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Overview

ID MAG01673
Name HFD3_bin.1
Sample SMP0045
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Terriglobia
Order 20CM-2-55-15
Family 20CM-2-55-15
Genus DASTBJ01
Species
Assembly information
Completeness (%) 93.3
Contamination (%) 3.37
GC content (%) 59.0
N50 (bp) 18,045
Genome size (bp) 4,921,651

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3984

Gene name Description KEGG GOs EC E-value Score Sequence
HFD3_k127_1004989_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 637.0
HFD3_k127_1004989_2 - - - - 0.00000000000000000000000000000000000000000000000000008602 200.0
HFD3_k127_1004989_3 LytTr DNA-binding domain K02477 - - 0.00000000000000000000000000000000000000000000003456 178.0
HFD3_k127_1004989_4 InterPro IPR008538 - - - 0.0000000000000000000000000000000000000000008037 164.0
HFD3_k127_1004989_5 Signal transduction histidine kinase, LytS K02478 - 2.7.13.3 0.0000000000000000000000000000000000002212 161.0
HFD3_k127_1007082_0 Amino-acid N-acetyltransferase K14682 - 2.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 535.0
HFD3_k127_1007082_1 nucleotide-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003685 485.0
HFD3_k127_1007082_10 - - - - 0.00007211 49.0
HFD3_k127_1007082_2 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007533 314.0
HFD3_k127_1007082_3 Calcineurin-like phosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000008374 227.0
HFD3_k127_1007082_4 Conserved Protein - - - 0.00000000000000000000000000000000000000006388 159.0
HFD3_k127_1007082_5 SnoaL-like domain - - - 0.000000000000000000000000000000000000005713 147.0
HFD3_k127_1007082_6 - - - - 0.0000000000000000000000000000000000001183 150.0
HFD3_k127_1007082_7 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.000000005931 61.0
HFD3_k127_1007082_8 Protein of unknown function (DUF3738) - - - 0.0000001146 59.0
HFD3_k127_1007082_9 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.000001183 53.0
HFD3_k127_1032719_0 Dehydrogenase K00117 - 1.1.5.2 1.324e-264 829.0
HFD3_k127_1032719_1 Transcriptional Regulator, AraC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001982 257.0
HFD3_k127_1032719_2 Acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001983 244.0
HFD3_k127_1032719_3 Belongs to the glutathione peroxidase family K00432,K20207 - 1.11.1.22,1.11.1.9 0.000000000000000000000000000000000000000000000000000006532 197.0
HFD3_k127_1032719_4 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.000000000000000000000000000000000000000000000005761 180.0
HFD3_k127_1032719_5 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000000000002696 164.0
HFD3_k127_1032719_6 - - - - 0.000000000000937 73.0
HFD3_k127_1032719_7 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000009349 72.0
HFD3_k127_1032719_8 - - - - 0.00000427 60.0
HFD3_k127_1032719_9 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.00003713 54.0
HFD3_k127_103729_0 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003041 522.0
HFD3_k127_103729_1 belongs to the thioredoxin family K05838 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 464.0
HFD3_k127_103729_10 R COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000002885 173.0
HFD3_k127_103729_11 Acetyltransferase (GNAT) family - - - 0.00000000000000000165 89.0
HFD3_k127_103729_12 TPR repeat - - - 0.000000001614 71.0
HFD3_k127_103729_13 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.000000008964 59.0
HFD3_k127_103729_14 ASPIC and UnbV - - - 0.00000004667 68.0
HFD3_k127_103729_15 ASPIC and UnbV - - - 0.00000015 58.0
HFD3_k127_103729_16 peptidyl-tyrosine sulfation - - - 0.000001513 55.0
HFD3_k127_103729_17 Tetratricopeptide TPR_2 repeat protein - - - 0.000008073 58.0
HFD3_k127_103729_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 451.0
HFD3_k127_103729_3 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004321 381.0
HFD3_k127_103729_4 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005968 374.0
HFD3_k127_103729_5 cytochrome K17230 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003794 287.0
HFD3_k127_103729_6 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000167 272.0
HFD3_k127_103729_7 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000004003 216.0
HFD3_k127_103729_8 Peptidase family S51 - - - 0.00000000000000000000000000000000000000000000000000000000001874 219.0
HFD3_k127_103729_9 PepSY-associated TM region - - - 0.00000000000000000000000000000000000000000000002946 183.0
HFD3_k127_1087624_0 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007081 311.0
HFD3_k127_1087624_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000005428 135.0
HFD3_k127_1087624_2 phospholipase Carboxylesterase - - - 0.0000000000000000000000185 113.0
HFD3_k127_1087624_3 positive regulation of growth K01081 - 3.1.3.5 0.000000000001409 69.0
HFD3_k127_1087753_0 CHAT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 520.0
HFD3_k127_1087753_1 metal-dependent phosphohydrolase HD region - - - 0.000000000000000000000000000000000000000000000000000001111 199.0
HFD3_k127_1087753_2 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.0000000000000000000000000000000000000000281 169.0
HFD3_k127_1087753_3 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000007326 126.0
HFD3_k127_1087753_4 belongs to the sigma-70 factor family, ECF subfamily - - - 0.00000000000000000000000000002371 123.0
HFD3_k127_1087753_5 positive regulation of growth K01081 - 3.1.3.5 0.0000000000001108 72.0
HFD3_k127_1087753_6 Subtilase family K08651 - 3.4.21.66 0.0000000004651 63.0
HFD3_k127_1087753_7 peptidyl-glycine alpha-amidating monooxygenase K00504,K18200 GO:0000003,GO:0001519,GO:0001666,GO:0001676,GO:0002791,GO:0003674,GO:0003824,GO:0004497,GO:0004504,GO:0004598,GO:0005488,GO:0005507,GO:0005509,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0005802,GO:0005829,GO:0005886,GO:0005887,GO:0006082,GO:0006355,GO:0006357,GO:0006464,GO:0006518,GO:0006629,GO:0006631,GO:0006807,GO:0006810,GO:0006950,GO:0007275,GO:0007399,GO:0007417,GO:0007507,GO:0007565,GO:0007589,GO:0007595,GO:0008150,GO:0008152,GO:0008270,GO:0009268,GO:0009404,GO:0009628,GO:0009653,GO:0009719,GO:0009725,GO:0009887,GO:0009889,GO:0009986,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0010468,GO:0010556,GO:0012505,GO:0012506,GO:0014070,GO:0016020,GO:0016021,GO:0016043,GO:0016491,GO:0016705,GO:0016715,GO:0016829,GO:0016840,GO:0016842,GO:0018032,GO:0019219,GO:0019222,GO:0019538,GO:0019748,GO:0019752,GO:0019899,GO:0019900,GO:0019901,GO:0022414,GO:0022602,GO:0022607,GO:0030133,GO:0030141,GO:0030658,GO:0030659,GO:0030667,GO:0030879,GO:0031090,GO:0031179,GO:0031224,GO:0031226,GO:0031323,GO:0031326,GO:0031410,GO:0031960,GO:0031982,GO:0031984,GO:0032355,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032879,GO:0032880,GO:0032956,GO:0032970,GO:0033043,GO:0033993,GO:0034641,GO:0036211,GO:0036293,GO:0036477,GO:0042221,GO:0042476,GO:0042493,GO:0042698,GO:0042995,GO:0043005,GO:0043025,GO:0043167,GO:0043169,GO:0043170,GO:0043204,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043436,GO:0043603,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044297,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044433,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0044703,GO:0044706,GO:0046688,GO:0046872,GO:0046903,GO:0046914,GO:0048471,GO:0048511,GO:0048513,GO:0048545,GO:0048609,GO:0048731,GO:0048732,GO:0048736,GO:0048856,GO:0050708,GO:0050789,GO:0050794,GO:0050878,GO:0050896,GO:0051046,GO:0051049,GO:0051128,GO:0051171,GO:0051179,GO:0051223,GO:0051234,GO:0051252,GO:0051259,GO:0051260,GO:0051384,GO:0051493,GO:0051704,GO:0055114,GO:0060135,GO:0060173,GO:0060255,GO:0065003,GO:0065007,GO:0065008,GO:0070201,GO:0070482,GO:0071704,GO:0071840,GO:0071944,GO:0072359,GO:0080090,GO:0090087,GO:0097458,GO:0097708,GO:0098588,GO:0098791,GO:0098805,GO:0099503,GO:0120025,GO:0140096,GO:1901564,GO:1901700,GO:1903506,GO:1903530,GO:2000112,GO:2001141 1.14.17.3,4.3.2.5 0.00000228 51.0
HFD3_k127_1087753_8 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 0.000003697 53.0
HFD3_k127_1087818_0 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004268 299.0
HFD3_k127_1087818_1 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001488 288.0
HFD3_k127_1087818_2 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000003505 242.0
HFD3_k127_1087818_3 SnoaL-like domain - - - 0.0000000000000000000000007282 109.0
HFD3_k127_1101909_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 3.439e-285 892.0
HFD3_k127_1101909_1 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000158 239.0
HFD3_k127_1101909_2 COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and K03182 - 4.1.1.98 0.00000000000000000000000000000000000000000000000000037 190.0
HFD3_k127_1101909_3 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000005967 135.0
HFD3_k127_1101909_4 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000001855 101.0
HFD3_k127_1101909_5 Protein of unknown function (DUF503) K09764 - - 0.00000000000000001157 86.0
HFD3_k127_1112622_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 447.0
HFD3_k127_1112622_1 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000001998 233.0
HFD3_k127_1112622_2 Putative esterase - - - 0.0000000000000000000000000000000000000000000000005077 186.0
HFD3_k127_1112622_3 PFAM sigma-70 region 2 domain protein K03088 - - 0.000000000000000001499 91.0
HFD3_k127_1112622_4 Acylphosphatase K01512 GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896 3.6.1.7 0.00000000000000005577 83.0
HFD3_k127_1112622_5 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000001944 88.0
HFD3_k127_1112622_6 PFAM Rieske 2Fe-2S domain K03886 - - 0.0000000000002179 78.0
HFD3_k127_1112622_7 peroxiredoxin activity K01607 - 4.1.1.44 0.0000000001087 71.0
HFD3_k127_1112622_8 PFAM type II and III secretion system protein K02666 - - 0.0004207 45.0
HFD3_k127_1117995_0 Glycosyltransferase family 20 - - - 2.689e-195 621.0
HFD3_k127_1117995_1 Glycosyl transferases group 1 K13057 - 2.4.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 488.0
HFD3_k127_1117995_2 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000001127 166.0
HFD3_k127_1117995_3 Belongs to the ompA family K03286 - - 0.0000000000000000006766 96.0
HFD3_k127_1117995_4 - - - - 0.0000000000000007479 87.0
HFD3_k127_1131553_0 phosphatidylethanolamine metabolic process K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000001079 187.0
HFD3_k127_1131553_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000002635 187.0
HFD3_k127_1131553_2 Semialdehyde dehydrogenase K00133 - 1.2.1.11 0.0000000000000000000000000000000000000002628 163.0
HFD3_k127_1131553_3 Protein of unknown function (DUF465) - - - 0.000004655 54.0
HFD3_k127_1132311_0 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000592 177.0
HFD3_k127_1132311_1 - - - - 0.00000000000000000000000000001068 133.0
HFD3_k127_1132311_2 - - - - 0.0000000000000000000000002507 110.0
HFD3_k127_1132311_3 - - - - 0.00000000000000000001709 104.0
HFD3_k127_1132311_4 - - - - 0.000000003395 68.0
HFD3_k127_1136664_0 Metallopeptidase family M24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008601 599.0
HFD3_k127_1136664_1 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K21417 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005656 512.0
HFD3_k127_1136664_2 Dehydrogenase E1 component K21416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009904 433.0
HFD3_k127_1136664_3 Catalytic domain of components of various dehydrogenase complexes K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006752 307.0
HFD3_k127_1196042_0 Short chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006171 371.0
HFD3_k127_1196042_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 309.0
HFD3_k127_1196042_2 2OG-Fe(II) oxygenase superfamily K03919 - 1.14.11.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007217 280.0
HFD3_k127_1196042_3 PFAM ATP-binding region, ATPase domain protein K02486 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000204 222.0
HFD3_k127_1196042_4 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000001331 168.0
HFD3_k127_1196042_5 - - - - 0.00000000000000000000000002656 112.0
HFD3_k127_120513_0 Peptidase M56, BlaR1 - - - 0.000000000000000000000000000000000000000000000000001233 203.0
HFD3_k127_120513_1 Penicillinase repressor - - - 0.0000000000000000000000000000000000000000001154 164.0
HFD3_k127_1205683_0 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00956 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 487.0
HFD3_k127_1205683_1 TIGRFAM sulfate adenylyltransferase, small subunit K00957 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008883 464.0
HFD3_k127_1205711_0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0 1251.0
HFD3_k127_1205711_1 electron transport chain K00347,K03614 - 1.6.5.8 6.446e-277 862.0
HFD3_k127_1205711_10 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000001243 202.0
HFD3_k127_1205711_11 glycolate biosynthetic process K07025 - - 0.000000000000000000000000000000000000000000007257 170.0
HFD3_k127_1205711_12 Transcriptional regulator K22293 - - 0.000000000000000000000000000000000003074 147.0
HFD3_k127_1205711_13 SnoaL-like domain - - - 0.00000000000000000000000000000001094 135.0
HFD3_k127_1205711_14 DNA-templated transcription, initiation - - - 0.00000000000000000000000001248 117.0
HFD3_k127_1205711_15 - - - - 0.0000000000000000000000002331 115.0
HFD3_k127_1205711_17 YtkA-like - - - 0.000000000000002233 85.0
HFD3_k127_1205711_19 - - - - 0.0000000000008578 71.0
HFD3_k127_1205711_2 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 498.0
HFD3_k127_1205711_21 PFAM Abortive infection protein - - - 0.00000004086 57.0
HFD3_k127_1205711_3 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008834 435.0
HFD3_k127_1205711_4 Trehalose utilisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 416.0
HFD3_k127_1205711_5 electron transport chain K00347,K03614,K21163 - 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008725 393.0
HFD3_k127_1205711_6 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003356 342.0
HFD3_k127_1205711_7 Trehalose utilisation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 337.0
HFD3_k127_1205711_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001512 244.0
HFD3_k127_1205711_9 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000000000000000000000000000003331 249.0
HFD3_k127_1205766_0 methyltransferase K09846,K16034,K20421 - 2.1.1.210,2.1.1.303 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005816 448.0
HFD3_k127_1205766_1 PFAM Glucose Sorbosone dehydrogenase K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 389.0
HFD3_k127_1205766_2 Isoprenylcysteine carboxyl methyltransferase (ICMT) family K21310 - 2.1.1.334 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 313.0
HFD3_k127_1211538_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2.069e-280 883.0
HFD3_k127_1211538_1 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 2.242e-262 816.0
HFD3_k127_1211538_10 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004514 455.0
HFD3_k127_1211538_11 beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008953 438.0
HFD3_k127_1211538_12 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000423 412.0
HFD3_k127_1211538_13 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006622 404.0
HFD3_k127_1211538_14 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 386.0
HFD3_k127_1211538_15 Domain of unknown function (DUF4129) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 388.0
HFD3_k127_1211538_16 Stage II sporulation protein M - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 377.0
HFD3_k127_1211538_17 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 358.0
HFD3_k127_1211538_18 ankyrin repeat K15503 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006292 348.0
HFD3_k127_1211538_19 RDD family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000392 315.0
HFD3_k127_1211538_2 Phosphate acyltransferases K01897 - 6.2.1.3 1.11e-237 760.0
HFD3_k127_1211538_20 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006096 299.0
HFD3_k127_1211538_21 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 302.0
HFD3_k127_1211538_22 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006125 299.0
HFD3_k127_1211538_23 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009079 279.0
HFD3_k127_1211538_24 Predicted membrane protein (DUF2157) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007567 276.0
HFD3_k127_1211538_25 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000002181 224.0
HFD3_k127_1211538_26 - - - - 0.00000000000000000000000000000000000000000000000000000000002278 226.0
HFD3_k127_1211538_27 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.00000000000000000000000000000000000000000000000000000002865 202.0
HFD3_k127_1211538_28 Arabinogalactan endo-beta-1,4-galactanase K01224 - 3.2.1.89 0.0000000000000000000000000000000000000000000000000008264 198.0
HFD3_k127_1211538_29 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.000000000000000000000000000000000000000000000000001488 186.0
HFD3_k127_1211538_3 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.652e-234 730.0
HFD3_k127_1211538_30 histone acetyltransferase binding - - - 0.000000000000000000000000000000000000000000000000008521 195.0
HFD3_k127_1211538_31 RDD family - - - 0.000000000000000000000000000000000000000000001953 171.0
HFD3_k127_1211538_32 - - - - 0.00000000000000000000000000000000000000000006348 175.0
HFD3_k127_1211538_33 Predicted membrane protein (DUF2127) - - - 0.0000000000000000000000000000000000000001083 156.0
HFD3_k127_1211538_34 - - - - 0.0000000000000000000000000000000000000006835 153.0
HFD3_k127_1211538_35 - - - - 0.000000000000000000000000000000000000008126 151.0
HFD3_k127_1211538_36 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.000000000000000000000000000000000003172 149.0
HFD3_k127_1211538_37 Arabinogalactan K01224 - 3.2.1.89 0.000000000000000000000000000000000004879 147.0
HFD3_k127_1211538_38 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000001004 139.0
HFD3_k127_1211538_39 - - - - 0.000000000000000000000000000000004958 141.0
HFD3_k127_1211538_4 Amidase K02433 - 6.3.5.6,6.3.5.7 1.052e-204 653.0
HFD3_k127_1211538_40 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000002032 129.0
HFD3_k127_1211538_42 - - - - 0.0000000000000000000000000007939 117.0
HFD3_k127_1211538_43 - - - - 0.00000000000000000000008444 112.0
HFD3_k127_1211538_44 - - - - 0.0000000000000000000005559 108.0
HFD3_k127_1211538_46 tRNA (guanine-N7-)-methyltransferase activity K18846 - 2.1.1.180 0.0000000000000000005409 94.0
HFD3_k127_1211538_47 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000000000642 91.0
HFD3_k127_1211538_48 - - - - 0.000000000000000008997 87.0
HFD3_k127_1211538_49 - - - - 0.00000000000000002734 92.0
HFD3_k127_1211538_5 Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007867 571.0
HFD3_k127_1211538_50 - - - - 0.0000000000000006411 85.0
HFD3_k127_1211538_51 - - - - 0.000000000004232 78.0
HFD3_k127_1211538_52 - - - - 0.0000000007488 69.0
HFD3_k127_1211538_54 DNA-sulfur modification-associated - - - 0.0000037 59.0
HFD3_k127_1211538_55 salt-induced outer membrane protein K07283 - - 0.0005664 51.0
HFD3_k127_1211538_6 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 557.0
HFD3_k127_1211538_7 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003064 539.0
HFD3_k127_1211538_8 COG1335 Amidases related to nicotinamidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 473.0
HFD3_k127_1211538_9 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 473.0
HFD3_k127_12129_0 protein secretion K09800 - - 0.0000000000000000000000000003532 134.0
HFD3_k127_12210_0 Domain of unknown function (DUF5117) - - - 3.281e-313 981.0
HFD3_k127_12210_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004432 519.0
HFD3_k127_12210_2 Vitamin K epoxide reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000008569 235.0
HFD3_k127_12210_3 TonB dependent receptor - - - 0.00000000000000000000000000000000002231 137.0
HFD3_k127_12210_4 iron ion homeostasis - - - 0.0000000000000000005693 98.0
HFD3_k127_1224695_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1041.0
HFD3_k127_1224695_1 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 3.92e-216 682.0
HFD3_k127_1224695_10 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000002409 242.0
HFD3_k127_1224695_11 RNA recognition motif - - - 0.0000000000000000000000000000004543 126.0
HFD3_k127_1224695_12 - - - - 0.000000000000000000000364 101.0
HFD3_k127_1224695_13 Cytochrome c - - - 0.00000000004628 72.0
HFD3_k127_1224695_14 - - - - 0.0000000005207 63.0
HFD3_k127_1224695_15 NMT1-like family K02051 - - 0.0000002482 62.0
HFD3_k127_1224695_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006174 482.0
HFD3_k127_1224695_3 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 458.0
HFD3_k127_1224695_4 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002933 412.0
HFD3_k127_1224695_5 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 400.0
HFD3_k127_1224695_6 outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 321.0
HFD3_k127_1224695_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006896 310.0
HFD3_k127_1224695_8 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008472 302.0
HFD3_k127_1224695_9 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15061,K15065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005468 281.0
HFD3_k127_12271_0 lipopolysaccharide transport K22110 - - 0.0 1399.0
HFD3_k127_12271_1 choline dehydrogenase activity - - - 2.883e-227 714.0
HFD3_k127_12271_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005725 467.0
HFD3_k127_1303041_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 8.612e-264 833.0
HFD3_k127_1303041_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 368.0
HFD3_k127_1303041_2 Transcriptional regulatory protein, C terminal K07665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 294.0
HFD3_k127_1303041_3 PFAM von Willebrand factor type A K07114,K12511 - - 0.000000000000000000000000000000000000000000000000000000000002772 220.0
HFD3_k127_1303041_4 - - - - 0.0000000000000000000000000000001845 133.0
HFD3_k127_1303041_5 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.0000000000000000000000000000008117 130.0
HFD3_k127_1303098_0 PFAM glycine cleavage T protein (aminomethyl transferase) - - - 1.162e-202 648.0
HFD3_k127_1303098_1 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005234 580.0
HFD3_k127_1303098_2 Catechol dioxygenase N terminus K03381 - 1.13.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 454.0
HFD3_k127_1303098_3 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.0000000000000000000000000000000000000000000000000000000000000000113 226.0
HFD3_k127_1317539_0 ATPase (P-type) K01535 - 3.6.3.6 0.0 1263.0
HFD3_k127_1317539_1 MacB-like periplasmic core domain - - - 1.128e-249 797.0
HFD3_k127_1317539_10 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000004013 135.0
HFD3_k127_1317539_11 Cupin domain - - - 0.00000000000000000000000000003103 119.0
HFD3_k127_1317539_12 Transcriptional - - - 0.0000000000000000000000000001003 118.0
HFD3_k127_1317539_13 - - - - 0.00000000000000000006359 96.0
HFD3_k127_1317539_14 Ferritin-like domain K04047 - - 0.000000008938 64.0
HFD3_k127_1317539_15 Protein of unknown function (DUF1634) - - - 0.00000008932 59.0
HFD3_k127_1317539_2 Pfam Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 604.0
HFD3_k127_1317539_3 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007454 434.0
HFD3_k127_1317539_4 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 290.0
HFD3_k127_1317539_5 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002073 261.0
HFD3_k127_1317539_6 Rhodanese-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009432 253.0
HFD3_k127_1317539_7 Rieske [2Fe-2S] domain K02636 - 1.10.9.1 0.0000000000000000000000000000000000000000000000000000000006921 206.0
HFD3_k127_1317539_8 transcriptional regulator PadR family - - - 0.00000000000000000000000000000000000000009195 154.0
HFD3_k127_1317539_9 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000000002594 133.0
HFD3_k127_1363161_0 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007736 581.0
HFD3_k127_1363161_1 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003743 320.0
HFD3_k127_1363161_2 domain protein K14194 - - 0.0000000000000000000000000000000000000000000000000000003021 216.0
HFD3_k127_1363161_3 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000001783 182.0
HFD3_k127_1363161_4 - - - - 0.0000000000000000000000000006599 125.0
HFD3_k127_1363161_5 - - - - 0.0000000000000000000005516 107.0
HFD3_k127_1368665_0 transmembrane transporter activity K03296,K07788,K07789 - - 0.0 1321.0
HFD3_k127_1368665_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 0.0 1173.0
HFD3_k127_1368665_10 Major Facilitator Superfamily K02575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005702 359.0
HFD3_k127_1368665_11 nitrite transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 327.0
HFD3_k127_1368665_12 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 295.0
HFD3_k127_1368665_13 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000004348 238.0
HFD3_k127_1368665_14 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000000000000000000000000000005149 225.0
HFD3_k127_1368665_15 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000000000007177 191.0
HFD3_k127_1368665_16 hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000001163 170.0
HFD3_k127_1368665_17 Protein of unknown function (DUF429) K09147 - - 0.000000000000000000000000000000000000000000009801 169.0
HFD3_k127_1368665_18 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000001371 138.0
HFD3_k127_1368665_19 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.000000000000000000000000009307 115.0
HFD3_k127_1368665_2 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.0 1038.0
HFD3_k127_1368665_20 Glyoxalase-like domain - - - 0.0000000000000000000009918 107.0
HFD3_k127_1368665_21 glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.000000000000000004018 96.0
HFD3_k127_1368665_22 Transcriptional regulatory protein, C terminal - - - 0.00000000000000001012 99.0
HFD3_k127_1368665_23 PDZ DHR GLGF domain protein - - - 0.000000000000000163 90.0
HFD3_k127_1368665_25 serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.000686 44.0
HFD3_k127_1368665_3 Glucodextranase, domain N K01178 - 3.2.1.3 2.022e-305 955.0
HFD3_k127_1368665_4 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 1.2e-230 741.0
HFD3_k127_1368665_5 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 6.336e-230 726.0
HFD3_k127_1368665_6 AAA ATPase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 524.0
HFD3_k127_1368665_7 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008952 499.0
HFD3_k127_1368665_8 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 390.0
HFD3_k127_1368665_9 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003166 350.0
HFD3_k127_1385957_0 acr, cog1565 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 347.0
HFD3_k127_1385957_1 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005054 312.0
HFD3_k127_1400942_0 RecF/RecN/SMC N terminal domain K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005325 401.0
HFD3_k127_1400942_1 MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000002837 157.0
HFD3_k127_1400942_2 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.0000000000000000000000000000005989 126.0
HFD3_k127_140760_0 Malate synthase K01638 - 2.3.3.9 3.914e-310 959.0
HFD3_k127_140760_1 Serine aminopeptidase, S33 K19311 GO:0003674,GO:0003824,GO:0005488,GO:0005504,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008289,GO:0009056,GO:0009062,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0016042,GO:0016054,GO:0016298,GO:0016787,GO:0016788,GO:0019752,GO:0031406,GO:0032787,GO:0033293,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0071214,GO:0071467,GO:0071468,GO:0071704,GO:0072329,GO:0104004,GO:1901575 - 0.0000000000000000000000000000000000000001363 162.0
HFD3_k127_140760_2 Rubrerythrin K03594 - 1.16.3.1 0.00000000000000000000000000000000000429 144.0
HFD3_k127_140760_3 Haem-degrading K11477 - - 0.00000000000000000000000000000000001363 139.0
HFD3_k127_140760_4 beta-propeller repeat - - - 0.0000000000000000000000000001417 130.0
HFD3_k127_140760_5 PBP superfamily domain - - - 0.00000001557 57.0
HFD3_k127_1424782_0 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002898 412.0
HFD3_k127_1424782_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 327.0
HFD3_k127_1424782_2 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005923 284.0
HFD3_k127_1424782_3 ABC nitrate sulphonate bicarbonate family transporter, ATPase subunit K02049 - - 0.000000000000000000000000000000000009812 141.0
HFD3_k127_1424782_4 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000006426 97.0
HFD3_k127_1440472_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 617.0
HFD3_k127_1440472_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004562 522.0
HFD3_k127_1440472_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 347.0
HFD3_k127_1440472_11 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 325.0
HFD3_k127_1440472_12 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000000000293 217.0
HFD3_k127_1440472_13 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000231 201.0
HFD3_k127_1440472_14 - - - - 0.0000000000000000000000000000000000000000000000000000002424 208.0
HFD3_k127_1440472_15 domain protein K14194 - - 0.00000000000000000000000000000000000000000000000000003547 212.0
HFD3_k127_1440472_16 Conserved hypothetical protein 95 - - - 0.000000000000000000000000000000000000000000000001345 181.0
HFD3_k127_1440472_17 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000002676 168.0
HFD3_k127_1440472_18 - - - - 0.0000000000000000000000000000000002816 139.0
HFD3_k127_1440472_19 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000008005 135.0
HFD3_k127_1440472_2 UDP-N-acetylmuramate-L-alanine ligase activity K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007245 521.0
HFD3_k127_1440472_20 Tetratricopeptide repeat - - - 0.000000000000000000000000000002326 136.0
HFD3_k127_1440472_21 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000191 116.0
HFD3_k127_1440472_22 - - - - 0.00000000000000000000004431 114.0
HFD3_k127_1440472_23 Cell division protein FtsQ K03589 - - 0.0000000000000000000002646 107.0
HFD3_k127_1440472_24 - - - - 0.0000000000000000005111 93.0
HFD3_k127_1440472_25 - - - - 0.000000000000000703 83.0
HFD3_k127_1440472_26 - - - - 0.000000000000002724 89.0
HFD3_k127_1440472_27 metal cluster binding - - - 0.000000000000002746 83.0
HFD3_k127_1440472_28 - - - - 0.00000000000001291 80.0
HFD3_k127_1440472_29 - - - - 0.0001347 53.0
HFD3_k127_1440472_3 PFAM aminotransferase, class I K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 494.0
HFD3_k127_1440472_4 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000442 459.0
HFD3_k127_1440472_5 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003937 416.0
HFD3_k127_1440472_6 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004754 380.0
HFD3_k127_1440472_7 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003761 380.0
HFD3_k127_1440472_8 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003535 364.0
HFD3_k127_1440472_9 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008274 346.0
HFD3_k127_1454679_0 Dehydrogenase K00117 - 1.1.5.2 1.258e-276 863.0
HFD3_k127_1454679_1 alginic acid biosynthetic process K01729 - 4.2.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 607.0
HFD3_k127_1454679_10 Cupin 2, conserved barrel domain protein - - - 0.0000000006746 67.0
HFD3_k127_1454679_11 Short C-terminal domain - - - 0.0000003018 56.0
HFD3_k127_1454679_12 lactoylglutathione lyase activity - - - 0.000006607 51.0
HFD3_k127_1454679_13 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0001114 54.0
HFD3_k127_1454679_2 HupE / UreJ protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 298.0
HFD3_k127_1454679_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000001033 270.0
HFD3_k127_1454679_4 Thiopurine S-methyltransferase (TPMT) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000104 257.0
HFD3_k127_1454679_5 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000002428 191.0
HFD3_k127_1454679_6 - - - - 0.000000000000000000000000000000000000000000001537 183.0
HFD3_k127_1454679_7 - - - - 0.000000000000000000000000000001194 133.0
HFD3_k127_1454679_8 - - - - 0.000000000000000015 85.0
HFD3_k127_152437_0 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 576.0
HFD3_k127_152437_1 PFAM Cytochrome b b6 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007459 416.0
HFD3_k127_152437_10 Protein of unknown function (DUF420) - - - 0.000000000000000000000000000000000000005305 154.0
HFD3_k127_152437_11 protein SCO1 SenC K07152 - - 0.000000000000000000000000000000000003217 154.0
HFD3_k127_152437_12 deoxyhypusine monooxygenase activity - - - 0.00000000005021 74.0
HFD3_k127_152437_2 Cytochrome b(C-terminal)/b6/petD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005194 404.0
HFD3_k127_152437_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 351.0
HFD3_k127_152437_4 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002273 265.0
HFD3_k127_152437_5 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000001317 266.0
HFD3_k127_152437_6 Cytochrome oxidase assembly protein K02259 - - 0.00000000000000000000000000000000000000000000000000000000000001187 227.0
HFD3_k127_152437_7 Rieske [2Fe-2S] domain K02636 - 1.10.9.1 0.000000000000000000000000000000000000000000000000000000000001656 216.0
HFD3_k127_152437_8 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000872 193.0
HFD3_k127_152437_9 Polysaccharide lyase family 4, domain II - - - 0.000000000000000000000000000000000000000000001191 174.0
HFD3_k127_1534176_0 PQQ-like domain K00114 - 1.1.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 506.0
HFD3_k127_1534176_1 gluconolactonase activity K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004902 343.0
HFD3_k127_1534176_10 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000006032 111.0
HFD3_k127_1534176_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004223 284.0
HFD3_k127_1534176_3 PFAM Acetyltransferase (GNAT) family K06976 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003464 251.0
HFD3_k127_1534176_4 response to abiotic stimulus K06867 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007125 259.0
HFD3_k127_1534176_5 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000000000000000000000000000000000004431 233.0
HFD3_k127_1534176_6 Protein of unknown function (DUF1552) - - - 0.0000000000000000000000000000000000000000000000000000000000000009665 226.0
HFD3_k127_1534176_7 - - - - 0.000000000000000000000000000000000000000001028 169.0
HFD3_k127_1534176_8 - - - - 0.000000000000000000000000000000000000000021 157.0
HFD3_k127_1534176_9 Membrane transport protein K07088 - - 0.0000000000000000000000000000000001885 143.0
HFD3_k127_1561620_0 PFAM type II secretion system protein E K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003925 558.0
HFD3_k127_1561620_1 PFAM type II secretion system protein E K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009323 516.0
HFD3_k127_1561620_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003714 472.0
HFD3_k127_1561620_3 Belongs to the aldehyde dehydrogenase family K00135,K22445 - 1.2.1.16,1.2.1.20,1.2.1.79,1.2.99.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005364 409.0
HFD3_k127_1561620_4 Belongs to the Dps family K04047 - - 0.0000000000000000000000000000000000000000000004847 174.0
HFD3_k127_1561620_5 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000006466 91.0
HFD3_k127_1576537_0 amino acid - - - 1.11e-244 772.0
HFD3_k127_1576537_1 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006812 272.0
HFD3_k127_1576537_2 PFAM NAD-dependent epimerase dehydratase K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000001439 249.0
HFD3_k127_1576537_3 - - - - 0.0000000000000000000000000000000000000000001125 164.0
HFD3_k127_1576537_4 Protein conserved in bacteria - - - 0.000000000000000000000000000989 118.0
HFD3_k127_1576537_5 - - - - 0.00003046 49.0
HFD3_k127_1588879_0 DNA topological change K03168 - 5.99.1.2 1.226e-217 700.0
HFD3_k127_1588879_1 ThiF family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007861 480.0
HFD3_k127_1588879_2 Protein of unknown function (DUF1552) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 375.0
HFD3_k127_1588879_3 Domain of unknown function (DUF374) K09778 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 315.0
HFD3_k127_1588879_4 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001085 284.0
HFD3_k127_1588879_5 Ankyrin repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002538 294.0
HFD3_k127_1588879_6 HAD-hyrolase-like - - - 0.00000000000000000000000000000000000000000006488 168.0
HFD3_k127_1588879_7 PFAM TPR repeat-containing protein - - - 0.000000000000000000000000000000000000000006285 170.0
HFD3_k127_1588879_8 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000002696 142.0
HFD3_k127_1597748_0 Periplasmic binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007618 605.0
HFD3_k127_1597748_1 Phage integrase, N-terminal SAM-like domain K04763 - - 0.000000000000000000000000000000000000000001083 162.0
HFD3_k127_1611154_0 Pantothenic acid kinase K00867 GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 403.0
HFD3_k127_1611154_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 377.0
HFD3_k127_1611154_11 PFAM pentapeptide repeat protein - - - 0.00000000000001861 78.0
HFD3_k127_1611154_2 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004207 354.0
HFD3_k127_1611154_3 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008892 325.0
HFD3_k127_1611154_4 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 294.0
HFD3_k127_1611154_5 arginyltransferase activity K21420 GO:0003674,GO:0003824,GO:0004057,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016598,GO:0016740,GO:0016746,GO:0016755,GO:0019538,GO:0019941,GO:0030163,GO:0036211,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 2.3.2.29 0.00000000000000000000000000000000000000000000000000000000000000009654 232.0
HFD3_k127_1611154_6 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000002052 196.0
HFD3_k127_1611154_7 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000008231 173.0
HFD3_k127_1611154_8 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000000000000000002546 149.0
HFD3_k127_1611154_9 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000006092 127.0
HFD3_k127_1619432_0 imidazolonepropionase activity - - - 0.0000000000000000000000000000000000000000000000000002417 203.0
HFD3_k127_161945_0 transposition - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 510.0
HFD3_k127_161945_1 PFAM RNA-directed DNA polymerase (Reverse transcriptase) K00986 - 2.7.7.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009406 423.0
HFD3_k127_161945_2 DNA primase activity K02316,K17680 - 3.6.4.12 0.00000000000000000000000000000000000000002286 163.0
HFD3_k127_1624479_0 Thymidylate synthase complementing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 363.0
HFD3_k127_1624479_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008958 336.0
HFD3_k127_1624479_2 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000001808 150.0
HFD3_k127_1624479_3 Tetratricopeptide repeat - - - 0.00000000000000000000002633 106.0
HFD3_k127_1624479_4 - - - - 0.000000000000000001024 91.0
HFD3_k127_1629171_0 competence protein COMEC K02238 - - 4.124e-194 619.0
HFD3_k127_1629171_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005338 576.0
HFD3_k127_1629171_10 domain, Protein - - - 0.00007111 51.0
HFD3_k127_1629171_2 NADH ubiquinone oxidoreductase, 20 Kd subunit K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004294 280.0
HFD3_k127_1629171_3 TIGRFAM molybdenum cofactor synthesis K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000139 291.0
HFD3_k127_1629171_4 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004575 275.0
HFD3_k127_1629171_5 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000001983 186.0
HFD3_k127_1629171_6 NnrS protein - - - 0.00000000000000000000000000000000000000000001156 179.0
HFD3_k127_1629171_7 TIGRFAM molybdenum cofactor synthesis - - - 0.000000000000000000000000000000000000000007052 160.0
HFD3_k127_1629171_8 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K00330 - 1.6.5.3 0.0000000000000000000000000000000000006604 146.0
HFD3_k127_1642412_0 amine oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 406.0
HFD3_k127_1642412_1 - - - - 0.0000000000000000000000000000000000000000000000000006926 191.0
HFD3_k127_1642412_2 Universal stress protein family - - - 0.000000000000000002609 93.0
HFD3_k127_1642412_3 thiolester hydrolase activity K06889 - - 0.00000000000001056 84.0
HFD3_k127_1642412_5 Protein of unknown function (DUF3096) - - - 0.00000002373 60.0
HFD3_k127_1643180_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 1.923e-309 961.0
HFD3_k127_1643180_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 580.0
HFD3_k127_1643180_2 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 380.0
HFD3_k127_1643180_3 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 372.0
HFD3_k127_1643180_4 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 305.0
HFD3_k127_1645235_0 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000001333 209.0
HFD3_k127_1645235_1 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000000458 199.0
HFD3_k127_1647398_0 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009781 373.0
HFD3_k127_1647398_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000004526 242.0
HFD3_k127_1678610_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 1.019e-218 711.0
HFD3_k127_1678610_1 PFAM Protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005322 448.0
HFD3_k127_1678610_2 Transposase - - - 0.000000000000000000000000000000000504 136.0
HFD3_k127_1678610_3 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000006669 130.0
HFD3_k127_1678610_4 Sigma-54 interaction domain - - - 0.00000000000000000000000000001801 123.0
HFD3_k127_1678610_6 - - - - 0.0000000000000000003013 91.0
HFD3_k127_1678610_7 - - - - 0.0000000000000381 76.0
HFD3_k127_1678610_8 Formamidopyrimidine-DNA glycosylase N-terminal domain K10563 - 3.2.2.23,4.2.99.18 0.000000000001337 74.0
HFD3_k127_1678610_9 Alpha/beta hydrolase family K01259 - 3.4.11.5 0.0008381 44.0
HFD3_k127_1687487_0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S K00311 - 1.5.5.1 1.176e-199 635.0
HFD3_k127_1687487_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008616 585.0
HFD3_k127_1687487_2 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 407.0
HFD3_k127_1687487_3 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 351.0
HFD3_k127_1687487_4 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000004316 121.0
HFD3_k127_1687487_5 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000005343 123.0
HFD3_k127_1687487_6 Ribosomal L32p protein family K02911 - - 0.000000000000000000000122 100.0
HFD3_k127_1687487_7 Uncharacterized conserved protein (DUF2075) - - - 0.000000000000005704 75.0
HFD3_k127_1687487_8 SdrD B-like domain - - - 0.0000000007233 72.0
HFD3_k127_1687487_9 Tetratricopeptide repeat protein - - - 0.000000005845 66.0
HFD3_k127_172548_0 Succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1090.0
HFD3_k127_172548_1 Dienelactone hydrolase family - - - 1.527e-255 806.0
HFD3_k127_172548_2 Myo-inositol-1-phosphate synthase, GAPDH domain protein K01858 - 5.5.1.4 2.231e-213 669.0
HFD3_k127_172548_3 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 413.0
HFD3_k127_172548_4 fumarate reductase) cytochrome b subunit K00241 - - 0.0000000000000000000000000000000000000000000000000000000000000000003909 235.0
HFD3_k127_172548_5 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins K03790 GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008999,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.3.1.128 0.0000000000000000000000000000000000000000000000001872 181.0
HFD3_k127_172548_6 hydrolase K07025 - - 0.000000000000000000000000000000000000004749 154.0
HFD3_k127_1790403_0 Zinc dependent phospholipase C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 453.0
HFD3_k127_1790403_1 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 361.0
HFD3_k127_1790403_2 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002321 300.0
HFD3_k127_1790403_3 von Willebrand factor (vWF) type A domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007267 266.0
HFD3_k127_1790403_4 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000358 171.0
HFD3_k127_1790403_5 FtsX-like permease family - - - 0.00000000000000000000000000001601 123.0
HFD3_k127_1790403_7 GDSL-like Lipase/Acylhydrolase - - - 0.00000000000000000000000006968 115.0
HFD3_k127_1790403_8 peptidyl-tyrosine sulfation - - - 0.00000000004076 74.0
HFD3_k127_1793803_0 PQQ-like domain K00114 - 1.1.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 530.0
HFD3_k127_1793803_1 translation initiation inhibitor, yjgF family K04782 - 4.2.99.21 0.00000000000000000000000000000000000000000000000000001427 196.0
HFD3_k127_1793803_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000001448 88.0
HFD3_k127_1854365_0 PQQ-like domain K00117 - 1.1.5.2 1.529e-196 632.0
HFD3_k127_1854365_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 442.0
HFD3_k127_1854365_10 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000002664 118.0
HFD3_k127_1854365_2 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 361.0
HFD3_k127_1854365_4 DNA topological change K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001024 299.0
HFD3_k127_1854365_5 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000001456 243.0
HFD3_k127_1854365_6 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000008337 199.0
HFD3_k127_1854365_7 - - - - 0.0000000000000000000000000000000000000000005819 165.0
HFD3_k127_1854365_8 - - - - 0.00000000000000000000000000000000000000000721 160.0
HFD3_k127_1854365_9 Cytochrome C' - - - 0.0000000000000000000000000000000004376 138.0
HFD3_k127_1862226_0 Belongs to the peptidase M16 family K07263 - - 0.0 1026.0
HFD3_k127_1862226_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 356.0
HFD3_k127_1862226_2 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001054 283.0
HFD3_k127_1862226_3 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000003095 179.0
HFD3_k127_1862226_4 - - - - 0.00000000000000000000000000004459 121.0
HFD3_k127_1862226_5 - - - - 0.00000000000003811 78.0
HFD3_k127_1862226_6 Glyoxalase bleomycin resistance protein dioxygenase K01759 - 4.4.1.5 0.000000001501 65.0
HFD3_k127_1867388_0 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005781 471.0
HFD3_k127_1867388_1 Lysin motif K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 416.0
HFD3_k127_1867388_10 HEAT repeats - - - 0.000000000000000000000001579 115.0
HFD3_k127_1867388_11 - - - - 0.0000000000000006759 85.0
HFD3_k127_1867388_12 - - - - 0.00000000001768 76.0
HFD3_k127_1867388_13 - - - - 0.000000008918 61.0
HFD3_k127_1867388_14 OmpA family - - - 0.000002557 59.0
HFD3_k127_1867388_2 5'-3' exonuclease, N-terminal resolvase-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 396.0
HFD3_k127_1867388_3 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008961 408.0
HFD3_k127_1867388_4 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 293.0
HFD3_k127_1867388_5 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008468 284.0
HFD3_k127_1867388_6 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007026 295.0
HFD3_k127_1867388_7 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000000000000000000008 194.0
HFD3_k127_1867388_8 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000001026 120.0
HFD3_k127_1867388_9 - - - - 0.0000000000000000000000001706 119.0
HFD3_k127_1872107_0 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000000000000000001876 178.0
HFD3_k127_1872107_1 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000007567 176.0
HFD3_k127_1872107_2 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.000000000000000000000000000000000000000000005904 169.0
HFD3_k127_1872107_3 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000001337 65.0
HFD3_k127_1872107_4 PBS lyase K22221 - - 0.0000001125 60.0
HFD3_k127_187486_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 1.139e-209 682.0
HFD3_k127_187486_1 Multicopper oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004994 471.0
HFD3_k127_187486_2 Clostripain family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 447.0
HFD3_k127_187486_3 CHAT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006557 424.0
HFD3_k127_187486_4 - - - - 0.0001357 50.0
HFD3_k127_187486_5 GDSL-like Lipase/Acylhydrolase family - - - 0.0002243 51.0
HFD3_k127_187486_6 InterPro IPR007367 - - - 0.0006811 46.0
HFD3_k127_189951_0 Xylose isomerase-like TIM barrel K01816 - 5.3.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005738 391.0
HFD3_k127_189951_1 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000703 379.0
HFD3_k127_189951_2 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000022 248.0
HFD3_k127_1911355_0 DinB superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002944 461.0
HFD3_k127_1911355_1 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 401.0
HFD3_k127_1911355_2 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008773 345.0
HFD3_k127_1911355_3 PAP2 superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 339.0
HFD3_k127_1911355_4 TonB-dependent Receptor Plug K02014 - - 0.000000000000000000000000000000000007972 139.0
HFD3_k127_1911355_5 - - - - 0.00000000000000000000000000000000007206 137.0
HFD3_k127_1917827_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 8.23e-273 849.0
HFD3_k127_1917827_1 Dehydrogenase K00117 - 1.1.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 615.0
HFD3_k127_1917827_10 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000003785 179.0
HFD3_k127_1917827_11 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000228 134.0
HFD3_k127_1917827_12 - - - - 0.000000000000000000000000000000002584 132.0
HFD3_k127_1917827_13 domain protein - - - 0.000000000000000000000000000000006388 147.0
HFD3_k127_1917827_14 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000191 121.0
HFD3_k127_1917827_15 Protein of unknown function (DUF3311) - - - 0.0000000000000000000002716 100.0
HFD3_k127_1917827_16 - - - - 0.00000000000000000003596 94.0
HFD3_k127_1917827_19 Carboxypeptidase regulatory-like domain - - - 0.0000000000000826 85.0
HFD3_k127_1917827_2 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 437.0
HFD3_k127_1917827_20 - - - - 0.00000000000404 71.0
HFD3_k127_1917827_22 'TIGRFAM RNA polymerase sigma factor, sigma-70 family' K03088 - - 0.00003569 48.0
HFD3_k127_1917827_23 Antibiotic biosynthesis monooxygenase K11530 - 5.3.1.32 0.0001808 48.0
HFD3_k127_1917827_3 tRNA synthetases class I (M) K01874 - 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009932 439.0
HFD3_k127_1917827_4 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004998 419.0
HFD3_k127_1917827_5 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006572 382.0
HFD3_k127_1917827_6 beta-galactosidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009139 308.0
HFD3_k127_1917827_7 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000006492 262.0
HFD3_k127_1917827_8 RNA polymerase sigma factor - - - 0.000000000000000000000000000000000000000000000000000000000001898 215.0
HFD3_k127_1917827_9 Intracellular protease, PfpI K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000889 180.0
HFD3_k127_1933235_0 PQQ-like domain K00117 - 1.1.5.2 2.465e-196 632.0
HFD3_k127_1933235_1 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 590.0
HFD3_k127_1933235_10 MobA-related protein K07141,K19190 - 1.1.1.328,2.7.7.76 0.000000000000000000000000000000001299 137.0
HFD3_k127_1933235_11 Antibiotic biosynthesis monooxygenase K11530 - 5.3.1.32 0.0000000000000000009543 91.0
HFD3_k127_1933235_12 Acetyltransferase K03789 - 2.3.1.128 0.00000003376 61.0
HFD3_k127_1933235_2 Domain of unknown function (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009641 492.0
HFD3_k127_1933235_3 PQQ-like domain K17760 - 1.1.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 458.0
HFD3_k127_1933235_4 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000005464 241.0
HFD3_k127_1933235_5 MOSC domain - - - 0.00000000000000000000000000000000000000000000000000000000000002132 218.0
HFD3_k127_1933235_6 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000000000000000000000000164 202.0
HFD3_k127_1933235_7 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.0000000000000000000000000000000000000000000000001885 185.0
HFD3_k127_1933235_8 Phosphatidylethanolamine-binding protein - - - 0.0000000000000000000000000000000000000000018 165.0
HFD3_k127_1933235_9 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.00000000000000000000000000000000001227 137.0
HFD3_k127_1946807_0 Aldehyde dehydrogenase family K00141,K21802 - 1.2.1.28,1.2.1.67 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 588.0
HFD3_k127_1946807_1 two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 528.0
HFD3_k127_1946807_10 phospho-N-acetylmuramoyl-pentapeptide-transferase activity K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001486 287.0
HFD3_k127_1946807_11 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001051 250.0
HFD3_k127_1946807_12 Methyltransferase domain - - - 0.000000000000000000000000000000000000001112 152.0
HFD3_k127_1946807_13 Maltose acetyltransferase K00661 - 2.3.1.79 0.0000000000000000000003434 105.0
HFD3_k127_1946807_2 Two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000561 463.0
HFD3_k127_1946807_3 PFAM Type II secretion system F domain K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000885 446.0
HFD3_k127_1946807_4 Flavin containing amine oxidoreductase K00231,K01854 - 1.3.3.15,1.3.3.4,5.4.99.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 432.0
HFD3_k127_1946807_5 Membrane protein involved in the export of O-antigen and teichoic acid K03328 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009951 413.0
HFD3_k127_1946807_6 signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002807 397.0
HFD3_k127_1946807_7 Belongs to the DegT DnrJ EryC1 family K02805,K20429 - 2.6.1.33,2.6.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 372.0
HFD3_k127_1946807_8 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 342.0
HFD3_k127_1946807_9 phosphorelay sensor kinase activity K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 322.0
HFD3_k127_1968820_0 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 6.581e-200 658.0
HFD3_k127_1968820_1 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000008329 194.0
HFD3_k127_1968820_2 YCII-related domain - - - 0.0000000000000000000000000000000000000000000000000985 180.0
HFD3_k127_1982682_0 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 1.288e-263 824.0
HFD3_k127_1982682_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 5.036e-206 649.0
HFD3_k127_1982682_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 483.0
HFD3_k127_1982682_3 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 448.0
HFD3_k127_1982682_4 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004207 391.0
HFD3_k127_1982682_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000002224 182.0
HFD3_k127_1982682_7 Transcriptional regulator K07727 - - 0.00000000000000000000000006876 108.0
HFD3_k127_1982682_8 COG0440 Acetolactate synthase, small (regulatory) subunit K01653 - 2.2.1.6 0.0000000000005094 74.0
HFD3_k127_1996029_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 5.265e-295 931.0
HFD3_k127_1996029_1 lipolytic protein G-D-S-L family - - - 1.972e-239 748.0
HFD3_k127_1996029_10 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 340.0
HFD3_k127_1996029_11 Pfam Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006384 334.0
HFD3_k127_1996029_12 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 324.0
HFD3_k127_1996029_13 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 298.0
HFD3_k127_1996029_14 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007135 299.0
HFD3_k127_1996029_15 Ku70/Ku80 beta-barrel domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003617 263.0
HFD3_k127_1996029_16 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000002274 255.0
HFD3_k127_1996029_17 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001055 251.0
HFD3_k127_1996029_18 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001644 245.0
HFD3_k127_1996029_19 Belongs to the PdxA family K00097 - 1.1.1.262 0.00000000000000000000000000000000000000000000000000000000000000000002159 244.0
HFD3_k127_1996029_2 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006073 488.0
HFD3_k127_1996029_20 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000002242 228.0
HFD3_k127_1996029_21 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000246 221.0
HFD3_k127_1996029_22 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000006897 215.0
HFD3_k127_1996029_23 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000007674 220.0
HFD3_k127_1996029_24 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000001507 214.0
HFD3_k127_1996029_25 protein conserved in cyanobacteria - - - 0.0000000000000000000000000000000000000000000000000000000003424 212.0
HFD3_k127_1996029_26 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000000000000007492 207.0
HFD3_k127_1996029_27 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042886,GO:0042887,GO:0043953,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.00000000000000000000000000000000000000000000000000000002041 207.0
HFD3_k127_1996029_28 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000000000000007348 201.0
HFD3_k127_1996029_29 SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000001263 195.0
HFD3_k127_1996029_3 aminoacyl-tRNA synthetase K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 440.0
HFD3_k127_1996029_30 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000000000004583 194.0
HFD3_k127_1996029_31 Tetrapyrrole (Corrin/Porphyrin) Methylases K01719,K02302,K02303,K13542 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.0000000000000000000000000000000000000000000000001551 187.0
HFD3_k127_1996029_32 PFAM cytochrome c assembly protein - - - 0.000000000000000000000000000000000000000000000007571 183.0
HFD3_k127_1996029_33 CoA binding domain K06929 - - 0.0000000000000000000000000000000000000000000001218 172.0
HFD3_k127_1996029_34 DNA polymerase III, delta' K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000006126 179.0
HFD3_k127_1996029_35 phosphorelay sensor kinase activity K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000001704 184.0
HFD3_k127_1996029_36 Peptidase family M50 K06402 - - 0.0000000000000000000000000000000000000000005734 168.0
HFD3_k127_1996029_37 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000003503 159.0
HFD3_k127_1996029_38 Signal peptidase (SPase) II - - - 0.0000000000000000000000000000000000733 140.0
HFD3_k127_1996029_39 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000007946 134.0
HFD3_k127_1996029_4 LytB protein K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 429.0
HFD3_k127_1996029_40 Tetratricopeptide repeat - - - 0.000000000000000000000000000004952 134.0
HFD3_k127_1996029_41 Hfq protein - - - 0.000000000000000000000000004096 115.0
HFD3_k127_1996029_42 TIGRFAM Addiction module toxin, RelE StbE K19092 - - 0.00000000000000000000000101 106.0
HFD3_k127_1996029_43 - - - - 0.00000000000000000000008488 103.0
HFD3_k127_1996029_44 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000000007857 92.0
HFD3_k127_1996029_45 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117,K03646 - - 0.00000000000000139 81.0
HFD3_k127_1996029_46 Belongs to the UPF0235 family K09131 - - 0.000000000000281 73.0
HFD3_k127_1996029_47 - - - - 0.000008527 55.0
HFD3_k127_1996029_5 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003838 433.0
HFD3_k127_1996029_6 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 425.0
HFD3_k127_1996029_7 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003372 406.0
HFD3_k127_1996029_8 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007225 357.0
HFD3_k127_1996029_9 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 351.0
HFD3_k127_2011214_0 Protein of unknown function, DUF255 K06888 - - 2.37e-219 700.0
HFD3_k127_2011214_1 R3H domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006517 559.0
HFD3_k127_2034287_0 - - - - 3.462e-320 994.0
HFD3_k127_2034287_1 DNA topological change K03168 - 5.99.1.2 4.894e-243 774.0
HFD3_k127_2034287_10 oligosaccharyl transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 364.0
HFD3_k127_2034287_11 TIGRFAM PQQ-dependent dehydrogenase, methanol ethanol family K00114 - 1.1.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005215 315.0
HFD3_k127_2034287_12 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001657 293.0
HFD3_k127_2034287_13 Ankyrin repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009613 280.0
HFD3_k127_2034287_14 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001009 259.0
HFD3_k127_2034287_15 response to heat K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008449 252.0
HFD3_k127_2034287_16 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000009132 224.0
HFD3_k127_2034287_17 Type II secretion system K12510 - - 0.000000000000000000000000000000000000000000000000000000000598 213.0
HFD3_k127_2034287_18 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000005472 205.0
HFD3_k127_2034287_19 Type II secretion system K12511 - - 0.000000000000000000000000000000000000000000000000000001473 202.0
HFD3_k127_2034287_2 PFAM type II secretion system protein E K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004517 524.0
HFD3_k127_2034287_20 PFAM SAF domain K02279 - - 0.000000000000000000000000000000000000000000000000000001653 203.0
HFD3_k127_2034287_21 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000006574 191.0
HFD3_k127_2034287_22 COG3258 Cytochrome c K19713 - 1.8.2.2 0.0000000000000000000000000000000000000000000000000004581 197.0
HFD3_k127_2034287_23 decarboxylase K01607 - 4.1.1.44 0.00000000000000000000000000000000000000000000000002103 188.0
HFD3_k127_2034287_24 Histidine kinase - - - 0.00000000000000000000000000000000000000000000001672 187.0
HFD3_k127_2034287_25 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000003233 177.0
HFD3_k127_2034287_26 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000000000000000007101 179.0
HFD3_k127_2034287_27 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000006095 176.0
HFD3_k127_2034287_28 ribonuclease BN K07058 - - 0.00000000000000000000000000000000000000000005938 170.0
HFD3_k127_2034287_29 Transcription factor zinc-finger - - - 0.0000000000000000000000000000000000009202 148.0
HFD3_k127_2034287_3 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006567 521.0
HFD3_k127_2034287_30 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000008085 138.0
HFD3_k127_2034287_31 AAA domain K02282 - - 0.00000000000000000000000000005964 130.0
HFD3_k127_2034287_32 Carboxylesterase family - - - 0.0000000000000000000000001174 122.0
HFD3_k127_2034287_33 Putative Flp pilus-assembly TadE/G-like - - - 0.000000000000000000000003252 115.0
HFD3_k127_2034287_34 - - - - 0.000000000000000000001301 101.0
HFD3_k127_2034287_35 - - - - 0.00000000000000001036 91.0
HFD3_k127_2034287_36 TadE-like protein - - - 0.000000002709 64.0
HFD3_k127_2034287_37 TadE-like protein - - - 0.00000121 56.0
HFD3_k127_2034287_4 SMP-30/Gluconolaconase/LRE-like region K01053,K13735 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 440.0
HFD3_k127_2034287_5 PFAM filamentation induced by cAMP protein Fic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 432.0
HFD3_k127_2034287_6 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 415.0
HFD3_k127_2034287_7 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 395.0
HFD3_k127_2034287_8 Belongs to the GSP D family K02280 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 372.0
HFD3_k127_2034287_9 Sugar (and other) transporter K08195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 369.0
HFD3_k127_2055127_0 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 605.0
HFD3_k127_2055127_1 Replicative DNA helicase K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004088 476.0
HFD3_k127_2055127_10 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000000000002536 121.0
HFD3_k127_2055127_11 methyltransferase - - - 0.0000000000000000001061 98.0
HFD3_k127_2055127_12 Acetyltransferase (GNAT) domain - - - 0.00000000000003864 79.0
HFD3_k127_2055127_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004345 465.0
HFD3_k127_2055127_3 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 426.0
HFD3_k127_2055127_4 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000000000493 197.0
HFD3_k127_2055127_5 GHMP kinases N terminal domain K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000002022 184.0
HFD3_k127_2055127_6 binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000000000003365 156.0
HFD3_k127_2055127_7 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000007646 160.0
HFD3_k127_2055127_8 PFAM glycosyl transferase family 39 - - - 0.000000000000000000000000000000008251 145.0
HFD3_k127_2055127_9 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000000000001644 125.0
HFD3_k127_206778_0 Belongs to the SOS response-associated peptidase family - - - 0.00000000000000000000000000000000000000000003412 171.0
HFD3_k127_206778_1 transport - - - 0.000000000000000000000000000000000000008164 164.0
HFD3_k127_206778_2 PFAM RNA recognition motif - - - 0.00000000000000000000000000001574 121.0
HFD3_k127_2074361_0 Lipase maturation factor - - - 0.00000000000000000000000000000000000000000000000000000000000000395 233.0
HFD3_k127_2074361_1 response to copper ion K01187,K16915 - 3.2.1.20 0.0000000000000000000000000000000000000000000000000004364 197.0
HFD3_k127_2074361_2 Protein of unknown function (DUF1572) - - - 0.000000000000000000000000000000000000000000002812 169.0
HFD3_k127_2074361_3 Predicted membrane protein (DUF2306) - - - 0.00000000000000000000000000000000000000104 158.0
HFD3_k127_2074361_4 - - - - 0.000000000000000000000000000000000000002792 167.0
HFD3_k127_2074361_5 PFAM Copper type II ascorbate-dependent monooxygenase, C-terminal domain - - - 0.0000000000000000000000000000000001837 147.0
HFD3_k127_2081623_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 1.014e-218 692.0
HFD3_k127_2081623_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 558.0
HFD3_k127_2081623_10 Putative neutral zinc metallopeptidase K07054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005004 344.0
HFD3_k127_2081623_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008945 342.0
HFD3_k127_2081623_12 TIGRFAM PQQ-dependent dehydrogenase, methanol ethanol family K00114 - 1.1.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 349.0
HFD3_k127_2081623_13 ABC-type uncharacterized transport system K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 344.0
HFD3_k127_2081623_14 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004289 339.0
HFD3_k127_2081623_15 formate dehydrogenase (NAD+) activity K00336,K18006 - 1.12.1.2,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000958 333.0
HFD3_k127_2081623_16 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007631 333.0
HFD3_k127_2081623_17 AIR carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007251 308.0
HFD3_k127_2081623_18 PFAM monooxygenase FAD-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 304.0
HFD3_k127_2081623_19 Protein of unknown function (DUF2914) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 299.0
HFD3_k127_2081623_2 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 561.0
HFD3_k127_2081623_20 Metallopeptidase family M24 K01262 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0030145,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006957 304.0
HFD3_k127_2081623_21 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001997 279.0
HFD3_k127_2081623_22 Polysaccharide biosynthesis protein K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000007166 241.0
HFD3_k127_2081623_23 rRNA (uridine-N3-)-methyltransferase activity K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000000000005975 235.0
HFD3_k127_2081623_24 von Willebrand factor (vWF) type A domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000103 235.0
HFD3_k127_2081623_25 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000001641 231.0
HFD3_k127_2081623_26 Rhodanese-like domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000005424 229.0
HFD3_k127_2081623_27 Orotidine 5'-phosphate decarboxylase / HUMPS family K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000006908 217.0
HFD3_k127_2081623_28 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000001054 218.0
HFD3_k127_2081623_29 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000007817 197.0
HFD3_k127_2081623_3 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008042 522.0
HFD3_k127_2081623_30 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000001156 184.0
HFD3_k127_2081623_31 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000000000000009583 173.0
HFD3_k127_2081623_32 C4-type zinc ribbon domain K07164 - - 0.00000000000000000000000000000000000001831 154.0
HFD3_k127_2081623_33 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000001571 149.0
HFD3_k127_2081623_34 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000002772 111.0
HFD3_k127_2081623_35 Tetratricopeptide repeat - - - 0.0000000000000000000000006271 117.0
HFD3_k127_2081623_36 Sigma-70, region 4 K03088 - - 0.000000000000000000106 96.0
HFD3_k127_2081623_37 Domain of unknown function (DUF4340) - - - 0.0000000000000004555 91.0
HFD3_k127_2081623_39 Dehydrogenase K00114 - 1.1.2.8 0.0000001996 56.0
HFD3_k127_2081623_4 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 480.0
HFD3_k127_2081623_40 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0003061 48.0
HFD3_k127_2081623_41 Recombinase zinc beta ribbon domain - - - 0.0007844 42.0
HFD3_k127_2081623_5 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003053 467.0
HFD3_k127_2081623_6 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003431 454.0
HFD3_k127_2081623_7 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 368.0
HFD3_k127_2081623_8 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006364 351.0
HFD3_k127_2081623_9 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007768 346.0
HFD3_k127_2138524_0 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 601.0
HFD3_k127_2138524_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 479.0
HFD3_k127_2138524_2 epimerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005732 432.0
HFD3_k127_2138524_3 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000598 202.0
HFD3_k127_2138524_4 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000005459 179.0
HFD3_k127_2138524_5 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549,K22363 - 2.1.1.14,4.4.1.23 0.000000000000000000000000000000000000000000004377 179.0
HFD3_k127_2138524_6 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000004936 150.0
HFD3_k127_2138524_7 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000008512 134.0
HFD3_k127_2138524_8 diguanylate cyclase K02488 - 2.7.7.65 0.0000000000000000000000002267 121.0
HFD3_k127_2138524_9 EcsC protein family - - - 0.00000007122 64.0
HFD3_k127_2148599_0 Transketolase, pyrimidine binding domain K21417 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 413.0
HFD3_k127_2148599_1 Dehydrogenase E1 component K21416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008796 378.0
HFD3_k127_2148599_2 of components of various dehydrogenase complexes K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000001211 236.0
HFD3_k127_2148599_3 transketolase activity K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000009248 160.0
HFD3_k127_2148599_4 dTDP-glucose pyrophosphorylase K00973 - 2.7.7.24 0.000000000000006439 76.0
HFD3_k127_2149415_0 ATP-dependent helicase C-terminal K03579 - 3.6.4.13 6.514e-309 968.0
HFD3_k127_2149415_1 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 528.0
HFD3_k127_2149415_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005727 412.0
HFD3_k127_2149415_3 Putative esterase K07214 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008536 366.0
HFD3_k127_2149415_4 ABC-2 type transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 350.0
HFD3_k127_2149415_5 Pseudouridine synthase K06177 - 5.4.99.28,5.4.99.29 0.0000000000000000000000000000000000000000000000000000000000000000002265 254.0
HFD3_k127_2149415_6 - - - - 0.000000000000000000000000000000000000000000000000000266 197.0
HFD3_k127_2149415_7 von Willebrand factor, type A - - - 0.00000000001528 76.0
HFD3_k127_2149415_8 PA domain - - - 0.0000000004071 70.0
HFD3_k127_2217514_0 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 499.0
HFD3_k127_2217514_1 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000002547 190.0
HFD3_k127_2217514_2 Bacterial extracellular solute-binding protein K22003 - 5.3.3.7 0.0000000000000000000000000000000000000000001443 168.0
HFD3_k127_2217514_3 DSBA-like thioredoxin domain K21990 - - 0.0000000000000000000000000000000008785 139.0
HFD3_k127_2217514_4 Belongs to the transketolase family K00615 - 2.2.1.1 0.000000000000009076 89.0
HFD3_k127_2217514_5 Vitamin k epoxide reductase - - - 0.000000000001275 75.0
HFD3_k127_2281407_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1391.0
HFD3_k127_2281407_1 dehydrogenase e1 component K00164 - 1.2.4.2 0.0 1178.0
HFD3_k127_2281407_10 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000002441 58.0
HFD3_k127_2281407_11 TIGRFAM sulfate adenylyltransferase, small subunit K00957 - 2.7.7.4 0.0002926 46.0
HFD3_k127_2281407_2 Carbamoyltransferase C-terminus K00612 - - 2.1e-283 879.0
HFD3_k127_2281407_3 S-acyltransferase activity K00627 GO:0003674,GO:0003824,GO:0004742,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016407,GO:0016417,GO:0016418,GO:0016740,GO:0016746,GO:0016747,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030523,GO:0031405,GO:0031406,GO:0032787,GO:0032991,GO:0033293,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1902494,GO:1990204 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000045 480.0
HFD3_k127_2281407_4 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003597 455.0
HFD3_k127_2281407_5 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 428.0
HFD3_k127_2281407_6 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.0000000000000000000000000000000000001483 143.0
HFD3_k127_2281407_7 - - - - 0.000000000000000000000000001312 129.0
HFD3_k127_2310215_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 7.163e-218 683.0
HFD3_k127_2310215_1 Dehydrogenase K00117 - 1.1.5.2 8.45e-208 668.0
HFD3_k127_2310215_10 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 - - 0.0000000000000000000001364 102.0
HFD3_k127_2310215_11 Involved in the tonB-independent uptake of proteins - - - 0.0000000000001383 72.0
HFD3_k127_2310215_12 - - - - 0.00000000003599 74.0
HFD3_k127_2310215_15 SnoaL-like domain - - - 0.00000006898 63.0
HFD3_k127_2310215_16 transmembrane transport - - - 0.0000001912 55.0
HFD3_k127_2310215_17 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.00000372 50.0
HFD3_k127_2310215_18 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000007459 53.0
HFD3_k127_2310215_19 Ompa motb domain protein - - - 0.00002173 48.0
HFD3_k127_2310215_2 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 549.0
HFD3_k127_2310215_20 SnoaL-like domain - - - 0.00006179 51.0
HFD3_k127_2310215_3 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003772 493.0
HFD3_k127_2310215_5 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000004389 254.0
HFD3_k127_2310215_6 PQQ enzyme repeat K00114 - 1.1.2.8 0.00000000000000000000000000000000002056 142.0
HFD3_k127_2310215_8 PQQ-like domain K00114 - 1.1.2.8 0.000000000000000000000009316 111.0
HFD3_k127_2310215_9 Fibronectin type III domain protein - - - 0.00000000000000000000006872 111.0
HFD3_k127_2342590_0 phosphatase K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000764 449.0
HFD3_k127_2342590_1 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 344.0
HFD3_k127_2342590_2 Putative restriction endonuclease - - - 0.00000000000000000000000000000000000000004779 165.0
HFD3_k127_2342590_3 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000189 147.0
HFD3_k127_2342590_4 Serine threonine protein kinase - - - 0.0000000000000000000000000000002227 123.0
HFD3_k127_2342590_5 YceI-like domain - - - 0.0000000000000000000008258 103.0
HFD3_k127_2345634_0 ABC transporter transmembrane region K06147 - - 2.469e-226 715.0
HFD3_k127_2345634_1 ABC transporter, transmembrane region K06147 - - 2.326e-224 710.0
HFD3_k127_2345634_10 NADP oxidoreductase coenzyme F420-dependent - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 304.0
HFD3_k127_2345634_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 295.0
HFD3_k127_2345634_12 YjgF/chorismate_mutase-like, putative endoribonuclease - - - 0.000000000000000000000000000000000000000000000000003018 186.0
HFD3_k127_2345634_13 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000004889 181.0
HFD3_k127_2345634_14 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000000000000009801 161.0
HFD3_k127_2345634_15 Domain of unknown function (DUF4034) - - - 0.00000000000000000000000000000000000000007497 166.0
HFD3_k127_2345634_16 COG0346 Lactoylglutathione lyase and related lyases - - - 0.00000000000000000000000000000000000001276 158.0
HFD3_k127_2345634_17 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000005323 145.0
HFD3_k127_2345634_18 peroxiredoxin activity K01607 - 4.1.1.44 0.0000000000000000000000000000000000005303 142.0
HFD3_k127_2345634_19 glyoxalase III activity - - - 0.0000000000000000000000000000000001189 145.0
HFD3_k127_2345634_2 Flavin containing amine oxidoreductase K09516 - 1.3.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 574.0
HFD3_k127_2345634_20 type IV pilus secretin PilQ K02666 - - 0.0000000000000000002252 95.0
HFD3_k127_2345634_21 Dehydrogenase K00114,K17760 - 1.1.2.8,1.1.9.1 0.000000000001869 69.0
HFD3_k127_2345634_22 - - - - 0.00000000001205 72.0
HFD3_k127_2345634_23 A domain in the BMP inhibitor chordin and in microbial proteins. - - - 0.00000000002263 70.0
HFD3_k127_2345634_24 cAMP biosynthetic process - - - 0.0000000008907 63.0
HFD3_k127_2345634_25 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009405,GO:0009605,GO:0009607,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030312,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0035821,GO:0036094,GO:0040007,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043207,GO:0043492,GO:0043952,GO:0044003,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0050896,GO:0051179,GO:0051234,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052564,GO:0052572,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0075136,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.000000002439 61.0
HFD3_k127_2345634_26 Ankyrin repeat - - - 0.0000001125 60.0
HFD3_k127_2345634_27 Activator of hsp90 atpase 1 family protein - - - 0.000003716 58.0
HFD3_k127_2345634_28 - - - - 0.00000596 55.0
HFD3_k127_2345634_3 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 522.0
HFD3_k127_2345634_4 response to abiotic stimulus K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 505.0
HFD3_k127_2345634_5 Dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 503.0
HFD3_k127_2345634_6 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 497.0
HFD3_k127_2345634_7 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 462.0
HFD3_k127_2345634_8 Cupin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 411.0
HFD3_k127_2345634_9 antibiotic catabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 324.0
HFD3_k127_2347006_0 PQQ-like domain K05889 - 1.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 617.0
HFD3_k127_2347006_1 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity K03429 - 2.4.1.315 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004442 503.0
HFD3_k127_2347006_10 Subtilase family K14645 - - 0.000000000000000000000000000000000000000000000002546 190.0
HFD3_k127_2347006_11 Tetratricopeptide repeat - - - 0.0000000000000000000000000000002418 139.0
HFD3_k127_2347006_2 Dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 471.0
HFD3_k127_2347006_3 'ABC-type proline glycine betaine transport K05847 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008169 313.0
HFD3_k127_2347006_4 Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 321.0
HFD3_k127_2347006_5 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004882 307.0
HFD3_k127_2347006_6 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004388 279.0
HFD3_k127_2347006_7 PFAM peptidase T2 asparaginase 2 K13051 - 3.4.19.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002554 275.0
HFD3_k127_2347006_8 PFAM Binding-protein-dependent transport system inner membrane component K05846 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001709 259.0
HFD3_k127_2347006_9 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.00000000000000000000000000000000000000000000000000000000000000002276 229.0
HFD3_k127_238409_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007081 552.0
HFD3_k127_238409_1 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004713 506.0
HFD3_k127_238409_2 3-beta hydroxysteroid dehydrogenase/isomerase family K01710,K08678 - 4.1.1.35,4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 473.0
HFD3_k127_238409_3 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007611 385.0
HFD3_k127_238409_4 - - - - 0.0000000000000000000000000000000000000000001689 159.0
HFD3_k127_238409_5 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000000003805 156.0
HFD3_k127_238409_6 - - - - 0.00000000000002056 76.0
HFD3_k127_238409_7 - K02172 - - 0.00000001049 66.0
HFD3_k127_238521_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1298.0
HFD3_k127_238521_1 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008334 462.0
HFD3_k127_238521_2 PFAM cytochrome bd ubiquinol oxidase subunit II K00426 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 307.0
HFD3_k127_238521_3 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001278 280.0
HFD3_k127_238521_4 Phosphoribosyl transferase domain K07100 - - 0.0000000000000000000000000000000000000000000000000000000000000851 219.0
HFD3_k127_238521_5 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000002318 201.0
HFD3_k127_238521_6 Protein of unknown function (DUF2892) - - - 0.0000000000000000003199 90.0
HFD3_k127_240522_0 FtsX-like permease family K02004 - - 4.047e-251 799.0
HFD3_k127_240522_1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 542.0
HFD3_k127_240522_2 (ABC) transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005767 351.0
HFD3_k127_240522_3 HlyD family secretion protein K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 321.0
HFD3_k127_240522_4 - - - - 0.000000000000000000000000000000000000000000000000000000006685 203.0
HFD3_k127_240522_5 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000001478 199.0
HFD3_k127_240522_6 Putative restriction endonuclease - - - 0.000000000000000000000000000000905 128.0
HFD3_k127_240697_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 392.0
HFD3_k127_240697_1 4Fe-4S dicluster domain K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000001498 192.0
HFD3_k127_240697_2 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000000000000000000002928 149.0
HFD3_k127_240697_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000000002234 127.0
HFD3_k127_240697_4 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.000000001842 60.0
HFD3_k127_2460672_0 Belongs to the ClpA ClpB family K03696 - - 0.0 1212.0
HFD3_k127_2460672_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1187.0
HFD3_k127_2460672_10 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005336 370.0
HFD3_k127_2460672_11 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004064 352.0
HFD3_k127_2460672_12 Protein of unknown function (DUF512) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 353.0
HFD3_k127_2460672_13 ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 331.0
HFD3_k127_2460672_14 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 331.0
HFD3_k127_2460672_15 Protein of unknown function (DUF1009) K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 323.0
HFD3_k127_2460672_16 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009132 333.0
HFD3_k127_2460672_17 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 301.0
HFD3_k127_2460672_18 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 290.0
HFD3_k127_2460672_19 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000159 287.0
HFD3_k127_2460672_2 oxidoreductase activity - - - 7.93e-247 780.0
HFD3_k127_2460672_20 MacB-like periplasmic core domain K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001963 291.0
HFD3_k127_2460672_21 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003439 286.0
HFD3_k127_2460672_22 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000001389 242.0
HFD3_k127_2460672_23 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000001045 199.0
HFD3_k127_2460672_24 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000000000000000000000000000001225 216.0
HFD3_k127_2460672_25 nucleotide metabolic process - - - 0.0000000000000000000000000000000000000000000000000002137 192.0
HFD3_k127_2460672_26 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000002368 193.0
HFD3_k127_2460672_27 Belongs to the ClpA ClpB family K03696 - - 0.0000000000000000000000000000000000000000000000001277 185.0
HFD3_k127_2460672_28 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000003461 173.0
HFD3_k127_2460672_29 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.00000000000000000000000000000000000002698 147.0
HFD3_k127_2460672_3 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009444 640.0
HFD3_k127_2460672_30 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000004661 141.0
HFD3_k127_2460672_31 BMC K04027 - - 0.00000000000000000000000000000003502 127.0
HFD3_k127_2460672_32 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.41 0.0000000000000000000000000000001248 132.0
HFD3_k127_2460672_33 PTS system fructose IIA component K02793,K02794,K02821 - 2.7.1.191,2.7.1.194 0.0000000000000000000000000000001401 128.0
HFD3_k127_2460672_34 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000000009856 98.0
HFD3_k127_2460672_35 TonB C terminal - - - 0.00000000000000000001785 103.0
HFD3_k127_2460672_36 Helix-turn-helix domain - - - 0.00000000000000001858 94.0
HFD3_k127_2460672_37 Cell wall-active antibiotics response 4TMS YvqF - - - 0.00000000000000005109 89.0
HFD3_k127_2460672_38 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000001263 86.0
HFD3_k127_2460672_39 phosphocarrier protein HPr K11189 - - 0.000000000009686 73.0
HFD3_k127_2460672_4 Surface antigen variable number K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 571.0
HFD3_k127_2460672_40 - - - - 0.000000005577 63.0
HFD3_k127_2460672_41 Outer membrane protein (OmpH-like) K06142 - - 0.0000001266 63.0
HFD3_k127_2460672_42 TPR repeat - - - 0.000004726 58.0
HFD3_k127_2460672_43 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00002168 56.0
HFD3_k127_2460672_44 - - - - 0.00003552 53.0
HFD3_k127_2460672_45 repeat-containing protein - - - 0.00005781 55.0
HFD3_k127_2460672_46 Phosphodiester glycosidase - - - 0.0008873 51.0
HFD3_k127_2460672_5 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009099 530.0
HFD3_k127_2460672_6 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009813 550.0
HFD3_k127_2460672_7 Aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005865 507.0
HFD3_k127_2460672_8 RNA polymerase sigma-54 factor K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 468.0
HFD3_k127_2460672_9 ABC transporter K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 460.0
HFD3_k127_2478965_0 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001411 289.0
HFD3_k127_2478965_1 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000005871 260.0
HFD3_k127_2478965_2 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000006824 196.0
HFD3_k127_2478965_3 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.000000000000008945 75.0
HFD3_k127_2488060_0 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004293 507.0
HFD3_k127_2488060_1 PFAM Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003511 389.0
HFD3_k127_2488060_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002328 273.0
HFD3_k127_2488060_3 TIGRFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000002314 265.0
HFD3_k127_2488060_4 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000003668 207.0
HFD3_k127_2488060_5 Regulatory protein, FmdB - - - 0.000000000000000000005159 96.0
HFD3_k127_2488060_6 haloacid dehalogenase-like hydrolase K01079 - 3.1.3.3 0.0000000000000000001076 98.0
HFD3_k127_2488060_7 nitrite reductase K00363 - 1.7.1.15 0.000000000000000003819 91.0
HFD3_k127_2488060_8 - - - - 0.000000000002758 75.0
HFD3_k127_249528_0 Uncharacterized conserved protein (DUF2075) - - - 6.505e-266 833.0
HFD3_k127_249528_1 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 422.0
HFD3_k127_249528_2 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 360.0
HFD3_k127_249528_3 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000001993 238.0
HFD3_k127_249528_4 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000219 177.0
HFD3_k127_2495395_0 Amidohydrolase K03392,K10220 - 4.1.1.45,4.2.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 557.0
HFD3_k127_2495395_1 Oxidoreductase family, NAD-binding Rossmann fold K10219 - 1.1.1.312 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 471.0
HFD3_k127_2495395_2 beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 355.0
HFD3_k127_2495395_3 Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively K04099,K04101 - 1.13.11.57,1.13.11.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009785 344.0
HFD3_k127_2495395_4 ribonuclease inhibitor activity K10218 - 4.1.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004094 315.0
HFD3_k127_2495395_5 Aldolase/RraA - - - 0.000000000000000000000000000000000000000000000000000000000000000000002232 241.0
HFD3_k127_2495395_6 Transposase IS200 like K07491 - - 0.0000001062 55.0
HFD3_k127_2495395_7 Transposase K03589,K07491 - - 0.0002009 46.0
HFD3_k127_2500145_0 ASPIC and UnbV - - - 2.416e-321 1019.0
HFD3_k127_2500145_1 ASPIC and UnbV - - - 3.501e-236 742.0
HFD3_k127_2500145_2 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004569 552.0
HFD3_k127_2500145_3 Amidase K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000621 486.0
HFD3_k127_2500145_4 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004196 283.0
HFD3_k127_2500145_5 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000005826 148.0
HFD3_k127_2500145_6 peptidyl-tyrosine sulfation - - - 0.0000000000000303 85.0
HFD3_k127_2520969_0 PQQ-like domain K00114 - 1.1.2.8 2.892e-257 802.0
HFD3_k127_2520969_1 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 343.0
HFD3_k127_2520969_2 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006965 263.0
HFD3_k127_2520969_3 Glycoside hydrolase, family 19 K03791 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007034 264.0
HFD3_k127_2522712_0 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000388 402.0
HFD3_k127_2522712_1 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000451 403.0
HFD3_k127_2547593_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1086.0
HFD3_k127_2547593_1 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008435 328.0
HFD3_k127_2547593_2 Domain of unkown function (DUF1775) - - - 0.0000000000000000000000000000008063 127.0
HFD3_k127_2547593_3 - - - - 0.000000000000006051 78.0
HFD3_k127_2547593_4 YtkA-like - - - 0.000006165 53.0
HFD3_k127_2555929_0 Aldehyde dehydrogenase family K00128,K00146 - 1.2.1.3,1.2.1.39 2.203e-240 753.0
HFD3_k127_2555929_1 Cytochrome c, class I - - - 2.296e-240 767.0
HFD3_k127_2555929_10 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003653 404.0
HFD3_k127_2555929_11 [glutamate-ammonia-ligase] adenylyltransferase activity K00982 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698 2.7.7.42,2.7.7.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 385.0
HFD3_k127_2555929_12 Protein of unknown function (DUF1552) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 374.0
HFD3_k127_2555929_13 ankyrin repeat K15503 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 369.0
HFD3_k127_2555929_14 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 303.0
HFD3_k127_2555929_15 lyase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000513 285.0
HFD3_k127_2555929_16 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000033 242.0
HFD3_k127_2555929_17 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001382 246.0
HFD3_k127_2555929_18 Redox protein regulator of disulfide bond formation K06889,K07397 - - 0.00000000000000000000000000000000000000000000001675 177.0
HFD3_k127_2555929_19 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000000000000000000002271 182.0
HFD3_k127_2555929_2 DNA topological change K03168 - 5.99.1.2 5.084e-224 721.0
HFD3_k127_2555929_20 PadR family transcriptional regulator K10947 - - 0.0000000000000000000000000000000001048 136.0
HFD3_k127_2555929_21 ankyrin repeat K15502,K15503,K15504 - - 0.000000000000000000000000000014 135.0
HFD3_k127_2555929_22 Helix-hairpin-helix motif K02237 - - 0.000000000000000000000003202 110.0
HFD3_k127_2555929_23 Acetyltransferase (GNAT) domain - - - 0.00000000000000000002643 96.0
HFD3_k127_2555929_25 Cellulose synthase K20543 - - 0.0002402 54.0
HFD3_k127_2555929_3 pyrroloquinoline quinone binding - - - 5.005e-216 683.0
HFD3_k127_2555929_4 ABC transporter transmembrane region K06147,K18893 - - 5.501e-207 662.0
HFD3_k127_2555929_5 DNA topological change K03168 - 5.99.1.2 4.176e-198 644.0
HFD3_k127_2555929_6 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 619.0
HFD3_k127_2555929_7 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00003,K00982,K00990,K06950,K15371 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698 1.1.1.3,1.4.1.2,2.7.7.42,2.7.7.59,2.7.7.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005728 593.0
HFD3_k127_2555929_8 Protein of unknown function (DUF1552) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006993 454.0
HFD3_k127_2555929_9 Glycosyltransferase like family 2 K11936 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 452.0
HFD3_k127_2627087_0 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007519 367.0
HFD3_k127_2627087_1 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000002112 157.0
HFD3_k127_2627087_2 Protein of unknown function (DUF3738) - - - 0.000000000000000000000000000000000000000493 168.0
HFD3_k127_2627087_3 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000000001246 133.0
HFD3_k127_2627087_4 Sigma-70 region 2 K03088 - - 0.000000000000000000001196 103.0
HFD3_k127_2627087_5 Metallo-beta-lactamase superfamily - - - 0.0000000000009194 74.0
HFD3_k127_26487_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 488.0
HFD3_k127_26487_1 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005957 458.0
HFD3_k127_26487_2 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006498 382.0
HFD3_k127_26487_3 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.0000000000000000001491 89.0
HFD3_k127_266378_0 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007046 466.0
HFD3_k127_266378_1 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000522 330.0
HFD3_k127_266378_2 Branched-chain amino acid transport system / permease component K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 315.0
HFD3_k127_266378_3 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008793 305.0
HFD3_k127_266378_4 ABC transporter related K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 301.0
HFD3_k127_266378_5 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000002324 193.0
HFD3_k127_266378_6 Putative restriction endonuclease - - - 0.00000000000000000000000000000000001886 138.0
HFD3_k127_266378_7 Putative restriction endonuclease - - - 0.0000000000007114 70.0
HFD3_k127_266378_8 Unextendable partial coding region - - - 0.0000000001375 61.0
HFD3_k127_266378_9 Transglycosylase SLT domain - - - 0.00000008492 63.0
HFD3_k127_2753369_0 Proton-conducting membrane transporter K12137,K15828 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 9.577e-245 773.0
HFD3_k127_2753369_1 Proton-conducting membrane transporter K12141 GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0033554,GO:0044425,GO:0044464,GO:0050896,GO:0051716,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009781 592.0
HFD3_k127_2753369_2 NADH dehydrogenase K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 426.0
HFD3_k127_2753369_3 NADH dehydrogenase (ubiquinone) activity K14089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008322 364.0
HFD3_k127_2753369_4 Hydrogenase 4 membrane K12140 GO:0008150,GO:0040007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003422 263.0
HFD3_k127_2753369_5 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006716 262.0
HFD3_k127_2753369_6 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000003372 157.0
HFD3_k127_2762269_0 BFD-like [2Fe-2S] binding domain K00362 - 1.7.1.15 0.0 1347.0
HFD3_k127_2762269_1 orotate phosphoribosyltransferase activity K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000005522 224.0
HFD3_k127_2762269_2 Rieske-like [2Fe-2S] domain - - - 0.0000000000000000000000000000000007771 140.0
HFD3_k127_2762269_3 PFAM Rieske 2Fe-2S domain protein - - - 0.000000000000000000000000000000003179 132.0
HFD3_k127_2762269_6 Alpha/beta hydrolase family - - - 0.0001847 45.0
HFD3_k127_2774559_0 Peptidase M16C associated K06972 - - 3.484e-312 992.0
HFD3_k127_2774559_1 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 4.314e-262 836.0
HFD3_k127_2774559_10 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000005756 213.0
HFD3_k127_2774559_11 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000006391 194.0
HFD3_k127_2774559_12 Sigma factor PP2C-like phosphatases - - - 0.0000000000000000000000000000000002 143.0
HFD3_k127_2774559_13 Pyridoxamine 5'-phosphate oxidase - - - 0.00001187 53.0
HFD3_k127_2774559_2 PQQ enzyme repeat K00117 - 1.1.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003114 589.0
HFD3_k127_2774559_3 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 561.0
HFD3_k127_2774559_4 CobW/HypB/UreG, nucleotide-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005605 522.0
HFD3_k127_2774559_5 PQQ-like domain K05889 - 1.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008377 422.0
HFD3_k127_2774559_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004923 352.0
HFD3_k127_2774559_7 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000001958 258.0
HFD3_k127_2774559_8 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000009401 217.0
HFD3_k127_2774559_9 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000001647 217.0
HFD3_k127_279423_0 PQQ-like domain K00117 - 1.1.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003512 626.0
HFD3_k127_279423_1 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 431.0
HFD3_k127_279423_2 lactoylglutathione lyase activity K03088 - - 0.00000000000000000000000000000000000000004647 165.0
HFD3_k127_279423_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000001422 138.0
HFD3_k127_279423_4 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000006731 137.0
HFD3_k127_279423_5 heme-binding domain, Pirellula Verrucomicrobium type K01256,K09992 - 3.4.11.2 0.00004623 51.0
HFD3_k127_2846779_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 355.0
HFD3_k127_2846779_1 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005507 355.0
HFD3_k127_2846779_2 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000006853 139.0
HFD3_k127_2846779_3 - - - - 0.00000000000000000000000000003467 128.0
HFD3_k127_2846779_4 - - - - 0.000000000000000000000000001974 119.0
HFD3_k127_2846779_5 Glycosyltransferase family 87 - - - 0.000003493 59.0
HFD3_k127_2885386_0 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 9.001e-249 777.0
HFD3_k127_2885386_1 FAD binding domain - - - 2.565e-228 713.0
HFD3_k127_2885386_10 Enoyl-(Acyl carrier protein) reductase K07124 - - 0.000000000000000000000000000000000000000000000000000000004492 214.0
HFD3_k127_2885386_11 - - - - 0.00000000000000000000000000000000000000000000000002582 190.0
HFD3_k127_2885386_12 Transposase IS200 like K07491 - - 0.000000000000000000000000000000000000000000002049 177.0
HFD3_k127_2885386_13 Heavy-metal resistance - - - 0.000000000000000000000000000000000008741 141.0
HFD3_k127_2885386_14 BON domain - - - 0.00000000000000000000000000000000001745 143.0
HFD3_k127_2885386_15 Bacterial regulatory proteins, luxR family - - - 0.000000000000000000000000000001441 130.0
HFD3_k127_2885386_16 - - - - 0.000000000000000000000000001112 123.0
HFD3_k127_2885386_17 - - - - 0.000000000000000000000000008176 116.0
HFD3_k127_2885386_18 - - - - 0.00000000000000000000000354 109.0
HFD3_k127_2885386_19 - - - - 0.0000000000000000009908 90.0
HFD3_k127_2885386_2 lysine biosynthetic process via aminoadipic acid - - - 2.3e-209 680.0
HFD3_k127_2885386_20 Fatty acid hydroxylase - - - 0.000000000000002694 85.0
HFD3_k127_2885386_22 - - - - 0.00000000008395 68.0
HFD3_k127_2885386_23 Domain of unknown function (DUF4136) - - - 0.0000001992 60.0
HFD3_k127_2885386_24 - - - - 0.000121 52.0
HFD3_k127_2885386_25 FOG TPR repeat - - - 0.0004737 49.0
HFD3_k127_2885386_26 - - - - 0.000807 51.0
HFD3_k127_2885386_3 Protein of unknown function (DUF3999) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 336.0
HFD3_k127_2885386_4 Glucose / Sorbosone dehydrogenase K21430 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005525 323.0
HFD3_k127_2885386_5 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 297.0
HFD3_k127_2885386_6 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003278 280.0
HFD3_k127_2885386_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002809 263.0
HFD3_k127_2885386_8 PFAM PDZ domain (Also known as DHR or GLGF) - - - 0.000000000000000000000000000000000000000000000000000000000000003828 227.0
HFD3_k127_2885386_9 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000616 210.0
HFD3_k127_2903134_0 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 568.0
HFD3_k127_2903134_1 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 513.0
HFD3_k127_2903134_2 SAICAR synthetase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 389.0
HFD3_k127_2903134_3 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K14161 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003981 379.0
HFD3_k127_2903134_4 PFAM Colicin V production K03558 - - 0.000000000000000000000002794 109.0
HFD3_k127_2903134_5 PFAM helix-turn-helix, Fis-type - - - 0.0000000004131 65.0
HFD3_k127_2906568_0 ATPases associated with a variety of cellular activities K10441 - 3.6.3.17 3.768e-204 646.0
HFD3_k127_2906568_1 Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 527.0
HFD3_k127_2906568_10 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002882 278.0
HFD3_k127_2906568_11 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006891 256.0
HFD3_k127_2906568_12 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000249 233.0
HFD3_k127_2906568_13 Peptidase, M16 K07263 - - 0.000000000000000000000000000000000000000000000000000000007836 213.0
HFD3_k127_2906568_14 - - - - 0.00000000000000000000009189 102.0
HFD3_k127_2906568_15 DNA-binding transcription factor activity K03892 GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0043170,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0046685,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000001204 90.0
HFD3_k127_2906568_16 Cupin domain - - - 0.0000000000002782 72.0
HFD3_k127_2906568_17 NAD(P)H dehydrogenase (quinone) activity K03809 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 1.6.5.2 0.0000000002994 67.0
HFD3_k127_2906568_18 Anaphase-promoting complex, cyclosome, subunit 3 K03350 GO:0000070,GO:0000151,GO:0000152,GO:0000278,GO:0000280,GO:0000819,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005680,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0006996,GO:0007049,GO:0007050,GO:0007059,GO:0007088,GO:0007346,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009896,GO:0009987,GO:0010498,GO:0010564,GO:0010638,GO:0010965,GO:0016043,GO:0016567,GO:0019538,GO:0019941,GO:0022402,GO:0030071,GO:0030163,GO:0031145,GO:0031331,GO:0031461,GO:0031974,GO:0031981,GO:0032270,GO:0032436,GO:0032446,GO:0032991,GO:0033043,GO:0033044,GO:0033045,GO:0033047,GO:0034399,GO:0036211,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0045732,GO:0045786,GO:0045787,GO:0045840,GO:0045842,GO:0045862,GO:0045930,GO:0045931,GO:0048285,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051247,GO:0051276,GO:0051603,GO:0051726,GO:0051781,GO:0051783,GO:0051785,GO:0051983,GO:0051984,GO:0062033,GO:0065007,GO:0070013,GO:0070647,GO:0071704,GO:0071840,GO:0071849,GO:0071850,GO:0071851,GO:0090068,GO:0097159,GO:0098813,GO:0140014,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901800,GO:1901970,GO:1901987,GO:1901989,GO:1901990,GO:1901992,GO:1902099,GO:1902101,GO:1902494,GO:1903047,GO:1903052,GO:1903364,GO:1905818,GO:1905820,GO:1990234,GO:2001252 - 0.0000001134 61.0
HFD3_k127_2906568_2 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 524.0
HFD3_k127_2906568_3 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 389.0
HFD3_k127_2906568_4 Periplasmic binding proteins and sugar binding domain of LacI family K10439,K17202,K17205,K17213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 380.0
HFD3_k127_2906568_5 Belongs to the binding-protein-dependent transport system permease family K10440,K17214 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007501 377.0
HFD3_k127_2906568_6 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 353.0
HFD3_k127_2906568_7 Biotin-lipoyl like K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 359.0
HFD3_k127_2906568_8 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 291.0
HFD3_k127_2906568_9 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003302 281.0
HFD3_k127_291292_0 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049,K15579 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 289.0
HFD3_k127_291292_1 ATPases associated with a variety of cellular activities K02049,K15578 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009954 245.0
HFD3_k127_291292_2 Periplasmic or secreted lipoprotein - - - 0.000000004329 68.0
HFD3_k127_2916892_0 heat shock protein binding - - - 1.119e-194 625.0
HFD3_k127_2916892_1 heat shock protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 506.0
HFD3_k127_2916892_2 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005976 351.0
HFD3_k127_2916892_3 ferredoxin-NADP+ reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007152 255.0
HFD3_k127_2916892_5 COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain K02030 - - 0.000000000000000000178 99.0
HFD3_k127_2916892_6 COG0457 FOG TPR repeat - - - 0.00000002205 63.0
HFD3_k127_2916892_7 oxidoreductase activity - - - 0.00001506 47.0
HFD3_k127_2930399_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.076e-272 851.0
HFD3_k127_2930399_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005106 565.0
HFD3_k127_2930399_2 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 363.0
HFD3_k127_2930399_3 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000001225 268.0
HFD3_k127_2930399_4 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000006469 258.0
HFD3_k127_2930399_5 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000001969 238.0
HFD3_k127_2930399_6 - - - - 0.00000000000000000000000000002708 120.0
HFD3_k127_2930399_7 - - - - 0.00000000000000000000000003317 109.0
HFD3_k127_2930399_8 YbbR-like protein - - - 0.0000000000000000000000002951 114.0
HFD3_k127_2930399_9 - - - - 0.00000000000001659 74.0
HFD3_k127_2983065_0 PQQ enzyme repeat K00117 - 1.1.5.2 3.2e-228 729.0
HFD3_k127_2983065_1 PFAM monooxygenase FAD-binding K20940 - 1.14.13.218 2.545e-203 639.0
HFD3_k127_2983065_2 Belongs to the glycosyl hydrolase 28 family - - - 5.093e-197 628.0
HFD3_k127_2983065_3 Cys/Met metabolism PLP-dependent enzyme K10907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 410.0
HFD3_k127_2983065_4 phospholipase Carboxylesterase - - - 0.0000000000000000000000000000005702 135.0
HFD3_k127_2983065_5 Stress responsive A/B Barrel Domain - - - 0.00000000000000000000000004663 113.0
HFD3_k127_2983065_6 Metallo-beta-lactamase superfamily - - - 0.0002151 49.0
HFD3_k127_2998769_0 PFAM Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000001175 238.0
HFD3_k127_2998769_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000479 223.0
HFD3_k127_2998769_2 Serine aminopeptidase, S33 K03928 - 3.1.1.1 0.00000000000000000000000002197 124.0
HFD3_k127_2998769_3 TonB-dependent Receptor Plug Domain - - - 0.000000000000000000104 94.0
HFD3_k127_2998769_4 COG3209 Rhs family protein - - - 0.000003882 59.0
HFD3_k127_2999516_0 protease with the C-terminal PDZ domain - - - 2.577e-264 829.0
HFD3_k127_2999516_1 Belongs to the TPP enzyme family K01576,K01652 - 2.2.1.6,4.1.1.7 1.422e-228 727.0
HFD3_k127_2999516_10 TraB family K09973 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 342.0
HFD3_k127_2999516_11 Pectinesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 325.0
HFD3_k127_2999516_12 peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001525 264.0
HFD3_k127_2999516_13 TLC ATP/ADP transporter K03301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003771 284.0
HFD3_k127_2999516_14 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009041 263.0
HFD3_k127_2999516_15 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004853 254.0
HFD3_k127_2999516_16 Protein of unknown function (DUF4243) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001079 252.0
HFD3_k127_2999516_17 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000001372 247.0
HFD3_k127_2999516_18 Uncharacterized protein conserved in bacteria (DUF2087) - - - 0.000000000000000000000000000000000000000000000000000000000000000683 224.0
HFD3_k127_2999516_2 Pfam:KaiC K08482 - - 5.895e-228 719.0
HFD3_k127_2999516_20 Belongs to the UPF0502 family K09915 - - 0.000000000000000000000000000000000000000000000000000000000001744 215.0
HFD3_k127_2999516_21 phosphoprotein phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000002663 222.0
HFD3_k127_2999516_22 Transcriptional regulator K13652 - - 0.000000000000000000000000000000000000000000000000000002787 203.0
HFD3_k127_2999516_23 Bacterial transcriptional activator domain - - - 0.0000000000000000000000000000000000000000000000000002778 194.0
HFD3_k127_2999516_24 phosphoprotein phosphatase activity K14680 - 6.5.1.3 0.000000000000000000000000000000000000000000009763 172.0
HFD3_k127_2999516_25 DoxX-like family - - - 0.000000000000000000000000000000000000000000025 165.0
HFD3_k127_2999516_26 - - - - 0.00000000000000000000000000000000000000000005902 173.0
HFD3_k127_2999516_27 Histidine kinase - - - 0.0000000000000000000000000000000000000000005581 172.0
HFD3_k127_2999516_28 Bacterial extracellular solute-binding protein K22003 - 5.3.3.7 0.0000000000000000000000000000000000000000077 166.0
HFD3_k127_2999516_29 Cupin 2, conserved barrel domain protein K00450,K01628 - 1.13.11.4,4.1.2.17 0.0000000000000000000000000000000000000001173 155.0
HFD3_k127_2999516_3 Carboxypeptidase regulatory-like domain - - - 7.703e-222 727.0
HFD3_k127_2999516_30 KaiB K08481 - - 0.00000000000000000000000000000000000002561 147.0
HFD3_k127_2999516_32 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000004485 148.0
HFD3_k127_2999516_33 Glyoxalase-like domain K06996 - - 0.00000000000000000000000000000005884 140.0
HFD3_k127_2999516_34 - - - - 0.00000000000000000000000427 106.0
HFD3_k127_2999516_35 - - - - 0.0000000000000000000001116 102.0
HFD3_k127_2999516_36 - - - - 0.000000000000000000001651 104.0
HFD3_k127_2999516_37 Cytochrome c K17760 - 1.1.9.1 0.0000000000000000004393 93.0
HFD3_k127_2999516_38 phosphatidate phosphatase activity K19302 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009605,GO:0009607,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0042578,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0046467,GO:0046493,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0071704,GO:0075136,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.27 0.000000000000000007273 94.0
HFD3_k127_2999516_4 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004868 626.0
HFD3_k127_2999516_40 HIT domain - - - 0.00000000000001685 85.0
HFD3_k127_2999516_41 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000001172 77.0
HFD3_k127_2999516_42 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.000000001414 65.0
HFD3_k127_2999516_43 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.0000003119 62.0
HFD3_k127_2999516_44 Adenylate cyclase - - - 0.0000005263 51.0
HFD3_k127_2999516_46 - - - - 0.0002882 52.0
HFD3_k127_2999516_5 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005793 612.0
HFD3_k127_2999516_6 Belongs to the glycosyl hydrolase 28 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 566.0
HFD3_k127_2999516_7 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 508.0
HFD3_k127_2999516_8 beta-lactamase activity K07126 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 396.0
HFD3_k127_2999516_9 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15061 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 374.0
HFD3_k127_3010372_0 Dehydrogenase E1 component K00615 - 2.2.1.1 1.41e-299 938.0
HFD3_k127_3010372_1 Cysteine-rich domain K00113 - 1.1.5.3 2.932e-211 665.0
HFD3_k127_3010372_10 Protein of unknown function (DUF3501) - - - 0.0000000000000000000000000000000000000000000000000002978 190.0
HFD3_k127_3010372_11 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000000001518 185.0
HFD3_k127_3010372_13 DoxX-like family - - - 0.0000000000000000000000001831 114.0
HFD3_k127_3010372_14 multi-organism process K03195 - - 0.000000000000000000000001674 111.0
HFD3_k127_3010372_15 - - - - 0.000000000000000000001656 106.0
HFD3_k127_3010372_16 - - - - 0.00000000000000001559 92.0
HFD3_k127_3010372_17 TIGRFAM TonB family protein K03832 - - 0.00000000000000001968 92.0
HFD3_k127_3010372_18 - - - - 0.0000000000000006298 84.0
HFD3_k127_3010372_19 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000298 78.0
HFD3_k127_3010372_2 FAD dependent oxidoreductase - - - 1.172e-201 641.0
HFD3_k127_3010372_20 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.00001571 55.0
HFD3_k127_3010372_3 LysR substrate binding domain K04761 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000676 297.0
HFD3_k127_3010372_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 288.0
HFD3_k127_3010372_5 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000015 252.0
HFD3_k127_3010372_6 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000004117 230.0
HFD3_k127_3010372_7 Uncharacterised protein family (UPF0167) - - - 0.0000000000000000000000000000000000000000000000000000000000000001638 228.0
HFD3_k127_3010372_8 PFAM Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000000000242 216.0
HFD3_k127_3010372_9 COGs COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog K03088 - - 0.000000000000000000000000000000000000000000000000000001286 207.0
HFD3_k127_3055552_0 FAD dependent oxidoreductase K00109,K15736 - 1.1.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 542.0
HFD3_k127_3055552_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 512.0
HFD3_k127_3055552_2 PFAM MOSC N-terminal beta barrel domain K07140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 301.0
HFD3_k127_3055552_3 domain protein K14194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004665 258.0
HFD3_k127_3055552_4 domain protein K14194 - - 0.000000000000000000000000000000000000000000000000000002895 213.0
HFD3_k127_3055552_5 - - - - 0.000000000000000000000000000006834 130.0
HFD3_k127_3055552_6 PFAM Cupin 2, conserved barrel - - - 0.0000000000000000000000001066 110.0
HFD3_k127_3055552_7 - - - - 0.0000171 48.0
HFD3_k127_3072219_0 AMP binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 309.0
HFD3_k127_3072219_1 IMP dehydrogenase activity K07182 - - 0.000000000000000000000000000000000000000000000000000000006631 204.0
HFD3_k127_3072219_3 IMP dehydrogenase activity K07182 - - 0.00000000000000000000000000000000000001271 149.0
HFD3_k127_3072219_4 Cation transporter/ATPase, N-terminus - - - 0.00000000000000000007857 92.0
HFD3_k127_3122095_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01640,K01968 GO:0000287,GO:0003674,GO:0003824,GO:0004419,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005777,GO:0005782,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006552,GO:0006605,GO:0006625,GO:0006629,GO:0006807,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0015031,GO:0015833,GO:0016043,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0017144,GO:0019752,GO:0022607,GO:0030145,GO:0031907,GO:0031974,GO:0033036,GO:0033365,GO:0034613,GO:0042579,GO:0042802,GO:0042803,GO:0042886,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043574,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046395,GO:0046872,GO:0046907,GO:0046914,GO:0046950,GO:0046951,GO:0046983,GO:0051179,GO:0051234,GO:0051259,GO:0051262,GO:0051641,GO:0051649,GO:0065003,GO:0070013,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072594,GO:0072662,GO:0072663,GO:1901564,GO:1901565,GO:1901568,GO:1901570,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902224 4.1.3.4,6.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006386 405.0
HFD3_k127_3122095_1 isobutyryl-CoA mutase activity K07588 - - 0.000000000000000000000000000000000000000003273 161.0
HFD3_k127_3122095_2 Enoyl-CoA hydratase/isomerase K13766,K13779 - 4.2.1.18,4.2.1.57 0.000002018 52.0
HFD3_k127_312787_0 WD40-like Beta Propeller K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 331.0
HFD3_k127_312787_1 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000000002536 177.0
HFD3_k127_312787_2 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000000000003084 156.0
HFD3_k127_312787_3 TonB C terminal K03832 - - 0.000000000000000002689 94.0
HFD3_k127_312787_4 Tetratricopeptide repeat - - - 0.0002248 52.0
HFD3_k127_3139179_0 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000683 473.0
HFD3_k127_3139179_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008856 377.0
HFD3_k127_3139179_2 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000813 338.0
HFD3_k127_3139179_3 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006448 292.0
HFD3_k127_3139179_4 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000003967 267.0
HFD3_k127_3139179_5 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000003638 137.0
HFD3_k127_3169813_0 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 344.0
HFD3_k127_3169813_1 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000009824 213.0
HFD3_k127_3170948_0 Sugar (and other) transporter K08195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000061 530.0
HFD3_k127_3170948_1 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006581 412.0
HFD3_k127_3170948_10 sequence-specific DNA binding K01239,K02855,K07506,K18199 - 3.2.2.1,4.2.1.103 0.00000000000004554 74.0
HFD3_k127_3170948_2 Belongs to the MIP aquaporin (TC 1.A.8) family - - - 0.0000000000000000000000000000000000000000000000000000000000000003283 227.0
HFD3_k127_3170948_3 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000003612 170.0
HFD3_k127_3170948_4 - - - - 0.000000000000000000000000000000000000000000005767 173.0
HFD3_k127_3170948_5 Glyoxalase-like domain K01759 GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0050896 4.4.1.5 0.00000000000000000000000000000000000000000007217 164.0
HFD3_k127_3170948_6 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000000000000000000000000000000001014 162.0
HFD3_k127_3170948_7 Carboxylesterase family - - - 0.0000000000000000000000000000000000000001247 162.0
HFD3_k127_3170948_8 SnoaL-like domain K06893 - - 0.000000000000000000000000000007834 125.0
HFD3_k127_3170948_9 - - - - 0.00000000000000001486 92.0
HFD3_k127_3173792_0 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005002 595.0
HFD3_k127_3173792_1 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003393 284.0
HFD3_k127_3173792_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000298 196.0
HFD3_k127_3173792_3 2OG-Fe(II) oxygenase superfamily - - - 0.00000000000000000000000000000000000000000003583 164.0
HFD3_k127_3173792_4 - - - - 0.00000000000000000000000000001198 129.0
HFD3_k127_3173792_5 - - - - 0.000000000000000000000000000244 125.0
HFD3_k127_3173792_7 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.0000000000000006926 77.0
HFD3_k127_3173792_8 - - - - 0.0000000003247 66.0
HFD3_k127_3173792_9 Amidohydrolase family - - - 0.0000005201 52.0
HFD3_k127_3221764_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001401 275.0
HFD3_k127_3221764_1 - - - - 0.0000000000000000000000000000000000007963 152.0
HFD3_k127_3221764_2 - - - - 0.0000000000000000000000000000000004833 137.0
HFD3_k127_3227105_0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000000000000000000000000000000000000003335 182.0
HFD3_k127_3227105_1 - - - - 0.0000000000000000582 91.0
HFD3_k127_3227105_2 Pfam:N_methyl_2 K02456 - - 0.00000000000000008491 85.0
HFD3_k127_3227105_3 - - - - 0.000000000004727 74.0
HFD3_k127_3242539_0 amine dehydrogenase activity - - - 5.08e-288 960.0
HFD3_k127_3242539_1 oxidoreductase activity - - - 0.000000000000000000000000000000000000000000003511 191.0
HFD3_k127_3242539_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000005812 152.0
HFD3_k127_3242539_3 peptidase - - - 0.000000000000000000000000000002426 126.0
HFD3_k127_3242539_4 conserved repeat domain protein - - - 0.000000000000728 84.0
HFD3_k127_3242561_0 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003119 275.0
HFD3_k127_3243435_0 elongation factor G K02355 - - 2.292e-237 753.0
HFD3_k127_3243435_1 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 7.686e-203 644.0
HFD3_k127_3243435_10 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002627 352.0
HFD3_k127_3243435_11 Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 336.0
HFD3_k127_3243435_12 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003667 329.0
HFD3_k127_3243435_13 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000611 314.0
HFD3_k127_3243435_14 NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 310.0
HFD3_k127_3243435_15 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006128 283.0
HFD3_k127_3243435_16 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003602 271.0
HFD3_k127_3243435_17 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003014 273.0
HFD3_k127_3243435_18 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000003416 188.0
HFD3_k127_3243435_19 Glycosyltransferase family 9 (heptosyltransferase) K02849 - - 0.000000000000000000000000000000000000000004534 167.0
HFD3_k127_3243435_2 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 1.388e-194 629.0
HFD3_k127_3243435_20 surface antigen K07277 - - 0.00000000000000000000000000000000000000001343 174.0
HFD3_k127_3243435_21 von Willebrand factor, type A - - - 0.000000000000000000000000000000002116 142.0
HFD3_k127_3243435_22 Glycosyl transferase, family 2 K07011 - - 0.00000000000000000000000000000003804 136.0
HFD3_k127_3243435_23 Flavin reductase like domain - - - 0.000000000000000000000000000000655 132.0
HFD3_k127_3243435_24 Glycosyl transferases group 1 - - - 0.00000000000000000000000000002698 130.0
HFD3_k127_3243435_25 Putative restriction endonuclease - - - 0.000000000000000000000000002437 116.0
HFD3_k127_3243435_26 - - - - 0.0000000000000000000001239 103.0
HFD3_k127_3243435_27 methyltransferase - - - 0.0000000000000000000001547 108.0
HFD3_k127_3243435_29 Trm112p-like protein K09791 - - 0.00000000000000000004218 91.0
HFD3_k127_3243435_3 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 592.0
HFD3_k127_3243435_30 - - - - 0.000000000000000001626 85.0
HFD3_k127_3243435_33 chlorophyll binding - - - 0.0000002506 61.0
HFD3_k127_3243435_34 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000003243 53.0
HFD3_k127_3243435_4 Phosphate acyltransferases K00655,K01897 - 2.3.1.51,6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005731 576.0
HFD3_k127_3243435_5 Mismatch repair ATPase (MutS family) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003486 552.0
HFD3_k127_3243435_6 phosphorelay sensor kinase activity K07709,K07710 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 483.0
HFD3_k127_3243435_7 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003781 430.0
HFD3_k127_3243435_8 aminopeptidase K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007891 435.0
HFD3_k127_3243435_9 MFS_1 like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004489 416.0
HFD3_k127_3287490_0 metalloendopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 332.0
HFD3_k127_3287490_1 Domain of unknown function (DUF4139) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005812 298.0
HFD3_k127_3287490_3 - - - - 0.0000001097 58.0
HFD3_k127_3319429_0 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 5.418e-286 901.0
HFD3_k127_3364244_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 2.257e-225 727.0
HFD3_k127_3364244_1 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 521.0
HFD3_k127_3364244_2 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000001625 144.0
HFD3_k127_3364244_3 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000000733 140.0
HFD3_k127_3390935_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1238.0
HFD3_k127_3390935_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1034.0
HFD3_k127_3390935_10 AAA ATPase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004236 546.0
HFD3_k127_3390935_11 Arginosuccinate synthase K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 514.0
HFD3_k127_3390935_12 sequence-specific DNA binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 505.0
HFD3_k127_3390935_13 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 492.0
HFD3_k127_3390935_14 von Willebrand factor (vWF) type A domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 473.0
HFD3_k127_3390935_15 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008074 456.0
HFD3_k127_3390935_16 Putative modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 427.0
HFD3_k127_3390935_17 ABC transporter C-terminal domain K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 430.0
HFD3_k127_3390935_18 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000684 415.0
HFD3_k127_3390935_19 TIGRFAM argininosuccinate lyase K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 400.0
HFD3_k127_3390935_2 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.067e-312 994.0
HFD3_k127_3390935_20 Oxidoreductase molybdopterin binding domain K07147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004786 390.0
HFD3_k127_3390935_21 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005841 379.0
HFD3_k127_3390935_22 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 366.0
HFD3_k127_3390935_23 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 357.0
HFD3_k127_3390935_24 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004675 339.0
HFD3_k127_3390935_25 peptidyl-lysine modification to peptidyl-hypusine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007476 323.0
HFD3_k127_3390935_26 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 312.0
HFD3_k127_3390935_27 Cellulose biosynthesis protein BcsQ K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 309.0
HFD3_k127_3390935_28 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 289.0
HFD3_k127_3390935_29 tail specific protease K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005216 279.0
HFD3_k127_3390935_3 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.451e-306 959.0
HFD3_k127_3390935_30 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000001385 271.0
HFD3_k127_3390935_31 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009898 246.0
HFD3_k127_3390935_32 ParB-like nuclease domain K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003352 252.0
HFD3_k127_3390935_33 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0031224,GO:0031226,GO:0032940,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051205,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0061024,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 - 0.00000000000000000000000000000000000000000000000000000000000000000000005475 261.0
HFD3_k127_3390935_34 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000001854 242.0
HFD3_k127_3390935_35 TIGRFAM geranylgeranyl reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001144 251.0
HFD3_k127_3390935_36 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000002504 248.0
HFD3_k127_3390935_37 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.0000000000000000000000000000000000000000000000000000000000002493 225.0
HFD3_k127_3390935_38 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000004713 218.0
HFD3_k127_3390935_39 GDSL-like Lipase/Acylhydrolase - - - 0.00000000000000000000000000000000000000000000000000000001822 206.0
HFD3_k127_3390935_4 Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 1.389e-273 850.0
HFD3_k127_3390935_40 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000004164 216.0
HFD3_k127_3390935_41 dioxygenase of extradiol dioxygenase family K06991 - - 0.000000000000000000000000000000000000000000000000000000913 195.0
HFD3_k127_3390935_42 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000423 199.0
HFD3_k127_3390935_43 Protein conserved in bacteria K09984 - - 0.0000000000000000000000000000000000000000000000000003313 185.0
HFD3_k127_3390935_44 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.0000000000000000000000000000000000000000000000005034 185.0
HFD3_k127_3390935_45 5-formyltetrahydrofolate cyclo-ligase family - - - 0.000000000000000000000000000000000000000000000001318 180.0
HFD3_k127_3390935_46 - - - - 0.0000000000000000000000000000000000000000000000595 186.0
HFD3_k127_3390935_47 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.0000000000000000000000000000000000000000000005788 181.0
HFD3_k127_3390935_49 SurA N-terminal domain K03771 - 5.2.1.8 0.00000000000000000000000000000000000001389 157.0
HFD3_k127_3390935_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.1e-246 771.0
HFD3_k127_3390935_50 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950 - 2.7.6.3 0.0000000000000000000000000000000000002036 146.0
HFD3_k127_3390935_51 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000000003434 145.0
HFD3_k127_3390935_52 Penicillinase repressor - - - 0.000000000000000000000000000000000002327 143.0
HFD3_k127_3390935_53 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000000000002929 144.0
HFD3_k127_3390935_54 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00000000000000000000000000000000001236 139.0
HFD3_k127_3390935_55 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000318 136.0
HFD3_k127_3390935_56 PFAM Acetyltransferase (GNAT) family K00619 - 2.3.1.1 0.0000000000000000000000000000006589 130.0
HFD3_k127_3390935_57 - K01286 - 3.4.16.4 0.00000000000000000000000000002289 126.0
HFD3_k127_3390935_58 arginine binding K03402 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.00000000000000000000000001488 115.0
HFD3_k127_3390935_59 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000002938 104.0
HFD3_k127_3390935_6 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 4.185e-230 723.0
HFD3_k127_3390935_61 Pfam:N_methyl_2 - - - 0.0000000000000000004144 92.0
HFD3_k127_3390935_62 Polymer-forming cytoskeletal - - - 0.0000000000000000006438 91.0
HFD3_k127_3390935_63 S4 RNA-binding domain - GO:0008150,GO:0040007 - 0.0000000000000000168 86.0
HFD3_k127_3390935_64 TIGRFAM RNA polymerase sigma factor, FliA WhiG family K02405 - - 0.00000000000000002709 86.0
HFD3_k127_3390935_65 negative regulation of transcription, DNA-templated - - - 0.000000000000001225 82.0
HFD3_k127_3390935_66 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000002064 80.0
HFD3_k127_3390935_67 PFAM Abortive infection protein K07052 - - 0.00000000000004452 81.0
HFD3_k127_3390935_68 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000000004662 70.0
HFD3_k127_3390935_69 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.0000000000005641 76.0
HFD3_k127_3390935_7 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 1.219e-228 723.0
HFD3_k127_3390935_70 Protein of unknown function (DUF1062) - - - 0.00000000008395 68.0
HFD3_k127_3390935_71 Serine aminopeptidase, S33 - - - 0.00000001196 67.0
HFD3_k127_3390935_8 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004732 610.0
HFD3_k127_3390935_9 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003372 569.0
HFD3_k127_3404423_0 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 515.0
HFD3_k127_3404423_1 family UPF0324 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 481.0
HFD3_k127_3404423_10 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008515 272.0
HFD3_k127_3404423_11 TLC ATP/ADP transporter K03301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004634 289.0
HFD3_k127_3404423_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006057 277.0
HFD3_k127_3404423_13 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000002367 263.0
HFD3_k127_3404423_14 cytochrome - - - 0.000000000000000000000000000000000000000000000000000000000000000000167 243.0
HFD3_k127_3404423_15 Histidine kinase-, DNA gyrase B-, and HSP90-like - - - 0.00000000000000000000000000000000000000000000000000000000000000003193 236.0
HFD3_k127_3404423_16 Drug metabolite transporter - - - 0.00000000000000000000000000000000000000000000000000000000000008246 226.0
HFD3_k127_3404423_17 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000000000000000000000000000000008632 224.0
HFD3_k127_3404423_18 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02527,K02841,K02843,K12982 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000001149 207.0
HFD3_k127_3404423_19 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000009255 199.0
HFD3_k127_3404423_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 466.0
HFD3_k127_3404423_20 Polynucleotide kinase 3 phosphatase K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000000004581 186.0
HFD3_k127_3404423_21 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.0000000000000000000000000000000000000000000001369 173.0
HFD3_k127_3404423_22 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000004432 151.0
HFD3_k127_3404423_23 Preprotein translocase SecG subunit K03075 - - 0.0000000000000000002668 93.0
HFD3_k127_3404423_24 - - - - 0.0000000000000004799 85.0
HFD3_k127_3404423_25 Surface antigen - - - 0.0000000001326 74.0
HFD3_k127_3404423_26 2OG-Fe(II) oxygenase superfamily - - - 0.0000000005575 66.0
HFD3_k127_3404423_27 Transcriptional regulator crp fnr family K10914 - - 0.00007111 51.0
HFD3_k127_3404423_3 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009323 460.0
HFD3_k127_3404423_4 Trypsin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006809 387.0
HFD3_k127_3404423_5 ATP ADP translocase K03301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000843 348.0
HFD3_k127_3404423_6 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 318.0
HFD3_k127_3404423_7 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 301.0
HFD3_k127_3404423_8 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 307.0
HFD3_k127_3404423_9 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008955,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0042546,GO:0043164,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000557 284.0
HFD3_k127_34163_0 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008478 511.0
HFD3_k127_34163_1 Belongs to the peptidase M50B family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 466.0
HFD3_k127_34163_2 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 301.0
HFD3_k127_34163_3 Glyoxalase-like domain K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000001514 222.0
HFD3_k127_34163_4 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000008137 101.0
HFD3_k127_3417222_0 Glycosyl transferase, family 2 K21349 - 2.4.1.268 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 498.0
HFD3_k127_3417222_1 transferase activity, transferring glycosyl groups K13693 - 2.4.1.266 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 483.0
HFD3_k127_3417222_10 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.00000000000000000000000005632 115.0
HFD3_k127_3417222_11 PFAM Conserved TM helix repeat-containing protein - - - 0.000000000000000004716 93.0
HFD3_k127_3417222_13 Sugar (and other) transporter - - - 0.000285 48.0
HFD3_k127_3417222_2 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004123 463.0
HFD3_k127_3417222_3 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005614 429.0
HFD3_k127_3417222_4 mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 290.0
HFD3_k127_3417222_5 UvrD-like helicase C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006396 306.0
HFD3_k127_3417222_6 heat shock protein DnaJ K05516 - - 0.000000000000000000000000000000000000000000000000000002168 197.0
HFD3_k127_3417222_7 haloacid dehalogenase-like hydrolase K05947,K07026 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050897 2.4.1.217,3.1.3.70 0.00000000000000000000000000000000000000000000000000008985 195.0
HFD3_k127_3417222_8 response regulator K07685 - - 0.000000000000000000000000000000000000000773 160.0
HFD3_k127_3417222_9 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000004479 144.0
HFD3_k127_3424713_0 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 522.0
HFD3_k127_3424713_1 Trehalose utilisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006763 283.0
HFD3_k127_3455311_0 Transketolase, pyrimidine binding domain K00167 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005218 515.0
HFD3_k127_3455311_1 Dehydrogenase E1 component K00161 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 374.0
HFD3_k127_3455311_2 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000001472 233.0
HFD3_k127_3455311_3 e3 binding domain K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000003402 168.0
HFD3_k127_3455311_4 - - - - 0.000000000000000002347 91.0
HFD3_k127_3467826_0 WD40 domain protein beta Propeller K12132 - 2.7.11.1 4.341e-211 688.0
HFD3_k127_3467826_1 ATP dependent DNA ligase C terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 572.0
HFD3_k127_3467826_2 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003875 521.0
HFD3_k127_3467826_3 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.000000000000000000000000000000000000000000000000000004421 196.0
HFD3_k127_3467826_4 PFAM Polyketide cyclase dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000001188 163.0
HFD3_k127_3467826_5 - - - - 0.000000000000001256 83.0
HFD3_k127_3519867_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1371.0
HFD3_k127_3519867_1 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1156.0
HFD3_k127_3519867_10 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 417.0
HFD3_k127_3519867_11 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008186 416.0
HFD3_k127_3519867_12 Oxidoreductase molybdopterin binding domain K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007429 383.0
HFD3_k127_3519867_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 376.0
HFD3_k127_3519867_14 synthetase, class II (G H P K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 374.0
HFD3_k127_3519867_15 InterPro IPR010496 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 366.0
HFD3_k127_3519867_16 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 348.0
HFD3_k127_3519867_17 Conserved hypothetical ATP binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003985 342.0
HFD3_k127_3519867_18 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 325.0
HFD3_k127_3519867_19 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005535 306.0
HFD3_k127_3519867_2 TonB-dependent receptor - - - 0.0 1058.0
HFD3_k127_3519867_20 CDP-alcohol phosphatidyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004281 268.0
HFD3_k127_3519867_21 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000001166 237.0
HFD3_k127_3519867_22 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.000000000000000000000000000000000000000000000000000000000000000002305 232.0
HFD3_k127_3519867_23 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000002242 230.0
HFD3_k127_3519867_24 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000001988 227.0
HFD3_k127_3519867_25 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000000000000001957 220.0
HFD3_k127_3519867_26 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000000000004038 218.0
HFD3_k127_3519867_27 permease - - - 0.000000000000000000000000000000000000000000000000000000006551 212.0
HFD3_k127_3519867_28 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000002124 196.0
HFD3_k127_3519867_29 Disulphide isomerase - - - 0.00000000000000000000000000000000000000000000000000007244 189.0
HFD3_k127_3519867_3 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.11e-312 977.0
HFD3_k127_3519867_30 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000002307 184.0
HFD3_k127_3519867_31 RNA polymerase sigma factor K03088 - - 0.000000000000000000000000000000000000000000003323 169.0
HFD3_k127_3519867_32 - - - - 0.000000000000000000000000000000000003645 145.0
HFD3_k127_3519867_33 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000181 142.0
HFD3_k127_3519867_34 RNA recognition motif - - - 0.0000000000000000000000001151 108.0
HFD3_k127_3519867_35 regulation of translation K03530 - - 0.000000000000000000000000573 108.0
HFD3_k127_3519867_36 GtrA-like protein - - - 0.000000000000000000000001447 107.0
HFD3_k127_3519867_37 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000008609 94.0
HFD3_k127_3519867_38 NUDIX domain - - - 0.000000000000000000355 91.0
HFD3_k127_3519867_39 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000123 86.0
HFD3_k127_3519867_4 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 4.537e-203 648.0
HFD3_k127_3519867_40 - - - - 0.0000000000000000471 88.0
HFD3_k127_3519867_41 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000002642 81.0
HFD3_k127_3519867_42 Putative zinc-finger - - - 0.00000000004052 71.0
HFD3_k127_3519867_43 - - - - 0.000000004934 63.0
HFD3_k127_3519867_44 ATP-independent chaperone mediated protein folding - - - 0.000009334 55.0
HFD3_k127_3519867_45 - - - - 0.00001278 57.0
HFD3_k127_3519867_46 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0001727 48.0
HFD3_k127_3519867_47 - - - - 0.0005655 50.0
HFD3_k127_3519867_5 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008324 588.0
HFD3_k127_3519867_6 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 530.0
HFD3_k127_3519867_7 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 483.0
HFD3_k127_3519867_8 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004946 469.0
HFD3_k127_3519867_9 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 429.0
HFD3_k127_3574229_0 Carboxypeptidase regulatory-like domain - - - 0.0 1066.0
HFD3_k127_3574229_1 oxidoreductase activity - - - 9.064e-249 798.0
HFD3_k127_3574229_2 Trehalose utilisation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003853 409.0
HFD3_k127_3574229_3 Peptidase M56, BlaR1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006761 365.0
HFD3_k127_3574229_4 PQQ-like domain K00114,K20937 - 1.1.2.8,1.1.5.11 0.0000000000000000000000000000000000000000000000000000000000001784 222.0
HFD3_k127_3574229_5 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000000000000000000000002533 176.0
HFD3_k127_3604659_0 Protein of unknown function (DUF1800) - - - 1.35e-210 672.0
HFD3_k127_3604659_1 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 614.0
HFD3_k127_3604659_10 sugar transferase K00996 - 2.7.8.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 300.0
HFD3_k127_3604659_11 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002935 282.0
HFD3_k127_3604659_12 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000004033 226.0
HFD3_k127_3604659_13 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000000000000000000000007242 201.0
HFD3_k127_3604659_14 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000008616 196.0
HFD3_k127_3604659_15 methyltransferase K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000421 180.0
HFD3_k127_3604659_16 domain protein K14194 - - 0.000000000000000000000000000000000000000000000007083 193.0
HFD3_k127_3604659_17 -O-antigen K02847,K13009 - - 0.00000000000000000000000000000000000000179 164.0
HFD3_k127_3604659_18 negative regulation of transcription, DNA-templated - - - 0.00000000000000000000000000000000002562 138.0
HFD3_k127_3604659_19 Uncharacterised nucleotidyltransferase - - - 0.0000000000000000000000000000000000651 149.0
HFD3_k127_3604659_2 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 611.0
HFD3_k127_3604659_20 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000002366 128.0
HFD3_k127_3604659_21 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000005484 134.0
HFD3_k127_3604659_22 Polysaccharide biosynthesis protein - - - 0.00000000000000000005817 104.0
HFD3_k127_3604659_23 PFAM ABC transporter K01990 - - 0.000000000000000004608 87.0
HFD3_k127_3604659_24 1,4-alpha-glucan branching enzyme activity K00700 - 2.4.1.18 0.00000000000000002753 89.0
HFD3_k127_3604659_25 Methyltransferase FkbM domain - - - 0.0000000000000005611 88.0
HFD3_k127_3604659_26 -O-antigen - - - 0.000000000000009205 87.0
HFD3_k127_3604659_27 PFAM lipopolysaccharide biosynthesis - - - 0.000000000007117 78.0
HFD3_k127_3604659_28 ATP synthesis coupled proton transport K02109 - - 0.00000000002815 72.0
HFD3_k127_3604659_29 efflux transmembrane transporter activity - - - 0.0000002421 59.0
HFD3_k127_3604659_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008005 556.0
HFD3_k127_3604659_30 Belongs to the glycosyl hydrolase 13 family - - - 0.000001533 60.0
HFD3_k127_3604659_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 440.0
HFD3_k127_3604659_5 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005011 389.0
HFD3_k127_3604659_6 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 344.0
HFD3_k127_3604659_8 Glycosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004796 327.0
HFD3_k127_3604659_9 FtsZ-dependent cytokinesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006753 330.0
HFD3_k127_361655_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 1.306e-264 832.0
HFD3_k127_361655_1 PFAM aminotransferase class V - GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001827 272.0
HFD3_k127_361655_2 - - - - 0.00000000000000000000000000000000000372 149.0
HFD3_k127_361655_3 Protein of unknown function (DUF1161) - - - 0.000000000001702 73.0
HFD3_k127_361655_4 Acetyltransferase (GNAT) family - - - 0.0000000001594 68.0
HFD3_k127_36319_0 - - - - 0.000000000000000000000000000000000000000000005873 176.0
HFD3_k127_36319_2 domain protein - - - 0.0000000000000003883 92.0
HFD3_k127_36319_3 protocatechuate 3,4-dioxygenase - - - 0.00000000001405 78.0
HFD3_k127_36319_4 - - - - 0.0000000001785 68.0
HFD3_k127_3639204_0 Amidase K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 538.0
HFD3_k127_3639204_1 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004716 360.0
HFD3_k127_3639204_2 sequence-specific DNA binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 346.0
HFD3_k127_3639204_3 LysM domain - - - 0.0000000000000000000000000000000000000000000005827 171.0
HFD3_k127_3639204_4 thiolester hydrolase activity K06889 - - 0.000000000000000000000000000000000000000000003239 174.0
HFD3_k127_3639204_5 DinB superfamily K07552 - - 0.000000000000000000000000000000000000000005289 161.0
HFD3_k127_3639204_6 LysM domain - - - 0.000000001353 59.0
HFD3_k127_3639204_7 Peptidase M14, carboxypeptidase A - - - 0.000009607 47.0
HFD3_k127_3663812_0 class II (D K K01893 - 6.1.1.22 6.279e-196 619.0
HFD3_k127_3663812_1 Cytochrome D1 heme domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 520.0
HFD3_k127_3663812_2 Arginase family K01476 - 3.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000271 372.0
HFD3_k127_3663812_3 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000002589 231.0
HFD3_k127_3663812_4 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000000000006575 203.0
HFD3_k127_3663812_5 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000002101 208.0
HFD3_k127_3663812_6 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000006352 134.0
HFD3_k127_3724908_0 HupE / UreJ protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004216 436.0
HFD3_k127_3724908_1 response to copper ion K01187,K16915 - 3.2.1.20 0.00000000000000000000000000000000000003249 146.0
HFD3_k127_3780082_0 TonB-dependent Receptor Plug Domain - - - 1.583e-220 725.0
HFD3_k127_3780082_1 Glycine D-amino acid oxidase (deaminating) - - - 3.233e-194 617.0
HFD3_k127_3780082_2 Belongs to the heat shock protein 70 family K04046 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 446.0
HFD3_k127_3780082_3 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 346.0
HFD3_k127_3780082_4 TIGRFAM PQQ-dependent dehydrogenase, methanol ethanol family K00114 - 1.1.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006035 333.0
HFD3_k127_3780082_5 Protein of unknown function (DUF3667) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001211 274.0
HFD3_k127_3780082_6 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.0000000000000001495 81.0
HFD3_k127_3780082_7 HNH endonuclease - - - 0.0007044 46.0
HFD3_k127_3837063_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 516.0
HFD3_k127_3837063_1 Binding-protein-dependent transport system inner membrane component K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 510.0
HFD3_k127_3837063_10 ZIP Zinc transporter K07238,K16267 - - 0.0000000000000000000000000000000000000000000000000000000000000000001039 238.0
HFD3_k127_3837063_11 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000175 234.0
HFD3_k127_3837063_12 Domain of unknown function (DUF4416) - - - 0.00000000000000000000000000000000000000000000007315 175.0
HFD3_k127_3837063_13 Belongs to the MraZ family K03925 - - 0.00000000000000000000000000000000000000000001272 166.0
HFD3_k127_3837063_14 Histidine triad (HIT) protein K02503 - - 0.00000000000000000000000000000000000000000009485 161.0
HFD3_k127_3837063_15 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) K11711 - 2.7.13.3 0.0000000000000000000000000000001703 135.0
HFD3_k127_3837063_16 CHAT domain - - - 0.00000000000000000000000000005794 136.0
HFD3_k127_3837063_17 PFAM Iron sulphur-containing domain, CDGSH-type - - - 0.0000000000000000000003775 98.0
HFD3_k127_3837063_18 Belongs to the ILVD EDD family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576 4.2.1.9 0.0000000000000000004842 102.0
HFD3_k127_3837063_19 RNA polymerase-binding protein DksA K06204 - - 0.0000000000000001156 85.0
HFD3_k127_3837063_2 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007372 508.0
HFD3_k127_3837063_20 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.000000000000006045 76.0
HFD3_k127_3837063_21 Tetratricopeptide repeat - - - 0.0000001167 63.0
HFD3_k127_3837063_22 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0002469 51.0
HFD3_k127_3837063_3 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 483.0
HFD3_k127_3837063_4 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 437.0
HFD3_k127_3837063_5 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 398.0
HFD3_k127_3837063_6 GTP binding K06942 GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0043021,GO:0043022,GO:0043023,GO:0043086,GO:0044092,GO:0044424,GO:0044464,GO:0044877,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0098772 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 301.0
HFD3_k127_3837063_7 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009496 295.0
HFD3_k127_3837063_8 TOBE domain K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002 278.0
HFD3_k127_3837063_9 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000008384 267.0
HFD3_k127_3853484_0 ATP-dependent peptidase activity K01338,K04076,K04770 - 3.4.21.53 3.077e-260 825.0
HFD3_k127_3853484_1 PFAM Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002978 235.0
HFD3_k127_3853484_2 Belongs to the universal stress protein A family - - - 0.000000000000000000000000005799 121.0
HFD3_k127_3890336_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.032e-318 992.0
HFD3_k127_3890336_1 Participates in both transcription termination and antitermination K02600 - - 1.534e-213 666.0
HFD3_k127_3890336_2 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000004518 197.0
HFD3_k127_3890336_3 branched-chain-amino-acid transaminase activity K00824 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016769,GO:0019478,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046416,GO:0046437,GO:0047810,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.6.1.21 0.000000000000000000000009769 102.0
HFD3_k127_3901361_0 Cys/Met metabolism PLP-dependent enzyme K10907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004004 533.0
HFD3_k127_3901361_1 Trypsin K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006518 347.0
HFD3_k127_3901361_2 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000002307 259.0
HFD3_k127_3901361_3 Biotin/lipoate A/B protein ligase family K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.0000000000000000000000000000000000000000002472 167.0
HFD3_k127_3901361_4 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0017076,GO:0030234,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0071496,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.0000000000000000000000000000001204 131.0
HFD3_k127_3901361_5 prohibitin homologues K04087 - - 0.00001298 58.0
HFD3_k127_3932168_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 3.719e-210 666.0
HFD3_k127_3932168_1 COG0451 Nucleoside-diphosphate-sugar epimerases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001419 276.0
HFD3_k127_3932168_2 - - - - 0.0000000000000000000000000001182 122.0
HFD3_k127_3932168_3 Cytochrome c K00117,K02030,K17760,K19713 - 1.1.5.2,1.1.9.1,1.8.2.2 0.0000000000000000005298 100.0
HFD3_k127_3963690_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 2.957e-250 781.0
HFD3_k127_3963690_1 PFAM peptidase U62 modulator of DNA gyrase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009068 581.0
HFD3_k127_3963690_10 - - - - 0.000001487 57.0
HFD3_k127_3963690_2 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004071 344.0
HFD3_k127_3963690_3 Putative modulator of DNA gyrase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005529 304.0
HFD3_k127_3963690_4 A G-specific K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003034 269.0
HFD3_k127_3963690_5 PFAM von Willebrand factor type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000553 247.0
HFD3_k127_3963690_6 Cytidylyltransferase K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000007313 241.0
HFD3_k127_3963690_7 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000000000000000000000000000000000004921 240.0
HFD3_k127_3963690_8 Radical SAM K22227 - - 0.00000000000000000000000000000000001761 149.0
HFD3_k127_3963690_9 PFAM von Willebrand factor type A K07114 - - 0.000000000000000000000001871 114.0
HFD3_k127_3965991_0 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM-like protein K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000006087 227.0
HFD3_k127_3965991_1 Psort location Cytoplasmic, score K03518 - 1.2.5.3 0.0000000000000000000002056 104.0
HFD3_k127_3965991_2 AMP-binding enzyme K04110 - 6.2.1.25 0.0000000000000000004385 89.0
HFD3_k127_3970496_0 L-lactate permease K03303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 503.0
HFD3_k127_3970496_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 357.0
HFD3_k127_3970496_2 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000003996 141.0
HFD3_k127_3970726_0 DNA topological change K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 607.0
HFD3_k127_3970726_1 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 324.0
HFD3_k127_3970726_2 protein-glutamate O-methyltransferase activity K00575,K03408,K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002815 284.0
HFD3_k127_3970726_3 Ankyrin repeats (many copies) - - - 0.00000000000000000000000000000000000000000000000000000001671 220.0
HFD3_k127_3970726_5 Helix-hairpin-helix motif K02237 - - 0.000000312 59.0
HFD3_k127_3970726_6 - - - - 0.0000003744 58.0
HFD3_k127_3974291_0 Insulinase (Peptidase family M16) K07263 - - 2.357e-275 875.0
HFD3_k127_3974291_1 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003392 398.0
HFD3_k127_3974291_10 Protein of unknown function (DUF541) K09807 - - 0.00000000000000000000000000004695 125.0
HFD3_k127_3974291_11 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000006188 126.0
HFD3_k127_3974291_12 Protein of unknown function (DUF971) K03593 - - 0.000000000000000000000000008038 112.0
HFD3_k127_3974291_14 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.00000000000000000009967 95.0
HFD3_k127_3974291_2 iron ion homeostasis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 413.0
HFD3_k127_3974291_3 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 379.0
HFD3_k127_3974291_4 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000008029 224.0
HFD3_k127_3974291_5 alkylbase DNA N-glycosylase activity K03652 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000003652 216.0
HFD3_k127_3974291_6 Calcium/calmodulin dependent protein kinase II association domain - - - 0.00000000000000000000000000000000000000000000001298 176.0
HFD3_k127_3974291_7 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.00000000000000000000000000000000000000006504 158.0
HFD3_k127_3974291_8 - - - - 0.0000000000000000000000000000000000000001175 159.0
HFD3_k127_3974291_9 ATP-dependent Clp protease adaptor protein ClpS K06891 - - 0.0000000000000000000000000000002472 126.0
HFD3_k127_3982891_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 1.557e-314 974.0
HFD3_k127_3982891_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 595.0
HFD3_k127_3982891_2 Peptidase M3A and M3B thimet oligopeptidase F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 497.0
HFD3_k127_3982891_3 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 427.0
HFD3_k127_3982891_4 PFAM AMP-dependent synthetase and ligase K01897,K18661 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 361.0
HFD3_k127_3982891_5 Esterase-like activity of phytase K03929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000184 283.0
HFD3_k127_3982891_6 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001854 263.0
HFD3_k127_3982891_7 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000008089 228.0
HFD3_k127_3982891_8 4Fe-4S dicluster domain K05524 - - 0.000000000000000000000000000000000009934 138.0
HFD3_k127_3983008_0 Biotin-lipoyl like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006319 353.0
HFD3_k127_3983008_1 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 336.0
HFD3_k127_3983008_2 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 289.0
HFD3_k127_3983008_3 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001997 273.0
HFD3_k127_3983008_4 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000002607 237.0
HFD3_k127_3983008_5 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000002843 169.0
HFD3_k127_3983008_6 Domain of unknown function (DUF1330) - - - 0.000000000000000000000000007213 114.0
HFD3_k127_3983008_7 response to cobalt ion - - - 0.00000000000001954 80.0
HFD3_k127_3983008_8 domain protein K14194 - - 0.00000000008558 74.0
HFD3_k127_3986099_0 glutamine synthetase K01915 - 6.3.1.2 2.451e-247 769.0
HFD3_k127_3986099_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 4.706e-228 724.0
HFD3_k127_3986099_10 - - - - 0.000000000007014 74.0
HFD3_k127_3986099_2 Peptidase M50 K16922 - - 1.453e-224 716.0
HFD3_k127_3986099_3 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004232 516.0
HFD3_k127_3986099_4 Gkycosyl transferase family 4 group - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 428.0
HFD3_k127_3986099_5 Xylose isomerase-like TIM barrel K01816 - 5.3.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000001339 254.0
HFD3_k127_3986099_6 Outer membrane efflux protein K12340 - - 0.0000000000000000000000000000000000000002364 170.0
HFD3_k127_3986099_7 PQQ-like domain K00114 - 1.1.2.8 0.000000000000000000000000000004017 124.0
HFD3_k127_3986099_8 Protein of unknown function (DUF3467) - - - 0.00000000000000000000000000001081 122.0
HFD3_k127_3986099_9 Biotin-lipoyl like - - - 0.0000000000000002082 89.0
HFD3_k127_4011079_0 efflux transmembrane transporter activity - - - 4.577e-259 829.0
HFD3_k127_4011079_1 DNA topological change K03168 - 5.99.1.2 4.065e-209 676.0
HFD3_k127_4011079_10 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001651 316.0
HFD3_k127_4011079_11 response to abiotic stimulus K06867 - - 0.000000000000000000000000000000000000000000000000000000000000000002078 247.0
HFD3_k127_4011079_12 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000005326 201.0
HFD3_k127_4011079_13 PFAM lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000002181 177.0
HFD3_k127_4011079_14 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000000000171 149.0
HFD3_k127_4011079_15 - - - - 0.00000000000000000000000000000000000007583 152.0
HFD3_k127_4011079_16 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000000003878 131.0
HFD3_k127_4011079_17 phospholipase Carboxylesterase - - - 0.0000000000000000000000000000005543 136.0
HFD3_k127_4011079_19 PFAM DinB family protein - - - 0.00000000000000000000000000001122 124.0
HFD3_k127_4011079_2 Parallel beta-helix repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 562.0
HFD3_k127_4011079_20 Glycosyl hydrolase family 10 K01181 - 3.2.1.8 0.0000000000000000001101 97.0
HFD3_k127_4011079_21 MacB-like periplasmic core domain - - - 0.00000000000005931 80.0
HFD3_k127_4011079_22 FCD - - - 0.0000000000003517 79.0
HFD3_k127_4011079_25 Psort location Extracellular, score K07126,K15475 - - 0.000002907 56.0
HFD3_k127_4011079_3 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000574 533.0
HFD3_k127_4011079_4 FAD binding domain K00481 - 1.14.13.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002771 502.0
HFD3_k127_4011079_5 Tannase and feruloyl esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 466.0
HFD3_k127_4011079_6 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002811 452.0
HFD3_k127_4011079_7 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 368.0
HFD3_k127_4011079_8 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008782 335.0
HFD3_k127_4011079_9 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009566 329.0
HFD3_k127_4016508_0 PFAM Nucleotidyl transferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 392.0
HFD3_k127_4016508_1 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000002215 256.0
HFD3_k127_4016508_2 phosphatase activity K07025 - - 0.0000000000000000000000000000000000000000000000000007457 192.0
HFD3_k127_4016508_3 hydrolase (HAD superfamily) K01560,K07025,K08723 - 3.1.3.5,3.8.1.2 0.000000000000000000000000000000000000000000000007419 181.0
HFD3_k127_4016508_4 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000001918 174.0
HFD3_k127_4016508_5 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000472 135.0
HFD3_k127_4017595_0 geranylgeranyl reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000763 432.0
HFD3_k127_4017595_1 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 393.0
HFD3_k127_4017595_10 Membrane protein implicated in regulation of membrane protease activity - - - 0.00000000009182 70.0
HFD3_k127_4017595_11 COG3209 Rhs family protein - - - 0.0000004905 61.0
HFD3_k127_4017595_12 - - - - 0.00002389 53.0
HFD3_k127_4017595_13 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0001409 46.0
HFD3_k127_4017595_2 Flotillin K07192 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 389.0
HFD3_k127_4017595_3 Protein of unknown function (DUF1207) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 314.0
HFD3_k127_4017595_4 Isoprenylcysteine carboxyl methyltransferase (ICMT) family K00587 - 2.1.1.100 0.00000000000000000000000000000000000000000003081 168.0
HFD3_k127_4017595_5 - - - - 0.00000000000000000000000000000000000000000003345 177.0
HFD3_k127_4017595_6 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000000001016 163.0
HFD3_k127_4017595_7 Putative restriction endonuclease - - - 0.00000000000000000000000000000000000000002592 160.0
HFD3_k127_4017595_8 AAA domain - - - 0.0000000000000000000000000001753 121.0
HFD3_k127_4017595_9 - - - - 0.0000000000000004381 83.0
HFD3_k127_4037080_0 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 1.107e-226 723.0
HFD3_k127_4037080_1 PQQ-like domain K05889 - 1.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005267 435.0
HFD3_k127_4037080_2 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005662 314.0
HFD3_k127_4037080_3 COG3209 Rhs family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001703 293.0
HFD3_k127_4037080_4 RHS Repeat - - - 0.000000000000000000000000000000000000000000001411 189.0
HFD3_k127_4037080_5 TIGRFAM intracellular protease, PfpI family K05520 - 3.5.1.124 0.00000000000000000000000000202 118.0
HFD3_k127_4037080_7 Starch/carbohydrate-binding module (family 53) - - - 0.000003267 61.0
HFD3_k127_403826_0 isoleucyl-tRNA aminoacylation K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 0.0 1207.0
HFD3_k127_403826_1 Ribosomal protein S1 K02945 - - 5.917e-217 693.0
HFD3_k127_403826_10 Protein of unknown function (DUF1385) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002765 287.0
HFD3_k127_403826_11 Protein of unknown function (DUF2817) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006166 289.0
HFD3_k127_403826_12 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000006338 271.0
HFD3_k127_403826_13 RES - - - 0.00000000000000000000000000000000000000000000000000000000000000000000278 243.0
HFD3_k127_403826_14 gluconolactonase activity K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000008841 243.0
HFD3_k127_403826_15 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000007843 229.0
HFD3_k127_403826_16 TIGRFAM TonB family protein K03832 - - 0.000000000000000000000000000000000000000000000000000007116 203.0
HFD3_k127_403826_17 Protein of unknown function (DUF2384) - - - 0.00000000000000000000000000000000000000000000003964 173.0
HFD3_k127_403826_18 Signal peptidase (SPase) II K03101 - 3.4.23.36 0.000000000000000000000000000000001098 136.0
HFD3_k127_403826_19 - - - - 0.00000000000000000000000000002079 128.0
HFD3_k127_403826_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 509.0
HFD3_k127_403826_20 Peptidase family M1 domain - - - 0.00000000000000000000000000007307 133.0
HFD3_k127_403826_21 Binds the 23S rRNA K02909 - - 0.00000000000000000000000005552 111.0
HFD3_k127_403826_22 - - - - 0.0000000000000000000000009251 109.0
HFD3_k127_403826_23 - - - - 0.0000000000000000005184 88.0
HFD3_k127_403826_24 Tetratricopeptide repeat - - - 0.00000000000001103 86.0
HFD3_k127_403826_26 - - - - 0.000001027 55.0
HFD3_k127_403826_3 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 487.0
HFD3_k127_403826_4 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005742 484.0
HFD3_k127_403826_5 C-terminal, D2-small domain, of ClpB protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003811 433.0
HFD3_k127_403826_6 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 433.0
HFD3_k127_403826_7 RQC K03654 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348 435.0
HFD3_k127_403826_8 Dehydrogenase K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009987 374.0
HFD3_k127_403826_9 PFAM peptidase S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 302.0
HFD3_k127_4044317_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 4.708e-206 671.0
HFD3_k127_4044317_1 transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 512.0
HFD3_k127_4044317_10 - - - - 0.000000000000000000000005633 107.0
HFD3_k127_4044317_11 - - - - 0.0000000000000001211 90.0
HFD3_k127_4044317_12 Two component transcriptional regulator, winged helix family K02483,K07667 - - 0.00000000000003324 72.0
HFD3_k127_4044317_13 - - - - 0.00005104 51.0
HFD3_k127_4044317_3 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 316.0
HFD3_k127_4044317_4 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000000000000000000000000000000000000000004921 209.0
HFD3_k127_4044317_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000004183 182.0
HFD3_k127_4044317_8 - - - - 0.000000000000000000000000000000003703 140.0
HFD3_k127_4044317_9 nucleic acid-binding protein, contains PIN domain K07065 - - 0.000000000000000000000000000001107 127.0
HFD3_k127_405054_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1066.0
HFD3_k127_405054_1 PFAM 3-carboxy-cis,cis-muconate lactonizing enzyme K01317 - 3.4.21.10 0.000000000000000000000000000000000000000000000000000003452 221.0
HFD3_k127_405054_2 PFAM Cache type 2 domain protein - - - 0.00000000001525 69.0
HFD3_k127_4090389_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378,K13380 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004222 570.0
HFD3_k127_4090389_1 nitrite transmembrane transporter activity K08177 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 533.0
HFD3_k127_4090389_2 PQQ-like domain K00117 - 1.1.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 315.0
HFD3_k127_4090389_3 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000009921 159.0
HFD3_k127_4090389_4 Universal stress protein family - - - 0.00000000000000000000000488 115.0
HFD3_k127_4090389_5 von Willebrand factor, type A - - - 0.00000000052 71.0
HFD3_k127_4090389_6 YtxH-like protein - - - 0.0006363 46.0
HFD3_k127_4104960_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002726 520.0
HFD3_k127_4104960_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004785 295.0
HFD3_k127_4104960_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000235 237.0
HFD3_k127_4104960_3 ASCH - - - 0.000000000000000000000000000000000000000000002622 165.0
HFD3_k127_4104960_4 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000000000000191 141.0
HFD3_k127_4104960_5 Sigma-70 region 2 K03088 - - 0.000000000724 63.0
HFD3_k127_4114764_0 SMART metal-dependent phosphohydrolase, HD K06885 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008067 297.0
HFD3_k127_4114764_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000457 140.0
HFD3_k127_4114764_2 Thioredoxin-like K02199 - - 0.000000000000000000000000001068 118.0
HFD3_k127_4114764_3 Belongs to the Fur family K03711 - - 0.000000000000000000003704 104.0
HFD3_k127_4114764_4 PFAM Xanthine uracil vitamin C permease K06901 - - 0.0000001656 58.0
HFD3_k127_4114764_5 - - - - 0.0000535 54.0
HFD3_k127_4119709_0 MlaD protein K06192 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 312.0
HFD3_k127_4119709_1 Paraquat-inducible protein A K03808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001782 273.0
HFD3_k127_4119709_2 paraquat-inducible protein A K03808 - - 0.0000000000000000000000000000000000000000000000000000000000001836 219.0
HFD3_k127_4120143_0 Phosphate acyltransferases K01897,K05939 - 2.3.1.40,6.2.1.20,6.2.1.3 0.0 1303.0
HFD3_k127_4120143_1 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002465 521.0
HFD3_k127_4120143_2 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001693 279.0
HFD3_k127_4124745_0 NADH dehydrogenase (ubiquinone) activity K14089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 398.0
HFD3_k127_4124745_1 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 332.0
HFD3_k127_4124745_2 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002597 278.0
HFD3_k127_4124745_3 Ca-dependent carbohydrate-binding module xylan-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002763 248.0
HFD3_k127_4135975_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 3.981e-210 668.0
HFD3_k127_4135975_1 Putative glutamine amidotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007161 451.0
HFD3_k127_4135975_10 phosphatase activity K01560,K07025,K20866,K21063 GO:0003674,GO:0003824,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042578,GO:0042726,GO:0042727,GO:0043726,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.1.3.10,3.1.3.104,3.8.1.2 0.0000000000000000000000000000002467 130.0
HFD3_k127_4135975_11 Smr domain - - - 0.00000000000000000000000000001289 126.0
HFD3_k127_4135975_12 Hfq protein K03666 - - 0.000000000000000009459 89.0
HFD3_k127_4135975_13 Pilus assembly protein PilX K02673 - - 0.000000000001169 79.0
HFD3_k127_4135975_2 Tetratricopeptide repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006173 429.0
HFD3_k127_4135975_3 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007293 402.0
HFD3_k127_4135975_4 nuclear chromosome segregation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000479 389.0
HFD3_k127_4135975_5 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005941 285.0
HFD3_k127_4135975_6 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000004741 248.0
HFD3_k127_4135975_7 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000007693 181.0
HFD3_k127_4135975_8 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000009711 172.0
HFD3_k127_4135975_9 B-1 B cell differentiation - - - 0.000000000000000000000000000000000001238 152.0
HFD3_k127_4165971_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 6.517e-220 706.0
HFD3_k127_4165971_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 556.0
HFD3_k127_4165971_2 serine-type peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008587 389.0
HFD3_k127_4165971_3 PFAM 2Fe-2S -binding - - - 0.0000000000000000000000000000000000000000000000000000000000000006006 222.0
HFD3_k127_4165971_4 Tannase and feruloyl esterase - - - 0.000000000000000000000000000000000000000000000000001639 191.0
HFD3_k127_4165971_5 Ami_3 K01448 - 3.5.1.28 0.000005992 53.0
HFD3_k127_4186085_0 PQQ-like domain K05889 - 1.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009841 513.0
HFD3_k127_4186085_1 Carboxylesterase family K03929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 450.0
HFD3_k127_4186085_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007036 376.0
HFD3_k127_4186085_3 TIGRFAM phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 302.0
HFD3_k127_4186085_4 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000005069 217.0
HFD3_k127_4186085_5 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000005508 207.0
HFD3_k127_4186085_6 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000000001509 150.0
HFD3_k127_4186085_7 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.00000000000000001076 83.0
HFD3_k127_4187148_0 Sulfite reductase K00366,K00381,K00392 - 1.7.7.1,1.8.1.2,1.8.7.1 1.087e-287 908.0
HFD3_k127_4187148_1 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 415.0
HFD3_k127_4187148_10 Helix-hairpin-helix motif - - - 0.00000000000009989 81.0
HFD3_k127_4187148_2 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006393 408.0
HFD3_k127_4187148_3 Protein involved in outer membrane biogenesis K07289,K07290 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0032386,GO:0032879,GO:0032880,GO:0033157,GO:0044464,GO:0050789,GO:0051049,GO:0051223,GO:0060341,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:0090313,GO:1903533,GO:1903827,GO:1905475 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 372.0
HFD3_k127_4187148_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 355.0
HFD3_k127_4187148_5 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 351.0
HFD3_k127_4187148_6 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 - 2.3.1.29,2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002031 287.0
HFD3_k127_4187148_7 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000003944 195.0
HFD3_k127_4187148_8 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935,K02169 - 2.1.1.197,6.3.3.3 0.000000000000000000000000000000000000000000000000006264 188.0
HFD3_k127_4187148_9 - - - - 0.00000000000000000000002187 108.0
HFD3_k127_4189198_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 1.665e-261 839.0
HFD3_k127_4189198_1 outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000004853 232.0
HFD3_k127_4189198_2 Domain of unknown function (DUF1932) K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000004076 215.0
HFD3_k127_4189198_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000002931 178.0
HFD3_k127_4190535_0 NMT1-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 559.0
HFD3_k127_4190535_1 Alginate export - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 355.0
HFD3_k127_4190535_2 Binding-protein-dependent transport system inner membrane component K15577 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 344.0
HFD3_k127_4190535_3 ATPases associated with a variety of cellular activities K15578 - - 0.0000000004122 62.0
HFD3_k127_4200686_0 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005555 384.0
HFD3_k127_4200686_1 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000123 285.0
HFD3_k127_4200686_2 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002884 254.0
HFD3_k127_4200686_3 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000000000000004903 106.0
HFD3_k127_4200686_4 - - - - 0.00002155 57.0
HFD3_k127_4212395_0 radical SAM domain protein - - - 6.772e-241 759.0
HFD3_k127_4212395_1 COGs COG1680 Beta-lactamase class C and other penicillin binding protein - - - 4.711e-207 651.0
HFD3_k127_4212395_10 - - - - 0.00000000000000000000000000000000000000000000000009986 191.0
HFD3_k127_4212395_11 - - - - 0.0000000000000000000000000000002364 133.0
HFD3_k127_4212395_12 FAD linked K00803 - 2.5.1.26 0.000000000000000000000000000001957 124.0
HFD3_k127_4212395_13 - - - - 0.0000000000000008402 85.0
HFD3_k127_4212395_14 - - - - 0.000000000000001731 79.0
HFD3_k127_4212395_2 OPT oligopeptide transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004453 612.0
HFD3_k127_4212395_3 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 396.0
HFD3_k127_4212395_4 Trypsin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009058 359.0
HFD3_k127_4212395_5 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 343.0
HFD3_k127_4212395_6 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 335.0
HFD3_k127_4212395_7 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009421 282.0
HFD3_k127_4212395_8 PFAM peptidase K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000004004 264.0
HFD3_k127_4212395_9 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000146 215.0
HFD3_k127_4225011_0 Dehydrogenase K00030,K00052 - 1.1.1.41,1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005676 546.0
HFD3_k127_4225011_1 Sensor histidine kinase, HAMP domain-containing K07644 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007956 358.0
HFD3_k127_4225011_2 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009461 312.0
HFD3_k127_4225011_3 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000435 252.0
HFD3_k127_4225011_4 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000000002512 224.0
HFD3_k127_4225011_5 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000003085 194.0
HFD3_k127_4225011_6 Belongs to the ClpA ClpB family K03696 - - 0.00000000000000000000002669 110.0
HFD3_k127_4225011_7 metalloendopeptidase activity - - - 0.0000000005108 73.0
HFD3_k127_4333299_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 506.0
HFD3_k127_4333299_1 PFAM peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 325.0
HFD3_k127_4333299_10 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000002924 187.0
HFD3_k127_4333299_11 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000003167 176.0
HFD3_k127_4333299_12 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000004478 157.0
HFD3_k127_4333299_13 PFAM thiamine monophosphate synthase K00788 - 2.5.1.3 0.00000000000000000000000000000000000000004403 158.0
HFD3_k127_4333299_14 Phosphotriesterase family K07048 - - 0.000000000000000000000000000000000000003237 161.0
HFD3_k127_4333299_15 PFAM Glucose Sorbosone dehydrogenase K00117,K21430 GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016901,GO:0019842,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046872,GO:0048037,GO:0048038,GO:0055114,GO:0070968,GO:0097159,GO:1901363 1.1.5.2 0.000000000000000000000000000000005882 132.0
HFD3_k127_4333299_16 Belongs to the UPF0109 family K06960 - - 0.0000000000000000000000000000002329 124.0
HFD3_k127_4333299_17 - - - - 0.000000000000000000000000004188 111.0
HFD3_k127_4333299_18 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000000000001213 99.0
HFD3_k127_4333299_19 ribosome binding K02860 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 - 0.00000000000000000001526 98.0
HFD3_k127_4333299_2 YmdB-like protein K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 309.0
HFD3_k127_4333299_20 RNA polymerase-binding protein DksA K06204 - - 0.000000000000003585 81.0
HFD3_k127_4333299_22 - - - - 0.00000000005894 65.0
HFD3_k127_4333299_23 YtxH-like protein - - - 0.0000000008965 64.0
HFD3_k127_4333299_24 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000003279 61.0
HFD3_k127_4333299_25 - - - - 0.00000001381 57.0
HFD3_k127_4333299_26 - - - - 0.000001436 59.0
HFD3_k127_4333299_27 - - - - 0.000007896 51.0
HFD3_k127_4333299_3 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001136 286.0
HFD3_k127_4333299_4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000002958 259.0
HFD3_k127_4333299_5 Rubrerythrin K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000003817 259.0
HFD3_k127_4333299_6 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006725 268.0
HFD3_k127_4333299_7 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000001696 241.0
HFD3_k127_4333299_8 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000009734 229.0
HFD3_k127_4333299_9 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000002778 216.0
HFD3_k127_4377743_0 - - - - 5.673e-272 856.0
HFD3_k127_4377743_1 HAD superfamily, subfamily IIIB (Acid phosphatase) - - - 0.000000000000000000000000000000000000000000000000000001019 201.0
HFD3_k127_4377743_2 Ankyrin repeat-containing protein K21440 - - 0.000000000000000005315 93.0
HFD3_k127_4377743_3 TIGRFAM cytochrome c oxidase, cbb3-type, subunit III K00406 - - 0.00000002966 57.0
HFD3_k127_4434952_0 Trehalose utilisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005104 474.0
HFD3_k127_4434952_1 LVIVD repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 394.0
HFD3_k127_4450540_0 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004282 400.0
HFD3_k127_4450540_1 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000421 252.0
HFD3_k127_4450540_2 Transposase IS200 like K07491 - - 0.0000000000000000000000000000000000000000000000000795 186.0
HFD3_k127_4450540_3 - - - - 0.00000000000000000000000000000004345 134.0
HFD3_k127_4450540_4 VanZ like family - - - 0.000000000000000000000000000003703 124.0
HFD3_k127_4450540_5 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000001344 85.0
HFD3_k127_4513913_0 Cytochrome c - - - 1.839e-231 726.0
HFD3_k127_4513913_1 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 515.0
HFD3_k127_4513913_2 helix_turn_helix gluconate operon transcriptional repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 461.0
HFD3_k127_4513913_3 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 323.0
HFD3_k127_4513913_4 Family of unknown function (DUF1028) - - - 0.000000000000000000000000000000000000000000000009975 181.0
HFD3_k127_4513913_5 - - - - 0.00000000000000000000000000005161 120.0
HFD3_k127_4513913_7 MotA TolQ ExbB proton channel K03561,K03562 - - 0.0002377 46.0
HFD3_k127_4563282_0 transcription factor binding K02584,K12146,K12266,K15836,K21009 GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001150,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0042802,GO:0043170,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001141 - 4.77e-198 639.0
HFD3_k127_4563282_1 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000001412 205.0
HFD3_k127_4563282_2 HD domain - - - 0.0000000000000000000000000000000000000000000001529 188.0
HFD3_k127_4563282_3 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000002171 126.0
HFD3_k127_4586112_0 Carboxypeptidase regulatory-like domain - - - 0.0 1030.0
HFD3_k127_4586112_1 oxidoreductase activity - - - 1.819e-216 691.0
HFD3_k127_4586112_2 PFAM SMP-30 Gluconolaconase K08685,K14274 GO:0003674,GO:0003824,GO:0004341,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0005975,GO:0005996,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016051,GO:0016053,GO:0016787,GO:0016788,GO:0019752,GO:0019852,GO:0019853,GO:0042364,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046364,GO:0046394,GO:0046872,GO:0051186,GO:0051188,GO:0052689,GO:0071704,GO:1901576 1.4.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 448.0
HFD3_k127_4586112_3 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 338.0
HFD3_k127_4586112_4 Trehalose utilisation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009999 300.0
HFD3_k127_4586112_5 phosphorelay signal transduction system K02477,K07705,K21696 GO:0000156,GO:0000160,GO:0003674,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0023052,GO:0035556,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005805 281.0
HFD3_k127_4586112_6 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000001203 226.0
HFD3_k127_4586112_8 peroxiredoxin activity - - - 0.000000000000000000000000000009507 126.0
HFD3_k127_4586430_0 PQQ-like domain K00114 - 1.1.2.8 2.166e-217 691.0
HFD3_k127_4586430_1 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000001219 243.0
HFD3_k127_4586430_2 MacB-like periplasmic core domain K09808 - - 0.000000000000000000000000000000000000000000000000000000006587 214.0
HFD3_k127_4586430_3 - - - - 0.00000000000000000000000000000000000000004859 154.0
HFD3_k127_4586430_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000008014 110.0
HFD3_k127_4586430_5 Transcription factor zinc-finger K09981 - - 0.0000000000001911 74.0
HFD3_k127_4586430_6 protocatechuate 3,4-dioxygenase activity - - - 0.000002371 57.0
HFD3_k127_4596235_0 PFAM 4-hydroxyphenylacetate 3-hydroxylase K00483 - 1.14.14.9 4.651e-263 818.0
HFD3_k127_4596235_1 Amidohydrolase family - - - 1.106e-200 642.0
HFD3_k127_4596235_10 Sodium:dicarboxylate symporter family K11103 - - 0.00000000000000000000000000000000000000000000000000000000000000492 223.0
HFD3_k127_4596235_11 DinB family - - - 0.00000000000000000000000000000000000000000000000000000000000202 213.0
HFD3_k127_4596235_12 helix_turn_helix, arabinose operon control protein K07506 - - 0.000000000000000000000000000000000000000000000003914 184.0
HFD3_k127_4596235_13 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000002006 180.0
HFD3_k127_4596235_14 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000001224 175.0
HFD3_k127_4596235_15 Transcriptional regulator K13771 - - 0.0000000000000000000000000000000000000000001203 163.0
HFD3_k127_4596235_16 Bacterial-like globin K06886 - - 0.000000000000000000000000000000000000006588 153.0
HFD3_k127_4596235_18 Domain of unknown function (DUF4184) - - - 0.000000000000000000000000000000000001706 148.0
HFD3_k127_4596235_19 competence protein - - - 0.0000000000000000000000000000000946 132.0
HFD3_k127_4596235_2 MFS/sugar transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007735 494.0
HFD3_k127_4596235_20 Belongs to the ompA family - - - 0.00000000000000000000001033 114.0
HFD3_k127_4596235_21 membrane transporter protein K07090 - - 0.0000000000000000000002648 106.0
HFD3_k127_4596235_22 - - - - 0.0000000003288 66.0
HFD3_k127_4596235_24 Belongs to the amidase family K01426 - 3.5.1.4 0.000000002433 64.0
HFD3_k127_4596235_25 Bacterial regulatory proteins, tetR family - - - 0.00000002616 59.0
HFD3_k127_4596235_26 - - - - 0.00000003731 65.0
HFD3_k127_4596235_27 - - - - 0.00001273 57.0
HFD3_k127_4596235_3 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 429.0
HFD3_k127_4596235_4 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004369 408.0
HFD3_k127_4596235_5 TIGRFAM anion transporter K14445 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004631 349.0
HFD3_k127_4596235_6 Oxidoreductase molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001735 288.0
HFD3_k127_4596235_7 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008878,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0070566,GO:0071704,GO:1901576 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000005003 274.0
HFD3_k127_4596235_8 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001745 247.0
HFD3_k127_4596235_9 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000002476 239.0
HFD3_k127_4662933_0 Sugar (and other) transporter - - - 8.059e-213 673.0
HFD3_k127_4662933_1 lyase activity K11645 GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0042802,GO:0044424,GO:0044444,GO:0044464 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 552.0
HFD3_k127_4662933_10 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000004607 192.0
HFD3_k127_4662933_11 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000003518 101.0
HFD3_k127_4662933_12 Protein of unknown function (DUF2905) - - - 0.000000000000000005292 86.0
HFD3_k127_4662933_13 snoRNA binding - - - 0.0000001494 57.0
HFD3_k127_4662933_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005197 553.0
HFD3_k127_4662933_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 424.0
HFD3_k127_4662933_4 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002752 378.0
HFD3_k127_4662933_5 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway K08967 - 1.13.11.53,1.13.11.54 0.0000000000000000000000000000000000000000000000000000000000000000000000003383 250.0
HFD3_k127_4662933_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007197 261.0
HFD3_k127_4662933_7 tRNA processing K04075,K14058 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0016783,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000004201 226.0
HFD3_k127_4662933_8 Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene) K09880 - 3.1.3.77 0.00000000000000000000000000000000000000000000000000000000000194 215.0
HFD3_k127_4662933_9 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) K08964 - 4.2.1.109 0.00000000000000000000000000000000000000000000000000000001631 204.0
HFD3_k127_4664460_0 DNA ligase D, 3'-phosphoesterase domain K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 518.0
HFD3_k127_4664460_1 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000567 455.0
HFD3_k127_4664460_10 von Willebrand factor (vWF) type A domain - - - 0.000000000000000006731 94.0
HFD3_k127_4664460_14 Glycosyl transferase family 21 - - - 0.0004723 52.0
HFD3_k127_4664460_2 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 430.0
HFD3_k127_4664460_3 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K01147 GO:0000175,GO:0000178,GO:0000932,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019439,GO:0022613,GO:0032991,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0035770,GO:0036464,GO:0042254,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1902494,GO:1905354,GO:1990904 3.1.13.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005868 379.0
HFD3_k127_4664460_4 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 356.0
HFD3_k127_4664460_5 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 360.0
HFD3_k127_4664460_6 DNA ligase K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000005301 225.0
HFD3_k127_4664460_7 - - - - 0.00000000000000000000000000000000000000009175 169.0
HFD3_k127_4664460_8 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.0000000000000000000000000000000000005001 148.0
HFD3_k127_4664460_9 PFAM short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000004939 99.0
HFD3_k127_4683335_0 AcrB/AcrD/AcrF family - - - 2.065e-219 720.0
HFD3_k127_4683335_1 Peptidase, M16 K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000724 539.0
HFD3_k127_4683335_2 Peptidase, M16 K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 413.0
HFD3_k127_4683335_3 cytochrome C peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000018 291.0
HFD3_k127_4683335_4 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000002907 164.0
HFD3_k127_4683335_5 PFAM Carbohydrate-selective porin OprB - - - 0.0000000000000000000000000000002223 141.0
HFD3_k127_4683335_6 40-residue YVTN family beta-propeller repeat - - - 0.000000000000000000000007836 115.0
HFD3_k127_4683335_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.000000000000007001 84.0
HFD3_k127_4683949_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018995,GO:0019058,GO:0019068,GO:0020003,GO:0022610,GO:0023051,GO:0023056,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044174,GO:0044175,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279,GO:0044403,GO:0044406,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044650,GO:0044764,GO:0046812,GO:0046872,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0065007,GO:0065010,GO:0097159,GO:0097367,GO:0101031,GO:1901222,GO:1901224,GO:1901265,GO:1901363,GO:1902531,GO:1902533,GO:1990220,GO:2000535 - 2.76e-256 799.0
HFD3_k127_4683949_1 Heat shock 70 kDa protein K04043 - - 3.634e-251 782.0
HFD3_k127_4683949_10 Amidohydrolase K22213 - 4.1.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005742 319.0
HFD3_k127_4683949_11 PA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004686 310.0
HFD3_k127_4683949_12 DinB family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 294.0
HFD3_k127_4683949_13 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008582 267.0
HFD3_k127_4683949_14 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001232 270.0
HFD3_k127_4683949_15 Phosphatidylethanolamine-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001869 260.0
HFD3_k127_4683949_16 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005242 254.0
HFD3_k127_4683949_17 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001582 251.0
HFD3_k127_4683949_18 Ankyrin repeat - - - 0.000000000000000000000000000000000000000000000000000000000003279 226.0
HFD3_k127_4683949_19 IstB-like ATP binding protein K02315,K04076 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000002145 215.0
HFD3_k127_4683949_2 DNA topological change K03168 - 5.99.1.2 5.564e-196 642.0
HFD3_k127_4683949_20 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000006392 214.0
HFD3_k127_4683949_21 Methyltransferase domain K22309 - 2.1.1.344 0.0000000000000000000000000000000000000000000000000006326 190.0
HFD3_k127_4683949_22 - - - - 0.000000000000000000000000000000000000000000000000003358 198.0
HFD3_k127_4683949_23 - - - - 0.0000000000000000000000000000000000000000000002583 177.0
HFD3_k127_4683949_24 - - - - 0.00000000000000000000000000000000000000000001273 167.0
HFD3_k127_4683949_25 MerR HTH family regulatory protein K13640 - - 0.0000000000000000000000000000000000000001512 153.0
HFD3_k127_4683949_26 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 - 0.0000000000000000000000000000000000000007192 150.0
HFD3_k127_4683949_27 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000001064 149.0
HFD3_k127_4683949_28 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000003512 146.0
HFD3_k127_4683949_29 - - - - 0.000000000000000000000000000006293 129.0
HFD3_k127_4683949_3 FMN binding K00104,K16422 - 1.1.3.15,1.1.3.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 415.0
HFD3_k127_4683949_30 - - - - 0.000000000000000000000000006027 116.0
HFD3_k127_4683949_31 NIPSNAP - - - 0.0000000000000000009243 95.0
HFD3_k127_4683949_32 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000263 64.0
HFD3_k127_4683949_33 - - - - 0.0000001608 57.0
HFD3_k127_4683949_34 DinB superfamily - - - 0.00009516 52.0
HFD3_k127_4683949_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 407.0
HFD3_k127_4683949_5 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 406.0
HFD3_k127_4683949_6 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 401.0
HFD3_k127_4683949_7 FecR protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 417.0
HFD3_k127_4683949_8 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 344.0
HFD3_k127_4683949_9 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 344.0
HFD3_k127_4687447_0 Carboxypeptidase regulatory-like domain - - - 0.0 1158.0
HFD3_k127_4687447_1 SMART Elongator protein 3 MiaB NifB - - - 3.473e-205 651.0
HFD3_k127_4687447_2 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 606.0
HFD3_k127_4687447_3 PFAM Carboxylesterase K03929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004103 422.0
HFD3_k127_4687447_4 protein-glutamate O-methyltransferase activity K00575,K03408,K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 319.0
HFD3_k127_4687447_5 Putative 2OG-Fe(II) oxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001289 263.0
HFD3_k127_4696722_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2119.0
HFD3_k127_4696722_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046,K13797 GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.0 1791.0
HFD3_k127_4696722_2 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 319.0
HFD3_k127_4696722_3 Participates in transcription elongation, termination and antitermination K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001926 263.0
HFD3_k127_4696722_4 Ribosomal protein L11/L12 K02867 - - 0.000000000000000000000000000000000000000000000000000000000000001141 222.0
HFD3_k127_4696722_5 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000000000000000005363 185.0
HFD3_k127_4696722_6 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000000000000000000000000000000004268 172.0
HFD3_k127_4696722_7 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000000004708 166.0
HFD3_k127_4696722_8 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000287 76.0
HFD3_k127_4696722_9 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000000000000003766 78.0
HFD3_k127_4708641_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 464.0
HFD3_k127_4708641_1 Cro/C1-type HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000005758 220.0
HFD3_k127_471330_0 iron dependent repressor - - - 2.892e-194 620.0
HFD3_k127_471330_1 HD domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000262 205.0
HFD3_k127_4729618_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1032.0
HFD3_k127_4729618_1 B12 binding domain - - - 1.071e-231 734.0
HFD3_k127_4729618_10 Belongs to the MlaE permease family K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003661 284.0
HFD3_k127_4729618_11 COG3911 Predicted ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002182 274.0
HFD3_k127_4729618_12 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003854 272.0
HFD3_k127_4729618_13 Belongs to the NadC ModD family K00767 GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003891 274.0
HFD3_k127_4729618_14 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000006086 256.0
HFD3_k127_4729618_15 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004311 249.0
HFD3_k127_4729618_16 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009973 250.0
HFD3_k127_4729618_17 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000006016 240.0
HFD3_k127_4729618_18 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000008575 232.0
HFD3_k127_4729618_19 FMN binding - - - 0.0000000000000000000000000000000000000000000000000000000000004988 224.0
HFD3_k127_4729618_2 B12 binding domain - - - 5.881e-210 662.0
HFD3_k127_4729618_20 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000004974 212.0
HFD3_k127_4729618_21 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000004288 190.0
HFD3_k127_4729618_22 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000009414 187.0
HFD3_k127_4729618_23 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000002835 181.0
HFD3_k127_4729618_24 TIGRFAM Outer membrane assembly lipoprotein YfiO K05807 - - 0.000000000000000000000000000000000000000000000001829 187.0
HFD3_k127_4729618_25 Belongs to the P(II) protein family K04751,K04752 - - 0.00000000000000000000000000000000000002582 147.0
HFD3_k127_4729618_26 long-chain fatty acid transport protein - - - 0.0000000000000000000000000000000000004052 164.0
HFD3_k127_4729618_27 Amidohydrolase family - - - 0.00000000000000000000000000000000007371 143.0
HFD3_k127_4729618_28 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000002519 136.0
HFD3_k127_4729618_29 cheY-homologous receiver domain - - - 0.000000000000000000000000000001539 132.0
HFD3_k127_4729618_3 PFAM multicopper oxidase type 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002818 572.0
HFD3_k127_4729618_30 PASTA domain K12132 - 2.7.11.1 0.00000000000000000000000000000217 129.0
HFD3_k127_4729618_31 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.00000000000000000000000000004458 128.0
HFD3_k127_4729618_32 PFAM SNARE associated Golgi protein - - - 0.000000000000000000001502 109.0
HFD3_k127_4729618_33 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.00000000000000000000183 97.0
HFD3_k127_4729618_34 E1-E2 ATPase K17686 - 3.6.3.54 0.0000000000000000000456 93.0
HFD3_k127_4729618_35 - - - - 0.00000000000002049 83.0
HFD3_k127_4729618_36 Short C-terminal domain K08982 - - 0.000000000006079 70.0
HFD3_k127_4729618_37 PFAM heat shock protein DnaJ domain protein K03686,K05516 - - 0.000000003518 65.0
HFD3_k127_4729618_38 - - - - 0.00000001408 61.0
HFD3_k127_4729618_39 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000001311 61.0
HFD3_k127_4729618_4 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003575 489.0
HFD3_k127_4729618_40 Serine kinase - - - 0.0002635 53.0
HFD3_k127_4729618_5 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 467.0
HFD3_k127_4729618_6 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 452.0
HFD3_k127_4729618_7 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006509 440.0
HFD3_k127_4729618_8 oxidoreductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 389.0
HFD3_k127_4729618_9 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 291.0
HFD3_k127_4729772_0 PFAM Peptidase M16 K07263 - - 0.0 1024.0
HFD3_k127_4729772_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 3.705e-244 774.0
HFD3_k127_4729772_10 Tfp pilus assembly protein FimV - - - 0.0000000000000000002489 101.0
HFD3_k127_4729772_11 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000009873 80.0
HFD3_k127_4729772_12 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000002466 66.0
HFD3_k127_4729772_13 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.00004497 54.0
HFD3_k127_4729772_2 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 4.546e-237 757.0
HFD3_k127_4729772_3 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 565.0
HFD3_k127_4729772_4 alcohol dehydrogenase K13979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 485.0
HFD3_k127_4729772_5 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004561 482.0
HFD3_k127_4729772_6 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 404.0
HFD3_k127_4729772_7 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000001654 248.0
HFD3_k127_4729772_8 ABC 3 transport family K02075,K09816 - - 0.00000000000000000000000000000000000000000000000000000000000000000002292 250.0
HFD3_k127_4729772_9 Belongs to the bacterial solute-binding protein 9 family K02077,K09815,K09818 - - 0.00000000000000000000000000000000000000000000000000000000000000005702 235.0
HFD3_k127_4737917_0 xanthine dehydrogenase activity - - - 0.0 1187.0
HFD3_k127_4737917_1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 1.203e-297 923.0
HFD3_k127_4737917_10 - - - - 0.00000000000000000000000000000000002477 147.0
HFD3_k127_4737917_11 Evidence 5 No homology to any previously reported sequences K07156,K07245,K14166 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000002794 61.0
HFD3_k127_4737917_12 - - - - 0.0000005698 59.0
HFD3_k127_4737917_2 PQQ-like domain K00114 - 1.1.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005065 536.0
HFD3_k127_4737917_3 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 460.0
HFD3_k127_4737917_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 336.0
HFD3_k127_4737917_5 Domain of unknown function (DUF4010) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 327.0
HFD3_k127_4737917_6 2Fe-2S -binding domain protein K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002292 270.0
HFD3_k127_4737917_7 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000002272 162.0
HFD3_k127_4737917_8 - - - - 0.000000000000000000000000000000000000002422 152.0
HFD3_k127_4737917_9 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000004548 155.0
HFD3_k127_4748153_0 Formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.0 1500.0
HFD3_k127_4748153_1 AcrB/AcrD/AcrF family K03296 - - 0.0 1296.0
HFD3_k127_4748153_10 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008862 413.0
HFD3_k127_4748153_11 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 403.0
HFD3_k127_4748153_12 peptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008257 397.0
HFD3_k127_4748153_13 Glucose / Sorbosone dehydrogenase K21430 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009878 394.0
HFD3_k127_4748153_14 peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 381.0
HFD3_k127_4748153_15 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 385.0
HFD3_k127_4748153_16 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007285 349.0
HFD3_k127_4748153_17 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 346.0
HFD3_k127_4748153_18 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 303.0
HFD3_k127_4748153_19 Protein of unknown function (DUF1211) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006709 284.0
HFD3_k127_4748153_2 MacB-like periplasmic core domain - - - 6.518e-263 839.0
HFD3_k127_4748153_20 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002125 289.0
HFD3_k127_4748153_21 Belongs to the glutamate synthase family K22083 - 2.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000005484 248.0
HFD3_k127_4748153_22 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000009689 233.0
HFD3_k127_4748153_23 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000002274 232.0
HFD3_k127_4748153_24 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000001022 211.0
HFD3_k127_4748153_25 Thioredoxin-like [2Fe-2S] ferredoxin K00127 - - 0.00000000000000000000000000000000000000000000000000000000003612 208.0
HFD3_k127_4748153_26 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000005512 217.0
HFD3_k127_4748153_27 transcriptional regulator PadR family - - - 0.00000000000000000000000000000000000000000000004042 171.0
HFD3_k127_4748153_28 Bacterial regulatory proteins, tetR family K09017 - - 0.000000000000000000000000000000000005773 145.0
HFD3_k127_4748153_29 amidohydrolase - - - 0.000000000000000000000000003104 126.0
HFD3_k127_4748153_3 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00124 - - 1.331e-252 789.0
HFD3_k127_4748153_30 - - - - 0.00000000000000000000000002912 121.0
HFD3_k127_4748153_31 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000007008 110.0
HFD3_k127_4748153_32 - - - - 0.00000000000000000000001017 113.0
HFD3_k127_4748153_33 Peptidase family S41 - - - 0.00000000000000000000001289 105.0
HFD3_k127_4748153_34 - - - - 0.000000000000000000002239 97.0
HFD3_k127_4748153_35 - - - - 0.00000000000000000000955 96.0
HFD3_k127_4748153_36 formate dehydrogenase delta subunit K00126 - 1.17.1.9 0.000000000000000002093 86.0
HFD3_k127_4748153_37 - - - - 0.00000000000000008819 89.0
HFD3_k127_4748153_38 YCII-related domain - - - 0.000000000000009825 78.0
HFD3_k127_4748153_39 Peptidase family S41 K03797 - 3.4.21.102 0.0000004227 59.0
HFD3_k127_4748153_4 CAAX protease self-immunity K07052 - - 1.62e-204 677.0
HFD3_k127_4748153_40 - - - - 0.00001111 55.0
HFD3_k127_4748153_5 PFAM 4Fe-4S binding domain - - - 9.594e-202 638.0
HFD3_k127_4748153_6 MacB-like periplasmic core domain - - - 2.379e-199 647.0
HFD3_k127_4748153_7 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003759 556.0
HFD3_k127_4748153_8 PhoD-like phosphatase, N-terminal domain K01113 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000358 519.0
HFD3_k127_4748153_9 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006688 497.0
HFD3_k127_4784715_0 Carboxypeptidase regulatory-like domain - - - 2.986e-218 723.0
HFD3_k127_4784715_1 Ankyrin repeat - - - 0.0000000000000000000008014 110.0
HFD3_k127_4795514_0 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002129 282.0
HFD3_k127_4795514_1 ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component - - - 0.00000000000000000000000000000000000000000000000009022 183.0
HFD3_k127_4795514_2 Winged helix DNA-binding domain - - - 0.00000000000000000000000000000000000226 141.0
HFD3_k127_4795917_0 Protein of unknown function (DUF4197) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007932 258.0
HFD3_k127_4795917_1 - - - - 0.0000000000000000000000000000000000694 145.0
HFD3_k127_4795917_2 - - - - 0.000000000000000000000000004002 115.0
HFD3_k127_481137_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 4.273e-218 696.0
HFD3_k127_481137_1 NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 558.0
HFD3_k127_481137_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 464.0
HFD3_k127_4811619_0 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002901 440.0
HFD3_k127_4811619_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004084 325.0
HFD3_k127_4811619_2 Glycosyltransferase like family 2 - - - 0.00000001313 57.0
HFD3_k127_481385_0 response regulator - - - 2.514e-196 621.0
HFD3_k127_481385_1 O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000698 511.0
HFD3_k127_481385_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002971 282.0
HFD3_k127_481385_11 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000001591 172.0
HFD3_k127_481385_12 permease - - - 0.0000000000000000000000000000000000000000000509 175.0
HFD3_k127_481385_13 COGs COG1670 Acetyltransferase including N-acetylase of ribosomal protein - - - 0.0000000000000000000000000000000000000001807 160.0
HFD3_k127_481385_14 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000134 153.0
HFD3_k127_481385_15 Lytic transglycosylase catalytic K08309 - - 0.00000000000000000000000000000001459 146.0
HFD3_k127_481385_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 464.0
HFD3_k127_481385_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007374 395.0
HFD3_k127_481385_4 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000977 389.0
HFD3_k127_481385_5 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 380.0
HFD3_k127_481385_6 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004672 348.0
HFD3_k127_481385_7 AhpC/TSA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004932 335.0
HFD3_k127_481385_8 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007098 322.0
HFD3_k127_481385_9 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006517 315.0
HFD3_k127_4835248_0 Belongs to the argininosuccinate synthase family. Type 2 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 1.415e-246 767.0
HFD3_k127_4835248_1 Dehydrogenase K00114 - 1.1.2.8 3.364e-211 672.0
HFD3_k127_4835248_10 Bacterial membrane protein YfhO - - - 0.00000002252 66.0
HFD3_k127_4835248_2 MviN-like protein K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 608.0
HFD3_k127_4835248_3 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 409.0
HFD3_k127_4835248_4 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 350.0
HFD3_k127_4835248_5 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 327.0
HFD3_k127_4835248_6 BlaR1 peptidase M56 - - - 0.00000000000000000000000000000000000000000003158 179.0
HFD3_k127_4835248_7 Penicillinase repressor - - - 0.000000000000000000000000000000004112 132.0
HFD3_k127_4835248_8 Peptidase family M48 - - - 0.0000000000000000000000000000001394 139.0
HFD3_k127_4835248_9 ABC transporter substrate binding protein K01989 - - 0.0000000000000000003856 99.0
HFD3_k127_4849429_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 308.0
HFD3_k127_4849429_1 Putative restriction endonuclease - - - 0.000000000000000000000000000000000000000000000001165 180.0
HFD3_k127_4849429_2 Thioredoxin-like - - - 0.00000000000000000000000003465 123.0
HFD3_k127_4863517_0 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007858 347.0
HFD3_k127_4863517_1 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000005158 227.0
HFD3_k127_4863517_2 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000000000000000000000000001172 177.0
HFD3_k127_4913413_0 Dehydrogenase K00117 - 1.1.5.2 1.083e-208 668.0
HFD3_k127_4913413_1 PFAM alpha beta hydrolase fold K01561 - 3.8.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006516 302.0
HFD3_k127_4913413_2 Glycosyl hydrolase family 10 K01181 - 3.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000001875 231.0
HFD3_k127_4919043_0 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 283.0
HFD3_k127_4919043_1 metal-dependent phosphohydrolase, HD sub domain K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001508 296.0
HFD3_k127_4919043_2 - - - - 0.00000000000000000000000000000000000000000000001267 180.0
HFD3_k127_4919043_4 phosphohistidine phosphatase, SixA K08296 - - 0.00000000000000000002157 98.0
HFD3_k127_4919043_5 Putative porin - - - 0.00000004305 66.0
HFD3_k127_4928524_0 PQQ-like domain K00114 - 1.1.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 374.0
HFD3_k127_4928524_1 DinB family - - - 0.000000000000000000000000000000000000004165 152.0
HFD3_k127_4928524_2 metal-dependent hydrolase of the TIM-barrel fold K07045 - - 0.0000000001863 61.0
HFD3_k127_4943064_0 4-alpha-glucanotransferase K00705 - 2.4.1.25 2.104e-286 897.0
HFD3_k127_4943064_1 stress-induced mitochondrial fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 424.0
HFD3_k127_4943064_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003571 372.0
HFD3_k127_4943064_3 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 319.0
HFD3_k127_4960346_0 Carboxypeptidase regulatory-like domain - - - 1.621e-208 696.0
HFD3_k127_4960346_1 Belongs to the PdaD family K02626 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000005441 264.0
HFD3_k127_4960346_2 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000001561 230.0
HFD3_k127_4960346_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000003581 109.0
HFD3_k127_4975345_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 6.499e-283 877.0
HFD3_k127_4975345_1 nitrite transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009834 375.0
HFD3_k127_4975345_2 nitrite reductase [NAD(P)H] activity K00363,K05710 - 1.7.1.15 0.000000000000000000000000196 110.0
HFD3_k127_4987039_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 2.063e-256 804.0
HFD3_k127_4987039_1 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 482.0
HFD3_k127_4987039_2 NADPH:quinone reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003391 368.0
HFD3_k127_4987039_3 PFAM major facilitator superfamily MFS_1 K08177 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008304 334.0
HFD3_k127_4987039_4 acyl-CoA transferases carnitine dehydratase K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 301.0
HFD3_k127_4989248_0 Carboxypeptidase regulatory-like domain - - - 4.633e-310 989.0
HFD3_k127_4989248_1 Malate synthase K01638 - 2.3.3.9 7.742e-302 935.0
HFD3_k127_4989248_10 ioli protein K06606 - 5.3.99.11 0.0000000000000000000000007721 115.0
HFD3_k127_4989248_11 Carboxypeptidase regulatory-like domain - - - 0.0000768 55.0
HFD3_k127_4989248_2 phosphopyruvate hydratase activity K01689 GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 581.0
HFD3_k127_4989248_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003041 563.0
HFD3_k127_4989248_4 Deoxyhypusine synthase K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 484.0
HFD3_k127_4989248_5 Cys/Met metabolism PLP-dependent enzyme K10907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 408.0
HFD3_k127_4989248_6 PFAM Glucose Sorbosone dehydrogenase K21430 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 316.0
HFD3_k127_4989248_7 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000004686 242.0
HFD3_k127_4989248_8 Putative cyclase K07130 - 3.5.1.9 0.000000000000000000000000000000000000000000000000000000885 205.0
HFD3_k127_4989248_9 Aminoacyl-tRNA editing domain K19055 - - 0.000000000000000000000000000000000000002504 153.0
HFD3_k127_5000051_0 DNA topological change K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 495.0
HFD3_k127_5000051_1 Protein of unknown function (DUF1552) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004053 475.0
HFD3_k127_5011836_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 4.877e-287 891.0
HFD3_k127_5011836_1 Penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 2.543e-226 723.0
HFD3_k127_5011836_10 Hydrolase, TatD family K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000576 268.0
HFD3_k127_5011836_11 pfam abc K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001526 263.0
HFD3_k127_5011836_12 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000001533 234.0
HFD3_k127_5011836_13 PFAM Haloacid dehalogenase domain protein hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000006225 213.0
HFD3_k127_5011836_14 PFAM ROK family protein K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000954 216.0
HFD3_k127_5011836_15 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000002592 179.0
HFD3_k127_5011836_16 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.000000000000000000000000000000003131 133.0
HFD3_k127_5011836_17 BadF BadG BcrA BcrD - - - 0.000000000000000000000000000003033 131.0
HFD3_k127_5011836_18 Rhodanese Homology Domain - - - 0.000000000000000000000003576 106.0
HFD3_k127_5011836_19 Protein of unknown function with PCYCGC motif - - - 0.000000000000004764 81.0
HFD3_k127_5011836_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 5.458e-205 657.0
HFD3_k127_5011836_3 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 616.0
HFD3_k127_5011836_4 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029,K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005482 489.0
HFD3_k127_5011836_5 PFAM Glycosyl transferase, family K00756 - 2.4.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005299 428.0
HFD3_k127_5011836_6 Protein of unknown function DUF111 K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 363.0
HFD3_k127_5011836_7 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 304.0
HFD3_k127_5011836_8 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 306.0
HFD3_k127_5011836_9 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009454 274.0
HFD3_k127_5013504_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 8.245e-211 687.0
HFD3_k127_5013504_1 response to abiotic stimulus K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000001197 227.0
HFD3_k127_5013504_3 mRNA binding K07339 - - 0.0002876 48.0
HFD3_k127_5013504_4 DNA integration - - - 0.000392 44.0
HFD3_k127_5039311_0 GTP-binding protein TypA K06207 - - 3.283e-314 970.0
HFD3_k127_5039311_1 Ammonium Transporter Family K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 548.0
HFD3_k127_5039311_2 HI0933 family K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004481 432.0
HFD3_k127_5039311_3 Mitochondrial biogenesis AIM24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 436.0
HFD3_k127_5039311_4 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000006225 137.0
HFD3_k127_5095427_0 Glycosyltransferase, group 2 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 463.0
HFD3_k127_5095427_1 SpoIID LytB domain protein K06381 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 402.0
HFD3_k127_5095427_10 RNA-binding - - - 0.0002089 49.0
HFD3_k127_5095427_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004053 331.0
HFD3_k127_5095427_3 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002676 253.0
HFD3_k127_5095427_4 SpoIID LytB domain protein K06381 - - 0.0000000000000000000000000000000000000000000000000000000003629 216.0
HFD3_k127_5095427_5 PFAM fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000003195 163.0
HFD3_k127_5095427_6 Protein of unknown function (DUF1460) - - - 0.00000000000000000000000004938 115.0
HFD3_k127_5095427_7 AhpC Tsa family - - - 0.0000000000000006411 85.0
HFD3_k127_5095427_8 Protein of unknown function, DUF255 K06888 - - 0.0000001382 55.0
HFD3_k127_5095427_9 metal ion permease K07089 - - 0.0000003738 56.0
HFD3_k127_5099552_0 - - - - 0.0000000000000000000000000000009558 130.0
HFD3_k127_5099552_1 - - - - 0.0000000000000000000000000000493 121.0
HFD3_k127_5168693_0 succinyl-diaminopimelate desuccinylase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 531.0
HFD3_k127_5168693_1 Involved in the heme and chlorophyll biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0003824,GO:0004109,GO:0005488,GO:0005515,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016634,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0042803,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0046501,GO:0046983,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 395.0
HFD3_k127_5168693_2 Bifunctional nuclease K08999 - - 0.00000000000000000000000000000000000000000000000000000000000000000001912 235.0
HFD3_k127_5168693_3 HsdM N-terminal domain K03427 - 2.1.1.72 0.0000000000000000000000000007615 117.0
HFD3_k127_5192389_0 Phosphofructokinase - - - 8.173e-200 632.0
HFD3_k127_5192389_1 Multicopper oxidase K06324 - 1.16.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 436.0
HFD3_k127_5192389_2 PFAM OsmC family protein K04063 - - 0.0000000000000000000000000000000000000000000000000008263 186.0
HFD3_k127_519781_0 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 384.0
HFD3_k127_519781_1 PAP2 superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 365.0
HFD3_k127_519781_2 - - - - 0.00000000000000000000000000001032 124.0
HFD3_k127_519781_3 phospholipase Carboxylesterase - - - 0.000000000000000000000000005368 121.0
HFD3_k127_520392_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006814 385.0
HFD3_k127_520392_1 Domain of unknown function (DUF1732) - - - 0.000000000000000000000000000000000000000000000000000003752 203.0
HFD3_k127_520392_2 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000003902 196.0
HFD3_k127_520392_3 DNA-directed 5'-3' RNA polymerase activity K03060 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.00000002972 57.0
HFD3_k127_5228963_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 499.0
HFD3_k127_5228963_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 444.0
HFD3_k127_5228963_2 Mur ligase family, catalytic domain K02558 - 6.3.2.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009859 443.0
HFD3_k127_5228963_3 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 432.0
HFD3_k127_5228963_4 D-isomer specific 2-hydroxyacid dehydrogenase catalytic region K00015 - 1.1.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 344.0
HFD3_k127_5228963_5 LD-carboxypeptidase K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000000000000000000000003046 259.0
HFD3_k127_5228963_6 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000002225 251.0
HFD3_k127_5228963_7 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000152 173.0
HFD3_k127_5228963_8 Bacterial membrane protein, YfhO - - - 0.00000000000000000000000000000000000000000002628 185.0
HFD3_k127_5237274_0 Belongs to the RtcB family K14415 - 6.5.1.3 2.564e-224 703.0
HFD3_k127_5237274_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006535 387.0
HFD3_k127_5237274_2 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007153 344.0
HFD3_k127_5237274_3 phosphoribosyltransferase K07100 - - 0.000000000000000000000000000000000000000000000000000000000000000000001312 241.0
HFD3_k127_5237274_4 'Cold-shock' DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000002773 204.0
HFD3_k127_5237274_5 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000001548 183.0
HFD3_k127_5237274_6 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000302 183.0
HFD3_k127_5237274_7 Transcription termination factor nusG - - - 0.0000000000000000000000000000000000001455 149.0
HFD3_k127_5237274_8 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000003414 120.0
HFD3_k127_5308643_0 cytochrome K17230 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004634 415.0
HFD3_k127_5308643_1 PQQ-like domain K00114,K20937 - 1.1.2.8,1.1.5.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 377.0
HFD3_k127_5308643_2 Bacterial PH domain K08981 - - 0.000000000000000000000000000001312 128.0
HFD3_k127_5337670_0 DNA topological change K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008349 586.0
HFD3_k127_5337670_1 Protein of unknown function (DUF1552) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009036 425.0
HFD3_k127_5353252_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 1.027e-290 917.0
HFD3_k127_5353252_1 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006656 592.0
HFD3_k127_5353252_10 Protein of unknown function (DUF3500) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 324.0
HFD3_k127_5353252_11 Secretin and TonB N terminus short domain K02666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002879 293.0
HFD3_k127_5353252_12 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001328 271.0
HFD3_k127_5353252_13 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH K22136 - - 0.000000000000000000000000000000000000000000000000000000000000000004766 246.0
HFD3_k127_5353252_14 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000004801 225.0
HFD3_k127_5353252_15 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000004314 195.0
HFD3_k127_5353252_16 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000905 164.0
HFD3_k127_5353252_17 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000006974 149.0
HFD3_k127_5353252_18 Acetyl-CoA carboxylase, biotin carboxyl carrier protein K01571,K01960 - 4.1.1.3,6.4.1.1 0.0000000000000000000000000000000005653 137.0
HFD3_k127_5353252_19 Histidine kinase-like ATPase domain K01338,K04757,K06379,K08282,K17752 - 2.7.11.1,3.4.21.53 0.000000000000000000000000000000001497 133.0
HFD3_k127_5353252_2 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005994 533.0
HFD3_k127_5353252_20 Lipopolysaccharide-assembly - - - 0.0000000000000000001997 94.0
HFD3_k127_5353252_21 - - - - 0.0000000000000000008393 98.0
HFD3_k127_5353252_22 Helix-turn-helix domain - - - 0.000000000000000005032 87.0
HFD3_k127_5353252_23 PFAM Fimbrial assembly family protein K02663 - - 0.00000000000006713 79.0
HFD3_k127_5353252_24 - - - - 0.00000000004721 76.0
HFD3_k127_5353252_25 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.000000001765 69.0
HFD3_k127_5353252_26 RecX family K03565 - - 0.00000001421 61.0
HFD3_k127_5353252_27 PFAM Pilus assembly protein PilO K02664 - - 0.00000005106 63.0
HFD3_k127_5353252_28 Roadblock/LC7 domain - - - 0.000001334 57.0
HFD3_k127_5353252_29 - - - - 0.00002311 52.0
HFD3_k127_5353252_3 PFAM Prenyltransferase squalene oxidase K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 506.0
HFD3_k127_5353252_4 glycosyl transferase group 1 K00754 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004056 467.0
HFD3_k127_5353252_5 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 459.0
HFD3_k127_5353252_6 C-terminal, D2-small domain, of ClpB protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002554 452.0
HFD3_k127_5353252_7 copper resistance - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 398.0
HFD3_k127_5353252_8 Type IV pilus assembly protein PilM; K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007079 353.0
HFD3_k127_5353252_9 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007675 364.0
HFD3_k127_5362750_0 AAA ATPase K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 571.0
HFD3_k127_5362750_1 extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 458.0
HFD3_k127_5362750_2 Amidohydrolase K10220 - 4.2.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005513 414.0
HFD3_k127_5362750_3 beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001832 283.0
HFD3_k127_5362750_4 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.00000000000000000000000000000000000000000000003749 179.0
HFD3_k127_5362750_5 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.7.7.87 0.00000000000000000000000000000000000000000003764 168.0
HFD3_k127_5362750_6 DUF218 domain - - - 0.0000000000000000000000000000000000007057 147.0
HFD3_k127_5362750_7 - - - - 0.00000000000000000000018 104.0
HFD3_k127_5395320_0 DNA-directed DNA polymerase K02337 - 2.7.7.7 0.0 1264.0
HFD3_k127_5395320_1 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003613 603.0
HFD3_k127_5395320_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 356.0
HFD3_k127_5395320_3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0001209 45.0
HFD3_k127_5395860_0 Ser Thr phosphatase family protein K03547 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 321.0
HFD3_k127_5395860_1 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000000000000000000000001169 239.0
HFD3_k127_5447230_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1618.0
HFD3_k127_5447230_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002888 497.0
HFD3_k127_5447230_2 nucleotidyltransferase activity K01154,K07076 - 3.1.21.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 398.0
HFD3_k127_5447230_3 Transcriptional Regulator, AraC family - - - 0.00000000000000000000000000000000000000000000007093 183.0
HFD3_k127_5447230_4 SnoaL-like domain - - - 0.0000000000000000000000000000000000000001669 156.0
HFD3_k127_5447230_5 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000004716 93.0
HFD3_k127_5448612_0 Carboxypeptidase regulatory-like domain - - - 3.49e-319 1004.0
HFD3_k127_5448612_1 oxidoreductase activity - - - 6.316e-239 759.0
HFD3_k127_5448612_10 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000003273 139.0
HFD3_k127_5448612_11 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000003163 110.0
HFD3_k127_5448612_12 Belongs to the frataxin family K06202,K19054 GO:0003674,GO:0003824,GO:0004322,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006790,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0008199,GO:0009987,GO:0016043,GO:0016226,GO:0016491,GO:0016530,GO:0016722,GO:0016724,GO:0018282,GO:0018283,GO:0019538,GO:0019725,GO:0022607,GO:0030003,GO:0031163,GO:0033554,GO:0034599,GO:0034986,GO:0036211,GO:0042221,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0050896,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071704,GO:0071840,GO:0098771,GO:0140104,GO:1901564 1.16.3.1 0.000000000000000000004165 97.0
HFD3_k127_5448612_13 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000000002422 86.0
HFD3_k127_5448612_14 - - - - 0.000000001451 66.0
HFD3_k127_5448612_15 - - - - 0.00009255 51.0
HFD3_k127_5448612_2 PQQ-like domain K00117 - 1.1.5.2 3.8e-204 657.0
HFD3_k127_5448612_3 Protein involved in outer membrane biogenesis - - - 1.661e-201 640.0
HFD3_k127_5448612_4 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 442.0
HFD3_k127_5448612_5 MFS transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 438.0
HFD3_k127_5448612_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002714 319.0
HFD3_k127_5448612_7 Protein of unknown function (DUF3738) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 327.0
HFD3_k127_5448612_8 Belongs to the Dps family K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000005721 214.0
HFD3_k127_5448612_9 - - - - 0.0000000000000000000000000000000002766 137.0
HFD3_k127_5453940_0 PFAM FAD linked oxidase domain protein - - - 8.547e-311 978.0
HFD3_k127_5453940_1 FAD binding domain K00481 - 1.14.13.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 493.0
HFD3_k127_5453940_10 Transcriptional regulator K02584 - - 0.000000000000000000000000000000000000000000000000000000000000001498 251.0
HFD3_k127_5453940_11 TIGRFAM RNA polymerase sigma factor, FliA WhiG family K02405 - - 0.00000000000000000000000000000000000000000000000000000000002608 211.0
HFD3_k127_5453940_12 - - - - 0.000000000000000000000000000000000000000000000000000000001068 215.0
HFD3_k127_5453940_13 Bacteriocin-protection, YdeI or OmpD-Associated K06878 - - 0.0000000000000000000000000000000000000000000001092 176.0
HFD3_k127_5453940_14 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000002388 177.0
HFD3_k127_5453940_15 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000001423 148.0
HFD3_k127_5453940_16 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000001553 136.0
HFD3_k127_5453940_17 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000000002244 117.0
HFD3_k127_5453940_18 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000001789 121.0
HFD3_k127_5453940_19 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum K13626 - - 0.00000000000000000004251 95.0
HFD3_k127_5453940_2 PA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 455.0
HFD3_k127_5453940_20 Protein conserved in bacteria - - - 0.0000000000000004632 91.0
HFD3_k127_5453940_21 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 - - 0.000000000000002502 78.0
HFD3_k127_5453940_22 Protein tyrosine kinase K08884,K12132 - 2.7.11.1 0.00000000000001763 79.0
HFD3_k127_5453940_23 Putative regulatory protein - - - 0.0000000000008206 70.0
HFD3_k127_5453940_3 Periplasmic component of the Tol biopolymer transport system K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 431.0
HFD3_k127_5453940_4 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 379.0
HFD3_k127_5453940_5 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 348.0
HFD3_k127_5453940_6 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 299.0
HFD3_k127_5453940_7 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004386 297.0
HFD3_k127_5453940_8 thiolester hydrolase activity K01179,K06889,K10773,K15853 - 3.2.1.4,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001103 282.0
HFD3_k127_5453940_9 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000006584 255.0
HFD3_k127_5455443_0 PFAM Type II secretion system protein E K02454 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 337.0
HFD3_k127_5455443_1 Methyltransferase K15256 - - 0.000000000000000000000000000000000000000000000001838 182.0
HFD3_k127_5455443_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000009318 83.0
HFD3_k127_5467791_0 RNA secondary structure unwinding K03724 - - 0.0 1849.0
HFD3_k127_5467791_1 Belongs to the aldehyde dehydrogenase family K00130,K00135,K09472,K22187 - 1.2.1.16,1.2.1.20,1.2.1.79,1.2.1.8,1.2.1.99 1.848e-199 634.0
HFD3_k127_5467791_2 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 355.0
HFD3_k127_5467791_3 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 362.0
HFD3_k127_5467791_4 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 306.0
HFD3_k127_5467791_5 dienelactone hydrolase K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009413 295.0
HFD3_k127_5467791_6 Protein of Unknown function (DUF2784) - - - 0.00000000000000000000000000000000000000002193 158.0
HFD3_k127_5467791_7 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000992 128.0
HFD3_k127_5467791_8 pyrroloquinoline quinone binding - - - 0.0000000000000003734 91.0
HFD3_k127_548748_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 1.631e-246 775.0
HFD3_k127_548748_1 PFAM UvrD REP helicase K03657 - 3.6.4.12 5.312e-227 725.0
HFD3_k127_548748_2 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008755 308.0
HFD3_k127_548748_3 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000004872 248.0
HFD3_k127_548748_4 ethanolamine catabolic process K04027 - - 0.000000000000000000000000000000000000000001209 157.0
HFD3_k127_548748_5 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028,K08697 - - 0.00000000000000000000000000000000006976 134.0
HFD3_k127_548748_6 - - - - 0.0000000000000000000000005992 115.0
HFD3_k127_548748_7 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.000000000003651 72.0
HFD3_k127_548748_8 cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.0001543 52.0
HFD3_k127_5509722_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000009597 254.0
HFD3_k127_5509722_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000004163 231.0
HFD3_k127_5509722_2 Adenylate cyclase - - - 0.00000000000000000000000000000000327 145.0
HFD3_k127_5515483_0 Alpha-2-Macroglobulin K06894 - - 0.0 1350.0
HFD3_k127_5515483_1 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 609.0
HFD3_k127_5515483_2 Protein of unknown function (DUF1175) K09934 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005756 269.0
HFD3_k127_5515483_3 DNA topological change K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000008633 253.0
HFD3_k127_5515483_4 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000006175 226.0
HFD3_k127_5515483_5 - - - - 0.0000000000000000000000000000003292 133.0
HFD3_k127_5515483_6 - - - - 0.00000000000000000000000001726 122.0
HFD3_k127_5515483_7 Protein of unknown function (DUF1595) - - - 0.0000000000000000000002067 100.0
HFD3_k127_5531523_0 PrkA AAA domain K07180 - - 6.815e-313 971.0
HFD3_k127_5531523_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007718 477.0
HFD3_k127_5531523_2 regulatory protein, MerR - - - 0.000000000000000000000000000001137 128.0
HFD3_k127_5531523_3 Cytochrome c, class I K05301 - 1.8.2.1 0.0001765 53.0
HFD3_k127_5531523_4 Cytochrome c - - - 0.0004148 51.0
HFD3_k127_5533078_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000453 420.0
HFD3_k127_5533078_1 - - - - 0.000000000000000000000000000000000000001968 162.0
HFD3_k127_5552324_0 amino acid - - - 0.0 1040.0
HFD3_k127_5552324_1 transcription factor binding K02584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008558 557.0
HFD3_k127_5552324_14 Belongs to the P(II) protein family K04751,K04752 - - 0.0005941 48.0
HFD3_k127_5552324_2 molybdate abc transporter K02018,K15496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004436 316.0
HFD3_k127_5552324_3 Two component transcriptional regulator, winged helix family K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 314.0
HFD3_k127_5552324_4 Bacterial extracellular solute-binding protein K02020 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004174 278.0
HFD3_k127_5552324_5 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002968 276.0
HFD3_k127_5552324_6 YVTN family beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000049 267.0
HFD3_k127_5552324_7 Histidine kinase K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000002307 218.0
HFD3_k127_5552324_8 Outer membrane protein beta-barrel domain - - - 0.00000000000000000000000000000000007247 145.0
HFD3_k127_5552324_9 RDD family - - - 0.00000000000000000000000000000003436 132.0
HFD3_k127_5554222_0 coenzyme binding K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 370.0
HFD3_k127_5554222_4 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000005021 142.0
HFD3_k127_5554222_5 Belongs to the DNA photolyase family K01669 - 4.1.99.3 0.00000006864 53.0
HFD3_k127_5563679_0 Dehydrogenase - - - 7.052e-215 687.0
HFD3_k127_5563679_1 ATP dependent DNA ligase C terminal region K10747 GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 496.0
HFD3_k127_5563679_10 PFAM Uncharacterised BCR, COG1649 K01448 - 3.5.1.28 0.0000000000000000000000000000001536 132.0
HFD3_k127_5563679_11 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000002122 131.0
HFD3_k127_5563679_12 Protein of unknown function (DUF3738) - - - 0.00006773 51.0
HFD3_k127_5563679_2 Phosphate transport system permease K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 350.0
HFD3_k127_5563679_3 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000888 331.0
HFD3_k127_5563679_4 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 342.0
HFD3_k127_5563679_5 PBP superfamily domain K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001182 280.0
HFD3_k127_5563679_6 PFAM response regulator receiver K07657,K07664 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008783 254.0
HFD3_k127_5563679_7 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000671 240.0
HFD3_k127_5563679_8 domain protein K14194 - - 0.000000000000000000000000000000000000000000000000000001672 213.0
HFD3_k127_5563679_9 - K02172 - - 0.0000000000000000000000000000000000000000000000000000465 196.0
HFD3_k127_5563831_0 Cytochrome c - - - 1.311e-204 642.0
HFD3_k127_5563831_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004019 246.0
HFD3_k127_5563831_2 Protein of unknown function (DUF1810) - - - 0.00000000000000000000000000000000000000000000000000002349 192.0
HFD3_k127_5563831_3 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000001163 206.0
HFD3_k127_5563831_4 Uncharacterized conserved protein (DUF2196) - - - 0.0000000000000000000009367 96.0
HFD3_k127_5564179_0 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 525.0
HFD3_k127_5564179_1 belongs to the thioredoxin family K05838 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007459 458.0
HFD3_k127_5564179_2 Tetratricopeptide repeat - - - 0.00000000000006319 85.0
HFD3_k127_5564179_3 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.000002636 60.0
HFD3_k127_5565091_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 4.841e-261 823.0
HFD3_k127_5565091_1 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007874 445.0
HFD3_k127_5565091_10 toxin-antitoxin pair type II binding - - - 0.000000000000000003866 88.0
HFD3_k127_5565091_11 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000006111 75.0
HFD3_k127_5565091_2 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007728 424.0
HFD3_k127_5565091_3 Phosphate sensor histidine kinase, HAMP and PAS domain-containing K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008862 346.0
HFD3_k127_5565091_4 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004577 274.0
HFD3_k127_5565091_5 2Fe-2S -binding domain protein K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000001173 244.0
HFD3_k127_5565091_6 COGs COG1392 Phosphate transport regulator (distant homolog of PhoU) K07220 - - 0.0000000000000000000000000000000000000007406 155.0
HFD3_k127_5565091_7 - - - - 0.0000000000000000000000000000000336 136.0
HFD3_k127_5565091_8 - - - - 0.000000000000000000007737 96.0
HFD3_k127_5565091_9 - - - - 0.00000000000000000001896 99.0
HFD3_k127_5576119_0 Dehydrogenase K00117 - 1.1.5.2 6.671e-221 706.0
HFD3_k127_5576119_1 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 587.0
HFD3_k127_5576119_11 - - - - 0.00000000000000000002053 111.0
HFD3_k127_5576119_12 domain protein K14194 - - 0.000000000000004408 80.0
HFD3_k127_5576119_13 Carboxypeptidase regulatory-like domain - - - 0.00000000000006886 79.0
HFD3_k127_5576119_14 function. Source PGD - - - 0.00001489 55.0
HFD3_k127_5576119_15 LysR substrate binding domain - - - 0.0007843 43.0
HFD3_k127_5576119_2 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003669 533.0
HFD3_k127_5576119_3 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 436.0
HFD3_k127_5576119_4 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007207 415.0
HFD3_k127_5576119_5 peroxiredoxin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 347.0
HFD3_k127_5576119_6 antibiotic catabolic process K01317,K02674,K07004,K11016,K13277,K20276,K21449 - 3.4.21.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000007367 295.0
HFD3_k127_5576119_7 AMP-binding enzyme C-terminal domain K18660 - - 0.000000000000000000000000000000000000000000000000000000000000000006595 227.0
HFD3_k127_5576119_8 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000004848 231.0
HFD3_k127_5576119_9 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000000001186 163.0
HFD3_k127_5584040_0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 4.039e-252 800.0
HFD3_k127_5584040_1 Belongs to the heme-copper respiratory oxidase family K02274 - 1.9.3.1 1.764e-220 698.0
HFD3_k127_5584040_10 Protein of unknown function (DUF2585) - - - 0.00000000000000000000000000000000000000000003952 166.0
HFD3_k127_5584040_11 Protein of unknown function (DUF1003) - - - 0.00000000000000000000000000000000000000001341 159.0
HFD3_k127_5584040_12 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000002678 151.0
HFD3_k127_5584040_13 Belongs to the UPF0337 (CsbD) family - - - 0.0000000000000000000000922 98.0
HFD3_k127_5584040_14 PFAM Transport-associated - - - 0.000000000000000001013 94.0
HFD3_k127_5584040_15 - - - - 0.0000000000000000818 81.0
HFD3_k127_5584040_18 - - - - 0.000003452 52.0
HFD3_k127_5584040_2 Sucrose-6F-phosphate phosphohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 604.0
HFD3_k127_5584040_3 transferase activity, transferring glycosyl groups K00713,K06338 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 445.0
HFD3_k127_5584040_4 and related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000432 451.0
HFD3_k127_5584040_5 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 373.0
HFD3_k127_5584040_6 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000001254 256.0
HFD3_k127_5584040_7 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001798 256.0
HFD3_k127_5584040_8 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K02275 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 0.000000000000000000000000000000000000000000000000000000008227 209.0
HFD3_k127_5584040_9 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000001066 199.0
HFD3_k127_5594366_0 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 456.0
HFD3_k127_5594366_1 PQQ enzyme repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003626 310.0
HFD3_k127_5594366_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009049 277.0
HFD3_k127_5594366_3 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.00000000000000000000000000000000000005837 154.0
HFD3_k127_5633752_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 572.0
HFD3_k127_5633752_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000436 496.0
HFD3_k127_5633752_10 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.000000000000000000000000000000000000000000000000000000000000004228 224.0
HFD3_k127_5633752_11 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.0000000000000000000000000000000000000000000000000000000003456 203.0
HFD3_k127_5633752_12 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000007629 206.0
HFD3_k127_5633752_13 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000000000002321 190.0
HFD3_k127_5633752_14 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000002642 190.0
HFD3_k127_5633752_15 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000000009793 188.0
HFD3_k127_5633752_16 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000001291 194.0
HFD3_k127_5633752_17 Involved in the binding of tRNA to the ribosomes K02946 - - 0.00000000000000000000000000000000000000000000000000646 183.0
HFD3_k127_5633752_18 binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000001112 161.0
HFD3_k127_5633752_19 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000000002149 147.0
HFD3_k127_5633752_2 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 407.0
HFD3_k127_5633752_20 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.00000000000000000000000000000000000005573 145.0
HFD3_k127_5633752_21 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000000000000009497 147.0
HFD3_k127_5633752_22 Ribosomal protein L17 K02879 - - 0.0000000000000000000000000000000000002092 148.0
HFD3_k127_5633752_23 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000000000006008 134.0
HFD3_k127_5633752_24 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000000000000004419 127.0
HFD3_k127_5633752_25 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.000000000000000000000000003072 117.0
HFD3_k127_5633752_26 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000004315 101.0
HFD3_k127_5633752_27 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000002404 94.0
HFD3_k127_5633752_28 Ribosomal protein L30 K02907 - - 0.00000000000001113 78.0
HFD3_k127_5633752_29 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000001725 72.0
HFD3_k127_5633752_3 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009468 351.0
HFD3_k127_5633752_30 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.0000001456 57.0
HFD3_k127_5633752_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007557 327.0
HFD3_k127_5633752_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 292.0
HFD3_k127_5633752_6 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006924 274.0
HFD3_k127_5633752_7 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005972 272.0
HFD3_k127_5633752_8 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000000000000000000000009994 227.0
HFD3_k127_5633752_9 Belongs to the universal ribosomal protein uS5 family K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000001495 222.0
HFD3_k127_5637521_0 Glycosyltransferase family 87 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 389.0
HFD3_k127_5637521_1 Cys/Met metabolism PLP-dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003269 297.0
HFD3_k127_5638224_0 MacB-like periplasmic core domain - - - 0.0 1020.0
HFD3_k127_5638224_1 metallopeptidase activity K06212,K06402 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016021,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0031224,GO:0031226,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006235 381.0
HFD3_k127_5638224_2 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000001715 208.0
HFD3_k127_5638224_3 Universal stress protein - - - 0.00000000000000000000000000003554 128.0
HFD3_k127_5638224_4 negative regulation of transcription, DNA-templated - - - 0.0000000000000007538 78.0
HFD3_k127_5650121_0 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000007758 113.0
HFD3_k127_5650121_1 arylformamidase activity - - - 0.0000000000000000000004673 107.0
HFD3_k127_5650121_2 - - - - 0.000000000004499 72.0
HFD3_k127_5660640_0 PFAM Rh family protein ammonium transporter K03320 - - 1.539e-232 730.0
HFD3_k127_5660640_1 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000001142 244.0
HFD3_k127_5660640_2 response regulator K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000003968 231.0
HFD3_k127_5666094_0 FAD-binding domain K00529 - 1.18.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009632 384.0
HFD3_k127_5666094_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000913 340.0
HFD3_k127_5666094_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002988 285.0
HFD3_k127_5666094_3 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000002069 74.0
HFD3_k127_5666094_4 Involved in the tonB-independent uptake of proteins - - - 0.00009934 55.0
HFD3_k127_5685128_0 Glutamine amidotransferase of anthranilate synthase K13950 - 2.6.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 390.0
HFD3_k127_5685128_1 Pfam:DUF59 - - - 0.0000000000000000000000000000000000000000000000000002144 191.0
HFD3_k127_5685128_2 Urate oxidase N-terminal - - - 0.000000000000000000000000000001229 129.0
HFD3_k127_5702995_0 Sigma-54 interaction domain K02584,K07713,K15836,K21009 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004036 508.0
HFD3_k127_5702995_1 PFAM conserved - - - 0.00000002001 59.0
HFD3_k127_572524_0 COG3754 Lipopolysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 527.0
HFD3_k127_572524_1 Wzt C-terminal domain K09691 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005172 429.0
HFD3_k127_5762574_0 PQQ-like domain - - - 9.228e-196 621.0
HFD3_k127_5762574_1 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009009 297.0
HFD3_k127_5762574_2 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000008685 251.0
HFD3_k127_5776441_0 Dihydrouridine synthase (Dus) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005241 426.0
HFD3_k127_5776441_1 Ankyrin repeats (many copies) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003155 270.0
HFD3_k127_5776441_2 macromolecule localization K09690 - - 0.00000000000000000000000000000000000000000000000000305 192.0
HFD3_k127_5783096_0 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005959 415.0
HFD3_k127_5783096_1 - - - - 0.00000000000000000000000000000000000000000000000000000000104 213.0
HFD3_k127_5783096_2 - - - - 0.0000000000000000000000000000000000000000000000000000005548 201.0
HFD3_k127_5783096_3 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000002756 168.0
HFD3_k127_5783096_4 HEAT repeats - - - 0.000000000000000000000000000000000000002885 160.0
HFD3_k127_5798518_0 xanthine dehydrogenase activity K07303 - 1.3.99.16 4.018e-221 707.0
HFD3_k127_5798518_1 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004521 592.0
HFD3_k127_5798518_10 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005522 298.0
HFD3_k127_5798518_11 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005778 270.0
HFD3_k127_5798518_12 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004342 278.0
HFD3_k127_5798518_13 Cytochrome c K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005401 269.0
HFD3_k127_5798518_14 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000005667 242.0
HFD3_k127_5798518_15 Lysin motif K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000001499 237.0
HFD3_k127_5798518_16 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000003467 231.0
HFD3_k127_5798518_17 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000003584 231.0
HFD3_k127_5798518_18 Integral membrane protein TerC family - - - 0.00000000000000000000000000000000000000000000000002265 186.0
HFD3_k127_5798518_19 - - - - 0.00000000000000000000000000000000000000000000000002455 186.0
HFD3_k127_5798518_2 PFAM delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 441.0
HFD3_k127_5798518_20 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000002489 175.0
HFD3_k127_5798518_21 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.000000000000000000000000000000000000000001736 175.0
HFD3_k127_5798518_22 Polysaccharide lyase family 4, domain II - - - 0.00000000000000000000000000000000000000001513 163.0
HFD3_k127_5798518_23 N-Acetylmuramoyl-L-alanine amidase K01447,K03806,K11066 - 3.5.1.28 0.000000000000000000000000000000000000002295 153.0
HFD3_k127_5798518_24 phosphotransferase activity, carboxyl group as acceptor - - - 0.0000000000000000000000000000000000001984 149.0
HFD3_k127_5798518_25 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000408 148.0
HFD3_k127_5798518_26 Cytochrome C' - - - 0.000000000000000000000000000000005709 136.0
HFD3_k127_5798518_27 cell redox homeostasis - - - 0.000000000000000000000000000000006198 134.0
HFD3_k127_5798518_28 membrane - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000004938 134.0
HFD3_k127_5798518_29 transposase IS116 IS110 IS902 family protein K07486 - - 0.0000000000000000000000000002094 121.0
HFD3_k127_5798518_3 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 400.0
HFD3_k127_5798518_31 Methyltransferase type 11 - - - 0.0000000000000001338 89.0
HFD3_k127_5798518_32 COG0346 Lactoylglutathione lyase and related lyases - - - 0.00000000000002585 79.0
HFD3_k127_5798518_33 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000005311 56.0
HFD3_k127_5798518_34 - - - - 0.000000124 59.0
HFD3_k127_5798518_35 RDD family - - - 0.0000001529 59.0
HFD3_k127_5798518_36 Cell wall-active antibiotics response 4TMS YvqF K11622 - - 0.000008454 53.0
HFD3_k127_5798518_4 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 369.0
HFD3_k127_5798518_5 PFAM Integral membrane protein TerC K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 358.0
HFD3_k127_5798518_6 Belongs to the GPI family K01810 - 5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006177 356.0
HFD3_k127_5798518_7 4 iron, 4 sulfur cluster binding K07139 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464,GO:0048037,GO:0051536,GO:0051539,GO:0051540 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 339.0
HFD3_k127_5798518_8 PFAM Organic solvent tolerance protein K04744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 338.0
HFD3_k127_5798518_9 LytTr DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 302.0
HFD3_k127_581479_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 631.0
HFD3_k127_581479_1 Tex-like protein N-terminal domain K06959 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004737 622.0
HFD3_k127_581479_10 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008968 258.0
HFD3_k127_581479_11 Aminotransferase K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000001248 224.0
HFD3_k127_581479_12 membrane protein (homolog of Drosophila rhomboid) K19225 - 3.4.21.105 0.00000000000000000000000000000000000000000000000551 186.0
HFD3_k127_581479_13 domain protein - - - 0.00000000000000000000000000000000000000000000001094 193.0
HFD3_k127_581479_14 DoxX-like family - - - 0.00000000000000000000000000000000000000000000004962 173.0
HFD3_k127_581479_15 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.00000000000000000000000000000000000000006891 152.0
HFD3_k127_581479_16 PFAM Phosphoribosyltransferase - - - 0.000000000000000000000000000000000001325 147.0
HFD3_k127_581479_17 YCII-related domain - - - 0.0000000000000000000000000000000000579 137.0
HFD3_k127_581479_18 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.00000000000000000000000000000000104 137.0
HFD3_k127_581479_19 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000001498 121.0
HFD3_k127_581479_2 acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 556.0
HFD3_k127_581479_20 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000000000000001539 123.0
HFD3_k127_581479_21 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000000004007 119.0
HFD3_k127_581479_22 DinB family - - - 0.000000000000000000000000003072 117.0
HFD3_k127_581479_23 - - - - 0.00000000000000000002867 103.0
HFD3_k127_581479_24 - - - - 0.0000000000000004897 83.0
HFD3_k127_581479_26 Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)- L-lysine intermediate to form hypusine, an essential post- translational modification only found in mature eIF-5A factor K06072 GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016491,GO:0016705,GO:0018193,GO:0018205,GO:0019135,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0055114,GO:0071704,GO:1901564 1.14.99.29 0.0001165 54.0
HFD3_k127_581479_3 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 512.0
HFD3_k127_581479_4 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003299 419.0
HFD3_k127_581479_5 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007937 369.0
HFD3_k127_581479_6 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 366.0
HFD3_k127_581479_7 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 306.0
HFD3_k127_581479_8 PFAM Response regulator receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005429 279.0
HFD3_k127_581479_9 Cation efflux family K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008218 261.0
HFD3_k127_5829687_0 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000338 284.0
HFD3_k127_5829687_1 AMP binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007945 247.0
HFD3_k127_5829687_2 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000004323 241.0
HFD3_k127_5829687_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05825 - - 0.00000000000000000000000000000000000000000000000000000001547 202.0
HFD3_k127_5829687_5 Prokaryotic dksA/traR C4-type zinc finger - - - 0.000000000000000000002821 97.0
HFD3_k127_5829687_6 ATP-dependent Clp protease adaptor protein ClpS K06891 - - 0.00000000000000000001275 94.0
HFD3_k127_5832840_0 Iron-containing alcohol dehydrogenase K11173 - 1.1.99.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 463.0
HFD3_k127_5832840_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 487.0
HFD3_k127_5832840_2 PFAM Beta-lactamase K18988 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007169 444.0
HFD3_k127_5832840_3 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000000000000000001202 196.0
HFD3_k127_5832840_4 SMP-30/Gluconolaconase/LRE-like region - - - 0.0000000000000000000000000000000000001517 156.0
HFD3_k127_5832840_5 - - - - 0.0000000000000000000000000001 122.0
HFD3_k127_5832840_6 helix_turn_helix, Lux Regulon - - - 0.0000003538 61.0
HFD3_k127_5834219_0 PFAM CBS domain containing protein K01697,K01738 - 2.5.1.47,4.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000858 492.0
HFD3_k127_5834219_1 Putative citrate transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 477.0
HFD3_k127_5834219_2 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000631 462.0
HFD3_k127_5834219_3 Belongs to the cysteine synthase cystathionine beta- synthase family K01738,K12339,K21949 - 2.5.1.140,2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 316.0
HFD3_k127_5834219_4 WYL domain K13572 - - 0.000000000000000000000000000000000000000000000000000007352 203.0
HFD3_k127_5834219_5 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000002824 135.0
HFD3_k127_5834219_6 Amidohydrolase family - - - 0.00000000000000000000000226 116.0
HFD3_k127_5900722_0 PFAM ABC transporter related K06020 - 3.6.3.25 5.265e-298 921.0
HFD3_k127_5900722_1 6-phosphogluconate dehydrogenase K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003672 408.0
HFD3_k127_5900722_2 Associated with various cellular activities K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008078 378.0
HFD3_k127_5900722_3 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007785 311.0
HFD3_k127_5900722_4 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000002264 224.0
HFD3_k127_5900722_5 Belongs to the FGGY kinase family K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000004921 184.0
HFD3_k127_5900722_6 PFAM glycosyl transferase family 39 - - - 0.000000000000000000000000000000000000000004091 174.0
HFD3_k127_5900722_7 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000000000000000002284 99.0
HFD3_k127_5906706_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006065 555.0
HFD3_k127_5906706_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005344 530.0
HFD3_k127_5906706_10 with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine K01664 GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006575,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009108,GO:0009308,GO:0009309,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042398,GO:0042401,GO:0042430,GO:0042435,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000001833 264.0
HFD3_k127_5906706_11 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004253 269.0
HFD3_k127_5906706_12 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000001261 260.0
HFD3_k127_5906706_13 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000202 248.0
HFD3_k127_5906706_14 TIGRFAM phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000003708 243.0
HFD3_k127_5906706_15 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000001054 238.0
HFD3_k127_5906706_16 imidazoleglycerol-phosphate dehydratase K00817,K01089,K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.9,3.1.3.15,4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000001439 242.0
HFD3_k127_5906706_17 Phosphoribosyl-AMP cyclohydrolase K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000000000000000000000136 227.0
HFD3_k127_5906706_18 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.000000000000000000000000000000000000000000000000000000000001055 219.0
HFD3_k127_5906706_19 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000003447 209.0
HFD3_k127_5906706_2 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002308 388.0
HFD3_k127_5906706_20 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000008911 188.0
HFD3_k127_5906706_21 Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000007946 173.0
HFD3_k127_5906706_22 Chorismate mutase type II - - - 0.000000000000000002529 88.0
HFD3_k127_5906706_3 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 365.0
HFD3_k127_5906706_4 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008851 342.0
HFD3_k127_5906706_5 Coenzyme A transferase K01028 - 2.8.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 335.0
HFD3_k127_5906706_6 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 332.0
HFD3_k127_5906706_7 Coenzyme A transferase K01029 - 2.8.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002661 321.0
HFD3_k127_5906706_8 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001115 274.0
HFD3_k127_5906706_9 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000001676 280.0
HFD3_k127_5908108_0 Sodium:dicarboxylate symporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 417.0
HFD3_k127_5908108_1 mandelate racemase muconate lactonizing K01684,K01781,K08323 - 4.2.1.6,4.2.1.8,5.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000001308 262.0
HFD3_k127_5908108_2 lactoylglutathione lyase activity K03088 - - 0.00000000000000000000000000000000000000000000002684 180.0
HFD3_k127_5958942_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 465.0
HFD3_k127_5958942_1 Phage shock protein C, PspC K03973 - - 0.0000000000000000000000015 106.0
HFD3_k127_5958942_2 Putative auto-transporter adhesin, head GIN domain - - - 0.00000000000000000004934 101.0
HFD3_k127_5958942_4 TPR repeat-containing protein - - - 0.0000001899 64.0
HFD3_k127_5964706_0 von Willebrand factor, type A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002805 468.0
HFD3_k127_5964706_1 dna ligase K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009742 400.0
HFD3_k127_5964706_10 von Willebrand factor (vWF) type A domain K07114 - - 0.000000000000000000000000000259 127.0
HFD3_k127_5964706_11 Periplasmic or secreted lipoprotein - - - 0.00000000000000000000000000348 119.0
HFD3_k127_5964706_12 - - - - 0.00000000000000000000000007926 119.0
HFD3_k127_5964706_13 Alkyl hydroperoxide reductase - - - 0.00000000000000000000001139 114.0
HFD3_k127_5964706_14 - - - - 0.000000009937 65.0
HFD3_k127_5964706_15 bacterial OsmY and nodulation domain K04065 GO:0005575,GO:0005623,GO:0006457,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0009628,GO:0009987,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0050896,GO:0061077 - 0.0000001736 60.0
HFD3_k127_5964706_16 Carboxypeptidase regulatory-like domain K14475 - - 0.000008018 58.0
HFD3_k127_5964706_17 RNA recognition motif K14837 GO:0000375,GO:0000377,GO:0000398,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005847,GO:0005849,GO:0006139,GO:0006351,GO:0006353,GO:0006366,GO:0006369,GO:0006379,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016604,GO:0018130,GO:0019438,GO:0031123,GO:0031124,GO:0031974,GO:0031981,GO:0032774,GO:0032991,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0071920,GO:0090304,GO:0090305,GO:0090501,GO:0097159,GO:0097659,GO:0098787,GO:0098789,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.0001317 49.0
HFD3_k127_5964706_18 nuclear chromosome segregation K03631,K09971,K13582 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 - 0.00049 53.0
HFD3_k127_5964706_2 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 406.0
HFD3_k127_5964706_3 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001407 278.0
HFD3_k127_5964706_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001052 252.0
HFD3_k127_5964706_5 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000002139 247.0
HFD3_k127_5964706_6 lactoylglutathione lyase activity K03088 - - 0.00000000000000000000000000000000000000000000000000000000000001026 226.0
HFD3_k127_5964706_7 Haem-degrading - - - 0.000000000000000000000000000000000000000003917 160.0
HFD3_k127_5964706_8 Aerotolerance regulator N-terminal - - - 0.0000000000000000000000000000007805 139.0
HFD3_k127_5964706_9 hyperosmotic response - - - 0.00000000000000000000000000002448 132.0
HFD3_k127_5997805_0 PQQ-like domain K00114 - 1.1.2.8 6.438e-246 770.0
HFD3_k127_5997805_1 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 375.0
HFD3_k127_5997805_10 acetyltransferase - - - 0.00000002358 58.0
HFD3_k127_5997805_2 DNA topological change K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 325.0
HFD3_k127_5997805_3 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 310.0
HFD3_k127_5997805_4 Ankyrin repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004017 268.0
HFD3_k127_5997805_5 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000001055 208.0
HFD3_k127_5997805_6 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000006273 191.0
HFD3_k127_5997805_7 Carboxylesterase family - - - 0.00000000000000000000000000000000104 145.0
HFD3_k127_5997805_8 DinB family - - - 0.0000000000000000006072 93.0
HFD3_k127_5997805_9 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000003494 63.0
HFD3_k127_6000822_0 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 2.648e-310 964.0
HFD3_k127_6000822_1 Helix-hairpin-helix domain K04477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002488 267.0
HFD3_k127_6000822_2 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000563 93.0
HFD3_k127_6004393_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 6.48e-307 950.0
HFD3_k127_6004393_1 PFAM glycoside hydrolase family 77 K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006287 514.0
HFD3_k127_6004393_10 Siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.00000000000000000000000000000000000000001258 168.0
HFD3_k127_6004393_11 Uroporphyrinogen-III synthase K01719 - 4.2.1.75 0.000000000000000000000000000000000000006035 155.0
HFD3_k127_6004393_12 RNA-binding protein - - - 0.000000000000000002031 93.0
HFD3_k127_6004393_2 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005458 436.0
HFD3_k127_6004393_3 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 428.0
HFD3_k127_6004393_4 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 416.0
HFD3_k127_6004393_5 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008795 260.0
HFD3_k127_6004393_6 TPM domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001228 256.0
HFD3_k127_6004393_7 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02303 - 2.1.1.107 0.0000000000000000000000000000000000000000000000000000000000000001468 229.0
HFD3_k127_6004393_8 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.00000000000000000000000000000000000000000000004979 177.0
HFD3_k127_6004393_9 - - - - 0.0000000000000000000000000000000000000000001829 164.0
HFD3_k127_6009192_0 Site-specific recombinase, DNA invertase Pin - - - 1.07e-251 794.0
HFD3_k127_6009192_1 Integrase core domain - - - 0.000000000000000000005187 100.0
HFD3_k127_6009192_3 ASPIC and UnbV - - - 0.0000000000004387 71.0
HFD3_k127_601002_0 Carboxyl transferase domain K01969 - 6.4.1.4 4.334e-236 740.0
HFD3_k127_601002_1 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 6.507e-235 741.0
HFD3_k127_601002_10 - - - - 0.0000000000000000000000000000000000000000001433 163.0
HFD3_k127_601002_11 PFAM thioesterase superfamily K07107 - - 0.00000000000000000000000000000000002149 138.0
HFD3_k127_601002_12 Calcineurin-like phosphoesterase - - - 0.00000000000000000000002016 112.0
HFD3_k127_601002_14 TIGRFAM competence protein ComEA helix-hairpin-helix K02237 - - 0.0000000000001174 74.0
HFD3_k127_601002_15 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.000000006915 62.0
HFD3_k127_601002_2 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 582.0
HFD3_k127_601002_3 acyl-CoA dehydrogenase activity K00252 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.3.8.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 524.0
HFD3_k127_601002_4 HMGL-like K01640 GO:0003674,GO:0003824,GO:0004419,GO:0005488,GO:0016829,GO:0016830,GO:0016833,GO:0043167,GO:0043169,GO:0046872 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009582 330.0
HFD3_k127_601002_5 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000813 332.0
HFD3_k127_601002_6 Enoyl-CoA hydratase K13766 - 4.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000007074 247.0
HFD3_k127_601002_7 - - - - 0.0000000000000000000000000000000000000000000000000000000006032 211.0
HFD3_k127_601002_8 B12 binding domain K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000001806 198.0
HFD3_k127_601002_9 Acid phosphatase homologues - - - 0.000000000000000000000000000000000000000000000004797 184.0
HFD3_k127_6101689_0 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005151 302.0
HFD3_k127_6101689_1 Beta-lactamase K01286 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000006408 265.0
HFD3_k127_6101689_2 dehydrogenase domain of multifunctional non-ribosomal peptide - - - 0.00000000000000000000000000000000000000000000000000001056 203.0
HFD3_k127_6101689_3 Protein of unknown function (DUF1572) - - - 0.000000000000000000000000000000000000001345 153.0
HFD3_k127_6101689_4 Monogalactosyldiacylglycerol synthase K03429 - 2.4.1.315 0.0000000000000000000000007564 117.0
HFD3_k127_6101689_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000006064 94.0
HFD3_k127_6101689_6 domain-containing protein K16726 GO:0000785,GO:0001568,GO:0001654,GO:0001745,GO:0001751,GO:0001754,GO:0001817,GO:0001819,GO:0001944,GO:0001955,GO:0002376,GO:0002682,GO:0002684,GO:0002697,GO:0002699,GO:0002831,GO:0002833,GO:0003674,GO:0003682,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005694,GO:0005737,GO:0006275,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0006996,GO:0007005,GO:0007010,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007275,GO:0007346,GO:0007399,GO:0007423,GO:0007492,GO:0008150,GO:0009605,GO:0009607,GO:0009617,GO:0009653,GO:0009887,GO:0009888,GO:0009889,GO:0009892,GO:0009894,GO:0009895,GO:0009966,GO:0009967,GO:0009987,GO:0010506,GO:0010507,GO:0010556,GO:0010564,GO:0010639,GO:0010646,GO:0010647,GO:0010821,GO:0010823,GO:0010927,GO:0010941,GO:0012505,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019730,GO:0019899,GO:0019900,GO:0019901,GO:0021700,GO:0022008,GO:0022607,GO:0023051,GO:0023052,GO:0023056,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030154,GO:0030182,GO:0030239,GO:0031032,GO:0031090,GO:0031323,GO:0031324,GO:0031326,GO:0031329,GO:0031330,GO:0031347,GO:0031349,GO:0031430,GO:0031672,GO:0031674,GO:0031965,GO:0031967,GO:0031975,GO:0032101,GO:0032103,GO:0032501,GO:0032502,GO:0032989,GO:0033043,GO:0039531,GO:0039533,GO:0039535,GO:0040011,GO:0042692,GO:0042742,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043122,GO:0043123,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043292,GO:0043900,GO:0043902,GO:0044085,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044449,GO:0044464,GO:0045087,GO:0045088,GO:0045089,GO:0045214,GO:0045595,GO:0045596,GO:0045787,GO:0045931,GO:0046530,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048592,GO:0048646,GO:0048699,GO:0048731,GO:0048749,GO:0048856,GO:0048869,GO:0050688,GO:0050776,GO:0050778,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051052,GO:0051093,GO:0051128,GO:0051129,GO:0051146,GO:0051147,GO:0051148,GO:0051150,GO:0051151,GO:0051171,GO:0051239,GO:0051240,GO:0051704,GO:0051707,GO:0051716,GO:0051726,GO:0055001,GO:0055002,GO:0060255,GO:0060361,GO:0060548,GO:0061061,GO:0065007,GO:0070925,GO:0071695,GO:0071840,GO:0072358,GO:0072359,GO:0080090,GO:0080134,GO:0090068,GO:0090596,GO:0097435,GO:0098542,GO:0099080,GO:0099081,GO:0099512,GO:1900087,GO:1900245,GO:1900246,GO:1901987,GO:1901989,GO:1901990,GO:1901992,GO:1902531,GO:1902533,GO:1902806,GO:1902808,GO:1903146,GO:1903147,GO:2000045,GO:2000112 - 0.0000000002353 68.0
HFD3_k127_611786_0 MoaE protein K21142 - 2.8.1.12 0.00000000000000000000000000000000000000000000000000000000000000006019 229.0
HFD3_k127_6162384_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1132.0
HFD3_k127_6162384_1 SpoVR like protein K06415 - - 8.462e-216 679.0
HFD3_k127_6162384_10 PFAM glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001032 265.0
HFD3_k127_6162384_11 Ankyrin repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002136 260.0
HFD3_k127_6162384_12 queuosine metabolic process K04068,K10026 - 1.97.1.4,4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000001445 242.0
HFD3_k127_6162384_13 Methyltransferase type 12 - - - 0.00000000000000000000000000000000000000001338 162.0
HFD3_k127_6162384_14 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000007378 154.0
HFD3_k127_6162384_15 - - - - 0.000000000000000000000000000000001683 141.0
HFD3_k127_6162384_16 Mov34 MPN PAD-1 family protein - - - 0.00000000000000000000000004309 113.0
HFD3_k127_6162384_17 TIGRFAM MoaD family protein K03636 - - 0.000000000000000000000002083 105.0
HFD3_k127_6162384_18 PrkA AAA domain K07180 - - 0.00000000000000000266 84.0
HFD3_k127_6162384_19 Tetratricopeptide repeat - - - 0.0000001334 61.0
HFD3_k127_6162384_2 HELICc2 K03722 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004149 600.0
HFD3_k127_6162384_3 Belongs to the UPF0229 family K09786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 493.0
HFD3_k127_6162384_4 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 391.0
HFD3_k127_6162384_5 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 371.0
HFD3_k127_6162384_6 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 326.0
HFD3_k127_6162384_7 short-chain dehydrogenase reductase SDR K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 325.0
HFD3_k127_6162384_8 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003647 310.0
HFD3_k127_6162384_9 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004019 309.0
HFD3_k127_6233212_0 Belongs to the TPP enzyme family K01576,K01652 - 2.2.1.6,4.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 536.0
HFD3_k127_6233212_1 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 463.0
HFD3_k127_6233212_10 COG1112 Superfamily I DNA and RNA helicases and helicase subunits K10742 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000001823 282.0
HFD3_k127_6233212_11 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000000006249 240.0
HFD3_k127_6233212_12 RNA pseudouridylate synthase K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000002041 234.0
HFD3_k127_6233212_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000007795 228.0
HFD3_k127_6233212_14 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000002755 225.0
HFD3_k127_6233212_15 TIGRFAM TonB family protein K03832 - - 0.00000000000000000000000000000000000000000000000000000000008613 221.0
HFD3_k127_6233212_16 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000002701 202.0
HFD3_k127_6233212_17 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000007614 196.0
HFD3_k127_6233212_18 Ferredoxin K02230 - 6.6.1.2 0.0000000000000000000000000000000000000000000000007151 177.0
HFD3_k127_6233212_19 Protein conserved in bacteria K09922 - - 0.00000000000000000000000000000000000000000003415 163.0
HFD3_k127_6233212_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003972 472.0
HFD3_k127_6233212_20 HAD-superfamily hydrolase, subfamily IA, variant 1 - - - 0.000000000000000000000000000000000000000007532 161.0
HFD3_k127_6233212_21 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.000000000000000000000000000000000000005061 149.0
HFD3_k127_6233212_22 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000003596 151.0
HFD3_k127_6233212_23 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000005097 146.0
HFD3_k127_6233212_24 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000006945 152.0
HFD3_k127_6233212_25 Protein of unknown function (DUF3237) - - - 0.000000000000000000000000000000000002735 148.0
HFD3_k127_6233212_26 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000884 149.0
HFD3_k127_6233212_27 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000005189 136.0
HFD3_k127_6233212_28 4'-phosphopantetheinyl transferase superfamily K00997 - 2.7.8.7 0.000000000000000000000000000000003534 132.0
HFD3_k127_6233212_29 Thioredoxin-like - - - 0.00000000000000000000000000000001358 136.0
HFD3_k127_6233212_3 Tannase and feruloyl esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 436.0
HFD3_k127_6233212_30 Protein of unknown function (DUF952) K00799,K01560,K21420 - 2.3.2.29,2.5.1.18,3.8.1.2 0.00000000000000000000000000000006275 128.0
HFD3_k127_6233212_31 TIGRFAM TonB K03832 - - 0.00000000000000000000000002466 122.0
HFD3_k127_6233212_32 YjbR - - - 0.0000000000000000000005336 100.0
HFD3_k127_6233212_33 lactoylglutathione lyase activity K00941,K01724,K01759,K07032,K08234 - 2.7.1.49,2.7.4.7,4.2.1.96,4.4.1.5 0.000000000000000000001055 102.0
HFD3_k127_6233212_34 Domain of unknown function (DUF4252) - - - 0.000000000000000000001657 100.0
HFD3_k127_6233212_35 exonuclease activity K16899 - 3.6.4.12 0.000000000008764 79.0
HFD3_k127_6233212_36 - - - - 0.00000000001028 69.0
HFD3_k127_6233212_37 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00000000002084 72.0
HFD3_k127_6233212_38 Cytochrome c K17760 - 1.1.9.1 0.00000003274 62.0
HFD3_k127_6233212_4 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008944 382.0
HFD3_k127_6233212_5 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005048 342.0
HFD3_k127_6233212_6 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 331.0
HFD3_k127_6233212_7 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 344.0
HFD3_k127_6233212_8 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008403 308.0
HFD3_k127_6233212_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005991 310.0
HFD3_k127_6256979_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 1.662e-283 888.0
HFD3_k127_6256979_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 2.142e-209 661.0
HFD3_k127_6256979_2 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 530.0
HFD3_k127_6256979_3 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 483.0
HFD3_k127_6256979_4 COG1228 Imidazolonepropionase and related amidohydrolases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 443.0
HFD3_k127_6256979_5 - - - - 0.00000000000000000000000009513 113.0
HFD3_k127_6256979_6 Pfam Cation efflux - - - 0.000000000003662 76.0
HFD3_k127_6256979_7 FeoA K04758 - - 0.0000000001758 66.0
HFD3_k127_6256979_8 - - - - 0.0001425 47.0
HFD3_k127_6264978_0 DNA topological change K03168 - 5.99.1.2 1.827e-243 775.0
HFD3_k127_6264978_1 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004364 511.0
HFD3_k127_6264978_11 PFAM FMN-binding domain - - - 0.000000001414 66.0
HFD3_k127_6264978_12 PFAM Glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.0000001976 62.0
HFD3_k127_6264978_2 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000059 431.0
HFD3_k127_6264978_3 Ankyrin repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003222 352.0
HFD3_k127_6264978_4 SMART PAS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 346.0
HFD3_k127_6264978_5 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 321.0
HFD3_k127_6264978_6 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003306 308.0
HFD3_k127_6264978_7 TrkA-C domain K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 302.0
HFD3_k127_6264978_8 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000001778 203.0
HFD3_k127_6264978_9 4Fe-4S binding domain - - - 0.000000000000000000000000000001553 134.0
HFD3_k127_62704_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1016.0
HFD3_k127_62704_1 Oligopeptidase F K08602 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 581.0
HFD3_k127_62704_10 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000000001779 234.0
HFD3_k127_62704_11 Response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000004052 251.0
HFD3_k127_62704_12 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.00000000000000000000000000000000000000000000000000000000000000006975 229.0
HFD3_k127_62704_13 Protein conserved in bacteria - - - 0.0000000000000000000000000000001292 128.0
HFD3_k127_62704_14 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000000002585 117.0
HFD3_k127_62704_16 metal-dependent hydrolase with the TIM-barrel fold - - - 0.00000001235 68.0
HFD3_k127_62704_17 COG2198 FOG HPt domain K20976 - - 0.000006327 51.0
HFD3_k127_62704_18 PBS lyase - - - 0.00004514 55.0
HFD3_k127_62704_2 coenzyme binding K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004255 455.0
HFD3_k127_62704_3 Glycosyl transferase family group 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 441.0
HFD3_k127_62704_4 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006655 337.0
HFD3_k127_62704_5 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 324.0
HFD3_k127_62704_6 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004911 294.0
HFD3_k127_62704_7 GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 308.0
HFD3_k127_62704_8 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001015 267.0
HFD3_k127_62704_9 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001484 276.0
HFD3_k127_62852_0 Alpha-L-arabinofuranosidase C-terminus - - - 4.087e-205 660.0
HFD3_k127_62852_1 TIGRFAM galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007123 460.0
HFD3_k127_62852_10 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000001754 116.0
HFD3_k127_62852_12 - - - - 0.0006591 45.0
HFD3_k127_62852_2 Large family of predicted nucleotide-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 455.0
HFD3_k127_62852_3 Galactokinase galactose-binding signature K00849 - 2.7.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008042 426.0
HFD3_k127_62852_4 ABC-type sugar transport system periplasmic component K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000993 392.0
HFD3_k127_62852_5 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000000004178 251.0
HFD3_k127_62852_6 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.00000000000000000000000000000000000000000000000000000000003633 212.0
HFD3_k127_62852_7 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000003001 173.0
HFD3_k127_62852_8 - - - - 0.000000000000000000000000000000132 128.0
HFD3_k127_62852_9 - - - - 0.0000000000000000000000000000001844 134.0
HFD3_k127_6305577_0 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.2.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006029 428.0
HFD3_k127_6305577_1 Amidohydrolase family K12960,K20810 - 3.5.4.28,3.5.4.31,3.5.4.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 304.0
HFD3_k127_6305577_2 TIGRFAM MazG family protein K02428,K04765 - 3.6.1.66,3.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 288.0
HFD3_k127_6305577_3 GlcNAc-PI de-N-acetylase K01463 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002577 257.0
HFD3_k127_6305577_4 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000216 254.0
HFD3_k127_6305577_5 mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000001603 226.0
HFD3_k127_6305577_6 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000006852 188.0
HFD3_k127_6305577_7 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000009653 72.0
HFD3_k127_6313292_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005906 468.0
HFD3_k127_6313292_1 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 453.0
HFD3_k127_6313292_2 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 398.0
HFD3_k127_6313292_3 two component, sigma54 specific, transcriptional regulator, Fis family K07713,K07714,K07715 - - 0.000000000000000000000000000000000000000000000000000000000000000000005201 247.0
HFD3_k127_6313292_4 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000003679 228.0
HFD3_k127_6313292_5 protein tyrosine phosphatase activity K01104 - 3.1.3.48 0.000000000000000000000000000000000000000000000000000224 195.0
HFD3_k127_6313292_6 outer membrane autotransporter barrel domain protein - - - 0.0000000000000000000000000000000000004067 147.0
HFD3_k127_6313292_7 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.0000000000000000000213 94.0
HFD3_k127_6313292_8 photosystem II stabilization K02237 - - 0.0000004604 56.0
HFD3_k127_6313292_9 RNA polymerase sigma factor K03088 - - 0.0003573 49.0
HFD3_k127_6329919_0 transposase activity K07493,K08178 - - 2.258e-209 660.0
HFD3_k127_6329919_1 - - - - 0.00000000000000007427 81.0
HFD3_k127_6338700_0 ABC transporter, transmembrane K11085 - - 1.891e-220 702.0
HFD3_k127_6338700_1 TIGRFAM drug resistance transporter, EmrB QacA subfamily K03446 - - 1.969e-201 640.0
HFD3_k127_6338700_10 Putative modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003374 284.0
HFD3_k127_6338700_11 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002987 240.0
HFD3_k127_6338700_12 heme binding K08259 - 3.4.24.75 0.000000000000000000000000000000000000000000000000000023 200.0
HFD3_k127_6338700_13 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000001664 148.0
HFD3_k127_6338700_14 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000002164 114.0
HFD3_k127_6338700_15 - - - - 0.000000000000000000000001397 110.0
HFD3_k127_6338700_16 Bacterial regulatory proteins, tetR family K13770 - - 0.000000000000000002609 93.0
HFD3_k127_6338700_17 Protein of unknown function (DUF3347) - - - 0.000000006667 63.0
HFD3_k127_6338700_2 metallopeptidase activity K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 507.0
HFD3_k127_6338700_3 Beta-Casp domain K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 501.0
HFD3_k127_6338700_4 beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 447.0
HFD3_k127_6338700_5 SMART PDZ DHR GLGF domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004417 417.0
HFD3_k127_6338700_6 Major Facilitator Superfamily K13021 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 336.0
HFD3_k127_6338700_7 Biotin-lipoyl like K03543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006552 327.0
HFD3_k127_6338700_8 outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 312.0
HFD3_k127_6338700_9 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 299.0
HFD3_k127_6360703_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1367.0
HFD3_k127_6360703_1 peptidoglycan glycosyltransferase activity K03588,K05364,K05837 GO:0002682,GO:0002684,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136 - 1.688e-300 955.0
HFD3_k127_6360703_10 histone H2A K63-linked ubiquitination K01768,K03220,K10914 - 4.6.1.1 0.0000000000000000000000000000000000000000000433 170.0
HFD3_k127_6360703_11 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000000005095 147.0
HFD3_k127_6360703_12 Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.000000000000000000000000000004183 126.0
HFD3_k127_6360703_13 histone H2A K63-linked ubiquitination K02283 - - 0.0000000000000000004033 97.0
HFD3_k127_6360703_14 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 GO:0003674,GO:0004857,GO:0005488,GO:0008150,GO:0008270,GO:0008657,GO:0010911,GO:0030234,GO:0032780,GO:0042030,GO:0043086,GO:0043167,GO:0043169,GO:0043462,GO:0044092,GO:0046872,GO:0046914,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0072586,GO:0098772,GO:2000371,GO:2000372 - 0.00000000000000009947 81.0
HFD3_k127_6360703_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003694 385.0
HFD3_k127_6360703_3 Belongs to the CinA family K03742 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006689 372.0
HFD3_k127_6360703_4 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006416 344.0
HFD3_k127_6360703_5 HlyD family secretion protein K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 342.0
HFD3_k127_6360703_6 PFAM NAD-dependent glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005563 336.0
HFD3_k127_6360703_7 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008002 304.0
HFD3_k127_6360703_8 Thioredoxin K03672 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000000008898 197.0
HFD3_k127_6360703_9 protein kinase activity - - - 0.000000000000000000000000000000000000000000005528 185.0
HFD3_k127_6365754_0 Ftsk_gamma K03466 - - 7.799e-203 656.0
HFD3_k127_6365754_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 1.944e-195 623.0
HFD3_k127_6365754_2 Bacitracin resistance protein BacA K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000916 236.0
HFD3_k127_6365754_3 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000002756 199.0
HFD3_k127_6365754_4 23S rRNA-intervening sequence protein - - - 0.000000000000000000000003938 106.0
HFD3_k127_6377289_0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989,K02428 - 2.7.7.56,3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008611 305.0
HFD3_k127_6377289_1 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.0000000000000000000000000000000000000000003529 165.0
HFD3_k127_6377289_2 multi-organism process K03195 - - 0.000000000000000000000000000000000002907 145.0
HFD3_k127_6377289_3 TIGRFAM RHS repeat-associated core domain - - - 0.000000000000000000008298 105.0
HFD3_k127_6377289_4 Sporulation and spore germination - - - 0.0000000000000000000104 101.0
HFD3_k127_6377289_5 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.00000000000000002144 96.0
HFD3_k127_6377289_8 - - - - 0.0002962 43.0
HFD3_k127_6377289_9 Transmembrane proteins 14C - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 - 0.0006108 48.0
HFD3_k127_6388281_0 PFAM ABC transporter transmembrane K06147 - - 3.947e-257 804.0
HFD3_k127_6388281_1 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000004985 241.0
HFD3_k127_6388281_2 Domain of unknown function (DUF4159) - - - 0.0000000000000000000000000000000000000001249 160.0
HFD3_k127_6400458_0 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001865 284.0
HFD3_k127_6400458_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000056 263.0
HFD3_k127_6400458_2 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000304 206.0
HFD3_k127_6400458_3 - - - - 0.0000000000000000000000000000000004549 146.0
HFD3_k127_6401755_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003564 558.0
HFD3_k127_6401755_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005206 353.0
HFD3_k127_6401755_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009498 333.0
HFD3_k127_6401755_3 Thymidine kinase K00857 - 2.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000004578 244.0
HFD3_k127_6414122_0 Putative glucoamylase - - - 0.0 2665.0
HFD3_k127_6414122_1 Glutamate synthase central domain K00265,K00284 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2119.0
HFD3_k127_6414122_10 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0006091,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0009314,GO:0009416,GO:0009628,GO:0009642,GO:0009644,GO:0009765,GO:0009892,GO:0009987,GO:0010109,GO:0010205,GO:0010206,GO:0010304,GO:0015979,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0019538,GO:0019684,GO:0030091,GO:0030163,GO:0031323,GO:0031324,GO:0042548,GO:0042623,GO:0043155,GO:0043170,GO:0043467,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0065007,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1905156 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009616 568.0
HFD3_k127_6414122_11 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005126 548.0
HFD3_k127_6414122_12 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 461.0
HFD3_k127_6414122_13 response regulator K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 455.0
HFD3_k127_6414122_14 Mediates influx of magnesium ions K03284,K16074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007069 443.0
HFD3_k127_6414122_15 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008481 411.0
HFD3_k127_6414122_16 shikimate 3-dehydrogenase (NADP+) activity K00800,K10669 GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19,2.7.1.160 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007351 399.0
HFD3_k127_6414122_17 Dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 394.0
HFD3_k127_6414122_18 Mn2 dependent serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 378.0
HFD3_k127_6414122_19 NADH flavin K10680 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 377.0
HFD3_k127_6414122_2 Spermine/spermidine synthase domain - - - 2.891e-270 855.0
HFD3_k127_6414122_20 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 357.0
HFD3_k127_6414122_21 Protein of unknown function (DUF1326) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007721 342.0
HFD3_k127_6414122_22 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003512 316.0
HFD3_k127_6414122_23 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004747 315.0
HFD3_k127_6414122_24 RNA polymerase, sigma-24 subunit, ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005619 310.0
HFD3_k127_6414122_25 COG1233 Phytoene dehydrogenase and related proteins K10254 - 4.2.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005542 309.0
HFD3_k127_6414122_26 PFAM peptidase M24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 298.0
HFD3_k127_6414122_27 Bacterioferritin (cytochrome b1) K03594 - 1.16.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004078 279.0
HFD3_k127_6414122_28 with different specificities (related to short-chain alcohol K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006741 291.0
HFD3_k127_6414122_29 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002571 281.0
HFD3_k127_6414122_3 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 4.588e-269 852.0
HFD3_k127_6414122_30 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006539 274.0
HFD3_k127_6414122_31 Cytochrome C biogenesis protein K06196,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000004603 263.0
HFD3_k127_6414122_32 dUTPase K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000001366 252.0
HFD3_k127_6414122_33 COG0583 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000419 252.0
HFD3_k127_6414122_34 sequence-specific DNA binding K01239,K02855,K07506,K18199 - 3.2.2.1,4.2.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000007265 246.0
HFD3_k127_6414122_35 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001675 246.0
HFD3_k127_6414122_36 3'(2'),5'-bisphosphate nucleotidase activity K01082 - 3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000005434 244.0
HFD3_k127_6414122_37 Transporter associated domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000001259 247.0
HFD3_k127_6414122_38 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000000000000008502 230.0
HFD3_k127_6414122_39 translation release factor activity - - - 0.00000000000000000000000000000000000000000000000000003506 202.0
HFD3_k127_6414122_4 Dehydrogenase K00114,K17760,K20936,K21676,K22473 - 1.1.2.8,1.1.2.9,1.1.5.5,1.1.9.1,1.17.2.2 2.835e-250 792.0
HFD3_k127_6414122_40 MFS_1 like family K08161 - - 0.00000000000000000000000000000000000000000000000000369 199.0
HFD3_k127_6414122_41 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000007782 191.0
HFD3_k127_6414122_42 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000001584 192.0
HFD3_k127_6414122_43 adenylylsulfate kinase activity K00860,K00955 - 2.7.1.25,2.7.7.4 0.0000000000000000000000000000000000000000000006076 171.0
HFD3_k127_6414122_44 pfam nudix K01515 - 3.6.1.13 0.000000000000000000000000000000000000000005065 162.0
HFD3_k127_6414122_45 CarD-like/TRCF domain K07736 - - 0.000000000000000000000000000000000000000005825 160.0
HFD3_k127_6414122_46 - - - - 0.0000000000000000000000000000000000000000825 158.0
HFD3_k127_6414122_47 - - - - 0.000000000000000000000000000000000000003018 152.0
HFD3_k127_6414122_48 bacterial (prokaryotic) histone like domain K03530 - - 0.000000000000000000000000000000000000003906 147.0
HFD3_k127_6414122_49 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000001207 137.0
HFD3_k127_6414122_5 Flavin containing amine oxidoreductase K00266 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 1.071e-231 724.0
HFD3_k127_6414122_50 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000000000000000000000000000000002047 136.0
HFD3_k127_6414122_51 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.0000000000000000000000000000000002373 138.0
HFD3_k127_6414122_52 Dienelactone hydrolase - - - 0.0000000000000000000000000000000009364 132.0
HFD3_k127_6414122_53 Phosphoribosyl transferase domain K07100 - - 0.00000000000000000000000000000001477 136.0
HFD3_k127_6414122_54 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000000000000000000000000000187 138.0
HFD3_k127_6414122_55 Pfam Response regulator receiver - - - 0.000000000000000000000000000001692 132.0
HFD3_k127_6414122_56 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.00000000000000000000000000002623 126.0
HFD3_k127_6414122_57 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000000000000000000008624 128.0
HFD3_k127_6414122_58 Ankyrin repeat - - - 0.0000000000000000000000000001646 132.0
HFD3_k127_6414122_59 Protoglobin - - - 0.0000000000000000000000000004819 128.0
HFD3_k127_6414122_6 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 2.442e-226 712.0
HFD3_k127_6414122_60 - - - - 0.000000000000000000000000003322 124.0
HFD3_k127_6414122_61 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase) K04757 - 2.7.11.1 0.000000000000000000000003655 108.0
HFD3_k127_6414122_62 - - - - 0.000000000000000000000007517 107.0
HFD3_k127_6414122_63 - - - - 0.0000000000000000000000132 112.0
HFD3_k127_6414122_64 Bacterial protein of unknown function (DUF899) - - - 0.00000000000000000007367 91.0
HFD3_k127_6414122_65 ribonuclease BN K07058 - - 0.000000000000000000506 98.0
HFD3_k127_6414122_66 - - - - 0.0000000000000000007101 92.0
HFD3_k127_6414122_67 Sigma-54 interaction domain - - - 0.00000000000000001368 86.0
HFD3_k127_6414122_68 hemerythrin HHE cation binding domain - - - 0.00000000000000004544 89.0
HFD3_k127_6414122_69 NapC/NirT cytochrome c family, N-terminal region K02569 - - 0.000000000000001459 86.0
HFD3_k127_6414122_7 DNA topological change K03168 - 5.99.1.2 5.49e-212 685.0
HFD3_k127_6414122_70 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.000000000000004626 85.0
HFD3_k127_6414122_71 Universal stress protein family - - - 0.00000000001048 76.0
HFD3_k127_6414122_72 SnoaL-like domain - - - 0.00000000004158 72.0
HFD3_k127_6414122_73 - - - - 0.00000001089 68.0
HFD3_k127_6414122_74 PFAM CHAD domain containing protein - - - 0.0000001022 62.0
HFD3_k127_6414122_75 Cytochrome c K00406,K08906 - - 0.0000007004 55.0
HFD3_k127_6414122_76 - - - - 0.000172 49.0
HFD3_k127_6414122_8 2-methylcitrate dehydratase activity - - - 5.913e-211 665.0
HFD3_k127_6414122_9 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 602.0
HFD3_k127_64184_0 ABC transporter K10441 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 540.0
HFD3_k127_64184_1 glucuronate isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003657 466.0
HFD3_k127_64184_2 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008434 413.0
HFD3_k127_64184_3 - - - - 0.0000000000000001113 85.0
HFD3_k127_64184_4 - K02172 - - 0.000002544 52.0
HFD3_k127_6429992_0 Multicopper oxidase - - - 3.368e-198 636.0
HFD3_k127_6429992_1 Peptidase dimerisation domain K13049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 505.0
HFD3_k127_6429992_2 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002901 473.0
HFD3_k127_6429992_3 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008754 463.0
HFD3_k127_6429992_4 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 308.0
HFD3_k127_6429992_5 haloacid dehalogenase-like hydrolase - - - 0.00000000000001396 81.0
HFD3_k127_6429992_6 MacB-like periplasmic core domain - - - 0.0000000000006545 75.0
HFD3_k127_6429992_7 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.000000006782 69.0
HFD3_k127_6508710_0 Pkd domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 593.0
HFD3_k127_6508710_1 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 533.0
HFD3_k127_6508710_2 Arylsulfotransferase (ASST) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009209 415.0
HFD3_k127_6508710_3 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000000000000000000000000000000005002 185.0
HFD3_k127_6508710_4 PKD domain containing protein K01337,K20276,K21449 - 3.4.21.50 0.000000000000000000000000222 124.0
HFD3_k127_6515349_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 6.221e-289 912.0
HFD3_k127_6515349_1 COG0644 Dehydrogenases (flavoproteins) - - - 1.163e-211 664.0
HFD3_k127_6515349_10 Psort location CytoplasmicMembrane, score K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 296.0
HFD3_k127_6515349_11 protein kinase related protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000537 296.0
HFD3_k127_6515349_12 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001401 274.0
HFD3_k127_6515349_13 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000246 211.0
HFD3_k127_6515349_14 PFAM Peptidase M22, glycoprotease K01409,K14742 - 2.3.1.234 0.000000000000000000000000000001382 130.0
HFD3_k127_6515349_15 Thioesterase superfamily K01075,K07107 - 3.1.2.23 0.000000000000000000000000002131 116.0
HFD3_k127_6515349_16 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.000000000000000000000004521 109.0
HFD3_k127_6515349_2 COG0635 Coproporphyrinogen III oxidase and related Fe-S - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 521.0
HFD3_k127_6515349_3 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 519.0
HFD3_k127_6515349_4 TonB dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 538.0
HFD3_k127_6515349_5 protein kinase related protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 492.0
HFD3_k127_6515349_6 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004631 422.0
HFD3_k127_6515349_7 Iron-containing alcohol dehydrogenase K00001,K13954 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005632 413.0
HFD3_k127_6515349_8 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 384.0
HFD3_k127_6515349_9 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 375.0
HFD3_k127_6517302_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168,K07479 GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.2 3.14e-291 915.0
HFD3_k127_6517302_1 DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003485 281.0
HFD3_k127_6517302_2 PFAM Mur ligase family, glutamate ligase domain K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000001105 248.0
HFD3_k127_6517302_3 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000003997 190.0
HFD3_k127_6517302_4 peptidase C26 K07010 - - 0.00000000000000000000000000000000000000000000000002546 188.0
HFD3_k127_6517302_5 Cytochrome C biogenesis protein transmembrane region - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000009167 165.0
HFD3_k127_6517302_6 Putative transposase - - - 0.0000000000000000001096 93.0
HFD3_k127_6517302_7 dipeptidyl-peptidase activity - - - 0.0000000000002513 81.0
HFD3_k127_6517302_8 - - - - 0.000000000004863 77.0
HFD3_k127_6540991_2 - - - - 0.00000001216 67.0
HFD3_k127_6596636_0 phosphopentomutase activity K01839 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008973,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 5.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000004454 269.0
HFD3_k127_6596636_1 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000000000000005407 207.0
HFD3_k127_6605332_0 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000000423 176.0
HFD3_k127_6605332_1 metallophosphoesterase K07098 - - 0.0000000000000000000000000000000000004553 152.0
HFD3_k127_6605332_2 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000002026 124.0
HFD3_k127_6605332_3 - - - - 0.00000000000000002668 95.0
HFD3_k127_6605332_4 Universal stress protein - - - 0.000001699 55.0
HFD3_k127_6608787_0 Thermolysin metallopeptidase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 532.0
HFD3_k127_6608787_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005508 389.0
HFD3_k127_6608787_2 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 307.0
HFD3_k127_6608787_4 Redoxin - - - 0.00000000000000000000001699 107.0
HFD3_k127_6608787_6 helix_turn_helix, arabinose operon control protein K07720 - - 0.00000000002461 70.0
HFD3_k127_6629938_0 membrane K07027,K14205 - 2.3.2.3 1.901e-247 790.0
HFD3_k127_6629938_1 ABC transporter K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 300.0
HFD3_k127_6629938_2 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000000000000000000427 229.0
HFD3_k127_6629938_3 Amidohydrolase family K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000314 238.0
HFD3_k127_6629938_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000006094 219.0
HFD3_k127_6629938_5 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000005673 131.0
HFD3_k127_6629938_6 Chaperone - - - 0.000006697 56.0
HFD3_k127_6629938_7 Prolyl oligopeptidase family K06889 - - 0.00002169 55.0
HFD3_k127_6632631_0 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007628 470.0
HFD3_k127_6632631_1 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 336.0
HFD3_k127_6632638_0 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003627 487.0
HFD3_k127_6632638_1 Type III restriction enzyme res subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 330.0
HFD3_k127_6632638_2 2OG-Fe(II) oxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 291.0
HFD3_k127_6632638_4 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000003166 136.0
HFD3_k127_6639449_0 Alpha amylase, catalytic domain K00690,K05343 - 2.4.1.7,3.2.1.1,5.4.99.16 1.368e-207 654.0
HFD3_k127_6639449_1 pfkB family carbohydrate kinase K00847 - 2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008815 332.0
HFD3_k127_66508_0 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 527.0
HFD3_k127_66508_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 308.0
HFD3_k127_66508_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005917 307.0
HFD3_k127_66508_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000001926 204.0
HFD3_k127_6656487_0 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009048 503.0
HFD3_k127_6656487_1 A domain in the BMP inhibitor chordin and in microbial proteins. - - - 0.00007675 52.0
HFD3_k127_66888_0 Group II intron maturase-specific domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 418.0
HFD3_k127_66888_1 Domain of unknown function (DUF5122) beta-propeller - - - 0.000000000000000000000000000000000000000003296 173.0
HFD3_k127_66888_2 - - - - 0.00000000000000272 81.0
HFD3_k127_66888_3 COG3540 Phosphodiesterase alkaline phosphatase D K01113 - 3.1.3.1 0.0004539 51.0
HFD3_k127_6689574_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05825 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002216 266.0
HFD3_k127_6689574_1 Putative restriction endonuclease - - - 0.0000000000000000000000000000008941 130.0
HFD3_k127_6689574_2 domain protein - - - 0.000000000000000000000000007031 126.0
HFD3_k127_6700155_0 Tannase and feruloyl esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 556.0
HFD3_k127_6700155_1 Transcriptional regulator K12146,K15836 GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001150,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0042802,GO:0043170,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 557.0
HFD3_k127_6700155_2 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006192 303.0
HFD3_k127_6700155_3 molybdenum ion binding K07140 - - 0.000000000000000000000000000000000000000000000000000000000000006822 224.0
HFD3_k127_6700155_4 Protein of unknown function (DUF1348) - - - 0.0000000000000000000000000000000000000000000000000000000004294 205.0
HFD3_k127_6700155_5 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000001026 205.0
HFD3_k127_6700155_6 ADP binding K10407 - - 0.0000000000000000000002078 109.0
HFD3_k127_6700155_7 Major Facilitator Superfamily - - - 0.0000000000000000000002983 102.0
HFD3_k127_6700155_8 glyoxalase III activity K00799 - 2.5.1.18 0.000000004475 63.0
HFD3_k127_6715354_0 amino acid - - - 0.0 1038.0
HFD3_k127_6715354_1 DNA topological change K03168 - 5.99.1.2 2.692e-248 792.0
HFD3_k127_6715354_10 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003707 334.0
HFD3_k127_6715354_11 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 350.0
HFD3_k127_6715354_12 dTDP biosynthetic process K00560,K00943,K01585 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.1.1.45,2.7.4.9,4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 314.0
HFD3_k127_6715354_13 Ankyrin repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005394 291.0
HFD3_k127_6715354_14 dTDP biosynthetic process K00943,K01585 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.9,4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000002346 267.0
HFD3_k127_6715354_15 Oxidoreductase molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002207 265.0
HFD3_k127_6715354_16 von Willebrand factor, type A K12511 - - 0.0000000000000000000000000000000000000000000000000000000000000006455 239.0
HFD3_k127_6715354_17 Transcriptional Regulator, AraC family - - - 0.00000000000000000000000000000000000000000000000000000004987 205.0
HFD3_k127_6715354_18 DNA-templated transcription, initiation K02405 - - 0.000000000000000000000000000000000000000000000000000001936 199.0
HFD3_k127_6715354_19 Maleate cis-trans isomerase - - - 0.00000000000000000000000000000000000000000000000705 183.0
HFD3_k127_6715354_2 transcription factor binding K02584,K12146,K12266,K15836,K21009 GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001150,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0042802,GO:0043170,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001141 - 1.508e-222 709.0
HFD3_k127_6715354_20 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain K00567 GO:0003674,GO:0003824,GO:0003908,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051409,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 2.1.1.63 0.000000000000000000000000000000000000000000001183 170.0
HFD3_k127_6715354_21 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000259 167.0
HFD3_k127_6715354_22 SnoaL-like domain - - - 0.000000000000000000000000000000000002347 149.0
HFD3_k127_6715354_23 acetyltransferase - - - 0.00000000000000000000000000000321 128.0
HFD3_k127_6715354_24 protein import - - - 0.000000000000000000000000002994 120.0
HFD3_k127_6715354_25 Domain of unknown function (DUF1992) - - - 0.000000000000000000000000009619 112.0
HFD3_k127_6715354_26 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000388 105.0
HFD3_k127_6715354_3 serine-type peptidase activity K01990,K08884,K12132,K18912 - 1.14.99.50,2.7.11.1 9.331e-221 715.0
HFD3_k127_6715354_4 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 1.185e-215 684.0
HFD3_k127_6715354_5 Creatinase/Prolidase N-terminal domain K08688 - 3.5.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008737 528.0
HFD3_k127_6715354_6 alpha-L-arabinofuranosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 539.0
HFD3_k127_6715354_7 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 430.0
HFD3_k127_6715354_8 Protein of unknown function (DUF1552) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003543 394.0
HFD3_k127_6715354_9 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006286 334.0
HFD3_k127_6777846_0 His Kinase A (phosphoacceptor) domain K02482 - 2.7.13.3 9.822e-262 819.0
HFD3_k127_6777846_1 Belongs to the DNA glycosylase MPG family K03652 GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000249 280.0
HFD3_k127_6777846_3 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000009798 163.0
HFD3_k127_6777846_4 Cytochrome c K03611 - - 0.0000000000000000000000000000000000000209 145.0
HFD3_k127_6777846_6 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.000000000000000004177 89.0
HFD3_k127_678797_0 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006297 627.0
HFD3_k127_678797_1 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004567 350.0
HFD3_k127_678797_3 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion K02564 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 3.5.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003725 279.0
HFD3_k127_678797_4 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000006366 229.0
HFD3_k127_678797_5 - - - - 0.0000000000000000000000000000000000000000000001207 179.0
HFD3_k127_678797_6 - - - - 0.0000000000000000000000007905 109.0
HFD3_k127_678797_7 Phospholipase/Carboxylesterase - - - 0.00000000000000000008724 101.0
HFD3_k127_678956_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 5.967e-264 837.0
HFD3_k127_678956_1 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 7.401e-224 703.0
HFD3_k127_678956_2 Belongs to the xylose isomerase family K01805 - 5.3.1.5 3.017e-197 621.0
HFD3_k127_678956_3 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 424.0
HFD3_k127_678956_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 349.0
HFD3_k127_678956_5 2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase K01625 - 4.1.2.14,4.1.3.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 284.0
HFD3_k127_678956_6 domain protein K14194 - - 0.000000000000000000000000000000000000000000000009106 192.0
HFD3_k127_678956_7 Belongs to the ClpA ClpB family K03696 - - 0.0000000000000000000000000000000000005251 148.0
HFD3_k127_678956_8 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000008026 119.0
HFD3_k127_6827542_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 1.642e-213 679.0
HFD3_k127_6827542_1 PFAM Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000811 516.0
HFD3_k127_6827542_12 YtxH-like protein - - - 0.0000000000000001011 89.0
HFD3_k127_6827542_2 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 463.0
HFD3_k127_6827542_3 Associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 393.0
HFD3_k127_6827542_4 Von Willebrand factor type A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 312.0
HFD3_k127_6827542_5 - K01286 - 3.4.16.4 0.00000000000000000000000000000000000000000000000001025 206.0
HFD3_k127_6827542_6 Penicillinase repressor - - - 0.0000000000000000000000000000000000000000000000002757 178.0
HFD3_k127_6827542_7 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000002469 184.0
HFD3_k127_6827542_8 transcriptional regulator PadR family - - - 0.00000000000000000000000000000000000009066 144.0
HFD3_k127_6827542_9 PFAM ATP-dependent protease La (LON) domain K01338 - 3.4.21.53 0.0000000000000000000000000000003183 131.0
HFD3_k127_6827685_0 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 3.847e-230 729.0
HFD3_k127_6827685_1 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 1.332e-208 667.0
HFD3_k127_6827685_10 Belongs to the GSP D family K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 392.0
HFD3_k127_6827685_11 involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007194 342.0
HFD3_k127_6827685_12 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004616 331.0
HFD3_k127_6827685_13 Bacterial sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003147 327.0
HFD3_k127_6827685_14 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000513 325.0
HFD3_k127_6827685_15 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 316.0
HFD3_k127_6827685_16 monooxygenase, FAD-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005861 319.0
HFD3_k127_6827685_17 Peptidylprolyl isomerase K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000001396 286.0
HFD3_k127_6827685_18 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001036 284.0
HFD3_k127_6827685_19 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000006618 239.0
HFD3_k127_6827685_2 PFAM RNA-binding protein AU-1 Ribonuclease E G K08301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 585.0
HFD3_k127_6827685_20 PFAM CBS domain - - - 0.0000000000000000000000000000000000000000000000000000000000007104 226.0
HFD3_k127_6827685_21 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000003064 210.0
HFD3_k127_6827685_22 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000000000003758 189.0
HFD3_k127_6827685_23 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000000000000000000000000000008499 175.0
HFD3_k127_6827685_24 Rod shape-determining protein MreC K03570 - - 0.00000000000000000000000000000000002467 146.0
HFD3_k127_6827685_25 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000000000000002402 134.0
HFD3_k127_6827685_26 Protein of unknown function (DUF3175) - - - 0.00000000000000000000000000000001071 128.0
HFD3_k127_6827685_27 cheY-homologous receiver domain - - - 0.0000000000000000000000000003838 119.0
HFD3_k127_6827685_28 BON domain - - - 0.000000000000000000000000006225 118.0
HFD3_k127_6827685_29 - - - - 0.0000000000000000000004992 105.0
HFD3_k127_6827685_3 cell shape determining protein MreB K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 546.0
HFD3_k127_6827685_30 shape-determining protein MreD K03571 - - 0.00000000000000001933 91.0
HFD3_k127_6827685_31 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K01489,K07042 - 3.5.4.5 0.00000000000000005435 86.0
HFD3_k127_6827685_32 - - - - 0.0000000000000001538 80.0
HFD3_k127_6827685_33 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000000006732 80.0
HFD3_k127_6827685_34 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000003212 66.0
HFD3_k127_6827685_35 FIC domain containing - GO:0000166,GO:0003008,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005737,GO:0005783,GO:0005789,GO:0005886,GO:0006464,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006836,GO:0006950,GO:0006952,GO:0007600,GO:0007601,GO:0007610,GO:0007632,GO:0008081,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009416,GO:0009581,GO:0009582,GO:0009583,GO:0009584,GO:0009605,GO:0009607,GO:0009617,GO:0009628,GO:0009966,GO:0009987,GO:0010646,GO:0012505,GO:0015696,GO:0016020,GO:0016021,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0017076,GO:0018117,GO:0018175,GO:0019538,GO:0023051,GO:0030176,GO:0030544,GO:0030554,GO:0031072,GO:0031224,GO:0031227,GO:0031967,GO:0031975,GO:0031984,GO:0032501,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034260,GO:0034976,GO:0035639,GO:0036094,GO:0036211,GO:0042175,GO:0042578,GO:0042742,GO:0042802,GO:0042803,GO:0043086,GO:0043087,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044092,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0044601,GO:0044602,GO:0044603,GO:0045117,GO:0046983,GO:0048519,GO:0048583,GO:0050789,GO:0050790,GO:0050794,GO:0050829,GO:0050877,GO:0050896,GO:0050906,GO:0050908,GO:0050953,GO:0050962,GO:0051087,GO:0051179,GO:0051234,GO:0051336,GO:0051346,GO:0051606,GO:0051608,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0065009,GO:0070566,GO:0070733,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0080134,GO:0080135,GO:0097159,GO:0097367,GO:0098542,GO:0098827,GO:0140096,GO:1900101,GO:1901265,GO:1901363,GO:1901564,GO:1903894,GO:1905897 - 0.000000005312 65.0
HFD3_k127_6827685_36 Rubrerythrin K03594 - 1.16.3.1 0.0003623 51.0
HFD3_k127_6827685_4 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000612 501.0
HFD3_k127_6827685_5 phosphorelay signal transduction system K07712,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005206 474.0
HFD3_k127_6827685_6 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002949 460.0
HFD3_k127_6827685_7 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 436.0
HFD3_k127_6827685_8 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005829 414.0
HFD3_k127_6827685_9 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 402.0
HFD3_k127_6831648_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004977 607.0
HFD3_k127_6831648_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006982 475.0
HFD3_k127_6831648_2 protein catabolic process K03420,K13525,K17681 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 399.0
HFD3_k127_6831648_3 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 367.0
HFD3_k127_6831648_4 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006767 388.0
HFD3_k127_6831648_5 NAD(P)H-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003145 259.0
HFD3_k127_6831648_6 helix_turn_helix, arabinose operon control protein K07506 - - 0.000000000000000000000000000000000000000000000000000000000008403 218.0
HFD3_k127_6831648_7 Tetratricopeptide repeat - - - 0.0000000000000000003396 95.0
HFD3_k127_6844919_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 541.0
HFD3_k127_6844919_1 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002933 418.0
HFD3_k127_6844919_10 - - - - 0.00002082 56.0
HFD3_k127_6844919_2 HupE / UreJ protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004339 276.0
HFD3_k127_6844919_3 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000000000000000000000000000001551 210.0
HFD3_k127_6844919_4 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000000000000000008941 184.0
HFD3_k127_6844919_5 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000002169 136.0
HFD3_k127_6844919_6 RNA polymerase sigma factor K03088 - - 0.0000000000000000000000000003955 124.0
HFD3_k127_6844919_7 domain protein K13735,K18491,K20276 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000003794 70.0
HFD3_k127_6844919_8 - - - - 0.0000006745 57.0
HFD3_k127_6844919_9 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00001291 57.0
HFD3_k127_689547_0 TIGRFAM carbamoyl-phosphate synthase, large subunit K01955 - 6.3.5.5 0.0 1461.0
HFD3_k127_689547_1 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 474.0
HFD3_k127_689547_10 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000003453 64.0
HFD3_k127_689547_11 Pfam:N_methyl_2 - - - 0.0000002529 61.0
HFD3_k127_689547_12 Phage tail tube, TTP, lambda-like - - - 0.00005538 57.0
HFD3_k127_689547_13 Prokaryotic N-terminal methylation motif K08084 - - 0.00007607 53.0
HFD3_k127_689547_2 TIGRFAM Carbamoyl-phosphate synthase, small subunit K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 464.0
HFD3_k127_689547_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 400.0
HFD3_k127_689547_4 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family K03317 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 334.0
HFD3_k127_689547_5 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000001526 223.0
HFD3_k127_689547_6 Ribosomal protein L11 methyltransferase K02687 - - 0.00000000000000000000000000000000000000000000021 178.0
HFD3_k127_689547_7 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000002223 142.0
HFD3_k127_689547_8 HsdM N-terminal domain K03427 - 2.1.1.72 0.000000000000000000000000000000009924 133.0
HFD3_k127_689547_9 - - - - 0.0000000000000000008076 96.0
HFD3_k127_691507_0 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004808 578.0
HFD3_k127_691507_1 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 496.0
HFD3_k127_691507_10 ABC-2 family transporter protein K01992,K07052,K09696 - - 0.000000000000000000000000000000000000006823 166.0
HFD3_k127_691507_11 COG1668 ABC-type Na efflux pump, permease component K01992,K09696 - - 0.0000000000000000000000000000000002305 147.0
HFD3_k127_691507_12 PFAM Class I peptide chain release factor K15034 - - 0.000000000000000000000000000000007578 132.0
HFD3_k127_691507_13 ThiS family K03636 - - 0.00000000000000000000005162 101.0
HFD3_k127_691507_2 PFAM Patatin-like phospholipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005255 436.0
HFD3_k127_691507_3 protease with the C-terminal PDZ domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009487 376.0
HFD3_k127_691507_4 asparaginase activity K01424 - 3.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 333.0
HFD3_k127_691507_5 ABC transporter K01990,K09697 - 3.6.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000004563 263.0
HFD3_k127_691507_6 PFAM LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000009262 221.0
HFD3_k127_691507_7 TPM domain K06872 - - 0.00000000000000000000000000000000000000000000000000000000001066 216.0
HFD3_k127_691507_8 Membrane K08988 - - 0.0000000000000000000000000000000000000000001019 169.0
HFD3_k127_691507_9 PFAM Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000000000000000001042 161.0
HFD3_k127_6921785_0 PFAM Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1577.0
HFD3_k127_6921785_1 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000003716 226.0
HFD3_k127_6944898_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 450.0
HFD3_k127_6944898_1 Bacterial protein of unknown function (DUF839) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 332.0
HFD3_k127_6944898_2 Transcriptional regulatory protein, C terminal K02483,K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002508 255.0
HFD3_k127_6944898_3 PFAM Cache K08738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004544 260.0
HFD3_k127_6944898_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000004049 212.0
HFD3_k127_6944898_5 hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000001477 164.0
HFD3_k127_6944898_6 Single Cache domain 2 K07647 - 2.7.13.3 0.0000000000000000000000000000000000000000006577 178.0
HFD3_k127_6944898_7 Trypsin-like peptidase domain - - - 0.00000000000000000000000000000000000005746 152.0
HFD3_k127_6944898_8 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - 0.0000000000000000000000000002346 119.0
HFD3_k127_6988852_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 312.0
HFD3_k127_6988852_1 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001393 266.0
HFD3_k127_6988852_2 Protein of unknown function (DUF2400) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001152 251.0
HFD3_k127_6988852_3 HlyD family secretion protein K01993 - - 0.000000000000000000000000000000000000000000000000000000000000004561 232.0
HFD3_k127_6988852_4 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000001334 187.0
HFD3_k127_6988852_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000003136 178.0
HFD3_k127_6988852_6 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000005538 145.0
HFD3_k127_6989722_0 PFAM NAD-dependent epimerase dehydratase - - - 1.866e-197 626.0
HFD3_k127_6989722_1 DNA photolyase K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 559.0
HFD3_k127_6989722_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000002018 102.0
HFD3_k127_6989722_3 Lipocalin / cytosolic fatty-acid binding protein family K03098 - - 0.000000007295 58.0
HFD3_k127_699632_0 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 369.0
HFD3_k127_699632_1 ATP:ADP antiporter activity K01932,K03301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000714 372.0
HFD3_k127_699632_2 ATP ADP translocase K03301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000888 355.0
HFD3_k127_699632_3 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000002531 188.0
HFD3_k127_699632_5 Surface antigen - - - 0.0000000000000002197 92.0
HFD3_k127_6998508_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 417.0
HFD3_k127_6998508_1 Required for morphogenesis under gluconeogenic growth conditions - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 321.0
HFD3_k127_6998508_10 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 - - 0.00000005122 56.0
HFD3_k127_6998508_11 - - - - 0.00002578 47.0
HFD3_k127_6998508_2 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 320.0
HFD3_k127_6998508_3 Proline dehydrogenase K00318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000042 297.0
HFD3_k127_6998508_4 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000002736 251.0
HFD3_k127_6998508_5 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000001535 166.0
HFD3_k127_6998508_6 PFAM peptidase S13 D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.0000000000000000000000000000000006468 145.0
HFD3_k127_6998508_7 Smr domain - - - 0.000000000000000000000001714 104.0
HFD3_k127_6998508_8 protein conserved in bacteria - - - 0.0000000000000000208 89.0
HFD3_k127_6998508_9 Tetratricopeptide repeat - - - 0.000000000000002332 85.0
HFD3_k127_6999333_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1101.0
HFD3_k127_6999333_1 Spermine/spermidine synthase domain - - - 8.728e-254 807.0
HFD3_k127_6999333_10 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000004779 126.0
HFD3_k127_6999333_11 enzyme binding K00567,K07443 - 2.1.1.63 0.000000000000000000000000008027 114.0
HFD3_k127_6999333_12 PFAM peptidase M28 - - - 0.00000000000000000000002687 113.0
HFD3_k127_6999333_13 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.000000000009296 70.0
HFD3_k127_6999333_14 PFAM Magnesium chelatase, ChlI subunit K07391 - - 0.00001286 48.0
HFD3_k127_6999333_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.614e-228 716.0
HFD3_k127_6999333_3 PFAM amidinotransferase K01482 - 3.5.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001075 281.0
HFD3_k127_6999333_4 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000006035 179.0
HFD3_k127_6999333_5 TIGRFAM clan AA aspartic protease, AF_0612 family - - - 0.00000000000000000000000000000000000000000007324 162.0
HFD3_k127_6999333_6 ORF6N domain - - - 0.0000000000000000000000000000000000000000001883 166.0
HFD3_k127_6999333_7 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000002658 163.0
HFD3_k127_6999333_8 RNA-DNA hybrid ribonuclease activity - - - 0.00000000000000000000000000000007745 132.0
HFD3_k127_7004221_0 PFAM ABC transporter - - - 3.053e-267 832.0
HFD3_k127_7004221_1 ABC transporter K15738 - - 1.044e-249 783.0
HFD3_k127_7004221_10 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 359.0
HFD3_k127_7004221_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005615 329.0
HFD3_k127_7004221_12 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 320.0
HFD3_k127_7004221_13 Haem-degrading - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003495 310.0
HFD3_k127_7004221_14 peptidylprolyl isomerase, FKBP-type K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000004352 253.0
HFD3_k127_7004221_15 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001464 266.0
HFD3_k127_7004221_16 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002989 254.0
HFD3_k127_7004221_17 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000001338 244.0
HFD3_k127_7004221_18 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000002292 237.0
HFD3_k127_7004221_19 - - - - 0.000000000000000000000000000000000000000000000000000000000000000009013 247.0
HFD3_k127_7004221_2 Belongs to the peptidase M16 family K07263 - - 5.149e-247 795.0
HFD3_k127_7004221_20 protocatechuate 3,4-dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000001571 234.0
HFD3_k127_7004221_21 Putative RNA methylase family UPF0020 K07444,K12297 - 2.1.1.173,2.1.1.264 0.00000000000000000000000000000000000000000000000000000000000002146 231.0
HFD3_k127_7004221_22 methyltransferase K00590,K07319 - 2.1.1.113,2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000003392 218.0
HFD3_k127_7004221_23 response to abiotic stimulus K06867 - - 0.000000000000000000000000000000000000000000000000000000001132 209.0
HFD3_k127_7004221_24 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000003565 194.0
HFD3_k127_7004221_25 PFAM FAD binding domain K11472 - - 0.000000000000000000000000000000000000000001451 171.0
HFD3_k127_7004221_26 - - - - 0.000000000000000000000000000000000000000006759 167.0
HFD3_k127_7004221_27 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000001776 154.0
HFD3_k127_7004221_28 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000003394 149.0
HFD3_k127_7004221_29 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000000000000003893 149.0
HFD3_k127_7004221_3 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003906 569.0
HFD3_k127_7004221_30 Pfam Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000001076 160.0
HFD3_k127_7004221_31 RNA recognition motif - - - 0.00000000000000000000000000001575 120.0
HFD3_k127_7004221_32 - - - - 0.00000000000000000000000000001715 128.0
HFD3_k127_7004221_33 - - - - 0.000000000000000000000000002748 116.0
HFD3_k127_7004221_34 - - - - 0.000000000000000000523 94.0
HFD3_k127_7004221_35 - - - - 0.00000000000000002118 87.0
HFD3_k127_7004221_36 cytochrome complex assembly K02200,K04018 - - 0.0000000000000001758 87.0
HFD3_k127_7004221_4 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003127 519.0
HFD3_k127_7004221_5 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005093 518.0
HFD3_k127_7004221_6 O-methyltransferase activity - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 495.0
HFD3_k127_7004221_7 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008533 421.0
HFD3_k127_7004221_8 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005064 419.0
HFD3_k127_7004221_9 4Fe-4S dicluster domain K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008552 379.0
HFD3_k127_7008903_0 alpha-L-arabinofuranosidase domain protein K01209 - 3.2.1.55 2.873e-258 806.0
HFD3_k127_7008903_1 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 545.0
HFD3_k127_7008903_10 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000000000000000201 177.0
HFD3_k127_7008903_11 - - - - 0.0000000000000000000000000000000000003654 153.0
HFD3_k127_7008903_12 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.0000000000000000000000000000000000007143 152.0
HFD3_k127_7008903_14 - - - - 0.0000000000000000000000000001474 119.0
HFD3_k127_7008903_15 - - - - 0.00000000000000000000000004498 115.0
HFD3_k127_7008903_17 - - - - 0.0000000000000000002766 100.0
HFD3_k127_7008903_18 - - - - 0.000000000005078 72.0
HFD3_k127_7008903_19 - - - - 0.0000000002976 68.0
HFD3_k127_7008903_2 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005868 507.0
HFD3_k127_7008903_3 Serine hydrolase involved in the detoxification of formaldehyde - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 384.0
HFD3_k127_7008903_4 COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004446 315.0
HFD3_k127_7008903_5 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 293.0
HFD3_k127_7008903_6 - - - - 0.0000000000000000000000000000000000000000000000000000008255 203.0
HFD3_k127_7008903_7 carboxylic ester hydrolase activity K03929 - - 0.000000000000000000000000000000000000000000000000000001165 199.0
HFD3_k127_7008903_8 FCD - - - 0.0000000000000000000000000000000000000000000000000002576 194.0
HFD3_k127_7008903_9 Zn-dependent hydrolases of the beta-lactamase fold K17837 - 3.5.2.6 0.000000000000000000000000000000000000000000004706 177.0
HFD3_k127_7014800_0 Hsp70 protein K04043,K04044 - - 7.929e-272 841.0
HFD3_k127_7014800_1 TIGRFAM penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 5.145e-195 631.0
HFD3_k127_7014800_2 Iron-sulphur cluster assembly - - - 0.000000000000000000000000000000000005926 138.0
HFD3_k127_7034488_0 MmgE/PrpD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 564.0
HFD3_k127_7034488_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 454.0
HFD3_k127_7034488_10 - - - - 0.000000000005866 69.0
HFD3_k127_7034488_11 Metallo-beta-lactamase superfamily - - - 0.000007581 49.0
HFD3_k127_7034488_2 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 379.0
HFD3_k127_7034488_3 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 357.0
HFD3_k127_7034488_4 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 348.0
HFD3_k127_7034488_5 abc transporter K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 344.0
HFD3_k127_7034488_6 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 340.0
HFD3_k127_7034488_7 gamma-carboxymuconolactone decarboxylase subunit K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000000000000000000004718 210.0
HFD3_k127_7034488_8 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.0000000000000000000000000000000000000002843 153.0
HFD3_k127_7034488_9 2OG-Fe(II) oxygenase superfamily - - - 0.000000000001344 69.0
HFD3_k127_7035071_0 Serine hydrolase involved in the detoxification of formaldehyde - - - 5.674e-243 767.0
HFD3_k127_7035071_1 ABC transporter K10441 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006132 477.0
HFD3_k127_7035071_10 PFAM Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000007832 229.0
HFD3_k127_7035071_11 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000000000000000000000000004845 223.0
HFD3_k127_7035071_12 Phospholipase - - - 0.00000000000000000000000000000000000000000000000000001032 198.0
HFD3_k127_7035071_13 - - - - 0.00000000000000000000000000000000000000000000002192 184.0
HFD3_k127_7035071_14 Peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000000008363 136.0
HFD3_k127_7035071_15 DoxX - - - 0.000000000000000000000000000000001246 133.0
HFD3_k127_7035071_16 DNA alkylation repair enzyme - - - 0.00000000000000000000000000000000417 135.0
HFD3_k127_7035071_17 - - - - 0.00000000000000000000000000000000755 134.0
HFD3_k127_7035071_19 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00003791 57.0
HFD3_k127_7035071_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 389.0
HFD3_k127_7035071_3 Carbohydrate ABC transporter substrate-binding protein, CUT1 family K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 385.0
HFD3_k127_7035071_4 ABC-type sugar transport system periplasmic component K10439 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 378.0
HFD3_k127_7035071_5 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008717 369.0
HFD3_k127_7035071_6 Belongs to the ABC transporter superfamily K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003907 320.0
HFD3_k127_7035071_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009015 283.0
HFD3_k127_7035071_8 PFAM Binding-protein-dependent transport system inner membrane component K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007478 276.0
HFD3_k127_7035071_9 Branched-chain amino acid transport system / permease component K10440 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000006008 261.0
HFD3_k127_703983_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 0.0 1326.0
HFD3_k127_703983_1 PLD-like domain K06131 - - 3.348e-221 695.0
HFD3_k127_703983_2 Major facilitator superfamily K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 562.0
HFD3_k127_703983_3 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 570.0
HFD3_k127_703983_4 GMC oxidoreductase K06151 - 1.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 446.0
HFD3_k127_703983_5 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001306 284.0
HFD3_k127_703983_6 response regulator K07685 - - 0.0000000000000000000000000000000000003722 150.0
HFD3_k127_703983_7 - - - - 0.0000000000000000000000000000002517 130.0
HFD3_k127_703983_8 Gluconate 2-dehydrogenase subunit 3 K06152 - 1.1.99.3 0.00000000000000000000005777 108.0
HFD3_k127_7114327_0 metallocarboxypeptidase activity K14054 - - 0.0 1061.0
HFD3_k127_7114327_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004288 579.0
HFD3_k127_7114327_10 Protein of unknown function (DUF721) - - - 0.0008077 46.0
HFD3_k127_7114327_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005595 579.0
HFD3_k127_7114327_3 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 535.0
HFD3_k127_7114327_4 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 503.0
HFD3_k127_7114327_5 PFAM ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000001191 233.0
HFD3_k127_7114327_6 Outer membrane lipoprotein-sorting protein - - - 0.00000000000000000000000000000000000000000002587 171.0
HFD3_k127_7114327_7 Sh3 type 3 domain protein - - - 0.00000000000000006296 94.0
HFD3_k127_7114327_8 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000009522 69.0
HFD3_k127_7114327_9 Outer membrane protein (OmpH-like) K06142 - - 0.0000000009745 69.0
HFD3_k127_7134746_0 TonB-dependent receptor - - - 0.0 1516.0
HFD3_k127_7134746_1 PQQ-like domain K00114 - 1.1.2.8 2.815e-254 793.0
HFD3_k127_7134746_10 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009457 456.0
HFD3_k127_7134746_11 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 411.0
HFD3_k127_7134746_12 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 319.0
HFD3_k127_7134746_13 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K01142,K10773 GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006289,GO:0006296,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033683,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000001251 269.0
HFD3_k127_7134746_15 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002232 245.0
HFD3_k127_7134746_16 hydroperoxide reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003759 243.0
HFD3_k127_7134746_17 response to abiotic stimulus - - - 0.00000000000000000000000000000000000000000000000000000000000000000001234 258.0
HFD3_k127_7134746_18 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000004913 236.0
HFD3_k127_7134746_19 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000002841 219.0
HFD3_k127_7134746_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 5.049e-250 781.0
HFD3_k127_7134746_20 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000000000000000001846 204.0
HFD3_k127_7134746_21 rRNA (uridine-N3-)-methyltransferase activity K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000001085 186.0
HFD3_k127_7134746_22 Participates in transcription elongation, termination and antitermination K02601,K05785 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000004095 146.0
HFD3_k127_7134746_23 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000002803 126.0
HFD3_k127_7134746_24 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.000000000000000000000000000005724 125.0
HFD3_k127_7134746_25 FecR protein - - - 0.00000000000000000000000007088 123.0
HFD3_k127_7134746_26 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000004183 113.0
HFD3_k127_7134746_27 MacB-like periplasmic core domain - - - 0.000000000001762 70.0
HFD3_k127_7134746_28 - - - - 0.0002532 48.0
HFD3_k127_7134746_3 Aminomethyltransferase folate-binding domain K15066 - 2.1.1.341 1.104e-206 653.0
HFD3_k127_7134746_4 PFAM glycine cleavage T protein (aminomethyl transferase) - - - 4.663e-199 629.0
HFD3_k127_7134746_5 TIGRFAM SagB-type dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002865 618.0
HFD3_k127_7134746_6 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006218 599.0
HFD3_k127_7134746_7 Flavin-binding monooxygenase-like K03379,K21730 - 1.14.13.160,1.14.13.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 579.0
HFD3_k127_7134746_8 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000029 484.0
HFD3_k127_7134746_9 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 480.0
HFD3_k127_7184631_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 2.018e-222 708.0
HFD3_k127_7222412_0 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 494.0
HFD3_k127_7222412_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005884 334.0
HFD3_k127_7222412_2 helix_turn_helix, arabinose operon control protein - - - 0.000000000000007241 79.0
HFD3_k127_7258607_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 555.0
HFD3_k127_7258607_1 Permease, YjgP YjgQ - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 524.0
HFD3_k127_7258607_2 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 378.0
HFD3_k127_7258607_3 recombinase XerD K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 311.0
HFD3_k127_7258607_4 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000003219 206.0
HFD3_k127_7282914_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005285 571.0
HFD3_k127_7282914_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K20974 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 483.0
HFD3_k127_7282914_2 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 338.0
HFD3_k127_7282914_3 n-acetylmuramoyl-L-alanine amidase K01448 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008745,GO:0016787,GO:0016810,GO:0016811,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0061783 3.5.1.28 0.0002135 54.0
HFD3_k127_7290783_0 PFAM Extradiol ring-cleavage dioxygenase class III protein subunit B K04099 - 1.13.11.57 4.852e-197 622.0
HFD3_k127_7290783_1 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 383.0
HFD3_k127_7290783_2 serine-type peptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 316.0
HFD3_k127_7290783_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002964 251.0
HFD3_k127_7290783_4 - - - - 0.0000000000000000000000000000000000000000000000001042 187.0
HFD3_k127_7290783_5 PepSY-associated TM region - - - 0.00000000000000000000000000000000000000000000465 181.0
HFD3_k127_7290783_6 - - - - 0.00000000000000000000000000003791 123.0
HFD3_k127_7290783_7 - - - - 0.0000000000000000000000002098 118.0
HFD3_k127_7290783_8 - - - - 0.000000000000000003409 90.0
HFD3_k127_7327430_0 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004855 541.0
HFD3_k127_7327430_1 Cyclic nucleotide-monophosphate binding domain K10914 - - 0.0000000000000000000000000000000000000000000000000000004742 201.0
HFD3_k127_7327430_2 AI-2E family transporter - - - 0.0000000000000000000000006559 112.0
HFD3_k127_732783_0 Aldehyde dehydrogenase family K13877 - 1.2.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003431 558.0
HFD3_k127_732783_1 Belongs to the DapA family K01714,K13876 - 4.2.1.43,4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 501.0
HFD3_k127_732783_2 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 383.0
HFD3_k127_732783_3 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000791 266.0
HFD3_k127_732783_4 - - - - 0.00000000000000000000000000000000000000000000000000000000003517 218.0
HFD3_k127_732783_5 involved in chromosome partitioning K03496 - - 0.000000000000000000000000000000000000000000000000005709 197.0
HFD3_k127_732783_6 - - - - 0.0000000000000000000000005927 118.0
HFD3_k127_732783_7 - - - - 0.00000000000000000000001333 107.0
HFD3_k127_732783_8 - - - - 0.000000000000000000001936 100.0
HFD3_k127_732783_9 - - - - 0.000000000000001078 89.0
HFD3_k127_7327928_0 DNA topological change K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 600.0
HFD3_k127_7327928_1 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 467.0
HFD3_k127_7327928_10 - - - - 0.0000000000000000000000000000353 128.0
HFD3_k127_7327928_11 - - - - 0.0000000000000000000000001923 118.0
HFD3_k127_7327928_12 - - - - 0.00000000000000000000007507 102.0
HFD3_k127_7327928_13 - - - - 0.0000000000000000000007369 100.0
HFD3_k127_7327928_14 - - - - 0.0000000000000000009376 98.0
HFD3_k127_7327928_16 - - - - 0.0000005304 61.0
HFD3_k127_7327928_2 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 326.0
HFD3_k127_7327928_3 dioxygenase K15777 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0046566,GO:0051213,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001702 267.0
HFD3_k127_7327928_4 PFAM response regulator receiver K07665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002034 259.0
HFD3_k127_7327928_5 Sensor histidine kinase, HAMP domain-containing K07644 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000007695 256.0
HFD3_k127_7327928_6 - - - - 0.0000000000000000000000000000000000000000000000000000008787 203.0
HFD3_k127_7327928_7 Ankyrin repeat - - - 0.0000000000000000000000000000000000000000000000003755 198.0
HFD3_k127_7327928_8 PFAM phospholipase Carboxylesterase - - - 0.0000000000000000000000000000000000000000237 161.0
HFD3_k127_7327928_9 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000002076 130.0
HFD3_k127_7368244_0 ABC transporter, transmembrane K18890 - - 2.362e-212 674.0
HFD3_k127_7368244_1 ABC transporter, transmembrane K18889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 548.0
HFD3_k127_7368244_2 MOFRL family K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000485 426.0
HFD3_k127_7368244_3 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005922 309.0
HFD3_k127_7368244_4 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000005301 182.0
HFD3_k127_7368244_5 - - - - 0.000000000000000000000000000000000000000000000146 177.0
HFD3_k127_7368244_6 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000001719 155.0
HFD3_k127_7368244_7 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000009472 135.0
HFD3_k127_7368244_8 TPR repeat - - - 0.000007716 56.0
HFD3_k127_737117_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1202.0
HFD3_k127_737117_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000504 299.0
HFD3_k127_737117_2 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001024 263.0
HFD3_k127_737117_3 Electron transfer flavoprotein domain K03521 - - 0.000000000000000000000000000000000000000000000000000001473 200.0
HFD3_k127_737117_4 Helix-turn-helix domain - - - 0.000000000000000000000000000000000008166 145.0
HFD3_k127_737117_5 chaperone-mediated protein folding - - - 0.0000000000000000001198 99.0
HFD3_k127_737117_6 - - - - 0.000005222 57.0
HFD3_k127_737117_7 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0009976 49.0
HFD3_k127_7374210_0 Bacterial protein of unknown function (DUF853) K06915 - - 1.022e-216 682.0
HFD3_k127_7374210_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 2.417e-194 624.0
HFD3_k127_7374210_2 Ammonium Transporter Family K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 598.0
HFD3_k127_7374210_3 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 537.0
HFD3_k127_7374210_4 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008189 500.0
HFD3_k127_7374210_5 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008591 298.0
HFD3_k127_7374210_6 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001043 254.0
HFD3_k127_7374210_7 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000001844 237.0
HFD3_k127_7374210_8 efflux transmembrane transporter activity - - - 0.0000000003842 71.0
HFD3_k127_7398892_0 SPFH domain-Band 7 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002951 512.0
HFD3_k127_7398892_1 Tannase and feruloyl esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 477.0
HFD3_k127_7398892_2 tRNA wobble cytosine modification - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005342 449.0
HFD3_k127_7405018_0 Carboxypeptidase regulatory-like domain - - - 1.801e-229 755.0
HFD3_k127_7406164_0 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 307.0
HFD3_k127_7406164_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000001906 213.0
HFD3_k127_7406164_2 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000000000000000006423 204.0
HFD3_k127_7406164_3 AntiSigma factor - - - 0.00000000000000000000000000000000000000003054 166.0
HFD3_k127_7406164_4 Transmembrane anti-sigma factor - - - 0.000000000000000005309 89.0
HFD3_k127_7406252_0 Major facilitator superfamily K08191 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000589 619.0
HFD3_k127_7406252_1 carboxylic acid catabolic process K18334 - 4.2.1.68 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003713 613.0
HFD3_k127_7406252_2 PFAM transposase IS4 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005971 417.0
HFD3_k127_7406252_3 response regulator - - - 0.0000000000000000000001107 110.0
HFD3_k127_7406252_4 - - - - 0.0000000000000004536 85.0
HFD3_k127_7406252_5 Cupin 2, conserved barrel domain protein - - - 0.0000000000008929 75.0
HFD3_k127_7419538_0 - - - - 0.00000000000000000000000000000000000000000000000000000004129 210.0
HFD3_k127_7419538_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000474 154.0
HFD3_k127_7419538_2 - - - - 0.000000000000000000000000000000000001862 142.0
HFD3_k127_7419538_3 - - - - 0.0000000000000000001315 94.0
HFD3_k127_7419538_4 PQQ-like domain K00114 - 1.1.2.8 0.000000000000000006671 90.0
HFD3_k127_7422631_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 574.0
HFD3_k127_7422631_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 385.0
HFD3_k127_7422631_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000001033 233.0
HFD3_k127_7423170_0 Fumarase C C-terminus K01679 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 586.0
HFD3_k127_7423170_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005404 514.0
HFD3_k127_7423170_10 Amidohydrolase family K01443 - 3.5.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 306.0
HFD3_k127_7423170_11 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008052 289.0
HFD3_k127_7423170_12 PFAM transferase hexapeptide repeat containing protein K00966 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005769 290.0
HFD3_k127_7423170_13 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003339 279.0
HFD3_k127_7423170_14 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004046 274.0
HFD3_k127_7423170_15 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006204 276.0
HFD3_k127_7423170_16 COG0685 5,10-methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000005056 268.0
HFD3_k127_7423170_17 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001096 265.0
HFD3_k127_7423170_18 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007314 256.0
HFD3_k127_7423170_19 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000007906 248.0
HFD3_k127_7423170_2 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835,K01840 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004084 419.0
HFD3_k127_7423170_20 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000000001442 235.0
HFD3_k127_7423170_21 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000001343 243.0
HFD3_k127_7423170_22 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000000000000000000000004955 229.0
HFD3_k127_7423170_23 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000000001843 194.0
HFD3_k127_7423170_24 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.00000000000000000000000000000000000000000000000006599 189.0
HFD3_k127_7423170_25 PFAM Nickel cobalt transporter, high-affinity - - - 0.0000000000000000000000000000000000000000000005297 175.0
HFD3_k127_7423170_26 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000001525 165.0
HFD3_k127_7423170_27 Putative restriction endonuclease - - - 0.0000000000000000000000000000000000000000001004 168.0
HFD3_k127_7423170_28 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000004889 158.0
HFD3_k127_7423170_29 Crossover junction endodeoxyribonuclease RuvC K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.00000000000000000000000000000000000000001473 158.0
HFD3_k127_7423170_3 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003773 382.0
HFD3_k127_7423170_30 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000002029 154.0
HFD3_k127_7423170_31 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000128 159.0
HFD3_k127_7423170_32 - - - - 0.000000000000000000000000000000000002525 154.0
HFD3_k127_7423170_33 Methyltransferase type 11 - - - 0.000000000000000000000000000000001843 141.0
HFD3_k127_7423170_34 Protein conserved in bacteria - - - 0.000000000000000000000000001538 124.0
HFD3_k127_7423170_35 Glycosyltransferase like family 2 - - - 0.00000000000000000000000008654 119.0
HFD3_k127_7423170_36 glycolate biosynthetic process K01091 - 3.1.3.18 0.000000000000000000000001307 112.0
HFD3_k127_7423170_37 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0000000000000000003223 100.0
HFD3_k127_7423170_38 - - - - 0.0000000000000000009924 91.0
HFD3_k127_7423170_39 AntiSigma factor - - - 0.0000000000000001179 88.0
HFD3_k127_7423170_4 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007279 336.0
HFD3_k127_7423170_40 Peptidoglycan-binding LysM - - - 0.0000000000000008611 90.0
HFD3_k127_7423170_41 PFAM Protein kinase domain K12132 - 2.7.11.1 0.000000000000001124 82.0
HFD3_k127_7423170_42 gag-polyprotein putative aspartyl protease - - - 0.0000000000002885 83.0
HFD3_k127_7423170_43 Polysaccharide biosynthesis protein - - - 0.0000000000003576 83.0
HFD3_k127_7423170_45 - - - - 0.000007896 51.0
HFD3_k127_7423170_46 Belongs to the 'phage' integrase family K04763 - - 0.00001675 50.0
HFD3_k127_7423170_5 Transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 326.0
HFD3_k127_7423170_6 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 318.0
HFD3_k127_7423170_7 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 312.0
HFD3_k127_7423170_8 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 317.0
HFD3_k127_7423170_9 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722 312.0
HFD3_k127_7434265_0 Isocitrate dehydrogenase K00031 - 1.1.1.42 0.0 1085.0
HFD3_k127_7434265_1 Belongs to the IlvD Edd family - - - 4.887e-295 912.0
HFD3_k127_7434265_10 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000000000000000000000000000000000000000002521 205.0
HFD3_k127_7434265_11 YjbR - - - 0.0000000000000000000000000000000000000000167 161.0
HFD3_k127_7434265_12 Glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.000000000000000000000000000000000004209 141.0
HFD3_k127_7434265_13 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000006521 115.0
HFD3_k127_7434265_14 COG0671 Membrane-associated phospholipid phosphatase K19302 - 3.6.1.27 0.0000000000000000000000007637 110.0
HFD3_k127_7434265_15 - - - - 0.000000000000000000001777 101.0
HFD3_k127_7434265_17 Cytochrome c K17760 - 1.1.9.1 0.00000000000005258 80.0
HFD3_k127_7434265_18 - - - - 0.000000006416 65.0
HFD3_k127_7434265_19 Transcriptional regulator - - - 0.00008835 48.0
HFD3_k127_7434265_2 RNA polymerase recycling family C-terminal - - - 1.525e-260 830.0
HFD3_k127_7434265_3 Dehydrogenase K00114 - 1.1.2.8 2.565e-216 685.0
HFD3_k127_7434265_4 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01576,K01652 - 2.2.1.6,4.1.1.7 1.409e-206 661.0
HFD3_k127_7434265_5 COG0076 Glutamate decarboxylase and related PLP-dependent K01593 - 4.1.1.105,4.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004582 589.0
HFD3_k127_7434265_6 PFAM Aldo keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006571 373.0
HFD3_k127_7434265_7 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 332.0
HFD3_k127_7434265_8 N-acetylglucosaminylinositol deacetylase activity K22135 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 287.0
HFD3_k127_7434265_9 Amidohydrolase K10221 - 3.1.1.57 0.00000000000000000000000000000000000000000000000000000000000003204 225.0
HFD3_k127_7446600_0 COG1012 NAD-dependent aldehyde - - - 4.947e-194 617.0
HFD3_k127_7446600_1 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 569.0
HFD3_k127_7446600_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 541.0
HFD3_k127_7446600_3 beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004965 418.0
HFD3_k127_7446600_4 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 369.0
HFD3_k127_7446600_5 adenylate kinase activity - - - 0.000000000000000000000000000000000000000000000000000002214 197.0
HFD3_k127_7501066_0 PQQ-like domain K00114 - 1.1.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003427 523.0
HFD3_k127_7501066_1 Belongs to the carbamate kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006247 361.0
HFD3_k127_7501066_10 - - - - 0.0000000000000000000000005105 109.0
HFD3_k127_7501066_11 COG2133 Glucose sorbosone dehydrogenases - - - 0.00011 53.0
HFD3_k127_7501066_2 Glycosyl transferase, family 2 K20534 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004629 332.0
HFD3_k127_7501066_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008505 299.0
HFD3_k127_7501066_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000002126 262.0
HFD3_k127_7501066_5 PQQ-like domain K00114 - 1.1.2.8 0.000000000000000000000000000000000000000000000001056 181.0
HFD3_k127_7501066_6 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000000000000009443 173.0
HFD3_k127_7501066_7 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000005186 144.0
HFD3_k127_7501066_8 - - - - 0.00000000000000000000000000000005904 136.0
HFD3_k127_7501066_9 - - - - 0.000000000000000000000000000006856 136.0
HFD3_k127_7531867_0 cobalamin-transporting ATPase activity K02014,K16092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 576.0
HFD3_k127_7531867_1 ANTAR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 411.0
HFD3_k127_7531867_10 Protein of unknown function (DUF507) - - - 0.00000000000000096 80.0
HFD3_k127_7531867_11 - - - - 0.000000003205 60.0
HFD3_k127_7531867_2 FecCD transport family K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005565 335.0
HFD3_k127_7531867_3 ABC-type Fe3 -hydroxamate transport system, periplasmic K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 333.0
HFD3_k127_7531867_4 PFAM ABC transporter related K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 308.0
HFD3_k127_7531867_5 PepSY-associated TM region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000048 305.0
HFD3_k127_7531867_6 PFAM Adenosylcobinamide amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001861 248.0
HFD3_k127_7531867_7 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000000000000000000000000000000000000000000000000000001822 218.0
HFD3_k127_7531867_8 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000001208 177.0
HFD3_k127_7531867_9 Protein of unknown function (DUF507) K09804 - - 0.0000000000000000000004522 98.0
HFD3_k127_7541043_0 PFAM Cytochrome c assembly protein K02198 - - 1.02e-200 645.0
HFD3_k127_7541043_1 ABC transporter K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000000000000003175 203.0
HFD3_k127_7541043_10 - - - - 0.000000005393 64.0
HFD3_k127_7541043_2 PFAM Fibronectin type III domain - - - 0.000000000000000000000000000000000000000000000000002742 209.0
HFD3_k127_7541043_3 Cytochrome C assembly protein K02195 GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016021,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0031224,GO:0031226,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044425,GO:0044459,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 - 0.00000000000000000000000000000000000000000000000002023 186.0
HFD3_k127_7541043_4 PFAM cytochrome c-type biogenesis protein CcmB K02194 - - 0.0000000000000000000000000000000000000000000001615 175.0
HFD3_k127_7541043_5 Belongs to the peptidase S8 family K01342,K13275 - 3.4.21.62 0.000000000000000000000000000000115 145.0
HFD3_k127_7541043_6 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000005257 129.0
HFD3_k127_7541043_7 Cytochrome P460 - - - 0.0000000000000000000000137 111.0
HFD3_k127_7541043_8 cytochrome complex assembly K02198,K02200,K04016,K04017,K04018 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098567,GO:1901564 - 0.0000000000000000000004035 102.0
HFD3_k127_7541043_9 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000003969 98.0
HFD3_k127_7548971_0 Dehydrogenase K00117 - 1.1.5.2 2.798e-308 959.0
HFD3_k127_7548971_1 Molybdopterin oxidoreductase Fe4S4 domain K08357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 544.0
HFD3_k127_7548971_10 Protein of unknown function (DUF3341) - - - 0.000000000000004557 86.0
HFD3_k127_7548971_11 Protein of unknown function (DUF983) - - - 0.0000001096 60.0
HFD3_k127_7548971_2 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007755 536.0
HFD3_k127_7548971_3 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006232 443.0
HFD3_k127_7548971_4 PFAM Glucose Sorbosone dehydrogenase K21430 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 343.0
HFD3_k127_7548971_5 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003466 329.0
HFD3_k127_7548971_6 Belongs to the UPF0234 family K09767 - - 0.000000000000000000000000000000000000000000000000000000000000003159 222.0
HFD3_k127_7548971_7 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000001255 146.0
HFD3_k127_7548971_8 Protein of unknown function (DUF1552) - - - 0.000000000000000000000000002108 113.0
HFD3_k127_7548971_9 Tetratricopeptide repeat - - - 0.000000000000000000000003198 116.0
HFD3_k127_761728_0 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003108 543.0
HFD3_k127_761728_1 Pyrrolo-quinoline quinone K17760,K20936 - 1.1.2.9,1.1.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006476 535.0
HFD3_k127_761728_10 Tetratricopeptide repeat - - - 0.000000000000000000001531 110.0
HFD3_k127_761728_11 Metallo-beta-lactamase superfamily - - - 0.0000000000000000001944 96.0
HFD3_k127_761728_12 lipolytic protein G-D-S-L family - - - 0.00000000000003479 76.0
HFD3_k127_761728_13 domain protein - - - 0.00000000003039 74.0
HFD3_k127_761728_14 TonB dependent receptor - - - 0.000000006353 64.0
HFD3_k127_761728_15 Metallo-beta-lactamase superfamily - - - 0.00000001153 63.0
HFD3_k127_761728_16 Protein of unknown function (DUF3060) - - - 0.000008923 53.0
HFD3_k127_761728_17 domain protein K14194 - - 0.000009288 53.0
HFD3_k127_761728_18 Carboxypeptidase regulatory-like domain - - - 0.0002213 54.0
HFD3_k127_761728_19 PPIC-type PPIASE domain K03769,K07533 - 5.2.1.8 0.0006354 53.0
HFD3_k127_761728_2 Tannase and feruloyl esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 497.0
HFD3_k127_761728_3 Polysaccharide biosynthesis protein K18981 - 1.1.1.203 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 464.0
HFD3_k127_761728_4 TIGRFAM Na H antiporter, bacterial form K03316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008999 398.0
HFD3_k127_761728_5 ankyrin repeat K15503 - - 0.00000000000000000000000000000000000000000000000000000002671 217.0
HFD3_k127_761728_6 - - - - 0.000000000000000000000000000000000000000000000001352 180.0
HFD3_k127_761728_7 GDSL-like Lipase/Acylhydrolase K10804 - 3.1.1.5 0.0000000000000000000000000000000008188 138.0
HFD3_k127_761728_8 Endonuclease Exonuclease Phosphatase - - - 0.000000000000000000000000000000003459 139.0
HFD3_k127_761728_9 transcriptional regulators - - - 0.00000000000000000000008579 102.0
HFD3_k127_7620590_0 SPFH domain / Band 7 family - - - 4.202e-260 819.0
HFD3_k127_7620590_1 radical SAM domain protein - - - 5.643e-222 698.0
HFD3_k127_7620590_10 domain protein K14194 - - 0.0000000009611 72.0
HFD3_k127_7620590_2 Sir2 family K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 293.0
HFD3_k127_7620590_3 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000009535 260.0
HFD3_k127_7620590_4 Belongs to the glycosyl hydrolase 13 family K07214 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005999 250.0
HFD3_k127_7620590_5 Hydrolase of the alpha beta-hydrolase K07020 - - 0.00000000000000000000000000000000000000000000003084 178.0
HFD3_k127_7620590_6 - - - - 0.00000000000000000000000002054 120.0
HFD3_k127_7620590_7 pathogenesis - - - 0.0000000000000000000000003119 114.0
HFD3_k127_7620590_8 Penicillinase repressor - - - 0.0000000000000000001814 92.0
HFD3_k127_7620590_9 methyltransferase - - - 0.0000000002854 70.0
HFD3_k127_7621065_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01874 - 6.1.1.10 6.993e-306 947.0
HFD3_k127_7621065_1 2-keto-3-deoxy-L-rhamnonate aldolase activity K02510 - 4.1.2.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004599 438.0
HFD3_k127_7621065_2 Belongs to the aldehyde dehydrogenase family K22187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000568 375.0
HFD3_k127_7621065_3 Iron-containing alcohol dehydrogenase K00001,K13954 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 302.0
HFD3_k127_7621065_4 Malate/L-lactate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001058 283.0
HFD3_k127_7639949_0 Radical SAM - - - 1.04e-293 917.0
HFD3_k127_7639949_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 2.168e-287 892.0
HFD3_k127_7639949_10 Tetratricopeptide repeat - - - 0.000000000000000000000000000000004455 147.0
HFD3_k127_7639949_11 Uncharacterized conserved protein (DUF2203) - - - 0.00000000000000000000000001355 113.0
HFD3_k127_7639949_12 Pfam:DUF59 - - - 0.00000000000000000000001307 106.0
HFD3_k127_7639949_13 Protein of unknown function (DUF4197) - - - 0.00000000000000001443 82.0
HFD3_k127_7639949_14 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000893 72.0
HFD3_k127_7639949_2 COGs COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006191 464.0
HFD3_k127_7639949_3 PQQ-like domain K05889 - 1.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 458.0
HFD3_k127_7639949_4 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005366 410.0
HFD3_k127_7639949_5 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004762 289.0
HFD3_k127_7639949_6 arylformamidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000542 289.0
HFD3_k127_7639949_7 e3 binding domain K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000001247 265.0
HFD3_k127_7639949_8 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0000000000000000000000000000000000000000002205 166.0
HFD3_k127_7639949_9 Belongs to the HesB IscA family - - - 0.00000000000000000000000000000000003207 136.0
HFD3_k127_7663232_0 Belongs to the ABC transporter superfamily K02031,K02032 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 1.445e-318 987.0
HFD3_k127_7663232_1 Glycogen debranching enzyme - - - 4.421e-234 742.0
HFD3_k127_7663232_10 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009641 430.0
HFD3_k127_7663232_11 ABC transporter (Permease) K02033,K13894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 422.0
HFD3_k127_7663232_12 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 409.0
HFD3_k127_7663232_13 microcin transport K13895 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008951 403.0
HFD3_k127_7663232_14 TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002953 379.0
HFD3_k127_7663232_15 N-terminal TM domain of oligopeptide transport permease C K02034 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004277 363.0
HFD3_k127_7663232_16 NMT1-like family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 309.0
HFD3_k127_7663232_17 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000007552 266.0
HFD3_k127_7663232_18 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000000000002627 226.0
HFD3_k127_7663232_19 RNA polymerase sigma factor K03088 - - 0.00000000000000000000000000000000000000001397 169.0
HFD3_k127_7663232_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 GO:0003674,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0017038,GO:0022857,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0033036,GO:0033218,GO:0042277,GO:0042597,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043295,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0048037,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072341,GO:1900750,GO:1901681,GO:1904680 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 615.0
HFD3_k127_7663232_20 Cupin domain - - - 0.0000000000000000000000001195 112.0
HFD3_k127_7663232_21 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000001164 89.0
HFD3_k127_7663232_22 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000002326 89.0
HFD3_k127_7663232_23 Putative zinc-finger - - - 0.0000000003441 64.0
HFD3_k127_7663232_24 Tetratricopeptide TPR_2 repeat protein - - - 0.000001441 60.0
HFD3_k127_7663232_25 - - - - 0.00005689 52.0
HFD3_k127_7663232_3 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 605.0
HFD3_k127_7663232_4 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005118 630.0
HFD3_k127_7663232_5 class II (D K K01876,K09759,K22503 - 6.1.1.12,6.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003351 578.0
HFD3_k127_7663232_6 alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 563.0
HFD3_k127_7663232_7 transmembrane transport K13893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 556.0
HFD3_k127_7663232_8 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009174 473.0
HFD3_k127_7663232_9 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005467 428.0
HFD3_k127_7702327_0 PrpF protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006356 484.0
HFD3_k127_7702327_1 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008044 404.0
HFD3_k127_7702327_10 - - - - 0.0000000000000000000000000000002749 127.0
HFD3_k127_7702327_11 von willebrand factor type a K07114 - - 0.000000749 60.0
HFD3_k127_7702327_2 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000008136 222.0
HFD3_k127_7702327_3 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000000000000000000000000000000000005542 204.0
HFD3_k127_7702327_4 - - - - 0.00000000000000000000000000000000000000000000000001276 190.0
HFD3_k127_7702327_5 NHL repeat - - - 0.0000000000000000000000000000000000000000000001706 183.0
HFD3_k127_7702327_6 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.0000000000000000000000000000000000003287 151.0
HFD3_k127_7702327_8 Bacterial extracellular solute-binding protein K02020,K22003 - 5.3.3.7 0.0000000000000000000000000000000564 134.0
HFD3_k127_7702327_9 tungstate binding K02020 - - 0.0000000000000000000000000000001311 134.0
HFD3_k127_771113_0 Integrase core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005596 410.0
HFD3_k127_771113_1 Integrase core domain - - - 0.0000000000000000000000000000000000000128 146.0
HFD3_k127_771113_2 Histidine kinase - - - 0.00000001942 56.0
HFD3_k127_7727950_0 DNA topological change K03168 - 5.99.1.2 1.513e-259 820.0
HFD3_k127_7727950_1 Protein of unknown function (DUF1552) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 449.0
HFD3_k127_7727950_2 response to abiotic stimulus K06867 - - 0.00000000000000009476 84.0
HFD3_k127_77668_0 MutL protein - - - 1.944e-293 912.0
HFD3_k127_77668_1 Short chain fatty acid transporter K02106 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 493.0
HFD3_k127_77668_10 - - - - 0.00000000000000001501 87.0
HFD3_k127_77668_2 serine-type peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 447.0
HFD3_k127_77668_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 438.0
HFD3_k127_77668_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 389.0
HFD3_k127_77668_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007793 382.0
HFD3_k127_77668_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005949 372.0
HFD3_k127_77668_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002561 302.0
HFD3_k127_77668_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002491 262.0
HFD3_k127_77668_9 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000000000000000000002176 190.0
HFD3_k127_793366_0 PQQ enzyme repeat K00117 - 1.1.5.2 9.616e-198 638.0
HFD3_k127_793366_1 belongs to the thioredoxin family K20444,K20543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 429.0
HFD3_k127_793366_2 regulatory protein, FmdB family - - - 0.00000000002338 72.0
HFD3_k127_793366_3 DNA topological change - - - 0.00000302 52.0
HFD3_k127_80767_0 2-methylcitrate dehydratase activity K01720 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019679,GO:0019752,GO:0030312,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046459,GO:0047547,GO:0050896,GO:0071704,GO:0071944,GO:0072329,GO:1901575 4.2.1.79 1.159e-216 680.0
HFD3_k127_80767_1 methylisocitrate lyase activity K03417 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006113,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0046421,GO:0046459,GO:0046872,GO:0055114,GO:0071704,GO:0072329,GO:1901575 4.1.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000624 272.0
HFD3_k127_80767_2 Enoyl-CoA hydratase/isomerase K13767,K13816 - 4.2.1.17 0.0000000000000000000000000000000001501 136.0
HFD3_k127_807784_0 Elongation factor G C-terminus K06207 - - 0.0 1054.0
HFD3_k127_807784_2 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000007834 114.0
HFD3_k127_812902_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006524 617.0
HFD3_k127_812902_1 metalloendopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006623 542.0
HFD3_k127_812902_2 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009828 492.0
HFD3_k127_812902_3 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 303.0
HFD3_k127_812902_4 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002799 253.0
HFD3_k127_812902_5 recA bacterial DNA recombination protein - - - 0.000000000000000000000000000000000000000000003926 173.0
HFD3_k127_812902_6 Haloacid dehalogenase-like hydrolase K17623 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005975,GO:0006066,GO:0006071,GO:0006114,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019400,GO:0019401,GO:0019751,GO:0034637,GO:0042578,GO:0043136,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046173,GO:0071704,GO:1901576,GO:1901615,GO:1901617 3.1.3.96 0.0000000000000000000000000000000000002473 147.0
HFD3_k127_812902_7 2OG-Fe(II) oxygenase superfamily K03919 - 1.14.11.33 0.00000000000000000000000000000000002467 138.0
HFD3_k127_812902_8 nucleoside 2-deoxyribosyltransferase - - - 0.000000000000005817 84.0
HFD3_k127_820998_0 Aminotransferase class-III K00823 - 2.6.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 516.0
HFD3_k127_820998_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003357 515.0
HFD3_k127_820998_2 ABC transporter, ATP-binding protein K10010 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001789 250.0
HFD3_k127_820998_3 oxidoreductase activity K12511 - - 0.00000000000000000000000000000000000000000000000000000000000001514 225.0
HFD3_k127_820998_4 proteolysis K03665 - - 0.000000000000000000000000000000001553 136.0
HFD3_k127_820998_5 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000001537 122.0
HFD3_k127_820998_6 Belongs to the UPF0102 family K07460 - - 0.00000000000000000001913 95.0
HFD3_k127_820998_7 - - - - 0.0001746 44.0
HFD3_k127_820998_8 - - - - 0.0008989 42.0
HFD3_k127_838409_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 2.818e-262 819.0
HFD3_k127_838409_1 Aldehyde dehydrogenase family K00294,K13821 - 1.2.1.88,1.5.5.2 2.004e-221 698.0
HFD3_k127_838409_10 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 342.0
HFD3_k127_838409_11 Radical SAM superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 324.0
HFD3_k127_838409_12 tRNA pseudouridine synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004852 295.0
HFD3_k127_838409_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001072 273.0
HFD3_k127_838409_14 Ankyrin repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001953 275.0
HFD3_k127_838409_15 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000007538 221.0
HFD3_k127_838409_16 - - - - 0.00000000000000000000000001016 121.0
HFD3_k127_838409_17 - - - - 0.0000000000000000000000005791 111.0
HFD3_k127_838409_18 Domain of unknown function (DUF4342) - - - 0.000000000002695 69.0
HFD3_k127_838409_2 DNA topological change K03168 - 5.99.1.2 1.622e-213 690.0
HFD3_k127_838409_20 by modhmm - - - 0.0003908 52.0
HFD3_k127_838409_21 Tetratricopeptide repeat - - - 0.0008911 51.0
HFD3_k127_838409_3 Molecular chaperone. Has ATPase activity K04079 GO:0000302,GO:0000303,GO:0000305,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0010035,GO:0016020,GO:0030312,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044464,GO:0050896,GO:0051716,GO:0070887,GO:0071450,GO:0071451,GO:0071944,GO:1901700,GO:1901701 - 2.146e-198 637.0
HFD3_k127_838409_4 TonB dependent receptor - - - 4.662e-196 638.0
HFD3_k127_838409_5 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004813 634.0
HFD3_k127_838409_6 peroxiredoxin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008148 419.0
HFD3_k127_838409_7 major facilitator superfamily MFS_1 K08225 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 387.0
HFD3_k127_838409_8 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009739 362.0
HFD3_k127_838409_9 pkhd-type hydroxylase K07336 GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0033554,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0098771 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 340.0
HFD3_k127_839478_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 3.597e-320 992.0
HFD3_k127_839478_1 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005725 474.0
HFD3_k127_839478_2 Sodium:sulfate symporter transmembrane region K14445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 406.0
HFD3_k127_839478_3 inositol monophosphate 1-phosphatase activity K01082,K01092 GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002328 273.0
HFD3_k127_839478_4 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000008064 214.0
HFD3_k127_839478_5 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000007617 141.0
HFD3_k127_839478_6 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000001379 129.0
HFD3_k127_839478_7 - - - - 0.00000000000000000005544 102.0
HFD3_k127_839478_8 Tetratricopeptide repeat - - - 0.000000001477 70.0
HFD3_k127_854183_0 ABC transporter - - - 2.227e-293 906.0
HFD3_k127_854183_1 metalloendopeptidase activity K08602 GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 3.237e-201 644.0
HFD3_k127_854183_10 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.0000000000000000000000001263 117.0
HFD3_k127_854183_11 - - - - 0.000000000000000000000002538 113.0
HFD3_k127_854183_12 Transposase K07483 - - 0.0000000000000002251 84.0
HFD3_k127_854183_13 PFAM ABC transporter - - - 0.000000000002438 66.0
HFD3_k127_854183_14 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000009386 59.0
HFD3_k127_854183_15 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000003122 55.0
HFD3_k127_854183_2 PFAM transposase IS66 K07484 - - 5.423e-200 636.0
HFD3_k127_854183_3 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 559.0
HFD3_k127_854183_4 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 389.0
HFD3_k127_854183_5 electron transfer activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 374.0
HFD3_k127_854183_6 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity K08080,K14952 - 1.14.18.2 0.000000000000000000000000000000000000000000000000000000000000000000001825 253.0
HFD3_k127_854183_7 D-arabinono-1,4-lactone oxidase K00594 - 1.1.3.41 0.000000000000000000000000000000000000000000000000000000000000000000001862 252.0
HFD3_k127_854183_8 PFAM IS66 Orf2 family protein K07484 - - 0.0000000000000000000000000000000000000000000000000000002508 195.0
HFD3_k127_854183_9 - - - - 0.000000000000000000000000000000001034 144.0
HFD3_k127_857979_0 Carboxypeptidase regulatory-like domain - - - 4.245e-199 664.0
HFD3_k127_857979_1 Dehydrogenase K00117 - 1.1.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 603.0
HFD3_k127_857979_2 COG1247 Sortase and related acyltransferases K03823 - 2.3.1.183 0.0000000000000000000000000000000000000000000000000000000000001532 219.0
HFD3_k127_857979_3 Domain of unknown function (DUF4112) - - - 0.000000000000000000000000000000001597 134.0
HFD3_k127_860563_0 XdhC and CoxI family K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005009 304.0
HFD3_k127_860563_1 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002205 280.0
HFD3_k127_860563_2 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000023 264.0
HFD3_k127_860563_3 ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000003544 237.0
HFD3_k127_860563_4 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000003078 199.0
HFD3_k127_860563_5 Sh3 type 3 domain protein - - - 0.000000000000000000000008785 112.0
HFD3_k127_860563_6 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000000000002035 90.0
HFD3_k127_860563_7 CO dehydrogenase flavoprotein C-terminal domain K16878 - 1.3.99.8 0.0000002338 61.0
HFD3_k127_860563_8 - - - - 0.00002072 49.0
HFD3_k127_875811_0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003714 523.0
HFD3_k127_875811_1 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009096 507.0
HFD3_k127_87621_0 Voltage gated chloride channel - - - 1.51e-260 814.0
HFD3_k127_87621_1 cellulose binding - - - 1.896e-225 700.0
HFD3_k127_87621_10 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003108 278.0
HFD3_k127_87621_11 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.00000000000000000000000000000000000000005032 156.0
HFD3_k127_87621_12 MarR family - - - 0.000000000000000000000000000000000000001327 153.0
HFD3_k127_87621_13 YCII-related domain - - - 0.000000000000000000000000000000000001748 144.0
HFD3_k127_87621_14 - - - - 0.00000000000000000000000005708 115.0
HFD3_k127_87621_2 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 560.0
HFD3_k127_87621_3 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 551.0
HFD3_k127_87621_4 Converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 503.0
HFD3_k127_87621_5 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004637 524.0
HFD3_k127_87621_6 Cys/Met metabolism PLP-dependent enzyme K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 492.0
HFD3_k127_87621_7 Domain of unknown function (DUF1972) K12996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 417.0
HFD3_k127_87621_8 Peptidase dimerisation domain K01295 - 3.4.17.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 355.0
HFD3_k127_87621_9 PFAM phosphoesterase, RecJ domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 327.0
HFD3_k127_895410_0 B12 binding domain - - - 1.229e-315 972.0
HFD3_k127_895410_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 545.0
HFD3_k127_895410_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000002706 253.0
HFD3_k127_901435_0 Periplasmic binding protein LacI transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007097 537.0
HFD3_k127_901435_1 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000004801 237.0
HFD3_k127_901435_2 PFAM lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000005209 175.0
HFD3_k127_902787_0 FAD linked oxidases, C-terminal domain K00803 - 2.5.1.26 7.822e-223 706.0
HFD3_k127_902787_1 Male sterility protein K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004374 363.0
HFD3_k127_902787_2 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004031 266.0
HFD3_k127_902787_3 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000003048 205.0
HFD3_k127_902787_4 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.00000000000000000000000000000000000000000000000000003982 202.0
HFD3_k127_902787_5 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000004761 189.0
HFD3_k127_902787_6 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000004409 104.0
HFD3_k127_902787_7 Metallo-beta-lactamase superfamily - - - 0.00000000002845 74.0
HFD3_k127_910919_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 5.003e-272 846.0
HFD3_k127_910919_1 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 513.0
HFD3_k127_910919_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004231 471.0
HFD3_k127_910919_3 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005564 436.0
HFD3_k127_910919_4 Catalytic domain of components of various dehydrogenase complexes K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 432.0
HFD3_k127_910919_5 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 GO:0000271,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901576 2.7.7.27 0.0000000000000000134 86.0
HFD3_k127_910919_6 Phosphopantetheine attachment site - - - 0.00000000000000005165 84.0
HFD3_k127_910919_7 Bacterial periplasmic substrate-binding proteins - - - 0.0000000000000002659 85.0
HFD3_k127_919315_0 SNF2 family N-terminal domain - - - 0.0 1166.0
HFD3_k127_919315_1 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 568.0
HFD3_k127_919315_10 Uncharacterized conserved protein (COG2071) - - - 0.000000000000000000000000000000000000000000000000000000000000000000007623 241.0
HFD3_k127_919315_11 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000001143 204.0
HFD3_k127_919315_12 Bacterial protein of unknown function (DUF882) - - - 0.0000000000000000000000000000000000000000000000000000218 194.0
HFD3_k127_919315_13 Uncharacterized conserved protein (COG2071) K09166 - - 0.000000000000000000000000000000000000000000000000001837 191.0
HFD3_k127_919315_14 EVE domain - - - 0.000000000000000000000000000000000000000000001743 167.0
HFD3_k127_919315_15 Methyltransferase domain - - - 0.0000000000000000000000000000000000000001691 159.0
HFD3_k127_919315_16 Transglycosylase associated protein - - - 0.000000000000000000000000000006013 121.0
HFD3_k127_919315_17 - - - - 0.0000000000000000000000000003059 126.0
HFD3_k127_919315_18 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000006042 115.0
HFD3_k127_919315_19 Protein of unknown function (DUF4242) - - - 0.000000000000000000003318 100.0
HFD3_k127_919315_2 DNA polymerase K02347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 532.0
HFD3_k127_919315_20 PFAM SNARE associated Golgi protein - - - 0.00000000000000000001695 100.0
HFD3_k127_919315_21 ubiE/COQ5 methyltransferase family K07755 - 2.1.1.137 0.0000000000000000001814 92.0
HFD3_k127_919315_22 - - - - 0.00000000000000003931 94.0
HFD3_k127_919315_23 - - - - 0.0000001905 63.0
HFD3_k127_919315_24 YtxH-like protein - - - 0.0000005779 57.0
HFD3_k127_919315_3 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002899 447.0
HFD3_k127_919315_4 PFAM short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 302.0
HFD3_k127_919315_5 SWIM zinc finger - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007923 300.0
HFD3_k127_919315_6 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005718 300.0
HFD3_k127_919315_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 304.0
HFD3_k127_919315_8 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003704 284.0
HFD3_k127_919315_9 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003547 265.0
HFD3_k127_921856_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 3.642e-309 960.0
HFD3_k127_921856_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 596.0
HFD3_k127_921856_10 metallophosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000002902 233.0
HFD3_k127_921856_11 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000006458 196.0
HFD3_k127_921856_12 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.00000000000000000000000000000000000000000239 162.0
HFD3_k127_921856_13 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000002525 109.0
HFD3_k127_921856_14 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000001333 107.0
HFD3_k127_921856_2 Osmosensitive K channel His kinase sensor K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005096 458.0
HFD3_k127_921856_3 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 452.0
HFD3_k127_921856_4 Type II secretion system protein E K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 432.0
HFD3_k127_921856_5 SpoIVB peptidase S55 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 391.0
HFD3_k127_921856_6 Peptidase M1, membrane alanine aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 381.0
HFD3_k127_921856_7 Osmosensitive K channel His kinase sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 365.0
HFD3_k127_921856_8 Histidine kinase K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004154 308.0
HFD3_k127_921856_9 Two component transcriptional regulator, winged helix family K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007797 269.0
HFD3_k127_922080_0 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 345.0
HFD3_k127_922080_1 Radical SAM superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003954 272.0
HFD3_k127_922080_2 photosynthesis - - - 0.000000000000000000000000000000000000000000000000000382 188.0
HFD3_k127_922080_3 Glycosyl transferase family 21 - - - 0.0000000000000000000000000001383 121.0
HFD3_k127_939385_0 Peptidase M61 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001413 295.0
HFD3_k127_939385_1 Belongs to the Nudix hydrolase family - - - 0.0000000000000000000001121 102.0
HFD3_k127_964235_0 Dicarboxylate carrier MatC domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005434 353.0
HFD3_k127_964235_1 Thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003743 256.0
HFD3_k127_964235_2 amino acid aldolase or racemase K18425 - 4.1.3.41 0.000000000000000000000000000000000000000000000000000000000000000000000002788 258.0
HFD3_k127_964235_3 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06137 - 1.3.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000001691 247.0
HFD3_k127_964235_4 phospholipase Carboxylesterase - - - 0.0000000000000000000000000000000000000006794 154.0
HFD3_k127_964235_5 von Willebrand factor (vWF) type A domain K07114 - - 0.000000000000000000000000000000000004626 150.0
HFD3_k127_964329_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1046.0
HFD3_k127_964329_1 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000003087 268.0
HFD3_k127_964329_2 Cytochrome P460 - - - 0.0000000000000000000000000000000000000000000000000000000000001151 218.0
HFD3_k127_964329_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000003735 184.0
HFD3_k127_964329_4 PFAM outer membrane efflux protein K15725 - - 0.0000000000000000000000000000001148 139.0
HFD3_k127_964329_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000001469 62.0
HFD3_k127_964385_0 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 508.0
HFD3_k127_964385_1 Oxidoreductase molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003849 276.0
HFD3_k127_982925_0 Urocanase Rossmann-like domain K01712 - 4.2.1.49 1.756e-269 837.0
HFD3_k127_982925_1 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 5.194e-218 693.0
HFD3_k127_982925_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 360.0
HFD3_k127_982925_11 Amidohydrolase family K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 363.0
HFD3_k127_982925_12 gntR family - - - 0.000000000000000000000000000000000000000000000000000000000517 210.0
HFD3_k127_982925_13 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K00330 - 1.6.5.3 0.000000000000000000000000000000000000000000009702 165.0
HFD3_k127_982925_14 TIGRFAM NADH-quinone oxidoreductase, E subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000000002529 163.0
HFD3_k127_982925_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000000008746 130.0
HFD3_k127_982925_16 PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000000000000006179 123.0
HFD3_k127_982925_17 Belongs to the GSP D family K02453 - - 0.0000000000000001411 94.0
HFD3_k127_982925_2 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004669 577.0
HFD3_k127_982925_3 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004412 603.0
HFD3_k127_982925_4 Aromatic amino acid lyase K01745 - 4.3.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 543.0
HFD3_k127_982925_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 542.0
HFD3_k127_982925_6 PFAM Formiminotransferase domain K00603,K13990 - 2.1.2.5,4.3.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 470.0
HFD3_k127_982925_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004709 442.0
HFD3_k127_982925_8 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 447.0
HFD3_k127_982925_9 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005028 380.0
HFD3_k127_996730_0 AcrB/AcrD/AcrF family - - - 0.0 1386.0
HFD3_k127_996730_1 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 612.0
HFD3_k127_996730_10 - - - - 0.0000000000000000000000000000000000000000000004271 173.0
HFD3_k127_996730_11 Putative restriction endonuclease - - - 0.000000000000000000000000000000000000001488 156.0
HFD3_k127_996730_12 Protein of unknown function (DUF423) - - - 0.00000000000000000000000000000000000002478 147.0
HFD3_k127_996730_13 BON domain - - - 0.000000000000000007789 97.0
HFD3_k127_996730_14 Domain of unknown function (DU1801) - - - 0.00000000000001168 76.0
HFD3_k127_996730_15 SnoaL-like domain - - - 0.000000926 55.0
HFD3_k127_996730_2 DNA ligase K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 407.0
HFD3_k127_996730_3 outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 402.0
HFD3_k127_996730_4 RNA-3'-phosphate cyclase activity K01974 GO:0003674,GO:0003824,GO:0003963,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009975,GO:0016874,GO:0016886,GO:0044424,GO:0044464,GO:0140098 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009527 397.0
HFD3_k127_996730_5 Phospholipase D Transphosphatidylase K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 398.0
HFD3_k127_996730_6 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 374.0
HFD3_k127_996730_7 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001768 252.0
HFD3_k127_996730_8 Cation transporter/ATPase, N-terminus K01531,K12955 - 3.6.3.2 0.000000000000000000000000000000000000000000000000000000000000001967 231.0
HFD3_k127_996730_9 - - - - 0.00000000000000000000000000000000000000000000000003917 185.0
HFD3_k127_999000_0 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006871 394.0
HFD3_k127_999000_1 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006528 391.0
HFD3_k127_999000_10 decarboxylase K01607 - 4.1.1.44 0.000000000000006113 83.0
HFD3_k127_999000_2 AntiSigma factor - - - 0.000000000000000000000000000000000000000000000000000000000000000000008694 243.0
HFD3_k127_999000_3 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000000002915 200.0
HFD3_k127_999000_4 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000009938 185.0
HFD3_k127_999000_5 Isochorismatase family - - - 0.000000000000000000000000000293 123.0
HFD3_k127_999000_6 Cupredoxin-like domain K02275 - 1.9.3.1 0.000000000000000000000000002799 119.0
HFD3_k127_999000_7 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000004159 104.0
HFD3_k127_999000_8 Protein of unknown function (DUF3738) K02172 - - 0.00000000000000000001156 104.0
HFD3_k127_999000_9 domain protein K14194 - - 0.000000000000004092 81.0