3.1.26.4 0.0000000000000000000000000141 108.0
HFD2_k127_5654669_11 Uncharacterized protein family UPF0016 - - - 0.0000000000000000007561 89.0
HFD2_k127_5654669_12 - - - - 0.00000000000000222 81.0
HFD2_k127_5654669_13 ribosome binding - - - 0.000003497 51.0
HFD2_k127_5654669_2 Periplasmic copper-binding protein (NosD) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 389.0
HFD2_k127_5654669_3 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003689 343.0
HFD2_k127_5654669_4 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008814 337.0
HFD2_k127_5654669_5 COG4240 Predicted kinase K15918 - 2.7.1.31 0.000000000000000000000000000000000000000000000000000000000000001769 228.0
HFD2_k127_5654669_6 Uncharacterized protein family, UPF0114 - - - 0.0000000000000000000000000000000000000000000000001023 183.0
HFD2_k127_5654669_7 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000147 169.0
HFD2_k127_5654669_8 - - - - 0.00000000000000000000000000000000000000000001661 176.0
HFD2_k127_5654669_9 MAPEG family - - - 0.00000000000000000000000000000000003184 140.0
HFD2_k127_5658907_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 2.203e-315 981.0
HFD2_k127_5658907_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858,K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005572 446.0
HFD2_k127_5658907_10 - - - - 0.0000000000000001536 87.0
HFD2_k127_5658907_2 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004714 280.0
HFD2_k127_5658907_3 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000002415 244.0
HFD2_k127_5658907_4 Riboflavin synthase K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000006802 231.0
HFD2_k127_5658907_5 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000209 170.0
HFD2_k127_5658907_6 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000003374 146.0
HFD2_k127_5658907_7 RibD C-terminal domain K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000002676 138.0
HFD2_k127_5658907_8 PFAM SmpA OmlA - - - 0.0000000000000000000000000006711 124.0
HFD2_k127_5658907_9 Ubiquinol-cytochrome C chaperone K17662 - - 0.000000000000000000000000003031 117.0
HFD2_k127_5666339_0 carboxyl transferase K01969 - 6.4.1.4 2.119e-288 891.0
HFD2_k127_5666339_1 Dehydrogenase K00253 - 1.3.8.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 465.0
HFD2_k127_5666339_2 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0000000000000002567 80.0
HFD2_k127_567079_0 Fatty acid hydroxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 359.0
HFD2_k127_567079_1 enoyl-CoA hydratase K13766,K13779 - 4.2.1.18,4.2.1.57 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003497 348.0
HFD2_k127_567079_2 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006563 254.0
HFD2_k127_567079_3 Putative FMN-binding domain K07734 - - 0.000000000000000000000000000000000000000000000000000001365 198.0
HFD2_k127_567079_4 Protein of unknown function (DUF3667) - - - 0.000000000000000000000000000000000000000000000000000009775 205.0
HFD2_k127_567079_5 Protein of unknown function (DUF1489) - - - 0.000000000000000000000000000000000000000001375 160.0
HFD2_k127_567079_6 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K07001 - - 0.000000000000000000000000000225 119.0
HFD2_k127_567079_7 TIR domain - - - 0.000000001885 69.0
HFD2_k127_5690076_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 8.365e-220 689.0
HFD2_k127_5690076_1 Amino acid permease K20265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 388.0
HFD2_k127_5690076_2 COG2518 Protein-L-isoaspartate carboxylmethyltransferase K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000001649 190.0
HFD2_k127_5690076_3 PFAM Extensin family protein - - - 0.000000000000000000000000000000000000000000000004868 178.0
HFD2_k127_5690076_4 protein conserved in bacteria K09991 - - 0.000000000000000000002875 100.0
HFD2_k127_5728027_0 Belongs to the cytochrome P450 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 581.0
HFD2_k127_5728027_1 SPFH domain / Band 7 family - - - 0.00000000000000000000000000000000000000000000000000000000000000005409 229.0
HFD2_k127_5728027_2 Major facilitator superfamily MFS_1 K08178 - - 0.00000000000000000000000000000000000000000000000001389 191.0
HFD2_k127_5728027_3 Histidine kinase - - - 0.00000000003116 76.0
HFD2_k127_5737021_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0 1017.0
HFD2_k127_5737021_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071496 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 316.0
HFD2_k127_5737021_2 PFAM Glyoxalase bleomycin resistance protein dioxygenase K07032 - - 0.0000000000000000000000000000000000000000000003446 170.0
HFD2_k127_5771291_0 COG0768 Cell division protein FtsI penicillin-binding protein 2 K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004907 477.0
HFD2_k127_5771291_1 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 449.0
HFD2_k127_5771291_2 COG0767 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006534 366.0
HFD2_k127_5771291_3 Belongs to the SEDS family K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004442 359.0
HFD2_k127_5771291_4 ABC transporter, ATP-binding protein K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003559 309.0
HFD2_k127_5771291_5 Major facilitator superfamily K05820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008697 278.0
HFD2_k127_5771291_6 PFAM Mammalian cell entry related domain protein K02067 - - 0.000000000000000000000000000000000000000000000000003933 192.0
HFD2_k127_5771291_7 transport system, auxiliary component K18480 - - 0.00000000004609 71.0
HFD2_k127_578903_0 AsmA-like C-terminal region K07289 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 320.0
HFD2_k127_578903_1 Inner membrane protein CreD K06143 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 302.0
HFD2_k127_578903_2 Lactoylglutathione lyase and related lyases - - - 0.0000000000000000000000000000000000000000000000000002067 186.0
HFD2_k127_578903_3 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000002205 106.0
HFD2_k127_5800242_0 associated with various cellular activities K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 451.0
HFD2_k127_5800242_1 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 401.0
HFD2_k127_5800242_2 - - - - 0.000000000000000000000000000000000000000000000623 180.0
HFD2_k127_5800242_3 membrane - - - 0.000000001653 64.0
HFD2_k127_5801051_0 Hydrolase, TatD family K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000003588 235.0
HFD2_k127_5801051_1 DNA polymerase III K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000372 237.0
HFD2_k127_5801051_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000005751 153.0
HFD2_k127_5802714_0 Uncharacterised protein conserved in bacteria (DUF2336) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009133 315.0
HFD2_k127_5802714_1 Histidine kinase - - - 0.00003188 47.0
HFD2_k127_5850588_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 7.126e-201 640.0
HFD2_k127_5879752_0 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01966 - 2.1.3.15,6.4.1.3 1.891e-220 694.0
HFD2_k127_5879752_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 538.0
HFD2_k127_5879752_10 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000007691 126.0
HFD2_k127_5879752_12 transcriptional regulator K22108 - - 0.00000001376 65.0
HFD2_k127_5879752_14 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0003054 47.0
HFD2_k127_5879752_2 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000006491 262.0
HFD2_k127_5879752_3 Histidine kinase K03320 - - 0.000000000000000000000000000000000000000000000000000000000001781 227.0
HFD2_k127_5879752_4 PFAM acyltransferase 3 - - - 0.00000000000000000000000000000000000000000000000000000000001067 221.0
HFD2_k127_5879752_5 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000000000000000000000003167 215.0
HFD2_k127_5879752_6 membrane K07148 - - 0.0000000000000000000000000000000000000000000000000000000002728 219.0
HFD2_k127_5879752_7 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000000000001252 196.0
HFD2_k127_5879752_8 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06137 GO:0005575,GO:0005576 1.3.3.11 0.00000000000000000000000000000000000000000000000000006631 195.0
HFD2_k127_5879752_9 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.000000000000000000000000000000000000000000000000001742 184.0
HFD2_k127_5880703_0 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000155 269.0
HFD2_k127_5880703_1 Pilus assembly protein K02282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004653 275.0
HFD2_k127_5880703_2 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000007202 206.0
HFD2_k127_5880703_3 Protein of unknown function (DUF541) K09807 - - 0.0000000000000000000000000000000000000000000000000001104 194.0
HFD2_k127_5880703_4 - - - - 0.000000000000001267 79.0
HFD2_k127_5880703_5 - - - - 0.0000004986 53.0
HFD2_k127_5880703_6 - - - - 0.0000007958 57.0
HFD2_k127_5930154_0 COG1960 Acyl-CoA dehydrogenases K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 534.0
HFD2_k127_5930154_1 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 353.0
HFD2_k127_5930154_2 - - - - 0.00000000000000000000000424 112.0
HFD2_k127_5930154_3 Family of unknown function (DUF5367) - - - 0.0000000000001424 76.0
HFD2_k127_5930154_4 - - - - 0.0000000000671 73.0
HFD2_k127_5930154_5 excinuclease ABC activity K02342,K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 2.7.7.7 0.000003514 54.0
HFD2_k127_5932408_0 Sulfatase - - - 1.098e-219 688.0
HFD2_k127_5932408_1 Aspartyl/Asparaginyl beta-hydroxylase - - - 0.000000001467 65.0
HFD2_k127_5954337_0 PFAM Pyridoxal-dependent decarboxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 545.0
HFD2_k127_5954337_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 535.0
HFD2_k127_5954337_2 GTP cyclohydrolase K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007685 301.0
HFD2_k127_5957468_0 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 539.0
HFD2_k127_5957468_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007065 359.0
HFD2_k127_5957468_2 Histidine ammonia-lyase K01745 - 4.3.1.3 0.000000000000000004404 90.0
HFD2_k127_5957474_0 Iron-sulfur cluster assembly protein K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 339.0
HFD2_k127_5957474_1 major facilitator superfamily K08178 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 331.0
HFD2_k127_5957474_2 - - - - 0.0000005488 59.0
HFD2_k127_5964741_0 Acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000006245 239.0
HFD2_k127_5964741_1 DUF218 domain - - - 0.000000000000000000000000000000000000000000587 166.0
HFD2_k127_5964741_2 Uncharacterized protein conserved in bacteria (DUF2125) - - - 0.00000004229 63.0
HFD2_k127_5964741_3 Cell division protein K09811 - - 0.0009448 50.0
HFD2_k127_5986220_0 mitochondrial translation K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003871 398.0
HFD2_k127_5986220_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000544 353.0
HFD2_k127_5986220_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 344.0
HFD2_k127_5986220_3 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 338.0
HFD2_k127_5986220_4 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002561 313.0
HFD2_k127_5986220_5 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005776 247.0
HFD2_k127_5986220_6 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000001744 175.0
HFD2_k127_5989027_0 Glycine dehydrogenase (aminomethyl-transferring) K00281,K00283 - 1.4.4.2 2.209e-231 726.0
HFD2_k127_5989027_1 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 324.0
HFD2_k127_5989027_10 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000004289 107.0
HFD2_k127_5989027_2 Arginase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 329.0
HFD2_k127_5989027_3 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004578 289.0
HFD2_k127_5989027_4 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01485,K01487,K11991 - 3.5.4.1,3.5.4.3,3.5.4.33 0.000000000000000000000000000000000000000000000000000000000287 206.0
HFD2_k127_5989027_5 PFAM MaoC domain protein dehydratase K17865 GO:0003674,GO:0003824,GO:0003859,GO:0006081,GO:0006082,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044281,GO:0046487,GO:0071704 4.2.1.55 0.000000000000000000000000000000000000000000000000000007899 194.0
HFD2_k127_5989027_6 PFAM Integral membrane protein TerC - - - 0.000000000000000000000000000000000000000000000000004222 190.0
HFD2_k127_5989027_7 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000002045 166.0
HFD2_k127_5989027_8 Integral membrane protein TerC family - - - 0.0000000000000000000000000000000000000000002008 167.0
HFD2_k127_5989027_9 PFAM response regulator receiver K03413 - - 0.0000000000000000000000000000000000000001907 154.0
HFD2_k127_6001376_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 365.0
HFD2_k127_6001376_1 Phosphoenolpyruvate phosphomutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005148 272.0
HFD2_k127_6054442_0 COG2826 Transposase and inactivated derivatives, IS30 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 523.0
HFD2_k127_6054442_1 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006952 433.0
HFD2_k127_6054442_2 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009273 281.0
HFD2_k127_607731_0 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.000000000000000000000000000000000000000000000000000000000000012 221.0
HFD2_k127_607731_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000002625 208.0
HFD2_k127_607731_2 histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000038 108.0
HFD2_k127_6080195_0 L-gulonolactone oxidase-like K00103,K00225 - 1.1.3.8,1.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004347 552.0
HFD2_k127_6080195_1 Putative serine dehydratase domain - - - 0.00000000000000000000000000000000000001378 147.0
HFD2_k127_6080195_3 sequence-specific DNA binding K07726,K13655 - - 0.00000000001183 70.0
HFD2_k127_608059_0 COG0513 Superfamily II DNA and RNA helicases K17675 - 3.6.4.13 2.993e-250 799.0
HFD2_k127_608059_1 S4 RNA-binding domain K04762 - - 0.0000000000000000001559 94.0
HFD2_k127_6112714_0 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634,K08086,K20276 - - 0.0000000000000000000000000000003556 140.0
HFD2_k127_6144358_0 PFAM Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009712 391.0
HFD2_k127_6144358_1 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 347.0
HFD2_k127_6144358_2 thiolester hydrolase activity K17362 - - 0.0000000000000000000000000000000000000000000001248 173.0
HFD2_k127_6144358_3 Belongs to the ompA family - - - 0.0000000000000000000000000000000006554 136.0
HFD2_k127_6144358_4 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 0.0000000000000000000000000009203 113.0
HFD2_k127_6144358_6 - - - - 0.0003164 47.0
HFD2_k127_615045_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 7.343e-307 964.0
HFD2_k127_615045_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 1.23e-286 907.0
HFD2_k127_615045_10 Universal stress protein family - - - 0.0000000000000000001802 94.0
HFD2_k127_615045_2 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 617.0
HFD2_k127_615045_3 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008076 483.0
HFD2_k127_615045_4 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 331.0
HFD2_k127_615045_5 malic enzyme K00029 - 1.1.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 321.0
HFD2_k127_615045_6 COG0694 Thioredoxin-like proteins and domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001002 250.0
HFD2_k127_615045_7 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000000000000000000000000000001072 235.0
HFD2_k127_615045_8 PFAM peptidase M22 glycoprotease K14742 - - 0.000000000000000000000000000000000000008293 156.0
HFD2_k127_615045_9 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.00000000000000000000000000025 119.0
HFD2_k127_6212925_0 ATP-dependent DNA helicase RecG K03655 GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 1.386e-234 747.0
HFD2_k127_6212925_1 Cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 471.0
HFD2_k127_6212925_2 glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004783 366.0
HFD2_k127_6212925_3 Sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000002177 216.0
HFD2_k127_6212925_4 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.000000000000000000000001477 107.0
HFD2_k127_6212925_5 Flavinator of succinate dehydrogenase K09159 - - 0.000000000000000001073 91.0
HFD2_k127_6255826_0 MaoC like domain K14449 - 4.2.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 482.0
HFD2_k127_6255826_1 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 431.0
HFD2_k127_6255826_2 Belongs to the HpcH HpaI aldolase family K01644,K14451 - 3.1.2.30,4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 352.0
HFD2_k127_6255826_3 RarD protein K05786 - - 0.00000000000000000000000000000000000000000000000000000000192 216.0
HFD2_k127_6255826_4 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000422 194.0
HFD2_k127_6255826_5 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases K07313 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000002616 200.0
HFD2_k127_6255826_6 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000001299 186.0
HFD2_k127_6255826_7 Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP K00868 - 2.7.1.35 0.00000000000000000000000000000000000000000000004425 183.0
HFD2_k127_6255826_8 Glycosyltransferase family 87 - - - 0.00000000000000000000000000000000003518 149.0
HFD2_k127_6255826_9 - - - - 0.00000004199 57.0
HFD2_k127_6264594_0 AAA ATPase central domain protein K07478 - - 1.141e-201 636.0
HFD2_k127_6264594_1 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000000000000001801 135.0
HFD2_k127_6264594_2 Protein of unknown function (DUF992) - - - 0.00000000000000000000000000000000141 134.0
HFD2_k127_6264594_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000006558 49.0
HFD2_k127_6264594_4 - - - - 0.0001777 46.0
HFD2_k127_6266320_0 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004407 570.0
HFD2_k127_6266320_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 542.0
HFD2_k127_6266320_2 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 443.0
HFD2_k127_6266320_3 ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 356.0
HFD2_k127_6266320_4 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000003095 145.0
HFD2_k127_6266320_5 protein conserved in bacteria K09774 - - 0.00000000000000000000000000000001295 134.0
HFD2_k127_6266320_6 protein conserved in bacteria K11719 - - 0.000000000000000000000000005934 119.0
HFD2_k127_6266320_7 - - - - 0.0000000000001412 80.0
HFD2_k127_6271876_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 471.0
HFD2_k127_6271876_1 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000306 179.0
HFD2_k127_6271876_2 protein conserved in bacteria K09800 - - 0.000001029 52.0
HFD2_k127_631608_0 With MotB forms the ion channels that couple flagellar rotation to proton sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine K02556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 422.0
HFD2_k127_631608_1 Not a type III effector K08305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007958 341.0
HFD2_k127_631608_2 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001847 288.0
HFD2_k127_631608_3 Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 K15461 - 2.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000142 253.0
HFD2_k127_631608_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000001379 149.0
HFD2_k127_631608_5 Uncharacterized protein conserved in bacteria (DUF2312) - - - 0.00000000000000000000001015 103.0
HFD2_k127_631608_6 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000001046 77.0
HFD2_k127_631608_7 nitric oxide dioxygenase activity - - - 0.0000000007142 65.0
HFD2_k127_6405110_0 HAMP domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009448 371.0
HFD2_k127_6405110_1 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000001417 158.0
HFD2_k127_6405110_2 - - - - 0.00000000000000000000000000001575 120.0
HFD2_k127_644614_0 Threonine aldolase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 336.0
HFD2_k127_644614_1 Glycosyl transferase family group 2 - - - 0.00000000000000000000000000000000000000000000000000000000000001073 224.0
HFD2_k127_644614_2 sh3 domain protein - - - 0.0000000000000000000000000000000000000000000009255 177.0
HFD2_k127_6490109_0 Ferrous iron transport protein B K04759 - - 2.855e-211 674.0
HFD2_k127_6490109_1 AMP-binding enzyme C-terminal domain K08295 - 6.2.1.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002726 595.0
HFD2_k127_6490109_10 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000006806 102.0
HFD2_k127_6490109_11 FeoA K04758 - - 0.0000000000002958 74.0
HFD2_k127_6490109_12 sequence-specific DNA binding K16328 - 2.7.1.83 0.0000007346 55.0
HFD2_k127_6490109_2 Beta-Casp domain K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007474 570.0
HFD2_k127_6490109_3 Enoyl-CoA hydratase isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 412.0
HFD2_k127_6490109_4 alpha/beta hydrolase fold K01432 - 3.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 320.0
HFD2_k127_6490109_5 PFAM N-formylglutamate amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007996 270.0
HFD2_k127_6490109_6 PKHD-type hydroxylase K07336 - - 0.0000000000000000000000000000000000000000000000000000000000000004321 226.0
HFD2_k127_6490109_7 endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000000000000000001351 186.0
HFD2_k127_6490109_8 response regulator K13589 - - 0.000000000000000000000000000000000000000002973 173.0
HFD2_k127_6490109_9 Thioesterase superfamily K01075 - 3.1.2.23 0.00000000000000000000000000000004752 130.0
HFD2_k127_6517917_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 5.993e-243 759.0
HFD2_k127_6517917_1 NAD(P)H-binding - - - 0.0000000000000000000000000000001503 126.0
HFD2_k127_6520631_0 secretion system protein K02283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006118 407.0
HFD2_k127_6520631_1 Pilus assembly protein K02282 - - 0.000000000000000000000000000000004289 143.0
HFD2_k127_6520631_2 TadE-like protein - - - 0.0000000000000000000007793 97.0
HFD2_k127_6522105_0 B12 binding domain K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.0 1193.0
HFD2_k127_6522105_1 PFAM peptidase M16 domain protein K07263 - - 8.915e-278 888.0
HFD2_k127_6522105_2 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 415.0
HFD2_k127_6522105_3 Homocysteine S-methyltransferase K00544,K00548 - 2.1.1.13,2.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004387 407.0
HFD2_k127_6522105_4 Methylenetetrahydrofolate reductase K00297 GO:0003674,GO:0003824,GO:0004489,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009408 366.0
HFD2_k127_6522105_5 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005832 308.0
HFD2_k127_6522105_6 COG0500 SAM-dependent methyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001391 246.0
HFD2_k127_6522105_7 regulatory protein, arsR - - - 0.0000000000000000000000002457 106.0
HFD2_k127_6522105_8 Domain of unknown function (DUF4908) - - - 0.000000000000005844 85.0
HFD2_k127_6548479_0 TIGRFAM diguanylate cyclase K02488 GO:0003674,GO:0005488,GO:0005515,GO:0042802 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 509.0
HFD2_k127_6548479_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 452.0
HFD2_k127_6548479_2 Methionine aminopeptidase K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 403.0
HFD2_k127_6548479_3 PFAM ROK family K00847 - 2.7.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 338.0
HFD2_k127_6548479_4 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 297.0
HFD2_k127_6548479_5 cheY-homologous receiver domain K11443 - - 0.00000000000000000000000000000000000000000000000000004319 189.0
HFD2_k127_6548479_6 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000000000000000000000000000000001982 162.0
HFD2_k127_6548479_7 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000008685 137.0
HFD2_k127_6555600_0 GMC oxidoreductase - - - 1.349e-282 882.0
HFD2_k127_6555600_1 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 593.0
HFD2_k127_6555600_10 PFAM conserved - - - 0.0000000000000000000000000000000000000003738 158.0
HFD2_k127_6555600_11 COG0778 Nitroreductase - - - 0.00000000000000000000000001431 112.0
HFD2_k127_6555600_2 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008134 570.0
HFD2_k127_6555600_3 COG0330 Membrane protease subunits, stomatin prohibitin homologs - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 384.0
HFD2_k127_6555600_4 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 323.0
HFD2_k127_6555600_5 HMGL-like K01640,K18314 - 4.1.3.4,4.1.3.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 318.0
HFD2_k127_6555600_6 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000008377 259.0
HFD2_k127_6555600_7 UPF0126 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000008506 237.0
HFD2_k127_6555600_8 Redoxin domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000002672 218.0
HFD2_k127_6555600_9 Belongs to the UPF0301 (AlgH) family K07735 - - 0.000000000000000000000000000000000000000000000000000001821 196.0
HFD2_k127_6585811_0 Domain of unknown function (DUF4332) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 411.0
HFD2_k127_6585811_1 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000001885 245.0
HFD2_k127_6585811_2 Protein of unknown function (DUF1524) - - - 0.000000000000000000000000000000000000000000000000000000000000000000002271 256.0
HFD2_k127_6585811_3 Protein of unknown function (DUF3108) - - - 0.0000000000000000002683 98.0
HFD2_k127_6585811_4 COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III - - - 0.00000000000000001493 94.0
HFD2_k127_6628658_0 Putative esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 325.0
HFD2_k127_6628658_1 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 287.0
HFD2_k127_6628658_2 acetylornithine aminotransferase K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000004412 243.0
HFD2_k127_6628658_3 GcrA cell cycle regulator K13583 - - 0.00000000000000000000000000000000000000000000000001804 187.0
HFD2_k127_6628658_4 - - - - 0.00000000000000000000000000000000000000000006689 164.0
HFD2_k127_6628658_5 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000009044 123.0
HFD2_k127_6628658_6 Acetyltransferase (GNAT) domain - - - 0.000000005707 57.0
HFD2_k127_6636234_0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 487.0
HFD2_k127_6636234_1 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 0.000000000000000000000000000000000000000004229 170.0
HFD2_k127_6636234_2 - - - - 0.0000000000000000000000007204 111.0
HFD2_k127_6636234_3 - - - - 0.00000000000000000006941 95.0
HFD2_k127_6685403_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009577 349.0
HFD2_k127_6685403_1 HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 314.0
HFD2_k127_6685403_2 Phospholipase/Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001174 274.0
HFD2_k127_6714212_0 COG0277 FAD FMN-containing dehydrogenases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 472.0
HFD2_k127_6714212_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001025 280.0
HFD2_k127_6729785_0 COG0842 ABC-type multidrug transport system, permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004482 454.0
HFD2_k127_6729785_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008235 427.0
HFD2_k127_6729785_2 Inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000001001 114.0
HFD2_k127_6769272_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 526.0
HFD2_k127_6769272_1 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000003601 198.0
HFD2_k127_6769272_2 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000003841 134.0
HFD2_k127_6776828_0 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 290.0
HFD2_k127_6776828_1 TIGRFAM periplasmic protein thiol disulphide oxidoreductase DsbE K02199 - - 0.0000000000000000000000000000000000000001709 156.0
HFD2_k127_6776828_2 probably involved in intracellular septation K06190 - - 0.00000000000000000000000000000000000002884 151.0
HFD2_k127_6776828_3 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000000000000000000000000009367 150.0
HFD2_k127_6776828_4 COG1846 Transcriptional regulators - - - 0.000000000000000000000000000494 121.0
HFD2_k127_6776828_5 ATPases associated with a variety of cellular activities K02193 - 3.6.3.41 0.000000000000000000001102 96.0
HFD2_k127_6805360_0 Diguanylate cyclase - - - 1.159e-229 735.0
HFD2_k127_6805360_1 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 394.0
HFD2_k127_6805360_10 Domain of unknown function (DUF4282) - - - 0.00000000003169 69.0
HFD2_k127_6805360_11 nuclear chromosome segregation - - - 0.00009623 55.0
HFD2_k127_6805360_12 - - - - 0.0005671 49.0
HFD2_k127_6805360_2 Autotransporter beta- domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 391.0
HFD2_k127_6805360_3 SMART PAS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 369.0
HFD2_k127_6805360_4 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004357 302.0
HFD2_k127_6805360_5 NnrU protein - - - 0.0000000000000000000000000000000000000000000005575 175.0
HFD2_k127_6805360_6 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000001972 138.0
HFD2_k127_6805360_7 thioesterase K07107 - - 0.00000000000000000000000000000000005256 138.0
HFD2_k127_6805360_8 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000002113 83.0
HFD2_k127_6805360_9 Histidine kinase K07647 - 2.7.13.3 0.0000000000003451 73.0
HFD2_k127_6867034_0 glyoxalase III activity K02005 - - 0.000000000000000000000000000000000000000000000000000000153 199.0
HFD2_k127_6867034_1 DNA alkylation repair - - - 0.000000000000000000000000000000000000000000000000000001448 197.0
HFD2_k127_6867034_2 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.0000000000000000000000000000000000000000000000000001494 189.0
HFD2_k127_6867034_3 3-demethylubiquinone-9 3-methyltransferase - - - 0.00000000000000000000000000000000000000000000001536 174.0
HFD2_k127_6867034_4 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000007006 159.0
HFD2_k127_6867034_5 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000000001896 158.0
HFD2_k127_6925213_0 Uncharacterized protein conserved in bacteria (DUF2332) K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 358.0
HFD2_k127_6925213_1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000001688 183.0
HFD2_k127_6925213_2 energy transducer activity K03832 - - 0.00000001822 64.0
HFD2_k127_694808_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 8.705e-197 623.0
HFD2_k127_694808_1 protein conserved in bacteria K09919 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009376 451.0
HFD2_k127_694808_2 Glycine zipper 2TM domain - - - 0.00008264 50.0
HFD2_k127_695689_0 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003996 534.0
HFD2_k127_695689_1 Dehydrogenase K00210,K00220,K04517 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0047794,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12,1.3.1.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 394.0
HFD2_k127_695689_2 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000045 389.0
HFD2_k127_695689_3 Conserved protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001719 239.0
HFD2_k127_695689_4 TIGRFAM methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000000000002365 178.0
HFD2_k127_695689_5 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000003132 166.0
HFD2_k127_695689_6 chorismate mutase - - - 0.0000000000000001849 89.0
HFD2_k127_6961216_0 L,D-transpeptidase catalytic domain K21470,K21572 - - 0.000000000000000000000000000000000000000000000000000000000000000006066 239.0
HFD2_k127_6961216_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000165 115.0
HFD2_k127_6961216_2 Putative peptidoglycan binding domain K21470 - - 0.000000000000000003273 92.0
HFD2_k127_7016663_0 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005369 513.0
HFD2_k127_7016663_1 Belongs to the N(4) N(6)-methyltransferase family K13581 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005495 424.0
HFD2_k127_7016663_2 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009553 416.0
HFD2_k127_7016663_3 glycosyl transferase family 39 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004059 351.0
HFD2_k127_7016663_4 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000001213 207.0
HFD2_k127_7016663_5 PFAM helix-turn-helix domain protein K07729 - - 0.000000000000000000000000003883 113.0
HFD2_k127_7016663_6 - - - - 0.00000000000000001184 87.0
HFD2_k127_7071782_0 Fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 437.0
HFD2_k127_7071782_1 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 370.0
HFD2_k127_7071782_10 Adenylate cyclase - - - 0.000000000000000008983 88.0
HFD2_k127_7071782_11 - - - - 0.000000001023 67.0
HFD2_k127_7071782_2 Stage II sporulation protein M - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 346.0
HFD2_k127_7071782_3 RDD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 309.0
HFD2_k127_7071782_4 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001265 289.0
HFD2_k127_7071782_5 Poly3-Hydroxybutyrate Depolymerase K03932 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002153 263.0
HFD2_k127_7071782_6 COG1309 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003501 244.0
HFD2_k127_7071782_7 - - - - 0.000000000000000000000000000000000000000001428 169.0
HFD2_k127_7071782_8 - - - - 0.000000000000000000000000000000004263 140.0
HFD2_k127_7071782_9 GCN5-related N-acetyl-transferase K06975 - - 0.00000000000000000000000000003904 123.0
HFD2_k127_7085078_0 COG0744 Membrane carboxypeptidase (penicillin-binding protein) K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 546.0
HFD2_k127_7085078_1 COG0488 ATPase components of ABC transporters with duplicated ATPase domains K15738 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010528,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031323,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0070894,GO:0071944,GO:0080090,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 532.0
HFD2_k127_7085078_2 Terminase RNaseH-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 405.0
HFD2_k127_7100050_0 DEAD DEAH box helicase K03724 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007088 597.0
HFD2_k127_7100050_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001858 235.0
HFD2_k127_7100050_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000003246 110.0
HFD2_k127_7100050_3 - - - - 0.000000000000001396 85.0
HFD2_k127_7100050_4 Domain of unknown function (DUF1330) - - - 0.000000003682 67.0
HFD2_k127_7100050_5 Response regulator receiver - - - 0.000000004898 63.0
HFD2_k127_7120452_0 Transketolase, pyrimidine binding domain K00167 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 574.0
HFD2_k127_7120452_1 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal K00166 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008371 539.0
HFD2_k127_7120452_2 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K09699 - 2.3.1.168 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005423 314.0
HFD2_k127_7126645_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003172 267.0
HFD2_k127_7139374_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 1.658e-240 751.0
HFD2_k127_7139374_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004481 432.0
HFD2_k127_7139374_10 Protein of unknown function (DUF2459) - - - 0.0000000000000000000000000000000308 135.0
HFD2_k127_7139374_11 TIR domain - - - 0.0000000000000000000000000000003161 134.0
HFD2_k127_7139374_12 TIR domain - - - 0.000000000000000000000000000002541 133.0
HFD2_k127_7139374_13 Type II secretion system (T2SS), protein G - - - 0.000000000000000000000000003617 116.0
HFD2_k127_7139374_14 Protein of unknown function (DUF805) - - - 0.0000000000000000000006174 106.0
HFD2_k127_7139374_15 Uncharacterized protein conserved in bacteria (DUF2171) - - - 0.0000000000000000000007448 98.0
HFD2_k127_7139374_16 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000001116 96.0
HFD2_k127_7139374_17 - - - - 0.00000000000000001145 94.0
HFD2_k127_7139374_18 Ribbon-helix-helix domain - - - 0.00000000000000002059 84.0
HFD2_k127_7139374_2 SMP-30 Gluconolaconase K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003746 401.0
HFD2_k127_7139374_20 Domain of unknown function (DUF4169) - - - 0.00000000001941 66.0
HFD2_k127_7139374_3 Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity K06188 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003836 299.0
HFD2_k127_7139374_4 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009004 256.0
HFD2_k127_7139374_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000001464 224.0
HFD2_k127_7139374_6 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.0000000000000000000000000000000000000000000000000000009084 196.0
HFD2_k127_7139374_7 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000139 176.0
HFD2_k127_7139374_8 protein conserved in bacteria K09985 - - 0.0000000000000000000000000000000000000000000001547 173.0
HFD2_k127_7139374_9 endodeoxyribonuclease RusA - - - 0.000000000000000000000000000000000000000001662 159.0
HFD2_k127_7171803_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015627,GO:0015628,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:0098776,GO:1901265,GO:1901363,GO:1904680 - 0.0 1227.0
HFD2_k127_7171803_1 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 612.0
HFD2_k127_7171803_10 PFAM Flp Fap pilin component K02651 - - 0.0000001026 58.0
HFD2_k127_7171803_2 Acetylornithine deacetylase Succinyl-diaminopimelate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 527.0
HFD2_k127_7171803_3 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007829 474.0
HFD2_k127_7171803_4 Protein of unknown function (DUF1217) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003527 262.0
HFD2_k127_7171803_5 NUDIX domain K03574 GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.55 0.00000000000000000000000000000000000000000000008439 173.0
HFD2_k127_7171803_6 Peptidylprolyl isomerase K01802,K03769 - 5.2.1.8 0.0000000000000000000000000000000000003622 156.0
HFD2_k127_7171803_7 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000000000000000000000002263 114.0
HFD2_k127_7171803_8 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000009777 87.0
HFD2_k127_7171803_9 Glutathione S-transferase, C-terminal domain K00799 GO:0000302,GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0009636,GO:0010035,GO:0016740,GO:0016765,GO:0042221,GO:0042493,GO:0042542,GO:0044424,GO:0044464,GO:0046677,GO:0050896,GO:1901700 2.5.1.18 0.00000000001552 72.0
HFD2_k127_7204466_0 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 - 2.1.1.266 0.0000000000000000000000000000000000000000000000000000000000000000000000000009536 262.0
HFD2_k127_7204466_1 PFAM Chorismate mutase K04782 - 4.2.99.21 0.00000000000000000000000000000001153 131.0
HFD2_k127_7204466_2 Cold shock protein domain K03704 - - 0.000000000000000000000000129 116.0
HFD2_k127_7204466_3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 - 0.00000000000001811 75.0
HFD2_k127_7204466_4 glyoxalase III activity - - - 0.00000000002039 75.0
HFD2_k127_7204466_5 - - - - 0.00000000008321 72.0
HFD2_k127_7204466_6 GCN5-related N-acetyl-transferase K06975 - - 0.000158 45.0
HFD2_k127_722736_0 Histidine kinase K11357 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 0.0000000000000000000000000000000000000000000000000003736 202.0
HFD2_k127_722736_1 - - - - 0.0000000000001516 81.0
HFD2_k127_722736_2 - - - - 0.0009972 48.0
HFD2_k127_7229786_0 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009468 350.0
HFD2_k127_7229786_1 Belongs to the peptidase S1B family - - - 0.0000000000000000000000000000000000000000000001087 174.0
HFD2_k127_7229786_2 Type III flagellar switch regulator (C-ring) FliN C-term K02417 - - 0.00000000000000000000000000003174 118.0
HFD2_k127_7229786_3 Copper resistance protein D K07245,K14166 - - 0.00000000000000000000000465 108.0
HFD2_k127_7229786_4 Copper resistance protein K07156 - - 0.000000000000000003423 91.0
HFD2_k127_7229786_5 - - - - 0.000000000000002268 81.0
HFD2_k127_7229786_6 - - - - 0.0000000000001128 76.0
HFD2_k127_7318922_0 PFAM class II aldolase adducin family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004705 395.0
HFD2_k127_7318922_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 390.0
HFD2_k127_7318922_2 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 327.0
HFD2_k127_7318922_3 Cytochrome c K08738 - - 0.00000000000000000000000000000000000000001473 158.0
HFD2_k127_7318922_4 N-acetylmuramidase - - - 0.000000000000000000000000000000000000002011 160.0
HFD2_k127_7318922_5 Histidine kinase - - - 0.000000000000006149 79.0
HFD2_k127_7370030_0 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 317.0
HFD2_k127_7385447_0 Major Facilitator - - - 8.419e-207 657.0
HFD2_k127_7385447_1 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 581.0
HFD2_k127_7385447_10 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000008947 210.0
HFD2_k127_7385447_11 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000001008 181.0
HFD2_k127_7385447_12 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.0000000000000000000000000000000000000000000002801 186.0
HFD2_k127_7385447_13 Rod shape-determining protein MreC K03570 - - 0.00000000000000000000000000000000000000000008539 175.0
HFD2_k127_7385447_14 - - - - 0.00000000000000000000000000000000001116 145.0
HFD2_k127_7385447_15 electron transfer activity - - - 0.0000000000000000000000000000000002084 145.0
HFD2_k127_7385447_16 COG0322 Nuclease subunit of the excinuclease complex - - - 0.0000000000000000000000000000000002506 140.0
HFD2_k127_7385447_17 response to abiotic stimulus K01243,K06867 - 3.2.2.9 0.000000000000000000000000000005322 124.0
HFD2_k127_7385447_18 Protein of unknown function (DUF3140) - - - 0.000000000000000000000000000008137 125.0
HFD2_k127_7385447_19 - - - - 0.000000000000000004089 96.0
HFD2_k127_7385447_2 Glucose sorbosone dehydrogenases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 485.0
HFD2_k127_7385447_20 Belongs to the heme-copper respiratory oxidase family - - - 0.00000000000002363 78.0
HFD2_k127_7385447_21 shape-determining protein K03571 - - 0.0001725 52.0
HFD2_k127_7385447_3 Rod shape-determining protein MreB K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 460.0
HFD2_k127_7385447_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000465 404.0
HFD2_k127_7385447_5 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000934 400.0
HFD2_k127_7385447_6 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 354.0
HFD2_k127_7385447_7 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004235 340.0
HFD2_k127_7385447_8 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009805 314.0
HFD2_k127_7385447_9 Bacterial protein of unknown function (DUF924) - - - 0.000000000000000000000000000000000000000000000000000000000442 211.0
HFD2_k127_7395815_0 VWA domain containing CoxE-like protein K09989 - - 2.667e-210 662.0
HFD2_k127_7395815_1 AAA domain (dynein-related subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 484.0
HFD2_k127_7395815_2 Trypsin K08070 - 1.3.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004156 364.0
HFD2_k127_7395815_3 Has a post-transcriptional repressor function in flagellum biogenesis. Associates with the 5'-UTR of fljK K06601 - - 0.000000000000000000000000000000000000000000000000000000009631 201.0
HFD2_k127_7395815_4 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000003057 188.0
HFD2_k127_7395815_5 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.0000000000000000000000000000000001102 146.0
HFD2_k127_7395815_6 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0000000000000000000000000000002005 128.0
HFD2_k127_7395815_7 Flagellar protein FlaF K06602 - - 0.0000000000000000000003735 100.0
HFD2_k127_7395815_8 - - - - 0.000005661 52.0
HFD2_k127_7451818_0 PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 4.32e-209 673.0
HFD2_k127_7451818_1 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 606.0
HFD2_k127_7451818_2 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 562.0
HFD2_k127_7451818_3 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004101 536.0
HFD2_k127_7451818_4 Transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 295.0
HFD2_k127_7451818_5 Domain of unknown function (DUF1993) K09983 - - 0.0000000000000000000000000000000000000000003369 163.0
HFD2_k127_7451818_6 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.000000000000000000000000000000000001424 146.0
HFD2_k127_7451818_7 - - - - 0.0000000000000000696 82.0
HFD2_k127_7451818_8 - - - - 0.0000000000008139 75.0
HFD2_k127_7451818_9 Cell division protein ZapA K09888 - - 0.0001734 48.0
HFD2_k127_7465887_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 560.0
HFD2_k127_7482257_0 AAA domain, putative AbiEii toxin, Type IV TA system K06926 - - 0.00000000000000000000000000000000000000000000009306 175.0
HFD2_k127_7482257_1 AAA domain, putative AbiEii toxin, Type IV TA system K06926 - - 0.000000000000000000000000000000001069 134.0
HFD2_k127_7482257_2 Aspartyl protease - - - 0.0000000000000000000000000001963 125.0
HFD2_k127_7500560_0 acyl-CoA dehydrogenase K00248,K00249,K20035 - 1.3.8.1,1.3.8.7 5.655e-197 628.0
HFD2_k127_7500560_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 492.0
HFD2_k127_7500560_2 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 329.0
HFD2_k127_7500560_3 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001812 246.0
HFD2_k127_7500560_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000409 220.0
HFD2_k127_7500560_5 Belongs to the UPF0312 family - - - 0.00000000000000000000000000001166 126.0
HFD2_k127_7500560_6 Putative heavy-metal-binding - - - 0.00000000000000000000000000001643 120.0
HFD2_k127_7500560_7 - - - - 0.0000008387 59.0
HFD2_k127_7508389_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003105 459.0
HFD2_k127_7508389_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000002564 199.0
HFD2_k127_7508389_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000007618 188.0
HFD2_k127_7508389_3 E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate K00164 - 1.2.4.2 0.00000000000000005834 83.0
HFD2_k127_7508389_4 Protein of unknown function (DUF1211) - - - 0.0000000000000007663 79.0
HFD2_k127_7528480_0 Proton-conducting membrane transporter - - - 5.673e-276 863.0
HFD2_k127_7528480_1 transcriptional regulator - - - 0.00000000000000000000000000003526 117.0
HFD2_k127_7528480_2 NADH dehydrogenase - - - 0.0000315 50.0
HFD2_k127_7545421_0 Involved in the TonB-independent uptake of proteins K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 546.0
HFD2_k127_7545421_1 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000000000000000000002595 184.0
HFD2_k127_7545421_2 Biopolymer transport protein K03559,K03560 - - 0.0000000000000000000000000000000000000000000005226 171.0
HFD2_k127_7545421_3 COG0811 Biopolymer transport proteins K03562 - - 0.00000000000000000000000205 103.0
HFD2_k127_7545421_4 domain, Protein - - - 0.000000000000000001461 95.0
HFD2_k127_7546346_0 Belongs to the helicase family. UvrD subfamily K16898 - 3.6.4.12 8.216e-230 754.0
HFD2_k127_7546346_1 COG3893 Inactivated superfamily I helicase K16899 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 308.0
HFD2_k127_7546346_2 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000004564 218.0
HFD2_k127_7546346_3 Thioredoxin-like domain K03671 - - 0.0000000000000000000000000000000000000000000000004261 177.0
HFD2_k127_7547324_0 NAD FAD-binding protein K06954 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 517.0
HFD2_k127_7547324_1 Protein of unknown function (DUF1365) K09701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001958 259.0
HFD2_k127_7547324_2 Bacterial protein of unknown function (DUF853) K06915 - - 0.000001186 55.0
HFD2_k127_7580107_0 COG4553 Poly-beta-hydroxyalkanoate depolymerase K05973 - 3.1.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004803 570.0
HFD2_k127_7580107_1 Penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000515 528.0
HFD2_k127_7580107_2 Belongs to the BI1 family K06890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003605 282.0
HFD2_k127_7580107_3 Protein of unknown function DUF45 K07043 - - 0.0000000000000000000000000000000000000000000000000000000002307 218.0
HFD2_k127_7580107_4 Prokaryotic cytochrome b561 K12262 - - 0.00000000000000000000000000000000000005784 149.0
HFD2_k127_7580107_5 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000001646 140.0
HFD2_k127_7580107_6 Protein of unknown function (DUF2794) - - - 0.00000000000000000000000000001049 121.0
HFD2_k127_7580107_7 Phosphodiester glycosidase - - - 0.000000000622 63.0
HFD2_k127_7580107_8 ABC-type multidrug transport system, ATPase component K01990 - - 0.00000008619 54.0
HFD2_k127_7584648_0 Protein of unknown function (DUF817) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000298 477.0
HFD2_k127_7584648_1 GTP cyclohydrolase K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 315.0
HFD2_k127_7584648_2 FAD dependent oxidoreductase K00301 - 1.5.3.1 0.000000000000000008308 87.0
HFD2_k127_7591416_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 3.895e-194 617.0
HFD2_k127_7591416_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 556.0
HFD2_k127_7591416_10 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 329.0
HFD2_k127_7591416_11 COG0768 Cell division protein FtsI penicillin-binding protein 2 K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000008007 274.0
HFD2_k127_7591416_2 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 548.0
HFD2_k127_7591416_3 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003788 437.0
HFD2_k127_7591416_4 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01928,K01929,K15792 - 6.3.2.10,6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003422 428.0
HFD2_k127_7591416_5 amino acid peptide transporter K03305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 407.0
HFD2_k127_7591416_6 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007521 396.0
HFD2_k127_7591416_7 Belongs to the D-alanine--D-alanine ligase family K00075,K01921 - 1.3.1.98,6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005606 391.0
HFD2_k127_7591416_8 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 390.0
HFD2_k127_7591416_9 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000843 341.0
HFD2_k127_7594803_0 Beta propeller domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 508.0
HFD2_k127_7594803_1 COG1226 Kef-type K transport systems K10716 - - 0.000000000000000000000000000000000000000000000000000000000000003194 226.0
HFD2_k127_7594803_2 Protein of unknown function (DUF1134) - - - 0.00000000000000000000000000000000000000000000000000000000000002515 219.0
HFD2_k127_7607119_0 Metallo-beta-lactamase superfamily - - - 1.35e-262 822.0
HFD2_k127_7607119_1 major facilitator superfamily K03446 - - 1.351e-239 750.0
HFD2_k127_7607119_10 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000002802 214.0
HFD2_k127_7607119_11 AefR-like transcriptional repressor, C-terminal region - - - 0.00000000000000000000000000000000000000000000000000000003189 208.0
HFD2_k127_7607119_12 Oxidoreductase FAD-binding domain K00523,K02613 - 1.17.1.1 0.000000000000000000000000000000000000000000000000002774 184.0
HFD2_k127_7607119_13 - - - - 0.0000000000006883 76.0
HFD2_k127_7607119_14 DNA methylase - - - 0.00000000006576 63.0
HFD2_k127_7607119_15 - - - - 0.0003573 49.0
HFD2_k127_7607119_2 Glycosyl transferases group 1 - - - 2.031e-239 763.0
HFD2_k127_7607119_3 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002701 557.0
HFD2_k127_7607119_4 beta-1,4-mannooligosaccharide phosphorylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 504.0
HFD2_k127_7607119_5 Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons K01563 - 3.8.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003968 482.0
HFD2_k127_7607119_6 Sodium/hydrogen exchanger family K03316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008284 384.0
HFD2_k127_7607119_7 PFAM secretion protein HlyD family protein K03543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 305.0
HFD2_k127_7607119_8 2-hydroxychromene-2-carboxylate isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001825 253.0
HFD2_k127_7607119_9 Serine hydrolase K07002 - - 0.000000000000000000000000000000000000000000000000000000000000000008219 230.0
HFD2_k127_7608564_0 flagellar basal-body rod protein FlgG K02392 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003959 345.0
HFD2_k127_7608564_1 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003671 256.0
HFD2_k127_7608564_2 bacterial-type flagellum organization K02279,K02386 - - 0.000000000001275 78.0
HFD2_k127_7624165_0 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007095 370.0
HFD2_k127_7624165_1 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 348.0
HFD2_k127_7624165_2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007168 287.0
HFD2_k127_7624165_3 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000003556 249.0
HFD2_k127_7624165_4 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000001047 214.0
HFD2_k127_7624165_5 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000000000000000000000009142 186.0
HFD2_k127_7624165_6 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000006592 119.0
HFD2_k127_7624165_7 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951,K01139 - 2.7.6.5,3.1.7.2 0.00000000000000000000000008817 109.0
HFD2_k127_7624165_8 - - - - 0.0000000000000000000006898 106.0
HFD2_k127_7638698_0 oxidase subunit I K00425 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006922 581.0
HFD2_k127_7638698_1 C-terminus of AA_permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005612 491.0
HFD2_k127_7638698_10 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005171 269.0
HFD2_k127_7638698_11 COG1309 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000001183 210.0
HFD2_k127_7638698_12 Domain of Unknown Function (DUF350) K08989 - - 0.000000000000000000000000000000000000001862 151.0
HFD2_k127_7638698_13 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000000000001846 148.0
HFD2_k127_7638698_14 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.000000000000000000000000004393 115.0
HFD2_k127_7638698_15 Rieske [2Fe-2S] domain - - - 0.00000000000000000000001724 106.0
HFD2_k127_7638698_16 Belongs to the UPF0235 family K09131 - - 0.000000000000000000006835 94.0
HFD2_k127_7638698_18 Protein of unknown function (DUF2167) - - - 0.0000000000006437 79.0
HFD2_k127_7638698_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360,GO:1901564 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 415.0
HFD2_k127_7638698_3 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 405.0
HFD2_k127_7638698_4 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 GO:0003674,GO:0003824,GO:0006072,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 395.0
HFD2_k127_7638698_5 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007218 396.0
HFD2_k127_7638698_6 short-chain dehydrogenase K05296 - 1.1.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007671 354.0
HFD2_k127_7638698_7 Belongs to the short-chain dehydrogenases reductases (SDR) family K00019 - 1.1.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005202 335.0
HFD2_k127_7638698_8 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 312.0
HFD2_k127_7638698_9 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000366 299.0
HFD2_k127_7653306_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 7.173e-259 813.0
HFD2_k127_7653306_1 PFAM lipopolysaccharide biosynthesis protein K16554 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 469.0
HFD2_k127_7653306_10 3'(2'),5'-bisphosphate nucleotidase K01082 - 3.1.3.7 0.000000000000000000000000000000000000000000000000000000185 202.0
HFD2_k127_7653306_11 response regulator - - - 0.0000000000000000000000000000000000002167 145.0
HFD2_k127_7653306_12 Heat shock 70 kDa protein - - - 0.000000000000000000000002512 118.0
HFD2_k127_7653306_13 Bacterial sugar transferase K00996,K16566 - 2.7.8.6 0.000000000000000000007478 102.0
HFD2_k127_7653306_14 PFAM polysaccharide export protein K01991 - - 0.00000000000000000005468 90.0
HFD2_k127_7653306_15 PFAM lipopolysaccharide biosynthesis protein K16554 - - 0.0000000000000000001676 101.0
HFD2_k127_7653306_16 protein conserved in bacteria K09978 - - 0.000000000000000002988 90.0
HFD2_k127_7653306_17 YnbE-like lipoprotein - - - 0.00000000000003623 74.0
HFD2_k127_7653306_18 - - - - 0.0000000000593 68.0
HFD2_k127_7653306_19 COG0591 Na proline symporter - - - 0.0000002421 59.0
HFD2_k127_7653306_2 transferase activity, transferring glycosyl groups K16558 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 376.0
HFD2_k127_7653306_20 - - - - 0.000000653 53.0
HFD2_k127_7653306_21 regulator - - - 0.0007856 46.0
HFD2_k127_7653306_3 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009862 337.0
HFD2_k127_7653306_4 Dicarboxylate transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 329.0
HFD2_k127_7653306_5 Glycosyl transferase family group 2 K16557 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 297.0
HFD2_k127_7653306_6 Putative beta-barrel porin 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006861 258.0
HFD2_k127_7653306_7 Exopolysaccharide production protein K00996,K16566 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.8.6 0.00000000000000000000000000000000000000000000000000000000000000166 229.0
HFD2_k127_7653306_8 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000005504 235.0
HFD2_k127_7653306_9 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000006734 201.0
HFD2_k127_7659229_0 Cysteine synthase A K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 473.0
HFD2_k127_7659229_1 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 316.0
HFD2_k127_7659229_2 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.0000000000000000000000000000000000000000000000000000000000000000001252 232.0
HFD2_k127_7704396_0 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 5.188e-209 661.0
HFD2_k127_7704396_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 450.0
HFD2_k127_7704396_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 328.0
HFD2_k127_7704396_3 Prolyl 4-hydroxylase alpha subunit homologues. - - - 0.0000000000000000000000000000000000000000000000000000000000008481 217.0
HFD2_k127_7704396_4 Urate oxidase N-terminal - - - 0.00000000000000000000000000000000000000000000000000000003046 207.0
HFD2_k127_7704396_5 Lysin motif K06194 - - 0.000000000000000000000000000000000000000000255 171.0
HFD2_k127_7704396_6 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000007513 151.0
HFD2_k127_7704396_7 Preprotein translocase subunit (YajC) K03210 - - 0.0000000000000000000000004623 108.0
HFD2_k127_7704396_8 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000008285 55.0
HFD2_k127_7707624_0 COG2853 Surface lipoprotein K04754 - - 0.00000000000000000000000000000000000000000000000000000000000003378 225.0
HFD2_k127_7707624_1 Dihydroorotate dehydrogenase (quinone) K00254 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044205,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.3.5.2 0.0000000000000000000000000000000000000000000000000000000009579 205.0
HFD2_k127_7707624_2 transcriptional - - - 0.00000000000000000000000000000000000000000000006142 175.0
HFD2_k127_7707624_3 MlaC protein K07323 - - 0.000000000000000000000000000000008353 136.0
HFD2_k127_7708210_0 Belongs to the MIP aquaporin (TC 1.A.8) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003228 258.0
HFD2_k127_7708210_1 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000001428 249.0
HFD2_k127_7708210_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000009849 203.0
HFD2_k127_7708210_3 - - - - 0.00000000000000000000000000000000000000000000000000002866 189.0
HFD2_k127_7708210_4 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000000000000000000000000001642 143.0
HFD2_k127_7708210_5 - - - - 0.000007298 50.0
HFD2_k127_77234_0 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004869 555.0
HFD2_k127_77234_1 Peptidase S46 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 561.0
HFD2_k127_77234_10 EF-hand, calcium binding motif - - - 0.000000000000000005298 92.0
HFD2_k127_77234_11 COG1668 ABC-type Na efflux pump, permease component K01992 - - 0.0000001214 55.0
HFD2_k127_77234_2 alpha/beta hydrolase fold K01066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003894 384.0
HFD2_k127_77234_3 Efflux ABC transporter permease protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005032 374.0
HFD2_k127_77234_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 312.0
HFD2_k127_77234_5 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005642 290.0
HFD2_k127_77234_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000566 269.0
HFD2_k127_77234_7 EVE domain - - - 0.00000000000000000000000000000000000000000000000000000000003287 209.0
HFD2_k127_77234_8 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.0000000000000000000000000000000000000000000000000000009573 209.0
HFD2_k127_77234_9 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000007894 177.0
HFD2_k127_7724910_0 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008209 285.0
HFD2_k127_7724910_1 Belongs to the UPF0312 family K12262 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001864 245.0
HFD2_k127_7724910_2 Glycosyl transferase family 21 - - - 0.0000000000000000000000000000000000000000000000000003921 191.0
HFD2_k127_7724910_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000002504 156.0
HFD2_k127_7736639_0 Peptidase family M3 K01284 - 3.4.15.5 3.154e-260 822.0
HFD2_k127_7736639_1 phospholipase C K01114 - 3.1.4.3 6.726e-236 748.0
HFD2_k127_7736639_2 COG2015 Alkyl sulfatase and related hydrolases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004336 447.0
HFD2_k127_7736639_3 - - - - 0.00000000000000000001284 104.0
HFD2_k127_7736639_4 Histidine kinase - - - 0.0000001815 53.0
HFD2_k127_7736639_5 - - - - 0.00005483 53.0
HFD2_k127_7785787_0 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007136 306.0
HFD2_k127_7785787_1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K09699 - 2.3.1.168 0.000000000000000000000000000000000000000000000000000000000000002419 220.0
HFD2_k127_7785787_2 DoxX - - - 0.0000000000000000000000000000000000000000006215 169.0
HFD2_k127_7785787_3 TIR domain - - - 0.00000000000000000000000000000366 131.0
HFD2_k127_7807490_0 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 GO:0003674,GO:0003824,GO:0003849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009507,GO:0009536,GO:0009611,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0050896,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.54 4.742e-227 711.0
HFD2_k127_7807490_1 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003918 284.0
HFD2_k127_7807490_2 Belongs to the prokaryotic GSH synthase family K01920 GO:0003674,GO:0003824,GO:0004363,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042398,GO:0043043,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901564,GO:1901566,GO:1901576 6.3.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003778 275.0
HFD2_k127_7807490_3 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000002577 263.0
HFD2_k127_7807490_4 Domain of unknown function (DUF4010) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001407 273.0
HFD2_k127_7807490_5 COG1192 ATPases involved in chromosome partitioning - - - 0.000000000000000000000852 109.0
HFD2_k127_7835808_0 Oxidoreductase FAD-binding domain K00523,K02613 - 1.17.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005756 466.0
HFD2_k127_7835808_1 Phenylacetic acid catabolic protein K02611 - 1.14.13.149 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 317.0
HFD2_k127_7835808_2 Phenylacetic acid catabolic protein K02609 - 1.14.13.149 0.000000000000000000000000000000000000000000000000000000000000000000000384 239.0
HFD2_k127_7835808_3 Iron-sulfur cluster assembly protein K02612 - - 0.0000000000000000000000000000000000000000000000000000000000000004097 225.0
HFD2_k127_7837755_0 HI0933-like protein K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005585 415.0
HFD2_k127_7837755_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 329.0
HFD2_k127_7837755_2 - - - - 0.0000000000000000000000002733 112.0
HFD2_k127_7881780_0 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 411.0
HFD2_k127_7881780_1 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004613 337.0
HFD2_k127_7881780_2 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007183 309.0
HFD2_k127_7881780_3 protein conserved in bacteria K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 290.0
HFD2_k127_7881780_4 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000009292 216.0
HFD2_k127_7881780_5 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 0.00000000000000000000000000000000000003099 143.0
HFD2_k127_7881780_6 - - - - 0.0000000000000106 79.0
HFD2_k127_791047_0 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism K01961 - 6.3.4.14,6.4.1.2 3.847e-225 706.0
HFD2_k127_791047_1 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000000000000001237 172.0
HFD2_k127_791047_2 PFAM Uncharacterised protein family (UPF0153) - - - 0.0000000000000000000003485 100.0
HFD2_k127_791047_3 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0003504 43.0
HFD2_k127_7917532_0 Predicted membrane protein (DUF2207) - - - 2.283e-197 631.0
HFD2_k127_7917532_1 Predicted membrane protein (DUF2254) - - - 7.578e-196 625.0
HFD2_k127_7917532_2 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006011 469.0
HFD2_k127_7917532_3 Sigma factor regulator FecR K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 363.0
HFD2_k127_7917532_4 PFAM sugar isomerase (SIS) K07106 - 4.2.1.126 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 336.0
HFD2_k127_7917532_5 BadF/BadG/BcrA/BcrD ATPase family K18676 - 2.7.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001272 286.0
HFD2_k127_7917532_6 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003747 290.0
HFD2_k127_7917532_7 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000002834 237.0
HFD2_k127_7917532_8 Family of unknown function (DUF5367) - - - 0.0000003984 57.0
HFD2_k127_7930996_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007112 436.0
HFD2_k127_7930996_1 Belongs to the SAICAR synthetase family K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 410.0
HFD2_k127_7930996_10 Protein required for attachment to host cells - - - 0.0000009415 57.0
HFD2_k127_7930996_2 Ecdysteroid kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007364 366.0
HFD2_k127_7930996_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003628 307.0
HFD2_k127_7930996_4 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009748 284.0
HFD2_k127_7930996_5 Peptide methionine sulfoxide reductase K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000002024 253.0
HFD2_k127_7930996_6 BioY protein K03523 - - 0.000000000000000000000000000000000000004697 153.0
HFD2_k127_7930996_7 Domain of unknown function (DUF1476) - - - 0.000000000000000000000000000003874 123.0
HFD2_k127_7930996_8 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000001419 102.0
HFD2_k127_7930996_9 Putative esterase K07214 - - 0.0000003811 61.0
HFD2_k127_7943721_0 COG1522 Transcriptional regulators K05800 - - 0.00000000000000000000000000000000000000000000000000000000000000009557 226.0
HFD2_k127_7943721_1 Protein of unknown function (DUF3754) - - - 0.000000000000000000000000000000000000000000000000000000000000001512 237.0
HFD2_k127_7943721_2 Peptidase C13 family - - - 0.0000000000000000000000000000000000000000000000925 181.0
HFD2_k127_7953312_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 3.34e-220 696.0
HFD2_k127_7953312_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 1.445e-198 629.0
HFD2_k127_7953312_2 Belongs to the GPI family K01810 - 5.3.1.9 0.0001651 44.0
HFD2_k127_7970631_0 Belongs to the sigma-70 factor family K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 359.0
HFD2_k127_7970631_1 to M. xanthus CarD K07736 - - 0.00000000000000000000000000000000000000000000000000000000000000000003771 235.0
HFD2_k127_7970631_2 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000001726 75.0
HFD2_k127_7970631_3 Staphylococcal nuclease homologues - - - 0.0000001035 63.0
HFD2_k127_7972037_0 Belongs to the DEAD box helicase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 540.0
HFD2_k127_8023220_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1124.0
HFD2_k127_8023220_1 ATP-dependent helicase K03579 - 3.6.4.13 6.189e-278 876.0
HFD2_k127_8023220_10 EamA-like transporter family K15268 - - 0.00000000000000000000000000000000000000000000000000000000000002128 225.0
HFD2_k127_8023220_11 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000000000000000003622 211.0
HFD2_k127_8023220_12 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000692 189.0
HFD2_k127_8023220_13 - - - - 0.00000000000000000000000001041 117.0
HFD2_k127_8023220_14 - - - - 0.0000000000000002429 91.0
HFD2_k127_8023220_15 Peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.0007783 46.0
HFD2_k127_8023220_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005404 534.0
HFD2_k127_8023220_3 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 479.0
HFD2_k127_8023220_4 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 461.0
HFD2_k127_8023220_5 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004963 362.0
HFD2_k127_8023220_6 threonine dehydratase K01754 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006520,GO:0006563,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016841,GO:0016853,GO:0016854,GO:0016855,GO:0017144,GO:0018249,GO:0019538,GO:0019752,GO:0019842,GO:0030170,GO:0030378,GO:0030848,GO:0036094,GO:0036211,GO:0036361,GO:0042219,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046416,GO:0046437,GO:0046872,GO:0047661,GO:0048037,GO:0050662,GO:0070178,GO:0070179,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901607 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 331.0
HFD2_k127_8023220_7 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000563 261.0
HFD2_k127_8023220_8 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000001058 257.0
HFD2_k127_8023220_9 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000000002058 224.0
HFD2_k127_8026093_0 enoyl-CoA hydratase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001042 272.0
HFD2_k127_8026093_1 Phenylacetic acid catabolic protein K02609 - 1.14.13.149 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001969 267.0
HFD2_k127_8026093_2 Thioesterase superfamily K02614 - - 0.00000000000000000000000000000000000000000008344 168.0
HFD2_k127_8029319_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003582 368.0
HFD2_k127_8029319_1 Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 310.0
HFD2_k127_8029319_2 Dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000003164 198.0
HFD2_k127_8029319_3 Esterase PHB depolymerase - - - 0.00000000000000000000000000009381 133.0
HFD2_k127_8029319_4 esterase K03932 - - 0.000000000000000000002159 109.0
HFD2_k127_8029319_5 SnoaL-like polyketide cyclase - - - 0.0000000000000000001944 90.0
HFD2_k127_8029319_6 Curlin associated repeat K04335 - - 0.000000000000000001274 95.0
HFD2_k127_8029319_7 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000009413 79.0
HFD2_k127_8029319_9 SnoaL-like polyketide cyclase - - - 0.00000008941 58.0
HFD2_k127_8041671_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 3.773e-207 654.0
HFD2_k127_8041671_1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K14981 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000007367 154.0
HFD2_k127_8041671_2 - - - - 0.00000000000000000000000000000001101 132.0
HFD2_k127_8049792_0 2-deoxycytidine 5-triphosphate deaminase K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002673 427.0
HFD2_k127_8049792_1 Transcriptional regulatory protein, C terminal K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 330.0
HFD2_k127_8049792_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000001283 230.0
HFD2_k127_8049792_3 PFAM GumN family protein K09973 - - 0.00000000000000000000000000000000000000000000000000000004466 218.0
HFD2_k127_8049792_4 protein affecting Mg2 Co2 transport K06195 - - 0.0000000000000000000000000000000000000000001411 165.0
HFD2_k127_8049792_5 EF hand - - - 0.000000000000000000000000000002068 130.0
HFD2_k127_8049792_6 EF hand - - - 0.0000009846 57.0
HFD2_k127_8098453_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006624 422.0
HFD2_k127_8098453_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003715 323.0
HFD2_k127_8098453_2 FCD - - - 0.000000000000000000000000000000000000000000000000000000000000000008203 232.0
HFD2_k127_8109505_0 Belongs to the beta-ketoacyl-ACP synthases family K00647 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.41 7.37e-201 631.0
HFD2_k127_8109505_1 SMART alpha amylase catalytic sub domain K01187 - 3.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 604.0
HFD2_k127_8109505_2 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00015 - 1.1.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000434 546.0
HFD2_k127_8109505_3 HxlR-like helix-turn-helix - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007626 355.0
HFD2_k127_8109505_4 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002413 286.0
HFD2_k127_8109505_5 Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length K01716 - 4.2.1.59,5.3.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000004763 264.0
HFD2_k127_8109505_6 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000004635 231.0
HFD2_k127_8109505_7 EthD domain - - - 0.00000000000000000000000000000000002307 143.0
HFD2_k127_8109505_8 Bacterial SH3 domain K01876 - 6.1.1.12 0.000000000000000000000000000000007887 141.0
HFD2_k127_8109505_9 - - - - 0.000000000000000000000000000000008835 138.0
HFD2_k127_8135963_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 8.152e-259 816.0
HFD2_k127_8135963_1 COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases K00101 GO:0002218,GO:0002253,GO:0002376,GO:0002682,GO:0002684,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006950,GO:0006952,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009058,GO:0009605,GO:0009607,GO:0009617,GO:0009987,GO:0010204,GO:0016999,GO:0017000,GO:0017144,GO:0023052,GO:0031347,GO:0031349,GO:0042579,GO:0042742,GO:0042743,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044249,GO:0044424,GO:0044444,GO:0044464,GO:0045088,GO:0045089,GO:0048518,GO:0048583,GO:0048584,GO:0050665,GO:0050776,GO:0050778,GO:0050789,GO:0050794,GO:0050896,GO:0051186,GO:0051188,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0072593,GO:0080134,GO:0098542,GO:1903409 1.1.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 473.0
HFD2_k127_8135963_2 HemY protein N-terminus K02498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009521 297.0
HFD2_k127_8135963_3 - - - - 0.00000000000000000000000000000000000000000000000000000007664 206.0
HFD2_k127_8135963_4 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.00000000000000000001914 103.0
HFD2_k127_8135963_5 Chromate resistance exported protein - - - 0.00000000000000005165 84.0
HFD2_k127_8135963_6 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000004379 68.0
HFD2_k127_822193_0 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007192 572.0
HFD2_k127_822193_1 leucine aminopeptidase 3 K09611,K11142 GO:0003674,GO:0003824,GO:0004177,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009056,GO:0009057,GO:0016787,GO:0019538,GO:0030163,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.11.1,3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 523.0
HFD2_k127_822193_2 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 350.0
HFD2_k127_822193_3 Predicted permease YjgP/YjgQ family K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000304 289.0
HFD2_k127_822193_4 Chaperone SurA K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001145 289.0
HFD2_k127_822193_5 Predicted permease YjgP/YjgQ family K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001008 271.0
HFD2_k127_822193_6 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000009166 228.0
HFD2_k127_822193_7 DNA polymerase III K02339 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000001045 199.0
HFD2_k127_822193_8 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00000000000000003644 83.0
HFD2_k127_8235706_0 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 586.0
HFD2_k127_8235706_1 MatE - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005816 494.0
HFD2_k127_8235706_10 phosphoribosyltransferase K00760 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000105 203.0
HFD2_k127_8235706_11 zinc-ribbon domain - - - 0.000000000000000000000000000000000000000000004935 175.0
HFD2_k127_8235706_12 cell division ATP-binding protein FtsE K09812 - - 0.0000000000000000000000000000000000000000004454 166.0
HFD2_k127_8235706_13 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000001968 158.0
HFD2_k127_8235706_14 Thioredoxin-like - - - 0.00000000000000000000000000000000000657 144.0
HFD2_k127_8235706_15 NYN domain - - - 0.00000000000000000000000000000000017 144.0
HFD2_k127_8235706_16 Protein of unknown function (DUF1109) - - - 0.00000000000000000000000001478 122.0
HFD2_k127_8235706_17 Heat shock 70 kDa protein - - - 0.0000000001981 75.0
HFD2_k127_8235706_18 - - - - 0.0005343 46.0
HFD2_k127_8235706_2 Electron transfer flavoprotein K03522 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 438.0
HFD2_k127_8235706_3 Dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005904 432.0
HFD2_k127_8235706_4 Electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 365.0
HFD2_k127_8235706_5 Prephenate dehydratase K04518 - 4.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003874 362.0
HFD2_k127_8235706_6 Domain of unknown function (DUF4175) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 317.0
HFD2_k127_8235706_7 Protein of unknown function (DUF938) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002044 250.0
HFD2_k127_8235706_8 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000255 252.0
HFD2_k127_8235706_9 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.00000000000000000000000000000000000000000000000000000000000002032 219.0
HFD2_k127_8247345_0 Belongs to the GSP D family K02280 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 346.0
HFD2_k127_8247345_1 Putative Flp pilus-assembly TadE/G-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 323.0
HFD2_k127_8247345_2 Pilus assembly protein CpaB K02279 - - 0.000000000000000000000000000000000000000000000000000004221 200.0
HFD2_k127_8247345_3 PFAM TadE family protein - - - 0.0000007763 58.0
HFD2_k127_8261053_0 COG2373 Large extracellular alpha-helical protein K06894 - - 0.0 1234.0
HFD2_k127_8261053_1 4-coumarate--CoA - - - 5.836e-239 753.0
HFD2_k127_8261053_10 Histidine kinase - - - 0.000001615 60.0
HFD2_k127_8261053_2 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K11745,K11747 - - 1.57e-237 752.0
HFD2_k127_8261053_3 COG0076 Glutamate decarboxylase and related PLP-dependent proteins K01593 - 4.1.1.105,4.1.1.28 1.181e-202 640.0
HFD2_k127_8261053_4 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000993 407.0
HFD2_k127_8261053_5 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 407.0
HFD2_k127_8261053_6 COG1352 Methylase of chemotaxis methyl-accepting proteins K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000001905 201.0
HFD2_k127_8261053_7 Chemotaxis protein CheY K03413 - - 0.00000000000000000000000000000000000000000000000000002037 190.0
HFD2_k127_8261053_8 Uncharacterized protein conserved in bacteria (DUF2188) - - - 0.000000000000000000000000000004979 121.0
HFD2_k127_8261053_9 signal transduction histidine kinase K13588 - - 0.00000000000000000000000000008907 124.0
HFD2_k127_8262068_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 4.442e-223 701.0
HFD2_k127_8262068_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007292 583.0
HFD2_k127_8262068_10 Colicin V production protein K03558 - - 0.0000000000000000152 92.0
HFD2_k127_8262068_2 HI0933-like protein K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 468.0
HFD2_k127_8262068_3 KR domain - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0008152,GO:0009056,GO:0016491,GO:0044464,GO:0055114,GO:0071704,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000007835 249.0
HFD2_k127_8262068_4 ABC transporter, ATP-binding protein K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000005583 233.0
HFD2_k127_8262068_5 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.0000000000000000000000000000000000000000000000000000000000000000001507 232.0
HFD2_k127_8262068_6 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000004004 237.0
HFD2_k127_8262068_7 PKHD-type hydroxylase K07336 - - 0.00000000000000000000000000000000000000000000000000000000002402 212.0
HFD2_k127_8262068_8 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000005075 193.0
HFD2_k127_8262068_9 - - - - 0.000000000000000003819 91.0
HFD2_k127_8313934_0 COG2902 NAD-specific glutamate dehydrogenase K15371 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0008150,GO:0008152,GO:0016491,GO:0016638,GO:0016639,GO:0055114 1.4.1.2 0.0 1191.0
HFD2_k127_8313934_1 dehydratase K12658,K18384 - 4.2.1.77,5.1.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009679 520.0
HFD2_k127_8313934_2 Belongs to the peptidase M24B family K01271 - 3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 479.0
HFD2_k127_8313934_3 Belongs to the DapA family K01714,K21062 - 3.5.4.22,4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006376 458.0
HFD2_k127_8313934_4 FAD dependent oxidoreductase K00285 - 1.4.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 435.0
HFD2_k127_8313934_5 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 408.0
HFD2_k127_8313934_6 Sulfite exporter TauE/SafE - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 339.0
HFD2_k127_8318936_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 8.367e-203 644.0
HFD2_k127_8318936_1 COG0438 Glycosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009895 501.0
HFD2_k127_8318936_2 Belongs to the Orn Lys Arg decarboxylase class-II family K01581 - 4.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 479.0
HFD2_k127_8318936_3 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 366.0
HFD2_k127_8318936_4 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005134 309.0
HFD2_k127_8318936_5 Phosphate transport system permease K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001822 282.0
HFD2_k127_8318936_6 Transcriptional regulator K13643 - - 0.0000000000000000000000000000000000000005825 157.0
HFD2_k127_8318936_7 PFAM phosphate-selective porin O and P K07221 - - 0.000000000000000000000000000000005256 145.0
HFD2_k127_8344919_0 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.00000000000000000000000000000000000000000000000000000000000000000006117 245.0
HFD2_k127_8344919_1 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000005997 139.0
HFD2_k127_8344919_2 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides K01465 - 3.5.2.3 0.00000000000000000000000000005019 118.0
HFD2_k127_8344919_3 Periplasmic Protein - GO:0003674,GO:0004857,GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0016020,GO:0019867,GO:0030234,GO:0030312,GO:0030313,GO:0031975,GO:0043086,GO:0044092,GO:0044462,GO:0044464,GO:0050790,GO:0060241,GO:0065007,GO:0065009,GO:0071944,GO:0098772 - 0.00007475 49.0
HFD2_k127_8344919_4 Tetratricopeptide repeat K09527 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0030544,GO:0031072,GO:0051084,GO:0051085,GO:0061077 - 0.000774 51.0
HFD2_k127_83518_0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 8.267e-223 704.0
HFD2_k127_83518_1 Pyridoxal-dependent decarboxylase K13745 - 4.1.1.86 3.917e-198 625.0
HFD2_k127_83518_2 Belongs to the heat shock protein 70 family K04046 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006393 501.0
HFD2_k127_83518_3 Proton-conducting membrane transporter K12141 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 287.0
HFD2_k127_83518_4 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001155 255.0
HFD2_k127_83518_5 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins - - - 0.000000000000000000000000000000000000000000000000000000000001231 218.0
HFD2_k127_83518_6 SMART regulatory protein, ArsR - - - 0.00000000000000000000001465 104.0
HFD2_k127_83518_7 Domain of unknown function (DU1801) - - - 0.00000000000000001983 91.0
HFD2_k127_83518_8 Protein of unknown function (DUF983) - - - 0.00000000000000709 84.0
HFD2_k127_837462_0 COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000006862 222.0
HFD2_k127_837462_1 transcriptional regulator - - - 0.0000000000000000000000000000000000000003805 156.0
HFD2_k127_837462_2 Sulfatase - - - 0.00000000000000000000000739 103.0
HFD2_k127_8377502_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032940,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 480.0
HFD2_k127_8377502_1 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004915 447.0
HFD2_k127_8377502_2 Protein of unknown function (DUF1036) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006251 322.0
HFD2_k127_8377502_3 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001076 250.0
HFD2_k127_8377502_4 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000000000000000003172 115.0
HFD2_k127_8377502_5 Ribosomal protein L34 K02914 - - 0.000000000000008379 74.0
HFD2_k127_8378297_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 5.049e-235 741.0
HFD2_k127_8378297_1 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000806 403.0
HFD2_k127_8378297_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009806 283.0
HFD2_k127_8378297_3 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.000000000000000000000000000000000000006003 154.0
HFD2_k127_8378297_4 Peptidase, M28 - - - 0.00000000000000000000000000000000002538 136.0
HFD2_k127_8383976_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 2.753e-307 971.0
HFD2_k127_8383976_1 peptidase S9A prolyl oligopeptidase domain protein beta-propeller K01354 - 3.4.21.83 2.072e-300 935.0
HFD2_k127_8383976_10 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000001537 112.0
HFD2_k127_8383976_11 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000009512 101.0
HFD2_k127_8383976_12 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.0000000000000002878 83.0
HFD2_k127_8383976_2 cytochrome c biogenesis protein - - - 3.348e-221 699.0
HFD2_k127_8383976_3 carboxylase, alpha K01965 - 6.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 593.0
HFD2_k127_8383976_4 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 GO:0000166,GO:0000302,GO:0000305,GO:0003674,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0010035,GO:0017076,GO:0019725,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045454,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0065007,GO:0065008,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901700 1.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009302 525.0
HFD2_k127_8383976_5 Anion-transporting ATPase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006103 299.0
HFD2_k127_8383976_6 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 295.0
HFD2_k127_8383976_7 PFAM MaoC domain protein dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000001236 216.0
HFD2_k127_8383976_8 protein serine/threonine phosphatase activity - - - 0.00000000000000000000000000000000000000000757 164.0
HFD2_k127_8383976_9 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000000000000000007511 120.0
HFD2_k127_8417604_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1434.0
HFD2_k127_8417604_1 FAD-dependent pyridine K17218 - 1.8.5.4 1.098e-219 687.0
HFD2_k127_8417604_10 Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000002054 211.0
HFD2_k127_8417604_11 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000001932 184.0
HFD2_k127_8417604_12 Proton-conducting membrane transporter K05568 - - 0.00000000000000000000000000000000000000000000002126 192.0
HFD2_k127_8417604_13 Thioredoxin K03672 - 1.8.1.8 0.00000000000000000000000000000000000000000001627 166.0
HFD2_k127_8417604_14 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000000004203 162.0
HFD2_k127_8417604_15 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.0000000000000000000000000000000000000001975 152.0
HFD2_k127_8417604_16 COG0811 Biopolymer transport proteins K03562 - - 0.000000000000000000000000000000000000001146 158.0
HFD2_k127_8417604_17 Fe-S metabolism associated K02426 - - 0.00000000000000000000000000004017 118.0
HFD2_k127_8417604_18 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000002769 118.0
HFD2_k127_8417604_19 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000002976 117.0
HFD2_k127_8417604_2 chloride channel K03281 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006077 518.0
HFD2_k127_8417604_20 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.00000000000000000000000001888 114.0
HFD2_k127_8417604_21 Protein of unknown function (DUF2892) - - - 0.0000000000000000000000001146 109.0
HFD2_k127_8417604_22 Belongs to the BolA IbaG family - - - 0.0000000000000000000000001509 107.0
HFD2_k127_8417604_23 Protein of unknown function (DUF2892) - - - 0.000000000000000000000003106 103.0
HFD2_k127_8417604_24 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000000000000000000006743 111.0
HFD2_k127_8417604_25 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.000000000000000000002493 99.0
HFD2_k127_8417604_26 PFAM NADH Ubiquinone plastoquinone (complex I) K05561,K05568 - - 0.0000000000000006343 91.0
HFD2_k127_8417604_27 COG0593 ATPase involved in DNA replication initiation - - - 0.0000000000009464 71.0
HFD2_k127_8417604_28 MnhG PhaG family monovalent cation proton antiporter K05571 - - 0.0000000001836 68.0
HFD2_k127_8417604_29 lactoylglutathione lyase activity - - - 0.000000002478 64.0
HFD2_k127_8417604_3 Uncharacterised protein conserved in bacteria (DUF2336) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 320.0
HFD2_k127_8417604_30 OsmC-like protein - - - 0.000000003205 60.0
HFD2_k127_8417604_31 DNA-binding transcription factor activity - - - 0.00000002623 64.0
HFD2_k127_8417604_32 SEC-C motif - - - 0.000001164 51.0
HFD2_k127_8417604_33 Multiple resistance and pH regulation protein F K05570 - - 0.00002281 51.0
HFD2_k127_8417604_34 COG2111 Multisubunit Na H antiporter, MnhB subunit K05566 - - 0.0002709 51.0
HFD2_k127_8417604_4 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003916 301.0
HFD2_k127_8417604_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006145 270.0
HFD2_k127_8417604_6 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001432 264.0
HFD2_k127_8417604_7 COG0651 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit K00341,K05568 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000005352 235.0
HFD2_k127_8417604_8 - - - - 0.000000000000000000000000000000000000000000000000000000000005801 220.0
HFD2_k127_8417604_9 - - - - 0.00000000000000000000000000000000000000000000000000001434 197.0
HFD2_k127_8423087_0 Vacuole effluxer Atg22 like K06902 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 415.0
HFD2_k127_8423087_1 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 389.0
HFD2_k127_8423087_2 Alpha beta hydrolase fold family protein K01066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000317 319.0
HFD2_k127_8423087_3 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000001265 166.0
HFD2_k127_8444011_0 AMP-binding enzyme C-terminal domain K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 335.0
HFD2_k127_8444011_1 - - - - 0.000000000000000000000000000000000000009919 153.0
HFD2_k127_8446407_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00410,K00412 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005882 595.0
HFD2_k127_8446407_1 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007428 428.0
HFD2_k127_8446407_2 CAAX protease self-immunity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 327.0
HFD2_k127_8446407_3 cytochrome c1 K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002764 269.0
HFD2_k127_8446407_4 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.000000000000000000000000000000000000000000000000000000000000000256 225.0
HFD2_k127_8446407_5 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.00000000000000000000000000000000000000000000000000874 185.0
HFD2_k127_8446407_6 Poly A polymerase head domain K00970 - 2.7.7.19 0.0000000000000000000000000000000000000000000004326 169.0
HFD2_k127_8446407_7 MarR family - - - 0.000000000000000000000000000000004646 133.0
HFD2_k127_8446407_8 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.000000000000001118 85.0
HFD2_k127_8450139_0 Histidine kinase K13587 - 2.7.13.3 2.89e-204 664.0
HFD2_k127_8450139_1 Bacterial protein of unknown function (DUF885) - - - 1.237e-194 627.0
HFD2_k127_8450139_10 Nickel/cobalt transporter regulator - - - 0.0000000000000000005672 93.0
HFD2_k127_8450139_11 Flagellar hook-basal body complex protein FliE K02408 - - 0.00000000000000001889 88.0
HFD2_k127_8450139_12 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit - - - 0.00000000001161 66.0
HFD2_k127_8450139_13 flagellar K02418 - - 0.00000000001579 68.0
HFD2_k127_8450139_14 UPF0391 membrane protein - - - 0.000000005761 66.0
HFD2_k127_8450139_2 oxidoreductase K05275 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 417.0
HFD2_k127_8450139_3 Belongs to the Glu Leu Phe Val dehydrogenases family K00263 - 1.4.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 340.0
HFD2_k127_8450139_4 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 329.0
HFD2_k127_8450139_5 Plays a role in the flagellum-specific transport system K02419 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006761 294.0
HFD2_k127_8450139_6 Role in flagellar biosynthesis K02421 - - 0.0000000000000000000000000000000000000000000000000000000002564 213.0
HFD2_k127_8450139_7 Belongs to the flagella basal body rod proteins family K02388 - - 0.00000000000000000000000000000000000000005864 154.0
HFD2_k127_8450139_8 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.00000000000000000000000000000004322 129.0
HFD2_k127_8450139_9 Role in flagellar biosynthesis K02420 - - 0.0000000000000000000000002684 107.0
HFD2_k127_8457797_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K00557,K03215 - 2.1.1.190,2.1.1.35 0.0000000000000000000000000000000000000000000000000000005392 198.0
HFD2_k127_8457797_1 Appr-1'-p processing enzyme - - - 0.0000000000000000000000000000000000002013 147.0
HFD2_k127_8457797_2 - - - - 0.000000000000000007519 90.0
HFD2_k127_8457797_4 Domain of unknown function (DUF1963) - - - 0.00004807 54.0
HFD2_k127_8503157_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 447.0
HFD2_k127_8503157_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000279 269.0
HFD2_k127_8503157_2 Forms part of the polypeptide exit tunnel K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000004311 249.0
HFD2_k127_8503157_3 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000000000001228 168.0
HFD2_k127_8503157_4 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000008762 167.0
HFD2_k127_8503157_5 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000001753 139.0
HFD2_k127_8503157_6 Ribosomal protein S3, C-terminal domain K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000009685 50.0
HFD2_k127_8503545_0 The M ring may be actively involved in energy transduction K02409 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003383 363.0
HFD2_k127_8503545_1 Protein of unknown function (DUF1153) - - - 0.00000000000000000000000000000009676 124.0
HFD2_k127_8543371_0 A G-specific adenine glycosylase K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002039 249.0
HFD2_k127_8543371_1 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000009139 226.0
HFD2_k127_8543371_2 Cyclic nucleotide-monophosphate binding domain K10914 - - 0.000000000000000000000000000000000000000000000000000000000001465 216.0
HFD2_k127_8543371_3 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000000000000000000000003497 188.0
HFD2_k127_8543371_4 Belongs to the N(4) N(6)-methyltransferase family K13581 - 2.1.1.72 0.00000000000000000000000000000000000000009213 154.0
HFD2_k127_8546737_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 424.0
HFD2_k127_8546737_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000001044 235.0
HFD2_k127_8546737_2 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.00000000000000000000000000215 115.0
HFD2_k127_8546737_3 - - - - 0.00000000000000000001735 91.0
HFD2_k127_8546737_4 beta-1,4-mannooligosaccharide phosphorylase - - - 0.0000000000003236 69.0
HFD2_k127_8553352_0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007853 321.0
HFD2_k127_8553352_1 Periplasmic binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000247 254.0
HFD2_k127_8553352_2 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000001001 164.0
HFD2_k127_8583799_0 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003842 464.0
HFD2_k127_8583799_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002328 276.0
HFD2_k127_8583799_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000001048 121.0
HFD2_k127_8583799_3 phosphoglycerate mutase - - - 0.000000000000001345 84.0
HFD2_k127_8583799_4 - - - - 0.0004084 48.0
HFD2_k127_8595167_0 COG0642 Signal transduction histidine kinase K14980 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009801 437.0
HFD2_k127_8595167_1 M61 glycyl aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 382.0
HFD2_k127_8595167_2 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K14981 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006964 327.0
HFD2_k127_8595167_3 Conserved TM helix - - - 0.000000000000000000000000000000000000000000000000000000000000009225 231.0
HFD2_k127_8595167_4 COG2893 Phosphotransferase system, mannose fructose-specific component IIA K02793 - 2.7.1.191 0.00000000000000000000000000000000000000000000000003165 181.0
HFD2_k127_8595167_5 Transglycosylase associated protein - - - 0.0000000000000000000000005871 106.0
HFD2_k127_8595167_6 COG1925 Phosphotransferase system, HPr-related proteins K11189 - - 0.000000000000000007107 88.0
HFD2_k127_8595167_7 PQ loop repeat K15383 - - 0.0000000003749 62.0
HFD2_k127_8607181_0 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 506.0
HFD2_k127_8607181_1 Iron-containing redox enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 364.0
HFD2_k127_8607181_2 Methyltransferase small domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001578 265.0
HFD2_k127_8607181_3 ligase activity - - - 0.00000000000000000000000000000000000000000000001705 175.0
HFD2_k127_8607181_4 transcriptional regulator - - - 0.00000000000000000000000003651 115.0
HFD2_k127_8607181_5 - - - - 0.000002976 59.0
HFD2_k127_8626618_0 COG4962 Flp pilus assembly protein, ATPase CpaF K02283 - - 3.342e-233 729.0
HFD2_k127_8626618_1 Belongs to the peptidase M17 family K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003924 476.0
HFD2_k127_8626618_10 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000164 190.0
HFD2_k127_8626618_11 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000002298 188.0
HFD2_k127_8626618_12 TadE-like protein K02651 - - 0.00000000000000000000000000000000000007327 149.0
HFD2_k127_8626618_13 COG3474 Cytochrome c2 K08738 - - 0.0000000000000000000000000000000001356 143.0
HFD2_k127_8626618_14 Pilus assembly protein CpaB K02279 - - 0.00000000000000000000000000000002315 136.0
HFD2_k127_8626618_15 MarR family - - - 0.000000000000000000000000000002503 131.0
HFD2_k127_8626618_16 Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations K01241 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008714,GO:0016787,GO:0016798,GO:0016799,GO:0044424,GO:0044444,GO:0044464 3.2.2.4 0.000000000000000000000000000004603 124.0
HFD2_k127_8626618_17 peptidase K02278 - 3.4.23.43 0.00000000000000000000000000002563 123.0
HFD2_k127_8626618_18 Pilus biogenesis CpaD protein (pilus_cpaD) K02281 - - 0.00000000000000000000000001652 118.0
HFD2_k127_8626618_19 - - - - 0.00000000000000000001558 98.0
HFD2_k127_8626618_2 Pilus assembly protein K02282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 447.0
HFD2_k127_8626618_20 COG4964 Flp pilus assembly protein, secretin CpaC - - - 0.0000000000000000001121 94.0
HFD2_k127_8626618_21 CAAX protease self-immunity K07052 - - 0.0000000000000000001348 98.0
HFD2_k127_8626618_22 - - - - 0.00000000000003288 85.0
HFD2_k127_8626618_23 Flp pilus assembly protein, pilin Flp K02651 - - 0.000000000002365 68.0
HFD2_k127_8626618_24 PFAM TadE family protein - - - 0.0000000001755 71.0
HFD2_k127_8626618_25 helix_turn_helix, arabinose operon control protein - - - 0.0000001064 63.0
HFD2_k127_8626618_3 Pilus formation protein N terminal region K02280 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005004 428.0
HFD2_k127_8626618_4 type II secretion system protein K12511 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 344.0
HFD2_k127_8626618_5 Secretion system protein K12510 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003916 301.0
HFD2_k127_8626618_6 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000002345 260.0
HFD2_k127_8626618_7 dioxygenase of extradiol dioxygenase family K06991 - - 0.00000000000000000000000000000000000000000000000000000000000006472 215.0
HFD2_k127_8626618_8 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000002473 221.0
HFD2_k127_8626618_9 alpha/beta hydrolase fold K01066 - - 0.0000000000000000000000000000000000000000000000000000000000007695 217.0
HFD2_k127_8631571_0 Predicted membrane protein (DUF2254) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 595.0
HFD2_k127_8631571_1 Pfam Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000004791 198.0
HFD2_k127_8631571_2 Family of unknown function (DUF5367) - - - 0.00000000003169 69.0
HFD2_k127_8636576_0 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004009 431.0
HFD2_k127_8636576_1 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 338.0
HFD2_k127_8636576_2 Auxin efflux carrier family protein K07088 - - 0.00000000000000000000000000000000000000000000000000000000000002861 226.0
HFD2_k127_8636576_3 - - - - 0.0000000000000001102 83.0
HFD2_k127_8661793_0 peptidase M13 K07386 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005714 308.0
HFD2_k127_8661793_1 - - - - 0.0000007538 59.0
HFD2_k127_8661793_2 nuclear chromosome segregation - - - 0.00001784 57.0
HFD2_k127_866369_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088,K00364 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205,1.7.1.7 2.441e-209 661.0
HFD2_k127_866369_1 16S rRNA methyltransferase RsmB/F K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 446.0
HFD2_k127_866369_2 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 343.0
HFD2_k127_866369_3 Ppx GppA K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009286 298.0
HFD2_k127_866369_4 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.0000000000000000000000000000000000000000000000000000000000000000000000000004222 262.0
HFD2_k127_8666497_0 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000539 469.0
HFD2_k127_8666497_1 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 374.0
HFD2_k127_8666497_2 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000287 260.0
HFD2_k127_8666497_3 COG0859 ADP-heptose LPS heptosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001005 257.0
HFD2_k127_8666497_4 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000006048 243.0
HFD2_k127_8666497_5 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000001293 153.0
HFD2_k127_8666497_6 - - - - 0.000000000000000000000000003361 114.0
HFD2_k127_8666497_7 Divergent PAP2 family - - - 0.0002378 45.0
HFD2_k127_8680399_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 497.0
HFD2_k127_8680399_1 membrane protein of uknown function UCP014873 - - - 0.00000000000000000000000000000000000000000000000000000007883 201.0
HFD2_k127_8680399_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00046 - 1.1.1.69 0.0000000000000000000000000000000000000000000002909 175.0
HFD2_k127_8680399_3 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141 - 0.00000000000000000000000000000001144 129.0
HFD2_k127_8686643_0 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 8.934e-313 971.0
HFD2_k127_8686643_1 e3 binding domain K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 436.0
HFD2_k127_8686643_2 PFAM Aminotransferase class I and II K00832 - 2.6.1.57 0.000000000000000000000000000000000000000000000000001859 188.0
HFD2_k127_8686643_3 Copper chaperone PCu(A)C K09796 - - 0.0000000000000000000000001448 111.0
HFD2_k127_8686643_4 transcriptional K03719 - - 0.000000000000000000000009912 107.0
HFD2_k127_8686643_5 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 0.0000000000000006027 85.0
HFD2_k127_8704334_0 Belongs to the aspartokinase family K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004555 542.0
HFD2_k127_8704334_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 293.0
HFD2_k127_8704334_2 amidohydrolase K01459,K11206 - 3.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005897 281.0
HFD2_k127_8704334_3 Belongs to the PEP-utilizing enzyme family K08484 - 2.7.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002815 273.0
HFD2_k127_8704334_4 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000002284 252.0
HFD2_k127_8704334_5 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002589 237.0
HFD2_k127_8704334_6 protein conserved in bacteria - - - 0.0000000000000000000000000000000001252 138.0
HFD2_k127_8704334_7 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.000000000000000000000000000005648 120.0
HFD2_k127_885335_0 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000002053 270.0
HFD2_k127_885335_1 Malic enzyme K00029 - 1.1.1.40 0.000000145 54.0
HFD2_k127_901710_0 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 587.0
HFD2_k127_901710_1 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007443 378.0
HFD2_k127_901710_2 Aerotolerance regulator N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003966 266.0
HFD2_k127_901710_3 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000000000001299 192.0
HFD2_k127_901710_4 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000005057 128.0
HFD2_k127_906390_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 0.0 1034.0
HFD2_k127_906390_1 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 595.0
HFD2_k127_906390_2 Glycosyl transferase, family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009829 443.0
HFD2_k127_906390_4 - - - - 0.0000000000000000000000000000000000000000000000108 177.0
HFD2_k127_906390_5 Glyoxalase-like domain - - - 0.000000000000000000000000000000007095 132.0
HFD2_k127_906390_6 Succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.00000000000000000000000000000007476 129.0
HFD2_k127_906390_7 COG2142 Succinate dehydrogenase, hydrophobic anchor subunit K00242 - - 0.000000000000000000004557 107.0
HFD2_k127_906390_8 - - - - 0.0000000000001341 77.0
HFD2_k127_906390_9 Tetratricopeptide repeat - - - 0.000000132 63.0
HFD2_k127_925065_0 serine acetyltransferase K00640 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009314,GO:0009333,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 321.0
HFD2_k127_925065_1 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000000004241 196.0
HFD2_k127_925065_3 Rhomboid family - - - 0.00000000000000001815 91.0
HFD2_k127_926226_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003326 538.0
HFD2_k127_926226_1 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005567 415.0
HFD2_k127_926226_10 Protein of unknown function (DUF1697) - - - 0.000000000000000000000000000000001983 136.0
HFD2_k127_926226_11 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000000002518 127.0
HFD2_k127_926226_12 Belongs to the ompA family - - - 0.000000000000000000000006032 112.0
HFD2_k127_926226_13 - - - - 0.00000000000008045 80.0
HFD2_k127_926226_2 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity K03366,K13370 - 1.1.1.239,1.1.1.304,1.1.1.62,1.1.1.76 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000075 352.0
HFD2_k127_926226_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 349.0
HFD2_k127_926226_4 COG0767 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000058 347.0
HFD2_k127_926226_5 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008243 282.0
HFD2_k127_926226_6 Binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000000000000000000000000000000008489 218.0
HFD2_k127_926226_7 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000004467 165.0
HFD2_k127_926226_8 ABC transporter, ATP-binding protein K02065 - - 0.0000000000000000000000000000000000000000006324 162.0
HFD2_k127_926226_9 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000001659 142.0
HFD2_k127_938366_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000008776 156.0
HFD2_k127_992561_0 adenylosuccinate synthase activity K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 1.61e-213 671.0
HFD2_k127_992561_1 Patatin-like phospholipase - - - 0.00000000000000000000000000000000000000000000000000000000001001 224.0
HFD2_k127_992561_2 - - - - 0.000001052 57.0
HFD2_k127_994703_0 epimerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 396.0
HFD2_k127_994703_1 Alkyl sulfatase dimerisation - - - 0.000000000000000000000000000000000000000000000000000000000000000000009657 238.0
HFD2_k127_994703_2 - - - - 0.000000000000000000000000000000000000000000001167 168.0
HFD2_k127_994703_3 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000001795 102.0
HFD2_k127_994703_4 - - - - 0.0000000000000004283 85.0
HFD2_k127_994703_5 - - - - 0.000752 48.0