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Overview

ID MAG01668
Name HFD2_bin.65
Sample SMP0044
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Vicinamibacteria
Order Fen-336
Family Fen-336
Genus JAICEW01
Species
Assembly information
Completeness (%) 89.37
Contamination (%) 4.02
GC content (%) 73.0
N50 (bp) 24,321
Genome size (bp) 4,821,772

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3836

Gene name Description KEGG GOs EC E-value Score Sequence
HFD2_k127_1013916_0 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 426.0
HFD2_k127_1013916_1 Oligoendopeptidase f - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 418.0
HFD2_k127_1013916_2 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 305.0
HFD2_k127_1013916_3 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000000000000004444 234.0
HFD2_k127_1015584_0 Response regulator receiver - - - 3.339e-206 679.0
HFD2_k127_1015584_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.15 1.328e-194 638.0
HFD2_k127_1015584_10 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004636 364.0
HFD2_k127_1015584_11 Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor) K17763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005135 348.0
HFD2_k127_1015584_12 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 326.0
HFD2_k127_1015584_13 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006455 306.0
HFD2_k127_1015584_14 SMART Tetratricopeptide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006476 331.0
HFD2_k127_1015584_15 PFAM Band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 311.0
HFD2_k127_1015584_16 Sigma factor PP2C-like phosphatases K05518 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006797 289.0
HFD2_k127_1015584_17 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000001602 248.0
HFD2_k127_1015584_18 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.00000000000000000000000000000000000000000000000000000000002957 214.0
HFD2_k127_1015584_19 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02236,K02278,K02506,K02654,K10966 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000006347 215.0
HFD2_k127_1015584_2 cyclic 2,3-diphosphoglycerate synthetase activity K05716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004529 602.0
HFD2_k127_1015584_20 Histidine kinase-like ATPase domain K17752 - 2.7.11.1 0.000000000000000000000000000000000000000000000000004759 185.0
HFD2_k127_1015584_21 STAS domain K17762 - - 0.000000000000000000000000000000000000000000001821 176.0
HFD2_k127_1015584_22 - - - - 0.00000000000000000000000000000000000000000002091 165.0
HFD2_k127_1015584_23 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000000000000000502 180.0
HFD2_k127_1015584_24 Evidence 5 No homology to any previously reported sequences K09005 - - 0.00000000000000000000000000001596 124.0
HFD2_k127_1015584_25 Predicted membrane protein (DUF2339) - - - 0.000000000000000000000000005756 129.0
HFD2_k127_1015584_26 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000009485 103.0
HFD2_k127_1015584_27 - - - - 0.0000000000000000002784 103.0
HFD2_k127_1015584_28 Heat shock protein DnaJ domain protein - - - 0.00000000000000002716 94.0
HFD2_k127_1015584_29 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.0000000000003735 85.0
HFD2_k127_1015584_3 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004634 488.0
HFD2_k127_1015584_30 Tetratricopeptide repeat - - - 0.000000000009713 77.0
HFD2_k127_1015584_31 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117,K03646 - - 0.00000000002783 74.0
HFD2_k127_1015584_32 pilus assembly protein PilW K02672 - - 0.00002841 57.0
HFD2_k127_1015584_33 Prepilin K08084 - - 0.00009244 52.0
HFD2_k127_1015584_4 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007453 468.0
HFD2_k127_1015584_5 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002701 446.0
HFD2_k127_1015584_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 443.0
HFD2_k127_1015584_7 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 391.0
HFD2_k127_1015584_8 membrane protein, TerC K05794 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003857 392.0
HFD2_k127_1015584_9 Sodium/calcium exchanger protein K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007352 366.0
HFD2_k127_1045123_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.05e-269 876.0
HFD2_k127_1045123_1 ATPases associated with a variety of cellular activities K01990,K09689,K09691,K09693 - 3.6.3.38,3.6.3.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006773 462.0
HFD2_k127_1045123_10 PPIC-type PPIASE domain K01802,K03769 - 5.2.1.8 0.0000000000005984 79.0
HFD2_k127_1045123_11 outer membrane autotransporter barrel domain protein - - - 0.000000277 63.0
HFD2_k127_1045123_2 ABC-2 type transporter K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005242 254.0
HFD2_k127_1045123_3 PFAM RNA-binding protein AU-1 Ribonuclease E G K08301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007469 241.0
HFD2_k127_1045123_4 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.0000000000000000000000000000000000000000000000000002081 190.0
HFD2_k127_1045123_5 SurA N-terminal domain K03771 - 5.2.1.8 0.00000000000000000000000000003399 130.0
HFD2_k127_1045123_6 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000001055 121.0
HFD2_k127_1045123_7 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.000000000000000000000000000833 113.0
HFD2_k127_1045123_8 Domain of unknown function (DUF4388) - - - 0.000000000000000002162 100.0
HFD2_k127_1045123_9 methylated DNA-protein cysteine methyltransferase K07443 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363 - 0.000000000000000044 94.0
HFD2_k127_109091_0 MacB-like periplasmic core domain - - - 5.705e-314 981.0
HFD2_k127_109091_1 glutamine synthetase K01915 - 6.3.1.2 5.37e-208 682.0
HFD2_k127_109091_10 (ABC) transporter K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009602 413.0
HFD2_k127_109091_11 inositol monophosphate 1-phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006728 427.0
HFD2_k127_109091_12 Two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005592 403.0
HFD2_k127_109091_13 ABC 3 transport family K02075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007831 372.0
HFD2_k127_109091_14 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 365.0
HFD2_k127_109091_15 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006451 313.0
HFD2_k127_109091_16 FAD dependent oxidoreductase K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 310.0
HFD2_k127_109091_17 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000005807 229.0
HFD2_k127_109091_18 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000005227 143.0
HFD2_k127_109091_19 GAF domain - - - 0.0000000000000000000000000009531 131.0
HFD2_k127_109091_2 Involved in the tonB-independent uptake of proteins - - - 3.251e-198 661.0
HFD2_k127_109091_20 Cupredoxin-like domain - - - 0.0000005346 59.0
HFD2_k127_109091_3 5'-nucleotidase, C-terminal domain K11751 - 3.1.3.5,3.6.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 517.0
HFD2_k127_109091_4 TIGRFAM galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007035 484.0
HFD2_k127_109091_5 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10441 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007844 484.0
HFD2_k127_109091_6 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 451.0
HFD2_k127_109091_7 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 443.0
HFD2_k127_109091_8 Belongs to the binding-protein-dependent transport system permease family K02057,K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 449.0
HFD2_k127_109091_9 Zinc-uptake complex component A periplasmic K02077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000706 418.0
HFD2_k127_1093735_0 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000012 246.0
HFD2_k127_1093735_1 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.0000000000000000000000000000000000003334 152.0
HFD2_k127_1145078_0 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004409 471.0
HFD2_k127_1145078_1 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000005376 216.0
HFD2_k127_1145078_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000001872 143.0
HFD2_k127_1145078_3 Radical SAM domain protein - - - 0.000000000001235 81.0
HFD2_k127_1158429_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.08e-268 848.0
HFD2_k127_1158429_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 317.0
HFD2_k127_1158429_2 Zn-dependent dipeptidase, microsomal dipeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 334.0
HFD2_k127_1158429_3 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000005902 241.0
HFD2_k127_1158429_4 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000009811 194.0
HFD2_k127_1158429_5 Methyltransferase small domain - - - 0.00000000000000000000001192 116.0
HFD2_k127_1158429_6 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.0000000000000004065 83.0
HFD2_k127_1161974_0 Flavin containing amine oxidoreductase - - - 9.288e-258 825.0
HFD2_k127_1161974_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007596 562.0
HFD2_k127_1161974_2 TIGRFAM phytoene desaturase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000495 490.0
HFD2_k127_1161974_3 peptidyl-lysine modification to peptidyl-hypusine K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 454.0
HFD2_k127_1161974_4 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000000000000000000000000000000000000000000000000000008179 255.0
HFD2_k127_1161974_5 Protein of unknown function (DUF2400) K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000001444 239.0
HFD2_k127_1161974_6 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000004443 147.0
HFD2_k127_1220009_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 526.0
HFD2_k127_1220009_1 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005206 389.0
HFD2_k127_1220009_2 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001488 273.0
HFD2_k127_1220009_3 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000006891 194.0
HFD2_k127_1220009_4 Uncharacterized protein conserved in bacteria (DUF2199) - - - 0.0000000000000000000000000000008646 130.0
HFD2_k127_1220009_5 domain, Protein - - - 0.0000000000000003989 90.0
HFD2_k127_1271797_0 DNA polymerase K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0 1143.0
HFD2_k127_1271797_1 Glutamine synthetase K01915 - 6.3.1.2 3.157e-250 779.0
HFD2_k127_1271797_10 SCO1/SenC K07152,K08976 - - 0.0000000000000000000000000000000000000000000002853 172.0
HFD2_k127_1271797_11 cytochrome oxidase assembly K02259 - - 0.0000000000000000000000000000000000000000000006297 179.0
HFD2_k127_1271797_12 cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000002499 158.0
HFD2_k127_1271797_13 protein SCO1 SenC K07152 - - 0.000000000000000000000000000001511 132.0
HFD2_k127_1271797_14 COG1520 FOG WD40-like repeat - - - 0.000000000000005075 87.0
HFD2_k127_1271797_2 Belongs to the heme-copper respiratory oxidase family K02274 - 1.9.3.1 1.227e-201 646.0
HFD2_k127_1271797_3 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 8.28e-198 628.0
HFD2_k127_1271797_4 PFAM Aminotransferase class I and II K05825 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007406 325.0
HFD2_k127_1271797_5 Cellulase N-terminal ig-like domain K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000003857 292.0
HFD2_k127_1271797_6 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000097 256.0
HFD2_k127_1271797_7 COGs COG1622 Heme copper-type cytochrome quinol oxidase subunit 2 K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000008416 214.0
HFD2_k127_1271797_8 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000003558 209.0
HFD2_k127_1271797_9 Polysaccharide lyase family 4, domain II - - - 0.000000000000000000000000000000000000000000000002624 195.0
HFD2_k127_1273158_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004343 440.0
HFD2_k127_1273158_1 PFAM iron dependent repressor K03709 - - 0.00000000000000000000000000000000000000000000001512 181.0
HFD2_k127_1273158_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000001648 123.0
HFD2_k127_1273158_3 FeoA K04758 - - 0.0000009238 61.0
HFD2_k127_1285784_0 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 5.555e-232 732.0
HFD2_k127_1285784_1 PFAM Type II secretion system protein E K02652 - - 3.217e-224 716.0
HFD2_k127_1285784_10 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000001358 155.0
HFD2_k127_1285784_11 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.00000000000000000000000000000000000000216 164.0
HFD2_k127_1285784_12 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit K07315 - 3.1.3.3 0.0000000000000000000000000000000000000101 163.0
HFD2_k127_1285784_13 Prokaryotic N-terminal methylation motif K02456 - - 0.00000000000000000000000000000000000008369 158.0
HFD2_k127_1285784_14 Peptidase family M54 K06974 - - 0.0000000000000000000000000000000000006454 153.0
HFD2_k127_1285784_15 Pfam:N_methyl_2 K02456 - - 0.000000000000000000000000000000003941 132.0
HFD2_k127_1285784_16 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000349 131.0
HFD2_k127_1285784_17 Pilus assembly protein K02662 - - 0.0000000000000000001365 100.0
HFD2_k127_1285784_18 oligosaccharyl transferase activity - - - 0.00000000000003607 86.0
HFD2_k127_1285784_19 general secretion pathway protein K02456,K02650 - - 0.00000000004473 75.0
HFD2_k127_1285784_2 phosphorelay signal transduction system K02481,K07713,K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 528.0
HFD2_k127_1285784_20 - K02664 - - 0.0000003636 63.0
HFD2_k127_1285784_21 PFAM Fimbrial assembly family protein K02663 - - 0.00003456 57.0
HFD2_k127_1285784_3 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 329.0
HFD2_k127_1285784_4 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004076 302.0
HFD2_k127_1285784_5 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004481 287.0
HFD2_k127_1285784_6 PFAM Type II secretion system F domain K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004722 264.0
HFD2_k127_1285784_7 Pyridoxal phosphate biosynthetic protein PdxA K00097 - 1.1.1.262 0.00000000000000000000000000000000000000000000000000000000000000000000000007854 262.0
HFD2_k127_1285784_8 Belongs to the GSP D family K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003632 275.0
HFD2_k127_1285784_9 Histidine kinase K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000001151 243.0
HFD2_k127_1293631_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 6.303e-282 891.0
HFD2_k127_1293631_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 535.0
HFD2_k127_1293631_2 Large family of predicted nucleotide-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005224 358.0
HFD2_k127_1293631_3 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004297 305.0
HFD2_k127_1293631_4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001141 273.0
HFD2_k127_1293631_5 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001484 276.0
HFD2_k127_1293631_6 UvrD/REP helicase N-terminal domain K03657,K07465 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000001014 233.0
HFD2_k127_1293631_7 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.00000000000000000000000000000000005371 156.0
HFD2_k127_1293631_8 B3/4 domain - - - 0.00000000000000000000000000000009202 144.0
HFD2_k127_1293631_9 Sulfatase-modifying factor enzyme 1 - - - 0.000000578 56.0
HFD2_k127_131204_0 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005411 297.0
HFD2_k127_131204_1 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001044 285.0
HFD2_k127_131641_0 Methyltransferase type 11 K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000001203 199.0
HFD2_k127_131641_1 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000000000000000289 124.0
HFD2_k127_131641_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000008225 102.0
HFD2_k127_131641_3 Transmembrane secretion effector - - - 0.0000000000000000003027 100.0
HFD2_k127_1404586_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1071.0
HFD2_k127_1404586_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 2.991e-277 859.0
HFD2_k127_1404586_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585,K07799 - - 0.0000000000000000000000000000000000000000000000000002256 199.0
HFD2_k127_1404586_11 tRNA methyltransferase complex GCD14 subunit - - - 0.00000000000000000000000000000000000000000000002021 178.0
HFD2_k127_1404586_12 amine dehydrogenase activity K20276 - - 0.0000000000000000000000000000000000007397 158.0
HFD2_k127_1404586_13 - - - - 0.000000000000000000000000000000009361 143.0
HFD2_k127_1404586_14 - - - - 0.000000000000000000000005683 119.0
HFD2_k127_1404586_16 Periplasmic copper-binding protein (NosD) - - - 0.0006192 51.0
HFD2_k127_1404586_2 CoA enzyme activase uncharacterised domain (DUF2229) - - - 7.462e-276 879.0
HFD2_k127_1404586_3 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004227 509.0
HFD2_k127_1404586_4 lysine biosynthetic process via aminoadipic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 360.0
HFD2_k127_1404586_5 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 294.0
HFD2_k127_1404586_6 BadF BadG BcrA BcrD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002465 294.0
HFD2_k127_1404586_7 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008281 283.0
HFD2_k127_1404586_8 PFAM Chlorite dismutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001465 274.0
HFD2_k127_1404586_9 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000000000000000000000000000000000001177 213.0
HFD2_k127_1437931_0 Acetyl-CoA carboxylase, central region - - - 0.0 1864.0
HFD2_k127_1437931_1 PFAM short-chain dehydrogenase reductase SDR K15314 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 512.0
HFD2_k127_1437931_10 von Willebrand factor, type A - - - 0.000000000000000000000000000000000003275 153.0
HFD2_k127_1437931_11 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000008776 132.0
HFD2_k127_1437931_12 4'-phosphopantetheinyl transferase superfamily K06133 - - 0.00000000000000000000003333 116.0
HFD2_k127_1437931_13 Protein of unknown function DUF84 - GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0017144,GO:0034641,GO:0042723,GO:0044237,GO:0044281,GO:0046483,GO:0071704,GO:0072527,GO:1901360,GO:1901564 - 0.000000000000000306 93.0
HFD2_k127_1437931_14 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.000000000000000709 87.0
HFD2_k127_1437931_15 Chalcone isomerase-like - - - 0.000000000000003341 83.0
HFD2_k127_1437931_16 peptidyl-tyrosine sulfation - - - 0.0000000003965 72.0
HFD2_k127_1437931_17 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.000000005426 65.0
HFD2_k127_1437931_18 - - - - 0.00001086 54.0
HFD2_k127_1437931_19 Tetratricopeptide repeat protein - - - 0.00007189 53.0
HFD2_k127_1437931_2 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006638 443.0
HFD2_k127_1437931_3 Similarity to COG0471 Di- and tricarboxylate transporters(Evalue K14445 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 374.0
HFD2_k127_1437931_4 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003786 242.0
HFD2_k127_1437931_5 Thymidine kinase K00857 - 2.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000009276 233.0
HFD2_k127_1437931_6 GHMP kinases C terminal K07031 - 2.7.1.168 0.000000000000000000000000000000000000000000000000000000004962 213.0
HFD2_k127_1437931_7 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000004876 197.0
HFD2_k127_1437931_8 PFAM membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.0000000000000000000000000000000000000000000000000007547 205.0
HFD2_k127_1437931_9 lipase activity K15349 - - 0.0000000000000000000000000000000000000000000001375 193.0
HFD2_k127_1524525_0 serine-type peptidase activity K01990,K08884,K12132,K18912 - 1.14.99.50,2.7.11.1 7.787e-259 832.0
HFD2_k127_1524525_1 Lamin Tail Domain K07004 - - 5.06e-199 677.0
HFD2_k127_1524525_10 - - - - 0.0000000000000000000000000000000000000000000000000000001572 200.0
HFD2_k127_1524525_11 helix_turn_helix gluconate operon transcriptional repressor K07979 - - 0.0000000000000000000000000000000000000000000000002862 178.0
HFD2_k127_1524525_12 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000002997 176.0
HFD2_k127_1524525_13 PFAM Sulfatase - - - 0.00000000000000000000000000000000000000001959 175.0
HFD2_k127_1524525_14 6-phosphogluconolactonase activity K20276 - - 0.00000000000000000000000000000000000009808 166.0
HFD2_k127_1524525_15 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.0000000000000000000000000000000002935 134.0
HFD2_k127_1524525_16 Protein involved in meta-pathway of phenol degradation - - - 0.00000000000000000000002448 113.0
HFD2_k127_1524525_18 Lamin Tail Domain K07004 - - 0.0006584 46.0
HFD2_k127_1524525_2 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 443.0
HFD2_k127_1524525_3 Arylsulfotransferase (ASST) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006389 366.0
HFD2_k127_1524525_4 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K19802 - 5.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008401 347.0
HFD2_k127_1524525_5 - K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 311.0
HFD2_k127_1524525_6 Protein of unknown function (DUF819) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009809 306.0
HFD2_k127_1524525_7 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002429 260.0
HFD2_k127_1524525_8 phosphatase K01083,K07004 - 3.1.3.8 0.000000000000000000000000000000000000000000000000000000000000009496 248.0
HFD2_k127_1524525_9 NlpC/P60 family - - - 0.0000000000000000000000000000000000000000000000000000000007708 216.0
HFD2_k127_163457_0 Carboxypeptidase regulatory-like domain - - - 2.824e-320 1013.0
HFD2_k127_163457_1 - - - - 0.00000000004243 78.0
HFD2_k127_1638364_0 efflux transmembrane transporter activity - - - 1.845e-274 874.0
HFD2_k127_1638364_1 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 2.015e-263 856.0
HFD2_k127_1638364_10 N-acetylglucosaminylinositol deacetylase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 300.0
HFD2_k127_1638364_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001805 286.0
HFD2_k127_1638364_12 Short-chain dehydrogenase reductase sdr K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000003816 271.0
HFD2_k127_1638364_13 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004988 259.0
HFD2_k127_1638364_14 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000004067 272.0
HFD2_k127_1638364_15 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000291 224.0
HFD2_k127_1638364_16 Cupin superfamily (DUF985) - - - 0.000000000000000000000000000000000000000000000000001064 188.0
HFD2_k127_1638364_17 nuclear chromosome segregation - - - 0.000000000000000000000000000000000000000000000000002295 208.0
HFD2_k127_1638364_18 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000000000000000000000000002389 169.0
HFD2_k127_1638364_19 Histidine kinase A domain protein K02482 - 2.7.13.3 0.0000000000000000000000000000000001936 152.0
HFD2_k127_1638364_2 phosphatidate phosphatase activity K09474,K19302 - 3.1.3.2,3.6.1.27 2.84e-209 661.0
HFD2_k127_1638364_20 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0000000000000000000000000000001043 140.0
HFD2_k127_1638364_21 Thioredoxin-like - - - 0.0000000000000000000000000000002369 130.0
HFD2_k127_1638364_22 COG0438 Glycosyltransferase - - - 0.00000000000000000000000000001201 124.0
HFD2_k127_1638364_23 long-chain fatty acid transporting porin activity - - - 0.00000000000000000003483 103.0
HFD2_k127_1638364_24 Translation initiation factor SUI1 K03113 - - 0.000000000000001762 81.0
HFD2_k127_1638364_25 Poly (ADP-ribose) polymerase K10798 GO:0000002,GO:0000003,GO:0000122,GO:0000166,GO:0000228,GO:0000302,GO:0000303,GO:0000305,GO:0000715,GO:0000723,GO:0000724,GO:0000725,GO:0000785,GO:0000790,GO:0000791,GO:0000976,GO:0000977,GO:0000981,GO:0001012,GO:0001067,GO:0001228,GO:0001817,GO:0001818,GO:0002009,GO:0002064,GO:0002065,GO:0002066,GO:0002225,GO:0002376,GO:0002520,GO:0002521,GO:0002573,GO:0002682,GO:0002684,GO:0002697,GO:0002699,GO:0002700,GO:0002702,GO:0002759,GO:0002760,GO:0002784,GO:0002786,GO:0002791,GO:0002792,GO:0002803,GO:0002805,GO:0002807,GO:0002808,GO:0002831,GO:0002833,GO:0002920,GO:0002922,GO:0003002,GO:0003006,GO:0003254,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0003690,GO:0003700,GO:0003824,GO:0003909,GO:0003910,GO:0003950,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005654,GO:0005667,GO:0005694,GO:0005700,GO:0005703,GO:0005719,GO:0005730,GO:0005737,GO:0005739,GO:0006139,GO:0006140,GO:0006163,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006282,GO:0006284,GO:0006289,GO:0006293,GO:0006294,GO:0006296,GO:0006302,GO:0006310,GO:0006351,GO:0006355,GO:0006357,GO:0006366,GO:0006464,GO:0006471,GO:0006508,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006950,GO:0006952,GO:0006955,GO:0006963,GO:0006974,GO:0006979,GO:0006996,GO:0006997,GO:0007000,GO:0007005,GO:0007154,GO:0007163,GO:0007165,GO:0007166,GO:0007167,GO:0007178,GO:0007179,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007389,GO:0007552,GO:0007610,GO:0008069,GO:0008104,GO:0008134,GO:0008150,GO:0008152,GO:0008219,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009266,GO:0009303,GO:0009314,GO:0009408,GO:0009410,GO:0009411,GO:0009416,GO:0009628,GO:0009653,GO:0009719,GO:0009725,GO:0009798,GO:0009888,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009950,GO:0009953,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0010043,GO:0010212,GO:0010243,GO:0010332,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010563,GO:0010604,GO:0010605,GO:0010611,GO:0010613,GO:0010628,GO:0010629,GO:0010639,GO:0010646,GO:0010647,GO:0010941,GO:0010942,GO:0010990,GO:0012501,GO:0012505,GO:0014070,GO:0014742,GO:0014743,GO:0015030,GO:0016043,GO:0016070,GO:0016072,GO:0016333,GO:0016334,GO:0016485,GO:0016540,GO:0016604,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016886,GO:0017144,GO:0018130,GO:0018193,GO:0018209,GO:0018312,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019899,GO:0019900,GO:0019901,GO:0019953,GO:0022412,GO:0022414,GO:0022607,GO:0022616,GO:0023019,GO:0023051,GO:0023052,GO:0023056,GO:0030097,GO:0030099,GO:0030154,GO:0030225,GO:0030331,GO:0030534,GO:0030575,GO:0030576,GO:0030707,GO:0030808,GO:0030809,GO:0030855,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031334,GO:0031347,GO:0031349,GO:0031960,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032042,GO:0032101,GO:0032103,GO:0032200,GO:0032204,GO:0032205,GO:0032501,GO:0032502,GO:0032504,GO:0032507,GO:0032660,GO:0032700,GO:0032774,GO:0032868,GO:0032869,GO:0032870,GO:0032879,GO:0032880,GO:0032991,GO:0032993,GO:0033036,GO:0033043,GO:0033044,GO:0033143,GO:0033145,GO:0033146,GO:0033148,GO:0033365,GO:0033554,GO:0033683,GO:0033993,GO:0034248,GO:0034250,GO:0034504,GO:0034599,GO:0034605,GO:0034613,GO:0034614,GO:0034622,GO:0034641,GO:0034644,GO:0034645,GO:0034654,GO:0034660,GO:0035079,GO:0035080,GO:0035257,GO:0035258,GO:0035363,GO:0036094,GO:0036211,GO:0040008,GO:0040009,GO:0042220,GO:0042221,GO:0042391,GO:0042393,GO:0042493,GO:0042592,GO:0042769,GO:0042802,GO:0042826,GO:0042981,GO:0043067,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043254,GO:0043279,GO:0043388,GO:0043412,GO:0043434,GO:0043484,GO:0043502,GO:0043504,GO:0043523,GO:0043565,GO:0043900,GO:0043902,GO:0043933,GO:0044030,GO:0044057,GO:0044085,GO:0044087,GO:0044089,GO:0044093,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044454,GO:0044464,GO:0044703,GO:0045087,GO:0045185,GO:0045595,GO:0045597,GO:0045739,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045936,GO:0045944,GO:0045980,GO:0046034,GO:0046332,GO:0046483,GO:0047485,GO:0048037,GO:0048148,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048545,GO:0048583,GO:0048584,GO:0048609,GO:0048729,GO:0048731,GO:0048856,GO:0048869,GO:0048878,GO:0050662,GO:0050707,GO:0050708,GO:0050709,GO:0050710,GO:0050776,GO:0050778,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050801,GO:0050879,GO:0050881,GO:0050882,GO:0050896,GO:0051046,GO:0051048,GO:0051049,GO:0051051,GO:0051052,GO:0051053,GO:0051054,GO:0051094,GO:0051098,GO:0051099,GO:0051101,GO:0051103,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051223,GO:0051224,GO:0051235,GO:0051239,GO:0051240,GO:0051241,GO:0051252,GO:0051253,GO:0051254,GO:0051276,GO:0051287,GO:0051385,GO:0051427,GO:0051457,GO:0051604,GO:0051606,GO:0051641,GO:0051651,GO:0051704,GO:0051716,GO:0051881,GO:0051900,GO:0051901,GO:0055086,GO:0060249,GO:0060255,GO:0060341,GO:0060359,GO:0060390,GO:0060391,GO:0060429,GO:0062012,GO:0062014,GO:0065003,GO:0065004,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070201,GO:0070212,GO:0070412,GO:0070727,GO:0070848,GO:0070887,GO:0070911,GO:0071214,GO:0071241,GO:0071248,GO:0071294,GO:0071310,GO:0071363,GO:0071375,GO:0071417,GO:0071450,GO:0071451,GO:0071478,GO:0071482,GO:0071495,GO:0071559,GO:0071560,GO:0071704,GO:0071824,GO:0071840,GO:0072347,GO:0072521,GO:0072595,GO:0080090,GO:0080134,GO:0080135,GO:0090087,GO:0090092,GO:0090100,GO:0090257,GO:0090304,GO:0090305,GO:0097159,GO:0097305,GO:0097659,GO:0098687,GO:0098781,GO:0104004,GO:0140096,GO:0140097,GO:0140110,GO:1900180,GO:1900182,GO:1900371,GO:1900372,GO:1900407,GO:1900424,GO:1900426,GO:1900542,GO:1900543,GO:1901135,GO:1901214,GO:1901216,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901576,GO:1901652,GO:1901653,GO:1901654,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902175,GO:1902531,GO:1902679,GO:1902680,GO:1902882,GO:1903201,GO:1903203,GO:1903376,GO:1903506,GO:1903507,GO:1903508,GO:1903516,GO:1903518,GO:1903530,GO:1903531,GO:1903578,GO:1903579,GO:1903827,GO:1903829,GO:1904044,GO:1904181,GO:1904356,GO:1904357,GO:1904645,GO:1904646,GO:1904760,GO:1904762,GO:1904950,GO:1905076,GO:1905077,GO:1990404,GO:1990837,GO:1990966,GO:2000112,GO:2000113,GO:2000677,GO:2000679,GO:2001020,GO:2001022,GO:2001141,GO:2001169,GO:2001170,GO:2001233,GO:2001242,GO:2001251 2.4.2.30 0.0000000001018 69.0
HFD2_k127_1638364_26 Domain of unknown function (DUF4266) - - - 0.00000009213 59.0
HFD2_k127_1638364_3 Aspartate-ammonia ligase K01914 - 6.3.1.1 7.107e-197 619.0
HFD2_k127_1638364_4 PFAM Peptidase S10, serine carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 601.0
HFD2_k127_1638364_5 6-phosphofructokinase activity K00850,K00895,K21071 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008443,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0046872,GO:0047334,GO:0071704,GO:1901135 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008165 617.0
HFD2_k127_1638364_6 Aminotransferase class-III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006893 546.0
HFD2_k127_1638364_7 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 536.0
HFD2_k127_1638364_8 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 415.0
HFD2_k127_1638364_9 Sigma-54 interaction domain K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 352.0
HFD2_k127_1747069_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 378.0
HFD2_k127_1747069_1 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001601 273.0
HFD2_k127_1747069_2 PFAM Peptidase family M23 K08259 - 3.4.24.75 0.0000000000000000000000000002139 128.0
HFD2_k127_1747069_3 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.0000008115 52.0
HFD2_k127_1776878_0 transport K02027 - - 0.000000000000000000000000000000000000000000001846 178.0
HFD2_k127_1776878_1 PHP domain protein - - - 0.00000000000000000000000000000000000000006105 163.0
HFD2_k127_1821985_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 1.713e-250 784.0
HFD2_k127_1821985_1 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) - - - 2.659e-238 749.0
HFD2_k127_1821985_10 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 310.0
HFD2_k127_1821985_11 TIGRFAM polysaccharide deactylase family protein, PEP-CTERM locus subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004325 304.0
HFD2_k127_1821985_12 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000225 223.0
HFD2_k127_1821985_13 Dynamin family - - - 0.0000000000000000000000000000000000000000000137 182.0
HFD2_k127_1821985_14 Uncharacterized ACR, COG1993 K09137 - - 0.000000000000000000000000000000000007227 146.0
HFD2_k127_1821985_15 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000000000000000000002133 124.0
HFD2_k127_1821985_16 4Fe-4S binding domain - - - 0.0000000000000000000000005995 109.0
HFD2_k127_1821985_17 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.0000000000000000000002935 106.0
HFD2_k127_1821985_18 Biotin-requiring enzyme - - - 0.00000000006287 73.0
HFD2_k127_1821985_19 ubiE/COQ5 methyltransferase family K03183,K05929 - 2.1.1.103,2.1.1.163,2.1.1.201 0.0000000003376 70.0
HFD2_k127_1821985_2 PFAM Thiamine pyrophosphate K00175,K00187 - 1.2.7.11,1.2.7.3,1.2.7.7 5.032e-212 668.0
HFD2_k127_1821985_20 sodium ion export across plasma membrane K01573 GO:0003674,GO:0003824,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008948,GO:0015672,GO:0016829,GO:0016830,GO:0016831,GO:0030001,GO:0051179,GO:0051234 4.1.1.3 0.00000003796 66.0
HFD2_k127_1821985_21 PFAM PspC domain protein - - - 0.0000003478 55.0
HFD2_k127_1821985_3 Pyruvate:ferredoxin oxidoreductase core domain II K00186 - 1.2.7.7 9.186e-200 631.0
HFD2_k127_1821985_4 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 567.0
HFD2_k127_1821985_5 Acetyl-CoA hydrolase/transferase N-terminal domain K01067 - 3.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 531.0
HFD2_k127_1821985_6 oxaloacetate decarboxylase activity K01572 - 4.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 509.0
HFD2_k127_1821985_7 PFAM Aminotransferase class I and II K05825 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000575 529.0
HFD2_k127_1821985_8 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 451.0
HFD2_k127_1821985_9 PFAM Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008827 402.0
HFD2_k127_1849669_0 FAD linked oxidases, C-terminal domain K18930 - - 4.075e-251 815.0
HFD2_k127_1849669_1 Radical SAM superfamily K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000355 494.0
HFD2_k127_1849669_10 DoxX-like family K15977 - - 0.0000000000000000001088 102.0
HFD2_k127_1849669_11 multi-organism process - - - 0.000000000003067 79.0
HFD2_k127_1849669_12 Helix-turn-helix - - - 0.0000000001879 67.0
HFD2_k127_1849669_13 SNARE associated Golgi protein - - - 0.000000002403 72.0
HFD2_k127_1849669_2 OST-HTH/LOTUS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003646 353.0
HFD2_k127_1849669_3 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001549 258.0
HFD2_k127_1849669_4 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K14161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004909 258.0
HFD2_k127_1849669_5 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000002565 192.0
HFD2_k127_1849669_6 ADP-ribosylation factor family K06883 - - 0.0000000000000000000000000000000000000000000001384 190.0
HFD2_k127_1849669_7 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000001044 164.0
HFD2_k127_1849669_8 - - - - 0.00000000000000000000000000000001665 139.0
HFD2_k127_1849669_9 recA bacterial DNA recombination protein - - - 0.0000000000000000000009746 104.0
HFD2_k127_1876396_0 membrane K07027,K14205 - 2.3.2.3 4.421e-258 821.0
HFD2_k127_1876396_1 tRNA synthetases class I (W and Y) K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 432.0
HFD2_k127_1876396_11 chlorophyll binding - - - 0.0000000002435 70.0
HFD2_k127_1876396_12 thiolester hydrolase activity K06889,K07397 - - 0.00005044 55.0
HFD2_k127_1876396_2 Bacterial virulence protein (VirJ) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 440.0
HFD2_k127_1876396_3 major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000004088 247.0
HFD2_k127_1876396_4 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000009667 255.0
HFD2_k127_1876396_5 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000004436 196.0
HFD2_k127_1876396_6 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000004386 180.0
HFD2_k127_1876396_7 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.000000000000000000000000000000000000000008932 166.0
HFD2_k127_1876396_8 PFAM peptidase - - - 0.00000000000000000000000000000000000000002689 161.0
HFD2_k127_1876396_9 AAA domain K02282 - - 0.00000000000000000000003572 104.0
HFD2_k127_19097_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.345e-227 724.0
HFD2_k127_19097_1 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 3.822e-217 690.0
HFD2_k127_19097_10 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000002946 82.0
HFD2_k127_19097_11 oligosaccharyl transferase activity - - - 0.000000002141 72.0
HFD2_k127_19097_2 Belongs to the DegT DnrJ EryC1 family K02805 - 2.6.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 367.0
HFD2_k127_19097_3 Belongs to the SIS family. GutQ KpsF subfamily K01627,K03281,K06041 - 2.5.1.55,5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 361.0
HFD2_k127_19097_4 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 345.0
HFD2_k127_19097_5 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 291.0
HFD2_k127_19097_6 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000005043 243.0
HFD2_k127_19097_7 Bacterial membrane protein YfhO - - - 0.00000000000000000000000000000000007326 154.0
HFD2_k127_19097_8 PFAM Glycosyl transferase family 2 K07027 - - 0.0000000000000000000000000000006828 136.0
HFD2_k127_19097_9 Bacterial membrane protein YfhO - - - 0.0000000000000000001117 105.0
HFD2_k127_2007455_0 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 318.0
HFD2_k127_2007455_1 amino acid K03294,K13868 - - 0.000000000000000000000000000000000000000000000000000000000000000002535 233.0
HFD2_k127_2007455_2 Virulence factor BrkB K07058 - - 0.0000000000000000000004407 111.0
HFD2_k127_2007455_3 PFAM TrkA-N domain K10716 - - 0.000000000009172 68.0
HFD2_k127_2024382_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 2.414e-214 680.0
HFD2_k127_2024382_1 Prolyl oligopeptidase family - - - 1.26e-198 641.0
HFD2_k127_2024382_10 PFAM sodium K14445 - - 0.00000000000000000000001504 118.0
HFD2_k127_2024382_11 - - - - 0.0000000000000000001845 90.0
HFD2_k127_2024382_12 Pfam Hemerythrin HHE - - - 0.0000002606 61.0
HFD2_k127_2024382_13 Hydrolase Family 16 - - - 0.000001895 61.0
HFD2_k127_2024382_14 4Fe-4S single cluster domain of Ferredoxin I - - - 0.00003317 57.0
HFD2_k127_2024382_2 glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 558.0
HFD2_k127_2024382_3 electron transfer activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 540.0
HFD2_k127_2024382_4 Ring hydroxylating alpha subunit (catalytic domain) K00479 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 454.0
HFD2_k127_2024382_5 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006277 316.0
HFD2_k127_2024382_6 Alpha-tubulin suppressor and related RCC1 domain-containing proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003821 288.0
HFD2_k127_2024382_7 LysM domain - - - 0.000000000000000000000000000000000000000000000000000004432 198.0
HFD2_k127_2024382_8 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000005777 212.0
HFD2_k127_2024382_9 Transcriptional regulator K07979 - - 0.00000000000000000000000000000000000000002394 175.0
HFD2_k127_2039257_0 nitrite transmembrane transporter activity - - - 0.0 1026.0
HFD2_k127_2039257_1 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 373.0
HFD2_k127_2039257_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 344.0
HFD2_k127_2043549_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 2.781e-252 789.0
HFD2_k127_2043549_1 Probably functions as a manganese efflux pump - - - 0.0000000005978 71.0
HFD2_k127_205774_0 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006517 457.0
HFD2_k127_205774_1 KR domain K13774 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005 310.0
HFD2_k127_205774_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001448 237.0
HFD2_k127_205774_3 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000003701 204.0
HFD2_k127_205774_4 PFAM Cold-shock protein, DNA-binding K03704 - - 0.000000000000000000000000003218 114.0
HFD2_k127_205774_5 Alpha/beta hydrolase of unknown function (DUF1057) - - - 0.00000000000002664 86.0
HFD2_k127_205774_6 - - - - 0.00001721 57.0
HFD2_k127_2061083_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 398.0
HFD2_k127_2061083_1 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000000000000000004742 201.0
HFD2_k127_2061083_10 PSII is a light-driven water plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation K02710,K02712 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 - 0.00004851 46.0
HFD2_k127_2061083_11 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000368 49.0
HFD2_k127_2061083_2 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000001261 171.0
HFD2_k127_2061083_3 binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000000000003474 162.0
HFD2_k127_2061083_4 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000000001225 166.0
HFD2_k127_2061083_5 Protein kinase domain - - - 0.0000000000000000000000000002204 121.0
HFD2_k127_2061083_6 Could be involved in septation K06412 - - 0.0000000000000000000000001256 114.0
HFD2_k127_2061083_7 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000008476 105.0
HFD2_k127_2061083_8 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000001007 106.0
HFD2_k127_2061083_9 Predicted membrane protein (DUF2232) - - - 0.0000000002953 71.0
HFD2_k127_2071605_0 elongation factor G K02355 - - 9.723e-227 740.0
HFD2_k127_2071605_1 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000001663 203.0
HFD2_k127_2071605_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000001054 159.0
HFD2_k127_2071605_3 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000005734 134.0
HFD2_k127_2071605_4 TIGRFAM TonB family K03832 - - 0.000001343 61.0
HFD2_k127_2081913_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 1.383e-262 821.0
HFD2_k127_2081913_1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K07516 - 1.1.1.35 2.37e-234 749.0
HFD2_k127_2081913_2 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 3.379e-196 646.0
HFD2_k127_2081913_3 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 541.0
HFD2_k127_2081913_4 Belongs to the thiolase family K00632 - 2.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009076 517.0
HFD2_k127_2081913_5 RNA-metabolising metallo-beta-lactamase K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002749 433.0
HFD2_k127_2081913_6 Haloacid dehalogenase-like hydrolase K02566 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001132 298.0
HFD2_k127_2081913_7 PASTA K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.000000000000000000000000000000000000000000000000000000002574 220.0
HFD2_k127_2081913_8 Bacterial regulatory proteins, tetR family K13770 - - 0.0000000000000000000000000000000000000000000000001896 184.0
HFD2_k127_2081913_9 - - - - 0.000000000000000000000000000000000000000003279 173.0
HFD2_k127_2095582_0 FAD binding domain - - - 0.0 1086.0
HFD2_k127_2095582_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 475.0
HFD2_k127_2095582_2 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005602 399.0
HFD2_k127_2095582_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 338.0
HFD2_k127_2095582_4 Serine aminopeptidase, S33 K10222 - 3.7.1.8 0.000000000000000000000000000000000000000000000001418 183.0
HFD2_k127_2095582_5 Protein of unknown function (DUF805) - - - 0.000000000000000000000000000657 132.0
HFD2_k127_2130375_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 3.582e-228 719.0
HFD2_k127_2130375_1 asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007379 566.0
HFD2_k127_2130375_10 Leucine carboxyl methyltransferase - - - 0.00000000000000000000000000825 124.0
HFD2_k127_2130375_11 nuclear chromosome segregation - - - 0.0000000000000000000000005947 115.0
HFD2_k127_2130375_12 - - - - 0.00000000000000000000001185 112.0
HFD2_k127_2130375_13 nuclear chromosome segregation - - - 0.00000000000000000003247 102.0
HFD2_k127_2130375_14 domain protein - - - 0.0000000000000000001678 99.0
HFD2_k127_2130375_15 Forkhead associated domain - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006110,GO:0006140,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010563,GO:0010675,GO:0010677,GO:0016020,GO:0016310,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0030312,GO:0030808,GO:0030809,GO:0030811,GO:0030812,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0031330,GO:0036211,GO:0042325,GO:0042326,GO:0042802,GO:0043170,GO:0043412,GO:0043457,GO:0043467,GO:0043470,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045820,GO:0045912,GO:0045934,GO:0045936,GO:0045980,GO:0046777,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051174,GO:0051193,GO:0051195,GO:0051196,GO:0051198,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1900371,GO:1900372,GO:1900542,GO:1900543,GO:1901564,GO:1903578,GO:1903579,GO:2001169,GO:2001170 - 0.000000000001269 78.0
HFD2_k127_2130375_16 Phage-related minor tail protein - - - 0.00000000002605 74.0
HFD2_k127_2130375_17 nuclear chromosome segregation - - - 0.000009517 57.0
HFD2_k127_2130375_18 rRNA (cytosine-C5-)-methyltransferase activity K14835 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.310 0.0008302 46.0
HFD2_k127_2130375_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378,K13380 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004238 551.0
HFD2_k127_2130375_3 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 387.0
HFD2_k127_2130375_4 CDP-alcohol phosphatidyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000004737 243.0
HFD2_k127_2130375_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000001885 228.0
HFD2_k127_2130375_6 - - - - 0.00000000000000000000000000000000000000000000003809 192.0
HFD2_k127_2130375_7 PFAM EAL domain - - - 0.0000000000000000000000000000000000000000000002319 182.0
HFD2_k127_2130375_8 Cupin-like domain K19219 - - 0.00000000000000000000000000000000000000000006558 178.0
HFD2_k127_2130375_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000003526 142.0
HFD2_k127_2188895_0 Glycosyl hydrolase 36 superfamily, catalytic domain K00702,K13688 - 2.4.1.20 0.0 3726.0
HFD2_k127_2188895_1 glutaminyl-tRNA synthetase K01886 - 6.1.1.18 4.221e-259 831.0
HFD2_k127_2188895_10 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000009427 261.0
HFD2_k127_2188895_11 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000003626 232.0
HFD2_k127_2188895_12 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000002331 226.0
HFD2_k127_2188895_13 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000000000000011 202.0
HFD2_k127_2188895_14 oxidoreductase activity - - - 0.000000000000000000000000000000000000000000000000551 199.0
HFD2_k127_2188895_15 - - - - 0.000000000000000000000000000000000000000003916 158.0
HFD2_k127_2188895_16 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000001934 159.0
HFD2_k127_2188895_17 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000004438 142.0
HFD2_k127_2188895_18 Protein conserved in bacteria - - - 0.000000000000000000000000000000001347 137.0
HFD2_k127_2188895_19 cellulase activity - - - 0.00000004398 64.0
HFD2_k127_2188895_2 ATP dependent DNA ligase domain protein K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008784 600.0
HFD2_k127_2188895_3 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885,K09698 - 6.1.1.17,6.1.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007392 548.0
HFD2_k127_2188895_4 ATP dependent DNA ligase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004549 512.0
HFD2_k127_2188895_5 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005642 428.0
HFD2_k127_2188895_6 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 400.0
HFD2_k127_2188895_7 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 388.0
HFD2_k127_2188895_8 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit K01768,K07315 - 3.1.3.3,4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 297.0
HFD2_k127_2188895_9 NADPH-dependent FMN reductase K19784 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002857 257.0
HFD2_k127_221055_0 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 613.0
HFD2_k127_221055_1 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 554.0
HFD2_k127_221055_10 NUDIX domain K00077,K01092,K03574,K03795 - 1.1.1.169,3.1.3.25,3.6.1.55,4.99.1.3 0.0000000000000000000000000000000000000000000000000001656 190.0
HFD2_k127_221055_11 Radical SAM domain protein - - - 0.000000000000000000000000000000000000000007403 175.0
HFD2_k127_221055_12 PFAM thioesterase superfamily protein K07107 - - 0.000000000000000000000000002546 121.0
HFD2_k127_221055_13 Uncharacterized conserved protein (DUF2203) - - - 0.00000000000000000000005592 102.0
HFD2_k127_221055_14 ATP-binding protein K04562 - - 0.00000000000000004982 97.0
HFD2_k127_221055_15 COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 K00528 - 1.18.1.2,1.19.1.1 0.000000004507 68.0
HFD2_k127_221055_16 histone H2A K63-linked ubiquitination K01120,K01768,K11894,K11913,K12132 - 2.7.11.1,3.1.4.17,4.6.1.1 0.00003055 58.0
HFD2_k127_221055_17 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000485 55.0
HFD2_k127_221055_2 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 515.0
HFD2_k127_221055_3 cytochrome p450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 505.0
HFD2_k127_221055_4 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004123 456.0
HFD2_k127_221055_5 Multicopper oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006037 399.0
HFD2_k127_221055_6 tRNA thio-modification K03151 GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 355.0
HFD2_k127_221055_7 dihydrofolate reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000383 330.0
HFD2_k127_221055_8 peptidase dimerisation domain protein K01295 - 3.4.17.11 0.000000000000000000000000000000000000000000000000000000000000000000000002561 274.0
HFD2_k127_221055_9 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000009347 227.0
HFD2_k127_222064_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006176 552.0
HFD2_k127_222064_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002975 530.0
HFD2_k127_222064_10 - - - - 0.0000000000000000000000000000000000000000003191 182.0
HFD2_k127_222064_11 SnoaL-like domain K06893 - - 0.0000000000000000000000000000000000001048 145.0
HFD2_k127_222064_12 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000002346 145.0
HFD2_k127_222064_13 Pfam:Methyltransf_26 - - - 0.000000000000000000000000000000001325 151.0
HFD2_k127_222064_14 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752,K13818 - 2.7.7.77 0.0000000000000000000000000000000694 138.0
HFD2_k127_222064_15 Pyridoxamine 5'-phosphate oxidase like - - - 0.000000000000000000000000000001173 141.0
HFD2_k127_222064_16 acetyltransferase - - - 0.000000000000000000000000000007584 124.0
HFD2_k127_222064_17 protein-disulfide reductase activity - - - 0.0000000000000000001111 102.0
HFD2_k127_222064_18 Domain of unknown function (DUF4442) - - - 0.0000000000000000002097 100.0
HFD2_k127_222064_2 Belongs to the CarB family K01955 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 498.0
HFD2_k127_222064_3 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000513 325.0
HFD2_k127_222064_4 Carbamoyltransferase K00612 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001744 264.0
HFD2_k127_222064_5 PFAM Peptidase C26 K07010 - - 0.00000000000000000000000000000000000000000000000000000000000003947 244.0
HFD2_k127_222064_6 Phospholipid methyltransferase - - - 0.000000000000000000000000000000000000000000000001986 178.0
HFD2_k127_222064_7 Peptidase family M23 K21472 - - 0.0000000000000000000000000000000000000000000003397 175.0
HFD2_k127_222064_8 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000008002 174.0
HFD2_k127_222064_9 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000007081 171.0
HFD2_k127_222508_0 Proposed role in polysaccahride synthesis K07077 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 527.0
HFD2_k127_222508_1 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005754 372.0
HFD2_k127_222508_2 N-acetylglucosaminylinositol deacetylase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000296 274.0
HFD2_k127_222508_3 - - - - 0.000000000000000000000000000000000000000000005707 171.0
HFD2_k127_222508_4 - - - - 0.0004358 48.0
HFD2_k127_2387000_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 9.582e-305 970.0
HFD2_k127_2387000_1 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 1.305e-248 820.0
HFD2_k127_2387000_10 Trypsin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 370.0
HFD2_k127_2387000_11 gluconolactonase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001743 310.0
HFD2_k127_2387000_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000133 265.0
HFD2_k127_2387000_13 DNA alkylation repair enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000718 264.0
HFD2_k127_2387000_14 PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP K20276 - - 0.0000000000000000000000000000000000000000000000000000000000000000004838 263.0
HFD2_k127_2387000_15 protein related to plant photosystem II stability assembly factor - - - 0.0000000000000000000000000000000000000000000000000000000000000352 237.0
HFD2_k127_2387000_16 DNA-templated transcription, initiation - - - 0.00000000000000000000000000000000000000000000000000000000003832 213.0
HFD2_k127_2387000_17 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000001629 206.0
HFD2_k127_2387000_18 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 0.000000000000000000000000000000000000000000000000000102 198.0
HFD2_k127_2387000_19 Domain of unknown function (DUF4405) - - - 0.00000000000000000000000000000000000000000000000004074 203.0
HFD2_k127_2387000_2 Protein tyrosine kinase K12132 - 2.7.11.1 2.07e-197 649.0
HFD2_k127_2387000_20 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000002604 180.0
HFD2_k127_2387000_21 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000001725 190.0
HFD2_k127_2387000_22 SMART phosphoesterase PHP domain protein - - - 0.0000000000000000000000000000000000000003975 169.0
HFD2_k127_2387000_23 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000009076 143.0
HFD2_k127_2387000_24 PFAM peptidase M52 hydrogen uptake protein K03605 - - 0.0000000000000000000000000000000003384 139.0
HFD2_k127_2387000_25 - - - - 0.000000000000000000000000000000002358 140.0
HFD2_k127_2387000_26 Metallo-peptidase family M12 - - - 0.000000000000000000000000000001137 143.0
HFD2_k127_2387000_27 - - - - 0.000000000000000000000004983 107.0
HFD2_k127_2387000_28 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000005269 93.0
HFD2_k127_2387000_29 domain protein - - - 0.000000000000004485 86.0
HFD2_k127_2387000_3 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 606.0
HFD2_k127_2387000_30 PHP-associated - - - 0.000000000000007489 89.0
HFD2_k127_2387000_31 permease K07243 - - 0.0000000000001698 76.0
HFD2_k127_2387000_32 Protein of unknown function (DUF1624) - - - 0.0000000000001833 76.0
HFD2_k127_2387000_33 - - - - 0.0000000000002144 81.0
HFD2_k127_2387000_35 Methyltransferase - - - 0.000000005426 65.0
HFD2_k127_2387000_36 nuclear chromosome segregation - - - 0.0000008165 60.0
HFD2_k127_2387000_4 succinyl-diaminopimelate desuccinylase activity K01295 - 3.4.17.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 544.0
HFD2_k127_2387000_5 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007051 492.0
HFD2_k127_2387000_6 Permease YjgP YjgQ family protein K07091,K11720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 487.0
HFD2_k127_2387000_7 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282,K18008 - 1.12.2.1,1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 459.0
HFD2_k127_2387000_8 Belongs to the glycosyl hydrolase 57 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007096 469.0
HFD2_k127_2387000_9 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 473.0
HFD2_k127_2429008_0 5TM C-terminal transporter carbon starvation CstA K06200 - - 1.852e-239 751.0
HFD2_k127_2429008_1 peptidoglycan-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006286 366.0
HFD2_k127_2429008_10 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000008316 107.0
HFD2_k127_2429008_11 His Kinase A (phosphoacceptor) domain K11527 - 2.7.13.3 0.0000000000000000001877 102.0
HFD2_k127_2429008_12 Protein of unknown function (DUF4242) - - - 0.000000000001416 79.0
HFD2_k127_2429008_13 Glutaredoxin K03676 - - 0.00000001381 57.0
HFD2_k127_2429008_14 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07714 - - 0.0008038 46.0
HFD2_k127_2429008_2 amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005078 309.0
HFD2_k127_2429008_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005993 287.0
HFD2_k127_2429008_4 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000004336 237.0
HFD2_k127_2429008_5 heme binding K21472 - - 0.00000000000000000000000000000000000000000000000000000001373 207.0
HFD2_k127_2429008_6 Phosphodiester glycosidase - - - 0.0000000000000000000000000000000000000000000000000000009066 205.0
HFD2_k127_2429008_7 Domain of unknown function (DUF4388) K12132 - 2.7.11.1 0.000000000000000000000000000001885 136.0
HFD2_k127_2429008_8 Protein of unknown function (DUF1326) - - - 0.0000000000000000000000000001229 125.0
HFD2_k127_2429008_9 Adenylate Guanylate cyclase - - - 0.0000000000000000000000001263 117.0
HFD2_k127_2449406_0 ASPIC and UnbV - - - 3.908e-275 875.0
HFD2_k127_2449406_1 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 2.654e-234 745.0
HFD2_k127_2449406_10 PFAM periplasmic binding protein LacI transcriptional regulator K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000001482 256.0
HFD2_k127_2449406_11 GDSL-like Lipase/Acylhydrolase - - - 0.00000000000000000000000000000000000000000000000000000000001841 231.0
HFD2_k127_2449406_12 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000002396 168.0
HFD2_k127_2449406_2 metallopeptidase activity K01179 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0010383,GO:0010410,GO:0010411,GO:0016052,GO:0016787,GO:0016798,GO:0033946,GO:0043170,GO:0044036,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044419,GO:0051704,GO:0052736,GO:0071554,GO:0071704,GO:0085030,GO:1901575,GO:2000895,GO:2000899 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006138 605.0
HFD2_k127_2449406_3 Glycoside hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009379 525.0
HFD2_k127_2449406_4 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 492.0
HFD2_k127_2449406_5 ABC transporter K10441,K10542 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005355 430.0
HFD2_k127_2449406_6 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003842 427.0
HFD2_k127_2449406_7 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 310.0
HFD2_k127_2449406_8 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 299.0
HFD2_k127_2449406_9 Belongs to the binding-protein-dependent transport system permease family K17214 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001208 268.0
HFD2_k127_2537920_0 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 423.0
HFD2_k127_2537920_1 Histidine kinase K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007804 427.0
HFD2_k127_2537920_10 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - 0.000000000000000001174 92.0
HFD2_k127_2537920_11 Dystroglycan-type cadherin-like domains. - - - 0.000000000000000009674 98.0
HFD2_k127_2537920_12 COG0457 FOG TPR repeat - - - 0.00000000007909 69.0
HFD2_k127_2537920_13 monooxygenase activity K00688,K15760,K16157,K16242,K18223,K22353,K22357 GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0008150,GO:0008152,GO:0009987,GO:0015049,GO:0015050,GO:0015947,GO:0016491,GO:0016705,GO:0016709,GO:0032991,GO:0043446,GO:0044237,GO:0055114,GO:0071704,GO:1902494 1.14.13.227,1.14.13.236,1.14.13.25,1.14.13.69,2.4.1.1 0.0005324 49.0
HFD2_k127_2537920_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006397 375.0
HFD2_k127_2537920_3 microcin C7 resistance K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000434 281.0
HFD2_k127_2537920_4 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000000006452 188.0
HFD2_k127_2537920_5 ethanolamine catabolic process K04027 - - 0.0000000000000000000000000000000000000727 143.0
HFD2_k127_2537920_6 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000255 144.0
HFD2_k127_2537920_7 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028,K08697 - - 0.000000000000000000000000002514 117.0
HFD2_k127_2537920_8 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000000000000000005819 115.0
HFD2_k127_2537920_9 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.0000000000000000000015 98.0
HFD2_k127_2571359_0 aminopeptidase activity K01301 - 3.4.17.21 3.71e-273 865.0
HFD2_k127_2571359_1 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001237 287.0
HFD2_k127_2571359_2 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003873 265.0
HFD2_k127_2571359_3 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000009773 206.0
HFD2_k127_2571359_4 Low affinity iron permease - - - 0.00000000000000000000000000000000000000000428 166.0
HFD2_k127_2571359_5 - - - - 0.000000000000000000000000000000000002726 157.0
HFD2_k127_2571359_6 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000001051 121.0
HFD2_k127_2571450_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 6.807e-213 691.0
HFD2_k127_2571450_1 NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 566.0
HFD2_k127_2571450_10 ZIP Zinc transporter K07238,K11021,K16267 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002698 280.0
HFD2_k127_2571450_11 cAMP biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004384 284.0
HFD2_k127_2571450_12 MacB-like periplasmic core domain K02003,K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001346 274.0
HFD2_k127_2571450_13 Mitochondrial biogenesis AIM24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001063 270.0
HFD2_k127_2571450_14 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000001551 243.0
HFD2_k127_2571450_15 COG1136 ABC-type antimicrobial peptide transport system ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000003714 250.0
HFD2_k127_2571450_16 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000007951 225.0
HFD2_k127_2571450_17 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000732 224.0
HFD2_k127_2571450_18 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000005713 203.0
HFD2_k127_2571450_19 Cadherin repeats. - - - 0.00000000000000000000000000000000000000000000005461 194.0
HFD2_k127_2571450_2 Domain of unknown function (DUF4331) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 549.0
HFD2_k127_2571450_20 Protein of unknown function (DUF1569) - - - 0.000000000000000000000000000000000000000000001733 169.0
HFD2_k127_2571450_21 Probable molybdopterin binding domain - - - 0.00000000000000000000000000000000000000002632 162.0
HFD2_k127_2571450_22 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000002228 165.0
HFD2_k127_2571450_23 PIN domain - - - 0.000000000000000000000000000000000001064 147.0
HFD2_k127_2571450_24 permease - - - 0.00000000000000000000000000000001812 141.0
HFD2_k127_2571450_25 Metallo-peptidase family M12 - - - 0.0000000000000000000000000000003136 143.0
HFD2_k127_2571450_26 Belongs to the arginase family K01476 - 3.5.3.1 0.000000000000000000000000000001352 141.0
HFD2_k127_2571450_27 ATP synthesis coupled proton transport K02109 - - 0.00000000000000000000000000001591 127.0
HFD2_k127_2571450_28 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.00000000000000000000000000001981 124.0
HFD2_k127_2571450_29 ABC-type sugar transport system periplasmic component K10439 - - 0.00000000000000000000000000002475 130.0
HFD2_k127_2571450_3 proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005202 548.0
HFD2_k127_2571450_30 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000002108 118.0
HFD2_k127_2571450_32 Regulatory protein, FmdB - - - 0.000000000000000000003713 98.0
HFD2_k127_2571450_33 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000003323 108.0
HFD2_k127_2571450_34 - - - - 0.00000000000000000003345 103.0
HFD2_k127_2571450_35 PFAM outer membrane efflux protein - - - 0.000000000000000004969 98.0
HFD2_k127_2571450_36 - - GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007 - 0.0000000000000008811 79.0
HFD2_k127_2571450_37 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000009573 90.0
HFD2_k127_2571450_4 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004777 501.0
HFD2_k127_2571450_5 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 445.0
HFD2_k127_2571450_6 PFAM Nucleotidyl transferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004133 400.0
HFD2_k127_2571450_7 HI0933-like protein K07007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006775 395.0
HFD2_k127_2571450_8 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008559 325.0
HFD2_k127_2571450_9 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003426 303.0
HFD2_k127_258393_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.532e-281 876.0
HFD2_k127_258393_1 Chemotaxis sensory transducer K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 459.0
HFD2_k127_258393_10 PFAM CheW domain protein K03408 - - 0.0000000000000000000000000000000000284 156.0
HFD2_k127_258393_11 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000003599 143.0
HFD2_k127_258393_13 Formiminotransferase domain, N-terminal subdomain K00603,K13990 - 2.1.2.5,4.3.1.4 0.000000000000000003233 89.0
HFD2_k127_258393_14 regulator, PATAN and FRGAF domain-containing - - - 0.000008046 56.0
HFD2_k127_258393_2 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003609 362.0
HFD2_k127_258393_3 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005816 323.0
HFD2_k127_258393_4 Peptidase M15 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007456 306.0
HFD2_k127_258393_5 PBS lyase HEAT domain protein repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003923 299.0
HFD2_k127_258393_6 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000001718 234.0
HFD2_k127_258393_7 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000001486 222.0
HFD2_k127_258393_8 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000001476 202.0
HFD2_k127_258393_9 cheY-homologous receiver domain K03413 - - 0.0000000000000000000000000000000000000000001335 165.0
HFD2_k127_2598569_0 Pyrrolo-quinoline quinone K00114 - 1.1.2.8 3.843e-264 867.0
HFD2_k127_2598569_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K15408 - 1.9.3.1 8.911e-261 841.0
HFD2_k127_2598569_10 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000001763 116.0
HFD2_k127_2598569_11 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000002444 112.0
HFD2_k127_2598569_12 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.000000000000000000001705 104.0
HFD2_k127_2598569_13 Parallel beta-helix repeats - - - 0.000000000006103 79.0
HFD2_k127_2598569_2 amino acid transport K02030,K16254 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009182 333.0
HFD2_k127_2598569_3 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K17223 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 316.0
HFD2_k127_2598569_4 cytochrome c oxidase K02351 - - 0.00000000000000000000000000000000000000000000000000000000000002774 230.0
HFD2_k127_2598569_5 Metallo-peptidase family M12 - - - 0.00000000000000000000000000000000000000000009762 183.0
HFD2_k127_2598569_6 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.00000000000000000000000000000000000000002911 164.0
HFD2_k127_2598569_7 lysyltransferase activity K07027 - - 0.00000000000000000000000000000000002057 154.0
HFD2_k127_2598569_8 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000002057 154.0
HFD2_k127_2598569_9 Cytochrome c oxidase subunit III - - - 0.000000000000000000000000000002869 139.0
HFD2_k127_2624386_0 Insulinase (Peptidase family M16) K07263 - - 3.111e-257 805.0
HFD2_k127_2624386_1 - - - - 0.000000001555 66.0
HFD2_k127_2624386_2 - - - - 0.000000244 60.0
HFD2_k127_2627478_0 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane - - - 0.0 1323.0
HFD2_k127_2627478_1 cellulose binding - - - 0.0 1095.0
HFD2_k127_2627478_10 Zn peptidase - - - 0.0000000000000000000000000000000000004446 155.0
HFD2_k127_2627478_11 macromolecule localization K01992,K09690 - - 0.0000000000000000000000000000000000006642 162.0
HFD2_k127_2627478_12 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000009465 135.0
HFD2_k127_2627478_13 Pfam:DUF955 - - - 0.00000000000000000000000000000009979 139.0
HFD2_k127_2627478_14 Belongs to the peptidase S8 family - - - 0.000000000000000000000000049 125.0
HFD2_k127_2627478_15 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000001168 105.0
HFD2_k127_2627478_2 PFAM Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 419.0
HFD2_k127_2627478_3 Phospholipase D Transphosphatidylase K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004712 304.0
HFD2_k127_2627478_4 pfam abc K09691 - - 0.000000000000000000000000000000000000000000000000000000000000001221 238.0
HFD2_k127_2627478_5 calcium- and calmodulin-responsive adenylate cyclase activity K01406,K07004 - 3.4.24.40 0.000000000000000000000000000000000000000000000000000000000000454 235.0
HFD2_k127_2627478_6 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843 - - 0.0000000000000000000000000000000000000000000000000000000376 224.0
HFD2_k127_2627478_7 methyltransferase - - - 0.000000000000000000000000000000000000000000000000002444 207.0
HFD2_k127_2627478_8 KR domain - - - 0.000000000000000000000000000000000000000003797 169.0
HFD2_k127_2627478_9 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000002174 161.0
HFD2_k127_2648041_0 two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003621 543.0
HFD2_k127_2648041_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 527.0
HFD2_k127_2648041_10 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004902 285.0
HFD2_k127_2648041_11 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008483 291.0
HFD2_k127_2648041_12 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000781 276.0
HFD2_k127_2648041_13 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000000000001228 218.0
HFD2_k127_2648041_14 riboflavin synthase, alpha K00793 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 0.0000000000000000000000000000000000000000000000000000004217 199.0
HFD2_k127_2648041_15 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000005506 192.0
HFD2_k127_2648041_16 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000001611 198.0
HFD2_k127_2648041_17 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000000000000003296 162.0
HFD2_k127_2648041_18 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000001128 158.0
HFD2_k127_2648041_19 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000004699 143.0
HFD2_k127_2648041_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 496.0
HFD2_k127_2648041_20 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000001125 137.0
HFD2_k127_2648041_21 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000000003396 131.0
HFD2_k127_2648041_22 Fibronectin-binding A domain protein - - - 0.0000000000000000000000000002588 131.0
HFD2_k127_2648041_23 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000000004883 119.0
HFD2_k127_2648041_24 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000001871 115.0
HFD2_k127_2648041_25 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000003743 107.0
HFD2_k127_2648041_26 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000003846 118.0
HFD2_k127_2648041_27 TPR repeat - - - 0.0000000000000135 84.0
HFD2_k127_2648041_28 Protein of unknown function (DUF2662) - - - 0.0000000000003619 81.0
HFD2_k127_2648041_29 Belongs to the UPF0109 family K06960 - - 0.000000000001296 74.0
HFD2_k127_2648041_3 His Kinase A (phosphoacceptor) domain K13598 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008415 426.0
HFD2_k127_2648041_30 - - - - 0.000000000101 74.0
HFD2_k127_2648041_31 Bacterial regulatory protein, Fis family - - - 0.0000000001016 70.0
HFD2_k127_2648041_32 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.0000002152 63.0
HFD2_k127_2648041_33 RDD family - - - 0.000001053 61.0
HFD2_k127_2648041_34 zinc-ribbon domain - - - 0.0001171 52.0
HFD2_k127_2648041_4 PFAM SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 389.0
HFD2_k127_2648041_5 PFAM Formiminotransferase K00603 - 2.1.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 351.0
HFD2_k127_2648041_6 Belongs to the CinA family K03742 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 338.0
HFD2_k127_2648041_7 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 355.0
HFD2_k127_2648041_8 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 340.0
HFD2_k127_2648041_9 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000157 298.0
HFD2_k127_2653936_0 Alpha-amylase domain K05343 - 3.2.1.1,5.4.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 604.0
HFD2_k127_2653936_1 Peptidase family S41 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001744 269.0
HFD2_k127_2653936_2 Glycoside hydrolase, family 20, catalytic core K12373 - 3.2.1.52 0.00002792 49.0
HFD2_k127_2684279_0 double-stranded DNA 3'-5' exodeoxyribonuclease activity K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006388 280.0
HFD2_k127_2735524_0 PFAM peptidase S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002435 264.0
HFD2_k127_2735524_1 peptidyl-tyrosine sulfation - - - 0.000000000000854 81.0
HFD2_k127_2735524_2 PFAM YdjC family protein K03478 - 3.5.1.105 0.00008456 46.0
HFD2_k127_2739568_0 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 302.0
HFD2_k127_2739568_1 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000002176 141.0
HFD2_k127_2739568_2 rod shape-determining protein MreD K03571 - - 0.000005109 55.0
HFD2_k127_2741129_0 Sortilin, neurotensin receptor 3, - - - 0.0 1214.0
HFD2_k127_2741129_1 lysine biosynthetic process via aminoadipic acid - - - 5.336e-256 810.0
HFD2_k127_2741129_10 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003031 398.0
HFD2_k127_2741129_11 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000328 329.0
HFD2_k127_2741129_12 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001196 299.0
HFD2_k127_2741129_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000208 252.0
HFD2_k127_2741129_14 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000001117 186.0
HFD2_k127_2741129_15 Belongs to the ompA family - - - 0.00000000000000000000000000000000000009188 150.0
HFD2_k127_2741129_16 chlorophyll binding K03286 - - 0.0000000000000000000000000000000000001896 155.0
HFD2_k127_2741129_17 cheY-homologous receiver domain K03413 - - 0.000000000000000000000000000000000001633 142.0
HFD2_k127_2741129_18 electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration K05574 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.00000000000000000000000000000000002817 140.0
HFD2_k127_2741129_19 - - - - 0.000000000000000000000000000000006089 135.0
HFD2_k127_2741129_2 TonB dependent receptor - - - 3.015e-252 820.0
HFD2_k127_2741129_20 Belongs to the glycosyl hydrolase 18 family - - - 0.00000000000000000000000000000006052 142.0
HFD2_k127_2741129_21 Peptidyl-prolyl cis-trans K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000002133 135.0
HFD2_k127_2741129_22 FecR protein - - - 0.0000000000000000000000000001709 125.0
HFD2_k127_2741129_23 YCII-related domain - - - 0.000000000000000002873 89.0
HFD2_k127_2741129_24 redox protein, regulator of disulfide bond formation - - - 0.0000000000000005061 87.0
HFD2_k127_2741129_25 PspC domain - - - 0.000000000000005378 86.0
HFD2_k127_2741129_26 nuclear chromosome segregation - - - 0.000000000000005568 85.0
HFD2_k127_2741129_27 nuclear chromosome segregation - - - 0.000000000000006033 85.0
HFD2_k127_2741129_28 Immunity protein 35 - - - 0.0000008307 55.0
HFD2_k127_2741129_3 pyrroloquinoline quinone binding - - - 3.43e-200 634.0
HFD2_k127_2741129_4 Peptidase S9, prolyl oligopeptidase active site domain protein K01322 - 3.4.21.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 599.0
HFD2_k127_2741129_5 Putative glucoamylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007608 563.0
HFD2_k127_2741129_6 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000425 494.0
HFD2_k127_2741129_7 Chase2 domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009697 437.0
HFD2_k127_2741129_8 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007053 404.0
HFD2_k127_2741129_9 PFAM sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 393.0
HFD2_k127_2743724_0 Lon protease (S16) C-terminal proteolytic domain K01338 - 3.4.21.53 0.0 1087.0
HFD2_k127_2743724_1 Molybdopterin oxidoreductase Fe4S4 domain - - - 4.277e-267 867.0
HFD2_k127_2743724_10 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 473.0
HFD2_k127_2743724_11 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 466.0
HFD2_k127_2743724_12 AraC family transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008461 454.0
HFD2_k127_2743724_13 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006287 463.0
HFD2_k127_2743724_14 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 444.0
HFD2_k127_2743724_15 DNA ligase K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 391.0
HFD2_k127_2743724_16 Domain of Unknown Function (DUF1259) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008411 353.0
HFD2_k127_2743724_17 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008953 340.0
HFD2_k127_2743724_18 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007101 311.0
HFD2_k127_2743724_19 3-demethylubiquinone-9 3-methyltransferase K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008317 293.0
HFD2_k127_2743724_2 COG0513 Superfamily II DNA and RNA helicases K17675 - 3.6.4.13 2.206e-246 784.0
HFD2_k127_2743724_20 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain K17736 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000172 286.0
HFD2_k127_2743724_21 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003704 287.0
HFD2_k127_2743724_22 ATPases associated with a variety of cellular activities K05847 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005845 274.0
HFD2_k127_2743724_23 dna ligase K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000002752 262.0
HFD2_k127_2743724_24 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002883 250.0
HFD2_k127_2743724_25 Chitin-binding domain type 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000009624 256.0
HFD2_k127_2743724_26 Pfam Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000000000000000000003633 212.0
HFD2_k127_2743724_27 acetyltransferase K00661 - 2.3.1.79 0.0000000000000000000000000000000000000000000000000000003498 198.0
HFD2_k127_2743724_28 Glyoxalase-like domain K08234 - - 0.000000000000000000000000000000000000000000000000000009077 193.0
HFD2_k127_2743724_29 Lipocalin / cytosolic fatty-acid binding protein family K03098 - - 0.00000000000000000000000000000000000000000000000000001556 195.0
HFD2_k127_2743724_3 Prolyl oligopeptidase K01322 - 3.4.21.26 2.779e-222 710.0
HFD2_k127_2743724_30 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000000000000001629 192.0
HFD2_k127_2743724_31 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000008945 164.0
HFD2_k127_2743724_32 Thioredoxin K03671,K03672 - 1.8.1.8 0.0000000000000000000000000000000000000000001511 163.0
HFD2_k127_2743724_33 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000000000000000003419 180.0
HFD2_k127_2743724_34 endonuclease activity K07451 - - 0.00000000000000000000000000000000000000001551 172.0
HFD2_k127_2743724_35 YCII-related domain - - - 0.000000000000000000000000000000000000003703 161.0
HFD2_k127_2743724_36 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000000000005765 129.0
HFD2_k127_2743724_37 lactoylglutathione lyase activity - - - 0.00000000000000000000000000001132 129.0
HFD2_k127_2743724_38 short-chain dehydrogenase - - - 0.0000000000000000000000000004646 115.0
HFD2_k127_2743724_39 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000006686 118.0
HFD2_k127_2743724_4 belongs to the sigma-70 factor family K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 592.0
HFD2_k127_2743724_40 - - - - 0.000000000000000000000000004498 128.0
HFD2_k127_2743724_41 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0000000000000000000001453 97.0
HFD2_k127_2743724_42 Transglycosylase SLT domain - - - 0.00000000000003885 84.0
HFD2_k127_2743724_43 Transglutaminase - - - 0.0000000000004616 77.0
HFD2_k127_2743724_45 SEC-C motif - - - 0.000006504 51.0
HFD2_k127_2743724_46 Protein of unknown function (DUF3995) - - - 0.000009185 54.0
HFD2_k127_2743724_47 Putative prokaryotic signal transducing protein - - - 0.00003972 53.0
HFD2_k127_2743724_48 FtsX-like permease family - - - 0.0006429 45.0
HFD2_k127_2743724_5 Putative methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006374 532.0
HFD2_k127_2743724_6 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000439 524.0
HFD2_k127_2743724_7 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 529.0
HFD2_k127_2743724_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 481.0
HFD2_k127_2743724_9 COG0208 Ribonucleotide reductase, beta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004743 474.0
HFD2_k127_2745839_0 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 3.443e-249 797.0
HFD2_k127_2745839_1 Belongs to the sigma-70 factor family. ECF subfamily - - - 1.579e-200 631.0
HFD2_k127_2745839_10 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000001223 177.0
HFD2_k127_2745839_12 Subtilase family - - - 0.0000000000000000000000000000000000000000003119 183.0
HFD2_k127_2745839_13 DoxX-like family - - - 0.000000000000000000000000000000000005015 150.0
HFD2_k127_2745839_14 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000003443 136.0
HFD2_k127_2745839_15 MgtC family K07507 - - 0.0000000000000000000000000000000003655 142.0
HFD2_k127_2745839_16 - - - - 0.000000000000000000000000000000004924 137.0
HFD2_k127_2745839_17 Uncharacterized conserved protein (DUF2277) - - - 0.00000000000000000000000000002641 130.0
HFD2_k127_2745839_18 Homeodomain-like domain K07497 - - 0.000000000000000000000000007517 114.0
HFD2_k127_2745839_19 Tetratricopeptide repeat - - - 0.00000000000000000000000008158 123.0
HFD2_k127_2745839_2 Neutral/alkaline non-lysosomal ceramidase, C-terminal K12349 - 3.5.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 639.0
HFD2_k127_2745839_21 Domain of unknown function (DU1801) - - - 0.000000000000000000001903 99.0
HFD2_k127_2745839_22 Caspase domain - - - 0.00000000000000003231 98.0
HFD2_k127_2745839_24 PBS lyase HEAT-like repeat - - - 0.000000000001955 82.0
HFD2_k127_2745839_26 helix_turn_helix, Lux Regulon - - - 0.0006113 50.0
HFD2_k127_2745839_3 NmrA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 433.0
HFD2_k127_2745839_4 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006332 313.0
HFD2_k127_2745839_5 ABC transporter, ATP-binding protein K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006083 287.0
HFD2_k127_2745839_6 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003098 307.0
HFD2_k127_2745839_7 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000000000000000000000000000000000000000000008699 242.0
HFD2_k127_2745839_8 2OG-Fe(II) oxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000002249 229.0
HFD2_k127_2745839_9 YCII-related domain - - - 0.0000000000000000000000000000000000000000000000000000001312 197.0
HFD2_k127_2745998_0 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000025 302.0
HFD2_k127_2745998_1 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.000000000000000000000000000000000000000000000000000000000000000000000000008705 269.0
HFD2_k127_2745998_10 ACT domain K00003,K00928,K12524 - 1.1.1.3,2.7.2.4 0.0000000000001992 77.0
HFD2_k127_2745998_11 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000002754 68.0
HFD2_k127_2745998_2 PFAM ABC transporter related K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003209 271.0
HFD2_k127_2745998_3 PFAM LemA family protein K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000001475 242.0
HFD2_k127_2745998_4 Allophanate hydrolase subunit 2 K06350 - - 0.00000000000000000000000000000000000000000000000000000013 203.0
HFD2_k127_2745998_5 TPM domain K06872 - - 0.0000000000000000000000000000000000000000000000005713 190.0
HFD2_k127_2745998_7 binding-protein-dependent transport systems inner membrane component K02050 - - 0.000000000000000000000000000000000000001732 169.0
HFD2_k127_2745998_8 - - - - 0.00000000000000000000000000000048 134.0
HFD2_k127_2745998_9 - - - - 0.0000000000000000000000000007442 125.0
HFD2_k127_2747217_0 TIGRFAM Outer membrane protein K13735,K20276 - - 0.0 1418.0
HFD2_k127_2747217_1 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 632.0
HFD2_k127_2747217_10 Bacterial regulatory proteins, tetR family - - - 0.00000006002 63.0
HFD2_k127_2747217_12 RHS Repeat - - - 0.0002185 50.0
HFD2_k127_2747217_2 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 460.0
HFD2_k127_2747217_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005374 318.0
HFD2_k127_2747217_4 RHS Repeat - - - 0.000000000000000000000000000000000000000000000000000001855 219.0
HFD2_k127_2747217_5 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000002835 212.0
HFD2_k127_2747217_6 - - - - 0.000000000000000000000000000000000000000000004813 190.0
HFD2_k127_2747217_7 - - - - 0.000000000000000000000000000001111 142.0
HFD2_k127_2747217_8 N-formylglutamate amidohydrolase - - - 0.0000000000000000000000000008816 129.0
HFD2_k127_2747217_9 - - - - 0.0000000000001445 79.0
HFD2_k127_2834031_0 ABC transporter, transmembrane K18890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 640.0
HFD2_k127_2834031_1 ABC transporter, transmembrane K18889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004742 584.0
HFD2_k127_2834031_10 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000003169 269.0
HFD2_k127_2834031_11 Heat shock protein DnaJ domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000003307 230.0
HFD2_k127_2834031_12 Deoxynucleoside kinase K15518 - 2.7.1.113 0.00000000000000000000000000000000000000000000000000000000000003244 227.0
HFD2_k127_2834031_13 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.000000000000000000000000000000000000000000000000000000000002563 237.0
HFD2_k127_2834031_14 HNH nucleases - - - 0.000000000000000000000000000000000000000000000000000000001054 205.0
HFD2_k127_2834031_15 RNA pseudouridylate synthase K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000006689 201.0
HFD2_k127_2834031_16 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000007235 189.0
HFD2_k127_2834031_17 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000004635 156.0
HFD2_k127_2834031_18 nucleotide metabolic process - - - 0.000000000000000000000000000000000000000904 160.0
HFD2_k127_2834031_19 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000000000000000000000000000000008248 145.0
HFD2_k127_2834031_2 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 571.0
HFD2_k127_2834031_20 Acyltransferase family - - - 0.00000000000000000000000000000000001801 150.0
HFD2_k127_2834031_21 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.000000000000000000000000000000008063 132.0
HFD2_k127_2834031_22 Metallo-peptidase family M12 - - - 0.000000000000000000000000000000135 144.0
HFD2_k127_2834031_23 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000004084 119.0
HFD2_k127_2834031_24 von Willebrand factor, type A - - - 0.000000000000000000000003068 113.0
HFD2_k127_2834031_25 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000001583 86.0
HFD2_k127_2834031_27 Putative zinc-finger - - - 0.0004998 52.0
HFD2_k127_2834031_3 PFAM Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 557.0
HFD2_k127_2834031_4 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 456.0
HFD2_k127_2834031_5 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 444.0
HFD2_k127_2834031_6 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 336.0
HFD2_k127_2834031_7 transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 314.0
HFD2_k127_2834031_8 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003762 326.0
HFD2_k127_2834031_9 PFAM KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000002775 266.0
HFD2_k127_2843023_0 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006574 569.0
HFD2_k127_2843023_1 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009667 450.0
HFD2_k127_2847183_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710,K12450 GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 4.2.1.46,4.2.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006206 439.0
HFD2_k127_2847183_1 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744,K09774,K22110 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0009279,GO:0015267,GO:0015288,GO:0015749,GO:0015750,GO:0015751,GO:0015757,GO:0016020,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030312,GO:0030313,GO:0031975,GO:0034219,GO:0044462,GO:0044464,GO:0046323,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:1904659 - 0.0000000000000000000000000000000000000000000000000000000001031 229.0
HFD2_k127_2857318_0 nitrite transmembrane transporter activity - - - 0.0 1011.0
HFD2_k127_2857318_1 PFAM Glucose Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 399.0
HFD2_k127_2857318_11 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000001263 66.0
HFD2_k127_2857318_12 Belongs to the UPF0271 (lamB) family K07160 - - 0.00000007259 53.0
HFD2_k127_2857318_13 endonuclease activity K07451 - - 0.000008418 55.0
HFD2_k127_2857318_14 - - - - 0.00009831 53.0
HFD2_k127_2857318_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 347.0
HFD2_k127_2857318_3 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 335.0
HFD2_k127_2857318_4 copper resistance - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001724 268.0
HFD2_k127_2857318_5 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372,K02567 - - 0.000000000000000000000000000000000000000000000000000000000007707 217.0
HFD2_k127_2857318_6 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000000000000000000000393 204.0
HFD2_k127_2857318_7 translation initiation factor activity K06996 - - 0.00000000000000000000000000000000000000003289 160.0
HFD2_k127_2857318_8 CHRD domain - - - 0.000000000000000002119 91.0
HFD2_k127_2857318_9 serine threonine protein kinase K08884 - 2.7.11.1 0.0000000000000006528 93.0
HFD2_k127_2886471_0 OPT oligopeptide transporter protein - - - 9.108e-270 850.0
HFD2_k127_2886471_1 PFAM NHL repeat containing protein - - - 4.672e-233 755.0
HFD2_k127_2886471_10 Phosphate acetyl/butaryl transferase K00625 - 2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002111 292.0
HFD2_k127_2886471_11 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001004 286.0
HFD2_k127_2886471_12 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000004359 258.0
HFD2_k127_2886471_13 tRNA 3'-trailer cleavage K00784,K01120 - 3.1.26.11,3.1.4.17 0.000000000000000000000000000000000000000000000000000000000000000004969 235.0
HFD2_k127_2886471_14 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000002004 177.0
HFD2_k127_2886471_15 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01945 - 6.3.4.13 0.0000000000000000000000000000000000000001954 171.0
HFD2_k127_2886471_16 Probable zinc-ribbon domain - - - 0.000000000000000000000000000000002754 133.0
HFD2_k127_2886471_17 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000000000000000000000000000004056 131.0
HFD2_k127_2886471_18 Peptidase inhibitor I9 - - - 0.000000000000000000000000000005846 139.0
HFD2_k127_2886471_19 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.000000000000000000000009307 102.0
HFD2_k127_2886471_2 acyl-CoA dehydrogenase activity K09456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 516.0
HFD2_k127_2886471_20 methyltransferase K00568 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.1.1.222,2.1.1.64 0.0000000000000000006268 99.0
HFD2_k127_2886471_22 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000002963 63.0
HFD2_k127_2886471_23 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000002775 60.0
HFD2_k127_2886471_3 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006423 434.0
HFD2_k127_2886471_4 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 361.0
HFD2_k127_2886471_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005595 355.0
HFD2_k127_2886471_6 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004332 342.0
HFD2_k127_2886471_7 COG1228 Imidazolonepropionase and related amidohydrolases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 341.0
HFD2_k127_2886471_8 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 323.0
HFD2_k127_2886471_9 UbiA prenyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006996 300.0
HFD2_k127_293129_0 Sodium:neurotransmitter symporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 550.0
HFD2_k127_293129_1 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 387.0
HFD2_k127_293129_10 Phenylacetic acid catabolic protein K02609 - 1.14.13.149 0.0000000009736 72.0
HFD2_k127_293129_2 Acyl-CoA dehydrogenase, middle domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003503 340.0
HFD2_k127_293129_3 NADH oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 313.0
HFD2_k127_293129_4 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001074 256.0
HFD2_k127_293129_5 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000001186 243.0
HFD2_k127_293129_6 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000001947 237.0
HFD2_k127_293129_7 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000003913 136.0
HFD2_k127_293129_8 - - - - 0.00000000000002256 84.0
HFD2_k127_293129_9 COG1846 Transcriptional regulators - - - 0.00000000000006061 82.0
HFD2_k127_2939839_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 5.859e-304 943.0
HFD2_k127_2939839_1 - - - - 1.16e-257 806.0
HFD2_k127_2939839_10 transposase activity K07483,K07497 - - 0.000000000001819 74.0
HFD2_k127_2939839_11 - - - - 0.00001839 57.0
HFD2_k127_2939839_2 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 397.0
HFD2_k127_2939839_3 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008087 368.0
HFD2_k127_2939839_4 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001787 262.0
HFD2_k127_2939839_5 Carboxylesterase K06999 - - 0.0000000000000000000000000000000000000000000000000000000000000201 223.0
HFD2_k127_2939839_6 phosphatidylcholine synthase activity K01004 - 2.7.8.24 0.0000000000000000000000000000000000000000000000000000000000329 213.0
HFD2_k127_2939839_7 response regulator - - - 0.0000000000000000000000000000000000000000000000000009707 203.0
HFD2_k127_2939839_8 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000002415 188.0
HFD2_k127_2953379_0 FAD linked oxidase domain protein - - - 3.704e-232 735.0
HFD2_k127_2953379_1 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 8.775e-208 679.0
HFD2_k127_2953379_10 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007147 454.0
HFD2_k127_2953379_11 Glycosyl Hydrolase Family 88 K15532 - 3.2.1.172 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 444.0
HFD2_k127_2953379_12 prohibitin homologues K07192 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 441.0
HFD2_k127_2953379_13 transmembrane transporter activity K08191 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 372.0
HFD2_k127_2953379_14 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 387.0
HFD2_k127_2953379_15 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate K01815 - 5.3.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005041 336.0
HFD2_k127_2953379_16 TIGRFAM YihY family protein (not ribonuclease BN) K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007611 304.0
HFD2_k127_2953379_17 Pectate lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000743 320.0
HFD2_k127_2953379_18 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 319.0
HFD2_k127_2953379_19 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 310.0
HFD2_k127_2953379_2 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 5.33e-207 658.0
HFD2_k127_2953379_20 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002866 303.0
HFD2_k127_2953379_21 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000002126 262.0
HFD2_k127_2953379_22 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000142 261.0
HFD2_k127_2953379_23 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000006992 257.0
HFD2_k127_2953379_24 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000009882 246.0
HFD2_k127_2953379_25 Domain of unknown function (DUF4861) - - - 0.000000000000000000000000000000000000000000000000000000000000000008856 239.0
HFD2_k127_2953379_26 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000008241 248.0
HFD2_k127_2953379_27 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000005608 239.0
HFD2_k127_2953379_28 ABC-type multidrug transport system ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000006364 217.0
HFD2_k127_2953379_29 - - - - 0.0000000000000000000000000000000000000000000000000000003454 201.0
HFD2_k127_2953379_3 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009047 616.0
HFD2_k127_2953379_30 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000005628 222.0
HFD2_k127_2953379_31 - - - - 0.00000000000000000000000000000000000000000000000000004796 191.0
HFD2_k127_2953379_32 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000002774 150.0
HFD2_k127_2953379_33 Protein of unknown function (DUF4019) - - - 0.00000000000000000000000000000000123 135.0
HFD2_k127_2953379_34 - - - - 0.0000000000000000006183 97.0
HFD2_k127_2953379_35 Protein of unknown function, DUF255 - - - 0.00000000001731 72.0
HFD2_k127_2953379_36 - - - - 0.00000000002571 67.0
HFD2_k127_2953379_37 Parallel beta-helix repeats - - - 0.000000003578 70.0
HFD2_k127_2953379_38 Domain of unknown function (DUF4388) - - - 0.0000001297 59.0
HFD2_k127_2953379_39 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000006529 59.0
HFD2_k127_2953379_4 Glucuronate isomerase K01812 - 5.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006724 589.0
HFD2_k127_2953379_40 - - - - 0.0001791 53.0
HFD2_k127_2953379_41 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0009288 51.0
HFD2_k127_2953379_5 Belongs to the glycosyl hydrolase 28 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 542.0
HFD2_k127_2953379_6 Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 485.0
HFD2_k127_2953379_7 prohibitin homologues K07192 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004294 490.0
HFD2_k127_2953379_8 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 459.0
HFD2_k127_2953379_9 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004751 456.0
HFD2_k127_2972692_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 7.903e-297 932.0
HFD2_k127_2972692_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.385e-221 695.0
HFD2_k127_2972692_10 Cytochrome c - - - 0.0000000000000000000000000000000001017 144.0
HFD2_k127_2972692_11 transport system, periplasmic component K01989 - - 0.0000000000000001682 94.0
HFD2_k127_2972692_12 Nitrate reductase gamma subunit K00374 - 1.7.5.1 0.000000000001811 78.0
HFD2_k127_2972692_13 transport system, periplasmic component K01989 - - 0.0000000007284 70.0
HFD2_k127_2972692_14 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000184 67.0
HFD2_k127_2972692_15 Belongs to the ABC transporter superfamily K02031,K02032,K13892,K13896 - - 0.00000003215 63.0
HFD2_k127_2972692_2 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 436.0
HFD2_k127_2972692_3 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008078 364.0
HFD2_k127_2972692_4 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003878 387.0
HFD2_k127_2972692_5 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 357.0
HFD2_k127_2972692_6 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007299 324.0
HFD2_k127_2972692_7 PFAM Class III cytochrome C family - - - 0.0000000000000000000000000000000000000000000000002451 193.0
HFD2_k127_2972692_8 Ferrous iron transport protein B K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000604 177.0
HFD2_k127_2972692_9 - - - - 0.000000000000000000000000000000000000008215 165.0
HFD2_k127_3015516_0 Penicillin amidase K07116 - 3.5.1.97 1.96e-240 762.0
HFD2_k127_3015516_1 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 4.298e-220 719.0
HFD2_k127_3015516_10 WD40 domain protein beta Propeller - - - 0.000000000000000000000000000008554 138.0
HFD2_k127_3015516_11 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000001058 122.0
HFD2_k127_3015516_12 PFAM HxlR-like helix-turn-helix - - - 0.000000000000000002326 98.0
HFD2_k127_3015516_13 Response regulator, receiver - - - 0.00000003441 62.0
HFD2_k127_3015516_14 diguanylate cyclase K02488 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 2.7.7.65 0.00001898 55.0
HFD2_k127_3015516_15 TIGRFAM phosphate regulon transcriptional regulatory protein PhoB K07657 - - 0.0005093 50.0
HFD2_k127_3015516_2 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 2.355e-212 677.0
HFD2_k127_3015516_3 Domain of unknown function (DUF4139) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005882 548.0
HFD2_k127_3015516_4 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 557.0
HFD2_k127_3015516_5 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004894 416.0
HFD2_k127_3015516_6 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 398.0
HFD2_k127_3015516_7 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 381.0
HFD2_k127_3015516_8 arylsulfatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 346.0
HFD2_k127_3015516_9 - - - - 0.000000000000000000000000000000000000000005715 162.0
HFD2_k127_3061345_0 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 551.0
HFD2_k127_3061345_1 Belongs to the ALAD family K01698 GO:0000287,GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006179 451.0
HFD2_k127_3061345_10 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000005074 117.0
HFD2_k127_3061345_2 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003605 335.0
HFD2_k127_3061345_3 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004761 290.0
HFD2_k127_3061345_4 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000002818 221.0
HFD2_k127_3061345_5 Cache domain - - - 0.000000000000000000000000000000000000000000000000000000396 214.0
HFD2_k127_3061345_6 DinB family - - - 0.00000000000000000000000000000000000000000000007608 174.0
HFD2_k127_3061345_7 dUTP diphosphatase activity K01520,K13038 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23,4.1.1.36,6.3.2.5 0.00000000000000000000000000000000455 132.0
HFD2_k127_3061345_8 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.00000000000000000000000000000000975 147.0
HFD2_k127_3061345_9 PFAM glycosyl transferase family 39 - - - 0.00000000000000000000000000000006649 146.0
HFD2_k127_3085067_0 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000006502 138.0
HFD2_k127_3085067_1 Fatty acid hydroxylase superfamily K00227 - 1.14.19.20 0.00000000000000000000000006524 118.0
HFD2_k127_3085067_2 - - - - 0.0003006 46.0
HFD2_k127_3085067_3 Vitamin K-dependent gamma-carboxylase - - - 0.0004483 53.0
HFD2_k127_3113515_0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 538.0
HFD2_k127_3157064_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1088.0
HFD2_k127_3157064_1 peptidyl-lysine modification to peptidyl-hypusine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008639 362.0
HFD2_k127_3157064_2 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000004889 195.0
HFD2_k127_3157064_3 - - - - 0.000000000000000001186 99.0
HFD2_k127_316755_0 Polysaccharide biosynthesis protein K02851 - 2.7.8.33,2.7.8.35 2.451e-206 655.0
HFD2_k127_316755_1 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 588.0
HFD2_k127_316755_10 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000005721 60.0
HFD2_k127_316755_11 - - - - 0.0004365 52.0
HFD2_k127_316755_2 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 434.0
HFD2_k127_316755_3 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006843 345.0
HFD2_k127_316755_4 (AIR) carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000705 273.0
HFD2_k127_316755_5 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000002793 211.0
HFD2_k127_316755_6 Protein of unknown function (DUF971) K03593 - - 0.000000000000000000000004429 117.0
HFD2_k127_316755_7 Histone deacetylase domain - - - 0.00000000000000000000001692 114.0
HFD2_k127_316755_8 TIGRFAM TonB K03832 - - 0.000000000000000155 94.0
HFD2_k127_316755_9 BlaR1 peptidase M56 - - - 0.000000000000001951 89.0
HFD2_k127_3169052_0 cell shape determining protein MreB K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 552.0
HFD2_k127_3169052_1 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005318 402.0
HFD2_k127_3169052_2 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005422 302.0
HFD2_k127_3169052_3 peptidyl-prolyl isomerase K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000004497 259.0
HFD2_k127_3169052_4 Rod shape-determining protein MreC K03570 - - 0.0000000000000000000000000000000000000009557 159.0
HFD2_k127_3169052_5 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000007695 125.0
HFD2_k127_3169052_6 FecR protein - - - 0.00000000000000000001916 104.0
HFD2_k127_3169052_7 shape-determining protein MreD K03571 - - 0.00007869 51.0
HFD2_k127_3179393_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.165e-196 619.0
HFD2_k127_3179393_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 602.0
HFD2_k127_3179393_10 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.000000000000000000003753 108.0
HFD2_k127_3179393_11 DoxX K15977 - - 0.0000000000000001434 95.0
HFD2_k127_3179393_12 PAP2 superfamily - - - 0.000000000004131 79.0
HFD2_k127_3179393_13 Iron-sulfur cluster-binding domain K06139 - - 0.000002506 60.0
HFD2_k127_3179393_2 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 297.0
HFD2_k127_3179393_3 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000125 291.0
HFD2_k127_3179393_4 Intracellular protease, PfpI family K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000000000000001866 272.0
HFD2_k127_3179393_5 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000000000001157 250.0
HFD2_k127_3179393_6 - - - - 0.000000000000000000000000000000000000000000000000000000169 205.0
HFD2_k127_3179393_7 Protein serine threonine phosphatase K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000001139 199.0
HFD2_k127_3179393_8 PFAM YbbR family protein - - - 0.0000000000000000000000000000000000004966 154.0
HFD2_k127_3179393_9 - - - - 0.00000000000000000000153 106.0
HFD2_k127_3221464_0 Protein serine threonine phosphatase K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000638 240.0
HFD2_k127_3221464_1 PFAM EAL domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000006489 261.0
HFD2_k127_3221464_10 - - - - 0.0000000000000008575 88.0
HFD2_k127_3221464_11 Forkhead associated domain - - - 0.000000000000578 75.0
HFD2_k127_3221464_12 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K05516 - - 0.0000000009649 68.0
HFD2_k127_3221464_13 Anaphase-promoting complex, cyclosome, subunit 3 - - - 0.0000004074 64.0
HFD2_k127_3221464_14 - - - - 0.000611 46.0
HFD2_k127_3221464_2 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000002521 235.0
HFD2_k127_3221464_3 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000002038 199.0
HFD2_k127_3221464_5 - - - - 0.0000000000000000000000000000000000000001545 164.0
HFD2_k127_3221464_6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.00000000000000000000000000000002864 136.0
HFD2_k127_3221464_7 cheY-homologous receiver domain K07668 - - 0.0000000000000000000000000000006647 125.0
HFD2_k127_3221464_8 Tetratricopeptide repeats - - - 0.000000000000000000000000000002272 138.0
HFD2_k127_3221464_9 Domain of unknown function (DUF4115) K15539 - - 0.000000000000000000000000004053 122.0
HFD2_k127_3239558_0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 1.215e-251 799.0
HFD2_k127_3239558_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 479.0
HFD2_k127_3239558_10 GAF domain - - - 0.00000000000000000000549 98.0
HFD2_k127_3239558_11 Protein of unknown function (DUF2905) - - - 0.0000000000000001579 81.0
HFD2_k127_3239558_2 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 434.0
HFD2_k127_3239558_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 420.0
HFD2_k127_3239558_4 LOR/SDH bifunctional enzyme conserved region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 388.0
HFD2_k127_3239558_5 Belongs to the dCTP deaminase family K01494 GO:0003674,GO:0003824,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005179 316.0
HFD2_k127_3239558_6 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000004791 186.0
HFD2_k127_3239558_7 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000714 153.0
HFD2_k127_3239558_8 negative regulation of transcription, DNA-templated - GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000004216 138.0
HFD2_k127_3239558_9 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000004395 111.0
HFD2_k127_3252594_0 Multicopper oxidase K06324 - 1.16.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 621.0
HFD2_k127_3252594_1 PFAM Glycosyl transferase, family K00756 - 2.4.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009321 502.0
HFD2_k127_3252594_10 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000004568 242.0
HFD2_k127_3252594_11 WYL domain - - - 0.000000000000000000000000000000000000000000000000000000000003787 220.0
HFD2_k127_3252594_12 PFAM EAL domain - - - 0.00000000000000000000000000000000000000000000000000003962 203.0
HFD2_k127_3252594_13 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.000000000000000000000000000000000000000000000002771 184.0
HFD2_k127_3252594_14 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000133 170.0
HFD2_k127_3252594_15 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion K02564 - 3.5.99.6 0.000000000000000000000000000000000000000000008936 181.0
HFD2_k127_3252594_16 Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides K02759,K03478 - 2.7.1.196,2.7.1.205,3.5.1.105 0.0000000000000000000000000000000000000000006461 168.0
HFD2_k127_3252594_17 Cytidine and deoxycytidylate deaminase zinc-binding region K01489 - 3.5.4.5 0.00000000000000000000000000000000000002822 159.0
HFD2_k127_3252594_18 GIY-YIG type nucleases (URI domain) K02342 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391 2.7.7.7 0.00000000000000000000000000000000005818 145.0
HFD2_k127_3252594_19 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000008654 145.0
HFD2_k127_3252594_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003368 492.0
HFD2_k127_3252594_21 - - - - 0.00000000001298 78.0
HFD2_k127_3252594_3 PFAM Na dependent nucleoside transporter K03317 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004921 450.0
HFD2_k127_3252594_4 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003984 459.0
HFD2_k127_3252594_5 Zinc-binding dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004926 385.0
HFD2_k127_3252594_6 PFAM Alcohol dehydrogenase K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 359.0
HFD2_k127_3252594_7 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 315.0
HFD2_k127_3252594_8 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.00000000000000000000000000000000000000000000000000000000000000000000007004 250.0
HFD2_k127_3252594_9 Proline dehydrogenase K00318 GO:0000166,GO:0003674,GO:0003824,GO:0004657,GO:0005488,GO:0006082,GO:0006520,GO:0006560,GO:0006562,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016491,GO:0016645,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 - 0.00000000000000000000000000000000000000000000000000000000000000000002456 247.0
HFD2_k127_3256836_0 amino acid carrier protein K03310 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 572.0
HFD2_k127_3256836_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005303 387.0
HFD2_k127_3256836_2 Beta-lactamase class C - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 313.0
HFD2_k127_3256836_3 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000001767 254.0
HFD2_k127_3256836_4 NUDIX domain - - - 0.000000000000000000000000000000000000000000003323 169.0
HFD2_k127_3256836_6 Peptidase family M48 - - - 0.00000000000000001757 95.0
HFD2_k127_3256836_7 Amidohydrolase family - - - 0.000000000006365 77.0
HFD2_k127_3273926_0 xanthine dehydrogenase activity K04108 - 1.3.7.9 3.026e-312 975.0
HFD2_k127_3273926_1 PFAM peptidase M13 K01415 - 3.4.24.71 9.768e-268 847.0
HFD2_k127_3273926_2 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008637 348.0
HFD2_k127_3273926_3 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000001151 238.0
HFD2_k127_3273926_4 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000007593 222.0
HFD2_k127_3273926_5 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000000000002329 180.0
HFD2_k127_3273926_6 - - - - 0.0000000000000000000000000000000000001718 154.0
HFD2_k127_3273926_7 PFAM regulatory protein TetR K09017 - - 0.00000000000000000000000000002826 129.0
HFD2_k127_3273926_8 Transglycosylase associated protein - - - 0.0000000000000000000201 104.0
HFD2_k127_3273926_9 Periplasmic or secreted lipoprotein - - - 0.000000000001705 78.0
HFD2_k127_3297556_0 Alpha-amylase domain K05343 - 3.2.1.1,5.4.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 514.0
HFD2_k127_3297556_1 Dehydrogenase E1 component K00164 - 1.2.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 432.0
HFD2_k127_3297556_2 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000001277 175.0
HFD2_k127_3297556_3 Cytidylate kinase-like family - - - 0.00000000000000000000000000000000002833 144.0
HFD2_k127_3309179_0 MacB-like periplasmic core domain - - - 4.603e-258 822.0
HFD2_k127_3309179_1 Protein of unknown function (DUF1800) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003812 524.0
HFD2_k127_3309179_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007737 307.0
HFD2_k127_3309179_11 protein).. Source PGD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007618 302.0
HFD2_k127_3309179_12 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000000000000000000000000000000000000000000000000000000001734 247.0
HFD2_k127_3309179_13 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000808 222.0
HFD2_k127_3309179_14 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000000000000000000000000000002083 192.0
HFD2_k127_3309179_15 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain K02488 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 2.7.7.65 0.00000000000000000000000000000000000000000000000000122 201.0
HFD2_k127_3309179_16 Predicted membrane protein (DUF2127) - - - 0.000000000000000000000000000000000000001745 153.0
HFD2_k127_3309179_17 Metallo-peptidase family M12 - - - 0.000000000000000000000000000000000000003749 162.0
HFD2_k127_3309179_18 Transcriptional regulator, Crp Fnr family K01420,K10914 - - 0.000000000000000000000000000000000000006971 157.0
HFD2_k127_3309179_19 cellulase activity K01178,K14645,K18546 - 3.2.1.3 0.000000000000000000000000000007376 139.0
HFD2_k127_3309179_2 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 473.0
HFD2_k127_3309179_20 PFAM yiaA B two helix domain - - - 0.0000000000000000000000000103 113.0
HFD2_k127_3309179_21 Immunity protein 30 - - - 0.0000000000000000000009083 101.0
HFD2_k127_3309179_22 heat shock protein binding K05516,K05801 - - 0.0000000000000000002584 104.0
HFD2_k127_3309179_23 bacterial-type flagellum-dependent cell motility - - - 0.00000000000000001538 99.0
HFD2_k127_3309179_24 Yip1 domain - - - 0.00000000000000003298 91.0
HFD2_k127_3309179_25 Protein of unknown function (DUF1360) - - - 0.00000000000006995 86.0
HFD2_k127_3309179_26 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K05970 - 3.1.1.53 0.00000000004894 77.0
HFD2_k127_3309179_27 Thioredoxin-like - - - 0.0000000004199 61.0
HFD2_k127_3309179_29 Concanavalin A-like lectin/glucanases superfamily - - - 0.00001365 59.0
HFD2_k127_3309179_3 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 443.0
HFD2_k127_3309179_5 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007539 336.0
HFD2_k127_3309179_6 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 322.0
HFD2_k127_3309179_7 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 337.0
HFD2_k127_3309179_8 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 312.0
HFD2_k127_3309179_9 COGs COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 322.0
HFD2_k127_3363859_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009018 522.0
HFD2_k127_3363859_1 TIGRFAM acetaldehyde dehydrogenase (acetylating) K00132 - 1.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 526.0
HFD2_k127_3363859_10 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.00000000000000000000000000000000000000000000001284 174.0
HFD2_k127_3363859_11 BMC K04027 - - 0.00000000000000000000000000000000005128 139.0
HFD2_k127_3363859_12 Protein of unknown function (DUF502) - GO:0003002,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0007275,GO:0007389,GO:0008150,GO:0010051,GO:0010222,GO:0012505,GO:0016020,GO:0016021,GO:0031224,GO:0032501,GO:0032502,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044425,GO:0044444,GO:0044464,GO:0048856 - 0.000000000000000000000000001626 130.0
HFD2_k127_3363859_14 4-amino-4-deoxy-L-arabinose transferase activity K07264 - 2.4.2.43 0.000000000000000001625 100.0
HFD2_k127_3363859_15 Psort location Extracellular, score - - - 0.000000000000000006807 100.0
HFD2_k127_3363859_17 BON domain - - - 0.00000001239 62.0
HFD2_k127_3363859_2 cellulase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 523.0
HFD2_k127_3363859_3 magnesium chelatase, ChlI subunit K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000826 454.0
HFD2_k127_3363859_4 Anion-transporting ATPase K01551 - 3.6.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 381.0
HFD2_k127_3363859_5 Lysin motif K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 306.0
HFD2_k127_3363859_6 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006924 316.0
HFD2_k127_3363859_7 GTP binding K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000103 271.0
HFD2_k127_3363859_8 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000000000000000000000000000000000000001131 198.0
HFD2_k127_3363859_9 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000003121 194.0
HFD2_k127_3545017_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 545.0
HFD2_k127_3545017_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 501.0
HFD2_k127_3545017_10 mttA/Hcf106 family K03116 - - 0.0000000008985 70.0
HFD2_k127_3545017_11 Thioredoxin-like - - - 0.00001257 56.0
HFD2_k127_3545017_2 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 490.0
HFD2_k127_3545017_3 tRNA processing K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000715 237.0
HFD2_k127_3545017_4 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000001011 172.0
HFD2_k127_3545017_5 membrane - - - 0.000000000000000000000000000000001329 138.0
HFD2_k127_3545017_6 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000006204 134.0
HFD2_k127_3545017_7 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000005598 92.0
HFD2_k127_3545017_8 WD40-like Beta Propeller Repeat K03641 - - 0.00000000000002572 83.0
HFD2_k127_3545017_9 lysine biosynthesis protein LysW K05826 - - 0.0000000003016 63.0
HFD2_k127_3549711_0 dna ligase K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 311.0
HFD2_k127_3549711_1 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000001309 192.0
HFD2_k127_3549711_2 - - - - 0.00000000000000000000000000000000000000000002371 180.0
HFD2_k127_3549711_3 - - - - 0.00000002929 58.0
HFD2_k127_3557204_0 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003512 500.0
HFD2_k127_3557204_1 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 347.0
HFD2_k127_3557204_2 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000001335 231.0
HFD2_k127_3557204_3 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000001436 126.0
HFD2_k127_3606260_0 GGDEF domain K13243 - 3.1.4.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008809 423.0
HFD2_k127_3606260_1 Sel1 domain protein repeat-containing protein K07126 - - 0.000000000000000000000000000000000000000000000000000000000000000003359 241.0
HFD2_k127_3606260_2 EamA-like transporter family - - - 0.00000000000000000000000000000000000000004742 162.0
HFD2_k127_3606260_3 peptidase - - - 0.000000000000000000000000004094 123.0
HFD2_k127_3606260_4 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 - 6.1.1.12 0.000000000000201 70.0
HFD2_k127_3610127_0 abc transporter atp-binding protein K06147 - - 8.259e-286 899.0
HFD2_k127_3610127_1 TonB-dependent Receptor Plug - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 593.0
HFD2_k127_3610127_2 Cytidine monophosphokinase K00876 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 0.000000000000000000000000000000000000000000000000000000000000000003059 231.0
HFD2_k127_3610127_3 HAD-hyrolase-like - - - 0.000000000000000000000000000000000000000000000000000000000000000102 252.0
HFD2_k127_3610127_4 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811,K09812 GO:0000910,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006928,GO:0007049,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008356,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0016020,GO:0016021,GO:0016043,GO:0019221,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0023052,GO:0030312,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0032153,GO:0032506,GO:0034097,GO:0040007,GO:0040011,GO:0042173,GO:0042221,GO:0043207,GO:0043937,GO:0043938,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0048870,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070098,GO:0070297,GO:0070887,GO:0071310,GO:0071345,GO:0071840,GO:0071944,GO:0071976,GO:0090529,GO:1902531 - 0.00000000000000000000000000000000000000000000000000007122 197.0
HFD2_k127_3610127_5 - - - - 0.0000000000000000000000000000001247 142.0
HFD2_k127_3610127_6 Carboxypeptidase regulatory-like domain - - - 0.0000007993 63.0
HFD2_k127_361186_0 beta-galactosidase activity K15855 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005576,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044238,GO:0071704,GO:1901575 3.2.1.165 5.033e-287 927.0
HFD2_k127_361186_1 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 571.0
HFD2_k127_361186_10 Tetratricopeptide repeat - - - 0.00000153 62.0
HFD2_k127_361186_11 COG0457 FOG TPR repeat - - - 0.00000221 59.0
HFD2_k127_361186_2 Amino acid permease K03294,K19540 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006040,GO:0006082,GO:0006520,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008152,GO:0008509,GO:0008514,GO:0009056,GO:0009063,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0016054,GO:0019752,GO:0022804,GO:0022857,GO:0030389,GO:0030392,GO:0030393,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0046348,GO:0046395,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098656,GO:1901135,GO:1901136,GO:1901281,GO:1901564,GO:1901565,GO:1901575,GO:1902475,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 544.0
HFD2_k127_361186_3 lipoprotein localization to outer membrane K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 426.0
HFD2_k127_361186_4 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003884 357.0
HFD2_k127_361186_5 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 324.0
HFD2_k127_361186_6 PFAM YdjC family protein K03478 - 3.5.1.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000000405 274.0
HFD2_k127_361186_7 permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001458 277.0
HFD2_k127_361186_8 pfam rok - - - 0.000000000000000000000000000000000000000000000000000001636 207.0
HFD2_k127_361186_9 repeat-containing protein - - - 0.0000000000000000002948 103.0
HFD2_k127_3616595_0 Male sterility protein K15891 - 1.1.1.354 0.0000000000000000000000000000000000000000000000000000000000000000000000223 250.0
HFD2_k127_3616595_1 PFAM Integral membrane protein DUF92 - GO:0005575,GO:0016020 - 0.00000000000000000000000000000000000008106 158.0
HFD2_k127_3616595_2 TIGRFAM Bacteriochlorophyll chlorophyll synthetase K04040 - 2.5.1.133,2.5.1.62 0.000000000000000000002748 110.0
HFD2_k127_3616595_3 Dolichol kinase K18678 GO:0003674,GO:0003824,GO:0006066,GO:0006629,GO:0006720,GO:0006721,GO:0006766,GO:0006775,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009987,GO:0010189,GO:0010276,GO:0016101,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017144,GO:0018130,GO:0033306,GO:0034308,GO:0042360,GO:0042362,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901576,GO:1901615,GO:1901617,GO:1903173 2.7.1.182 0.0000007701 61.0
HFD2_k127_363682_0 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 1.056e-204 650.0
HFD2_k127_363682_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 1.643e-202 639.0
HFD2_k127_363682_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008294 550.0
HFD2_k127_363682_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 544.0
HFD2_k127_363682_4 Phosphoesterase, PA-phosphatase related protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000002999 241.0
HFD2_k127_363682_5 Tautomerase enzyme - - - 0.0000000000000000000000000000000003239 134.0
HFD2_k127_363682_6 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000009856 115.0
HFD2_k127_363682_7 Protein of unknown function (DUF2911) - - - 0.00000000000003159 87.0
HFD2_k127_3646963_0 GHMP kinases C terminal K07031 - 2.7.1.168 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007292 374.0
HFD2_k127_3646963_1 D-glycero-D-manno-heptose 7-phosphate metabolic process K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000001538 258.0
HFD2_k127_3646963_2 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00966 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000006485 226.0
HFD2_k127_3646963_3 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000494 82.0
HFD2_k127_3735427_0 Glycoside hydrolase family 44 - - - 1.028e-235 742.0
HFD2_k127_3735427_1 Peptidase, M16 K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 531.0
HFD2_k127_3735427_2 peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004537 438.0
HFD2_k127_3735427_3 Peptidase, M16 K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000396 360.0
HFD2_k127_3735427_4 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.0000000000000000000000000000000000000000000000275 178.0
HFD2_k127_3735427_5 Putative molybdenum carrier - - - 0.0000000000000000000000000000000000000000000005779 171.0
HFD2_k127_3735427_6 Endonuclease Exonuclease Phosphatase - - - 0.0000000000000000000000000000000000008345 149.0
HFD2_k127_3735427_7 PFAM Thioredoxin domain K03671 - - 0.000000000000000000000001596 120.0
HFD2_k127_3735427_9 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.0007563 48.0
HFD2_k127_3739358_0 WD40-like Beta Propeller Repeat - - - 1.345e-238 766.0
HFD2_k127_3739358_1 ATPase family associated with various cellular activities (AAA) K06027 - 3.6.4.6 2.681e-228 717.0
HFD2_k127_3739358_10 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000007495 202.0
HFD2_k127_3739358_11 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine K04068 - 1.97.1.4 0.0000000000000000000000000000000000000000000000002923 182.0
HFD2_k127_3739358_12 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000001357 142.0
HFD2_k127_3739358_13 - - - - 0.0000000000000000000000000000000000733 140.0
HFD2_k127_3739358_14 Tetratricopeptide repeat - - - 0.000000000000000000000000000000004955 148.0
HFD2_k127_3739358_15 - - - - 0.0000000000000004806 93.0
HFD2_k127_3739358_16 Surface antigen - - - 0.00000000000008805 86.0
HFD2_k127_3739358_17 PFAM membrane protein of K08972 - - 0.0000000000001726 82.0
HFD2_k127_3739358_18 Anti-sigma-K factor rskA - - - 0.00000000005136 77.0
HFD2_k127_3739358_19 Protein of unknown function (DUF2997) - - - 0.0000002969 55.0
HFD2_k127_3739358_2 Phosphoenolpyruvate phosphomutase K01637 - 4.1.3.1 2.503e-217 682.0
HFD2_k127_3739358_20 Protein of unknown function (DUF1257) - - - 0.000003869 56.0
HFD2_k127_3739358_21 Domain of unknown function (DUF4412) - - - 0.00000403 57.0
HFD2_k127_3739358_3 Pfam:DUF955 K07110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 572.0
HFD2_k127_3739358_4 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 534.0
HFD2_k127_3739358_5 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 481.0
HFD2_k127_3739358_6 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008836 391.0
HFD2_k127_3739358_7 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002167 273.0
HFD2_k127_3739358_8 ggdef domain - - - 0.000000000000000000000000000000000000000000000000000000000000008252 233.0
HFD2_k127_3739358_9 hydrolase K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000006214 228.0
HFD2_k127_3762614_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 443.0
HFD2_k127_3762614_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 435.0
HFD2_k127_3762614_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.0000000000001556 83.0
HFD2_k127_3762614_3 Tetratricopeptide repeat - - - 0.000002199 53.0
HFD2_k127_3762652_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 522.0
HFD2_k127_3762652_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 430.0
HFD2_k127_3762652_2 Tetratricopeptide repeat - - - 0.000002199 53.0
HFD2_k127_3774092_0 to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003376 443.0
HFD2_k127_3774092_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005697 390.0
HFD2_k127_3774092_2 Mur ligase family, catalytic domain K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 320.0
HFD2_k127_3774092_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000002471 77.0
HFD2_k127_3774092_4 PASTA domain K03587 - 3.4.16.4 0.00000002 62.0
HFD2_k127_378520_0 COG3209 Rhs family protein - - - 0.0 1722.0
HFD2_k127_378520_1 Peptidoglycan-binding domain 1 protein - - - 0.0 1457.0
HFD2_k127_378520_10 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 301.0
HFD2_k127_378520_11 PFAM AAA ATPase central domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003549 295.0
HFD2_k127_378520_12 enzyme related to lactoylglutathione lyase K06996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003642 252.0
HFD2_k127_378520_13 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001276 260.0
HFD2_k127_378520_14 Protoporphyrinogen oxidase - - - 0.0000000000000000000000000000000000000000000000000000000002848 230.0
HFD2_k127_378520_15 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000001175 210.0
HFD2_k127_378520_16 Methionine biosynthesis protein MetW K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000004264 216.0
HFD2_k127_378520_17 Cytochrome P460 - - - 0.00000000000000000000000000000000000000000000000000000006193 207.0
HFD2_k127_378520_18 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000001595 199.0
HFD2_k127_378520_19 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000000000002471 194.0
HFD2_k127_378520_2 Carbamoyltransferase C-terminus K00612 - - 7.31e-236 749.0
HFD2_k127_378520_20 LD-carboxypeptidase K01297 - 3.4.17.13 0.00000000000000000000000000000000000000000000000000008055 195.0
HFD2_k127_378520_21 dTDP-4-dehydrorhamnose reductase K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000002326 184.0
HFD2_k127_378520_22 TonB-dependent receptor K02014 - - 0.0000000000000000000000000000000000000000003454 181.0
HFD2_k127_378520_23 DNA polymerase III, delta subunit, C terminal K02341 - 2.7.7.7 0.000000000000000000000000000000000000000008368 177.0
HFD2_k127_378520_24 - - - - 0.00000000000000000000000000000000000364 145.0
HFD2_k127_378520_25 DNA-templated transcription, initiation K02405 - - 0.00000000000000000000000000000000005128 156.0
HFD2_k127_378520_26 histone H2A K63-linked ubiquitination K10914 - - 0.000000000000000000000000000000001342 150.0
HFD2_k127_378520_27 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000007657 118.0
HFD2_k127_378520_28 Hfq protein - - - 0.0000000000000000000000000001068 131.0
HFD2_k127_378520_29 - - - - 0.00000000000000006872 94.0
HFD2_k127_378520_3 hydrolase activity, acting on ester bonds K01253,K21159 - 3.3.2.9 4.321e-214 685.0
HFD2_k127_378520_30 bacterial OsmY and nodulation domain - - - 0.0000000000000004684 85.0
HFD2_k127_378520_31 COG1520 FOG WD40-like repeat - - - 0.0000000000002563 83.0
HFD2_k127_378520_33 - - - - 0.0000000003574 73.0
HFD2_k127_378520_34 acetyltransferase - - - 0.0000000005524 70.0
HFD2_k127_378520_35 Belongs to the helicase family. UvrD subfamily K03657 - 3.6.4.12 0.00001698 54.0
HFD2_k127_378520_4 PFAM Peptidase family M20 M25 M40 K01436 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 498.0
HFD2_k127_378520_5 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 510.0
HFD2_k127_378520_6 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 490.0
HFD2_k127_378520_7 Mur ligase middle domain K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007885 420.0
HFD2_k127_378520_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 398.0
HFD2_k127_378520_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 323.0
HFD2_k127_3803771_0 PFAM peptidase M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 589.0
HFD2_k127_3803771_1 Pfam:DUF2029 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006676 391.0
HFD2_k127_3803771_10 - - - - 0.000000000000000000000009932 114.0
HFD2_k127_3803771_11 Psort location CytoplasmicMembrane, score 10.00 - - - 0.00000000009599 75.0
HFD2_k127_3803771_2 ERAP1-like C-terminal domain K01256,K01263 - 3.4.11.14,3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 366.0
HFD2_k127_3803771_3 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006622 355.0
HFD2_k127_3803771_4 Aldo Keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 347.0
HFD2_k127_3803771_5 Pfam Transposase IS66 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 349.0
HFD2_k127_3803771_6 NmrA-like family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000001216 210.0
HFD2_k127_3803771_7 3-demethylubiquinone-9 3-methyltransferase K04750 - - 0.00000000000000000000000000000000002716 139.0
HFD2_k127_3803771_8 FMN binding K03612 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000003732 120.0
HFD2_k127_3803771_9 PFAM RNP-1 like RNA-binding protein - - - 0.00000000000000000000000003022 113.0
HFD2_k127_3829511_0 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000001337 145.0
HFD2_k127_3829511_1 cell redox homeostasis - - - 0.0000000000000000000000000000008402 130.0
HFD2_k127_3829511_2 Transcriptional regulator K07669 - - 0.00000000000000000000002693 108.0
HFD2_k127_3829511_3 ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component K02004 - - 0.000000000000000001659 92.0
HFD2_k127_3837566_0 Ammonium Transporter K03320 - - 2.251e-196 620.0
HFD2_k127_3837566_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000009165 253.0
HFD2_k127_3837566_2 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000000000000007733 202.0
HFD2_k127_3880700_0 Biotin carboxylase K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 589.0
HFD2_k127_3880700_1 Secretin and TonB N terminus short domain K02666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 430.0
HFD2_k127_3880700_10 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000000000343 154.0
HFD2_k127_3880700_11 Methyltransferase domain - - - 0.0000000000000000000000000000000000003554 153.0
HFD2_k127_3880700_12 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000000000004757 157.0
HFD2_k127_3880700_13 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.00000000000000000000000000003328 118.0
HFD2_k127_3880700_14 Pilus assembly protein, PilO K02664 - - 0.000000000000000000000000000388 121.0
HFD2_k127_3880700_15 Bacterial membrane protein YfhO - - - 0.00000000000000000000000001465 127.0
HFD2_k127_3880700_17 Tetratricopeptide repeat - - - 0.00000000002376 76.0
HFD2_k127_3880700_18 Fimbrial assembly protein (PilN) K02663 - - 0.0000000001558 72.0
HFD2_k127_3880700_2 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 362.0
HFD2_k127_3880700_20 Roadblock/LC7 domain - - - 0.000001796 54.0
HFD2_k127_3880700_3 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004029 323.0
HFD2_k127_3880700_4 phosphatase activity K01589,K01955,K07025,K16181 - 6.3.4.18,6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004765 342.0
HFD2_k127_3880700_5 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 319.0
HFD2_k127_3880700_6 WbqC-like protein family - - - 0.000000000000000000000000000000000000000000000000000000001768 211.0
HFD2_k127_3880700_7 Nodulation protein S (NodS) - - - 0.000000000000000000000000000000000000000000000000002209 203.0
HFD2_k127_3880700_8 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000008752 166.0
HFD2_k127_3880700_9 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.0000000000000000000000000000000000000003029 154.0
HFD2_k127_3932313_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000001352 269.0
HFD2_k127_3932313_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003713 247.0
HFD2_k127_3941204_0 - - - - 0.00000000000000000000000000000000003099 153.0
HFD2_k127_3941204_1 Conserved repeat domain - - - 0.00000004093 66.0
HFD2_k127_3950048_0 PFAM PrkA serine kinase K07180 - - 0.0 1468.0
HFD2_k127_3950048_1 DNA helicase K03654 - 3.6.4.12 3.205e-234 741.0
HFD2_k127_3950048_2 XdhC and CoxI family K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000003853 241.0
HFD2_k127_3950048_3 cellulase activity - - - 0.00000000000000000000000000000000000000000000000001457 208.0
HFD2_k127_3950048_4 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000005935 189.0
HFD2_k127_3950048_5 - - - - 0.0000000000000000000000000000000001002 154.0
HFD2_k127_3950048_6 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01219 - 3.2.1.81 0.00000000000000000000000000002452 137.0
HFD2_k127_3950048_7 Selenium-dependent molybdenum hydroxylase system protein, YqeB family K07402 - - 0.0000000000000000000000001447 116.0
HFD2_k127_3950048_8 Involved in chromosome partitioning - - - 0.000000000000000000004458 108.0
HFD2_k127_397491_0 formate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003679 318.0
HFD2_k127_397491_1 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000000000003387 232.0
HFD2_k127_397491_2 recombinase activity - - - 0.000000001128 61.0
HFD2_k127_4009734_0 Belongs to the enoyl-CoA hydratase isomerase family K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 590.0
HFD2_k127_4009734_1 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000001685 98.0
HFD2_k127_4038663_0 Type II/IV secretion system protein K02454,K02652 - - 1.993e-241 768.0
HFD2_k127_4038663_1 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 4.678e-209 684.0
HFD2_k127_4038663_10 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007873 335.0
HFD2_k127_4038663_11 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000424 318.0
HFD2_k127_4038663_12 Oxidoreductase family, C-terminal alpha beta domain K16043 - 1.1.1.370 0.00000000000000000000000000000000000000000000000000000000000000000000000000002638 285.0
HFD2_k127_4038663_13 Protein of unknown function (DUF1343) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006715 288.0
HFD2_k127_4038663_14 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001345 265.0
HFD2_k127_4038663_15 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852,K00856,K10710,K22026 - 2.7.1.15,2.7.1.20,2.7.1.213,2.7.1.218,2.7.1.73 0.0000000000000000000000000000000000000000000002216 190.0
HFD2_k127_4038663_16 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07669 - - 0.00000000000000000000000000000000000000000002918 169.0
HFD2_k127_4038663_18 His Kinase A (phospho-acceptor) domain K02484,K07645 - 2.7.13.3 0.000000000000000000000000000001028 137.0
HFD2_k127_4038663_19 Protein of unknown function (DUF2384) - - - 0.00000000000000000000000000008736 120.0
HFD2_k127_4038663_2 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 1.053e-203 666.0
HFD2_k127_4038663_20 Peptidase family M50 - - - 0.000000000000000000000000002137 121.0
HFD2_k127_4038663_22 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000002052 128.0
HFD2_k127_4038663_23 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.000000000000000000000007786 109.0
HFD2_k127_4038663_24 Outer membrane efflux protein K15725 - - 0.00000000000000000003897 104.0
HFD2_k127_4038663_25 SdiA-regulated - - - 0.0000000000009954 82.0
HFD2_k127_4038663_26 Tetratricopeptide repeat - - - 0.000000000002445 80.0
HFD2_k127_4038663_27 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000002605 72.0
HFD2_k127_4038663_28 serine-type endopeptidase activity - - - 0.00000000216 71.0
HFD2_k127_4038663_29 Transglycosylase associated protein - - - 0.000006201 51.0
HFD2_k127_4038663_3 transmembrane transporter activity K03296 - - 2.568e-197 655.0
HFD2_k127_4038663_31 E3 ubiquitin-protein ligase RNF170-like K15707 GO:0007275,GO:0008150,GO:0009790,GO:0009792,GO:0032501,GO:0032502,GO:0043009,GO:0048856 2.3.2.27 0.00001324 50.0
HFD2_k127_4038663_4 Sugar phosphate permease K02445 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004671 526.0
HFD2_k127_4038663_5 purine nucleotide biosynthetic process K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 377.0
HFD2_k127_4038663_6 KduI/IolB family K03337 - 5.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005866 363.0
HFD2_k127_4038663_7 Sodium:solute symporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 371.0
HFD2_k127_4038663_8 Type ii and iii secretion system protein K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 354.0
HFD2_k127_4038663_9 Male sterility protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000313 329.0
HFD2_k127_4052345_0 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004946 431.0
HFD2_k127_4052345_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 392.0
HFD2_k127_4052345_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 366.0
HFD2_k127_4052345_3 Dehydratase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 372.0
HFD2_k127_4052345_4 abc transporter atp-binding protein K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003691 334.0
HFD2_k127_4052345_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 327.0
HFD2_k127_4052345_6 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000003538 218.0
HFD2_k127_4052345_7 PBS lyase - - - 0.0000000004585 68.0
HFD2_k127_4052345_8 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.000004675 49.0
HFD2_k127_4076190_0 Dienelactone hydrolase family - - - 0.0 1204.0
HFD2_k127_4076190_1 Acetolactate synthase K00156,K01652 - 1.2.5.1,2.2.1.6 2.234e-249 781.0
HFD2_k127_4076190_10 Cell division ATP-binding protein ftsE K09811,K09812 GO:0000166,GO:0000287,GO:0000910,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0007049,GO:0008144,GO:0008150,GO:0008356,GO:0009898,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019897,GO:0019898,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0030145,GO:0030554,GO:0031234,GO:0032153,GO:0032506,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042173,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043937,GO:0043938,GO:0044085,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1902531 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 301.0
HFD2_k127_4076190_11 eRF1 domain 3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 297.0
HFD2_k127_4076190_12 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002923 286.0
HFD2_k127_4076190_13 GDSL-like Lipase/Acylhydrolase family K10804 - 3.1.1.5 0.000000000000000000000000000000000000000000000000000000000002667 216.0
HFD2_k127_4076190_14 PFAM Alpha beta hydrolase K07019 - - 0.000000000000000000000000000000000000000000003951 181.0
HFD2_k127_4076190_15 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00847,K00852,K00874 - 2.7.1.15,2.7.1.4,2.7.1.45 0.000000000000000000000000000000000000000002159 178.0
HFD2_k127_4076190_16 Protein of unknown function (DUF1304) K08987 - - 0.0000000000000000000000000000000000009591 144.0
HFD2_k127_4076190_17 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000005017 145.0
HFD2_k127_4076190_18 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.00000000000000000000000000000007453 146.0
HFD2_k127_4076190_19 cell redox homeostasis - - - 0.00000000000000000000000000000254 128.0
HFD2_k127_4076190_2 Proposed role in polysaccahride synthesis K07077 - - 4.691e-244 764.0
HFD2_k127_4076190_20 Transcriptional regulator K07669 - - 0.000000000000000000001124 104.0
HFD2_k127_4076190_22 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.000000000002201 81.0
HFD2_k127_4076190_23 Protein of unknown function (DUF429) - - - 0.000000000002941 80.0
HFD2_k127_4076190_24 PilZ domain - - - 0.000000002139 63.0
HFD2_k127_4076190_25 Cytidine monophosphokinase K00876 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 0.00009551 44.0
HFD2_k127_4076190_3 malic protein domain protein K00027 - 1.1.1.38 6.252e-202 657.0
HFD2_k127_4076190_4 Glutamine amidotransferases class-II K00764 - 2.4.2.14 1.664e-198 629.0
HFD2_k127_4076190_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 558.0
HFD2_k127_4076190_6 cellulase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 495.0
HFD2_k127_4076190_7 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 488.0
HFD2_k127_4076190_8 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 364.0
HFD2_k127_4076190_9 Glycogen debranching enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003127 324.0
HFD2_k127_4171666_0 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 381.0
HFD2_k127_4171666_1 Glycosyl transferase family group 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 357.0
HFD2_k127_4171666_10 Belongs to the glycosyltransferase 26 family K05946 - 2.4.1.187 0.0000000000000000000000000000000000000000000000000592 188.0
HFD2_k127_4171666_11 deacetylase - - - 0.00000000000000000000000000000000000000005042 165.0
HFD2_k127_4171666_12 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000003034 158.0
HFD2_k127_4171666_13 Methyltransferase FkbM domain - - - 0.000000000000000000000000000000000005207 156.0
HFD2_k127_4171666_14 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000004439 139.0
HFD2_k127_4171666_15 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.000000000000000000000000000000215 141.0
HFD2_k127_4171666_16 Pfam Glycosyl transferase family 2 K16556 - - 0.000000000000000005863 95.0
HFD2_k127_4171666_2 NmrA-like family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 344.0
HFD2_k127_4171666_3 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006794 327.0
HFD2_k127_4171666_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004333 296.0
HFD2_k127_4171666_5 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005097 253.0
HFD2_k127_4171666_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000126 233.0
HFD2_k127_4171666_7 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000000000000000000000000000000000001154 228.0
HFD2_k127_4171666_8 O-antigen ligase like membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000004462 229.0
HFD2_k127_4171666_9 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000009192 206.0
HFD2_k127_4215272_0 PFAM glutamine synthetase catalytic region K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 594.0
HFD2_k127_4215272_1 Aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 557.0
HFD2_k127_4215272_10 transglycosylase associated protein - - - 0.00000000000000008942 93.0
HFD2_k127_4215272_2 COG0534 Na -driven multidrug efflux pump K03327 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008704 496.0
HFD2_k127_4215272_3 alcohol dehydrogenase K13954 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 430.0
HFD2_k127_4215272_4 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002034 265.0
HFD2_k127_4215272_5 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000005464 248.0
HFD2_k127_4215272_6 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000000000000000000002509 202.0
HFD2_k127_4215272_7 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.000000000000000000000000000000000000000000004575 176.0
HFD2_k127_4215272_8 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000008388 105.0
HFD2_k127_4215272_9 - - - - 0.00000000000000006784 86.0
HFD2_k127_4217499_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 2.483e-318 987.0
HFD2_k127_4217499_1 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 3.48e-286 911.0
HFD2_k127_4217499_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 9.365e-254 794.0
HFD2_k127_4217499_3 Amino acid permease - - - 1.4e-205 656.0
HFD2_k127_4217499_4 protein histidine kinase activity K11383 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003464 463.0
HFD2_k127_4217499_5 response regulator K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009111 280.0
HFD2_k127_4217499_6 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000001361 249.0
HFD2_k127_4217499_7 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000000162 219.0
HFD2_k127_4217499_8 phosphorelay signal transduction system K02490 - - 0.00000000000000000000000000000000000006154 163.0
HFD2_k127_4217499_9 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.00000000001156 69.0
HFD2_k127_424307_0 LytB protein K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007627 455.0
HFD2_k127_424307_1 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.0000000000000000000000000000000000000000002273 165.0
HFD2_k127_4248427_0 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 436.0
HFD2_k127_4248427_1 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 337.0
HFD2_k127_4248427_2 adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004602 323.0
HFD2_k127_4248427_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000004694 152.0
HFD2_k127_4248427_4 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.000000000000000000000000000000007097 138.0
HFD2_k127_4260927_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000001576 213.0
HFD2_k127_4260927_1 binds to the 23S rRNA K02939 - - 0.000000000000000000000000000000000000000002063 163.0
HFD2_k127_4260927_2 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000002078 106.0
HFD2_k127_4260927_3 Predicted membrane protein (DUF2232) - - - 0.0000000001016 72.0
HFD2_k127_4260927_4 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000006808 53.0
HFD2_k127_4277522_0 nickel-dependent hydrogenase, large subunit K06281 - 1.12.99.6 3.242e-281 872.0
HFD2_k127_4277522_1 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 6.601e-263 842.0
HFD2_k127_4277522_10 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 382.0
HFD2_k127_4277522_11 PFAM Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 350.0
HFD2_k127_4277522_12 TIGRFAM Hydrogenase accessory protein HypB K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007713 332.0
HFD2_k127_4277522_13 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 318.0
HFD2_k127_4277522_14 YwiC-like protein - - - 0.00000000000000000000000000000000000000000000000001564 189.0
HFD2_k127_4277522_15 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000001564 194.0
HFD2_k127_4277522_16 PFAM peptidase M52 hydrogen uptake protein K03605 - - 0.00000000000000000000000000000000000000000000002705 176.0
HFD2_k127_4277522_18 Vitamin K epoxide reductase family - - - 0.0000000000000000000000000000000000009332 159.0
HFD2_k127_4277522_19 Autotransporter beta-domain - - - 0.000000000000000000000000000000000157 148.0
HFD2_k127_4277522_2 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 - 1.2.7.11,1.2.7.3 5.725e-238 750.0
HFD2_k127_4277522_20 protein histidine kinase activity K06375 - - 0.0000000000000000000000000000004636 134.0
HFD2_k127_4277522_21 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000000001183 137.0
HFD2_k127_4277522_22 Metallo-peptidase family M12 - - - 0.00000000000000000000000000002379 132.0
HFD2_k127_4277522_23 carbon dioxide binding K04653,K04654 - - 0.0000000000000000000000000001589 134.0
HFD2_k127_4277522_24 Cytochrome C biogenesis protein transmembrane region - - - 0.00000000000000000000003161 114.0
HFD2_k127_4277522_25 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000004243 113.0
HFD2_k127_4277522_26 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000000001355 109.0
HFD2_k127_4277522_27 phosphorelay sensor kinase activity - - - 0.0000000000000000008204 101.0
HFD2_k127_4277522_28 Universal stress protein family - - - 0.000000000000001028 91.0
HFD2_k127_4277522_29 BON domain - - - 0.0000000000005553 73.0
HFD2_k127_4277522_3 R3H domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005279 585.0
HFD2_k127_4277522_30 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000004424 76.0
HFD2_k127_4277522_31 Universal stress protein - - - 0.0000000002953 71.0
HFD2_k127_4277522_34 Belongs to the universal stress protein A family - - - 0.0004779 51.0
HFD2_k127_4277522_4 response regulator K02481,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005796 526.0
HFD2_k127_4277522_5 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01667 - 4.1.99.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 524.0
HFD2_k127_4277522_6 Belongs to the HypD family K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006739 496.0
HFD2_k127_4277522_7 hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 496.0
HFD2_k127_4277522_8 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 453.0
HFD2_k127_4277522_9 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004726 442.0
HFD2_k127_428080_0 Uncharacterized protein family (UPF0051) K09014 - - 3.141e-269 833.0
HFD2_k127_428080_1 Large extracellular alpha-helical protein K06894 - - 1.988e-256 861.0
HFD2_k127_428080_10 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 433.0
HFD2_k127_428080_11 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004258 460.0
HFD2_k127_428080_12 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006332 411.0
HFD2_k127_428080_13 amino acid K03294,K13868 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005999 398.0
HFD2_k127_428080_14 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 376.0
HFD2_k127_428080_15 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008365 391.0
HFD2_k127_428080_16 TIGRFAM FeS assembly ATPase SufC K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 384.0
HFD2_k127_428080_17 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 365.0
HFD2_k127_428080_18 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009824 340.0
HFD2_k127_428080_19 K transport systems K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003886 337.0
HFD2_k127_428080_2 AMP-binding enzyme K00666 - - 1.108e-232 755.0
HFD2_k127_428080_20 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008643 339.0
HFD2_k127_428080_21 Uncharacterized protein family (UPF0051) K09015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 342.0
HFD2_k127_428080_22 PFAM peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 349.0
HFD2_k127_428080_23 oxidase, subunit K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 324.0
HFD2_k127_428080_24 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 331.0
HFD2_k127_428080_25 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001532 276.0
HFD2_k127_428080_26 Domain of unknown function (DUF1287) K09974 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001775 249.0
HFD2_k127_428080_27 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000002728 228.0
HFD2_k127_428080_28 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000001924 223.0
HFD2_k127_428080_29 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000000000000000000000000000004163 217.0
HFD2_k127_428080_3 Pyridoxal-dependent decarboxylase conserved domain K01593,K01634 - 4.1.1.105,4.1.1.28,4.1.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 548.0
HFD2_k127_428080_30 Enoyl-CoA hydratase/isomerase K01715,K07537 - 4.2.1.100,4.2.1.17 0.00000000000000000000000000000000000000000000000000000000007436 214.0
HFD2_k127_428080_31 PFAM Appr-1-p processing domain protein - - - 0.00000000000000000000000000000000000000000000000000001373 195.0
HFD2_k127_428080_32 TIGRFAM FeS assembly SUF system protein SufT - - - 0.00000000000000000000000000000000000000000000000000005842 193.0
HFD2_k127_428080_33 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000001483 212.0
HFD2_k127_428080_34 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000000000000000000000000006923 204.0
HFD2_k127_428080_35 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000005785 183.0
HFD2_k127_428080_36 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000001637 198.0
HFD2_k127_428080_37 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000000000000000003521 196.0
HFD2_k127_428080_38 Belongs to the MtfA family K09933 - - 0.00000000000000000000000000000000000000000000002456 181.0
HFD2_k127_428080_39 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000000000000001053 189.0
HFD2_k127_428080_4 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 556.0
HFD2_k127_428080_40 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000001157 171.0
HFD2_k127_428080_41 Methyltransferase domain - - - 0.000000000000000000000000000000000000000001416 165.0
HFD2_k127_428080_42 carboxylic acid catabolic process K01736 - 4.2.3.5 0.0000000000000000000000000000000000000007557 158.0
HFD2_k127_428080_43 2 iron, 2 sulfur cluster binding - - - 0.000000000000000000000000000000000000001046 153.0
HFD2_k127_428080_44 S1/P1 Nuclease - - - 0.000000000000000000000000000000000000004169 169.0
HFD2_k127_428080_45 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000002747 167.0
HFD2_k127_428080_46 EVE domain - - - 0.0000000000000000000000000000000000009226 143.0
HFD2_k127_428080_47 Stage II sporulation protein E K07315 - 3.1.3.3 0.000000000000000000000000000000000001489 156.0
HFD2_k127_428080_48 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000000000000001192 149.0
HFD2_k127_428080_49 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000008793 151.0
HFD2_k127_428080_5 Cytochrome bd-type quinol oxidase subunit 1 K00425 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 541.0
HFD2_k127_428080_50 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.000000000000000000000000000003742 125.0
HFD2_k127_428080_51 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000000000000000000003436 118.0
HFD2_k127_428080_52 histone H2A K63-linked ubiquitination - - - 0.0000000000000000000000006814 113.0
HFD2_k127_428080_53 Iodothyronine deiodinase - - - 0.0000000000000000000000007702 108.0
HFD2_k127_428080_54 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000002817 110.0
HFD2_k127_428080_55 regulation of translation K03530 - - 0.0000000000000000000001036 102.0
HFD2_k127_428080_56 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000000000000733 93.0
HFD2_k127_428080_58 General secretion pathway protein C K02452 - - 0.0000009465 58.0
HFD2_k127_428080_59 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589,K13052 - - 0.000003531 54.0
HFD2_k127_428080_6 Acyl-CoA dehydrogenase, C-terminal domain K16173 - 1.3.99.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 528.0
HFD2_k127_428080_60 Virulence factor BrkB K07058 - - 0.0001776 55.0
HFD2_k127_428080_7 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005308 469.0
HFD2_k127_428080_8 Cys/Met metabolism PLP-dependent enzyme K01739,K01758,K01760,K17217 - 2.5.1.48,4.4.1.1,4.4.1.2,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003683 457.0
HFD2_k127_428080_9 penicillin binding K05367 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007301 477.0
HFD2_k127_432759_0 PFAM amidohydrolase K01464 - 3.5.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 573.0
HFD2_k127_432759_1 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009533 492.0
HFD2_k127_432759_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K15372 - 2.6.1.19,2.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 500.0
HFD2_k127_432759_3 Dihydroorotate dehydrogenase K17723 GO:0003674,GO:0003824,GO:0003954,GO:0006139,GO:0006206,GO:0006208,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016491,GO:0016651,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 1.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003502 411.0
HFD2_k127_432759_4 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 347.0
HFD2_k127_432759_5 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002005 264.0
HFD2_k127_432759_6 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000001617 233.0
HFD2_k127_432759_7 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000005489 95.0
HFD2_k127_432759_8 - - - - 0.000000000000001465 78.0
HFD2_k127_432759_9 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.00000000001467 69.0
HFD2_k127_4355338_0 ABC1 family K03688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 602.0
HFD2_k127_4355338_1 COG0626 Cystathionine beta-lyases cystathionine gamma-synthases K01739,K01758 - 2.5.1.48,4.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 475.0
HFD2_k127_4355338_10 Homoserine dehydrogenase - - - 0.0000000000000000000000000000000000000000000000595 186.0
HFD2_k127_4355338_11 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 0.00000000000000000000000000000000001655 136.0
HFD2_k127_4355338_12 Putative zinc- or iron-chelating domain - - - 0.000000000000000000000000000000002469 148.0
HFD2_k127_4355338_13 PFAM Forkhead-associated protein - - - 0.000000000000003018 89.0
HFD2_k127_4355338_14 Glyoxalase-like domain - - - 0.000000000000007198 83.0
HFD2_k127_4355338_15 RDD family - - - 0.00000001221 67.0
HFD2_k127_4355338_2 Belongs to the CarA family K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 449.0
HFD2_k127_4355338_3 glycosyl transferase group 1 K00754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000848 423.0
HFD2_k127_4355338_4 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008993 391.0
HFD2_k127_4355338_5 Bacillithiol biosynthesis BshC K22136 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008772 287.0
HFD2_k127_4355338_6 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007194 267.0
HFD2_k127_4355338_8 GlcNAc-PI de-N-acetylase K01463 - - 0.000000000000000000000000000000000000000000000004529 181.0
HFD2_k127_4355338_9 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000003977 185.0
HFD2_k127_437845_0 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 342.0
HFD2_k127_437845_1 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000008685 193.0
HFD2_k127_4399712_0 secondary active sulfate transmembrane transporter activity K06901 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 506.0
HFD2_k127_4399712_1 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004962 363.0
HFD2_k127_4399712_2 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007175 255.0
HFD2_k127_4411274_0 Involved in the tonB-independent uptake of proteins - - - 5.53e-219 707.0
HFD2_k127_4411274_1 Sodium:solute symporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 364.0
HFD2_k127_4411274_2 - - - - 0.0002263 49.0
HFD2_k127_4414872_0 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009537 269.0
HFD2_k127_4414872_1 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000004906 180.0
HFD2_k127_4437161_0 4Fe-4S dicluster domain K00184 - - 0.0 1077.0
HFD2_k127_4437161_1 Polysulphide reductase, NrfD K00185 - - 1.011e-216 680.0
HFD2_k127_4437161_2 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003495 403.0
HFD2_k127_4437161_3 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 402.0
HFD2_k127_4437161_4 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008488 323.0
HFD2_k127_4437161_5 signal sequence binding K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007685 275.0
HFD2_k127_4437161_6 Protein of unknown function (DUF3341) - - - 0.000000000000000000000000000000000000000000000000000000000000000001688 243.0
HFD2_k127_4437161_7 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000003776 236.0
HFD2_k127_4437161_8 ECF sigma factor K03088 - - 0.0000000000000006517 86.0
HFD2_k127_4495703_0 PA14 K05349 - 3.2.1.21 2.852e-268 853.0
HFD2_k127_4495703_1 Glycosyl hydrolases family 15 - - - 3.783e-249 793.0
HFD2_k127_4495703_10 ABC-2 family transporter protein K01992 - - 0.00000000000000000003087 106.0
HFD2_k127_4495703_11 heat shock protein binding - - - 0.000000000000005605 88.0
HFD2_k127_4495703_12 Polymer-forming cytoskeletal - - - 0.000000000003836 74.0
HFD2_k127_4495703_2 Peptidase M16 inactive domain K07263 - - 1.296e-216 717.0
HFD2_k127_4495703_3 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005085 610.0
HFD2_k127_4495703_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000072 310.0
HFD2_k127_4495703_5 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 310.0
HFD2_k127_4495703_6 Sigma factor PP2C-like phosphatases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000143 273.0
HFD2_k127_4495703_7 Putative stress-induced transcription regulator - - - 0.00000000000000000000000000000000000000000003184 169.0
HFD2_k127_4495703_8 DinB superfamily - - - 0.00000000000000000000000000001108 123.0
HFD2_k127_4495703_9 - K01992,K19341 - - 0.000000000000000000000003521 114.0
HFD2_k127_4526986_0 Cytochrome c-type biogenesis protein K02198 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005609 321.0
HFD2_k127_4526986_1 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000000000000000435 144.0
HFD2_k127_4526986_2 Cytochrome C assembly protein K02195 - - 0.000000000000000000000000162 112.0
HFD2_k127_4531796_0 Response regulator receiver - - - 1.293e-201 636.0
HFD2_k127_4531796_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 452.0
HFD2_k127_4531796_2 PFAM ABC transporter K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 356.0
HFD2_k127_4531796_3 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004897 325.0
HFD2_k127_4531796_4 Transport permease protein K01992 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0015562,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0033554,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004267 330.0
HFD2_k127_4531796_5 transport, permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 325.0
HFD2_k127_4531796_6 ATPase activity K01990,K13926 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009237 299.0
HFD2_k127_4531796_7 MacB-like periplasmic core domain - - - 0.00000000000000000000000008047 109.0
HFD2_k127_4531796_8 Psort location OuterMembrane, score - - - 0.00000000000002533 87.0
HFD2_k127_4555121_0 ABC transporter, transmembrane K18889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004354 512.0
HFD2_k127_4555121_1 ABC transporter, transmembrane K18890 - - 0.000000000000000000000000000000000000000000000000000000000000002062 233.0
HFD2_k127_4564736_0 glycosyl transferase family K00697,K16055 - 2.4.1.15,2.4.1.347,3.1.3.12 4.285e-197 641.0
HFD2_k127_4564736_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 529.0
HFD2_k127_4564736_10 Belongs to the radical SAM superfamily. RlmN family K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000006697 267.0
HFD2_k127_4564736_11 chitin binding - - - 0.00000000000000000000000000000000000000000000018 187.0
HFD2_k127_4564736_12 manganese ion transmembrane transporter activity - - - 0.00000000000000000000000000000000000008268 164.0
HFD2_k127_4564736_13 Multi-copper polyphenol oxidoreductase laccase K05810 - - 0.0000000000000000000000000000000001159 143.0
HFD2_k127_4564736_14 Reverse transcriptase-like K03469 - 3.1.26.4 0.00000000000000000000000000000000158 143.0
HFD2_k127_4564736_15 C4-type zinc ribbon domain K07164 - - 0.00000000000000000000000000006011 132.0
HFD2_k127_4564736_16 Sigma factor PP2C-like phosphatases - - - 0.00000000000000000000000008967 119.0
HFD2_k127_4564736_18 Putative DNA-binding domain - - - 0.000000000000000000004777 107.0
HFD2_k127_4564736_19 - - - - 0.0000000000000002849 93.0
HFD2_k127_4564736_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 497.0
HFD2_k127_4564736_20 Essential cell division protein K03589 - - 0.00001977 57.0
HFD2_k127_4564736_22 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0002032 51.0
HFD2_k127_4564736_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007185 470.0
HFD2_k127_4564736_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007461 407.0
HFD2_k127_4564736_5 protein conserved in bacteria K09930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 383.0
HFD2_k127_4564736_6 metallophosphoesterase K07096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007081 311.0
HFD2_k127_4564736_7 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001656 289.0
HFD2_k127_4564736_8 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002533 298.0
HFD2_k127_4564736_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000278 292.0
HFD2_k127_4579673_0 cell redox homeostasis - - - 0.00000000000000000000000000004835 124.0
HFD2_k127_4579673_1 ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component K02004 - - 0.000000000000000001214 92.0
HFD2_k127_4579673_2 response regulator - - - 0.00008661 49.0
HFD2_k127_4583173_0 Cupin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006206 335.0
HFD2_k127_4583173_1 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004713 288.0
HFD2_k127_4583173_2 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.000000000000000000000000000000000000000000000000000000000000000003624 240.0
HFD2_k127_4605312_0 ligase activity, forming nitrogen-metal bonds K02230 - 6.6.1.2 0.0 1368.0
HFD2_k127_4605312_1 Amylo-alpha-1,6-glucosidase - - - 6.194e-236 772.0
HFD2_k127_4605312_2 AcrB/AcrD/AcrF family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 341.0
HFD2_k127_4605312_3 Putative zinc-finger K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 293.0
HFD2_k127_4605312_4 PFAM Mannosyl oligosaccharide glucosidase - - - 0.0000000000000000000000000000000000001366 146.0
HFD2_k127_4605312_5 Protein of unknown function (DUF2892) - - - 0.0000000000000000007769 90.0
HFD2_k127_4605312_6 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000008661 71.0
HFD2_k127_4613923_0 Involved in the tonB-independent uptake of proteins - - - 2.458e-210 685.0
HFD2_k127_4613923_1 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 466.0
HFD2_k127_4613923_2 Peptidase family M28 K05994 - 3.4.11.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009507 386.0
HFD2_k127_4613923_3 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000253 202.0
HFD2_k127_4613923_4 Nuclear protein SET K07117 - - 0.0000000000002912 76.0
HFD2_k127_4613923_5 Vacuole effluxer Atg22 like K06902 - - 0.0000000002108 62.0
HFD2_k127_4613923_6 Protein of unknown function (DUF3187) - - - 0.000000007602 67.0
HFD2_k127_4627384_0 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.0 1720.0
HFD2_k127_4627384_1 PFAM glycosyl hydrolase BNR repeat-containing protein - - - 0.0 1144.0
HFD2_k127_4627384_10 Dodecin K09165 - - 0.000000000000000001001 96.0
HFD2_k127_4627384_11 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00003188 47.0
HFD2_k127_4627384_12 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.0001119 52.0
HFD2_k127_4627384_2 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679,K01744 - 4.2.1.2,4.3.1.1 2.461e-224 702.0
HFD2_k127_4627384_3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00615,K00616 - 2.2.1.1,2.2.1.2 6.462e-221 701.0
HFD2_k127_4627384_4 Y_Y_Y domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 528.0
HFD2_k127_4627384_5 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000006331 220.0
HFD2_k127_4627384_6 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000000000000000000224 188.0
HFD2_k127_4627384_7 translation initiation inhibitor, yjgF family K04782 - 4.2.99.21 0.00000000000000000000000000000000000000000000000003875 183.0
HFD2_k127_4627384_8 BMC K04025 - - 0.00000000000000000000000000000000004765 140.0
HFD2_k127_4627384_9 4Fe-4S dicluster domain K05524 - - 0.00000000000000000000000000000001983 138.0
HFD2_k127_4656357_0 AMP-binding enzyme C-terminal domain K08295 - 6.2.1.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 506.0
HFD2_k127_4656357_1 Male sterility protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 402.0
HFD2_k127_4656357_10 domain protein K20276 - - 0.00000000000000000000000000000000000000000000000000005913 206.0
HFD2_k127_4656357_11 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000008649 194.0
HFD2_k127_4656357_12 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000006261 190.0
HFD2_k127_4656357_13 Metallo-peptidase family M12 - - - 0.000000000000000000000000000001144 138.0
HFD2_k127_4656357_14 thiolester hydrolase activity - - - 0.0000000000000000000000002763 119.0
HFD2_k127_4656357_15 Domain of unknown function (DUF4349) - - - 0.000000000000000000000002151 114.0
HFD2_k127_4656357_16 Thioesterase superfamily K01075 - 3.1.2.23 0.0000000000000000001037 97.0
HFD2_k127_4656357_17 peroxiredoxin activity K01607 - 4.1.1.44 0.00000000000003556 78.0
HFD2_k127_4656357_18 glycolate biosynthetic process K01091,K06019,K13292 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.1.3.18,3.6.1.1 0.0000000000004035 77.0
HFD2_k127_4656357_19 - - - - 0.00000009579 63.0
HFD2_k127_4656357_2 GHMP kinases C terminal K07031 - 2.7.1.168 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003605 385.0
HFD2_k127_4656357_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 320.0
HFD2_k127_4656357_4 Histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 308.0
HFD2_k127_4656357_5 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004113 298.0
HFD2_k127_4656357_6 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004133 286.0
HFD2_k127_4656357_7 PFAM thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000129 253.0
HFD2_k127_4656357_8 D-glycero-D-manno-heptose 7-phosphate metabolic process K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000001537 263.0
HFD2_k127_4656357_9 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00966 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000001154 229.0
HFD2_k127_4663081_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 378.0
HFD2_k127_4663081_1 FecR protein - - - 0.0000000007877 70.0
HFD2_k127_4714159_0 Ppx/GppA phosphatase family - - - 0.000000000000000000000000000000000000001481 151.0
HFD2_k127_4714159_1 COGs COG1392 Phosphate transport regulator (distant homolog of PhoU) K07220 - - 0.0000000000000000000000000000000000000175 153.0
HFD2_k127_4714159_2 Lysylphosphatidylglycerol synthase TM region - - - 0.00000000000000000000000000000002833 139.0
HFD2_k127_4714923_0 family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 451.0
HFD2_k127_4714923_1 Copper/zinc superoxide dismutase (SODC) K04565 - 1.15.1.1 0.00000000000000000000000000001985 127.0
HFD2_k127_4714923_2 Bacterial membrane protein YfhO - - - 0.00000000000000000000000002753 128.0
HFD2_k127_4714923_3 oligosaccharyl transferase activity - - - 0.0000000000000000747 93.0
HFD2_k127_4716925_0 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007948 315.0
HFD2_k127_4716925_1 PFAM Patatin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001701 282.0
HFD2_k127_4718969_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 497.0
HFD2_k127_4718969_1 NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 483.0
HFD2_k127_4718969_2 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 353.0
HFD2_k127_4718969_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 368.0
HFD2_k127_4718969_4 Belongs to the pyruvate kinase family K00873 GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 0.00000000000000000000000000000000000000000005538 170.0
HFD2_k127_4718969_5 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K00330 - 1.6.5.3 0.000000000000000000000000000000000001418 142.0
HFD2_k127_4718969_6 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000008058 127.0
HFD2_k127_4718969_7 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000000005695 115.0
HFD2_k127_4718969_8 plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000004762 98.0
HFD2_k127_4742805_0 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 0.0 1241.0
HFD2_k127_4742805_1 Prolyl oligopeptidase family - - - 3.514e-218 705.0
HFD2_k127_4742805_10 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 346.0
HFD2_k127_4742805_11 Inward rectifier potassium channel K08715 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 291.0
HFD2_k127_4742805_12 ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001065 279.0
HFD2_k127_4742805_13 Protein of unknown function (DUF1211) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007271 273.0
HFD2_k127_4742805_14 Belongs to the Glu Leu Phe Val dehydrogenases family K00263 - 1.4.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000001434 284.0
HFD2_k127_4742805_15 Binding-protein-dependent transport system inner membrane component K11071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004351 275.0
HFD2_k127_4742805_16 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003813 271.0
HFD2_k127_4742805_17 PFAM alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000002729 212.0
HFD2_k127_4742805_18 DinB superfamily - - - 0.00000000000000000000000000000000000000000006024 166.0
HFD2_k127_4742805_19 PFAM phospholipase Carboxylesterase - - - 0.000000000000000000000000000000000000000002921 163.0
HFD2_k127_4742805_2 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 501.0
HFD2_k127_4742805_20 Protein of unknown function (DUF962) - - - 0.00000000000000000000000000005651 136.0
HFD2_k127_4742805_21 Outer membrane lipoprotein-sorting protein - - - 0.0000000000000000000000000008406 123.0
HFD2_k127_4742805_22 - - - - 0.000000000000000000000000003155 124.0
HFD2_k127_4742805_23 Thioesterase superfamily - - - 0.00000000000000000000000005383 121.0
HFD2_k127_4742805_24 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.00000000000000000000748 105.0
HFD2_k127_4742805_25 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000002919 84.0
HFD2_k127_4742805_26 Protein involved in meta-pathway of phenol degradation - - - 0.0000000000003817 80.0
HFD2_k127_4742805_28 - - - - 0.000000000001126 80.0
HFD2_k127_4742805_3 POT family K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 494.0
HFD2_k127_4742805_30 Domain of unknown function (DUF4437) - - - 0.0000001875 64.0
HFD2_k127_4742805_4 ABC transporter, solute-binding protein K11069,K11070 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 448.0
HFD2_k127_4742805_5 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006532 428.0
HFD2_k127_4742805_6 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 378.0
HFD2_k127_4742805_7 NAD dependent epimerase/dehydratase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 374.0
HFD2_k127_4742805_8 Sugar (and other) transporter K08178 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 359.0
HFD2_k127_4742805_9 Zinc-binding dehydrogenase K00055,K00121 - 1.1.1.1,1.1.1.284,1.1.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 353.0
HFD2_k127_4762082_0 MacB-like periplasmic core domain - - - 4.624e-286 903.0
HFD2_k127_4762082_1 FecR protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 497.0
HFD2_k127_4762082_10 Protein of unknown function (DUF1579) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003642 252.0
HFD2_k127_4762082_11 Lipase (class 3) - - - 0.00000000000000000000000000000000000000000000000000000000000000673 225.0
HFD2_k127_4762082_12 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.00000000000000000000000000000000000000000000000000000000000003458 235.0
HFD2_k127_4762082_13 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000006974 206.0
HFD2_k127_4762082_14 - - - - 0.00000000000000000000000000000000000000000000000000000107 216.0
HFD2_k127_4762082_15 Amidase K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000001131 198.0
HFD2_k127_4762082_16 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000001762 145.0
HFD2_k127_4762082_17 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0000000000000000004862 98.0
HFD2_k127_4762082_18 Trypsin K04771 - 3.4.21.107 0.00000006927 63.0
HFD2_k127_4762082_2 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004926 466.0
HFD2_k127_4762082_3 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 445.0
HFD2_k127_4762082_4 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007934 452.0
HFD2_k127_4762082_5 Bacterial protein of unknown function (DUF899) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003623 419.0
HFD2_k127_4762082_6 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009386 418.0
HFD2_k127_4762082_7 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007151 392.0
HFD2_k127_4762082_8 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 353.0
HFD2_k127_4762082_9 DJ-1/PfpI family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001189 253.0
HFD2_k127_4765272_0 PFAM CheW domain protein K03408 - - 0.00000000000000000000000000000000000000005253 162.0
HFD2_k127_4765272_1 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.00000000000000000000000000000000000000009344 156.0
HFD2_k127_4776959_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1496.0
HFD2_k127_4776959_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 361.0
HFD2_k127_4776959_2 Secretion protein K01993 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0071944 - 0.0000000000000000000000000000000000000000000001543 193.0
HFD2_k127_4776959_3 transcriptional regulator - - - 0.0000000000000000000009651 103.0
HFD2_k127_4788363_0 amino acid - - - 1.889e-233 739.0
HFD2_k127_4788363_1 Enoyl-CoA hydratase/isomerase K15513 - 4.1.2.44 4.025e-231 726.0
HFD2_k127_4788363_10 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K15546 - - 0.0000000000000000000000000000000000000000000000000000000000001321 222.0
HFD2_k127_4788363_11 NAD+ binding - - - 0.0000000000000000000000000000000000000000000000000000164 209.0
HFD2_k127_4788363_12 - K07018 - - 0.000000000000000000000000000000000000000000000000001707 190.0
HFD2_k127_4788363_13 OsmC-like protein K06889,K07397 - - 0.000000000000000000000000000000000000000000000000001778 186.0
HFD2_k127_4788363_14 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000006264 188.0
HFD2_k127_4788363_15 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000006693 184.0
HFD2_k127_4788363_16 - - - - 0.0000000000000000000000000000000000001016 163.0
HFD2_k127_4788363_17 Gram-negative-bacterium-type cell wall biogenesis - - - 0.000000000000000000000000000000000355 139.0
HFD2_k127_4788363_18 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000005095 143.0
HFD2_k127_4788363_19 PFAM PRC-barrel domain - - - 0.000000000000000000000000000000027 129.0
HFD2_k127_4788363_2 benzoyl-CoA oxygenase K15512 - 1.14.13.208 3.78e-222 696.0
HFD2_k127_4788363_20 Transcriptional regulator K03892 - - 0.000000000000000000000000000002501 124.0
HFD2_k127_4788363_21 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000002563 109.0
HFD2_k127_4788363_22 Transmembrane secretion effector - - - 0.0000000000000000002844 101.0
HFD2_k127_4788363_25 Belongs to the peptidase S8 family - - - 0.0000000000000006251 92.0
HFD2_k127_4788363_26 - - - - 0.00000000000001955 87.0
HFD2_k127_4788363_27 Membrane - - - 0.0000000000001653 84.0
HFD2_k127_4788363_29 Domain of unknown function (DUF1851) - - - 0.000003709 57.0
HFD2_k127_4788363_3 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 1.844e-212 672.0
HFD2_k127_4788363_30 Acetyltransferase (GNAT) domain - - - 0.0003874 48.0
HFD2_k127_4788363_4 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009083 495.0
HFD2_k127_4788363_5 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 490.0
HFD2_k127_4788363_6 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005075 447.0
HFD2_k127_4788363_7 PFAM natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 446.0
HFD2_k127_4788363_8 Aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001104 310.0
HFD2_k127_4788363_9 Methyltransferase type 11 K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000001012 247.0
HFD2_k127_4815952_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.767e-232 734.0
HFD2_k127_4815952_1 General secretory system II, protein E domain protein K02454 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 464.0
HFD2_k127_4815952_2 Arginase family K01476 - 3.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007717 358.0
HFD2_k127_4815952_3 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 344.0
HFD2_k127_4815952_4 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 329.0
HFD2_k127_4815952_5 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000501 291.0
HFD2_k127_4815952_6 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000005478 203.0
HFD2_k127_4815952_7 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000000004083 152.0
HFD2_k127_4815952_8 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000001678 63.0
HFD2_k127_4815952_9 COG3678 P pilus assembly Cpx signaling pathway, periplasmic inhibitor zinc-resistance associated protein K06006 - - 0.000006218 55.0
HFD2_k127_4859831_0 Cytochrome c554 and c-prime - - - 2.801e-308 972.0
HFD2_k127_4859831_1 TonB-dependent Receptor Plug Domain - - - 1.835e-241 786.0
HFD2_k127_4859831_2 ASPIC and UnbV - - - 2.037e-194 661.0
HFD2_k127_4859831_3 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 530.0
HFD2_k127_4859831_4 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 464.0
HFD2_k127_4859831_5 SIS domain K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 339.0
HFD2_k127_4859831_6 cyclopropane-fatty-acyl-phospholipid synthase K00574,K07154,K14369,K15257,K18534 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0016999,GO:0017000,GO:0017144,GO:0032259,GO:0044237,GO:0044249 2.1.1.254,2.1.1.295,2.1.1.79,2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 316.0
HFD2_k127_4859831_7 BadF/BadG/BcrA/BcrD ATPase family K00884 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006040,GO:0006044,GO:0006082,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0045127,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901071,GO:1901135,GO:1901265,GO:1901363 2.7.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002914 297.0
HFD2_k127_4859831_8 arylsulfatase A - - - 0.000000000000000000000000000000000000000000000000000000000000000000009265 246.0
HFD2_k127_4859831_9 COG0526, thiol-disulfide isomerase and thioredoxins K03671 - - 0.00000000000000000007025 90.0
HFD2_k127_4867385_0 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 597.0
HFD2_k127_4867385_1 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003729 366.0
HFD2_k127_4867385_2 PFAM Hemolysin-type calcium-binding K01406 - 3.4.24.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009973 309.0
HFD2_k127_4867385_3 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 303.0
HFD2_k127_4867385_4 radical SAM domain protein K22227 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002404 281.0
HFD2_k127_4867385_5 PFAM Hemolysin-type calcium-binding K01406 - 3.4.24.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004862 279.0
HFD2_k127_4867385_6 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000004903 289.0
HFD2_k127_4867385_7 Nicotinamide mononucleotide transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000006715 226.0
HFD2_k127_4867385_8 - - - - 0.000000000000000000000000000000000000000000000000000007722 208.0
HFD2_k127_4867385_9 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000002775 76.0
HFD2_k127_4916438_0 ABC transporter K15738 - - 2.172e-236 742.0
HFD2_k127_4916438_1 TonB-dependent Receptor Plug Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005672 393.0
HFD2_k127_4916438_2 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 335.0
HFD2_k127_4916438_3 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000001325 154.0
HFD2_k127_4916438_4 Amino-transferase class IV K00826 - 2.6.1.42 0.0000000000000000000000001201 117.0
HFD2_k127_4916438_5 3-beta hydroxysteroid dehydrogenase isomerase - - - 0.00000000000000000001637 104.0
HFD2_k127_4916438_6 Sigma-70 region 2 K03088 - - 0.0000000000001919 81.0
HFD2_k127_4918793_0 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004148 311.0
HFD2_k127_4918793_1 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.000000001865 59.0
HFD2_k127_4918793_2 - - - - 0.0000003013 54.0
HFD2_k127_4918793_3 Methyltransferase domain - - - 0.000004787 59.0
HFD2_k127_4932765_0 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004344 349.0
HFD2_k127_4932765_1 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000003139 143.0
HFD2_k127_4999587_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 527.0
HFD2_k127_4999587_1 Fatty acid hydroxylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 441.0
HFD2_k127_4999587_10 Bacterial membrane protein YfhO - - - 0.00000001331 68.0
HFD2_k127_4999587_11 von Willebrand factor, type A - - - 0.0009559 51.0
HFD2_k127_4999587_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 310.0
HFD2_k127_4999587_3 PFAM MscS Mechanosensitive ion channel K16052 - - 0.000000000000000000000000000000000000000000000000000003475 216.0
HFD2_k127_4999587_4 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.0000000000000000000000000000000000000000000000000007801 196.0
HFD2_k127_4999587_5 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K02014 - - 0.000000000000000000000000000000000000000000000000003126 207.0
HFD2_k127_4999587_6 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.00000000000000000000000000000002792 146.0
HFD2_k127_4999587_7 Histidine kinase - - - 0.00000000000000000000000000002207 133.0
HFD2_k127_4999587_8 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000004778 96.0
HFD2_k127_4999587_9 Autotransporter beta-domain - - - 0.0000000002249 74.0
HFD2_k127_5011783_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 1.562e-312 990.0
HFD2_k127_5011783_1 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006499 378.0
HFD2_k127_5011783_10 PAP2 superfamily - - - 0.000000000000002865 86.0
HFD2_k127_5011783_2 ornithine cyclodeaminase activity K01750,K18258,K19244 - 1.4.1.1,1.5.1.25,4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007701 323.0
HFD2_k127_5011783_3 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006695 265.0
HFD2_k127_5011783_4 AcrB/AcrD/AcrF family K03296 - - 0.0000000000000000000000000000000000000000001389 177.0
HFD2_k127_5011783_5 Transcriptional regulator - - - 0.0000000000000000000000000000000000003032 158.0
HFD2_k127_5011783_6 ABC-type sugar transport system periplasmic component K10439 - - 0.000000000000000000000000000000000916 151.0
HFD2_k127_5011783_7 glyoxalase III activity - - - 0.000000000000000000000000000001577 126.0
HFD2_k127_5011783_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000002924 139.0
HFD2_k127_5011783_9 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000002808 119.0
HFD2_k127_5247742_0 TonB-dependent Receptor Plug Domain - - - 2.217e-284 910.0
HFD2_k127_5247742_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003563 541.0
HFD2_k127_5247742_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004982 467.0
HFD2_k127_5247742_3 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003458 399.0
HFD2_k127_5247742_4 Biotin-lipoyl like K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 409.0
HFD2_k127_5247742_5 Carbohydrate ABC transporter ATP-binding protein, CUT1 family K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 355.0
HFD2_k127_5247742_6 ATPases associated with a variety of cellular activities K10441 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001533 289.0
HFD2_k127_5247742_7 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000000000000000002092 182.0
HFD2_k127_5247742_8 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0000000000000000000000000007715 132.0
HFD2_k127_5261557_0 ATP-dependent DNA helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 313.0
HFD2_k127_5261557_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001078 277.0
HFD2_k127_5288716_0 DNA-templated transcription, termination K02887,K03628 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 381.0
HFD2_k127_5288716_1 protein).. Source PGD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001666 269.0
HFD2_k127_5288716_2 Putative esterase - - - 0.000000000000000000000794 99.0
HFD2_k127_5317717_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004473 564.0
HFD2_k127_5317717_1 COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K03520,K11177 - 1.17.1.4,1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 445.0
HFD2_k127_5317717_2 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000601 368.0
HFD2_k127_5327433_0 Aldehyde dehydrogenase family K00294 - 1.2.1.88 1.332e-243 767.0
HFD2_k127_5327433_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 620.0
HFD2_k127_5327433_10 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 323.0
HFD2_k127_5327433_11 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 315.0
HFD2_k127_5327433_12 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000447 286.0
HFD2_k127_5327433_13 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin K13274,K14645 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006537 283.0
HFD2_k127_5327433_14 modulates the activities of several proteins which are inactive in their K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001494 271.0
HFD2_k127_5327433_15 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002566 270.0
HFD2_k127_5327433_16 NADPH-dependent F420 reductase K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000000000001574 231.0
HFD2_k127_5327433_17 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000001243 209.0
HFD2_k127_5327433_18 response regulator - - - 0.000000000000000000000000000000000000000000000000000000007147 207.0
HFD2_k127_5327433_19 - - - - 0.000000000000000000000000000000000000000000000000000002186 199.0
HFD2_k127_5327433_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003732 605.0
HFD2_k127_5327433_20 - - - - 0.000000000000000000000000000000000000000000000000000003031 207.0
HFD2_k127_5327433_21 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000000000001274 200.0
HFD2_k127_5327433_22 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000001621 199.0
HFD2_k127_5327433_23 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000000001068 205.0
HFD2_k127_5327433_24 DinB family - - - 0.0000000000000000000000000000000000000000000000001747 185.0
HFD2_k127_5327433_25 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000000008899 171.0
HFD2_k127_5327433_26 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000005752 179.0
HFD2_k127_5327433_27 PFAM CBS domain containing protein K06189 - - 0.00000000000000000000000000000000000000000009054 177.0
HFD2_k127_5327433_28 Trehalose utilisation - - - 0.0000000000000000000000000000000002991 147.0
HFD2_k127_5327433_29 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000002989 121.0
HFD2_k127_5327433_3 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006543 563.0
HFD2_k127_5327433_30 - - - - 0.0000000000000000000000000001784 119.0
HFD2_k127_5327433_31 transcriptional regulator - - - 0.0000000000000000000000000001842 128.0
HFD2_k127_5327433_32 SnoaL-like domain - - - 0.0000000000000000000000000002815 120.0
HFD2_k127_5327433_33 serine-type peptidase activity - - - 0.0000000000000000000002212 111.0
HFD2_k127_5327433_34 - - - - 0.000000000000000000005701 93.0
HFD2_k127_5327433_35 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.00000000000000006591 93.0
HFD2_k127_5327433_36 sodium ABC transporter, permease K09696 - - 0.000000000002599 81.0
HFD2_k127_5327433_37 exo-alpha-(2->6)-sialidase activity - - - 0.000002648 61.0
HFD2_k127_5327433_39 cell adhesion involved in biofilm formation - - - 0.00001111 56.0
HFD2_k127_5327433_4 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005659 538.0
HFD2_k127_5327433_41 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0003338 52.0
HFD2_k127_5327433_42 phosphorelay signal transduction system - - - 0.0003543 54.0
HFD2_k127_5327433_5 PFAM tRNA synthetase, class II (G, H, P and S) K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004926 422.0
HFD2_k127_5327433_6 GTP binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 417.0
HFD2_k127_5327433_7 GGDEF domain K13243 - 3.1.4.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 416.0
HFD2_k127_5327433_8 PFAM PhoH family protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000766 373.0
HFD2_k127_5327433_9 Belongs to the LarC family K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 346.0
HFD2_k127_5331281_0 Belongs to the peptidase M16 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 449.0
HFD2_k127_5331281_1 oxidation-reduction process K09022 - 3.5.99.10 0.00000000000000000000000000000000000000000000000008951 180.0
HFD2_k127_5331281_2 Predicted membrane protein (DUF2079) - - - 0.0000000000000000000006269 113.0
HFD2_k127_5331281_3 - - - - 0.0000000002407 74.0
HFD2_k127_53348_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003041 374.0
HFD2_k127_53348_1 protein).. Source PGD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002876 271.0
HFD2_k127_53348_2 FCD K05799 - - 0.00000000000000000000000000000000000000000000000000000000000000002379 233.0
HFD2_k127_53348_3 - - - - 0.0000000000000000000000000000000000003288 158.0
HFD2_k127_53348_4 KR domain - - - 0.0000001641 62.0
HFD2_k127_5337306_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 3.881e-265 839.0
HFD2_k127_5337306_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 1.388e-263 835.0
HFD2_k127_5337306_10 AIR synthase related protein, N-terminal domain K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 319.0
HFD2_k127_5337306_11 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 304.0
HFD2_k127_5337306_12 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000199 285.0
HFD2_k127_5337306_13 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001693 271.0
HFD2_k127_5337306_14 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000004639 232.0
HFD2_k127_5337306_15 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000000001194 117.0
HFD2_k127_5337306_16 Polymer-forming cytoskeletal - - - 0.0000000000000000000004104 102.0
HFD2_k127_5337306_17 rRNA methyltransferase activity K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.000000000000000002991 96.0
HFD2_k127_5337306_18 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000004314 86.0
HFD2_k127_5337306_19 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000005639 85.0
HFD2_k127_5337306_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 1.088e-240 758.0
HFD2_k127_5337306_20 R3H domain protein K06346 - - 0.00000000000004168 87.0
HFD2_k127_5337306_21 Ribosomal protein L34 K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000006156 70.0
HFD2_k127_5337306_22 Tetratricopeptide repeat - - - 0.0001671 51.0
HFD2_k127_5337306_3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 3.752e-236 754.0
HFD2_k127_5337306_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 3.006e-225 707.0
HFD2_k127_5337306_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.895e-224 720.0
HFD2_k127_5337306_6 ATP-dependent DNA helicase activity K03656,K03657 GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002847 605.0
HFD2_k127_5337306_7 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 496.0
HFD2_k127_5337306_8 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006375 432.0
HFD2_k127_5337306_9 NUBPL iron-transfer P-loop NTPase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 323.0
HFD2_k127_534556_0 Belongs to the glycosyl hydrolase 2 family K01190 - 3.2.1.23 0.0 1107.0
HFD2_k127_534556_1 snf2 family K08282 - 2.7.11.1 1.015e-312 990.0
HFD2_k127_534556_10 Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005004 410.0
HFD2_k127_534556_11 COG2706 3-carboxymuconate cyclase K07404 - 3.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004262 374.0
HFD2_k127_534556_12 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007946 380.0
HFD2_k127_534556_13 protein kinase activity K01972,K02342,K04096 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 2.7.7.7,6.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005938 357.0
HFD2_k127_534556_14 SWIM zinc finger - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007919 265.0
HFD2_k127_534556_15 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000002986 235.0
HFD2_k127_534556_16 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000007535 222.0
HFD2_k127_534556_17 membrane - - - 0.0000000000000000000000000000000000000000000000000000003635 210.0
HFD2_k127_534556_18 ABC-type sugar transport system periplasmic component K02058,K10439 - - 0.0000000000000000000000000000000000000000000000008253 186.0
HFD2_k127_534556_19 Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000004874 172.0
HFD2_k127_534556_2 Belongs to the glycosyl hydrolase 67 family K01235 - 3.2.1.139 1.609e-263 829.0
HFD2_k127_534556_20 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.0000000000000000000000000000000002997 133.0
HFD2_k127_534556_21 - - - - 0.0000000000000000000000005655 123.0
HFD2_k127_534556_22 beta-lactamase activity K07126 - - 0.000000000000000000000001828 121.0
HFD2_k127_534556_23 - - - - 0.000000000000000000000005982 111.0
HFD2_k127_534556_24 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.00000000000000000003847 102.0
HFD2_k127_534556_25 protein conserved in bacteria - - - 0.00000000000000000006164 98.0
HFD2_k127_534556_27 beta-lactamase activity K07126 - - 0.000000000000752 83.0
HFD2_k127_534556_28 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000008209 69.0
HFD2_k127_534556_29 Collagen triple helix repeat (20 copies) - - - 0.0000005488 59.0
HFD2_k127_534556_3 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 1.294e-249 783.0
HFD2_k127_534556_31 beta-lactamase activity K07126 GO:0003674,GO:0003824,GO:0008800,GO:0016787,GO:0016810,GO:0016812 - 0.0005886 54.0
HFD2_k127_534556_4 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 3.855e-236 745.0
HFD2_k127_534556_5 Alpha-L-fucosidase C-terminal domain - - - 4.845e-206 653.0
HFD2_k127_534556_6 ABC transporter K10441 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 602.0
HFD2_k127_534556_7 Melibiase K07407 - 3.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 503.0
HFD2_k127_534556_8 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005744 441.0
HFD2_k127_534556_9 ABC-type sugar transport system periplasmic component K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004271 429.0
HFD2_k127_5352098_0 Molydopterin dinucleotide binding domain K08352 - 1.8.5.5 5.814e-275 861.0
HFD2_k127_5352098_1 Peptidase family M49 - - - 7.075e-231 733.0
HFD2_k127_5352098_10 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000001257 87.0
HFD2_k127_5352098_11 - - - - 0.000000000002724 74.0
HFD2_k127_5352098_2 membrane protein, terc K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009956 400.0
HFD2_k127_5352098_3 Metallopeptidase family M24 K01262,K01271 - 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004954 332.0
HFD2_k127_5352098_4 serine-type peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002527 280.0
HFD2_k127_5352098_5 Redoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000002586 248.0
HFD2_k127_5352098_6 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000622 242.0
HFD2_k127_5352098_7 Disulphide bond corrector protein DsbC K04084 - 1.8.1.8 0.00000000000000000000000000000000000000009802 164.0
HFD2_k127_5352098_8 helix_turn_helix gluconate operon transcriptional repressor K07978 - - 0.00000000000000000000000000000001165 138.0
HFD2_k127_5352098_9 alpha beta K06889 - - 0.0000000000000000000005547 110.0
HFD2_k127_5353479_0 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007226 503.0
HFD2_k127_5353479_1 Cytochrome c - - - 0.00000000000000000000000000000001803 143.0
HFD2_k127_5353479_2 Cytochrome c - - - 0.000000000000000000003771 105.0
HFD2_k127_5389561_0 Isocitrate lyase K01637 GO:0003674,GO:0003824,GO:0004451,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0006102,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046421,GO:0046487,GO:0071704,GO:0072350 4.1.3.1 0.0 1069.0
HFD2_k127_5389561_1 Belongs to the malate synthase family K01638 - 2.3.3.9 6.725e-305 946.0
HFD2_k127_5389561_2 (ABC) transporter K15738 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005405 586.0
HFD2_k127_5389561_3 Belongs to the glycosyl hydrolase 43 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 589.0
HFD2_k127_5389561_4 Belongs to the glycosyl hydrolase 28 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000507 573.0
HFD2_k127_5389561_5 cAMP biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000808 522.0
HFD2_k127_5389561_6 lactate racemase activity K22373 - 5.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008895 496.0
HFD2_k127_5389561_7 PFAM Excinuclease ABC C subunit domain protein K07461 - - 0.000000000000000000001663 96.0
HFD2_k127_5391476_0 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00207,K12527,K17723 - 1.3.1.1,1.3.1.2,1.97.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 623.0
HFD2_k127_5391476_1 Amidohydrolase family K01465,K06015 - 3.5.1.81,3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006285 557.0
HFD2_k127_5391476_2 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006832 505.0
HFD2_k127_5391476_3 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 438.0
HFD2_k127_5391476_4 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 427.0
HFD2_k127_5391476_5 Threonine dehydratase K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004435 451.0
HFD2_k127_5391476_6 ATP dependent DNA ligase domain protein K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 361.0
HFD2_k127_5391476_7 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000632 363.0
HFD2_k127_5468683_0 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007362 340.0
HFD2_k127_5468683_1 translation release factor activity K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.00000000000000000000000000001659 124.0
HFD2_k127_5468683_2 SdiA-regulated - - - 0.00000000000002171 86.0
HFD2_k127_5505001_0 Protein involved in catalytic activity, cation binding and carbohydrate metabolic process K05343 - 3.2.1.1,5.4.99.16 4.216e-230 724.0
HFD2_k127_5505001_1 peptidase - - - 3.315e-227 733.0
HFD2_k127_5505001_10 peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004865 489.0
HFD2_k127_5505001_11 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 357.0
HFD2_k127_5505001_12 oxidoreductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002726 355.0
HFD2_k127_5505001_13 PHP domain protein K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009414 311.0
HFD2_k127_5505001_14 Belongs to the arylamine N-acetyltransferase family K00675 - 2.3.1.118 0.000000000000000000000000000000000000000000000000000000000000000000000000000714 262.0
HFD2_k127_5505001_15 competence protein COMEC - - - 0.0000000000000000000000000000000000000000000000000000000000000000006422 244.0
HFD2_k127_5505001_16 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000001523 254.0
HFD2_k127_5505001_17 COG0363 6-phosphogluconolactonase Glucosamine-6-phosphate isomerase deaminase K02080,K02564 - 3.5.99.6 0.00000000000000000000000000000000000000000000000000000000000000007417 231.0
HFD2_k127_5505001_18 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000002734 169.0
HFD2_k127_5505001_19 COGs COG2380 conserved - - - 0.000000000000000000000000000000000000003406 169.0
HFD2_k127_5505001_2 radical SAM domain protein - - - 1.378e-212 671.0
HFD2_k127_5505001_20 RNA polymerase sigma factor K03088 - - 0.000000000000000000000000000000004854 138.0
HFD2_k127_5505001_21 Putative zinc-finger - - - 0.000000000000000000000000000001536 137.0
HFD2_k127_5505001_22 PFAM Cold-shock protein, DNA-binding K03704 - - 0.0000000000000000000000001509 107.0
HFD2_k127_5505001_23 PFAM RNA recognition motif - - - 0.0000000000000000000000009873 109.0
HFD2_k127_5505001_24 Putative phosphatase (DUF442) - - - 0.000000000000001899 89.0
HFD2_k127_5505001_25 Tetratricopeptide repeat - - - 0.00000000000002434 85.0
HFD2_k127_5505001_26 ATPase activity K01990,K09695 - - 0.00000000005548 76.0
HFD2_k127_5505001_27 Protein tyrosine kinase - - - 0.0006004 52.0
HFD2_k127_5505001_3 Flavin-binding monooxygenase-like - - - 2.334e-209 668.0
HFD2_k127_5505001_4 COG0433 Predicted ATPase K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004129 607.0
HFD2_k127_5505001_5 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008667 606.0
HFD2_k127_5505001_6 electron transfer activity K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 586.0
HFD2_k127_5505001_7 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 580.0
HFD2_k127_5505001_8 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 558.0
HFD2_k127_5505001_9 FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 533.0
HFD2_k127_5522854_0 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 300.0
HFD2_k127_5522854_1 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000002802 232.0
HFD2_k127_5522854_2 GARP complex subunit (Sac2) K20298 GO:0000149,GO:0000938,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0005829,GO:0006810,GO:0006886,GO:0006892,GO:0006896,GO:0007034,GO:0008104,GO:0008150,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010506,GO:0010508,GO:0012505,GO:0015031,GO:0015833,GO:0016192,GO:0016197,GO:0016239,GO:0016241,GO:0016482,GO:0017016,GO:0017137,GO:0019222,GO:0019725,GO:0019899,GO:0019905,GO:0030029,GO:0031267,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0031410,GO:0031982,GO:0032456,GO:0032991,GO:0033036,GO:0034613,GO:0042147,GO:0042592,GO:0042886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044431,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046907,GO:0048193,GO:0048518,GO:0048522,GO:0048878,GO:0050789,GO:0050794,GO:0051020,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055082,GO:0055088,GO:0065007,GO:0065008,GO:0070727,GO:0071702,GO:0071705,GO:0090156,GO:0097708,GO:0099023 - 0.0000000000000000000000000001218 116.0
HFD2_k127_5549328_0 Tetratricopeptide repeat - - - 1.386e-197 649.0
HFD2_k127_5549328_1 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003918 431.0
HFD2_k127_5549328_10 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000001724 198.0
HFD2_k127_5549328_11 Serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.00000000000000000000000000000000000000000001178 183.0
HFD2_k127_5549328_12 TIR domain - - - 0.0000000000000000000007868 111.0
HFD2_k127_5549328_13 Caspase domain - - - 0.0000000000000000000051 109.0
HFD2_k127_5549328_14 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit K07315 - 3.1.3.3 0.0000000001593 74.0
HFD2_k127_5549328_15 Serine threonine-protein phosphatase K04460 GO:0003674,GO:0003824,GO:0004721,GO:0004722,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005654,GO:0005737,GO:0005783,GO:0005789,GO:0005829,GO:0005911,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006913,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009314,GO:0009416,GO:0009506,GO:0009628,GO:0009639,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010017,GO:0010019,GO:0010035,GO:0010038,GO:0010380,GO:0012505,GO:0016020,GO:0016021,GO:0016311,GO:0016604,GO:0016607,GO:0016787,GO:0016788,GO:0016791,GO:0019222,GO:0019538,GO:0023052,GO:0030054,GO:0030176,GO:0031090,GO:0031224,GO:0031227,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031965,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0031984,GO:0036211,GO:0042175,GO:0042221,GO:0042578,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044432,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046686,GO:0046906,GO:0046907,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051169,GO:0051171,GO:0051172,GO:0051179,GO:0051193,GO:0051195,GO:0051234,GO:0051641,GO:0051649,GO:0051716,GO:0055044,GO:0065007,GO:0070013,GO:0071214,GO:0071478,GO:0071482,GO:0071489,GO:0071704,GO:0090056,GO:0097159,GO:0098827,GO:0104004,GO:0140096,GO:1901363,GO:1901401,GO:1901402,GO:1901463,GO:1901464,GO:1901564,GO:1902325 3.1.3.16 0.000001913 59.0
HFD2_k127_5549328_16 Tetratricopeptide repeat - - - 0.00006565 56.0
HFD2_k127_5549328_2 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 431.0
HFD2_k127_5549328_3 Peptidase S9 prolyl oligopeptidase active site domain protein K01303 - 3.4.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 365.0
HFD2_k127_5549328_4 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002632 295.0
HFD2_k127_5549328_5 e3 binding domain K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000006958 253.0
HFD2_k127_5549328_6 Amidohydrolase family K20810 - 3.5.4.40 0.000000000000000000000000000000000000000000000000000000000000000000005794 249.0
HFD2_k127_5549328_7 serine-type endopeptidase activity K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000001177 244.0
HFD2_k127_5549328_8 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000004168 218.0
HFD2_k127_5549328_9 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K07081,K11782,K11784 - 1.21.98.1,4.2.1.151 0.000000000000000000000000000000000000000000000000000000007915 221.0
HFD2_k127_5550522_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 3.138e-214 678.0
HFD2_k127_5550522_1 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 4.756e-204 643.0
HFD2_k127_5550522_10 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 486.0
HFD2_k127_5550522_11 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006186 441.0
HFD2_k127_5550522_12 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006638 472.0
HFD2_k127_5550522_13 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008303 449.0
HFD2_k127_5550522_14 Protein of unknown function (DUF1343) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 421.0
HFD2_k127_5550522_15 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 436.0
HFD2_k127_5550522_16 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005953 385.0
HFD2_k127_5550522_17 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 347.0
HFD2_k127_5550522_18 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 342.0
HFD2_k127_5550522_19 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 327.0
HFD2_k127_5550522_2 Beta-lactamase class C - - - 2.078e-203 652.0
HFD2_k127_5550522_20 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004059 329.0
HFD2_k127_5550522_21 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005881 287.0
HFD2_k127_5550522_22 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 296.0
HFD2_k127_5550522_23 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000023 288.0
HFD2_k127_5550522_24 phospholipase C - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005931 278.0
HFD2_k127_5550522_25 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000009055 268.0
HFD2_k127_5550522_26 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000001168 283.0
HFD2_k127_5550522_27 Cytochrome C biogenesis protein transmembrane region K06196,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000003983 259.0
HFD2_k127_5550522_28 CO dehydrogenase flavoprotein C-terminal domain K11178 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000042 279.0
HFD2_k127_5550522_29 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006556 272.0
HFD2_k127_5550522_3 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K11177 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009002 604.0
HFD2_k127_5550522_30 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817,K04720 - 2.6.1.9,4.1.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000167 270.0
HFD2_k127_5550522_31 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000009224 262.0
HFD2_k127_5550522_32 imidazoleglycerol-phosphate dehydratase activity K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000002174 255.0
HFD2_k127_5550522_33 TIGR00266 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000112 233.0
HFD2_k127_5550522_34 Belongs to the TrpC family K01609 - 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000132 243.0
HFD2_k127_5550522_35 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.0000000000000000000000000000000000000000000000000000000000001663 228.0
HFD2_k127_5550522_36 TIGRFAM Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000003417 228.0
HFD2_k127_5550522_37 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000005037 218.0
HFD2_k127_5550522_38 [2Fe-2S] binding domain K03518,K13483 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000001669 216.0
HFD2_k127_5550522_39 aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000001138 231.0
HFD2_k127_5550522_4 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003559 568.0
HFD2_k127_5550522_40 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000006771 212.0
HFD2_k127_5550522_41 Belongs to the peptidase S41A family - - - 0.000000000000000000000000000000000000000000000000000002791 207.0
HFD2_k127_5550522_42 Phosphoribosyl-AMP cyclohydrolase K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000000003556 201.0
HFD2_k127_5550522_43 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000003853 200.0
HFD2_k127_5550522_44 Patatin-like phospholipase - - - 0.00000000000000000000000000000000000000000000000001279 195.0
HFD2_k127_5550522_45 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000001038 201.0
HFD2_k127_5550522_46 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000002009 196.0
HFD2_k127_5550522_47 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000003049 194.0
HFD2_k127_5550522_48 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765,K02502 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000374 191.0
HFD2_k127_5550522_49 Multidrug transporter K08161 - - 0.0000000000000000000000000000000000000000000001257 187.0
HFD2_k127_5550522_5 3-oxoacid CoA-transferase, a subunit K01027,K01028,K01031,K01034 - 2.8.3.5,2.8.3.6,2.8.3.8,2.8.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000364 559.0
HFD2_k127_5550522_50 - - - - 0.00000000000000000000000000000000000000000002178 169.0
HFD2_k127_5550522_51 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000009324 183.0
HFD2_k127_5550522_52 ECF sigma factor - - - 0.000000000000000000000000000000000000001222 164.0
HFD2_k127_5550522_53 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000000000000000000000000000000002082 166.0
HFD2_k127_5550522_54 PFAM helix-turn-helix- domain containing protein, AraC type - - - 0.0000000000000000000000000000000000006307 151.0
HFD2_k127_5550522_55 - - - - 0.000000000000000000000000000000000001779 155.0
HFD2_k127_5550522_56 Protein of unknown function (DUF1579) - - - 0.000000000000000000000000000000000004626 144.0
HFD2_k127_5550522_57 COG3209 Rhs family protein K06887 - - 0.000000000000000000000000000000002482 137.0
HFD2_k127_5550522_58 Prephenate dehydrogenase K00210,K04517 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12 0.000000000000000000000000000000007066 142.0
HFD2_k127_5550522_59 WD40-like Beta Propeller Repeat K03641 - - 0.0000000000000000000000000001328 134.0
HFD2_k127_5550522_6 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 520.0
HFD2_k127_5550522_60 Thioredoxin-like - - - 0.000000000000000000000000000494 121.0
HFD2_k127_5550522_62 LamG domain protein jellyroll fold domain protein - - - 0.0000000000000000000000002803 118.0
HFD2_k127_5550522_63 - - - - 0.000000000000000000000001179 117.0
HFD2_k127_5550522_65 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000008493 109.0
HFD2_k127_5550522_66 COGs COG1522 Transcriptional regulators K03719 - - 0.0000000000000000000001922 104.0
HFD2_k127_5550522_67 PFAM transcriptional coactivator pterin dehydratase K01724 - 4.2.1.96 0.0000000000000000000003111 102.0
HFD2_k127_5550522_68 - K01865 - 5.4.4.1 0.000000000000000000003807 99.0
HFD2_k127_5550522_69 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.00000000000000000005248 103.0
HFD2_k127_5550522_7 phosphoribosylamine-glycine ligase activity K01919 - 6.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 522.0
HFD2_k127_5550522_70 Chorismate mutase type II - - - 0.000000000000000006713 96.0
HFD2_k127_5550522_71 - - - - 0.0000000000000001878 91.0
HFD2_k127_5550522_72 oxidoreductase activity - - - 0.0000000000000007614 92.0
HFD2_k127_5550522_73 SMI1-KNR4 cell-wall - - - 0.00000000000001845 79.0
HFD2_k127_5550522_74 nuclear chromosome segregation - - - 0.00000000000001943 84.0
HFD2_k127_5550522_75 von Willebrand factor, type A K07114 - - 0.00000000000004116 86.0
HFD2_k127_5550522_77 - - - - 0.000000000006074 68.0
HFD2_k127_5550522_78 - - - - 0.00000000005365 65.0
HFD2_k127_5550522_79 - - - - 0.00000000008125 71.0
HFD2_k127_5550522_8 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 488.0
HFD2_k127_5550522_80 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000001275 74.0
HFD2_k127_5550522_81 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000002 67.0
HFD2_k127_5550522_82 PilZ domain - - - 0.000000007162 63.0
HFD2_k127_5550522_83 - - - - 0.00000001422 68.0
HFD2_k127_5550522_84 Fic/DOC family - GO:0000166,GO:0003008,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005737,GO:0005783,GO:0005789,GO:0005886,GO:0006464,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006836,GO:0006950,GO:0006952,GO:0007600,GO:0007601,GO:0007610,GO:0007632,GO:0008081,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009416,GO:0009581,GO:0009582,GO:0009583,GO:0009584,GO:0009605,GO:0009607,GO:0009617,GO:0009628,GO:0009966,GO:0009987,GO:0010646,GO:0012505,GO:0015696,GO:0016020,GO:0016021,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0017076,GO:0018117,GO:0018175,GO:0019538,GO:0023051,GO:0030176,GO:0030544,GO:0030554,GO:0031072,GO:0031224,GO:0031227,GO:0031967,GO:0031975,GO:0031984,GO:0032501,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034260,GO:0034976,GO:0035639,GO:0036094,GO:0036211,GO:0042175,GO:0042578,GO:0042742,GO:0042802,GO:0042803,GO:0043086,GO:0043087,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044092,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0044601,GO:0044602,GO:0044603,GO:0045117,GO:0046983,GO:0048519,GO:0048583,GO:0050789,GO:0050790,GO:0050794,GO:0050829,GO:0050877,GO:0050896,GO:0050906,GO:0050908,GO:0050953,GO:0050962,GO:0051087,GO:0051179,GO:0051234,GO:0051336,GO:0051346,GO:0051606,GO:0051608,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0065009,GO:0070566,GO:0070733,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0080134,GO:0080135,GO:0097159,GO:0097367,GO:0098542,GO:0098827,GO:0140096,GO:1900101,GO:1901265,GO:1901363,GO:1901564,GO:1903894,GO:1905897 - 0.00000002374 64.0
HFD2_k127_5550522_86 zinc-ribbon domain - - - 0.0000008795 59.0
HFD2_k127_5550522_87 lipolytic protein G-D-S-L family - - - 0.000001168 61.0
HFD2_k127_5550522_88 - - - - 0.000001971 57.0
HFD2_k127_5550522_89 PFAM UBA THIF-type NAD FAD binding K21029 - 2.7.7.80 0.000002467 50.0
HFD2_k127_5550522_9 PLD-like domain K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 469.0
HFD2_k127_5550522_90 (FHA) domain - - - 0.0002136 55.0
HFD2_k127_5550522_91 von Willebrand factor type A domain - - - 0.0006352 52.0
HFD2_k127_5550522_92 - - - - 0.0008313 49.0
HFD2_k127_5553778_0 ATP dependent DNA ligase domain protein K01971 - 6.5.1.1 6.589e-215 683.0
HFD2_k127_5553778_1 aminopeptidase activity K07004 - - 0.00000000000000000000000000000000000000003784 168.0
HFD2_k127_5554041_0 PFAM ABC transporter transmembrane K06147 - - 2.244e-258 825.0
HFD2_k127_5554041_1 Peptidase S46 - - - 9.414e-220 702.0
HFD2_k127_5554041_10 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000002477 171.0
HFD2_k127_5554041_11 AntiSigma factor - - - 0.00000000000000000000000000000000000001176 160.0
HFD2_k127_5554041_12 Sortase family K07284 - 3.4.22.70 0.0000000000000000000000000000009818 131.0
HFD2_k127_5554041_13 - - - - 0.000000000000000000000004867 105.0
HFD2_k127_5554041_14 response regulator, receiver - - - 0.0000000000000007998 85.0
HFD2_k127_5554041_15 Cyclic nucleotide-monophosphate binding domain K04739 - - 0.000000000000002817 88.0
HFD2_k127_5554041_16 Endoribonuclease L-PSP - - - 0.000000000002159 81.0
HFD2_k127_5554041_17 Endoribonuclease L-PSP - - - 0.00000000005992 76.0
HFD2_k127_5554041_18 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000007903 76.0
HFD2_k127_5554041_19 exo-alpha-(2->6)-sialidase activity - - - 0.0000000002685 64.0
HFD2_k127_5554041_2 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.415e-208 655.0
HFD2_k127_5554041_20 Tetratricopeptide repeats - - - 0.000004083 59.0
HFD2_k127_5554041_3 nuclear chromosome segregation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009494 514.0
HFD2_k127_5554041_4 PA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 434.0
HFD2_k127_5554041_5 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004485 404.0
HFD2_k127_5554041_6 Caspase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004528 343.0
HFD2_k127_5554041_7 Caspase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 342.0
HFD2_k127_5554041_8 FAD binding domain K00103,K00279 - 1.1.3.8,1.5.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 302.0
HFD2_k127_5554041_9 PFAM Acyl-ACP thioesterase - - - 0.00000000000000000000000000000000000000000000006189 183.0
HFD2_k127_5576942_0 Oxidoreductase - - - 1.313e-249 794.0
HFD2_k127_5576942_1 Putative carbohydrate binding domain K12373 - 3.2.1.52 1.394e-199 639.0
HFD2_k127_5576942_2 PFAM nucleoside H symporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 476.0
HFD2_k127_5576942_3 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 331.0
HFD2_k127_5576942_4 DUF218 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000008046 237.0
HFD2_k127_5576942_5 Gluconate 2-dehydrogenase subunit 3 - - - 0.0000000000000000000000000000000000000000000001241 192.0
HFD2_k127_5576942_6 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000008817 109.0
HFD2_k127_5576942_7 Cytochrome c - - - 0.0001873 51.0
HFD2_k127_5576942_8 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR - - - 0.00026 51.0
HFD2_k127_5594530_0 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 607.0
HFD2_k127_5594530_1 cytochrome C peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007292 532.0
HFD2_k127_5594530_10 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 326.0
HFD2_k127_5594530_11 HEAT repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002303 292.0
HFD2_k127_5594530_12 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K16843 - 1.1.1.310 0.000000000000000000000000000000000000000000000000000000000638 218.0
HFD2_k127_5594530_13 Enoyl-CoA hydratase isomerase K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000004651 207.0
HFD2_k127_5594530_14 helix_turn_helix, Lux Regulon K02479 - - 0.000000000000000000000000000000000000000000000000008799 203.0
HFD2_k127_5594530_15 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000005522 180.0
HFD2_k127_5594530_16 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000003115 184.0
HFD2_k127_5594530_17 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0000000000000000000000000000000000000000004896 168.0
HFD2_k127_5594530_18 TIGRFAM addiction module toxin, Txe YoeB family K19158 - - 0.000000000000000000000000000000000000000002387 156.0
HFD2_k127_5594530_19 - - - - 0.0000000000000000000000000000000000000001932 163.0
HFD2_k127_5594530_2 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000392 544.0
HFD2_k127_5594530_20 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000001003 166.0
HFD2_k127_5594530_21 Sel1-like repeats. K07126 - - 0.00000000000000000000000000000000001061 153.0
HFD2_k127_5594530_22 Metallo-peptidase family M12 - - - 0.0000000000000000000000000000000006062 151.0
HFD2_k127_5594530_23 Cytochrome c biogenesis protein - - - 0.000000000000000000000000000000001383 151.0
HFD2_k127_5594530_24 PBS lyase HEAT-like repeat - - - 0.000000000000000000000000000000004466 144.0
HFD2_k127_5594530_25 Antitoxin component of a toxin-antitoxin (TA) module K19159 - - 0.000000000000000000000008394 104.0
HFD2_k127_5594530_27 cell adhesion involved in biofilm formation K12057 - - 0.0000001346 64.0
HFD2_k127_5594530_29 PFAM TPR repeat-containing protein - - - 0.00001472 55.0
HFD2_k127_5594530_3 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 536.0
HFD2_k127_5594530_30 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K02573 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0004055 49.0
HFD2_k127_5594530_31 - - - - 0.0006487 51.0
HFD2_k127_5594530_32 PFAM sigma-54 factor interaction domain-containing protein K21405 - - 0.0007191 49.0
HFD2_k127_5594530_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009314 391.0
HFD2_k127_5594530_5 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 364.0
HFD2_k127_5594530_6 ABC-type transport system involved in cytochrome c biogenesis permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 374.0
HFD2_k127_5594530_7 Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 370.0
HFD2_k127_5594530_8 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 359.0
HFD2_k127_5594530_9 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004236 351.0
HFD2_k127_5631124_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 2.817e-254 809.0
HFD2_k127_5631124_1 WD40-like Beta Propeller Repeat K03641,K07277 - - 2.375e-199 656.0
HFD2_k127_5631124_10 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000005591 123.0
HFD2_k127_5631124_11 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000003562 111.0
HFD2_k127_5631124_12 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000001553 115.0
HFD2_k127_5631124_13 S1 P1 Nuclease - - - 0.000000000000000000000002313 113.0
HFD2_k127_5631124_14 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000000000001846 104.0
HFD2_k127_5631124_16 AntiSigma factor K03088 - - 0.0004026 45.0
HFD2_k127_5631124_2 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 542.0
HFD2_k127_5631124_3 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 356.0
HFD2_k127_5631124_4 PFAM sigma-54 factor interaction domain-containing protein K02481,K07714,K10943 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004221 283.0
HFD2_k127_5631124_5 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000052 269.0
HFD2_k127_5631124_6 TIGRFAM DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000006408 235.0
HFD2_k127_5631124_7 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000164 151.0
HFD2_k127_5631124_8 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.0000000000000000000000000000000000002347 159.0
HFD2_k127_5631124_9 PFAM Phosphoribosyltransferase K02242 - - 0.00000000000000000000000000000000001657 149.0
HFD2_k127_565721_0 Carboxypeptidase regulatory-like domain - - - 0.0 1047.0
HFD2_k127_565721_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006771 320.0
HFD2_k127_565721_2 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 307.0
HFD2_k127_565721_3 arylsulfatase A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002995 286.0
HFD2_k127_565721_4 TIGRFAM VWFA-related Acidobacterial domain - - - 0.000000000000000000000000000006296 138.0
HFD2_k127_565721_5 - - - - 0.0000001245 60.0
HFD2_k127_5659568_0 Succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1045.0
HFD2_k127_5659568_1 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007363 391.0
HFD2_k127_5659568_2 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002079 269.0
HFD2_k127_5659568_3 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000001502 254.0
HFD2_k127_5659568_4 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.00000000000000000000000000000000000000000000000000000000000002727 227.0
HFD2_k127_5659568_5 - K00241 - - 0.00000000000000000000000000000000000000000000000000000000001152 216.0
HFD2_k127_5659568_6 Lecithin:cholesterol acyltransferase - - - 0.0000000000000000000000000000000000000000000002285 185.0
HFD2_k127_5659568_7 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000001551 121.0
HFD2_k127_5659568_8 response regulator receiver K20977 - - 0.000000000000000001133 100.0
HFD2_k127_5659568_9 - - - - 0.000000000000009196 79.0
HFD2_k127_5696392_0 synthase K00705,K06044 GO:0000272,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009251,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016052,GO:0016853,GO:0016866,GO:0030978,GO:0030980,GO:0034637,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0047470,GO:0071704,GO:1901575,GO:1901576 2.4.1.25,5.4.99.15 1.922e-311 978.0
HFD2_k127_5696392_1 Belongs to the glycosyl hydrolase 13 family K01200,K01214 - 3.2.1.41,3.2.1.68 7.959e-309 960.0
HFD2_k127_5696392_10 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001333 308.0
HFD2_k127_5696392_11 amino acid K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003104 263.0
HFD2_k127_5696392_12 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000001804 244.0
HFD2_k127_5696392_13 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000008146 247.0
HFD2_k127_5696392_14 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000004747 232.0
HFD2_k127_5696392_15 FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000086 213.0
HFD2_k127_5696392_16 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000005267 218.0
HFD2_k127_5696392_17 peptide deformylase activity K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.000000000000000000000000000000000000000000000002146 192.0
HFD2_k127_5696392_18 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000004946 169.0
HFD2_k127_5696392_19 - - - - 0.0000000000000000000000000000000000000001607 158.0
HFD2_k127_5696392_2 NHLM bacteriocin system ABC transporter, peptidase ATP-binding protein - - - 3.054e-262 835.0
HFD2_k127_5696392_20 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.00000000000000000000000000000000000302 145.0
HFD2_k127_5696392_21 PDZ DHR GLGF domain protein - - - 0.0000000000000000000000000000000001576 143.0
HFD2_k127_5696392_22 PDZ DHR GLGF domain protein - - - 0.000000000000000000000000000000004415 143.0
HFD2_k127_5696392_23 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000009306 145.0
HFD2_k127_5696392_24 Iron--sulfur cluster insertion protein erpA K15724 - - 0.000000000000000000000000000003586 128.0
HFD2_k127_5696392_25 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000001024 93.0
HFD2_k127_5696392_26 2OG-Fe(II) oxygenase superfamily - - - 0.00000000000000000002685 106.0
HFD2_k127_5696392_27 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000009441 105.0
HFD2_k127_5696392_28 Outer membrane efflux protein - - - 0.00000000000000001764 96.0
HFD2_k127_5696392_29 His Kinase A (phosphoacceptor) domain - - - 0.00000000004468 76.0
HFD2_k127_5696392_3 Peptidase C39 family K06147 - - 6.989e-203 672.0
HFD2_k127_5696392_30 high-affinity sulfate:proton symporter activity K06203 GO:0000096,GO:0000097,GO:0000103,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0008150,GO:0008152,GO:0008271,GO:0008272,GO:0008324,GO:0008509,GO:0008512,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009675,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015103,GO:0015116,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015296,GO:0015318,GO:0015672,GO:0015698,GO:0016020,GO:0016021,GO:0016053,GO:0019344,GO:0019752,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044425,GO:0044459,GO:0044464,GO:0046394,GO:0051179,GO:0051234,GO:0055085,GO:0071704,GO:0071944,GO:0072348,GO:0098655,GO:0098656,GO:0098660,GO:0098661,GO:0098662,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901682,GO:1902358,GO:1902600 - 0.0000000001308 72.0
HFD2_k127_5696392_31 - - - - 0.00000006319 65.0
HFD2_k127_5696392_32 - - - - 0.00000007685 65.0
HFD2_k127_5696392_33 Nitrile hydratase - - - 0.00005258 49.0
HFD2_k127_5696392_4 Lanthionine synthetase C-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005338 583.0
HFD2_k127_5696392_5 Zinc carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005732 513.0
HFD2_k127_5696392_6 Aminoglycoside phosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007792 464.0
HFD2_k127_5696392_7 Belongs to the bacterial plant glucose-1-phosphate adenylyltransferase family K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 442.0
HFD2_k127_5696392_8 major pilin protein fima - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004975 387.0
HFD2_k127_5696392_9 Macrocin-O-methyltransferase (TylF) K05303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000123 286.0
HFD2_k127_574513_0 Histidine kinase K07716,K20974 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009288 554.0
HFD2_k127_574513_1 response regulator, receiver K01120 - 3.1.4.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004136 547.0
HFD2_k127_574513_10 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000001878 153.0
HFD2_k127_574513_11 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000002391 153.0
HFD2_k127_574513_12 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000008284 148.0
HFD2_k127_574513_13 Polyketide cyclase dehydrase - - - 0.00000000000000000000000000000001103 139.0
HFD2_k127_574513_14 heat shock protein binding - - - 0.00000000000000000000000000000009386 139.0
HFD2_k127_574513_15 Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure - - - 0.000000000000000000000000000003549 122.0
HFD2_k127_574513_16 Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth - - - 0.00000000000000000000000466 105.0
HFD2_k127_574513_17 Glycosyl transferase, family 2 - - - 0.000000000000002055 89.0
HFD2_k127_574513_18 ABC-type multidrug transport system ATPase component - - - 0.0000000000001781 82.0
HFD2_k127_574513_2 heat shock protein binding K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000807 328.0
HFD2_k127_574513_20 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0005608 54.0
HFD2_k127_574513_3 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005856 298.0
HFD2_k127_574513_4 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000000000259 228.0
HFD2_k127_574513_5 Arsenical pump-driving ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000014 180.0
HFD2_k127_574513_6 HAD-hyrolase-like K01091 - 3.1.3.18 0.000000000000000000000000000000000000002552 162.0
HFD2_k127_574513_7 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000002971 166.0
HFD2_k127_574513_9 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000004455 144.0
HFD2_k127_5762668_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 383.0
HFD2_k127_5762668_1 Transmembrane protein 43 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 336.0
HFD2_k127_5762668_10 Class III cytochrome C family - - - 0.00000005309 66.0
HFD2_k127_5762668_11 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000009433 62.0
HFD2_k127_5762668_2 Thioredoxin - - - 0.0000000000000000000000000000000000000000000000000000000002995 215.0
HFD2_k127_5762668_3 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000009537 177.0
HFD2_k127_5762668_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00798 - 2.5.1.17 0.000000000000000000000000000000000000000002414 160.0
HFD2_k127_5762668_5 amino acid activation for nonribosomal peptide biosynthetic process K03641,K20276 - - 0.00000000000000000000000000000000000000002017 176.0
HFD2_k127_5762668_6 PFAM Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000008991 129.0
HFD2_k127_5762668_7 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000001401 118.0
HFD2_k127_5762668_8 - - - - 0.000000000000005481 87.0
HFD2_k127_5762668_9 Multicopper oxidase K00368,K07233,K22349 - 1.16.3.3,1.7.2.1 0.00000000003176 77.0
HFD2_k127_5804544_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002676 380.0
HFD2_k127_5804544_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 327.0
HFD2_k127_5804544_2 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004366 318.0
HFD2_k127_5804544_3 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000000000232 203.0
HFD2_k127_5832575_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1027.0
HFD2_k127_5832575_1 MutS domain I K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 7.302e-249 796.0
HFD2_k127_5832575_10 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005718 388.0
HFD2_k127_5832575_11 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006286 382.0
HFD2_k127_5832575_12 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007225 364.0
HFD2_k127_5832575_13 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 318.0
HFD2_k127_5832575_14 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 302.0
HFD2_k127_5832575_15 Putative ATP-binding cassette K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007506 313.0
HFD2_k127_5832575_16 anion transmembrane transporter activity K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000962 279.0
HFD2_k127_5832575_17 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001971 268.0
HFD2_k127_5832575_18 Serine phosphatase RsbU regulator of sigma subunit K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000006734 269.0
HFD2_k127_5832575_19 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000143 246.0
HFD2_k127_5832575_2 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003778 613.0
HFD2_k127_5832575_20 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000000000000000000000000000000000364 235.0
HFD2_k127_5832575_21 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000004042 213.0
HFD2_k127_5832575_22 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000004681 229.0
HFD2_k127_5832575_23 PFAM transglutaminase domain protein - - - 0.00000000000000000000000000000000000000000000000000000005777 216.0
HFD2_k127_5832575_24 cyclic nucleotide binding K10914 - - 0.000000000000000000000000000000000000000000000000005315 188.0
HFD2_k127_5832575_25 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 GO:0000049,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.7.7.87 0.0000000000000000000000000000000000002984 149.0
HFD2_k127_5832575_26 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 - 2.1.1.200 0.000000000000000000000000000000000003723 160.0
HFD2_k127_5832575_27 ABC nitrate sulphonate bicarbonate family transporter, ATPase subunit K02049 - - 0.0000000000000000000000000002613 121.0
HFD2_k127_5832575_28 Belongs to the Nudix hydrolase family - - - 0.000000000000000000000000001006 128.0
HFD2_k127_5832575_29 Ion transport protein K10716 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944 - 0.000000000000000000000000006701 119.0
HFD2_k127_5832575_3 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 541.0
HFD2_k127_5832575_30 STAS domain K04749,K06378 - - 0.00000000000000000000000006021 111.0
HFD2_k127_5832575_31 Glycoprotease family K01409,K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.000000000000000000000005814 111.0
HFD2_k127_5832575_32 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000002521 105.0
HFD2_k127_5832575_33 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.000000000000000000001096 108.0
HFD2_k127_5832575_34 - - - - 0.000000000000000000001309 103.0
HFD2_k127_5832575_35 cell adhesion involved in biofilm formation - - - 0.00000000000000000007669 103.0
HFD2_k127_5832575_36 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000013 94.0
HFD2_k127_5832575_37 sigma factor antagonist activity K04757,K17752 - 2.7.11.1 0.00000000000000002174 88.0
HFD2_k127_5832575_38 E-Z type HEAT repeats - - - 0.00000000000000008686 94.0
HFD2_k127_5832575_39 PFAM SNARE associated Golgi protein - - - 0.0000000000000002154 91.0
HFD2_k127_5832575_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 483.0
HFD2_k127_5832575_40 Belongs to the small heat shock protein (HSP20) family - - - 0.000000000000008559 79.0
HFD2_k127_5832575_41 PspA/IM30 family K03969 - - 0.00000000002551 77.0
HFD2_k127_5832575_42 phytanoyl-CoA dioxygenase K07053 - 3.1.3.97 0.000000001841 71.0
HFD2_k127_5832575_43 Protein of unknown function (DUF465) - - - 0.0000001569 59.0
HFD2_k127_5832575_45 S-layer homology domain - - - 0.000001193 61.0
HFD2_k127_5832575_5 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 469.0
HFD2_k127_5832575_6 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007359 473.0
HFD2_k127_5832575_7 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003131 450.0
HFD2_k127_5832575_8 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 443.0
HFD2_k127_5832575_9 response regulator K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 408.0
HFD2_k127_5833049_0 Tricorn protease homolog K08676 - - 0.0 1076.0
HFD2_k127_5833049_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.407e-270 841.0
HFD2_k127_5833049_10 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244 - 1.4.1.1,4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 330.0
HFD2_k127_5833049_11 Pyridoxal-phosphate dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008843 329.0
HFD2_k127_5833049_12 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004287 315.0
HFD2_k127_5833049_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001826 284.0
HFD2_k127_5833049_14 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004421 273.0
HFD2_k127_5833049_15 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000007116 247.0
HFD2_k127_5833049_16 Proline dehydrogenase K00318 - - 0.0000000000000000000000000000000000000000000000000000000000000002983 231.0
HFD2_k127_5833049_17 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000002753 211.0
HFD2_k127_5833049_18 O-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000001165 199.0
HFD2_k127_5833049_19 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000000000000001418 201.0
HFD2_k127_5833049_2 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007841 588.0
HFD2_k127_5833049_20 methyltransferase activity - - - 0.00000000000000000000000000000000000000000001379 175.0
HFD2_k127_5833049_21 CoA binding domain - - - 0.00000000000000000000000000000000000000005377 163.0
HFD2_k127_5833049_22 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.000000000000000000000000000000000000000556 167.0
HFD2_k127_5833049_23 protein conserved in bacteria - - - 0.000000000000000000000000000000000003763 141.0
HFD2_k127_5833049_24 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000001449 141.0
HFD2_k127_5833049_25 VIT family - - - 0.00000000000000000000000009372 115.0
HFD2_k127_5833049_26 4-amino-4-deoxy-L-arabinose transferase activity K16648 - - 0.00000000000000003166 97.0
HFD2_k127_5833049_27 TIGRFAM Caa(3)-type oxidase, subunit IV K02277 - 1.9.3.1 0.000000000000003804 87.0
HFD2_k127_5833049_28 OsmC-like protein K07397 - - 0.0000000000000258 87.0
HFD2_k127_5833049_29 Rhomboid family - - - 0.00000000000007289 79.0
HFD2_k127_5833049_3 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 463.0
HFD2_k127_5833049_30 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000000006063 62.0
HFD2_k127_5833049_31 sporulation resulting in formation of a cellular spore K01173,K21449 - - 0.00000006755 63.0
HFD2_k127_5833049_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003888 446.0
HFD2_k127_5833049_5 Zn-dependent dipeptidase, microsomal dipeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 423.0
HFD2_k127_5833049_6 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002737 387.0
HFD2_k127_5833049_7 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 411.0
HFD2_k127_5833049_8 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006114 360.0
HFD2_k127_5833049_9 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005973 349.0
HFD2_k127_5834393_0 3-isopropylmalate dehydratase activity K01703 - 4.2.1.33,4.2.1.35 3.812e-208 654.0
HFD2_k127_5834393_1 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 571.0
HFD2_k127_5834393_10 Glycine cleavage H-protein - - - 0.0000000000000119 84.0
HFD2_k127_5834393_11 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 GO:0001505,GO:0003674,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0017144,GO:0019464,GO:0019752,GO:0031405,GO:0031406,GO:0033293,GO:0036094,GO:0042133,GO:0042135,GO:0042737,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901681 - 0.00000000000003864 85.0
HFD2_k127_5834393_2 Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 528.0
HFD2_k127_5834393_3 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008557 529.0
HFD2_k127_5834393_4 HMGL-like K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 344.0
HFD2_k127_5834393_5 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004281 322.0
HFD2_k127_5834393_6 Uncharacterised protein family UPF0066 - - - 0.00000000000000000000000000000000000000000000000000000000000000000003599 236.0
HFD2_k127_5834393_7 3-isopropylmalate dehydratase activity K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000003556 215.0
HFD2_k127_5834393_8 Glycine cleavage H-protein - - - 0.00000000000000000000000000000000000000000000000000889 188.0
HFD2_k127_5834393_9 HAMP domain K02482 - 2.7.13.3 0.000000000000007115 82.0
HFD2_k127_5841665_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 2.258e-263 833.0
HFD2_k127_5841665_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.571e-233 742.0
HFD2_k127_5841665_2 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000006469 250.0
HFD2_k127_5841665_3 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000002141 112.0
HFD2_k127_5841665_4 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000003548 126.0
HFD2_k127_5841665_5 Protein of unknown function (DUF503) K09764 - - 0.0000000000000000005251 89.0
HFD2_k127_5841665_6 - - - - 0.0000483 56.0
HFD2_k127_5844832_0 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 3.8e-292 912.0
HFD2_k127_5844832_1 Glutamine synthetase type III N terminal K01915 - 6.3.1.2 2.799e-249 789.0
HFD2_k127_5844832_10 - - - - 0.0000000000000000000000000000000000000000001453 162.0
HFD2_k127_5844832_11 Mannose-6-phosphate isomerase - - - 0.0000000000000000000000000000000000000000001817 161.0
HFD2_k127_5844832_12 Protein of Unknown function (DUF2784) - - - 0.000000000000000000000000000000003391 137.0
HFD2_k127_5844832_13 - - - - 0.00000000000000000000000008083 112.0
HFD2_k127_5844832_14 COG2893 Phosphotransferase system, mannose fructose-specific component IIA K02793 - 2.7.1.191 0.00000000000000000000000245 117.0
HFD2_k127_5844832_15 Methyltransferase - - - 0.0000000000000000000001246 106.0
HFD2_k127_5844832_16 YceI-like domain - - - 0.0000000000000000000003249 106.0
HFD2_k127_5844832_17 COG1925 Phosphotransferase system, HPr-related proteins K08485,K11189 GO:0003674,GO:0003824,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006808,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0009401,GO:0009987,GO:0010033,GO:0010243,GO:0016310,GO:0016740,GO:0016772,GO:0019538,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050896,GO:0051179,GO:0051234,GO:0065007,GO:0071702,GO:0071704,GO:1901564,GO:1901698 - 0.000000000000000000005952 98.0
HFD2_k127_5844832_18 Ribosomal subunit interface protein K05808 - - 0.00000000002195 70.0
HFD2_k127_5844832_19 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000168 47.0
HFD2_k127_5844832_2 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003147 444.0
HFD2_k127_5844832_20 OstA-like protein K09774 - - 0.0009156 53.0
HFD2_k127_5844832_3 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006383 453.0
HFD2_k127_5844832_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008626 415.0
HFD2_k127_5844832_5 PFAM ABC transporter related K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005475 318.0
HFD2_k127_5844832_6 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 317.0
HFD2_k127_5844832_7 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000139 296.0
HFD2_k127_5844832_8 Glucose inhibited division protein A K21401 - 1.3.99.38 0.00000000000000000000000000000000000000000000000000000000000000000000000001897 268.0
HFD2_k127_5844832_9 synthase K16167 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006629,GO:0006725,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009273,GO:0009698,GO:0009699,GO:0009714,GO:0009715,GO:0009987,GO:0016020,GO:0016043,GO:0019438,GO:0019748,GO:0022607,GO:0032991,GO:0034081,GO:0042180,GO:0042181,GO:0042546,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0071554,GO:0071704,GO:0071766,GO:0071770,GO:0071840,GO:0071944,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000008365 256.0
HFD2_k127_5845541_0 glutamate synthase activity K00265,K00284,K22083 GO:0003674,GO:0003824,GO:0004355,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045181,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1,2.1.1.21 0.0 1939.0
HFD2_k127_5845541_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 9.4e-323 1005.0
HFD2_k127_5845541_10 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000004309 206.0
HFD2_k127_5845541_11 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000006655 157.0
HFD2_k127_5845541_12 radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000007869 141.0
HFD2_k127_5845541_13 cytochrome - - - 0.00000000000000000000000000000000001344 141.0
HFD2_k127_5845541_14 MerR, DNA binding - - - 0.0000000000000000000000000000000000775 138.0
HFD2_k127_5845541_15 COG0666 FOG Ankyrin repeat K06867 - - 0.000000000000000000000000000000002197 145.0
HFD2_k127_5845541_16 - - - - 0.000000000000002669 91.0
HFD2_k127_5845541_2 Alkaline phosphatase K01113 - 3.1.3.1 6.579e-283 885.0
HFD2_k127_5845541_3 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006131 390.0
HFD2_k127_5845541_4 radical SAM domain protein K06139 GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0018130,GO:0018189,GO:0018193,GO:0018212,GO:0019538,GO:0019752,GO:0034641,GO:0036211,GO:0042180,GO:0042181,GO:0042364,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072350,GO:0072351,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901661,GO:1901663 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008393 397.0
HFD2_k127_5845541_5 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 353.0
HFD2_k127_5845541_6 Hemolysin-type calcium-binding repeat (2 copies) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009471 323.0
HFD2_k127_5845541_7 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000811 306.0
HFD2_k127_5845541_8 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000846 302.0
HFD2_k127_5845541_9 - - - - 0.00000000000000000000000000000000000000000000000000000000001185 228.0
HFD2_k127_5854933_0 Amidase K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000063 596.0
HFD2_k127_5854933_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 370.0
HFD2_k127_5854933_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007271 273.0
HFD2_k127_5854933_3 Methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000002537 263.0
HFD2_k127_5854933_4 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000004793 212.0
HFD2_k127_5854933_5 DNA glycosylase K03649 - 3.2.2.28 0.0000000000000000000000000006349 116.0
HFD2_k127_5856205_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 6.662e-309 963.0
HFD2_k127_5856205_1 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003655 586.0
HFD2_k127_5856205_10 Uncharacterized conserved protein (DUF2249) - - - 0.0000000000000000000000000000004163 134.0
HFD2_k127_5856205_11 cheY-homologous receiver domain - - - 0.000000000000000000000000000002429 126.0
HFD2_k127_5856205_12 Regulator of chromosome condensation (RCC1) repeat - - - 0.00000000001319 79.0
HFD2_k127_5856205_13 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K01841 - 5.4.2.9 0.00000002256 68.0
HFD2_k127_5856205_2 Serine dehydrogenase proteinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005794 385.0
HFD2_k127_5856205_3 response to heat K03695,K03696,K03697,K03798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001936 282.0
HFD2_k127_5856205_4 Prephenate dehydratase K04518 - 4.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000001084 259.0
HFD2_k127_5856205_5 Amb_all K01728 - 4.2.2.2 0.000000000000000000000000000000000000000000000000000000000000008247 246.0
HFD2_k127_5856205_6 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000001846 231.0
HFD2_k127_5856205_7 SOS response associated peptidase (SRAP) - - - 0.000000000000000000000000000000000000000000000000000000000111 211.0
HFD2_k127_5856205_8 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000000000000000000000000000000000000003211 158.0
HFD2_k127_5856205_9 protein conserved in bacteria - - - 0.0000000000000000000000000000000001396 138.0
HFD2_k127_5863872_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 531.0
HFD2_k127_5863872_1 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007846 325.0
HFD2_k127_5863872_2 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000001331 125.0
HFD2_k127_5863872_3 peptidyl-tyrosine sulfation - - - 0.000000000000000007785 95.0
HFD2_k127_5863872_4 Tetratricopeptide repeats - - - 0.0000001885 63.0
HFD2_k127_5874734_0 Carboxypeptidase regulatory-like domain - - - 0.0 1187.0
HFD2_k127_5874734_1 BtpA family K06971 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009218 274.0
HFD2_k127_5874734_2 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.000000000000000000000000000000003829 135.0
HFD2_k127_5874734_3 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000008273 130.0
HFD2_k127_5874734_4 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.00000001266 61.0
HFD2_k127_5874916_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 1.925e-318 994.0
HFD2_k127_5874916_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 601.0
HFD2_k127_5874916_10 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000001147 232.0
HFD2_k127_5874916_11 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000000000000000000000001508 112.0
HFD2_k127_5874916_12 Uncharacterized ACR, COG1399 K07040 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000003655 108.0
HFD2_k127_5874916_13 Ribosomal L32p protein family K02911 - - 0.0000000000000000000001256 99.0
HFD2_k127_5874916_14 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264 - 0.0000000000000000000001379 114.0
HFD2_k127_5874916_15 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000000009705 89.0
HFD2_k127_5874916_17 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000001717 67.0
HFD2_k127_5874916_2 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 473.0
HFD2_k127_5874916_3 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 344.0
HFD2_k127_5874916_4 electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 311.0
HFD2_k127_5874916_5 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 310.0
HFD2_k127_5874916_6 PFAM Histone deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008971 301.0
HFD2_k127_5874916_7 Belongs to the 'phage' integrase family K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006388 304.0
HFD2_k127_5874916_8 PFAM Short-chain dehydrogenase reductase SDR K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000002283 273.0
HFD2_k127_5874916_9 Electron transfer flavoprotein domain K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008859 250.0
HFD2_k127_5877535_0 Peptidase m28 - - - 4.883e-223 705.0
HFD2_k127_5877535_1 Sodium:solute symporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003938 492.0
HFD2_k127_5877535_10 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002921 282.0
HFD2_k127_5877535_11 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000002209 222.0
HFD2_k127_5877535_12 2 iron, 2 sulfur cluster binding K13643 - - 0.00000000000000000000000000000000000000000000000001845 182.0
HFD2_k127_5877535_13 methyltransferase - - - 0.000000000000000000000000000000000000000000000005858 188.0
HFD2_k127_5877535_14 - - - - 0.000000000000000000000000000000000000000000004956 164.0
HFD2_k127_5877535_15 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000003221 181.0
HFD2_k127_5877535_16 ASCH - - - 0.000000000000000000000000000000000000000001662 159.0
HFD2_k127_5877535_17 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000002691 160.0
HFD2_k127_5877535_18 Lactoylglutathione lyase and related lyases - - - 0.00000000000000000000000000000000000002962 146.0
HFD2_k127_5877535_19 - - - - 0.0000000000000000000000000000000000002153 144.0
HFD2_k127_5877535_2 Amidohydrolase family K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008511 494.0
HFD2_k127_5877535_20 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000005999 134.0
HFD2_k127_5877535_21 DinB family - - - 0.000000000000000000000000000164 129.0
HFD2_k127_5877535_22 DinB superfamily K07552 - - 0.00000000000000000000000000264 125.0
HFD2_k127_5877535_23 DinB family - - - 0.000000000000000000000107 104.0
HFD2_k127_5877535_24 AAA domain - - - 0.00000000000000000001432 104.0
HFD2_k127_5877535_25 - - - - 0.00000000000000000002816 106.0
HFD2_k127_5877535_27 ThiS family K03154 - - 0.00000000000006769 73.0
HFD2_k127_5877535_28 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.000000000001322 74.0
HFD2_k127_5877535_29 DinB superfamily - - - 0.00000000001648 64.0
HFD2_k127_5877535_3 Bacterial extracellular solute-binding protein K02048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009072 500.0
HFD2_k127_5877535_30 Phospholipid methyltransferase - - - 0.00000002064 57.0
HFD2_k127_5877535_4 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004069 456.0
HFD2_k127_5877535_5 ABC transporter permease protein K02047 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004692 382.0
HFD2_k127_5877535_6 ABC transporter permease protein K02046 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 383.0
HFD2_k127_5877535_7 thiamine diphosphate biosynthetic process K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 361.0
HFD2_k127_5877535_8 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004195 308.0
HFD2_k127_5877535_9 Phosphate-selective porin O and P K07221 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001055 298.0
HFD2_k127_5945731_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003742 636.0
HFD2_k127_5945731_1 protein kinase related protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 528.0
HFD2_k127_5945731_10 Phospholipase - - - 0.000000000000000000000000000000000000000000000000000000000000003432 249.0
HFD2_k127_5945731_11 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000598 202.0
HFD2_k127_5945731_12 - - - - 0.000000000000000000000000000000000000000001437 171.0
HFD2_k127_5945731_13 BadF/BadG/BcrA/BcrD ATPase family - - - 0.000000000000000000000002898 119.0
HFD2_k127_5945731_14 Alpha beta hydrolase - - - 0.00000000000005481 84.0
HFD2_k127_5945731_15 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 - - 0.0000000001736 74.0
HFD2_k127_5945731_16 Protein of unknown function (DUF2911) - - - 0.00002685 56.0
HFD2_k127_5945731_2 Aldehyde dehydrogenase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 501.0
HFD2_k127_5945731_3 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002928 495.0
HFD2_k127_5945731_4 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009048 462.0
HFD2_k127_5945731_5 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 350.0
HFD2_k127_5945731_6 FtsX-like permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003201 321.0
HFD2_k127_5945731_7 benzoyl-CoA reductase K04112 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000383 295.0
HFD2_k127_5945731_8 benzoyl-CoA reductase K04113 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005614 301.0
HFD2_k127_5945731_9 Localisation of periplasmic protein complexes K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000847 259.0
HFD2_k127_597160_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 5.937e-274 860.0
HFD2_k127_597160_1 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 428.0
HFD2_k127_597160_10 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000001116 96.0
HFD2_k127_597160_11 peptidyl-tyrosine sulfation - - - 0.00000000000000001464 95.0
HFD2_k127_597160_12 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000002341 60.0
HFD2_k127_597160_2 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009237 406.0
HFD2_k127_597160_3 MotA TolQ ExbB proton channel K03561,K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000001572 228.0
HFD2_k127_597160_4 Ras family - - - 0.0000000000000000000000000000000000000000000000000001846 205.0
HFD2_k127_597160_5 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00000000000000000000000000000000000002546 149.0
HFD2_k127_597160_6 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000000003636 148.0
HFD2_k127_597160_7 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000707 141.0
HFD2_k127_597160_8 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.0000000000000000000005489 108.0
HFD2_k127_597160_9 biopolymer transport protein K03559,K03560 - - 0.000000000000000000003433 98.0
HFD2_k127_6105594_0 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000003957 144.0
HFD2_k127_6166849_0 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 2.008e-254 801.0
HFD2_k127_6166849_1 Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000002086 115.0
HFD2_k127_6166849_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000007081 108.0
HFD2_k127_6181539_0 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001702 254.0
HFD2_k127_6181539_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000005076 198.0
HFD2_k127_6201738_0 PFAM PfkB domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003923 383.0
HFD2_k127_6201738_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 358.0
HFD2_k127_6201738_2 Beta-lactamase K01256,K17836 - 3.4.11.2,3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000002942 252.0
HFD2_k127_6201738_3 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000001037 186.0
HFD2_k127_6201738_4 - - - - 0.0000000000000000000000000000000000000000000000007943 194.0
HFD2_k127_6218625_0 Dehydrogenase K15371 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0008150,GO:0008152,GO:0016491,GO:0016638,GO:0016639,GO:0055114 1.4.1.2 1.096e-272 889.0
HFD2_k127_6218625_1 Aminotransferase class-III K03918,K07250,K20428 - 2.6.1.19,2.6.1.22,2.6.1.33,2.6.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 539.0
HFD2_k127_6218625_10 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 346.0
HFD2_k127_6218625_11 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 347.0
HFD2_k127_6218625_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 319.0
HFD2_k127_6218625_13 Haem-degrading - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 309.0
HFD2_k127_6218625_14 Arginase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006543 289.0
HFD2_k127_6218625_15 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000005477 250.0
HFD2_k127_6218625_16 protein kinase related protein - - - 0.0000000000000000000000000000000000000000000000000000000000000002483 246.0
HFD2_k127_6218625_17 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000005824 244.0
HFD2_k127_6218625_18 NUDIX domain K03574 - 3.6.1.55 0.000000000000000000000000000000000374 143.0
HFD2_k127_6218625_19 Metallo-peptidase family M12 - - - 0.00000000000000000000000000000001491 146.0
HFD2_k127_6218625_2 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 501.0
HFD2_k127_6218625_20 - - - - 0.0000000000000000000000000000002268 123.0
HFD2_k127_6218625_21 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000008376 110.0
HFD2_k127_6218625_22 Protein of unknown function (DUF3311) - - - 0.000000000001713 70.0
HFD2_k127_6218625_23 FHA modulated ABC efflux pump with fused ATPase and integral membrane subunits K01990,K21397 - - 0.000000000002494 78.0
HFD2_k127_6218625_24 DinB family - - - 0.00000004623 66.0
HFD2_k127_6218625_25 VWA domain containing CoxE-like protein - - - 0.00001345 58.0
HFD2_k127_6218625_26 SMART Tetratricopeptide domain protein - - - 0.00006268 55.0
HFD2_k127_6218625_3 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000384 470.0
HFD2_k127_6218625_4 Selenocysteine lyase K04127 - 5.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004314 445.0
HFD2_k127_6218625_5 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003564 428.0
HFD2_k127_6218625_6 Iron-containing alcohol dehydrogenase K00001,K13954 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006109 374.0
HFD2_k127_6218625_7 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 370.0
HFD2_k127_6218625_8 Sodium/calcium exchanger protein K07300 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003866 368.0
HFD2_k127_6218625_9 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 355.0
HFD2_k127_623419_0 helicase K03724 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.0 1262.0
HFD2_k127_623419_1 Protein of unknown function (DUF2891) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005053 508.0
HFD2_k127_623419_10 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001209 261.0
HFD2_k127_623419_12 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000002137 208.0
HFD2_k127_623419_13 Diacylglycerol kinase catalytic domain (presumed) K07029 - 2.7.1.107 0.00000000000000000000000000000000000001517 164.0
HFD2_k127_623419_14 TIGRFAM VWFA-related Acidobacterial domain - - - 0.000000000000000000000000000002113 139.0
HFD2_k127_623419_15 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000004139 127.0
HFD2_k127_623419_16 GtrA-like protein K00995 - 2.7.8.5 0.000000000000000000000000000009731 133.0
HFD2_k127_623419_17 acyltransferase K00655 - 2.3.1.51 0.00000000000000002486 96.0
HFD2_k127_623419_18 lipid kinase activity - - - 0.00000000000000007631 94.0
HFD2_k127_623419_19 bacterial OsmY and nodulation domain - - - 0.00000000000000953 79.0
HFD2_k127_623419_2 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004354 409.0
HFD2_k127_623419_21 LTXXQ motif family protein - - - 0.000000001245 67.0
HFD2_k127_623419_3 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 396.0
HFD2_k127_623419_4 Permease family K06901 GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006863,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015205,GO:0015207,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0015851,GO:0015853,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:0098655,GO:0098660,GO:0098662,GO:1902600,GO:1904823 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 362.0
HFD2_k127_623419_5 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 369.0
HFD2_k127_623419_6 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639,K21784 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008213 340.0
HFD2_k127_623419_7 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 332.0
HFD2_k127_623419_8 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008209 300.0
HFD2_k127_623419_9 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002771 311.0
HFD2_k127_6237_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 6.273e-203 657.0
HFD2_k127_6237_1 TonB-dependent receptor K02014 - - 1.897e-199 658.0
HFD2_k127_6237_10 Phosphate transport system permease protein PstA K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001116 287.0
HFD2_k127_6237_11 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008015 282.0
HFD2_k127_6237_12 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000007587 240.0
HFD2_k127_6237_13 Transcriptional regulatory protein, C terminal K07657 - - 0.000000000000000000000000000000000000000000000000002844 200.0
HFD2_k127_6237_14 Lysylphosphatidylglycerol synthase TM region - - - 0.00000000000000000000000000000000000006781 156.0
HFD2_k127_6237_15 COGs COG1392 Phosphate transport regulator (distant homolog of PhoU) K07220 - - 0.00000000000000000000000000000000003365 154.0
HFD2_k127_6237_16 - - - - 0.000000000000000000000001134 120.0
HFD2_k127_6237_17 TIGRFAM phosphohistidine phosphatase SixA K08296 - - 0.000000000000000000000004983 107.0
HFD2_k127_6237_18 - - - - 0.000000000000000000001384 107.0
HFD2_k127_6237_19 Bacterial protein of unknown function (DUF937) - - - 0.0000000000000000004394 99.0
HFD2_k127_6237_2 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009028 477.0
HFD2_k127_6237_20 Domain of unknown function (DUF309) K09763 - - 0.0000000000000000004888 91.0
HFD2_k127_6237_21 Protein conserved in bacteria - - - 0.0000000000000209 87.0
HFD2_k127_6237_22 CHAD - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0006323 53.0
HFD2_k127_6237_3 Belongs to the PstS family K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007912 425.0
HFD2_k127_6237_4 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 411.0
HFD2_k127_6237_5 Ppx GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004174 398.0
HFD2_k127_6237_6 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007378 400.0
HFD2_k127_6237_7 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 366.0
HFD2_k127_6237_8 Belongs to the PstS family K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 365.0
HFD2_k127_6237_9 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 314.0
HFD2_k127_6261638_0 Sugar (and other) transporter K07058 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 2.963e-228 724.0
HFD2_k127_6261638_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006601 600.0
HFD2_k127_6261638_10 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001647 252.0
HFD2_k127_6261638_11 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.0000000000000000000000000000000000000000004388 162.0
HFD2_k127_6261638_12 - - - - 0.000000000000000000000000000000000006802 145.0
HFD2_k127_6261638_13 - - - - 0.000000000000000000000000001643 129.0
HFD2_k127_6261638_14 SNARE associated Golgi protein - - - 0.0000000003799 61.0
HFD2_k127_6261638_15 - - - - 0.000000001292 71.0
HFD2_k127_6261638_17 response regulator, receiver - - - 0.0004828 53.0
HFD2_k127_6261638_2 Bacterial regulatory protein, Fis family K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 571.0
HFD2_k127_6261638_3 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009677 479.0
HFD2_k127_6261638_4 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005983 432.0
HFD2_k127_6261638_5 Aldo Keto reductase K05882 - 1.1.1.91 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004318 417.0
HFD2_k127_6261638_6 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 420.0
HFD2_k127_6261638_7 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003511 363.0
HFD2_k127_6261638_8 Peptidase S9, prolyl oligopeptidase active site domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005877 326.0
HFD2_k127_6261638_9 PAS domain containing protein K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005078 281.0
HFD2_k127_6280887_0 DEAD DEAH box K03724 - - 0.0 1685.0
HFD2_k127_6280887_1 ABC transporter C-terminal domain K06158 - - 6.536e-198 642.0
HFD2_k127_6280887_10 Pfam:Arch_ATPase - - - 0.0000000000000000000000000000000000000000000000000000000003387 229.0
HFD2_k127_6280887_11 Belongs to the FPG family K05522 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000006034 226.0
HFD2_k127_6280887_12 Alpha/beta hydrolase family K07020 - - 0.0000000000000000000000000000000000000000000000000001177 193.0
HFD2_k127_6280887_13 - K06921 - - 0.00000000000000000000000000000000000000000000000004461 192.0
HFD2_k127_6280887_14 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000001477 178.0
HFD2_k127_6280887_15 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000002668 197.0
HFD2_k127_6280887_16 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000002291 174.0
HFD2_k127_6280887_17 AAA domain - - - 0.00000000000000000000000000000000000000004613 156.0
HFD2_k127_6280887_18 oxidoreductase activity - - - 0.0000000000000000000000000000000000000001805 162.0
HFD2_k127_6280887_19 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000004141 143.0
HFD2_k127_6280887_2 aminopeptidase activity K01266 - 3.4.11.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 443.0
HFD2_k127_6280887_20 - - - - 0.000000000000000000000000007614 121.0
HFD2_k127_6280887_21 TonB dependent receptor K16090 - - 0.0000000000000000000001511 114.0
HFD2_k127_6280887_22 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.00000000000001021 76.0
HFD2_k127_6280887_23 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.0000000004044 68.0
HFD2_k127_6280887_24 Tetratricopeptide repeat - - - 0.00004165 57.0
HFD2_k127_6280887_3 PFAM glycosyl transferase family 51 K05366,K21464 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 393.0
HFD2_k127_6280887_4 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 348.0
HFD2_k127_6280887_5 Cell shape determining protein MreB Mrl - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007157 324.0
HFD2_k127_6280887_6 ATP-dependent DNA helicase RecG K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 323.0
HFD2_k127_6280887_7 AAA domain K02450,K12283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005127 315.0
HFD2_k127_6280887_8 PFAM alanine racemase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001926 297.0
HFD2_k127_6280887_9 N-Acetylmuramoyl-L-alanine amidase K11066,K12287 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000001161 236.0
HFD2_k127_6327983_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 323.0
HFD2_k127_6327983_1 - K01992,K19341 - - 0.000000000000000000001104 104.0
HFD2_k127_6327983_2 peptidyl-tyrosine sulfation - - - 0.00000002383 67.0
HFD2_k127_6363314_0 TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 324.0
HFD2_k127_6363314_1 Y_Y_Y domain - - - 0.0000000000000000000000000000000000000000000000000000000000003212 221.0
HFD2_k127_6363314_2 - - - - 0.0000000007539 64.0
HFD2_k127_6363314_3 peptidyl-tyrosine sulfation - - - 0.0000009344 54.0
HFD2_k127_6387024_0 Response regulator receiver domain - - - 8.611e-267 839.0
HFD2_k127_6387024_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 633.0
HFD2_k127_6387024_10 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000001563 81.0
HFD2_k127_6387024_11 - - - - 0.00000000002096 68.0
HFD2_k127_6387024_13 TonB-dependent receptor - - - 0.000006271 59.0
HFD2_k127_6387024_14 receptor K16087 - - 0.0005317 53.0
HFD2_k127_6387024_2 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 614.0
HFD2_k127_6387024_3 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000669 584.0
HFD2_k127_6387024_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008927 538.0
HFD2_k127_6387024_5 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005639 482.0
HFD2_k127_6387024_6 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K07713,K07714,K19641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004589 498.0
HFD2_k127_6387024_7 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007274 285.0
HFD2_k127_6387024_8 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000001777 149.0
HFD2_k127_6387024_9 response regulator, receiver - - - 0.0000000000000000000000000000000001903 153.0
HFD2_k127_6392502_0 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005882 246.0
HFD2_k127_6392502_1 PMT family glycosyltransferase, 4-amino-4-deoxy-L-arabinose transferase - - - 0.000001944 60.0
HFD2_k127_642063_0 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 462.0
HFD2_k127_642063_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000029 446.0
HFD2_k127_642063_10 transferase activity, transferring glycosyl groups K00721,K03820 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000007638 210.0
HFD2_k127_642063_11 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000001508 226.0
HFD2_k127_642063_12 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000005587 169.0
HFD2_k127_642063_13 HAD-superfamily hydrolase, subfamily IIB - - - 0.000000000000000000000000000000009465 148.0
HFD2_k127_642063_14 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000000000000007521 95.0
HFD2_k127_642063_15 Bacterial membrane protein, YfhO - - - 0.00000000000000005244 97.0
HFD2_k127_642063_16 glycosyl transferase group 1 - - - 0.0000000000000001829 83.0
HFD2_k127_642063_17 Preprotein translocase, YajC K03210 - - 0.000000000002762 72.0
HFD2_k127_642063_18 Peptidase_C39 like family - - - 0.0000000003721 72.0
HFD2_k127_642063_19 PilZ domain - - - 0.000004586 58.0
HFD2_k127_642063_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 441.0
HFD2_k127_642063_3 Beta-eliminating lyase K13010 - 2.6.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004764 362.0
HFD2_k127_642063_4 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 364.0
HFD2_k127_642063_5 PFAM glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 334.0
HFD2_k127_642063_6 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 321.0
HFD2_k127_642063_7 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004375 277.0
HFD2_k127_642063_8 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009742 278.0
HFD2_k127_642063_9 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007524 250.0
HFD2_k127_6508287_0 DEAD DEAH box helicase - - - 0.0 1167.0
HFD2_k127_6508287_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1124.0
HFD2_k127_6508287_10 Peptidase family S41 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006573 286.0
HFD2_k127_6508287_11 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000175 277.0
HFD2_k127_6508287_12 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000001829 230.0
HFD2_k127_6508287_13 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000002284 219.0
HFD2_k127_6508287_14 lipolytic protein G-D-S-L family K01051 - 3.1.1.11 0.00000000000000000000000000000000000000000000000362 194.0
HFD2_k127_6508287_15 - - - - 0.00000000000000000000000000006619 136.0
HFD2_k127_6508287_16 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000956 118.0
HFD2_k127_6508287_17 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family - - - 0.0001546 54.0
HFD2_k127_6508287_2 response regulator - - - 3.75e-260 838.0
HFD2_k127_6508287_3 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009525 481.0
HFD2_k127_6508287_4 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179 - 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007033 457.0
HFD2_k127_6508287_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 403.0
HFD2_k127_6508287_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003974 302.0
HFD2_k127_6508287_7 Pectic acid lyase K01051 - 3.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005086 308.0
HFD2_k127_6508287_8 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005787 289.0
HFD2_k127_6508287_9 epimerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007527 288.0
HFD2_k127_6511794_0 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005021 374.0
HFD2_k127_6511794_1 nitrite transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001264 275.0
HFD2_k127_6528708_0 PFAM peptidase S9A prolyl oligopeptidase domain protein beta-propeller K01354 - 3.4.21.83 5.457e-251 792.0
HFD2_k127_6528708_1 Aldehyde dehydrogenase family K02618,K15514 - 1.2.1.77,1.2.1.91,3.3.2.12 7.451e-201 637.0
HFD2_k127_6528708_2 Arginase family K01476,K01480 - 3.5.3.1,3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 390.0
HFD2_k127_6528708_4 Acid phosphatase homologues - - - 0.0000000000000003361 89.0
HFD2_k127_6528708_5 Alpha/beta hydrolase of unknown function (DUF1057) - - - 0.0000001273 59.0
HFD2_k127_6528708_6 - - - - 0.0001577 50.0
HFD2_k127_6566232_0 Aminotransferase class-V K01556 - 3.7.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004719 473.0
HFD2_k127_6566232_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 384.0
HFD2_k127_6566232_2 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0008654,GO:0008759,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001003 285.0
HFD2_k127_6566232_3 RNA polymerase sigma factor K03088 - - 0.0000000000000000000000000000000000000000002038 166.0
HFD2_k127_6566232_4 S1 P1 Nuclease - - - 0.0000000000000000000003155 106.0
HFD2_k127_6566232_5 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000003484 56.0
HFD2_k127_6566232_6 Protein of unknown function (DUF1573) - - - 0.0000005094 59.0
HFD2_k127_6583933_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 4.374e-256 820.0
HFD2_k127_6583933_1 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 475.0
HFD2_k127_6583933_2 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009975,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:1901360 6.5.1.4 0.00000000000000000000000000000000000000000000000000001768 198.0
HFD2_k127_6583933_3 Zn peptidase - - - 0.0000000000000000000000000000000000000000000000002033 196.0
HFD2_k127_6583933_4 Transglycosylase SLT domain K08309 - - 0.00000000000000000000000000000000000000002821 164.0
HFD2_k127_6583933_5 - - - - 0.000000000000000000000000006265 115.0
HFD2_k127_6583933_6 Domain of unknown function (DUF4870) - - - 0.000000001215 65.0
HFD2_k127_6583933_7 regulation of DNA repair K03565 GO:0003674,GO:0005575,GO:0005623,GO:0005886,GO:0006282,GO:0008150,GO:0016020,GO:0019219,GO:0019222,GO:0030234,GO:0031323,GO:0044464,GO:0048583,GO:0050789,GO:0050790,GO:0050794,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0080134,GO:0080135,GO:0098772,GO:2001020 - 0.0000001537 64.0
HFD2_k127_6583933_8 Tetratricopeptide repeat - - - 0.000004223 59.0
HFD2_k127_6598098_0 Peptidase M64 N-terminus - - - 1.659e-222 700.0
HFD2_k127_6598098_1 amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 317.0
HFD2_k127_6598098_2 Oxygenase, catalysing oxidative methylation of damaged DNA K09990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008338 296.0
HFD2_k127_6598098_3 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000747 234.0
HFD2_k127_6598098_4 PFAM Hemolysin-type calcium-binding repeat (2 copies) - - - 0.0000000000000000000000000000000000000000000000000000000000008026 230.0
HFD2_k127_6598098_5 - - - - 0.0000000000000000000000000000000000000000000000000000004475 207.0
HFD2_k127_6598098_6 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000001422 186.0
HFD2_k127_6598098_7 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000002504 111.0
HFD2_k127_6598098_8 AhpC/TSA family K03386 - 1.11.1.15 0.0000000000000001124 81.0
HFD2_k127_6598098_9 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000209 65.0
HFD2_k127_6609292_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1062.0
HFD2_k127_6609292_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 441.0
HFD2_k127_6609292_2 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 451.0
HFD2_k127_6609292_3 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007765 378.0
HFD2_k127_6609292_4 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000001083 279.0
HFD2_k127_6609292_5 arylsulfatase activity K07014 - - 0.000000000000000000000000000000000001125 156.0
HFD2_k127_6609292_6 PFAM Ribose galactose isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000001944 154.0
HFD2_k127_6609292_7 Permease for cytosine/purines, uracil, thiamine, allantoin - - - 0.000000000000000016 95.0
HFD2_k127_6629127_0 3'-5' exonuclease K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000001961 207.0
HFD2_k127_6629127_1 acyl-CoA dehydrogenase K09456 - - 0.00000000000000000000000000000004571 136.0
HFD2_k127_6629127_2 lipolytic protein G-D-S-L family K20306 - - 0.0000000000000000001028 103.0
HFD2_k127_6629127_3 COG1226 Kef-type K transport systems - - - 0.000000147 64.0
HFD2_k127_6639577_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K20447 - 1.17.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000395 576.0
HFD2_k127_6639577_1 PA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 403.0
HFD2_k127_6664688_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1362.0
HFD2_k127_6664688_1 Fibronectin type III-like domain K05349 - 3.2.1.21 0.0 1037.0
HFD2_k127_6664688_10 AcrB/AcrD/AcrF family K03296 - - 0.0000000000000000000000000000000000000000005742 179.0
HFD2_k127_6664688_11 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000001991 170.0
HFD2_k127_6664688_12 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.000000000000000000000000000000000514 135.0
HFD2_k127_6664688_13 polysaccharide catabolic process K05991 - 3.2.1.123 0.0000000000000000000000000005326 132.0
HFD2_k127_6664688_14 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000001985 82.0
HFD2_k127_6664688_15 heme iron utilization protein K07226 - - 0.00000000003912 70.0
HFD2_k127_6664688_16 Peptidase M56 - - - 0.000000998 58.0
HFD2_k127_6664688_17 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000002591 56.0
HFD2_k127_6664688_18 von Willebrand factor (vWF) type A domain K07114 - - 0.000006539 60.0
HFD2_k127_6664688_19 Carboxypeptidase regulatory-like domain - - - 0.00003248 55.0
HFD2_k127_6664688_2 Belongs to the glycosyl hydrolase 31 family K01811 - 3.2.1.177 2.069e-271 866.0
HFD2_k127_6664688_20 Tetratricopeptide repeat - - - 0.00004309 55.0
HFD2_k127_6664688_21 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. - - - 0.000958 45.0
HFD2_k127_6664688_3 CBD_II K01179 - 3.2.1.4 1.141e-211 701.0
HFD2_k127_6664688_4 PFAM Xylose isomerase domain protein TIM barrel K01805 - 5.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006916 570.0
HFD2_k127_6664688_5 xylulose kinase K00854 - 2.7.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006908 552.0
HFD2_k127_6664688_6 NAD(P) transhydrogenase beta subunit K00325 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 521.0
HFD2_k127_6664688_7 Converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 404.0
HFD2_k127_6664688_8 HlyD family secretion protein K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 334.0
HFD2_k127_6664688_9 PFAM Bacterial regulatory proteins, lacI family K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002003 263.0
HFD2_k127_6669982_0 ABC transporter ATPase permease K06147 - - 6.696e-270 842.0
HFD2_k127_6669982_1 COG1132 ABC-type multidrug transport system, ATPase and permease components K06147 - - 4.708e-249 786.0
HFD2_k127_6669982_2 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009698 537.0
HFD2_k127_6669982_3 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006685 431.0
HFD2_k127_6669982_4 Asp/Glu/Hydantoin racemase K01779 - 5.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000007888 267.0
HFD2_k127_6669982_5 Caspase domain - - - 0.00000000000000000000000000000001541 146.0
HFD2_k127_6669982_6 PFAM peptidase S1 and S6, chymotrypsin Hap - - - 0.000000004998 68.0
HFD2_k127_6669982_7 heme binding - - - 0.0000004941 63.0
HFD2_k127_6669982_8 serine-type endopeptidase activity - - - 0.00001683 57.0
HFD2_k127_6670770_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006799 530.0
HFD2_k127_6670770_1 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710,K12450 GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 4.2.1.46,4.2.1.76 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 399.0
HFD2_k127_6670770_10 DinB superfamily - - - 0.00000000000000007894 90.0
HFD2_k127_6670770_11 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000001596 91.0
HFD2_k127_6670770_12 PFAM phosphatidate cytidylyltransferase - - - 0.0001241 54.0
HFD2_k127_6670770_2 Initiation factor 2 subunit family K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 396.0
HFD2_k127_6670770_3 MOFRL family K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004138 372.0
HFD2_k127_6670770_4 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 342.0
HFD2_k127_6670770_5 Polysaccharide biosynthesis protein K15856 - 1.1.1.281 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005435 310.0
HFD2_k127_6670770_6 Molybdenum cofactor synthesis domain protein K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008048 281.0
HFD2_k127_6670770_7 Male sterility protein K15891 - 1.1.1.354 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002564 291.0
HFD2_k127_6670770_8 PFAM Integral membrane protein DUF92 - GO:0005575,GO:0016020 - 0.0000000000000000000000000000000000006455 156.0
HFD2_k127_6670770_9 UbiA prenyltransferase family K04040 - 2.5.1.133,2.5.1.62 0.0000000000000000000000434 116.0
HFD2_k127_6701560_0 Forkhead associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000005358 241.0
HFD2_k127_6701560_1 phosphatidylinositol metabolic process K00728 - 2.4.1.109 0.0000000000000000000000000000000000000000000000000000001568 222.0
HFD2_k127_6701560_2 TIGRFAM glutaredoxin-like domain protein - - - 0.0000000000000000000000000001866 122.0
HFD2_k127_6701560_3 alkyl hydroperoxide reductase activity - - - 0.0000000000007549 70.0
HFD2_k127_6710084_0 2-oxoglutarate dehydrogenase, E1 K00164 - 1.2.4.2 0.0 1243.0
HFD2_k127_6710084_1 lysine biosynthetic process via aminoadipic acid - - - 9.881e-224 727.0
HFD2_k127_6710084_10 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001395 282.0
HFD2_k127_6710084_11 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000598 258.0
HFD2_k127_6710084_12 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000003363 242.0
HFD2_k127_6710084_13 PFAM oxidoreductase, molybdopterin binding - - - 0.000000000000000000000000000000000000000000000000000000000000000002427 235.0
HFD2_k127_6710084_14 WHG domain - - - 0.000000000000000000000000000000000000000000002518 171.0
HFD2_k127_6710084_15 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.000000000000000000000000000000000000000000009161 170.0
HFD2_k127_6710084_16 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000008168 156.0
HFD2_k127_6710084_17 Catalyzes the formation of N-acetyl-L-glutamate from acetyl-CoA and L-glutamate K00619 - 2.3.1.1 0.000000000000000000000000000005216 134.0
HFD2_k127_6710084_18 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000000000004718 112.0
HFD2_k127_6710084_19 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000001455 93.0
HFD2_k127_6710084_2 Belongs to the argininosuccinate synthase family. Type K01940 - 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 542.0
HFD2_k127_6710084_20 PKD domain - - - 0.0000000001337 75.0
HFD2_k127_6710084_21 metallopeptidase activity - - - 0.0002646 50.0
HFD2_k127_6710084_3 His Kinase A (phosphoacceptor) domain K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008506 517.0
HFD2_k127_6710084_4 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 417.0
HFD2_k127_6710084_5 Catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate K00812,K14260 - 2.6.1.1,2.6.1.2,2.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 412.0
HFD2_k127_6710084_6 PFAM fumarate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 382.0
HFD2_k127_6710084_7 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 361.0
HFD2_k127_6710084_8 arylsulfatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007858 351.0
HFD2_k127_6710084_9 Arylsulfotransferase (ASST) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009984 317.0
HFD2_k127_6719408_0 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005808 471.0
HFD2_k127_6719408_1 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009477 359.0
HFD2_k127_6719408_10 GAF domain - - - 0.00000000000000000000000000008609 130.0
HFD2_k127_6719408_11 TIGRFAM glutaredoxin-like domain protein - - - 0.000000000000000000000000001218 121.0
HFD2_k127_6719408_12 Membrane - - - 0.000000000000000004783 96.0
HFD2_k127_6719408_13 alkyl hydroperoxide reductase activity - - - 0.00000000000002869 74.0
HFD2_k127_6719408_2 transport system involved in gliding motility, auxiliary K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002317 298.0
HFD2_k127_6719408_3 chromosome segregation K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004267 270.0
HFD2_k127_6719408_4 GTP binding K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001237 275.0
HFD2_k127_6719408_5 Forkhead associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002375 248.0
HFD2_k127_6719408_6 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000001633 231.0
HFD2_k127_6719408_7 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000001117 212.0
HFD2_k127_6719408_8 phosphatidylinositol metabolic process K00728 - 2.4.1.109 0.00000000000000000000000000000000000000000000000000008962 206.0
HFD2_k127_6719408_9 Domain of unknown function (DUF4340) - - - 0.000000000000000000000000000003094 137.0
HFD2_k127_6734317_0 Sortilin, neurotensin receptor 3, - - - 0.0 1277.0
HFD2_k127_6734317_1 Angiotensin-converting enzyme K01283 - 3.4.15.1 2.03e-263 823.0
HFD2_k127_6734317_10 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000000000000001349 215.0
HFD2_k127_6734317_11 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000001966 196.0
HFD2_k127_6734317_12 GTP cyclohydrolase I K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000003847 192.0
HFD2_k127_6734317_13 AraC-like ligand binding domain - - - 0.000000000000000000000000000008438 127.0
HFD2_k127_6734317_14 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000003268 121.0
HFD2_k127_6734317_15 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000333 129.0
HFD2_k127_6734317_16 Putative MetA-pathway of phenol degradation - - - 0.000000004645 67.0
HFD2_k127_6734317_2 ABC transporter, transmembrane K11085 - - 7.964e-209 666.0
HFD2_k127_6734317_3 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 534.0
HFD2_k127_6734317_4 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000057 446.0
HFD2_k127_6734317_5 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003677 436.0
HFD2_k127_6734317_6 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004582 357.0
HFD2_k127_6734317_7 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 320.0
HFD2_k127_6734317_8 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 316.0
HFD2_k127_6734317_9 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002567 273.0
HFD2_k127_6740277_0 Molybdopterin oxidoreductase K07812,K08352 - 1.7.2.3,1.8.5.5 0.0 1286.0
HFD2_k127_6740277_1 Pyridine nucleotide-disulphide oxidoreductase K05297 - 1.18.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006055 581.0
HFD2_k127_6740277_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 462.0
HFD2_k127_6740277_3 GHKL domain - - - 0.00000000000000000000000000000000000000000003561 180.0
HFD2_k127_6740277_4 Bacterial membrane protein, YfhO - - - 0.000000000000000000000000007019 130.0
HFD2_k127_6740277_7 cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.0000004439 56.0
HFD2_k127_6740730_0 synthase K01654 - 2.5.1.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004314 305.0
HFD2_k127_6740730_1 NeuB family K01654,K18430 - 2.5.1.101,2.5.1.56 0.000000000000000000000000000000000000000000001445 177.0
HFD2_k127_6740730_2 Cytidylyltransferase K07257 - - 0.00000000000000000000000000000000000000000008777 180.0
HFD2_k127_6740730_3 - - - - 0.00000001076 68.0
HFD2_k127_6740730_4 PFAM cytidylyltransferase - - - 0.00004461 47.0
HFD2_k127_6741172_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616,K13810 - 2.2.1.2,5.3.1.9 0.0 1184.0
HFD2_k127_6741172_1 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 1.387e-260 812.0
HFD2_k127_6741172_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 600.0
HFD2_k127_6741172_3 6-phosphogluconate dehydrogenase (decarboxylating) K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006669 492.0
HFD2_k127_6741172_4 ROK family K00886 - 2.7.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001392 278.0
HFD2_k127_6741172_5 Phosphoglycerate mutase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003595 283.0
HFD2_k127_6741172_6 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000001258 212.0
HFD2_k127_6783037_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 8.699e-273 848.0
HFD2_k127_6783037_1 Associated with various cellular activities K03924 - - 1.149e-271 842.0
HFD2_k127_6783037_10 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 340.0
HFD2_k127_6783037_11 Domain of unknown function (DUF4162) K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 327.0
HFD2_k127_6783037_12 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008525 332.0
HFD2_k127_6783037_13 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000393 335.0
HFD2_k127_6783037_14 Dihydrodipicolinate reductase, N-terminus K21672 - 1.4.1.12,1.4.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009716 312.0
HFD2_k127_6783037_15 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 304.0
HFD2_k127_6783037_16 Predicted membrane protein (DUF2238) K08984 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001149 281.0
HFD2_k127_6783037_17 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002424 301.0
HFD2_k127_6783037_18 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001217 282.0
HFD2_k127_6783037_19 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.000000000000000000000000000000000000000000000000000000000000000000000000001128 269.0
HFD2_k127_6783037_2 oxidoreductase activity - - - 3.975e-234 754.0
HFD2_k127_6783037_20 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000001477 260.0
HFD2_k127_6783037_21 peptidoglycan glycosyltransferase activity K03588,K05364,K05837 GO:0002682,GO:0002684,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136 - 0.000000000000000000000000000000000000000000000000000000000000000001181 261.0
HFD2_k127_6783037_22 - - - - 0.00000000000000000000000000000000000000000000000000000004695 208.0
HFD2_k127_6783037_23 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000005647 203.0
HFD2_k127_6783037_24 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000008027 188.0
HFD2_k127_6783037_25 TIGRFAM VWFA-related Acidobacterial domain - - - 0.00000000000000000000000000000000000000000278 177.0
HFD2_k127_6783037_26 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000006611 169.0
HFD2_k127_6783037_27 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000000000000000239 140.0
HFD2_k127_6783037_28 - - - - 0.00000000000000000000000000000000004638 150.0
HFD2_k127_6783037_29 Protein of unknown function (DUF1572) - - - 0.0000000000000000000000000001737 121.0
HFD2_k127_6783037_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K03918 - 2.6.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 501.0
HFD2_k127_6783037_30 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.000000000000000000000000001256 123.0
HFD2_k127_6783037_31 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000004726 112.0
HFD2_k127_6783037_32 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00363,K05710 - 1.7.1.15 0.0000000000000000000000008046 107.0
HFD2_k127_6783037_33 Preprotein translocase SecG subunit K03075 - - 0.0000000000000000000009341 99.0
HFD2_k127_6783037_34 - - - - 0.0000000000000002663 87.0
HFD2_k127_6783037_35 Crp Fnr family transcriptional regulator K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.00000000000001075 85.0
HFD2_k127_6783037_36 oxidation-reduction process K09022 - 3.5.99.10 0.000000000000614 72.0
HFD2_k127_6783037_37 Tfp pilus assembly protein FimV - - - 0.00000000005646 75.0
HFD2_k127_6783037_38 Protein conserved in bacteria K09986 - - 0.00000001923 62.0
HFD2_k127_6783037_39 von Willebrand factor, type A K07114 - - 0.0000002274 63.0
HFD2_k127_6783037_4 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 483.0
HFD2_k127_6783037_40 PFAM Type IV pilus assembly PilZ - - - 0.00001259 55.0
HFD2_k127_6783037_41 Redoxin - - - 0.00002998 56.0
HFD2_k127_6783037_42 Mo-molybdopterin cofactor metabolic process K03753,K07588 - - 0.00004375 56.0
HFD2_k127_6783037_5 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 471.0
HFD2_k127_6783037_6 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 462.0
HFD2_k127_6783037_7 TonB dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005659 406.0
HFD2_k127_6783037_8 Natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 398.0
HFD2_k127_6783037_9 alpha/beta hydrolase fold K22318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003641 367.0
HFD2_k127_6792901_0 Sortilin, neurotensin receptor 3, - - - 0.0 1169.0
HFD2_k127_6792901_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004388 484.0
HFD2_k127_6792901_10 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000003227 194.0
HFD2_k127_6792901_11 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008955,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0042546,GO:0043164,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.129 0.00000000000000000000000000000000000000000000000004096 193.0
HFD2_k127_6792901_12 DinB superfamily K07552 - - 0.0000000000000000000000000000000000000005636 155.0
HFD2_k127_6792901_13 Glyoxalase-like domain K05606 GO:0003674,GO:0003824,GO:0004493,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016853,GO:0016854,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046491,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 5.1.99.1 0.00000000000000000000000000000000000002637 150.0
HFD2_k127_6792901_14 PFAM CBS domain K04767 - - 0.0000000000000000000000002527 111.0
HFD2_k127_6792901_15 Protein of unknown function (DUF3105) - - - 0.0000000000000000000003342 108.0
HFD2_k127_6792901_17 ubiE/COQ5 methyltransferase family - - - 0.000000000003067 79.0
HFD2_k127_6792901_18 Protein of unknown function (DUF2752) - - - 0.0000000003288 66.0
HFD2_k127_6792901_2 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004797 353.0
HFD2_k127_6792901_3 FAD dependent oxidoreductase K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007107 319.0
HFD2_k127_6792901_4 ArgK protein K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009033 298.0
HFD2_k127_6792901_5 Belongs to the peptidase S51 family K05995 GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 3.4.13.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000003506 264.0
HFD2_k127_6792901_6 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007133 264.0
HFD2_k127_6792901_7 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000002072 249.0
HFD2_k127_6792901_8 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000001832 231.0
HFD2_k127_6792901_9 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000002229 212.0
HFD2_k127_6817949_0 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain K01596,K01610 - 4.1.1.32,4.1.1.49 1.583e-272 851.0
HFD2_k127_6817949_1 PFAM carboxyl transferase K01969,K15052 - 2.1.3.15,6.4.1.3,6.4.1.4 4.814e-248 783.0
HFD2_k127_6817949_10 Gas vesicle synthesis protein GvpL/GvpF - - - 0.000000000000000000000003305 113.0
HFD2_k127_6817949_11 Domain of unknown function (DUF4956) - - - 0.000000000000000000001159 107.0
HFD2_k127_6817949_12 Gas vesicle protein K - - - 0.000000000000000000002545 107.0
HFD2_k127_6817949_13 Biotin carboxylase C-terminal domain K01968 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.4.1.4 0.000000000000000000007749 103.0
HFD2_k127_6817949_14 Tetratricopeptide repeat - - - 0.000000000001136 81.0
HFD2_k127_6817949_15 gibberellic acid mediated signaling pathway - GO:0001101,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0007154,GO:0007165,GO:0008150,GO:0008194,GO:0008375,GO:0009719,GO:0009725,GO:0009735,GO:0009736,GO:0009739,GO:0009740,GO:0009755,GO:0009937,GO:0009938,GO:0009966,GO:0009968,GO:0009987,GO:0010033,GO:0010476,GO:0010646,GO:0010648,GO:0016262,GO:0016740,GO:0016757,GO:0016758,GO:0019222,GO:0023051,GO:0023052,GO:0023057,GO:0031323,GO:0032870,GO:0033993,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071229,GO:0071310,GO:0071368,GO:0071370,GO:0071396,GO:0071495,GO:0140096,GO:1901700,GO:1901701,GO:2000377 - 0.0000000001849 74.0
HFD2_k127_6817949_16 Tetratricopeptide repeat - - - 0.0000003578 62.0
HFD2_k127_6817949_17 Gas vesicle protein - - - 0.000003167 59.0
HFD2_k127_6817949_2 CoA carboxylase activity K01968 - 6.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 542.0
HFD2_k127_6817949_3 COG0119 Isopropylmalate homocitrate citramalate synthases K01640 - 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 349.0
HFD2_k127_6817949_4 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000242 347.0
HFD2_k127_6817949_5 PFAM Enoyl-CoA hydratase isomerase K13766,K15312 - 4.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000003004 246.0
HFD2_k127_6817949_6 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000001232 250.0
HFD2_k127_6817949_7 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000003408 203.0
HFD2_k127_6817949_8 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000000000001412 170.0
HFD2_k127_6817949_9 cheY-homologous receiver domain - - - 0.0000000000000000000000004124 114.0
HFD2_k127_6828257_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 7.437e-213 675.0
HFD2_k127_6828257_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 8.936e-201 649.0
HFD2_k127_6828257_2 Protein of unknown function DUF86 - - - 0.000000000003551 76.0
HFD2_k127_693288_0 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 4.622e-216 685.0
HFD2_k127_693288_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 507.0
HFD2_k127_693288_10 Methyltransferase K08316 - 2.1.1.171 0.00000000000000000000000000000000002836 143.0
HFD2_k127_693288_11 ribonuclease activity - - - 0.000000000000000000000000002357 119.0
HFD2_k127_693288_12 - - - - 0.0000000000002383 83.0
HFD2_k127_693288_13 Bacterial antitoxin of type II TA system, VapB - - - 0.0000000000007206 70.0
HFD2_k127_693288_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 436.0
HFD2_k127_693288_3 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 387.0
HFD2_k127_693288_4 Aminotransferase, class V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 358.0
HFD2_k127_693288_5 Aminotransferase K00812,K22457 GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297 2.6.1.1,2.6.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004091 319.0
HFD2_k127_693288_6 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000003651 244.0
HFD2_k127_693288_7 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.000000000000000000000000000000000000000000000000000001664 207.0
HFD2_k127_693288_8 ECF sigma factor - - - 0.000000000000000000000000000000000000000000001974 171.0
HFD2_k127_693288_9 GAF domain - - - 0.000000000000000000000000000000000006501 149.0
HFD2_k127_7056106_0 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000001792 267.0
HFD2_k127_7056106_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000004079 235.0
HFD2_k127_7056106_2 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 0.000000000000000000000000000000000000000000000000000001505 198.0
HFD2_k127_7056106_3 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000004244 161.0
HFD2_k127_7078354_0 NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004685 316.0
HFD2_k127_7078354_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000003373 190.0
HFD2_k127_7078354_2 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00000000001849 72.0
HFD2_k127_7082983_0 Response regulator receiver - - - 2.658e-200 635.0
HFD2_k127_7082983_1 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008641 604.0
HFD2_k127_7082983_10 PFAM ABC transporter K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000001371 211.0
HFD2_k127_7082983_11 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000000000004208 226.0
HFD2_k127_7082983_12 Metallo-peptidase family M12 - - - 0.0000000000000000000000000000000005517 153.0
HFD2_k127_7082983_2 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004507 565.0
HFD2_k127_7082983_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 465.0
HFD2_k127_7082983_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 406.0
HFD2_k127_7082983_5 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 367.0
HFD2_k127_7082983_6 transport, permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 317.0
HFD2_k127_7082983_7 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007865 316.0
HFD2_k127_7082983_8 Transport permease protein K01992 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0015562,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0033554,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000409 324.0
HFD2_k127_7082983_9 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001551 275.0
HFD2_k127_7103501_0 iron-sulfur binding K00184 - - 1.133e-289 919.0
HFD2_k127_7103501_1 cellulose binding - - - 7.685e-261 836.0
HFD2_k127_7103501_10 cytochrome c - - - 0.000000000000000000000000000000000000000000008217 176.0
HFD2_k127_7103501_11 HIT domain K02503 - - 0.00000000000000000000000000000000000000004227 154.0
HFD2_k127_7103501_12 Protein of unknown function (DUF3341) - - - 0.000000000000000000000000000000000001016 147.0
HFD2_k127_7103501_13 - - - - 0.00000000000000000000000002867 114.0
HFD2_k127_7103501_14 Ribosomal protein L31 K02909 - - 0.0000000000000000000003926 104.0
HFD2_k127_7103501_15 Cytochrome c554 and c-prime - - - 0.00000000000000000002669 108.0
HFD2_k127_7103501_16 Protein conserved in bacteria - - - 0.00000000000001656 87.0
HFD2_k127_7103501_17 GAF domain - - - 0.0000000000001596 78.0
HFD2_k127_7103501_2 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 649.0
HFD2_k127_7103501_3 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 490.0
HFD2_k127_7103501_4 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009534 476.0
HFD2_k127_7103501_5 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01665 GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046820,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006967 299.0
HFD2_k127_7103501_6 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001008 296.0
HFD2_k127_7103501_7 A G-specific K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000897 286.0
HFD2_k127_7103501_8 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000002459 261.0
HFD2_k127_7103501_9 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000000008737 209.0
HFD2_k127_7116550_0 Dynamin family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 512.0
HFD2_k127_7116550_1 Citrate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004332 398.0
HFD2_k127_7116550_2 PFAM WD40 domain protein beta Propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 325.0
HFD2_k127_7116550_3 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000004996 175.0
HFD2_k127_7116550_4 ABC-type amino acid transport signal transduction systems periplasmic component domain - - - 0.0000000000000000002696 104.0
HFD2_k127_7119529_0 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000001573 126.0
HFD2_k127_7119529_1 D-alanine [D-alanyl carrier protein] ligase activity K16428,K16429 - - 0.00001237 58.0
HFD2_k127_7120184_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000039 365.0
HFD2_k127_7120184_1 Heat shock 70 kDa protein K04045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 326.0
HFD2_k127_7120184_2 FHA domain - - - 0.000000000002678 80.0
HFD2_k127_7120184_3 zinc metalloprotease K11749 - - 0.0003892 52.0
HFD2_k127_7120184_4 zinc metalloprotease K11749 GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016021,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0043170,GO:0043856,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045152,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:0140110,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.000467 52.0
HFD2_k127_7181544_0 Glycogen debranching enzyme N terminal - - - 2.334e-268 872.0
HFD2_k127_7181544_1 Domain of unknown function (DUF3459) K01236 - 3.2.1.141 6.161e-241 761.0
HFD2_k127_7181544_10 Acetamidase formamidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 297.0
HFD2_k127_7181544_11 CHASE3 domain K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 313.0
HFD2_k127_7181544_12 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004054 296.0
HFD2_k127_7181544_13 PAS domain containing protein K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001512 268.0
HFD2_k127_7181544_14 BMC - - - 0.0000000000000000000000000000000000000000000000000000000000000000004084 240.0
HFD2_k127_7181544_15 Transcriptional regulatory protein, C terminal K07658 - - 0.000000000000000000000000000000000000000000000000000005741 218.0
HFD2_k127_7181544_16 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000201 165.0
HFD2_k127_7181544_17 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896 3.5.1.44 0.00000000000000000000000000000000006574 153.0
HFD2_k127_7181544_18 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000003607 148.0
HFD2_k127_7181544_19 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000006671 142.0
HFD2_k127_7181544_2 Chemotaxis protein histidine kinase and related kinases K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 505.0
HFD2_k127_7181544_20 chemotaxis signal transduction protein K03408 - - 0.0000000000000000000000000000005476 141.0
HFD2_k127_7181544_21 phosphate ion binding - - - 0.000000000000000000000000000003016 124.0
HFD2_k127_7181544_22 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain - - - 0.00000000000000000000000000005613 134.0
HFD2_k127_7181544_23 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain K15012 - - 0.00001807 54.0
HFD2_k127_7181544_24 chemotaxis K02659,K03408 - - 0.00005502 55.0
HFD2_k127_7181544_3 Bacterial regulatory protein, Fis family K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005312 489.0
HFD2_k127_7181544_4 LytB protein K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 449.0
HFD2_k127_7181544_5 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000878 400.0
HFD2_k127_7181544_6 histidine kinase HAMP region domain protein K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 342.0
HFD2_k127_7181544_7 TonB dependent receptor K16087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 336.0
HFD2_k127_7181544_8 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 319.0
HFD2_k127_7181544_9 Enoyl- acyl-carrier-protein reductase NADH K00208 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006950,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0033554,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051716,GO:0055114,GO:0065003,GO:0070417,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 302.0
HFD2_k127_7202176_0 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 353.0
HFD2_k127_7202176_1 cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 312.0
HFD2_k127_7202176_2 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000001242 144.0
HFD2_k127_7297198_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009643 485.0
HFD2_k127_7297198_1 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 437.0
HFD2_k127_7297198_10 - - - - 0.000000000000000000000000000000000000000000009262 177.0
HFD2_k127_7297198_11 Predicted permease K07089 - - 0.0000000000000000000000000001308 118.0
HFD2_k127_7297198_12 PFAM YbaK prolyl-tRNA synthetase associated region K19055 - - 0.000000000000000000000000001136 124.0
HFD2_k127_7297198_13 PFAM Uncharacterised BCR, COG1649 - - - 0.0000000000000000000000002979 124.0
HFD2_k127_7297198_14 RDD family - - - 0.00000000000000000007725 104.0
HFD2_k127_7297198_15 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.0000000000000001317 85.0
HFD2_k127_7297198_16 Ribonuclease H-like K09776 - - 0.0000000000000003895 85.0
HFD2_k127_7297198_17 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase - - - 0.00000000003763 74.0
HFD2_k127_7297198_18 Serine aminopeptidase, S33 K06889 - - 0.00007285 51.0
HFD2_k127_7297198_2 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004165 374.0
HFD2_k127_7297198_3 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008788 346.0
HFD2_k127_7297198_4 Mediates influx of magnesium ions K03284,K16074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 308.0
HFD2_k127_7297198_5 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000111 255.0
HFD2_k127_7297198_6 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000005493 246.0
HFD2_k127_7297198_7 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000000000000001217 200.0
HFD2_k127_7297198_9 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000602 180.0
HFD2_k127_7326697_0 peptidase K07386 - - 2.774e-300 934.0
HFD2_k127_7326697_1 Leukotriene A4 hydrolase, C-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007093 617.0
HFD2_k127_7326697_2 RecA-superfamily ATPases implicated in signal transduction K08482 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 582.0
HFD2_k127_7326697_3 peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 492.0
HFD2_k127_7326697_4 Histidine kinase K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 426.0
HFD2_k127_7326697_5 NAD(P)H-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004873 280.0
HFD2_k127_7326697_6 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000046 199.0
HFD2_k127_7326697_7 response to cobalt ion - - - 0.000000000000000000005066 102.0
HFD2_k127_7326697_8 CAAX protease self-immunity K07052 - - 0.0005405 52.0
HFD2_k127_7354570_0 GTP-binding protein TypA K06207 - - 1.992e-271 849.0
HFD2_k127_7354570_1 Penicillin amidase K01434,K07116 - 3.5.1.11,3.5.1.97 5.018e-202 652.0
HFD2_k127_7354570_10 Glucose / Sorbosone dehydrogenase - - - 0.00000002936 67.0
HFD2_k127_7354570_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388,K12527 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6,1.97.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006053 531.0
HFD2_k127_7354570_3 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006055 432.0
HFD2_k127_7354570_4 Winged helix DNA-binding domain K09927 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007371 371.0
HFD2_k127_7354570_5 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001637 281.0
HFD2_k127_7354570_6 Tetratricopeptide repeat - - - 0.0000000000000000000000000001317 122.0
HFD2_k127_7354570_7 TPM domain K06872 - - 0.0000000000000000000000000001748 130.0
HFD2_k127_7354570_8 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.00000000000000000000000000216 130.0
HFD2_k127_7354570_9 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000005419 100.0
HFD2_k127_7364343_0 PFAM Prolyl oligopeptidase family - - - 5.424e-276 862.0
HFD2_k127_7364343_1 ATP dependent DNA ligase C terminal region K01971 - 6.5.1.1 1.698e-265 848.0
HFD2_k127_7364343_10 Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily K01488 GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.4 0.0000000000000000000000000000000000000000000002142 180.0
HFD2_k127_7364343_11 YhhN family - - - 0.00000000000000000000000004131 124.0
HFD2_k127_7364343_12 Alpha beta hydrolase - - - 0.000000000000005082 76.0
HFD2_k127_7364343_13 Domain of unknown function (DUF4386) - - - 0.00000000000001825 84.0
HFD2_k127_7364343_2 DNA polymerase beta thumb K02347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004299 539.0
HFD2_k127_7364343_3 PFAM peptidase M24 K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 400.0
HFD2_k127_7364343_4 PFAM Aldo keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 392.0
HFD2_k127_7364343_5 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000001014 265.0
HFD2_k127_7364343_6 dna ligase K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000002998 265.0
HFD2_k127_7364343_7 Inhibitor of apoptosis-promoting Bax1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004757 286.0
HFD2_k127_7364343_8 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007471 266.0
HFD2_k127_7364343_9 - - - - 0.00000000000000000000000000000000000000000000000003392 203.0
HFD2_k127_7365893_0 3'-5' exonuclease K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000001372 226.0
HFD2_k127_7365893_1 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000001714 195.0
HFD2_k127_7365893_2 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.00001784 57.0
HFD2_k127_7379318_0 Belongs to the glycosyl hydrolase 31 family K01187 - 3.2.1.20 1.234e-222 724.0
HFD2_k127_7379318_1 4-alpha-glucanotransferase K00705 - 2.4.1.25 8.779e-200 637.0
HFD2_k127_7379318_10 Metallo-peptidase family M12 - - - 0.00000000000000000000000000001173 137.0
HFD2_k127_7379318_11 Iron-binding zinc finger CDGSH type K05710 - - 0.0000000000000000000000002328 107.0
HFD2_k127_7379318_2 MFS/sugar transport protein K16211 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 524.0
HFD2_k127_7379318_3 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 414.0
HFD2_k127_7379318_4 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008663 302.0
HFD2_k127_7379318_5 Ferritin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007171 271.0
HFD2_k127_7379318_6 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008668 254.0
HFD2_k127_7379318_7 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000000127 179.0
HFD2_k127_7379318_8 Belongs to the GcvT family K06980 - - 0.000000000000000000000000000000008993 141.0
HFD2_k127_7379318_9 Cyclomaltodextrinase, N-terminal K21575 - 3.2.1.135 0.0000000000000000000000000000001031 139.0
HFD2_k127_7399337_0 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000004398 161.0
HFD2_k127_7399337_1 Gas vesicle protein K - - - 0.0000000000000000000001868 102.0
HFD2_k127_7399337_2 Domain of unknown function (DUF4956) - - - 0.00000000000000000003345 103.0
HFD2_k127_7419213_0 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 1.678e-195 624.0
HFD2_k127_7419213_1 PFAM Phosphoribosyl transferase domain K07100 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001062 268.0
HFD2_k127_7419213_2 carboxymethylenebutenolidase activity K01061,K07100 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000001377 278.0
HFD2_k127_7419213_3 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000005323 217.0
HFD2_k127_7419213_4 type II secretion system K02454 - - 0.00000000000000000000000000000000000000000000001904 175.0
HFD2_k127_7419213_5 AMMECR1 K09141 - - 0.000000000000000000000000000000000000001336 164.0
HFD2_k127_7419213_6 Lysin motif - - - 0.000000000000000000000000000000000003856 144.0
HFD2_k127_7419213_7 Domain of unknown function (DUF4912) K09942 - - 0.000000000005393 76.0
HFD2_k127_7435907_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 6.668e-205 657.0
HFD2_k127_7435907_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 447.0
HFD2_k127_7435907_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004313 325.0
HFD2_k127_7435907_3 PFAM iron dependent repressor K03709 - - 0.000000000000000000000000000000000000000000000001127 185.0
HFD2_k127_7435907_5 OsmC-like protein - - - 0.000000489 63.0
HFD2_k127_7435907_6 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000004993 55.0
HFD2_k127_7435907_7 FeoA K04758 - - 0.00000847 58.0
HFD2_k127_7492800_0 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007423 269.0
HFD2_k127_7492800_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000002998 250.0
HFD2_k127_7492800_2 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.0000000000000000000000000000000000000000000000000000000000001327 212.0
HFD2_k127_7492800_3 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000007227 146.0
HFD2_k127_7492800_4 - - - - 0.00000004169 56.0
HFD2_k127_7525567_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006345 447.0
HFD2_k127_7525567_1 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 385.0
HFD2_k127_7525567_2 Serine Threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000007844 247.0
HFD2_k127_7525567_3 - - - - 0.0000000000000000000000001026 119.0
HFD2_k127_7525567_4 Bacterioferritin comigratory K03564 - 1.11.1.15 0.000000000003169 68.0
HFD2_k127_7621010_0 Belongs to the enoyl-CoA hydratase isomerase family K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 4.387e-217 712.0
HFD2_k127_7621010_1 Thiolase, C-terminal domain K00632 - 2.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 505.0
HFD2_k127_7621010_2 CoA-transferase family III K01796 - 5.1.99.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003098 312.0
HFD2_k127_7621010_3 acyl-CoA dehydrogenase K09456 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000177 318.0
HFD2_k127_7623166_0 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000000000000000000002162 193.0
HFD2_k127_7623166_1 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000000002657 170.0
HFD2_k127_7623166_2 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0000000000000000000000000000006423 139.0
HFD2_k127_7623166_3 Tetratricopeptide repeat - - - 0.000005633 59.0
HFD2_k127_7632155_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007509 488.0
HFD2_k127_7632155_1 L,D-transpeptidase catalytic domain K21470 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 371.0
HFD2_k127_7632155_2 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004642 318.0
HFD2_k127_7632155_3 Nitroreductase family - - - 0.000000000000000000000000000000000000006196 161.0
HFD2_k127_7632155_4 PFAM Bacterial regulatory protein, arsR family - - - 0.000000000004321 70.0
HFD2_k127_7652585_0 Aconitase C-terminal domain K01703 - 4.2.1.33,4.2.1.35 2.012e-290 904.0
HFD2_k127_7652585_1 Acetyl-coenzyme A transporter 1 K08218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000887 545.0
HFD2_k127_7652585_10 PFAM glycosyl transferase family 39 K14340 - - 0.0000000000000000000000000000001228 144.0
HFD2_k127_7652585_12 CHRD domain - - - 0.0000000000000000000000000000003986 128.0
HFD2_k127_7652585_13 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000009379 141.0
HFD2_k127_7652585_14 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000008431 124.0
HFD2_k127_7652585_15 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000000000001168 125.0
HFD2_k127_7652585_16 GDSL-like Lipase/Acylhydrolase - - - 0.00000000000000000000003011 117.0
HFD2_k127_7652585_17 - - - - 0.0000000000000002659 85.0
HFD2_k127_7652585_18 Methyltransferase domain - - - 0.000000007684 69.0
HFD2_k127_7652585_19 - - - - 0.00000002025 62.0
HFD2_k127_7652585_2 Amino acid kinase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008865 437.0
HFD2_k127_7652585_20 WD40-like Beta Propeller Repeat K03641 - - 0.0000002001 63.0
HFD2_k127_7652585_21 - - - - 0.00000174 51.0
HFD2_k127_7652585_22 AntiSigma factor - - - 0.0003332 53.0
HFD2_k127_7652585_3 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 445.0
HFD2_k127_7652585_4 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 417.0
HFD2_k127_7652585_5 Dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009278 418.0
HFD2_k127_7652585_6 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 382.0
HFD2_k127_7652585_7 SpoIVB peptidase S55 K00973,K02414,K21449 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 362.0
HFD2_k127_7652585_8 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005784 303.0
HFD2_k127_7652585_9 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009296 259.0
HFD2_k127_7657210_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 2.226e-291 911.0
HFD2_k127_7657210_1 DNA topoisomerase VI subunit A K03166 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 606.0
HFD2_k127_7657210_2 phosphopantetheine binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004214 493.0
HFD2_k127_7657210_3 Beta-lactamase class C and other penicillin binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009076 265.0
HFD2_k127_7657210_4 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11 0.00000000000000000000000000000000000000000000000000000000000000001065 232.0
HFD2_k127_7657210_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000001533 248.0
HFD2_k127_7657210_7 viral genome integration into host DNA - - - 0.0000000000000000005476 87.0
HFD2_k127_7657210_8 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000074 76.0
HFD2_k127_7668581_0 homolog of phage Mu protein gp47 - - - 3.902e-241 778.0
HFD2_k127_7668581_1 PFAM AAA ATPase central domain protein - - - 5.599e-219 699.0
HFD2_k127_7668581_10 Rhs element vgr protein - - - 0.0000000000000000000000000000000000000000000000000000000000000002601 241.0
HFD2_k127_7668581_11 cell septum assembly K01990,K03466,K08372 - - 0.0000000000000000000000000000000000000000000000000000001805 224.0
HFD2_k127_7668581_12 cell septum assembly K01990,K03466,K08372 - - 0.00000000000000000000000000000000000000000000000000000341 216.0
HFD2_k127_7668581_13 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000003406 194.0
HFD2_k127_7668581_14 Gene 25-like lysozyme K06903 - - 0.0000000000000000000000000000000000000000003099 162.0
HFD2_k127_7668581_15 Domain of unknown function (DUF4157) - - - 0.0000000000000000000000000000000003149 152.0
HFD2_k127_7668581_16 - - - - 0.00000000000000000000000000000004708 129.0
HFD2_k127_7668581_17 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K02014 - - 0.000000000000000000000000003751 122.0
HFD2_k127_7668581_18 LysM domain - - - 0.00000000000000000000000001248 117.0
HFD2_k127_7668581_19 - - - - 0.0000000000000000000004962 113.0
HFD2_k127_7668581_2 cellular response to nickel ion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 626.0
HFD2_k127_7668581_20 membrane protein (DUF2079) - - - 0.00000000001785 77.0
HFD2_k127_7668581_21 Protein of unknown function (DUF4255) - - - 0.000003363 50.0
HFD2_k127_7668581_22 - - - - 0.0000958 51.0
HFD2_k127_7668581_3 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 565.0
HFD2_k127_7668581_4 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 522.0
HFD2_k127_7668581_5 Alanine dehydrogenase/PNT, N-terminal domain K00324 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 476.0
HFD2_k127_7668581_6 Late control gene D protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 452.0
HFD2_k127_7668581_7 Belongs to the peptidase M16 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 456.0
HFD2_k127_7668581_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000693 282.0
HFD2_k127_7668581_9 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000007004 237.0
HFD2_k127_7712517_0 two-component system sensor protein - - - 0.0 1051.0
HFD2_k127_7712517_1 FAD linked oxidase domain protein K00102 - 1.1.2.4 7.009e-197 623.0
HFD2_k127_7712517_10 YjbR - - - 0.000000000000000000000000000009799 134.0
HFD2_k127_7712517_11 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000005368 70.0
HFD2_k127_7712517_12 - - - - 0.000000002565 64.0
HFD2_k127_7712517_2 PFAM O-methyltransferase family 2 K09846 - 2.1.1.210 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 400.0
HFD2_k127_7712517_3 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004494 346.0
HFD2_k127_7712517_4 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 344.0
HFD2_k127_7712517_5 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 335.0
HFD2_k127_7712517_6 arylsulfatase A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004964 299.0
HFD2_k127_7712517_7 PAC sensor-containing diguanylate cyclase phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000001886 192.0
HFD2_k127_7712517_8 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000005834 173.0
HFD2_k127_7712517_9 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000007752 160.0
HFD2_k127_7796094_0 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 341.0
HFD2_k127_7796094_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002889 320.0
HFD2_k127_7796094_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005126 307.0
HFD2_k127_779650_0 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007592 516.0
HFD2_k127_779650_1 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000000000001374 222.0
HFD2_k127_779650_2 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000002763 158.0
HFD2_k127_779650_3 Metallo-peptidase family M12 - - - 0.00000000000000000000000000001337 137.0
HFD2_k127_779650_4 Penicillin acylase K01434 - 3.5.1.11 0.000000000000000000001028 98.0
HFD2_k127_780982_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 7.964e-273 857.0
HFD2_k127_780982_1 Thiamine pyrophosphate enzyme, central domain K03336 - 3.7.1.22 1.599e-238 770.0
HFD2_k127_780982_2 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004768 441.0
HFD2_k127_780982_3 Fungalysin metallopeptidase (M36) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005844 318.0
HFD2_k127_780982_4 Two component regulator propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002462 289.0
HFD2_k127_780982_5 PFAM Xylose isomerase-like TIM barrel K03335 - 4.2.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000001598 248.0
HFD2_k127_780982_6 response regulator - - - 0.0000000000000000000000000000000000000000004332 170.0
HFD2_k127_780982_7 Oxidoreductase family, NAD-binding Rossmann fold K00010 - 1.1.1.18,1.1.1.369 0.00000000000000000000000000000000000000001944 168.0
HFD2_k127_7825565_0 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008326 347.0
HFD2_k127_7825565_1 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004246 333.0
HFD2_k127_7825565_10 Tetratricopeptide repeat - - - 0.00007402 55.0
HFD2_k127_7825565_2 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001848 287.0
HFD2_k127_7825565_3 TIGRFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005015 270.0
HFD2_k127_7825565_4 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000007943 209.0
HFD2_k127_7825565_5 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000000001227 170.0
HFD2_k127_7825565_6 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000512 139.0
HFD2_k127_7825565_7 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000001406 134.0
HFD2_k127_7825565_8 Radical SAM domain protein - - - 0.000000000000000000000000001991 125.0
HFD2_k127_7825565_9 Tetratricopeptide repeat - - - 0.00000000001114 78.0
HFD2_k127_7835716_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003954 424.0
HFD2_k127_7835716_1 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007989 373.0
HFD2_k127_7835716_2 Formyl transferase K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000002352 220.0
HFD2_k127_7835716_3 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000002711 153.0
HFD2_k127_7835716_4 - - - - 0.00000000002966 64.0
HFD2_k127_7836603_0 Endonuclease Exonuclease Phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005574 509.0
HFD2_k127_7836603_1 Cupin superfamily protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006214 287.0
HFD2_k127_7836603_3 Metallo-peptidase family M12 - - - 0.00000000000000000000000000000000000000006457 173.0
HFD2_k127_7836603_4 negative regulation of transcription, DNA-templated - - - 0.00000000000000000000000000000000799 130.0
HFD2_k127_7836603_5 efflux transmembrane transporter activity - - - 0.000000001067 66.0
HFD2_k127_7836603_6 COG0577 ABC-type antimicrobial peptide transport system permease component - - - 0.00000003053 63.0
HFD2_k127_7836603_7 general secretion pathway protein - - - 0.000003172 49.0
HFD2_k127_7836861_0 Acyl-CoA dehydrogenase, C-terminal domain K00248,K09478 - 1.3.8.1,1.3.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 550.0
HFD2_k127_7836861_1 Saccharopine dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 367.0
HFD2_k127_7836861_2 Acetylornithine aminotransferase K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007595 353.0
HFD2_k127_7836861_3 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003834 305.0
HFD2_k127_7836861_4 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001023 281.0
HFD2_k127_7836861_5 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K07025 - - 0.00000000000000000001075 100.0
HFD2_k127_7836861_6 COG3404 Methenyl tetrahydrofolate cyclohydrolase - - - 0.000002671 60.0
HFD2_k127_7923235_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 3.455e-254 796.0
HFD2_k127_7923235_1 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004064 495.0
HFD2_k127_7923235_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 369.0
HFD2_k127_7923235_3 YmdB-like protein K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002989 280.0
HFD2_k127_7923235_4 Bacterial regulatory proteins, tetR family K16137 - - 0.000000000000000000000000000000000000000000000000000000000000000000004913 241.0
HFD2_k127_7923235_5 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000005965 194.0
HFD2_k127_7923235_6 - - - - 0.00000000000000000000000000000000000000000000000000002293 196.0
HFD2_k127_7923235_7 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000336 198.0
HFD2_k127_7923235_8 PAS fold - - - 0.000000000000000000000000000000000003024 143.0
HFD2_k127_7929695_0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 6.927e-305 960.0
HFD2_k127_7929695_1 ASPIC and UnbV - - - 7.967e-219 701.0
HFD2_k127_7929695_10 Bacterial regulatory protein, Fis family K13599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 349.0
HFD2_k127_7929695_11 Belongs to the binding-protein-dependent transport system permease family K10544 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 327.0
HFD2_k127_7929695_12 NADH dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002121 288.0
HFD2_k127_7929695_13 Tryptophan halogenase K21401 - 1.3.99.38 0.000000000000000000000000000000000000000000000000000000000000000000000000001239 270.0
HFD2_k127_7929695_14 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003525 252.0
HFD2_k127_7929695_15 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000005785 256.0
HFD2_k127_7929695_16 NAD(P)H-dependent FMN reductase K19784 - - 0.000000000000000000000000000000000000000000000001381 187.0
HFD2_k127_7929695_17 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000005432 196.0
HFD2_k127_7929695_18 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000004765 166.0
HFD2_k127_7929695_19 Hydrogenase 4 membrane K12140 - - 0.0000000000000000000000000000000000000002939 158.0
HFD2_k127_7929695_2 ABC transporter K02056,K05776,K10441,K10545,K10548 - 3.6.3.17 1.531e-205 671.0
HFD2_k127_7929695_20 C4-type zinc ribbon domain K07164 - - 0.0000000006816 69.0
HFD2_k127_7929695_21 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.000000738 58.0
HFD2_k127_7929695_22 response regulator - - - 0.0009458 48.0
HFD2_k127_7929695_3 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000388 632.0
HFD2_k127_7929695_4 Cyclomaltodextrinase, N-terminal K21575 - 3.2.1.135 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 536.0
HFD2_k127_7929695_5 Periplasmic binding protein domain K10543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005847 469.0
HFD2_k127_7929695_6 PFAM NADH Ubiquinone plastoquinone (complex I) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009763 490.0
HFD2_k127_7929695_7 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003043 473.0
HFD2_k127_7929695_8 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 485.0
HFD2_k127_7929695_9 plastoquinone (Complex I) K12141 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005899 361.0
HFD2_k127_8009370_0 PFAM NAD-dependent epimerase dehydratase K12454 - 5.1.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 538.0
HFD2_k127_8009370_1 Male sterility protein K12454 - 5.1.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 435.0
HFD2_k127_8009370_2 COG0463 Glycosyltransferases involved in cell wall K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 398.0
HFD2_k127_8009370_3 Protein of unknown function (DUF3224) - - - 0.0000000000000000000000000000000007509 135.0
HFD2_k127_8009370_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000006343 98.0
HFD2_k127_8009370_5 TIGRFAM VWFA-related Acidobacterial domain - - - 0.0000006176 57.0
HFD2_k127_8010261_0 Glycosyl hydrolase family 115 - - - 0.0 1128.0
HFD2_k127_8010261_1 cytochrome C peroxidase - - - 0.0 1039.0
HFD2_k127_8010261_10 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 452.0
HFD2_k127_8010261_11 GDSL-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003368 433.0
HFD2_k127_8010261_12 Aminotransferase class-V K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003911 437.0
HFD2_k127_8010261_13 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 357.0
HFD2_k127_8010261_14 COG3119 Arylsulfatase A K01134 - 3.1.6.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 347.0
HFD2_k127_8010261_15 ROK family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003906 346.0
HFD2_k127_8010261_16 pfam abc K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 328.0
HFD2_k127_8010261_17 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000745 321.0
HFD2_k127_8010261_18 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 304.0
HFD2_k127_8010261_19 amine dehydrogenase activity K14647,K21449 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005551 314.0
HFD2_k127_8010261_2 Carboxypeptidase regulatory-like domain - - - 2.363e-247 803.0
HFD2_k127_8010261_20 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006645 295.0
HFD2_k127_8010261_21 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 288.0
HFD2_k127_8010261_22 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005489 294.0
HFD2_k127_8010261_23 helix_turn_helix, Lux Regulon K07693 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001353 278.0
HFD2_k127_8010261_24 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002288 256.0
HFD2_k127_8010261_25 TIGRFAM RarD protein, DMT superfamily transporter K05786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002926 273.0
HFD2_k127_8010261_26 Fatty acid hydroxylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000001786 232.0
HFD2_k127_8010261_27 Histidine kinase K07778 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000006766 231.0
HFD2_k127_8010261_28 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000004642 229.0
HFD2_k127_8010261_29 PFAM Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000007431 218.0
HFD2_k127_8010261_3 Hydrolase CocE NonD family - - - 3.728e-242 764.0
HFD2_k127_8010261_30 ABC-2 type transporter - - - 0.0000000000000000000000000000000000000000000000000002572 207.0
HFD2_k127_8010261_31 Methyltransferase type 11 K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000005706 192.0
HFD2_k127_8010261_32 Bacterial-like globin K06886 - - 0.0000000000000000000000000000000000000000000000756 173.0
HFD2_k127_8010261_33 PIN domain K07062 - - 0.000000000000000000000000000000000000000000000352 173.0
HFD2_k127_8010261_34 Cytidylyltransferase K18431 - 2.7.7.82 0.0000000000000000000000000000000000000000000959 170.0
HFD2_k127_8010261_35 COG2346, Truncated hemoglobins - - - 0.00000000000000000000000000000000000002748 150.0
HFD2_k127_8010261_36 Yhs domain-containing protein - - - 0.00000000000000000000000000000000000003478 150.0
HFD2_k127_8010261_37 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000001513 149.0
HFD2_k127_8010261_38 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000002436 141.0
HFD2_k127_8010261_39 Metallo-peptidase family M12 - - - 0.000000000000000000000000000000002752 149.0
HFD2_k127_8010261_4 Belongs to the mandelate racemase muconate lactonizing enzyme family K01706 - 4.2.1.40 3.988e-218 681.0
HFD2_k127_8010261_40 - - - - 0.00000000000000000000000000001089 126.0
HFD2_k127_8010261_41 Metallo-peptidase family M12 - - - 0.00000000000000000000000000001149 137.0
HFD2_k127_8010261_42 ASPIC and UnbV - - - 0.000000000000000000000000001086 129.0
HFD2_k127_8010261_43 - - - - 0.000000000000000000000000003218 114.0
HFD2_k127_8010261_44 transcriptional regulator - - - 0.00000000000000000000000001355 113.0
HFD2_k127_8010261_45 Helix-turn-helix domain - - - 0.0000000000000000000000002584 116.0
HFD2_k127_8010261_46 - - - - 0.00000000000000000000002806 108.0
HFD2_k127_8010261_47 Domain of unknown function (DUF4157) - - - 0.0000000000000000000005157 108.0
HFD2_k127_8010261_48 plasmid stabilization protein K21495 - - 0.000000000000000000004305 94.0
HFD2_k127_8010261_49 Cupin 2, conserved barrel domain protein K11477 - - 0.000000000000000002031 93.0
HFD2_k127_8010261_5 Belongs to the glycosyl hydrolase 2 family K01190 - 3.2.1.23 1.153e-214 717.0
HFD2_k127_8010261_50 helix_turn_helix, Lux Regulon - - - 0.000000000000000003731 94.0
HFD2_k127_8010261_51 Kelch motif - - - 0.0000000000000007973 92.0
HFD2_k127_8010261_52 protein conserved in bacteria - - - 0.000000000007103 75.0
HFD2_k127_8010261_53 COG2706 3-carboxymuconate cyclase K07404 - 3.1.1.31 0.00001931 57.0
HFD2_k127_8010261_54 Methyltransferase type 11 K07755 - 2.1.1.137 0.00002975 49.0
HFD2_k127_8010261_55 Putative zinc-finger - - - 0.0005265 51.0
HFD2_k127_8010261_56 - - - - 0.0007048 51.0
HFD2_k127_8010261_6 beta-galactosidase activity K12308 - 3.2.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007168 552.0
HFD2_k127_8010261_7 Major Facilitator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 531.0
HFD2_k127_8010261_8 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 506.0
HFD2_k127_8010261_9 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 540.0
HFD2_k127_8042985_0 PFAM Alpha amylase, catalytic domain K01176 - 3.2.1.1 1.473e-203 659.0
HFD2_k127_8042985_1 Amino acid kinase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007597 462.0
HFD2_k127_8042985_10 Acyltransferase - - - 0.0000000000000000000000000000000000000000000000001288 183.0
HFD2_k127_8042985_11 PFAM glycosyl transferase family 2 K07011 - - 0.00000000000000000000000000000000000000000005373 174.0
HFD2_k127_8042985_12 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000005231 166.0
HFD2_k127_8042985_13 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000008705 157.0
HFD2_k127_8042985_14 DNA-binding transcription factor activity - - - 0.000000000000000000000000000000000003267 149.0
HFD2_k127_8042985_15 curli production assembly transport component CsgG - - - 0.000000000000000000000000000001349 130.0
HFD2_k127_8042985_16 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.0000000000000000000000005868 111.0
HFD2_k127_8042985_17 (ABC) transporter K15738 - - 0.00000000000001061 77.0
HFD2_k127_8042985_18 Glycosyl hydrolases family 16 - - - 0.0000000000002777 70.0
HFD2_k127_8042985_19 Virulence factor BrkB K07058 - - 0.00000000003284 77.0
HFD2_k127_8042985_2 peptidase K07386 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008405 473.0
HFD2_k127_8042985_22 Belongs to the glycosyl hydrolase 30 family K01201 - 3.2.1.45 0.000007295 55.0
HFD2_k127_8042985_3 GDP-mannose 4,6 dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 469.0
HFD2_k127_8042985_4 Bacterial sugar transferase K03606 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 440.0
HFD2_k127_8042985_5 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 363.0
HFD2_k127_8042985_6 PFAM heat shock protein DnaJ domain protein K03686,K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001312 276.0
HFD2_k127_8042985_7 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001066 284.0
HFD2_k127_8042985_8 COG1335 Amidases related to nicotinamidase - - - 0.000000000000000000000000000000000000000000000000000000000000142 223.0
HFD2_k127_8042985_9 COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes - - - 0.0000000000000000000000000000000000000000000000000000000008576 210.0
HFD2_k127_8064411_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003746 546.0
HFD2_k127_8064411_1 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000009122 253.0
HFD2_k127_8084689_0 CoA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006362 630.0
HFD2_k127_8084689_1 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 502.0
HFD2_k127_8084689_10 ABC-2 type transporter K01992,K09690 - - 0.00000000000000000000000000000000000000000000001437 181.0
HFD2_k127_8084689_11 DUF based on E. rectale Gene description (DUF3880) K06320 - - 0.000000000000000000000000000000000000003945 167.0
HFD2_k127_8084689_13 Insulinase (Peptidase family M16) K07263 - - 0.0000004326 61.0
HFD2_k127_8084689_14 - - - - 0.000001856 61.0
HFD2_k127_8084689_15 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00007561 54.0
HFD2_k127_8084689_2 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003563 482.0
HFD2_k127_8084689_3 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 445.0
HFD2_k127_8084689_4 LVIVD repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 397.0
HFD2_k127_8084689_5 Isoprenylcysteine carboxyl methyltransferase (ICMT) family K21310 - 2.1.1.334 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007371 317.0
HFD2_k127_8084689_6 PFAM Glucose Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005259 328.0
HFD2_k127_8084689_7 ATPases associated with a variety of cellular activities K01990,K09689,K09691 - 3.6.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000004962 269.0
HFD2_k127_8084689_8 3-demethylubiquinone-9 3-O-methyltransferase activity K20444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002567 273.0
HFD2_k127_8084689_9 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000001576 228.0
HFD2_k127_8093139_0 cellulose binding - - - 0.0 1227.0
HFD2_k127_8093139_1 PFAM BNR Asp-box repeat - - - 4.314e-271 879.0
HFD2_k127_8093139_10 COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000601 319.0
HFD2_k127_8093139_11 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989,K02428 - 2.7.7.56,3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 336.0
HFD2_k127_8093139_12 RsgA GTPase K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007261 314.0
HFD2_k127_8093139_13 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 301.0
HFD2_k127_8093139_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001842 274.0
HFD2_k127_8093139_15 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000002442 247.0
HFD2_k127_8093139_16 helix_turn_helix, mercury resistance K22491 - - 0.000000000000000000000000000000000000000000000000000000000000002109 229.0
HFD2_k127_8093139_17 3-5 exonuclease K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000004025 217.0
HFD2_k127_8093139_18 Transglycosylase SLT domain K08309 - - 0.000000000000000000000000000000000000000000000000000000000000434 238.0
HFD2_k127_8093139_19 PFAM HhH-GPD K07457 - - 0.0000000000000000000000000000000000000000000000000000001464 220.0
HFD2_k127_8093139_2 PFAM aminotransferase, class I K10907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008613 509.0
HFD2_k127_8093139_20 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000002675 195.0
HFD2_k127_8093139_21 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000001983 204.0
HFD2_k127_8093139_22 Secreted surface protein with fasciclin-like repeats - - - 0.00000000000000000000000000000000000000000000000001848 183.0
HFD2_k127_8093139_23 Nucleotidyl transferase K00966 - 2.7.7.13 0.00000000000000000000000000000000000000000000000004955 201.0
HFD2_k127_8093139_24 Cupin domain - - - 0.00000000000000000000000000000000000000000003346 166.0
HFD2_k127_8093139_25 arylsulfatase A - - - 0.0000000000000000000000000000000000000000001374 182.0
HFD2_k127_8093139_26 - - - - 0.00000000000000000000000000000000000009282 154.0
HFD2_k127_8093139_27 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000173 153.0
HFD2_k127_8093139_28 Calcium/calmodulin dependent protein kinase II association domain - - - 0.0000000000000000000000000000008313 137.0
HFD2_k127_8093139_29 CYTH K05873 - 4.6.1.1 0.00000000000000000000000000001259 124.0
HFD2_k127_8093139_3 PFAM DNA photolyase, FAD-binding K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004035 493.0
HFD2_k127_8093139_30 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.0000000000000000000000000003547 120.0
HFD2_k127_8093139_31 Sporulation and spore germination - - - 0.00000000000000000000000003777 115.0
HFD2_k127_8093139_32 Di-haem oxidoreductase, putative peroxidase - - - 0.00000000000000000003484 95.0
HFD2_k127_8093139_33 nuclear chromosome segregation - - - 0.0000000000000000000381 104.0
HFD2_k127_8093139_34 Protein of unknown function (DUF1722) - - - 0.00000000000000000006566 92.0
HFD2_k127_8093139_35 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000001393 96.0
HFD2_k127_8093139_36 - - - - 0.00000000002077 66.0
HFD2_k127_8093139_37 - - - - 0.0000000001686 70.0
HFD2_k127_8093139_38 COG1226 Kef-type K transport systems - - - 0.00000001963 66.0
HFD2_k127_8093139_39 GDSL-like Lipase/Acylhydrolase - - - 0.00000009107 60.0
HFD2_k127_8093139_4 cytochrome C peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 471.0
HFD2_k127_8093139_40 - - - - 0.0004763 51.0
HFD2_k127_8093139_5 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 464.0
HFD2_k127_8093139_6 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 436.0
HFD2_k127_8093139_7 ErfK YbiS YcfS YnhG family protein K21470 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 423.0
HFD2_k127_8093139_8 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 391.0
HFD2_k127_8093139_9 type II secretion system protein E K02454,K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 346.0
HFD2_k127_8099506_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 2.148e-268 835.0
HFD2_k127_8099506_1 COG0798 Arsenite efflux pump ACR3 and related K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 521.0
HFD2_k127_8099506_10 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000004673 123.0
HFD2_k127_8099506_11 - - - - 0.000000000000000000009287 98.0
HFD2_k127_8099506_12 Transcriptional regulator K03892,K21903 - - 0.00000000000000000002211 96.0
HFD2_k127_8099506_13 TIGRFAM redox-active disulfide protein 2 - - - 0.000000000000000004877 87.0
HFD2_k127_8099506_14 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.000000000000002158 85.0
HFD2_k127_8099506_15 long-chain fatty acid transporting porin activity K06076 - - 0.00003482 56.0
HFD2_k127_8099506_16 AAA ATPase domain - - - 0.0001345 54.0
HFD2_k127_8099506_17 DNA segregation ATPase FtsK SpoIIIE K03466 - - 0.0004926 53.0
HFD2_k127_8099506_2 Aromatic amino acid lyase K01745 - 4.3.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 527.0
HFD2_k127_8099506_3 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000322 477.0
HFD2_k127_8099506_4 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002103 445.0
HFD2_k127_8099506_5 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004176 465.0
HFD2_k127_8099506_6 PFAM permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 403.0
HFD2_k127_8099506_7 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 387.0
HFD2_k127_8099506_8 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 355.0
HFD2_k127_8099506_9 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000009144 186.0
HFD2_k127_8134725_0 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 2.101e-261 822.0
HFD2_k127_8134725_1 B12 binding domain - - - 2.814e-231 725.0
HFD2_k127_8134725_10 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000004294 161.0
HFD2_k127_8134725_11 histidine kinase HAMP region domain protein - - - 0.000000000000000000000000000000000000000601 169.0
HFD2_k127_8134725_12 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000005503 136.0
HFD2_k127_8134725_13 DNA-binding transcription factor activity - - - 0.000000000000000000000000001402 131.0
HFD2_k127_8134725_14 FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000002652 113.0
HFD2_k127_8134725_15 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.00000000000000000000006864 115.0
HFD2_k127_8134725_16 Hemerythrin HHE cation binding domain - - - 0.00000000000000001517 95.0
HFD2_k127_8134725_17 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000001454 70.0
HFD2_k127_8134725_18 - - - - 0.00000436 52.0
HFD2_k127_8134725_2 peptidase S9B dipeptidylpeptidase IV domain protein K01278 - 3.4.14.5 2.079e-199 644.0
HFD2_k127_8134725_3 Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003347 555.0
HFD2_k127_8134725_4 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006622 431.0
HFD2_k127_8134725_5 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009411 419.0
HFD2_k127_8134725_6 PFAM sigma-54 factor interaction domain-containing protein K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 404.0
HFD2_k127_8134725_7 Transmembrane secretion effector K08225 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 339.0
HFD2_k127_8134725_8 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000001611 278.0
HFD2_k127_8134725_9 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000722 220.0
HFD2_k127_8196949_0 PFAM Amidohydrolase family K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003262 348.0
HFD2_k127_8196949_1 ATPase activity K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007815 314.0
HFD2_k127_8196949_10 MOSC N-terminal beta barrel domain K07140 - - 0.00000000000000000000000000000001306 132.0
HFD2_k127_8196949_11 Metallo-peptidase family M12 - - - 0.000000000000000000000000000001041 139.0
HFD2_k127_8196949_12 DivIVA protein K04074 - - 0.00000000000000000003891 97.0
HFD2_k127_8196949_13 PFAM 6-pyruvoyl tetrahydropterin K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000001092 94.0
HFD2_k127_8196949_14 YGGT family K02221 - - 0.000000000000001298 80.0
HFD2_k127_8196949_15 Belongs to the UPF0235 family K09131 - - 0.00000000000002165 83.0
HFD2_k127_8196949_16 - - - - 0.000000000003041 74.0
HFD2_k127_8196949_17 MOSC domain K07140 - - 0.000000003289 65.0
HFD2_k127_8196949_18 glycosyl transferase family 2 K20444 - - 0.000002007 59.0
HFD2_k127_8196949_19 - - - - 0.00001975 55.0
HFD2_k127_8196949_2 cellulase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001252 298.0
HFD2_k127_8196949_3 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002861 274.0
HFD2_k127_8196949_4 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000008165 257.0
HFD2_k127_8196949_5 dna ligase K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000001711 221.0
HFD2_k127_8196949_6 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000001295 224.0
HFD2_k127_8196949_7 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000005003 193.0
HFD2_k127_8196949_8 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000004685 185.0
HFD2_k127_8196949_9 - - - - 0.0000000000000000000000000000000000000001772 168.0
HFD2_k127_8213675_0 ThiF family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 479.0
HFD2_k127_8213675_1 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01697,K01738,K12339 - 2.5.1.47,4.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000996 316.0
HFD2_k127_8213675_2 Belongs to the sulfate adenylyltransferase family K00958 GO:0000096,GO:0000103,GO:0003674,GO:0003824,GO:0004779,GO:0004781,GO:0006082,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010134,GO:0016740,GO:0016772,GO:0016779,GO:0019379,GO:0019419,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0070566,GO:0071704,GO:1901564 2.7.7.4 0.000000000000000000000000000000000000000003812 163.0
HFD2_k127_8213675_3 Molybdopterin converting factor, small subunit K03636 - - 0.000000000000000000000001506 112.0
HFD2_k127_8213675_4 JAB/MPN domain K21140 - 3.13.1.6 0.0000000000000000000003934 100.0
HFD2_k127_8254444_0 NapC/NirT cytochrome c family, N-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 537.0
HFD2_k127_8254444_1 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282,K18008 - 1.12.2.1,1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 500.0
HFD2_k127_8254444_11 recombinase activity - - - 0.00000007109 57.0
HFD2_k127_8254444_2 Cytochrome c3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004808 388.0
HFD2_k127_8254444_3 formate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004005 328.0
HFD2_k127_8254444_4 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009918 291.0
HFD2_k127_8254444_5 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 302.0
HFD2_k127_8254444_6 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004717 265.0
HFD2_k127_8254444_7 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006545 266.0
HFD2_k127_8254444_8 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001641 247.0
HFD2_k127_8254444_9 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000008867 109.0
HFD2_k127_8273856_0 CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 315.0
HFD2_k127_8273856_1 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000002695 207.0
HFD2_k127_8273856_2 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000003797 95.0
HFD2_k127_8273856_3 Domain present in phytochromes and cGMP-specific phosphodiesterases. K12266 - - 0.0007184 52.0
HFD2_k127_8301751_0 Methionine biosynthesis protein MetW K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000005537 233.0
HFD2_k127_8301751_1 Protoporphyrinogen oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000006404 240.0
HFD2_k127_8301751_2 Glycosyl transferase family 2 - - - 0.00000000000000851 79.0
HFD2_k127_8342670_0 Involved in the tonB-independent uptake of proteins - - - 1.333e-230 769.0
HFD2_k127_8342670_1 ABC-type transport system involved in lipoprotein release permease component K02004 - - 3.673e-228 743.0
HFD2_k127_8342670_10 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000002083 235.0
HFD2_k127_8342670_11 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000003652 235.0
HFD2_k127_8342670_12 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.0000000000000000000000000000000000000000000000000000000000008137 228.0
HFD2_k127_8342670_13 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.0000000000000000000000000000000000000000000000000000000004296 222.0
HFD2_k127_8342670_14 Cupin 2, conserved barrel domain protein K16953,K19547 - 4.4.1.3,5.3.3.19 0.0000000000000000000001271 104.0
HFD2_k127_8342670_2 secondary active sulfate transmembrane transporter activity K06901 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 511.0
HFD2_k127_8342670_3 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008437 424.0
HFD2_k127_8342670_4 COGs COG0515 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005841 379.0
HFD2_k127_8342670_5 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009873 360.0
HFD2_k127_8342670_6 beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006987 320.0
HFD2_k127_8342670_7 HlyD family secretion protein K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 327.0
HFD2_k127_8342670_8 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002965 259.0
HFD2_k127_8342670_9 NAD dependent epimerase/dehydratase family K07535 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002409 246.0
HFD2_k127_8373817_0 DinB superfamily K18912 - 1.14.99.50 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005719 386.0
HFD2_k127_8373817_1 BlaR1 peptidase M56 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005123 346.0
HFD2_k127_8373817_2 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000005954 219.0
HFD2_k127_8373817_3 - - - - 0.00000000000000000000000000000000000000000000000001536 192.0
HFD2_k127_8373817_4 Peptidase M56 - - - 0.0000000000000000000000000000000000000000000000006285 201.0
HFD2_k127_8373817_5 DinB superfamily - - - 0.00000000000000000000000000000000000000009963 156.0
HFD2_k127_8373817_6 Penicillinase repressor - - - 0.0000000000000000000000000000000000001253 154.0
HFD2_k127_8386885_0 Oligopeptide transporter OPT - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 595.0
HFD2_k127_8386885_1 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007172 457.0
HFD2_k127_8386885_10 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000005473 120.0
HFD2_k127_8386885_12 Lactonase, 7-bladed beta-propeller - - - 0.0004316 51.0
HFD2_k127_8386885_2 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006499 369.0
HFD2_k127_8386885_3 Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 363.0
HFD2_k127_8386885_4 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 309.0
HFD2_k127_8386885_5 Inorganic pyrophosphatase K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 289.0
HFD2_k127_8386885_6 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000004302 268.0
HFD2_k127_8386885_7 dTDP biosynthetic process K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000009271 244.0
HFD2_k127_8386885_8 Domain of unknown function (DUF4956) - - - 0.00000000000000000000000000000000000000000000000000168 197.0
HFD2_k127_8386885_9 Pyridoxal-dependent decarboxylase conserved domain K13745 - 4.1.1.86 0.000000000000000000000000000000000000000000000000003344 187.0
HFD2_k127_8404656_0 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 4.948e-230 722.0
HFD2_k127_8404656_1 Heat shock 70 kDa protein K04043 - - 3.514e-220 699.0
HFD2_k127_8404656_10 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 315.0
HFD2_k127_8404656_11 Phosphate acetyl/butaryl transferase K00625,K02028 - 2.3.1.8,3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009516 303.0
HFD2_k127_8404656_12 alpha beta alpha domain I K00966,K16881 - 2.7.7.13,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 304.0
HFD2_k127_8404656_13 HrcA protein C terminal domain K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001412 277.0
HFD2_k127_8404656_14 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000111 268.0
HFD2_k127_8404656_15 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008714 267.0
HFD2_k127_8404656_16 16S rRNA methyltransferase RsmB/F K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000005251 228.0
HFD2_k127_8404656_17 Protein of unknown function (DUF3810) - - - 0.00000000000000000000000000000000000000000000000000000000007349 219.0
HFD2_k127_8404656_18 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000001501 188.0
HFD2_k127_8404656_19 RNA methyltransferase K09761 - 2.1.1.193 0.00000000000000000000000000000000000000003402 170.0
HFD2_k127_8404656_2 UDP binding domain K02474,K13015 - 1.1.1.136 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009647 547.0
HFD2_k127_8404656_20 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000000000000006932 161.0
HFD2_k127_8404656_21 Outer membrane lipoprotein K05807,K08309 GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.0000000000000000000000000000000000000007179 162.0
HFD2_k127_8404656_22 positive regulation of growth rate - - - 0.0000000000000000000000000000000007692 145.0
HFD2_k127_8404656_23 Methylates ribosomal protein L11 K02687 - - 0.0000000000000000000000000000004017 135.0
HFD2_k127_8404656_24 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000000601 126.0
HFD2_k127_8404656_25 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000008085 122.0
HFD2_k127_8404656_26 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.00000000000000000000000001037 126.0
HFD2_k127_8404656_27 Polymer-forming cytoskeletal - - - 0.0000000000000000000003573 104.0
HFD2_k127_8404656_28 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000007717 84.0
HFD2_k127_8404656_3 alpha beta alpha domain I K01840 - 5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 503.0
HFD2_k127_8404656_4 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 475.0
HFD2_k127_8404656_5 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007908 420.0
HFD2_k127_8404656_6 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007087 399.0
HFD2_k127_8404656_7 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000605 400.0
HFD2_k127_8404656_8 Polysaccharide biosynthesis protein K01784,K08679 - 5.1.3.2,5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 357.0
HFD2_k127_8404656_9 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 345.0
HFD2_k127_8442703_0 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.000000000000000000000000000000000000000000000000000000005269 210.0
HFD2_k127_8442703_1 Telomere recombination K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000002306 164.0
HFD2_k127_8442703_2 Haloacid dehalogenase domain protein hydrolase, type 3 - - - 0.000000000000000000000000000000001209 143.0
HFD2_k127_8454155_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1103.0
HFD2_k127_8454155_1 RHS protein - - - 0.0 1088.0
HFD2_k127_8454155_11 pyrroloquinoline quinone binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001701 268.0
HFD2_k127_8454155_12 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000001009 230.0
HFD2_k127_8454155_13 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000000000000000006049 198.0
HFD2_k127_8454155_14 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.0000000000000000000000000000000000000000000000005325 180.0
HFD2_k127_8454155_15 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000002672 173.0
HFD2_k127_8454155_16 Glycosyl hydrolase-like 10 - - - 0.00000000000000000000000000002255 136.0
HFD2_k127_8454155_17 MarR family - - - 0.0000000000000000000000000002222 120.0
HFD2_k127_8454155_18 Transposase K07486 - - 0.000000000000000000004939 96.0
HFD2_k127_8454155_19 FlgD Ig-like domain - - - 0.00000000000000000001583 107.0
HFD2_k127_8454155_2 Voltage gated chloride channel - - - 7.773e-257 807.0
HFD2_k127_8454155_20 TIGRFAM TonB K03832 - - 0.00000000000000000519 93.0
HFD2_k127_8454155_21 WD40 domain protein beta Propeller - - - 0.00000000000000001667 97.0
HFD2_k127_8454155_22 Fibronectin type 3 domain - - - 0.0000000000003492 78.0
HFD2_k127_8454155_23 Transposase K07486 - - 0.00003674 55.0
HFD2_k127_8454155_24 COGs COG3547 Transposase and inactivated derivatives - - - 0.0001854 49.0
HFD2_k127_8454155_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009405,GO:0009605,GO:0009607,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030312,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0035821,GO:0036094,GO:0040007,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043207,GO:0043492,GO:0043952,GO:0044003,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0050896,GO:0051179,GO:0051234,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052564,GO:0052572,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0075136,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 1.432e-248 792.0
HFD2_k127_8454155_4 HELICc2 K03722 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006482 583.0
HFD2_k127_8454155_5 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 572.0
HFD2_k127_8454155_6 Parallel beta-helix repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 574.0
HFD2_k127_8454155_7 oligopeptide transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 510.0
HFD2_k127_8454155_8 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004424 357.0
HFD2_k127_8454155_9 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 354.0
HFD2_k127_849878_0 carboxylic acid catabolic process K18334 - 4.2.1.68 3.314e-203 640.0
HFD2_k127_849878_1 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 297.0
HFD2_k127_849878_2 transmembrane transporter activity K08191 - - 0.0000000000000000000000000000000000000000000000000000000000001945 235.0
HFD2_k127_8515319_0 antibiotic biosynthetic process K01434 - 3.5.1.11 6.026e-224 722.0
HFD2_k127_8515319_1 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004961 570.0
HFD2_k127_8515319_2 Glycosyl hydrolase family 10 K01181 - 3.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 403.0
HFD2_k127_8515319_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004912 270.0
HFD2_k127_8515319_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000001022 236.0
HFD2_k127_8515319_5 IstB-like ATP binding protein K02315 - - 0.00000000000000000000000000000000000000000000000000002496 209.0
HFD2_k127_8515319_6 Transcriptional regulator, MerR family K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000007914 147.0
HFD2_k127_8515319_7 - - - - 0.000000001849 72.0
HFD2_k127_8530358_0 Major Facilitator Superfamily K02445,K07783 - - 2.616e-213 676.0
HFD2_k127_8530358_1 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 369.0
HFD2_k127_8530358_11 Membrane - - - 0.00000001399 66.0
HFD2_k127_8530358_12 Carboxypeptidase regulatory-like domain - - - 0.000148 51.0
HFD2_k127_8530358_2 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007889 388.0
HFD2_k127_8530358_3 Mannitol dehydrogenase K00009 - 1.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000001603 264.0
HFD2_k127_8530358_4 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.00000000000000000000000000000000000000001139 159.0
HFD2_k127_8530358_5 RimK-like ATP-grasp domain K05844 - - 0.00000000000000000000000000000000000002896 155.0
HFD2_k127_8530358_6 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K01955,K05844 - 6.3.5.5 0.000000000000000000000000000000000006192 155.0
HFD2_k127_8530358_7 - K12065 - - 0.000000000000000000000000000000008682 146.0
HFD2_k127_8530358_8 RimK-like ATP-grasp domain K05844 - - 0.0000000000000000000000000716 124.0
HFD2_k127_8530358_9 RimK-like ATP-grasp domain K05844 - - 0.00000000000000000000002461 116.0
HFD2_k127_8571105_0 Glycosyl hydrolase family 10 K01181 - 3.2.1.8 2.698e-252 812.0
HFD2_k127_8571105_1 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179 - 3.2.1.4 6.854e-233 744.0
HFD2_k127_8571105_10 Belongs to the Dps family K04047 - - 0.00000000000000000000000000000000000000000000000000000000000000001707 230.0
HFD2_k127_8571105_11 Thioesterase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000659 207.0
HFD2_k127_8571105_12 - - - - 0.00000000000000000000000000000000000000000000000003425 185.0
HFD2_k127_8571105_13 lipoprotein involved in nitrous oxide reduction K19342 - - 0.00000000000000000000000000000000000000001604 169.0
HFD2_k127_8571105_14 nuclease activity K18828 - - 0.000000000000000000000000000000000000001374 152.0
HFD2_k127_8571105_15 helix_turn_helix, cAMP Regulatory protein K21564 - - 0.000000000000000000000000000000000006802 145.0
HFD2_k127_8571105_16 Belongs to the heme-copper respiratory oxidase family - - - 0.000000000000000000000000000000000009445 153.0
HFD2_k127_8571105_18 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000001392 99.0
HFD2_k127_8571105_19 HEAT repeats - - - 0.0000000000000003612 94.0
HFD2_k127_8571105_2 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 526.0
HFD2_k127_8571105_20 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K01179 - 3.2.1.4 0.0000000001222 76.0
HFD2_k127_8571105_21 - - - - 0.0000006749 59.0
HFD2_k127_8571105_22 - - - - 0.00001745 50.0
HFD2_k127_8571105_3 LVIVD repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 529.0
HFD2_k127_8571105_4 alpha/beta hydrolase fold K00641 - 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006324 466.0
HFD2_k127_8571105_5 Protein conserved in bacteria K20276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062 466.0
HFD2_k127_8571105_6 ABC transporter K01990,K19340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 337.0
HFD2_k127_8571105_7 Rhamnogalacturonan lyase B, N-terminal K18195 - 4.2.2.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 351.0
HFD2_k127_8571105_8 ABC-2 family transporter protein K19341 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007872 301.0
HFD2_k127_8571105_9 Periplasmic component of the Tol biopolymer transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009798 282.0
HFD2_k127_859650_0 CoA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008421 599.0
HFD2_k127_859650_1 PFAM Glycosyl transferase family 4 K13007 - - 0.00000000000000000000000000000000000000002649 164.0
HFD2_k127_8653136_0 Aldehyde dehydrogenase family K00128,K00135 - 1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 606.0
HFD2_k127_8653136_1 Extradiol ring-cleavage dioxygenase K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 394.0
HFD2_k127_8653136_10 (Rhomboid) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000002477 236.0
HFD2_k127_8653136_11 metal-dependent phosphohydrolase HD region - - - 0.0000000000000000000000000000000000000000000000000000000003963 221.0
HFD2_k127_8653136_12 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000000000000000000000001115 178.0
HFD2_k127_8653136_13 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000001712 187.0
HFD2_k127_8653136_14 Domain of Unknown Function (DUF1206) - - - 0.000000000000000000000000000000000000000000004238 175.0
HFD2_k127_8653136_15 PFAM OsmC family protein K04063 - - 0.00000000000000000000000000000000000000006004 174.0
HFD2_k127_8653136_16 DoxX - - - 0.000000000000000000000000000000000000006683 149.0
HFD2_k127_8653136_17 Thioredoxin - - - 0.000000000000000000000005107 113.0
HFD2_k127_8653136_18 COG2010 Cytochrome c, mono- and diheme variants - - - 0.000000000000000000009633 98.0
HFD2_k127_8653136_19 Cyclic nucleotide-monophosphate binding domain K04739 - - 0.00000000000000000001507 107.0
HFD2_k127_8653136_2 MscS Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008089 404.0
HFD2_k127_8653136_20 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000001074 81.0
HFD2_k127_8653136_21 - - - - 0.000001165 57.0
HFD2_k127_8653136_3 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005691 392.0
HFD2_k127_8653136_4 Sigma-54 interaction domain K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 383.0
HFD2_k127_8653136_5 zinc metallopeptidase K07054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 356.0
HFD2_k127_8653136_6 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 GO:0003674,GO:0003824,GO:0004766,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0010487,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0043918,GO:0043919,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0050314,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 355.0
HFD2_k127_8653136_7 HD domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 315.0
HFD2_k127_8653136_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004446 291.0
HFD2_k127_8653136_9 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000001702 244.0
HFD2_k127_8660137_0 Belongs to the PEP-utilizing enzyme family K01006,K22424 - 2.7.3.13,2.7.9.1 0.0 1075.0
HFD2_k127_8660137_1 Ribosomal protein S1 K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000999 615.0
HFD2_k127_8660137_10 Oxidoreductase NAD-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001061 274.0
HFD2_k127_8660137_11 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008044 278.0
HFD2_k127_8660137_12 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000004371 226.0
HFD2_k127_8660137_13 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000004898 241.0
HFD2_k127_8660137_14 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000001798 226.0
HFD2_k127_8660137_15 Diaminopimelate epimerase K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.0000000000000000000000000000000000000000000000000000009243 214.0
HFD2_k127_8660137_16 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000001207 207.0
HFD2_k127_8660137_17 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.0000000000000000000000000000000000000000000000001326 181.0
HFD2_k127_8660137_18 radical SAM domain protein - - - 0.0000000000000000000000000000000000581 150.0
HFD2_k127_8660137_19 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.000000000000000000000000000000006364 130.0
HFD2_k127_8660137_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000598 417.0
HFD2_k127_8660137_20 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000003335 116.0
HFD2_k127_8660137_21 Involved in DNA repair and RecF pathway recombination K03584 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000006143 103.0
HFD2_k127_8660137_22 Cation efflux family K16264 - - 0.00000000000000005507 95.0
HFD2_k127_8660137_23 - - - - 0.000000000000000522 89.0
HFD2_k127_8660137_24 Rhodanese Homology Domain - - - 0.000000000000006363 81.0
HFD2_k127_8660137_25 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000006197 85.0
HFD2_k127_8660137_26 protein histidine kinase activity K01768,K13924 - 2.1.1.80,3.1.1.61,4.6.1.1 0.0000000000008602 81.0
HFD2_k127_8660137_27 TIGRFAM hydrogenase maturation protease K03605 - - 0.0000006587 62.0
HFD2_k127_8660137_3 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006453 389.0
HFD2_k127_8660137_4 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005673 372.0
HFD2_k127_8660137_5 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006926 366.0
HFD2_k127_8660137_6 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 336.0
HFD2_k127_8660137_7 hydrogenase large subunit K00436 - 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 327.0
HFD2_k127_8660137_8 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007888 319.0
HFD2_k127_8660137_9 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001436 290.0
HFD2_k127_8680390_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 0.0 1048.0
HFD2_k127_8680390_1 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 8.641e-289 917.0
HFD2_k127_8680390_10 phosphate ion binding - - - 0.00000000000000000000000001189 117.0
HFD2_k127_8680390_11 - - - - 0.00000000029 74.0
HFD2_k127_8680390_12 PilZ domain - - - 0.0001433 55.0
HFD2_k127_8680390_2 glutamate dehydrogenase [NAD(P)+] activity K00262 - 1.4.1.4 1.702e-242 761.0
HFD2_k127_8680390_3 glutamate dehydrogenase [NAD(P)+] activity K00260,K00261,K00262 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.2,1.4.1.3,1.4.1.4 1.031e-223 701.0
HFD2_k127_8680390_4 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004707 582.0
HFD2_k127_8680390_5 phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 574.0
HFD2_k127_8680390_6 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002791 514.0
HFD2_k127_8680390_7 Elongation factor SelB winged helix K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005009 469.0
HFD2_k127_8680390_8 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009628 303.0
HFD2_k127_8680390_9 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000002534 198.0
HFD2_k127_8689139_0 PFAM Permease for cytosine purines, uracil, thiamine, allantoin K03457 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 594.0
HFD2_k127_8689139_1 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004671 318.0
HFD2_k127_8689139_2 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000008746 248.0
HFD2_k127_8689139_3 Adenylate cyclase - - - 0.000000000000002676 85.0
HFD2_k127_8689139_4 FHA domain containing protein - GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363 - 0.00000000000003018 82.0
HFD2_k127_8689139_5 phosphatidylinositol metabolic process K13671,K16647 - 2.4.2.47 0.00000009571 64.0
HFD2_k127_8689139_6 Nacht domain - - - 0.00007737 55.0
HFD2_k127_8689139_7 PFAM PEGA domain - - - 0.0003186 50.0
HFD2_k127_8689139_8 ECF sigma factor K03088 - - 0.0009532 50.0
HFD2_k127_8695875_0 Carboxypeptidase regulatory-like domain - - - 2.533e-267 862.0
HFD2_k127_8695875_1 Trehalase K01194 - 3.2.1.28 4.005e-200 658.0
HFD2_k127_8695875_2 BAAT / Acyl-CoA thioester hydrolase C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004323 348.0
HFD2_k127_8695875_3 PFAM Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000004263 159.0
HFD2_k127_8695875_4 Protein of unknown function (DUF3179) - - - 0.0000000000000000000000000006478 130.0
HFD2_k127_8695875_5 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.000000001428 71.0
HFD2_k127_8695875_6 serine threonine protein kinase K00870,K12132 - 2.7.1.37,2.7.11.1 0.0000000935 64.0
HFD2_k127_8742620_0 peptidase K01415,K07386 - 3.4.24.71 3.462e-278 871.0
HFD2_k127_8742620_1 beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006413 423.0
HFD2_k127_8742620_10 - - - - 0.00000000000000008123 91.0
HFD2_k127_8742620_11 Alpha-L-arabinofuranosidase K01209 - 3.2.1.55 0.00000000000001867 87.0
HFD2_k127_8742620_12 Fibronectin type 3 domain - - - 0.0000000001751 74.0
HFD2_k127_8742620_13 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000001023 64.0
HFD2_k127_8742620_14 Cytochrome oxidase complex assembly protein 1 - - - 0.000000001868 70.0
HFD2_k127_8742620_15 Bacterial Ig-like domain (group 3) K20276 - - 0.000166 55.0
HFD2_k127_8742620_2 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000572 395.0
HFD2_k127_8742620_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003421 350.0
HFD2_k127_8742620_4 Phosphoenolpyruvate phosphomutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 348.0
HFD2_k127_8742620_5 Lytic polysaccharide mono-oxygenase, cellulose-degrading K03933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005262 365.0
HFD2_k127_8742620_6 Pkd domain containing protein K01337 - 3.4.21.50 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 317.0
HFD2_k127_8742620_7 Pyridoxamine 5'-phosphate oxidase K07226 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001524 278.0
HFD2_k127_8742620_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000148 259.0
HFD2_k127_8742620_9 Tryptophan halogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000009488 255.0
HFD2_k127_883116_0 3-demethylubiquinone-9 3-O-methyltransferase activity K00568,K20444 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004053 589.0
HFD2_k127_883116_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 495.0
HFD2_k127_883116_10 Protein conserved in bacteria K12992,K20444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002603 276.0
HFD2_k127_883116_11 MazG nucleotide pyrophosphohydrolase domain K02499,K04765 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009267,GO:0009394,GO:0009605,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042594,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000003716 263.0
HFD2_k127_883116_12 cephalosporin hydroxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009808 258.0
HFD2_k127_883116_13 3'-5' exonuclease K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000000006695 266.0
HFD2_k127_883116_14 transferase hexapeptide K13018 - 2.3.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000007225 269.0
HFD2_k127_883116_15 PFAM Glycosyl transferase family 2 K07011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002204 274.0
HFD2_k127_883116_16 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004107 250.0
HFD2_k127_883116_17 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000005584 228.0
HFD2_k127_883116_18 FR47-like protein - - - 0.00000000000000000000000000000000000000000000000007323 183.0
HFD2_k127_883116_19 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000001503 177.0
HFD2_k127_883116_2 methyltransferase activity K00574,K12240,K18534,K19620,K20444 - 2.1.1.295,2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 467.0
HFD2_k127_883116_20 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000001944 169.0
HFD2_k127_883116_21 Glycosyl transferase, family 2 K16648 - - 0.00000000000000000000000000000000000000103 172.0
HFD2_k127_883116_22 Glycosyltransferase, group 1 family protein - - - 0.000000000000000000000000000000000000003288 166.0
HFD2_k127_883116_23 CarD-like/TRCF domain K07736 - - 0.00000000000000000000000000000000000002225 152.0
HFD2_k127_883116_24 Methyltransferase K15257 - - 0.00000000000000000000000000000000214 145.0
HFD2_k127_883116_25 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.00000000000000000000000000000002697 147.0
HFD2_k127_883116_26 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.0000000000000000000000000000003276 143.0
HFD2_k127_883116_27 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.000000000000000000000004975 106.0
HFD2_k127_883116_28 nuclear chromosome segregation - - - 0.00000000000000000000004033 113.0
HFD2_k127_883116_29 Domain of unknown function (DUF4388) - - - 0.00000000000000003077 91.0
HFD2_k127_883116_3 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 439.0
HFD2_k127_883116_30 ubiE/COQ5 methyltransferase family - - - 0.0000000000002662 82.0
HFD2_k127_883116_32 Methyltransferase domain - - - 0.0000000001833 73.0
HFD2_k127_883116_33 Participates in initiation and elongation during chromosome replication K02314,K02316,K17680 - 3.6.4.12 0.000000000257 72.0
HFD2_k127_883116_34 methyltransferase K03183,K21600 - 2.1.1.163,2.1.1.201 0.0000002084 64.0
HFD2_k127_883116_35 Subtilase family - - - 0.0001945 55.0
HFD2_k127_883116_4 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005643 372.0
HFD2_k127_883116_5 Domain of unknown function (DUF4347) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000526 397.0
HFD2_k127_883116_6 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006737 348.0
HFD2_k127_883116_7 overlaps another CDS with the same product name K07011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005067 330.0
HFD2_k127_883116_8 PFAM oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005635 332.0
HFD2_k127_883116_9 isomerase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 314.0
HFD2_k127_887999_0 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007577 479.0
HFD2_k127_887999_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006082 421.0
HFD2_k127_887999_2 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 333.0
HFD2_k127_887999_3 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 324.0
HFD2_k127_887999_4 Acetamidase/Formamidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005198 291.0
HFD2_k127_887999_5 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000007063 267.0
HFD2_k127_887999_6 serine threonine protein kinase K08282,K08884,K11916,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000003709 231.0
HFD2_k127_887999_7 Probably functions as a manganese efflux pump - - - 0.00000000000000000002202 105.0
HFD2_k127_888363_0 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 551.0
HFD2_k127_888363_1 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004416 414.0
HFD2_k127_888363_10 L-asparaginase K01424 - 3.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000007305 290.0
HFD2_k127_888363_11 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000001045 244.0
HFD2_k127_888363_12 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000003538 239.0
HFD2_k127_888363_13 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000008952 206.0
HFD2_k127_888363_14 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000001269 188.0
HFD2_k127_888363_15 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000001961 184.0
HFD2_k127_888363_16 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000004454 183.0
HFD2_k127_888363_17 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000007358 157.0
HFD2_k127_888363_18 FAD binding domain K03391,K05712 - 1.14.13.127,1.14.13.50 0.000000000005954 74.0
HFD2_k127_888363_19 Adenylate cyclase - - - 0.0000002232 55.0
HFD2_k127_888363_2 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 387.0
HFD2_k127_888363_20 Domain of unknown function (DUF4190) - - - 0.0001911 55.0
HFD2_k127_888363_3 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 351.0
HFD2_k127_888363_4 PFAM peptidase S58, DmpA K01266 - 3.4.11.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003236 337.0
HFD2_k127_888363_5 symporter activity K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007821 351.0
HFD2_k127_888363_6 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007039 321.0
HFD2_k127_888363_7 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005527 320.0
HFD2_k127_888363_8 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 307.0
HFD2_k127_888363_9 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 328.0
HFD2_k127_939530_0 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004761 332.0
HFD2_k127_939530_1 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002641 271.0
HFD2_k127_939530_10 - - - - 0.000004929 52.0
HFD2_k127_939530_11 signal transduction histidine kinase - - - 0.0000105 55.0
HFD2_k127_939530_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000001384 180.0
HFD2_k127_939530_3 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.00000000000000000000000000000003203 139.0
HFD2_k127_939530_4 diguanylate cyclase K02488 - 2.7.7.65 0.0000000000000000000000000000007082 126.0
HFD2_k127_939530_6 DinB family - - - 0.000000000000000000000007123 108.0
HFD2_k127_939530_7 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000002737 107.0
HFD2_k127_939530_8 Peptidase M56 - - - 0.000000000000000007965 97.0
HFD2_k127_939530_9 PFAM PEGA domain - - - 0.000001707 60.0
HFD2_k127_946296_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1412.0
HFD2_k127_946296_1 Succinyl-CoA ligase like flavodoxin domain - - - 1.039e-229 755.0
HFD2_k127_946296_2 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 385.0
HFD2_k127_946296_3 COG3005 Nitrate TMAO reductases, membrane-bound tetraheme cytochrome c subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008174 250.0
HFD2_k127_946296_4 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.00000000000000000000000000000000000000000000003154 198.0
HFD2_k127_946296_5 DoxX-like family - - - 0.00000000000000006156 95.0
HFD2_k127_946296_6 Outer membrane efflux protein - - - 0.0006407 49.0