logo

Overview

ID MAG01666
Name HFD2_bin.60
Sample SMP0044
Taxonomy
Kingdom Bacteria
Phylum Desulfobacterota_B
Class Binatia
Order UBA9968
Family UBA9968
Genus JACPFE01
Species
Assembly information
Completeness (%) 81.44
Contamination (%) 4.67
GC content (%) 58.0
N50 (bp) 5,906
Genome size (bp) 3,966,048

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3751

Gene name Description KEGG GOs EC E-value Score Sequence
HFD2_k127_1007824_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 3.818e-271 852.0
HFD2_k127_1007824_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000609 561.0
HFD2_k127_1007824_2 PFAM peptidase M16 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009605 402.0
HFD2_k127_1007824_3 dUTPase K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.00000000000000000000000000000000000000000000001292 177.0
HFD2_k127_1007824_4 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000401 124.0
HFD2_k127_1007824_5 aspartic-type endopeptidase activity K06985 - - 0.00000000000000000000002892 108.0
HFD2_k127_1007824_6 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity K00134,K00150,K03340 - 1.2.1.12,1.2.1.59,1.4.1.16 0.000000000000000001224 86.0
HFD2_k127_1010005_0 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000002286 253.0
HFD2_k127_1010005_1 - - - - 0.00000000000000000001939 96.0
HFD2_k127_1010125_0 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000000001223 222.0
HFD2_k127_1010125_1 NMT1-like family - - - 0.00000000000000000000000000000005938 137.0
HFD2_k127_1010125_2 NMT1/THI5 like K02051 - - 0.000000007441 63.0
HFD2_k127_1015953_0 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000002133 182.0
HFD2_k127_1015953_1 Amidohydrolase K07045 - - 0.0000000000002163 82.0
HFD2_k127_1022155_0 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005276 580.0
HFD2_k127_1022155_1 NMT1-like family K02051 - - 0.000000000000008946 87.0
HFD2_k127_1027342_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 3.343e-209 660.0
HFD2_k127_1027342_1 COG3221 ABC-type phosphate phosphonate transport system, periplasmic component K02044 - - 0.00000000000000000000000000000000000000000000001375 183.0
HFD2_k127_1027342_2 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000005984 53.0
HFD2_k127_1030399_0 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007088 332.0
HFD2_k127_1030399_1 PFAM amidohydrolase 2 - - - 0.000000000000000000000000000002643 121.0
HFD2_k127_1030399_2 dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000001004 86.0
HFD2_k127_1046684_0 Molydopterin dinucleotide binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007435 546.0
HFD2_k127_1046684_1 FAD binding domain K07077 - - 0.00000000000000004143 90.0
HFD2_k127_1047094_0 Binding-protein-dependent transport system inner membrane component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004834 339.0
HFD2_k127_1047094_1 PFAM ABC transporter K02010,K02017,K02062,K10112,K10199,K17314 - 3.6.3.29,3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 309.0
HFD2_k127_1047094_2 Glutathione S-transferase, C-terminal domain K07393 - 1.8.5.7 0.0000000000000000000000000000005328 123.0
HFD2_k127_1047094_3 Abc transporter K02012 - - 0.0000000000000000000005658 108.0
HFD2_k127_1047832_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 1.551e-194 629.0
HFD2_k127_1047832_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008848 277.0
HFD2_k127_1047832_2 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000001832 106.0
HFD2_k127_1051579_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001269 274.0
HFD2_k127_1051579_1 histidine kinase HAMP region domain protein K07716 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000008861 205.0
HFD2_k127_1052507_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 2.533e-199 646.0
HFD2_k127_1052507_1 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 562.0
HFD2_k127_1052507_2 transmembrane transport K02035,K15580 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006810,GO:0006811,GO:0006820,GO:0006857,GO:0006869,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010876,GO:0015711,GO:0015718,GO:0015721,GO:0015833,GO:0015849,GO:0015850,GO:0030288,GO:0030313,GO:0031975,GO:0033036,GO:0033218,GO:0042277,GO:0042597,GO:0042886,GO:0042939,GO:0044464,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0061077,GO:0071702,GO:0071705,GO:1900750 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007886 557.0
HFD2_k127_1052507_3 Conserved carboxylase domain K01571 - 4.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004113 411.0
HFD2_k127_1052507_4 PFAM Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000003782 224.0
HFD2_k127_1052507_5 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000002174 117.0
HFD2_k127_1052507_6 TIGRFAM RHS repeat-associated core domain - - - 0.000000008114 61.0
HFD2_k127_1053197_0 iron ion homeostasis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005202 270.0
HFD2_k127_1053197_1 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000000000000000000000000000000000001558 193.0
HFD2_k127_1053197_2 Asp/Glu/Hydantoin racemase K01799 - 5.2.1.1 0.0000000000000000000000000000002075 135.0
HFD2_k127_1053263_0 Molydopterin dinucleotide binding domain K10700,K17050 - 1.17.99.2 7.566e-267 850.0
HFD2_k127_1053263_1 Molydopterin dinucleotide binding domain K10700,K17050 - 1.17.99.2 4.142e-258 825.0
HFD2_k127_1053263_2 Molydopterin dinucleotide binding domain K10700,K17050 - 1.17.99.2 1.259e-225 725.0
HFD2_k127_1059384_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K18983 - 5.5.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000008431 268.0
HFD2_k127_1059384_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000005421 229.0
HFD2_k127_1059384_2 Luciferase-like monooxygenase - - - 0.000000000000000000008752 96.0
HFD2_k127_1064349_0 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 1.189e-199 626.0
HFD2_k127_1064349_1 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000437 350.0
HFD2_k127_1064349_10 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.00000004076 57.0
HFD2_k127_1064349_11 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000003686 51.0
HFD2_k127_1064349_12 oxidoreductase activity, acting on CH-OH group of donors K09386 - - 0.00001885 53.0
HFD2_k127_1064349_2 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000001516 237.0
HFD2_k127_1064349_3 [2Fe-2S] binding domain - - - 0.000000000000000000000000000000000000000000000000000003819 195.0
HFD2_k127_1064349_4 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000001663 203.0
HFD2_k127_1064349_5 NIPSNAP - - - 0.000000000000000000000000000000000000000000000001176 183.0
HFD2_k127_1064349_6 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000077 130.0
HFD2_k127_1064349_7 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.00000000000000000000000000255 120.0
HFD2_k127_1064349_8 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.00000000000000000000000005722 121.0
HFD2_k127_1064349_9 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000002202 76.0
HFD2_k127_1069304_0 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007604 533.0
HFD2_k127_1069304_1 Tripartite tricarboxylate transporter TctA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005123 457.0
HFD2_k127_1069304_11 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.00001458 51.0
HFD2_k127_1069304_12 Cupin domain K00450 - 1.13.11.4 0.00002978 52.0
HFD2_k127_1069304_2 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 394.0
HFD2_k127_1069304_3 Amidohydrolase K22213 - 4.1.1.52 0.000000000000000000000000000000000000000000000000000000000000000000006028 248.0
HFD2_k127_1069304_4 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) K05921 - 4.1.1.68 0.000000000000000000000000000000000000000000000000000000000000003854 229.0
HFD2_k127_1069304_5 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.000000000000000000008956 104.0
HFD2_k127_1069304_6 Substrate binding domain of ABC-type glycine betaine transport system K02051 - - 0.000000000000007756 86.0
HFD2_k127_1069304_7 NMT1-like family K02051 - - 0.0000000000001628 81.0
HFD2_k127_1069304_8 thiamine-containing compound biosynthetic process K02051 - - 0.000000000031 74.0
HFD2_k127_1069304_9 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.000000008589 67.0
HFD2_k127_1070212_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 608.0
HFD2_k127_1070212_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 530.0
HFD2_k127_1070212_10 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002382 251.0
HFD2_k127_1070212_11 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000001757 229.0
HFD2_k127_1070212_12 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000004334 171.0
HFD2_k127_1070212_13 Outer membrane protein (OmpH-like) K06142 - - 0.0000000000000003263 85.0
HFD2_k127_1070212_2 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 404.0
HFD2_k127_1070212_3 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007288 383.0
HFD2_k127_1070212_4 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009412 345.0
HFD2_k127_1070212_5 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 320.0
HFD2_k127_1070212_6 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008859 320.0
HFD2_k127_1070212_7 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 288.0
HFD2_k127_1070212_8 Protein of unknown function (DUF1009) K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009015 283.0
HFD2_k127_1070212_9 5,10-methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000002507 265.0
HFD2_k127_1075387_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 599.0
HFD2_k127_1075387_1 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM-like protein K03519 - 1.2.5.3 0.0000000000000000000000000000000000000005218 155.0
HFD2_k127_1075387_2 Psort location Cytoplasmic, score K03518 - 1.2.5.3 0.0000000000000000003933 103.0
HFD2_k127_1079708_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 GO:0000166,GO:0003674,GO:0003824,GO:0004362,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015036,GO:0015037,GO:0015038,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071949,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 404.0
HFD2_k127_1079708_1 ParB-like nuclease domain K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005107 333.0
HFD2_k127_1079708_2 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004978 267.0
HFD2_k127_1079708_3 Catalyzes the conversion of maleate to fumarate K01799 - 5.2.1.1 0.000001178 56.0
HFD2_k127_109011_0 PFAM isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 392.0
HFD2_k127_109011_1 LysR substrate binding domain K16135 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 387.0
HFD2_k127_109011_2 PFAM Tripartite tricarboxylate transporter TctA family K07793 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003651 245.0
HFD2_k127_109011_3 Tripartite tricarboxylate transporter TctB family K07794 - - 0.0000003293 58.0
HFD2_k127_1091167_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000003665 220.0
HFD2_k127_1091167_1 PFAM electron transport protein SCO1 SenC K07152 - - 0.0000000000000000000000000000000007607 139.0
HFD2_k127_1091167_2 response to copper ion K07156,K14166 - - 0.0000000000000000000000000000004466 126.0
HFD2_k127_1091167_3 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00000000000000000000000000001213 126.0
HFD2_k127_1091167_4 Copper resistance protein CopC K14166 - - 0.000000001036 63.0
HFD2_k127_1091167_6 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000001008 62.0
HFD2_k127_1091167_7 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000165 59.0
HFD2_k127_1091167_8 - - - - 0.0004528 48.0
HFD2_k127_1092707_0 FeS assembly protein SufD K07033,K09015 GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0050896,GO:0051186,GO:0071840 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007304 413.0
HFD2_k127_1092707_1 ABC transporter K09013 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 403.0
HFD2_k127_1092707_2 transcriptional regulator, Rrf2 family - - - 0.000000000000000005115 89.0
HFD2_k127_1110859_0 PFAM Transposase, IS111A IS1328 IS1533 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003673 257.0
HFD2_k127_1116159_0 NMT1/THI5 like K02051 - - 0.00000000000000000000000008972 119.0
HFD2_k127_1116159_1 - - - - 0.00000000000004554 74.0
HFD2_k127_1116159_2 NMT1-like family K02051 - - 0.000000000002872 78.0
HFD2_k127_1116159_3 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.00000003473 65.0
HFD2_k127_1117987_0 NAD(P)-binding Rossmann-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 605.0
HFD2_k127_1117987_1 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway K03707 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 3.5.99.2 0.0000000001514 63.0
HFD2_k127_1127130_0 Amidohydrolase K03392 - 4.1.1.45 0.00000000000000000000000000000000000000000000000006116 190.0
HFD2_k127_1127130_1 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000003224 150.0
HFD2_k127_1127130_2 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000004796 83.0
HFD2_k127_1134784_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000316 511.0
HFD2_k127_1134784_1 - - - - 0.000000000000000000000000000000000000000000000000000000000005458 216.0
HFD2_k127_1134784_2 Protein of unknown function (DUF1275) - - - 0.000000000000000000000000000000003518 141.0
HFD2_k127_1134784_3 ABC transporter, phosphonate, periplasmic substrate-binding protein K02051,K15553 - - 0.000000000000000000004145 104.0
HFD2_k127_1134975_0 transcription factor binding K02584,K12146,K12266,K15836,K21009 GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001150,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0042802,GO:0043170,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001141 - 8.224e-199 632.0
HFD2_k127_1134975_1 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 576.0
HFD2_k127_1134975_2 NADPH-dependent FMN reductase K19784 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000116 258.0
HFD2_k127_1134975_3 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000602 234.0
HFD2_k127_1134975_4 - - - - 0.00000000000000000000000000000000000000000000000000001252 196.0
HFD2_k127_1134975_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000002432 184.0
HFD2_k127_1134975_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000001348 94.0
HFD2_k127_1136454_0 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 491.0
HFD2_k127_1136454_1 branched-chain amino acid transport system, permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 404.0
HFD2_k127_1136454_10 Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002476 276.0
HFD2_k127_1136454_11 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000001509 202.0
HFD2_k127_1136454_12 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000001444 126.0
HFD2_k127_1136454_13 Protein involved in outer membrane biogenesis K07289 - - 0.0000000000000000000003219 111.0
HFD2_k127_1136454_2 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 386.0
HFD2_k127_1136454_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 378.0
HFD2_k127_1136454_4 Virulence factor BrkB K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009158 356.0
HFD2_k127_1136454_5 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006444 344.0
HFD2_k127_1136454_6 abc transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 312.0
HFD2_k127_1136454_7 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 299.0
HFD2_k127_1136454_8 abc transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 291.0
HFD2_k127_1136454_9 COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002051 272.0
HFD2_k127_11387_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008475 452.0
HFD2_k127_11387_1 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000003268 267.0
HFD2_k127_11387_2 MlaA lipoprotein K04754 - - 0.000000000000000000000000000000000000000000000000000000000000000000001169 245.0
HFD2_k127_11387_3 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000479 209.0
HFD2_k127_11387_4 Domain of unknown function (DUF4416) - - - 0.00000000000000000000000000000000002163 141.0
HFD2_k127_11387_5 mannose-6-phosphate isomerase K00971 - 2.7.7.13 0.000000000000002858 78.0
HFD2_k127_11387_6 NfeD-like C-terminal, partner-binding K07403 - - 0.0002799 46.0
HFD2_k127_114785_0 phosphorelay signal transduction system K02481,K07713,K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007617 481.0
HFD2_k127_114785_1 PFAM ATP-binding region ATPase domain protein K07709 - 2.7.13.3 0.0000000000000000000000000000000000000000000000005546 184.0
HFD2_k127_1155894_0 Thioesterase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009844 523.0
HFD2_k127_1155894_1 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 326.0
HFD2_k127_1155894_2 GNAT family acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000005038 205.0
HFD2_k127_1155894_3 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K05827,K05844,K14940,K18310 - 6.3.1.17,6.3.2.32,6.3.2.41,6.3.2.43 0.0000000000000000000000000000000000000000000000000002526 187.0
HFD2_k127_1155894_4 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000003933 181.0
HFD2_k127_1155894_5 Protein of unknown function (DUF541) K09807 - - 0.0000000000000000000000000000000000001968 152.0
HFD2_k127_1155894_6 metalloendopeptidase activity K06013 - 3.4.24.84 0.00000000000000002097 93.0
HFD2_k127_1155894_7 lysine biosynthesis protein LysW K05826 - - 0.000000000000002727 76.0
HFD2_k127_115825_0 Molydopterin dinucleotide binding domain K00123,K05299 - 1.17.1.10,1.17.1.9 0.0 1178.0
HFD2_k127_115825_1 PFAM formate nitrite transporter K06212,K21993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 306.0
HFD2_k127_115825_2 Cytochrome c - - - 0.00000000000000000003784 95.0
HFD2_k127_1161076_0 AAA domain K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000423 412.0
HFD2_k127_1161076_1 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003237 385.0
HFD2_k127_1161076_2 Binding-protein-dependent transport system inner membrane component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 359.0
HFD2_k127_1161076_3 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 338.0
HFD2_k127_1161076_4 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.0000000000000003989 90.0
HFD2_k127_1161076_5 CoA-binding domain protein - - - 0.0000000009158 64.0
HFD2_k127_1161076_6 LVIVD repeat - - - 0.00001857 47.0
HFD2_k127_1164270_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 1.383e-211 674.0
HFD2_k127_1164270_1 repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004847 333.0
HFD2_k127_1164270_2 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000004677 84.0
HFD2_k127_1174503_0 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls - - - 0.0000000000000000000000000000000000000000000000000004328 199.0
HFD2_k127_1174503_1 short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000135 73.0
HFD2_k127_1174503_2 PFAM 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) - - - 0.000000003333 69.0
HFD2_k127_1176025_0 COG0145 N-methylhydantoinase A acetone carboxylase, beta subunit K01473 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009408 298.0
HFD2_k127_1176025_1 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000001373 216.0
HFD2_k127_1181905_0 Cytochrome c - - - 8.107e-220 713.0
HFD2_k127_1181905_1 Cytochrome b(N-terminal)/b6/petB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008214 421.0
HFD2_k127_1181905_10 40-residue YVTN family beta-propeller repeat - - - 0.000000000000000000000000000000000000000000001992 180.0
HFD2_k127_1181905_11 Enoyl-(Acyl carrier protein) reductase K21883 - 1.1.1.401 0.0000000000000000000000000000000000413 139.0
HFD2_k127_1181905_12 Class II Aldolase and Adducin N-terminal domain - - - 0.0000000000000000004253 96.0
HFD2_k127_1181905_13 - - - - 0.0000000000001883 74.0
HFD2_k127_1181905_14 Amidohydrolase K10220 - 4.2.1.83 0.0008989 42.0
HFD2_k127_1181905_2 'glutamate synthase K00528,K03388 - 1.18.1.2,1.19.1.1,1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004753 356.0
HFD2_k127_1181905_3 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 321.0
HFD2_k127_1181905_4 Protein of unknown function (DUF3750) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 304.0
HFD2_k127_1181905_5 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003044 285.0
HFD2_k127_1181905_6 ABC transporter, ATP-binding protein K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000001172 254.0
HFD2_k127_1181905_7 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002252 251.0
HFD2_k127_1181905_8 oxidoreductase activity, acting on diphenols and related substances as donors K02636,K03886 - 1.10.9.1 0.0000000000000000000000000000000000000000000000000000000216 201.0
HFD2_k127_1181905_9 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000002469 194.0
HFD2_k127_118899_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 3.589e-204 662.0
HFD2_k127_118899_1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K16874 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001038 289.0
HFD2_k127_118899_2 Phosphoesterase K07095 - - 0.000000000000000000000000000003017 124.0
HFD2_k127_118899_3 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.0000000000000000000001248 109.0
HFD2_k127_118899_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000003632 94.0
HFD2_k127_1191349_0 xanthine dehydrogenase activity K04108 - 1.3.7.9 4.973e-313 977.0
HFD2_k127_1191349_1 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003344 357.0
HFD2_k127_1191349_2 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000001204 228.0
HFD2_k127_1191349_3 AMP-binding enzyme C-terminal domain - - - 0.00000000000001021 76.0
HFD2_k127_1191349_4 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K16874 - - 0.00005869 48.0
HFD2_k127_1195810_0 5-oxoprolinase K01473 - 3.5.2.14 8.802e-211 675.0
HFD2_k127_1195810_1 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 412.0
HFD2_k127_1195810_2 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000859 395.0
HFD2_k127_1215627_0 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051,K15553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001265 276.0
HFD2_k127_1215627_1 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001858 273.0
HFD2_k127_1215627_2 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001008 253.0
HFD2_k127_12325_0 Proposed homoserine kinase K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003869 473.0
HFD2_k127_12325_1 TIGRFAM fructose-1,6-bisphosphatase, class II K02446 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 426.0
HFD2_k127_12325_2 homoserine dehydrogenase K00003 - 1.1.1.3 0.000000004215 63.0
HFD2_k127_1236332_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 632.0
HFD2_k127_1236332_1 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005701 566.0
HFD2_k127_1236332_2 transferase activity, transferring glycosyl groups K02844 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008194,GO:0008610,GO:0008653,GO:0008919,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046401,GO:0046527,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004452 317.0
HFD2_k127_1236332_3 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000007396 188.0
HFD2_k127_1236332_4 PAS fold - - - 0.00000000000000000000000000000000000000000001922 179.0
HFD2_k127_1236332_5 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000228 143.0
HFD2_k127_1236332_6 TRAP transporter, solute receptor (TAXI family K01207,K07080 - 3.2.1.52 0.00000000000000000000000009353 111.0
HFD2_k127_1265473_0 PFAM Carbamoyl-phosphate synthase L chain ATP-binding K01955 - 6.3.5.5 0.0 1510.0
HFD2_k127_1265473_1 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 532.0
HFD2_k127_1265473_2 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000003943 273.0
HFD2_k127_1265473_3 Phosphoesterase K07095 - - 0.000000000000000000000000000000000000000000000000000639 191.0
HFD2_k127_1265473_4 Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000273 168.0
HFD2_k127_1265473_5 COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K12528 - - 0.0002962 43.0
HFD2_k127_127009_0 Required for chromosome condensation and partitioning K03529 - - 2.217e-222 731.0
HFD2_k127_127009_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005329 340.0
HFD2_k127_127009_2 Belongs to the enoyl-CoA hydratase isomerase family K15019 - 4.2.1.116 0.00000000000000000000000000002868 126.0
HFD2_k127_1271617_0 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004832 256.0
HFD2_k127_1271617_1 PFAM Chlorite dismutase - - - 0.00000000000000000000000000000000000000000000000000000000000000006055 225.0
HFD2_k127_1271617_2 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.00000005365 56.0
HFD2_k127_129448_0 NMT1-like family K02051 - - 0.00000000000000000000000008654 119.0
HFD2_k127_129448_1 - - - - 0.0000000000000000000000006636 108.0
HFD2_k127_129448_2 - - - - 0.00000000000005274 78.0
HFD2_k127_129448_3 PFAM Transposase IS200 like K07491 - - 0.0000000424 61.0
HFD2_k127_1295589_0 AraC-like ligand binding domain K00450 - 1.13.11.4 0.00000000000000000000000000000000000000000009561 165.0
HFD2_k127_1295589_1 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000006903 134.0
HFD2_k127_1295589_2 gag-polyprotein putative aspartyl protease - - - 0.000002271 54.0
HFD2_k127_1310893_0 Bacterial protein of unknown function (DUF853) - - - 3.406e-220 688.0
HFD2_k127_1310893_1 COG1228 Imidazolonepropionase and related amidohydrolases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009706 288.0
HFD2_k127_1310893_2 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006725 268.0
HFD2_k127_1310893_3 PFAM Transglycosylase-associated protein - - - 0.00000000000000000000000000002877 122.0
HFD2_k127_1310893_4 - - - - 0.000000000000000000001093 98.0
HFD2_k127_1310893_5 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.000000000000000001119 97.0
HFD2_k127_1310893_6 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.0000000000005299 79.0
HFD2_k127_1322950_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 475.0
HFD2_k127_1322950_1 Aldehyde oxidase and xanthine dehydrogenase K00087,K03520 - 1.17.1.4,1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 468.0
HFD2_k127_1322950_10 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000001163 132.0
HFD2_k127_1322950_11 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000003708 122.0
HFD2_k127_1322950_12 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000003602 116.0
HFD2_k127_1322950_13 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 0.000000000000000000000005039 109.0
HFD2_k127_1322950_14 NMT1-like family - - - 0.00000000004224 75.0
HFD2_k127_1322950_2 ABC-type Fe3 transport system permease component K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 426.0
HFD2_k127_1322950_3 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 404.0
HFD2_k127_1322950_4 Belongs to the UbiD family K03182 - 4.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 335.0
HFD2_k127_1322950_5 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K16874 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001162 275.0
HFD2_k127_1322950_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002443 269.0
HFD2_k127_1322950_7 xanthine dehydrogenase activity K11178 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000004536 246.0
HFD2_k127_1322950_8 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS-like protein K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000008854 185.0
HFD2_k127_1322950_9 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000002213 133.0
HFD2_k127_1339492_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 542.0
HFD2_k127_1339492_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001163 306.0
HFD2_k127_1339492_2 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.00000000000000000000000000000000000000000000000000000000000002282 220.0
HFD2_k127_1339492_3 - - - - 0.000000000000000000000000000000000000003097 149.0
HFD2_k127_1339492_4 response regulator K02490 - - 0.000000000000000002757 89.0
HFD2_k127_1354029_0 Domain of unknown function (DUF3459) K01236 - 3.2.1.141 3.949e-261 822.0
HFD2_k127_1354029_1 High confidence in function and specificity - - - 1.053e-260 816.0
HFD2_k127_1354029_2 Pfam:KaiC K08482 - - 1.331e-209 662.0
HFD2_k127_1354029_3 Histidine kinase K14986 - 2.7.13.3 0.000000000000000000000000000000000000000000003951 181.0
HFD2_k127_1354029_4 KaiB K08481 - - 0.00000000000000000000000000000000000007253 144.0
HFD2_k127_1369148_0 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000005086 234.0
HFD2_k127_1369148_1 Amidohydrolase K03392 - 4.1.1.45 0.00000000000000000000000000000000000006086 155.0
HFD2_k127_1369148_2 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K01838 - 5.4.2.6 0.0000000000000000000000000000000004461 139.0
HFD2_k127_1369148_3 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000004458 116.0
HFD2_k127_1369148_4 PKD domain containing protein - - - 0.00000000000000003292 96.0
HFD2_k127_1369148_5 Putative phosphatase (DUF442) - - - 0.000000000000001751 84.0
HFD2_k127_1378106_0 PFAM Hydantoinase oxoprolinase K01473,K10855 - 3.5.2.14,6.4.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004955 508.0
HFD2_k127_1378106_1 Hydantoinase B/oxoprolinase K01474,K10854 - 3.5.2.14,6.4.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004339 309.0
HFD2_k127_1378106_2 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000000000000000000002491 157.0
HFD2_k127_1378106_3 - - - - 0.000000000000000000000000000002291 121.0
HFD2_k127_1378106_4 light absorption - - - 0.0000000000000004033 84.0
HFD2_k127_1380533_0 Aldehyde oxidase and xanthine dehydrogenase K00087,K03520 - 1.17.1.4,1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004324 288.0
HFD2_k127_1380533_1 Glutathione S-transferase, N-terminal domain - - - 0.00000000000000000001208 93.0
HFD2_k127_1407601_0 Belongs to the UPF0255 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006508 280.0
HFD2_k127_1407601_1 NMT1/THI5 like K02051 - - 0.000001147 59.0
HFD2_k127_142513_0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) K01214 - 3.2.1.68 0.0 1127.0
HFD2_k127_142513_1 Maltooligosyl trehalose synthase K06044 - 5.4.99.15 0.0 1084.0
HFD2_k127_142513_2 Alpha-amylase domain K05343 - 3.2.1.1,5.4.99.16 0.0 1022.0
HFD2_k127_142513_3 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 5.333e-312 967.0
HFD2_k127_142513_4 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 1.581e-273 858.0
HFD2_k127_142513_5 Domain of unknown function (DUF3459) K00700,K01236 - 2.4.1.18,3.2.1.141 3.065e-230 729.0
HFD2_k127_142513_6 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000217 229.0
HFD2_k127_1426250_0 COG1042 Acyl-CoA synthetase (NDP forming) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009054 403.0
HFD2_k127_1426250_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001982 264.0
HFD2_k127_1426250_2 NMT1-like family K02051,K15553 - - 0.00000000005638 73.0
HFD2_k127_1426250_3 NMT1-like family K02051 - - 0.000007929 58.0
HFD2_k127_1426602_0 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006247 421.0
HFD2_k127_1426602_1 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.000000000000000000000000000000000000000000000000000003819 196.0
HFD2_k127_1428690_0 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 416.0
HFD2_k127_1428690_1 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009816 378.0
HFD2_k127_1428690_2 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009261 332.0
HFD2_k127_1428690_3 Rhodanese-like domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000003326 238.0
HFD2_k127_1428690_4 alpha/beta hydrolase fold K01253 - 3.3.2.9 0.000000000000000000000000000000000000000000000000000000000000007842 224.0
HFD2_k127_1428690_5 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000000000000000000005785 194.0
HFD2_k127_1428690_6 ubiE/COQ5 methyltransferase family K00570 - 2.1.1.17,2.1.1.71 0.0000000000000000000000000000000000000000000000004836 182.0
HFD2_k127_1428690_7 mttA/Hcf106 family K03116 - - 0.00000000000001494 75.0
HFD2_k127_1428690_8 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.00000000002473 69.0
HFD2_k127_143157_0 DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001724 260.0
HFD2_k127_143157_1 Transposase K07483 - - 0.000000000000000000000000003764 115.0
HFD2_k127_14354_0 Belongs to the MlaE permease family K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004025 407.0
HFD2_k127_14354_1 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 344.0
HFD2_k127_14354_2 Mammalian cell entry related domain protein K02067,K06192 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002257 284.0
HFD2_k127_14354_3 Protein conserved in bacteria K18480 - - 0.0000000000000000000000000000000000000000000000001973 184.0
HFD2_k127_14354_4 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000006671 113.0
HFD2_k127_14354_5 Glyoxalase-like domain - - - 0.000002359 57.0
HFD2_k127_1437741_0 Carbohydrate phosphorylase K00688,K16153 - 2.4.1.1,2.4.1.11 0.00000000000000000000000000000000000000000000008237 170.0
HFD2_k127_1437741_1 tungstate binding K02020 - - 0.0000000000000000000000000000000000000000000004917 175.0
HFD2_k127_1437741_2 O-methyltransferase - - - 0.0000000000008363 78.0
HFD2_k127_1437741_3 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0000000003749 62.0
HFD2_k127_1437741_4 Histidine kinase - - - 0.0000001066 62.0
HFD2_k127_144295_0 Catalyzes the conversion of feruloyl-CoA to vanillin and acetyl-CoA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 354.0
HFD2_k127_144295_1 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000004429 89.0
HFD2_k127_144295_2 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0001499 45.0
HFD2_k127_145844_0 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs - - - 6.713e-227 734.0
HFD2_k127_145844_1 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 531.0
HFD2_k127_145844_2 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000004729 200.0
HFD2_k127_1459514_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 4.817e-211 675.0
HFD2_k127_1462785_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 539.0
HFD2_k127_1462785_1 Belongs to the UbiD family K16874 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 330.0
HFD2_k127_1462785_2 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000123 285.0
HFD2_k127_1462785_3 Bacterial sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000007031 202.0
HFD2_k127_1462785_4 PFAM RNA-directed DNA polymerase (reverse transcriptase) - - - 0.00000000000000000000000000000001775 130.0
HFD2_k127_1462785_5 glycosyl transferase, family 2 - - - 0.00000000000000000000134 105.0
HFD2_k127_1462785_6 bicarbonate transporter, IctB family K18814 - - 0.00000000000000008607 93.0
HFD2_k127_147131_0 NADH oxidase K00219 - 1.3.1.34 1.521e-247 780.0
HFD2_k127_147131_1 amidohydrolase K03392,K07045 - 4.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005024 440.0
HFD2_k127_147131_2 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K16874 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005981 314.0
HFD2_k127_147131_3 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 0.000000000000000000000000000000000000000000000000000000005701 205.0
HFD2_k127_1471666_0 succinate dehydrogenase, flavoprotein subunit K00239 GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363 1.3.5.1,1.3.5.4 6.869e-288 895.0
HFD2_k127_1471666_1 Succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000708 397.0
HFD2_k127_1471666_2 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004939 291.0
HFD2_k127_1471666_3 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679,K01744 - 4.2.1.2,4.3.1.1 0.0000000000000000000000155 101.0
HFD2_k127_1471666_4 Ferredoxin - - - 0.0000000000000000007456 90.0
HFD2_k127_1472070_0 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005961 264.0
HFD2_k127_1472070_1 Protein of unknown function (DUF1152) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000218 251.0
HFD2_k127_1472070_2 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000239 204.0
HFD2_k127_1472070_3 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000004597 188.0
HFD2_k127_1472070_4 Ndr family K01607 - 4.1.1.44 0.00000009868 60.0
HFD2_k127_1475224_0 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000000000000000000000000000000000000001527 204.0
HFD2_k127_1475224_1 Asp/Glu/Hydantoin racemase K01799 - 5.2.1.1 0.000000000000000000000000003091 120.0
HFD2_k127_1475224_2 NMT1-like family K02051 - - 0.00000000000000000001129 102.0
HFD2_k127_1478479_0 Ion channel K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009012 326.0
HFD2_k127_1478479_2 Transposase K07491 - - 0.0000000000000000003475 90.0
HFD2_k127_1478479_3 Ornithine cyclodeaminase K01750 - 4.3.1.12 0.0000000002512 63.0
HFD2_k127_152980_0 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003244 297.0
HFD2_k127_152980_1 Carboxylesterase family K01432 - 3.5.1.9 0.0000000000000000000000000000000000000000000000000000000000329 213.0
HFD2_k127_152980_2 Iron-binding zinc finger CDGSH type - - - 0.0000000000001503 75.0
HFD2_k127_1578502_0 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 555.0
HFD2_k127_1578502_1 Cytochrome c K17230 - - 0.000000000000000000000000000000000000000000000000000000009079 208.0
HFD2_k127_1578972_0 Aldo Keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000865 326.0
HFD2_k127_1578972_1 TraB family K09973 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000303 252.0
HFD2_k127_1578972_2 SelR domain K07305,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000001391 228.0
HFD2_k127_1578972_3 GTP binding K09767 GO:0000049,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0009987,GO:0017076,GO:0019001,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033554,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000005798 194.0
HFD2_k127_1578972_4 thiolester hydrolase activity - - - 0.0000000000000000000000000000000000000000000759 165.0
HFD2_k127_1578972_5 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 0.000000000000000000000002863 105.0
HFD2_k127_1578972_6 acetoin utilization protein K04767 - - 0.000000000000000000001964 100.0
HFD2_k127_1578972_7 nitrite reductase [NAD(P)H] activity K00363 - 1.7.1.15 0.000000000007499 69.0
HFD2_k127_1578972_8 aldo keto reductase - - - 0.0000000342 56.0
HFD2_k127_158524_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005954 282.0
HFD2_k127_158524_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K01719,K13542 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107,4.1.1.37,4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000002325 222.0
HFD2_k127_158524_2 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000001431 223.0
HFD2_k127_1585281_0 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000001105 211.0
HFD2_k127_1585281_1 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000003194 164.0
HFD2_k127_1585281_2 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000001659 160.0
HFD2_k127_1585281_3 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000002542 153.0
HFD2_k127_1585281_4 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000005349 153.0
HFD2_k127_1585281_5 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000001205 97.0
HFD2_k127_1585281_6 thiamine-containing compound biosynthetic process K02051 - - 0.0000002343 60.0
HFD2_k127_163096_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000557 208.0
HFD2_k127_163096_1 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000001785 190.0
HFD2_k127_163096_2 F420H(2)-dependent quinone reductase - - - 0.000000000000000000004947 100.0
HFD2_k127_163096_3 Mut7-C RNAse domain K00525 - 1.17.4.1 0.000001007 54.0
HFD2_k127_1668268_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 591.0
HFD2_k127_1668268_1 PFAM glycosyl transferase family 39 - - - 0.00000000000000000000000000000000000000000000000000000000000005802 235.0
HFD2_k127_1668268_2 PFAM asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000001155 159.0
HFD2_k127_1668268_3 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000005155 66.0
HFD2_k127_1668268_4 Integrase core domain - - - 0.00000023 55.0
HFD2_k127_1672158_0 Protein of unknown function (DUF1343) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 322.0
HFD2_k127_1672158_1 membrane - - - 0.0000000000000000000000000000000000000000000000000000002661 199.0
HFD2_k127_1672158_2 Phenylacetate-CoA oxygenase K02609 - 1.14.13.149 0.00000000000000000000000000000000001602 146.0
HFD2_k127_1672158_3 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000461 73.0
HFD2_k127_171178_0 Endopeptidase La K04076 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007768 618.0
HFD2_k127_171178_1 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000001561 106.0
HFD2_k127_171178_2 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000001108 54.0
HFD2_k127_171178_3 Protein of unknown function (DUF2934) - - - 0.0006253 47.0
HFD2_k127_1719747_0 Binding-protein-dependent transport system inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 423.0
HFD2_k127_1719747_1 Peptidase dimerisation domain K13049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004737 328.0
HFD2_k127_1719747_2 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000002819 181.0
HFD2_k127_1719747_3 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000003209 165.0
HFD2_k127_1719747_4 TIGRFAM acetylornithine deacetylase or succinyl- diaminopimelate desuccinylase K01439 - 3.5.1.18 0.0000000000000000000000442 112.0
HFD2_k127_172458_0 aconitate hydratase K01681 - 4.2.1.3 0.0 1168.0
HFD2_k127_172458_1 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000005343 183.0
HFD2_k127_172458_2 Protein of unknown function (DUF2914) - - - 0.00000000000000000000000000000000000006829 155.0
HFD2_k127_172458_3 Zn peptidase - - - 0.000000000000000000000000000000002155 145.0
HFD2_k127_172458_4 Elongator protein 3 MiaB NifB - - - 0.00009613 48.0
HFD2_k127_172458_5 long-chain fatty acid transporting porin activity - - - 0.0001724 51.0
HFD2_k127_1728214_0 N-acetyl-gamma-glutamyl-phosphate reductase activity K00145,K05829 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 520.0
HFD2_k127_1728214_1 N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity K00821,K05830 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007054 511.0
HFD2_k127_1728214_2 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930,K01438,K05828,K05831 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8,3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005583 342.0
HFD2_k127_1728214_3 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K05827,K05844,K14940,K18310 - 6.3.1.17,6.3.2.32,6.3.2.41,6.3.2.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008929 336.0
HFD2_k127_1728214_4 cellular modified histidine biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000637 263.0
HFD2_k127_1758449_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07812 - 1.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000463 498.0
HFD2_k127_1758449_1 Uncharacterised protein family UPF0066 - - - 0.0000000000000000000000000000000000000000000000000000000002193 206.0
HFD2_k127_1758449_2 Transporter, major facilitator family protein K08369 - - 0.000000005287 59.0
HFD2_k127_1764949_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 446.0
HFD2_k127_1764949_1 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008441 289.0
HFD2_k127_1764949_2 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000000000000003717 219.0
HFD2_k127_1764949_3 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000002604 166.0
HFD2_k127_1764949_4 methyltransferase activity - - - 0.000000000000000000000000000000000000000003037 160.0
HFD2_k127_1764949_5 membrane transporter protein K07090 - - 0.000000000000000000000000001112 122.0
HFD2_k127_1780759_0 Conserved carboxylase domain K01571 - 4.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005185 302.0
HFD2_k127_1780759_1 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.0000000000001971 81.0
HFD2_k127_1780759_2 Transposase domain (DUF772) - - - 0.000000004753 60.0
HFD2_k127_1784409_0 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 559.0
HFD2_k127_1784409_1 FAD linked oxidases, C-terminal domain K00803 - 2.5.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004445 297.0
HFD2_k127_1784409_2 PFAM Peptidase M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000003031 247.0
HFD2_k127_1784409_3 PFAM ribonuclease H K03469,K06864 - 3.1.26.4 0.000000000000000000000000000000000000004592 150.0
HFD2_k127_1784409_4 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.000000000000000000000000000000007901 132.0
HFD2_k127_1784409_5 C4-type zinc ribbon domain K07164 - - 0.000000000000000000000000000123 124.0
HFD2_k127_1784409_6 SPTR Transposase, IS204 IS1001 IS1096 IS1165 family protein K07485 - - 0.000000006951 56.0
HFD2_k127_1784409_8 PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein - - - 0.00002939 48.0
HFD2_k127_1786875_0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01581 - 4.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003078 329.0
HFD2_k127_1790190_0 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.000000000000000000000000006322 113.0
HFD2_k127_1790190_1 transcriptional regulator K09017 - - 0.000000000000009593 76.0
HFD2_k127_1790312_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 481.0
HFD2_k127_1790312_1 Component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000003971 244.0
HFD2_k127_1790836_0 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 6.533e-247 773.0
HFD2_k127_1790836_1 PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein K01739,K01761 - 2.5.1.48,4.4.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007366 469.0
HFD2_k127_1790836_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01697 - 4.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 458.0
HFD2_k127_1793542_0 PFAM aminotransferase class V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005111 436.0
HFD2_k127_1793542_1 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000001623 62.0
HFD2_k127_1793542_2 energy transducer activity K03832 - - 0.000002132 59.0
HFD2_k127_1800089_0 Biotin-lipoyl like K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 383.0
HFD2_k127_1800089_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007838 334.0
HFD2_k127_1800089_2 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006882 243.0
HFD2_k127_1800089_3 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000001421 253.0
HFD2_k127_1808168_0 Surface antigen K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009733 353.0
HFD2_k127_1808168_1 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000000415 86.0
HFD2_k127_1841121_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004619 623.0
HFD2_k127_1841121_1 amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 341.0
HFD2_k127_1841121_2 PFAM Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000000008405 212.0
HFD2_k127_1841121_3 4,5-dihydroxyphthalate decarboxylase K04102 - 4.1.1.55 0.00000000000000000000000000000000000007595 154.0
HFD2_k127_1841121_4 Histidine kinase K07681,K11617 - 2.7.13.3 0.00000000000000000000000006839 115.0
HFD2_k127_1841121_5 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000004053 110.0
HFD2_k127_1841121_6 response regulator receiver - - - 0.000000000000000001778 98.0
HFD2_k127_184739_0 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005258 409.0
HFD2_k127_184739_1 TIGRFAM LPPG domain K11212 - 2.7.8.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008163 303.0
HFD2_k127_184739_2 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.00000000000000000000000000000000000000000000000000000000000000000005543 239.0
HFD2_k127_184739_3 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.0000000000000000000008466 104.0
HFD2_k127_184739_4 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00002705 49.0
HFD2_k127_1857086_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 567.0
HFD2_k127_1857086_1 Na+-transporting oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 522.0
HFD2_k127_1857086_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000001161 239.0
HFD2_k127_1857086_3 photoreceptor activity K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000007627 209.0
HFD2_k127_1857086_4 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000004114 173.0
HFD2_k127_1857086_5 - - - - 0.00000000000000000003473 93.0
HFD2_k127_1857086_6 Glycine cleavage H-protein - - - 0.0000000000000008292 81.0
HFD2_k127_1857178_0 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 502.0
HFD2_k127_1857178_1 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 499.0
HFD2_k127_1857178_2 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 462.0
HFD2_k127_1857178_3 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000002014 193.0
HFD2_k127_1857178_4 Deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000002629 174.0
HFD2_k127_1878517_0 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 323.0
HFD2_k127_1878517_1 FAD binding domain - - - 0.00000000000000000000000000000000000000000241 163.0
HFD2_k127_1884010_0 ABC transporter K06147,K18890 - - 2.301e-242 769.0
HFD2_k127_1884010_1 ABC transporter transmembrane region K06147,K18889 - - 3.874e-197 633.0
HFD2_k127_1884010_10 Protein of unknown function (DUF1800) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 403.0
HFD2_k127_1884010_11 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 359.0
HFD2_k127_1884010_12 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 354.0
HFD2_k127_1884010_13 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 334.0
HFD2_k127_1884010_14 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009797 304.0
HFD2_k127_1884010_15 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000008123 188.0
HFD2_k127_1884010_16 Fibronectin type 3 domain - - - 0.0000000000004146 77.0
HFD2_k127_1884010_17 aminopeptidase N - - - 0.00000002566 65.0
HFD2_k127_1884010_2 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019904,GO:0022607,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043335,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 2.418e-194 616.0
HFD2_k127_1884010_3 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006961 610.0
HFD2_k127_1884010_4 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 593.0
HFD2_k127_1884010_5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003761 549.0
HFD2_k127_1884010_6 Argininosuccinate lyase C-terminal K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 546.0
HFD2_k127_1884010_7 TIGRFAM acetylornithine and succinylornithine K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 505.0
HFD2_k127_1884010_8 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 444.0
HFD2_k127_1884010_9 Amino acid kinase family K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 396.0
HFD2_k127_1915383_0 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000009126 161.0
HFD2_k127_1915383_1 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000164 116.0
HFD2_k127_1915383_2 Putative zinc-finger - - - 0.00007714 53.0
HFD2_k127_1915383_3 Protein of unknown function (DUF3106) - - - 0.0005125 48.0
HFD2_k127_19157_0 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.00000000000000000000000000000000000000000000000000000001493 208.0
HFD2_k127_19157_1 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000002491 157.0
HFD2_k127_19157_2 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000003355 111.0
HFD2_k127_1939753_0 NnrU protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000006588 241.0
HFD2_k127_1939753_1 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000000000000000001636 143.0
HFD2_k127_1957623_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 572.0
HFD2_k127_1957623_1 Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 564.0
HFD2_k127_1957623_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005577 383.0
HFD2_k127_1957623_3 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000008816 249.0
HFD2_k127_1957623_4 cyclic nucleotide binding K07058,K14266 - 1.14.19.9 0.000000000000000000000000000000000000000000000000000001583 198.0
HFD2_k127_1957623_5 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000179 169.0
HFD2_k127_1957623_6 cyclic nucleotide binding K07058,K14266 - 1.14.19.9 0.0000000000000000000000000000000003387 134.0
HFD2_k127_1957623_7 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03749 - - 0.00000007205 63.0
HFD2_k127_1957623_8 PFAM Integrase catalytic region K07497 - - 0.0000957 46.0
HFD2_k127_1959660_0 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 310.0
HFD2_k127_1959660_1 COG0747 ABC-type dipeptide transport system, periplasmic component K02035 - - 0.00000000000000000000000002453 110.0
HFD2_k127_1959660_2 NMT1-like family K02051 - - 0.00000000000000517 86.0
HFD2_k127_1964316_0 Multidrug ABC transporter ATP-binding protein K01990 - - 1.283e-205 651.0
HFD2_k127_1964316_1 Biotin-lipoyl like K01993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003741 387.0
HFD2_k127_1964316_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585,K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 301.0
HFD2_k127_1964316_3 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003271 246.0
HFD2_k127_1964316_4 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.00000000000000000007686 94.0
HFD2_k127_1974545_0 FtsX-like permease family K02004 - - 3.817e-206 669.0
HFD2_k127_1974545_1 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 285.0
HFD2_k127_1974545_2 GDSL-like Lipase/Acylhydrolase family K10804 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000001181 256.0
HFD2_k127_1974545_3 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.00000000000000000000000000000000000000000000000000344 186.0
HFD2_k127_1974545_4 Cytidylate kinase-like family - - - 0.00000000000000000000000000000000004735 145.0
HFD2_k127_1979009_0 Zn-dependent hydrolases of the - - - 0.000000000000000000000000000000000005765 147.0
HFD2_k127_1979009_1 NMT1-like family K02051 - - 0.0000000000002885 81.0
HFD2_k127_1979009_2 Glycine zipper 2TM domain - - - 0.00008055 49.0
HFD2_k127_1979009_3 thiamine-containing compound biosynthetic process K02051 - - 0.0002564 48.0
HFD2_k127_1992888_0 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001197 267.0
HFD2_k127_1992888_1 PFAM binding-protein-dependent transport systems inner membrane component K02034,K15582 - - 0.000000000000000000000000000000000000000000000000000000000136 213.0
HFD2_k127_1992888_2 ABC transporter substrate-binding protein K02035 - - 0.00000000000000000000000000000000000000000000000000001261 209.0
HFD2_k127_1997097_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 353.0
HFD2_k127_1997097_1 - - - - 0.00000000000000000000000117 104.0
HFD2_k127_1997097_2 Transcriptional regulator - - - 0.00001551 48.0
HFD2_k127_199815_0 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 456.0
HFD2_k127_199815_1 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002556 271.0
HFD2_k127_199815_10 NMT1-like family - - - 0.0000000000000000000007231 108.0
HFD2_k127_199815_11 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000002842 82.0
HFD2_k127_199815_2 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004473 268.0
HFD2_k127_199815_3 Protein of unknown function (DUF423) - - - 0.0000000000000000000000000000000000000000000004494 169.0
HFD2_k127_199815_4 Binding-protein-dependent transport system inner membrane component K02050,K15552 - - 0.00000000000000000000000000000000000000000001433 173.0
HFD2_k127_199815_5 PFAM Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000002525 171.0
HFD2_k127_199815_6 deacetylase K22278 - 3.5.1.104 0.000000000000000000000000000000000000003872 158.0
HFD2_k127_199815_7 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000000000000000000001304 157.0
HFD2_k127_199815_8 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000000000000000004584 144.0
HFD2_k127_199815_9 oxidation-reduction process - - - 0.000000000000000000000518 101.0
HFD2_k127_2006049_0 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009294 341.0
HFD2_k127_2006049_1 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007996 314.0
HFD2_k127_2006049_2 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000005583 210.0
HFD2_k127_2006049_3 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000067 192.0
HFD2_k127_2006049_4 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000405 176.0
HFD2_k127_2006049_5 Ribosomal protein L11 methyltransferase K02687 - - 0.00000000000000000000000000000000000000000653 165.0
HFD2_k127_2006049_6 RDD family - - - 0.0000000000003178 79.0
HFD2_k127_2006049_7 - - - - 0.0000006155 51.0
HFD2_k127_2024689_0 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007874 604.0
HFD2_k127_2024689_1 TIGRFAM 40-residue YVTN family beta-propeller repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 456.0
HFD2_k127_2024689_2 YCII-related domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001089 232.0
HFD2_k127_2024689_3 Protein conserved in bacteria K04750 - - 0.0000000000000000000000000000000000000000000000000000000003741 205.0
HFD2_k127_2024689_4 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000004333 190.0
HFD2_k127_2024689_5 SnoaL-like domain K04750 - - 0.0000000000000000000000000000000000000000000000003791 179.0
HFD2_k127_2024689_6 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000287 76.0
HFD2_k127_2024689_7 Putative DNA-binding domain - - - 0.000000000000005584 83.0
HFD2_k127_2024689_8 Putative DNA-binding domain - - - 0.0000005471 52.0
HFD2_k127_2026714_0 PFAM Glucose Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003848 389.0
HFD2_k127_2026714_1 Conserved carboxylase domain K01571 - 4.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000576 367.0
HFD2_k127_2026714_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009574 362.0
HFD2_k127_2034276_0 COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000395 263.0
HFD2_k127_2034276_1 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000003997 238.0
HFD2_k127_2034276_2 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000003116 93.0
HFD2_k127_2034276_3 TIGRFAM CitB domain protein K13795 - - 0.00000000000001659 74.0
HFD2_k127_2034401_0 Enoyl-CoA hydratase/isomerase K18383 - 4.1.2.41,4.2.1.101 0.00000000000000000000000000008909 126.0
HFD2_k127_2034401_1 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000002684 97.0
HFD2_k127_2034401_2 Protein of unknown function (DUF1015) - - - 0.0000000000000003401 80.0
HFD2_k127_203791_0 Alpha amylase, C-terminal all-beta domain K00700 - 2.4.1.18 1.2e-322 994.0
HFD2_k127_203791_1 VIT family - - - 0.00000000000000000000000000001045 121.0
HFD2_k127_203791_2 - - - - 0.00000000000000000000000000005161 120.0
HFD2_k127_2049381_0 CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 435.0
HFD2_k127_2049381_1 PUCC protein - - - 0.00000000000000000000000004194 122.0
HFD2_k127_2049381_2 5TMR of 5TMR-LYT K07697 - 2.7.13.3 0.0000000000004697 80.0
HFD2_k127_2049381_3 4,5-dihydroxyphthalate decarboxylase - - - 0.000006539 57.0
HFD2_k127_2049381_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K11527 - 2.7.13.3 0.00001813 56.0
HFD2_k127_2052004_0 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit - - - 0.000000000000000000000000000000000000000002656 166.0
HFD2_k127_2052004_1 Dehydrogenase E1 component K00166 GO:0003674,GO:0003824,GO:0003826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006520,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008677,GO:0009056,GO:0009058,GO:0009063,GO:0009081,GO:0009083,GO:0009108,GO:0009110,GO:0009267,GO:0009314,GO:0009416,GO:0009605,GO:0009628,GO:0009642,GO:0009646,GO:0009743,GO:0009744,GO:0009987,GO:0009991,GO:0010033,GO:0015939,GO:0015940,GO:0016053,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0017086,GO:0019752,GO:0031667,GO:0031668,GO:0031669,GO:0031974,GO:0032787,GO:0032991,GO:0033554,GO:0034285,GO:0034641,GO:0042221,GO:0042364,GO:0042398,GO:0042594,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043604,GO:0043617,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046395,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0055114,GO:0070013,GO:0071496,GO:0071704,GO:0072330,GO:0098798,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901700 1.2.4.4 0.0000000000000000000000000000000000004913 152.0
HFD2_k127_2082474_0 MmgE/PrpD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 363.0
HFD2_k127_2082474_1 Protein involved in propionate catabolism - - - 0.00000000000000000000000000000000000005352 149.0
HFD2_k127_2086854_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.00000000000000000000000000000000000000000000000000000000000000000007695 249.0
HFD2_k127_2090021_0 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009758 560.0
HFD2_k127_2090021_1 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 499.0
HFD2_k127_2090021_2 Glycoprotease family K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004451 368.0
HFD2_k127_2090021_3 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 308.0
HFD2_k127_2090021_4 Transmembrane secretion effector K08225 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 309.0
HFD2_k127_2090021_5 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000003171 256.0
HFD2_k127_2090021_6 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000001187 230.0
HFD2_k127_2090021_7 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000002268 204.0
HFD2_k127_2091840_0 Carbon-nitrogen hydrolase K11206 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002587 252.0
HFD2_k127_2091840_1 High-affinity Fe2 Pb2 permease K07243 - - 0.00000000000000000000000000000000000000000000000000000000000000000001969 250.0
HFD2_k127_2091840_2 ABC-type phosphate phosphonate transport system, periplasmic component K02044 - - 0.000000000000000000000000000000000000000000000000000000000116 215.0
HFD2_k127_2091840_3 phosphonate ABC transporter, inner membrane subunit K02042 - - 0.00000000000000000000000000000000000000000000000000111 192.0
HFD2_k127_2091840_4 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000000000000000003095 188.0
HFD2_k127_2091840_5 FeoA K01356,K03709 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005506,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006355,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009058,GO:0009237,GO:0009712,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0016151,GO:0018958,GO:0019184,GO:0019219,GO:0019222,GO:0019290,GO:0019540,GO:0019748,GO:0030145,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0044550,GO:0045892,GO:0045934,GO:0046870,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0050897,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.00000000000000000000000000000000000000000002258 169.0
HFD2_k127_2091840_6 ABC transporter K02041 - 3.6.3.28 0.0000000000000000000000000000000000000000003709 170.0
HFD2_k127_2093117_0 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000005394 259.0
HFD2_k127_2093117_1 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000009817 242.0
HFD2_k127_2093117_2 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain K03520 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000005513 237.0
HFD2_k127_2093117_3 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000008537 239.0
HFD2_k127_2093117_4 PFAM Transposase IS200 like K07491 - - 0.00000000000000000000000000000000007023 139.0
HFD2_k127_2093117_5 phosphorelay signal transduction system - - - 0.000000000000006917 81.0
HFD2_k127_2093117_6 Transposase K07494 - - 0.00007302 46.0
HFD2_k127_2093117_7 Transposase K07491 - - 0.00009159 48.0
HFD2_k127_2096504_0 ATPase associated with various cellular activities, AAA_5 K02584 - - 2.355e-220 702.0
HFD2_k127_2096504_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 1.943e-212 673.0
HFD2_k127_2096504_2 PFAM cell divisionFtsK SpoIIIE K03466 - - 2.418e-207 668.0
HFD2_k127_2096504_3 Uncharacterized protein family UPF0004 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002673 463.0
HFD2_k127_2096504_4 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000205 183.0
HFD2_k127_2096504_5 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000000000000008068 176.0
HFD2_k127_2096504_6 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000000001195 112.0
HFD2_k127_2096504_7 - - - - 0.0000000000000000009148 87.0
HFD2_k127_2096504_8 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.000000000000000009214 92.0
HFD2_k127_2097309_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00122,K00335 - 1.17.1.9,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 481.0
HFD2_k127_2097309_1 glutamate--cysteine ligase K01919 - 6.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005697 409.0
HFD2_k127_2097309_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007425 397.0
HFD2_k127_2097309_3 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000823 304.0
HFD2_k127_2097309_4 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000009893 78.0
HFD2_k127_2097309_5 formate dehydrogenase (NAD+) activity - - - 0.00000000000003301 73.0
HFD2_k127_2097309_6 - - - - 0.0009721 46.0
HFD2_k127_2100919_0 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate K01612 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044464 4.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 513.0
HFD2_k127_2100919_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate - - - 0.00000000000000000000000000000000000000001166 154.0
HFD2_k127_2100919_4 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000001728 120.0
HFD2_k127_2100919_5 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.000000000000000000005068 105.0
HFD2_k127_2100919_6 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.000000000000000005524 91.0
HFD2_k127_2106344_0 COG2133 Glucose sorbosone dehydrogenases K21430 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 375.0
HFD2_k127_2106344_1 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002821 282.0
HFD2_k127_2106344_2 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.000000000000000000000000000000000000000000000000005788 188.0
HFD2_k127_2106344_3 Reverse transcriptase (RNA-dependent DNA polymerase) K00986 - 2.7.7.49 0.000000000000000000000000000007873 120.0
HFD2_k127_2106344_4 Serine aminopeptidase, S33 K06889 - - 0.0000000000000000000000003736 116.0
HFD2_k127_2106344_5 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.0000000000000000000001641 101.0
HFD2_k127_2106344_6 PKD domain containing protein - - - 0.000000000000003935 89.0
HFD2_k127_2106344_7 Helix-turn-helix domain - - - 0.000001704 52.0
HFD2_k127_2111396_0 Ion channel K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 401.0
HFD2_k127_2111396_1 endonuclease III K01247 - 3.2.2.21 0.00000000000000001883 82.0
HFD2_k127_2111396_2 - - - - 0.000000001144 68.0
HFD2_k127_2136468_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 7.613e-248 772.0
HFD2_k127_2136468_2 ATP synthase alpha/beta chain, C terminal domain K02111 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 462.0
HFD2_k127_2136468_3 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008176 341.0
HFD2_k127_2136468_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004653 285.0
HFD2_k127_2136468_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000006508 130.0
HFD2_k127_213923_0 MMPL family K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000001475 234.0
HFD2_k127_213923_1 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000002551 91.0
HFD2_k127_213923_2 Amidohydrolase K07045 - - 0.0000000008293 65.0
HFD2_k127_2140633_0 Transposase domain (DUF772) K07487 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 469.0
HFD2_k127_2140633_1 - - - - 0.0001136 52.0
HFD2_k127_2224964_0 Beta-eliminating lyase K01668 - 4.1.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 317.0
HFD2_k127_2224964_1 AMP-binding enzyme K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002343 287.0
HFD2_k127_2224964_2 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000199 227.0
HFD2_k127_2224964_3 KR domain - - - 0.0000000000000000000000000000000000000000000000000002474 199.0
HFD2_k127_2224964_4 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000001323 168.0
HFD2_k127_2224964_5 CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000000000003981 130.0
HFD2_k127_2224964_6 Belongs to the Nudix hydrolase family - - - 0.000000000000000000000000000007849 124.0
HFD2_k127_2224964_7 SMART extracellular solute-binding protein, family 3 K02030 - - 0.00000000004998 64.0
HFD2_k127_224039_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 519.0
HFD2_k127_224039_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 364.0
HFD2_k127_224039_2 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005977 296.0
HFD2_k127_224039_3 ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 292.0
HFD2_k127_224039_4 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000007517 177.0
HFD2_k127_224039_5 Yqey-like protein K09117 - - 0.000000000000000000000000000000005929 133.0
HFD2_k127_224039_6 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000002248 94.0
HFD2_k127_224039_7 PFAM Colicin V production protein K03558 - - 0.0000000000001221 78.0
HFD2_k127_2240859_0 PFAM Formylglycine-generating sulfatase enzyme K18912 - 1.14.99.50 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003052 497.0
HFD2_k127_2240859_1 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 318.0
HFD2_k127_2240859_2 PFAM Major Facilitator Superfamily K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001848 269.0
HFD2_k127_2240859_3 beta-N-acetylglucosaminidase K01197,K15719 GO:0003674,GO:0003824,GO:0004553,GO:0004563,GO:0005488,GO:0005515,GO:0005975,GO:0006464,GO:0006517,GO:0006807,GO:0008150,GO:0008152,GO:0009100,GO:0009987,GO:0015929,GO:0016231,GO:0016787,GO:0016798,GO:0019538,GO:0030246,GO:0036211,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901135,GO:1901564 2.3.1.48,3.2.1.169,3.2.1.35 0.0000000000000000000000000000000000000000002297 170.0
HFD2_k127_2250084_0 Periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006747 299.0
HFD2_k127_2250084_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000142 246.0
HFD2_k127_2250084_2 MatE - - - 0.00000000000000000000000000000000000000000000000000000000000000000843 241.0
HFD2_k127_2250084_3 Yip1 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000008381 224.0
HFD2_k127_2250084_4 Tetratricopeptide repeat - - - 0.00000000255 61.0
HFD2_k127_2250084_5 methyltransferase - - - 0.00000004258 64.0
HFD2_k127_2275026_0 PFAM Conserved carboxylase region K01571,K01960 - 4.1.1.3,6.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005265 560.0
HFD2_k127_2275026_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000001603 240.0
HFD2_k127_2275026_2 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000002242 230.0
HFD2_k127_2275026_3 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.00000000000000000000000000000000137 133.0
HFD2_k127_2275026_4 response regulator, receiver - - - 0.00000000000000000003706 96.0
HFD2_k127_2275026_6 Tetratricopeptide repeat - - - 0.000000003481 67.0
HFD2_k127_2275026_7 4Fe-4S binding domain K00395,K02572,K03616 - 1.8.99.2 0.00003049 54.0
HFD2_k127_2275696_0 phospholipase Carboxylesterase - - - 0.000000000000000000000000000000001718 142.0
HFD2_k127_2275696_1 Mandelate racemase muconate lactonizing enzyme - - - 0.000000000000000000000000000000008069 138.0
HFD2_k127_2275742_0 PFAM Sodium sulphate symporter K03319,K11106 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009712 546.0
HFD2_k127_2275742_1 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 439.0
HFD2_k127_2275742_2 Uncharacterized conserved protein (DUF2267) - - - 0.0000000000000000000000000000000000000000000002872 171.0
HFD2_k127_2275742_3 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.000000000000000000000000000000008063 128.0
HFD2_k127_2275742_4 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.0000000000000000000000000001193 123.0
HFD2_k127_2275742_5 Protein of unknown function (DUF1488) - - - 0.000001856 54.0
HFD2_k127_228277_0 ABC transporter K02049 - - 0.00000000000000000000000000000000000000000000000000000000007394 211.0
HFD2_k127_228277_1 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000002634 202.0
HFD2_k127_228277_2 Menaquinone biosynthesis - - - 0.00000000000000002126 94.0
HFD2_k127_2333963_0 membrane carboxypeptidase (Penicillin-binding protein) - - - 6.314e-219 713.0
HFD2_k127_2333963_1 Amidohydrolase K07045 - - 0.000000000000000000000000000001588 134.0
HFD2_k127_2333963_2 coenzyme F420-1:gamma-L-glutamate ligase activity K04719 - 1.13.11.79 0.000000000000000000000000007598 119.0
HFD2_k127_2333963_3 NMT1-like family K02051 - - 0.000000000004067 77.0
HFD2_k127_2333963_4 NMT1-like family - - - 0.00000000003846 74.0
HFD2_k127_2343731_0 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007413 509.0
HFD2_k127_2343731_1 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 336.0
HFD2_k127_235365_0 ABC transporter K06020 - 3.6.3.25 4.607e-289 894.0
HFD2_k127_235365_1 Phosphate transporter family K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 398.0
HFD2_k127_235365_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009651 331.0
HFD2_k127_235365_3 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004275 271.0
HFD2_k127_235365_4 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000001564 151.0
HFD2_k127_235365_5 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00042 - 1.1.1.60 0.0000000000000000000000000000000000007695 151.0
HFD2_k127_235365_6 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase K07559 - - 0.0000000000000000000000000000000002789 138.0
HFD2_k127_235365_7 NMT1-like family K02051 - - 0.00000000000000001887 94.0
HFD2_k127_235365_8 AntiSigma factor K07167 - - 0.0000004108 57.0
HFD2_k127_2355952_0 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005088 391.0
HFD2_k127_2355952_1 PFAM ABC transporter K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006657 290.0
HFD2_k127_2355952_2 Formyl transferase K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000002366 261.0
HFD2_k127_2355952_3 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000007568 213.0
HFD2_k127_2355952_4 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000013 142.0
HFD2_k127_2355952_5 NMT1/THI5 like K02051 - - 0.00000000000000000000000000000000002616 147.0
HFD2_k127_2355952_6 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms K07027 - - 0.00000000000000000000000000005503 130.0
HFD2_k127_2355952_7 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.0000000004979 63.0
HFD2_k127_2362529_0 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000003219 206.0
HFD2_k127_2362529_1 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000000000003194 130.0
HFD2_k127_2362529_2 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000000000002338 126.0
HFD2_k127_2362529_3 CoA-transferase family III - - - 0.00003926 48.0
HFD2_k127_2362529_4 NMT1-like family K02051 - - 0.0003556 52.0
HFD2_k127_2368606_0 Gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001907 284.0
HFD2_k127_23824_0 GAD domain K01876 - 6.1.1.12 2.295e-229 732.0
HFD2_k127_23824_1 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004741 552.0
HFD2_k127_23824_2 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 475.0
HFD2_k127_23824_3 - - - - 0.0000000000000000000000000000000009385 139.0
HFD2_k127_23824_4 - - - - 0.000000000000000000000000000001513 131.0
HFD2_k127_23824_5 - - - - 0.00000000000000001865 91.0
HFD2_k127_2389025_0 Metallopeptidase family M24 K01262,K01271 - 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004885 391.0
HFD2_k127_2389025_1 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000493 343.0
HFD2_k127_2389025_2 Belongs to the multicopper oxidase YfiH RL5 family K05810 GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0030312,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0046983,GO:0055114,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000009557 225.0
HFD2_k127_2389025_3 Sigma-54 interaction domain K07714,K07715 - - 0.00000000000000000000000002977 110.0
HFD2_k127_2389025_4 deoxyhypusine monooxygenase activity K05384,K05386 - - 0.000000004568 66.0
HFD2_k127_2394976_0 PFAM Response regulator receiver domain - - - 0.0000000000000000000000000007611 119.0
HFD2_k127_2394976_1 DNA-dependent DNA replication K02315 - - 0.0000000001942 63.0
HFD2_k127_2394976_2 sequence-specific DNA binding - - - 0.00004346 49.0
HFD2_k127_2398380_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 3.265e-222 692.0
HFD2_k127_2398380_1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 318.0
HFD2_k127_2398380_2 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006503 263.0
HFD2_k127_2398380_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000001058 214.0
HFD2_k127_2398380_4 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000002885 125.0
HFD2_k127_2398380_5 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000001682 77.0
HFD2_k127_2398380_7 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0000000001683 65.0
HFD2_k127_2410874_0 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999,K11959 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 449.0
HFD2_k127_2410874_1 COG0784 FOG CheY-like receiver K03413 - - 0.00000000000001792 81.0
HFD2_k127_2410874_2 - - - - 0.000000002268 61.0
HFD2_k127_242340_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003835 377.0
HFD2_k127_242340_1 PFAM Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 362.0
HFD2_k127_242340_2 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000009641 255.0
HFD2_k127_242340_3 Methyltransferase domain - - - 0.000000000000000000000000000000000000002187 155.0
HFD2_k127_242340_4 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000005213 154.0
HFD2_k127_242340_5 Glycosyl transferase family group 2 - - - 0.00000000000000000000000001144 121.0
HFD2_k127_242340_7 PFAM Glycosyl transferase family 2 - - - 0.000000000000002692 77.0
HFD2_k127_242340_8 - - - - 0.0007966 51.0
HFD2_k127_2443815_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 443.0
HFD2_k127_2443815_1 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000005888 147.0
HFD2_k127_2443815_2 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000002294 125.0
HFD2_k127_2527251_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 529.0
HFD2_k127_2527251_1 Methionine synthase K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007286 333.0
HFD2_k127_2527251_2 Phosphoribosyl transferase domain K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000002104 213.0
HFD2_k127_2527251_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000005616 173.0
HFD2_k127_2527251_4 Peptidase, M23 - - - 0.000000000000000000000000000000000002865 143.0
HFD2_k127_2530874_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004395 351.0
HFD2_k127_2530874_1 NMT1-like family - - - 0.0000000000000000000000000000000000000000000000002691 191.0
HFD2_k127_2546633_0 transposition - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 451.0
HFD2_k127_2546633_1 PFAM transposase IS3 IS911 family protein - - - 0.0000000000000000000000000000000000000000000002367 169.0
HFD2_k127_2546633_2 PFAM oxidoreductase domain protein - - - 0.0000000000000585 72.0
HFD2_k127_2546633_3 - - - - 0.000000000000101 78.0
HFD2_k127_2558636_0 FAD linked oxidase - - - 1.013e-244 763.0
HFD2_k127_2558636_1 Bacterial regulatory protein, Fis family K07715 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 447.0
HFD2_k127_2558636_10 TIGRFAM MazG family protein K02428,K02499 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000006177 254.0
HFD2_k127_2558636_11 dienelactone hydrolase K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000105 197.0
HFD2_k127_2558636_12 nuclear chromosome segregation - - - 0.000000000001497 75.0
HFD2_k127_2558636_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07711 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000067 439.0
HFD2_k127_2558636_3 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007624 386.0
HFD2_k127_2558636_4 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000826 383.0
HFD2_k127_2558636_5 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006254 324.0
HFD2_k127_2558636_6 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005614 299.0
HFD2_k127_2558636_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357 299.0
HFD2_k127_2558636_8 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00018 - 1.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003508 287.0
HFD2_k127_2558636_9 ATPase associated with various cellular activities, AAA_5 K02584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005527 260.0
HFD2_k127_2585159_0 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000004237 153.0
HFD2_k127_2585159_1 - - - - 0.0000000000000000000002036 96.0
HFD2_k127_2623198_0 SpoVR family K06415 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 617.0
HFD2_k127_2623198_1 Belongs to the UPF0229 family K09786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 511.0
HFD2_k127_2623198_2 PFAM PrkA AAA K07180 - - 0.0000000000000000000000000000000000000002443 150.0
HFD2_k127_2623198_3 Shikimate dehydrogenase substrate binding domain K00014 - 1.1.1.25 0.000009638 51.0
HFD2_k127_2633684_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01006 - 2.7.9.1 0.0 1197.0
HFD2_k127_2633684_1 Heat shock 70 kDa protein K04043 - - 1.12e-303 941.0
HFD2_k127_2633684_10 Prokaryotic N-terminal methylation motif - - - 0.0000000000001163 77.0
HFD2_k127_2633684_2 TIGRFAM type IV-A pilus assembly ATPase PilB K02652 - - 4.602e-208 661.0
HFD2_k127_2633684_3 DnaJ central domain K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002944 492.0
HFD2_k127_2633684_4 Type II secretion system (T2SS), protein F K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004689 464.0
HFD2_k127_2633684_5 Two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 341.0
HFD2_k127_2633684_6 PFAM glycosyl transferase family 39 K14340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003688 268.0
HFD2_k127_2633684_7 GrpE K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000003018 165.0
HFD2_k127_2633684_8 Bacterial membrane protein, YfhO - - - 0.000000000000000000000000000000000000000001765 179.0
HFD2_k127_2633684_9 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000001373 142.0
HFD2_k127_264405_0 PFAM Dihydrodipicolinate synthetase K11946,K11949,K14585 - 4.1.2.34,4.1.2.45 0.00000000000000000000000000000000000000000000000000000000000000000000000007286 260.0
HFD2_k127_264405_1 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000000000000000002811 221.0
HFD2_k127_264405_2 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000009569 193.0
HFD2_k127_264405_3 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000606 192.0
HFD2_k127_264405_4 FAD binding domain K13796 - - 0.000000000000000000000000000000000000000003758 160.0
HFD2_k127_264405_5 NMT1-like family K02051 - - 0.0000001083 64.0
HFD2_k127_2647684_0 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007881 268.0
HFD2_k127_2647684_1 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000003099 236.0
HFD2_k127_2647684_2 Tripartite tricarboxylate transporter family receptor - - - 0.00000000006606 64.0
HFD2_k127_2650713_0 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 2.803e-214 686.0
HFD2_k127_2650713_1 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 616.0
HFD2_k127_2650713_2 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate K01612 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044464 4.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 552.0
HFD2_k127_2651073_0 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 335.0
HFD2_k127_2651073_1 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000002568 201.0
HFD2_k127_2651073_2 NMT1-like family - - - 0.00000000000000000000000000000000000003212 156.0
HFD2_k127_2651073_3 WYL domain K13572 - - 0.00000000000000000000000000000009912 128.0
HFD2_k127_2651073_4 NMT1/THI5 like K02051 - - 0.00000001153 59.0
HFD2_k127_2651073_5 WYL domain K13572 - - 0.0001857 44.0
HFD2_k127_2653636_0 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.00000000000000000000000000000000000000000000001505 182.0
HFD2_k127_2653636_1 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000001156 115.0
HFD2_k127_2654337_0 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000000000000000000000000000000000002454 198.0
HFD2_k127_2654337_1 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000415 201.0
HFD2_k127_2654337_3 Di-iron-containing protein involved in the repair of iron-sulfur clusters - - - 0.000000000000000000000000003386 117.0
HFD2_k127_2654337_6 Asp/Glu/Hydantoin racemase K01799 - 5.2.1.1 0.0000000000000000000003536 105.0
HFD2_k127_2654337_8 ABC transporter substrate binding protein K01989 - - 0.000000000000004266 77.0
HFD2_k127_2654337_9 Substrate binding domain of ABC-type glycine betaine transport system K15551 - - 0.000000254 63.0
HFD2_k127_2656809_0 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 507.0
HFD2_k127_2656809_1 Belongs to the LarC family K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006116 345.0
HFD2_k127_2656809_2 Alpha/beta hydrolase of unknown function (DUF1100) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 328.0
HFD2_k127_2656809_3 cyclopropane-fatty-acyl-phospholipid synthase K16868 - 2.1.1.265 0.00000000000000000000000000000000000000000000000000000000006818 210.0
HFD2_k127_2656809_4 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.000000000000000000000000000000000000000000000000001171 192.0
HFD2_k127_2656999_0 Chemotaxis protein histidine kinase and related kinases K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 321.0
HFD2_k127_2656999_1 CHASE3 domain K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003884 308.0
HFD2_k127_2656999_2 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000000000000000000000008401 177.0
HFD2_k127_2670022_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 8.309e-282 875.0
HFD2_k127_2670022_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 426.0
HFD2_k127_2670022_10 Polysulphide reductase K00185 - - 0.00000000004782 63.0
HFD2_k127_2670022_2 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004061 412.0
HFD2_k127_2670022_3 protein involved in outer membrane biogenesis K07290 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003626 406.0
HFD2_k127_2670022_4 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 306.0
HFD2_k127_2670022_5 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000002673 268.0
HFD2_k127_2670022_6 Protein of unknown function (DUF3341) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001535 263.0
HFD2_k127_2670022_7 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004107 250.0
HFD2_k127_2670022_8 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.00000000000000000001018 96.0
HFD2_k127_2670022_9 - - - - 0.0000000000000004167 84.0
HFD2_k127_2672988_0 COGs COG3328 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007066 430.0
HFD2_k127_2672988_1 - - - - 0.0000000000000000000000000000000000000000004296 165.0
HFD2_k127_2672988_2 Formyl transferase - - - 0.0000000000000000000000000006125 118.0
HFD2_k127_2672988_3 COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K04108 - 1.3.7.9 0.0000000000000000001237 91.0
HFD2_k127_2672988_4 Family of unknown function (DUF5329) - - - 0.00000302 52.0
HFD2_k127_2672988_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0002962 43.0
HFD2_k127_2679449_0 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.0000000000000000000000000000000000000000000000000005321 201.0
HFD2_k127_2679449_1 Methyltransferase domain - - - 0.000000000000000000000000000001852 134.0
HFD2_k127_2679449_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.000000000000000000000000000003923 121.0
HFD2_k127_2679449_3 NMT1-like family - - - 0.000000000000000000000000001274 124.0
HFD2_k127_2679449_4 NMT1-like family K02051 - - 0.000000000001072 79.0
HFD2_k127_2679449_5 Molybdopterin-binding domain of aldehyde dehydrogenase - - - 0.000000000001843 68.0
HFD2_k127_268123_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000945 411.0
HFD2_k127_268123_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000001765 212.0
HFD2_k127_268123_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K05580 - 1.6.5.3 0.000000000000000000000000000000000000000000000005879 177.0
HFD2_k127_268123_3 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000000000000002143 153.0
HFD2_k127_268123_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000000003258 127.0
HFD2_k127_2682482_0 Belongs to the TPP enzyme family K01576 - 4.1.1.7 1.315e-225 713.0
HFD2_k127_2682482_1 AMP binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 397.0
HFD2_k127_2682482_2 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 340.0
HFD2_k127_2682482_3 III protein, CoA-transferase family K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006299 308.0
HFD2_k127_2682482_4 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000004562 178.0
HFD2_k127_2682482_5 Belongs to the P(II) protein family K04752 - - 0.0000000000000000000000001097 109.0
HFD2_k127_2684826_0 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 523.0
HFD2_k127_2684826_1 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.00000002423 58.0
HFD2_k127_2691229_0 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 467.0
HFD2_k127_2691229_1 PFAM Rhodanese domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 385.0
HFD2_k127_2691229_2 TIM-barrel fold metal-dependent hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001796 263.0
HFD2_k127_2691229_3 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000002771 175.0
HFD2_k127_2691229_4 - - - - 0.00000000000000000000000000000000000001778 150.0
HFD2_k127_2691229_5 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.0000000000000000000001274 109.0
HFD2_k127_2691229_6 Amidohydrolase K03392 - 4.1.1.45 0.00000000000000000003294 93.0
HFD2_k127_2691229_7 Universal stress protein family - - - 0.0000000000000000003581 93.0
HFD2_k127_2703871_0 Belongs to the UbiD family K03182 - 4.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005107 465.0
HFD2_k127_2703871_1 DMSO reductase, iron-sulfur subunit K07307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001325 273.0
HFD2_k127_2703871_2 Molydopterin dinucleotide binding domain K10700,K17050 - 1.17.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000007951 270.0
HFD2_k127_2703871_3 YHS domain - - - 0.000001984 53.0
HFD2_k127_2704645_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 537.0
HFD2_k127_2704645_1 - - - - 0.000000000000007921 74.0
HFD2_k127_2709080_0 Thiamine pyrophosphate enzyme, central domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 351.0
HFD2_k127_2709080_1 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000001932 199.0
HFD2_k127_2709080_2 xaa-pro dipeptidase K01271 K01262,K01271 - 3.4.11.9,3.4.13.9 0.000000000000000000000000000001445 136.0
HFD2_k127_2709080_3 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.0000000000000001723 84.0
HFD2_k127_2709080_4 COGs COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.00000001844 66.0
HFD2_k127_2709080_5 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00004621 50.0
HFD2_k127_2710321_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007049 490.0
HFD2_k127_2710321_1 thiamine-containing compound biosynthetic process K04102 - 4.1.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 409.0
HFD2_k127_2710321_10 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000001555 193.0
HFD2_k127_2710321_11 Catalyzes the conversion of maleate to fumarate K01799 - 5.2.1.1 0.00000000000000000000000000000000000000000002433 170.0
HFD2_k127_2710321_12 aldehyde oxidase and xanthine dehydrogenase a b hammerhead K00087 - 1.17.1.4 0.00000000000000003348 81.0
HFD2_k127_2710321_13 Acetyltransferase (GNAT) family - - - 0.0000000001903 61.0
HFD2_k127_2710321_14 GHKL domain - - - 0.0000000152 67.0
HFD2_k127_2710321_2 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM-like protein K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007291 375.0
HFD2_k127_2710321_3 CoA-transferase family III K07544 - 2.8.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003078 369.0
HFD2_k127_2710321_4 Associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007354 364.0
HFD2_k127_2710321_5 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003753 326.0
HFD2_k127_2710321_6 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000006304 233.0
HFD2_k127_2710321_7 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS-like protein K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000002821 224.0
HFD2_k127_2710321_8 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000006666 203.0
HFD2_k127_2710321_9 cytochrome c - - - 0.00000000000000000000000000000000000000000000000002846 191.0
HFD2_k127_2711707_0 NAD(P)-binding Rossmann-like domain - - - 3.622e-200 640.0
HFD2_k127_2711707_1 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 435.0
HFD2_k127_2711707_10 NMT1-like family K02051 - - 0.0000000000000007375 89.0
HFD2_k127_2711707_11 Amidohydrolase - - - 0.000000000000001298 89.0
HFD2_k127_2711707_12 Glyoxalase-like domain K08234 - - 0.00008979 50.0
HFD2_k127_2711707_2 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003587 357.0
HFD2_k127_2711707_3 ABC transporter, phosphonate, periplasmic substrate-binding protein K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005121 338.0
HFD2_k127_2711707_4 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 322.0
HFD2_k127_2711707_5 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001529 284.0
HFD2_k127_2711707_6 Pfam:AmoA K07120 - - 0.0000000000000000000000000000000000000000000000000000000000000001454 233.0
HFD2_k127_2711707_7 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000001911 229.0
HFD2_k127_2711707_8 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000005264 188.0
HFD2_k127_2711707_9 TRAP transporter solute receptor TAXI family protein K07080 - - 0.00000000000000000000000000000000000000000000126 179.0
HFD2_k127_271269_0 AMP-binding enzyme K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000004354 193.0
HFD2_k127_271269_1 proline dipeptidase activity K08688 - 3.5.3.3 0.0000000000000000000000000000000000000000000000000002259 196.0
HFD2_k127_271269_2 Creatinase/Prolidase N-terminal domain - - - 0.0000000000002832 81.0
HFD2_k127_2722705_0 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 304.0
HFD2_k127_2722705_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.0000000000000000000000000000000000000000000003329 185.0
HFD2_k127_2722705_2 Class II aldolase K01628 - 4.1.2.17 0.00000000000000004722 93.0
HFD2_k127_2722705_3 Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis K00757 - 2.4.2.3 0.000000000000002581 81.0
HFD2_k127_2729570_0 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs K07303 - 1.3.99.16 4.423e-212 682.0
HFD2_k127_2729570_1 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.000000000000000000148 98.0
HFD2_k127_272963_0 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000000006867 194.0
HFD2_k127_272963_1 von Willebrand factor, type A - - - 0.0000000000000000000000001547 123.0
HFD2_k127_272963_2 CARDB - - - 0.0000001716 61.0
HFD2_k127_2735515_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 6.883e-223 696.0
HFD2_k127_2735515_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 333.0
HFD2_k127_2735515_2 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002782 311.0
HFD2_k127_2735515_3 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006465 262.0
HFD2_k127_2735515_4 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000001572 265.0
HFD2_k127_2735515_5 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000004761 210.0
HFD2_k127_2735515_6 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.0000000000000000000000000000000000000000000000000008662 190.0
HFD2_k127_2735515_7 PFAM phosphatidate cytidylyltransferase K00981 - 2.7.7.41 0.000000000000000000000000000000000000000005813 167.0
HFD2_k127_2735515_8 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000002273 151.0
HFD2_k127_2736246_0 PGAP1-like protein - - - 2.299e-273 847.0
HFD2_k127_2736246_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000002587 252.0
HFD2_k127_2736246_2 glyoxalase III activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009738 239.0
HFD2_k127_2736246_3 Urate oxidase N-terminal - - - 0.000000000000000000000000000000000000000000000000000000001221 209.0
HFD2_k127_2736246_4 Polyprenyl synthetase K02523,K13787 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.0000000000000000000000000000000000000000000000000003039 198.0
HFD2_k127_2736246_5 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000005959 166.0
HFD2_k127_2736246_6 - - - - 0.00000000000003458 83.0
HFD2_k127_2736246_7 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000393 48.0
HFD2_k127_2744484_0 NMT1/THI5 like - - - 0.00000000000000000000000000000000000000000000000000000000005909 217.0
HFD2_k127_2744484_1 Class II Aldolase and Adducin N-terminal domain - - - 0.00000000000000000000000000003805 126.0
HFD2_k127_2744484_2 NMT1/THI5 like - - - 0.00000000000000002054 85.0
HFD2_k127_2744484_3 class II Aldolase K18613 GO:0003674,GO:0003824,GO:0005488,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009111,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0017144,GO:0030145,GO:0034641,GO:0042365,GO:0042737,GO:0042816,GO:0042820,GO:0043167,GO:0043169,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0047431,GO:0071704,GO:0072524,GO:0072526,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 4.1.1.51 0.0001843 46.0
HFD2_k127_2751354_0 Cysteine-rich domain - - - 0.00000000000000000000000000000000000000000000000000000000000000004806 238.0
HFD2_k127_2751354_1 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000004924 190.0
HFD2_k127_2751354_2 Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis K00757 - 2.4.2.3 0.00000000000000000000001566 105.0
HFD2_k127_2751354_3 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000007587 83.0
HFD2_k127_2755819_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1309.0
HFD2_k127_2755819_1 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000623 501.0
HFD2_k127_2755819_2 DEAD DEAH box helicase K03654 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000005533 237.0
HFD2_k127_2755819_3 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000594 233.0
HFD2_k127_2777659_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.000000000000000000000000000000000000000000000000000000000003126 213.0
HFD2_k127_2777659_1 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.0000000000000000000000000000000000000000004744 169.0
HFD2_k127_2777659_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000959 67.0
HFD2_k127_2778766_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2086.0
HFD2_k127_2778766_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1923.0
HFD2_k127_2778766_10 With S4 and S5 plays an important role in translational accuracy K02950 - - 0.00000000000000000000000000000000000000000000000000000000000002911 215.0
HFD2_k127_2778766_11 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000005453 213.0
HFD2_k127_2778766_12 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000001066 211.0
HFD2_k127_2778766_13 Forms part of the polypeptide exit tunnel K02926 - - 0.000000000000000000000000000000000000000000000000000000000007864 214.0
HFD2_k127_2778766_14 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000003412 205.0
HFD2_k127_2778766_15 Ribosomal protein L6 K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000008698 203.0
HFD2_k127_2778766_16 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000009579 179.0
HFD2_k127_2778766_17 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000002966 173.0
HFD2_k127_2778766_18 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000000008469 163.0
HFD2_k127_2778766_19 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000002022 145.0
HFD2_k127_2778766_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1080.0
HFD2_k127_2778766_20 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000005802 143.0
HFD2_k127_2778766_21 its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000001375 141.0
HFD2_k127_2778766_22 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.00000000000000000000000000000000007939 137.0
HFD2_k127_2778766_23 One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000002347 134.0
HFD2_k127_2778766_24 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000531 128.0
HFD2_k127_2778766_25 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000000001442 114.0
HFD2_k127_2778766_26 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000006413 110.0
HFD2_k127_2778766_27 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000003683 94.0
HFD2_k127_2778766_28 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.000000003064 60.0
HFD2_k127_2778766_3 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 1.036e-199 629.0
HFD2_k127_2778766_4 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 355.0
HFD2_k127_2778766_5 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008265 332.0
HFD2_k127_2778766_6 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001194 276.0
HFD2_k127_2778766_7 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003133 263.0
HFD2_k127_2778766_8 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000001139 242.0
HFD2_k127_2778766_9 Ribosomal protein S5, C-terminal domain K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000005104 229.0
HFD2_k127_2778978_0 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003683 379.0
HFD2_k127_2778978_1 Iron-containing redox enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008572 331.0
HFD2_k127_2778978_2 ribonucleoside-diphosphate reductase activity K07735 - - 0.0000000000000000000000000000000000000000000000000005531 198.0
HFD2_k127_2778978_3 Peptidase S16, lon domain protein K07157 - - 0.000000000000000000000000000000000000001056 154.0
HFD2_k127_2778978_4 Haem-degrading - - - 0.000000000000000000000000000000000000002665 151.0
HFD2_k127_2778978_5 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000002857 150.0
HFD2_k127_2778978_6 NUDIX domain - - - 0.0000000000000000000000004819 111.0
HFD2_k127_2778978_7 Cupin 2, conserved barrel domain protein K11312 - - 0.00000000000000000002979 94.0
HFD2_k127_2778978_8 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 - 1.8.1.7 0.0000000000000005317 77.0
HFD2_k127_2778978_9 Putative zinc-finger - - - 0.000000000001688 79.0
HFD2_k127_2806391_0 Phospholipase D Transphosphatidylase K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 339.0
HFD2_k127_2806391_1 - - - - 0.00000000000004047 73.0
HFD2_k127_2806391_2 Phage integrase family - - - 0.00000000000008035 75.0
HFD2_k127_2806391_3 DNA/RNA hybrid annealing activity K07012,K19123 - - 0.00000004148 62.0
HFD2_k127_2818525_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 386.0
HFD2_k127_2818525_1 Carbon-nitrogen hydrolase K01916 - 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 310.0
HFD2_k127_2818525_2 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000001895 231.0
HFD2_k127_2818525_3 Nucleotidyl transferase K00966 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000004363 196.0
HFD2_k127_2818525_4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.0000000000000000000000000000000000000000000001115 172.0
HFD2_k127_2827421_0 Belongs to the UbiD family K03182 - 4.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 434.0
HFD2_k127_2827421_1 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000009429 166.0
HFD2_k127_2827421_2 MlaC protein - - - 0.000000000000000000000000000000000000005001 153.0
HFD2_k127_2827421_3 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.000000000000000000000000000005564 123.0
HFD2_k127_2827421_4 Maleate cis-trans isomerase K01799 - 5.2.1.1 0.0002146 51.0
HFD2_k127_2832277_0 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006411 346.0
HFD2_k127_2832277_1 PFAM short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000009858 228.0
HFD2_k127_2832277_2 Trypsin K04772 - - 0.0000000000002507 76.0
HFD2_k127_2832452_0 AMP-binding enzyme C-terminal domain K22133 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005778,GO:0005782,GO:0006082,GO:0006084,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016020,GO:0016021,GO:0016054,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0019637,GO:0019693,GO:0019752,GO:0031090,GO:0031224,GO:0031903,GO:0031907,GO:0031974,GO:0033609,GO:0033611,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044425,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0046483,GO:0050203,GO:0051186,GO:0055086,GO:0070013,GO:0071704,GO:0072521,GO:0097159,GO:0098588,GO:0098805,GO:1901135,GO:1901360,GO:1901363,GO:1901564,GO:1901575 6.2.1.8 0.0000000000000000000000000000000000000000000000194 186.0
HFD2_k127_2832452_1 Phosphopantetheine attachment site - - - 0.000001277 56.0
HFD2_k127_2832452_2 Membrane protein involved in D-alanine export - - - 0.00004497 55.0
HFD2_k127_2883481_0 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001414 254.0
HFD2_k127_2883481_1 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000002196 195.0
HFD2_k127_2883481_2 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000000002158 138.0
HFD2_k127_2883481_3 membrane - - - 0.000000000000001386 84.0
HFD2_k127_2889465_0 PFAM RNA-directed DNA polymerase (Reverse transcriptase) K00986,K15342 - 2.7.7.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 590.0
HFD2_k127_2889465_1 Class ii aldolase K01628,K18613 GO:0003674,GO:0003824,GO:0005488,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009111,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0017144,GO:0030145,GO:0034641,GO:0042365,GO:0042737,GO:0042816,GO:0042820,GO:0043167,GO:0043169,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0047431,GO:0071704,GO:0072524,GO:0072526,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 4.1.1.51,4.1.2.17 0.00000000000000000000000002524 117.0
HFD2_k127_2889465_2 - - - - 0.0000000001835 64.0
HFD2_k127_2899844_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 1.202e-272 847.0
HFD2_k127_2899844_1 Mur ligase, middle domain K02558 - 6.3.2.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 455.0
HFD2_k127_2899844_2 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007083 317.0
HFD2_k127_2899844_3 LD-carboxypeptidase K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000000000000001124 232.0
HFD2_k127_2899844_4 CoA binding domain K06929 - - 0.000000000000000000000000000000000000000000000000000000001286 207.0
HFD2_k127_2899844_5 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.00000000000000000000000000000000000000005467 153.0
HFD2_k127_2899844_6 Protein of unknown function (DUF507) - - - 0.000000000000000004561 87.0
HFD2_k127_2899844_7 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.00000000000000006654 81.0
HFD2_k127_2899844_8 Amidohydrolase family K01465 GO:0003674,GO:0003824,GO:0016787,GO:0016788,GO:0052689 3.5.2.3 0.000000007267 59.0
HFD2_k127_2906326_0 TIGRFAM molybdenum cofactor synthesis K03750,K07219 - 2.10.1.1 1.432e-207 663.0
HFD2_k127_2906326_1 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004534 273.0
HFD2_k127_2906326_2 photoreceptor activity K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000009188 258.0
HFD2_k127_2906326_3 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768,K03320 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000002846 231.0
HFD2_k127_2906326_4 HD domain K02660,K07315,K07814,K17763 - 3.1.3.3 0.00000000000000000000000007671 125.0
HFD2_k127_2906326_5 Excisionase - - - 0.000000146 55.0
HFD2_k127_2911078_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 377.0
HFD2_k127_292663_0 COG3547 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000003151 208.0
HFD2_k127_292663_1 PIN domain - - - 0.000000000000000000000000000000000019 139.0
HFD2_k127_292663_2 NMT1-like family - - - 0.000000000000000000000000000001553 134.0
HFD2_k127_292663_3 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000000000000000000001248 105.0
HFD2_k127_2929024_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 6.023e-267 842.0
HFD2_k127_2929024_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003092 438.0
HFD2_k127_2929024_2 TIGRFAM DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004471 303.0
HFD2_k127_2929024_3 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000008455 225.0
HFD2_k127_2933021_0 DNA photolyase activity K03716 - 4.1.99.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 312.0
HFD2_k127_2933021_1 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002296 288.0
HFD2_k127_2933021_2 Carbon monoxide dehydrogenase subunit G (CoxG) K09386 - - 0.0000000000000000000000000000000000000284 149.0
HFD2_k127_2933021_3 ParB domain protein nuclease K03497 - - 0.00000004357 63.0
HFD2_k127_294942_0 - - - - 0.00000000000000000000000000000000000005326 150.0
HFD2_k127_294942_1 Sodium/calcium exchanger protein K07301 - - 0.000000000000000000000000000000000001199 142.0
HFD2_k127_294942_2 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000004664 79.0
HFD2_k127_294942_3 e3 binding domain K00658 - 2.3.1.61 0.0000000000007358 74.0
HFD2_k127_294942_4 Protein of unknown function (DUF1232) - - - 0.00000004992 58.0
HFD2_k127_2960986_0 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 305.0
HFD2_k127_2960986_1 PBS lyase HEAT-like repeat - - - 0.00000000000000000001021 107.0
HFD2_k127_2960986_2 Transcriptional regulator, Fis family K02584 - - 0.000000000000002767 77.0
HFD2_k127_2978168_0 NMT1-like family - - - 0.0000000000000000000000000000000000000000000000009731 187.0
HFD2_k127_2978168_1 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000000000029 120.0
HFD2_k127_2978168_2 glyoxalase bleomycin resistance protein dioxygenase K01759,K08234 - 4.4.1.5 0.00000000000000000002555 95.0
HFD2_k127_2978168_3 ABC transporter substrate binding protein K01989 - - 0.000000000000002114 77.0
HFD2_k127_2978168_4 ABC transporter K02051,K15553 - - 0.000000000006722 76.0
HFD2_k127_2984096_0 Asparaginase - - - 5.961e-195 623.0
HFD2_k127_2984096_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001591 280.0
HFD2_k127_2984096_2 - - - - 0.00001639 54.0
HFD2_k127_3005664_0 beta-1,4-mannooligosaccharide phosphorylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007439 531.0
HFD2_k127_3005664_1 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000002307 198.0
HFD2_k127_3005664_2 DNA binding domain with preference for A/T rich regions - - - 0.00000000000000007578 87.0
HFD2_k127_3006971_0 protein conserved in bacteria K07793 - - 5.804e-219 689.0
HFD2_k127_3006971_1 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008588 414.0
HFD2_k127_3006971_2 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.00000000000000000000000000000000000000000000000000000000001189 224.0
HFD2_k127_3006971_3 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000004771 205.0
HFD2_k127_3006971_4 Tripartite tricarboxylate transporter TctB family - - - 0.00000000000000000000000000000000000000006054 155.0
HFD2_k127_3006971_5 hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000003586 145.0
HFD2_k127_3006971_6 translation initiation inhibitor, yjgF family - - - 0.000000000000000000000000000004136 123.0
HFD2_k127_3006971_7 Domain of unknown function (DUF1989) K09967 - - 0.00000000000000000005662 98.0
HFD2_k127_3024886_0 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006368 347.0
HFD2_k127_3024886_1 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000122 271.0
HFD2_k127_3024886_2 transferase activity, transferring glycosyl groups K07011 - - 0.00000000000000000000000000000000000000000000000003921 194.0
HFD2_k127_3024886_3 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 0.0000000000000000000000000000002749 130.0
HFD2_k127_3024886_4 PFAM LmbE family protein - - - 0.00000000000000000000002539 108.0
HFD2_k127_3024886_5 Polysaccharide deacetylase - - - 0.0000000000001879 75.0
HFD2_k127_3024886_6 ATP-grasp - - - 0.00000001765 61.0
HFD2_k127_3024886_7 Phosphopantetheine attachment site - - - 0.0000002538 57.0
HFD2_k127_3024886_8 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00007838 54.0
HFD2_k127_3048405_0 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002467 407.0
HFD2_k127_3048405_1 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000001596 140.0
HFD2_k127_3048405_2 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000001566 122.0
HFD2_k127_3050646_0 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007085 355.0
HFD2_k127_3050646_1 MmgE PrpD family protein - - - 0.00000000000000000000000000000000000000000000000000000000000009238 229.0
HFD2_k127_3050646_2 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.000000000002576 69.0
HFD2_k127_3055841_0 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 4.83e-256 816.0
HFD2_k127_3055841_1 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002271 248.0
HFD2_k127_3055841_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.0000000000000000000000000000000000001229 143.0
HFD2_k127_3063255_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 561.0
HFD2_k127_3063255_1 Ornithine cyclodeaminase K01750 - 4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 553.0
HFD2_k127_3063255_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate - - - 0.0000000000000000000000000000000000000000000000000000000000007477 214.0
HFD2_k127_3063255_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate - - - 0.000000000000000000000001323 104.0
HFD2_k127_3079567_0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009666 295.0
HFD2_k127_3079567_1 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000002817 186.0
HFD2_k127_3079567_2 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000004349 162.0
HFD2_k127_3091172_0 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006847 282.0
HFD2_k127_3091172_1 cell redox homeostasis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001723 269.0
HFD2_k127_3091172_2 - - - - 0.00000000001049 68.0
HFD2_k127_3091172_3 - - - - 0.000004038 52.0
HFD2_k127_3091516_0 aldehyde-lyase activity K01621 - 4.1.2.22,4.1.2.9 0.0 1435.0
HFD2_k127_3091516_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1020.0
HFD2_k127_3091516_2 CobW/HypB/UreG, nucleotide-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 554.0
HFD2_k127_3091516_3 Trypsin-like serine protease K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005005 310.0
HFD2_k127_3091516_4 Histidine kinase K14986 - 2.7.13.3 0.00000000000000000000000000000000000000000000003471 184.0
HFD2_k127_3091516_5 COG0058 Glucan phosphorylase - - - 0.0000000001534 61.0
HFD2_k127_3091516_6 PFAM Outer membrane efflux protein - - - 0.0004566 43.0
HFD2_k127_3097270_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 2.948e-276 861.0
HFD2_k127_3104342_0 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000003669 178.0
HFD2_k127_3104342_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.0000000000000000000000000000000000000003196 153.0
HFD2_k127_3104342_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - 0.00000000000000000000000000000000000002748 150.0
HFD2_k127_3104342_3 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K06034 GO:0003674,GO:0003824,GO:0006082,GO:0006732,GO:0006790,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019295,GO:0019296,GO:0044237,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0050545,GO:0051186,GO:0051188,GO:0071704,GO:1901576 4.1.1.79 0.000000000000000000000000000001178 128.0
HFD2_k127_3104342_4 oxidation-reduction process - - - 0.000000000000000000000000003458 115.0
HFD2_k127_3104342_5 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.00000000000000000000001632 105.0
HFD2_k127_3104342_6 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000002846 81.0
HFD2_k127_310439_0 Peroxisomal (S)-2-hydroxy-acid oxidase. Source PGD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 317.0
HFD2_k127_310439_1 Pfam:Arch_ATPase K02450 - - 0.000000000000000000000000000000000000000000000000009895 198.0
HFD2_k127_310439_2 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000000000000000000000000000000002677 194.0
HFD2_k127_310439_3 NMT1-like family K02051 - - 0.000000000000002128 89.0
HFD2_k127_310439_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000072 72.0
HFD2_k127_310439_5 Lysin motif - - - 0.000000008839 68.0
HFD2_k127_310439_6 PFAM methyltransferase - - - 0.00002792 49.0
HFD2_k127_312307_0 glycosyltransferase 36 associated K00702,K13688 - 2.4.1.20 0.0 1131.0
HFD2_k127_312307_1 positive regulation of growth - GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007 - 0.000000000000000000000000000001446 122.0
HFD2_k127_3126666_0 glycosyl transferase group 1 K13668 - 2.4.1.346 0.00000000000000000000000000000000000000000000000000000000003192 219.0
HFD2_k127_3126666_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000005901 133.0
HFD2_k127_3126666_2 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.00000000000000000000000009126 108.0
HFD2_k127_3126666_3 PFAM Glycosyl - - - 0.0006341 44.0
HFD2_k127_3129550_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 546.0
HFD2_k127_3129550_1 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000002127 220.0
HFD2_k127_3129550_2 DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000001573 200.0
HFD2_k127_3129550_3 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000009939 149.0
HFD2_k127_3129550_4 Transcriptional regulatory protein, C terminal K07658 - - 0.0000000000000000000000000003425 119.0
HFD2_k127_3129550_5 protein transport across the cell outer membrane K02246,K08084 - - 0.000000000421 66.0
HFD2_k127_3129550_6 type IV pilus modification protein PilV K02458,K02671 - - 0.0000001042 59.0
HFD2_k127_3129550_7 Type IV Pilus-assembly protein W K02672 - - 0.0002404 51.0
HFD2_k127_3136422_0 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009389 592.0
HFD2_k127_3136422_1 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K00666,K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 552.0
HFD2_k127_3136422_2 histidine ammonia-lyase K10775 - 4.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005693 404.0
HFD2_k127_3136422_3 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 376.0
HFD2_k127_3136422_4 DNA polymerase A domain K02335 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000004563 270.0
HFD2_k127_3136422_5 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000006765 207.0
HFD2_k127_3136422_6 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000000000000000000000000000000000000000000000009162 202.0
HFD2_k127_3136422_7 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000123 94.0
HFD2_k127_3151789_0 PASTA domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003378 567.0
HFD2_k127_3151789_1 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000003086 238.0
HFD2_k127_3151789_2 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000004955 111.0
HFD2_k127_3151789_3 Evidence 5 No homology to any previously reported sequences - - - 0.00000000424 64.0
HFD2_k127_3152755_0 ABC-type Fe3 transport system permease component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 376.0
HFD2_k127_3152755_1 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000004475 110.0
HFD2_k127_3152755_2 iron ion homeostasis K02012 - - 0.00000000000000004901 92.0
HFD2_k127_3163245_0 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000194 211.0
HFD2_k127_3163245_1 PFAM isochorismatase hydrolase - - - 0.00000000000000000000000000000000000000000000000000000004163 207.0
HFD2_k127_3163245_2 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.00000000000000000000002617 104.0
HFD2_k127_3163245_3 Glutaredoxin - - - 0.00000000000003974 73.0
HFD2_k127_3165861_0 Protein of unknown function, DUF255 K06888 - - 1.495e-222 711.0
HFD2_k127_3165861_1 Glycosyl transferase family 1 - - - 0.00000000000000000000000000001933 124.0
HFD2_k127_3165861_2 NMT1-like family - - - 0.00000000000000000000000001538 121.0
HFD2_k127_3165861_3 Class II Aldolase and Adducin N-terminal domain - - - 0.00000000000000000000003087 108.0
HFD2_k127_3165861_4 Cold shock K03704 - - 0.0000000009289 61.0
HFD2_k127_3165861_5 Belongs to the ParB family K03497 - - 0.0000000546 55.0
HFD2_k127_320272_0 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006143 252.0
HFD2_k127_320272_1 Domain of unknown function (DUF309) K09763 - - 0.0000000000000000008093 90.0
HFD2_k127_320272_2 COG4235 Cytochrome c biogenesis factor K02200 - - 0.000001974 59.0
HFD2_k127_3225626_0 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.00001778 53.0
HFD2_k127_3225626_1 to Saccharomyces cerevisiae STI1 (YOR027W) K09553 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0004857,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006457,GO:0006605,GO:0006626,GO:0006810,GO:0006839,GO:0006886,GO:0006996,GO:0007005,GO:0008104,GO:0008150,GO:0009987,GO:0015031,GO:0015833,GO:0016043,GO:0030234,GO:0030544,GO:0031072,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042030,GO:0042886,GO:0043086,GO:0044092,GO:0044424,GO:0044464,GO:0045184,GO:0046907,GO:0050790,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0051879,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0070585,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0072594,GO:0072655,GO:0097159,GO:0098772,GO:1901363 - 0.000488 48.0
HFD2_k127_323410_0 nitrite transmembrane transporter activity K02575,K08223 - - 0.000000000000000000000000000000001633 144.0
HFD2_k127_323410_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000008853 121.0
HFD2_k127_323410_2 DUF167 K09131 - - 0.0000008974 54.0
HFD2_k127_3238010_0 KR domain K03366 - 1.1.1.304,1.1.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000001444 259.0
HFD2_k127_3238010_1 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000001231 228.0
HFD2_k127_3238010_2 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000001449 151.0
HFD2_k127_3238010_3 thiamine-containing compound biosynthetic process K02051 - - 0.00000005524 64.0
HFD2_k127_3238010_4 Lactoylglutathione lyase K01759 - 4.4.1.5 0.000001104 50.0
HFD2_k127_32626_0 PFAM NMT1 THI5 like domain protein K02051 - - 0.00000000001999 76.0
HFD2_k127_32626_1 - - - - 0.0005064 46.0
HFD2_k127_3264905_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1058.0
HFD2_k127_3285258_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 9.262e-263 822.0
HFD2_k127_3285258_1 ABC-type nitrate sulfonate bicarbonate transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001752 259.0
HFD2_k127_3285258_2 Bacterial trigger factor protein (TF) C-terminus K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000008838 256.0
HFD2_k127_3285258_3 Protein of unknown function (DUF971) K03593 - - 0.0000000000000000000000001487 109.0
HFD2_k127_3285258_5 RHS Repeat - - - 0.00003421 49.0
HFD2_k127_3286106_0 Oxidoreductase K10219 - 1.1.1.312 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005215 418.0
HFD2_k127_3286106_1 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000003018 200.0
HFD2_k127_3286106_2 - - - - 0.0000000000000000876 83.0
HFD2_k127_3286106_3 Tripartite tricarboxylate transporter TctA family K07793 - - 0.000000000006911 67.0
HFD2_k127_3286106_4 Tripartite tricarboxylate transporter TctB family K07794 - - 0.00000000007689 69.0
HFD2_k127_32981_0 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 461.0
HFD2_k127_32981_1 PFAM NAD dependent epimerase dehydratase family K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009368 313.0
HFD2_k127_32981_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 302.0
HFD2_k127_32981_3 geranylgeranyl reductase activity K21401 - 1.3.99.38 0.0000000000000000000000000000000000000000324 171.0
HFD2_k127_32981_4 Methyltransferase domain - - - 0.00000000000000000000000000000000000003413 153.0
HFD2_k127_32981_5 peroxiredoxin activity K03564 - 1.11.1.15 0.0004357 50.0
HFD2_k127_3330822_0 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate K01612,K03182,K16874 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044464 4.1.1.61,4.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 475.0
HFD2_k127_3330822_1 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000007457 194.0
HFD2_k127_3330822_2 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000997 101.0
HFD2_k127_3330822_3 - - - - 0.00000000000008479 76.0
HFD2_k127_3353412_0 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000000000000000002386 203.0
HFD2_k127_3353412_1 Amidohydrolase K03392 - 4.1.1.45 0.00000000000000000000000000000000000000000000000000002894 198.0
HFD2_k127_3353412_2 - - - - 0.000000000000000000000000000001002 124.0
HFD2_k127_3353412_3 MgtC family K07507 - - 0.00002798 48.0
HFD2_k127_3388112_0 Psort location CytoplasmicMembrane, score 10.00 K03458 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003959 347.0
HFD2_k127_3388848_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1191.0
HFD2_k127_3388848_1 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 312.0
HFD2_k127_3388848_2 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 309.0
HFD2_k127_3388848_3 Putative RNA methylase family UPF0020 K15460 - 2.1.1.223 0.00000000000000000000000000000000000000000000000000000000001198 216.0
HFD2_k127_3388848_4 intermembrane phospholipid transfer K07323 - - 0.000000000000000000000000000000000000000000000000000001055 199.0
HFD2_k127_3388848_5 PFAM Mammalian cell entry related domain protein K02067 - - 0.0000000000000000000000000000000000000000003132 165.0
HFD2_k127_3388848_6 Protein of unknown function (DUF721) - - - 0.000000000000000002416 93.0
HFD2_k127_3388848_7 PFAM FAD dependent oxidoreductase K15736 - - 0.00000001339 56.0
HFD2_k127_3388848_8 aspartic-type endopeptidase activity K06985 - - 0.00004872 46.0
HFD2_k127_3421153_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000003286 168.0
HFD2_k127_3425705_0 PFAM Amino acid-binding ACT K03567 - - 0.00000000000000000000000000000000001239 141.0
HFD2_k127_3425705_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000007508 124.0
HFD2_k127_342610_0 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 334.0
HFD2_k127_342610_1 Tripartite tricarboxylate transporter TctA family K07793 - - 0.000000000000000000000000000000000000000000000000000000000000000000004528 239.0
HFD2_k127_342610_2 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000005934 224.0
HFD2_k127_342610_3 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000008207 211.0
HFD2_k127_342610_4 [2Fe-2S] binding domain - - - 0.000000000000000000000000000000000000000000000000000001191 196.0
HFD2_k127_342610_5 Tripartite tricarboxylate transporter TctB family K07794 - - 0.00000005049 61.0
HFD2_k127_3504422_0 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 429.0
HFD2_k127_3504422_1 Belongs to the peptidase S51 family K05995 GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 3.4.13.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002377 271.0
HFD2_k127_3504422_2 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000002306 180.0
HFD2_k127_3504422_3 Methyltransferase - - - 0.0000001066 53.0
HFD2_k127_3511449_0 Molydopterin dinucleotide binding domain K10700,K17050 - 1.17.99.2 1.048e-249 796.0
HFD2_k127_353466_0 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003407 449.0
HFD2_k127_353466_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005443 393.0
HFD2_k127_353466_2 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.000000000000000000000000000000000000000000000000629 184.0
HFD2_k127_3539384_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474,K13015 - 1.1.1.136 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 499.0
HFD2_k127_3539384_1 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009571 431.0
HFD2_k127_3539384_2 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 441.0
HFD2_k127_3539384_3 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 364.0
HFD2_k127_3539384_4 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001801 263.0
HFD2_k127_3539384_5 Polysaccharide biosynthesis/export protein K01991 - - 0.000000000000000000000000000000001194 144.0
HFD2_k127_3539384_6 TIGRFAM methyltransferase FkbM family - - - 0.00000000000000000000000000007566 126.0
HFD2_k127_3539384_7 Polysaccharide biosynthesis C-terminal domain - - - 0.000000001506 70.0
HFD2_k127_3539384_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K05580 - 1.6.5.3 0.00002259 49.0
HFD2_k127_3556683_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 1.391e-250 784.0
HFD2_k127_3556683_1 spermidine synthase activity K00797 GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 430.0
HFD2_k127_3556683_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000001825 269.0
HFD2_k127_3556683_3 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.000000000000000000000000000000000000000000000000000001646 195.0
HFD2_k127_3556683_4 Protein of unknown function (DUF1318) - - - 0.000000000000000000000000000000000000000001382 162.0
HFD2_k127_3556683_5 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000002636 179.0
HFD2_k127_3556683_6 Polysaccharide deacetylase K22278 - 3.5.1.104 0.000000000005782 73.0
HFD2_k127_3556777_0 acetyl-coa acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005214 271.0
HFD2_k127_3556777_1 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000002696 215.0
HFD2_k127_3556777_2 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.00000000000000000000000000156 118.0
HFD2_k127_3556777_3 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000000008781 120.0
HFD2_k127_3556777_4 Enoyl-CoA hydratase/isomerase - - - 0.00001126 49.0
HFD2_k127_3572865_0 Amidohydrolase family K15358 - 3.5.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005834 426.0
HFD2_k127_3572865_1 ABC 3 transport family K02075,K09816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003781 274.0
HFD2_k127_3572865_2 Belongs to the bacterial solute-binding protein 9 family K02077,K09815,K09818 - - 0.00000000000000000000000000000000000000000002261 170.0
HFD2_k127_3572865_3 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.00000003088 57.0
HFD2_k127_3581617_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 5.813e-243 769.0
HFD2_k127_3581617_1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 439.0
HFD2_k127_3581617_2 amino acid ABC transporter K02029 - - 0.000000000000000000000000000000000000000000000000000001111 199.0
HFD2_k127_3581617_3 glycolate biosynthetic process K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000006114 164.0
HFD2_k127_3581617_4 flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase - - - 0.0000000000000000000000000000000000002615 145.0
HFD2_k127_3581617_5 Appr-1'-p processing enzyme - - - 0.0000000000000000000000000000009574 124.0
HFD2_k127_3581617_6 PFAM glycine reductase complex selenoprotein A K10670 - 1.21.4.2,1.21.4.3,1.21.4.4 0.0000000000000000000000000008392 115.0
HFD2_k127_3581617_7 Glycine reductase complex selenoprotein A K10670 - 1.21.4.2,1.21.4.3,1.21.4.4 0.000000000002142 68.0
HFD2_k127_3581617_8 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.00000000001555 75.0
HFD2_k127_3582273_0 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 425.0
HFD2_k127_3582273_1 Major facilitator superfamily K08194 - - 0.00000000000000002381 94.0
HFD2_k127_3584831_0 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 535.0
HFD2_k127_3584831_1 Maleate cis-trans isomerase K01799 - 5.2.1.1 0.000000000000000003572 91.0
HFD2_k127_3584831_2 ABC-type proline glycine betaine transport K05847 - - 0.00000000000000001593 83.0
HFD2_k127_359236_0 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000004773 183.0
HFD2_k127_359236_1 Protein of unknown function, DUF - - - 0.0000000000000000000000000000000000003065 142.0
HFD2_k127_359236_2 Nitrate ABC transporter substrate-binding protein K02051 - - 0.0000000008283 70.0
HFD2_k127_359236_3 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06137 GO:0005575,GO:0005576 1.3.3.11 0.0000001192 62.0
HFD2_k127_3600911_0 PFAM thiamine pyrophosphate enzyme-like TPP-binding thiamine pyrophosphate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 569.0
HFD2_k127_3600911_1 ATP phosphoribosyltransferase K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 404.0
HFD2_k127_3600911_2 MmgE/PrpD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 367.0
HFD2_k127_3600911_3 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000002771 176.0
HFD2_k127_3600911_4 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000005248 153.0
HFD2_k127_3600911_5 phosphorelay sensor kinase activity K10942 - 2.7.13.3 0.000000000000000000000000000000003884 136.0
HFD2_k127_3600911_6 NMT1-like family K02051 - - 0.00000000000000003462 93.0
HFD2_k127_3600911_7 Acetyl-CoA carboxylase, biotin carboxyl carrier protein K01571,K01960 - 4.1.1.3,6.4.1.1 0.0003881 44.0
HFD2_k127_3616209_0 negative regulation of protein lipidation K19294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008311 455.0
HFD2_k127_3616209_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000006422 186.0
HFD2_k127_3616209_2 Histone methylation protein DOT1 - - - 0.0000000000000000000000000000000000000000000005939 172.0
HFD2_k127_3627058_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 4.452e-318 993.0
HFD2_k127_3627058_1 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 549.0
HFD2_k127_3627058_2 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006107 386.0
HFD2_k127_3627058_3 peptidyl-lysine modification to peptidyl-hypusine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 347.0
HFD2_k127_3627058_4 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 306.0
HFD2_k127_3627058_5 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000002779 252.0
HFD2_k127_3627058_6 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000003534 205.0
HFD2_k127_3627058_7 Archease protein family (MTH1598/TM1083) - - - 0.000000000000000000000001531 109.0
HFD2_k127_362910_0 SMART PUA domain containing protein K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007464 355.0
HFD2_k127_362910_1 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005805 325.0
HFD2_k127_362910_2 RadC-like JAB domain K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007581 282.0
HFD2_k127_362910_3 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000006569 156.0
HFD2_k127_3636270_0 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 474.0
HFD2_k127_3636270_1 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000000006955 238.0
HFD2_k127_3636270_2 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000007076 168.0
HFD2_k127_3636270_3 ABC-type transport auxiliary lipoprotein component K18480 - - 0.0000000000000000000000000000000000000000002188 166.0
HFD2_k127_3638070_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.0 1024.0
HFD2_k127_3638070_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 7.058e-289 908.0
HFD2_k127_3638070_2 Fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 390.0
HFD2_k127_3638070_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 292.0
HFD2_k127_3638070_4 Cyclic nucleotide-monophosphate binding domain K10914 - - 0.00000000000000000000000000000000000000000000000000000000002192 213.0
HFD2_k127_3638070_5 Hsp20/alpha crystallin family - - - 0.00000000000000000000000001547 114.0
HFD2_k127_3644290_0 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate K01612 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044464 4.1.1.61 0.00000000000000000000000000000000000000000000000000000000002619 219.0
HFD2_k127_3644290_1 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000009741 99.0
HFD2_k127_3645245_0 Belongs to the thiolase family K00626,K02615 - 2.3.1.174,2.3.1.223,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002847 444.0
HFD2_k127_3645245_1 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008095 313.0
HFD2_k127_3645245_2 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009265 291.0
HFD2_k127_3645245_3 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000222 282.0
HFD2_k127_3645245_4 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000002055 217.0
HFD2_k127_3646359_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 6.166e-299 938.0
HFD2_k127_3646359_1 Methionine synthase K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006046 333.0
HFD2_k127_3646359_2 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 299.0
HFD2_k127_3646359_3 auxin efflux carrier K07088 - - 0.0000000000000000000000000000000000005541 156.0
HFD2_k127_3646359_4 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008818,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.8.26 0.000001919 58.0
HFD2_k127_3667214_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K00087 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 334.0
HFD2_k127_3668834_0 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 1.155e-207 654.0
HFD2_k127_3668834_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000004772 198.0
HFD2_k127_3668834_2 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000000000000000000000000008668 166.0
HFD2_k127_3678520_0 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 359.0
HFD2_k127_3678520_1 iron ion homeostasis K02012 - - 0.0000000000000000000000000000000000000000000241 172.0
HFD2_k127_3693191_0 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 567.0
HFD2_k127_3693191_1 Cytochrome c - - - 0.000006704 49.0
HFD2_k127_3694138_0 Evidence 4 Homologs of previously reported genes of K07145,K21481 - 1.14.99.48,1.14.99.57 0.00000000000000000000000000000001721 129.0
HFD2_k127_3694138_1 Exodeoxyribonuclease III K01142 - 3.1.11.2 0.00000000000000000000000000006933 116.0
HFD2_k127_3694138_2 NMT1-like family K02051 - - 0.0000000000000000001192 101.0
HFD2_k127_3694138_3 COG0747 ABC-type dipeptide transport system, periplasmic component K02035 - - 0.0000008977 53.0
HFD2_k127_3694138_4 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000002287 57.0
HFD2_k127_3699000_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 4.825e-233 746.0
HFD2_k127_3699000_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 337.0
HFD2_k127_3699000_2 PFAM peptidase - - - 0.00000000000000000000000000000000000000000000000000004824 208.0
HFD2_k127_3699000_3 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000001568 165.0
HFD2_k127_3699000_4 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000164 162.0
HFD2_k127_3699000_5 Creatinase/Prolidase N-terminal domain K01271 - 3.4.13.9 0.000000000000000003193 97.0
HFD2_k127_3699000_6 Putative regulatory protein - - - 0.000000002917 60.0
HFD2_k127_3724863_0 Leucyl-tRNA synthetase, Domain 2 K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1129.0
HFD2_k127_3724863_1 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 1.211e-217 686.0
HFD2_k127_3724863_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 470.0
HFD2_k127_3724863_3 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000000000000000004289 203.0
HFD2_k127_3724863_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000001271 139.0
HFD2_k127_3724863_5 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000002621 137.0
HFD2_k127_3724863_6 Lipopolysaccharide-assembly - - - 0.0000000000000001367 87.0
HFD2_k127_3724863_7 Binds directly to 16S ribosomal RNA K02968 - - 0.000001851 55.0
HFD2_k127_3728037_0 Lysin motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000001583 245.0
HFD2_k127_3729662_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 2.362e-280 882.0
HFD2_k127_3729662_1 HlyD family secretion protein K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007414 291.0
HFD2_k127_3730259_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 478.0
HFD2_k127_3730259_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009108 432.0
HFD2_k127_3730259_2 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K00666,K01897,K12507 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 302.0
HFD2_k127_3730259_3 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000004899 198.0
HFD2_k127_3730259_4 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000004213 158.0
HFD2_k127_3730259_5 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000000000001114 132.0
HFD2_k127_3730259_6 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.000000000000003894 86.0
HFD2_k127_3730259_7 Phenylphosphate carboxylase gamma subunit (Phenyl_P_gamma) - - - 0.00000003641 59.0
HFD2_k127_3730259_8 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.00005288 55.0
HFD2_k127_3730259_9 Transcriptional regulator - - - 0.0000621 48.0
HFD2_k127_3751997_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005462 430.0
HFD2_k127_3751997_1 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000372 412.0
HFD2_k127_3751997_10 Could be involved in septation K06412 - - 0.00000000000000000000000000000000004412 138.0
HFD2_k127_3751997_11 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000000001716 132.0
HFD2_k127_3751997_12 Predicted membrane protein (DUF2232) - - - 0.00000000000000000000000007628 119.0
HFD2_k127_3751997_13 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000003755 104.0
HFD2_k127_3751997_14 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000002239 97.0
HFD2_k127_3751997_15 Methyltransferase - - - 0.0000000000000001024 80.0
HFD2_k127_3751997_16 Belongs to the 'phage' integrase family K14059 - - 0.0000000005323 64.0
HFD2_k127_3751997_2 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 378.0
HFD2_k127_3751997_3 Inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006981 278.0
HFD2_k127_3751997_4 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000008473 226.0
HFD2_k127_3751997_5 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000001133 209.0
HFD2_k127_3751997_6 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000004843 189.0
HFD2_k127_3751997_7 spore germination - - - 0.000000000000000000000000000000000000000001973 168.0
HFD2_k127_3751997_8 Ribosomal protein L9, N-terminal domain K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000002321 148.0
HFD2_k127_3751997_9 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000003328 148.0
HFD2_k127_3755800_0 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006165 313.0
HFD2_k127_3755800_2 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.000000000000000001038 98.0
HFD2_k127_3774377_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005267 293.0
HFD2_k127_3774377_1 - - - - 0.0000000000000002178 93.0
HFD2_k127_3782348_0 Aminoacyl-tRNA editing domain K01881 - 6.1.1.15 1.382e-230 726.0
HFD2_k127_3782348_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009055,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0022900,GO:0030312,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046429,GO:0046490,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0052592,GO:0055114,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 534.0
HFD2_k127_3782348_2 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009147 348.0
HFD2_k127_3782348_3 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 336.0
HFD2_k127_3782348_4 R3H domain protein K06346 - - 0.00000000000000000000000000000000000004457 154.0
HFD2_k127_3782348_5 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000002101 93.0
HFD2_k127_3782348_6 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000000000000007224 93.0
HFD2_k127_3782348_7 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000000005225 76.0
HFD2_k127_3787352_0 radical SAM K06871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003842 499.0
HFD2_k127_3787352_1 Periplasmic component of the Tol biopolymer transport system K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007701 409.0
HFD2_k127_3787352_2 Metallopeptidase family M24 - - - 0.00000000000000000000000000000000000000000000000000000005291 209.0
HFD2_k127_3787641_0 FAD binding domain K05898,K13796 - 1.3.99.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 459.0
HFD2_k127_3787641_1 Conserved carboxylase domain K01571 - 4.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 407.0
HFD2_k127_3787641_2 NMT1-like family - - - 0.0000000000000000000000000000000000000000000000003597 188.0
HFD2_k127_3787641_3 pyridoxamine-phosphate oxidase activity K00275 - 1.4.3.5 0.00000006724 56.0
HFD2_k127_3787641_5 Bacterial extracellular solute-binding protein - - - 0.0006171 45.0
HFD2_k127_3789759_0 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008982 465.0
HFD2_k127_3789759_1 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000001549 166.0
HFD2_k127_3813356_0 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000391 195.0
HFD2_k127_3813356_1 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.00000000000000000000000000000000000000000002757 174.0
HFD2_k127_3814935_0 PEP-utilising enzyme, N-terminal K08484 - 2.7.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007747 424.0
HFD2_k127_3819775_0 A G-specific K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000006689 239.0
HFD2_k127_3819775_1 EamA-like transporter family - - - 0.0000000009962 69.0
HFD2_k127_3820226_0 Glutamate synthase K00266 - 1.4.1.13,1.4.1.14 1.733e-205 645.0
HFD2_k127_3825856_0 D-isomer specific 2-hydroxyacid dehydrogenase K00018 - 1.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000008168 268.0
HFD2_k127_3825856_1 alpha/beta hydrolase fold - - - 0.00000000000000000000001998 102.0
HFD2_k127_3825856_2 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.0000000000000261 74.0
HFD2_k127_3825856_3 reductase - - - 0.00000000003148 69.0
HFD2_k127_3834198_0 Xanthine dehydrogenase K03520 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 528.0
HFD2_k127_3834198_1 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate K01612 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044464 4.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 484.0
HFD2_k127_3834198_2 Protein of unknown function (DUF1847) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 298.0
HFD2_k127_3834198_3 Amidohydrolase K03392 - 4.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 300.0
HFD2_k127_3834198_4 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000003169 211.0
HFD2_k127_3834198_5 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000006611 182.0
HFD2_k127_3834198_6 conserved protein, contains double-stranded beta-helix domain - - - 0.000000000000006472 81.0
HFD2_k127_383614_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000004858 148.0
HFD2_k127_383614_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07323 - - 0.000000000000000000000000000000001052 137.0
HFD2_k127_383614_2 Glycosyltransferase Family 4 - - - 0.00000000002602 65.0
HFD2_k127_3844950_0 Belongs to the UbiD family K03182 - 4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 359.0
HFD2_k127_3844950_1 NADH flavin oxidoreductase NADH oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007029 319.0
HFD2_k127_384544_0 Pyruvate ferredoxin oxidoreductase and related K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 477.0
HFD2_k127_384544_1 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004364 321.0
HFD2_k127_384544_2 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000001494 271.0
HFD2_k127_384544_3 PFAM thiamine pyrophosphate protein domain protein TPP-binding K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000005123 261.0
HFD2_k127_384544_4 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000005394 243.0
HFD2_k127_384544_5 Radical SAM superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000004283 234.0
HFD2_k127_384544_6 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000002337 111.0
HFD2_k127_3864782_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 570.0
HFD2_k127_3864782_1 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000001935 172.0
HFD2_k127_3864782_2 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000003525 102.0
HFD2_k127_3864782_3 Fic/DOC family - - - 0.00004446 49.0
HFD2_k127_3876093_0 xanthine dehydrogenase activity K00087,K12528 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 364.0
HFD2_k127_3876093_1 Cell shape determining protein MreB Mrl K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001518 280.0
HFD2_k127_3876093_10 peroxiredoxin activity K03564 - 1.11.1.15 0.0003381 48.0
HFD2_k127_3876093_2 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002476 272.0
HFD2_k127_3876093_3 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000004223 180.0
HFD2_k127_3876093_4 MFS_1 like family - - - 0.00000000000000000000000000000000000000000001772 177.0
HFD2_k127_3876093_5 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - 0.00000000000000000000000000000000000000000005776 167.0
HFD2_k127_3876093_6 Dopa 4,5-dioxygenase family K10253 - - 0.000000000000000000000000000000000000000006767 159.0
HFD2_k127_3876093_7 sulfopyruvate decarboxylase, alpha subunit K06034 - 4.1.1.79 0.0000000000000000000000000002605 120.0
HFD2_k127_3876093_8 Putative prokaryotic signal transducing protein - - - 0.0000000000000000000000000006929 116.0
HFD2_k127_3876093_9 alpha/beta hydrolase fold - - - 0.00000000000000314 86.0
HFD2_k127_3877101_0 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000003321 248.0
HFD2_k127_3877101_1 Met-10+ like-protein - - - 0.000000000000000000000000000000000000000000000006292 181.0
HFD2_k127_3877101_2 amino acid K03294,K13868 - - 0.00000000000000000000000000001048 121.0
HFD2_k127_3877101_3 Outer membrane lipoprotein-sorting protein - - - 0.00000000000000000000001266 112.0
HFD2_k127_3877101_4 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.00000000000000000002893 106.0
HFD2_k127_3883209_0 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 351.0
HFD2_k127_3883209_1 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000001755 216.0
HFD2_k127_3883209_2 Lumazine binding domain K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000005976 205.0
HFD2_k127_3883209_3 Serine hydroxymethyltransferase K00600 - 2.1.2.1 0.00000000000000000000003926 100.0
HFD2_k127_3883209_4 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000089 51.0
HFD2_k127_3886295_0 Protein of unknown function (DUF1194) - - - 0.00000000000000000000000001709 113.0
HFD2_k127_3886295_1 TadE-like protein - - - 0.00000000002975 68.0
HFD2_k127_3886295_2 Flp pilus assembly protein TadG - - - 0.00006764 51.0
HFD2_k127_3887196_0 Amidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005538 346.0
HFD2_k127_3887196_1 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003857 317.0
HFD2_k127_3887196_2 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000004288 190.0
HFD2_k127_3887196_3 Endoribonuclease L-PSP - - - 0.000000000000000000000001072 108.0
HFD2_k127_3900007_0 secondary active sulfate transmembrane transporter activity K06901 - - 1.108e-199 634.0
HFD2_k127_3900007_1 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 365.0
HFD2_k127_3900007_2 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000001029 287.0
HFD2_k127_3900007_3 PFAM Phosphoglycerate mutase K22305 - 3.1.3.3 0.0000000000000000000000000000000000000003293 157.0
HFD2_k127_390810_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006533 548.0
HFD2_k127_390810_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006636 364.0
HFD2_k127_390810_2 Histone deacetylase domain K04768 - - 0.0000002747 55.0
HFD2_k127_3921047_0 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004917 280.0
HFD2_k127_3921047_1 alcohol dehydrogenase - - - 0.0000002628 55.0
HFD2_k127_3921047_2 TIM-barrel fold metal-dependent hydrolase - - - 0.00005496 50.0
HFD2_k127_3987912_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001371 282.0
HFD2_k127_3987912_1 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000001777 198.0
HFD2_k127_3987912_2 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.000000000000000000000000000001148 129.0
HFD2_k127_3991705_0 dienelactone hydrolase K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000001779 202.0
HFD2_k127_3991705_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.00000000000000000000000000000000000000000000000005264 194.0
HFD2_k127_3991705_2 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000001313 157.0
HFD2_k127_3991705_3 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.000000000000000000000000000000000001389 147.0
HFD2_k127_3991705_4 - - - - 0.00000000000000000008822 94.0
HFD2_k127_3991705_5 Regulatory protein, FmdB - - - 0.0000001829 55.0
HFD2_k127_4001305_0 Belongs to the ALAD family K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005299 463.0
HFD2_k127_4001305_1 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000008414 252.0
HFD2_k127_4001305_2 PFAM Bacterial regulatory proteins, crp family K10914 - - 0.00000000000000006462 94.0
HFD2_k127_4001305_3 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000002125 85.0
HFD2_k127_4001305_4 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018065,GO:0018130,GO:0018160,GO:0018193,GO:0018198,GO:0019438,GO:0019538,GO:0033013,GO:0033014,GO:0034641,GO:0036211,GO:0042168,GO:0042440,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000001281 69.0
HFD2_k127_4001305_5 Cytochrome C' - - - 0.000000007842 63.0
HFD2_k127_4001305_6 Redoxin - - - 0.0000001051 57.0
HFD2_k127_4001305_7 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000001483 52.0
HFD2_k127_4010176_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1431.0
HFD2_k127_4041141_0 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 604.0
HFD2_k127_4041141_1 Amidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 447.0
HFD2_k127_4041141_2 [2Fe-2S] binding domain - - - 0.0000000000000000000000000000000000000000000000000000005957 198.0
HFD2_k127_4041141_3 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000001102 194.0
HFD2_k127_4041141_4 COG0402 Cytosine deaminase and related metal-dependent hydrolases - - - 0.000000000000000000000000000000000001161 144.0
HFD2_k127_4041141_5 amine dehydrogenase activity - - - 0.000000000000000000000000000000009472 135.0
HFD2_k127_4061059_0 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 351.0
HFD2_k127_4061059_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000003189 129.0
HFD2_k127_4061059_2 Activates fatty acids by binding to coenzyme A K01897 - 6.2.1.3 0.000000000001522 79.0
HFD2_k127_406111_0 Sodium:sulfate symporter transmembrane region - - - 0.000000000000000000000000000000000000000000000000001594 203.0
HFD2_k127_406111_1 ABC transporter substrate binding protein K01989 - - 0.000000000005922 70.0
HFD2_k127_4069599_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 1.526e-254 796.0
HFD2_k127_4069599_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006556 452.0
HFD2_k127_4069599_2 Amino acid permease - - - 0.00000000000000000000000000000000000000007279 155.0
HFD2_k127_4076227_0 Penicillin-binding protein 2 K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 548.0
HFD2_k127_4076227_1 Rod shape-determining protein K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004071 377.0
HFD2_k127_4076227_2 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 350.0
HFD2_k127_4076227_3 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000001069 182.0
HFD2_k127_4076227_4 shape-determining protein K03571 - - 0.0002177 51.0
HFD2_k127_4085654_0 Protease Do-like 1 - GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006091,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0009719,GO:0009725,GO:0009735,GO:0009765,GO:0009987,GO:0010033,GO:0010206,GO:0015979,GO:0016020,GO:0016787,GO:0017171,GO:0019538,GO:0019684,GO:0030091,GO:0030163,GO:0031976,GO:0031977,GO:0031984,GO:0034357,GO:0042221,GO:0042651,GO:0042802,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0050896,GO:0055035,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 297.0
HFD2_k127_4085654_1 Transposase - - - 0.000000000000000000000000000002643 121.0
HFD2_k127_4085654_2 Membrane - - - 0.000000000003126 79.0
HFD2_k127_4085654_3 PFAM PhoH family protein K06217 - - 0.000008385 50.0
HFD2_k127_4085654_4 PhoH-like protein K06217 - - 0.0000168 47.0
HFD2_k127_4102944_0 Sugar fermentation stimulation protein K06206 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002815 273.0
HFD2_k127_4102944_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000003942 179.0
HFD2_k127_4102944_2 Major Facilitator Superfamily - - - 0.0007563 44.0
HFD2_k127_4112446_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07306,K08352 - 1.8.5.3,1.8.5.5 3.079e-201 653.0
HFD2_k127_4112446_1 NMT1-like family - - - 0.0000001697 60.0
HFD2_k127_41160_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007307 421.0
HFD2_k127_41160_1 NMT1-like family K02051 - - 0.000000001384 69.0
HFD2_k127_41160_2 Enoyl-CoA hydratase/isomerase K18383 - 4.1.2.41,4.2.1.101 0.0002582 46.0
HFD2_k127_4124033_0 FecR protein - - - 1.368e-208 668.0
HFD2_k127_4124033_1 COG0044 Dihydroorotase and related cyclic amidohydrolases K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006309 479.0
HFD2_k127_4124033_2 Binding-protein-dependent transport system inner membrane component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003092 409.0
HFD2_k127_4124033_3 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006385 361.0
HFD2_k127_4124033_4 iron ion homeostasis K02012 - - 0.00000000000000000000000000000000000000005865 164.0
HFD2_k127_4124033_5 PFAM pyridoxamine 5'-phosphate oxidase-related - - - 0.00000000000000004227 84.0
HFD2_k127_4127900_0 Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase K11540 GO:0000050,GO:0000052,GO:0000166,GO:0001882,GO:0001884,GO:0002119,GO:0002134,GO:0002164,GO:0003674,GO:0003824,GO:0004070,GO:0004087,GO:0004088,GO:0004151,GO:0004672,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005829,GO:0006082,GO:0006139,GO:0006206,GO:0006207,GO:0006213,GO:0006220,GO:0006221,GO:0006228,GO:0006464,GO:0006468,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007275,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009605,GO:0009653,GO:0009719,GO:0009725,GO:0009791,GO:0009887,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0016053,GO:0016301,GO:0016310,GO:0016363,GO:0016597,GO:0016740,GO:0016741,GO:0016743,GO:0016772,GO:0016773,GO:0016787,GO:0016810,GO:0016812,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0017144,GO:0018107,GO:0018130,GO:0018193,GO:0018210,GO:0019103,GO:0019240,GO:0019438,GO:0019538,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0019899,GO:0022612,GO:0030424,GO:0030554,GO:0031406,GO:0031667,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0032868,GO:0032991,GO:0033267,GO:0034399,GO:0034404,GO:0034641,GO:0034654,GO:0035295,GO:0035639,GO:0036094,GO:0036211,GO:0036477,GO:0042221,GO:0042455,GO:0042594,GO:0042802,GO:0042995,GO:0043005,GO:0043025,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043195,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043434,GO:0043436,GO:0043603,GO:0043604,GO:0043679,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044297,GO:0044306,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044456,GO:0044463,GO:0044464,GO:0045202,GO:0046051,GO:0046112,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046394,GO:0046483,GO:0046777,GO:0046872,GO:0046914,GO:0048513,GO:0048565,GO:0048731,GO:0048732,GO:0048856,GO:0050896,GO:0055086,GO:0055123,GO:0060465,GO:0070013,GO:0070335,GO:0070406,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:0097458,GO:0098793,GO:0120025,GO:0120038,GO:0140096,GO:0150034,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901652,GO:1901657,GO:1901659,GO:1901698,GO:1901700,GO:1905905 2.1.3.2,3.5.2.3,6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005853 458.0
HFD2_k127_4127900_1 Protein of unknown function (DUF1653) K03574 - 3.6.1.55 0.0000000000000000000000000000000000005311 143.0
HFD2_k127_4127900_2 TIGRFAM isocitrate dehydrogenase, NADP-dependent, prokaryotic type K00031 - 1.1.1.42 0.0000000000000009852 78.0
HFD2_k127_4127900_3 DMT(Drug metabolite transporter) superfamily permease - - - 0.00000000000002089 76.0
HFD2_k127_4128336_0 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004 406.0
HFD2_k127_4133374_0 LVIVD repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005616 411.0
HFD2_k127_4133374_1 Enoyl-(Acyl carrier protein) reductase K00059,K00068 - 1.1.1.100,1.1.1.140 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001591 274.0
HFD2_k127_4133374_2 Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively K04099,K04101 - 1.13.11.57,1.13.11.8 0.00000000000000000000000000000008157 132.0
HFD2_k127_4144795_0 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000004449 205.0
HFD2_k127_4144795_1 PFAM ABC transporter related K02049 - - 0.00000000000000000000000000000000000000001099 158.0
HFD2_k127_4144795_2 Belongs to the multicopper oxidase YfiH RL5 family K05810 GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0030312,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0046983,GO:0055114,GO:0071944 - 0.00000000000000000000002576 103.0
HFD2_k127_41699_0 (ABC) transporter K06147,K18890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 559.0
HFD2_k127_41699_1 GTP-binding protein TypA K06207 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 529.0
HFD2_k127_41699_2 ABC transporter transmembrane K18889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008631 475.0
HFD2_k127_4175294_0 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004707 344.0
HFD2_k127_4175294_1 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 319.0
HFD2_k127_4175294_2 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000001133 179.0
HFD2_k127_4175294_3 alpha beta - - - 0.000001866 52.0
HFD2_k127_4178290_0 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 544.0
HFD2_k127_4178290_1 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000001711 208.0
HFD2_k127_4178290_2 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000001977 151.0
HFD2_k127_4178290_3 - - - - 0.000000007817 60.0
HFD2_k127_4178290_4 TRAP-type C4-dicarboxylate transport system, periplasmic component K11688,K21395 - - 0.00006446 52.0
HFD2_k127_4178290_5 NMT1-like family K15576,K22067 - - 0.0006382 49.0
HFD2_k127_4183654_0 Aldehyde dehydrogenase family K00294 - 1.2.1.88 2.428e-218 689.0
HFD2_k127_4183654_1 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000258 183.0
HFD2_k127_4183654_2 PFAM Transglycosylase-associated protein - - - 0.000000000000000000000000000007618 122.0
HFD2_k127_4194298_0 Glycosyl transferase, family 9 K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000004237 248.0
HFD2_k127_4194298_1 dTDP-4-dehydrorhamnose reductase K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000001224 211.0
HFD2_k127_4194298_2 lipopolysaccharide heptosyltransferase K02841,K02843 - - 0.000000000000000000000000000000000000000000000006057 184.0
HFD2_k127_4194298_3 kinase activity - - - 0.000000000000000000000000265 116.0
HFD2_k127_4194298_4 Belongs to the UPF0434 family K09791 - - 0.000000000000000000000001468 103.0
HFD2_k127_4194298_5 kinase activity - - - 0.00000000000000000004384 100.0
HFD2_k127_420332_0 Amino acid permease K11584 GO:0002376,GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006520,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0006928,GO:0006950,GO:0008150,GO:0008152,GO:0008509,GO:0008514,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015203,GO:0015291,GO:0015297,GO:0015318,GO:0015695,GO:0015696,GO:0015711,GO:0015807,GO:0015839,GO:0015846,GO:0015849,GO:0016020,GO:0016021,GO:0016043,GO:0016477,GO:0019752,GO:0022607,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0040011,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0048870,GO:0050896,GO:0050900,GO:0051179,GO:0051234,GO:0051674,GO:0055085,GO:0065003,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0098656,GO:1901564,GO:1902047,GO:1902475,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000834 320.0
HFD2_k127_4223012_0 FAD dependent oxidoreductase K00109,K15736 - 1.1.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 486.0
HFD2_k127_4223012_1 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.0000000000000000000000000006184 119.0
HFD2_k127_4255862_0 S-adenosylmethionine synthetase (AdoMet synthetase) K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 434.0
HFD2_k127_4255862_1 RNA-3'-phosphate cyclase activity K01974 GO:0003674,GO:0003824,GO:0003963,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009975,GO:0016874,GO:0016886,GO:0044424,GO:0044464,GO:0140098 6.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 338.0
HFD2_k127_4255862_2 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 291.0
HFD2_k127_4255862_3 cytochrome - - - 0.00000000000000000000000007464 112.0
HFD2_k127_4258050_0 Conserved carboxylase domain K01571 - 4.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 312.0
HFD2_k127_4258050_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000002672 188.0
HFD2_k127_4258050_2 NMT1-like family K07080 - - 0.000000000000000000000000000000000009508 149.0
HFD2_k127_4268875_0 Binding-protein-dependent transport system inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 477.0
HFD2_k127_4268875_1 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 393.0
HFD2_k127_4268875_2 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004937 335.0
HFD2_k127_4268875_3 CO dehydrogenase flavoprotein domain protein K03519 - 1.2.5.3 0.0000000000000000000473 94.0
HFD2_k127_4268875_4 GntR family - - - 0.000000000000001832 80.0
HFD2_k127_429931_0 Putative ATP-binding cassette K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009772 366.0
HFD2_k127_429931_1 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002951 295.0
HFD2_k127_429931_2 PFAM transglutaminase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009538 260.0
HFD2_k127_429931_3 Phospholipase K06999 - - 0.0000000000000000000000000000000253 134.0
HFD2_k127_429931_4 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000000007062 126.0
HFD2_k127_429931_5 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.0000000000000000001294 91.0
HFD2_k127_4322780_0 PFAM Coenzyme A transferase K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000002989 260.0
HFD2_k127_4322780_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000007713 231.0
HFD2_k127_4322780_2 Ornithine cyclodeaminase K01750 - 4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000001562 228.0
HFD2_k127_4324795_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.18 5.351e-287 890.0
HFD2_k127_4324795_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004645 354.0
HFD2_k127_4324795_2 Membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.00000000000000000000000001337 122.0
HFD2_k127_4387552_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 1.076e-201 637.0
HFD2_k127_4387552_1 Conserved carboxylase domain K01571 - 4.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007177 381.0
HFD2_k127_4387552_2 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004976 273.0
HFD2_k127_4387552_3 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000002885 274.0
HFD2_k127_4387552_4 Phosphoglycerate mutase family K15634 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000008735 229.0
HFD2_k127_4390950_0 PFAM ABC transporter related K01990,K19340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 310.0
HFD2_k127_4390950_1 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001858 263.0
HFD2_k127_4390950_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily K03216 - 2.1.1.207 0.0000000000000000000000000000000000000000000000000001247 189.0
HFD2_k127_4390950_3 PFAM NPCBM-associated, NEW3 domain of alpha-galactosidase - - - 0.000000000000000000000000000000000000000000000000003549 197.0
HFD2_k127_4390950_4 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106026,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.0000000000001462 71.0
HFD2_k127_4390950_5 3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity K03182 - 4.1.1.98 0.0000000001368 63.0
HFD2_k127_4401434_0 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000001634 218.0
HFD2_k127_4401434_1 glycolate biosynthetic process K01091 - 3.1.3.18 0.000001229 52.0
HFD2_k127_4409027_0 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000001344 144.0
HFD2_k127_4409027_1 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000004571 96.0
HFD2_k127_4409027_2 protein conserved in bacteria - - - 0.00000000000000001233 87.0
HFD2_k127_4409027_3 Catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia K01426 - 3.5.1.4 0.00004089 48.0
HFD2_k127_4409027_4 Metallopeptidase family M24 K01271 - 3.4.13.9 0.0005692 43.0
HFD2_k127_4425680_0 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 469.0
HFD2_k127_4425680_1 carbon starvation protein CstA K06200 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 446.0
HFD2_k127_4425680_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000002926 247.0
HFD2_k127_4425680_3 Histone methylation protein DOT1 - - - 0.00000000000000000000000000000000000000000000000000000025 200.0
HFD2_k127_4425680_4 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000000000000000000000000000000000000009876 186.0
HFD2_k127_4425680_5 - - - - 0.000000000000000000000000000000001502 132.0
HFD2_k127_4425680_6 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000155 137.0
HFD2_k127_4425680_7 - - - - 0.00000000000000002198 87.0
HFD2_k127_4425680_8 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000002902 75.0
HFD2_k127_4425680_9 Transcription factor zinc-finger K09981 - - 0.0000000000005343 73.0
HFD2_k127_4430975_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 443.0
HFD2_k127_4430975_1 Belongs to the thiolase family K02615 - 2.3.1.174,2.3.1.223 0.000000000000101 70.0
HFD2_k127_4430975_2 Protein involved in outer membrane biogenesis K07289 - - 0.0000000009352 72.0
HFD2_k127_4432504_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 319.0
HFD2_k127_4432504_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000004266 259.0
HFD2_k127_4432504_2 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.000000000000000000000000000000000000000000000000000000000000000000000001768 252.0
HFD2_k127_4432504_3 TIGRFAM phosphate phosphite phosphonate ABC transporters, periplasmic binding protein K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000001114 235.0
HFD2_k127_4432504_4 PFAM binding-protein-dependent transport systems inner membrane component K02042 - - 0.00000000000000000000000000000000000000000000000000000000000007038 225.0
HFD2_k127_4432504_5 Thioesterase superfamily K10806 - - 0.00000000000000000000000000000006371 128.0
HFD2_k127_4432504_6 Tetratricopeptide repeat - - - 0.00000000000000000000000005319 118.0
HFD2_k127_4434112_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004803 490.0
HFD2_k127_4434112_1 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000000000000000000000000004702 140.0
HFD2_k127_4434112_2 - - - - 0.00000000000000000000005791 99.0
HFD2_k127_4434112_3 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000004084 53.0
HFD2_k127_4437601_0 glutathione-regulated potassium exporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 477.0
HFD2_k127_4437601_1 FIST_C - - - 0.00000000000000000000000000000000000000001671 168.0
HFD2_k127_4437601_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000002522 115.0
HFD2_k127_4440999_0 acetolactate synthase K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 379.0
HFD2_k127_4440999_1 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000001165 191.0
HFD2_k127_4440999_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000007171 163.0
HFD2_k127_4440999_3 Cytidylate kinase-like family - - - 0.0000000000000000000000000000009475 132.0
HFD2_k127_4454511_0 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002924 270.0
HFD2_k127_4454511_1 ABC transporter, phosphonate, periplasmic substrate-binding protein K02051 - - 0.0000000000000000000000000000000000000000007436 167.0
HFD2_k127_4454511_2 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000162 149.0
HFD2_k127_4454511_3 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000009257 129.0
HFD2_k127_4454511_4 PFAM Conserved carboxylase region K01571,K01960 - 4.1.1.3,6.4.1.1 0.000000003394 63.0
HFD2_k127_447403_0 Cyclodeaminase K01750,K19244 - 1.4.1.1,4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000001024 260.0
HFD2_k127_447403_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01781 - 5.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000002544 255.0
HFD2_k127_447403_2 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000001892 184.0
HFD2_k127_447403_3 ornithine cyclodeaminase K01750,K19244 - 1.4.1.1,4.3.1.12 0.0000000000000000000000000000000000008427 151.0
HFD2_k127_4476220_0 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009543 405.0
HFD2_k127_4476220_1 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 344.0
HFD2_k127_4476220_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000003466 83.0
HFD2_k127_4476220_3 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000001332 65.0
HFD2_k127_448870_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006127 464.0
HFD2_k127_448870_1 Belongs to the UbiD family K01612 - 4.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 415.0
HFD2_k127_448870_2 Pfam Cupin K00450,K11948 - 1.13.11.38,1.13.11.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003882 299.0
HFD2_k127_448870_3 NMT1-like family - - - 0.0000000000000000000000364 111.0
HFD2_k127_448870_4 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000008615 86.0
HFD2_k127_4488981_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 8.6e-273 849.0
HFD2_k127_4488981_1 SMART PDZ DHR GLGF domain protein K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004427 349.0
HFD2_k127_4488981_10 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.00009551 44.0
HFD2_k127_4488981_11 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.0003133 43.0
HFD2_k127_4488981_2 RNA pseudouridylate synthase K06177,K06180 - 5.4.99.23,5.4.99.28,5.4.99.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 295.0
HFD2_k127_4488981_3 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003401 270.0
HFD2_k127_4488981_4 ACT domain K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000001068 237.0
HFD2_k127_4488981_5 MlaD protein K06192 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006869,GO:0008150,GO:0009987,GO:0010876,GO:0016020,GO:0016021,GO:0016043,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071840,GO:0071944,GO:0120009 - 0.00000000000000000000000000000000000000000000000000000000000000005207 239.0
HFD2_k127_4488981_6 paraquat-inducible protein A K03808 - - 0.0000000000000000000000000000000000000000002288 166.0
HFD2_k127_4488981_7 Universal bacterial protein YeaZ K14742 - - 0.000000000000000000000000000000000000000001181 165.0
HFD2_k127_4488981_9 - - - - 0.0000000001697 65.0
HFD2_k127_448947_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 399.0
HFD2_k127_448947_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 299.0
HFD2_k127_448947_2 PFAM glutaredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000496 269.0
HFD2_k127_448947_3 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.00000000000000000000000000004107 132.0
HFD2_k127_4502015_0 MmgE/PrpD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 440.0
HFD2_k127_4502015_1 Transposase K00957,K07497 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000004454 260.0
HFD2_k127_4502015_2 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000000000001963 213.0
HFD2_k127_4504687_0 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 317.0
HFD2_k127_4504687_1 nuclease activity - - - 0.0000000000000000009136 91.0
HFD2_k127_4504687_2 MmgE/PrpD family - - - 0.0000000001797 64.0
HFD2_k127_4505538_0 D-aminoacylase domain protein K01465,K06015 - 3.5.1.81,3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 426.0
HFD2_k127_4505538_1 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 287.0
HFD2_k127_4505538_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.000000000000000000000000000000000000006986 149.0
HFD2_k127_4505538_3 - - - - 0.0000000000000002363 83.0
HFD2_k127_4505538_4 - - - - 0.0000000000006733 75.0
HFD2_k127_4508225_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 451.0
HFD2_k127_4508225_1 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000002605 138.0
HFD2_k127_4508225_2 NMT1-like family K02051 - - 0.000000000001017 79.0
HFD2_k127_4508225_3 PFAM Enoyl-CoA hydratase isomerase K01692 - 4.2.1.17 0.000003583 49.0
HFD2_k127_4516124_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K15372 - 2.6.1.19,2.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003342 507.0
HFD2_k127_4516124_1 PFAM Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 353.0
HFD2_k127_4516124_10 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000000000000000002661 218.0
HFD2_k127_4516124_11 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000002867 183.0
HFD2_k127_4516124_12 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000001002 183.0
HFD2_k127_4516124_13 deacetylase K01452,K16842,K22278 - 3.5.1.104,3.5.1.41,3.5.2.5 0.00000000000000000000000000000000000001765 155.0
HFD2_k127_4516124_14 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.000000000000000000000000001883 123.0
HFD2_k127_4516124_15 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00335,K18331,K22339 - 1.12.1.3,1.17.1.11,1.6.5.3 0.0000000000000002211 82.0
HFD2_k127_4516124_16 SET domain K07117 - - 0.0003663 51.0
HFD2_k127_4516124_2 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K15585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007721 330.0
HFD2_k127_4516124_3 TIM-barrel fold metal-dependent hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 340.0
HFD2_k127_4516124_4 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008104 291.0
HFD2_k127_4516124_5 Family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001122 268.0
HFD2_k127_4516124_6 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01007,K08483 - 2.7.3.9,2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000001984 245.0
HFD2_k127_4516124_7 ABC transporter substrate-binding protein K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000168 246.0
HFD2_k127_4516124_8 Phenylacetate-CoA oxygenase K15512 - 1.14.13.208 0.00000000000000000000000000000000000000000000000000000000000001086 230.0
HFD2_k127_4516124_9 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000008098 218.0
HFD2_k127_4532674_0 Ornithine cyclodeaminase K01750 - 4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000445 229.0
HFD2_k127_4532674_1 NMT1-like family K02051 - - 0.000000000000000000000002991 116.0
HFD2_k127_4532674_2 ornithine cyclodeaminase K01750 - 4.3.1.12 0.00000000000000008015 85.0
HFD2_k127_4542246_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 421.0
HFD2_k127_4542246_1 Cytochrome c K02305 - - 0.00000000000000000000000000000000000000001563 167.0
HFD2_k127_4542246_2 oxidoreductase activity, acting on diphenols and related substances as donors K00411 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.10.2.2 0.000000000000000000000000000001091 130.0
HFD2_k127_4542246_3 Cytochrome C oxidase, mono-heme subunit/FixO - - - 0.0000000000001783 79.0
HFD2_k127_4542246_4 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.9.3.1 0.00000001633 66.0
HFD2_k127_4542246_5 Prolyl oligopeptidase family - - - 0.0007565 51.0
HFD2_k127_4542246_6 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.0009476 50.0
HFD2_k127_455768_0 TIM-barrel fold metal-dependent hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001451 266.0
HFD2_k127_455768_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000163 267.0
HFD2_k127_455768_2 tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000001474 230.0
HFD2_k127_455768_3 TPR repeat - - - 0.00000000000000000000000000000000000000000007267 171.0
HFD2_k127_455768_4 protein conserved in bacteria - - - 0.000000000000000000000006889 108.0
HFD2_k127_455895_0 Belongs to the aldehyde dehydrogenase family K00135,K22445 - 1.2.1.16,1.2.1.20,1.2.1.79,1.2.99.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 469.0
HFD2_k127_455895_1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000633 330.0
HFD2_k127_455895_2 Belongs to the short-chain dehydrogenases reductases (SDR) family K12420 - - 0.0000000000000000000000000000000000000000000000000002925 192.0
HFD2_k127_455895_3 arsenate reductase (glutaredoxin) activity K00537 - 1.20.4.1 0.000000000001109 71.0
HFD2_k127_455895_4 Uncharacterized conserved protein (DUF2294) - - - 0.000000009491 58.0
HFD2_k127_4568878_0 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 367.0
HFD2_k127_4568878_1 COG0451 Nucleoside-diphosphate-sugar epimerases - - - 0.00000000000000000000005882 110.0
HFD2_k127_4568878_2 - - - - 0.0000000000007043 73.0
HFD2_k127_4568878_3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.00000000009453 63.0
HFD2_k127_4571369_0 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 616.0
HFD2_k127_4571369_1 regulation of RNA biosynthetic process - - - 0.00003186 46.0
HFD2_k127_4574767_0 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 456.0
HFD2_k127_4574767_1 Alkaline phosphatase K01113 - 3.1.3.1 0.0000000000000000104 83.0
HFD2_k127_4574767_2 - - - - 0.000000000007728 70.0
HFD2_k127_4574767_3 - - - - 0.0000000001738 67.0
HFD2_k127_4590098_0 N-methylhydantoinase B acetone carboxylase, alpha subunit K01474 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008281 314.0
HFD2_k127_4590098_1 hydrolases or acyltransferases (alpha beta hydrolase superfamily) K18100 - - 0.0000000000000000000000000000000000000000000000000000000000001078 224.0
HFD2_k127_4590098_2 Tyrosine phosphatase family - - - 0.0000000000000000000000001813 112.0
HFD2_k127_4593435_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 595.0
HFD2_k127_4593435_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 527.0
HFD2_k127_4593435_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 393.0
HFD2_k127_4593435_3 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008887 371.0
HFD2_k127_4593435_4 Cytidylyltransferase-like K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.000000000000000000000000000000000000000000000000000000000001358 216.0
HFD2_k127_4593435_5 PFAM Phosphoribosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000003157 205.0
HFD2_k127_4593435_6 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000002944 138.0
HFD2_k127_4593435_7 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000007439 138.0
HFD2_k127_4593435_8 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000000004064 122.0
HFD2_k127_4615122_0 MgsA AAA+ ATPase C terminal K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 443.0
HFD2_k127_4615122_1 - - - - 0.00000000000000000000004018 102.0
HFD2_k127_4619920_0 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 347.0
HFD2_k127_4619920_1 RNA recognition motif - - - 0.0000000000000000000000000000000000000004264 151.0
HFD2_k127_4619920_2 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form - - - 0.00000000000000000799 91.0
HFD2_k127_4619920_3 - - - - 0.00000000000000008691 83.0
HFD2_k127_4619920_5 NAD(P)H-binding - - - 0.0000000000007599 68.0
HFD2_k127_4619920_6 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form - - - 0.00000000007907 70.0
HFD2_k127_4619920_7 Transmembrane secretion effector - - - 0.0000138 49.0
HFD2_k127_4624673_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 582.0
HFD2_k127_4624673_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 573.0
HFD2_k127_4624673_2 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007007 442.0
HFD2_k127_4624673_3 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000000000000002499 213.0
HFD2_k127_4624673_4 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000002212 130.0
HFD2_k127_4624673_5 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000002746 109.0
HFD2_k127_4624673_6 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000004537 62.0
HFD2_k127_4627358_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005975 293.0
HFD2_k127_4627358_1 Ketopantoate reductase PanE/ApbA C terminal - - - 0.0000000000000000000000000000000000000000000000000000001502 207.0
HFD2_k127_4627358_2 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.0000000000000000000000000000002188 136.0
HFD2_k127_4627358_3 TIGRFAM ABC transporter, substrate-binding protein, aliphatic K02051 - - 0.0001975 48.0
HFD2_k127_4636404_0 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 319.0
HFD2_k127_4636404_1 Vitamin k epoxide reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004401 290.0
HFD2_k127_4636404_2 Molybdopterin oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000402 248.0
HFD2_k127_4636404_3 chaperone-mediated protein complex assembly K00373,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.00000000000000000000000000000000000000000029 177.0
HFD2_k127_4636404_4 Transcriptional regulator - - - 0.0000000000000000000306 96.0
HFD2_k127_4636700_0 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007646 450.0
HFD2_k127_4636700_1 Electron transfer flavoprotein K03522,K22432 - 1.3.1.108 0.00000000000000000000000000000000000000000000000002598 196.0
HFD2_k127_4636700_2 Electron transfer flavoprotein domain K03521 - - 0.0000000000000000000000000000000000001565 151.0
HFD2_k127_4641317_0 PFAM CBS domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005209 480.0
HFD2_k127_4641317_1 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000005012 181.0
HFD2_k127_4641317_2 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000915 180.0
HFD2_k127_4641317_3 acetylesterase activity - - - 0.000000000000000000000000001019 119.0
HFD2_k127_4641317_4 Dimerisation domain of Zinc Transporter - - - 0.0000000000517 64.0
HFD2_k127_4641317_5 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.000001164 51.0
HFD2_k127_4641660_0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000004293 206.0
HFD2_k127_4641660_1 Protein of unknown function (DUF3455) - - - 0.0000000000000000000000000000000000001392 147.0
HFD2_k127_4641660_2 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000001682 131.0
HFD2_k127_4641660_3 Protein of unknown function (DUF3606) - - - 0.000000000004367 69.0
HFD2_k127_4650303_0 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002184 277.0
HFD2_k127_4650303_1 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000006818 106.0
HFD2_k127_4656772_0 Protein of unknown function (DUF3108) - - - 0.00000000000003207 83.0
HFD2_k127_4656772_1 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067,K01790 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008831,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019305,GO:0019438,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901576 1.1.1.133,5.1.3.13 0.00000000000279 70.0
HFD2_k127_4656772_2 cheY-homologous receiver domain K03413 - - 0.0000000005974 62.0
HFD2_k127_4666288_0 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 395.0
HFD2_k127_4666288_1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000439 381.0
HFD2_k127_4666288_2 Polymer-forming cytoskeletal - - - 0.00000000000000006401 85.0
HFD2_k127_4666288_3 amidohydrolase K03392 - 4.1.1.45 0.000000000000008559 79.0
HFD2_k127_4679561_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002068 259.0
HFD2_k127_4679561_1 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.00000000000000000000000000000000000000000000002873 178.0
HFD2_k127_4679561_2 Uncharacterised protein family UPF0066 - - - 0.0000000000000000000000000000000000000000000138 168.0
HFD2_k127_4679561_3 signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000001284 177.0
HFD2_k127_4679561_4 Histidine kinase - - - 0.000000000000000000000000000000000008301 158.0
HFD2_k127_4679561_5 response to oxidative stress K04063 - - 0.00000000000000000000000000005496 121.0
HFD2_k127_4679561_6 TLC ATP/ADP transporter K03301 - - 0.0000000000000000000000004365 117.0
HFD2_k127_4679561_7 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000008417 96.0
HFD2_k127_4679561_8 CBS domain K04767 - - 0.00000000000000000002693 102.0
HFD2_k127_469235_0 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000001363 200.0
HFD2_k127_469235_1 Protein of unknown function (DUF445) - - - 0.00000000000000000000000000000000000000000003029 169.0
HFD2_k127_469235_2 Protein of unknown function (DUF2283) - - - 0.000000007668 58.0
HFD2_k127_4703797_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K20447 - 1.17.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 558.0
HFD2_k127_4703797_1 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000004121 205.0
HFD2_k127_4703797_2 CO dehydrogenase flavoprotein C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000009387 214.0
HFD2_k127_4703797_3 - - - - 0.00000000002237 69.0
HFD2_k127_4709613_0 - - - - 0.000000000000000000000000000001674 125.0
HFD2_k127_4709613_1 Carbohydrate-selective porin, OprB family - - - 0.00000000000000000006785 94.0
HFD2_k127_4709613_2 Alpha beta hydrolase - - - 0.000000291 52.0
HFD2_k127_4709613_3 Glycine zipper - - - 0.000008166 53.0
HFD2_k127_4709613_4 Putative peptidoglycan binding domain - - - 0.0000946 50.0
HFD2_k127_4775771_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 4.059e-290 909.0
HFD2_k127_4775771_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 570.0
HFD2_k127_4775771_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 290.0
HFD2_k127_4775771_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000009092 105.0
HFD2_k127_4793495_0 TIGRFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000102 244.0
HFD2_k127_4793495_1 PFAM cytochrome c biogenesis protein, transmembrane region K06196 - - 0.00000000000000000000000003116 111.0
HFD2_k127_4793495_2 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000003688 81.0
HFD2_k127_4809495_0 FMN-dependent dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005817 377.0
HFD2_k127_4809495_2 thiamine-containing compound biosynthetic process K02051 - - 0.00000001341 63.0
HFD2_k127_4809495_3 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.00000001402 66.0
HFD2_k127_48130_0 FeS assembly protein SufB K07033,K09014 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009536,GO:0009842,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840 - 7.086e-278 860.0
HFD2_k127_48130_1 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000352 374.0
HFD2_k127_48130_2 Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000001093 254.0
HFD2_k127_48130_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000002383 136.0
HFD2_k127_48130_4 Transcriptional regulator - - - 0.0000000000000000000005522 101.0
HFD2_k127_4821622_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 496.0
HFD2_k127_4821622_1 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000004145 203.0
HFD2_k127_4821622_2 protein conserved in bacteria - - - 0.000000000000009071 79.0
HFD2_k127_4824082_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000634 435.0
HFD2_k127_4824082_1 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000006224 269.0
HFD2_k127_4824082_2 TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED K07025 - - 0.000000000000000000000000000000000000000000000000000007316 197.0
HFD2_k127_4824082_3 thiolester hydrolase activity K06889 - - 0.000000000000001156 84.0
HFD2_k127_4833818_0 Elements of external origin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007706 545.0
HFD2_k127_4833818_1 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000003028 185.0
HFD2_k127_4833818_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000001266 171.0
HFD2_k127_4836732_0 Orn/Lys/Arg decarboxylase, C-terminal domain K01584 - 4.1.1.19 0.0 1345.0
HFD2_k127_4836732_1 Hydrophobe Amphiphile Efflux-1 (HAE1) Family K03296,K18138 - - 0.0 1326.0
HFD2_k127_4836732_2 Predicted Permease Membrane Region - - - 4.899e-291 901.0
HFD2_k127_4836732_3 Predicted Permease Membrane Region - - - 7.166e-248 776.0
HFD2_k127_4836732_4 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002975 345.0
HFD2_k127_4836732_5 Biotin-lipoyl like K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 333.0
HFD2_k127_4836732_6 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001282 278.0
HFD2_k127_4836732_7 SpoIIAA-like - - - 0.0000000000000000001977 93.0
HFD2_k127_4836732_8 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K02030 - - 0.0000000001229 67.0
HFD2_k127_4836732_9 - - - - 0.000001948 51.0
HFD2_k127_48412_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 391.0
HFD2_k127_48412_1 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001244 263.0
HFD2_k127_48412_2 acyl-CoA transferase carnitine dehydratase K18702 - 2.8.3.19 0.00000000000000000000000000000000000000000000000000000000000006119 228.0
HFD2_k127_48412_3 NMT1-like family K02051,K15551 - - 0.0002688 47.0
HFD2_k127_4849819_0 MMPL family K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004164 383.0
HFD2_k127_4849819_1 Photosynthesis system II assembly factor YCF48 - - - 0.000000000000000000000000000000000000000006031 169.0
HFD2_k127_4849819_2 Outer membrane lipoprotein-sorting protein - - - 0.00002668 51.0
HFD2_k127_4850596_0 PFAM OmpA MotB domain protein K03640 - - 0.00000000000000000000000000000000005084 136.0
HFD2_k127_4850596_1 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000002472 123.0
HFD2_k127_4850596_2 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000175 94.0
HFD2_k127_4850596_3 NMT1-like family K02051,K15551 - - 0.0000002185 62.0
HFD2_k127_4853824_0 Mechanosensitive ion channel K22044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009267 336.0
HFD2_k127_4853824_1 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005685 278.0
HFD2_k127_4853824_2 Major facilitator superfamily - GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.000000000000000000000000000000000000000000000000000002624 205.0
HFD2_k127_4853824_3 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 GO:0003674,GO:0003824,GO:0004322,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0033212,GO:0033214,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0098771 1.16.3.1 0.00000000000000000000000000001873 119.0
HFD2_k127_4853824_4 - - - - 0.0000006982 56.0
HFD2_k127_48619_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 2.264e-216 692.0
HFD2_k127_48619_1 carboxymuconolactone decarboxylase - - - 0.00000000000000000000000000000000000000008246 156.0
HFD2_k127_4862785_0 COGs COG0596 hydrolase or acyltransferase (alpha beta hydrolase superfamily) K01055 - 3.1.1.24 0.00000000000000000000000000000000000000000006957 171.0
HFD2_k127_4862785_1 - - - - 0.0000000000000000000008859 99.0
HFD2_k127_4862785_2 Protein of unknown function (DUF433) - - - 0.000000000000000001237 87.0
HFD2_k127_4862785_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K15372 - 2.6.1.19,2.6.1.55 0.00000000000000003095 84.0
HFD2_k127_4862785_4 DnaJ molecular chaperone homology domain - - - 0.000000000889 63.0
HFD2_k127_4862785_5 - - - - 0.0000002613 61.0
HFD2_k127_4862785_6 Alpha beta hydrolase fold - - - 0.000003205 51.0
HFD2_k127_4881896_0 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009672 554.0
HFD2_k127_4881896_1 Mediates influx of magnesium ions K03284,K16074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006357 473.0
HFD2_k127_4881896_10 Belongs to the enoyl-CoA hydratase isomerase family K18383 - 4.1.2.41,4.2.1.101 0.000000000000000000000000000048 128.0
HFD2_k127_4881896_11 photosynthesis - - - 0.000000000000002671 83.0
HFD2_k127_4881896_12 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000105 50.0
HFD2_k127_4881896_13 Alpha/beta hydrolase family - - - 0.000392 44.0
HFD2_k127_4881896_2 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005408 457.0
HFD2_k127_4881896_3 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 362.0
HFD2_k127_4881896_4 Protein of unknown function (DUF1003) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 331.0
HFD2_k127_4881896_5 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 295.0
HFD2_k127_4881896_6 PFAM 2-nitropropane dioxygenase NPD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001236 290.0
HFD2_k127_4881896_7 Belongs to the enoyl-CoA hydratase isomerase family K18383 - 4.1.2.41,4.2.1.101 0.0000000000000000000000000000000000000000000000000000000000000000006476 237.0
HFD2_k127_4881896_8 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000000000002624 205.0
HFD2_k127_4881896_9 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000008981 164.0
HFD2_k127_4883539_0 Belongs to the UbiD family K03182 - 4.1.1.98 3.142e-194 619.0
HFD2_k127_4883539_1 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007645 323.0
HFD2_k127_4883539_2 UbiA prenyltransferase family K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004017 281.0
HFD2_k127_4883539_3 peptidyl-tyrosine sulfation - - - 0.00000000001112 69.0
HFD2_k127_4904336_0 Type I secretion system ABC transporter, HlyB family K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 476.0
HFD2_k127_4917626_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 1.792e-208 676.0
HFD2_k127_4917626_1 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 479.0
HFD2_k127_4917626_2 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 430.0
HFD2_k127_4917626_3 Peptidase M16 K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 384.0
HFD2_k127_4917626_4 Tripartite tricarboxylate transporter TctA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006159 280.0
HFD2_k127_4917626_5 Response regulator receiver - - - 0.00000000000000000000003345 107.0
HFD2_k127_4917626_6 MmgE/PrpD family - - - 0.000000000001958 69.0
HFD2_k127_4919818_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004558 569.0
HFD2_k127_4919818_1 Benzoate membrane transport protein K05782 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005138 392.0
HFD2_k127_4919818_2 Methionine synthase K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 380.0
HFD2_k127_4919818_3 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000001245 184.0
HFD2_k127_4919818_4 Asp/Glu/Hydantoin racemase K01799 - 5.2.1.1 0.0000000000000000000000000000000000000000362 160.0
HFD2_k127_4919818_5 Transcriptional - - - 0.00000000000000000000000000000002241 128.0
HFD2_k127_4919818_6 Subtilase family - - - 0.0006958 50.0
HFD2_k127_4938162_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 436.0
HFD2_k127_4948221_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000481 438.0
HFD2_k127_4948221_1 PFAM peptidase S1 and S6 chymotrypsin Hap - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 417.0
HFD2_k127_4948221_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000006182 144.0
HFD2_k127_4948617_0 ribonuclease Rne Rng family K08300,K08301 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 550.0
HFD2_k127_4948617_1 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001073 271.0
HFD2_k127_4948617_2 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000000005366 151.0
HFD2_k127_4948617_3 RecF/RecN/SMC N terminal domain K03529 - - 0.00000000000000000002218 91.0
HFD2_k127_4948617_4 ORF6N domain - - - 0.000003349 51.0
HFD2_k127_4980411_0 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 582.0
HFD2_k127_4980411_1 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 514.0
HFD2_k127_4980411_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005373 420.0
HFD2_k127_4980411_3 ABC transporter K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000001899 243.0
HFD2_k127_4980411_4 Peptidase family M23 K21471 - - 0.0000000000000000000000000000000000000000000000000312 196.0
HFD2_k127_4980411_5 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000000000000000000000000000000000000000886 177.0
HFD2_k127_4980411_6 Domain of unknown function (DUF1932) - - - 0.000002458 54.0
HFD2_k127_4986795_0 ATP dependent DNA ligase C terminal region K01971 - 6.5.1.1 2.684e-256 816.0
HFD2_k127_4986795_1 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001047 258.0
HFD2_k127_4986795_2 TPR repeat - - - 0.000000000000000000000000000000000000000000000000000003323 201.0
HFD2_k127_4999217_0 PFAM asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 586.0
HFD2_k127_4999217_1 Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) K03670 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 501.0
HFD2_k127_4999217_10 - - - - 0.00003354 56.0
HFD2_k127_4999217_2 Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) K03669 GO:0005575,GO:0016020 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003596 417.0
HFD2_k127_4999217_3 Glycosyl transferases group 1 K16697 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 360.0
HFD2_k127_4999217_4 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 340.0
HFD2_k127_4999217_5 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000001525 165.0
HFD2_k127_4999217_6 AAA domain K02450 - - 0.0000000000000000000119 107.0
HFD2_k127_4999217_7 SPTR Glycosyl transferase group 1 - - - 0.00000000003405 75.0
HFD2_k127_4999217_8 Pectate lyase superfamily protein - - - 0.000000002015 70.0
HFD2_k127_4999217_9 Glycosyl transferases group 1 - - - 0.0000001384 63.0
HFD2_k127_5002009_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004063 588.0
HFD2_k127_5002009_1 Binding-protein-dependent transport system inner membrane component K02033,K15585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 425.0
HFD2_k127_5002009_2 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006114 371.0
HFD2_k127_5002009_3 - - - - 0.0000000000000006394 84.0
HFD2_k127_5006124_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 479.0
HFD2_k127_5006124_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.000000000000000000000000000000003021 130.0
HFD2_k127_5006124_2 Belongs to the GcvT family - - - 0.000000000000000000004576 94.0
HFD2_k127_5009737_0 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000465 417.0
HFD2_k127_5009737_1 Lipoprotein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007438 360.0
HFD2_k127_5009737_2 Lipoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 350.0
HFD2_k127_5009737_3 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 301.0
HFD2_k127_5009737_4 Alpha/beta hydrolase of unknown function (DUF1100) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002613 286.0
HFD2_k127_5009737_5 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001068 265.0
HFD2_k127_5009737_6 KR domain K03366 - 1.1.1.304,1.1.1.76 0.0000000000000000000000000000000000000000000000000000000000000008305 227.0
HFD2_k127_5009737_7 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000004524 210.0
HFD2_k127_5009737_8 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000005955 150.0
HFD2_k127_5009737_9 Alpha/beta hydrolase family - - - 0.00000000291 61.0
HFD2_k127_5023951_0 PFAM Prolyl oligopeptidase family - - - 5.806e-283 882.0
HFD2_k127_5035530_0 Conserved carboxylase domain K01571 - 4.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003897 370.0
HFD2_k127_5058239_0 spermidine synthase activity K00797 GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 486.0
HFD2_k127_5058239_1 6-bladed beta-propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 307.0
HFD2_k127_5058239_10 Ethylbenzene dehydrogenase - - - 0.0006667 44.0
HFD2_k127_5058239_2 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000004342 212.0
HFD2_k127_5058239_3 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000000006778 167.0
HFD2_k127_5058239_4 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000006995 115.0
HFD2_k127_5058239_5 photosynthesis - - - 0.0000000000000000000002861 106.0
HFD2_k127_5058239_6 ResB-like family K07399 - - 0.00000000000000005716 93.0
HFD2_k127_5058239_7 Transposase zinc-ribbon domain - - - 0.0000000000000003578 83.0
HFD2_k127_5058239_8 - - - - 0.000000000001983 81.0
HFD2_k127_5058239_9 COG0457 FOG TPR repeat - - - 0.00004554 52.0
HFD2_k127_508536_0 Tripartite tricarboxylate transporter TctA family K07793 - - 6.575e-234 732.0
HFD2_k127_508536_1 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 473.0
HFD2_k127_508536_2 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005403 311.0
HFD2_k127_508536_3 Tripartite tricarboxylate transporter TctB family - - - 0.0000000000000000000000000000000000000000000000919 174.0
HFD2_k127_508536_4 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000000000000000000000000000122 182.0
HFD2_k127_508536_5 Tripartite tricarboxylate transporter family receptor - - - 0.000002343 51.0
HFD2_k127_5127215_0 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway K03707 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 3.5.99.2 0.00000000000000000000000000000000000000000000001843 177.0
HFD2_k127_5127215_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000002867 158.0
HFD2_k127_5156671_0 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004476 341.0
HFD2_k127_5156671_1 AMMECR1 K09141 - - 0.000000000000000000000000000000000000000000001658 171.0
HFD2_k127_5156671_2 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.0000000000000000000000000000000000000004083 152.0
HFD2_k127_5156671_3 methionyl-tRNA aminoacylation K01874,K01890,K06878 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10,6.1.1.20 0.00000000000000000000000000000000005898 139.0
HFD2_k127_5156671_4 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000205 131.0
HFD2_k127_5156671_5 Zn-dependent hydrolases of the - - - 0.00000000000000000000000000000001699 139.0
HFD2_k127_5157152_0 Amino acid ABC transporter substrate-binding protein, PAAT family K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 343.0
HFD2_k127_5157152_1 Acetamidase/Formamidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 311.0
HFD2_k127_5157152_2 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005673 288.0
HFD2_k127_5157152_3 ABC 3 transport family K02075 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007048 271.0
HFD2_k127_5157152_4 Belongs to the bacterial solute-binding protein 9 family K02077,K09815 - - 0.0000000000000000000000000000000000000000000000000000000000000000861 232.0
HFD2_k127_5157152_5 Amino acid ABC transporter substrate-binding protein, PAAT family K02030 - - 0.0000001604 54.0
HFD2_k127_51597_0 Glycogen debranching enzyme - - - 0.0 1661.0
HFD2_k127_51597_1 Alpha amylase, catalytic domain - - - 1.17e-245 766.0
HFD2_k127_51597_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006715 451.0
HFD2_k127_51597_3 Mechanosensitive ion channel K05802 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 391.0
HFD2_k127_51597_4 - - - - 0.00000000000000000000000001084 110.0
HFD2_k127_51597_6 - - - - 0.000946 51.0
HFD2_k127_51632_0 ornithine cyclodeaminase K01750 - 4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003896 326.0
HFD2_k127_51632_1 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000002958 108.0
HFD2_k127_51632_2 Glyoxalase-like domain K08234 - - 0.00002683 55.0
HFD2_k127_5175040_0 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001183 272.0
HFD2_k127_5175040_1 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000006096 271.0
HFD2_k127_5175040_2 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000009175 207.0
HFD2_k127_5175040_3 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000004127 172.0
HFD2_k127_5177096_0 Binding-protein-dependent transport system inner membrane component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 419.0
HFD2_k127_5177096_1 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000007431 160.0
HFD2_k127_5182799_0 FAD binding domain K05898,K13796 - 1.3.99.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 459.0
HFD2_k127_5182799_1 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 377.0
HFD2_k127_5182799_2 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000000166 202.0
HFD2_k127_5223913_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 - 3.4.21.83 3.207e-260 816.0
HFD2_k127_5223913_1 NMT1-like family - - - 0.000000000000000000000000000000001333 142.0
HFD2_k127_52408_0 Sigma-54 interaction domain K07714,K07715 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007407 601.0
HFD2_k127_52408_1 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000005677 231.0
HFD2_k127_52408_2 mannose-1-phosphate guanylyltransferase activity K00971,K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000747 95.0
HFD2_k127_52408_3 - - - - 0.000000000000000001524 87.0
HFD2_k127_52408_4 Alpha-amylase domain K05341,K05343 - 2.4.1.4,3.2.1.1,5.4.99.16 0.00000000001203 65.0
HFD2_k127_52408_5 SMART Transport-associated and nodulation region K04065 - - 0.000001727 54.0
HFD2_k127_52408_6 YtxH-like protein - - - 0.00001857 51.0
HFD2_k127_5246181_0 elongation factor Tu domain 2 protein K02355 - - 9.546e-240 760.0
HFD2_k127_5246181_1 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 336.0
HFD2_k127_5246181_2 HTH domain K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000000002419 231.0
HFD2_k127_5246181_3 Amidohydrolase K03392 - 4.1.1.45 0.000000000000000000000000000000000000000000000003182 186.0
HFD2_k127_5246181_4 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000005781 156.0
HFD2_k127_5246181_5 Amidohydrolase - - - 0.0000000000000007083 89.0
HFD2_k127_5246181_6 - - - - 0.0000000000002243 74.0
HFD2_k127_5263259_0 transport system fused permease components - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005006 379.0
HFD2_k127_5263259_1 TRAP transporter solute receptor TAXI family protein K07080 - - 0.00000000000000000000000000003316 123.0
HFD2_k127_5264686_0 FMN-dependent dehydrogenase K01823 GO:0003674,GO:0003824,GO:0004452,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0071704,GO:1901576 5.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 365.0
HFD2_k127_5264686_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003843 326.0
HFD2_k127_5264686_2 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000004484 252.0
HFD2_k127_5264686_3 Pyridoxamine 5'-phosphate oxidase K09979 - - 0.0000000000000000000000000000000000000004138 153.0
HFD2_k127_5264686_4 Domain of unknown function DUF120 K07732 - 2.7.1.161 0.00000000000000000223 90.0
HFD2_k127_5264686_5 - - - - 0.0000000000008904 74.0
HFD2_k127_5266069_0 protein histidine kinase activity K02484,K11206,K11383 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000001005 208.0
HFD2_k127_5266069_1 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000008207 104.0
HFD2_k127_5278251_0 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003498 267.0
HFD2_k127_5278251_1 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000005849 178.0
HFD2_k127_5278251_2 PFAM KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.00000000000000000000000000000000000001958 152.0
HFD2_k127_5285233_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 7.346e-211 666.0
HFD2_k127_5285233_1 PFAM aspartate glutamate uridylate kinase K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 503.0
HFD2_k127_5285233_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003086 430.0
HFD2_k127_5285233_3 PFAM Uncharacterised P-loop hydrolase UPF0079 K06925 - - 0.000000000000000000000000000000002822 135.0
HFD2_k127_5285233_4 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.000000000004877 66.0
HFD2_k127_5290247_0 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 513.0
HFD2_k127_5290247_1 PFAM thiamine pyrophosphate enzyme-like TPP-binding thiamine pyrophosphate - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 413.0
HFD2_k127_5290247_10 EamA-like transporter family - - - 0.000000000000001756 87.0
HFD2_k127_5290247_11 - - - - 0.0004132 43.0
HFD2_k127_5290247_2 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 396.0
HFD2_k127_5290247_3 PFAM Transketolase central region K00162 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 383.0
HFD2_k127_5290247_4 Dehydrogenase E1 component K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 377.0
HFD2_k127_5290247_5 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit K00162,K11381 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 354.0
HFD2_k127_5290247_6 PFAM dehydrogenase, E1 component K21416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004779 301.0
HFD2_k127_5290247_7 Peptidase family U32 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003651 265.0
HFD2_k127_5290247_8 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000000000000000000000001844 162.0
HFD2_k127_5290247_9 Bacterial-like globin K06886 - - 0.0000000000000000105 83.0
HFD2_k127_5291282_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 526.0
HFD2_k127_5291282_1 CO dehydrogenase flavoprotein C-terminal domain K11178 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004181 283.0
HFD2_k127_5291282_2 PFAM 2Fe-2S -binding K03518,K07302,K13483 - 1.2.5.3,1.3.99.16 0.0000000000000000000000000000000000000000000000000001678 192.0
HFD2_k127_5291282_3 Belongs to the P-Pant transferase superfamily K06133 - - 0.0000000000000000000000000000000000000000003391 165.0
HFD2_k127_5291282_4 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 0.0000005465 61.0
HFD2_k127_5293301_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 1.855e-300 950.0
HFD2_k127_5293301_1 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 617.0
HFD2_k127_5293301_2 alpha/beta hydrolase fold K07019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 372.0
HFD2_k127_5293301_3 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000003742 151.0
HFD2_k127_5299087_0 Alpha/beta hydrolase of unknown function (DUF1100) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 303.0
HFD2_k127_5299087_1 COG0006 Xaa-Pro aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000002907 227.0
HFD2_k127_5299087_2 TRAP transporter solute receptor TAXI family protein K07080 - - 0.0000000000000000000000000000000000000000003053 171.0
HFD2_k127_5299087_3 Bacterial periplasmic substrate-binding proteins - - - 0.000000000000000000000000000000000002618 151.0
HFD2_k127_5299087_4 - - - - 0.0000000000000000000001331 99.0
HFD2_k127_5299087_5 PFAM Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000003129 97.0
HFD2_k127_5299087_6 ACT domain - - - 0.00000000000001848 79.0
HFD2_k127_5299087_7 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000004653 76.0
HFD2_k127_5299087_8 - - - - 0.000000294 55.0
HFD2_k127_5302005_0 COG4591 ABC-type transport system, involved in lipoprotein release, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007117 486.0
HFD2_k127_5302005_1 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000594 289.0
HFD2_k127_530783_0 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 3.817e-212 673.0
HFD2_k127_530783_1 PFAM ABC transporter related K02049,K15555 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 305.0
HFD2_k127_530783_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004665 298.0
HFD2_k127_530783_3 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000001557 236.0
HFD2_k127_530783_4 PFAM ABC transporter related K02049,K15555,K15578 - - 0.0000000000000000000000000000000000001416 156.0
HFD2_k127_530783_5 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000000008541 113.0
HFD2_k127_530783_6 abc transporter K02049 - - 0.0004742 44.0
HFD2_k127_5308130_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 5.155e-233 740.0
HFD2_k127_5308130_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 357.0
HFD2_k127_5308130_2 Methyltransferase domain - - - 0.00000000000000000000000000000000001466 144.0
HFD2_k127_5308130_3 response regulator - - - 0.000000000000000000003864 98.0
HFD2_k127_5308130_4 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 - 2.1.1.200 0.00000000000000000002733 94.0
HFD2_k127_5308130_5 peptidyl-tyrosine sulfation - - - 0.000000000004026 74.0
HFD2_k127_5308446_0 Protein of unknown function (DUF2950) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001463 260.0
HFD2_k127_5308446_1 (twin-arginine translocation) pathway signal - - - 0.000000000000000000000000000000000000000000000000001102 189.0
HFD2_k127_5308446_2 - - - - 0.000000000000000000000000000000000000115 147.0
HFD2_k127_5308446_3 - - - - 0.0000000000000000000000000000005655 127.0
HFD2_k127_5308446_4 Belongs to the ompA family - - - 0.000000000000000003073 94.0
HFD2_k127_5308446_5 Mechanosensitive ion channel - - - 0.000007015 53.0
HFD2_k127_5311776_0 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 339.0
HFD2_k127_5311776_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004441 348.0
HFD2_k127_5311776_2 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001337 280.0
HFD2_k127_5311776_3 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009858 276.0
HFD2_k127_5311776_4 NMT1/THI5 like K02051 - - 0.00000000000000004793 93.0
HFD2_k127_5313496_0 Tripartite tricarboxylate transporter TctA family K07793 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 612.0
HFD2_k127_5313496_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000002581 269.0
HFD2_k127_5313496_2 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000005506 221.0
HFD2_k127_5313496_3 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000001749 213.0
HFD2_k127_5313496_4 Protein of unknown function (DUF456) K09793 - - 0.00000000000000000000000000000000000000000000000003598 183.0
HFD2_k127_5313496_5 Tripartite tricarboxylate transporter TctB family K07794 - - 0.0000000000000000004082 93.0
HFD2_k127_5313496_6 Lactoylglutathione lyase K01759 GO:0003674,GO:0003824,GO:0004462,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016151,GO:0016829,GO:0016846,GO:0019243,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042182,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0046872,GO:0046914,GO:0051186,GO:0051596,GO:0061727,GO:0071704,GO:1901564,GO:1901575,GO:1901615 4.4.1.5 0.0000000000000006577 77.0
HFD2_k127_5313496_7 - - - - 0.0000004409 57.0
HFD2_k127_531643_0 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 329.0
HFD2_k127_531643_1 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 297.0
HFD2_k127_531643_2 response to heat K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006657 290.0
HFD2_k127_531643_3 COG0665 Glycine D-amino acid oxidases (deaminating) K19746 - 1.4.99.6 0.00000000000000000000000000000000000000000000000000000000000000000007517 244.0
HFD2_k127_5318959_0 glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 1.322e-286 893.0
HFD2_k127_5318959_1 helix_turn_helix ASNC type K03719 - - 0.000000000000000000000000000000000000002692 151.0
HFD2_k127_5324980_0 PFAM glycosyl transferase family 20 K00697,K16055 - 2.4.1.15,2.4.1.347,3.1.3.12 7.132e-262 827.0
HFD2_k127_5324980_1 PFAM glycosyl transferase group 1 K13057 - 2.4.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 572.0
HFD2_k127_5324980_2 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000001703 235.0
HFD2_k127_5324980_3 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000886 219.0
HFD2_k127_5324980_4 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000003521 129.0
HFD2_k127_5324980_5 NMT1-like family K02051 - - 0.000000000000002482 90.0
HFD2_k127_5324980_6 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00009764 46.0
HFD2_k127_533367_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000009394 202.0
HFD2_k127_533367_1 NMT1-like family K02051 - - 0.000006735 53.0
HFD2_k127_5357602_0 Isocitrate lyase K01637 GO:0003674,GO:0003824,GO:0004451,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0006102,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046421,GO:0046487,GO:0071704,GO:0072350 4.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006455 477.0
HFD2_k127_5357602_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000003601 206.0
HFD2_k127_5357602_2 mttA/Hcf106 family K03116,K03117 - - 0.00000000000000001191 85.0
HFD2_k127_5357602_3 - - - - 0.0003215 45.0
HFD2_k127_5363057_0 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 398.0
HFD2_k127_5363057_1 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 343.0
HFD2_k127_5363057_2 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008648 335.0
HFD2_k127_5363057_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 308.0
HFD2_k127_5364177_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1159.0
HFD2_k127_5364177_1 Carbohydrate phosphorylase K00688 - 2.4.1.1 2.852e-241 756.0
HFD2_k127_5364177_2 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000001681 246.0
HFD2_k127_5368682_0 3'-5' exonuclease K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000001373 216.0
HFD2_k127_5368682_1 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000405 93.0
HFD2_k127_5372541_0 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 411.0
HFD2_k127_5372541_1 Histone methylation protein DOT1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007275 314.0
HFD2_k127_5372541_2 TIM-barrel fold metal-dependent hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005672 276.0
HFD2_k127_5372541_3 PAP2 superfamily K12978 - - 0.0000000000000000000000005619 113.0
HFD2_k127_5374776_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 3.883e-243 761.0
HFD2_k127_5374776_1 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000007763 205.0
HFD2_k127_5380741_0 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.0 1130.0
HFD2_k127_53857_0 Binding-protein-dependent transport system inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 508.0
HFD2_k127_53857_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K02052 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 364.0
HFD2_k127_53857_2 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000004913 159.0
HFD2_k127_53857_3 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000000000000002433 138.0
HFD2_k127_53857_4 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.0000000000000002101 83.0
HFD2_k127_5387753_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000005707 240.0
HFD2_k127_5387753_1 transmembrane transporter activity K05820 - - 0.00000000000000000000000000000000000000000000000000000003342 206.0
HFD2_k127_5388200_0 lactate metabolic process - - - 0.000000000000000000000000000000000000000000000000000000000402 209.0
HFD2_k127_5388200_1 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000001832 214.0
HFD2_k127_5388200_2 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.000000000000000000000000000000000000000000000000000006404 203.0
HFD2_k127_5388200_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000005207 192.0
HFD2_k127_5388200_4 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000002403 191.0
HFD2_k127_5388200_5 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000004065 180.0
HFD2_k127_5388200_6 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000004285 160.0
HFD2_k127_5388200_7 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000003866 83.0
HFD2_k127_5391311_0 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955 - 2.7.1.25,2.7.7.4 1.78e-255 802.0
HFD2_k127_5391311_1 TIGRFAM sulfate adenylyltransferase, small subunit K00957 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 462.0
HFD2_k127_5391311_2 synthase K01719 - 4.2.1.75 0.000000000000000000000000000000000000000000000173 172.0
HFD2_k127_5399631_0 ABC-type Fe3 transport system permease component K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 382.0
HFD2_k127_5399631_1 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001762 282.0
HFD2_k127_5400606_0 PFAM amidohydrolase K01464,K01465 - 3.5.2.2,3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005108 396.0
HFD2_k127_5400606_1 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000249 216.0
HFD2_k127_5400606_2 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000007171 141.0
HFD2_k127_5400606_3 ABC-type nitrate sulfonate bicarbonate transport - - - 0.000000000000000000415 93.0
HFD2_k127_5400606_4 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000001182 58.0
HFD2_k127_5406907_0 Belongs to the transketolase family K00615 - 2.2.1.1 0.0 1016.0
HFD2_k127_5406907_1 Phosphoglucose isomerase K00616,K13810 - 2.2.1.2,5.3.1.9 2.779e-310 975.0
HFD2_k127_5406907_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 598.0
HFD2_k127_5406907_3 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007151 421.0
HFD2_k127_5406907_4 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000002101 211.0
HFD2_k127_5406907_5 transferase activity, transferring glycosyl groups K20742 - 3.4.14.13 0.00000000000000000000000000000000000000000000000000000004201 202.0
HFD2_k127_5406907_6 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.000000000000000000000000000000000000000000001285 173.0
HFD2_k127_5406914_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005402 585.0
HFD2_k127_5406914_1 PFAM Cys Met metabolism pyridoxal-phosphate-dependent K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004189 462.0
HFD2_k127_5406914_2 peptidoglycan-binding domain-containing protein - - - 0.000000000001256 79.0
HFD2_k127_5428848_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 6.896e-199 631.0
HFD2_k127_5428848_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00282 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006807,GO:0008150,GO:0008152,GO:0009069,GO:0009987,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019752,GO:0032991,GO:0042133,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901605,GO:1902494,GO:1990204 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 436.0
HFD2_k127_5428848_2 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate K02437 GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 - 0.0000000000000000000000000000000000000000000003077 171.0
HFD2_k127_5428848_3 ECF sigma factor - - - 0.0000000000000000000000000000000000000001211 156.0
HFD2_k127_5428848_4 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000006871 99.0
HFD2_k127_5428848_5 Protein of unknown function (DUF3426) - - - 0.000000000000002817 88.0
HFD2_k127_5428848_6 TIGRFAM TonB K03832 - - 0.0000000000001027 81.0
HFD2_k127_5428848_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system - - - 0.0000001206 56.0
HFD2_k127_5428848_8 Putative zinc-finger - - - 0.0000299 48.0
HFD2_k127_5435207_0 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008427 315.0
HFD2_k127_5435207_1 glycosyl transferase group 1 K13668 - 2.4.1.346 0.000000000000000000000000000000000000000000000000000000000001016 224.0
HFD2_k127_5435207_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000001133 148.0
HFD2_k127_5444576_0 PFAM type II secretion system protein E K02283,K03609 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 552.0
HFD2_k127_5444576_1 diguanylate cyclase K21020 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000001205 227.0
HFD2_k127_5444576_10 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000001492 98.0
HFD2_k127_5444576_11 PFAM peptidase A24A, prepilin type IV - - - 0.0000000000000007259 84.0
HFD2_k127_5444576_12 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.000002243 57.0
HFD2_k127_5444576_2 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000004357 213.0
HFD2_k127_5444576_3 Pilus formation protein N terminal region K02280 - - 0.00000000000000000000000000000000000000000000000000001454 210.0
HFD2_k127_5444576_4 AAA domain K02282 - - 0.0000000000000000000000000000000000000000000000003273 191.0
HFD2_k127_5444576_5 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000008251 179.0
HFD2_k127_5444576_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000006328 181.0
HFD2_k127_5444576_7 PFAM Type II secretion system F K12511 - - 0.000000000000000000000000000000000000000000001379 177.0
HFD2_k127_5444576_8 PFAM Type II secretion system F K12510 - - 0.000000000000000000000000000000000000000009986 168.0
HFD2_k127_5444576_9 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.0000000000000000000000000000000000000006062 159.0
HFD2_k127_5452092_0 Peptidogalycan biosysnthesis/recognition K09919 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 344.0
HFD2_k127_5452092_1 Branched-chain-amino-acid aminotransferase-like protein 3 K18482 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008153,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0019438,GO:0019752,GO:0032787,GO:0042537,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046482,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 337.0
HFD2_k127_5452092_2 ornithine cyclodeaminase K01750 - 4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003994 338.0
HFD2_k127_5452092_3 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.00000000000000000000000000000000000226 141.0
HFD2_k127_5452092_4 Protein of unknown function (DUF1178) - - - 0.0000000000000000000000000029 121.0
HFD2_k127_5462303_0 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006098 437.0
HFD2_k127_5462303_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000007245 51.0
HFD2_k127_5477838_0 NAD binding K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 484.0
HFD2_k127_5477838_1 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 331.0
HFD2_k127_5477838_2 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000000008669 194.0
HFD2_k127_5477838_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000000000145 165.0
HFD2_k127_5477838_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.6.5.3 0.00000000000000000000000000000000001248 139.0
HFD2_k127_5480322_0 histidine kinase A domain protein - - - 0.0000000000000000000000005613 119.0
HFD2_k127_5482980_0 Pfam SNARE associated Golgi protein - - - 3.012e-216 692.0
HFD2_k127_5482980_1 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006131 361.0
HFD2_k127_5482980_2 Endonuclease Exonuclease Phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000003416 250.0
HFD2_k127_5482980_3 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000004417 84.0
HFD2_k127_5488599_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 455.0
HFD2_k127_5488599_1 NMT1-like family K07080 - - 0.0000000000000000000000000000000000002153 153.0
HFD2_k127_549630_0 Tripartite tricarboxylate transporter TctA family K07793 - - 8.974e-196 622.0
HFD2_k127_549630_1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 371.0
HFD2_k127_549630_2 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000007115 214.0
HFD2_k127_549630_3 Belongs to the TPP enzyme family K13039 - 4.1.1.79 0.00000000000000000000000000000000001076 148.0
HFD2_k127_549630_4 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K06034 - 4.1.1.79 0.0000000000000000000000000003547 120.0
HFD2_k127_549630_5 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000000006173 113.0
HFD2_k127_549630_6 PFAM Tripartite tricarboxylate transporter TctB family K07794 - - 0.00000898 54.0
HFD2_k127_5504223_0 ATP-dependent helicase C-terminal K03579 - 3.6.4.13 1.17e-320 1001.0
HFD2_k127_5504223_1 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000002377 198.0
HFD2_k127_5504223_2 PIN domain - - - 0.000000000000000000001219 100.0
HFD2_k127_5512445_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002648 355.0
HFD2_k127_5512445_1 Chromate transporter K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 332.0
HFD2_k127_5514810_0 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 1.345e-227 724.0
HFD2_k127_5514810_1 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 6.799e-210 665.0
HFD2_k127_5514810_2 Conserved carboxylase domain K01571 - 4.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 414.0
HFD2_k127_5514810_3 NMT1-like family - - - 0.000000001085 70.0
HFD2_k127_5514810_4 TIGRFAM aliphatic sulfonates family ABC transporter, periplsmic ligand-binding protein K02051,K15553 - - 0.0000001242 63.0
HFD2_k127_5514977_0 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate K01612 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044464 4.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 377.0
HFD2_k127_5514977_1 DJ-1/PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000004278 169.0
HFD2_k127_5514977_2 Belongs to the UbiD family K03182,K16874 - 4.1.1.98 0.00000000000000000000001098 105.0
HFD2_k127_5514977_3 thiamine-containing compound biosynthetic process K02051 - - 0.00000437 58.0
HFD2_k127_5526777_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688,K18786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.321 0.0 1338.0
HFD2_k127_5526777_1 MTH538 TIR-like domain (DUF1863) - - - 0.00000000000000007296 86.0
HFD2_k127_5561001_0 DNA replication proofreading K02336,K06877,K07501 - 2.7.7.7 5.671e-270 850.0
HFD2_k127_5561001_1 Belongs to the Glu Leu Phe Val dehydrogenases family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 490.0
HFD2_k127_5561001_10 Rieske 2Fe-2S - - - 0.00000000000000000000003621 103.0
HFD2_k127_5561001_11 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases - - - 0.0000000000000000002057 94.0
HFD2_k127_5561001_12 Mo-molybdopterin cofactor biosynthetic process - - - 0.000000207 63.0
HFD2_k127_5561001_2 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 309.0
HFD2_k127_5561001_3 Isochorismatase family K08281 - 3.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000001971 251.0
HFD2_k127_5561001_4 PAC2 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003261 246.0
HFD2_k127_5561001_5 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000002889 225.0
HFD2_k127_5561001_6 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000003121 209.0
HFD2_k127_5561001_7 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000000000000000000000000000000000000000002325 193.0
HFD2_k127_5561001_8 PFAM Histidine triad (HIT) protein K02503 - - 0.00000000000000000000000000000000000000000004296 163.0
HFD2_k127_5561001_9 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.00000000000000000000000000000000000001723 147.0
HFD2_k127_5561744_0 mannose-ethanolamine phosphotransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005022 507.0
HFD2_k127_5561744_1 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 447.0
HFD2_k127_5561744_2 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 366.0
HFD2_k127_5561744_3 - - - - 0.0000000000000000000000000003266 122.0
HFD2_k127_5561744_6 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0003314 43.0
HFD2_k127_5567709_0 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 8.931e-203 647.0
HFD2_k127_5567709_1 Cysteine-rich domain K11473,K21834 - - 1.866e-197 635.0
HFD2_k127_5567709_2 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 404.0
HFD2_k127_5567709_3 electron transfer flavoprotein K03522,K22432 - 1.3.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000004452 265.0
HFD2_k127_5567709_4 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000009353 248.0
HFD2_k127_5567709_5 electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000005911 228.0
HFD2_k127_5567709_6 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000006983 203.0
HFD2_k127_5567709_7 NMT1-like family - - - 0.0000000000000000000000006845 116.0
HFD2_k127_5567709_8 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000001135 104.0
HFD2_k127_5569648_0 TIM-barrel fold metal-dependent hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000007362 247.0
HFD2_k127_5569648_1 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000007687 85.0
HFD2_k127_5569648_2 Belongs to the TPP enzyme family K01576,K01652 - 2.2.1.6,4.1.1.7 0.000002897 49.0
HFD2_k127_5569736_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.225e-248 777.0
HFD2_k127_5569736_1 Asparaginase - - - 1.714e-201 642.0
HFD2_k127_5569736_10 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001661 275.0
HFD2_k127_5569736_11 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000006775 197.0
HFD2_k127_5569736_12 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.000000000000000000000000000000000000000000000002878 178.0
HFD2_k127_5569736_13 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000247 181.0
HFD2_k127_5569736_14 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.00000000000000000000000000000000000000006925 163.0
HFD2_k127_5569736_15 Pilus assembly protein PilX K02673 - - 0.00000000000000000000000001324 123.0
HFD2_k127_5569736_16 Pfam:N_methyl_2 - - - 0.00000000000000000000000008691 114.0
HFD2_k127_5569736_17 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000000000002018 102.0
HFD2_k127_5569736_18 Phosphotransferase System K11189 - - 0.0000000000000000000125 96.0
HFD2_k127_5569736_19 Hydantoin racemase K16841 - 5.1.99.3 0.000000000000000009321 93.0
HFD2_k127_5569736_2 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 605.0
HFD2_k127_5569736_20 OstA-like protein K09774 - - 0.00000000000001075 81.0
HFD2_k127_5569736_22 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.0000000101 67.0
HFD2_k127_5569736_23 type IV pilus modification protein PilV K02458,K02671 - - 0.00000001416 62.0
HFD2_k127_5569736_24 - - - - 0.000001122 58.0
HFD2_k127_5569736_25 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.0002003 45.0
HFD2_k127_5569736_26 Lipopolysaccharide-assembly, LptC-related - - - 0.0002641 51.0
HFD2_k127_5569736_3 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 549.0
HFD2_k127_5569736_4 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007604 453.0
HFD2_k127_5569736_5 SIS domain K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006186 387.0
HFD2_k127_5569736_6 Belongs to the KdsA family K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000046 359.0
HFD2_k127_5569736_7 PFAM ABC transporter related K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 309.0
HFD2_k127_5569736_8 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004915 307.0
HFD2_k127_5569736_9 Nitrile hydratase, alpha chain K01721 - 4.2.1.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005311 291.0
HFD2_k127_5578739_0 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 304.0
HFD2_k127_5578739_1 S1 P1 nuclease K05986 - 3.1.30.1 0.0000000000000000000000000000000000000003206 160.0
HFD2_k127_5578739_2 Protein of Unknown function (DUF2784) - - - 0.0000000000000000000000000000000000002261 144.0
HFD2_k127_5578739_3 Phenylacetate-CoA oxygenase K02609 - 1.14.13.149 0.000000000000000000000000000000004024 137.0
HFD2_k127_5595229_0 Conserved carboxylase domain K01571 - 4.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 385.0
HFD2_k127_5599122_0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005285 565.0
HFD2_k127_5599122_1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000003888 239.0
HFD2_k127_5606162_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005819 516.0
HFD2_k127_5606162_1 Acetolactate synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000002319 256.0
HFD2_k127_5606162_3 Cupin domain - - - 0.00000000000000000000000000000000000000000000007933 174.0
HFD2_k127_5606162_4 Mannose-6-phosphate isomerase - - - 0.0000000000000000000000000000000000000247 147.0
HFD2_k127_5606162_5 Periplasmic or secreted lipoprotein - - - 0.000000000000000000009335 94.0
HFD2_k127_5606162_6 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.000000000000002444 79.0
HFD2_k127_5608040_0 Domain of unknown function (DUF3552) K18682 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005879 612.0
HFD2_k127_5608040_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 488.0
HFD2_k127_5608040_2 PFAM Metallophosphoesterase K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006377 291.0
HFD2_k127_5608040_4 - - - - 0.00000000002503 63.0
HFD2_k127_560980_0 CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 377.0
HFD2_k127_560980_1 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 318.0
HFD2_k127_560980_2 UDP binding domain K02474,K13015 - 1.1.1.136 0.000000001428 59.0
HFD2_k127_560980_3 Regulatory protein, FmdB - - - 0.0000639 48.0
HFD2_k127_5609851_0 nitrate reductase beta subunit K00371,K17051 - 1.7.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007209 355.0
HFD2_k127_5609851_1 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007398 301.0
HFD2_k127_5609851_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000007896 228.0
HFD2_k127_5609851_4 chaperone-mediated protein complex assembly - - - 0.00000000000000000000000000005517 132.0
HFD2_k127_5609851_5 - - - - 0.0000000000002768 75.0
HFD2_k127_5609851_6 component of anaerobic K03533 - - 0.0006078 51.0
HFD2_k127_5609891_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 484.0
HFD2_k127_5609891_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006245 460.0
HFD2_k127_5609891_2 Two component, sigma54 specific, transcriptional regulator, Fis family K02667,K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 380.0
HFD2_k127_5609891_3 AAA domain K07028 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009576 351.0
HFD2_k127_5609891_4 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000000000007429 166.0
HFD2_k127_5609891_5 Transcriptional regulator - - - 0.0000000000000000000000000000000000000156 156.0
HFD2_k127_5609891_6 PFAM fructose-bisphosphate aldolase class-I K01623 - 4.1.2.13 0.00000000000000000000000000000000000005663 144.0
HFD2_k127_5609891_7 BON domain - - - 0.0000000000000000000009725 99.0
HFD2_k127_5621666_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.01e-267 874.0
HFD2_k127_5621666_1 - - - - 0.000000000000000000000000000000001157 139.0
HFD2_k127_5621666_2 Protein of unknown function (DUF983) - - - 0.000000000000000000002885 100.0
HFD2_k127_5621666_3 - - - - 0.00000000000000000002159 97.0
HFD2_k127_5635420_0 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000003089 207.0
HFD2_k127_5635420_1 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000005083 205.0
HFD2_k127_5635420_2 d-proline reductase K10794 - 1.21.4.1 0.0000000000000001309 84.0
HFD2_k127_5635420_3 - - - - 0.00000000005829 66.0
HFD2_k127_5669834_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 1.488e-219 695.0
HFD2_k127_5669834_1 PFAM phosphoesterase, RecJ domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006174 331.0
HFD2_k127_5669834_11 Archease protein family (MTH1598/TM1083) - - - 0.00000000000000000001299 99.0
HFD2_k127_5669834_12 - - - - 0.000000000000000004738 91.0
HFD2_k127_5669834_13 Binding-protein-dependent transport system inner membrane component - - - 0.00000000953 60.0
HFD2_k127_5669834_14 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway K03707 - 3.5.99.2 0.0004922 51.0
HFD2_k127_5669834_2 thiolester hydrolase activity K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 291.0
HFD2_k127_5669834_3 YceG-like family K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001499 280.0
HFD2_k127_5669834_4 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.000000000000000000000000000000000000000000000000000000005729 217.0
HFD2_k127_5669834_5 reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000009403 207.0
HFD2_k127_5669834_6 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000003752 203.0
HFD2_k127_5669834_7 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.0000000000000000000000000000000000003255 149.0
HFD2_k127_5669834_8 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000001239 127.0
HFD2_k127_5669834_9 Glycolate oxidase subunit K00104 - 1.1.3.15 0.000000000000000000000001057 119.0
HFD2_k127_5674941_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 394.0
HFD2_k127_5674941_1 - - - - 0.0000000000000000000000000002983 128.0
HFD2_k127_5674941_2 Glycosyl transferase family 2 - - - 0.0000000000000000001418 89.0
HFD2_k127_5691728_0 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000000000000000009774 219.0
HFD2_k127_5691728_1 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.0000000000000000000000000001754 120.0
HFD2_k127_5691728_2 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000001769 118.0
HFD2_k127_5691728_3 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.000000000000001769 77.0
HFD2_k127_569187_0 PFAM ABC transporter related K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007267 331.0
HFD2_k127_569187_1 Mammalian cell entry related domain protein K02067,K06192 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001848 269.0
HFD2_k127_569187_2 Permease MlaE K02066 - - 0.00000000000000000000000000000001616 128.0
HFD2_k127_5695193_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 4.713e-271 858.0
HFD2_k127_5695193_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005042 566.0
HFD2_k127_5695193_2 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 322.0
HFD2_k127_5695193_3 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007136 256.0
HFD2_k127_5695193_4 Peptidase dimerisation domain K13049 - - 0.000000000000000000000000000000000000000000000000000006871 195.0
HFD2_k127_5695193_5 Transcriptional regulator - - - 0.000000000000000000008876 100.0
HFD2_k127_5700488_0 NAD dependent epimerase/dehydratase family K07535 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003368 256.0
HFD2_k127_5700488_1 CoA-substrate-specific enzyme activase - - - 0.0000000000000000000000000000000000000000000000000000000000000002223 229.0
HFD2_k127_5700488_2 ferredoxin oxidoreductase K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000009475 227.0
HFD2_k127_5700488_3 PFAM Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000001548 204.0
HFD2_k127_5700488_4 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.000000000005279 79.0
HFD2_k127_5700488_5 CoA-substrate-specific enzyme activase - - - 0.0000000001827 63.0
HFD2_k127_5700488_6 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.00001787 54.0
HFD2_k127_5710113_0 PFAM Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 354.0
HFD2_k127_5710113_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 355.0
HFD2_k127_5710113_2 Outer membrane lipoprotein-sorting protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 321.0
HFD2_k127_5710113_3 COG4591 ABC-type transport system, involved in lipoprotein release, permease component K02004 - - 0.0000000000000000000000000756 108.0
HFD2_k127_5710113_4 ATP-grasp domain K01905,K22224 - 6.2.1.13 0.000000000000000009392 83.0
HFD2_k127_5714007_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 2.05e-199 647.0
HFD2_k127_5714007_1 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000003327 214.0
HFD2_k127_5714007_2 NMT1-like family - - - 0.00000000000000000000000000239 124.0
HFD2_k127_5714007_3 Major facilitator Superfamily - - - 0.0000000000007272 77.0
HFD2_k127_5716965_0 Cytochrome c K00373,K00405,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.0000000000000000000000000000000000000000000000000000000002176 213.0
HFD2_k127_5716965_1 FmdE, Molybdenum formylmethanofuran dehydrogenase operon K11261 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000454 193.0
HFD2_k127_5716965_2 Molybdopterin-guanine dinucleotide biosynthesis K03753,K13818 - 2.7.7.77 0.0000000000000000000000001713 119.0
HFD2_k127_5716965_3 - - - - 0.000001531 56.0
HFD2_k127_5717240_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009647 417.0
HFD2_k127_5717240_1 Benzoyl-CoA reductase 2-hydroxyglutaryl-CoA dehydratase subunit, BcrC BadD HgdB K04113 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 330.0
HFD2_k127_5717240_2 acetyl-coa acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 308.0
HFD2_k127_5717240_3 BadF/BadG/BcrA/BcrD ATPase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001565 250.0
HFD2_k127_5717240_4 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000005359 221.0
HFD2_k127_5717240_5 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.00000000000000000000000000000001836 134.0
HFD2_k127_5717240_6 Benzoyl-CoA reductase 2-hydroxyglutaryl-CoA dehydratase subunit, BcrC BadD - - - 0.0000000000000000000000000005849 124.0
HFD2_k127_57173_0 Pterin binding enzyme K00548,K15023 - 2.1.1.13,2.1.1.258 0.0 1723.0
HFD2_k127_57173_1 arsR family - - - 0.00000000000000000000000000000000000000000003229 176.0
HFD2_k127_57173_2 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000008849 63.0
HFD2_k127_5721793_0 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 458.0
HFD2_k127_5721793_1 TonB-dependent receptor K02014 - - 0.0000000000000000000000001763 118.0
HFD2_k127_572297_0 Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 1.644e-195 623.0
HFD2_k127_572297_1 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000227 192.0
HFD2_k127_572297_2 Domain of Unknown Function (DUF748) - - - 0.000000000000000000000000000000000000000003574 162.0
HFD2_k127_572297_3 ABC-type nitrate sulfonate bicarbonate transport - - - 0.0000000000001628 81.0
HFD2_k127_5740654_0 Oligopeptidase F K08602 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 522.0
HFD2_k127_5740654_1 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K19244 GO:0000166,GO:0000286,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006522,GO:0006807,GO:0008150,GO:0008152,GO:0009078,GO:0009987,GO:0016491,GO:0016638,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046983,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901605 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000007411 271.0
HFD2_k127_5769167_0 response regulator K07712 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004787 515.0
HFD2_k127_5769167_1 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 461.0
HFD2_k127_5769167_2 Nitrogen fixation master sensor histidine kinase, PAS domain-containing K02668,K07708,K07709 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006445 323.0
HFD2_k127_5769167_3 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788,K14153 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3,2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000003871 178.0
HFD2_k127_5769167_4 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000007828 135.0
HFD2_k127_5769167_5 Protein of unknown function (DUF448) K07742 - - 0.0000000002295 64.0
HFD2_k127_5769167_6 PFAM helicase domain protein - - - 0.00000000461 58.0
HFD2_k127_5769167_7 SMART extracellular solute-binding protein family 3 K02051 - - 0.00000005369 64.0
HFD2_k127_5769167_8 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00002263 52.0
HFD2_k127_581423_0 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001398 229.0
HFD2_k127_581423_1 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000007155 216.0
HFD2_k127_581423_2 RibD C-terminal domain - - - 0.00000000000000002917 83.0
HFD2_k127_581423_3 Gram-negative bacterial TonB protein C-terminal - - - 0.00007705 51.0
HFD2_k127_5815753_0 COG1960 Acyl-CoA dehydrogenases - - - 0.000000000000000000000000000000000000000000000000000000000000000747 234.0
HFD2_k127_5815753_2 PFAM acyl-CoA dehydrogenase domain protein - - - 0.0000000002065 65.0
HFD2_k127_586669_0 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 558.0
HFD2_k127_586669_1 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000004326 218.0
HFD2_k127_586669_2 PFAM histidine triad (HIT) protein K19710 - 2.7.7.53 0.0000000000000000000000000000000000000000000000003595 182.0
HFD2_k127_586669_3 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141 - 0.0000000000000000000000000015 115.0
HFD2_k127_586669_4 signal peptide peptidase SppA, 36K type K04773 - - 0.0000000000000000002608 91.0
HFD2_k127_587219_0 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000003361 227.0
HFD2_k127_587219_1 nucleic acid binding OB-fold tRNA helicase-type K03698 - - 0.0000000000000000000000000000000000000000000000101 177.0
HFD2_k127_587219_2 YGGT family K02221 - - 0.00000000000000000000000000003689 121.0
HFD2_k127_587219_3 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) - - - 0.0000000000000000003604 94.0
HFD2_k127_587219_4 - - - - 0.00000000005829 66.0
HFD2_k127_5886059_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 0.0 1304.0
HFD2_k127_5886059_1 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.0000000000000000000000000000000000000000000000008088 182.0
HFD2_k127_5886059_2 Signal peptidase (SPase) II K03101 - 3.4.23.36 0.00000000000000000000000000000000000001969 149.0
HFD2_k127_5886059_3 Thioredoxin-like - - - 0.00000000000000000000000000000123 129.0
HFD2_k127_5886059_4 Smr domain - - - 0.000001176 56.0
HFD2_k127_5898521_0 Sulfatase K01130 - 3.1.6.1 1.905e-251 779.0
HFD2_k127_5898521_1 MULE transposase domain - - - 0.0000000001558 63.0
HFD2_k127_5909699_0 Aminotransferase class I and II K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 391.0
HFD2_k127_5909699_1 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000007242 214.0
HFD2_k127_5909699_2 YacP-like NYN domain K06962 - - 0.000000000000000000000269 102.0
HFD2_k127_5913673_0 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007653 415.0
HFD2_k127_5913673_1 Sigma-54 interaction domain K02481,K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003717 286.0
HFD2_k127_5913673_2 Domain of unknown function (DUF4388) K12132 - 2.7.11.1 0.00000000002047 74.0
HFD2_k127_5913673_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000003126 70.0
HFD2_k127_5913673_4 gag-polyprotein putative aspartyl protease K06985 - - 0.0000004275 60.0
HFD2_k127_5935673_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 1.299e-230 729.0
HFD2_k127_5935673_1 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 351.0
HFD2_k127_5935673_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000216 181.0
HFD2_k127_5935673_3 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000000000000000000000000000000000000001365 179.0
HFD2_k127_5935673_4 Belongs to the ompA family K03286 - - 0.000000000000000001915 93.0
HFD2_k127_5935673_5 Major facilitator superfamily MFS_1 - - - 0.000000002106 63.0
HFD2_k127_5950643_0 PFAM PrkA AAA K07180 - - 3.497e-242 755.0
HFD2_k127_5950643_1 response regulator - - - 0.000000000000000000000000000000000000002239 169.0
HFD2_k127_5950643_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000001359 66.0
HFD2_k127_5958013_0 Glucose-6-phosphate dehydrogenase, NAD binding domain K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006469 596.0
HFD2_k127_5958013_1 helix_turn_helix, cAMP Regulatory protein K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.0000002538 57.0
HFD2_k127_5958959_0 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006736 458.0
HFD2_k127_5958959_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 451.0
HFD2_k127_5958959_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 321.0
HFD2_k127_5958959_3 PFAM Dihydrodipicolinate synthetase K11946,K11949 - 4.1.2.34 0.0000000000000000000000000000000000000000000000000000000002748 217.0
HFD2_k127_5958959_4 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000004348 177.0
HFD2_k127_5958959_5 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000007522 111.0
HFD2_k127_599832_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004066 289.0
HFD2_k127_599832_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007609 290.0
HFD2_k127_599832_2 PFAM Nickel cobalt transporter, high-affinity - - - 0.00000000000000000000000000000000000000000000000000000000001686 214.0
HFD2_k127_599832_3 FAD metabolic process K00953,K15429 GO:0003674,GO:0003824,GO:0003919,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0042726,GO:0042727,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046443,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0070566,GO:0071704,GO:0071944,GO:0072387,GO:0072388,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.228,2.7.7.2 0.0000000000000000000000000000000000000000000000000000004022 202.0
HFD2_k127_599832_4 MoaE protein K21142 - 2.8.1.12 0.0000000000000000000000000000000000000004237 153.0
HFD2_k127_599832_5 May be involved in the biosynthesis of molybdopterin K03638,K03831 - 2.7.7.75 0.00000002786 55.0
HFD2_k127_6012610_0 Belongs to the UbiD family K03182 - 4.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 571.0
HFD2_k127_6012610_1 COG3842 ABC-type spermidine putrescine transport systems, ATPase components K02010,K02017,K15497 - 3.6.3.29,3.6.3.30,3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 320.0
HFD2_k127_6012610_2 NMT1-like family K02051 - - 0.0001373 49.0
HFD2_k127_601285_0 FMN-dependent dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 350.0
HFD2_k127_601285_1 - - - - 0.0000000000000000006593 89.0
HFD2_k127_6036127_0 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009167 485.0
HFD2_k127_6036127_1 FAD dependent oxidoreductase K13796 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000966 434.0
HFD2_k127_6036127_10 STAS domain K06378 - - 0.00000000002358 67.0
HFD2_k127_6036127_11 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.000003104 59.0
HFD2_k127_6036127_12 Belongs to the UbiD family K03182 - 4.1.1.98 0.00001259 51.0
HFD2_k127_6036127_2 Belongs to the UbiD family K03182 - 4.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 382.0
HFD2_k127_6036127_3 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000000006707 205.0
HFD2_k127_6036127_4 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000000000000000000000000000001387 181.0
HFD2_k127_6036127_5 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000001608 112.0
HFD2_k127_6036127_6 Asp/Glu/Hydantoin racemase K01799 - 5.2.1.1 0.0000000000000000000002836 106.0
HFD2_k127_6036127_7 Catalyzes the conversion of maleate to fumarate K01799,K06033 - 4.1.1.76,5.2.1.1 0.0000000000000000000009503 104.0
HFD2_k127_6036127_8 NMT1-like family - - - 0.00000000000002295 84.0
HFD2_k127_6036127_9 NMT1-like family K02051 - - 0.000000000001514 79.0
HFD2_k127_6077239_0 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 368.0
HFD2_k127_6077239_1 YceI-like domain - - - 0.00000000000000000000000000000000000002257 150.0
HFD2_k127_6077239_2 flavin-nucleotide-binding protein structurally related to pyridoxine 5-phosphate oxidase K07006 - - 0.0000000000002508 78.0
HFD2_k127_6119789_0 peptidyl-lysine modification to peptidyl-hypusine K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 612.0
HFD2_k127_6119789_1 - - - - 0.000000000000000000000000000000000006878 142.0
HFD2_k127_6119789_2 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.00000000000000000000002182 102.0
HFD2_k127_6123085_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 2.427e-258 806.0
HFD2_k127_6123085_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 306.0
HFD2_k127_6123085_2 cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000003839 213.0
HFD2_k127_6123085_3 deacetylase K22278 - 3.5.1.104 0.000000000000000000000000000000000000000001627 168.0
HFD2_k127_6139124_0 PFAM amidohydrolase - - - 2.845e-306 949.0
HFD2_k127_6139124_1 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005201 540.0
HFD2_k127_6139124_2 Hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 426.0
HFD2_k127_6139124_3 Antibiotic biosynthesis monooxygenase K09932 - - 0.000000000000000000000000000000000000000000000000001007 190.0
HFD2_k127_6139124_4 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.0000000000000000000000000000000000000001704 152.0
HFD2_k127_6139124_5 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000008954 128.0
HFD2_k127_6139124_6 light absorption K06893 - - 0.0000000001654 67.0
HFD2_k127_6139182_0 Belongs to the RtcB family K14415 - 6.5.1.3 3.8e-224 703.0
HFD2_k127_6139182_1 PFAM band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004588 323.0
HFD2_k127_6139182_2 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000003833 185.0
HFD2_k127_6139182_3 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.000000000000000000000000006363 112.0
HFD2_k127_6139182_4 Domain of unknown function (DUF2703) - - - 0.00000002662 59.0
HFD2_k127_6139182_5 GYD domain - - - 0.000004196 52.0
HFD2_k127_6141281_0 Predicted membrane protein (DUF2157) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 479.0
HFD2_k127_6141281_1 Dioxygenase K00449 - 1.13.11.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001535 285.0
HFD2_k127_6141281_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001323 276.0
HFD2_k127_6141281_3 - - - - 0.000000000000000000000000000000000001314 144.0
HFD2_k127_6141281_4 ABC-type nitrate sulfonate bicarbonate transport system, permease component K02050 - - 0.00000000000000000000000000000008915 130.0
HFD2_k127_6141281_5 NMT1-like family K02051 - - 0.00002914 55.0
HFD2_k127_6148241_0 Aerotolerance regulator N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000005252 243.0
HFD2_k127_6148241_1 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000955 61.0
HFD2_k127_6151435_0 Fe-S oxidoreductase - - - 2.654e-313 970.0
HFD2_k127_6151435_1 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000000000000000018 137.0
HFD2_k127_6151435_2 Glyceraldehyde-3-phosphate dehydrogenase K00150 - 1.2.1.59 0.000000000000000000000000000000003206 130.0
HFD2_k127_6171580_0 Conserved carboxylase domain K01571 - 4.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 352.0
HFD2_k127_6171580_1 NMT1-like family - - - 0.00000000000000000004458 102.0
HFD2_k127_6171580_2 Belongs to the UbiD family K01612 - 4.1.1.61 0.000003697 53.0
HFD2_k127_6171580_3 Conserved carboxylase domain K01571 - 4.1.1.3 0.0000122 50.0
HFD2_k127_6176680_0 lipopolysaccharide transport K22110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002634 434.0
HFD2_k127_6176680_1 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001093 254.0
HFD2_k127_6176680_2 PFAM S23 ribosomal protein - - - 0.00000000000000000000000000000000000009596 145.0
HFD2_k127_6176680_3 Domain of unknown function (DUF1989) - - - 0.0000000000000000000000000000003872 132.0
HFD2_k127_6176680_4 glutathione-disulfide reductase activity K00383 - 1.8.1.7 0.0000003526 53.0
HFD2_k127_6179058_0 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin K13274,K14645 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007648 347.0
HFD2_k127_6179058_1 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000005397 170.0
HFD2_k127_6179058_2 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000000000000000000004311 170.0
HFD2_k127_6179058_3 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.000000000000000000000002166 104.0
HFD2_k127_6179992_0 Uncharacterised protein family (UPF0182) K09118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007455 505.0
HFD2_k127_6179992_1 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00169,K19070 GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 486.0
HFD2_k127_6179992_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 418.0
HFD2_k127_6179992_3 Pyruvate synthase delta chain (Pyruvic-ferredoxin oxidoreductase delta chain) (PorD-like) K00171 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004834 345.0
HFD2_k127_6179992_4 FCD K05799 - - 0.000000000000000000000000000000000000003601 155.0
HFD2_k127_6179992_5 - - - - 0.0000009454 51.0
HFD2_k127_6182256_0 Multidrug ABC transporter ATP-binding protein K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 458.0
HFD2_k127_6182256_1 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 333.0
HFD2_k127_6182256_2 F420H(2)-dependent quinone reductase - - - 0.000000000001478 73.0
HFD2_k127_6182256_3 F420H(2)-dependent quinone reductase - - - 0.000005945 49.0
HFD2_k127_6196083_0 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000008165 252.0
HFD2_k127_6196083_1 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000008704 194.0
HFD2_k127_6201476_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 596.0
HFD2_k127_6201476_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 364.0
HFD2_k127_6201476_2 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 349.0
HFD2_k127_6201476_3 reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002596 280.0
HFD2_k127_6201476_4 TIGRFAM sugar-phosphate isomerase, RpiB LacA LacB family K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000003577 174.0
HFD2_k127_6201476_5 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000000000000000000000008825 108.0
HFD2_k127_6201476_6 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000001574 103.0
HFD2_k127_6201476_7 Ribosomal L32p protein family K02911 - - 0.0000000000000004412 79.0
HFD2_k127_6201479_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 3.154e-268 844.0
HFD2_k127_6201479_1 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 524.0
HFD2_k127_6201479_2 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000003016 195.0
HFD2_k127_6201479_3 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272,K21345 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000002192 179.0
HFD2_k127_6201479_4 - - - - 0.000000000000000000000000827 105.0
HFD2_k127_6201479_5 CAAX protease self-immunity K07052 - - 0.0000000000000000000002445 103.0
HFD2_k127_6201479_6 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000004582 85.0
HFD2_k127_62058_0 Threonine dehydratase K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008155 437.0
HFD2_k127_62058_1 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007142 314.0
HFD2_k127_62058_2 Nitroreductase family - - - 0.000002725 49.0
HFD2_k127_6208775_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000009711 214.0
HFD2_k127_6208775_1 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000000000000003305 138.0
HFD2_k127_6208775_2 Amidohydrolase K07045 - - 0.00000000000000000000971 95.0
HFD2_k127_6213906_0 ABC transporter K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 292.0
HFD2_k127_6213906_1 tRNA methyltransferase complex GCD14 subunit N-term K07442 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0031515,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.219,2.1.1.220 0.00000000000000000000000000000000000000000000000000000000000000000000000000000176 271.0
HFD2_k127_6213906_2 PFAM Nucleotidyl transferase K00971,K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000009456 250.0
HFD2_k127_6213906_3 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000008649 195.0
HFD2_k127_6213906_4 ABC-type nitrate sulfonate bicarbonate transport system, permease component K02050 - - 0.000000000000000000000000000000000000000000003653 182.0
HFD2_k127_6213926_0 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000779 470.0
HFD2_k127_6213926_1 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008963 345.0
HFD2_k127_6213926_2 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000002838 240.0
HFD2_k127_6213926_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000008217 177.0
HFD2_k127_6216663_0 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000005222 174.0
HFD2_k127_6216663_1 ABC transporter substrate binding protein K01989 - - 0.000000000000000001972 93.0
HFD2_k127_6216663_2 NMT1-like family K02051 - - 0.000000000002939 78.0
HFD2_k127_6216663_3 COG0006 Xaa-Pro aminopeptidase - - - 0.00001502 48.0
HFD2_k127_6225123_0 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005174 301.0
HFD2_k127_6225123_1 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000002942 212.0
HFD2_k127_6227333_0 Belongs to the UbiD family K03182 - 4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004647 463.0
HFD2_k127_6227333_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 GO:0001510,GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0003824,GO:0004808,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016782,GO:0016783,GO:0030488,GO:0032259,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 318.0
HFD2_k127_6227333_2 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000005722 233.0
HFD2_k127_6227333_3 Peptidase family S51 K01256 - 3.4.11.2 0.00000000000000000000000000000000000000000000000000000000000006291 217.0
HFD2_k127_6227333_4 NMT1-like family K02051 - - 0.0000000000000000001881 100.0
HFD2_k127_6227333_5 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000001407 53.0
HFD2_k127_6235080_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 604.0
HFD2_k127_6235080_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000002141 255.0
HFD2_k127_6235080_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000006245 239.0
HFD2_k127_6235080_3 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000001424 186.0
HFD2_k127_6238545_0 Belongs to the RtcB family K14415 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 397.0
HFD2_k127_6238545_1 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000002778 88.0
HFD2_k127_624076_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 5.548e-252 803.0
HFD2_k127_624076_1 4Fe-4S dicluster domain K17048,K17051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 439.0
HFD2_k127_624076_2 Molydopterin dinucleotide binding domain K10700,K17050 - 1.17.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 298.0
HFD2_k127_624076_3 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007423 286.0
HFD2_k127_624076_4 Nitrate reductase delta subunit - - - 0.00000000000000000142 94.0
HFD2_k127_6242275_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 340.0
HFD2_k127_6242275_1 Crp-like helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 327.0
HFD2_k127_6242275_2 CHASE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009976 331.0
HFD2_k127_6242275_3 Two component transcriptional regulator, LuxR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005393 248.0
HFD2_k127_6242275_4 CsbD-like - - - 0.000000000000000000000001212 106.0
HFD2_k127_6242275_5 response regulator K02282,K07705 - - 0.0000000000000000000001419 102.0
HFD2_k127_6245628_0 PA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 373.0
HFD2_k127_6245628_1 phosphatidylcholine synthase activity K01004,K17103 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050520,GO:0071704,GO:0090407,GO:1901576 2.7.8.24,2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000006892 237.0
HFD2_k127_6245628_2 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 0.000000000000000000000000000000000000000000000000000257 201.0
HFD2_k127_6245628_3 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000003031 135.0
HFD2_k127_6246213_0 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000001024 119.0
HFD2_k127_6246213_1 beta-lactamase domain protein K05555 - - 0.00000000000000000000001696 107.0
HFD2_k127_6262621_0 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate K01612 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044464 4.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 500.0
HFD2_k127_6262621_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001579 244.0
HFD2_k127_6262621_2 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000007345 202.0
HFD2_k127_6262621_3 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000004886 200.0
HFD2_k127_6262621_4 carbon monoxide dehydrogenase K09386 - - 0.0000000002408 67.0
HFD2_k127_6263971_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K00087,K03520 - 1.17.1.4,1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 518.0
HFD2_k127_6263971_1 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM-like protein K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000003777 225.0
HFD2_k127_6263971_2 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000006286 200.0
HFD2_k127_6263971_3 Selenium-dependent molybdenum hydroxylase system protein, YqeB family K07402 - - 0.00000000000000000000000000000000000000000000000000000028 201.0
HFD2_k127_6263971_4 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000002787 108.0
HFD2_k127_6263971_5 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.000000000000000512 79.0
HFD2_k127_6278655_0 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis - - - 2.43e-288 893.0
HFD2_k127_6278655_1 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000000002203 181.0
HFD2_k127_6278655_2 Class ii aldolase K01628 - 4.1.2.17 0.000000000000000000000000000003843 129.0
HFD2_k127_6278655_3 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000001202 121.0
HFD2_k127_6278655_4 glutamine synthetase K01915 - 6.3.1.2 0.000000000000001448 76.0
HFD2_k127_629487_0 Protein of unknown function (DUF3500) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 429.0
HFD2_k127_629487_1 MmgE/PrpD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003488 255.0
HFD2_k127_629487_2 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000005922 216.0
HFD2_k127_629487_3 Metallopeptidase family M24 - - - 0.0000000000000000000000000000000000000000000000000000002064 209.0
HFD2_k127_629487_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.00000000000000000000000000000000000004874 146.0
HFD2_k127_629487_5 thiamine-containing compound biosynthetic process K02051 - - 0.00000000003888 74.0
HFD2_k127_629487_6 thiamine-containing compound biosynthetic process K02051 - - 0.0000000002202 72.0
HFD2_k127_6298739_0 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005144 415.0
HFD2_k127_6298739_1 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000006896 254.0
HFD2_k127_6298739_2 major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000001951 210.0
HFD2_k127_6298739_3 thiamine-containing compound biosynthetic process K02051 - - 0.00000000004976 74.0
HFD2_k127_6311688_0 Sigma-54 interaction domain K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 416.0
HFD2_k127_6311688_1 Mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000000001511 192.0
HFD2_k127_6311688_2 GAF domain K07315 - 3.1.3.3 0.000000000000000000000000000000000000003147 163.0
HFD2_k127_6311688_3 Response regulator receiver domain - - - 0.000000000001954 72.0
HFD2_k127_6311688_4 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.0000000002827 70.0
HFD2_k127_6311688_5 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.0000002889 53.0
HFD2_k127_6311688_6 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.00003002 48.0
HFD2_k127_6311688_7 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.0003504 44.0
HFD2_k127_6320017_0 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005868 542.0
HFD2_k127_6320017_1 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit K00162,K11381 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006104 364.0
HFD2_k127_6320017_2 PFAM dehydrogenase, E1 component K21416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 307.0
HFD2_k127_6329003_0 Sigma-54 interaction domain K15836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004766 553.0
HFD2_k127_6329003_1 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000009844 122.0
HFD2_k127_6329003_2 Putative zinc-finger - - - 0.000004726 55.0
HFD2_k127_634223_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000473 282.0
HFD2_k127_634223_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006089 267.0
HFD2_k127_634223_2 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000000005685 154.0
HFD2_k127_634223_3 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.000000000000000000000002114 106.0
HFD2_k127_6343551_0 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000001909 224.0
HFD2_k127_6343551_1 Acyl-transferase K00655,K01897 - 2.3.1.51,6.2.1.3 0.0000000000000000000000000000000000000000000000000003438 193.0
HFD2_k127_6343551_2 cdp-diacylglycerol--glycerol-3-phosphate - - - 0.000000000000000000000000005306 120.0
HFD2_k127_6343551_3 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source - - - 0.000000000000000000002303 96.0
HFD2_k127_6347629_0 AAA domain (dynein-related subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 359.0
HFD2_k127_6347629_1 Type II secretion system K02455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009714 347.0
HFD2_k127_6347629_10 Domain of unknown function DUF120 K07732 - 2.7.1.161 0.00000000000000306 80.0
HFD2_k127_6347629_11 general secretion pathway protein K02457 - - 0.00000000000002581 82.0
HFD2_k127_6347629_12 General secretion pathway protein K02458 - - 0.0000000003357 66.0
HFD2_k127_6347629_13 pilus assembly protein PilW K02459 - - 0.0000000003905 70.0
HFD2_k127_6347629_14 General Secretion Pathway protein K02462 - - 0.00008475 53.0
HFD2_k127_6347629_2 VWA domain containing CoxE-like protein K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 299.0
HFD2_k127_6347629_3 Bacterial type II and III secretion system protein K02453 - - 0.00000000000000000000000000000000000000000000000000001285 210.0
HFD2_k127_6347629_4 PFAM type II secretion system protein G K02456 - - 0.000000000000000000000000000000000000000000000000008372 185.0
HFD2_k127_6347629_5 XdhC Rossmann domain K07402 - - 0.000000000000000000000000000000000000000000001317 175.0
HFD2_k127_6347629_6 Type II secretion system (T2SS), protein K K02460 - - 0.00000000000000000000000000000000000000000001407 177.0
HFD2_k127_6347629_7 Type II and III secretion system protein K02453 - - 0.0000000000000000000000000000000006258 146.0
HFD2_k127_6347629_8 Fimbrial assembly protein (PilN) K02461 - - 0.000000000000000000000000000000007472 146.0
HFD2_k127_6347629_9 molybdopterin cofactor binding K07402 - - 0.0000000000000000000000000000012 125.0
HFD2_k127_6351661_0 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 484.0
HFD2_k127_6351661_1 Domain of unknown function (DUF427) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 300.0
HFD2_k127_6351661_2 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K02439,K07390 GO:0003674,GO:0003824,GO:0004792,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016740,GO:0016782,GO:0016783,GO:0044424,GO:0044464 2.8.1.1 0.000000000000000000000000000000004431 130.0
HFD2_k127_6366659_0 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000001311 242.0
HFD2_k127_6377700_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 426.0
HFD2_k127_6377700_1 40-residue yvtn family beta-propeller repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001629 252.0
HFD2_k127_6377700_2 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000008844 225.0
HFD2_k127_6377700_3 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000427 113.0
HFD2_k127_6382964_0 ATP ADP translocase K03301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 549.0
HFD2_k127_6382964_1 DegT/DnrJ/EryC1/StrS aminotransferase family K12452,K13017 - 1.17.1.1,2.6.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008676 499.0
HFD2_k127_6382964_2 COG0656 Aldo keto reductases, related to diketogulonate reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005399 385.0
HFD2_k127_6382964_3 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000004045 244.0
HFD2_k127_6382964_4 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000009217 229.0
HFD2_k127_6382964_5 Sulfotransferase family - - - 0.0000000001278 65.0
HFD2_k127_6387604_0 ABC-type Fe3 transport system, periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007985 266.0
HFD2_k127_6387604_1 NMT1-like family K02051 - - 0.0000000000006173 79.0
HFD2_k127_6387604_2 Lipocalin-like domain - - - 0.0000000000007408 75.0
HFD2_k127_6387604_3 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.0000000002393 72.0
HFD2_k127_6405602_0 PD-(D/E)XK nuclease superfamily - - - 1.064e-244 796.0
HFD2_k127_6405602_2 Phosphoglycerate mutase family K01834 - 5.4.2.11 0.000000000000000000000000000000000005176 144.0
HFD2_k127_6405602_3 DNA replication proofreading K02336,K06877,K07501 - 2.7.7.7 0.00000000000000000000000000005574 124.0
HFD2_k127_6405602_4 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000007044 86.0
HFD2_k127_6405602_5 DNA replication proofreading K02336,K06877,K07501 - 2.7.7.7 0.000000000011 67.0
HFD2_k127_6406055_0 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000002365 134.0
HFD2_k127_6406055_1 PFAM Alpha beta hydrolase of - - - 0.00003237 53.0
HFD2_k127_6417193_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1012.0
HFD2_k127_6417193_1 PFAM glycoside hydrolase family 77 K00705 - 2.4.1.25 4.317e-202 650.0
HFD2_k127_6417193_2 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009365 349.0
HFD2_k127_6425119_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 1.517e-212 674.0
HFD2_k127_6425119_1 TIGRFAM TRAP transporter solute receptor, TAXI family K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008508 327.0
HFD2_k127_6425119_2 Domain of unknown function (DUF1850) - - - 0.00008383 51.0
HFD2_k127_6433860_0 Belongs to the thiolase family K00626,K07508 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 492.0
HFD2_k127_6433860_1 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K00162 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 444.0
HFD2_k127_6433860_10 PFAM Phage derived protein Gp49-like (DUF891) - - - 0.0000000000000000002748 89.0
HFD2_k127_6433860_11 2Fe-2S -binding domain - - - 0.00000000248 62.0
HFD2_k127_6433860_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 431.0
HFD2_k127_6433860_3 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 418.0
HFD2_k127_6433860_4 e3 binding domain K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 363.0
HFD2_k127_6433860_5 Peptidase family M28 K01258 - 3.4.11.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 358.0
HFD2_k127_6433860_6 PFAM 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000001613 243.0
HFD2_k127_6433860_7 Divergent AAA domain protein K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000001805 230.0
HFD2_k127_6433860_8 O-methyltransferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000007469 205.0
HFD2_k127_6433860_9 Helix-turn-helix domain - - - 0.000000000000000000000249 100.0
HFD2_k127_6437387_0 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 525.0
HFD2_k127_6437387_1 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005231 297.0
HFD2_k127_6444672_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.00000000000000000000000000000000000000000000000000005511 191.0
HFD2_k127_6444672_1 aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K03518,K20446 - 1.17.1.5,1.2.5.3 0.00000000000000000000000000000000000000000000000005543 183.0
HFD2_k127_645368_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005821 412.0
HFD2_k127_645368_1 deaminated base DNA N-glycosylase activity K21929 GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 297.0
HFD2_k127_645368_2 FAD linked oxidase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000002454 212.0
HFD2_k127_645368_3 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000001016 72.0
HFD2_k127_6454852_0 alcohol dehydrogenase K00001,K00008 - 1.1.1.1,1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001857 289.0
HFD2_k127_6468876_0 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000005975 234.0
HFD2_k127_6468876_1 associated with various cellular activities K03924 - - 0.000000000000000000000000000000005328 129.0
HFD2_k127_6468876_2 Q COG1233 Phytoene dehydrogenase and related proteins - - - 0.00000000129 59.0
HFD2_k127_6476942_0 HlyD family secretion protein K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003814 263.0
HFD2_k127_6476942_1 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000339 256.0
HFD2_k127_6476942_2 PFAM MltA domain protein K08304 - - 0.000000000000000000000000000000000000000000000000000000000000000000055 237.0
HFD2_k127_6476942_3 ABC transporter K01990 - - 0.0000000000000000000000000000000000000001068 158.0
HFD2_k127_648919_0 4-phosphoerythronate dehydrogenase activity K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 363.0
HFD2_k127_648919_1 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000009809 194.0
HFD2_k127_6490813_0 Sigma-54 interaction domain K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 460.0
HFD2_k127_6490813_1 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002729 284.0
HFD2_k127_6490813_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004381 268.0
HFD2_k127_6490813_3 Acylphosphatase K01512 - 3.6.1.7 0.0000000000000000000000000001251 117.0
HFD2_k127_6490813_4 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.0001268 44.0
HFD2_k127_6499603_0 NMT1-like family - - - 0.0000000000000000000000000009255 122.0
HFD2_k127_6499603_1 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000004696 91.0
HFD2_k127_6500215_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00018,K00058,K03778 - 1.1.1.28,1.1.1.29,1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000005948 153.0
HFD2_k127_6500215_1 Alpha beta hydrolase - - - 0.0000000000000000000000004269 117.0
HFD2_k127_6500215_2 Carboxymuconolactone decarboxylase family - - - 0.000000001974 59.0
HFD2_k127_6500215_3 cellulose binding - - - 0.000000006356 57.0
HFD2_k127_6513975_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 401.0
HFD2_k127_6513975_1 PFAM asparagine synthase K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008496 303.0
HFD2_k127_6513975_2 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000003865 248.0
HFD2_k127_6513975_3 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.000000000000000000000000000000000000000000000000000000168 204.0
HFD2_k127_6513975_4 Transcriptional regulator, CarD family K07736 - - 0.000000000000000000000000000000000000000000000000000006651 193.0
HFD2_k127_6513975_5 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000646 154.0
HFD2_k127_6513975_6 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000000000000000001363 138.0
HFD2_k127_6513975_7 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.000000000000000000000000000001015 128.0
HFD2_k127_6513975_8 Domain of unknown function (DUF1844) - - - 0.00000000000000000000000000208 117.0
HFD2_k127_6513975_9 Belongs to the 'phage' integrase family - - - 0.00008328 46.0
HFD2_k127_6549116_0 Aldehyde dehydrogenase family K00131 - 1.2.1.9 7.385e-222 696.0
HFD2_k127_6549116_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 317.0
HFD2_k127_6549116_2 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 307.0
HFD2_k127_6549116_3 nucleic acid binding K03698 - - 0.0000000000000000000000000000000000000000000000000000368 191.0
HFD2_k127_6549116_4 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000001691 196.0
HFD2_k127_6549116_5 Transposase - - - 0.00000000005759 69.0
HFD2_k127_6563539_0 ornithine cyclodeaminase K01750 - 4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 357.0
HFD2_k127_6563539_1 acetyl-coa acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 331.0
HFD2_k127_6563539_2 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.0000000000000000000000000000000001175 137.0
HFD2_k127_6590230_0 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 424.0
HFD2_k127_6590230_1 Transposase zinc-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006066 394.0
HFD2_k127_6590230_10 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000003258 125.0
HFD2_k127_6590230_11 Preprotein translocase SecG subunit K03075 - - 0.00000000000000000009346 93.0
HFD2_k127_6590230_12 Response regulator, receiver K11443 - - 0.000000000000000001281 87.0
HFD2_k127_6590230_13 TonB C terminal - - - 0.0001232 53.0
HFD2_k127_6590230_2 TolB amino-terminal domain K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 362.0
HFD2_k127_6590230_3 TIGRFAM riboflavin biosynthesis protein RibF K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000003249 273.0
HFD2_k127_6590230_4 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000006441 245.0
HFD2_k127_6590230_5 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000314 244.0
HFD2_k127_6590230_6 MotA/TolQ/ExbB proton channel family K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000002336 242.0
HFD2_k127_6590230_7 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000002708 168.0
HFD2_k127_6590230_8 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.00000000000000000000000000000000000299 142.0
HFD2_k127_6590230_9 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000006399 139.0
HFD2_k127_6653385_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 1.728e-243 771.0
HFD2_k127_6653385_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000001337 208.0
HFD2_k127_6653385_3 phosphinothricin N-acetyltransferase activity K03823,K18816 - 2.3.1.183,2.3.1.82 0.00000000000204 76.0
HFD2_k127_6653385_4 Cupin domain - - - 0.00000000005728 68.0
HFD2_k127_6673003_0 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000001692 218.0
HFD2_k127_6673003_1 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000003327 179.0
HFD2_k127_6689586_0 DDE superfamily endonuclease K07481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 439.0
HFD2_k127_6720516_0 Penicillin amidase K01434 - 3.5.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008392 433.0
HFD2_k127_6720516_1 Glutathione S-transferase K00799 - 2.5.1.18 0.0001065 48.0
HFD2_k127_6722707_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006556 447.0
HFD2_k127_6722707_1 proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000009176 259.0
HFD2_k127_6722707_2 dienelactone hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000006225 235.0
HFD2_k127_6722707_3 alkylbase DNA N-glycosylase activity K03652 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000004125 203.0
HFD2_k127_6722707_4 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000002531 157.0
HFD2_k127_6722707_5 - - - - 0.000000000000000000007544 97.0
HFD2_k127_6722707_6 Phosphodiester glycosidase - - - 0.00001184 56.0
HFD2_k127_6722707_7 F420H(2)-dependent quinone reductase - GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0030312,GO:0031406,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070967,GO:0071944,GO:0097159,GO:0097367,GO:1901363 - 0.0000123 52.0
HFD2_k127_6740658_0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain K00261,K00262 - 1.4.1.3,1.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 493.0
HFD2_k127_6740658_1 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00169,K19070 GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 463.0
HFD2_k127_6740658_2 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007718 392.0
HFD2_k127_6740658_3 Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002635 270.0
HFD2_k127_6740658_4 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000001545 205.0
HFD2_k127_6740658_5 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000000000002421 163.0
HFD2_k127_6740658_6 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000004662 148.0
HFD2_k127_6740658_7 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000001782 153.0
HFD2_k127_6740658_8 - - - - 0.0000000000000000000000000005187 126.0
HFD2_k127_6740658_9 Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000001485 105.0
HFD2_k127_67532_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006252 378.0
HFD2_k127_67532_1 2-methylcitrate dehydratase activity K01720 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019679,GO:0019752,GO:0030312,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046459,GO:0047547,GO:0050896,GO:0071704,GO:0071944,GO:0072329,GO:1901575 4.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 357.0
HFD2_k127_67532_2 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001104 267.0
HFD2_k127_67532_3 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000013 109.0
HFD2_k127_67532_4 Transcriptional regulator - - - 0.00000000000000000002763 95.0
HFD2_k127_67532_5 carboxylic ester hydrolase activity K05714 - 3.7.1.14 0.00000000000005213 81.0
HFD2_k127_67532_6 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0000000904 54.0
HFD2_k127_6757074_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2.458e-291 908.0
HFD2_k127_6757074_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 6.821e-198 623.0
HFD2_k127_6757074_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 307.0
HFD2_k127_6765223_0 DNA polymerase X family K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009653 580.0
HFD2_k127_6765223_1 SEC-C Motif Domain Protein - - - 0.000000000000007149 81.0
HFD2_k127_6771636_0 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 411.0
HFD2_k127_6771636_1 Belongs to the GST superfamily K11209 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004043 294.0
HFD2_k127_6771636_2 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000448 226.0
HFD2_k127_6771636_3 Bacterial extracellular solute-binding protein K02012 - - 0.00004781 50.0
HFD2_k127_6794923_0 Tripartite tricarboxylate transporter TctA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 441.0
HFD2_k127_6794923_1 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000003041 256.0
HFD2_k127_6794923_2 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000006869 205.0
HFD2_k127_6794923_3 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000003505 201.0
HFD2_k127_6794923_4 Amidohydrolase K03392 - 4.1.1.45 0.00000000000000000000000000000000000000000000000000004747 199.0
HFD2_k127_6794923_5 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000001367 198.0
HFD2_k127_6794923_6 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000003361 191.0
HFD2_k127_6794923_7 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000551 186.0
HFD2_k127_6794923_8 Thiamine pyrophosphate enzyme, central domain K01652 GO:0000287,GO:0003674,GO:0003824,GO:0003984,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0019842,GO:0030976,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901681 2.2.1.6 0.00000000000000000000000000000000000000000003283 171.0
HFD2_k127_6800516_0 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.000000000000000000000000000000000000000000000000306 190.0
HFD2_k127_6800516_1 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000009318 182.0
HFD2_k127_6800516_2 4Fe-4S binding domain - - - 0.00000000000000000000000000000004243 128.0
HFD2_k127_6843675_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008616 396.0
HFD2_k127_6843675_1 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000512 250.0
HFD2_k127_6843675_2 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000004762 138.0
HFD2_k127_6843675_3 S23 ribosomal protein - - - 0.0000000000000000000000000000000003881 134.0
HFD2_k127_6843675_4 ABC transporter K01989 - - 0.00000000000000000000009838 107.0
HFD2_k127_6843675_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000003721 57.0
HFD2_k127_6843749_0 Ion transport 2 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 474.0
HFD2_k127_6843749_1 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007444 421.0
HFD2_k127_6843749_2 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 377.0
HFD2_k127_6843749_3 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003426 282.0
HFD2_k127_6843749_4 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000000000000000006642 141.0
HFD2_k127_6843749_5 Catalyzes the reduction of tatronate semialdehyde to D- glycerate K00020,K00042 GO:0003674,GO:0003824,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0008679,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0019392,GO:0019394,GO:0019577,GO:0019579,GO:0019580,GO:0019752,GO:0042737,GO:0042836,GO:0042838,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046392,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.1.1.31,1.1.1.60 0.000000000000000000000000000001541 131.0
HFD2_k127_6843749_6 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source - - - 0.00000000000000000000000000002926 121.0
HFD2_k127_6843749_7 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.000000000000000000006175 105.0
HFD2_k127_6843749_8 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.000000000000001824 88.0
HFD2_k127_6873661_0 Nadph-dependent fmn reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007914 351.0
HFD2_k127_6873661_1 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000001352 119.0
HFD2_k127_6873661_2 PFAM Glyoxalase bleomycin resistance protein dioxygenase K07104 - 1.13.11.2 0.0000002358 59.0
HFD2_k127_6880666_0 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 309.0
HFD2_k127_6880666_1 Transferase hexapeptide repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002667 244.0
HFD2_k127_6880666_2 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000008068 108.0
HFD2_k127_6880666_3 Transferase hexapeptide repeat containing protein - - - 0.00000000129 59.0
HFD2_k127_6912775_0 Binding-protein-dependent transport system inner membrane component K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 424.0
HFD2_k127_6912775_1 Ornithine cyclodeaminase K01750 - 4.3.1.12 0.00000000000000000000000000000000000000000000000000000000001183 214.0
HFD2_k127_6912775_2 Isochorismatase hydrolase - - - 0.000000000000000000000000000000000000000000000000000000004129 207.0
HFD2_k127_6914522_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 8.282e-293 938.0
HFD2_k127_6914522_1 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 311.0
HFD2_k127_6951886_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005984 534.0
HFD2_k127_6951886_1 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006216 338.0
HFD2_k127_6951886_2 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.000000000000000000000000005582 110.0
HFD2_k127_6976494_0 Pfam SNARE associated Golgi protein - - - 7.314e-221 705.0
HFD2_k127_6976494_1 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 331.0
HFD2_k127_6976494_2 Belongs to the UPF0337 (CsbD) family - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000008919 104.0
HFD2_k127_6976494_3 Protein of unknown function (DUF3309) - - - 0.00000000000000000003274 90.0
HFD2_k127_6983566_0 Belongs to the ClpA ClpB family K03694 - - 4.473e-302 943.0
HFD2_k127_6983566_1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002467 589.0
HFD2_k127_6983566_2 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004864 410.0
HFD2_k127_6983566_3 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000000000000000000000004856 130.0
HFD2_k127_6983566_4 signal transduction histidine kinase - - - 0.0000000000000000004575 98.0
HFD2_k127_7008068_0 molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007171 337.0
HFD2_k127_7008068_1 Isochorismatase family K09020 - 3.5.1.110 0.00000000000000000000000000000000000000000000000000001964 196.0
HFD2_k127_701198_0 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002292 257.0
HFD2_k127_701198_1 permease - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000414 233.0
HFD2_k127_701198_2 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000003201 188.0
HFD2_k127_701198_3 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000004528 184.0
HFD2_k127_7015591_0 COG3221 ABC-type phosphate phosphonate transport system, periplasmic component K02044 - - 0.000000000000000000000000000000000000000000002831 176.0
HFD2_k127_7015591_1 NUDIX hydrolase - - - 0.00000000000000000000009738 108.0
HFD2_k127_7015591_2 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000003222 91.0
HFD2_k127_7015591_3 Transport and Golgi organisation 2 - - - 0.000007137 53.0
HFD2_k127_7017720_0 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 307.0
HFD2_k127_7017720_1 Acetolactate synthase, large subunit K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000002295 228.0
HFD2_k127_7017720_2 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000002545 212.0
HFD2_k127_7017720_3 Urate oxidase N-terminal - - - 0.00000000000000000000000000000003401 135.0
HFD2_k127_7023301_0 - - - - 0.000000000000000000000000000000000000000000000000003164 198.0
HFD2_k127_7024621_0 Oxidoreductase family, C-terminal alpha beta domain K00118,K13020 - 1.1.1.335,1.1.99.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 445.0
HFD2_k127_7024621_1 protein involved in outer membrane biogenesis K07290 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0032386,GO:0032879,GO:0032880,GO:0033157,GO:0044464,GO:0050789,GO:0051049,GO:0051223,GO:0060341,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:0090313,GO:1903533,GO:1903827,GO:1905475 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 411.0
HFD2_k127_7024621_2 Predicted membrane protein (DUF2231) - - - 0.000000000000000000000000000000000000008186 150.0
HFD2_k127_7024621_3 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000001099 131.0
HFD2_k127_7024621_4 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide - - - 0.0001485 45.0
HFD2_k127_7024621_5 Metallo-beta-lactamase superfamily - - - 0.0002224 46.0
HFD2_k127_7036632_0 PFAM permease YjgP YjgQ family protein K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000746 237.0
HFD2_k127_7036632_1 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000001247 215.0
HFD2_k127_7036632_2 Predicted permease YjgP/YjgQ family K11720 - - 0.000000000000000000000000000000000000000000000000000198 203.0
HFD2_k127_7036632_3 Ribosomal protein L13 K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000001241 186.0
HFD2_k127_7036632_4 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000003086 168.0
HFD2_k127_7036632_5 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000002412 96.0
HFD2_k127_7042793_0 ornithine cyclodeaminase K01750 - 4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003077 344.0
HFD2_k127_7042793_1 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000007483 222.0
HFD2_k127_7042793_2 peptidase - - - 0.000000000000000000000000000000000000000000000000000381 199.0
HFD2_k127_7042793_3 Peptidase C26 K07010 - - 0.000000000000000000000008034 104.0
HFD2_k127_7048884_0 benzoyl-CoA reductase K04113 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 305.0
HFD2_k127_7048884_1 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000000000000003488 121.0
HFD2_k127_7048884_2 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.000000000000000000000000001491 116.0
HFD2_k127_7053409_0 Belongs to the ompA family - - - 0.00000000000000000000004209 110.0
HFD2_k127_7053409_1 antibiotic catabolic process K18235 - - 0.000000000000251 77.0
HFD2_k127_7054323_0 Evidence 5 No homology to any previously reported sequences - - - 0.000000000000000000000000000000000000000000000000000000000009829 223.0
HFD2_k127_7062689_0 FAD binding domain K00480 - 1.14.13.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 547.0
HFD2_k127_7062689_1 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.0000000000000000009136 91.0
HFD2_k127_7074019_0 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 360.0
HFD2_k127_7074019_1 PFAM thiamine pyrophosphate enzyme-like TPP-binding thiamine pyrophosphate - - - 0.000000004873 57.0
HFD2_k127_7076863_0 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001904 278.0
HFD2_k127_7076863_1 SNARE associated Golgi protein K03975,K19302 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003942 272.0
HFD2_k127_7076863_2 ABC-type nitrate sulfonate bicarbonate transport system, permease component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002431 244.0
HFD2_k127_7076863_3 PFAM glycosyl transferase family 39 - - - 0.000000000000000000000000000000000000000000000000000000000004516 231.0
HFD2_k127_7076863_4 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000001061 189.0
HFD2_k127_7076863_5 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000003165 87.0
HFD2_k127_7076863_6 - - - - 0.0001792 48.0
HFD2_k127_7081846_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 6.439e-308 957.0
HFD2_k127_7081846_1 COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming) K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 451.0
HFD2_k127_7081846_2 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.17.4.1 0.0000000000000000000000000005205 117.0
HFD2_k127_7081846_3 Universal stress protein K06149 - - 0.0000000000000000002788 94.0
HFD2_k127_7081846_4 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.0000000000000000004306 91.0
HFD2_k127_7094021_0 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate and vanillate K01612,K16874 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044464 4.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000095 366.0
HFD2_k127_7094021_1 Belongs to the UbiD family K16874 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006118 335.0
HFD2_k127_7094021_10 Rhodanese Homology Domain - - - 0.0000000000000000000000000000002377 127.0
HFD2_k127_7094021_11 NMT1/THI5 like K02051 - - 0.000000000000000000000007682 113.0
HFD2_k127_7094021_12 Domain of unknown function (DUF1989) K09967 - - 0.000000000000000000002656 102.0
HFD2_k127_7094021_13 NMT1-like family K02051 - - 0.0000000000000000147 94.0
HFD2_k127_7094021_14 NMT1-like family - - - 0.000000000002118 79.0
HFD2_k127_7094021_2 ABC transporter K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 310.0
HFD2_k127_7094021_3 Metallo-beta-lactamase superfamily K01069 GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006090,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019184,GO:0019752,GO:0031974,GO:0032787,GO:0034641,GO:0042398,GO:0043043,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0051186,GO:0051188,GO:0070013,GO:0071704,GO:1901564,GO:1901566,GO:1901576 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009599 282.0
HFD2_k127_7094021_4 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001479 260.0
HFD2_k127_7094021_5 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001646 259.0
HFD2_k127_7094021_6 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000001518 207.0
HFD2_k127_7094021_7 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.00000000000000000000000000000000000000000000000000002119 197.0
HFD2_k127_7094021_8 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.000000000000000000000000000000000000000000000004638 184.0
HFD2_k127_7094021_9 PFAM molybdopterin dehydrogenase, FAD-binding K03519,K11178 - 1.17.1.4,1.2.5.3 0.000000000000000000000000000000000000000001439 162.0
HFD2_k127_7094177_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K01848 - 5.4.99.2 3.389e-209 671.0
HFD2_k127_7094177_1 Dehydrogenase K00248,K11410,K18244 GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0004085,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009605,GO:0009719,GO:0009725,GO:0009987,GO:0009991,GO:0010033,GO:0014070,GO:0016020,GO:0016042,GO:0016043,GO:0016054,GO:0016491,GO:0016627,GO:0017076,GO:0019395,GO:0019605,GO:0019626,GO:0019752,GO:0022607,GO:0030258,GO:0030554,GO:0031090,GO:0031667,GO:0031960,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033539,GO:0033993,GO:0034440,GO:0036094,GO:0042221,GO:0042594,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046359,GO:0046395,GO:0046459,GO:0048037,GO:0048545,GO:0050660,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051384,GO:0052890,GO:0055114,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901567,GO:1901575,GO:1901681 1.3.8.1,1.3.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009415 449.0
HFD2_k127_7094177_2 acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 437.0
HFD2_k127_7094177_3 LAO AO transport system ATPase K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000659 271.0
HFD2_k127_7094177_4 B12 binding domain K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000004084 171.0
HFD2_k127_7094177_5 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 0.000000000000000000000000000000000007164 142.0
HFD2_k127_7096216_0 membrane protein involved in D-alanine K19294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 499.0
HFD2_k127_7098187_0 system Galactitol-specific IIC component K02775 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007475 474.0
HFD2_k127_7098187_1 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000001795 217.0
HFD2_k127_7098187_2 DeoR C terminal sensor domain K02081,K02444,K03436 - - 0.0000000000000000000000000000000000000000000000000000007894 201.0
HFD2_k127_7098187_3 methyltransferase activity - - - 0.0000000000000000000000000189 111.0
HFD2_k127_7098187_4 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000001466 53.0
HFD2_k127_7112588_0 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 592.0
HFD2_k127_7112588_1 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004816 379.0
HFD2_k127_7114908_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.000000000000000000000000000000000000000000000000000001802 194.0
HFD2_k127_7114908_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585,K18306 - - 0.000000000000000000000000000000000000007699 164.0
HFD2_k127_7114908_2 efflux transmembrane transporter activity K12340 - - 0.00000005109 66.0
HFD2_k127_7121339_0 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 368.0
HFD2_k127_7121339_1 Major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000982 261.0
HFD2_k127_7121339_2 CDGSH-type zinc finger. Function unknown. - - - 0.00002083 47.0
HFD2_k127_7121339_3 conserved protein, contains double-stranded beta-helix domain - - - 0.000959 47.0
HFD2_k127_7132654_0 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008878 420.0
HFD2_k127_7132654_1 Peptidase, M16 K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005767 319.0
HFD2_k127_7132654_2 Peptidase M16 inactive domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000312 258.0
HFD2_k127_7132654_3 endonuclease III K01247 - 3.2.2.21 0.0000000000000000000000000000000000000000000000008053 183.0
HFD2_k127_7132654_4 BAAT / Acyl-CoA thioester hydrolase C terminal - - - 0.000000000000000000000002894 109.0
HFD2_k127_713596_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K16874 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004331 389.0
HFD2_k127_713596_1 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000001548 265.0
HFD2_k127_7146751_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 439.0
HFD2_k127_7146751_1 PFAM band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 336.0
HFD2_k127_7146751_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 332.0
HFD2_k127_7146751_3 - K07403 - - 0.0000000001483 63.0
HFD2_k127_7151643_0 PFAM LOR SDH bifunctional - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004156 456.0
HFD2_k127_7151643_1 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 433.0
HFD2_k127_7151643_2 Amidinotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005626 316.0
HFD2_k127_7151643_3 Zn-dependent hydrolases of the - - - 0.00000000000000000000000000000000000000000000003988 180.0
HFD2_k127_7151643_4 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000008619 173.0
HFD2_k127_7151643_5 Cytidylate kinase-like family - - - 0.0000000000000000000000000000000000003683 150.0
HFD2_k127_7151643_6 - - - - 0.00000000000000000004804 96.0
HFD2_k127_7151643_7 Evidence 5 No homology to any previously reported sequences - - - 0.000000000000000005154 92.0
HFD2_k127_7154459_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 341.0
HFD2_k127_7154459_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005439 327.0
HFD2_k127_7154459_2 X-Pro dipeptidyl-peptidase (S15 family) K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 302.0
HFD2_k127_7154459_3 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000003701 186.0
HFD2_k127_7154459_4 PFAM luciferase-like - - - 0.000000000000000000000000000000000000000000000003473 185.0
HFD2_k127_7154459_5 FecR protein - - - 0.000006514 53.0
HFD2_k127_7168870_0 glycosyl transferase family 39 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000001207 253.0
HFD2_k127_7168870_1 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000008873 171.0
HFD2_k127_7168870_2 MerR, DNA binding K19591 - - 0.0000000000000000000001035 103.0
HFD2_k127_7168870_3 Methyltransferase domain - - - 0.00000000000000006976 83.0
HFD2_k127_7185999_0 ABC transporter, phosphonate, periplasmic substrate-binding protein K02051 - - 0.000000000000007756 86.0
HFD2_k127_7185999_1 Periplasmic or secreted lipoprotein K04065 - - 0.0000000000006961 72.0
HFD2_k127_7185999_2 Ion channel - - - 0.00001762 55.0
HFD2_k127_7192186_0 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009422 547.0
HFD2_k127_7192186_1 all-trans-retinol 13,14-reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 413.0
HFD2_k127_7192186_2 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000002339 271.0
HFD2_k127_7195336_0 Selenoprotein B, glycine betaine sarcosine D-proline reductase family K10672 - 1.21.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009111 295.0
HFD2_k127_7196240_0 Conserved carboxylase domain K01571 - 4.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009249 418.0
HFD2_k127_7196240_1 Substrate binding domain of ABC-type glycine betaine transport system K02051 - - 0.0000000000008945 79.0
HFD2_k127_7196240_2 ABC-type nitrate sulfonate bicarbonate transport - - - 0.000000000006645 76.0
HFD2_k127_7196240_3 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 GO:0003674,GO:0005215 - 0.00002069 54.0
HFD2_k127_7215445_0 PFAM Lytic transglycosylase catalytic K08309 - - 0.00000000000000000000000000000000000000002349 160.0
HFD2_k127_7215445_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000002605 153.0
HFD2_k127_7215445_2 NUDIX domain K03574 - 3.6.1.55 0.0000000000000000000000000006155 119.0
HFD2_k127_7215445_3 Domain of unknown function (DUF4410) - - - 0.000000000000001932 86.0
HFD2_k127_7215445_4 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000002347 72.0
HFD2_k127_7215445_5 peptidase activity, acting on L-amino acid peptides K07004,K09955 - - 0.0001596 53.0
HFD2_k127_7223400_0 Predicted integral membrane protein (DUF2269) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007123 265.0
HFD2_k127_7223400_1 PFAM Glycine sarcosine betaine reductase component B subunits - - - 0.00000000000000000000000000000000000000000000000000000000000000000004883 250.0
HFD2_k127_7223400_2 selenoprotein B, glycine betaine sarcosine D-proline reductase K10672 - 1.21.4.2 0.000000001843 59.0
HFD2_k127_7225758_0 RNA secondary structure unwinding K03724 - - 0.0 1118.0
HFD2_k127_7239927_0 Fibronectin type III-like domain K05349 - 3.2.1.21 2.197e-284 893.0
HFD2_k127_7239927_1 Alpha-L-arabinofuranosidase C-terminal domain K01209 - 3.2.1.55 1.527e-282 874.0
HFD2_k127_7239927_2 Putative esterase K07214 - - 2.999e-211 661.0
HFD2_k127_7239927_3 belongs to the aldehyde dehydrogenase family K13877,K14519 - 1.2.1.26,1.2.1.4 0.00000000000002944 73.0
HFD2_k127_7240969_0 serine-type endopeptidase activity K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004445 514.0
HFD2_k127_7240969_1 Glucose Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 374.0
HFD2_k127_7240969_2 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000002805 241.0
HFD2_k127_7240969_3 - - - - 0.000000000000000000000000000354 123.0
HFD2_k127_7240969_4 YCII-related domain - - - 0.0000000000000000000000001148 113.0
HFD2_k127_7240969_5 EamA-like transporter family K03298 - - 0.0000000001363 72.0
HFD2_k127_7245369_0 N-methylhydantoinase B acetone carboxylase alpha subunit K01474 - 3.5.2.14 8.59e-196 625.0
HFD2_k127_7245369_1 NMT1-like family K02051 - - 0.000000000002051 77.0
HFD2_k127_7245369_2 Belongs to the peptidase M24B family - - - 0.0005772 48.0
HFD2_k127_7248426_0 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 307.0
HFD2_k127_7248698_0 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.0000000000000000000000002962 117.0
HFD2_k127_7248698_1 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000001563 106.0
HFD2_k127_7248698_2 Acetyl-CoA acetyltransferase - - - 0.0000000003156 66.0
HFD2_k127_7253358_0 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 312.0
HFD2_k127_7253358_1 Mo-molybdopterin cofactor metabolic process K03638 - 2.7.7.75 0.00000000000000000000000000000000000000000000000000000004458 200.0
HFD2_k127_7253358_2 COGs COG2929 conserved K09803 - - 0.00002366 50.0
HFD2_k127_7255234_0 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005311 493.0
HFD2_k127_7255234_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 453.0
HFD2_k127_7255234_10 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.00009176 48.0
HFD2_k127_7255234_11 Tripartite tricarboxylate transporter family receptor - - - 0.0001548 46.0
HFD2_k127_7255234_2 cobalamin synthesis CobW domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 342.0
HFD2_k127_7255234_3 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 313.0
HFD2_k127_7255234_4 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006133 263.0
HFD2_k127_7255234_5 Enoyl-(Acyl carrier protein) reductase K00059,K18009,K19548 - 1.1.1.100,1.1.1.304,1.1.1.385,1.1.1.76 0.0000000000000000000000000000000000000000000000000000006001 209.0
HFD2_k127_7255234_6 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000000003953 120.0
HFD2_k127_7255234_7 O-methyltransferase K00588 - 2.1.1.104 0.00000000000001068 76.0
HFD2_k127_7255234_8 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.000000000000377 80.0
HFD2_k127_7255234_9 Phosphoenolpyruvate phosphomutase - - - 0.000003141 53.0
HFD2_k127_7259403_0 pyruvate dehydrogenase (acetyl-transferring) activity K00163 - 1.2.4.1 0.0 1141.0
HFD2_k127_7259403_1 mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth K15738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 447.0
HFD2_k127_7259403_2 PFAM Biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.000000000000000000000000000000000000000000000000000008486 199.0
HFD2_k127_7259403_3 Calcineurin-like phosphoesterase K07313 - 3.1.3.16 0.00000000000000000000000000000000000000000000000002818 189.0
HFD2_k127_7259403_4 Component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.000000000000000000000000000000000002663 146.0
HFD2_k127_7275071_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01576,K01652 - 2.2.1.6,4.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 343.0
HFD2_k127_7275071_1 Catalyzes the hydrolytic cleavage of a carbon-halogen bond in N-ethylammeline K12960 - 3.5.4.28,3.5.4.31 0.00000000000000001573 90.0
HFD2_k127_7275071_2 Amidohydrolase K07045 - - 0.00000000001161 66.0
HFD2_k127_7287154_0 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000000000001578 203.0
HFD2_k127_7287154_1 decarboxylase K01607 - 4.1.1.44 0.00000000000000001528 90.0
HFD2_k127_7287154_2 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000002125 89.0
HFD2_k127_72874_0 PFAM tRNA synthetases class II (D, K and N) K01893 - 6.1.1.22 1.895e-198 629.0
HFD2_k127_72874_1 Protein of unknown function (DUF1232) - - - 0.0000000000000000000000000000000008248 134.0
HFD2_k127_72874_2 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.0000000000000000008266 88.0
HFD2_k127_7288646_0 electron transfer flavoprotein, alpha subunit K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002265 287.0
HFD2_k127_7288646_1 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007524 266.0
HFD2_k127_7288646_2 Electron transfer flavoprotein domain K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000002329 238.0
HFD2_k127_7288646_3 Phenylacetate-CoA oxygenase K02609 - 1.14.13.149 0.000000009758 59.0
HFD2_k127_7304428_0 alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 422.0
HFD2_k127_7304428_1 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K16079 - - 0.000000002514 68.0
HFD2_k127_7311799_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 596.0
HFD2_k127_7311799_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 458.0
HFD2_k127_7311799_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 300.0
HFD2_k127_7311799_3 Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000003718 261.0
HFD2_k127_7311799_4 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000000000000000006265 206.0
HFD2_k127_7337631_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002749 470.0
HFD2_k127_7337631_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 404.0
HFD2_k127_7337631_2 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000002466 260.0
HFD2_k127_7337631_3 excinuclease ABC - - - 0.000000000000000000000000004589 116.0
HFD2_k127_7337631_4 50S ribosomal protein L31 K02909 - - 0.00000000000000000000000003667 108.0
HFD2_k127_7386166_0 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 504.0
HFD2_k127_7386166_1 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 310.0
HFD2_k127_7386166_2 Glycerophosphoryl diester phosphodiesterase family K01113,K01126 - 3.1.3.1,3.1.4.46 0.00000000000000000000000000000000000000000000000000000001606 219.0
HFD2_k127_7386166_3 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls - - - 0.0000000000000000000000000000000000000000000000000007016 200.0
HFD2_k127_7386166_4 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000001286 162.0
HFD2_k127_7386166_5 Predicted permease K07089 - - 0.000000000000000000000000000000004067 136.0
HFD2_k127_7386166_6 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000004081 113.0
HFD2_k127_7386166_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000008492 63.0
HFD2_k127_7389052_0 PFAM glycoside hydrolase family 77 K00705 - 2.4.1.25 9.133e-201 647.0
HFD2_k127_7389052_1 - - - - 0.0000000000000000000000008516 110.0
HFD2_k127_7389052_2 SMART alpha amylase, catalytic sub domain K05343 - 3.2.1.1,5.4.99.16 0.0000006516 51.0
HFD2_k127_7399767_0 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000001679 198.0
HFD2_k127_7399767_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000002315 192.0
HFD2_k127_7399767_2 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.0000000000000000000000000000001959 125.0
HFD2_k127_7428076_0 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.000000000000000000000000000000000000009839 145.0
HFD2_k127_7428076_1 FAD linked oxidase K18930 - - 0.00000000000000000000000001242 111.0
HFD2_k127_7428076_2 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.000000000001438 68.0
HFD2_k127_7428076_3 thiamine-containing compound biosynthetic process K02051 - - 0.0000001939 60.0
HFD2_k127_7428076_4 NMT1-like family - - - 0.00002451 55.0
HFD2_k127_7439062_0 Phosphate acyltransferases K05939 - 2.3.1.40,6.2.1.20 1.909e-209 666.0
HFD2_k127_7439062_1 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 351.0
HFD2_k127_7446886_0 COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family - - - 0.00000000000000000000000000000000000000005144 158.0
HFD2_k127_7446886_1 - - - - 0.0000000000000000000000000000002404 131.0
HFD2_k127_7446886_2 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000001882 130.0
HFD2_k127_7446886_3 Protein of unknown function DUF72 - - - 0.00000007591 57.0
HFD2_k127_7448933_0 Conserved carboxylase domain K01571 - 4.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000801 417.0
HFD2_k127_7448933_1 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.000000000000000000000000002759 112.0
HFD2_k127_7448933_2 ABC transporter substrate-binding protein K02051 - - 0.000000000000014 82.0
HFD2_k127_7467284_0 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 9.33e-244 764.0
HFD2_k127_7467284_1 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 332.0
HFD2_k127_7467284_2 methylamine metabolic process K15977 - - 0.00000000004386 70.0
HFD2_k127_7509644_0 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 5.761e-195 621.0
HFD2_k127_7509644_1 Uncharacterized conserved protein (DUF2267) - - - 0.000000000000000000000000000000000000000000001454 172.0
HFD2_k127_7509644_2 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000008074 160.0
HFD2_k127_7513044_0 Molydopterin dinucleotide binding domain K10700,K17050 - 1.17.99.2 1.26e-236 761.0
HFD2_k127_7513044_1 Belongs to the UbiD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 434.0
HFD2_k127_7513044_2 Molydopterin dinucleotide binding domain K10700,K17050 - 1.17.99.2 0.00000000000000000000000000000000000000000000000000000000000000000001113 240.0
HFD2_k127_7513044_3 Peptidase family U32 - - - 0.000000000000000000000000000000000000000000000000000000000001356 224.0
HFD2_k127_7513044_4 Molydopterin dinucleotide binding domain K10700,K17050 - 1.17.99.2 0.000000000000000000000000000000000000000000001018 169.0
HFD2_k127_7513378_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004048 405.0
HFD2_k127_7513378_1 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020 - 1.1.1.31 0.0000000000005248 69.0
HFD2_k127_75486_0 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000003614 164.0
HFD2_k127_7551155_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 4.809e-276 860.0
HFD2_k127_7551155_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003777 565.0
HFD2_k127_7551155_10 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000009084 204.0
HFD2_k127_7551155_11 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000002374 178.0
HFD2_k127_7551155_12 TIGRFAM DNA binding domain - - - 0.000000000005319 68.0
HFD2_k127_7551155_13 - - - - 0.00000000003459 68.0
HFD2_k127_7551155_14 - - - - 0.00001178 51.0
HFD2_k127_7551155_2 GDP-mannose 4,6 dehydratase K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 474.0
HFD2_k127_7551155_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 434.0
HFD2_k127_7551155_4 PFAM PfkB domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004326 387.0
HFD2_k127_7551155_5 Glycosyltransferase like family 2 K10012 - 2.4.2.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004914 384.0
HFD2_k127_7551155_6 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007806 366.0
HFD2_k127_7551155_7 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009903 351.0
HFD2_k127_7551155_8 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005614 340.0
HFD2_k127_7551155_9 TIGRFAM signal peptidase I K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000009031 259.0
HFD2_k127_7556302_0 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 2.955e-265 835.0
HFD2_k127_7556302_1 tail specific protease K03797 GO:0003674,GO:0003824,GO:0004175,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009653,GO:0009987,GO:0016787,GO:0019538,GO:0023052,GO:0030154,GO:0030288,GO:0030313,GO:0030435,GO:0031975,GO:0032502,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043603,GO:0043900,GO:0043902,GO:0043934,GO:0044237,GO:0044238,GO:0044464,GO:0046983,GO:0048518,GO:0048522,GO:0048646,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0140096,GO:1900190,GO:1900192,GO:1901564 3.4.21.102 0.000001581 57.0
HFD2_k127_7582624_0 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000003353 197.0
HFD2_k127_7582624_1 MmgE/PrpD family K01720 - 4.2.1.79 0.0000000000006492 72.0
HFD2_k127_7617055_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0016829,GO:0016835,GO:0016838,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001842 273.0
HFD2_k127_7617055_2 Major Facilitator Superfamily - - - 0.000000000000000000000001765 117.0
HFD2_k127_7632004_0 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 7.253e-225 705.0
HFD2_k127_7632004_1 peptidase - - - 0.00000000000000000000000000000000005282 143.0
HFD2_k127_7632004_2 Ferredoxin - - - 0.000000000000000000000000002537 116.0
HFD2_k127_7661422_0 Aconitase family (aconitate hydratase) K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 492.0
HFD2_k127_7661422_1 Belongs to the LeuD family K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000001614 155.0
HFD2_k127_7666276_0 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000000000000000000000000000000000000000000000000000007338 222.0
HFD2_k127_7666276_1 oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000001162 226.0
HFD2_k127_76722_0 MotA/TolQ/ExbB proton channel family K03561 - - 0.00000000000000000000000002143 117.0
HFD2_k127_76722_1 repeat protein - - - 0.00000000000000000001049 104.0
HFD2_k127_76722_2 Biopolymer transport protein ExbD TolR K03559 - - 0.00000000000000000001641 96.0
HFD2_k127_76722_3 repeat protein - - - 0.00000000004473 75.0
HFD2_k127_76722_4 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00001737 56.0
HFD2_k127_7682673_0 Homospermidine synthase K00808 - 2.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 350.0
HFD2_k127_7682673_1 Protein involved in outer membrane biogenesis K07289 - - 0.000000000000000000637 101.0
HFD2_k127_7682673_2 AsmA-like C-terminal region K07289 - - 0.0001106 55.0
HFD2_k127_7699872_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1445.0
HFD2_k127_7699872_1 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 287.0
HFD2_k127_7699872_2 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004621 271.0
HFD2_k127_7699872_3 Sulfurtransferase - - - 0.000000000000000000008631 93.0
HFD2_k127_7699872_4 Outer membrane efflux protein - - - 0.00000000000008681 78.0
HFD2_k127_7699872_5 Hsp90 protein K04079 - - 0.0002737 51.0
HFD2_k127_7734423_0 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000967 210.0
HFD2_k127_7734423_1 NHL repeat - - - 0.00000000000001899 75.0
HFD2_k127_7734423_2 COG0477 Permeases of the major facilitator superfamily K08151 - - 0.00007036 55.0
HFD2_k127_7734552_0 PFAM Ribonuclease BN-like family K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 323.0
HFD2_k127_7734552_1 Histidine kinase K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006861 294.0
HFD2_k127_7734552_2 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004816 251.0
HFD2_k127_7734552_3 PFAM Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000006363 115.0
HFD2_k127_7734552_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000546 102.0
HFD2_k127_7734552_5 - - - - 0.0000000000002243 74.0
HFD2_k127_7734552_6 Histidine kinase K07710,K10125 - 2.7.13.3 0.0000009923 55.0
HFD2_k127_7734552_7 - - - - 0.0008326 44.0
HFD2_k127_77449_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 3.695e-246 784.0
HFD2_k127_77449_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K16877 - 1.3.99.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009803 544.0
HFD2_k127_77449_10 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000006181 205.0
HFD2_k127_77449_11 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000002901 198.0
HFD2_k127_77449_12 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.0000000000000000000000000000000000000000000002725 179.0
HFD2_k127_77449_13 Transglutaminase/protease-like homologues - - - 0.0000001229 53.0
HFD2_k127_77449_2 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K16874 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 439.0
HFD2_k127_77449_3 CO dehydrogenase flavoprotein domain protein K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006187 285.0
HFD2_k127_77449_4 PFAM ABC transporter related K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004509 261.0
HFD2_k127_77449_5 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000005515 261.0
HFD2_k127_77449_6 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000001095 225.0
HFD2_k127_77449_7 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.000000000000000000000000000000000000000000000000000000000000001873 235.0
HFD2_k127_77449_8 membrane K02050 - - 0.000000000000000000000000000000000000000000000000000000000003988 216.0
HFD2_k127_77449_9 succinylglutamate desuccinylase aspartoacylase K07402 - - 0.0000000000000000000000000000000000000000000000000000000001857 208.0
HFD2_k127_77729_0 Domain of Unknown Function (DUF748) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 428.0
HFD2_k127_77729_1 - - - - 0.000000003351 58.0
HFD2_k127_7773762_0 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006078 537.0
HFD2_k127_7773762_1 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005853 443.0
HFD2_k127_7773762_2 Protein of unknown function (DUF1348) K09958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007279 299.0
HFD2_k127_7773762_3 Protein of unknown function (DUF1624) - - - 0.0000000000000000000000000000000000003964 147.0
HFD2_k127_7773762_4 light absorption - - - 0.000000001931 60.0
HFD2_k127_7773762_5 COGs COG4299 conserved - - - 0.000002014 51.0
HFD2_k127_7773762_6 Psort location CytoplasmicMembrane, score 10.00 - - - 0.00002032 48.0
HFD2_k127_7773762_7 - - - - 0.00004623 51.0
HFD2_k127_7776735_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003289 440.0
HFD2_k127_7776735_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004105 280.0
HFD2_k127_7776735_2 Peptidase family M23 - - - 0.0000000000000000000004504 96.0
HFD2_k127_7789638_0 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 5.819e-245 760.0
HFD2_k127_7789638_2 - - - - 0.0000315 50.0
HFD2_k127_7795207_0 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 6.595e-207 652.0
HFD2_k127_7795207_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 514.0
HFD2_k127_7795207_2 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009293 445.0
HFD2_k127_7795207_3 Belongs to the UbiD family K03182,K16874 - 4.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006997 375.0
HFD2_k127_7795207_4 Catalyzes the reversible oxidation of malate to oxaloacetate K00016,K00024 - 1.1.1.27,1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 363.0
HFD2_k127_7795207_5 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000195 260.0
HFD2_k127_7795207_6 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000002499 176.0
HFD2_k127_7795207_7 ABC transporter, phosphonate, periplasmic substrate-binding protein K02051 - - 0.0000000009562 71.0
HFD2_k127_7795207_8 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000001626 53.0
HFD2_k127_7813186_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 456.0
HFD2_k127_7813186_1 VWA domain containing CoxE-like protein K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005318 261.0
HFD2_k127_7813186_2 peptide deformylase activity K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000001112 234.0
HFD2_k127_7813186_3 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000003543 169.0
HFD2_k127_7813186_4 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.00007088 48.0
HFD2_k127_7813186_5 tetratricopeptide repeat - - - 0.0005731 50.0
HFD2_k127_781523_0 carbohydrate transport K02027,K10236 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 415.0
HFD2_k127_781523_1 ATPase activity K10111,K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004112 364.0
HFD2_k127_781523_2 PFAM binding-protein-dependent transport systems inner membrane component K02025,K10237 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 333.0
HFD2_k127_781523_3 Binding-protein-dependent transport system inner membrane component K02026,K10238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003804 309.0
HFD2_k127_781523_4 mannosylglycerate metabolic process K05947,K07026 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050897 2.4.1.217,3.1.3.70 0.00000000000000000000000000000000000000000000000000000000000000006295 232.0
HFD2_k127_781523_5 transferase activity, transferring glycosyl groups K09118,K13693,K21349 - 2.4.1.266,2.4.1.268 0.000000000000000000000000000000000000000000000000000000003409 202.0
HFD2_k127_781523_6 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000001825 102.0
HFD2_k127_7831903_0 Alpha amylase, C-terminal all-beta domain K00700 - 2.4.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004717 380.0
HFD2_k127_7831903_1 iron assimilation K07223 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 338.0
HFD2_k127_7831903_2 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000002443 189.0
HFD2_k127_7848661_0 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000002409 238.0
HFD2_k127_7848661_1 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000646 185.0
HFD2_k127_7848661_2 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate K02437 GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 - 0.000000000000000000000000000000002694 132.0
HFD2_k127_7848661_3 Transcriptional regulator - - - 0.000000000000000000000000000002159 126.0
HFD2_k127_7848661_4 Lipid A biosynthesis K02517 - 2.3.1.241 0.00000000000000000000000000002219 131.0
HFD2_k127_7848661_5 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K06034 - 4.1.1.79 0.00000000000000000000000000006617 123.0
HFD2_k127_7848661_6 Belongs to the TPP enzyme family K13039 - 4.1.1.79 0.000000000000000000000003574 115.0
HFD2_k127_7848661_7 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000005056 85.0
HFD2_k127_7848661_8 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589,K13052 - - 0.000000000001214 72.0
HFD2_k127_78705_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 359.0
HFD2_k127_78705_1 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000000000000000000000000000005519 178.0
HFD2_k127_7889506_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 562.0
HFD2_k127_7889506_1 Dehydratase K14449,K18290 - 4.2.1.148,4.2.1.56 0.00000000000000000000000000000000000000000000000000000000003158 209.0
HFD2_k127_7889506_2 PFAM major facilitator superfamily MFS_1 - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.000000006296 68.0
HFD2_k127_7890025_0 TIM-barrel fold metal-dependent hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000003397 218.0
HFD2_k127_7890025_1 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000004019 144.0
HFD2_k127_7890025_2 Creatinase/Prolidase N-terminal domain - - - 0.00000001033 67.0
HFD2_k127_7890269_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 496.0
HFD2_k127_7890269_1 ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000285 122.0
HFD2_k127_7897153_0 Bacterial DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1203.0
HFD2_k127_7897153_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.381e-227 721.0
HFD2_k127_7897153_10 NUDIX domain K03574 - 3.6.1.55 0.00000000000000004091 89.0
HFD2_k127_7897153_2 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 386.0
HFD2_k127_7897153_3 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005147 274.0
HFD2_k127_7897153_4 ABC transporter K15738 - - 0.00000000000000000000000000000000000000000000000002952 184.0
HFD2_k127_7897153_5 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.0000000000000000000000000000000000000000000000001326 181.0
HFD2_k127_7897153_6 deacetylase K22278 - 3.5.1.104 0.000000000000000000000000000000000000000001299 168.0
HFD2_k127_7897153_7 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000001641 145.0
HFD2_k127_7897153_8 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.000000000000000000000000000000000001876 145.0
HFD2_k127_7897153_9 Ribosomal protein L35 K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000001491 88.0
HFD2_k127_7897514_0 NADH ubiquinone oxidoreductase subunit 5 (Chain L) multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 564.0
HFD2_k127_7897514_1 formate dehydrogenase (NAD+) activity K00336,K18006 - 1.12.1.2,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005715 442.0
HFD2_k127_7897514_2 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 406.0
HFD2_k127_7897514_3 quinone binding K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 368.0
HFD2_k127_7897514_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000000000000008846 128.0
HFD2_k127_7897514_5 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000004918 108.0
HFD2_k127_7897514_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.0000000000005788 69.0
HFD2_k127_7908699_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 417.0
HFD2_k127_7908699_1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.0000000000000000000000000000000000000000000000008505 181.0
HFD2_k127_7918374_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000007299 172.0
HFD2_k127_7918374_1 Domain of unknown function DUF123 - - - 0.000000000000000000005104 102.0
HFD2_k127_7925248_0 AMP-binding enzyme C-terminal domain K02363,K04116 - 2.7.7.58,6.3.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007544 333.0
HFD2_k127_7925248_1 NMT1-like family - - - 0.0000000000000000000000000000004163 134.0
HFD2_k127_7926834_0 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001049 290.0
HFD2_k127_7926834_1 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000003346 244.0
HFD2_k127_7926834_2 PFAM Tetratricopeptide repeat - - - 0.00000000000000000000000003026 113.0
HFD2_k127_7926834_3 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000001462 95.0
HFD2_k127_7926834_4 Sulphur oxidation protein SoxZ K17227 - - 0.0000000000000000006181 90.0
HFD2_k127_7931898_0 PAS domain K13598 - 2.7.13.3 1.811e-218 700.0
HFD2_k127_7931898_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 464.0
HFD2_k127_7931898_2 UDP-3-O-acyl N-acetylglycosamine deacetylase K02535,K13599 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 391.0
HFD2_k127_7931898_3 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 329.0
HFD2_k127_7931898_4 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 320.0
HFD2_k127_7931898_5 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.00000000000000000000000000000000000000000000000002459 185.0
HFD2_k127_7931898_6 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000007616 149.0
HFD2_k127_7931898_7 Filamentation induced by cAMP protein fic - - - 0.00000000000000000000000000000000003773 136.0
HFD2_k127_7931898_8 Protein of unknown function (DUF2905) - - - 0.00000000000000000000274 94.0
HFD2_k127_7931898_9 Uncharacterized conserved protein (DUF2203) - - - 0.000000000000000000009444 97.0
HFD2_k127_7933076_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 2.204e-293 914.0
HFD2_k127_7933076_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007278 572.0
HFD2_k127_7933076_2 NMT1-like family K02051 - - 0.0000000000005362 80.0
HFD2_k127_7940497_0 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005462 375.0
HFD2_k127_7940497_1 lactoylglutathione lyase activity - - - 0.000000000000000000000000292 109.0
HFD2_k127_7940497_2 Required for chromosome condensation and partitioning K03529 - - 0.0002861 52.0
HFD2_k127_7945121_0 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 302.0
HFD2_k127_7945121_1 ethanolamine utilization protein K04019 GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0030091,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009,GO:0071704,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000001287 241.0
HFD2_k127_7945121_2 nuclear chromosome segregation - - - 0.0000000000000000000000000000000000000000000000000000000005279 231.0
HFD2_k127_7952212_0 2-methylcitrate dehydratase K01720 GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0046459,GO:0047547,GO:0071704 4.2.1.79 8.224e-224 702.0
HFD2_k127_7952212_1 Citrate synthase, C-terminal domain K01659 - 2.3.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000842 509.0
HFD2_k127_7952212_2 Phosphoenolpyruvate phosphomutase K20454 - 4.1.3.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 291.0
HFD2_k127_7952212_3 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000001569 120.0
HFD2_k127_7959504_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.064e-315 995.0
HFD2_k127_7959504_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.632e-268 850.0
HFD2_k127_7959504_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005465 546.0
HFD2_k127_7959504_3 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007757 522.0
HFD2_k127_7959504_4 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006756 331.0
HFD2_k127_7959504_5 FeS assembly protein SufB K07033,K09014 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009536,GO:0009842,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840 - 0.0000000000000000000000000000000000000000000000000000000000000000001312 232.0
HFD2_k127_7959504_6 PpiC-type peptidyl-prolyl cis-trans isomerase K03771 - 5.2.1.8 0.00000000000000000000000000000000000001492 160.0
HFD2_k127_7959504_7 Iron-sulphur cluster biosynthesis - - - 0.00000000000000000000000000003221 122.0
HFD2_k127_7963108_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 342.0
HFD2_k127_7963108_1 Protein of unknown function (DUF433) - - - 0.00000000000000000000003536 100.0
HFD2_k127_7963108_2 NMT1/THI5 like K02051 - - 0.000006902 57.0
HFD2_k127_7963108_3 - - - - 0.0003443 44.0
HFD2_k127_79655_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007999 258.0
HFD2_k127_79655_1 FKBP-type peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.00000000000000000000000000000000000004231 149.0
HFD2_k127_79655_2 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000004995 115.0
HFD2_k127_7966943_0 - - - - 0.0000000000000000000000000000002155 132.0
HFD2_k127_7966943_1 - - - - 0.0000000000000000000000002951 114.0
HFD2_k127_7968142_0 N-methylhydantoinase B acetone carboxylase, alpha subunit K01474 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007349 370.0
HFD2_k127_7968142_1 ornithine cyclodeaminase K01750 - 4.3.1.12 0.000000000000000000000000000000000000000000000000000001039 200.0
HFD2_k127_7968142_2 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000575 166.0
HFD2_k127_7971972_0 proline dipeptidase activity - - - 1.498e-239 744.0
HFD2_k127_7971972_1 Tripartite tricarboxylate transporter TctA family - - - 3.454e-207 655.0
HFD2_k127_7971972_10 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K19802 - 5.1.1.20 0.000000000000000000000000000000000000000000000000002845 196.0
HFD2_k127_7971972_11 Smr domain K07456 GO:0000018,GO:0008150,GO:0009892,GO:0010605,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0080090 - 0.000000000000000000000000001804 116.0
HFD2_k127_7971972_13 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.00000001079 58.0
HFD2_k127_7971972_14 PFAM Cupin - - - 0.00000536 54.0
HFD2_k127_7971972_2 Ammonium Transporter Family K03320 - - 7.139e-196 622.0
HFD2_k127_7971972_3 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007599 347.0
HFD2_k127_7971972_4 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K00945,K02945,K03527 - 1.17.7.4,2.7.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003985 341.0
HFD2_k127_7971972_5 MmgE/PrpD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 342.0
HFD2_k127_7971972_6 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 297.0
HFD2_k127_7971972_7 Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005524 263.0
HFD2_k127_7971972_8 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001911 247.0
HFD2_k127_7971972_9 NMT1/THI5 like - - - 0.0000000000000000000000000000000000000000000000000000000004195 215.0
HFD2_k127_7972609_0 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K02052 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 292.0
HFD2_k127_7972609_1 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000000000000000000000000000683 178.0
HFD2_k127_7972609_2 CAAX protease self-immunity - - - 0.00000000000000000000000000000001206 137.0
HFD2_k127_7979536_0 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008563 261.0
HFD2_k127_7979536_1 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000003157 180.0
HFD2_k127_7981191_0 geranylgeranyl reductase activity - - - 1.726e-225 706.0
HFD2_k127_7981191_1 Polysaccharide pyruvyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 406.0
HFD2_k127_7988482_0 PFAM Cytochrome b b6 domain - - - 1.013e-196 626.0
HFD2_k127_7988482_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 538.0
HFD2_k127_7988482_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K07306,K17050 - 1.7.5.1,1.8.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 496.0
HFD2_k127_7988482_3 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004661 308.0
HFD2_k127_7988482_4 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.000000000000000000000000001552 120.0
HFD2_k127_8003714_0 Nucleotidyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000007727 232.0
HFD2_k127_8003714_1 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000001541 156.0
HFD2_k127_8007446_0 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008333 556.0
HFD2_k127_8007446_1 Bacterial regulatory protein, Fis family K02481,K07713,K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006488 453.0
HFD2_k127_8007446_10 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000155 179.0
HFD2_k127_8007446_11 response regulator K10943 - - 0.000000000000000000000000002247 129.0
HFD2_k127_8007446_2 extracellular solute-binding protein, family 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004095 429.0
HFD2_k127_8007446_3 PFAM PrpF protein K20451 - 5.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006523 413.0
HFD2_k127_8007446_4 Peptidase family M28 K06016 - 3.5.1.6,3.5.1.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 359.0
HFD2_k127_8007446_5 TOBE domain K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004788 332.0
HFD2_k127_8007446_6 PFAM Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000001773 237.0
HFD2_k127_8007446_7 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000007859 229.0
HFD2_k127_8007446_8 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000101 197.0
HFD2_k127_8007446_9 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000681 172.0
HFD2_k127_8010751_0 Glucose dehydrogenase C-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 371.0
HFD2_k127_8010751_1 Sir2 family K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000001277 244.0
HFD2_k127_8010751_2 FKBP-type peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.00000000000000000000000000000000000002004 150.0
HFD2_k127_8010751_3 Bacterial PH domain - - - 0.000000000000000000000000000000000002208 143.0
HFD2_k127_8021090_0 MFS/sugar transport protein - - - 0.00000000000000000000000000000000000000000000001511 187.0
HFD2_k127_8021090_1 SMART HNH nuclease K07451 - - 0.0000000000000000000000000000000001751 134.0
HFD2_k127_8021090_2 haloacid dehalogenase-like hydrolase - - - 0.0001018 53.0
HFD2_k127_80224_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 5.071e-289 902.0
HFD2_k127_80224_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 1.87e-256 801.0
HFD2_k127_80224_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.000000000000000000000000000000000000000000004814 168.0
HFD2_k127_80224_3 - K09771 - - 0.0000000000000000000000000000000000002341 143.0
HFD2_k127_80224_4 Amino acid permease - - - 0.000001989 50.0
HFD2_k127_8025351_0 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 309.0
HFD2_k127_8025351_1 Maleate cis-trans isomerase K01799 - 5.2.1.1 0.0000000004015 70.0
HFD2_k127_8026540_0 Cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005926 272.0
HFD2_k127_8026540_1 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000000000000000001032 136.0
HFD2_k127_8026540_2 transcriptional regulator - - - 0.000000000000000000000000000002125 130.0
HFD2_k127_8026540_3 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.0000000000000000001253 103.0
HFD2_k127_8030386_0 Belongs to the UbiD family K03182 - 4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009469 445.0
HFD2_k127_8030386_1 NMT1-like family K02051 - - 0.0000003273 61.0
HFD2_k127_8035585_0 acetyl-coa acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004077 318.0
HFD2_k127_8035585_1 4,5-dihydroxyphthalate decarboxylase K04102 - 4.1.1.55 0.00000000000000000000000000000000000000000000000000303 193.0
HFD2_k127_8035585_2 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000000000000000000000001098 136.0
HFD2_k127_8035585_3 Luciferase-like monooxygenase - - - 0.00001818 50.0
HFD2_k127_8035585_4 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 GO:0003674,GO:0005215 - 0.0004395 45.0
HFD2_k127_8043028_0 FAH family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001058 283.0
HFD2_k127_8043028_1 Amidohydrolase K03392 - 4.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000005215 264.0
HFD2_k127_8043028_2 DNA polymerase III, delta' K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000002866 184.0
HFD2_k127_8043028_3 SMART phospholipase D Transphosphatidylase - - - 0.0000000000000000000000000004128 120.0
HFD2_k127_8043028_4 Nucleic acid binding - - - 0.0006339 51.0
HFD2_k127_8043028_5 Belongs to the MEMO1 family K06990 - - 0.0007365 43.0
HFD2_k127_80435_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 437.0
HFD2_k127_80435_1 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 313.0
HFD2_k127_80435_2 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000001545 205.0
HFD2_k127_80435_3 Glyoxalase-like domain - - - 0.00000000000000000000002277 104.0
HFD2_k127_80435_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000001583 59.0
HFD2_k127_8054657_0 - - - - 0.00000000000000007621 83.0
HFD2_k127_8055946_0 OB-fold nucleic acid binding domain K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 387.0
HFD2_k127_8055946_1 Peptidase, M23 - - - 0.0000000000000000000000000000000000000000002572 172.0
HFD2_k127_8068068_0 GTP-binding protein K06207 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005306 250.0
HFD2_k127_8068068_1 Glyoxalase-like domain K06996 - - 0.000000000000000000000000000000000001202 141.0
HFD2_k127_8068068_2 ABC transporter substrate-binding protein K15551 - - 0.00000000000001935 84.0
HFD2_k127_8068068_3 cell redox homeostasis K03671 - - 0.0000000000001043 74.0
HFD2_k127_8068068_4 Protein of unknown function - - - 0.000004303 59.0
HFD2_k127_8085573_0 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004658 272.0
HFD2_k127_8085573_1 Pfam:AmoA K07120 - - 0.000000000000004194 79.0
HFD2_k127_8095129_1 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000000000000000000000000002652 132.0
HFD2_k127_8095129_2 PFAM D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.00009159 48.0
HFD2_k127_8098855_0 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K00666,K01897,K12507 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 416.0
HFD2_k127_810770_0 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000009258 223.0
HFD2_k127_810770_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0000000000000000000000000000001552 125.0
HFD2_k127_810770_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000001436 115.0
HFD2_k127_810770_3 Protein of unknown function (DUF503) K09764 - - 0.00000000000000000003964 93.0
HFD2_k127_8108170_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 512.0
HFD2_k127_8108170_1 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000001185 248.0
HFD2_k127_8108170_2 photosynthesis - - - 0.00000000000000000000000000000000000000000000001013 175.0
HFD2_k127_8108170_3 Belongs to the aldehyde dehydrogenase family K22187 - - 0.0000000000000002161 78.0
HFD2_k127_8111081_0 Xanthine dehydrogenase K03520 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 449.0
HFD2_k127_8111081_1 Coenzyme A transferase K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004498 336.0
HFD2_k127_8111081_2 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000354 257.0
HFD2_k127_8111081_3 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000002263 227.0
HFD2_k127_8111081_4 Coenzyme A transferase K01040 - 2.8.3.12 0.000000000000000000000000264 106.0
HFD2_k127_8111081_5 Haem-degrading K11477 - - 0.0000000000000003448 83.0
HFD2_k127_8145481_0 N-methylhydantoinase A acetone carboxylase, beta subunit K01473 - 3.5.2.14 4.904e-205 658.0
HFD2_k127_8145481_1 CoA-transferase family III K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 329.0
HFD2_k127_8145481_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000009904 184.0
HFD2_k127_8145481_3 MmgE/PrpD family - - - 0.0000000000000000000000000000000000000000006493 175.0
HFD2_k127_8145481_4 with the TIM-barrel fold - - - 0.00000000000000000000000000000000596 141.0
HFD2_k127_8145481_5 - - - - 0.00000000000007185 84.0
HFD2_k127_8145481_6 Creatinase/Prolidase N-terminal domain - - - 0.00000000001573 67.0
HFD2_k127_8146358_0 gluconolactonase activity K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000652 585.0
HFD2_k127_8146358_1 SelR domain K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000001135 246.0
HFD2_k127_8146358_2 Cupin 2, conserved barrel domain protein K11477 - - 0.00000000004286 63.0
HFD2_k127_8150562_0 NADH dehydrogenase (ubiquinone) activity K14089 - - 2.534e-247 772.0
HFD2_k127_8150562_1 Proton-conducting membrane transporter K12141 GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0033554,GO:0044425,GO:0044464,GO:0050896,GO:0051716,GO:0071944 - 7.606e-206 650.0
HFD2_k127_8150562_2 Belongs to the D-alanine--D-alanine ligase family K01921 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008716,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 456.0
HFD2_k127_8150562_3 NADH dehydrogenase K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 442.0
HFD2_k127_8150562_4 ABC-type branched-chain amino acid transport K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008898 413.0
HFD2_k127_8150562_5 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003484 329.0
HFD2_k127_8150562_6 Hydrogenase 4 membrane K12140 GO:0008150,GO:0040007 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002186 280.0
HFD2_k127_8150562_7 Proton-conducting membrane transporter K12137,K15828 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000366 174.0
HFD2_k127_8150562_8 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000183 100.0
HFD2_k127_8150562_9 protein homooligomerization - - - 0.000000000832 68.0
HFD2_k127_8157331_0 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 363.0
HFD2_k127_8157331_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005651 329.0
HFD2_k127_8157331_2 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000001386 180.0
HFD2_k127_8157331_3 Histidine kinase - - - 0.0000000000000000000000000004191 130.0
HFD2_k127_8157331_4 Peptidase family M48 - - - 0.000000000000004552 83.0
HFD2_k127_8168718_0 xanthine dehydrogenase a b hammerhead K11177 - 1.17.1.4 4.105e-246 783.0
HFD2_k127_8168718_1 PFAM Molybdopterin dehydrogenase, FAD-binding K11178 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 453.0
HFD2_k127_8168718_2 formate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001428 245.0
HFD2_k127_8168718_3 2Fe-2S -binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000008211 239.0
HFD2_k127_8168718_4 Conserved carboxylase domain K01571 - 4.1.1.3 0.0000000000000000000000000000000000000000000000000000000000008683 219.0
HFD2_k127_8168718_5 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000003657 163.0
HFD2_k127_8168718_6 - - - - 0.0000000000000000000000000003708 119.0
HFD2_k127_8172071_0 virulence factor MVIN family protein K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007042 512.0
HFD2_k127_8172071_1 PFAM UBA THIF-type NAD FAD binding protein K21029,K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004841 501.0
HFD2_k127_8172071_2 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034,K15582,K16201 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002753 264.0
HFD2_k127_8172071_3 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.00000000000000000000000000000000000000000000000005087 183.0
HFD2_k127_8172071_4 nitrogen compound transport K02033,K15581 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.00000000000000000000000000000000000000005581 154.0
HFD2_k127_8182412_0 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000004353 190.0
HFD2_k127_8182412_1 NMT1-like family - - - 0.000000000000000000000000000000002894 139.0
HFD2_k127_8204859_0 exonuclease activity K16899 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004547 458.0
HFD2_k127_8204859_1 Gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 411.0
HFD2_k127_8209992_0 ABC-type nitrate sulfonate bicarbonate transport - - - 0.00000000000000000000000000000000000002088 156.0
HFD2_k127_8209992_1 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000003832 119.0
HFD2_k127_8209992_2 aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K20448 - 1.17.1.5 0.00007233 49.0
HFD2_k127_8209992_3 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 0.0001651 44.0
HFD2_k127_8229621_0 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 477.0
HFD2_k127_8229621_1 Ornithine cyclodeaminase/mu-crystallin family - - - 0.00000000000000000000000000000000000000000000000004815 186.0
HFD2_k127_8229621_2 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000000000000000000000000000000001812 189.0
HFD2_k127_8229621_3 NMT1-like family - - - 0.000000000000000000004956 108.0
HFD2_k127_8246043_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 572.0
HFD2_k127_8246043_1 Type IV pilus assembly protein PilM; K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002952 251.0
HFD2_k127_8246043_2 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000002283 181.0
HFD2_k127_8246043_3 PFAM helix-turn-helix domain protein - - - 0.00000000000000000114 87.0
HFD2_k127_8246043_4 Fimbrial assembly protein (PilN) K02663 - - 0.000000000000000004328 91.0
HFD2_k127_8246043_5 Pilus assembly protein, PilO K02664 - - 0.000000001061 64.0
HFD2_k127_8249509_0 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 552.0
HFD2_k127_8249509_1 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005168 426.0
HFD2_k127_8249509_2 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652,K03852 - 2.2.1.6,2.3.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007789 303.0
HFD2_k127_8249509_3 Putative cyclase K14250 - - 0.0000000000000000000000000000000000000000000000000000005248 212.0
HFD2_k127_8249509_4 Putative cyclase - - - 0.000000000000000000000000000000000000000000000009123 190.0
HFD2_k127_8249509_5 TIGRFAM ABC transporter, substrate-binding protein, aliphatic K02051 - - 0.0000000000007688 79.0
HFD2_k127_8249509_6 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.000000002917 68.0
HFD2_k127_8249509_7 Removes 5-oxoproline from various penultimate amino acid residues except L-proline K01304 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:1901564 3.4.19.3 0.000000008484 63.0
HFD2_k127_8249509_8 Cupin domain K11312 - - 0.0000008948 51.0
HFD2_k127_8249509_9 PFAM TM2 domain containing protein - - - 0.000002193 56.0
HFD2_k127_8273365_0 ATP dependent DNA ligase domain protein K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 625.0
HFD2_k127_8273365_1 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007249 559.0
HFD2_k127_8273365_2 Polysaccharide pyruvyl transferase - - - 0.00000000000000000000000000000000001886 138.0
HFD2_k127_8274223_0 Malate/L-lactate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 550.0
HFD2_k127_8274223_1 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006496 349.0
HFD2_k127_8274223_2 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000009386 215.0
HFD2_k127_8274223_3 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000001035 213.0
HFD2_k127_8274223_4 Isochorismatase family - - - 0.000000000000005081 79.0
HFD2_k127_8274223_5 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000002012 59.0
HFD2_k127_8279942_0 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000001035 193.0
HFD2_k127_8279942_1 Iron-containing alcohol dehydrogenase K00217 - 1.3.1.32 0.000000000000000000000000000000000000000000000000658 190.0
HFD2_k127_8279942_2 Conserved carboxylase domain K01571 - 4.1.1.3 0.0000000000000000000000000000000000000001354 156.0
HFD2_k127_8279942_3 TIGRFAM acetylornithine deacetylase or succinyl- diaminopimelate desuccinylase K01439 - 3.5.1.18 0.000000000000000000000009563 113.0
HFD2_k127_8294241_0 Heat shock 70 kDa protein K04043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 578.0
HFD2_k127_8294241_1 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007322 558.0
HFD2_k127_8294241_10 - - - - 0.000000000000001539 81.0
HFD2_k127_8294241_11 Bacterial protein of unknown function (DUF883) - - - 0.0000000000000211 77.0
HFD2_k127_8294241_12 Protein involved in outer membrane biogenesis - - - 0.00000000000009435 75.0
HFD2_k127_8294241_13 ZIP Zinc transporter - - - 0.0000000000008209 72.0
HFD2_k127_8294241_14 ABC-type transport auxiliary lipoprotein component K18480 - - 0.000000000005396 69.0
HFD2_k127_8294241_2 UPF0761 membrane protein K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 514.0
HFD2_k127_8294241_3 PFAM Mechanosensitive ion channel K03442 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008886 385.0
HFD2_k127_8294241_4 Protein of unknown function (DUF1614) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000295 248.0
HFD2_k127_8294241_5 ZIP Zinc transporter - - - 0.000000000000000000000000000000000000000000001186 175.0
HFD2_k127_8294241_6 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000000001303 158.0
HFD2_k127_8294241_7 Belongs to the glycosyl hydrolase 13 family - - - 0.000000000000000000000000000000007608 130.0
HFD2_k127_8294241_8 Protein involved in outer membrane biogenesis - - - 0.0000000000000000000005121 100.0
HFD2_k127_8294241_9 - - - - 0.000000000000001152 86.0
HFD2_k127_8304238_0 Belongs to the UbiD family K03182 - 4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008933 461.0
HFD2_k127_8304238_1 Transferase hexapeptide repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001291 242.0
HFD2_k127_8304238_2 Conserved carboxylase domain K01571 - 4.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000003387 232.0
HFD2_k127_8321878_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 387.0
HFD2_k127_8321878_1 Asparaginase K01424 - 3.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 359.0
HFD2_k127_8321878_2 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000002377 198.0
HFD2_k127_8321878_3 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000001808 143.0
HFD2_k127_8321878_4 PFAM Rhomboid family protein - - - 0.000000000000000000000000000354 123.0
HFD2_k127_8324602_0 CoA-transferase family III K07749 GO:0003674,GO:0003824,GO:0008410,GO:0016740,GO:0016782,GO:0047369 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 477.0
HFD2_k127_8324602_1 Acetolactate synthase K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009095 317.0
HFD2_k127_8324602_2 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000003592 136.0
HFD2_k127_8324602_3 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000000000000008294 131.0
HFD2_k127_8324602_4 Luciferase-like monooxygenase - - - 0.0000000000001176 73.0
HFD2_k127_8324602_5 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000005604 58.0
HFD2_k127_8325791_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 2.575e-290 915.0
HFD2_k127_8325791_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 521.0
HFD2_k127_8325791_2 AAA domain K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009597 420.0
HFD2_k127_8325791_3 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 306.0
HFD2_k127_8325791_4 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000000000000000000000007695 217.0
HFD2_k127_8325791_5 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000001616 180.0
HFD2_k127_8325791_6 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.000000000000000000000000000000005649 135.0
HFD2_k127_8325791_7 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000002762 108.0
HFD2_k127_8325791_8 RecX family K03565 - - 0.0000000000000002084 85.0
HFD2_k127_8334804_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 435.0
HFD2_k127_8334804_1 Transketolase, pyrimidine binding domain K21417 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 331.0
HFD2_k127_8334804_2 Glutathione S-transferase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002009 236.0
HFD2_k127_8334804_3 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000547 138.0
HFD2_k127_8334804_4 Glucose / Sorbosone dehydrogenase - - - 0.0003881 44.0
HFD2_k127_8358676_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 2.751e-195 635.0
HFD2_k127_83683_0 ZIP Zinc transporter K16267 - - 0.00000000000000000000000000000000000000000000000000000000005438 214.0
HFD2_k127_83683_1 Pfam Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000004484 191.0
HFD2_k127_83683_2 Glycosyl transferase family 2 - - - 0.000000000000000000000000000005073 124.0
HFD2_k127_8373867_0 PFAM Glycosyl transferase, group 1 K02844 - - 0.0000000000000000000000000000000000000000000000000000000000001607 226.0
HFD2_k127_8373867_1 Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000002587 140.0
HFD2_k127_8373867_2 Methyltransferase domain - - - 0.0000000000000000002428 96.0
HFD2_k127_8373867_3 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.000000000000006928 85.0
HFD2_k127_8374112_0 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000000000000000000000000001722 205.0
HFD2_k127_8374112_1 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000004209 191.0
HFD2_k127_8374112_2 peptidyl-lysine modification to peptidyl-hypusine - - - 0.00000000000000000000002686 99.0
HFD2_k127_8384008_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 1.171e-259 812.0
HFD2_k127_8384008_1 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000004568 64.0
HFD2_k127_8394042_0 AMP-binding enzyme C-terminal domain K02363 - 2.7.7.58,6.3.2.14 3.411e-228 718.0
HFD2_k127_8394042_1 KR domain K00059 - 1.1.1.100 0.000000000000002474 76.0
HFD2_k127_8394042_2 Substrate binding domain of ABC-type glycine betaine transport system - - - 0.00000000005932 74.0
HFD2_k127_8400_0 hydrolase of the alpha beta-hydrolase fold K07020 - - 0.00000000000000000000000000000000000000000000000000000000000000004684 229.0
HFD2_k127_8400_1 - - - - 0.0000000000000000000000000000000000000000000000000000001113 195.0
HFD2_k127_8400_10 ORF located using Blastx - - - 0.00000000000007372 71.0
HFD2_k127_8400_11 - - - - 0.0000000000006116 68.0
HFD2_k127_8400_15 - - - - 0.000003923 56.0
HFD2_k127_8400_2 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.0000000000000000000000000000006758 131.0
HFD2_k127_8400_3 non supervised orthologous group - - - 0.00000000000000000000000005832 108.0
HFD2_k127_8400_4 COG NOG15344 non supervised orthologous group - - - 0.00000000000000000000000117 104.0
HFD2_k127_8400_5 - - - - 0.000000000000000000000716 96.0
HFD2_k127_8400_6 - - - - 0.000000000000000009116 85.0
HFD2_k127_8400_8 Bacterial regulatory proteins, tetR family - - - 0.000000000000000261 87.0
HFD2_k127_8404227_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335,K18331 - 1.12.1.3,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 518.0
HFD2_k127_8404227_1 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000002039 115.0
HFD2_k127_8433853_0 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 464.0
HFD2_k127_8433853_1 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008676 360.0
HFD2_k127_8433853_2 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000003443 230.0
HFD2_k127_8433853_3 - - - - 0.0000000000000000000000000000000000000000000002931 177.0
HFD2_k127_8433853_4 PFAM Acyl-CoA dehydrogenase K16173 - 1.3.99.32 0.00007884 45.0
HFD2_k127_84789_0 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000009913 189.0
HFD2_k127_84789_1 associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000006989 164.0
HFD2_k127_84789_2 Belongs to the ompA family - - - 0.000000000000000000000006075 111.0
HFD2_k127_84789_4 Belongs to the ompA family - - - 0.0002151 49.0
HFD2_k127_8496612_0 Helix-hairpin-helix containing domain K03581 - 3.1.11.5 3.465e-214 688.0
HFD2_k127_8496612_1 Transporter associated domain K03699,K06189 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 427.0
HFD2_k127_8496612_2 lactoylglutathione lyase activity - - - 0.0000000000001445 71.0
HFD2_k127_8498542_0 MmgE/PrpD family K01720 - 4.2.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 379.0
HFD2_k127_8498542_1 Belongs to the TPP enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 377.0
HFD2_k127_8498542_2 Cobalamin-independent synthase, Catalytic domain K00549,K22363 - 2.1.1.14,4.4.1.23 0.000000000000000000000000000000000000000000000000000000000000009508 230.0
HFD2_k127_8498542_3 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.0000000000002516 81.0
HFD2_k127_8498542_4 thiamine-containing compound biosynthetic process K02050,K02051 - - 0.0000001017 63.0
HFD2_k127_8515455_0 ATP-grasp domain K01905,K22224 - 6.2.1.13 8.467e-320 1002.0
HFD2_k127_8530747_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005077 286.0
HFD2_k127_8530747_1 Putative MetA-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000002579 216.0
HFD2_k127_8530747_2 phosphonopyruvate decarboxylase K09459 - 4.1.1.82 0.00000000004885 70.0
HFD2_k127_8530747_3 Belongs to the TPP enzyme family K13039 - 4.1.1.79 0.0000000001172 68.0
HFD2_k127_8530747_4 alcohol dehydrogenase K00121 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0009268,GO:0009628,GO:0010447,GO:0030312,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051704,GO:0071944 1.1.1.1,1.1.1.284 0.000003242 53.0
HFD2_k127_854413_0 type IV pilus modification protein PilV K02671 - - 0.0000283 51.0
HFD2_k127_854413_1 Type IV Pilus-assembly protein W K02672 - - 0.00004097 53.0
HFD2_k127_8548313_0 PFAM FAD linked oxidase domain protein - - - 3.056e-245 777.0
HFD2_k127_8549835_0 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009983 385.0
HFD2_k127_8549835_1 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000005437 231.0
HFD2_k127_8549835_2 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000000000002069 204.0
HFD2_k127_8549835_3 thiamine biosynthesis protein ThiS K03154 - - 0.00000000000001168 76.0
HFD2_k127_8606519_0 lactate metabolic process K00113 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0045333,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000001283 226.0
HFD2_k127_8606519_1 the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000004476 226.0
HFD2_k127_8606519_2 Ferric uptake regulator family K03711,K09825 - - 0.00000000000000000000000000000000000000002539 160.0
HFD2_k127_8606519_3 Conserved hypothetical protein (Lin0512_fam) - - - 0.0000000000000000000000000000000000000006941 150.0
HFD2_k127_8606519_4 - - - - 0.000000309 55.0
HFD2_k127_8606519_5 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.000958 45.0
HFD2_k127_8623127_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000004208 258.0
HFD2_k127_8623127_1 Rubrerythrin - - - 0.000000000000749 76.0
HFD2_k127_8623127_2 Dienelactone hydrolase family - - - 0.00000000002023 65.0
HFD2_k127_8632208_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.809e-251 790.0
HFD2_k127_8632208_1 ribosomal large subunit export from nucleus - - - 0.00000000000000000000000000004083 127.0
HFD2_k127_8632208_2 Transcription factor zinc-finger K09981 - - 0.0000003988 56.0
HFD2_k127_8635660_0 Sulfite reductase K00366,K00381,K00392 - 1.7.7.1,1.8.1.2,1.8.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 497.0
HFD2_k127_8635660_1 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.0000000000000000000000000000000000000000000000000000000009168 205.0
HFD2_k127_8635660_2 - - - - 0.0000000000000000003063 99.0
HFD2_k127_8726000_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 5.581e-219 692.0
HFD2_k127_8726000_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000859 313.0
HFD2_k127_8726000_2 MnmE helical domain K03650 - - 0.00000000000000000000000000000000000000000000000000006717 192.0
HFD2_k127_8726000_3 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000000001114 75.0
HFD2_k127_8726000_4 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031974,GO:0031981,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.00000000005904 68.0
HFD2_k127_8726552_0 DinB superfamily K18912 - 1.14.99.50 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 383.0
HFD2_k127_8726552_1 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005162 323.0
HFD2_k127_8726552_10 Redoxin K03564 - 1.11.1.15 0.0000000000000007169 78.0
HFD2_k127_8726552_11 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000000005151 75.0
HFD2_k127_8726552_2 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002669 238.0
HFD2_k127_8726552_3 The glycine cleavage system catalyzes the degradation of glycine K00605,K06980,K22086 - 1.5.99.5,2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000008413 229.0
HFD2_k127_8726552_4 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000002874 218.0
HFD2_k127_8726552_5 NUDIX domain K00077,K01092,K03574,K03795 - 1.1.1.169,3.1.3.25,3.6.1.55,4.99.1.3 0.00000000000000000000000000000000000000000000000000000000002738 210.0
HFD2_k127_8726552_6 Redoxin K03564 - 1.11.1.15 0.0000000000000000000000000000000000000008403 151.0
HFD2_k127_8726552_7 Domain of unknown function (DUF427) - - - 0.00000000000000000000000000000000000006203 150.0
HFD2_k127_8726552_8 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000009122 126.0
HFD2_k127_8726552_9 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00363,K05710 - 1.7.1.15 0.000000000000000000000000001006 115.0
HFD2_k127_8733361_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004244 483.0
HFD2_k127_8733361_1 Conserved carboxylase domain K01571 - 4.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004219 395.0
HFD2_k127_8733361_2 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001061 280.0
HFD2_k127_8733361_3 proline dipeptidase activity K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000004591 254.0
HFD2_k127_8733361_4 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000007942 179.0
HFD2_k127_8733361_5 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000003653 147.0
HFD2_k127_8733361_6 PFAM OmpA MotB domain protein K03640 - - 0.000000000000000000000000000000009313 134.0
HFD2_k127_8733361_7 Conserved carboxylase domain - - - 0.00000000000000000000006937 102.0
HFD2_k127_8733361_8 VanZ like family - - - 0.0000000000000000000001102 105.0
HFD2_k127_885434_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 2.086e-279 879.0
HFD2_k127_885434_1 CO dehydrogenase flavoprotein domain protein K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001259 287.0
HFD2_k127_885434_2 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000001225 239.0
HFD2_k127_885434_3 PFAM carbon monoxide dehydrogenase subunit G K09386 - - 0.000000000000001512 82.0
HFD2_k127_886117_0 Binding-protein-dependent transport system inner membrane component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004323 493.0
HFD2_k127_886117_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K02052 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006588 377.0
HFD2_k127_886117_2 4,5-dihydroxyphthalate decarboxylase K04102 - 4.1.1.55 0.000000000000000000000000000000000000000000004464 168.0
HFD2_k127_886117_3 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141,K19190 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019538,GO:0019637,GO:0019720,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061602,GO:0070567,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902759,GO:1902760 1.1.1.328,2.7.7.76 0.000000000000000000000000000000005441 135.0
HFD2_k127_886117_4 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000000000000001797 139.0
HFD2_k127_88697_0 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005242 443.0
HFD2_k127_88697_1 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000004641 134.0
HFD2_k127_88697_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000004604 91.0
HFD2_k127_88697_3 iron ion homeostasis K02012 - - 0.0000003125 60.0
HFD2_k127_889430_0 Tripartite tricarboxylate transporter TctA family K07793 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001363 281.0
HFD2_k127_889430_1 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.0000000000000000000000001704 106.0
HFD2_k127_889430_2 Tripartite tricarboxylate transporter TctB family K07794 - - 0.000000007271 63.0
HFD2_k127_892385_0 PFAM FAD linked oxidase domain protein K00102,K00104 - 1.1.2.4,1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003555 517.0
HFD2_k127_892385_1 4Fe-4S dicluster domain K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 418.0
HFD2_k127_892385_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 366.0
HFD2_k127_892385_3 PFAM FAD linked oxidase domain protein K11472 - - 0.0000000000000000000000000000000000000000000000000000000000000000003926 245.0
HFD2_k127_90254_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006288 392.0
HFD2_k127_90254_1 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 307.0
HFD2_k127_90254_2 Pfam:DUF59 K02612 - - 0.00000000000000000000000000000000001413 137.0
HFD2_k127_90254_3 toxin-antitoxin pair type II binding - - - 0.000000000003081 69.0
HFD2_k127_90254_4 Protein conserved in bacteria K18480 - - 0.0000000002599 63.0
HFD2_k127_904572_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 5.329e-205 643.0
HFD2_k127_904572_1 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000002363 123.0
HFD2_k127_916898_0 Bacterial regulatory protein, Fis family K10941 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 304.0
HFD2_k127_916898_1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.000000000000000000000001419 109.0
HFD2_k127_916898_2 Acetamidase/Formamidase family - - - 0.000002141 53.0
HFD2_k127_91912_0 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs K00087,K03519 - 1.17.1.4,1.2.5.3 0.00000000000000000000000000000000000000000000000000001607 199.0
HFD2_k127_91912_1 Binding-protein-dependent transport system inner membrane component K02011,K02063 - - 0.0000000000000000000000000000000000000000000000002473 182.0
HFD2_k127_91912_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000004991 64.0
HFD2_k127_925110_0 Binding-protein-dependent transport system inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 466.0
HFD2_k127_925110_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 424.0
HFD2_k127_925110_2 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001307 279.0
HFD2_k127_925110_3 - - - - 0.00000000000000000005467 102.0
HFD2_k127_925110_4 - - - - 0.00000000000000001977 87.0
HFD2_k127_927047_0 nitrogen compound transport K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 350.0
HFD2_k127_927047_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008461 343.0
HFD2_k127_927047_2 Carbon-nitrogen hydrolase K11206 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 314.0
HFD2_k127_927047_3 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000711 289.0
HFD2_k127_927047_4 PFAM Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000004154 171.0
HFD2_k127_927047_5 ornithine cyclodeaminase mu-crystallin K01750 - 4.3.1.12 0.0000000000000000000000000000000000000000000524 173.0
HFD2_k127_927047_6 - - - - 0.00000000000000000000000000000000131 133.0
HFD2_k127_927047_7 Cupin 2, conserved barrel domain protein K21700 - - 0.0000000000000000006866 90.0
HFD2_k127_927047_8 Hemerythrin HHE cation binding domain - - - 0.000000002929 63.0
HFD2_k127_93150_0 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 416.0
HFD2_k127_93150_1 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 313.0
HFD2_k127_93150_2 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000002349 192.0
HFD2_k127_93150_3 MlaC protein K07323 - - 0.0000000000000000000000000000000000000003158 154.0
HFD2_k127_93150_4 Belongs to the glutaminase family K01425 - 3.5.1.2 0.000000007406 66.0
HFD2_k127_944720_0 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007491 471.0
HFD2_k127_944720_1 Cytochrome c554 and c-prime K03620 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 294.0
HFD2_k127_944720_2 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.0000000000000000000000000000000000000000000000000000455 192.0
HFD2_k127_957648_0 Isocitrate/isopropylmalate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 552.0
HFD2_k127_957648_1 Protein of unknown function (DUF664) - - - 0.00000000000000000000000000000000001254 142.0
HFD2_k127_957648_2 Phage derived protein Gp49-like (DUF891) - - - 0.00000000000000000000000000000000004148 136.0
HFD2_k127_957648_3 addiction module antidote protein - - - 0.0000000000000000000000000000009402 126.0
HFD2_k127_957648_5 thiamine-containing compound biosynthetic process K02051 - - 0.00001086 54.0
HFD2_k127_960437_0 iron assimilation K07223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006203 373.0
HFD2_k127_965031_0 Belongs to the UbiD family K03182,K16874 - 4.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006837 328.0
HFD2_k127_96695_0 Histidine kinase K07711 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000025 203.0
HFD2_k127_96695_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000001525 188.0
HFD2_k127_96695_2 Belongs to the 'phage' integrase family - - - 0.000000000000000001718 96.0
HFD2_k127_96695_3 PFAM Phage Terminase - - - 0.00000261 58.0
HFD2_k127_967400_0 ethanolamine utilization protein K04019 GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0030091,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009,GO:0071704,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 575.0
HFD2_k127_967400_3 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000013 140.0
HFD2_k127_967400_4 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000005639 106.0
HFD2_k127_969252_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 7.816e-282 876.0
HFD2_k127_969252_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006258 564.0
HFD2_k127_969252_2 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007139 294.0
HFD2_k127_969252_3 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001909 285.0
HFD2_k127_969252_4 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000001151 279.0
HFD2_k127_969252_5 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.00000000000000000000000000000000000000000000000000000000000000000000001228 250.0
HFD2_k127_969252_6 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000001994 105.0
HFD2_k127_969252_7 YbbR-like protein - - - 0.0000000000000325 83.0
HFD2_k127_983975_0 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000006588 184.0
HFD2_k127_983975_1 Biopolymer transport protein K03559 - - 0.00000000000002892 77.0
HFD2_k127_983975_2 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000002439 51.0
HFD2_k127_983975_3 von Willebrand factor, type A - - - 0.0000124 57.0
HFD2_k127_985398_0 SMART Elongator protein 3 MiaB NifB K07139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003724 324.0
HFD2_k127_985398_1 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000000000000000000000002054 164.0
HFD2_k127_985398_2 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000004798 109.0
HFD2_k127_985398_3 Thioesterase-like superfamily K07107 - - 0.00000000000005077 73.0
HFD2_k127_989767_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000063 461.0
HFD2_k127_989767_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005475 424.0
HFD2_k127_989767_2 Carotenoid biosynthesis protein K22502 - 5.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000822 288.0
HFD2_k127_989767_3 imidazolonepropionase activity - - - 0.000000000000000000000000000000000000000000000001536 194.0
HFD2_k127_989767_4 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000001122 183.0
HFD2_k127_989767_5 MAPEG family - - - 0.00000000000000000000000000000000000000000008081 163.0
HFD2_k127_989767_6 Fibronectin type 3 domain - - - 0.000000000000000000000000000000000007458 157.0
HFD2_k127_989767_7 COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family - - - 0.0000000000000000000787 99.0
HFD2_k127_992115_0 Belongs to the GMC oxidoreductase family K00108 - 1.1.99.1 0.0000000000000000000000000000000000000000000000000000000000000000001983 246.0
HFD2_k127_992115_1 PFAM carbon monoxide dehydrogenase subunit G K09386 - - 0.0000000000000005779 83.0
HFD2_k127_995404_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 441.0
HFD2_k127_995404_1 SecD/SecF GG Motif K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004912 289.0
HFD2_k127_995404_2 PFAM phosphoesterase, RecJ domain protein K07462 - - 0.000000000000000000000000000004986 123.0
HFD2_k127_995888_0 Thiamine pyrophosphate enzyme, central domain - - - 1.021e-242 762.0
HFD2_k127_995888_1 Thiamine pyrophosphate enzyme, central domain - - - 4.975e-237 746.0
HFD2_k127_995888_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004859 339.0
HFD2_k127_995888_3 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009812 323.0
HFD2_k127_995888_4 - - - - 0.00000000000116 76.0
HFD2_k127_995888_5 NMT1-like family K02051,K15551 - - 0.000000000009228 77.0