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Overview

ID MAG01665
Name HFD2_bin.59
Sample SMP0044
Taxonomy
Kingdom Bacteria
Phylum Eisenbacteria
Class RBG-16-71-46
Order RBG-16-71-46
Family RBG-16-71-46
Genus JAIOPA01
Species
Assembly information
Completeness (%) 67.93
Contamination (%) 1.67
GC content (%) 72.0
N50 (bp) 18,106
Genome size (bp) 3,411,672

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2593

Gene name Description KEGG GOs EC E-value Score Sequence
HFD2_k127_100806_0 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K12452,K13328 - 1.17.1.1,4.2.1.164 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 562.0
HFD2_k127_100806_1 Major facilitator superfamily K08151 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004356 475.0
HFD2_k127_100806_10 ABC transporter K06158 - - 0.00004901 49.0
HFD2_k127_100806_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007686 427.0
HFD2_k127_100806_3 PFAM NAD-dependent epimerase dehydratase K01709 - 4.2.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004886 396.0
HFD2_k127_100806_4 Glucose-1-phosphate cytidylyltransferase K00978 - 2.7.7.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 320.0
HFD2_k127_100806_5 BMC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001288 256.0
HFD2_k127_100806_6 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000001096 214.0
HFD2_k127_100806_7 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000008565 211.0
HFD2_k127_100806_8 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000002706 177.0
HFD2_k127_100806_9 Serine aminopeptidase, S33 - - - 0.000000000000001604 87.0
HFD2_k127_1051280_0 TIGRFAM FeS assembly protein SufB K07033,K09014 - - 4.938e-228 723.0
HFD2_k127_1051280_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 1.152e-218 689.0
HFD2_k127_1051280_10 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003641 519.0
HFD2_k127_1051280_11 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 495.0
HFD2_k127_1051280_12 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004245 481.0
HFD2_k127_1051280_13 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 466.0
HFD2_k127_1051280_14 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K17722 - 1.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 438.0
HFD2_k127_1051280_15 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005343 412.0
HFD2_k127_1051280_16 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 391.0
HFD2_k127_1051280_17 Lactonase, 7-bladed beta-propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 392.0
HFD2_k127_1051280_18 PFAM ABC transporter related K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005856 360.0
HFD2_k127_1051280_19 PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP K20276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008761 372.0
HFD2_k127_1051280_2 Sodium/hydrogen exchanger family K03455 - - 4.722e-213 686.0
HFD2_k127_1051280_20 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 350.0
HFD2_k127_1051280_21 MatE K03327 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000421 346.0
HFD2_k127_1051280_22 Binding-protein-dependent transport system inner membrane component K15582 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 344.0
HFD2_k127_1051280_23 Sodium:solute symporter family K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004746 334.0
HFD2_k127_1051280_24 Inositol monophosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006793 329.0
HFD2_k127_1051280_25 TonB-dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 343.0
HFD2_k127_1051280_26 Binding-protein-dependent transport system inner membrane component K15581 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 323.0
HFD2_k127_1051280_27 Peptidase family M50 K06212,K06402 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 307.0
HFD2_k127_1051280_28 Uncharacterized protein family (UPF0051) K09015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006081 322.0
HFD2_k127_1051280_29 Phospholipase D. Active site motifs. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 305.0
HFD2_k127_1051280_3 4Fe-4S dicluster domain K17723 - 1.3.1.1 2.598e-202 641.0
HFD2_k127_1051280_30 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008725 268.0
HFD2_k127_1051280_31 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008269 251.0
HFD2_k127_1051280_32 ethanolamine kinase activity K07251 - 2.7.1.89 0.0000000000000000000000000000000000000000000000000000000000000000000001193 258.0
HFD2_k127_1051280_33 Methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000002392 255.0
HFD2_k127_1051280_34 Saccharopine dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000001259 237.0
HFD2_k127_1051280_35 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000965 229.0
HFD2_k127_1051280_36 ubiquinone menaquinone biosynthesis methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000001351 225.0
HFD2_k127_1051280_37 PFAM alanine dehydrogenase PNT domain protein K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000001703 208.0
HFD2_k127_1051280_38 Polysaccharide biosynthesis C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000001826 207.0
HFD2_k127_1051280_39 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000009719 196.0
HFD2_k127_1051280_4 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 3.074e-195 622.0
HFD2_k127_1051280_40 Phosphoesterase family K21302 - 3.1.3.64 0.00000000000000000000000000000000000000000000000002576 194.0
HFD2_k127_1051280_41 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000006192 188.0
HFD2_k127_1051280_42 metallopeptidase activity - - - 0.000000000000000000000000000000000000000000000006742 194.0
HFD2_k127_1051280_43 Rhomboid family - - - 0.000000000000000000000000000000000000000000000007487 183.0
HFD2_k127_1051280_44 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000007187 190.0
HFD2_k127_1051280_45 NADP transhydrogenase K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000001758 173.0
HFD2_k127_1051280_46 PFAM Transcriptional regulator - - - 0.00000000000000000000000000000000000000000001026 179.0
HFD2_k127_1051280_47 SUF system FeS assembly protein, NifU family K04488 - - 0.00000000000000000000000000000000000000000199 159.0
HFD2_k127_1051280_48 OsmC-like protein K04063 - - 0.000000000000000000000000000000000000000003212 159.0
HFD2_k127_1051280_49 CHRD domain - - - 0.0000000000000000000000000000000000000007054 160.0
HFD2_k127_1051280_5 Phosphoesterase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008587 621.0
HFD2_k127_1051280_50 Phosphodiester glycosidase - - - 0.00000000000000000000000000000000000000447 161.0
HFD2_k127_1051280_51 MerR, DNA binding K19591 - - 0.0000000000000000000000000000000000001728 147.0
HFD2_k127_1051280_52 Phospholipid methyltransferase - - - 0.000000000000000000000000000000004037 137.0
HFD2_k127_1051280_53 enzyme binding K00567,K07443 - 2.1.1.63 0.00000000000000000000000000000807 128.0
HFD2_k127_1051280_54 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.0000000000000000000000000269 123.0
HFD2_k127_1051280_55 CAAX protease self-immunity K07052 - - 0.00000000000000000000000004571 121.0
HFD2_k127_1051280_56 PFAM Rieske 2Fe-2S domain protein K00363,K05710 - 1.7.1.15 0.00000000000000000000000009257 124.0
HFD2_k127_1051280_57 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000003102 117.0
HFD2_k127_1051280_58 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.000000000000000000000002759 116.0
HFD2_k127_1051280_59 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000002859 102.0
HFD2_k127_1051280_6 Zinc carboxypeptidase K14054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007153 557.0
HFD2_k127_1051280_60 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000001432 94.0
HFD2_k127_1051280_61 NUDIX domain - - - 0.00000000000002192 86.0
HFD2_k127_1051280_62 Pfam:DUF59 - - - 0.000000000002669 76.0
HFD2_k127_1051280_63 - - - - 0.000000004182 65.0
HFD2_k127_1051280_64 Endonuclease I - - - 0.0000003634 64.0
HFD2_k127_1051280_65 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.0000003706 56.0
HFD2_k127_1051280_66 Belongs to the glycosyl hydrolase 13 family - - - 0.0000005152 61.0
HFD2_k127_1051280_67 Zinc-dependent metalloprotease - - - 0.0000009123 60.0
HFD2_k127_1051280_68 Matrixin - - - 0.000004375 56.0
HFD2_k127_1051280_7 Amidohydrolase family K01464 - 3.5.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004953 535.0
HFD2_k127_1051280_70 Adenylate cyclase - - - 0.00007929 53.0
HFD2_k127_1051280_71 NUDIX domain K03575 - - 0.0003415 49.0
HFD2_k127_1051280_8 Carbon-nitrogen hydrolase K01431,K12251 - 3.5.1.53,3.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 502.0
HFD2_k127_1051280_9 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003241 522.0
HFD2_k127_109795_0 ABC transporter, transmembrane K18889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008213 555.0
HFD2_k127_109795_1 ABC transporter K06147,K18890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 558.0
HFD2_k127_109795_10 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000006273 71.0
HFD2_k127_109795_2 COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming) K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 362.0
HFD2_k127_109795_3 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004896 281.0
HFD2_k127_109795_4 MFS_1 like family - - - 0.0000000000000000000000000000000000000000000000000000246 204.0
HFD2_k127_109795_5 Cro/C1-type HTH DNA-binding domain - - - 0.00000000000000000000000000000000002914 143.0
HFD2_k127_109795_6 Methyltransferase domain - - - 0.000000000000000000000000000006607 138.0
HFD2_k127_109795_7 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000001053 108.0
HFD2_k127_109795_8 - - - - 0.00000000007103 76.0
HFD2_k127_109795_9 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000004882 72.0
HFD2_k127_1148437_0 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006625 469.0
HFD2_k127_1148437_1 DNA-templated transcription, initiation - - - 0.0000000000000000000000000000000000000007055 160.0
HFD2_k127_1148437_2 Yqey-like protein K09117 - - 0.00000000000000000000000000002664 123.0
HFD2_k127_1148437_3 Mo-molybdopterin cofactor metabolic process K03636,K21147 GO:0000096,GO:0000097,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.80,2.8.1.11 0.0000000000000001725 86.0
HFD2_k127_1148437_4 - - - - 0.0000007089 57.0
HFD2_k127_1176136_0 radical SAM domain protein K22226 - - 0.0000000000000000000000000000000000000000000000000000000000000000008152 247.0
HFD2_k127_1198884_0 OPT oligopeptide transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007137 527.0
HFD2_k127_1198884_1 Polysaccharide biosynthesis protein K15856 - 1.1.1.281 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000433 420.0
HFD2_k127_1198884_10 Tetratricopeptide repeat - - - 0.000000000000000005011 98.0
HFD2_k127_1198884_11 polysaccharide biosynthetic process - - - 0.000000178 64.0
HFD2_k127_1198884_2 Catalyzes the conversion of dihydroorotate to orotate with NAD( ) as electron acceptor K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 309.0
HFD2_k127_1198884_3 Domain of unknown function (DUF3473) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001506 255.0
HFD2_k127_1198884_4 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000001343 174.0
HFD2_k127_1198884_5 EamA-like transporter family - - - 0.00000000000000000000000000000000001458 147.0
HFD2_k127_1198884_6 Formyl transferase - - - 0.000000000000000000000000000000000396 150.0
HFD2_k127_1198884_7 glyoxalase III activity - - - 0.0000000000000000000000000001519 122.0
HFD2_k127_1198884_8 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K02823 - - 0.000000000000000000000000001609 131.0
HFD2_k127_1198884_9 PFAM sigma-70 region 2 domain protein K03088 - - 0.00000000000000000000000002334 119.0
HFD2_k127_1230670_0 Tricorn protease homolog K08676 - - 0.0 1437.0
HFD2_k127_1230670_1 Prokaryotic cytochrome b561 - - - 0.0 1146.0
HFD2_k127_1230670_10 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.0000000000000001124 92.0
HFD2_k127_1230670_11 Cytochrome c554 and c-prime - - - 0.0000000000006965 80.0
HFD2_k127_1230670_2 Penicillin amidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 567.0
HFD2_k127_1230670_3 Cytochrome b subunit of formate dehydrogenase-like protein - GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0006790,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016002,GO:0016043,GO:0016491,GO:0016667,GO:0017144,GO:0019748,GO:0020037,GO:0022607,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044272,GO:0044550,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0051259,GO:0051260,GO:0055114,GO:0065003,GO:0070206,GO:0070207,GO:0070813,GO:0070814,GO:0071840,GO:0097159,GO:1901363,GO:1903136 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006545 546.0
HFD2_k127_1230670_4 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 512.0
HFD2_k127_1230670_5 denitrification pathway K02569,K15876 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 394.0
HFD2_k127_1230670_6 Cytochrome c554 and c-prime K03620 - - 0.000000000000000000000000000000000000000000000000000000346 209.0
HFD2_k127_1230670_7 Cytochrome b/b6/petB K00412,K03888 - - 0.00000000000000000000000000000000000000001481 172.0
HFD2_k127_1230670_8 oxidoreductase activity, acting on diphenols and related substances as donors K02636 - 1.10.9.1 0.0000000000000000001546 95.0
HFD2_k127_1230670_9 BlaR1 peptidase M56 - - - 0.000000000000000001625 96.0
HFD2_k127_1253038_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.228e-212 674.0
HFD2_k127_1253038_1 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 492.0
HFD2_k127_1253038_10 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000008865 206.0
HFD2_k127_1253038_11 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000009826 165.0
HFD2_k127_1253038_12 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.000000000000000000000000000000001576 138.0
HFD2_k127_1253038_13 PTS system mannose fructose sorbose family IID component K02796 - - 0.000000000000000000000001899 119.0
HFD2_k127_1253038_14 PTS system sorbose subfamily IIB component K19507 - - 0.00000000000000000000002222 111.0
HFD2_k127_1253038_15 PTS HPr component phosphorylation site K11189 - - 0.00000000000000000006382 102.0
HFD2_k127_1253038_16 regulation of translation K05808 - - 0.000000000007541 71.0
HFD2_k127_1253038_17 Lipopolysaccharide-assembly, LptC-related - - - 0.00000000004933 71.0
HFD2_k127_1253038_18 PTS system mannose fructose sorbose family K02793 - 2.7.1.191 0.00000000005785 75.0
HFD2_k127_1253038_19 PTS system sorbose-specific iic component K02795 - - 0.00004682 55.0
HFD2_k127_1253038_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009118 407.0
HFD2_k127_1253038_20 Tetratricopeptide repeat - - - 0.00007694 53.0
HFD2_k127_1253038_3 RNA polymerase sigma-54 factor K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 368.0
HFD2_k127_1253038_4 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 335.0
HFD2_k127_1253038_5 Arabinose 5-phosphate isomerase K06041 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0019146,GO:0019294,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0046364,GO:0046394,GO:0046400,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 299.0
HFD2_k127_1253038_6 lipopolysaccharide transport protein B ATP-binding component of ABC superfamily K01990,K06861 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001608 295.0
HFD2_k127_1253038_7 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002473 284.0
HFD2_k127_1253038_8 3-deoxy-8-phosphooctulonate synthase activity K01627 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008676,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016043,GO:0016051,GO:0016053,GO:0016740,GO:0016765,GO:0019294,GO:0019752,GO:0022607,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046394,GO:0046400,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004228 289.0
HFD2_k127_1253038_9 Bifunctional phosphoglucose phosphomannose isomerase K15916 - 5.3.1.8,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000006404 230.0
HFD2_k127_1304983_0 Belongs to the ClpA ClpB family K03695,K03696 - - 3.645e-268 840.0
HFD2_k127_1304983_1 Surface antigen K07277 GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 419.0
HFD2_k127_1304983_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004748 320.0
HFD2_k127_1304983_3 Outer membrane protein (OmpH-like) K06142 - - 0.00000000000000000000007825 105.0
HFD2_k127_1304983_4 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02372,K02535,K13599,K16363 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0019171 3.5.1.108,4.2.1.59 0.0000000003228 72.0
HFD2_k127_134070_0 PFAM glycosyl transferase family 35 K00688 - 2.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 629.0
HFD2_k127_134070_1 PFAM Multi antimicrobial extrusion protein MatE K03327 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005961 448.0
HFD2_k127_134070_10 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K00826 - 2.6.1.42 0.000000000000000000000000000000000000000642 160.0
HFD2_k127_134070_11 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000005615 157.0
HFD2_k127_134070_12 Amidohydrolase family - - - 0.0000000000000000000000000000000000001352 156.0
HFD2_k127_134070_13 GGDEF Domain - - - 0.000000000000000000000000000144 124.0
HFD2_k127_134070_14 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K04517 - 1.3.1.12 0.000000000000000000000000001781 126.0
HFD2_k127_134070_15 PFAM AIG2 family protein - - - 0.000000000000000000000000007767 118.0
HFD2_k127_134070_16 Chorismate mutase type I K06208 - 5.4.99.5 0.000000000000000000003118 107.0
HFD2_k127_134070_17 Lamin Tail Domain - - - 0.000000000000000000008467 102.0
HFD2_k127_134070_18 Anthranilate synthase component I, N terminal region K01657,K01665 - 2.6.1.85,4.1.3.27 0.00000000000000001329 87.0
HFD2_k127_134070_19 Acetyltransferase (GNAT) family - - - 0.00000000000002008 79.0
HFD2_k127_134070_2 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008198 326.0
HFD2_k127_134070_20 Protein involved in meta-pathway of phenol degradation - - - 0.00000000000003967 83.0
HFD2_k127_134070_21 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone - - - 0.000000001384 69.0
HFD2_k127_134070_22 polysaccharide catabolic process K01176,K01179 - 3.2.1.1,3.2.1.4 0.00001738 58.0
HFD2_k127_134070_3 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 330.0
HFD2_k127_134070_4 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000425 280.0
HFD2_k127_134070_5 benzoyl-CoA oxygenase K15512 - 1.14.13.208 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005186 287.0
HFD2_k127_134070_6 Prolyl oligopeptidase family K06889,K19188 - 3.7.1.19 0.00000000000000000000000000000000000000000000000000008574 205.0
HFD2_k127_134070_7 Belongs to the peptidase S11 family K01286,K07258,K07262 GO:0000003,GO:0000270,GO:0000910,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0006022,GO:0006508,GO:0006807,GO:0007049,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016043,GO:0016787,GO:0019538,GO:0019954,GO:0022402,GO:0022414,GO:0030203,GO:0032505,GO:0042221,GO:0042493,GO:0042597,GO:0043093,GO:0043170,GO:0044238,GO:0044464,GO:0045229,GO:0050896,GO:0051301,GO:0070011,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0140096,GO:1901135,GO:1901564 3.4.16.4 0.0000000000000000000000000000000000000000000000001418 189.0
HFD2_k127_134070_8 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner - - - 0.0000000000000000000000000000000000000000001771 168.0
HFD2_k127_134070_9 PFAM GlcNAc-PI de-N-acetylase K01463 - - 0.000000000000000000000000000000000000000006121 164.0
HFD2_k127_1385670_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 2.863e-305 944.0
HFD2_k127_1385670_1 DNA topoisomerase II activity K03167 - 5.99.1.3 1.288e-294 918.0
HFD2_k127_1385670_10 Metal dependent phosphohydrolases with conserved 'HD' motif. K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 324.0
HFD2_k127_1385670_11 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003869 287.0
HFD2_k127_1385670_12 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000007503 239.0
HFD2_k127_1385670_13 metallopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000538 206.0
HFD2_k127_1385670_14 Isoprenylcysteine carboxyl methyltransferase K16168 - - 0.00000000000000000000000000000000007572 151.0
HFD2_k127_1385670_15 DNA topoisomerase VI subunit A K03166 - 5.99.1.3 0.0000000000000000000003779 100.0
HFD2_k127_1385670_16 Domain of unknown function (DUF4154) - - - 0.000000000000000000003255 104.0
HFD2_k127_1385670_17 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000006232 104.0
HFD2_k127_1385670_18 PEP-CTERM motif - - - 0.00000000000148 79.0
HFD2_k127_1385670_19 Putative Ig domain - - - 0.00000000003491 76.0
HFD2_k127_1385670_2 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K02564 - 3.5.99.6 3.219e-248 801.0
HFD2_k127_1385670_20 LVIVD repeat K01179 - 3.2.1.4 0.00000002631 65.0
HFD2_k127_1385670_21 Belongs to the glycosyl hydrolase 13 family - - - 0.00000003612 66.0
HFD2_k127_1385670_22 LVIVD repeat K01179 - 3.2.1.4 0.000009888 61.0
HFD2_k127_1385670_3 histidine kinase HAMP region domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008974 605.0
HFD2_k127_1385670_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 628.0
HFD2_k127_1385670_5 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 494.0
HFD2_k127_1385670_6 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 413.0
HFD2_k127_1385670_7 Peptidase, M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 407.0
HFD2_k127_1385670_8 Dimerisation domain of Zinc Transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 353.0
HFD2_k127_1385670_9 Chalcone and stilbene synthases, N-terminal domain K16167 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006794 327.0
HFD2_k127_1429992_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003675 482.0
HFD2_k127_1429992_1 GDSL-like Lipase/Acylhydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002094 249.0
HFD2_k127_1429992_2 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K07083,K11785 - - 0.000000005603 70.0
HFD2_k127_1438226_0 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.00000000000000000000000000000003703 128.0
HFD2_k127_1438226_1 - - - - 0.0000000000000000001864 94.0
HFD2_k127_1491873_0 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 331.0
HFD2_k127_1491873_1 COG0668 Small-conductance mechanosensitive channel K03442 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001206 286.0
HFD2_k127_1491873_2 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00000000000000000000000000000000000000000000000000000000000000009173 254.0
HFD2_k127_1491873_3 - - - - 0.00000000000000000359 92.0
HFD2_k127_1491873_4 Glycine-zipper domain - - - 0.0000000000000006002 87.0
HFD2_k127_1491873_5 Outer membrane protein beta-barrel domain - - - 0.00001291 57.0
HFD2_k127_1511448_0 Catalyzes the specific phosphorylation of arginine residues in proteins K19405 - 2.7.14.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005945 326.0
HFD2_k127_1511448_1 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008728 297.0
HFD2_k127_1511448_2 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.000000000000000000000000000000000000000000000000000000006667 219.0
HFD2_k127_1511448_3 protein with conserved CXXC pairs K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 - 0.00000000000000000000000000000000000000001028 160.0
HFD2_k127_1511448_4 with chaperone activity ATP-binding K03696 - - 0.00000000000000000000000000001883 122.0
HFD2_k127_1522807_0 Hypothetical methyltransferase K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 387.0
HFD2_k127_1522807_1 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 379.0
HFD2_k127_1522807_11 PFAM NUDIX hydrolase K03574 - 3.6.1.55 0.00000000000000000001746 98.0
HFD2_k127_1522807_12 E3 Ubiquitin ligase - - - 0.00000000000007636 85.0
HFD2_k127_1522807_13 inositol 2-dehydrogenase activity K09949 - - 0.00000009765 64.0
HFD2_k127_1522807_2 Major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 310.0
HFD2_k127_1522807_3 Oxidoreductase activity. It is involved in the biological process described with metabolic process - - - 0.0000000000000000000000000000000000000000000000000000000008202 216.0
HFD2_k127_1522807_4 LemA family K03744 - - 0.00000000000000000000000000000000000000000000006817 182.0
HFD2_k127_1522807_5 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000002038 148.0
HFD2_k127_1522807_6 PFAM Squalene phytoene synthase K00801 - 2.5.1.21 0.000000000000000000000000000000000001472 154.0
HFD2_k127_1522807_7 transferase activity, transferring acyl groups K03824 - - 0.00000000000000000000000000000004604 143.0
HFD2_k127_1522807_9 cytochrome oxidase biogenesis protein Cox15-CtaA K02259 - - 0.00000000000000000000004835 104.0
HFD2_k127_1559841_0 Pkd domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008582 531.0
HFD2_k127_1581963_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.055e-211 676.0
HFD2_k127_1581963_1 COG2723 Beta-glucosidase 6-phospho-beta-glucosidase beta- galactosidase K05350 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 535.0
HFD2_k127_1581963_10 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000004644 208.0
HFD2_k127_1581963_11 coagulation factor 5 8 type - - - 0.000000000000000000000000000000000000000000000000000003458 198.0
HFD2_k127_1581963_12 Belongs to the ompA family K03286 - - 0.0000000000000000000000000000000000000008112 166.0
HFD2_k127_1581963_13 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000005813 140.0
HFD2_k127_1581963_14 HNH nucleases - - - 0.000000000000000000000000000000000006708 150.0
HFD2_k127_1581963_15 - - - - 0.000000000000000000000000003056 119.0
HFD2_k127_1581963_16 - - - - 0.00000000000000000000021 107.0
HFD2_k127_1581963_18 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000007869 71.0
HFD2_k127_1581963_2 Endoribonuclease that initiates mRNA decay K18682 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 536.0
HFD2_k127_1581963_20 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000005868 58.0
HFD2_k127_1581963_21 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00003453 51.0
HFD2_k127_1581963_3 6-phosphofructokinase activity K00850,K00895,K21071 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008443,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0046872,GO:0047334,GO:0071704,GO:1901135 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 530.0
HFD2_k127_1581963_4 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 501.0
HFD2_k127_1581963_5 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004331 345.0
HFD2_k127_1581963_6 YmdB-like protein K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002811 324.0
HFD2_k127_1581963_7 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006204 306.0
HFD2_k127_1581963_8 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000001486 269.0
HFD2_k127_1581963_9 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767 - 0.00000000000000000000000000000000000000000000000000000004795 214.0
HFD2_k127_1595883_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 2.84e-204 646.0
HFD2_k127_1595883_1 Belongs to the aspartate glutamate racemases family K01779 - 5.1.1.13 0.000000000000000000000000000000000000000000000000000147 201.0
HFD2_k127_1595883_2 Protein of unknown function (DUF3311) - - - 0.00000000007654 67.0
HFD2_k127_1595883_3 SET domain K07117 - - 0.000000000493 66.0
HFD2_k127_1595883_4 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.00003579 57.0
HFD2_k127_1595883_5 Belongs to the peptidase S8 family K13276,K17734 - - 0.0005722 53.0
HFD2_k127_1644371_0 UDP-glucose 4-epimerase activity K01784,K17947 - 5.1.3.2,5.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000619 338.0
HFD2_k127_1644371_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000265 203.0
HFD2_k127_1644371_2 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.0000000000000000000000000005773 120.0
HFD2_k127_1644371_3 HNH nucleases - - - 0.0000000000000004544 86.0
HFD2_k127_1644371_4 Glycosyl transferases group 1 - - - 0.0003206 53.0
HFD2_k127_1684796_0 Two component, sigma54 specific, transcriptional regulator, Fis family K02667,K07713,K07714,K19641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003825 460.0
HFD2_k127_1684796_1 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003466 287.0
HFD2_k127_1684796_2 ABC transporter, ATP-binding protein K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002444 270.0
HFD2_k127_1684796_3 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000002541 241.0
HFD2_k127_1684796_4 ABC-2 family transporter protein - - - 0.0000000000000000000000001033 119.0
HFD2_k127_1684796_5 Prokaryotic N-terminal methylation motif K02456,K02650 - - 0.00000000003504 70.0
HFD2_k127_1684796_6 Pfam:N_methyl_2 K02650 - - 0.000000006004 69.0
HFD2_k127_1684796_7 peptidyl-tyrosine sulfation - - - 0.000000438 63.0
HFD2_k127_1729365_0 Fibronectin type 3 domain - - - 0.000001713 60.0
HFD2_k127_1774755_0 Glycosyltransferase Family 4 - - - 0.0000000000000000002472 100.0
HFD2_k127_1774755_1 polysaccharide deacetylase - - - 0.00000001112 60.0
HFD2_k127_1774755_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000006826 56.0
HFD2_k127_1795817_0 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000007006 148.0
HFD2_k127_1795817_1 Thiol-disulfide isomerase and - - - 0.0000000000000000000000000004738 128.0
HFD2_k127_1805356_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 481.0
HFD2_k127_1805356_1 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000468 445.0
HFD2_k127_1805356_2 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003289 307.0
HFD2_k127_1805356_3 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009867 252.0
HFD2_k127_1805356_4 Aminoacyl-tRNA editing domain - - - 0.000000000000000000000000000000000000000000002945 186.0
HFD2_k127_1805356_5 MlaD protein K02067 - - 0.00000000000000000000000000000000000000004356 164.0
HFD2_k127_1805356_6 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.0000000000000000000000000000000000000005852 165.0
HFD2_k127_1835715_0 endonuclease activity K07451 - - 0.000000000000000000000000000000000000000000000000003168 197.0
HFD2_k127_1835715_1 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.000000000000000000000003115 104.0
HFD2_k127_1835715_2 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000001437 98.0
HFD2_k127_183988_0 PD-(D/E)XK nuclease superfamily - - - 1.274e-201 657.0
HFD2_k127_183988_1 UvrD/REP helicase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000213 201.0
HFD2_k127_183988_2 WYL domain K13572 - - 0.0000000003346 70.0
HFD2_k127_183988_3 response to nickel cation - - - 0.00001857 51.0
HFD2_k127_1863468_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007414 612.0
HFD2_k127_1863468_1 Fungalysin/Thermolysin Propeptide Motif - - - 0.00000000000005315 86.0
HFD2_k127_1863468_2 PFAM glycosyl transferase family 9 K02843 - - 0.000000007859 57.0
HFD2_k127_1863468_3 heptosyltransferase ii K02843 - - 0.00001142 55.0
HFD2_k127_1882176_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 301.0
HFD2_k127_1882176_1 serine-type endopeptidase activity K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000001175 270.0
HFD2_k127_1882176_2 Homoserine dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001987 248.0
HFD2_k127_1882176_3 Carbon-nitrogen hydrolase K03820 - - 0.000000000000000000000000000000000000000000000000000000000008335 234.0
HFD2_k127_1882176_4 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000007115 175.0
HFD2_k127_1882176_5 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 0.000000812 53.0
HFD2_k127_1936482_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000488 554.0
HFD2_k127_1936482_1 6-phosphogluconate dehydrogenase K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 434.0
HFD2_k127_1936482_2 Ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 325.0
HFD2_k127_1936482_3 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001127 285.0
HFD2_k127_1936482_4 Transcriptional regulator sugar kinase K00886 - 2.7.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000001313 266.0
HFD2_k127_1936482_5 Acyltransferase - - - 0.0000000000000000000000000000000000000000000000005681 193.0
HFD2_k127_1936482_6 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.00000000000000000000000000000000000000000154 168.0
HFD2_k127_1936482_7 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.00000000000000000000000000000000000004892 154.0
HFD2_k127_1936482_9 Outer membrane protein beta-barrel domain K11934 - - 0.000284 51.0
HFD2_k127_1944379_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007174 492.0
HFD2_k127_1944379_1 Protein of unknown function (DUF2723) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004764 363.0
HFD2_k127_1944379_10 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000001416 142.0
HFD2_k127_1944379_11 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000000008615 131.0
HFD2_k127_1944379_12 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000009418 94.0
HFD2_k127_1944379_2 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 353.0
HFD2_k127_1944379_3 NAD dependent epimerase dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006745 338.0
HFD2_k127_1944379_4 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005674 311.0
HFD2_k127_1944379_5 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 310.0
HFD2_k127_1944379_6 riboflavin synthase, alpha K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000003494 210.0
HFD2_k127_1944379_7 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000002008 203.0
HFD2_k127_1944379_8 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000003203 202.0
HFD2_k127_1944379_9 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000001649 161.0
HFD2_k127_1973817_0 Luciferase-like monooxygenase K04091,K17228 - 1.14.14.35,1.14.14.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008809 537.0
HFD2_k127_1973817_1 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 477.0
HFD2_k127_1973817_10 protein serine/threonine phosphatase activity - - - 0.00000000000000000000000000000000000000000000369 172.0
HFD2_k127_1973817_11 RimK-like ATP-grasp domain K05844 - - 0.0000000000000000000000000000005183 134.0
HFD2_k127_1973817_12 cheY-homologous receiver domain - - - 0.0000000000000000000006123 112.0
HFD2_k127_1973817_13 - - - - 0.0000000000000251 87.0
HFD2_k127_1973817_2 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000397 469.0
HFD2_k127_1973817_3 RimK-like ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004086 425.0
HFD2_k127_1973817_4 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004071 425.0
HFD2_k127_1973817_5 DJ-1/PfpI family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004459 388.0
HFD2_k127_1973817_6 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 349.0
HFD2_k127_1973817_7 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003591 322.0
HFD2_k127_1973817_8 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005487 272.0
HFD2_k127_1973817_9 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000007263 228.0
HFD2_k127_1974007_0 Ferrous iron transport protein B K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 476.0
HFD2_k127_1974007_1 - - - - 0.00000000000000000000000000000000000000000000000000000009704 218.0
HFD2_k127_1974007_2 FeoA K04758 - - 0.000000000000000002559 87.0
HFD2_k127_1982179_0 Cupredoxin-like domain K00376 - 1.7.2.4 2.024e-231 745.0
HFD2_k127_1982179_1 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008967 574.0
HFD2_k127_1982179_10 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000002194 216.0
HFD2_k127_1982179_11 sequence-specific DNA binding K03719 - - 0.000000000000000000000000000000000000000000004948 168.0
HFD2_k127_1982179_12 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000001654 158.0
HFD2_k127_1982179_13 lipoprotein involved in nitrous oxide reduction K19342 - - 0.00000000000000000000000000000000001779 147.0
HFD2_k127_1982179_14 Recombination protein O C terminal K03584 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000003178 124.0
HFD2_k127_1982179_15 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K01489,K07042 - 3.5.4.5 0.00000000000000000009252 99.0
HFD2_k127_1982179_16 Carbamoyl-phosphate synthetase large chain domain protein K01968 - 6.4.1.4 0.000000000000000004071 94.0
HFD2_k127_1982179_17 cytochrome C - - - 0.00000000000000003587 94.0
HFD2_k127_1982179_18 COG3420 Nitrous oxidase accessory protein K07218 - - 0.00000000009342 69.0
HFD2_k127_1982179_19 Hemerythrin HHE cation binding domain - - - 0.00002656 54.0
HFD2_k127_1982179_2 Psort location CytoplasmicMembrane, score 10.00 K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006291 480.0
HFD2_k127_1982179_20 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0002261 54.0
HFD2_k127_1982179_3 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003479 499.0
HFD2_k127_1982179_4 Acetyl propionyl-CoA carboxylase alpha subunit K01968 - 6.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007651 456.0
HFD2_k127_1982179_5 glycyl-tRNA aminoacylation K01878,K14164 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016874,GO:0016875,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 410.0
HFD2_k127_1982179_6 7TM receptor with intracellular HD hydrolase K07037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 361.0
HFD2_k127_1982179_7 Phosphate starvation-inducible protein PhoH K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004416 307.0
HFD2_k127_1982179_8 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000005082 265.0
HFD2_k127_1982179_9 enoyl-CoA hydratase K13766 - 4.2.1.18 0.000000000000000000000000000000000000000000000000000000000000001061 228.0
HFD2_k127_2000749_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 5.367e-223 707.0
HFD2_k127_2000749_1 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005998 613.0
HFD2_k127_2000749_10 Acyl-CoA dehydrogenase K18244 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 381.0
HFD2_k127_2000749_11 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 379.0
HFD2_k127_2000749_12 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006584 369.0
HFD2_k127_2000749_13 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000187 293.0
HFD2_k127_2000749_14 ArgK protein K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001239 282.0
HFD2_k127_2000749_15 Integral membrane sensor signal transduction histidine kinase K07709,K13924 - 2.1.1.80,2.7.13.3,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000005841 277.0
HFD2_k127_2000749_16 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000163 255.0
HFD2_k127_2000749_17 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000601 260.0
HFD2_k127_2000749_18 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000002804 242.0
HFD2_k127_2000749_19 PFAM FIST C domain - - - 0.000000000000000000000000000000000000000000000000000000000000001301 233.0
HFD2_k127_2000749_2 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 496.0
HFD2_k127_2000749_20 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000007049 214.0
HFD2_k127_2000749_21 Monogalactosyldiacylglycerol (MGDG) synthase - - - 0.0000000000000000000000000000000000000000000000000000000008957 211.0
HFD2_k127_2000749_22 B12 binding domain K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000008829 199.0
HFD2_k127_2000749_23 cellulose binding K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000006764 187.0
HFD2_k127_2000749_24 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000264 155.0
HFD2_k127_2000749_25 cellulose binding K12132 - 2.7.11.1 0.000000000000000000000000000000001622 150.0
HFD2_k127_2000749_26 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.000000000000000000000000000003132 128.0
HFD2_k127_2000749_27 TonB-dependent Receptor Plug - - - 0.00000000000000000000000000008749 135.0
HFD2_k127_2000749_28 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000009069 121.0
HFD2_k127_2000749_29 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000007893 119.0
HFD2_k127_2000749_3 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 492.0
HFD2_k127_2000749_30 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000003465 109.0
HFD2_k127_2000749_31 NAD(P)H dehydrogenase (quinone) activity - - - 0.000000000000003418 83.0
HFD2_k127_2000749_33 PFAM Protein kinase domain K12132 - 2.7.11.1 0.000000000000003862 91.0
HFD2_k127_2000749_34 Preprotein translocase, YajC subunit K03210 - - 0.00000000000000626 83.0
HFD2_k127_2000749_35 Acetyl propionyl-CoA carboxylase alpha subunit K01968 - 6.4.1.4 0.0000000004868 71.0
HFD2_k127_2000749_36 Pkd domain containing protein K00869,K00938 - 2.7.1.36,2.7.4.2 0.0000003206 63.0
HFD2_k127_2000749_38 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 0.0001431 55.0
HFD2_k127_2000749_39 P pilus assembly Cpx signaling pathway, periplasmic inhibitor zinc-resistance associated protein K06006 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006457,GO:0008150,GO:0009987,GO:0010033,GO:0014070,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0044464,GO:0050896,GO:0051082,GO:0061077,GO:1990507 - 0.0002042 51.0
HFD2_k127_2000749_4 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005566 482.0
HFD2_k127_2000749_5 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 460.0
HFD2_k127_2000749_6 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 445.0
HFD2_k127_2000749_7 Acyl-CoA dehydrogenase, N-terminal domain K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009977 438.0
HFD2_k127_2000749_8 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005256 421.0
HFD2_k127_2000749_9 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 394.0
HFD2_k127_2012814_0 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008043 524.0
HFD2_k127_2012814_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005946 471.0
HFD2_k127_2012814_2 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005982 466.0
HFD2_k127_2012814_3 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 441.0
HFD2_k127_2012814_4 M42 glutamyl aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 404.0
HFD2_k127_2012814_5 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009196 292.0
HFD2_k127_2012814_6 Transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000004241 244.0
HFD2_k127_2012814_7 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.0000000000000000000000000000000000000000000000000003655 188.0
HFD2_k127_2012814_8 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000000000000000309 138.0
HFD2_k127_2015573_0 peptidase S9B dipeptidylpeptidase IV domain protein K01278 - 3.4.14.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004445 592.0
HFD2_k127_2015573_1 Outer membrane protein beta-barrel family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 349.0
HFD2_k127_2015573_2 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000001076 195.0
HFD2_k127_2015573_3 FMN binding - - - 0.00000000000000000000000000000000000000000000000117 190.0
HFD2_k127_2015573_4 Cell wall formation K00075 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0055114,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 1.3.1.98 0.00000000000000000000000000002165 124.0
HFD2_k127_2015573_6 Rdx family K07401 - - 0.0000001493 54.0
HFD2_k127_2077521_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001166 255.0
HFD2_k127_2077521_1 alpha-ribazole phosphatase activity K01834 - 5.4.2.11 0.00000000000000000000000000000004663 136.0
HFD2_k127_2077521_2 Phosphoglycerate mutase family member 5 K15637 GO:0003674,GO:0003824,GO:0004721,GO:0004722,GO:0005096,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006914,GO:0008047,GO:0008150,GO:0008152,GO:0008219,GO:0009056,GO:0009987,GO:0012501,GO:0016020,GO:0016236,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0019867,GO:0030234,GO:0030695,GO:0031090,GO:0031966,GO:0031967,GO:0031968,GO:0031975,GO:0036211,GO:0042578,GO:0043085,GO:0043087,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043547,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044877,GO:0050790,GO:0051336,GO:0051345,GO:0060589,GO:0061919,GO:0065007,GO:0065009,GO:0070265,GO:0070266,GO:0071704,GO:0097300,GO:0098588,GO:0098772,GO:0098805,GO:0140096,GO:1901564 3.1.3.16 0.00000000000000000005406 100.0
HFD2_k127_2077521_3 - - - - 0.00000003163 63.0
HFD2_k127_2104340_0 oligopeptide transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007368 525.0
HFD2_k127_2104340_1 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 401.0
HFD2_k127_2104340_2 Ferredoxin--NADP reductase K21567 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 372.0
HFD2_k127_2104340_3 phosphoribosyltransferase K07100 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007689 325.0
HFD2_k127_2104340_4 PFAM NHL repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000004075 237.0
HFD2_k127_2104340_5 A domain in the BMP inhibitor chordin and in microbial proteins. - - - 0.0000000000000000000000000002836 131.0
HFD2_k127_2104340_6 iron ion binding - - - 0.000000000000000000000000003677 121.0
HFD2_k127_2104340_7 Peptidase family C25 - - - 0.0006801 52.0
HFD2_k127_2107329_0 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 586.0
HFD2_k127_2107329_1 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 484.0
HFD2_k127_2107329_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003586 272.0
HFD2_k127_2107329_3 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000000000000000000000000000000000000000000009023 220.0
HFD2_k127_2107329_4 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000007013 177.0
HFD2_k127_2107329_5 RHS Repeat - - - 0.0000000000000000000000000000000000000000003674 185.0
HFD2_k127_2107329_6 Belongs to the HpcH HpaI aldolase family - - - 0.00000000000000000000000000003828 129.0
HFD2_k127_2141964_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 433.0
HFD2_k127_2141964_1 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003189 276.0
HFD2_k127_2141964_10 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000001856 106.0
HFD2_k127_2141964_11 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000772 98.0
HFD2_k127_2141964_12 ribosomal protein l30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000001128 71.0
HFD2_k127_2141964_13 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000001254 71.0
HFD2_k127_2141964_2 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000000005741 217.0
HFD2_k127_2141964_3 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000001523 211.0
HFD2_k127_2141964_4 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000001103 184.0
HFD2_k127_2141964_5 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000002254 168.0
HFD2_k127_2141964_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000002463 180.0
HFD2_k127_2141964_7 Binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000006096 158.0
HFD2_k127_2141964_8 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000000000000000003898 140.0
HFD2_k127_2141964_9 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000001715 138.0
HFD2_k127_2159345_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.121e-234 734.0
HFD2_k127_2159345_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 335.0
HFD2_k127_2159345_10 cellulose binding - - - 0.0000006686 61.0
HFD2_k127_2159345_11 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.0000264 51.0
HFD2_k127_2159345_12 Protein conserved in bacteria - - - 0.00004496 55.0
HFD2_k127_2159345_2 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000003093 250.0
HFD2_k127_2159345_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000001739 233.0
HFD2_k127_2159345_4 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000049 192.0
HFD2_k127_2159345_5 Protein of unknown function (DUF520) K09767 - - 0.00000000000000000000000000000000000000000000449 170.0
HFD2_k127_2159345_6 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000004595 102.0
HFD2_k127_2159345_7 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000001173 101.0
HFD2_k127_2159345_8 NUDIX domain - - - 0.0000000000000001787 87.0
HFD2_k127_2159345_9 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000005587 87.0
HFD2_k127_2175667_0 General secretory system II protein E domain protein K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 503.0
HFD2_k127_2175667_1 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009607 372.0
HFD2_k127_2175667_10 Type IV pilus assembly protein PilM; K02662 - - 0.00000000000000000007469 102.0
HFD2_k127_2175667_11 Bacterial Ig-like domain (group 1) - - - 0.00000000000002677 86.0
HFD2_k127_2175667_12 cellulase activity - - - 0.000000000001369 80.0
HFD2_k127_2175667_13 - - - - 0.000000000002483 76.0
HFD2_k127_2175667_14 long-chain fatty acid transporting porin activity - - - 0.0000000001553 74.0
HFD2_k127_2175667_15 Belongs to the N-Me-Phe pilin family K02650 - - 0.000000007697 63.0
HFD2_k127_2175667_2 acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003683 335.0
HFD2_k127_2175667_3 Integrase catalytic - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 311.0
HFD2_k127_2175667_4 PFAM TRAP dicarboxylate transporter- DctP subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003276 268.0
HFD2_k127_2175667_5 TRAP transporter T-component - - - 0.000000000000000000000000000000000000000000000000000000000000000000001068 253.0
HFD2_k127_2175667_6 Type II secretion system (T2SS), protein F K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000002199 261.0
HFD2_k127_2175667_7 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000966 201.0
HFD2_k127_2175667_8 Type ii and iii secretion system protein K02453,K02507,K02666 - - 0.000000000000000000000000000000000000000000000000002814 198.0
HFD2_k127_2175667_9 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000009704 178.0
HFD2_k127_219554_0 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006115 572.0
HFD2_k127_219554_1 Cytochrome c K00117 - 1.1.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 360.0
HFD2_k127_219554_2 domain protein - - - 0.0000000000000000000000000000000000004654 155.0
HFD2_k127_219554_3 Peptidase dimerisation domain - - - 0.0000000000000000000002215 113.0
HFD2_k127_2201387_0 Putative zinc-binding metallo-peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 403.0
HFD2_k127_2201387_1 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 317.0
HFD2_k127_2201387_2 protein methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000001346 216.0
HFD2_k127_2201387_3 Protein of unknown function (DUF1428) - - - 0.00000000000000000000000000000000000000002734 164.0
HFD2_k127_2201387_4 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.0000000000000000000008003 100.0
HFD2_k127_2201387_5 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000007797 92.0
HFD2_k127_2201387_6 Integrase core domain - - - 0.00000419 49.0
HFD2_k127_2201387_7 COG0823 Periplasmic component of the Tol biopolymer transport system - - - 0.0002091 54.0
HFD2_k127_2203436_0 Sortilin, neurotensin receptor 3, - - - 0.0 1184.0
HFD2_k127_2203436_1 Fungalysin metallopeptidase (M36) - - - 1.423e-300 961.0
HFD2_k127_2203436_2 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 524.0
HFD2_k127_2203436_3 NeuB family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007812 411.0
HFD2_k127_2203436_4 cellulose binding K00505 - 1.14.18.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 392.0
HFD2_k127_2203436_5 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 380.0
HFD2_k127_2203436_6 amino acid K03294,K13868 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005547 336.0
HFD2_k127_2203436_7 Carboxypeptidase - - - 0.0000000000000000000000000000000000000002073 174.0
HFD2_k127_2203436_8 - - - - 0.00000000000003866 79.0
HFD2_k127_2203436_9 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000005943 64.0
HFD2_k127_2214956_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 359.0
HFD2_k127_2214956_1 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002298 269.0
HFD2_k127_2214956_2 Evidence 5 No homology to any previously reported sequences - - - 0.000000000000000000000000000000000000000000000000000000000004406 227.0
HFD2_k127_2214956_3 - - - - 0.000000000000000000000000000000000000000000000000005946 188.0
HFD2_k127_2214956_4 COG601 ABC-type dipeptide oligopeptide nickel transport systems, permease components Amino acid transport and metabolism Inorganic ion transport and metabolism K02033 - - 0.000000000000000000000000000002019 140.0
HFD2_k127_2214956_5 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.00000000000001239 87.0
HFD2_k127_2214956_6 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000003174 70.0
HFD2_k127_2239505_0 Peptidase S46 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004521 586.0
HFD2_k127_2239505_1 Methyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002863 301.0
HFD2_k127_2239505_2 TAP-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000002724 246.0
HFD2_k127_2239505_3 transcriptional regulator - - - 0.0000000000007089 77.0
HFD2_k127_2271124_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009312 591.0
HFD2_k127_2271124_1 PFAM glycoside hydrolase, family 1 K05350 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009092 395.0
HFD2_k127_2271124_2 NAD dependent epimerase/dehydratase family K05281 - 1.3.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 333.0
HFD2_k127_2271124_3 PFAM Peptidase M16 inactive domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009389 311.0
HFD2_k127_2271124_4 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000004259 248.0
HFD2_k127_2271124_5 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000001938 252.0
HFD2_k127_2271124_6 PIN domain K07064 GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007 - 0.00000000000000009246 89.0
HFD2_k127_2271124_7 Protein of unknown function (DUF1572) - - - 0.00000003987 63.0
HFD2_k127_2285068_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009258 314.0
HFD2_k127_2285068_1 Methyltransferase domain K00588 - 2.1.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 284.0
HFD2_k127_2285068_10 Outer membrane protein beta-barrel domain - - - 0.0000000569 65.0
HFD2_k127_2285068_11 Outer membrane protein beta-barrel domain - - - 0.000002468 57.0
HFD2_k127_2285068_2 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002083 286.0
HFD2_k127_2285068_3 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000009329 198.0
HFD2_k127_2285068_4 Cell envelope-related transcriptional attenuator domain - - - 0.0000000000000000000000000000000000000001191 170.0
HFD2_k127_2285068_5 Peptidase M56 - - - 0.0000000000000000000000009702 118.0
HFD2_k127_2285068_6 COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000000000000000000004218 111.0
HFD2_k127_2285068_7 Predicted membrane protein (DUF2339) - - - 0.0000000000000000009306 102.0
HFD2_k127_2285068_8 Universal stress protein - - - 0.000000000000125 83.0
HFD2_k127_2285068_9 BlaR1 peptidase M56 - - - 0.00000000109 69.0
HFD2_k127_2307199_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 363.0
HFD2_k127_2307199_1 Metallopeptidase family M24 K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000002037 275.0
HFD2_k127_2307199_2 Methyltransferase domain - - - 0.000000000000000000000000000000000000006444 160.0
HFD2_k127_2307199_3 peptidyl-tyrosine sulfation - - - 0.0000007227 62.0
HFD2_k127_2307199_4 COG0457 FOG TPR repeat - - - 0.00001529 58.0
HFD2_k127_2377573_0 thiolester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000004086 220.0
HFD2_k127_2377573_1 ABC 3 transport family K02075 - - 0.000000000000000000000000000000000000000000000000000000005624 220.0
HFD2_k127_2377573_2 Belongs to the bacterial solute-binding protein 9 family K02077 - - 0.000000000000000000000000000000000000000000000000000001339 211.0
HFD2_k127_2377573_3 Uncharacterized conserved protein (DUF2277) - - - 0.0000000000000000000000000000000000002007 142.0
HFD2_k127_2377573_4 DinB superfamily - - - 0.0000000000000000000000000003737 128.0
HFD2_k127_2377573_5 Nucleoside recognition K06373 - - 0.0000000000000000000002126 96.0
HFD2_k127_2377573_6 phosphate-selective porin O and P - - - 0.0000000000000003211 91.0
HFD2_k127_2377573_7 Protein conserved in bacteria K20274 - - 0.00002784 57.0
HFD2_k127_2381104_0 Domain of unknown function (DUF4440) - - - 0.0000000000000000003343 96.0
HFD2_k127_2381104_1 CARDB - - - 0.000000000267 74.0
HFD2_k127_2381104_2 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.000121 55.0
HFD2_k127_2381104_3 PFAM S-layer domain-containing protein - - - 0.000366 53.0
HFD2_k127_2414285_0 Pkd domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005338 308.0
HFD2_k127_2414285_1 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000001132 259.0
HFD2_k127_2442398_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1067.0
HFD2_k127_2442398_1 SNF2 family N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 467.0
HFD2_k127_2442398_2 activity, protein serine threonine kinase activity, protein-tyrosine kinase activity, ATP binding, regulation of transcription, DNA-dependent, protein amino acid phosphorylation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 385.0
HFD2_k127_2442398_3 Evidence 5 No homology to any previously reported sequences - - - 0.00000006439 67.0
HFD2_k127_2442398_4 PEP-CTERM motif - - - 0.0000004836 61.0
HFD2_k127_2458358_0 GlcNAc-PI de-N-acetylase - - - 2.684e-214 684.0
HFD2_k127_2458358_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.000000000000000000000000000000000000000000000000000000000000002824 226.0
HFD2_k127_2465036_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 330.0
HFD2_k127_2465036_1 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 306.0
HFD2_k127_2465036_10 Histidine kinase - - - 0.0000000000000000000000000000000306 145.0
HFD2_k127_2465036_11 Peptidase M23 K21471 - - 0.0000000000000000000000000000001755 144.0
HFD2_k127_2465036_12 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation K09811 - - 0.0000000000000000000002849 107.0
HFD2_k127_2465036_13 TIGRFAM TonB K03832 - - 0.000000000002541 80.0
HFD2_k127_2465036_14 energy transducer activity K00700,K03832 - 2.4.1.18 0.00000002885 64.0
HFD2_k127_2465036_15 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000003685 64.0
HFD2_k127_2465036_16 Right handed beta helix region - - - 0.0003755 54.0
HFD2_k127_2465036_2 Efflux ABC transporter, permease ATP-binding protein K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002828 279.0
HFD2_k127_2465036_3 ABC-2 family transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000002855 236.0
HFD2_k127_2465036_4 PSP1 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000001674 222.0
HFD2_k127_2465036_5 PFAM Stage II sporulation protein E (SpoIIE) K07315 - 3.1.3.3 0.000000000000000000000000000000000000000004589 171.0
HFD2_k127_2465036_6 PPIC-type PPIASE domain K03771 - 5.2.1.8 0.000000000000000000000000000000000000000007157 173.0
HFD2_k127_2465036_7 ABC transporter K02003 - - 0.00000000000000000000000000000000000000007698 160.0
HFD2_k127_2465036_8 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000009343 163.0
HFD2_k127_2465036_9 LytTr DNA-binding domain K02477 - - 0.000000000000000000000000000000003686 150.0
HFD2_k127_2509985_0 Tricorn protease homolog K08676 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000479 344.0
HFD2_k127_2509985_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000001523 228.0
HFD2_k127_2509985_2 lyase activity - - - 0.0000000000000000000000000324 125.0
HFD2_k127_2541866_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005396 471.0
HFD2_k127_2541866_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005393 381.0
HFD2_k127_2541866_2 Transglycosylase SLT domain K08307,K12204 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001581 298.0
HFD2_k127_2541866_3 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000006083 186.0
HFD2_k127_2586054_0 MMPL family K03296 - - 0.0 1184.0
HFD2_k127_2586054_1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 9.165e-223 721.0
HFD2_k127_2586054_10 4Fe-4S single cluster domain K05337 - - 0.0000000004143 63.0
HFD2_k127_2586054_11 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000008861 72.0
HFD2_k127_2586054_2 Peptidase dimerisation domain K01436,K01438,K01439 - 3.5.1.16,3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007435 513.0
HFD2_k127_2586054_3 PFAM thiamine pyrophosphate protein domain protein TPP-binding K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000822 438.0
HFD2_k127_2586054_4 Biotin-lipoyl like K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000005268 248.0
HFD2_k127_2586054_5 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000003109 191.0
HFD2_k127_2586054_6 ACT domain K09707 - - 0.0000000000000000000000000005855 120.0
HFD2_k127_2586054_7 Methanol dehydrogenase K06872 - - 0.000000000000000000000002305 118.0
HFD2_k127_2586054_8 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000001786 110.0
HFD2_k127_2586054_9 nucleotidyltransferase activity - - - 0.0000000000000000008554 96.0
HFD2_k127_2586282_0 Tricorn protease PDZ domain - - - 0.0 1092.0
HFD2_k127_2586282_1 stress-induced mitochondrial fusion - - - 1.144e-294 917.0
HFD2_k127_2586282_10 Belongs to the peptidase S8 family - - - 0.000001693 62.0
HFD2_k127_2586282_2 COG0457 FOG TPR repeat - - - 6.868e-213 676.0
HFD2_k127_2586282_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 1.024e-202 663.0
HFD2_k127_2586282_4 Ferric reductase like transmembrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006185 361.0
HFD2_k127_2586282_5 Transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006169 347.0
HFD2_k127_2586282_6 peptide catabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007076 374.0
HFD2_k127_2586282_7 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000001213 190.0
HFD2_k127_2586282_8 Protease prsW family - - - 0.0000000000000000000007563 110.0
HFD2_k127_2586282_9 Protein involved in meta-pathway of phenol degradation - - - 0.00000001903 66.0
HFD2_k127_261194_0 Sortilin, neurotensin receptor 3, - - - 6.339e-251 791.0
HFD2_k127_261194_1 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000000000000000000000000000000004557 215.0
HFD2_k127_261194_2 membrane - - - 0.0001063 54.0
HFD2_k127_2635495_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007151 579.0
HFD2_k127_2635495_1 COG1192 ATPases involved in chromosome partitioning K03496 GO:0008150,GO:0022603,GO:0042173,GO:0042174,GO:0043937,GO:0043939,GO:0045595,GO:0045596,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0065007 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008195 332.0
HFD2_k127_2635495_2 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007091 267.0
HFD2_k127_2635495_3 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000001907 250.0
HFD2_k127_2635495_4 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000002081 236.0
HFD2_k127_2635495_5 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.00000000000000000000000000000000000000000000009684 175.0
HFD2_k127_2635495_6 EamA-like transporter family - - - 0.0000000000000000000000001756 117.0
HFD2_k127_2635495_7 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.000000000000002438 87.0
HFD2_k127_2635495_8 Polymer-forming cytoskeletal - - - 0.0000000000001051 77.0
HFD2_k127_2635495_9 Transposase IS200 like - - - 0.0002185 50.0
HFD2_k127_2654539_0 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000005615 241.0
HFD2_k127_2654539_1 PFAM Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000000000000000000000000000000000000000000000000000004192 198.0
HFD2_k127_2733990_0 Conserved repeat domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001211 266.0
HFD2_k127_2774588_0 GTP-binding protein TypA K06207 - - 3.323e-264 829.0
HFD2_k127_2774588_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 526.0
HFD2_k127_2774588_10 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000397 209.0
HFD2_k127_2774588_11 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000000000000000006075 203.0
HFD2_k127_2774588_12 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000006801 191.0
HFD2_k127_2774588_13 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000002488 196.0
HFD2_k127_2774588_14 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000006612 187.0
HFD2_k127_2774588_15 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000001259 203.0
HFD2_k127_2774588_16 Glycosyl hydrolase-like 10 - - - 0.00000000000000000000000000000000000000000000007487 189.0
HFD2_k127_2774588_17 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000000000000000000000000000004697 170.0
HFD2_k127_2774588_18 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000007408 168.0
HFD2_k127_2774588_19 Forms part of the polypeptide exit tunnel K02926,K16193 GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003700,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008428,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030234,GO:0030312,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032069,GO:0032074,GO:0032268,GO:0032269,GO:0032991,GO:0032993,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0065003,GO:0065007,GO:0065009,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0098772,GO:0140110,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000001387 160.0
HFD2_k127_2774588_2 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 497.0
HFD2_k127_2774588_20 Involved in the binding of tRNA to the ribosomes K02946 GO:0001072,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0015935,GO:0019219,GO:0019222,GO:0019538,GO:0022626,GO:0022627,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0140110,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000006756 149.0
HFD2_k127_2774588_21 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000008543 143.0
HFD2_k127_2774588_22 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000002292 145.0
HFD2_k127_2774588_23 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000464 137.0
HFD2_k127_2774588_24 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.000000000000000000000000000000004358 132.0
HFD2_k127_2774588_25 PFAM ribosomal protein L17 K02879 - - 0.00000000000000000000000000000007868 132.0
HFD2_k127_2774588_26 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000009766 117.0
HFD2_k127_2774588_27 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000008031 124.0
HFD2_k127_2774588_28 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000000003061 117.0
HFD2_k127_2774588_29 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000001142 104.0
HFD2_k127_2774588_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 384.0
HFD2_k127_2774588_30 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000001455 104.0
HFD2_k127_2774588_31 PFAM ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000001223 76.0
HFD2_k127_2774588_32 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.0000000008608 67.0
HFD2_k127_2774588_33 Belongs to the bacterial ribosomal protein bL36 family K02919 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000001409 69.0
HFD2_k127_2774588_4 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000581 379.0
HFD2_k127_2774588_5 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0000028,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002532 278.0
HFD2_k127_2774588_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003124 260.0
HFD2_k127_2774588_7 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000000000000000000000011 250.0
HFD2_k127_2774588_8 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000001511 241.0
HFD2_k127_2774588_9 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.0000000000000000000000000000000000000000000000000000000000000005804 223.0
HFD2_k127_2778453_0 Amidohydrolase family - - - 0.0 1343.0
HFD2_k127_2778453_1 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1187.0
HFD2_k127_2778453_10 protein possibly involved in aromatic compounds catabolism - - - 0.000000000000000000000000000000000000000000003554 168.0
HFD2_k127_2778453_11 Glyoxalase-like domain - - - 0.00000000000000000000000000005428 127.0
HFD2_k127_2778453_12 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704,K20453 - 4.2.1.33,4.2.1.35,4.2.1.85 0.00000000000002173 87.0
HFD2_k127_2778453_13 extracellular matrix structural constituent - - - 0.00000000000003985 87.0
HFD2_k127_2778453_15 Cell wall-active antibiotics response 4TMS YvqF - - - 0.00000001356 61.0
HFD2_k127_2778453_2 TonB dependent receptor K02014 - - 1.395e-205 672.0
HFD2_k127_2778453_3 Multicopper oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004606 572.0
HFD2_k127_2778453_4 Amidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009984 467.0
HFD2_k127_2778453_5 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007543 313.0
HFD2_k127_2778453_6 LytTr DNA-binding domain K02477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008442 286.0
HFD2_k127_2778453_7 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000273 255.0
HFD2_k127_2778453_8 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703,K20452 - 4.2.1.33,4.2.1.35,4.2.1.85 0.000000000000000000000000000000000000000000000000000000000000000004279 250.0
HFD2_k127_2778453_9 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000000000000000000000000000000000000009451 225.0
HFD2_k127_2836421_0 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 8.258e-227 714.0
HFD2_k127_2836421_1 amino acid transport K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 426.0
HFD2_k127_2836421_2 phosphate transporter K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 401.0
HFD2_k127_2836421_3 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 364.0
HFD2_k127_2836421_4 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000007782 221.0
HFD2_k127_2836421_5 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000003624 238.0
HFD2_k127_2836421_6 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000003829 168.0
HFD2_k127_2836421_7 Aspartyl protease - - - 0.00000000000000000000000000000002989 145.0
HFD2_k127_2836421_8 Protein of unknown function DUF47 K02039,K07220 GO:0000287,GO:0001558,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006873,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009628,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010563,GO:0010605,GO:0010629,GO:0010966,GO:0016020,GO:0016036,GO:0019220,GO:0019222,GO:0019725,GO:0019897,GO:0019898,GO:0022898,GO:0030002,GO:0030145,GO:0030320,GO:0030643,GO:0031323,GO:0031324,GO:0031667,GO:0031668,GO:0031669,GO:0032409,GO:0032410,GO:0032412,GO:0032413,GO:0032879,GO:0033554,GO:0034605,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0040008,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043269,GO:0043271,GO:0044070,GO:0044092,GO:0044419,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045936,GO:0046677,GO:0046872,GO:0046914,GO:0046983,GO:0048519,GO:0048523,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051174,GO:0051704,GO:0051716,GO:0055062,GO:0055081,GO:0055082,GO:0055083,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071496,GO:0071944,GO:0072501,GO:0072502,GO:0072505,GO:0072506,GO:0098771,GO:0104004,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.000000000000000000000000327 108.0
HFD2_k127_2836421_9 Outer membrane protein beta-barrel domain - - - 0.00001941 55.0
HFD2_k127_2887533_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 8.833e-204 660.0
HFD2_k127_2887533_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004183 542.0
HFD2_k127_2887533_10 MOSC domain - - - 0.0000000000000000000000000000000000000000008086 168.0
HFD2_k127_2887533_11 Alpha beta hydrolase K01048 - 3.1.1.5 0.00000000000000000000000000000000000000236 158.0
HFD2_k127_2887533_12 EVE domain - - - 0.00000000000000000000000000000000005256 138.0
HFD2_k127_2887533_13 Sigma-70 region 2 - - - 0.0000000000000000000007803 111.0
HFD2_k127_2887533_14 - - - - 0.000000000000000001014 101.0
HFD2_k127_2887533_15 CHAT domain - - - 0.000000000000009573 88.0
HFD2_k127_2887533_16 antibiotic catabolic process K13277 - - 0.0000000001423 74.0
HFD2_k127_2887533_17 Protein of unknown function, DUF547 - - - 0.000004124 58.0
HFD2_k127_2887533_2 DNA polymerase K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004444 537.0
HFD2_k127_2887533_3 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008457 373.0
HFD2_k127_2887533_4 PFAM NAD dependent epimerase dehydratase family K01710,K01784 - 4.2.1.46,5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 360.0
HFD2_k127_2887533_5 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003572 274.0
HFD2_k127_2887533_6 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000001702 253.0
HFD2_k127_2887533_7 Proline dehydrogenase K00318 GO:0000166,GO:0003674,GO:0003824,GO:0004657,GO:0005488,GO:0006082,GO:0006520,GO:0006560,GO:0006562,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016491,GO:0016645,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 - 0.00000000000000000000000000000000000000000000000000000000000000001999 234.0
HFD2_k127_2887533_8 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000007202 214.0
HFD2_k127_2887533_9 SMART Integrin alpha beta-propellor repeat protein - - - 0.00000000000000000000000000000000000000000000378 184.0
HFD2_k127_2890324_0 PFAM GlcNAc-PI de-N-acetylase - - - 9.069e-231 743.0
HFD2_k127_2890324_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 516.0
HFD2_k127_2890324_2 serine protease - - - 0.000000000000000000000000000000000000000000000000000000000000000146 239.0
HFD2_k127_2890324_3 Protein of unknown function (DUF2911) - - - 0.000000000000000000000000000000000000000009306 171.0
HFD2_k127_2890324_4 Fha domain - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006110,GO:0006140,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010563,GO:0010675,GO:0010677,GO:0016020,GO:0016310,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0030312,GO:0030808,GO:0030809,GO:0030811,GO:0030812,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0031330,GO:0036211,GO:0042325,GO:0042326,GO:0042802,GO:0043170,GO:0043412,GO:0043457,GO:0043467,GO:0043470,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045820,GO:0045912,GO:0045934,GO:0045936,GO:0045980,GO:0046777,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051174,GO:0051193,GO:0051195,GO:0051196,GO:0051198,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1900371,GO:1900372,GO:1900542,GO:1900543,GO:1901564,GO:1903578,GO:1903579,GO:2001169,GO:2001170 - 0.0000000000009603 79.0
HFD2_k127_2897971_0 Protein involved in outer membrane biogenesis - - - 0.000000000000000000000003961 118.0
HFD2_k127_2897971_1 Uncharacterized protein conserved in bacteria (DUF2062) - - - 0.00000000000000000005136 94.0
HFD2_k127_2899158_0 Beta-L-arabinofuranosidase, GH127 K09955 - - 0.0000000000000000000000000000000000000009368 152.0
HFD2_k127_2899158_1 VanZ like family - - - 0.00005386 55.0
HFD2_k127_2904487_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008233 335.0
HFD2_k127_2904487_1 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009633 290.0
HFD2_k127_2904487_2 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001106 300.0
HFD2_k127_2904487_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000000000004005 184.0
HFD2_k127_2904487_4 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000000000000001835 173.0
HFD2_k127_2904487_5 Metallo-beta-lactamase superfamily - - - 0.0000000000000631 80.0
HFD2_k127_2922038_1 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008012 384.0
HFD2_k127_2922038_2 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000001642 244.0
HFD2_k127_2922038_3 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.0000000000000000000000000000000000000000000000000000000000008155 228.0
HFD2_k127_2952750_0 Cation transporter/ATPase, N-terminus K01531,K12955 - 3.6.3.2 0.0 1053.0
HFD2_k127_2952750_1 ADP binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 494.0
HFD2_k127_2952750_10 3-demethylubiquinone-9 3-O-methyltransferase activity K03428 - 2.1.1.11 0.00000000000000000000000000002523 126.0
HFD2_k127_2952750_11 amine dehydrogenase activity K20276 - - 0.00000000000009854 87.0
HFD2_k127_2952750_13 Kelch motif - GO:0000133,GO:0000278,GO:0000281,GO:0000910,GO:0000935,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0005874,GO:0005875,GO:0005881,GO:0005938,GO:0007049,GO:0007163,GO:0008104,GO:0008150,GO:0008360,GO:0009987,GO:0010639,GO:0015630,GO:0022402,GO:0022603,GO:0022604,GO:0030427,GO:0030428,GO:0031110,GO:0031111,GO:0031113,GO:0031115,GO:0031333,GO:0031500,GO:0032153,GO:0032155,GO:0032187,GO:0032271,GO:0032272,GO:0032506,GO:0032878,GO:0032886,GO:0032991,GO:0033036,GO:0033043,GO:0034613,GO:0035371,GO:0035838,GO:0035839,GO:0035840,GO:0036214,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043254,GO:0044087,GO:0044422,GO:0044424,GO:0044430,GO:0044444,GO:0044446,GO:0044448,GO:0044464,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051129,GO:0051179,GO:0051285,GO:0051286,GO:0051301,GO:0051493,GO:0051494,GO:0051641,GO:0061160,GO:0061172,GO:0061245,GO:0061246,GO:0061640,GO:0065007,GO:0065008,GO:0070507,GO:0070727,GO:0071944,GO:0071963,GO:0072697,GO:0097427,GO:0099070,GO:0099080,GO:0099081,GO:0099512,GO:0099513,GO:0099568,GO:0099738,GO:1902405,GO:1902410,GO:1902486,GO:1902903,GO:1902904,GO:1903047,GO:1904511,GO:1904758,GO:1990151,GO:1990752,GO:1990778,GO:1990896,GO:2000099,GO:2000100,GO:2000114,GO:2000769,GO:2000771 - 0.00000000002521 78.0
HFD2_k127_2952750_14 cellulose binding - - - 0.000000002567 72.0
HFD2_k127_2952750_15 domain protein K01179,K12567,K20276,K21449 - 2.7.11.1,3.2.1.4 0.000000003379 72.0
HFD2_k127_2952750_2 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 406.0
HFD2_k127_2952750_3 protein kinase activity K01972,K02342,K04096 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 2.7.7.7,6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 345.0
HFD2_k127_2952750_4 molybdenum ion binding K07140 - - 0.000000000000000000000000000000000000000000000000000000000000076 224.0
HFD2_k127_2952750_5 - - - - 0.0000000000000000000000000000000000000000000000000000006294 213.0
HFD2_k127_2952750_6 DNA-templated transcription, initiation - - - 0.0000000000000000000000000000000000000000000000004017 189.0
HFD2_k127_2952750_7 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000000000000000004497 173.0
HFD2_k127_2952750_8 Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - 0.0000000000000000000000000000000003731 154.0
HFD2_k127_2952750_9 - - - - 0.00000000000000000000000000000001903 131.0
HFD2_k127_2970519_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002567 273.0
HFD2_k127_2970519_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000015 266.0
HFD2_k127_2970519_2 COG0616 Periplasmic serine proteases (ClpP class) K04773 - - 0.0000000000000000000000000000000000000000000000000000000000008263 240.0
HFD2_k127_2970519_3 Surface antigen - - - 0.0000001512 65.0
HFD2_k127_2970519_4 Tetratricopeptide repeat - - - 0.00007461 51.0
HFD2_k127_2970519_5 cell adhesion involved in biofilm formation - - - 0.0008219 51.0
HFD2_k127_2978069_0 cellulose binding - - - 3.215e-245 794.0
HFD2_k127_2978069_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000048 464.0
HFD2_k127_2978069_2 Surface antigen K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001576 289.0
HFD2_k127_2978069_3 Surface antigen - - - 0.00000000000000000000000000000000000000000000000000000000000002377 234.0
HFD2_k127_2978069_4 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00000000000000000000000000000000000006462 153.0
HFD2_k127_2978069_5 PFAM OmpA MotB domain protein K02557 - - 0.00000000000000000000000000000000471 139.0
HFD2_k127_2978069_6 Biotin-lipoyl like K02005 - - 0.0000000003799 67.0
HFD2_k127_2978069_7 Uncharacterized protein conserved in bacteria (DUF2219) - - - 0.0000008248 61.0
HFD2_k127_298710_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1302.0
HFD2_k127_298710_1 Domain in cystathionine beta-synthase and other proteins. K01697 - 4.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003134 481.0
HFD2_k127_298710_10 nucleotide catabolic process - - - 0.000000000000000000000000000004639 135.0
HFD2_k127_298710_11 DinB family - - - 0.000000000000000002419 95.0
HFD2_k127_298710_12 - - - - 0.000000000000003084 91.0
HFD2_k127_298710_13 Outer membrane efflux protein - - - 0.000000000002956 79.0
HFD2_k127_298710_15 metal cluster binding K19302 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.1.27 0.0000006806 59.0
HFD2_k127_298710_2 Cys Met metabolism K01739,K01758 - 2.5.1.48,4.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004666 487.0
HFD2_k127_298710_3 Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 469.0
HFD2_k127_298710_4 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006942 372.0
HFD2_k127_298710_5 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003651 323.0
HFD2_k127_298710_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001846 302.0
HFD2_k127_298710_7 Heavy-metal-associated domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000002928 252.0
HFD2_k127_298710_8 nucleotide catabolic process - - - 0.00000000000000000000000000000002307 141.0
HFD2_k127_298710_9 Tetratricopeptide repeat - - - 0.0000000000000000000000000000007548 135.0
HFD2_k127_2995403_0 regulator of chromosome condensation, RCC1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000508 310.0
HFD2_k127_2995403_1 FlgD Ig-like domain K21449 - - 0.000000000000000000000000000000000006066 158.0
HFD2_k127_3025557_0 Dehydrogenase E1 component K00164 - 1.2.4.2 1.732e-273 871.0
HFD2_k127_3025557_1 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004373 625.0
HFD2_k127_3025557_10 Prokaryotic N-terminal methylation motif K02458,K02671 - - 0.0001253 54.0
HFD2_k127_3025557_11 COG4970 Tfp pilus assembly protein FimT K08084 - - 0.0004079 51.0
HFD2_k127_3025557_2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 GO:0000166,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009507,GO:0009536,GO:0010035,GO:0010038,GO:0016020,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0017076,GO:0019866,GO:0030554,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045271,GO:0046686,GO:0046872,GO:0046914,GO:0048046,GO:0050896,GO:0050897,GO:0055114,GO:0070469,GO:0097159,GO:0097367,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005228 514.0
HFD2_k127_3025557_3 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005986 406.0
HFD2_k127_3025557_4 Carbohydrate ABC transporter ATP-binding protein, CUT1 family K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000772 359.0
HFD2_k127_3025557_5 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004617 285.0
HFD2_k127_3025557_6 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000001834 207.0
HFD2_k127_3025557_7 Tellurite resistance protein TehB - - - 0.000000000000000000000000000000002928 141.0
HFD2_k127_3025557_8 pilus assembly protein PilW K02672 - - 0.0000000113 67.0
HFD2_k127_3025557_9 type II secretion system protein K - - - 0.00002309 55.0
HFD2_k127_3041560_0 L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp K01876 - 6.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 593.0
HFD2_k127_3041560_1 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 557.0
HFD2_k127_3041560_10 NYN domain - - - 0.00000000000000000008793 102.0
HFD2_k127_3041560_11 methyltransferase - - - 0.000000000009187 75.0
HFD2_k127_3041560_12 - - - - 0.0000000001515 71.0
HFD2_k127_3041560_13 Putative adhesin - - - 0.0000000005609 73.0
HFD2_k127_3041560_14 exo-alpha-(2->6)-sialidase activity K01186 GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509 3.2.1.18 0.0001935 54.0
HFD2_k127_3041560_15 Right handed beta helix region K01186 - 3.2.1.18 0.0003687 54.0
HFD2_k127_3041560_16 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0006397 53.0
HFD2_k127_3041560_2 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009005 507.0
HFD2_k127_3041560_3 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000042 502.0
HFD2_k127_3041560_4 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 434.0
HFD2_k127_3041560_5 PFAM ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007215 359.0
HFD2_k127_3041560_6 Putative adhesin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007528 252.0
HFD2_k127_3041560_7 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000003373 175.0
HFD2_k127_3041560_8 photosynthesis - - - 0.00000000000000000000000000000000000000000001042 186.0
HFD2_k127_3041560_9 Putative Flp pilus-assembly TadE/G-like - - - 0.000000000000000000000000000000000000000007681 178.0
HFD2_k127_3085021_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003326 421.0
HFD2_k127_3085021_1 Belongs to the CarA family K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004751 414.0
HFD2_k127_3085021_2 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 305.0
HFD2_k127_3122901_0 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 408.0
HFD2_k127_3122901_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 399.0
HFD2_k127_3122901_2 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007279 298.0
HFD2_k127_3122901_3 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000005843 211.0
HFD2_k127_3122901_4 S-layer homology domain - - - 0.000000000000002625 90.0
HFD2_k127_3158428_0 electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 7.445e-194 621.0
HFD2_k127_3158428_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03671 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009465 410.0
HFD2_k127_3158428_10 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K21142 - 2.8.1.12 0.000003051 55.0
HFD2_k127_3158428_2 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 373.0
HFD2_k127_3158428_3 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 296.0
HFD2_k127_3158428_4 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000181 298.0
HFD2_k127_3158428_5 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000000001279 223.0
HFD2_k127_3158428_6 MoaE protein K21142 - 2.8.1.12 0.0000000000000000000000000000000003082 139.0
HFD2_k127_3158428_7 domain protein - - - 0.0000000000000000000000000005419 125.0
HFD2_k127_3158428_8 ABC transporter K02003 - - 0.000000000000000000000000001264 112.0
HFD2_k127_3158428_9 regulation of DNA-templated transcription, elongation - - - 0.00000000000000000000001265 115.0
HFD2_k127_3276801_0 SMART Tetratricopeptide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000413 421.0
HFD2_k127_3276801_1 Glycosyl hydrolases family 2, TIM barrel domain K01195 - 3.2.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006211 405.0
HFD2_k127_3276801_10 methylglyoxal synthase activity K01734 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576 4.2.3.3 0.00000000000000000000000000000000000000000000000000000007812 213.0
HFD2_k127_3276801_11 Peptidase M56 - - - 0.00000000000000000000000000000000000000000000000002714 203.0
HFD2_k127_3276801_12 Penicillinase repressor - - - 0.00000000000000000000000000000000000000000002614 165.0
HFD2_k127_3276801_13 Cytochrome c - - - 0.00000000000000000000000000000000000005015 159.0
HFD2_k127_3276801_14 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000002637 143.0
HFD2_k127_3276801_15 - - - - 0.0000000000000000000000006851 119.0
HFD2_k127_3276801_16 - - - - 0.0001408 52.0
HFD2_k127_3276801_2 Permease for cytosine/purines, uracil, thiamine, allantoin K03457 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003771 353.0
HFD2_k127_3276801_3 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 338.0
HFD2_k127_3276801_4 BlaR1 peptidase M56 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 352.0
HFD2_k127_3276801_5 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 302.0
HFD2_k127_3276801_6 Di-haem oxidoreductase, putative peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004553 311.0
HFD2_k127_3276801_7 PFAM Permease for cytosine purines, uracil, thiamine, allantoin K03457 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005261 251.0
HFD2_k127_3276801_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000004155 234.0
HFD2_k127_3276801_9 3-demethylubiquinone-9 3-methyltransferase K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000002489 210.0
HFD2_k127_330880_0 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000002295 222.0
HFD2_k127_3370755_0 iron-nicotianamine transmembrane transporter activity - - - 2.133e-296 928.0
HFD2_k127_3370755_1 Tetratricopeptide repeat - - - 0.000000000000000000000000475 122.0
HFD2_k127_3370755_2 - - - - 0.000000000000000000001639 100.0
HFD2_k127_3395615_0 4Fe-4S dicluster domain K00184 - - 6.474e-233 759.0
HFD2_k127_3395615_1 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 8.057e-218 694.0
HFD2_k127_3395615_10 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000000000000928 143.0
HFD2_k127_3395615_11 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000198 89.0
HFD2_k127_3395615_12 Allergen V5 Tpx-1 family protein - - - 0.00000000000277 72.0
HFD2_k127_3395615_2 Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009085 481.0
HFD2_k127_3395615_3 UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006768 486.0
HFD2_k127_3395615_4 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 330.0
HFD2_k127_3395615_5 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000017 210.0
HFD2_k127_3395615_6 Pfam Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000001309 198.0
HFD2_k127_3395615_7 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000124 171.0
HFD2_k127_3395615_8 oligopeptide transport K03305 - - 0.000000000000000000000000000000000000000000882 162.0
HFD2_k127_3395615_9 Pkd domain containing protein - - - 0.0000000000000000000000000000000001838 151.0
HFD2_k127_3466452_0 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 506.0
HFD2_k127_3466452_1 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004507 428.0
HFD2_k127_3466452_2 Glycosyl transferase family 2 K00721,K00786 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000002093 220.0
HFD2_k127_3466452_3 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000000000000000000000003229 178.0
HFD2_k127_3466452_4 Psort location CytoplasmicMembrane, score K09153 - - 0.0000000000004161 74.0
HFD2_k127_3466452_5 Polysaccharide biosynthesis protein K03328 - - 0.000000000367 73.0
HFD2_k127_3466452_6 PFAM Glycosyl transferase, group 1 - - - 0.00000005193 63.0
HFD2_k127_3466452_7 Polysaccharide biosynthesis protein - - - 0.0002968 52.0
HFD2_k127_3520926_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000003784 183.0
HFD2_k127_3520926_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000005606 181.0
HFD2_k127_3520926_2 Putative bacterial lipoprotein (DUF799) - - - 0.000000001991 69.0
HFD2_k127_3520926_3 Serine threonine protein kinase K12132 - 2.7.11.1 0.000001955 60.0
HFD2_k127_3520926_4 - - - - 0.000002083 59.0
HFD2_k127_3520926_5 Peptidoglycan-synthase activator LpoB - - - 0.000009589 58.0
HFD2_k127_3523244_0 Conserved repeat domain - - - 7.853e-266 891.0
HFD2_k127_3523244_1 Right handed beta helix region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004095 632.0
HFD2_k127_3523244_10 Regulates arginine biosynthesis genes K03402 - - 0.0000000000000000000006985 104.0
HFD2_k127_3523244_11 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000004558 87.0
HFD2_k127_3523244_12 cellulose binding K00505 - 1.14.18.1 0.00000000116 70.0
HFD2_k127_3523244_2 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003433 483.0
HFD2_k127_3523244_3 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 305.0
HFD2_k127_3523244_4 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 GO:0000166,GO:0003674,GO:0005488,GO:0008150,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0048037,GO:0050661,GO:0050662,GO:0070401,GO:0097159,GO:1901265,GO:1901363 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000001516 245.0
HFD2_k127_3523244_5 regulation of response to stimulus K01347,K20276 - 3.4.21.72 0.000000000000000000000000000000000000000000000000152 204.0
HFD2_k127_3523244_6 Argininosuccinate lyase C-terminal K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.000000000000000000000000000000000000000000000009083 190.0
HFD2_k127_3523244_7 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000002075 164.0
HFD2_k127_3523244_8 acid phosphatase activity - - - 0.0000000000000000000000000000003745 143.0
HFD2_k127_3523244_9 TIGRFAM conserved repeat domain - - - 0.0000000000000000000000000003061 117.0
HFD2_k127_3540366_0 Glycosyltransferase 36 associated - - - 2.072e-281 887.0
HFD2_k127_3540366_1 Putative glucoamylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004834 548.0
HFD2_k127_3540366_2 ABC transporter substrate-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009042 432.0
HFD2_k127_3540366_3 Transcriptional regulator K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 315.0
HFD2_k127_3541793_0 PFAM Sulfatase K01130 - 3.1.6.1 0.0 1075.0
HFD2_k127_3541793_1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K09461 - 1.14.13.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003609 567.0
HFD2_k127_3541793_2 COG0076 Glutamate decarboxylase and related PLP-dependent K01593 - 4.1.1.105,4.1.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 527.0
HFD2_k127_3541793_3 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K01556 - 3.7.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005353 471.0
HFD2_k127_3541793_4 tryptophan 2,3-dioxygenase activity K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009114 341.0
HFD2_k127_3541793_5 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003195 265.0
HFD2_k127_3545253_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 510.0
HFD2_k127_3545253_1 ABC transporter K02056 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009433 479.0
HFD2_k127_3545253_10 thymidine kinase activity K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000002105 241.0
HFD2_k127_3545253_11 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.000000000000000000000000000000000000000000000000000000002945 222.0
HFD2_k127_3545253_12 - - - - 0.000000000000000000000000000000000000000000000000000000468 216.0
HFD2_k127_3545253_13 galactose-6-phosphate isomerase activity K00761,K01808 - 2.4.2.9,5.3.1.6 0.000000000000000000000000000000000000000001175 162.0
HFD2_k127_3545253_14 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000003689 156.0
HFD2_k127_3545253_15 Tetratricopeptide repeat protein - - - 0.0000000000000000000000000000000005788 152.0
HFD2_k127_3545253_16 quinone binding - - - 0.0000000000000000000000001553 120.0
HFD2_k127_3545253_17 PFAM transcriptional coactivator pterin dehydratase K01724 - 4.2.1.96 0.000000000000000000002302 107.0
HFD2_k127_3545253_18 Metallo-beta-lactamase superfamily - - - 0.0000000000000008063 91.0
HFD2_k127_3545253_19 Insulinase (Peptidase family M16) - - - 0.0000000000006185 82.0
HFD2_k127_3545253_2 adenosine deaminase K01488 - 3.5.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 403.0
HFD2_k127_3545253_20 DnaJ molecular chaperone homology domain - - - 0.0003359 49.0
HFD2_k127_3545253_3 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 375.0
HFD2_k127_3545253_4 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005192 317.0
HFD2_k127_3545253_5 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006437 319.0
HFD2_k127_3545253_6 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003353 306.0
HFD2_k127_3545253_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007019 288.0
HFD2_k127_3545253_8 Phosphoribulokinase / Uridine kinase family K00855,K00876 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.19,2.7.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000006087 260.0
HFD2_k127_3545253_9 Branched-chain amino acid transport system / permease component K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004884 274.0
HFD2_k127_3576873_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 461.0
HFD2_k127_3576873_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 428.0
HFD2_k127_3576873_10 - - - - 0.0000000000000000000278 102.0
HFD2_k127_3576873_11 - - - - 0.0000000000003966 82.0
HFD2_k127_3576873_12 Sigma-70, region 4 K03088 - - 0.0000002655 59.0
HFD2_k127_3576873_2 Beta-ketoacyl synthase, N-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007171 396.0
HFD2_k127_3576873_3 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 351.0
HFD2_k127_3576873_4 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000001321 277.0
HFD2_k127_3576873_5 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002144 248.0
HFD2_k127_3576873_6 phosphoserine phosphatase activity K01768,K07315 - 3.1.3.3,4.6.1.1 0.00000000000000000000000000000000000000000000000000000007843 218.0
HFD2_k127_3576873_7 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000005382 199.0
HFD2_k127_3576873_8 PFAM Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000004652 130.0
HFD2_k127_3576873_9 MgtC family K07507 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000001428 114.0
HFD2_k127_3587342_0 MacB-like periplasmic core domain - - - 0.0 1023.0
HFD2_k127_3587342_1 - - - - 7.329e-196 636.0
HFD2_k127_3587342_10 Bacterial protein of unknown function (DUF883) - - - 0.00000000000000000000005898 101.0
HFD2_k127_3587342_11 membrane - - - 0.00000001388 64.0
HFD2_k127_3587342_12 glycosyl hydrolase, BNR repeat-containing protein - - - 0.00001883 57.0
HFD2_k127_3587342_13 YqjK-like protein - - - 0.00003872 54.0
HFD2_k127_3587342_14 Belongs to the glycosyl hydrolase 13 family - - - 0.000404 53.0
HFD2_k127_3587342_2 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004626 336.0
HFD2_k127_3587342_3 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002353 314.0
HFD2_k127_3587342_4 region 4 type 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000007474 241.0
HFD2_k127_3587342_5 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000000000000000001443 184.0
HFD2_k127_3587342_6 - - - - 0.0000000000000000000000000000000000000000000000004329 183.0
HFD2_k127_3587342_7 FR47-like protein - - - 0.00000000000000000000000000000000000007422 153.0
HFD2_k127_3587342_8 - - - - 0.000000000000000000000001805 106.0
HFD2_k127_3587342_9 Domain of unknown function (DUF4386) - - - 0.000000000000000000000009878 112.0
HFD2_k127_3618991_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 8.024e-298 930.0
HFD2_k127_3618991_1 Sodium/calcium exchanger protein K07300 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 398.0
HFD2_k127_3618991_2 DNA methyltransferase K07318 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 372.0
HFD2_k127_3618991_3 Conserved hypothetical protein 698 - - - 0.00000000000000000000000000000000000000000000000000000000004763 218.0
HFD2_k127_3618991_4 - - - - 0.00000000000000000000000000000000000000000000000000000002251 210.0
HFD2_k127_3618991_6 methyltransferase activity - - - 0.000000000000000000000000008964 126.0
HFD2_k127_3618991_7 Alkylmercury lyase - - - 0.00000000000000000008395 95.0
HFD2_k127_3618991_8 histone H2A K63-linked ubiquitination - - - 0.00000000000009228 78.0
HFD2_k127_3618991_9 Alkylmercury lyase - - - 0.0000001012 56.0
HFD2_k127_3623413_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 385.0
HFD2_k127_3623413_1 Helix-hairpin-helix motif K02237 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003874 387.0
HFD2_k127_3623413_10 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000001444 77.0
HFD2_k127_3623413_12 long-chain fatty acid transport protein K06076 - - 0.000000004619 68.0
HFD2_k127_3623413_13 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.0001717 55.0
HFD2_k127_3623413_2 Belongs to the 5'-nucleotidase family K01081,K11751,K17224 - 3.1.3.5,3.6.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005227 331.0
HFD2_k127_3623413_3 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit K01768,K07315 - 3.1.3.3,4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002506 294.0
HFD2_k127_3623413_4 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003253 289.0
HFD2_k127_3623413_5 photosystem II stabilization K02237 - - 0.00000000000000000000000000000000000001991 156.0
HFD2_k127_3623413_6 Metallo-beta-lactamase superfamily K02238 - - 0.000000000000000000000000000002491 140.0
HFD2_k127_3623413_7 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000004228 138.0
HFD2_k127_3623413_8 - - - - 0.00000000000000006067 93.0
HFD2_k127_3623413_9 - K01083 - 3.1.3.8 0.0000000000000007853 93.0
HFD2_k127_3630498_0 von Willebrand factor (vWF) type A domain - - - 1.117e-197 642.0
HFD2_k127_3630498_1 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004596 471.0
HFD2_k127_3630498_10 Nad-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 310.0
HFD2_k127_3630498_11 PFAM Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 298.0
HFD2_k127_3630498_12 epimerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002075 239.0
HFD2_k127_3630498_13 Protein of unknown function (DUF1385) - - - 0.0000000000000000000000000000000000000000000000000000000000000000005852 243.0
HFD2_k127_3630498_14 Enoyl-(Acyl carrier protein) reductase K00023,K00059 - 1.1.1.100,1.1.1.36 0.00000000000000000000000000000000000000000000000000000000000001616 226.0
HFD2_k127_3630498_15 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000003137 206.0
HFD2_k127_3630498_16 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000001863 192.0
HFD2_k127_3630498_17 Elongation factor SelB winged helix 3 K03833 - - 0.000000000000000000000000000000000000000000000001834 176.0
HFD2_k127_3630498_18 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.000000000000000000000000000000000000000000000003783 184.0
HFD2_k127_3630498_19 Nucleotidyl transferase - - - 0.000000000000000000000000000000000002636 157.0
HFD2_k127_3630498_2 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 457.0
HFD2_k127_3630498_20 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000001175 132.0
HFD2_k127_3630498_21 domain, Protein - - - 0.0000000000000000000000001323 124.0
HFD2_k127_3630498_22 Protein of unknown function (DUF1684) K09164 - - 0.0000000000000000000000018 117.0
HFD2_k127_3630498_23 PFAM Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.000000000000000002286 99.0
HFD2_k127_3630498_24 Binds the 23S rRNA K02909 GO:0008150,GO:0040007 - 0.000000000000000003363 94.0
HFD2_k127_3630498_25 - K02450 - - 0.0000000000000000168 98.0
HFD2_k127_3630498_27 AAA domain K02450 - - 0.0000000000001606 84.0
HFD2_k127_3630498_29 Exodeoxyribonuclease III - - - 0.000005473 60.0
HFD2_k127_3630498_3 P-loop ATPase protein family K06958,K07102 GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.1.221 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004303 467.0
HFD2_k127_3630498_4 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 463.0
HFD2_k127_3630498_5 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 415.0
HFD2_k127_3630498_6 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 378.0
HFD2_k127_3630498_7 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 396.0
HFD2_k127_3630498_8 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005524 388.0
HFD2_k127_3630498_9 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07538 - 1.1.1.368 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 380.0
HFD2_k127_3647751_0 Belongs to the ATP-dependent AMP-binding enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004728 456.0
HFD2_k127_3647751_1 PFAM acyl-CoA dehydrogenase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003279 420.0
HFD2_k127_3647751_10 Phosphopantetheine attachment site - - - 0.000000001782 70.0
HFD2_k127_3647751_11 thiolester hydrolase activity K06889 - - 0.000000004764 67.0
HFD2_k127_3647751_12 Protein of unknown function (DUF420) K08976 - - 0.0009014 46.0
HFD2_k127_3647751_2 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 332.0
HFD2_k127_3647751_3 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000009611 232.0
HFD2_k127_3647751_4 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000023 211.0
HFD2_k127_3647751_5 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000005711 218.0
HFD2_k127_3647751_6 Glycogen debranching enzyme N terminal - - - 0.00000000000000002756 98.0
HFD2_k127_3647751_7 Divergent polysaccharide deacetylase K09798 - - 0.00000000000000645 88.0
HFD2_k127_3647751_8 HEAT repeats - - - 0.000000000001181 79.0
HFD2_k127_3647751_9 Serine aminopeptidase, S33 - - - 0.00000000004922 74.0
HFD2_k127_3752598_0 Belongs to the ABC transporter superfamily K02031,K02032,K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 406.0
HFD2_k127_3752598_1 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 386.0
HFD2_k127_3752598_2 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000001742 178.0
HFD2_k127_3752598_3 PFAM Binding-protein-dependent transport system inner membrane component K00759,K02033 - 2.4.2.7 0.0000000000000000000000000001519 116.0
HFD2_k127_3767000_0 Outer membrane protein beta-barrel family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005503 603.0
HFD2_k127_3767000_1 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000001101 154.0
HFD2_k127_3767000_2 Tetratricopeptide repeats - - - 0.0003353 53.0
HFD2_k127_3805076_0 Belongs to the aldehyde dehydrogenase family K00128,K00138 - 1.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005023 584.0
HFD2_k127_3805076_1 Acyclic terpene utilisation family protein AtuA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 592.0
HFD2_k127_3805076_10 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000002599 218.0
HFD2_k127_3805076_11 involved in cell wall biogenesis - - - 0.000000000000000000000000000000000000000000000000000000002576 204.0
HFD2_k127_3805076_12 BioY family K02014,K03523 - - 0.000000000000000000000000000000000000000000000005337 181.0
HFD2_k127_3805076_13 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000002573 186.0
HFD2_k127_3805076_14 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000003235 165.0
HFD2_k127_3805076_15 - - - - 0.00000000000000000000001344 113.0
HFD2_k127_3805076_16 receptor K16087,K16089 - - 0.00000000000000000000002196 117.0
HFD2_k127_3805076_17 FMN-binding domain protein - - - 0.0000000000000000000001652 111.0
HFD2_k127_3805076_19 - - - - 0.0000000000000008557 78.0
HFD2_k127_3805076_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 449.0
HFD2_k127_3805076_20 Outer membrane protein beta-barrel domain - - - 0.00000000000003628 81.0
HFD2_k127_3805076_21 COG0810 Periplasmic protein TonB, links inner and outer membranes K03832 - - 0.000004162 58.0
HFD2_k127_3805076_22 SMART iron dependent repressor K03709 - - 0.000009817 54.0
HFD2_k127_3805076_23 lactoylglutathione lyase activity K00941,K01724,K01759,K07032,K08234 - 2.7.1.49,2.7.4.7,4.2.1.96,4.4.1.5 0.00002836 56.0
HFD2_k127_3805076_24 metallopeptidase activity K01193,K01212,K02809,K02810,K03332,K18775,K19668 GO:0003674,GO:0003824,GO:0004553,GO:0004564,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005984,GO:0005985,GO:0005987,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016052,GO:0016787,GO:0016798,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044424,GO:0044464,GO:0046352,GO:0071704,GO:1901575 2.7.1.211,3.2.1.26,3.2.1.64,3.2.1.65,3.2.1.80,3.2.1.91 0.00009412 53.0
HFD2_k127_3805076_25 DinB superfamily - - - 0.0001627 53.0
HFD2_k127_3805076_26 - - - - 0.0004174 55.0
HFD2_k127_3805076_3 Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed K00626 GO:0003674,GO:0003824,GO:0003988,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004674 371.0
HFD2_k127_3805076_4 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 351.0
HFD2_k127_3805076_5 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005746 342.0
HFD2_k127_3805076_6 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 353.0
HFD2_k127_3805076_8 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006312 313.0
HFD2_k127_3805076_9 - K12065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001794 286.0
HFD2_k127_3805077_0 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 457.0
HFD2_k127_3805077_1 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000003506 229.0
HFD2_k127_3805077_2 YceI-like domain - - - 0.0000000000000000000000000000000000000000002882 169.0
HFD2_k127_3805077_3 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000004807 166.0
HFD2_k127_3805077_4 Subtilase family - - - 0.00000007173 63.0
HFD2_k127_3805077_5 PFAM blue (type 1) copper domain protein - - - 0.000004057 58.0
HFD2_k127_3810561_0 coagulation factor 5 8 type - - - 6.67e-237 759.0
HFD2_k127_3850508_0 Quinolinate synthetase A protein K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 419.0
HFD2_k127_3850508_1 e3 binding domain K00658,K09699 GO:0003674,GO:0003824,GO:0004149,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008289,GO:0009060,GO:0009987,GO:0015980,GO:0016417,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016751,GO:0016999,GO:0017144,GO:0019752,GO:0031405,GO:0031406,GO:0032991,GO:0033293,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:0140096,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234 2.3.1.168,2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 339.0
HFD2_k127_3850508_10 COG3209 Rhs family protein - - - 0.00000000004515 76.0
HFD2_k127_3850508_11 PFAM PKD domain containing protein - - - 0.0000004735 63.0
HFD2_k127_3850508_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009263 317.0
HFD2_k127_3850508_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000116 306.0
HFD2_k127_3850508_4 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03644,K03801 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181,2.8.1.8 0.000000000000000000000000000000000000000000000000000003845 201.0
HFD2_k127_3850508_5 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000015 198.0
HFD2_k127_3850508_6 thioesterase - - - 0.00000000000000000000000000000000000006248 151.0
HFD2_k127_3850508_7 Belongs to the HesB IscA family K13628 - - 0.000000000000000000000005103 114.0
HFD2_k127_3850508_8 Uncharacterized conserved protein (DUF2203) - - - 0.00000000000000003255 89.0
HFD2_k127_3850508_9 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000484 79.0
HFD2_k127_3853818_0 Type II IV secretion system protein K02454,K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 526.0
HFD2_k127_3853818_1 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit K01768,K07315 - 3.1.3.3,4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004789 446.0
HFD2_k127_3853818_2 Tryptophanyl-tRNA synthetase K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007578 366.0
HFD2_k127_3853818_3 Belongs to the pseudouridine synthase RsuA family K06178 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000002502 241.0
HFD2_k127_3853818_4 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000001257 177.0
HFD2_k127_3853818_5 Cupin superfamily (DUF985) K09705 - - 0.0000000000000000000000000000000000001025 153.0
HFD2_k127_3853818_6 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000005315 136.0
HFD2_k127_387518_0 5'-nucleotidase K01081,K01119,K11751 - 3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 529.0
HFD2_k127_387518_1 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 348.0
HFD2_k127_387518_2 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000002297 207.0
HFD2_k127_387518_3 Calcineurin-like phosphoesterase K03269 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.54 0.00000000000000000000000000000000000000000000000001747 192.0
HFD2_k127_387518_4 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) K00382 - 1.8.1.4 0.000000000000000000000000000000000000009099 150.0
HFD2_k127_387518_5 long-chain fatty acid transporting porin activity - - - 0.0000001615 63.0
HFD2_k127_387518_6 Tetratricopeptide TPR_2 repeat protein - - - 0.00001064 57.0
HFD2_k127_3887003_0 elongation factor Tu domain 2 protein K02355 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005494 599.0
HFD2_k127_3887003_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005423 430.0
HFD2_k127_3887003_2 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003576 354.0
HFD2_k127_3887003_3 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000006561 240.0
HFD2_k127_3887003_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0000217,GO:0000400,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.0000000000000000000000000000000000000001868 160.0
HFD2_k127_3887003_5 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000003321 136.0
HFD2_k127_3887003_6 cytochrome C K00406 - - 0.0000006412 57.0
HFD2_k127_3909637_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01535,K01537 - 3.6.3.6,3.6.3.8 3.373e-265 845.0
HFD2_k127_3909637_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006365 623.0
HFD2_k127_3909637_10 PFAM Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000004562 190.0
HFD2_k127_3909637_11 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000007709 189.0
HFD2_k127_3909637_12 NUDIX domain - - - 0.000000000000000000000000000000000000004928 154.0
HFD2_k127_3909637_13 cellulose binding - - - 0.00000000000000000000000000000000006606 151.0
HFD2_k127_3909637_14 B3/4 domain - - - 0.000000000000000000000000000000003094 139.0
HFD2_k127_3909637_15 PDZ DHR GLGF domain protein - - - 0.00000000000000000000007408 112.0
HFD2_k127_3909637_16 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000002751 87.0
HFD2_k127_3909637_17 response regulator, receiver K02030,K13040 - 2.7.13.3 0.000000000001126 80.0
HFD2_k127_3909637_18 Aminotransferase class-V K04127 - 5.1.1.17 0.000000000002349 75.0
HFD2_k127_3909637_19 RNA-binding protein containing a PIN domain K06962 - - 0.0000001251 60.0
HFD2_k127_3909637_2 Rhodanese Homology Domain K01069,K03797 - 3.1.2.6,3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 479.0
HFD2_k127_3909637_20 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 0.000007443 59.0
HFD2_k127_3909637_21 Periplasmic or secreted lipoprotein - - - 0.0001156 53.0
HFD2_k127_3909637_3 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 373.0
HFD2_k127_3909637_4 tRNA (Uracil-5-)-methyltransferase K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004479 339.0
HFD2_k127_3909637_5 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002771 321.0
HFD2_k127_3909637_6 Domain of unknown function (DUF4162) K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002601 262.0
HFD2_k127_3909637_7 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001352 271.0
HFD2_k127_3909637_8 Peptide methionine sulfoxide reductase K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000008431 229.0
HFD2_k127_3909637_9 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000000000000000000004467 217.0
HFD2_k127_3964064_0 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006154 321.0
HFD2_k127_3964064_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007485 314.0
HFD2_k127_3964064_10 Cell division cycle protein 27 homolog K03350 GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464 - 0.0000000001205 71.0
HFD2_k127_3964064_11 GxGYxYP putative glycoside hydrolase C-terminal domain K03088 - - 0.0000000002501 76.0
HFD2_k127_3964064_12 - - - - 0.0000001885 65.0
HFD2_k127_3964064_2 Pkd domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 337.0
HFD2_k127_3964064_3 Cys/Met metabolism PLP-dependent enzyme K01739,K01760,K01761,K17217 - 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.2,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 297.0
HFD2_k127_3964064_4 Lactonase, 7-bladed beta-propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002551 273.0
HFD2_k127_3964064_5 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000005345 211.0
HFD2_k127_3964064_6 GAF domain-containing protein K08968 - 1.8.4.14 0.00000000000000000000000000000000000000000000000000004353 197.0
HFD2_k127_3964064_7 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000002502 181.0
HFD2_k127_3964064_8 PFAM Glycosyltransferase family 9 (heptosyltransferase) K02843,K02849 - - 0.000000000000000000000004871 119.0
HFD2_k127_3964064_9 protein secretion - - - 0.00000000002383 77.0
HFD2_k127_4051315_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.707e-276 877.0
HFD2_k127_4051315_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005089 572.0
HFD2_k127_4051315_10 Biopolymer transport protein ExbD/TolR - - - 0.000000000000000005976 90.0
HFD2_k127_4051315_11 -O-antigen K18814 - - 0.000000000000206 83.0
HFD2_k127_4051315_12 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000000002609 76.0
HFD2_k127_4051315_13 YCII-related domain - - - 0.0000000007885 68.0
HFD2_k127_4051315_14 Putative zinc-finger - - - 0.000000004486 61.0
HFD2_k127_4051315_16 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.0001492 49.0
HFD2_k127_4051315_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 415.0
HFD2_k127_4051315_3 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000449 386.0
HFD2_k127_4051315_4 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007487 289.0
HFD2_k127_4051315_5 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009427 319.0
HFD2_k127_4051315_6 D-isomer specific 2-hydroxyacid dehydrogenase K00058,K16843 - 1.1.1.310,1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000001954 272.0
HFD2_k127_4051315_7 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000007124 181.0
HFD2_k127_4051315_8 MotA/TolQ/ExbB proton channel family - - - 0.00000000000000000000000001678 121.0
HFD2_k127_410071_0 PEP-utilising enzyme, mobile domain K01006 - 2.7.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008219 409.0
HFD2_k127_410071_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 0.00000000000003486 86.0
HFD2_k127_4122102_0 - Amino acid transport and metabolism K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007555 484.0
HFD2_k127_4122102_1 UDP binding domain K00066 - 1.1.1.132 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 432.0
HFD2_k127_4122102_10 O-methyltransferase activity - - - 0.00000000000000000000000000001453 130.0
HFD2_k127_4122102_11 Glycosyl transferase family 2 - - - 0.00000000000000000000000000006646 125.0
HFD2_k127_4122102_12 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000001317 133.0
HFD2_k127_4122102_13 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000003313 108.0
HFD2_k127_4122102_14 - - - - 0.000000000000000001593 101.0
HFD2_k127_4122102_15 PFAM Glycosyl transferase, group 1 - - - 0.00000000003465 77.0
HFD2_k127_4122102_16 Pfam Glycosyl transferase family 2 - - - 0.000000001864 71.0
HFD2_k127_4122102_2 Glycosyl transferase 4-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005162 389.0
HFD2_k127_4122102_3 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 361.0
HFD2_k127_4122102_4 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009237 332.0
HFD2_k127_4122102_5 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005645 317.0
HFD2_k127_4122102_6 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001071 248.0
HFD2_k127_4122102_7 Nucleotidyl transferase K00971 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000002353 248.0
HFD2_k127_4122102_8 Sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001598 241.0
HFD2_k127_4122102_9 Glycosyl transferase group 1 - - - 0.000000000000000000000000000000000006096 158.0
HFD2_k127_415221_0 PFAM IstB domain protein ATP-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000455 401.0
HFD2_k127_415221_1 PFAM Integrase catalytic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004057 321.0
HFD2_k127_415221_2 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.000000000000000000000000000000000000000009563 163.0
HFD2_k127_415221_3 PFAM Integrase catalytic - - - 0.00000000000000000000000000000000000003087 153.0
HFD2_k127_415221_4 reverse transcriptase - - - 0.00007437 47.0
HFD2_k127_4152856_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 1.575e-251 796.0
HFD2_k127_4152856_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 4.878e-214 701.0
HFD2_k127_4152856_10 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000008372 108.0
HFD2_k127_4152856_11 Participates in both transcription termination and antitermination K02600 GO:0001000,GO:0001121,GO:0001125,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000001866 100.0
HFD2_k127_4152856_12 PFAM Polysaccharide export protein - - - 0.0000000000000000002364 98.0
HFD2_k127_4152856_13 Protein of unknown function (DUF503) K09764 - - 0.000000000000005922 79.0
HFD2_k127_4152856_14 biosynthesis protein - - - 0.000000000001457 78.0
HFD2_k127_4152856_15 protein involved in exopolysaccharide biosynthesis K16554 - - 0.0002837 53.0
HFD2_k127_4152856_2 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 362.0
HFD2_k127_4152856_3 Belongs to the peptidase M16 family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 322.0
HFD2_k127_4152856_4 peptidyl-lysine modification to peptidyl-hypusine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 306.0
HFD2_k127_4152856_5 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000003654 229.0
HFD2_k127_4152856_6 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000004251 209.0
HFD2_k127_4152856_7 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000004469 193.0
HFD2_k127_4152856_8 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000000000001156 173.0
HFD2_k127_4152856_9 Ribosomal_S15 K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000006798 132.0
HFD2_k127_4211535_0 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004601 308.0
HFD2_k127_4211535_1 L-lysine 6-monooxygenase (NADPH-requiring) K07222 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 301.0
HFD2_k127_4211535_2 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006149 316.0
HFD2_k127_4211535_3 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000002318 169.0
HFD2_k127_4211535_4 Antibiotic biosynthesis monooxygenase K11530 - 5.3.1.32 0.00000000000000000000000001349 115.0
HFD2_k127_4211535_5 Protein of unknown function (DUF861) K06995 - - 0.0000000000000000005586 92.0
HFD2_k127_4211535_6 Belongs to the glycosyl hydrolase 32 family K01193 - 3.2.1.26 0.0000002101 64.0
HFD2_k127_4343721_0 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004464 248.0
HFD2_k127_4343721_1 Hemerythrin HHE cation binding domain - - - 0.00000006661 64.0
HFD2_k127_440210_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.541e-274 872.0
HFD2_k127_440210_1 Fumarate reductase flavoprotein C-term K00239,K00244 - 1.3.5.1,1.3.5.4 6.489e-239 805.0
HFD2_k127_440210_10 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005215 382.0
HFD2_k127_440210_11 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004345 363.0
HFD2_k127_440210_12 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 358.0
HFD2_k127_440210_13 PFAM aminotransferase class I and II K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003821 355.0
HFD2_k127_440210_14 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008013 337.0
HFD2_k127_440210_15 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005781 351.0
HFD2_k127_440210_16 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 334.0
HFD2_k127_440210_17 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003736 313.0
HFD2_k127_440210_18 Glycosyltransferase family 28 C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 295.0
HFD2_k127_440210_19 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000003064 274.0
HFD2_k127_440210_2 von Willebrand factor, type A K07114 - - 3.021e-208 668.0
HFD2_k127_440210_20 Peptidase dimerisation domain K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000007597 273.0
HFD2_k127_440210_21 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000187 258.0
HFD2_k127_440210_22 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006309 274.0
HFD2_k127_440210_23 Deoxynucleoside kinase K15518 - 2.7.1.113 0.0000000000000000000000000000000000000000000000000000000000000000003402 244.0
HFD2_k127_440210_24 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000002934 239.0
HFD2_k127_440210_25 Glycosyltransferase family 28 C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000002251 226.0
HFD2_k127_440210_26 Belongs to the RtcB family K14415 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000006609 227.0
HFD2_k127_440210_27 Transcriptional regulatory protein, C terminal K07658,K07668 - - 0.0000000000000000000000000000000000000000000000000000000003219 215.0
HFD2_k127_440210_28 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000159 224.0
HFD2_k127_440210_29 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000008982 205.0
HFD2_k127_440210_3 Uncharacterized protein conserved in bacteria (DUF2344) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 591.0
HFD2_k127_440210_30 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000000003427 205.0
HFD2_k127_440210_31 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000007667 213.0
HFD2_k127_440210_32 protein related to plant photosystem II stability assembly factor - - - 0.0000000000000000000000000000000000000000000002744 180.0
HFD2_k127_440210_33 Histidine kinase HAMP - - - 0.000000000000000000000000000000000000000000002223 179.0
HFD2_k127_440210_34 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00241 - - 0.00000000000000000000000000000000000000000002633 175.0
HFD2_k127_440210_35 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950,K13940 - 2.7.6.3,4.1.2.25 0.00000000000000000000000000000000000000000007914 168.0
HFD2_k127_440210_36 Hit family K19710 - 2.7.7.53 0.00000000000000000000000000000000000001813 160.0
HFD2_k127_440210_37 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.00000000000000000000000000000000006422 145.0
HFD2_k127_440210_38 Peptidylprolyl isomerase K03769,K03770,K03771 - 5.2.1.8 0.0000000000000000000000000000000007338 151.0
HFD2_k127_440210_39 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.00000000000000000000000000000007747 135.0
HFD2_k127_440210_4 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0001817,GO:0001819,GO:0001871,GO:0002791,GO:0002793,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009986,GO:0009987,GO:0016465,GO:0030246,GO:0030247,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044764,GO:0046812,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051082,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051704,GO:0061077,GO:0065007,GO:0070201,GO:0090087,GO:0098630,GO:0098743,GO:0101031,GO:1903530,GO:1903532,GO:1904951,GO:1990220,GO:2000482,GO:2000484,GO:2001065 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004168 460.0
HFD2_k127_440210_40 Belongs to the eIF-2B alpha beta delta subunits family K03680 - - 0.0000000000000000000000000004658 126.0
HFD2_k127_440210_41 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000000000000000014 117.0
HFD2_k127_440210_42 PFAM outer membrane efflux protein - - - 0.00000000000000000000003264 114.0
HFD2_k127_440210_43 Galactose oxidase, central domain - - - 0.00000000000000000002961 104.0
HFD2_k127_440210_44 - - - - 0.000000000000000002706 93.0
HFD2_k127_440210_45 folic acid binding K00605,K06980 GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0051186,GO:0071840 2.1.2.10 0.000000000000000003588 94.0
HFD2_k127_440210_46 Phosphotransferase enzyme family - - - 0.000000000000002193 88.0
HFD2_k127_440210_47 Phosphotransferase enzyme family - - - 0.000000000000006248 90.0
HFD2_k127_440210_48 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.000000000000007241 79.0
HFD2_k127_440210_49 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000001161 76.0
HFD2_k127_440210_5 ABC-type multidrug transport system ATPase and permease K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004518 455.0
HFD2_k127_440210_51 ethanolamine kinase activity K07251 - 2.7.1.89 0.000000000001831 82.0
HFD2_k127_440210_52 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.163,2.1.1.201 0.00000000002701 75.0
HFD2_k127_440210_53 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000006764 65.0
HFD2_k127_440210_54 - - - - 0.0000002954 61.0
HFD2_k127_440210_55 PFAM Cell envelope-related transcriptional attenuator domain - - - 0.000003769 57.0
HFD2_k127_440210_57 Evidence 5 No homology to any previously reported sequences - - - 0.00001919 58.0
HFD2_k127_440210_58 Phosphotransferase enzyme family - - - 0.00002784 55.0
HFD2_k127_440210_6 Ribonuclease E/G family K08301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 437.0
HFD2_k127_440210_7 ABC transporter transmembrane region K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007931 439.0
HFD2_k127_440210_8 Domains REC, sigma54 interaction, HTH8 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 398.0
HFD2_k127_440210_9 Bacterial Ig-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005216 385.0
HFD2_k127_4423678_0 response regulator K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000001324 248.0
HFD2_k127_4423678_1 TIGR00255 family - - - 0.0000000000000000000000000000000000000000000000000000000000000003217 231.0
HFD2_k127_4423678_2 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.000000000000000000000000000000000000000000000004735 188.0
HFD2_k127_4441465_0 PFAM peptidase S9 prolyl oligopeptidase active site domain protein K01322,K01354 - 3.4.21.26,3.4.21.83 3.965e-229 731.0
HFD2_k127_4441465_1 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 548.0
HFD2_k127_4441465_10 domain protein - - - 0.000000000000000000000000000006001 135.0
HFD2_k127_4441465_11 - K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.00000000000000000000000000008619 124.0
HFD2_k127_4441465_12 - - - - 0.00000000000000000000000006338 122.0
HFD2_k127_4441465_13 - - - - 0.000000000000002099 89.0
HFD2_k127_4441465_2 PFAM aminotransferase, class I K10907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 529.0
HFD2_k127_4441465_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005451 355.0
HFD2_k127_4441465_4 Pkd domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001747 297.0
HFD2_k127_4441465_5 PFAM PKD domain containing protein K11751 - 3.1.3.5,3.6.1.45 0.00000000000000000000000000000000000000000000000000000000000000000003746 250.0
HFD2_k127_4441465_6 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000007948 209.0
HFD2_k127_4441465_7 COG0145 N-methylhydantoinase A acetone carboxylase, beta subunit K01473 - 3.5.2.14 0.000000000000000000000000000000000000000000000000006326 194.0
HFD2_k127_4441465_8 Fibronectin type 3 domain - - - 0.00000000000000000000000000000000000001033 168.0
HFD2_k127_4451701_0 PFAM peptidase M61 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004425 613.0
HFD2_k127_4451701_1 Secreted protein containing N-terminal Zinc-dependent carboxypeptidase related domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000669 584.0
HFD2_k127_4451701_10 PFAM Glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.000000000000002684 87.0
HFD2_k127_4451701_2 metallocarboxypeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 475.0
HFD2_k127_4451701_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004919 297.0
HFD2_k127_4451701_4 AIR synthase related protein, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002644 285.0
HFD2_k127_4451701_5 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000001283 229.0
HFD2_k127_4451701_6 PFAM fumarate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000003133 224.0
HFD2_k127_4451701_7 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000242 196.0
HFD2_k127_4451701_8 Pkd domain containing protein - - - 0.000000000000000000000000000000000000000000002317 177.0
HFD2_k127_4451701_9 O-acyltransferase activity K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000008166 145.0
HFD2_k127_4476986_0 response regulator K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007873 382.0
HFD2_k127_4476986_1 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000000129 196.0
HFD2_k127_4476986_2 CAAX protease self-immunity - - - 0.00000000004677 72.0
HFD2_k127_4481172_0 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 482.0
HFD2_k127_4481172_1 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009275 471.0
HFD2_k127_4481172_10 Belongs to the 'phage' integrase family - - - 0.0000000000000000001969 101.0
HFD2_k127_4481172_11 - - - - 0.0000001337 59.0
HFD2_k127_4481172_12 cell adhesion involved in biofilm formation - - - 0.0000002081 63.0
HFD2_k127_4481172_2 dicarboxylic acid transport K03309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 417.0
HFD2_k127_4481172_3 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 329.0
HFD2_k127_4481172_4 Pyridoxal-phosphate dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 317.0
HFD2_k127_4481172_5 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009887 290.0
HFD2_k127_4481172_6 PFAM aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000008489 218.0
HFD2_k127_4481172_7 Resolvase, N terminal domain - - - 0.000000000000000000000000000000000000001013 155.0
HFD2_k127_4481172_8 thiolester hydrolase activity K06889 - - 0.00000000000000000000000000000004133 141.0
HFD2_k127_4481172_9 Belongs to the ferrochelatase family K01772 - 4.99.1.1,4.99.1.9 0.00000000000000000001407 106.0
HFD2_k127_4481881_0 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004398 477.0
HFD2_k127_4481881_1 Permease YjgP YjgQ family protein K07091,K11720 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 314.0
HFD2_k127_4481881_2 Permease YjgP YjgQ K11720 - - 0.00000000000000000000000000000000000000000000005156 194.0
HFD2_k127_4481881_3 Belongs to the ComB family K05979 GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545 3.1.3.71 0.0000007615 54.0
HFD2_k127_4481881_4 PFAM Peptidase family M28 - - - 0.0002743 47.0
HFD2_k127_4493816_0 Sulfatase - - - 4.382e-276 858.0
HFD2_k127_4493816_1 Sulfate permease family - - - 1.021e-251 789.0
HFD2_k127_4493816_10 Methyltransferase domain - - - 0.00000000000000000000000000000000000008161 148.0
HFD2_k127_4493816_11 YCII-related domain - - - 0.00000000000000000000000000000000007827 145.0
HFD2_k127_4493816_12 PFAM Rhodanese domain protein K03972 GO:0003674,GO:0003824,GO:0004792,GO:0005575,GO:0005623,GO:0016740,GO:0016782,GO:0016783,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - 0.00000000000000000000003872 105.0
HFD2_k127_4493816_13 Transposase - - - 0.00000001905 65.0
HFD2_k127_4493816_14 ig-like, plexins, transcription factors - - - 0.0000001157 62.0
HFD2_k127_4493816_2 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009026 531.0
HFD2_k127_4493816_3 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000401 482.0
HFD2_k127_4493816_4 Transmembrane secretion effector K08225 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 370.0
HFD2_k127_4493816_5 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 359.0
HFD2_k127_4493816_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 351.0
HFD2_k127_4493816_7 Conserved hypothetical protein (DUF2461) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004334 279.0
HFD2_k127_4493816_8 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001103 280.0
HFD2_k127_4493816_9 Uncharacterized protein conserved in bacteria (DUF2087) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002599 264.0
HFD2_k127_4502734_0 Glutamine synthetase, catalytic region K01915 - 6.3.1.2 7.542e-243 773.0
HFD2_k127_4502734_1 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003916 604.0
HFD2_k127_4502734_10 PFAM glycosyl transferase family 9 K02843 - - 0.000000000000000000194 102.0
HFD2_k127_4502734_11 protein conserved in bacteria K09800 - - 0.000000000008678 80.0
HFD2_k127_4502734_13 LVIVD repeat K01179 - 3.2.1.4 0.00004035 56.0
HFD2_k127_4502734_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000004801 272.0
HFD2_k127_4502734_3 Peptidase family M50 K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000002378 241.0
HFD2_k127_4502734_4 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000001556 218.0
HFD2_k127_4502734_5 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000009624 181.0
HFD2_k127_4502734_6 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000009324 162.0
HFD2_k127_4502734_7 Glycosyl transferase family 2 K12984 - - 0.00000000000000000000000000000000000002142 154.0
HFD2_k127_4502734_8 Surface antigen K07277 - - 0.0000000000000000000000000000000000009529 160.0
HFD2_k127_4502734_9 Glycosyl transferases group 1 - - - 0.00000000000000000000000002342 127.0
HFD2_k127_4526610_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 3.494e-259 841.0
HFD2_k127_4526610_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000009272 252.0
HFD2_k127_4526610_2 peroxiredoxin activity - - - 0.0000000000000000000000000000000000000000004279 177.0
HFD2_k127_4526610_3 Belongs to the ompA family - - - 0.00000000000000000000000000000000000001973 154.0
HFD2_k127_4526610_4 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.00000000000000000001097 97.0
HFD2_k127_4534282_0 Nitronate monooxygenase K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 398.0
HFD2_k127_4534282_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003414 281.0
HFD2_k127_4534282_2 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000066 250.0
HFD2_k127_4534282_3 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000001933 237.0
HFD2_k127_4534282_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.000000000000000000000000000000000000000000000000000007244 196.0
HFD2_k127_4534282_5 Domain of unknown function (DUF4442) - - - 0.000000000000000000000000000000000000008866 158.0
HFD2_k127_4534282_6 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000002363 139.0
HFD2_k127_4534282_7 - - - - 0.0000003583 61.0
HFD2_k127_4534282_8 DNA polymerase K02337,K14162 - 2.7.7.7 0.00005495 48.0
HFD2_k127_4689072_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007391 451.0
HFD2_k127_4689072_1 Transglycosylase K05366 GO:0003674,GO:0005488,GO:0005515,GO:0042802 2.4.1.129,3.4.16.4 0.00000000000000000000000000000001274 134.0
HFD2_k127_4689072_2 - - - - 0.00000000001185 64.0
HFD2_k127_4689943_0 ERAP1-like C-terminal domain K01256,K01263 - 3.4.11.14,3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004745 578.0
HFD2_k127_4689943_1 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 363.0
HFD2_k127_4689943_2 Threonine/Serine exporter, ThrE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 324.0
HFD2_k127_4689943_3 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005458 306.0
HFD2_k127_4689943_4 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.000000000000000000000000000000000000000000000000000000000000000004324 233.0
HFD2_k127_4689943_5 Cupin domain - - - 0.000000000000000000000000000000000000339 143.0
HFD2_k127_4689943_6 Curli production assembly/transport component CsgG - - - 0.0000003172 62.0
HFD2_k127_4689943_7 Pilus assembly protein PilX - - - 0.0000009299 61.0
HFD2_k127_4689943_8 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0002219 54.0
HFD2_k127_4689943_9 amine dehydrogenase activity K20276,K21430 - - 0.000331 52.0
HFD2_k127_4714416_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 377.0
HFD2_k127_4714416_1 Cytochrome c biogenesis protein transmembrane region K04084 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006906 380.0
HFD2_k127_4714416_10 Protein of unknown function, DUF255 K06888 - - 0.0000000000000007121 82.0
HFD2_k127_4714416_11 Mut7-C RNAse domain K09122 - - 0.00000000000001837 80.0
HFD2_k127_4714416_12 DinB superfamily - - - 0.0000000001755 71.0
HFD2_k127_4714416_2 Putative modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005475 263.0
HFD2_k127_4714416_3 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000000000000006256 250.0
HFD2_k127_4714416_4 Glycosyl transferase, family 2 K07011 - - 0.0000000000000000000000000000000000000000000000000000001316 206.0
HFD2_k127_4714416_5 Sterol carrier protein domain - - - 0.000000000000000000000000000000000000000003131 175.0
HFD2_k127_4714416_6 gag-polyprotein putative aspartyl protease - - - 0.000000000000000000000000000001935 140.0
HFD2_k127_4714416_7 Nitroreductase - - - 0.00000000000000000000000000003246 132.0
HFD2_k127_4714416_8 helix_turn_helix, cAMP Regulatory protein K21564 - - 0.000000000000000000000002244 117.0
HFD2_k127_4714416_9 Thioesterase K01075 - 3.1.2.23 0.0000000000000000000001418 102.0
HFD2_k127_472885_0 Glycosyl hydrolase 36 superfamily, catalytic domain K00702,K13688 - 2.4.1.20 0.0 3268.0
HFD2_k127_472885_1 Domains REC, PAS, PAS, PP2C K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000001724 222.0
HFD2_k127_472885_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000001468 156.0
HFD2_k127_472885_3 Cold shock protein K03704 - - 0.000006727 48.0
HFD2_k127_4768319_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 370.0
HFD2_k127_4768319_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 373.0
HFD2_k127_4768319_2 Domain of unknown function (DUF4159) - - - 0.0000000000000000000000000000000000000000000000000000000000000000469 236.0
HFD2_k127_4768319_3 SecD/SecF GG Motif K03074 - - 0.00000000000000000000000000000000000000000000000000000000000349 237.0
HFD2_k127_4768319_4 nuclear chromosome segregation - - - 0.00000005811 65.0
HFD2_k127_4769225_0 Malate synthase K01638 - 2.3.3.9 8.807e-214 676.0
HFD2_k127_4769225_1 BNR/Asp-box repeat - - - 5.285e-205 642.0
HFD2_k127_4769225_10 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000009286 162.0
HFD2_k127_4769225_11 polysaccharide catabolic process K03478 - 3.5.1.105 0.00000000000000000000000000000000001087 157.0
HFD2_k127_4769225_12 methylamine metabolic process K15977 - - 0.00000000000000000000000000000001244 132.0
HFD2_k127_4769225_13 Mo-molybdopterin cofactor metabolic process K03636,K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000000000000001515 143.0
HFD2_k127_4769225_14 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.000000000000000002162 93.0
HFD2_k127_4769225_15 homoserine kinase activity - - - 0.000000000000003714 90.0
HFD2_k127_4769225_16 transferase activity, transferring glycosyl groups - - - 0.00002656 54.0
HFD2_k127_4769225_17 homoserine kinase activity - - - 0.00003769 55.0
HFD2_k127_4769225_18 Aminoglycoside phosphotransferase - - - 0.0003221 54.0
HFD2_k127_4769225_19 Tetratricopeptide repeat - - - 0.0003856 53.0
HFD2_k127_4769225_2 Isocitrate lyase K01637 - 4.1.3.1 3.498e-195 616.0
HFD2_k127_4769225_3 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 602.0
HFD2_k127_4769225_4 Protein of unknown function (DUF2891) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 338.0
HFD2_k127_4769225_5 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 328.0
HFD2_k127_4769225_6 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001052 284.0
HFD2_k127_4769225_7 YCII-related domain - - - 0.000000000000000000000000000000000000000000000000000000000009061 212.0
HFD2_k127_4769225_8 - - - - 0.0000000000000000000000000000000000000000000000000002626 209.0
HFD2_k127_4769225_9 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000001463 190.0
HFD2_k127_4789904_0 H( )-stimulated, divalent metal cation uptake system K03322 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 597.0
HFD2_k127_4789904_1 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 311.0
HFD2_k127_4789904_2 Alpha beta K07018 - - 0.0000000000000000000000000000000000000000004615 172.0
HFD2_k127_4789904_3 iron dependent repressor K03709 - - 0.00000000000000000000000000000000000000007415 159.0
HFD2_k127_4789904_4 Fungalysin metallopeptidase (M36) - - - 0.00000008363 65.0
HFD2_k127_4789904_5 COG1807 4-amino-4-deoxy-L-arabinose transferase and related - - - 0.0000002517 63.0
HFD2_k127_4887296_0 Glycosyl transferase family group 2 K19290 - 2.4.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000621 516.0
HFD2_k127_4887296_1 PFAM secretion protein HlyD family protein K02005,K02022 - - 0.00000000000000000000000000000000000000000000000000002455 208.0
HFD2_k127_4887296_2 Pectate lyase superfamily protein - - - 0.00000000000000000000000000000000002235 150.0
HFD2_k127_4887296_3 Bacterial transcriptional repressor C-terminal - - - 0.000000000000000000000000243 115.0
HFD2_k127_4887296_4 Protein of unknown function (DUF3303) - - - 0.00000000000000000000004632 112.0
HFD2_k127_4887296_5 Unextendable partial coding region - - - 0.000000000005569 68.0
HFD2_k127_4887296_7 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00066 - 1.1.1.132 0.00002564 52.0
HFD2_k127_4945449_0 Pkd domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004034 390.0
HFD2_k127_4945449_1 alginic acid biosynthetic process K07218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001279 265.0
HFD2_k127_495060_0 PglZ domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 546.0
HFD2_k127_495060_1 PA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004728 445.0
HFD2_k127_495060_10 - K13486 - - 0.00004949 56.0
HFD2_k127_495060_2 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744,K09774 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 357.0
HFD2_k127_495060_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 GO:0001676,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0003824,GO:0003989,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006417,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0017148,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032787,GO:0032991,GO:0034248,GO:0034249,GO:0042759,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:0097159,GO:1901363,GO:1901576,GO:1902494,GO:1990234,GO:2000112,GO:2000113 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 310.0
HFD2_k127_495060_4 Oxidoreductase molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003495 288.0
HFD2_k127_495060_5 Cytochrome b/b6/petB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002616 267.0
HFD2_k127_495060_6 PFAM Mur ligase family, glutamate ligase domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000003619 248.0
HFD2_k127_495060_7 Putative adhesin - - - 0.000000000000000000000003684 120.0
HFD2_k127_495060_8 ATPase or kinase K06925 - - 0.0000000000000000000002462 111.0
HFD2_k127_495060_9 Acetyltransferase K03789,K14742 - 2.3.1.128 0.00000000000000000006533 104.0
HFD2_k127_4967159_0 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000002751 279.0
HFD2_k127_4967159_1 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 GO:0003674,GO:0003824,GO:0004016,GO:0009975,GO:0016829,GO:0016849 2.7.7.85 0.000000000000000000000000000000000000000000000000000000000000001067 228.0
HFD2_k127_4967159_2 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000000004616 207.0
HFD2_k127_4967159_3 DinB superfamily - - - 0.00000000000000002774 87.0
HFD2_k127_4972485_0 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 2.374e-211 676.0
HFD2_k127_4972485_1 Cytochrome C and Quinol oxidase polypeptide I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000629 612.0
HFD2_k127_4972485_10 ECF sigma factor - - - 0.000000000000000000000000000000000000001126 155.0
HFD2_k127_4972485_11 Belongs to the complex I 75 kDa subunit family K00336 - 1.6.5.3 0.000000000000000000000000000000000001438 151.0
HFD2_k127_4972485_12 cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000005523 144.0
HFD2_k127_4972485_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000009488 124.0
HFD2_k127_4972485_14 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000001656 128.0
HFD2_k127_4972485_15 domain, Protein - - - 0.000000000000001127 93.0
HFD2_k127_4972485_17 Belongs to the glycosyl hydrolase 13 family - - - 0.0003252 55.0
HFD2_k127_4972485_2 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005279 585.0
HFD2_k127_4972485_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 426.0
HFD2_k127_4972485_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 352.0
HFD2_k127_4972485_5 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003121 271.0
HFD2_k127_4972485_6 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000003922 281.0
HFD2_k127_4972485_7 Cytochrome c oxidase subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000001209 224.0
HFD2_k127_4972485_8 peptidase activity, acting on L-amino acid peptides K20276 - - 0.0000000000000000000000000000000000000000000001228 195.0
HFD2_k127_4972485_9 bleomycin resistance protein - - - 0.0000000000000000000000000000000000000002834 155.0
HFD2_k127_498063_0 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002332 284.0
HFD2_k127_498063_1 Adenosine specific kinase K09129 - - 0.000000000000000000000000000000000000000000000000000000000000001956 222.0
HFD2_k127_498063_10 - - - - 0.000000000985 72.0
HFD2_k127_498063_11 TonB C terminal K03832 - - 0.0000000865 63.0
HFD2_k127_498063_12 cellulase activity K07019 - - 0.0000001887 64.0
HFD2_k127_498063_2 PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP K20276 - - 0.00000000000000000000000000000000000000000000000000000000000001004 242.0
HFD2_k127_498063_3 COG4775 Outer membrane protein protective antigen OMA87 - - - 0.00000000000000000000000000000000001922 154.0
HFD2_k127_498063_4 Glutathione peroxidase K02199 - - 0.00000000000000000000000000000002652 132.0
HFD2_k127_498063_5 OmpA family K03640 - - 0.0000000000000000000000000000007573 130.0
HFD2_k127_498063_6 PFAM MotA TolQ ExbB proton channel K03562 - - 0.000000000000000000000000000001244 132.0
HFD2_k127_498063_7 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.000000000000000000000005767 113.0
HFD2_k127_498063_8 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000001592 105.0
HFD2_k127_498063_9 - - - - 0.0000000000022 75.0
HFD2_k127_5009194_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 505.0
HFD2_k127_5009194_1 PFAM asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004255 407.0
HFD2_k127_5009194_10 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000004811 165.0
HFD2_k127_5009194_11 COG1596 Periplasmic protein involved in polysaccharide export K01991 - - 0.00000000000000000000000000000000003508 156.0
HFD2_k127_5009194_12 Capsule biosynthesis GfcC - - - 0.0000000000000000000000001975 122.0
HFD2_k127_5009194_13 PFAM lipopolysaccharide biosynthesis - - - 0.0000000000000000000000003663 121.0
HFD2_k127_5009194_14 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0008150,GO:0040007 - 0.0000000000000004976 89.0
HFD2_k127_5009194_15 O-Antigen ligase - - - 0.000000000000002628 91.0
HFD2_k127_5009194_16 Belongs to the UPF0109 family K06960 - - 0.000000000004853 74.0
HFD2_k127_5009194_17 COG1596 Periplasmic protein involved in polysaccharide export K20988 - - 0.0003877 54.0
HFD2_k127_5009194_2 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710,K12450 GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 4.2.1.46,4.2.1.76 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 382.0
HFD2_k127_5009194_3 3-beta hydroxysteroid dehydrogenase/isomerase family K01784,K10011,K12449 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006040,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016741,GO:0016742,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0022607,GO:0033319,GO:0033320,GO:0034214,GO:0034641,GO:0034654,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046349,GO:0046483,GO:0046677,GO:0048037,GO:0048040,GO:0050662,GO:0050896,GO:0051259,GO:0051287,GO:0055086,GO:0055114,GO:0065003,GO:0070403,GO:0071704,GO:0071840,GO:0097159,GO:0099618,GO:0099619,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:2001313,GO:2001315 1.1.1.305,2.1.2.13,5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003991 364.0
HFD2_k127_5009194_4 PFAM glycosyl transferase group 1 K12995 - 2.4.1.348 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007342 280.0
HFD2_k127_5009194_5 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000002194 268.0
HFD2_k127_5009194_6 WxcM-like, C-terminal K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000001815 213.0
HFD2_k127_5009194_7 - - - - 0.00000000000000000000000000000000000000000000000000001644 214.0
HFD2_k127_5009194_8 COG2931 RTX toxins and related Ca2 -binding - - - 0.0000000000000000000000000000000000000000001059 183.0
HFD2_k127_5009194_9 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000002002 166.0
HFD2_k127_5009451_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 515.0
HFD2_k127_5009451_1 MreB/Mbl protein K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 459.0
HFD2_k127_5009451_10 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000007469 106.0
HFD2_k127_5009451_11 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.00000000000000507 84.0
HFD2_k127_5009451_12 rod shape-determining protein MreD K03571 - - 0.00000004617 66.0
HFD2_k127_5009451_2 Penicillin-binding protein 2 K05515 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 409.0
HFD2_k127_5009451_3 MgsA AAA+ ATPase C terminal K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 364.0
HFD2_k127_5009451_4 ATPases associated with a variety of cellular activities K02006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 308.0
HFD2_k127_5009451_5 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002392 301.0
HFD2_k127_5009451_6 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000003292 171.0
HFD2_k127_5009451_7 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000505 143.0
HFD2_k127_5009451_8 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000007307 133.0
HFD2_k127_5009451_9 PFAM Cobalt transport protein K02008 - - 0.0000000000000000000005383 110.0
HFD2_k127_5032431_0 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 6.28e-198 631.0
HFD2_k127_5032431_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005498 398.0
HFD2_k127_5032431_10 Ribosomal L32p protein family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.0000000000000000001501 89.0
HFD2_k127_5032431_11 acr, cog1399 K07040 - - 0.0000000000000005041 88.0
HFD2_k127_5032431_12 Short-chain dehydrogenase reductase sdr - - - 0.000799 49.0
HFD2_k127_5032431_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005258 383.0
HFD2_k127_5032431_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002952 377.0
HFD2_k127_5032431_4 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007684 286.0
HFD2_k127_5032431_5 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005561 297.0
HFD2_k127_5032431_6 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000000223 178.0
HFD2_k127_5032431_7 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000009043 167.0
HFD2_k127_5032431_8 Domain of unknown function (DUF4160) - - - 0.00000000000000000000000000002542 119.0
HFD2_k127_5032431_9 Protein of unknown function (DUF2442) - - - 0.0000000000000000000363 93.0
HFD2_k127_507163_0 Di-haem oxidoreductase, putative peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001216 259.0
HFD2_k127_5088871_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 1.733e-300 964.0
HFD2_k127_5088871_1 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 3.869e-286 908.0
HFD2_k127_5088871_10 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K02052 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000493 303.0
HFD2_k127_5088871_11 Biotin-lipoyl like K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007316 272.0
HFD2_k127_5088871_12 Outer membrane efflux protein K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004771 277.0
HFD2_k127_5088871_13 Binding-protein-dependent transport system inner membrane component K02018 - - 0.000000000000000000000000000000000000000000000000000000000000000005611 246.0
HFD2_k127_5088871_14 catechol 1,2-dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000008909 226.0
HFD2_k127_5088871_15 Bacterial extracellular solute-binding protein K02020 - - 0.00000000000000000000000000000000000000000000000000000000000005437 229.0
HFD2_k127_5088871_16 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000003552 224.0
HFD2_k127_5088871_17 NlpE C-terminal OB domain - - - 0.000000000000000000000000000000000000000000000000000000005746 212.0
HFD2_k127_5088871_18 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.000000000000000000000000000000000000000000000000000001524 207.0
HFD2_k127_5088871_19 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07670 GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016310,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000001298 211.0
HFD2_k127_5088871_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 4.556e-245 770.0
HFD2_k127_5088871_20 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000001143 179.0
HFD2_k127_5088871_21 DinB family - - - 0.000000000000000000000000000000000000000003969 168.0
HFD2_k127_5088871_22 TOBE domain - - - 0.0000000000001341 76.0
HFD2_k127_5088871_23 - - - - 0.0000002642 63.0
HFD2_k127_5088871_24 Helix-turn-helix domain - - - 0.0006797 48.0
HFD2_k127_5088871_3 transporter, DctM subunit K11690 - - 1.206e-215 685.0
HFD2_k127_5088871_4 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 1.661e-208 666.0
HFD2_k127_5088871_5 Amino acid permease - - - 6.28e-204 655.0
HFD2_k127_5088871_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000917 545.0
HFD2_k127_5088871_7 Carbohydrate family 9 binding domain-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 368.0
HFD2_k127_5088871_8 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003915 318.0
HFD2_k127_5088871_9 Pkd domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 316.0
HFD2_k127_5089718_0 peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008815 460.0
HFD2_k127_5089718_1 Domain of unknown function (DUF4347) - - - 0.000000000000000000000000000000000000000000000000000000003831 228.0
HFD2_k127_5089718_2 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000004088 158.0
HFD2_k127_5089718_3 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000007417 155.0
HFD2_k127_5089718_4 cell redox homeostasis K02199,K03671 - - 0.00000000000000000000000004059 115.0
HFD2_k127_5089718_5 - - - - 0.00006637 57.0
HFD2_k127_5089718_6 Domain of Unknown Function (DUF350) - - - 0.000725 52.0
HFD2_k127_5092093_0 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 423.0
HFD2_k127_5092093_1 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 323.0
HFD2_k127_5092093_2 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000001778 248.0
HFD2_k127_5092093_3 Histidine kinase K13598 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000001972 259.0
HFD2_k127_5092093_4 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000005003 182.0
HFD2_k127_5092093_5 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000002164 182.0
HFD2_k127_5092093_6 Cold shock protein K03704 - - 0.000000000000000000000000002823 114.0
HFD2_k127_5149460_0 Bacterial Ig-like domain (group 3) K20276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008387 309.0
HFD2_k127_5149460_1 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000000000000009024 188.0
HFD2_k127_5149460_2 fibronectin type III domain protein - - - 0.0000000000000001268 95.0
HFD2_k127_5195922_0 Responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002811 373.0
HFD2_k127_5195922_1 Bacterial transcriptional repressor C-terminal K09017 - - 0.000000000000000000000000000000000000000000000000000001347 199.0
HFD2_k127_5195922_2 Biotin-lipoyl like K03543 - - 0.0000000000000000000000009824 113.0
HFD2_k127_5195922_3 modulator of DNA gyrase K03592 - - 0.000003562 60.0
HFD2_k127_5274798_0 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000000000000000000000000000000000000000001924 209.0
HFD2_k127_5274798_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000004375 210.0
HFD2_k127_5274798_2 C4-dicarboxylate ABC transporter permease - - - 0.00000000000000000000001888 100.0
HFD2_k127_5274798_3 - - - - 0.0000000000000000004101 100.0
HFD2_k127_5274798_4 - - - - 0.000000005064 68.0
HFD2_k127_5282008_0 Heat shock 70 kDa protein K04043 - - 1.183e-273 856.0
HFD2_k127_5282008_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007373 572.0
HFD2_k127_5282008_10 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000007881 126.0
HFD2_k127_5282008_11 PFAM Glycosyl transferase, group 1 - - - 0.000000002781 68.0
HFD2_k127_5282008_12 pectinesterase activity K10117 - - 0.0000002125 64.0
HFD2_k127_5282008_13 COG1404 Subtilisin-like serine proteases K14645 GO:0005575,GO:0005576 - 0.0003395 55.0
HFD2_k127_5282008_2 Pkd domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003825 417.0
HFD2_k127_5282008_3 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 385.0
HFD2_k127_5282008_4 PFAM Amidohydrolase 3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 345.0
HFD2_k127_5282008_5 alginic acid biosynthetic process K07218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007676 318.0
HFD2_k127_5282008_6 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000001674 223.0
HFD2_k127_5282008_7 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000001334 211.0
HFD2_k127_5282008_8 RNA polymerase sigma factor K03088 - - 0.00000000000000000000000000000000000002678 151.0
HFD2_k127_5282008_9 radical SAM domain protein - - - 0.0000000000000000000000000000002381 124.0
HFD2_k127_5284607_0 PFAM Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005321 425.0
HFD2_k127_5284607_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007628 364.0
HFD2_k127_5284607_10 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000006734 115.0
HFD2_k127_5284607_11 Could be involved in septation K06412 - - 0.0000000000000000000001271 104.0
HFD2_k127_5284607_12 Single-strand binding protein family K03111 - - 0.000000000000000000002994 100.0
HFD2_k127_5284607_13 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000002881 99.0
HFD2_k127_5284607_14 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000002236 87.0
HFD2_k127_5284607_15 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.0000000000004989 82.0
HFD2_k127_5284607_16 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.00000002895 66.0
HFD2_k127_5284607_17 TIGRFAM TonB K03832 - - 0.000003821 57.0
HFD2_k127_5284607_2 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005054 286.0
HFD2_k127_5284607_3 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000004055 250.0
HFD2_k127_5284607_4 UbiA prenyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000001525 239.0
HFD2_k127_5284607_5 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000003601 198.0
HFD2_k127_5284607_6 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000001482 166.0
HFD2_k127_5284607_7 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000127 157.0
HFD2_k127_5284607_8 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000001959 138.0
HFD2_k127_5284607_9 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0040007,GO:0044237,GO:0050515 2.7.1.148 0.00000000000000000000000000000001761 146.0
HFD2_k127_5294050_0 His Kinase A (phosphoacceptor) domain - - - 0.0 2213.0
HFD2_k127_5294050_1 two-component system sensor protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 475.0
HFD2_k127_5347343_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008054 522.0
HFD2_k127_5347343_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 440.0
HFD2_k127_5347343_10 Cell division protein FtsQ K03589 - - 0.00006846 54.0
HFD2_k127_5347343_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009154 442.0
HFD2_k127_5347343_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0051258,GO:0051301,GO:0065003,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 398.0
HFD2_k127_5347343_4 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008764,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 371.0
HFD2_k127_5347343_5 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007205 297.0
HFD2_k127_5347343_6 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000007249 282.0
HFD2_k127_5347343_7 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002856 286.0
HFD2_k127_5347343_8 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000001275 94.0
HFD2_k127_5347343_9 Tetratricopeptide repeat - - - 0.000004213 55.0
HFD2_k127_5377799_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 1.03e-295 934.0
HFD2_k127_5377799_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 GO:0002682,GO:0002684,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006950,GO:0008150,GO:0009314,GO:0009380,GO:0009605,GO:0009607,GO:0009628,GO:0016020,GO:0032991,GO:0035821,GO:0042802,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 2.239e-256 814.0
HFD2_k127_5377799_2 peptidase K01415,K07386 - 3.4.24.71 3.575e-209 669.0
HFD2_k127_5377799_3 Peptidase family M13 K07386 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 617.0
HFD2_k127_5377799_4 Glyoxalase bleomycin resistance protein dioxygenase K15975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 395.0
HFD2_k127_5377799_5 Domain of unknown function (DUF4139) - - - 0.00000000000000000000000000000000000000000000002506 187.0
HFD2_k127_5377799_6 Protein of unknown function (DUF1697) - - - 0.00000000000000000000000000000000000000000005312 166.0
HFD2_k127_5377799_7 endonuclease activity K07451 - - 0.0000000000000004117 87.0
HFD2_k127_5377799_8 chlorophyll binding K03651,K03771,K07017 - 3.1.4.53,5.2.1.8 0.0000000003758 73.0
HFD2_k127_5377799_9 translation initiation factor activity - - - 0.00006824 55.0
HFD2_k127_5384817_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1625.0
HFD2_k127_5384817_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 424.0
HFD2_k127_5384817_2 ATPase with chaperone activity K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007493 342.0
HFD2_k127_5384817_3 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 322.0
HFD2_k127_5384817_4 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000004418 255.0
HFD2_k127_5384817_5 Domain of unknown function (DUF4440) - - - 0.00000000000000000000000002885 119.0
HFD2_k127_5384817_6 endonuclease activity K07451 - - 0.0000000005772 64.0
HFD2_k127_5384817_7 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0020012,GO:0030682,GO:0042221,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0051920,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0070887,GO:0075136,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.0000002031 60.0
HFD2_k127_5390766_0 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0 1296.0
HFD2_k127_5390766_1 WD40 domain protein beta Propeller K12132 - 2.7.11.1 6.28e-230 740.0
HFD2_k127_5390766_10 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K20940 - 1.14.13.218 0.000000000000000000000000000000000000000000005503 169.0
HFD2_k127_5390766_11 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000004608 65.0
HFD2_k127_5390766_12 Evidence 5 No homology to any previously reported sequences - - - 0.000000002971 70.0
HFD2_k127_5390766_13 Sigma-70, region 4 - - - 0.0000178 55.0
HFD2_k127_5390766_14 Tetratricopeptide repeat - - - 0.0007993 52.0
HFD2_k127_5390766_15 Copper binding proteins, plastocyanin/azurin family - - - 0.0008605 49.0
HFD2_k127_5390766_2 FAD dependent oxidoreductase - - - 3.496e-205 652.0
HFD2_k127_5390766_3 Protein of unknown function (DUF3494) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009471 600.0
HFD2_k127_5390766_4 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006936 482.0
HFD2_k127_5390766_5 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009046 422.0
HFD2_k127_5390766_6 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006499 332.0
HFD2_k127_5390766_7 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000000000000000000000000000000002324 231.0
HFD2_k127_5390766_8 Belongs to the Dps family K04047 - - 0.000000000000000000000000000000000000000000000000000486 191.0
HFD2_k127_5390766_9 response regulator K07782 - - 0.0000000000000000000000000000000000000000000000689 180.0
HFD2_k127_5395254_0 Thioesterase involved in non-ribosomal peptide biosynthesis - - - 0.0 1203.0
HFD2_k127_5395254_1 Phosphopantetheine attachment site - - - 6.776e-318 993.0
HFD2_k127_5395254_10 Protein of unknown function (DUF2723) - - - 0.00001197 58.0
HFD2_k127_5395254_2 Ornithine cyclodeaminase K01750 - 4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000036 576.0
HFD2_k127_5395254_3 cysteine biosynthetic process from serine K21949 - 2.5.1.140 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007317 519.0
HFD2_k127_5395254_4 response to abiotic stimulus K03086,K06867 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 497.0
HFD2_k127_5395254_5 taurine catabolism dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 479.0
HFD2_k127_5395254_6 4'-phosphopantetheinyl transferase superfamily K06133 - - 0.0000000000000000000000000000000000000000000000000000000000000002462 253.0
HFD2_k127_5395254_7 Haemolysin-III related K11068 - - 0.00000000000000000000000000000000000000000000000000000000629 210.0
HFD2_k127_5395254_8 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000007027 184.0
HFD2_k127_5395254_9 transcriptional regulator - - - 0.000000000000000000000000000006951 124.0
HFD2_k127_5406683_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 6.626e-286 895.0
HFD2_k127_5406683_1 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000001369 246.0
HFD2_k127_5406683_2 ABC transporter transmembrane region K06147 - - 0.000000000000000000000000000000000000000000000000000000000002258 235.0
HFD2_k127_5406683_3 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000007591 235.0
HFD2_k127_5406683_4 SprB repeat - - - 0.000000002243 71.0
HFD2_k127_5407094_0 ligase activity, forming nitrogen-metal bonds K02230 - 6.6.1.2 0.0 1337.0
HFD2_k127_5407094_1 Nucleoside recognition - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003899 478.0
HFD2_k127_5407094_2 PFAM NADH Ubiquinone plastoquinone (complex I) K12137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009018 456.0
HFD2_k127_5407094_3 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004839 317.0
HFD2_k127_5407094_4 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.00000000000000000000000000000000000000000000000000003016 195.0
HFD2_k127_5407094_5 hydrogenase 4 membrane K12140 - - 0.0000000000000000000000000000002139 140.0
HFD2_k127_5407094_6 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000005136 121.0
HFD2_k127_5410034_0 Glycosyltransferase like family 2 - - - 1.032e-266 862.0
HFD2_k127_5410034_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K15372 - 2.6.1.55 3.548e-220 690.0
HFD2_k127_5410034_10 Domain of unknown function (DUF4386) - - - 0.0000000000000000000000000006728 123.0
HFD2_k127_5410034_11 PFAM blue (type 1) copper domain protein - - - 0.000000000000005789 82.0
HFD2_k127_5410034_12 Thioredoxin-like - - - 0.00000002581 67.0
HFD2_k127_5410034_13 Beta-lactamase - - - 0.00000009073 64.0
HFD2_k127_5410034_14 Fibronectin type 3 domain - - - 0.00002391 58.0
HFD2_k127_5410034_15 Peptidase family C25 - - - 0.00002821 59.0
HFD2_k127_5410034_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008012 591.0
HFD2_k127_5410034_3 3-beta hydroxysteroid dehydrogenase/isomerase family K08678 - 4.1.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 493.0
HFD2_k127_5410034_4 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784,K12448 - 5.1.3.2,5.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 410.0
HFD2_k127_5410034_6 Phosphoenolpyruvate phosphomutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 319.0
HFD2_k127_5410034_7 N-acetylglucosaminylinositol deacetylase activity K22135 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001917 274.0
HFD2_k127_5410034_9 peptidyl-tyrosine sulfation K13992 - - 0.000000000000000000000000000000000000000001125 172.0
HFD2_k127_5423911_0 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K03520 - 1.2.5.3 8.059e-305 959.0
HFD2_k127_5423911_1 Fructose-bisphosphate aldolase class-II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 471.0
HFD2_k127_5423911_10 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000000002206 235.0
HFD2_k127_5423911_11 FAD dependent oxidoreductase K09471 - - 0.000000000000000000000000000000000000000000000000000163 202.0
HFD2_k127_5423911_12 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000001072 187.0
HFD2_k127_5423911_13 HNH nucleases - - - 0.0000000000000000000000002237 118.0
HFD2_k127_5423911_14 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000001823 110.0
HFD2_k127_5423911_15 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.00000000000006125 81.0
HFD2_k127_5423911_2 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003575 467.0
HFD2_k127_5423911_3 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 441.0
HFD2_k127_5423911_4 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 422.0
HFD2_k127_5423911_5 Aminotransferase class-V K01556 - 3.7.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 367.0
HFD2_k127_5423911_6 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007436 301.0
HFD2_k127_5423911_7 Major Facilitator Superfamily K02445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 306.0
HFD2_k127_5423911_8 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008176 294.0
HFD2_k127_5423911_9 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000005165 248.0
HFD2_k127_5433409_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1142.0
HFD2_k127_5433409_1 MutL protein - - - 6.749e-235 746.0
HFD2_k127_5433409_10 COGs COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009316 273.0
HFD2_k127_5433409_11 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001407 257.0
HFD2_k127_5433409_12 MotA/TolQ/ExbB proton channel family K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000004615 228.0
HFD2_k127_5433409_13 Glycine cleavage H-protein K02437 - - 0.00000000000000000000000000000000000000000008833 163.0
HFD2_k127_5433409_14 PFAM Biopolymer transport protein ExbD TolR - - - 0.0000000000000000000000000000411 122.0
HFD2_k127_5433409_15 biopolymer transport protein - - - 0.0000000000000000000000000002602 119.0
HFD2_k127_5433409_16 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000000000000000000000000002712 125.0
HFD2_k127_5433409_17 STAS domain K04749 - - 0.00000000000000002405 87.0
HFD2_k127_5433409_18 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000000000001814 76.0
HFD2_k127_5433409_19 Tetratricopeptide repeat - - - 0.0000000002179 74.0
HFD2_k127_5433409_2 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000521 583.0
HFD2_k127_5433409_20 PFAM outer membrane efflux protein - - - 0.000000001377 72.0
HFD2_k127_5433409_21 - - - - 0.000000004475 63.0
HFD2_k127_5433409_22 PBP superfamily domain K02040 - - 0.0009201 45.0
HFD2_k127_5433409_3 L-threonine 3-dehydrogenase K00060 - 1.1.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 376.0
HFD2_k127_5433409_4 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008983 376.0
HFD2_k127_5433409_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 362.0
HFD2_k127_5433409_6 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 325.0
HFD2_k127_5433409_7 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000918 334.0
HFD2_k127_5433409_8 COGs COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009988 314.0
HFD2_k127_5433409_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001806 287.0
HFD2_k127_5450045_0 KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.0000000000000000000000000000000000003812 147.0
HFD2_k127_5464656_0 Domain of unknown function (DUF5117) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006752 616.0
HFD2_k127_5464656_1 Involved in the TonB-independent uptake of proteins K03641 - - 0.00000000000000000002303 102.0
HFD2_k127_5475861_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 492.0
HFD2_k127_5475861_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004908 259.0
HFD2_k127_5482163_0 GlcNAc-PI de-N-acetylase - - - 1.94e-206 659.0
HFD2_k127_5482163_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.00000000000000000000000000000000000000005987 159.0
HFD2_k127_5501884_0 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 5.118e-217 684.0
HFD2_k127_5501884_1 Belongs to the peptidase M16 family K07263 - - 1.902e-206 676.0
HFD2_k127_5501884_2 [isocitrate dehydrogenase (NADP+)] phosphatase activity K00906 GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004721,GO:0004722,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009060,GO:0009987,GO:0015980,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0016999,GO:0017076,GO:0017144,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046487,GO:0050790,GO:0055114,GO:0065007,GO:0065009,GO:0070262,GO:0071704,GO:0072350,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006874 557.0
HFD2_k127_5501884_3 succinyl-diaminopimelate desuccinylase activity K01295 - 3.4.17.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 495.0
HFD2_k127_5501884_4 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000001396 124.0
HFD2_k127_5501884_5 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000002202 107.0
HFD2_k127_5501884_6 Tetratricopeptide repeat - - - 0.000000001102 68.0
HFD2_k127_5504842_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 568.0
HFD2_k127_5504842_1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005291 519.0
HFD2_k127_5504842_2 Aminotransferase class-V K04127 - 5.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008516 471.0
HFD2_k127_5504842_3 PFAM NADH Ubiquinone plastoquinone (complex I) K12141 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008937 393.0
HFD2_k127_5504842_4 Evidence 5 No homology to any previously reported sequences K07004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004722 320.0
HFD2_k127_5504842_5 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008327 286.0
HFD2_k127_5504842_6 thiolester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000008511 218.0
HFD2_k127_5504842_7 hydrogenase 4 membrane K12140 - - 0.000000004588 57.0
HFD2_k127_552822_0 COG0488 ATPase components of ABC transporters with duplicated ATPase domains - - - 2.623e-253 793.0
HFD2_k127_552822_1 Belongs to the MurCDEF family - - - 2.56e-242 765.0
HFD2_k127_552822_10 Histidine kinase - - - 0.000000000000000000000000000000000000000001729 171.0
HFD2_k127_552822_11 Serine phosphatase RsbU regulator of sigma subunit K07315 - 3.1.3.3 0.000000000000000000000000000000008304 141.0
HFD2_k127_552822_12 Response regulator receiver domain - - - 0.0000000000000000000000000003181 130.0
HFD2_k127_552822_13 Protein of unknown function (DUF423) - - - 0.0000000000000000000000004747 108.0
HFD2_k127_552822_14 PFAM Iron sulphur-containing domain, CDGSH-type - - - 0.00000000000000000000007094 100.0
HFD2_k127_552822_15 SURF1 family K14998 - - 0.0000000000000000001848 100.0
HFD2_k127_552822_16 Cell wall-active antibiotics response 4TMS YvqF - - - 0.00000000000000002337 90.0
HFD2_k127_552822_17 membrane - - - 0.000007772 53.0
HFD2_k127_552822_18 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K07752 - 3.4.17.18,3.4.17.22 0.00001103 59.0
HFD2_k127_552822_2 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 567.0
HFD2_k127_552822_3 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 414.0
HFD2_k127_552822_4 beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003114 376.0
HFD2_k127_552822_6 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000000000000003642 204.0
HFD2_k127_552822_7 Protein of unknown function (DUF998) - - - 0.000000000000000000000000000000000000000000000000006913 201.0
HFD2_k127_552822_8 - - - - 0.00000000000000000000000000000000000000000005257 169.0
HFD2_k127_552822_9 NAD dependent epimerase/dehydratase family - - - 0.0000000000000000000000000000000000000000001255 172.0
HFD2_k127_5539557_0 Thermolysin metallopeptidase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004236 386.0
HFD2_k127_5539557_1 Cytochrome C and Quinol oxidase polypeptide I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004282 326.0
HFD2_k127_5539557_10 molybdopterin K03750 - 2.10.1.1 0.000000000000000000000000000000000003766 142.0
HFD2_k127_5539557_11 - - - - 0.0000002636 56.0
HFD2_k127_5539557_13 - - - - 0.000005234 56.0
HFD2_k127_5539557_14 Anti-sigma-K factor RskA - - - 0.00000569 59.0
HFD2_k127_5539557_2 HupE / UreJ protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001645 251.0
HFD2_k127_5539557_3 Cytochrome C oxidase subunit II, periplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002871 235.0
HFD2_k127_5539557_4 Major facilitator Superfamily K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000003006 237.0
HFD2_k127_5539557_5 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000000000001645 198.0
HFD2_k127_5539557_6 Domain of unknown function (DUF4198) - - - 0.0000000000000000000000000000000000000000000000000003526 199.0
HFD2_k127_5539557_7 Cytochrome c - - - 0.000000000000000000000000000000000000000000000009762 180.0
HFD2_k127_5539557_8 Transcriptional regulator - - - 0.000000000000000000000000000000000000001146 150.0
HFD2_k127_5539557_9 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000001374 147.0
HFD2_k127_5540144_0 Uncharacterized protein conserved in bacteria (DUF2330) K00347,K21163 GO:0000166,GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008144,GO:0008150,GO:0008152,GO:0010181,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0019842,GO:0030001,GO:0030964,GO:0032553,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044425,GO:0044464,GO:0048037,GO:0050136,GO:0050662,GO:0051179,GO:0051234,GO:0055114,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:1901265,GO:1901363,GO:1902444,GO:1902494 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 434.0
HFD2_k127_5540144_1 Metallopeptidase family M24 K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001241 275.0
HFD2_k127_5540144_2 Thrombospondin type 3 repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001468 270.0
HFD2_k127_5540144_3 Belongs to the NqrB RnfD family - - - 0.00000000000000000000000000000000000000000000000000005959 201.0
HFD2_k127_5540144_4 Glycosyltransferase family 87 K13671 - - 0.00005191 55.0
HFD2_k127_5555369_0 cellulase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 559.0
HFD2_k127_5555369_1 Lipase maturation factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 494.0
HFD2_k127_5555369_2 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 375.0
HFD2_k127_5555369_3 Winged helix DNA-binding domain K09927 - - 0.00000000000000000000000000000000000000000000000000000000001569 222.0
HFD2_k127_5555369_4 regulation of translation K03530 - - 0.000000000000000000000000000006309 123.0
HFD2_k127_5555369_5 Protein of unknown function (DUF3052) - - - 0.0000000276 66.0
HFD2_k127_5589446_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 626.0
HFD2_k127_5589446_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 454.0
HFD2_k127_5589446_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 385.0
HFD2_k127_5589446_3 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008157 295.0
HFD2_k127_5589446_4 Belongs to the DNA glycosylase MPG family K03652 GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 0.00000000000000000000000000000000000000000000277 173.0
HFD2_k127_5589446_5 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000008272 148.0
HFD2_k127_5589446_6 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.0000000000000000000000004508 115.0
HFD2_k127_5589446_7 Tetratricopeptide repeat - - - 0.00002985 57.0
HFD2_k127_5589446_8 - - - - 0.00003504 55.0
HFD2_k127_5607862_0 acyl-CoA transferases carnitine dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005031 431.0
HFD2_k127_5607862_1 - - - - 0.0000000000009302 80.0
HFD2_k127_5671638_0 Glycosyl transferase family 2 K11936,K14666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 365.0
HFD2_k127_5671638_1 WD40-like Beta Propeller Repeat K03641 - - 0.000000000000000000000000000000000000000000007042 179.0
HFD2_k127_5671638_2 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000000001133 149.0
HFD2_k127_5671638_3 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000009524 148.0
HFD2_k127_5671638_4 metallopeptidase activity K01186 - 3.2.1.18 0.0000000000005523 81.0
HFD2_k127_5671638_5 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000001123 67.0
HFD2_k127_5671638_6 arabinogalactan endo-1,4-beta-galactosidase activity - - - 0.0001139 54.0
HFD2_k127_5671638_7 pectinesterase activity K10117 - - 0.0003087 53.0
HFD2_k127_5686443_0 Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor K00697 - 2.4.1.15,2.4.1.347 1.437e-311 970.0
HFD2_k127_5686443_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006408 600.0
HFD2_k127_5686443_2 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 292.0
HFD2_k127_5686443_3 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006021 244.0
HFD2_k127_5686443_4 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.0000000000000000000000000000000000000000000000000000000002927 233.0
HFD2_k127_5686443_5 PFAM Glycoside hydrolase 15-related - - - 0.00000000000000000000000000000000000000000000000000000002097 214.0
HFD2_k127_5686443_6 - - - - 0.00000000000002974 80.0
HFD2_k127_5686443_7 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000006507 74.0
HFD2_k127_5730257_0 ABC-type multidrug transport system ATPase and permease K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 598.0
HFD2_k127_5730257_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000002733 231.0
HFD2_k127_5785465_0 Transglycosylase K05366 GO:0003674,GO:0005488,GO:0005515,GO:0042802 2.4.1.129,3.4.16.4 7.615e-196 635.0
HFD2_k127_5785465_1 PFAM Arsenical pump membrane protein K03893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 317.0
HFD2_k127_5785465_2 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000001398 237.0
HFD2_k127_5785465_3 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000006798 72.0
HFD2_k127_5789196_0 L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp K01876 - 6.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004418 386.0
HFD2_k127_5789196_1 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004362 345.0
HFD2_k127_5789196_2 Nuclease, EndA NucM family - - - 0.00000000000000000000000000000000000000000000000000000000000000000004916 259.0
HFD2_k127_5789196_3 cellulase activity - - - 0.00000000000000000000000000000000000000000000002207 194.0
HFD2_k127_5789196_4 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.000000000000000000000000000000000002567 148.0
HFD2_k127_5789196_5 - - - - 0.00000000000000000000000000005478 132.0
HFD2_k127_5789196_6 - - - - 0.0000000000000009501 83.0
HFD2_k127_5810004_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 5.513e-250 781.0
HFD2_k127_5810004_1 response regulator K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000002371 222.0
HFD2_k127_5810004_2 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000004041 141.0
HFD2_k127_5810004_3 Protein of unknown function, DUF255 - - - 0.000000000000000000000000000000001441 134.0
HFD2_k127_5810004_4 EXOIII K02342 - 2.7.7.7 0.000000000000000000000000000000306 130.0
HFD2_k127_5810004_5 Redoxin K03386 - 1.11.1.15 0.000000000000000000000000004561 118.0
HFD2_k127_582696_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 1.105e-314 1008.0
HFD2_k127_582696_1 Acyl-CoA dehydrogenase, middle domain - GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 1.24e-207 666.0
HFD2_k127_582696_2 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004865 311.0
HFD2_k127_582696_3 Belongs to the peptidase S8 family K17734 - - 0.0000000000000000000000000000000000000000000000000000000000000002489 244.0
HFD2_k127_582696_4 Glycosyl transferase, family 2 K01002,K20534 - 2.7.8.20 0.00000000000000000000000000000000000000000001536 184.0
HFD2_k127_582696_5 peptidase - - - 0.000000000000000000000000000000000003041 158.0
HFD2_k127_5843955_0 Peptidase family M1 domain K01992 - - 3.321e-236 759.0
HFD2_k127_5843955_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000768 269.0
HFD2_k127_5843955_2 Prolyl oligopeptidase, N-terminal beta-propeller domain - - - 0.0000000000000000000000000000000000000000000488 164.0
HFD2_k127_5843955_3 FlgD Ig-like domain - - - 0.000000000000000001289 103.0
HFD2_k127_5843955_4 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.0008084 54.0
HFD2_k127_5864305_0 aldehyde-lyase activity K01621 - 4.1.2.22,4.1.2.9 0.0 1185.0
HFD2_k127_5864305_1 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 499.0
HFD2_k127_5864305_10 Protein of unknown function (DUF2953) - - - 0.00001172 55.0
HFD2_k127_5864305_2 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 401.0
HFD2_k127_5864305_3 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005969 361.0
HFD2_k127_5864305_4 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005675 333.0
HFD2_k127_5864305_5 Protein of unknown function (DUF1207) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001563 283.0
HFD2_k127_5864305_6 Phosphoglycerate mutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001137 266.0
HFD2_k127_5864305_7 Sporulation protein YtfJ (Spore_YtfJ) - - - 0.0000000000000000000000000000002217 127.0
HFD2_k127_5864305_8 - - - - 0.00000000000000000000000000001807 124.0
HFD2_k127_5864305_9 - - - - 0.0000000000001314 79.0
HFD2_k127_5903663_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 500.0
HFD2_k127_5903663_1 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000008296 120.0
HFD2_k127_5903663_2 Glycogen recognition site of AMP-activated protein kinase - - - 0.00000000000000000006836 92.0
HFD2_k127_5903663_3 - - - - 0.0000000000000001981 90.0
HFD2_k127_5903663_4 - - - - 0.00000000000001425 87.0
HFD2_k127_5966119_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 342.0
HFD2_k127_5966119_1 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 304.0
HFD2_k127_5966119_10 PFAM Methyltransferase type 11 - - - 0.0000000000000006303 91.0
HFD2_k127_5966119_11 M6 family metalloprotease domain protein - - - 0.000005192 58.0
HFD2_k127_5966119_2 CBS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004107 287.0
HFD2_k127_5966119_3 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007921 250.0
HFD2_k127_5966119_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000002564 252.0
HFD2_k127_5966119_5 PFAM ADP-ribosylation factor family K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000004564 233.0
HFD2_k127_5966119_6 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000007517 157.0
HFD2_k127_5966119_7 Roadblock/LC7 domain - - - 0.0000000000000000000000283 117.0
HFD2_k127_5966119_8 PFAM phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.0000000000000000001518 99.0
HFD2_k127_5966119_9 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000004641 93.0
HFD2_k127_603091_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 1.32e-228 717.0
HFD2_k127_603091_1 PFAM ABC-1 domain protein K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 456.0
HFD2_k127_603091_2 M1 (1,4-beta-N-acetylmuramidase) K07273 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001024 284.0
HFD2_k127_603091_3 deacetylase - - - 0.00000000000000000000000000000003078 140.0
HFD2_k127_603091_4 PFAM Glycosyl transferase family 2 - - - 0.000000000000000082 93.0
HFD2_k127_603091_5 Phosphate acyltransferases K13507 - 2.3.1.15,2.3.1.42 0.000000000000000155 93.0
HFD2_k127_603091_6 ribosomal large subunit export from nucleus - - - 0.000002929 60.0
HFD2_k127_6037212_0 cell adhesion involved in biofilm formation K13735 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 526.0
HFD2_k127_6037212_1 CheB methylesterase K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000005739 277.0
HFD2_k127_6037212_2 Evidence 2b Function of strongly homologous gene K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000007705 259.0
HFD2_k127_6037212_3 PFAM MCP methyltransferase CheR-type K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000009393 243.0
HFD2_k127_6037212_4 Chemotaxis sensory transducer K03406 - - 0.00000000000000000000000000000000008485 155.0
HFD2_k127_6037212_5 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000002648 124.0
HFD2_k127_6037212_6 Domain of unknown function DUF11 - - - 0.0000000000000000000007499 103.0
HFD2_k127_6037212_7 Two component signalling adaptor domain K03408 - - 0.00003438 51.0
HFD2_k127_6049234_0 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087,K16055 GO:0003674,GO:0003824,GO:0004805,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0033554,GO:0034637,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044464,GO:0046351,GO:0050896,GO:0051716,GO:0070413,GO:0071704,GO:1901576 2.4.1.15,3.1.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000006145 270.0
HFD2_k127_6049234_1 CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000002715 111.0
HFD2_k127_6049234_2 Tetratricopeptide repeat - - - 0.00000001838 65.0
HFD2_k127_6072969_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00850,K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 492.0
HFD2_k127_6072969_1 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000000000000000000000000000000005776 170.0
HFD2_k127_6072969_2 cellulose binding - - - 0.0000000000000000000002968 115.0
HFD2_k127_6072969_3 Belongs to the peptidase S8 family K12287 - - 0.00000000000001687 89.0
HFD2_k127_6072969_4 alginic acid biosynthetic process K01729 - 4.2.2.3 0.000000008956 70.0
HFD2_k127_6072969_5 dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000005236 62.0
HFD2_k127_6072969_6 Belongs to the peptidase S8 family - - - 0.000002861 62.0
HFD2_k127_6074794_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009286 586.0
HFD2_k127_6074794_1 two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 404.0
HFD2_k127_6074794_10 cytochrome oxidase assembly K02259 - - 0.000000000000001063 83.0
HFD2_k127_6074794_11 OmpA family K03286 - - 0.000000000002832 79.0
HFD2_k127_6074794_12 - - - - 0.00000001733 61.0
HFD2_k127_6074794_13 helix_turn_helix, Arsenical Resistance Operon Repressor K22042 GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000007139 61.0
HFD2_k127_6074794_14 surface antigen K07001 - - 0.0000001163 66.0
HFD2_k127_6074794_15 Polymer-forming cytoskeletal - - - 0.00002362 56.0
HFD2_k127_6074794_16 - - - - 0.0001822 52.0
HFD2_k127_6074794_17 Putative zinc-finger - - - 0.000293 51.0
HFD2_k127_6074794_2 Bacterial regulatory protein, Fis family K02584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 314.0
HFD2_k127_6074794_3 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004608 288.0
HFD2_k127_6074794_4 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000007923 254.0
HFD2_k127_6074794_5 cellulase activity K06882 - - 0.000000000000000000000000000000000000000000000000000000894 205.0
HFD2_k127_6074794_6 Histidine kinase K13598 - 2.7.13.3 0.00000000000000000000000000000000000000000001472 180.0
HFD2_k127_6074794_7 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000004983 166.0
HFD2_k127_6074794_8 ECF sigma factor K03088 - - 0.0000000000000000000000000000000000000001798 156.0
HFD2_k127_6074794_9 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000008988 160.0
HFD2_k127_6148906_0 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004146 411.0
HFD2_k127_6148906_1 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000771 389.0
HFD2_k127_6148906_2 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 388.0
HFD2_k127_6148906_3 Branched-chain amino acid transport system / permease component K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009019 369.0
HFD2_k127_6148906_4 ABC transporter, ATP-binding protein K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008329 320.0
HFD2_k127_6148906_5 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007633 316.0
HFD2_k127_6148906_6 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.00000000000000000000000001078 126.0
HFD2_k127_6148906_7 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000002993 91.0
HFD2_k127_6148906_8 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000000000003737 90.0
HFD2_k127_6148906_9 Required for chromosome condensation and partitioning K03529 - - 0.000000000000002057 81.0
HFD2_k127_6160754_0 GlcNAc-PI de-N-acetylase - - - 2.05e-264 834.0
HFD2_k127_6160754_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.0000000000005587 76.0
HFD2_k127_6187439_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 529.0
HFD2_k127_6187439_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009339 509.0
HFD2_k127_6187439_2 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.000000000000000000000000000000000000000000000000000003809 217.0
HFD2_k127_6187439_3 ABC-type transport system involved in lipoprotein release permease component K02004,K09808 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008104,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0034613,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0098796,GO:0098797,GO:1990778 - 0.0000002268 64.0
HFD2_k127_6191416_0 Methionine synthase B12-binding module cap domain protein K00548,K15023 - 2.1.1.13,2.1.1.258 0.0 1245.0
HFD2_k127_6191416_1 iron assimilation - - - 3.951e-231 721.0
HFD2_k127_6191416_2 Putative MetA-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 377.0
HFD2_k127_6191416_3 Pfam:Pyridox_oxidase K07006 - - 0.0000000000000000000000000000000000000000000000000000000000005101 224.0
HFD2_k127_6191416_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000001737 211.0
HFD2_k127_6191416_5 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000388 199.0
HFD2_k127_6191416_6 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000005947 129.0
HFD2_k127_6191416_7 acetyltransferases and hydrolases with the alpha beta hydrolase fold K01046 - 3.1.1.3 0.0000008757 63.0
HFD2_k127_6235402_0 xanthine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 447.0
HFD2_k127_6243822_0 Aldehyde dehydrogenase family K04021,K13922 GO:0003674,GO:0003824,GO:0004029,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 490.0
HFD2_k127_6243822_1 BMC - - - 0.00000000000000000000000000000342 138.0
HFD2_k127_6243822_2 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530,K05788 - - 0.000000000000000000000006089 109.0
HFD2_k127_6243822_3 Ethanolamine utilisation protein EutN/carboxysome - - - 0.0000000000000000000006487 98.0
HFD2_k127_6243822_4 Putative regulatory protein - - - 0.00000000004256 66.0
HFD2_k127_6243822_5 Ethanolamine utilisation protein EutN/carboxysome K04028 GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - 0.000000001104 69.0
HFD2_k127_6243822_6 PFAM Ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.000000001134 69.0
HFD2_k127_6243822_7 COGs COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein K04027,K04028 GO:0003674,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0031469,GO:0031471,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464 - 0.00000000461 58.0
HFD2_k127_6264270_0 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.00000000000000000000000000000000001168 148.0
HFD2_k127_6264270_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000005543 91.0
HFD2_k127_6278610_0 lysine biosynthetic process via aminoadipic acid - - - 1.118e-197 662.0
HFD2_k127_6278610_1 COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and K03182 - 4.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006194 580.0
HFD2_k127_6278610_10 pfkB family carbohydrate kinase - - - 0.00000000000000000000001036 113.0
HFD2_k127_6278610_11 BtpA family K06971 - - 0.0000000000000000005251 89.0
HFD2_k127_6278610_12 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000001827 59.0
HFD2_k127_6278610_13 cellulose binding - - - 0.000003957 60.0
HFD2_k127_6278610_14 peptidase activity, acting on L-amino acid peptides K07752 - 3.4.17.22 0.0007636 53.0
HFD2_k127_6278610_2 Beta-lactamase superfamily domain K06136 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 315.0
HFD2_k127_6278610_3 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006301 289.0
HFD2_k127_6278610_4 ABC transporter, transmembrane K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001643 253.0
HFD2_k127_6278610_5 Zgc 162297 K06971 - - 0.000000000000000000000000000000000000000000000000000002142 195.0
HFD2_k127_6278610_6 4-hydroxybenzoate polyprenyltransferase K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000001971 177.0
HFD2_k127_6278610_7 Glyoxal oxidase N-terminus - - - 0.0000000000000000000000000000000000000003925 172.0
HFD2_k127_6278610_8 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000002029 154.0
HFD2_k127_6278610_9 receptor K02014 - - 0.00000000000000000000000000303 130.0
HFD2_k127_6376398_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009515 321.0
HFD2_k127_6376398_1 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000001001 209.0
HFD2_k127_6376398_2 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000006044 141.0
HFD2_k127_6376398_3 Multicopper oxidase K00368 - 1.7.2.1 0.00000000002738 67.0
HFD2_k127_6381259_0 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000002917 180.0
HFD2_k127_6381259_1 Protein of unknown function (DUF979) - - - 0.000000000000000000000000000000000000003644 147.0
HFD2_k127_6381259_2 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000001835 141.0
HFD2_k127_6381259_3 gluconolactonase activity K01053 - 3.1.1.17 0.000000000000000000000000000000002701 131.0
HFD2_k127_6398904_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006775 501.0
HFD2_k127_6398904_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005356 302.0
HFD2_k127_6398904_2 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005471 272.0
HFD2_k127_6398904_3 Metal dependent phosphohydrolases with conserved 'HD' motif. K09163 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006977 265.0
HFD2_k127_6398904_4 Domains GAF, HisKA, HATPase_c, GAF, HD-GYP-related - - - 0.0000000000000000000000000000000000000000000000000000000007849 228.0
HFD2_k127_6398904_5 PFAM response regulator receiver K02483,K07658,K07668 - - 0.000000000000000000000000000000000000001189 154.0
HFD2_k127_6398904_6 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.000000002038 59.0
HFD2_k127_6398904_7 Tetratricopeptide TPR_2 repeat protein - - - 0.000008293 58.0
HFD2_k127_6467482_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 5.041e-225 730.0
HFD2_k127_6467482_1 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006809 612.0
HFD2_k127_6467482_10 Domain of unknown function (DUF4126) - - - 0.00000000000005006 80.0
HFD2_k127_6467482_2 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 452.0
HFD2_k127_6467482_3 Pyrimidine nucleoside phosphorylase C-terminal domain K00756,K00758 - 2.4.2.2,2.4.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 377.0
HFD2_k127_6467482_4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775,K01929 - 5.1.1.1,6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 316.0
HFD2_k127_6467482_5 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001135 289.0
HFD2_k127_6467482_6 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000003701 183.0
HFD2_k127_6467482_7 TIGRFAM MazG family protein K02499,K04765 - 3.6.1.9 0.0000000000000000000000000000000000000004424 154.0
HFD2_k127_6467482_8 - - - - 0.000000000000000000000000000000000000768 145.0
HFD2_k127_6467482_9 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.000000000000000000000000000001232 138.0
HFD2_k127_6468845_0 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 576.0
HFD2_k127_6468845_1 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008267 508.0
HFD2_k127_6468845_10 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000000000000000000000000000003753 207.0
HFD2_k127_6468845_11 Belongs to the peptidase S8 family K08651,K14743 - 3.4.21.66 0.0000000000000000000000000000000000000000000001612 185.0
HFD2_k127_6468845_12 Cupin domain - - - 0.000000000000000000000000000000000000000000007573 162.0
HFD2_k127_6468845_13 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog - - - 0.0000000000000000000000000003033 123.0
HFD2_k127_6468845_14 CHAT domain - - - 0.000000000000000000002659 111.0
HFD2_k127_6468845_15 - - - - 0.000000000000148 73.0
HFD2_k127_6468845_16 cellulase activity K01179,K01361,K13277,K21449 - 3.2.1.4,3.4.21.96 0.0000003309 61.0
HFD2_k127_6468845_17 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 0.00001584 58.0
HFD2_k127_6468845_2 Sodium Bile acid symporter family K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007293 497.0
HFD2_k127_6468845_3 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006986 479.0
HFD2_k127_6468845_4 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004784 476.0
HFD2_k127_6468845_5 ABC transporter transmembrane region K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005482 499.0
HFD2_k127_6468845_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008321 407.0
HFD2_k127_6468845_7 glycosyl hydrolase, BNR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003219 379.0
HFD2_k127_6468845_8 Mo-molybdopterin cofactor biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000009395 246.0
HFD2_k127_6468845_9 - - - - 0.000000000000000000000000000000000000000000000000000000000003651 235.0
HFD2_k127_6484820_0 Protein of unknown function (DUF3604) - - - 0.0 1046.0
HFD2_k127_6484820_1 Glutamine amidotransferase domain - - - 3.209e-220 707.0
HFD2_k127_6484820_11 UreE urease accessory protein, C-terminal domain K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001881 280.0
HFD2_k127_6484820_12 COG0501 Zn-dependent protease with chaperone function - GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071586,GO:0071704,GO:0080120,GO:0140096,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001302 282.0
HFD2_k127_6484820_13 PPIC-type PPIASE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000003559 236.0
HFD2_k127_6484820_14 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000561 238.0
HFD2_k127_6484820_15 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000519 223.0
HFD2_k127_6484820_16 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000004991 177.0
HFD2_k127_6484820_17 Protein of unknown function (DUF1003) - - - 0.0000000000000000000000000000000000000000001467 171.0
HFD2_k127_6484820_18 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000000004775 157.0
HFD2_k127_6484820_19 Phosphoserine phosphatase K02203 - 2.7.1.39,3.1.3.3 0.0000000000000000000000000000000000000001861 162.0
HFD2_k127_6484820_2 Amino acid permease - - - 8.604e-201 644.0
HFD2_k127_6484820_20 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000002314 168.0
HFD2_k127_6484820_21 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000000000000004916 151.0
HFD2_k127_6484820_22 Beta-galactosidase - - - 0.00000000000000000000000000000007522 146.0
HFD2_k127_6484820_23 Peptidase family M23 - - - 0.00000000000000000000000000001234 137.0
HFD2_k127_6484820_24 helix_turn_helix ASNC type K03719 - - 0.00000000000000000000000000001601 123.0
HFD2_k127_6484820_25 - - - - 0.00000000000000000000000000002389 127.0
HFD2_k127_6484820_26 transposase activity K07483,K07497 - - 0.0000000000000000000000001635 111.0
HFD2_k127_6484820_27 - - - - 0.0000000000000000000001729 111.0
HFD2_k127_6484820_28 methyltransferase - - - 0.0000000000003887 80.0
HFD2_k127_6484820_29 PQQ-like domain K17713 - - 0.00000000001503 75.0
HFD2_k127_6484820_3 Major facilitator Superfamily - - - 1.209e-196 629.0
HFD2_k127_6484820_30 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0008152,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0016491,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0055114,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.000000003417 68.0
HFD2_k127_6484820_31 Integrase core domain K07497 - - 0.0000001172 59.0
HFD2_k127_6484820_32 WD domain, G-beta repeat - - - 0.000001171 62.0
HFD2_k127_6484820_33 Sulfatase K01130 - 3.1.6.1 0.0002327 53.0
HFD2_k127_6484820_4 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 572.0
HFD2_k127_6484820_5 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K03918 - 2.6.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000616 539.0
HFD2_k127_6484820_6 HupE / UreJ protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 359.0
HFD2_k127_6484820_7 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003913 334.0
HFD2_k127_6484820_8 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005152 289.0
HFD2_k127_6484820_9 L,D-transpeptidase catalytic domain K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004778 301.0
HFD2_k127_6517333_0 Glycosyl transferase family 21 K00752,K11936 - 2.4.1.212 0.0 1087.0
HFD2_k127_6517333_1 PFAM peptidase M13 K07386 - - 5.736e-252 797.0
HFD2_k127_6517333_10 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000001387 220.0
HFD2_k127_6517333_11 AntiSigma factor - - - 0.000000000000000000000000000000000000000000000000000248 194.0
HFD2_k127_6517333_12 Cupin domain - - - 0.0000000000000000000000000000000000000000000000006526 177.0
HFD2_k127_6517333_13 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000003775 177.0
HFD2_k127_6517333_14 Haem-binding domain - - - 0.00000000000000000000000000000000000000002839 158.0
HFD2_k127_6517333_15 luxR family - - - 0.00000000000000000000000000000000000000003241 160.0
HFD2_k127_6517333_16 - - - - 0.0000000000000000000000000000000000001304 164.0
HFD2_k127_6517333_17 YCII-related domain - - - 0.00000000000000000000000000000000002447 139.0
HFD2_k127_6517333_18 Serine threonine protein kinase K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000004164 139.0
HFD2_k127_6517333_2 Major facilitator Superfamily K08162,K08226,K16211 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 459.0
HFD2_k127_6517333_21 - - - - 0.00000000004558 75.0
HFD2_k127_6517333_22 Peptidase family M13 K07386 - - 0.0000000002203 61.0
HFD2_k127_6517333_23 Hemerythrin HHE cation binding domain - - - 0.00000004229 63.0
HFD2_k127_6517333_24 Putative MetA-pathway of phenol degradation - - - 0.000001842 59.0
HFD2_k127_6517333_25 Evidence 5 No homology to any previously reported sequences K03088 - - 0.000025 57.0
HFD2_k127_6517333_26 Bicaudal D-related protein K16756 - - 0.000527 53.0
HFD2_k127_6517333_27 Serine threonine protein kinase K12132 - 2.7.11.1 0.0007497 46.0
HFD2_k127_6517333_3 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 384.0
HFD2_k127_6517333_4 peptidase activity, acting on L-amino acid peptides K07004,K09955 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008263 370.0
HFD2_k127_6517333_5 Domain of Unknown Function (DUF1259) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 339.0
HFD2_k127_6517333_6 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003683 271.0
HFD2_k127_6517333_7 Protein of unknown function (DUF1211) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004537 259.0
HFD2_k127_6517333_8 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000002408 226.0
HFD2_k127_6517333_9 Drug metabolite transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000003297 235.0
HFD2_k127_6547696_0 Domain of unknown function (DUF1998) K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004627 532.0
HFD2_k127_6547696_1 - - - - 0.0000000001103 75.0
HFD2_k127_6563252_0 Amino acid adenylation domain - - - 0.0 1094.0
HFD2_k127_6563252_1 PFAM multicopper oxidase type K14588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005214 420.0
HFD2_k127_6563252_2 signal sequence binding K07152 - - 0.000000000000000000000000000000000000000000001985 172.0
HFD2_k127_6563252_3 Belongs to the peptidase S8 family K17734 - - 0.0000000000000000000000000000000000006226 163.0
HFD2_k127_6563252_4 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000004444 156.0
HFD2_k127_6563252_5 self proteolysis K04771 - 3.4.21.107 0.000000000000000000000000000000004238 150.0
HFD2_k127_6563252_6 Subtilase family - - - 0.000000000000000000000000007618 128.0
HFD2_k127_6563252_7 Belongs to the P-Pant transferase superfamily K06133 - - 0.0000000000001203 86.0
HFD2_k127_6589010_0 Peptidase dimerisation domain - - - 2.176e-254 792.0
HFD2_k127_6589010_1 doubled CXXCH - - - 2.775e-224 722.0
HFD2_k127_6589010_2 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006746 424.0
HFD2_k127_6589010_3 Protein involved in meta-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 349.0
HFD2_k127_6589010_4 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000001098 207.0
HFD2_k127_6589010_5 YceI-like domain - - - 0.0000000000000000000000000000000000000000000000001022 183.0
HFD2_k127_6589010_6 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000002733 126.0
HFD2_k127_6589010_7 Pfam AhpC TSA family - - - 0.0000000000000000000000009959 113.0
HFD2_k127_6589010_8 Domain of unknown function (DUF4386) - - - 0.00000000000000001459 86.0
HFD2_k127_6592473_0 TonB-dependent receptor - - - 1.315e-239 768.0
HFD2_k127_6610406_0 metal-dependent hydrolase with the TIM-barrel fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003907 506.0
HFD2_k127_6610406_1 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006602 389.0
HFD2_k127_6610406_2 WD-40 repeat - - - 0.00000000000000000000000000000002086 140.0
HFD2_k127_6610406_3 Sigma-70 region 2 K03088 - - 0.000000009063 66.0
HFD2_k127_6614630_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K02887,K03628 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 4.66e-203 642.0
HFD2_k127_6614630_1 (ABC) transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 402.0
HFD2_k127_6614630_10 - - - - 0.0007136 53.0
HFD2_k127_6614630_2 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008629 386.0
HFD2_k127_6614630_3 BadF/BadG/BcrA/BcrD ATPase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005318 318.0
HFD2_k127_6614630_4 Peptidase family M1 domain K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005819 273.0
HFD2_k127_6614630_5 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000005176 250.0
HFD2_k127_6614630_6 DinB family - - - 0.0000000000000000000000000000000000000000000000000000000000000000003195 234.0
HFD2_k127_6614630_7 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.000000000000000000000000000000000000000000000000000000002774 226.0
HFD2_k127_6614630_8 PAS fold - - - 0.00000000000000000000000000000000007447 149.0
HFD2_k127_6614630_9 PFAM YbbR family protein - - - 0.0000000000001208 85.0
HFD2_k127_6632569_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 377.0
HFD2_k127_6632569_1 Cobyrinic acid ac-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000004038 226.0
HFD2_k127_6632569_2 May be involved in recombinational repair of damaged DNA K03631,K13582 GO:0000724,GO:0000725,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009295,GO:0009314,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071944,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000007179 228.0
HFD2_k127_6632569_3 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000000000004796 194.0
HFD2_k127_6643611_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007281 501.0
HFD2_k127_6643611_1 nuclear chromosome segregation - - - 0.00000000000000000000000000001114 136.0
HFD2_k127_6643611_2 Belongs to the ompA family - - - 0.0000000000000000000000001618 110.0
HFD2_k127_6643611_3 Endonuclease I - - - 0.00002463 57.0
HFD2_k127_6650282_0 PFAM Glycosyl transferase family 2 - - - 3.405e-299 941.0
HFD2_k127_6650282_1 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 1.686e-265 848.0
HFD2_k127_6650282_10 Penicillin amidase K01434 - 3.5.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000008342 281.0
HFD2_k127_6650282_11 NADP oxidoreductase coenzyme F420-dependent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007401 246.0
HFD2_k127_6650282_12 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000004019 221.0
HFD2_k127_6650282_13 Protein of unknown function (DUF3570) - - - 0.0000000000000000000000000000000000000000000000000000362 204.0
HFD2_k127_6650282_14 Uncharacterized ACR, COG1993 K06199,K09137 - - 0.0000000000000000000000000000000000000000000000002277 186.0
HFD2_k127_6650282_15 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000006277 178.0
HFD2_k127_6650282_16 Transcriptional regulator sugar kinase K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000002017 182.0
HFD2_k127_6650282_17 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000009981 176.0
HFD2_k127_6650282_18 Redoxin - - - 0.00000000000000000000000000000000000000000002215 170.0
HFD2_k127_6650282_19 Mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000002598 160.0
HFD2_k127_6650282_2 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 2.17e-196 629.0
HFD2_k127_6650282_20 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000004484 131.0
HFD2_k127_6650282_21 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.0000000000000000000000000001013 121.0
HFD2_k127_6650282_22 Histidine kinase K07642 - 2.7.13.3 0.000000000000000000000000001102 131.0
HFD2_k127_6650282_23 Tetratricopeptide repeat - - - 0.000000000000000000000002888 119.0
HFD2_k127_6650282_24 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.000000000000000001105 99.0
HFD2_k127_6650282_25 - - - - 0.0000000000000000303 97.0
HFD2_k127_6650282_26 Domain of unknown function (DUF4266) - - - 0.00000000000003783 82.0
HFD2_k127_6650282_27 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000007621 71.0
HFD2_k127_6650282_28 - - - - 0.00000008622 60.0
HFD2_k127_6650282_29 Protein of unknown function (DUF2934) - - - 0.00002072 49.0
HFD2_k127_6650282_3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 569.0
HFD2_k127_6650282_4 acyl-CoA dehydrogenase activity K00252 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.3.8.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003377 518.0
HFD2_k127_6650282_5 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 482.0
HFD2_k127_6650282_6 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 478.0
HFD2_k127_6650282_7 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 463.0
HFD2_k127_6650282_8 pyrroloquinoline quinone binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005359 399.0
HFD2_k127_6650282_9 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004557 331.0
HFD2_k127_6679661_0 Outer membrane receptor - - - 0.0000003912 63.0
HFD2_k127_6702559_0 AMP-binding enzyme C-terminal domain K04110 - 6.2.1.25 1.544e-196 626.0
HFD2_k127_6702559_1 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 572.0
HFD2_k127_6702559_10 Belongs to the short-chain dehydrogenases reductases (SDR) family K00019,K07535 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.30 0.00000000000000000000000000000000000000000000000000004349 207.0
HFD2_k127_6702559_11 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000008406 141.0
HFD2_k127_6702559_12 - - - - 0.0001577 50.0
HFD2_k127_6702559_2 COG NOG10142 non supervised orthologous group - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007298 468.0
HFD2_k127_6702559_3 PFAM amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004133 460.0
HFD2_k127_6702559_4 NADH:flavin oxidoreductase / NADH oxidase family K09461 - 1.14.13.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 410.0
HFD2_k127_6702559_5 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 327.0
HFD2_k127_6702559_6 Belongs to the glycosyl hydrolase 18 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 306.0
HFD2_k127_6702559_7 enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001224 281.0
HFD2_k127_6702559_8 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001772 273.0
HFD2_k127_6702559_9 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000000000000000000000000000000000000003325 223.0
HFD2_k127_6803416_0 Putative tRNA binding domain K01874 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 417.0
HFD2_k127_6803416_1 TatD related DNase K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.0000000000000000000000000000000000000000000000000009225 193.0
HFD2_k127_6803416_2 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000007061 169.0
HFD2_k127_6803416_3 AntiSigma factor - - - 0.0000000000000000000000000000000894 137.0
HFD2_k127_6803416_4 S-layer homology domain - - - 0.0000000000000000000000001659 124.0
HFD2_k127_6803416_5 Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases. - - - 0.0000485 57.0
HFD2_k127_6999710_0 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 376.0
HFD2_k127_6999710_1 - - - - 0.0000501 55.0
HFD2_k127_6999710_2 cellulase activity K07019 - - 0.0001543 55.0
HFD2_k127_7003481_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 3.74e-257 822.0
HFD2_k127_7003481_1 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004333 467.0
HFD2_k127_7003481_10 Peptidase M56 - - - 0.0000000000000000000000000000000002243 148.0
HFD2_k127_7003481_11 Bacterial SH3 domain - - - 0.00000000000000000000001855 117.0
HFD2_k127_7003481_12 peptidase - - - 0.0000000000001867 85.0
HFD2_k127_7003481_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 451.0
HFD2_k127_7003481_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004045 463.0
HFD2_k127_7003481_4 phosphorelay signal transduction system K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 458.0
HFD2_k127_7003481_5 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006174 428.0
HFD2_k127_7003481_6 Deoxynucleoside kinase - - - 0.0000000000000000000000000000000000000000000000000000000002255 212.0
HFD2_k127_7003481_7 PFAM peptidase M6, immune inhibitor A - - - 0.0000000000000000000000000000000000000000000000000000000005654 230.0
HFD2_k127_7003481_8 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000001099 215.0
HFD2_k127_7003481_9 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000009999 199.0
HFD2_k127_7039681_0 succinate dehydrogenase K00239 GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363 1.3.5.1,1.3.5.4 6.968e-259 818.0
HFD2_k127_7039681_1 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 369.0
HFD2_k127_7039681_2 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K03520 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 334.0
HFD2_k127_7039681_3 membrane - - - 0.000000000000000000000000000000000000000000000000278 179.0
HFD2_k127_7045623_0 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000002276 205.0
HFD2_k127_7045623_1 bacterial-type flagellum-dependent cell motility - - - 0.00000000000000000000000000000000000000000001035 189.0
HFD2_k127_7045623_2 oligosaccharyl transferase activity - - - 0.000000000000008367 89.0
HFD2_k127_7066978_0 long-chain fatty acid transport protein - - - 0.0000000000000000000000000000000000000000000000000899 189.0
HFD2_k127_7066978_1 Peptidase M56 - - - 0.000000001512 70.0
HFD2_k127_7066978_2 Belongs to the peptidase S8 family - - - 0.0007058 43.0
HFD2_k127_70866_0 ferredoxin-NADP+ reductase activity - - - 0.00000000000000000000000000000000003786 148.0
HFD2_k127_70866_1 L-lysine 6-monooxygenase (NADPH-requiring) - - - 0.0000000000000000000000000001196 123.0
HFD2_k127_70866_2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines K01476,K01480 GO:0003674,GO:0003824,GO:0004053,GO:0006082,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 3.5.3.1,3.5.3.11 0.000000000000000000001573 103.0
HFD2_k127_7092289_0 L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 375.0
HFD2_k127_7092289_1 Belongs to the citrate synthase family K01647 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004785 383.0
HFD2_k127_7092289_2 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001586 294.0
HFD2_k127_7092289_3 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.00000000000000000000000000000000000000000003118 184.0
HFD2_k127_7092289_4 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000001467 170.0
HFD2_k127_7092289_5 cellulose binding - - - 0.0000000000002545 84.0
HFD2_k127_7105841_0 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009756 596.0
HFD2_k127_7105841_1 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 537.0
HFD2_k127_7105841_10 serine-type endopeptidase activity K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000000000000000000000000000001709 141.0
HFD2_k127_7105841_11 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000000001441 108.0
HFD2_k127_7105841_12 Belongs to the ComB family K05979 - 3.1.3.71 0.000000000000000007112 96.0
HFD2_k127_7105841_2 PFAM type II secretion system protein E K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009359 403.0
HFD2_k127_7105841_3 Enoyl-(Acyl carrier protein) reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000005542 265.0
HFD2_k127_7105841_4 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000001422 263.0
HFD2_k127_7105841_5 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000001677 190.0
HFD2_k127_7105841_6 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.0000000000000000000000000000000000000000000000002315 201.0
HFD2_k127_7105841_7 Acetyl-CoA carboxylase, biotin carboxyl carrier protein K01571,K01960 - 4.1.1.3,6.4.1.1 0.0000000000000000000000000000000000004542 151.0
HFD2_k127_7105841_8 repeat-containing protein - - - 0.000000000000000000000000000000000008571 159.0
HFD2_k127_7105841_9 ECF sigma factor K03088 - - 0.00000000000000000000000000000000003447 142.0
HFD2_k127_7107436_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03694,K03695 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0 1077.0
HFD2_k127_7107436_1 Oxidoreductase molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004886 255.0
HFD2_k127_7107436_2 Outer membrane protein beta-barrel family K16087,K16092 - - 0.00000000000000000000000000000000000000000000000933 197.0
HFD2_k127_7107436_3 diguanylate cyclase - - - 0.0000000000000000000000000000002112 140.0
HFD2_k127_7107436_4 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.000000000000000000000000000000744 127.0
HFD2_k127_7107436_5 PFAM Class I peptide chain release factor K15034 - - 0.0000000000000000005342 90.0
HFD2_k127_7111749_0 Alpha-L-arabinofuranosidase B, catalytic - - - 1.585e-252 791.0
HFD2_k127_7157154_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 520.0
HFD2_k127_7157154_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 512.0
HFD2_k127_7157154_2 PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 331.0
HFD2_k127_7157154_3 electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008528 306.0
HFD2_k127_7157154_4 electron transfer activity K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000000000002407 255.0
HFD2_k127_7157154_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000776 258.0
HFD2_k127_7157154_6 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000004871 199.0
HFD2_k127_7157154_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000005325 175.0
HFD2_k127_7157154_8 2 iron, 2 sulfur cluster binding K00334,K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000001482 173.0
HFD2_k127_7157154_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.6.5.3 0.00000000000000000000000000000000000001622 148.0
HFD2_k127_7161410_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1301.0
HFD2_k127_7161410_1 Pkd domain containing protein - - - 2.617e-268 852.0
HFD2_k127_7161410_10 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.00000000000000000000000000000000000000000000000000001274 200.0
HFD2_k127_7161410_11 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000001075 198.0
HFD2_k127_7161410_13 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000000000001601 159.0
HFD2_k127_7161410_14 type II secretion system protein K - - - 0.000000000000000000000000000001035 135.0
HFD2_k127_7161410_15 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000002963 123.0
HFD2_k127_7161410_16 AraC-like ligand binding domain - - - 0.0000000000000000000002195 113.0
HFD2_k127_7161410_17 Archease protein family (MTH1598/TM1083) - - - 0.000000000000001849 85.0
HFD2_k127_7161410_18 COG0474 Cation transport ATPase K01531 - 3.6.3.2 0.0000000002734 64.0
HFD2_k127_7161410_19 Galactose oxidase, central domain - - - 0.0000002108 64.0
HFD2_k127_7161410_2 Belongs to the RtcB family K14415 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004919 608.0
HFD2_k127_7161410_20 peptidase activity, acting on L-amino acid peptides K01337,K20276 - 3.4.21.50 0.0001534 55.0
HFD2_k127_7161410_3 Multicopper oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008897 530.0
HFD2_k127_7161410_4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005035 510.0
HFD2_k127_7161410_5 COG0577 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 329.0
HFD2_k127_7161410_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 316.0
HFD2_k127_7161410_7 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002028 303.0
HFD2_k127_7161410_8 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003851 269.0
HFD2_k127_7161410_9 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.00000000000000000000000000000000000000000000000000000002558 220.0
HFD2_k127_7162486_0 Aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000627 510.0
HFD2_k127_7162486_1 ATPase associated with various cellular K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006369 441.0
HFD2_k127_7162486_10 - - - - 0.000000000000000001199 96.0
HFD2_k127_7162486_11 subunit of a heme lyase K02198,K02200,K04016,K04017,K04018 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098567,GO:1901564 - 0.000000000000000009087 96.0
HFD2_k127_7162486_12 repeat protein - - - 0.000000000002132 79.0
HFD2_k127_7162486_13 Belongs to the peptidase S8 family - - - 0.00000009707 64.0
HFD2_k127_7162486_14 - - - - 0.0001105 55.0
HFD2_k127_7162486_2 Protein of unknown function DUF58 - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003205 320.0
HFD2_k127_7162486_3 von Willebrand factor (vWF) type A domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 314.0
HFD2_k127_7162486_4 enterobactin catabolic process K07214 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001285 267.0
HFD2_k127_7162486_5 von Willebrand factor (vWF) type A domain K07114,K12511 - - 0.000000000000000000000000000000000000000000000000000000000000000001228 246.0
HFD2_k127_7162486_6 Oxygen tolerance - - - 0.00000000000000000000000000000000000000000000000000000000000003934 245.0
HFD2_k127_7162486_7 - - - - 0.000000000000000000000000000000000000000000000001666 187.0
HFD2_k127_7162486_8 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000001165 172.0
HFD2_k127_7162486_9 Bacterial SH3 domain - - - 0.0000000000000000001465 99.0
HFD2_k127_7166613_0 Ribosomal protein S1 K02945,K03527,K12132 GO:0005575,GO:0005576,GO:0018995,GO:0020003,GO:0030430,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0065010 1.17.7.4,2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005027 429.0
HFD2_k127_7166613_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009492 348.0
HFD2_k127_7166613_2 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573,K12585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003183 329.0
HFD2_k127_7166613_3 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000001231 184.0
HFD2_k127_7166613_4 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000601 141.0
HFD2_k127_7297927_0 peptidyl-prolyl isomerase K03769 - 5.2.1.8 0.000000000001226 82.0
HFD2_k127_7297927_1 COG1073 Hydrolases of the alpha beta superfamily - - - 0.00005038 53.0
HFD2_k127_7314430_0 amino acid activation for nonribosomal peptide biosynthetic process K17713,K20952 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 391.0
HFD2_k127_7323579_0 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 1.644e-196 627.0
HFD2_k127_7323579_1 pyrroloquinoline quinone binding K01176 - 3.2.1.1 0.0000000000000000000000000000000000000001646 167.0
HFD2_k127_7370820_0 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 475.0
HFD2_k127_7370820_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 295.0
HFD2_k127_7370820_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000004771 256.0
HFD2_k127_7370820_3 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000001412 195.0
HFD2_k127_7370820_4 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.00000000000000000000000000000000000000002565 172.0
HFD2_k127_7370820_5 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 - - 0.000000000000000000000000000000000000002059 154.0
HFD2_k127_7370820_6 Bacterial Ig-like domain K07156 - - 0.00000000000000008607 93.0
HFD2_k127_7370820_7 PKD domain - - - 0.00000000000001967 88.0
HFD2_k127_7370820_8 Binds directly to 16S ribosomal RNA K02968 - - 0.00000005186 58.0
HFD2_k127_7408641_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006256 541.0
HFD2_k127_7408641_1 COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming) K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 511.0
HFD2_k127_7408641_10 RecB family - - - 0.000000000000000000000001117 117.0
HFD2_k127_7408641_11 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000003345 107.0
HFD2_k127_7408641_12 PKD domain - - - 0.000000000003067 80.0
HFD2_k127_7408641_13 Serine aminopeptidase, S33 K06889 - - 0.000000000008029 76.0
HFD2_k127_7408641_2 Belongs to the enoyl-CoA hydratase isomerase family K01782,K01825 - 1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 518.0
HFD2_k127_7408641_3 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 420.0
HFD2_k127_7408641_4 Trypsin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009456 382.0
HFD2_k127_7408641_5 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007523 363.0
HFD2_k127_7408641_6 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760,K15780 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.8,6.3.4.19 0.0000000000000000000000000000000000000000000000006148 182.0
HFD2_k127_7408641_7 lipase activity K15349 - - 0.0000000000000000000000000000000000000000001325 179.0
HFD2_k127_7408641_8 PFAM membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.0000000000000000000000000000000000000001197 166.0
HFD2_k127_7408641_9 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000001217 160.0
HFD2_k127_7425960_0 PFAM Glycoside hydrolase 15-related - - - 2.703e-197 623.0
HFD2_k127_7425960_1 peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 473.0
HFD2_k127_7452429_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001237 290.0
HFD2_k127_7452429_1 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001235 274.0
HFD2_k127_7452429_2 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000001124 217.0
HFD2_k127_7462895_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003576 598.0
HFD2_k127_7462895_1 Beta-eliminating lyase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003975 353.0
HFD2_k127_7462895_10 L-methionine salvage from methylthioadenosine K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000395 122.0
HFD2_k127_7462895_2 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 335.0
HFD2_k127_7462895_3 tail specific protease K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004781 312.0
HFD2_k127_7462895_4 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009358 310.0
HFD2_k127_7462895_5 Putative neutral zinc metallopeptidase K06973 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001154 262.0
HFD2_k127_7462895_6 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003647 260.0
HFD2_k127_7462895_7 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000001263 249.0
HFD2_k127_7462895_8 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000004604 211.0
HFD2_k127_7462895_9 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000003675 134.0
HFD2_k127_7469430_0 N-terminal domain of Peptidase_S41 in eukaryotic IRBP - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004982 291.0
HFD2_k127_7469430_1 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005213 278.0
HFD2_k127_7469430_2 membrane - - - 0.000000000000000000000000000000000000000000000000000001194 210.0
HFD2_k127_7522270_0 Multicopper oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008617 595.0
HFD2_k127_7522270_1 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K04127,K11325,K21174 - 5.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003694 478.0
HFD2_k127_7522270_10 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.0000000000000000000000000000000000000000000000004522 179.0
HFD2_k127_7522270_11 Bacterial extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000002597 187.0
HFD2_k127_7522270_12 Protein of unknown function (DUF1361) - - - 0.00000000000000000000000000000000000000000005566 168.0
HFD2_k127_7522270_13 sporulation protein K06381 - - 0.000000000000000000000000000000000000000004373 178.0
HFD2_k127_7522270_14 endonuclease activity K07451 - - 0.00000000000000000000000000000000000003622 160.0
HFD2_k127_7522270_15 TIGRFAM MazG family protein K02499,K04765 - 3.6.1.9 0.00000000000000000000000000000000000114 143.0
HFD2_k127_7522270_16 cellulose binding K00505 - 1.14.18.1 0.00000000000002322 87.0
HFD2_k127_7522270_17 Domain of unknown function (DUF1844) - - - 0.00000000000005432 78.0
HFD2_k127_7522270_19 Calcium-activated chloride channel regulator K05027,K05030 GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005215,GO:0005216,GO:0005229,GO:0005253,GO:0005254,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006821,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008509,GO:0015075,GO:0015103,GO:0015108,GO:0015267,GO:0015276,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0016324,GO:0016787,GO:0019538,GO:0022803,GO:0022834,GO:0022836,GO:0022838,GO:0022839,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0043170,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045177,GO:0051179,GO:0051234,GO:0055085,GO:0061778,GO:0070011,GO:0071704,GO:0071944,GO:0098590,GO:0098656,GO:0098660,GO:0098661,GO:0140096,GO:1901564,GO:1902476 - 0.000003032 61.0
HFD2_k127_7522270_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009411 454.0
HFD2_k127_7522270_3 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006083 381.0
HFD2_k127_7522270_4 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 374.0
HFD2_k127_7522270_5 DEAD-like helicases superfamily K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 329.0
HFD2_k127_7522270_6 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007387 312.0
HFD2_k127_7522270_7 Arginase family K01480 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000178 280.0
HFD2_k127_7522270_8 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000528 210.0
HFD2_k127_7522270_9 cellulase activity K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000001774 209.0
HFD2_k127_7556537_0 PFAM Peptidase M29, aminopeptidase II K19689 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000453 491.0
HFD2_k127_7556537_1 ABC transporter C-terminal domain K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 454.0
HFD2_k127_7556537_2 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000001239 182.0
HFD2_k127_7556537_4 beta-fructofuranosidase activity - - - 0.000000000000000000003583 109.0
HFD2_k127_7556537_5 - - - - 0.000001334 57.0
HFD2_k127_7556537_6 FlgD Ig-like domain - - - 0.0002408 54.0
HFD2_k127_7676282_0 Cytochrome C assembly protein - - - 1.398e-203 661.0
HFD2_k127_7676282_1 HI0933-like protein K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 304.0
HFD2_k127_7676282_2 OPT oligopeptide transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 308.0
HFD2_k127_7676282_3 FlgD Ig-like domain - - - 0.0000000000000000000000000003783 131.0
HFD2_k127_7676282_4 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000008176 116.0
HFD2_k127_7676282_5 - - - - 0.00000000000000001341 93.0
HFD2_k127_7676282_6 PFAM Integrase catalytic region - - - 0.000000005423 69.0
HFD2_k127_7905183_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.219e-319 1000.0
HFD2_k127_7905183_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 5.015e-246 777.0
HFD2_k127_7905183_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 401.0
HFD2_k127_7905183_3 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000008414 202.0
HFD2_k127_7905183_4 phosphoglycolate phosphatase activity - - - 0.00002176 55.0
HFD2_k127_7905183_5 Protein of unknown function (DUF721) - - - 0.00004497 54.0
HFD2_k127_7905183_6 phosphohistidine phosphatase, SixA K08296 - - 0.0005401 43.0
HFD2_k127_7913048_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 2.159e-236 769.0
HFD2_k127_7913048_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 494.0
HFD2_k127_7913048_10 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K02482 - 2.7.13.3 0.00000000000000000003374 106.0
HFD2_k127_7913048_11 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K12976,K22110 - - 0.00000000001531 76.0
HFD2_k127_7913048_12 Outer membrane protein beta-barrel domain - - - 0.00000004911 63.0
HFD2_k127_7913048_13 - - - - 0.0000001228 62.0
HFD2_k127_7913048_2 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840 - 5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 377.0
HFD2_k127_7913048_3 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009109 343.0
HFD2_k127_7913048_4 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003097 276.0
HFD2_k127_7913048_5 endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000002458 130.0
HFD2_k127_7913048_6 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000009247 131.0
HFD2_k127_7913048_7 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000005324 130.0
HFD2_k127_7913048_8 PFAM thioesterase superfamily K07107 - - 0.00000000000000000000000008972 119.0
HFD2_k127_7913048_9 Histidine kinase K01768,K12132 - 2.7.11.1,4.6.1.1 0.000000000000000000000007985 112.0
HFD2_k127_7925177_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0 1264.0
HFD2_k127_7925177_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 7.838e-205 672.0
HFD2_k127_7925177_10 Hexapeptide repeat of succinyl-transferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006841 298.0
HFD2_k127_7925177_11 with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine K01658,K01664 - 2.6.1.85,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000002396 267.0
HFD2_k127_7925177_12 Dienelactone hydrolase family K06999 - - 0.000000000000000000000000000000000000000000000000000000000000000000004013 240.0
HFD2_k127_7925177_13 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000009083 238.0
HFD2_k127_7925177_14 3-phytase (Myo-inositol-hexaphosphate 3-phosphohydrolase) K01083 - 3.1.3.8 0.000000000000000000000000000000000000000000000000000000000000005481 234.0
HFD2_k127_7925177_15 Belongs to the TrpC family K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000005598 199.0
HFD2_k127_7925177_16 PFAM ATP-binding region ATPase domain protein K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000001542 196.0
HFD2_k127_7925177_17 Phosphodiester glycosidase - - - 0.000000000000000000000000000000000000000000000005277 181.0
HFD2_k127_7925177_18 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000009639 180.0
HFD2_k127_7925177_19 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000143 147.0
HFD2_k127_7925177_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 528.0
HFD2_k127_7925177_20 Acid phosphatase vanadium-dependent haloperoxidase related K09775 - - 0.00000000000000000000000000000001015 131.0
HFD2_k127_7925177_21 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000002126 135.0
HFD2_k127_7925177_22 RDD family - - - 0.00000000000000000000000000008717 124.0
HFD2_k127_7925177_23 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000007084 129.0
HFD2_k127_7925177_24 Lipopolysaccharide-assembly - - - 0.0000000000007469 76.0
HFD2_k127_7925177_26 Evidence 5 No homology to any previously reported sequences - - - 0.0000002071 63.0
HFD2_k127_7925177_27 Psort location Cytoplasmic, score K02340 - 2.7.7.7 0.00007036 55.0
HFD2_k127_7925177_3 Anthranilate synthase component I, N terminal region K01657,K13503 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 509.0
HFD2_k127_7925177_4 Aldehyde dehydrogenase family K00135,K08324 GO:0001505,GO:0003674,GO:0003824,GO:0004777,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006520,GO:0006525,GO:0006527,GO:0006576,GO:0006595,GO:0006598,GO:0006807,GO:0008150,GO:0008152,GO:0009013,GO:0009056,GO:0009060,GO:0009063,GO:0009064,GO:0009065,GO:0009308,GO:0009310,GO:0009445,GO:0009447,GO:0009448,GO:0009450,GO:0009987,GO:0015980,GO:0016020,GO:0016054,GO:0016491,GO:0016620,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0034641,GO:0042133,GO:0042135,GO:0042402,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044464,GO:0045333,GO:0046395,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:0072329,GO:0072350,GO:0097164,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.2.1.16,1.2.1.20,1.2.1.24,1.2.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003401 482.0
HFD2_k127_7925177_5 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 432.0
HFD2_k127_7925177_6 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008663 415.0
HFD2_k127_7925177_7 Oxidoreductase family, NAD-binding Rossmann fold K13018 - 2.3.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007406 362.0
HFD2_k127_7925177_8 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007864 340.0
HFD2_k127_7925177_9 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 338.0
HFD2_k127_7926488_0 Beta-eliminating lyase K01667 - 4.1.99.1 2.317e-218 685.0
HFD2_k127_7926488_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000742 332.0
HFD2_k127_7926488_2 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000001579 254.0
HFD2_k127_7926488_3 Belongs to the UPF0173 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000002058 242.0
HFD2_k127_7926488_4 Peroxiredoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000007979 192.0
HFD2_k127_7926488_5 ATP-dependent protease La (LON) substrate-binding domain K01338,K07157 - 3.4.21.53 0.0000000000000000000001289 110.0
HFD2_k127_7926488_6 CAAX protease self-immunity K07052 - - 0.00000000000000003271 93.0
HFD2_k127_7926488_7 Helix-hairpin-helix motif - - - 0.0000007013 59.0
HFD2_k127_7926488_8 DSBA-like thioredoxin domain - - - 0.0001993 51.0
HFD2_k127_7981562_0 Peptidase dimerisation domain K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005906 391.0
HFD2_k127_7981562_1 Phytase K01083 - 3.1.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007301 366.0
HFD2_k127_7981562_10 cellulase activity K20276 - - 0.00000000008069 73.0
HFD2_k127_7981562_11 Tetratricopeptide repeat - - - 0.0000006331 63.0
HFD2_k127_7981562_2 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007042 297.0
HFD2_k127_7981562_3 ABC transporter K01990,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001654 275.0
HFD2_k127_7981562_4 - - - - 0.000000000000000000000000000000006353 147.0
HFD2_k127_7981562_5 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 2.1.1.63 0.00000000000000000000000000002216 126.0
HFD2_k127_7981562_6 YceI-like domain - - - 0.00000000000000000000003578 111.0
HFD2_k127_7981562_7 isoprenylcysteine carboxyl methyltransferase - - - 0.0000000000000000000003461 109.0
HFD2_k127_7981562_8 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000002016 89.0
HFD2_k127_7981562_9 Membrane - - - 0.00000000003299 71.0
HFD2_k127_7988029_0 PFAM Alcohol dehydrogenase, zinc-binding K00001 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 321.0
HFD2_k127_7988029_1 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004847 299.0
HFD2_k127_7988029_2 chromosome segregation K03497 - - 0.0000000000000000002382 104.0
HFD2_k127_7988029_3 Polymerase - - - 0.00002959 55.0
HFD2_k127_8050658_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 415.0
HFD2_k127_8050658_1 GHMP kinases C terminal K07031 - 2.7.1.168 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005401 362.0
HFD2_k127_8050658_10 Nucleotidyl transferase K15669 - 2.7.7.71 0.0000000000000000000000000000000000001183 161.0
HFD2_k127_8050658_11 Tetratricopeptide repeat - - - 0.0000000000000000000000000000001217 143.0
HFD2_k127_8050658_12 Glycosyltransferase Family 4 - - - 0.00000000000000000000002254 108.0
HFD2_k127_8050658_13 Polysaccharide biosynthesis protein - - - 0.000000000000000000001146 111.0
HFD2_k127_8050658_14 Two component regulator propeller - - - 0.000000001036 72.0
HFD2_k127_8050658_15 Methionine biosynthesis protein MetW - - - 0.00000003366 66.0
HFD2_k127_8050658_16 Acetyltransferase (GNAT) domain - - - 0.0000004143 61.0
HFD2_k127_8050658_17 Two component regulator propeller - - - 0.0000007885 63.0
HFD2_k127_8050658_2 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008114 343.0
HFD2_k127_8050658_3 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000035 323.0
HFD2_k127_8050658_4 Bacterial membrane protein, YfhO - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007294 311.0
HFD2_k127_8050658_5 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009268 282.0
HFD2_k127_8050658_6 Glycosyl transferase family 2 K07011 - - 0.0000000000000000000000000000000000000000000000007453 193.0
HFD2_k127_8050658_7 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000001038 187.0
HFD2_k127_8050658_8 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000001348 190.0
HFD2_k127_8050658_9 Group 1 family - - - 0.0000000000000000000000000000000000000000349 167.0
HFD2_k127_8056696_0 COG3119 Arylsulfatase A and related enzymes K01130 - 3.1.6.1 3.151e-246 778.0
HFD2_k127_8056696_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 8.988e-227 723.0
HFD2_k127_8056696_10 alginic acid biosynthetic process K07218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003687 296.0
HFD2_k127_8056696_11 Endonuclease Exonuclease Phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001348 259.0
HFD2_k127_8056696_12 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000001551 271.0
HFD2_k127_8056696_13 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001073 271.0
HFD2_k127_8056696_14 Endonuclease Exonuclease Phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000002052 241.0
HFD2_k127_8056696_15 YD repeat - - - 0.0000000000000000000000000000000000000000000000000000000007108 233.0
HFD2_k127_8056696_16 COG0840 Methyl-accepting chemotaxis protein - - - 0.0000000000000000000000000000000000000000000000000002785 207.0
HFD2_k127_8056696_17 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000001285 161.0
HFD2_k127_8056696_18 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000001573 144.0
HFD2_k127_8056696_19 Copper homeostasis K06079 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0010810,GO:0016020,GO:0019867,GO:0030155,GO:0030312,GO:0030313,GO:0031975,GO:0042802,GO:0044462,GO:0044464,GO:0050789,GO:0065007,GO:0071944 - 0.00000000000000000000000000000000004455 147.0
HFD2_k127_8056696_2 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases K00174 - 1.2.7.11,1.2.7.3 2.429e-222 713.0
HFD2_k127_8056696_20 Pfam Activator of Hsp90 ATPase - - - 0.00000000000000000000002016 112.0
HFD2_k127_8056696_21 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella K01195 - 3.2.1.31 0.00000000000000006796 96.0
HFD2_k127_8056696_22 cellulose binding K01179,K21449 - 3.2.1.4 0.000000018 66.0
HFD2_k127_8056696_23 cellulose binding K01179,K21449 - 3.2.1.4 0.0000006071 61.0
HFD2_k127_8056696_24 Putative porin - - - 0.0003154 53.0
HFD2_k127_8056696_3 Peptidase family M28 K06016 - 3.5.1.6,3.5.1.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 601.0
HFD2_k127_8056696_4 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005486 485.0
HFD2_k127_8056696_5 2 iron, 2 sulfur cluster binding K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003719 428.0
HFD2_k127_8056696_6 Peptidase S9 prolyl oligopeptidase active site - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 425.0
HFD2_k127_8056696_7 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005343 351.0
HFD2_k127_8056696_8 PFAM Acetamidase Formamidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 357.0
HFD2_k127_8056696_9 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006979 323.0
HFD2_k127_8060968_0 SMART Elongator protein 3 MiaB NifB - - - 8.798e-237 741.0
HFD2_k127_8060968_1 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004025 323.0
HFD2_k127_8060968_2 AP endonuclease family 2 K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000006329 239.0
HFD2_k127_8060968_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000002112 187.0
HFD2_k127_8060968_4 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000006727 179.0
HFD2_k127_8060968_5 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000101 182.0
HFD2_k127_8060968_6 May be involved in the biosynthesis of molybdopterin K03638,K03831 - 2.7.7.75 0.000000000000000000000000000003524 136.0
HFD2_k127_8060968_7 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.00002595 57.0
HFD2_k127_8089851_0 SMP-30/Gluconolaconase/LRE-like region K01053,K14274 - 3.1.1.17 6.108e-210 658.0
HFD2_k127_8089851_1 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 333.0
HFD2_k127_8089851_2 AraC-like ligand binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006993 257.0
HFD2_k127_8089851_3 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000000000008787 203.0
HFD2_k127_8089851_4 Protein of unknown function (DUF1706) - - - 0.0000000001816 68.0
HFD2_k127_8096115_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008497 439.0
HFD2_k127_8114702_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000759 397.0
HFD2_k127_8114702_1 lipoprotein transporter activity K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003495 349.0
HFD2_k127_8114702_2 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000005029 172.0
HFD2_k127_8144717_0 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 360.0
HFD2_k127_8144717_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 340.0
HFD2_k127_8144717_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003255 257.0
HFD2_k127_8144717_3 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000374 201.0
HFD2_k127_8144717_4 NnrS protein K07234 - - 0.000001427 60.0
HFD2_k127_8213609_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1102.0
HFD2_k127_8213609_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 5.058e-223 726.0
HFD2_k127_8213609_2 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.00000000000000000000000000003271 127.0
HFD2_k127_8213609_3 dolichyl monophosphate biosynthetic process K08591 - 2.3.1.15 0.000000000000000000007303 98.0
HFD2_k127_8213609_4 Cold shock protein K03704 - - 0.0000000000000002285 90.0
HFD2_k127_8239529_0 heat shock protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 446.0
HFD2_k127_8239529_1 heat shock protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001736 269.0
HFD2_k127_8239529_2 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000003815 221.0
HFD2_k127_8239529_3 ferredoxin-NADP+ reductase activity - - - 0.000000000000000000000000000000001425 142.0
HFD2_k127_82713_0 Berberine and berberine like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 602.0
HFD2_k127_82713_1 Penicillin amidase K01434 - 3.5.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 397.0
HFD2_k127_82713_10 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.0000000000001243 77.0
HFD2_k127_82713_11 Protein conserved in bacteria K20274 - - 0.000000000007744 79.0
HFD2_k127_82713_12 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.000000003221 64.0
HFD2_k127_82713_13 energy transducer activity K00700,K03832 - 2.4.1.18 0.0000002492 63.0
HFD2_k127_82713_14 chlorophyll binding - - - 0.0000009218 61.0
HFD2_k127_82713_15 response to pH - - - 0.000003033 59.0
HFD2_k127_82713_16 Tetratricopeptide repeat - - - 0.0000112 60.0
HFD2_k127_82713_17 ompA family - - - 0.0005173 52.0
HFD2_k127_82713_2 Cupin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002843 376.0
HFD2_k127_82713_3 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 344.0
HFD2_k127_82713_4 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 334.0
HFD2_k127_82713_5 alginic acid biosynthetic process K07218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001951 282.0
HFD2_k127_82713_6 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000003835 237.0
HFD2_k127_82713_7 - - - - 0.0000000000000000000000000000000000000001316 158.0
HFD2_k127_82713_8 MotA TolQ ExbB proton channel family K03561 - - 0.000000000000000000003214 102.0
HFD2_k127_82713_9 Tetratricopeptide repeat - - - 0.00000000000000000004073 104.0
HFD2_k127_8278351_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0050896,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008035 515.0
HFD2_k127_8278351_1 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005598 518.0
HFD2_k127_8278351_10 PFAM glycosyl transferase family 39 - - - 0.0000000000000000000000000000001688 139.0
HFD2_k127_8278351_11 OsmC-like protein K07397 - - 0.000000000000001863 90.0
HFD2_k127_8278351_2 PFAM ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005722 424.0
HFD2_k127_8278351_3 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 361.0
HFD2_k127_8278351_4 drug transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 335.0
HFD2_k127_8278351_5 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000008432 260.0
HFD2_k127_8278351_6 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000006095 222.0
HFD2_k127_8278351_7 Catalyzes the formation of 2-oxobutanoate from L-threonine or the formation of pyruvate from serine K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000009519 231.0
HFD2_k127_8278351_8 PFAM Major Facilitator Superfamily K08223 - - 0.000000000000000000000000000000000000000000000008166 188.0
HFD2_k127_8278351_9 Domain of unknown function (DUF4198) - - - 0.00000000000000000000000000000000000000000001461 170.0
HFD2_k127_8288298_0 AAA domain - - - 0.0 1125.0
HFD2_k127_8288298_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003857 605.0
HFD2_k127_8288298_2 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004501 457.0
HFD2_k127_8288298_3 Phage plasmid primase P4 family K06919 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008537 304.0
HFD2_k127_8288298_4 PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP K20276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000157 297.0
HFD2_k127_8288298_5 phosphoribosyltransferase K07100 - - 0.00000000000000000000000000000000000000000000000000000000001172 212.0
HFD2_k127_8288298_6 metallopeptidase activity K20276 - - 0.0000000000000000000000000000000000000000000001679 193.0
HFD2_k127_8288298_7 Glycosyl hydrolase family 70 K01142,K01176 - 3.1.11.2,3.2.1.1 0.000000001725 72.0
HFD2_k127_8288298_8 'Cold-shock' DNA-binding domain - - - 0.0000005483 56.0
HFD2_k127_8323735_0 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 578.0
HFD2_k127_8323735_1 PKD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005554 338.0
HFD2_k127_8323735_2 PKD domain containing protein - - - 0.0000000001242 76.0
HFD2_k127_8325455_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003586 366.0
HFD2_k127_8325455_1 PFAM NAD-dependent glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008072 289.0
HFD2_k127_8325455_2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000004243 255.0
HFD2_k127_8325455_3 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000104 145.0
HFD2_k127_8325455_4 Glycosyl transferase, family 2 K00786 - - 0.000000000000000000000000000000000331 141.0
HFD2_k127_8325455_5 regulatory protein, MerR - - - 0.0000000000000000000001531 102.0
HFD2_k127_8325455_6 protein secretion K09800 - - 0.000000001118 66.0
HFD2_k127_8325455_7 - - - - 0.0000314 48.0
HFD2_k127_8415070_0 TIGRFAM formate dehydrogenase, alpha subunit, archaeal-type K00123 - 1.17.1.9 2.828e-313 985.0
HFD2_k127_8415070_1 imidazolonepropionase activity K01443 - 3.5.1.25 4.417e-227 741.0
HFD2_k127_8415070_10 Belongs to the peptidase S41A family K06399 - 3.4.21.116 0.0000000000000000000000000000000000000000000000000008014 201.0
HFD2_k127_8415070_11 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000003768 182.0
HFD2_k127_8415070_12 Membrane - - - 0.000001276 57.0
HFD2_k127_8415070_13 O-acyltransferase activity K00661,K04042 - 2.3.1.157,2.3.1.79,2.7.7.23 0.00001974 56.0
HFD2_k127_8415070_2 Peptidase S9, prolyl oligopeptidase active site domain protein K01322 - 3.4.21.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005152 531.0
HFD2_k127_8415070_3 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit K11381 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004056 494.0
HFD2_k127_8415070_4 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008288 433.0
HFD2_k127_8415070_5 Bacterial protein of unknown function (DUF839) K07093 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003387 426.0
HFD2_k127_8415070_6 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 370.0
HFD2_k127_8415070_7 imidazolonepropionase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 372.0
HFD2_k127_8415070_8 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000005435 233.0
HFD2_k127_8415070_9 CDGSH-type zinc finger. Function unknown. - - - 0.000000000000000000000000000000000000000000000000000005134 217.0
HFD2_k127_8485201_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.0 1189.0
HFD2_k127_8485201_1 Beta-eliminating lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 481.0
HFD2_k127_8485201_2 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002995 451.0
HFD2_k127_8485201_3 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000001288 234.0
HFD2_k127_8485201_4 tRNA-splicing ligase RtcB - - - 0.0000000000000000000000000000000000000000001138 184.0
HFD2_k127_8485201_5 PFAM Polysaccharide biosynthesis protein - - - 0.000000000000005246 90.0
HFD2_k127_8485201_6 PFAM CobQ CobB MinD ParA nucleotide binding domain - - - 0.00000000000123 81.0
HFD2_k127_8485201_7 biosynthesis protein - - - 0.000001805 61.0
HFD2_k127_8485201_8 O-Antigen Polymerase - - - 0.000001884 62.0
HFD2_k127_8485201_9 NUBPL iron-transfer P-loop NTPase - - - 0.000008732 59.0
HFD2_k127_8523866_0 DNA polymerase K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0 1060.0
HFD2_k127_8523866_1 malonyl-CoA biosynthetic process K01962,K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008785 391.0
HFD2_k127_8523866_10 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000006091 97.0
HFD2_k127_8523866_11 Trm112p-like protein K09791 - - 0.00000000000002526 75.0
HFD2_k127_8523866_12 NHL repeat - - - 0.0000000004474 73.0
HFD2_k127_8523866_13 polysaccharide catabolic process K01179,K01218 - 3.2.1.4,3.2.1.78 0.000000008302 70.0
HFD2_k127_8523866_14 - - - - 0.000002976 59.0
HFD2_k127_8523866_15 - - - - 0.00001874 57.0
HFD2_k127_8523866_17 Recombinase zinc beta ribbon domain - - - 0.0006148 46.0
HFD2_k127_8523866_2 Propeptide_C25 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001352 310.0
HFD2_k127_8523866_3 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.0000000000000000000000000000000000000000000000000000000004966 232.0
HFD2_k127_8523866_4 Type II secretory pathway component ExeA K02450 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000008128 217.0
HFD2_k127_8523866_5 Evidence 5 No homology to any previously reported sequences K17713 - - 0.00000000000000000000000000000000000000000000000000001211 217.0
HFD2_k127_8523866_6 Glycoside hydrolase family 24 - - - 0.00000000000000000000000000000000000000000000000112 201.0
HFD2_k127_8523866_7 long-chain fatty acid transport protein - - - 0.00000000000000000000000000000000000000002725 165.0
HFD2_k127_8523866_8 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000002862 148.0
HFD2_k127_8523866_9 Peptidase family M23 - - - 0.00000000000000000000000003896 126.0
HFD2_k127_8540756_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 484.0
HFD2_k127_8540756_1 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008494 481.0
HFD2_k127_8540756_2 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000000000000000000000000000000000000001518 210.0
HFD2_k127_8540756_3 OsmC-like protein K09136 - - 0.0000000000000000000000000000000000000003511 154.0
HFD2_k127_8540756_4 DsrC like protein K11179 - - 0.00000000000000000000000000000003508 133.0
HFD2_k127_8540756_5 CHAT domain - - - 0.0000000000000000000000008412 117.0
HFD2_k127_8540756_6 Parallel beta-helix repeats - - - 0.0000000000005887 83.0
HFD2_k127_8540756_7 Protein conserved in bacteria - - - 0.0000000009982 73.0
HFD2_k127_8567194_0 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000004072 185.0
HFD2_k127_8567194_1 RNase_H superfamily K07502 - - 0.000000000000000000000000000000003772 147.0
HFD2_k127_8567194_2 PFAM Helicase conserved C-terminal domain K06877 - - 0.00000000000000000136 90.0
HFD2_k127_8567194_3 Probable zinc-ribbon domain - - - 0.00000000000001957 73.0
HFD2_k127_8626870_0 Sugar (and other) transporter K03446 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 535.0
HFD2_k127_8626870_1 E1-E2 ATPase K01534 - 3.6.3.3,3.6.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008158 535.0
HFD2_k127_8626870_2 Biotin-lipoyl like K03543 - - 0.00000000000000000000000000000000000000000000000302 177.0
HFD2_k127_8626870_3 P-type ATPase' K17686,K19597 - 3.6.3.54 0.0006607 53.0
HFD2_k127_8648358_0 RecQ zinc-binding K03654 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 625.0
HFD2_k127_8648358_1 ABC transporter transmembrane K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 583.0
HFD2_k127_8648358_2 Mitochondrial biogenesis AIM24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 402.0
HFD2_k127_8648358_3 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 2.5.1.120,2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 356.0
HFD2_k127_8648358_4 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004885 329.0
HFD2_k127_8648358_5 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000001331 168.0
HFD2_k127_8648358_6 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.0000000000000000000000000000266 132.0
HFD2_k127_8648358_7 Type II transport protein GspH K08084 - - 0.000000003084 68.0
HFD2_k127_8648358_8 Cna B domain protein - - - 0.0001541 55.0
HFD2_k127_8679112_0 Adenylosuccinate lyase C-terminus K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 501.0
HFD2_k127_8679112_1 PFAM SAICAR synthetase K01756,K01923 - 4.3.2.2,6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 307.0
HFD2_k127_8679112_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000009045 95.0
HFD2_k127_8679112_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0003674,GO:0003824,GO:0004642,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.0002845 44.0
HFD2_k127_8682578_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000539 546.0
HFD2_k127_8682578_1 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 433.0
HFD2_k127_8682578_10 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.000000000000000000000000000000003862 148.0
HFD2_k127_8682578_11 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000002472 105.0
HFD2_k127_8682578_12 amino acid activation for nonribosomal peptide biosynthetic process K17713,K20952 - - 0.00000000000000000385 99.0
HFD2_k127_8682578_13 - - - - 0.0000000008497 64.0
HFD2_k127_8682578_14 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K01179,K03832 - 3.2.1.4 0.000000002977 68.0
HFD2_k127_8682578_15 protein secretion - - - 0.000000007173 69.0
HFD2_k127_8682578_2 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 352.0
HFD2_k127_8682578_3 PFAM metal-dependent phosphohydrolase, HD sub domain - GO:0003674,GO:0003824,GO:0004112,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008081,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009187,GO:0009214,GO:0009987,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 355.0
HFD2_k127_8682578_4 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 298.0
HFD2_k127_8682578_5 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000007015 184.0
HFD2_k127_8682578_6 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000002439 163.0
HFD2_k127_8682578_7 Aerotolerance regulator N-terminal - - - 0.0000000000000000000000000000000000005237 160.0
HFD2_k127_8682578_8 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000002637 152.0
HFD2_k127_8682578_9 Methyltransferase small domain - - - 0.000000000000000000000000000000001382 140.0
HFD2_k127_933765_0 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 295.0
HFD2_k127_933765_1 endonuclease activity K07451 - - 0.00000000003037 68.0
HFD2_k127_964985_0 magnesium chelatase K03405 - 6.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004842 584.0
HFD2_k127_964985_1 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006116 507.0
HFD2_k127_964985_10 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000002587 184.0
HFD2_k127_964985_11 Belongs to the peptidase S8 family K08651,K14743 - 3.4.21.66 0.00000000000000000000000000000000000000000000007213 190.0
HFD2_k127_964985_12 Methyltransferase domain - - - 0.00000000000000000000000000000000000000003288 169.0
HFD2_k127_964985_13 CHAT domain - - - 0.00000000000000000000000000000000000002724 167.0
HFD2_k127_964985_14 FAD binding domain K11472 - - 0.0000000000000000000000000000000000003794 158.0
HFD2_k127_964985_15 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog - - - 0.00000000000000000000000000002967 125.0
HFD2_k127_964985_16 Endonuclease Exonuclease Phosphatase - - - 0.000000000000000000000004914 115.0
HFD2_k127_964985_17 - - - - 0.0002697 54.0
HFD2_k127_964985_2 PFAM FAD linked oxidase domain protein K00102,K00104 - 1.1.2.4,1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 457.0
HFD2_k127_964985_3 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000436 387.0
HFD2_k127_964985_4 Sortilin, neurotensin receptor 3, - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003806 346.0
HFD2_k127_964985_5 pilus organization K02674,K07004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 340.0
HFD2_k127_964985_6 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005921 310.0
HFD2_k127_964985_7 Family of unknown function (DUF1028) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 323.0
HFD2_k127_964985_8 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009949 268.0
HFD2_k127_964985_9 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000000000000000000000001564 220.0