Overview

ID MAG01678
Name HFD3_bin.16
Sample SMP0045
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Blastocatellia
Order Pyrinomonadales
Family Pyrinomonadaceae
Genus OLB17
Species
Assembly information
Completeness (%) 89.46
Contamination (%) 1.84
GC content (%) 54.0
N50 (bp) 6,365
Genome size (bp) 3,275,600

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2913

Gene name Description KEGG GOs EC E-value Score Sequence
HFD3_k127_102047_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 421.0
HFD3_k127_102047_1 Enoyl-(Acyl carrier protein) reductase K00034,K03366 - 1.1.1.304,1.1.1.47,1.1.1.76 0.00000000000000000000000000000000000000000000000000002389 196.0
HFD3_k127_102047_2 Monogalactosyldiacylglycerol (MGDG) synthase K03715 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006643,GO:0006664,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008194,GO:0008378,GO:0009267,GO:0009507,GO:0009526,GO:0009527,GO:0009536,GO:0009605,GO:0009707,GO:0009941,GO:0009987,GO:0009991,GO:0016020,GO:0016036,GO:0016740,GO:0016757,GO:0016758,GO:0019374,GO:0019752,GO:0019867,GO:0031090,GO:0031667,GO:0031668,GO:0031669,GO:0031967,GO:0031968,GO:0031969,GO:0031975,GO:0032787,GO:0033554,GO:0035250,GO:0042170,GO:0042594,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0098588,GO:0098805,GO:1901135,GO:1903509 2.4.1.46 0.000000000000000000000000000000000003816 152.0
HFD3_k127_102047_3 Erythromycin esterase K06880 - - 0.000000000000000000000000000000008304 141.0
HFD3_k127_102047_4 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000001605 141.0
HFD3_k127_102047_5 Zinc carboxypeptidase - - - 0.000000000000000009288 95.0
HFD3_k127_1023249_0 Mur ligase family, catalytic domain K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 443.0
HFD3_k127_1023249_1 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006582 292.0
HFD3_k127_1023249_2 Stage II sporulation D domain protein K06381 - - 0.000000000000000000000000000000001738 148.0
HFD3_k127_1023249_3 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.000000000000000000000000000001375 123.0
HFD3_k127_1023249_4 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000157 124.0
HFD3_k127_1023249_5 tetratricopeptide repeat - - - 0.00000000000000003206 96.0
HFD3_k127_103040_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006249 459.0
HFD3_k127_103040_1 - - - - 0.00000000000000000000000009825 111.0
HFD3_k127_103040_2 Domain of unknown function (DUF4440) - - - 0.00000000000000000005235 92.0
HFD3_k127_103040_3 Protein of unknown function (DUF2695) - - - 0.00000000006344 68.0
HFD3_k127_103920_0 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009692 486.0
HFD3_k127_103920_1 Natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 420.0
HFD3_k127_103920_2 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000009387 214.0
HFD3_k127_103920_3 Belongs to the Fur family K03711 - - 0.00000000000000000000000000002262 120.0
HFD3_k127_1052517_0 Peptidase S46 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000611 608.0
HFD3_k127_1052517_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003751 253.0
HFD3_k127_1052517_2 Aminotransferase K10907 - - 0.00000000000000000000000000000000000000000000000000000000001213 221.0
HFD3_k127_1052517_3 COG1388 FOG LysM repeat K19223,K19224 - - 0.0000000000001341 79.0
HFD3_k127_1052517_4 Peptidase propeptide and YPEB domain - - - 0.0002091 50.0
HFD3_k127_1057890_0 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 608.0
HFD3_k127_1057890_1 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 412.0
HFD3_k127_1057890_2 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000253 191.0
HFD3_k127_1057890_3 Winged helix DNA-binding domain - - - 0.0000000000000000000000000000000000000829 146.0
HFD3_k127_1057890_4 - - - - 0.000000000000000002321 94.0
HFD3_k127_1057890_5 - - - - 0.00000000000003303 75.0
HFD3_k127_1081060_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 500.0
HFD3_k127_1081060_1 LAO AO transport system K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003629 266.0
HFD3_k127_1081060_10 arsenate reductase (glutaredoxin) activity K00537 - 1.20.4.1 0.00000000000000000001405 94.0
HFD3_k127_1081060_2 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000002514 260.0
HFD3_k127_1081060_3 CoA binding domain K06929 - - 0.000000000000000000000000000000000000000000000000000000913 195.0
HFD3_k127_1081060_4 Uncharacterized protein conserved in bacteria (DUF2237) - - - 0.0000000000000000000000000000000000000000000000000002233 188.0
HFD3_k127_1081060_5 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000002004 182.0
HFD3_k127_1081060_6 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000006794 184.0
HFD3_k127_1081060_7 DinB family - - - 0.000000000000000000000000000000000000000000000007861 177.0
HFD3_k127_1081060_8 PFAM DinB - - - 0.000000000000000000000000000000000000002049 152.0
HFD3_k127_1081060_9 DinB family - - - 0.0000000000000000000002274 103.0
HFD3_k127_1104297_0 SpoIVB peptidase S55 - - - 0.0000000000000000000000000000000000000000000000000000002055 205.0
HFD3_k127_1104297_1 X-Pro dipeptidyl-peptidase (S15 family) K06889 - - 0.00000000006502 74.0
HFD3_k127_1104297_2 ATP-dependent protease La (LON) domain K01338 - 3.4.21.53 0.00000004619 60.0
HFD3_k127_1105587_0 Isocitrate dehydrogenase K00031 - 1.1.1.42 0.0 1228.0
HFD3_k127_1105587_1 - K00262 - 1.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003528 386.0
HFD3_k127_1105587_10 ADP-ribosylglycohydrolase K05521 - 3.2.2.24 0.000000000000000000989 89.0
HFD3_k127_1105587_2 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000006772 253.0
HFD3_k127_1105587_3 DNA alkylation repair enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000002724 241.0
HFD3_k127_1105587_4 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000001151 228.0
HFD3_k127_1105587_5 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.00000000000000000000000000000000000000000000004962 173.0
HFD3_k127_1105587_6 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000000000000000003022 168.0
HFD3_k127_1105587_7 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.00000000000000000000000001267 115.0
HFD3_k127_1105587_8 Thioredoxin-like - - - 0.0000000000000000000002279 106.0
HFD3_k127_1105587_9 Transcriptional coactivator pterin dehydratase K01724 - 4.2.1.96 0.00000000000000000001614 93.0
HFD3_k127_1157847_0 beta-lactamase - - - 5.581e-241 771.0
HFD3_k127_1157847_1 Carboxypeptidase regulatory-like domain - - - 1.876e-238 781.0
HFD3_k127_1157847_10 LysR substrate binding domain K21703,K21711 - - 0.0000000000000000000000000000000000001639 153.0
HFD3_k127_1157847_11 TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED K01091,K01838 - 3.1.3.18,5.4.2.6 0.0000000000000001438 86.0
HFD3_k127_1157847_12 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.0000000000001964 74.0
HFD3_k127_1157847_13 Tetratricopeptide repeat K20543 - - 0.00000001011 68.0
HFD3_k127_1157847_2 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000824 424.0
HFD3_k127_1157847_3 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 387.0
HFD3_k127_1157847_4 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004968 359.0
HFD3_k127_1157847_5 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 300.0
HFD3_k127_1157847_6 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 297.0
HFD3_k127_1157847_7 PFAM TonB-dependent Receptor Plug - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003615 305.0
HFD3_k127_1157847_8 Predicted membrane protein (DUF2231) - - - 0.000000000000000000000000000000000000000000000000000005011 194.0
HFD3_k127_1157847_9 BadF/BadG/BcrA/BcrD ATPase family - GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006040,GO:0006044,GO:0006082,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0045127,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901071,GO:1901135,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000001336 154.0
HFD3_k127_1161054_0 with different specificities (Related to short-chain alcohol - - - 0.000000000000000000000000000000000000000000000000000222 189.0
HFD3_k127_1161054_1 SpoU rRNA Methylase family K03216 - 2.1.1.207 0.000000000000000000000000000000000000000000000000109 184.0
HFD3_k127_1161054_2 BON domain - - - 0.0000000000000000000000000000731 122.0
HFD3_k127_1161054_3 - - - - 0.000000000005207 74.0
HFD3_k127_1187510_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 453.0
HFD3_k127_1187510_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005843 339.0
HFD3_k127_1193896_0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000001147 241.0
HFD3_k127_1193896_1 Periplasmic or secreted lipoprotein - - - 0.000000000000001814 86.0
HFD3_k127_1193896_2 DSHCT - - - 0.0000000000001909 80.0
HFD3_k127_1194078_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 482.0
HFD3_k127_1194078_1 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001412 273.0
HFD3_k127_1194078_10 Psort location Cytoplasmic, score 8.87 K06960 - - 0.0000000000000002256 81.0
HFD3_k127_1194078_11 SMART Transport-associated and nodulation region K04065 - - 0.000005398 56.0
HFD3_k127_1194078_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000001168 205.0
HFD3_k127_1194078_3 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.000000000000000000000000000000000000000000884 160.0
HFD3_k127_1194078_4 Beta-lactamase - - - 0.00000000000000000000000000000001102 135.0
HFD3_k127_1194078_5 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000003854 119.0
HFD3_k127_1194078_6 Beta-lactamase - - - 0.00000000000000000000002995 101.0
HFD3_k127_1194078_7 Glycosyltransferase family 9 (heptosyltransferase) K02849 - - 0.0000000000000000000006068 104.0
HFD3_k127_1194078_8 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000000000000001285 99.0
HFD3_k127_1194078_9 - - - - 0.0000000000000002066 85.0
HFD3_k127_1195892_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 6.601e-295 925.0
HFD3_k127_1195892_1 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000000000000003952 212.0
HFD3_k127_1195892_2 RNA polymerase sigma factor K03088 - - 0.000000000000000000000000000000000000000000003446 171.0
HFD3_k127_1195892_3 Peptidase, M23 family - - - 0.000000000000000000000000000000000000000366 159.0
HFD3_k127_1195892_4 - - - - 0.00000000000006001 81.0
HFD3_k127_1195892_5 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000005771 81.0
HFD3_k127_1199143_0 Metalloenzyme superfamily K01839 - 5.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 443.0
HFD3_k127_1199143_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409,K03070 GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005489 351.0
HFD3_k127_1199143_2 glucose sorbosone - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009874 323.0
HFD3_k127_1199143_3 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000004697 259.0
HFD3_k127_1199143_4 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000004837 175.0
HFD3_k127_1199143_5 - - - - 0.000000000000000000000000000000495 126.0
HFD3_k127_1199143_6 Competence protein - - - 0.000000000000000000000008863 110.0
HFD3_k127_1205956_0 Major facilitator Superfamily - - - 0.00000000000000000000000000000000001317 144.0
HFD3_k127_1205956_1 PFAM DnaJ homologue, subfamily C, member 28, conserved domain - - - 0.000000000000000000000000003116 115.0
HFD3_k127_1205956_2 Glyoxalase-like domain - - - 0.00000000000004291 76.0
HFD3_k127_1217219_0 Radical SAM - - - 2.193e-303 943.0
HFD3_k127_1217219_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 474.0
HFD3_k127_1218858_0 phosphoesterase, PA-phosphatase related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004124 333.0
HFD3_k127_1218858_1 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000000000007348 204.0
HFD3_k127_1218858_2 Lactonase, 7-bladed beta-propeller - - - 0.0000000000003188 78.0
HFD3_k127_1218858_3 Protein tyrosine kinase K08884,K12132 - 2.7.11.1 0.0002543 44.0
HFD3_k127_1219416_0 Dienelactone hydrolase family - - - 8.934e-275 869.0
HFD3_k127_1219416_1 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007995 349.0
HFD3_k127_1219416_2 Glycosyl hydrolase family 47 K01230 - 3.2.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007945 321.0
HFD3_k127_1219416_3 epimerase dehydratase K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 291.0
HFD3_k127_1219416_4 Beta-lactamase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000007578 235.0
HFD3_k127_1219416_5 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000000001073 166.0
HFD3_k127_122950_0 Tricorn protease homolog K08676 - - 3.808e-243 764.0
HFD3_k127_122950_1 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 415.0
HFD3_k127_122950_2 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003454 300.0
HFD3_k127_122950_3 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000004191 233.0
HFD3_k127_122950_4 Sigma-54 dependent response regulator K07714 - - 0.0000000000000000000002867 99.0
HFD3_k127_122950_5 PFAM Adenylate cyclase K05873 - 4.6.1.1 0.00000000000000000003285 97.0
HFD3_k127_122950_6 Receptor - - - 0.00001492 55.0
HFD3_k127_1245342_0 PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 375.0
HFD3_k127_1245342_1 Lecithin:cholesterol acyltransferase - - - 0.00000000000000000000000000000000004063 147.0
HFD3_k127_126091_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007509 390.0
HFD3_k127_126091_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 310.0
HFD3_k127_126091_2 Belongs to the ATCase OTCase family K09065 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0043857,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 300.0
HFD3_k127_126091_3 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000005161 258.0
HFD3_k127_126091_4 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000003179 192.0
HFD3_k127_126091_5 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145,K05829 - 1.2.1.38 0.000000000000000000000000000000000000005608 150.0
HFD3_k127_126091_6 Preprotein translocase SecG subunit K03075 - - 0.0000002583 58.0
HFD3_k127_1268681_0 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006515 582.0
HFD3_k127_1268681_1 PD-(D/E)XK nuclease superfamily K16898 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000938 539.0
HFD3_k127_1268681_10 Phage portal protein, SPP1 Gp6-like - - - 0.00000000000000000000000000000000000000000000005474 186.0
HFD3_k127_1268681_11 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000002242 161.0
HFD3_k127_1268681_12 - - - - 0.00000000000000000005067 99.0
HFD3_k127_1268681_13 von Willebrand factor (vWF) type A domain K07114 - - 0.000000000000001433 88.0
HFD3_k127_1268681_2 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 528.0
HFD3_k127_1268681_3 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006379 493.0
HFD3_k127_1268681_4 P22 coat protein-protein 5 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 353.0
HFD3_k127_1268681_5 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 299.0
HFD3_k127_1268681_6 DJ-1/PfpI family K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000648 282.0
HFD3_k127_1268681_7 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000127 254.0
HFD3_k127_1268681_8 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001324 263.0
HFD3_k127_1268681_9 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000002003 222.0
HFD3_k127_1273952_0 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840,K15778 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000008384 200.0
HFD3_k127_1273952_1 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000002204 180.0
HFD3_k127_1273952_2 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000000000000000245 184.0
HFD3_k127_1273952_3 PFAM von Willebrand factor type A - - - 0.00000000000000000000000000000000000000547 159.0
HFD3_k127_1273952_4 alpha-ribazole phosphatase activity K01834 - 5.4.2.11 0.0000000557 56.0
HFD3_k127_1323805_0 peptidase activity K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003515 282.0
HFD3_k127_1323805_1 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008831,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019305,GO:0019438,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901576 1.1.1.133 0.00000000000000000000000000000000000000000000000001403 190.0
HFD3_k127_1323805_2 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000392 189.0
HFD3_k127_1335097_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 4.449e-208 667.0
HFD3_k127_1335097_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000809 555.0
HFD3_k127_1335097_10 PFAM D12 class N6 adenine-specific DNA methyltransferase K07318 - 2.1.1.72 0.00002341 55.0
HFD3_k127_1335097_2 Ring hydroxylating alpha subunit (catalytic domain) K00499 - 1.14.15.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003123 355.0
HFD3_k127_1335097_3 PFAM Alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000438 250.0
HFD3_k127_1335097_4 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000008752 166.0
HFD3_k127_1335097_5 acetyltransferase K03828 - - 0.0000000000000000000000000000000000002473 147.0
HFD3_k127_1335097_6 PFAM HD domain - - - 0.0000000000000000000000000000001034 133.0
HFD3_k127_1335097_7 Response regulator, receiver - - - 0.000001257 61.0
HFD3_k127_1335097_8 heat shock protein binding K03686,K05801,K17867 - - 0.000001662 61.0
HFD3_k127_1335097_9 Transmembrane secretion effector K18215 - - 0.000004342 55.0
HFD3_k127_136411_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004194 420.0
HFD3_k127_136411_1 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000001596 168.0
HFD3_k127_136411_2 EamA-like transporter family K07790 - - 0.000000000000000000000000000000000000000000163 170.0
HFD3_k127_136411_3 Conserved hypothetical protein 95 - - - 0.0000000000000000000000000000000000004809 146.0
HFD3_k127_136411_4 TIGRFAM RNA methyltransferase, RsmD family - - - 0.0002197 47.0
HFD3_k127_1372915_0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K07516 - 1.1.1.35 7.298e-257 816.0
HFD3_k127_1372915_1 Peptidase S9 prolyl oligopeptidase active site - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 526.0
HFD3_k127_1372915_2 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006598 297.0
HFD3_k127_1372915_3 Pkd domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000008355 243.0
HFD3_k127_1372915_4 Calcium/calmodulin dependent protein kinase II association domain - - - 0.00000000000000000000000000000000000002561 147.0
HFD3_k127_1372915_5 Methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000004569 116.0
HFD3_k127_1372915_6 DinB superfamily - - - 0.0000000000000000000000000005499 121.0
HFD3_k127_1372915_8 Putative peptidoglycan binding domain - - - 0.00003674 54.0
HFD3_k127_1374038_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008029 407.0
HFD3_k127_1374038_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 410.0
HFD3_k127_1374038_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 368.0
HFD3_k127_1374038_3 cell redox homeostasis K16089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009128 293.0
HFD3_k127_1374038_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000006802 241.0
HFD3_k127_1374038_5 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000001052 180.0
HFD3_k127_1374038_6 Preprotein translocase, YajC subunit K03210 - - 0.00000000000003244 76.0
HFD3_k127_1388070_0 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 356.0
HFD3_k127_1388070_1 PFAM Binding-protein-dependent transport system inner membrane component K02033,K15581,K15585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004431 327.0
HFD3_k127_1388070_2 'ABC-type dipeptide oligopeptide nickel transport K02034,K15582 - - 0.00000000000000000000000000000000000000002497 160.0
HFD3_k127_1388070_3 ABC-type oligopeptide transport system, periplasmic component K15580 - - 0.00000000000000000000001977 109.0
HFD3_k127_1391668_0 SMART tyrosine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 300.0
HFD3_k127_1391668_1 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.00000000000000000000000000000000000000000003374 165.0
HFD3_k127_1391668_2 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000000001499 91.0
HFD3_k127_1393823_0 AIR carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003315 278.0
HFD3_k127_1393823_1 COG0457 FOG TPR repeat - - - 0.00000000000000000001884 98.0
HFD3_k127_1393823_2 prenyltransferase activity K03186 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0044237,GO:0044249,GO:0051186,GO:0051188 2.5.1.129 0.00000000000000002931 86.0
HFD3_k127_1409481_0 RecF RecN SMC N terminal domain K03546 - - 0.0000000000000000000000000000000000000000000000002847 191.0
HFD3_k127_1409481_1 - - - - 0.00000000008326 66.0
HFD3_k127_1409481_2 Putative adhesin - - - 0.000001218 60.0
HFD3_k127_1429030_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000758 302.0
HFD3_k127_1429030_1 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000003541 125.0
HFD3_k127_1429030_2 AAA domain - - - 0.00000000000002243 78.0
HFD3_k127_1441627_0 WD40 domain protein beta Propeller K12132 - 2.7.11.1 1.892e-221 717.0
HFD3_k127_1441627_1 Universal stress protein family - - - 0.00000000000007486 74.0
HFD3_k127_1442314_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008074 439.0
HFD3_k127_1442314_1 Protein of unknown function, DUF393 - - - 0.00000000000000000000000000000002152 129.0
HFD3_k127_1449304_0 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004036 445.0
HFD3_k127_1449304_1 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000001401 211.0
HFD3_k127_1449304_2 - - - - 0.0002844 47.0
HFD3_k127_1482330_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003237 274.0
HFD3_k127_1482330_1 Bacterial DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000001989 248.0
HFD3_k127_1522176_0 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002065 286.0
HFD3_k127_1522176_1 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000000000007789 203.0
HFD3_k127_1522176_2 WD40-like Beta Propeller Repeat K03641 - - 0.00000000000000000000000000000000000000000000369 177.0
HFD3_k127_1522176_3 - - - - 0.000000000000007779 86.0
HFD3_k127_1551927_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1113.0
HFD3_k127_1551927_1 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000028 503.0
HFD3_k127_1551927_2 Belongs to the ClpA ClpB family K03695,K03696 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 399.0
HFD3_k127_1551927_3 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005246 302.0
HFD3_k127_1551927_4 PFAM Branched-chain amino acid transport system permease component K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 295.0
HFD3_k127_1551927_5 PFAM Branched-chain amino acid transport system permease component K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 300.0
HFD3_k127_1551927_6 Cytidine monophosphokinase K00876 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 0.00000000000000000000000000000000000000000000000000000000000000009927 228.0
HFD3_k127_1551927_7 Cytidine and deoxycytidylate deaminase zinc-binding region K01489 - 3.5.4.5 0.00000000000000000000000000000000000000000001827 165.0
HFD3_k127_1551927_8 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000312 154.0
HFD3_k127_1551927_9 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000002619 93.0
HFD3_k127_1554171_0 Type IV pilus assembly protein PilM; K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000636 299.0
HFD3_k127_1554171_1 type IV pilus secretin PilQ K02507,K02666 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000005015 241.0
HFD3_k127_1554171_2 FR47-like protein K03823 - 2.3.1.183 0.0000000000000000000000000000000000000000000002702 171.0
HFD3_k127_1554171_3 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000009727 62.0
HFD3_k127_1554171_4 Belongs to the glycosyl hydrolase 32 family K00692 - 2.4.1.10 0.000000003855 59.0
HFD3_k127_1554171_5 Pilus assembly protein, PilO K02664 - - 0.000000005429 65.0
HFD3_k127_1554171_6 PFAM Fimbrial assembly family protein K02663 - - 0.0004171 51.0
HFD3_k127_1565650_0 Protein of unknown function (DUF2752) - - - 0.00000000000002628 76.0
HFD3_k127_1565650_1 TIGRFAM TonB K03832 - - 0.0000168 55.0
HFD3_k127_1569099_0 Protein of unknown function, DUF255 K06888 - - 4.208e-231 735.0
HFD3_k127_1569099_1 Beta-Casp domain K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 465.0
HFD3_k127_1569099_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000003232 125.0
HFD3_k127_1571948_0 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 362.0
HFD3_k127_1571948_1 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000002684 144.0
HFD3_k127_1571948_2 Nodulation protein S (NodS) - - - 0.000000000000000000000001299 108.0
HFD3_k127_1571948_3 AdoMet dependent proline di-methyltransferase - - - 0.00000000000000000003204 91.0
HFD3_k127_1594934_0 Mur ligase family, glutamate ligase domain K03802 - 6.3.2.29,6.3.2.30 2.134e-321 1006.0
HFD3_k127_1594934_1 TIGRFAM carbamoyl-phosphate synthase, large subunit K01955 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000869 373.0
HFD3_k127_1594934_2 Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin K13282 - 3.4.15.6 0.000000000000000000000000000000000000000000000000000000000000000000007732 243.0
HFD3_k127_1594934_3 Phosphotransferase enzyme family K17880 - 2.7.1.119 0.0000000000000000001346 100.0
HFD3_k127_1598612_0 Thioredoxin reductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008393 312.0
HFD3_k127_1598612_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000005707 261.0
HFD3_k127_1598612_2 Lipocalin / cytosolic fatty-acid binding protein family K03098 - - 0.0000000000000000000000000000000000000000000000000000002785 198.0
HFD3_k127_1598612_3 OmpA family - - - 0.0000000000000000000000002806 119.0
HFD3_k127_1598612_4 Putative regulatory protein - - - 0.0000000000000000002219 91.0
HFD3_k127_1598612_5 TIGRFAM VWFA-related Acidobacterial domain - - - 0.000000001397 69.0
HFD3_k127_1600178_0 Pyridine nucleotide-disulphide oxidoreductase - - - 1.78e-312 983.0
HFD3_k127_1600178_1 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008327 415.0
HFD3_k127_1600178_2 G-rich domain on putative tyrosine kinase K16554 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002602 276.0
HFD3_k127_1600178_3 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000009079 214.0
HFD3_k127_1600178_4 Bacterial PH domain - - - 0.000357 50.0
HFD3_k127_1605085_0 cAMP biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001675 267.0
HFD3_k127_1605085_1 Hemolysin-type calcium-binding repeat (2 copies) - - - 0.00000000000000000000000000000000000000000000000000000000000000003525 242.0
HFD3_k127_1605085_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000001232 230.0
HFD3_k127_1605085_3 cAMP biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000004504 195.0
HFD3_k127_1607479_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 3.863e-284 895.0
HFD3_k127_1607479_1 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000008235 209.0
HFD3_k127_1618626_0 Beta-eliminating lyase K01668 - 4.1.99.2 5.29e-234 732.0
HFD3_k127_1618626_1 DAHP synthetase I family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009164 572.0
HFD3_k127_1618626_10 outer membrane chaperone Skp (OmpH) K06142 - - 0.0001326 51.0
HFD3_k127_1618626_2 TIGRFAM outer membrane protein assembly complex, YaeT protein K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 458.0
HFD3_k127_1618626_3 von Willebrand factor (vWF) type A domain K02448 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000778 349.0
HFD3_k127_1618626_4 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0008780,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000311 278.0
HFD3_k127_1618626_5 amino acid-binding ACT domain protein K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000001621 215.0
HFD3_k127_1618626_6 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000008919 172.0
HFD3_k127_1618626_7 Transposase (IS116 IS110 IS902 family) - - - 0.000000000000000000000000000002702 123.0
HFD3_k127_1618626_8 - - - - 0.000000001036 63.0
HFD3_k127_1618626_9 Type II IV secretion system protein K02283,K03609 - - 0.00006005 55.0
HFD3_k127_1619546_0 Glycogen debranching enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002565 277.0
HFD3_k127_1619546_1 glycoside hydrolase family 38 K01191 - 3.2.1.24 0.000000000002677 80.0
HFD3_k127_1623498_0 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 285.0
HFD3_k127_1623498_1 Belongs to the PEP-utilizing enzyme family K01006,K01007 - 2.7.9.1,2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000479 278.0
HFD3_k127_1623498_2 UDP-glucoronosyl and UDP-glucosyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000001021 224.0
HFD3_k127_1628962_0 Protein tyrosine kinase - - - 5.556e-205 668.0
HFD3_k127_1628962_1 MgtE intracellular N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001978 242.0
HFD3_k127_1628962_2 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000731 122.0
HFD3_k127_1649774_0 cystathionine gamma-synthase activity K01739,K01740,K01758,K01760,K01761 - 2.5.1.48,2.5.1.49,4.4.1.1,4.4.1.11,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 588.0
HFD3_k127_1649774_1 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 582.0
HFD3_k127_1649774_2 COG0491 Zn-dependent K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 414.0
HFD3_k127_1649774_3 PAAR motif - - - 0.000000000000000000000000000000000000000000000000000000000000001636 222.0
HFD3_k127_1649774_4 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000003408 152.0
HFD3_k127_1649774_5 rhodanese - - - 0.0000000000000000000726 96.0
HFD3_k127_165277_0 tRNA nucleotidyltransferase poly(A) polymerase K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 368.0
HFD3_k127_165277_1 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006117 297.0
HFD3_k127_165277_2 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000006516 217.0
HFD3_k127_165277_3 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000002759 218.0
HFD3_k127_165277_4 Involved in the tonB-independent uptake of proteins K03641 - - 0.00000000000000000000000000000000000000000000002384 189.0
HFD3_k127_165277_5 Formiminotransferase domain, N-terminal subdomain K00603,K13990 - 2.1.2.5,4.3.1.4 0.00000000000000000000000001027 111.0
HFD3_k127_165277_6 Peptidase family M23 - - - 0.0000000000000000000002321 102.0
HFD3_k127_1663892_0 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007242 602.0
HFD3_k127_1663892_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 394.0
HFD3_k127_1663892_2 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006698 364.0
HFD3_k127_1663892_3 PFAM ATP-binding region, ATPase domain protein K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000003616 253.0
HFD3_k127_1663892_4 Two component transcriptional regulator, winged helix family K07658,K07668 - - 0.00000000000000000000000000000000000000000000000000000000000361 215.0
HFD3_k127_1670214_0 Carboxypeptidase regulatory-like domain - - - 1.219e-307 973.0
HFD3_k127_1670214_1 - - - - 0.000000000000000000000000000000000000000000000001153 179.0
HFD3_k127_1670214_2 Chloramphenicol acetyltransferase K19271 - 2.3.1.28 0.00000000000000000000000000000000000000000003785 169.0
HFD3_k127_1670214_3 DoxX family - - - 0.0000000000000002153 81.0
HFD3_k127_1670214_4 - - - - 0.0000000000000002845 88.0
HFD3_k127_1680761_0 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000297 197.0
HFD3_k127_1680761_1 COGs COG2905 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.000000000000000000000000000000000000000000168 164.0
HFD3_k127_1680761_2 Iron-sulphur cluster biosynthesis - - - 0.000000000000000000000000000000000001094 141.0
HFD3_k127_1680761_3 Lipoprotein - - - 0.0000000000000000000000000000000002114 146.0
HFD3_k127_1680761_4 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.0000000000000000000000000000125 132.0
HFD3_k127_1680761_5 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000029 55.0
HFD3_k127_168671_0 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 437.0
HFD3_k127_168671_1 Rifampin ADP-ribosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007154 403.0
HFD3_k127_168671_10 Transposase K07491 - - 0.00000000001052 66.0
HFD3_k127_168671_11 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000001237 66.0
HFD3_k127_168671_2 dihydrofolate reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000231 261.0
HFD3_k127_168671_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002576 245.0
HFD3_k127_168671_4 Activator of Hsp90 ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001129 245.0
HFD3_k127_168671_5 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000000000000000000000000000000002225 226.0
HFD3_k127_168671_6 PFAM Bacterial regulatory protein, arsR family - - - 0.000000000000000000000000000000000000000000000000003177 183.0
HFD3_k127_168671_7 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000004982 148.0
HFD3_k127_168671_8 light absorption - - - 0.000000000000000000002641 96.0
HFD3_k127_168671_9 DinB family - - - 0.00000000000002585 79.0
HFD3_k127_169076_0 transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 329.0
HFD3_k127_169076_1 40-residue YVTN family beta-propeller repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008911 310.0
HFD3_k127_169076_2 Putative esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001399 258.0
HFD3_k127_169076_3 Belongs to the UPF0235 family K09131 - - 0.0000000000000166 76.0
HFD3_k127_1712625_0 PFAM Type II secretion system protein E K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005284 566.0
HFD3_k127_1712625_1 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01751,K01754,K06016,K17989 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008838,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.5.1.6,3.5.1.87,4.3.1.15,4.3.1.17,4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 351.0
HFD3_k127_1712625_2 von Willebrand factor (vWF) type A domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000162 247.0
HFD3_k127_1712625_3 Type II secretion system (T2SS), protein F K02455,K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000002375 247.0
HFD3_k127_1712625_4 von Willebrand factor, type A - - - 0.00000000000000000000000000000000001056 150.0
HFD3_k127_1712625_5 PFAM Type II secretion system protein E K02652 - - 0.000000000000000000000000004112 118.0
HFD3_k127_1712625_6 PFAM aminoglycoside hydroxyurea antibiotic resistance kinase K04343 - 2.7.1.72 0.00000000000415 70.0
HFD3_k127_1734151_0 Peptidase M14, carboxypeptidase A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 591.0
HFD3_k127_1734151_1 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003369 283.0
HFD3_k127_1749390_0 Peptidase M1, membrane alanine aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009612 360.0
HFD3_k127_1749390_1 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000005356 189.0
HFD3_k127_1749390_2 amidohydrolase - - - 0.0005261 46.0
HFD3_k127_1761718_0 Arylsulfatase a K01133 - 3.1.6.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 400.0
HFD3_k127_1761718_1 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 401.0
HFD3_k127_1761718_10 - - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0000003431 59.0
HFD3_k127_1761718_2 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000569 265.0
HFD3_k127_1761718_3 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000003026 196.0
HFD3_k127_1761718_4 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000000000000000000000000004992 173.0
HFD3_k127_1761718_5 PFAM Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000008977 111.0
HFD3_k127_1761718_6 Sulfatase - - - 0.000000000000002292 79.0
HFD3_k127_1761718_7 transport - - - 0.000000000214 73.0
HFD3_k127_1761718_8 - - - - 0.00000001456 67.0
HFD3_k127_1761718_9 Ankyrin repeat and SOCS box protein 3 K10325 GO:0000151,GO:0003674,GO:0003824,GO:0004842,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016567,GO:0016740,GO:0019538,GO:0019787,GO:0019899,GO:0031625,GO:0032446,GO:0032991,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044389,GO:0044424,GO:0044444,GO:0044464,GO:0070647,GO:0071704,GO:0140096,GO:1901564,GO:1902494,GO:1990234 - 0.00000002553 66.0
HFD3_k127_1767631_0 Prolyl oligopeptidase, N-terminal beta-propeller domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005755 533.0
HFD3_k127_1771988_0 Involved in the biosynthesis of porphyrin-containing compound - GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004993 300.0
HFD3_k127_1771988_1 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000000000000000000000001134 163.0
HFD3_k127_1783509_0 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005176 392.0
HFD3_k127_1783509_1 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000003078 251.0
HFD3_k127_1783509_2 Domain of unknown function (DUF4440) - - - 0.00000000000000001681 93.0
HFD3_k127_1795059_0 Glycosyl hydrolase family 1 - - - 7.383e-216 676.0
HFD3_k127_1795059_1 Glycine D-amino acid oxidase (deaminating) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 503.0
HFD3_k127_1795059_10 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000000000000001087 163.0
HFD3_k127_1795059_11 Protein of unknown function (DUF4242) - - - 0.000000000000000000000000000000000513 132.0
HFD3_k127_1795059_12 Fumarate reductase flavoprotein C-term K00239 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0022900,GO:0044237,GO:0045333,GO:0055114 1.3.5.1,1.3.5.4 0.000000000000000039 81.0
HFD3_k127_1795059_13 - - - - 0.00000000000003564 78.0
HFD3_k127_1795059_14 Penicillin amidase K07116 - 3.5.1.97 0.0000006809 61.0
HFD3_k127_1795059_15 STAS domain - - - 0.0005734 46.0
HFD3_k127_1795059_2 antibiotic biosynthetic process K01434,K07116 - 3.5.1.11,3.5.1.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005471 375.0
HFD3_k127_1795059_3 Zinc metalloprotease (Elastase) K20274 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009998 352.0
HFD3_k127_1795059_4 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 298.0
HFD3_k127_1795059_5 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001287 254.0
HFD3_k127_1795059_6 Transcriptional regulator K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002444 270.0
HFD3_k127_1795059_7 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000000000000000000000000003302 200.0
HFD3_k127_1795059_8 HD domain - - - 0.000000000000000000000000000000000000000000000000004071 198.0
HFD3_k127_1795059_9 TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family K00241 - - 0.00000000000000000000000000000000000000000001342 170.0
HFD3_k127_1800493_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 4.515e-274 866.0
HFD3_k127_1800493_1 Hsp20/alpha crystallin family K13993 - - 0.0000000000000000001077 93.0
HFD3_k127_1800493_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.00001221 48.0
HFD3_k127_1800493_3 TPR repeat-containing protein - - - 0.00002938 53.0
HFD3_k127_180394_0 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005853 294.0
HFD3_k127_180394_1 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000000000003486 207.0
HFD3_k127_180394_2 PFAM O-methyltransferase - - - 0.00000000000000000000000000000000000000000002981 168.0
HFD3_k127_1814240_0 Cytochrome c biogenesis protein transmembrane region K04084 - 1.8.1.8 0.00000000000000000000000000000000000000000006277 168.0
HFD3_k127_1814240_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000001249 119.0
HFD3_k127_1814240_2 Thioredoxin - - - 0.00000000000000002282 87.0
HFD3_k127_1846757_0 Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate K00451 - 1.13.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008677 406.0
HFD3_k127_1846757_1 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005668 360.0
HFD3_k127_1846757_2 histone H4-K16 acetylation K07020 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 291.0
HFD3_k127_1846757_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000001314 148.0
HFD3_k127_1846757_4 Uncharacterized conserved protein (DUF2277) - - - 0.00000000000000000000000000000009207 125.0
HFD3_k127_1846757_5 glycolate biosynthetic process K01091,K06019,K13292 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.1.3.18,3.6.1.1 0.000000000000000000000000003896 117.0
HFD3_k127_1853155_0 Protein of unknown function (DUF1800) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 389.0
HFD3_k127_1853155_1 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005159 321.0
HFD3_k127_1853155_2 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000005522 214.0
HFD3_k127_1853155_3 membrane protein, TerC K05794 - - 0.0000000000000000000000000000000000004863 142.0
HFD3_k127_1853155_4 RibD C-terminal domain K11752 - 1.1.1.193,3.5.4.26 0.0000000000003505 70.0
HFD3_k127_1876746_0 Belongs to the glycosyl hydrolase 31 family - - - 4.777e-265 835.0
HFD3_k127_1876746_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0000000000005062 70.0
HFD3_k127_1878310_0 Penicillin amidase K01434 - 3.5.1.11 0.0 1028.0
HFD3_k127_1878310_1 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 387.0
HFD3_k127_1878310_2 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000124 253.0
HFD3_k127_1878310_3 Domain of unknown function (DUF2383) - - - 0.000000000000000000000000000000000000000000002636 170.0
HFD3_k127_1878310_4 Domain of unknown function (DUF4440) - - - 0.000000000000000000000000000001912 126.0
HFD3_k127_1878310_5 sigma factor antagonist activity K04757 - 2.7.11.1 0.00000000000483 79.0
HFD3_k127_189519_0 Orotidine 5'-phosphate decarboxylase / HUMPS family K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000691 239.0
HFD3_k127_189519_1 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0000000000000000000000000000000000000000000000001215 181.0
HFD3_k127_189519_2 iron ion homeostasis K04758 - - 0.0000000000000001978 81.0
HFD3_k127_189519_3 Protein of unknown function (DUF3108) - - - 0.0002797 53.0
HFD3_k127_1903204_0 Catalyzes the synthesis of activated sulfate K00958 - 2.7.7.4 3.367e-220 697.0
HFD3_k127_1903204_1 Sulfotransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000005253 230.0
HFD3_k127_1903204_2 dextransucrase activity - - - 0.00000000000000000000000000000000000000000000000000000000004454 224.0
HFD3_k127_1903204_3 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.00000418 49.0
HFD3_k127_190613_0 PEP-utilising enzyme, N-terminal K08483 - 2.7.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 357.0
HFD3_k127_190613_1 Mitochondrial biogenesis AIM24 - - - 0.000000000000000000000000000000000000000000000000000000000000000269 224.0
HFD3_k127_190613_2 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000005191 228.0
HFD3_k127_190613_3 Tetratricopeptide repeat - - - 0.00005417 53.0
HFD3_k127_1911581_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 1.238e-274 863.0
HFD3_k127_1911581_1 nitrite transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006682 288.0
HFD3_k127_1911581_2 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001223 234.0
HFD3_k127_1911581_3 Domain of Unknown function (DUF542) K07322 - - 0.000000000000000000000000000000000000000000000000000000000000321 219.0
HFD3_k127_1911581_4 YwiC-like protein - - - 0.000000000000000000005283 98.0
HFD3_k127_1911581_5 - - - - 0.00000000000000001823 88.0
HFD3_k127_1914169_0 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006446 406.0
HFD3_k127_1914169_1 COG1078 HD superfamily phosphohydrolases K06885 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005242 297.0
HFD3_k127_1914169_2 Tetratricopeptide repeat - - - 0.0002845 52.0
HFD3_k127_1915430_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 398.0
HFD3_k127_1915430_1 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000001079 247.0
HFD3_k127_1915430_2 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000003417 158.0
HFD3_k127_192710_0 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000002669 238.0
HFD3_k127_192710_1 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 0.0000000000000000000000000000000000000000000285 162.0
HFD3_k127_1938297_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 9.827e-225 705.0
HFD3_k127_1938297_1 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases K00174 - 1.2.7.11,1.2.7.3 2.626e-223 709.0
HFD3_k127_1938297_2 PFAM Mannosyl oligosaccharide glucosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 600.0
HFD3_k127_1938297_3 alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 497.0
HFD3_k127_1938297_4 2 iron, 2 sulfur cluster binding K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 463.0
HFD3_k127_1938297_5 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 358.0
HFD3_k127_1938297_6 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000005119 251.0
HFD3_k127_1938297_7 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000006793 206.0
HFD3_k127_1938297_8 mannose-1-phosphate guanylyltransferase activity K00971,K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000000002297 190.0
HFD3_k127_1945499_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 574.0
HFD3_k127_1945499_1 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004762 457.0
HFD3_k127_1945499_10 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000003646 139.0
HFD3_k127_1945499_11 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000817 54.0
HFD3_k127_1945499_12 Tetratricopeptide repeat - - - 0.000003531 59.0
HFD3_k127_1945499_13 Pkd domain containing protein - - - 0.0008327 53.0
HFD3_k127_1945499_2 Glycine cleavage system P-protein K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 456.0
HFD3_k127_1945499_3 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004873 402.0
HFD3_k127_1945499_4 Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005182 323.0
HFD3_k127_1945499_5 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003481 276.0
HFD3_k127_1945499_6 PFAM PP-loop domain protein K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000631 255.0
HFD3_k127_1945499_7 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000000004123 172.0
HFD3_k127_1945499_8 Belongs to the BshC family K22136 - - 0.000000000000000000000000000000000000000002601 167.0
HFD3_k127_1945499_9 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.000000000000000000000000000000000000000008433 157.0
HFD3_k127_1960150_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 418.0
HFD3_k127_1960150_1 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003449 246.0
HFD3_k127_1960150_2 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000000002726 150.0
HFD3_k127_1960150_3 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.0000000000000000000000000000007475 127.0
HFD3_k127_1960150_4 Polymer-forming cytoskeletal - - - 0.00000000000000001095 92.0
HFD3_k127_1960150_5 - - - - 0.0000000000000004269 90.0
HFD3_k127_1980224_0 TIGRFAM methylmalonate-semialdehyde dehydrogenase K00140,K22187 - 1.2.1.18,1.2.1.27 2.25e-234 733.0
HFD3_k127_1980224_1 PFAM Permease for cytosine purines, uracil, thiamine, allantoin K03457 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007979 574.0
HFD3_k127_1980224_2 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01431 - 3.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 485.0
HFD3_k127_1980224_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000565 357.0
HFD3_k127_1980224_4 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007383 315.0
HFD3_k127_1980224_5 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000001824 170.0
HFD3_k127_1980224_6 Glutamate synthase K17722 - 1.3.1.1 0.0000000000000000000000000000000000000004829 151.0
HFD3_k127_1980224_7 Lysylphosphatidylglycerol synthase TM region - - - 0.000001485 52.0
HFD3_k127_199943_0 Amidohydrolase family K06015 - 3.5.1.81 1.754e-250 786.0
HFD3_k127_199943_1 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 486.0
HFD3_k127_199943_2 Domain of unknown function (DUF3471) - - - 0.00000002452 60.0
HFD3_k127_2017064_0 cell shape determining protein MreB K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 541.0
HFD3_k127_2017064_1 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000004579 136.0
HFD3_k127_2017064_3 4Fe-4S binding domain K02574 - - 0.00000000000001174 85.0
HFD3_k127_2021578_0 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 4.365e-298 923.0
HFD3_k127_2021578_1 epimerase - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 1.434e-226 711.0
HFD3_k127_2021578_2 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 406.0
HFD3_k127_2021578_3 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006151 406.0
HFD3_k127_2021578_4 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004496 395.0
HFD3_k127_2021578_5 - - - - 0.000000000000000000000000000000000000000009676 158.0
HFD3_k127_2021578_6 iron dependent repressor - - - 0.00000000000000000000000000000000000000005357 158.0
HFD3_k127_2021578_7 s cog3422 K09946 GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000000000000000000000004431 130.0
HFD3_k127_2021578_8 Bacterial protein of unknown function (DUF853) K06915 - - 0.000000000000009225 78.0
HFD3_k127_2021578_9 Mo-molybdopterin cofactor metabolic process K03636,K21147 GO:0000096,GO:0000097,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.80,2.8.1.11 0.000000000005501 69.0
HFD3_k127_2034411_0 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003766 297.0
HFD3_k127_2034411_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000000000008763 235.0
HFD3_k127_2034411_2 Methylates ribosomal protein L11 K02687 - - 0.0000000000000000000000000000000000000000000000000189 190.0
HFD3_k127_2041302_0 Sensor histidine kinase PilS, PAS domain-containing K02668,K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000002025 247.0
HFD3_k127_2041302_1 response regulator K02667 - - 0.0000000000000000000000000000000000000000000000000000000000008359 217.0
HFD3_k127_2057449_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009037 551.0
HFD3_k127_2057449_1 Conserved hypothetical protein 95 - - - 0.00000000000000000004488 100.0
HFD3_k127_2073703_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009649 271.0
HFD3_k127_2073703_1 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000003088 168.0
HFD3_k127_2073703_2 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000007501 124.0
HFD3_k127_2090897_0 Molydopterin dinucleotide binding domain K00123,K05299 - 1.17.1.10,1.17.1.9 0.0 1097.0
HFD3_k127_2090897_1 Methylase involved in ubiquinone menaquinone K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 377.0
HFD3_k127_2090897_10 COG4968 Tfp pilus assembly protein PilE K02655 - - 0.000002427 55.0
HFD3_k127_2090897_2 ThiF family K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000737 368.0
HFD3_k127_2090897_3 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000001003 282.0
HFD3_k127_2090897_4 associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000006466 235.0
HFD3_k127_2090897_5 Transcription factor zinc-finger - - - 0.000000000000000000000000000000000000000000000000000000007713 206.0
HFD3_k127_2090897_6 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.000000000000000000000000000000000000000000000000000003701 194.0
HFD3_k127_2090897_7 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000003161 184.0
HFD3_k127_2090897_8 - - - - 0.0000000000000000000000000000000001006 143.0
HFD3_k127_2090897_9 Anti-sigma-K factor rskA - - - 0.000000000000000000000000000000000454 143.0
HFD3_k127_2098995_0 Amidase K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005271 563.0
HFD3_k127_2098995_1 Transposase K07491 - - 0.000000000000000000000000000000000000000000000000000001573 194.0
HFD3_k127_2098995_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000002451 147.0
HFD3_k127_2103928_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 4.785e-287 900.0
HFD3_k127_2103928_1 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752,K13818 - 2.7.7.77 0.000000000000000000002222 102.0
HFD3_k127_2117761_0 PFAM RNA-binding protein AU-1 Ribonuclease E G K08301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 478.0
HFD3_k127_2117761_1 DNA polymerase K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009206 446.0
HFD3_k127_2119393_0 ABC-type multidrug transport system ATPase component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 443.0
HFD3_k127_2119393_1 phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 373.0
HFD3_k127_2119393_10 Uncharacterized conserved protein (DUF2203) - - - 0.0000000000000000000006079 100.0
HFD3_k127_2119393_11 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.000003318 52.0
HFD3_k127_2119393_12 RDD family - - - 0.000009372 58.0
HFD3_k127_2119393_2 very-long-chain-acyl-CoA dehydrogenase activity K17880,K18817 - 2.7.1.119,2.7.1.163 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005715 306.0
HFD3_k127_2119393_3 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000006222 238.0
HFD3_k127_2119393_4 PFAM Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000002144 234.0
HFD3_k127_2119393_5 NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000002819 210.0
HFD3_k127_2119393_6 Fibronectin-binding protein - - - 0.00000000000000000000000000000000000000000000001465 189.0
HFD3_k127_2119393_7 MASE1 - - - 0.0000000000000000000000000000000000000000000001695 186.0
HFD3_k127_2119393_8 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.0000000000000000000000000407 124.0
HFD3_k127_2119393_9 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000522 112.0
HFD3_k127_2123100_0 Cupin 2, conserved barrel domain protein K16953,K19547 - 4.4.1.3,5.3.3.19 0.0000000000000000000000000001178 125.0
HFD3_k127_2123100_1 cAMP biosynthetic process - - - 0.00000000000000000000001324 115.0
HFD3_k127_2127820_0 Acyl-CoA dehydrogenase, N-terminal domain K16173 - 1.3.99.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 499.0
HFD3_k127_2127820_1 Xaa-Pro aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000002897 233.0
HFD3_k127_2127820_2 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000004965 168.0
HFD3_k127_2127820_3 triphosphatase activity - - - 0.00000000000002662 80.0
HFD3_k127_2127820_4 lytic transglycosylase activity K03194 - - 0.0000000000002561 82.0
HFD3_k127_2128517_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1095.0
HFD3_k127_21430_0 PFAM Integral membrane protein TerC K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 297.0
HFD3_k127_21430_1 GAF domain-containing protein K08968 - 1.8.4.14 0.0000000000000000000000000000000000000000000000000000000000000002464 224.0
HFD3_k127_21430_2 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.00000000000000000005648 90.0
HFD3_k127_21430_3 Peptidase family S41 K03797 - 3.4.21.102 0.0006895 47.0
HFD3_k127_2146311_0 Glycosyl hydrolase family 9 K01179 - 3.2.1.4 3.354e-248 794.0
HFD3_k127_2146311_1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 8.706e-202 636.0
HFD3_k127_2146311_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 557.0
HFD3_k127_2146311_3 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000003735 261.0
HFD3_k127_2146311_4 Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000000000221 175.0
HFD3_k127_2146311_5 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000004383 93.0
HFD3_k127_2146311_6 - - - - 0.00000000000001411 78.0
HFD3_k127_2146311_7 PFAM permease YjgP YjgQ family protein K07091 - - 0.00000000001607 78.0
HFD3_k127_2146311_8 PFAM permease YjgP YjgQ family protein K07091 - - 0.000000257 64.0
HFD3_k127_2151564_0 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007696 421.0
HFD3_k127_2151564_1 Pfam:Pyridox_oxidase K07006 - - 0.000000000000000000000000000000000000000000000000000000000000000001595 234.0
HFD3_k127_2151564_2 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000004062 207.0
HFD3_k127_2151564_3 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000001608 175.0
HFD3_k127_2151564_4 Putative stress-induced transcription regulator - - - 0.00000000000000000000000006148 114.0
HFD3_k127_2151564_5 PFAM Radical SAM - - - 0.00000000000000000000000007655 110.0
HFD3_k127_2151758_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 2.373e-280 888.0
HFD3_k127_2151758_1 PFAM peptidase T2 asparaginase 2 K13051 - 3.4.19.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003535 364.0
HFD3_k127_2151758_2 Transcriptional - - - 0.0000000000000000000000000000000000154 140.0
HFD3_k127_2151758_3 guanyl-nucleotide exchange factor activity - - - 0.00000000000000000000000000002584 130.0
HFD3_k127_2151758_4 COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases K01119,K11751 - 3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45 0.0002794 47.0
HFD3_k127_215743_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 7.881e-209 676.0
HFD3_k127_215743_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 450.0
HFD3_k127_215743_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009064 316.0
HFD3_k127_215743_3 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000000000000002306 229.0
HFD3_k127_215743_4 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000003524 165.0
HFD3_k127_215743_5 Putative metallopeptidase - - - 0.00000000000000000000000000000000000000000004555 172.0
HFD3_k127_215743_6 PFAM thioesterase superfamily K07107 - - 0.00000000000000000000000000000000002438 141.0
HFD3_k127_215743_7 - - - - 0.00004647 53.0
HFD3_k127_2172300_0 Tricorn protease homolog - - - 0.0 1021.0
HFD3_k127_2172300_1 - - - - 0.0000000000000000000000000000000000000000000000000002259 196.0
HFD3_k127_2172300_2 Tyrosine phosphatase family - - - 0.000000000000000000003689 100.0
HFD3_k127_2188604_0 Transcriptional regulator K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 434.0
HFD3_k127_2188604_1 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000001262 167.0
HFD3_k127_2188604_2 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000003157 161.0
HFD3_k127_2224209_0 Psort location CytoplasmicMembrane, score 10.00 - - - 0.000000000000000000000000000001975 135.0
HFD3_k127_2224209_2 Tetraacyldisaccharide-1-P 4'-kinase K00912 - 2.7.1.130 0.000001129 53.0
HFD3_k127_2234067_0 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 507.0
HFD3_k127_2234067_1 SIS domain K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000003756 221.0
HFD3_k127_2234067_2 transferase activity, transferring glycosyl groups - - - 0.000000000000004266 77.0
HFD3_k127_2239649_0 TIGRFAM parallel beta-helix repeat (two copies) K07218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 317.0
HFD3_k127_2239649_1 lipoprotein involved in nitrous oxide reduction - - - 0.00000000000000000000000000000000000000000000000000000000002071 213.0
HFD3_k127_2239649_2 ABC transporter K01990,K19340 - - 0.00000000000000000000000000000000000000000000000007869 186.0
HFD3_k127_2239649_3 NosL K19342 - - 0.00000000000000000009498 94.0
HFD3_k127_2239649_4 ABC-2 family transporter protein K01992,K19341 - - 0.000002986 50.0
HFD3_k127_2245300_0 - - - - 0.0000000000000000000000000000000000000000000000009819 185.0
HFD3_k127_2245300_1 TIGRFAM VWFA-related Acidobacterial domain - - - 0.0000000000000000007038 98.0
HFD3_k127_2246073_0 AcrB/AcrD/AcrF family K03296 - - 0.0 1032.0
HFD3_k127_2246073_1 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 507.0
HFD3_k127_2246073_2 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 411.0
HFD3_k127_2246073_3 AcrB/AcrD/AcrF family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007662 326.0
HFD3_k127_2246073_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001421 293.0
HFD3_k127_2246073_5 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000000000000001981 150.0
HFD3_k127_2246073_6 PFAM UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000002259 123.0
HFD3_k127_2246073_8 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.00000000001318 67.0
HFD3_k127_2249706_0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 350.0
HFD3_k127_2249706_1 Belongs to the glycosyl hydrolase 32 family K00692 - 2.4.1.10 0.000000000000000000000000000000000000000000000000000000000000000000008667 259.0
HFD3_k127_2249706_2 Copper binding periplasmic protein CusF K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000001062 241.0
HFD3_k127_2249706_3 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000001079 216.0
HFD3_k127_2249706_4 Amidohydrolase family K12960,K20810 - 3.5.4.28,3.5.4.31,3.5.4.40 0.000000000000000000000000000000000002402 145.0
HFD3_k127_2249706_5 Transcriptional regulator K07727 - - 0.000000000000000000000000000000327 123.0
HFD3_k127_2249706_6 MazG nucleotide pyrophosphohydrolase domain - - - 0.00000000000000000000000002772 112.0
HFD3_k127_2249706_8 COG2335, Secreted and surface protein containing fasciclin-like repeats - - - 0.00000001047 68.0
HFD3_k127_2251819_0 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 522.0
HFD3_k127_2251819_1 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000000003916 147.0
HFD3_k127_2255463_0 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 1.179e-225 708.0
HFD3_k127_2255463_1 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 568.0
HFD3_k127_2255463_10 Lysin motif K08307 - - 0.0001683 53.0
HFD3_k127_2255463_2 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008519 391.0
HFD3_k127_2255463_3 PFAM CBS domain K03699 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004589 387.0
HFD3_k127_2255463_4 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008586 337.0
HFD3_k127_2255463_5 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 325.0
HFD3_k127_2255463_6 Pirin K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 302.0
HFD3_k127_2255463_7 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002972 263.0
HFD3_k127_2255463_8 modulates the activities of several proteins which are inactive in their K12410 - - 0.000000000000000000000000000000000000000000000000000000000000009208 225.0
HFD3_k127_2255463_9 PFAM O-methyltransferase K00588 - 2.1.1.104 0.00000000000000000000000000000000000000000000000000008691 189.0
HFD3_k127_2312355_0 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000002575 255.0
HFD3_k127_2312355_1 Belongs to the glycosyl hydrolase 32 family K00692 - 2.4.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000353 263.0
HFD3_k127_2312355_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000003263 188.0
HFD3_k127_2312355_3 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.00000000000000000000000000000000001573 144.0
HFD3_k127_2312355_4 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000008201 88.0
HFD3_k127_2312355_5 Reprolysin (M12B) family zinc metalloprotease - - - 0.0000000004056 73.0
HFD3_k127_2321135_0 Belongs to the glycosyl hydrolase 32 family K00692 - 2.4.1.10 0.00000000000000000000000000000000000000000000000000000615 214.0
HFD3_k127_2321135_1 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000002032 159.0
HFD3_k127_2321135_2 Peptidoglycan-binding protein - - - 0.000000000000000000000000000000000000001245 169.0
HFD3_k127_2321135_3 Transposase and inactivated derivatives - - - 0.00000000000000000000009304 100.0
HFD3_k127_2349895_0 PAS domain K13924 - 2.1.1.80,3.1.1.61 2.959e-252 825.0
HFD3_k127_2349895_1 Response regulator receiver - - - 0.00000000000000000000000000000000001638 139.0
HFD3_k127_2360066_0 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000052 517.0
HFD3_k127_2360066_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000004674 258.0
HFD3_k127_2360066_2 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.0000000000000000000000000000000000000001589 162.0
HFD3_k127_2376004_0 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002782 311.0
HFD3_k127_2376004_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K00966,K16881 - 2.7.7.13,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000006586 258.0
HFD3_k127_2376004_2 Phosphomethylpyrimidine kinase K00868,K00941,K14153 - 2.5.1.3,2.7.1.35,2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000001286 243.0
HFD3_k127_2376004_3 eRF1 domain 3 - - - 0.00000000000000000000000000000000000000000000000000000000000002981 228.0
HFD3_k127_2376004_4 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000412 218.0
HFD3_k127_2376004_5 Tetratricopeptide repeats - - - 0.000000000000000000000000000000000000000005589 176.0
HFD3_k127_2376004_6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.000000000000000000000000000000000002721 145.0
HFD3_k127_2376004_7 helix_turn_helix, arabinose operon control protein - - - 0.000000001429 59.0
HFD3_k127_2376004_8 - - - - 0.00000003641 59.0
HFD3_k127_2377013_0 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001331 282.0
HFD3_k127_2377013_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001789 273.0
HFD3_k127_2377013_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000001467 212.0
HFD3_k127_2377013_3 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000005571 81.0
HFD3_k127_2379111_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 3.449e-222 705.0
HFD3_k127_2379111_1 Domain of unknown function (DUF305) - - - 0.000000000000000000000000000000000000000153 160.0
HFD3_k127_2379111_2 Nodulation protein S (NodS) - - - 0.000000000000000000000000006593 111.0
HFD3_k127_2379111_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02275,K17686 - 1.9.3.1,3.6.3.54 0.000000000000000000386 92.0
HFD3_k127_2379111_4 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 0.000000000000003202 77.0
HFD3_k127_2379111_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.00004449 52.0
HFD3_k127_2381719_0 Dipeptidyl peptidase IV (DPP IV) K01278 - 3.4.14.5 4.224e-201 640.0
HFD3_k127_2381719_1 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 399.0
HFD3_k127_2393786_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 429.0
HFD3_k127_2393786_1 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.000000000000000000000000000000000001302 146.0
HFD3_k127_2393786_2 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000000000007243 126.0
HFD3_k127_2393786_3 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000004903 123.0
HFD3_k127_2393786_4 protein with SCP PR1 domains - - - 0.00000000000000000000002782 105.0
HFD3_k127_2393786_5 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000008577 87.0
HFD3_k127_2397631_0 COGs COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001272 288.0
HFD3_k127_2397631_1 Inositol monophosphatase family K01082 - 3.1.3.7 0.00000000000000000000000000000000000000000000000000000000003656 216.0
HFD3_k127_2397631_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.0000000000000000005579 97.0
HFD3_k127_2403814_0 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005971 417.0
HFD3_k127_2403814_1 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000000000000000000000000000000000000000001724 198.0
HFD3_k127_2403814_2 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000000253 143.0
HFD3_k127_2403814_3 Protein of unknown function (DUF962) - - - 0.00000000000000000000000000000000002562 138.0
HFD3_k127_2403814_4 Putative esterase - - - 0.0000000000000000000000000000000001403 134.0
HFD3_k127_2403814_5 Putative cyclase K07130 - 3.5.1.9 0.0000000000000000000000000000000002999 137.0
HFD3_k127_2403814_6 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000001222 121.0
HFD3_k127_2403814_7 GCN5-related N-acetyl-transferase K06975 - - 0.000000000000000000000004276 104.0
HFD3_k127_2440520_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 541.0
HFD3_k127_2440520_1 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000009913 189.0
HFD3_k127_2440520_2 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000000000000000000438 144.0
HFD3_k127_2440520_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000003755 78.0
HFD3_k127_2440520_4 Redoxin family - - - 0.000006928 55.0
HFD3_k127_2440520_5 Belongs to the UPF0232 family - - - 0.0005378 48.0
HFD3_k127_2444285_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 3.865e-259 808.0
HFD3_k127_2444285_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005905 352.0
HFD3_k127_2444285_2 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007353 330.0
HFD3_k127_2444285_3 signal sequence binding K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005189 284.0
HFD3_k127_2444285_4 cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000008692 195.0
HFD3_k127_2447639_0 SIS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004336 441.0
HFD3_k127_2447639_1 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 348.0
HFD3_k127_2447639_2 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004195 339.0
HFD3_k127_2447639_3 Protein of unknown function (DUF1343) - - - 0.000000000000000000000000000000000000000000000001446 181.0
HFD3_k127_2447639_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000004874 148.0
HFD3_k127_2451610_0 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.00000000000000000000000000000000000009567 144.0
HFD3_k127_2451610_1 Tetratricopeptide repeat - - - 0.00007812 55.0
HFD3_k127_2451610_2 Anti-sigma regulatory factor (Ser Thr protein kinase) K04757,K06379,K08282 - 2.7.11.1 0.0001211 45.0
HFD3_k127_2451610_3 COG0671 Membrane-associated phospholipid phosphatase K19302 - 3.6.1.27 0.0005016 42.0
HFD3_k127_2452191_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004856 381.0
HFD3_k127_2452191_1 VIT family - - - 0.0000000000000000000000000000000000000000000001677 171.0
HFD3_k127_2452191_2 Glycosyl hydrolases family 15 K01178 - 3.2.1.3 0.0000000000000000000000000002086 115.0
HFD3_k127_2456540_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 363.0
HFD3_k127_2456540_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 362.0
HFD3_k127_2456540_2 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 349.0
HFD3_k127_2456540_3 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000282 215.0
HFD3_k127_2456540_4 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000001123 113.0
HFD3_k127_2456540_5 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000001227 104.0
HFD3_k127_2456540_6 Ribosomal L32p protein family K02911 - - 0.0000000000002151 71.0
HFD3_k127_2471206_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702,K08999 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009380,GO:0009628,GO:0032991,GO:0042802,GO:0044424,GO:0044464,GO:0050896,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 4.732e-269 842.0
HFD3_k127_2471206_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 3.059e-262 816.0
HFD3_k127_2471206_10 Bacterial regulatory protein, Fis family - - - 0.000003982 53.0
HFD3_k127_2471206_2 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 471.0
HFD3_k127_2471206_3 PFAM amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 404.0
HFD3_k127_2471206_4 SAICAR synthetase K01923,K13713 - 6.3.2.6,6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 346.0
HFD3_k127_2471206_5 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009936 277.0
HFD3_k127_2471206_6 beta barrel domain K07140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002346 267.0
HFD3_k127_2471206_7 FAD linked oxidase domain protein K00102,K00104 - 1.1.2.4,1.1.3.15 0.000000000000000000000000000000000000000000000000000462 191.0
HFD3_k127_2471206_8 Domain of unknown function (DUF1906) - - - 0.0000000000000000000000000000000000000000009988 166.0
HFD3_k127_2471206_9 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000003691 142.0
HFD3_k127_248576_0 Oligopeptidase - - - 5.41e-260 812.0
HFD3_k127_2491812_0 Uncharacterized protein family (UPF0051) K09014 - - 2.893e-236 737.0
HFD3_k127_2491812_1 Transcriptional regulator - - - 0.000000000000000000000000002441 117.0
HFD3_k127_2491812_2 ERAP1-like C-terminal domain K01256 - 3.4.11.2 0.00000089 51.0
HFD3_k127_2493293_0 ROK family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005478 432.0
HFD3_k127_2493293_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000091 282.0
HFD3_k127_2505649_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 448.0
HFD3_k127_2505649_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 392.0
HFD3_k127_2505649_2 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001297 289.0
HFD3_k127_2505649_3 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000002771 192.0
HFD3_k127_2505649_4 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000003548 104.0
HFD3_k127_2505649_5 Putative auto-transporter adhesin, head GIN domain - - - 0.00000000000000000000001041 108.0
HFD3_k127_2505649_6 R3H domain protein K06346 - - 0.000000000000000004927 89.0
HFD3_k127_2505649_7 PFAM Nuclease A inhibitor family protein - - - 0.000000000000005664 80.0
HFD3_k127_2505649_8 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000000001462 71.0
HFD3_k127_2505649_9 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000005938 73.0
HFD3_k127_2507773_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000001253 177.0
HFD3_k127_2507773_1 chaperone-mediated protein folding - - - 0.0000000000000000000000000000001515 140.0
HFD3_k127_2507773_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000006006 123.0
HFD3_k127_2509958_0 Catalyzes the conversion of 1-proline-5-carboxylate dehydrogenase to L-glutamate K00294 - 1.2.1.88 7.993e-206 653.0
HFD3_k127_2509958_1 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004681 559.0
HFD3_k127_2509958_10 Cysteine-rich secretory protein family - - - 0.00000000000000000001563 100.0
HFD3_k127_2509958_2 Acyclic terpene utilisation family protein AtuA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 494.0
HFD3_k127_2509958_3 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003992 311.0
HFD3_k127_2509958_4 PFAM Fatty acid hydroxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001278 259.0
HFD3_k127_2509958_5 Belongs to the UPF0176 family K07146 - - 0.00000000000000000000000000000000000000000000000000000000000000000007905 239.0
HFD3_k127_2509958_6 methylmalonyl-CoA mutase C-terminal K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000008797 203.0
HFD3_k127_2509958_7 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000001224 162.0
HFD3_k127_2509958_8 Haem-binding domain - - - 0.00000000000000000000000000000000000002137 149.0
HFD3_k127_2509958_9 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.0000000000000000000000000000000001706 140.0
HFD3_k127_2516907_0 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000022 293.0
HFD3_k127_2516907_1 Extracellular solute-binding protein K02048 - - 0.000000000000000000000000000000000000000000000000000000000000000003051 239.0
HFD3_k127_2516907_2 Sulfate ABC transporter inner membrane subunit CysT K02046 - - 0.0000000000000000000000000000000000000000000000004519 185.0
HFD3_k127_2516907_3 PAS domain K00575,K13924 - 2.1.1.80,3.1.1.61 0.00000000000000003474 83.0
HFD3_k127_2532788_0 Protein of unknown function (DUF1800) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009645 342.0
HFD3_k127_2532788_1 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003763 288.0
HFD3_k127_2532788_2 HhH-GPD superfamily base excision DNA repair protein - - - 0.000000000000000000000000000000000000000000000000000000000004796 218.0
HFD3_k127_2532788_3 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000001104 149.0
HFD3_k127_253539_0 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 295.0
HFD3_k127_253539_1 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000006488 154.0
HFD3_k127_253539_2 Belongs to the CDS family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.0000000000000000000000000000000001059 143.0
HFD3_k127_2546189_0 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000003767 214.0
HFD3_k127_2546189_1 peptidase activity - - - 0.0000000000000001063 88.0
HFD3_k127_2554674_0 ATPase associated with various cellular activities, AAA_3 K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001762 283.0
HFD3_k127_2554674_1 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000001099 243.0
HFD3_k127_2554674_2 cell adhesion involved in biofilm formation K13735,K20276 - - 0.00000000000000000000000000000000000000000000000000000000007998 223.0
HFD3_k127_2554674_3 pathogenesis - - - 0.00000000000005535 83.0
HFD3_k127_2554674_4 - - - - 0.0000000001823 73.0
HFD3_k127_2554674_5 Domain of unknown function (DUF4129) - - - 0.00003155 55.0
HFD3_k127_2566155_0 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000005227 154.0
HFD3_k127_2570134_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 362.0
HFD3_k127_2570134_1 Predicted methyltransferase regulatory domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 351.0
HFD3_k127_2570134_10 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.0000000000000004994 79.0
HFD3_k127_2570134_2 Putative neutral zinc metallopeptidase K07054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005457 301.0
HFD3_k127_2570134_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 298.0
HFD3_k127_2570134_4 Inward rectifier potassium channel K08715 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001063 290.0
HFD3_k127_2570134_5 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000002588 229.0
HFD3_k127_2570134_6 riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000003145 211.0
HFD3_k127_2570134_7 metallopeptidase activity - - - 0.000000000000000000000000000000000000000000000007566 184.0
HFD3_k127_2570134_8 bacterial (prokaryotic) histone like domain K03530 - - 0.00000000000000000000000000000004628 127.0
HFD3_k127_2570134_9 TM2 domain - - - 0.0000000000000000000000000000003922 127.0
HFD3_k127_2575121_0 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 297.0
HFD3_k127_2575121_1 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000005267 237.0
HFD3_k127_2575121_2 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000006158 186.0
HFD3_k127_2575121_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000007262 158.0
HFD3_k127_2575121_4 Belongs to the ompA family - - - 0.00000000000000000000000000000000003994 147.0
HFD3_k127_2575121_6 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC K16012,K16014 - - 0.0002882 52.0
HFD3_k127_2589516_0 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 408.0
HFD3_k127_2589516_1 Glycosyl transferase 4-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000001969 248.0
HFD3_k127_2589516_2 O-Antigen ligase K02847 - - 0.000000000000000000000000000000000000225 157.0
HFD3_k127_2589516_3 Adenylate cyclase - - - 0.0000006717 61.0
HFD3_k127_2602968_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 2.411e-220 696.0
HFD3_k127_2602968_1 pyrroloquinoline quinone binding - - - 0.00000000000000000000000000000000000000000007875 172.0
HFD3_k127_2609899_1 - - - - 0.000000000000000005753 92.0
HFD3_k127_2610785_0 PFAM ABC transporter K06020 - 3.6.3.25 6.711e-291 901.0
HFD3_k127_2610785_2 Subtilase family K17734 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 522.0
HFD3_k127_2610785_3 Belongs to the peptidase S8 family K17734 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 308.0
HFD3_k127_2610785_4 UvrD/REP helicase N-terminal domain K16898 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000001462 273.0
HFD3_k127_2610785_6 - - - - 0.0003012 52.0
HFD3_k127_2618495_0 CHASE3 domain - - - 1.746e-218 695.0
HFD3_k127_2618495_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 7.585e-206 657.0
HFD3_k127_2618495_10 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000001335 231.0
HFD3_k127_2618495_11 - - - - 0.0000000000000000000000000000000000000000000000000000004695 200.0
HFD3_k127_2618495_12 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.000000000000000000000000000000000000000000005305 177.0
HFD3_k127_2618495_13 Peptidase M56 - - - 0.000000000000000000000000000000001567 134.0
HFD3_k127_2618495_14 Universal stress protein family - - - 0.000000000000000000003901 99.0
HFD3_k127_2618495_15 mttA/Hcf106 family K03117 - - 0.0000000007375 65.0
HFD3_k127_2618495_2 Phosphoribosyl transferase domain K07100 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007706 580.0
HFD3_k127_2618495_3 Domains REC, sigma54 interaction, HTH8 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003491 433.0
HFD3_k127_2618495_4 Zinc-binding alcohol dehydrogenase family protein K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 412.0
HFD3_k127_2618495_5 Cellulose biosynthesis protein BcsQ K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006823 317.0
HFD3_k127_2618495_6 Type VI secretion system, VipA, VC_A0107 or Hcp2 K11900 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 328.0
HFD3_k127_2618495_7 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 310.0
HFD3_k127_2618495_8 Erythromycin esterase K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000007951 252.0
HFD3_k127_2618495_9 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009521 247.0
HFD3_k127_2621910_0 cellulose binding - - - 4.488e-316 990.0
HFD3_k127_2621910_1 Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate K00452 - 1.13.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000007336 257.0
HFD3_k127_2621910_2 Protein of unknown function (DUF1697) - - - 0.0000000000004649 74.0
HFD3_k127_2621910_3 - - - - 0.0000893 47.0
HFD3_k127_2626318_0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family K21310 - 2.1.1.334 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 317.0
HFD3_k127_2626318_1 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000004901 170.0
HFD3_k127_2626318_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000001538 147.0
HFD3_k127_2626318_3 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000009705 123.0
HFD3_k127_2655534_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 552.0
HFD3_k127_267035_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1e-273 852.0
HFD3_k127_267035_1 Transcriptional regulator K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001079 261.0
HFD3_k127_267035_2 YtxH-like protein - - - 0.0000002079 59.0
HFD3_k127_2670416_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 3.461e-199 643.0
HFD3_k127_2670416_1 - - - - 0.000000000000000000000000000000000000000000000000000008928 203.0
HFD3_k127_2670416_2 - - - - 0.00000009658 61.0
HFD3_k127_267087_0 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000001211 166.0
HFD3_k127_267087_1 Sigma-70 region 2 K03088 - - 0.000000000000000006889 91.0
HFD3_k127_2676726_0 (ABC) transporter K06147,K18890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008251 574.0
HFD3_k127_2676726_1 - - - - 0.0000000000000000000000000000000000000000000000009861 182.0
HFD3_k127_2676726_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000298 161.0
HFD3_k127_2676726_3 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000000000000000000000000000002982 128.0
HFD3_k127_2676726_4 RNA recognition motif - - - 0.0000000000000000000000000004044 115.0
HFD3_k127_2676726_5 Cupin 2, conserved barrel domain protein - - - 0.0000000000005351 78.0
HFD3_k127_2676726_6 Cro/C1-type HTH DNA-binding domain - - - 0.0000000002832 65.0
HFD3_k127_2676726_7 Cupin domain - - - 0.00002544 54.0
HFD3_k127_2676726_8 DNA-templated transcription, initiation K03088 - - 0.0006466 48.0
HFD3_k127_2699708_0 metallocarboxypeptidase activity K14054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005401 452.0
HFD3_k127_2699708_2 - - - - 0.00000000000000000000000000000000000000000000000000005331 194.0
HFD3_k127_2706418_0 choline dehydrogenase activity - - - 9.035e-215 675.0
HFD3_k127_2706418_1 Glycogen recognition site of AMP-activated protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007093 319.0
HFD3_k127_2706418_2 Major intrinsic protein K06188 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002823 248.0
HFD3_k127_2706418_3 Domain of unknown function (DUF4395) - - - 0.00000000000000000000000000000000000000000000000000000000000004722 218.0
HFD3_k127_2706418_4 RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000000000000000002661 186.0
HFD3_k127_2706418_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000003727 175.0
HFD3_k127_2706418_7 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.0000000000000000000001017 98.0
HFD3_k127_2706418_8 Putative zinc-finger - - - 0.00003119 51.0
HFD3_k127_2708776_0 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 471.0
HFD3_k127_2708776_1 cAMP biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009246 338.0
HFD3_k127_2708776_2 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 336.0
HFD3_k127_2708776_3 Belongs to the N(4) N(6)-methyltransferase family K00590 - 2.1.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000892 247.0
HFD3_k127_2708776_4 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.0000000000000000000000000000000000000000000000000000000000000000004916 238.0
HFD3_k127_2708776_5 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000007834 125.0
HFD3_k127_2737752_0 PFAM Protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000003944 181.0
HFD3_k127_2737752_1 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000106 138.0
HFD3_k127_2737752_2 - - - - 0.0000001996 56.0
HFD3_k127_2739342_0 NHL repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000002273 250.0
HFD3_k127_274259_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K15372 - 2.6.1.19,2.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003867 487.0
HFD3_k127_274259_1 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 331.0
HFD3_k127_2762104_0 Belongs to the ClpA ClpB family K03694 - - 2.654e-285 894.0
HFD3_k127_2762104_1 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005755 518.0
HFD3_k127_2762104_2 Fumarase C C-terminus K01744 - 4.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 413.0
HFD3_k127_2762104_3 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001025 255.0
HFD3_k127_2762104_4 - - - - 0.0000000000000000000000000000000007305 143.0
HFD3_k127_2762104_5 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000001286 106.0
HFD3_k127_2762104_6 von Willebrand factor type A domain - - - 0.0009346 50.0
HFD3_k127_2771211_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003175 562.0
HFD3_k127_2771211_2 - - - - 0.000000000000000003679 86.0
HFD3_k127_2771211_4 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.0000000006399 61.0
HFD3_k127_2771577_0 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004241 265.0
HFD3_k127_2771577_1 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.00000000000000000000000000000000000000000000000000000006677 199.0
HFD3_k127_2771577_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000143 143.0
HFD3_k127_2771577_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000002953 144.0
HFD3_k127_2771577_4 repeat protein - - - 0.0000000000000000000000003051 123.0
HFD3_k127_2771577_5 Domains in Na-Ca exchangers and integrin-beta4 - - - 0.00000009778 65.0
HFD3_k127_2782101_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 404.0
HFD3_k127_2782101_1 Peptidase M56, BlaR1 - - - 0.00000000000000000000000000000000000000000000000000452 199.0
HFD3_k127_2782101_2 PFAM Polysaccharide deacetylase - - - 0.0000000000000000000000000000000006061 138.0
HFD3_k127_2782101_3 PFAM Penicillinase repressor - - - 0.000000000000000000000000000000004478 132.0
HFD3_k127_2783111_0 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000212 301.0
HFD3_k127_2783111_1 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.0000000000000000000000000000005066 125.0
HFD3_k127_2783111_2 sequence-specific DNA binding - - - 0.0000000000000000001033 98.0
HFD3_k127_2783111_3 RibD C-terminal domain - - - 0.00001355 48.0
HFD3_k127_2791932_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 531.0
HFD3_k127_2791932_1 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 364.0
HFD3_k127_2791932_2 SPFH Band 7 PHB domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005358 289.0
HFD3_k127_2791932_3 inositol 2-dehydrogenase activity K00010,K03810 - 1.1.1.18,1.1.1.369 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002603 281.0
HFD3_k127_2791932_4 Xylose isomerase-like TIM barrel K06606 - 5.3.99.11 0.0000000000000000000000000000000000000000000000000000000000000004162 229.0
HFD3_k127_2791932_5 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000004166 121.0
HFD3_k127_2791932_6 transglycosylase K08309 - - 0.0000000000000000000000003519 121.0
HFD3_k127_2807459_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005874 329.0
HFD3_k127_2807459_1 phospholipase Carboxylesterase - - - 0.00000000000001153 79.0
HFD3_k127_2828855_0 PFAM peptidase M16 domain protein K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 327.0
HFD3_k127_2828855_1 Belongs to the UbiD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001826 261.0
HFD3_k127_2828855_2 Insulinase (Peptidase family M16) - - - 0.0002626 45.0
HFD3_k127_2838339_0 transport - - - 5.984e-314 1005.0
HFD3_k127_2838339_1 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000235 263.0
HFD3_k127_2838361_0 Belongs to the peptidase M16 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006236 320.0
HFD3_k127_2838361_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000003153 230.0
HFD3_k127_2838361_2 Zinc carboxypeptidase - - - 0.00000000000000000005697 91.0
HFD3_k127_2838361_3 - - - - 0.00000000000000108 86.0
HFD3_k127_2839934_0 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 469.0
HFD3_k127_2839934_1 GMP synthase (glutamine-hydrolyzing) activity K01951 - 6.3.5.2 0.0000000005193 70.0
HFD3_k127_2839934_2 Pfam:N_methyl_2 - - - 0.0004775 50.0
HFD3_k127_2849877_0 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003646 433.0
HFD3_k127_2849877_1 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000005285 174.0
HFD3_k127_2849877_2 - - - - 0.000000000000000000000000000000000000005819 149.0
HFD3_k127_2849877_3 - - - - 0.000000000000007633 81.0
HFD3_k127_2849877_4 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000008097 65.0
HFD3_k127_2850218_0 PFAM ribonuclease II K01147 - 3.1.13.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006073 488.0
HFD3_k127_2850218_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002953 298.0
HFD3_k127_2850218_2 Diacylglycerol kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001147 267.0
HFD3_k127_2863683_0 aminopeptidase K01256 - 3.4.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006936 291.0
HFD3_k127_2863683_1 Protein of unknown function (DUF420) K08976 - - 0.0000000000000000000000000000000000147 139.0
HFD3_k127_2863683_2 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.00000000000000000000000000000002951 129.0
HFD3_k127_2863683_3 cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.00000000000000000000000003698 117.0
HFD3_k127_2863683_4 CsbD-like - - - 0.0000003775 54.0
HFD3_k127_2867027_0 e3 binding domain K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 495.0
HFD3_k127_2867027_1 chlorophyll binding - - - 0.000001487 57.0
HFD3_k127_2882115_0 methyltransferase - - - 0.00000000000000000000000000000000000000000000006303 177.0
HFD3_k127_2888337_0 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002957 388.0
HFD3_k127_2888337_1 carboxylic acid catabolic process - - - 0.000000000000000000000000000000000000000002456 166.0
HFD3_k127_2888337_2 Transcriptional regulator, RpiR family - - - 0.0000000000007261 79.0
HFD3_k127_2888337_3 Polysaccharide deacetylase - - - 0.0004132 43.0
HFD3_k127_2890815_0 TonB dependent receptor K16090 - - 5.655e-214 689.0
HFD3_k127_2890815_1 Belongs to the proline racemase family K12658 GO:0003674,GO:0003824,GO:0016853,GO:0016854,GO:0016855,GO:0036361,GO:0047580,GO:0047661 5.1.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005857 407.0
HFD3_k127_2890815_2 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007414 290.0
HFD3_k127_2890815_3 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000002029 232.0
HFD3_k127_2890815_4 FAD dependent oxidoreductase K00303,K21061 - 1.5.3.1 0.000000000000000000000000000000000000000000000006232 179.0
HFD3_k127_2890815_5 Probable zinc-ribbon domain - - - 0.00000000007885 66.0
HFD3_k127_2901473_0 Amidohydrolase family - - - 4.255e-210 664.0
HFD3_k127_2901473_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 449.0
HFD3_k127_2901473_2 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000003384 224.0
HFD3_k127_2901473_3 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000004751 108.0
HFD3_k127_2934216_0 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004418 366.0
HFD3_k127_2934216_1 beta-glucosidase activity K05350 - 3.2.1.21 0.000000000000000000000000000000000000000000000005987 177.0
HFD3_k127_2934216_2 Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000001206 130.0
HFD3_k127_2960007_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008424 553.0
HFD3_k127_2960007_1 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004472 239.0
HFD3_k127_2960007_2 MgtE intracellular N domain - - - 0.0000000000000000000000000000000002198 147.0
HFD3_k127_2960007_3 metal ion transmembrane transporter activity - - - 0.00000000000000000000007357 106.0
HFD3_k127_2960007_4 Methyltransferase - - - 0.0001164 46.0
HFD3_k127_2978270_0 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 393.0
HFD3_k127_2978270_1 Belongs to the arylamine N-acetyltransferase family K00675 - 2.3.1.118 0.0000000000000000000000000000000000000000000000000000000000002697 222.0
HFD3_k127_3012756_0 Hydrolase - - - 0.0 1171.0
HFD3_k127_3012756_1 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000505 235.0
HFD3_k127_3012756_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000008463 152.0
HFD3_k127_3049_0 Vault protein inter-alpha-trypsin domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006248 612.0
HFD3_k127_3049_1 Saccharopine dehydrogenase C-terminal domain K19064 - 1.4.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005231 379.0
HFD3_k127_3049_2 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000024 287.0
HFD3_k127_3049_3 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000007817 219.0
HFD3_k127_3049_4 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000005935 221.0
HFD3_k127_3049_5 Phosphodiester glycosidase - - - 0.000000000000000000000000000000000000000006685 169.0
HFD3_k127_3049_6 COGs COG2905 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.00000000000000000000000000000000002534 139.0
HFD3_k127_3049_7 COG2335, Secreted and surface protein containing fasciclin-like repeats - - - 0.0000000000000000000003547 102.0
HFD3_k127_3049_8 3D domain protein - - - 0.00000000000000005546 87.0
HFD3_k127_3051160_0 GTP-binding protein TypA K06207 - - 3.521e-245 770.0
HFD3_k127_3051160_1 MatE - - - 2.512e-203 643.0
HFD3_k127_3051160_10 DoxX-like family - - - 0.0000000000000000000000000000000000001106 146.0
HFD3_k127_3051160_11 - - - - 0.0000000000000000000000000000000000002111 145.0
HFD3_k127_3051160_12 DinB family - - - 0.00000000000000000000000000000000002734 140.0
HFD3_k127_3051160_13 - - - - 0.00000000000000002899 87.0
HFD3_k127_3051160_2 Pyridine nucleotide-disulphide oxidoreductase K00529 - 1.18.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003232 546.0
HFD3_k127_3051160_3 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007679 269.0
HFD3_k127_3051160_4 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000000000000000000000000000008564 231.0
HFD3_k127_3051160_5 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000008683 232.0
HFD3_k127_3051160_6 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000000000001646 194.0
HFD3_k127_3051160_7 DNA-binding transcription factor activity - - - 0.000000000000000000000000000000000000000000000245 169.0
HFD3_k127_3051160_8 Transcriptional regulator - - - 0.0000000000000000000000000000000000000008634 155.0
HFD3_k127_3051160_9 HxlR-like helix-turn-helix - - - 0.00000000000000000000000000000000000000116 152.0
HFD3_k127_3068947_0 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K11102,K11103 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 354.0
HFD3_k127_3068947_1 PFAM Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000000007174 238.0
HFD3_k127_3068947_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000004676 228.0
HFD3_k127_3077888_0 Tricorn protease homolog K08676 - - 1.008e-222 701.0
HFD3_k127_3094358_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 4.361e-218 694.0
HFD3_k127_3094358_1 Thioredoxin - - - 0.0000000000000000000000000000000002555 141.0
HFD3_k127_3094358_2 - - - - 0.000000000001562 70.0
HFD3_k127_3094358_3 quinone binding - - - 0.0000008589 57.0
HFD3_k127_3094358_4 P pilus assembly Cpx signaling pathway, periplasmic inhibitor zinc-resistance associated protein K06006 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006457,GO:0008150,GO:0009987,GO:0010033,GO:0014070,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0044464,GO:0050896,GO:0051082,GO:0061077,GO:1990507 - 0.00004217 53.0
HFD3_k127_3096642_0 protein conserved in bacteria (DUF2179) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008659 324.0
HFD3_k127_3096642_1 cheY-homologous receiver domain K11443 - - 0.00000000000000000000001924 106.0
HFD3_k127_3096642_2 Universal stress protein family - - - 0.0000000008368 65.0
HFD3_k127_3105871_0 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 461.0
HFD3_k127_3105871_1 Glyoxalase-like domain K08234 - - 0.000000000000000000000000000000000000000000000000000214 190.0
HFD3_k127_3132044_0 DEAD DEAH box helicase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000195 260.0
HFD3_k127_3132044_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0000000000000000000000000000000000000000000003603 170.0
HFD3_k127_3135613_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 605.0
HFD3_k127_3135613_1 Ribosomal protein S1 K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006811 578.0
HFD3_k127_3135613_10 - - - - 0.0000000000000001311 87.0
HFD3_k127_3135613_2 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004015 481.0
HFD3_k127_3135613_3 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 460.0
HFD3_k127_3135613_4 pyrroloquinoline quinone binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005896 266.0
HFD3_k127_3135613_5 isomerase activity K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000000000000000000000000000004134 239.0
HFD3_k127_3135613_6 Beta-lactamase K17836 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000000006931 213.0
HFD3_k127_3135613_7 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.00000000000000000000000000000000000000000000001904 176.0
HFD3_k127_3135613_8 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.000000000000000000000000000008235 122.0
HFD3_k127_3135613_9 Protein of unknown function (DUF1059) - - - 0.000000000000000000009978 93.0
HFD3_k127_3152713_0 Phosphate acyltransferases K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009019 507.0
HFD3_k127_3152713_1 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008643 446.0
HFD3_k127_3152713_2 COG5285 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 380.0
HFD3_k127_3152713_3 PFAM peptidase M19 renal dipeptidase K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 331.0
HFD3_k127_3160746_0 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K07713,K07714,K19641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 408.0
HFD3_k127_3160746_1 Domain of unknown function (DUF3471) K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 394.0
HFD3_k127_3160746_10 Belongs to the sulfur carrier protein TusA family - - - 0.0000004229 57.0
HFD3_k127_3160746_11 SNARE associated Golgi protein - - - 0.0004353 44.0
HFD3_k127_3160746_2 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 385.0
HFD3_k127_3160746_3 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000002718 215.0
HFD3_k127_3160746_4 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000000000000000000000003207 136.0
HFD3_k127_3160746_5 - - - - 0.00000000000000000000000000000000003309 141.0
HFD3_k127_3160746_6 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.0000000000000000000000000000000002701 135.0
HFD3_k127_3160746_7 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000004757 141.0
HFD3_k127_3160746_8 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000000001522 79.0
HFD3_k127_3160746_9 peptidase S9 - - - 0.00000000005198 75.0
HFD3_k127_3189297_0 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 454.0
HFD3_k127_3189297_1 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000003689 250.0
HFD3_k127_3189297_2 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000002394 219.0
HFD3_k127_3189297_3 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000002174 130.0
HFD3_k127_3206772_0 hydrolase, family 3 K05349 - 3.2.1.21 1.105e-227 719.0
HFD3_k127_320793_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000003717 237.0
HFD3_k127_320793_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000000000000001094 130.0
HFD3_k127_320793_2 PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000000001678 104.0
HFD3_k127_320793_3 -acetyltransferase - - - 0.0000000000000000001967 92.0
HFD3_k127_3210329_0 Domain of unknown function (DUF5117) - - - 0.0 1055.0
HFD3_k127_3210329_1 DoxX K15977 - - 0.00000000000000000000000000000000000001146 149.0
HFD3_k127_3210329_2 YceI-like domain - - - 0.000000000000000000000000000115 118.0
HFD3_k127_3210329_3 Mycolic acid cyclopropane synthetase - - - 0.0000002889 54.0
HFD3_k127_3219159_0 TonB dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 360.0
HFD3_k127_3219159_1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K14257 - 1.14.19.49 0.000000000008495 73.0
HFD3_k127_3238165_0 Cytochrome C and Quinol oxidase polypeptide I - - - 3.003e-314 977.0
HFD3_k127_3238165_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 499.0
HFD3_k127_3238165_2 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006947 281.0
HFD3_k127_3238165_3 - - - - 0.000000000000000000000000000000003264 143.0
HFD3_k127_3238165_4 COG2346, Truncated hemoglobins K06886 - - 0.0000000000000000000000000000005247 128.0
HFD3_k127_3238165_5 - - - - 0.000000000000000000000005416 109.0
HFD3_k127_3238165_6 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.000000000000000000005085 96.0
HFD3_k127_3240366_0 COG0076 Glutamate decarboxylase and related PLP-dependent - - - 7.535e-216 679.0
HFD3_k127_3240366_1 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.000000000000000000000002838 104.0
HFD3_k127_3240366_2 Calcium/calmodulin dependent protein kinase II association domain - - - 0.0008285 47.0
HFD3_k127_3258319_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 3.277e-240 758.0
HFD3_k127_3258319_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 528.0
HFD3_k127_3258319_2 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 440.0
HFD3_k127_3258319_3 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.000000000000000000000000000000000000000000000000002156 188.0
HFD3_k127_3258319_4 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000002084 171.0
HFD3_k127_3258319_5 - - - - 0.000000000000000000000000002002 117.0
HFD3_k127_3258319_6 Transport and Golgi organisation 2 - - - 0.000000000002665 68.0
HFD3_k127_3267338_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 482.0
HFD3_k127_3267338_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946,K07123 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042357,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000004728 220.0
HFD3_k127_3267338_2 HNH endonuclease - - - 0.000000000000000000000000000000000004077 145.0
HFD3_k127_3267338_3 regulatory protein, MerR - - - 0.000000000000000000000000198 111.0
HFD3_k127_3267338_4 - - - - 0.000000000000000005374 89.0
HFD3_k127_3267338_5 Belongs to the 'phage' integrase family - - - 0.00007105 46.0
HFD3_k127_3268294_0 proline dipeptidase activity K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 376.0
HFD3_k127_3268294_1 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000007484 177.0
HFD3_k127_3268294_2 Serine hydrolase involved in the detoxification of formaldehyde K03930,K17076 - - 0.00000000000000000000000000000000000000000004878 174.0
HFD3_k127_3268294_3 - - - - 0.0000000000000000000000000000000000001752 145.0
HFD3_k127_3268294_4 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000007782 89.0
HFD3_k127_3268294_5 Transcription factor zinc-finger K09981 - - 0.000000008114 61.0
HFD3_k127_3281987_0 PFAM Peptidase family M20 M25 M40 K01436 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 588.0
HFD3_k127_3281987_1 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000004388 237.0
HFD3_k127_32883_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009795 337.0
HFD3_k127_32883_1 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000008565 177.0
HFD3_k127_32883_2 Helix-turn-helix XRE-family like proteins K07729 - - 0.0000000000006261 70.0
HFD3_k127_3331809_0 Pyridoxal-dependent decarboxylase conserved domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 543.0
HFD3_k127_3331809_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 481.0
HFD3_k127_3331809_2 membrane protein, TerC K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 388.0
HFD3_k127_3331809_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000001769 191.0
HFD3_k127_3331809_4 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000005577 140.0
HFD3_k127_3331809_5 - - - - 0.0000000000000000005882 88.0
HFD3_k127_3345001_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 1.411e-255 794.0
HFD3_k127_3345001_1 PFAM Proline dehydrogenase K00318 - - 0.000000000000000000000000000000005882 132.0
HFD3_k127_3345001_2 Domain of unknown function (DUF4252) - - - 0.000000000000000000000192 105.0
HFD3_k127_3345001_3 - - - - 0.000000000001207 75.0
HFD3_k127_3347032_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000671 275.0
HFD3_k127_3347032_1 cyclic nucleotide-binding K01420,K10914 - - 0.00000000000000000000000000000000000000000000000000000000000000002655 230.0
HFD3_k127_3347032_2 - - - - 0.0000000000000000000008009 103.0
HFD3_k127_3347032_3 cyclic nucleotide-binding K01420,K10914 - - 0.000000006287 63.0
HFD3_k127_3358010_0 Type VI secretion protein, EvpB/VC_A0108, tail sheath K11900 - - 3.222e-234 732.0
HFD3_k127_3358010_1 TIGRFAM type VI secretion protein, VC_A0110 family K11896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006407 614.0
HFD3_k127_3358010_10 metal cluster binding - - - 0.0000000000000000000000000000000000000000000000000000004148 207.0
HFD3_k127_3358010_11 Type VI secretion system effector, Hcp K11903 - - 0.0000000000000000000000000000000000000000005677 162.0
HFD3_k127_3358010_12 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000000000000006112 149.0
HFD3_k127_3358010_13 Gene 25-like lysozyme K11897 - - 0.00000000000000000000000000000001147 132.0
HFD3_k127_3358010_14 Type IV VI secretion system K11892 - - 0.00000000000000000000000000008339 124.0
HFD3_k127_3358010_15 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000000588 71.0
HFD3_k127_3358010_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004761 595.0
HFD3_k127_3358010_3 C-terminal, D2-small domain, of ClpB protein K11907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004382 507.0
HFD3_k127_3358010_4 type VI secretion protein, VC_A0114 family K11893 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009787 332.0
HFD3_k127_3358010_5 Pfam:T6SS_VasB K11895 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004689 304.0
HFD3_k127_3358010_6 ImcF-related N-terminal domain K11891 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003652 322.0
HFD3_k127_3358010_7 Protein conserved in bacteria K11902 - - 0.000000000000000000000000000000000000000000000000000000000000000001872 241.0
HFD3_k127_3358010_8 Protein of avirulence locus involved in temperature-dependent protein secretion K03217,K11898 - - 0.000000000000000000000000000000000000000000000000000000000000001706 227.0
HFD3_k127_3358010_9 Type VI secretion system, VipA, VC_A0107 or Hcp2 - - - 0.000000000000000000000000000000000000000000000000000000000002769 212.0
HFD3_k127_3362665_0 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000007545 196.0
HFD3_k127_3362665_1 tigr00255 - - - 0.00000000000000000000000000000000000000000003144 169.0
HFD3_k127_3362665_2 Protein of unknown function (DUF971) - - - 0.00000000000000000000003456 107.0
HFD3_k127_3362665_3 Protein of unknown function (DUF2847) - - - 0.0000000000000001634 86.0
HFD3_k127_3362665_4 Carbohydrate phosphorylase K00688,K00691 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.4.1.1,2.4.1.8 0.00000000000006565 72.0
HFD3_k127_3362665_5 integral membrane protein - - - 0.00003753 54.0
HFD3_k127_3362665_6 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0002197 47.0
HFD3_k127_337274_0 AMP-binding enzyme K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004946 519.0
HFD3_k127_337274_1 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003662 500.0
HFD3_k127_337274_2 UDP-glucose 4-epimerase activity K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003178 400.0
HFD3_k127_337274_3 Aminotransferase class I and II K10907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 347.0
HFD3_k127_337274_4 PFAM regulatory protein TetR K13770 - - 0.0000000000000000000000000000000000000000000001818 175.0
HFD3_k127_337274_5 Thioredoxin-like - - - 0.0000000000000000006868 93.0
HFD3_k127_337274_6 Polysaccharide biosynthesis/export protein K01991 - - 0.00000000002752 74.0
HFD3_k127_3378037_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008336 511.0
HFD3_k127_3378037_1 serine-type peptidase activity K01990,K08884,K12132,K18912 - 1.14.99.50,2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000352 349.0
HFD3_k127_3394820_0 peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008521 526.0
HFD3_k127_3394820_1 Aminotransferase class-III K00823 - 2.6.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 477.0
HFD3_k127_3394820_2 Protein of unknown function, DUF255 K00943 - 2.7.4.9 0.000000000000003698 77.0
HFD3_k127_3403278_0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006724 396.0
HFD3_k127_3403278_1 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 342.0
HFD3_k127_3403278_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000003181 265.0
HFD3_k127_3403278_3 - - - - 0.000000000004064 72.0
HFD3_k127_3404302_0 Belongs to the KdsA family K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000914 346.0
HFD3_k127_3404302_1 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000001298 164.0
HFD3_k127_3404302_2 Thioredoxin-like - - - 0.0000000000000000000000000000000000000002994 162.0
HFD3_k127_3422027_0 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 376.0
HFD3_k127_3422027_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 376.0
HFD3_k127_3422027_2 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000002432 249.0
HFD3_k127_3422027_3 beta-lactamase - - - 0.000000000000000000000001509 107.0
HFD3_k127_3422027_4 - - - - 0.0000000000000000000001663 103.0
HFD3_k127_342850_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005629 561.0
HFD3_k127_342850_1 protease with the C-terminal PDZ domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000544 507.0
HFD3_k127_342850_2 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002027 289.0
HFD3_k127_342850_3 Belongs to the glycosyl hydrolase 32 family K00692 - 2.4.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000008792 274.0
HFD3_k127_342850_4 DinB superfamily - - - 0.0000000000001693 80.0
HFD3_k127_3445110_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 552.0
HFD3_k127_3445110_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004794 262.0
HFD3_k127_3445110_2 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000001156 209.0
HFD3_k127_344718_0 PFAM Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004414 407.0
HFD3_k127_344718_1 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006098 361.0
HFD3_k127_344718_2 DEAD DEAH box helicase - - - 0.0000000000000000000000000000000000000000000000003637 185.0
HFD3_k127_34576_0 transporter - - - 6.569e-245 779.0
HFD3_k127_3460902_0 ATPase activity K09013 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 379.0
HFD3_k127_3460902_1 protein deglycation K05520 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000000000000000000001628 236.0
HFD3_k127_3460902_2 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000000000000000000000000000000000000000000001705 233.0
HFD3_k127_3460902_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000002046 162.0
HFD3_k127_3460902_4 oxidation-reduction process K09022 - 3.5.99.10 0.000000000000000000000000000000000003986 141.0
HFD3_k127_3460902_5 Cysteine desulfurase activator complex subunit SufB K09014 - - 0.000000000000003585 75.0
HFD3_k127_3460902_6 N-acetyltransferase K20838 - 2.3.1.80 0.00000000131 65.0
HFD3_k127_3460902_7 FeS assembly protein SufD K09015 - - 0.0000001456 57.0
HFD3_k127_3493615_0 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 339.0
HFD3_k127_3493615_1 COGs COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007029 345.0
HFD3_k127_3493615_10 GAF domain - - - 0.0000000000000000000000003237 114.0
HFD3_k127_3493615_11 PFAM Forkhead-associated protein - - - 0.000000000000000000001731 102.0
HFD3_k127_3493615_12 RDD family - - - 0.0000000000002715 77.0
HFD3_k127_3493615_13 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000004469 69.0
HFD3_k127_3493615_14 Yip1 domain - - - 0.0000000004902 69.0
HFD3_k127_3493615_15 histone H2A K63-linked ubiquitination - - - 0.00000003297 67.0
HFD3_k127_3493615_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 333.0
HFD3_k127_3493615_3 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004678 323.0
HFD3_k127_3493615_4 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 315.0
HFD3_k127_3493615_5 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007345 290.0
HFD3_k127_3493615_6 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001703 286.0
HFD3_k127_3493615_7 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000002644 230.0
HFD3_k127_3493615_8 - - - - 0.000000000000000000000000000000000000000000000000000001261 199.0
HFD3_k127_3493615_9 Efflux transporter, RND family, MFP subunit K02005 - - 0.00000000000000000000000000000000000000000000000004328 197.0
HFD3_k127_3498450_0 Peptidase M56 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 378.0
HFD3_k127_3498450_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002324 351.0
HFD3_k127_3498450_2 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005347 290.0
HFD3_k127_3498450_3 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000002144 191.0
HFD3_k127_3498450_4 Domain of unknown function (DUF4395) - - - 0.000000000000000000000000000000000000000006366 159.0
HFD3_k127_3498450_5 TIR domain - - - 0.0000000000000000000000000000002668 134.0
HFD3_k127_3551463_0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004982 288.0
HFD3_k127_3551463_1 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000000105 232.0
HFD3_k127_3551463_2 Belongs to the PEP-utilizing enzyme family K01006,K01007 - 2.7.9.1,2.7.9.2 0.000000000000000000000000000000000000000000000000000000000006411 216.0
HFD3_k127_3551463_3 transferase activity, transferring glycosyl groups K00720 - 2.4.1.80 0.0000000000000000000000000000000000000000000000000000003407 209.0
HFD3_k127_3551463_4 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000007522 133.0
HFD3_k127_3551463_5 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process - - - 0.0000000000000000000000008925 108.0
HFD3_k127_3585446_0 Cellulase (glycosyl hydrolase family 5) K19355 - 3.2.1.78 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008986 476.0
HFD3_k127_3585446_1 PFAM KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.0000000000000000000000000000000000000000000000000000000002395 210.0
HFD3_k127_3585446_2 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.0000000000000002073 88.0
HFD3_k127_3586890_0 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003675 429.0
HFD3_k127_3586890_1 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000002116 66.0
HFD3_k127_3612362_0 Glycosyl hydrolase family 57 K16149 - 2.4.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006181 572.0
HFD3_k127_3612362_1 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006048 455.0
HFD3_k127_3612362_2 Natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 361.0
HFD3_k127_3612362_3 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) - - - 0.000000000000000000000000000000000000000000000002286 177.0
HFD3_k127_3612362_4 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.000000000003016 76.0
HFD3_k127_3612362_5 IrrE N-terminal-like domain - - - 0.000005224 55.0
HFD3_k127_3612362_6 sequence-specific DNA binding - - - 0.000008215 55.0
HFD3_k127_3612362_7 PFAM PRC-barrel domain - - - 0.0002575 49.0
HFD3_k127_3618749_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005826 473.0
HFD3_k127_3618749_1 Protein of unknown function (DUF1385) - - - 0.000000000000000000000000000000000000000000000000000000000000000003892 241.0
HFD3_k127_3618749_2 Protein of unknown function DUF86 - - - 0.0000000000000000000000000000000006627 134.0
HFD3_k127_3618749_3 Phosphoglycerate mutase family - - - 0.000000000000000000000000000005598 128.0
HFD3_k127_3618749_4 Protein of unknown function (DUF421) - - - 0.000000000000134 72.0
HFD3_k127_3618749_5 PFAM Nucleotidyltransferase domain K07075 - - 0.000000000000711 72.0
HFD3_k127_3636740_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 372.0
HFD3_k127_3636740_1 Lysin motif - - - 0.00000000000000000000000000000002136 130.0
HFD3_k127_3636740_2 BON domain - - - 0.0000000000000001563 86.0
HFD3_k127_3636740_3 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.000000000000003831 83.0
HFD3_k127_3674503_0 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003485 618.0
HFD3_k127_3674503_1 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000176 295.0
HFD3_k127_3674503_2 PFAM ABC-2 type transporter K09690 - - 0.000000000000000000000000000000000000000000000000000000000000000000007427 244.0
HFD3_k127_3674503_3 ABC-type polysaccharide polyol phosphate transport system ATPase component K09691 - - 0.0000000000000000634 82.0
HFD3_k127_3685268_0 PFAM AMP-dependent synthetase and ligase K01897,K22319 - 6.1.3.1,6.2.1.3 2.484e-216 683.0
HFD3_k127_3685268_1 Aminotransferase class-V K01556 - 3.7.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 554.0
HFD3_k127_3685268_2 Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid K00486 - 1.14.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004747 475.0
HFD3_k127_3685268_3 Domain of unknown function (DUF1731) K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 304.0
HFD3_k127_3685268_4 arylformamidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001919 252.0
HFD3_k127_3685268_5 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000002222 184.0
HFD3_k127_3685268_6 PFAM peptidase M15B and M15C DD-carboxypeptidase VanY endolysin - - - 0.000000000000000000000000000000002236 141.0
HFD3_k127_3685268_7 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000001406 57.0
HFD3_k127_3685268_8 COG0076 Glutamate decarboxylase and related PLP-dependent - - - 0.0004742 44.0
HFD3_k127_3690107_0 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.0 1347.0
HFD3_k127_3690107_1 4Fe-4S single cluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 370.0
HFD3_k127_3690107_2 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 331.0
HFD3_k127_3690107_3 PspA/IM30 family K03969 - - 0.00000000000000000000000000000000000004819 153.0
HFD3_k127_3690107_4 - - - - 0.000000000000008656 84.0
HFD3_k127_3708334_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 2.951e-239 761.0
HFD3_k127_3708334_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000275 190.0
HFD3_k127_3711126_0 PFAM amino acid permease-associated region K03294 - - 1.938e-204 654.0
HFD3_k127_3711126_1 lyase activity K11645 GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0042802,GO:0044424,GO:0044444,GO:0044464 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007778 560.0
HFD3_k127_3711126_10 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000000000007698 168.0
HFD3_k127_3711126_11 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.000000000000003401 75.0
HFD3_k127_3711126_12 - - - - 0.0000000001797 69.0
HFD3_k127_3711126_13 - - - - 0.000000003597 65.0
HFD3_k127_3711126_2 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006855 418.0
HFD3_k127_3711126_3 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005152 384.0
HFD3_k127_3711126_4 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 356.0
HFD3_k127_3711126_5 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 289.0
HFD3_k127_3711126_6 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003804 267.0
HFD3_k127_3711126_7 Predicted membrane protein (DUF2231) - - - 0.0000000000000000000000000000000000000000000000000000000007689 205.0
HFD3_k127_3711126_8 membrane - - - 0.000000000000000000000000000000000000000000000000000000002472 205.0
HFD3_k127_3711126_9 COG0491 Zn-dependent hydrolases, including glyoxylases K01069 GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019243,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0061727,GO:0071704,GO:1901575,GO:1901615 3.1.2.6 0.00000000000000000000000000000000000000000000000008665 185.0
HFD3_k127_3730654_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 0.0 1213.0
HFD3_k127_3730654_1 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 453.0
HFD3_k127_3730654_2 MazG family K02499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004859 266.0
HFD3_k127_3730654_3 COGs COG1235 Metal-dependent hydrolase of the beta-lactamase superfamily I K06167 - 3.1.4.55 0.000000000000000000000000000000000000000000000000000000000000000000000313 246.0
HFD3_k127_3730654_6 Domain of unknown function (DUF1844) - - - 0.00000000000131 75.0
HFD3_k127_3730654_8 Belongs to the ompA family - - - 0.0000535 54.0
HFD3_k127_373106_0 IgGFc binding protein - - - 0.000000000000000000000000000000000000003276 165.0
HFD3_k127_3733711_0 GGDEF domain - - - 0.000000000000000000000000000000000000000000000000001535 195.0
HFD3_k127_3733711_1 lipopolysaccharide heptosyltransferase K02841,K02843 - - 0.00000000000000000000000000000000000000000000000002549 193.0
HFD3_k127_3733711_2 Phospholipid methyltransferase - - - 0.000000000000000000000000000000000000002032 153.0
HFD3_k127_3733711_3 Belongs to the Dps family K04047 - - 0.00000000000000005251 85.0
HFD3_k127_3733711_4 PFAM Fimbrial assembly family protein K02663 - - 0.0000003909 60.0
HFD3_k127_3733711_5 6-phosphogluconolactonase activity - - - 0.000006379 58.0
HFD3_k127_3733711_6 - - - - 0.0005702 50.0
HFD3_k127_3761899_0 FAD linked oxidase domain protein - - - 2.128e-215 677.0
HFD3_k127_3761899_1 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - - 0.00000000000000000000000000000000000000000000000000000000000001086 223.0
HFD3_k127_3761899_2 - - - - 0.000000000000000000005536 96.0
HFD3_k127_3773136_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 469.0
HFD3_k127_3773136_1 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.0000000000000000000000003741 108.0
HFD3_k127_3785427_0 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 343.0
HFD3_k127_3785427_1 PFAM GTP cyclohydrolase I Nitrile oxidoreductase K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000003454 239.0
HFD3_k127_3785427_2 PA domain - - - 0.00000000000000000000000000000000000000000000001699 177.0
HFD3_k127_3815550_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.0 1017.0
HFD3_k127_3815550_1 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001149 275.0
HFD3_k127_3815550_2 spore germination - - - 0.0000000000000000000000000000000000000000000000000000005431 204.0
HFD3_k127_3815550_3 Tyrosine phosphatase family - - - 0.000000000000000002885 92.0
HFD3_k127_3837589_0 CHAT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008606 359.0
HFD3_k127_3837589_1 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000003075 131.0
HFD3_k127_385629_0 4Fe-4S single cluster domain K06937 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 602.0
HFD3_k127_385629_1 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000001083 191.0
HFD3_k127_385629_2 lipoprotein localization to outer membrane K02004 - - 0.00000000000000000000000000000000000000000000001198 185.0
HFD3_k127_3870110_0 Tricorn protease homolog K08676 - - 0.0 1060.0
HFD3_k127_3870110_1 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000003638 229.0
HFD3_k127_3871226_0 transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 358.0
HFD3_k127_3871226_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004625 301.0
HFD3_k127_3871226_2 HD domain - - - 0.0000000000004982 77.0
HFD3_k127_3886239_0 PFAM Magnesium chelatase, ChlI subunit K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 616.0
HFD3_k127_3886239_1 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 419.0
HFD3_k127_3886239_2 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 284.0
HFD3_k127_3886239_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000001718 189.0
HFD3_k127_3886239_4 Domain of unknown function (DUF305) - - - 0.000000000000000000000000000000004768 133.0
HFD3_k127_3886239_5 manually curated - - - 0.000000000000000000000003896 104.0
HFD3_k127_3886239_6 Putative zinc-finger - - - 0.0002055 51.0
HFD3_k127_3891958_0 Aconitase family (aconitate hydratase) K01681 - 4.2.1.3 4.884e-314 977.0
HFD3_k127_3891958_1 bacterial-type flagellum-dependent cell motility - - - 0.000000000000000000000003172 119.0
HFD3_k127_3893670_0 peptidase S41 - - - 6.918e-216 694.0
HFD3_k127_3893670_1 Thiolase, C-terminal domain K00632 - 2.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 548.0
HFD3_k127_3893670_2 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.00000000000000000001123 94.0
HFD3_k127_3914049_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 5.26e-256 807.0
HFD3_k127_3914049_1 Carbamoyl-phosphate synthetase large chain domain protein K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 592.0
HFD3_k127_3914049_2 Belongs to the class-II aminoacyl-tRNA synthetase family K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007525 523.0
HFD3_k127_3914049_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 430.0
HFD3_k127_3914049_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008677 253.0
HFD3_k127_3914049_5 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000000183 181.0
HFD3_k127_3914049_6 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000435 175.0
HFD3_k127_3914049_7 Biotin-requiring enzyme K02160 - - 0.000000000000000000000000000000000000007754 151.0
HFD3_k127_3914049_8 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.000000000000000000000000000003389 123.0
HFD3_k127_3914049_9 Ribosomal protein L17 K02879 - - 0.0000000000000000000000000001389 121.0
HFD3_k127_3917115_0 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000002997 244.0
HFD3_k127_3923408_0 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007629 297.0
HFD3_k127_3923408_1 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000006633 235.0
HFD3_k127_3923408_2 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000006019 229.0
HFD3_k127_3923408_3 N-terminal TM domain of oligopeptide transport permease C - - - 0.00000000000000000000000001513 111.0
HFD3_k127_3923408_4 Insulinase (Peptidase family M16) - - - 0.00000000001161 77.0
HFD3_k127_3923408_5 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0004307 52.0
HFD3_k127_3936352_0 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000002142 267.0
HFD3_k127_3936352_1 Nodulation protein S (NodS) - - - 0.0000000000000000000000000000000000000000000000000000000000000000007444 233.0
HFD3_k127_3936352_2 enzyme binding K00567,K07443 - 2.1.1.63 0.0000000000000000000000003532 109.0
HFD3_k127_3936352_3 Peptidylprolyl isomerase K03770 - 5.2.1.8 0.00000000000000002305 91.0
HFD3_k127_3936352_4 Putative cyclase K07130 - 3.5.1.9 0.000000002715 58.0
HFD3_k127_3942318_0 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000001032 197.0
HFD3_k127_3942318_1 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.0000000000000000000000000001074 119.0
HFD3_k127_3942318_2 sister chromatid segregation - - - 0.0000000114 67.0
HFD3_k127_3942318_3 Belongs to the PstS family K02040 - - 0.000002697 53.0
HFD3_k127_3945000_0 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 584.0
HFD3_k127_3945000_1 Peptidase dimerisation domain K01295 - 3.4.17.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005836 414.0
HFD3_k127_3945000_2 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009355 414.0
HFD3_k127_3945000_3 Belongs to the glycosyl hydrolase 32 family K00692 - 2.4.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000001151 282.0
HFD3_k127_3945000_4 Domain of unknown function (DUF3488) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001112 271.0
HFD3_k127_3945000_5 Zinc metalloprotease (Elastase) - - - 0.00000000000000000000000000000000000000000000000000262 210.0
HFD3_k127_3945000_6 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000000000000002896 95.0
HFD3_k127_3945000_7 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.000000000001426 82.0
HFD3_k127_3945000_8 PKD domain - - - 0.0000484 57.0
HFD3_k127_397521_0 Ftsk_gamma K03466 - - 0.0000000000000000000000000000000000000000000223 166.0
HFD3_k127_397521_1 TIGRFAM competence protein ComEA helix-hairpin-helix K02237 - - 0.0000000000002614 74.0
HFD3_k127_397521_2 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.00000001492 65.0
HFD3_k127_3994157_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1133.0
HFD3_k127_3994157_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 386.0
HFD3_k127_3994157_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 311.0
HFD3_k127_3994157_3 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000002534 247.0
HFD3_k127_3994157_4 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000003424 208.0
HFD3_k127_3994157_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000003786 177.0
HFD3_k127_3994157_6 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000001715 169.0
HFD3_k127_3994157_7 - - - - 0.000000000000000001521 89.0
HFD3_k127_3998815_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 5.586e-222 699.0
HFD3_k127_3998815_1 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008602 485.0
HFD3_k127_3998815_2 cytochrome c nitrite reductase K15876 - - 0.000000000000000000000000000000000000000000000000000000006734 201.0
HFD3_k127_3998815_3 Methyltransferase domain - - - 0.00000000000000000000000000000000006531 142.0
HFD3_k127_3998815_4 hydrolase family 92 - - - 0.000000000007397 65.0
HFD3_k127_4002012_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 493.0
HFD3_k127_4002012_1 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.00000000000000000000000000000000000000002076 155.0
HFD3_k127_4002012_2 PFAM Tetratricopeptide repeat - - - 0.000004551 58.0
HFD3_k127_4011461_0 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000001567 216.0
HFD3_k127_4011461_1 Histidine kinase K07646 - 2.7.13.3 0.0000000001942 63.0
HFD3_k127_4011461_2 heat shock protein binding - - - 0.0000003013 63.0
HFD3_k127_4016668_0 AcrB/AcrD/AcrF family K03296 - - 1.777e-291 916.0
HFD3_k127_4016668_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000000000000000000000000000004255 151.0
HFD3_k127_4018527_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 4.844e-247 777.0
HFD3_k127_4018527_1 bacterial-type flagellum-dependent cell motility - - - 0.000000000000000433 87.0
HFD3_k127_4024240_0 ABC transporter, transmembrane K18889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 538.0
HFD3_k127_4024240_1 GDSL-like Lipase/Acylhydrolase - - - 0.00000000000000000000000000000000000000000003614 172.0
HFD3_k127_4024240_2 - - - - 0.000000000000000001448 93.0
HFD3_k127_4024240_3 Thioesterase superfamily - - - 0.00000000000000009103 85.0
HFD3_k127_4032465_0 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 309.0
HFD3_k127_4032465_1 histidyl-tRNA synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004885 265.0
HFD3_k127_4032465_2 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000000000000001914 173.0
HFD3_k127_4032465_3 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000005927 168.0
HFD3_k127_4032465_4 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000001611 157.0
HFD3_k127_4032465_5 Penicillin binding protein transpeptidase domain K05364 - - 0.0001065 51.0
HFD3_k127_4036016_0 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003119 495.0
HFD3_k127_4036016_1 C-terminal domain of 1-Cys peroxiredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003916 359.0
HFD3_k127_4036016_2 LmbE family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002549 271.0
HFD3_k127_4036016_3 SMART CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000009972 201.0
HFD3_k127_4036016_4 Biotin-requiring enzyme - - - 0.00000000000000000000002836 107.0
HFD3_k127_4036016_5 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.00000000007797 67.0
HFD3_k127_4036016_6 - - - - 0.000000003186 63.0
HFD3_k127_40568_0 PFAM D-aminoacylase, C-terminal region K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 575.0
HFD3_k127_40568_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000001196 81.0
HFD3_k127_40568_2 PFAM Protein kinase domain - - - 0.00004163 55.0
HFD3_k127_4056835_0 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000839 304.0
HFD3_k127_4056835_1 Allophanate hydrolase subunit 1 - - - 0.0000000000000000000000000000000000000000000000000000000009783 208.0
HFD3_k127_4056835_2 allophanate hydrolase subunit 2 K06350 - - 0.000000000002031 69.0
HFD3_k127_4061966_0 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001284 279.0
HFD3_k127_4061966_1 Amidohydrolase family - - - 0.00000000000000000000269 98.0
HFD3_k127_406652_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 586.0
HFD3_k127_406652_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006994 379.0
HFD3_k127_406652_2 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000000000000000002966 154.0
HFD3_k127_4094560_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 452.0
HFD3_k127_4094560_1 Cysteine-rich secretory protein family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 332.0
HFD3_k127_4094560_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.0000000000000000000000000000000000000001254 169.0
HFD3_k127_4094560_3 outer membrane efflux protein K15725 - - 0.000000001933 68.0
HFD3_k127_4094560_4 Belongs to the glycosyl hydrolase 32 family K01193 - 3.2.1.26 0.000000002845 59.0
HFD3_k127_4103341_0 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 321.0
HFD3_k127_4103341_1 O-Antigen ligase K02847 - - 0.0000000000000000000000000000000001433 149.0
HFD3_k127_4103341_2 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000001643 85.0
HFD3_k127_4103341_4 SMART RNA-processing protein HAT helix repeating-containing protein - - - 0.0001905 53.0
HFD3_k127_4111422_0 Part of the ABC transporter complex XylFGH involved in xylose import. Responsible for energy coupling to the transport system K10441,K10545 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007676 590.0
HFD3_k127_4111422_1 Putative glucoamylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006102 410.0
HFD3_k127_4111422_2 4Fe-4S double cluster binding domain K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004569 345.0
HFD3_k127_4111422_3 Branched-chain amino acid transport system / permease component K10544 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 340.0
HFD3_k127_4111422_4 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005767 312.0
HFD3_k127_4111422_5 hydrolase, family 3 K05349 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004653 319.0
HFD3_k127_4111422_6 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001283 291.0
HFD3_k127_4115147_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 565.0
HFD3_k127_4115147_1 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 436.0
HFD3_k127_4115147_2 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003185 372.0
HFD3_k127_4115147_3 Peptidase M16 inactive domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001083 263.0
HFD3_k127_4115147_4 Tryptophan synthase alpha chain K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000009255 245.0
HFD3_k127_4115147_5 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000005433 234.0
HFD3_k127_4115147_6 Belongs to the TrpC family K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000413 212.0
HFD3_k127_4115147_7 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000005453 183.0
HFD3_k127_4115147_8 sequence-specific DNA binding - - - 0.000000000005559 71.0
HFD3_k127_4115147_9 Rad52 22 double-strand break repair protein - GO:0001101,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009269,GO:0009314,GO:0009414,GO:0009415,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0010035,GO:0010212,GO:0010332,GO:0031668,GO:0033554,GO:0034641,GO:0042221,GO:0042631,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0070887,GO:0071214,GO:0071229,GO:0071462,GO:0071465,GO:0071478,GO:0071479,GO:0071480,GO:0071496,GO:0071704,GO:0090304,GO:0104004,GO:1901360,GO:1901700,GO:1901701 - 0.00001017 57.0
HFD3_k127_4127807_0 PFAM Zinc carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003795 607.0
HFD3_k127_4127807_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 516.0
HFD3_k127_4127807_2 Homocysteine S-methyltransferase K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000009008 251.0
HFD3_k127_4127807_3 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000001852 228.0
HFD3_k127_4127807_4 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000000000000000000000000003157 209.0
HFD3_k127_4127807_5 Phosphate acyltransferases K00655,K15781 - 2.3.1.51,3.1.3.3 0.000000000000000000000000000000000002194 149.0
HFD3_k127_4127807_6 - - - - 0.00000000000000000000000000000000001501 141.0
HFD3_k127_4127807_7 Belongs to the TPP enzyme family K01637 - 4.1.3.1 0.000000000000000000000000001213 126.0
HFD3_k127_4127807_8 Protein of unknown function (DUF2905) - - - 0.000000000000000000001064 96.0
HFD3_k127_4140822_0 Male sterility protein K01897 - 6.2.1.3 0.0 1169.0
HFD3_k127_4140822_1 Glycosyl hydrolase family 47 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001269 281.0
HFD3_k127_4142761_0 Heat shock 70 kDa protein K04043 - - 1.111e-284 887.0
HFD3_k127_4142761_1 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004903 526.0
HFD3_k127_4142761_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 383.0
HFD3_k127_4142761_3 Metallophosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000005076 198.0
HFD3_k127_4142761_4 MerR HTH family regulatory protein K13640 - - 0.00000000000000000000000000000000000002057 147.0
HFD3_k127_4142761_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.0000000000000000000000000000001528 130.0
HFD3_k127_4142761_6 TonB dependent receptor - - - 0.00000000000000000000000000009637 125.0
HFD3_k127_4142761_7 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.00000000000003794 74.0
HFD3_k127_414916_0 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000571 467.0
HFD3_k127_414916_1 pfam abc1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003012 370.0
HFD3_k127_414916_2 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000007706 260.0
HFD3_k127_414916_3 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009503 257.0
HFD3_k127_414916_4 PFAM Nickel cobalt transporter, high-affinity - - - 0.000000000000000000000000000000000000000000001285 173.0
HFD3_k127_414916_5 Carbohydrate family 9 binding domain-like - - - 0.0000000000000000000000000004673 124.0
HFD3_k127_414916_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00002731 51.0
HFD3_k127_414916_8 methyltransferase - - - 0.000293 51.0
HFD3_k127_4161731_0 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005726 499.0
HFD3_k127_4161731_1 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related K01295 - 3.4.17.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 297.0
HFD3_k127_4161731_2 S1/P1 Nuclease - - - 0.00000000000000000000000000000000000000000000000000000000000001972 227.0
HFD3_k127_4161731_3 DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000007721 201.0
HFD3_k127_4167183_0 SMART Elongator protein 3 MiaB NifB - - - 5.297e-228 716.0
HFD3_k127_4167183_1 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000382 335.0
HFD3_k127_4167183_2 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 323.0
HFD3_k127_4167183_3 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000074 319.0
HFD3_k127_4167183_4 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634 317.0
HFD3_k127_4167183_5 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003874 314.0
HFD3_k127_4167183_6 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000008188 141.0
HFD3_k127_4251609_0 PFAM TonB-dependent Receptor Plug K02014,K16089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004087 471.0
HFD3_k127_4266970_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 481.0
HFD3_k127_4280086_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960,K20810 GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270 3.5.4.28,3.5.4.31,3.5.4.40 0.0000000000000000000000000000000002818 141.0
HFD3_k127_4280086_1 Transglycosylase SLT domain K08309 - - 0.00000000000000000000008506 106.0
HFD3_k127_4280086_2 PIN domain - - - 0.000000000000000000000532 101.0
HFD3_k127_4288922_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 517.0
HFD3_k127_4306506_0 Periplasmic component of the Tol biopolymer transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 364.0
HFD3_k127_4306506_1 Transcriptional regulator, Crp Fnr family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006209 285.0
HFD3_k127_4306506_2 COGs COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000007763 216.0
HFD3_k127_4306506_3 Transcriptional regulatory protein, C terminal K18349 - - 0.000000000002625 74.0
HFD3_k127_4322346_0 Zinc metalloprotease (Elastase) K20274 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 389.0
HFD3_k127_4322346_1 dextransucrase activity - - - 0.00000000000000000000000000000000000000000000000000000000000002952 246.0
HFD3_k127_4322346_2 Zinc metalloprotease (Elastase) K20274 - - 0.000000000000000000000000000000000000000000000002389 193.0
HFD3_k127_4337102_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 8.849e-311 979.0
HFD3_k127_4337102_1 Glycosyl hydrolase family 20, catalytic domain K12373 - 3.2.1.52 2.651e-195 635.0
HFD3_k127_4337102_10 Putative lumazine-binding - - - 0.0000000000000000000000000000001188 128.0
HFD3_k127_4337102_11 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000000000000000000005094 122.0
HFD3_k127_4337102_2 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000728 368.0
HFD3_k127_4337102_3 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 367.0
HFD3_k127_4337102_4 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000001199 265.0
HFD3_k127_4337102_5 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000002749 212.0
HFD3_k127_4337102_6 Transposase IS200 like K07491 - - 0.000000000000000000000000000000000000000000000000000000001666 203.0
HFD3_k127_4337102_7 Transposase IS200 like - - - 0.00000000000000000000000000000000000000000000000002265 186.0
HFD3_k127_4337102_8 Chitobiase/beta-hexosaminidase C-terminal domain - - - 0.0000000000000000000000000000000000000000001059 162.0
HFD3_k127_4337102_9 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000003229 132.0
HFD3_k127_4393886_0 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 419.0
HFD3_k127_4393886_1 TonB-dependent receptor - - - 0.000000000000000000000001341 121.0
HFD3_k127_4393886_2 Domain of unknown function (DUF4388) K04562 - - 0.00006289 53.0
HFD3_k127_4415666_0 Glycosyl hydrolase-like 10 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 372.0
HFD3_k127_4415666_1 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005711 353.0
HFD3_k127_4415666_2 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11 0.000000000000000000000000000000000000000000000000000000000000000001148 235.0
HFD3_k127_4415666_3 COG1278 Cold shock proteins K03704 - - 0.000000000000000000000003741 105.0
HFD3_k127_4415666_4 - - - - 0.0000000000000003914 83.0
HFD3_k127_4423074_0 Cupin domain - - - 0.00000000000000000000000000000000000000000000000006279 181.0
HFD3_k127_4423074_1 OsmC-like protein K07397 - - 0.00000000000000000000000000000000002711 143.0
HFD3_k127_4423074_2 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000003778 124.0
HFD3_k127_4423074_3 DinB family - - - 0.0000000000000000006464 92.0
HFD3_k127_4423074_4 - K01611 - 4.1.1.50 0.00000000001296 69.0
HFD3_k127_4426453_0 Multicopper oxidase K08100 - 1.3.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 503.0
HFD3_k127_4434196_0 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 364.0
HFD3_k127_4434196_1 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004063 344.0
HFD3_k127_4434196_2 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003146 258.0
HFD3_k127_4434196_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458,K14660 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000002469 202.0
HFD3_k127_4434196_4 Protein of unknown function (DUF1810) - - - 0.0000000000000000000000000000000000000000000002905 172.0
HFD3_k127_4434196_5 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0008326 44.0
HFD3_k127_4436940_0 Cupin 2, conserved barrel domain protein K11477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 329.0
HFD3_k127_4436940_1 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 341.0
HFD3_k127_4436940_2 Transport and Golgi organisation 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000005113 226.0
HFD3_k127_4436940_3 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000000000000000000003727 178.0
HFD3_k127_4436940_4 - - - - 0.0000000000000000000000000000000255 132.0
HFD3_k127_4436940_5 DinB family - - - 0.000000000000000000487 96.0
HFD3_k127_447166_0 COG1914 Mn2 and Fe2 transporters of the NRAMP family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000355 470.0
HFD3_k127_447166_1 Belongs to the UPF0271 (lamB) family K07160 - - 0.0000000000000000000000000000000000000000000000000000000006403 206.0
HFD3_k127_447166_2 von Willebrand factor, type A - - - 0.000000000000000000000000000000005132 142.0
HFD3_k127_4481816_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 473.0
HFD3_k127_4481816_1 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000000000002705 138.0
HFD3_k127_4481816_2 Acetyltransferase (GNAT) domain K03817 - - 0.000000004619 57.0
HFD3_k127_4520614_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008329 345.0
HFD3_k127_4520614_1 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007372 289.0
HFD3_k127_4520614_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000007999 121.0
HFD3_k127_4527590_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 494.0
HFD3_k127_4527590_1 PLD-like domain K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006421 456.0
HFD3_k127_4527590_2 thiamine diphosphate biosynthetic process K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004678 326.0
HFD3_k127_4527590_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000006257 240.0
HFD3_k127_4527590_4 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000616 241.0
HFD3_k127_4527590_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000005375 150.0
HFD3_k127_4527590_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000001089 130.0
HFD3_k127_4527590_7 ThiS family - - - 0.00000000000004698 74.0
HFD3_k127_4527590_8 - - - - 0.000000000136 72.0
HFD3_k127_4527590_9 Molybdopterin converting factor, small subunit K03636 - - 0.0001288 50.0
HFD3_k127_4530820_0 RmlD substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 443.0
HFD3_k127_4530820_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003216 280.0
HFD3_k127_4530820_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000001381 247.0
HFD3_k127_4530820_3 RDD family - - - 0.000000000000000000000000000000000000000005158 165.0
HFD3_k127_4530820_4 YCII-related domain - - - 0.000000000000000000000000000000000001239 143.0
HFD3_k127_4530820_5 Protein of unknown function (DUF3788) - - - 0.00000000000000000000000000001203 123.0
HFD3_k127_4530820_6 Thioredoxin-like domain - - - 0.00000000000000000000000000002877 122.0
HFD3_k127_4530820_7 Domain of unknown function (DUF4287) - - - 0.0000000000000000000000000001639 117.0
HFD3_k127_4536619_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 396.0
HFD3_k127_4536619_1 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 343.0
HFD3_k127_4536619_2 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 329.0
HFD3_k127_4536619_3 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 322.0
HFD3_k127_4536619_4 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 316.0
HFD3_k127_4536619_5 Transcriptional regulator K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005091 273.0
HFD3_k127_4536619_6 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006453 262.0
HFD3_k127_454988_0 Asparaginase K13051 - 3.4.19.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005257 388.0
HFD3_k127_454988_1 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000006059 220.0
HFD3_k127_454988_2 Belongs to the CinA family K03742 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000002177 216.0
HFD3_k127_454988_3 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000001807 147.0
HFD3_k127_455_0 Sodium/calcium exchanger protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 497.0
HFD3_k127_455_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004828 435.0
HFD3_k127_455_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004463 299.0
HFD3_k127_455_3 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000005085 231.0
HFD3_k127_455_4 Putative restriction endonuclease - - - 0.0000000000000000000000000000307 124.0
HFD3_k127_4557271_0 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 3.204e-243 762.0
HFD3_k127_4557271_1 Domain of unknown function (DUF1972) K12996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 389.0
HFD3_k127_4557271_2 UPF0314 protein - - - 0.000000000000000000000000000000000000000000000000002969 189.0
HFD3_k127_4557271_3 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.000000000000000000000000000000000000000000000000005503 184.0
HFD3_k127_4557271_4 group 2 family protein - - - 0.0000000000000000000000000000000000000000000000141 181.0
HFD3_k127_4557271_5 glycosyl transferase family 2 K07011,K20444 - - 0.00000000000000000000000000000000000000000000003887 175.0
HFD3_k127_4557271_6 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) K10794 - 1.21.4.1 0.00000000000000000000000001192 119.0
HFD3_k127_4557271_7 Domain of unknown function (DUF4149) - - - 0.00000000003312 70.0
HFD3_k127_4557271_8 X-Pro dipeptidyl-peptidase (S15 family) K06889 - - 0.0000003128 61.0
HFD3_k127_4617402_0 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit K01768,K07315 - 3.1.3.3,4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006841 320.0
HFD3_k127_4617402_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000003368 181.0
HFD3_k127_4617402_2 Zn peptidase K21686 - - 0.000000000000000000000002424 110.0
HFD3_k127_4617402_3 iron ion homeostasis - - - 0.000000000000000006713 96.0
HFD3_k127_4617402_5 Domain of unknown function (DUF4190) - - - 0.00005494 51.0
HFD3_k127_4630586_0 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 1.658e-217 685.0
HFD3_k127_4630586_1 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000009453 270.0
HFD3_k127_4630586_2 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.00000007531 53.0
HFD3_k127_4694779_0 amino acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 496.0
HFD3_k127_4694779_1 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005849 350.0
HFD3_k127_4695729_0 PFAM Aldehyde dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005066 458.0
HFD3_k127_4695729_1 BMC - - - 0.0000000000000000000000000000000000000226 147.0
HFD3_k127_4695729_2 Response regulator, receiver K11443 - - 0.00000000000000000000001042 104.0
HFD3_k127_4695729_3 von Willebrand factor, type A - - - 0.0000000000000174 84.0
HFD3_k127_4714766_0 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 488.0
HFD3_k127_4714766_1 Natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000302 282.0
HFD3_k127_4714766_2 PFAM thioesterase superfamily - - - 0.00000000000000000000000000005617 120.0
HFD3_k127_4714766_3 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000007272 87.0
HFD3_k127_4729108_0 Involved in the tonB-independent uptake of proteins K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004021 364.0
HFD3_k127_4729108_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009965 303.0
HFD3_k127_4729795_0 Thymidine kinase K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000005093 229.0
HFD3_k127_4729795_1 light absorption K06893 - - 0.000000000000000000000000000000009863 131.0
HFD3_k127_4731974_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 514.0
HFD3_k127_4731974_1 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004343 403.0
HFD3_k127_4731974_10 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001248 280.0
HFD3_k127_4731974_11 ZIP Zinc transporter K07238,K16267 - - 0.00000000000000000000000000000000000000000000000000000003342 206.0
HFD3_k127_4731974_12 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000007932 185.0
HFD3_k127_4731974_13 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000003876 171.0
HFD3_k127_4731974_14 - - - - 0.000000000000000000003498 94.0
HFD3_k127_4731974_15 Protein of unknown function (DUF3309) - - - 0.00000000000000006554 82.0
HFD3_k127_4731974_16 Essential cell division protein K03589 - - 0.0001013 53.0
HFD3_k127_4731974_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 389.0
HFD3_k127_4731974_3 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007545 353.0
HFD3_k127_4731974_4 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0030554,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 331.0
HFD3_k127_4731974_5 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 304.0
HFD3_k127_4731974_6 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 299.0
HFD3_k127_4731974_7 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005922 291.0
HFD3_k127_4731974_8 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000178 291.0
HFD3_k127_4731974_9 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006951 274.0
HFD3_k127_4739649_0 beta-fructofuranosidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000001484 224.0
HFD3_k127_4739649_1 GDSL-like Lipase/Acylhydrolase - - - 0.0002257 54.0
HFD3_k127_474030_0 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004524 348.0
HFD3_k127_474030_1 integral membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009171 305.0
HFD3_k127_474030_2 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 295.0
HFD3_k127_474030_3 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001955 261.0
HFD3_k127_474030_4 transcriptional regulator containing an HTH domain and an K03655 - 3.6.4.12 0.0000000000000000000000000000000000000369 159.0
HFD3_k127_474030_5 TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.000000000000000000000000000000008164 133.0
HFD3_k127_4746499_0 creatininase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003892 394.0
HFD3_k127_4746499_1 MgsA AAA+ ATPase C terminal K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005972 383.0
HFD3_k127_4746499_2 Bacterial regulatory proteins, tetR family - - - 0.0000000000006883 76.0
HFD3_k127_4747257_0 Elongation factor G, domain IV K02355 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 621.0
HFD3_k127_4747257_1 Beta-lactamase K17836 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001251 275.0
HFD3_k127_4747257_2 Protein of unknown function (DUF2911) - - - 0.0000000000000000000000000000000000000000000001227 180.0
HFD3_k127_4748843_0 amino acid - - - 4.495e-241 762.0
HFD3_k127_4748843_1 PFAM Peptidase S10, serine carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 429.0
HFD3_k127_4748843_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 408.0
HFD3_k127_4748843_3 Integral membrane protein TerC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 330.0
HFD3_k127_4748843_4 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006575 276.0
HFD3_k127_4748843_5 cAMP phosphodiesterases class-II - - - 0.0000000000000000000000000000000000000000005798 168.0
HFD3_k127_4748843_6 Probable zinc-ribbon domain - - - 0.000000000000000000000007932 105.0
HFD3_k127_4748843_7 Dienelactone hydrolase family - - - 0.000000000006238 76.0
HFD3_k127_4748843_8 polysaccharide export protein K01991 - - 0.00000000009395 74.0
HFD3_k127_4748843_9 protein import - - - 0.0000000006043 71.0
HFD3_k127_4766211_0 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 574.0
HFD3_k127_4766211_1 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000001061 194.0
HFD3_k127_4766211_2 ribose 5-phosphate isomerase B K00761,K01808 - 2.4.2.9,5.3.1.6 0.00000000000000000000000000000000003705 144.0
HFD3_k127_4766211_3 Domain of unknown function (DUF305) - - - 0.000000000000000000000000000000006089 135.0
HFD3_k127_4766211_4 von Willebrand factor, type A - - - 0.000000000000000000005329 106.0
HFD3_k127_4766211_5 - - - - 0.0000006494 56.0
HFD3_k127_4766211_6 - - - - 0.000004001 54.0
HFD3_k127_4770372_0 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 2.537e-286 897.0
HFD3_k127_4770372_1 Belongs to the glycosyl hydrolase 32 family K00692 - 2.4.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000006848 268.0
HFD3_k127_4770372_2 Putative methyltransferase K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.000000000000000000000000000000000000000000000000000000000000000001834 232.0
HFD3_k127_4770372_3 dextransucrase activity - - - 0.000000000000000000000000000000000000000000000000000004629 209.0
HFD3_k127_4770372_4 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.0000000000000000000000000000008207 126.0
HFD3_k127_4770372_6 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000002427 71.0
HFD3_k127_4770372_7 Rhomboid family - - - 0.00002038 50.0
HFD3_k127_4770372_8 Hydrolase CocE NonD family K06978 - - 0.0006263 50.0
HFD3_k127_4773791_0 COG0308 Aminopeptidase N - - - 2.54e-282 885.0
HFD3_k127_4773791_1 Heat shock 70 kDa protein K04043 - - 2.17e-233 736.0
HFD3_k127_4773791_2 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009607 439.0
HFD3_k127_4773791_3 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 426.0
HFD3_k127_4773791_4 DnaJ central domain K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002807 416.0
HFD3_k127_4773791_5 Yqey-like protein K09117 - - 0.0000000000000000000000000000000001427 138.0
HFD3_k127_4773791_6 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000005656 113.0
HFD3_k127_4773791_7 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.0000000000000002395 79.0
HFD3_k127_4782142_0 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005325 273.0
HFD3_k127_4782142_1 tail specific protease K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000007408 241.0
HFD3_k127_4782142_2 PFAM Cytochrome c assembly protein - - - 0.00000000000000000000000000000000000000000000000002948 198.0
HFD3_k127_4782142_3 Acetyltransferase (GNAT) domain K18816 - 2.3.1.82 0.00000000000000000000000000000000009997 138.0
HFD3_k127_4782142_4 PFAM ResB family protein K07399 - - 0.000000000000000000000000000000002234 146.0
HFD3_k127_4789010_0 Carboxypeptidase regulatory-like domain - - - 1.415e-253 822.0
HFD3_k127_4789010_1 COG3119 Arylsulfatase A and related enzymes K01137 - 3.1.6.14 0.0000000000000000000000000000000000000000000000008053 183.0
HFD3_k127_4789010_2 helix_turn _helix lactose operon repressor - - - 0.00000000000000000000000004088 110.0
HFD3_k127_4789185_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009993 309.0
HFD3_k127_4789185_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000007624 158.0
HFD3_k127_4793564_0 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 295.0
HFD3_k127_4793564_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006386 298.0
HFD3_k127_4793564_2 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000009801 271.0
HFD3_k127_4793564_3 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000000000003021 208.0
HFD3_k127_4798253_0 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005182 364.0
HFD3_k127_4798253_1 Oxidoreductase domain protein - - - 0.0000000000000000000000000000000003387 134.0
HFD3_k127_4811152_0 Holliday junction DNA helicase ruvB C-terminus K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 448.0
HFD3_k127_4811152_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000826 223.0
HFD3_k127_4811152_2 CAAX protease self-immunity - - - 0.00000000000000000000000000000000000000000000000000000000129 211.0
HFD3_k127_4811152_3 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000001958 175.0
HFD3_k127_4811152_4 four-way junction helicase activity K03550 GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.0000000000000000000000000000009036 125.0
HFD3_k127_4811152_5 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.000001084 61.0
HFD3_k127_482500_0 cytochrome C peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008801 244.0
HFD3_k127_482500_1 Domain of unknown function (DUF5122) beta-propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000001323 254.0
HFD3_k127_482500_2 Belongs to the glycosyl hydrolase 32 family K00692 - 2.4.1.10 0.0000000000000000000000000000000000000000001008 181.0
HFD3_k127_4835175_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0 2425.0
HFD3_k127_4835175_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 503.0
HFD3_k127_4835175_2 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.000000000000000000000000000000000000001371 151.0
HFD3_k127_4835175_3 TIGRFAM thioredoxin K03672 - 1.8.1.8 0.000000000000000000000000000000000000001418 151.0
HFD3_k127_4835175_4 MaoC like domain - - - 0.0000000000000000000000000000000000005045 143.0
HFD3_k127_4835175_5 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.00000000000000000000000000000002594 126.0
HFD3_k127_4835175_7 Cellulase (glycosyl hydrolase family 5) K19355 - 3.2.1.78 0.0005303 44.0
HFD3_k127_4839766_0 domain, Protein K01212,K12287,K20276 - 3.2.1.65 0.000000000000000000000000000000000000000000000000000000007496 216.0
HFD3_k127_4839766_1 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000001869 131.0
HFD3_k127_4839766_2 SdpI/YhfL protein family - - - 0.000000000001126 72.0
HFD3_k127_4839766_3 - - - - 0.000000008705 63.0
HFD3_k127_4860613_0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008154 544.0
HFD3_k127_4860613_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 528.0
HFD3_k127_4860613_2 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 409.0
HFD3_k127_4860613_3 TIGRFAM VWFA-related Acidobacterial domain - - - 0.0000000000000000000000000000314 131.0
HFD3_k127_4866134_0 Response receiver-modulated cyclic diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003664 252.0
HFD3_k127_4866134_1 Belongs to the glycosyl hydrolase 32 family K00692 - 2.4.1.10 0.000000000000000000000000000000000000000000000000000000000000000000012 241.0
HFD3_k127_4866134_2 - - - - 0.000000000003121 71.0
HFD3_k127_4872181_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 6.919e-200 634.0
HFD3_k127_4872181_1 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 301.0
HFD3_k127_4872181_2 Belongs to the short-chain dehydrogenases reductases (SDR) family K14189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 291.0
HFD3_k127_4872181_3 7TM receptor with intracellular metal dependent phosphohydrolase K07037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 311.0
HFD3_k127_4872181_4 Haemolysin-III related K11068 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001352 245.0
HFD3_k127_4872181_5 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000006455 220.0
HFD3_k127_4872181_6 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000331 94.0
HFD3_k127_4874099_0 Belongs to the CinA family K03742 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000009389 218.0
HFD3_k127_4874099_1 Belongs to the GSP D family K02453 - - 0.000000000000000000000000000000000000000001478 179.0
HFD3_k127_4874099_2 Prokaryotic N-terminal methylation motif K02456 - - 0.00000000000000000000002806 108.0
HFD3_k127_4874099_3 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000002016 89.0
HFD3_k127_4882369_0 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000105 308.0
HFD3_k127_4882369_1 response regulator - - - 0.0000000000000000000000000000000000000000000000000000003944 200.0
HFD3_k127_4882369_2 WD40-like Beta Propeller Repeat K03641 - - 0.0000000000000000000000000000000000000000001505 172.0
HFD3_k127_4882369_3 cellulase activity K20276 - - 0.000000000000000000000000000000000001762 156.0
HFD3_k127_4886841_0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal K00457 - 1.13.11.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007475 523.0
HFD3_k127_4886841_1 tryptophan K00500 GO:0000003,GO:0001505,GO:0003008,GO:0003674,GO:0003824,GO:0004497,GO:0004505,GO:0004510,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006082,GO:0006464,GO:0006520,GO:0006558,GO:0006559,GO:0006568,GO:0006569,GO:0006570,GO:0006571,GO:0006576,GO:0006582,GO:0006584,GO:0006586,GO:0006725,GO:0006726,GO:0006732,GO:0006807,GO:0006950,GO:0006979,GO:0007275,GO:0007568,GO:0007610,GO:0007611,GO:0007613,GO:0007616,GO:0008150,GO:0008152,GO:0008340,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009072,GO:0009073,GO:0009074,GO:0009095,GO:0009308,GO:0009310,GO:0009712,GO:0009713,GO:0009987,GO:0010259,GO:0016053,GO:0016054,GO:0016491,GO:0016597,GO:0016705,GO:0016714,GO:0017144,GO:0018126,GO:0018958,GO:0019438,GO:0019439,GO:0019538,GO:0019748,GO:0019751,GO:0019752,GO:0031406,GO:0032501,GO:0032502,GO:0034311,GO:0034641,GO:0036094,GO:0036211,GO:0040002,GO:0042133,GO:0042136,GO:0042335,GO:0042402,GO:0042423,GO:0042430,GO:0042436,GO:0042438,GO:0042440,GO:0042441,GO:0042558,GO:0042737,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043324,GO:0043412,GO:0043436,GO:0043473,GO:0043474,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044270,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046146,GO:0046148,GO:0046189,GO:0046218,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0046983,GO:0048037,GO:0048066,GO:0048069,GO:0048856,GO:0050877,GO:0050890,GO:0050896,GO:0051186,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901615,GO:1901617,GO:1902221,GO:1902222 1.14.16.1 0.0000000000000000000000000000000000000000000000000000000000000000001624 238.0
HFD3_k127_4886841_2 Phosphoenolpyruvate phosphomutase - - - 0.000000000000000000000000000000000000000000000000000000000565 205.0
HFD3_k127_4886841_3 RibD C-terminal domain K00287 - 1.5.1.3 0.00000000000000000000000000000000000000000000000000001843 194.0
HFD3_k127_4886841_4 -acetyltransferase - - - 0.000000000000000000000000000000000000000000004497 166.0
HFD3_k127_4898139_0 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000007192 241.0
HFD3_k127_4898139_1 Belongs to the MlaE permease family K02066 - - 0.000000000000000000000000000000000000000000000000000000000000003194 226.0
HFD3_k127_4898139_2 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000003866 186.0
HFD3_k127_4898139_3 Mo-molybdopterin cofactor biosynthetic process - - - 0.00000000000000000000000000000000000002737 151.0
HFD3_k127_4898139_4 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000009358 149.0
HFD3_k127_4898139_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000005248 126.0
HFD3_k127_4898139_6 Regulates arginine biosynthesis genes K03402 - - 0.000000000000000000001623 99.0
HFD3_k127_4898139_7 Heavy-metal resistance - - - 0.00008035 51.0
HFD3_k127_4905841_0 tetratricopeptide - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000355 505.0
HFD3_k127_4905841_1 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008835 394.0
HFD3_k127_4905841_10 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000002696 130.0
HFD3_k127_4905841_11 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000001709 117.0
HFD3_k127_4905841_12 Tetratricopeptide repeat - - - 0.0000000000000000000000001156 121.0
HFD3_k127_4905841_13 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.00002293 57.0
HFD3_k127_4905841_2 glycosyl transferase group 1 K00754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 401.0
HFD3_k127_4905841_3 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 353.0
HFD3_k127_4905841_4 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 323.0
HFD3_k127_4905841_5 neuron death in response to oxidative stress K01173,K07004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002926 326.0
HFD3_k127_4905841_6 alpha beta - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001788 260.0
HFD3_k127_4905841_7 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000003839 229.0
HFD3_k127_4905841_8 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000003944 154.0
HFD3_k127_4905841_9 Plasmid stabilization - - - 0.0000000000000000000000000000004837 123.0
HFD3_k127_4908184_0 SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556 K00239 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0022900,GO:0044237,GO:0045333,GO:0055114 1.3.5.1,1.3.5.4 3.388e-250 783.0
HFD3_k127_4908184_1 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 309.0
HFD3_k127_4910834_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 4.932e-253 797.0
HFD3_k127_4910834_1 Elongation factor SelB, winged helix K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003269 461.0
HFD3_k127_4910834_2 Belongs to the FGGY kinase family K00851 - 2.7.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 381.0
HFD3_k127_4910834_3 two component, sigma54 specific, transcriptional regulator, Fis family K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 323.0
HFD3_k127_4910834_4 Putative serine dehydratase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005831 299.0
HFD3_k127_4910834_5 Protein of unknown function (DUF962) - - - 0.000000000000000000000000000000000001496 142.0
HFD3_k127_4910834_6 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.0000000000000000000000000005946 119.0
HFD3_k127_4910834_7 Protein of unknown function (DUF2442) - - - 0.0000000000000000001908 89.0
HFD3_k127_4920525_0 Belongs to the glycosyl hydrolase 32 family K00692 - 2.4.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001113 295.0
HFD3_k127_4920525_1 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004186 274.0
HFD3_k127_4920525_2 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000006526 272.0
HFD3_k127_4920525_3 Belongs to the UPF0234 family K09767 - - 0.000000000000000000000000000000000000000000000000000000007678 202.0
HFD3_k127_4920525_4 Protease prsW family - - - 0.0000000000000000000000006309 116.0
HFD3_k127_4920525_5 Zinc metalloprotease (Elastase) - - - 0.00000000000007036 85.0
HFD3_k127_4920525_7 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000001252 63.0
HFD3_k127_4935179_0 Tricorn protease C1 domain K08676 - - 2.922e-244 775.0
HFD3_k127_4935179_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000001835 195.0
HFD3_k127_4953675_0 PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 - 3.4.21.83 6.884e-202 651.0
HFD3_k127_4953675_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000003982 186.0
HFD3_k127_4971526_0 Penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 453.0
HFD3_k127_4971526_1 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000004191 76.0
HFD3_k127_4973022_0 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005137 269.0
HFD3_k127_4973022_1 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000001338 233.0
HFD3_k127_4973022_2 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000008717 80.0
HFD3_k127_4973022_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000001359 82.0
HFD3_k127_4973022_4 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.000000001022 61.0
HFD3_k127_4979537_0 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000001472 130.0
HFD3_k127_4979537_1 lysine biosynthetic process via aminoadipic acid - - - 0.000000001834 69.0
HFD3_k127_4986904_0 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000001019 178.0
HFD3_k127_4986904_1 Belongs to the SEDS family K03588 GO:0002682,GO:0002684,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136 - 0.000000000000000000000000000000000000002357 166.0
HFD3_k127_4986904_2 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 0.000000000000000000000000000000000002243 140.0
HFD3_k127_4986904_3 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.00000000000000000000000000004989 127.0
HFD3_k127_5003728_0 Glutamate synthase K17722 - 1.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 403.0
HFD3_k127_5003728_1 TIGRFAM Dihydroorotate dehydrogenase K17723 - 1.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006652 286.0
HFD3_k127_5003728_2 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000001532 149.0
HFD3_k127_5018089_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 6.761e-225 718.0
HFD3_k127_5018089_1 MotA TolQ ExbB proton channel K03561,K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001129 246.0
HFD3_k127_5018089_2 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000000000000002987 169.0
HFD3_k127_5018089_3 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.0000000000000000000000004053 110.0
HFD3_k127_5018089_4 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000000003229 104.0
HFD3_k127_5018089_5 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.000000000000000007649 89.0
HFD3_k127_5018089_6 Peptidylprolyl isomerase K03771 - 5.2.1.8 0.000000001824 66.0
HFD3_k127_5018089_7 BlaR1 peptidase M56 - - - 0.00004167 49.0
HFD3_k127_5018089_8 Tetratricopeptide repeat - - - 0.00004561 55.0
HFD3_k127_50505_0 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 417.0
HFD3_k127_50505_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000002712 229.0
HFD3_k127_50505_2 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000000000000000000007982 190.0
HFD3_k127_50505_3 Glycosyltransferase family 28 N-terminal domain - - - 0.000000000000000000000000000000000000000000000001241 181.0
HFD3_k127_5051702_0 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 440.0
HFD3_k127_5051702_1 Protein of unknown function (DUF512) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 306.0
HFD3_k127_5051702_2 energy transducer activity K03832 - - 0.00000000001528 68.0
HFD3_k127_5078276_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000000000005147 199.0
HFD3_k127_5078276_1 - - - - 0.0000000000000009907 87.0
HFD3_k127_5078276_2 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000008142 63.0
HFD3_k127_5078276_3 - - - - 0.0000007219 55.0
HFD3_k127_5083521_0 radical SAM domain protein K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 375.0
HFD3_k127_5083521_1 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007333 337.0
HFD3_k127_5083521_2 arginyltransferase activity K21420 GO:0003674,GO:0003824,GO:0004057,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016598,GO:0016740,GO:0016746,GO:0016755,GO:0019538,GO:0019941,GO:0030163,GO:0036211,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 2.3.2.29 0.000000000000000000000000000000000000000000000000000000005324 206.0
HFD3_k127_5083521_3 UPF0126 domain - - - 0.0000000000000000000000000000000000000000000007749 173.0
HFD3_k127_5083521_4 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000009785 143.0
HFD3_k127_5083521_5 Protein of unknown function (DUF2721) - - - 0.00000000000000000000007324 106.0
HFD3_k127_5083521_6 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.0000000000000000000006507 98.0
HFD3_k127_508506_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003322 531.0
HFD3_k127_508506_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075,K15780 - 2.4.2.8,6.3.4.19 0.00000000000000000178 90.0
HFD3_k127_5088137_0 HELICc2 K03722 - 3.6.4.12 6.33e-201 645.0
HFD3_k127_5088137_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000005264 220.0
HFD3_k127_5088137_2 Zinc metalloprotease (Elastase) K20274 - - 0.0000000000000000000000000000000000000000000000000000000001014 224.0
HFD3_k127_5088137_3 SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000002468 195.0
HFD3_k127_5088137_4 Putative lumazine-binding - - - 0.00000000000000000000000000000000000000007408 156.0
HFD3_k127_5088137_5 PFAM 6-pyruvoyl tetrahydropterin K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000008927 131.0
HFD3_k127_5088137_6 TIGRFAM TonB-dependent heme hemoglobin receptor family protein K02014,K16087 - - 0.0000000000000000000000001346 124.0
HFD3_k127_5088301_0 Carboxyl transferase domain - - - 6.385e-214 674.0
HFD3_k127_5088301_1 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003369 479.0
HFD3_k127_5088301_2 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008266 353.0
HFD3_k127_5088301_3 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004606 281.0
HFD3_k127_5088301_4 EVE domain - - - 0.00000000000000000000000000000000000000000000008817 173.0
HFD3_k127_5091703_0 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 415.0
HFD3_k127_5091703_1 pyrroloquinoline quinone binding - - - 0.00000000000000000000000000000000000000000000000026 184.0
HFD3_k127_5101562_0 NapC/NirT cytochrome c family, N-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 526.0
HFD3_k127_5101562_1 Cytochrome c7 and related cytochrome c - - - 0.0000000000005135 79.0
HFD3_k127_510985_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01751,K01754,K06016,K17989,K21400 GO:0000287,GO:0003674,GO:0003824,GO:0003941,GO:0004793,GO:0004794,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0006082,GO:0006090,GO:0006464,GO:0006520,GO:0006549,GO:0006563,GO:0006565,GO:0006566,GO:0006567,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008838,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009071,GO:0009081,GO:0009082,GO:0009097,GO:0009987,GO:0016020,GO:0016053,GO:0016054,GO:0016597,GO:0016829,GO:0016830,GO:0016832,GO:0016840,GO:0016841,GO:0016853,GO:0016854,GO:0016855,GO:0017144,GO:0018249,GO:0019538,GO:0019752,GO:0019842,GO:0030170,GO:0030378,GO:0030848,GO:0031406,GO:0032787,GO:0036094,GO:0036211,GO:0036361,GO:0042219,GO:0042802,GO:0042803,GO:0042866,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046416,GO:0046437,GO:0046872,GO:0046983,GO:0047661,GO:0048037,GO:0050662,GO:0070178,GO:0070179,GO:0070279,GO:0071704,GO:0071944,GO:0072330,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.3.1.263,3.5.1.6,3.5.1.87,4.3.1.15,4.3.1.17,4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 379.0
HFD3_k127_510985_1 Protein of unknown function (DUF1211) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003134 280.0
HFD3_k127_510985_2 phosphorelay signal transduction system K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000004027 231.0
HFD3_k127_510985_3 Transglycosylase associated protein - - - 0.0000000000000009872 80.0
HFD3_k127_510985_4 Hemerythrin HHE cation binding domain - - - 0.000000005262 59.0
HFD3_k127_510985_5 Periplasmic or secreted lipoprotein - - - 0.000001435 61.0
HFD3_k127_5132553_0 Prolyl oligopeptidase family - - - 1.786e-197 635.0
HFD3_k127_5132553_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 465.0
HFD3_k127_5132553_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 299.0
HFD3_k127_5132553_3 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000188 204.0
HFD3_k127_5132553_4 Phosphoribosyl transferase domain K00762 - 2.4.2.10 0.000000000000000000000000000000000000005051 153.0
HFD3_k127_5132553_5 Belongs to the Nudix hydrolase family - - - 0.0000000000001171 78.0
HFD3_k127_5132553_6 - - - - 0.000000000002551 73.0
HFD3_k127_5160074_0 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008376 368.0
HFD3_k127_5160074_1 cellulose binding K13735 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 336.0
HFD3_k127_5160074_2 Belongs to the glycosyl hydrolase 32 family K00692 - 2.4.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000001848 270.0
HFD3_k127_5209180_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 1.137e-229 728.0
HFD3_k127_5209180_1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007421 293.0
HFD3_k127_5209180_2 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000000002043 161.0
HFD3_k127_5209180_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000005845 149.0
HFD3_k127_5209180_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000006093 126.0
HFD3_k127_5229540_0 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008618 429.0
HFD3_k127_5229540_1 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001487 269.0
HFD3_k127_5229540_2 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.0000000000000000000000000000004601 126.0
HFD3_k127_5229540_3 COG2755 Lysophospholipase L1 and related K10804 - 3.1.1.5 0.00002435 51.0
HFD3_k127_5233796_0 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004536 595.0
HFD3_k127_5233796_1 class II (D K K01893 - 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008935 585.0
HFD3_k127_5233796_2 proteins of the AP superfamily K01113 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007583 383.0
HFD3_k127_5233796_3 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000001618 228.0
HFD3_k127_5233796_4 protein secretion by the type I secretion system K11085 - - 0.0000000000000000000000000000000000000000000000000007568 187.0
HFD3_k127_5233796_5 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.00000000000000000000000000000000000000000000000009954 189.0
HFD3_k127_5255617_0 aminopeptidase activity K01301 - 3.4.17.21 2.019e-283 886.0
HFD3_k127_5255617_1 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000229 244.0
HFD3_k127_5255617_2 - - - - 0.000000000000000000000000000000000000000001884 160.0
HFD3_k127_5255617_3 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.00003703 55.0
HFD3_k127_5256341_0 Belongs to the 'phage' integrase family K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001624 270.0
HFD3_k127_5256341_1 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000000000000000000000000000003769 226.0
HFD3_k127_5256341_2 Hemerythrin HHE cation binding K07322 - - 0.000000000000000000000000000000000000005704 153.0
HFD3_k127_5256341_3 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000724 81.0
HFD3_k127_5256471_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 6.791e-279 873.0
HFD3_k127_5256471_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 3.8e-204 657.0
HFD3_k127_5256471_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000001568 219.0
HFD3_k127_5256471_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.00000000000000000000000000000000000000000000000000000000000008211 216.0
HFD3_k127_5256471_4 - - - - 0.0000000000000000000000000000000000002373 154.0
HFD3_k127_5256471_5 Ferredoxin K00529,K04755,K08952,K08953,K08954,K15765 GO:0005575,GO:0005622,GO:0005623,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0046858 1.18.1.3 0.00000000000000000000000000000617 132.0
HFD3_k127_5256471_6 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000002099 81.0
HFD3_k127_5256471_7 Protein-tyrosine phosphatase - - - 0.00000000007124 66.0
HFD3_k127_5256471_8 Domain of unknown function (DUF4956) - - - 0.00000000009335 72.0
HFD3_k127_5318550_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008262 526.0
HFD3_k127_5318550_1 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 416.0
HFD3_k127_5335688_0 cAMP biosynthetic process K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 423.0
HFD3_k127_5336110_0 ketoglutarate semialdehyde dehydrogenase K14519 - 1.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 567.0
HFD3_k127_5336110_1 Dihydrodipicolinate synthetase family K21062 - 3.5.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 346.0
HFD3_k127_5336110_2 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 335.0
HFD3_k127_5336110_3 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000000000000000006271 181.0
HFD3_k127_5336110_4 - - - - 0.00000000000000000000005019 104.0
HFD3_k127_5337747_0 acyl-coa dehydrogenase K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 535.0
HFD3_k127_5337747_1 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008913 334.0
HFD3_k127_5337747_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000006715 226.0
HFD3_k127_5337747_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000002087 151.0
HFD3_k127_5337747_4 Belongs to the glycosyl hydrolase 32 family K00692 - 2.4.1.10 0.00000000000000000000000007695 109.0
HFD3_k127_5337747_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K07027 - - 0.0000005365 61.0
HFD3_k127_5340916_0 amino acid K20265 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0006873,GO:0006885,GO:0008150,GO:0008509,GO:0008514,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0019725,GO:0022804,GO:0022857,GO:0030003,GO:0030004,GO:0030641,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0045852,GO:0046942,GO:0046943,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0051454,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:0098771,GO:1902475,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 494.0
HFD3_k127_5340916_1 domain, Protein K21449 - - 0.00000000000000000007935 102.0
HFD3_k127_5370259_0 PFAM Na-Ca exchanger integrin-beta4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 406.0
HFD3_k127_5370259_1 Belongs to the glycosyl hydrolase 32 family K00692 - 2.4.1.10 0.000000000000000000000000000000000000000000000000000000001293 230.0
HFD3_k127_5370259_2 peptidyl-prolyl cis-trans isomerase activity K00645,K01802,K02597,K03769,K03770,K03771 - 2.3.1.39,5.2.1.8 0.0000002808 60.0
HFD3_k127_5389135_0 Domain of unknown function (DUF1929) K04618 - 1.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 428.0
HFD3_k127_5389135_1 CHRD domain - - - 0.000000000000000000000000000005995 124.0
HFD3_k127_5389135_2 PFAM Hemolysin-type calcium-binding region - - - 0.000000006145 65.0
HFD3_k127_5396457_0 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.0000000000000000000000000005556 125.0
HFD3_k127_5396457_1 ompA family - - - 0.00000000004145 74.0
HFD3_k127_5397480_0 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 488.0
HFD3_k127_5397480_1 methyltransferase activity K00569 - 2.1.1.67 0.0000000000000000000000000000000000000000000000000000000001311 210.0
HFD3_k127_5397480_2 SMART Rhodanese domain protein - - - 0.00000000000000000000000000000000000000000001289 168.0
HFD3_k127_5397480_3 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000001823 162.0
HFD3_k127_5397480_4 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000001985 103.0
HFD3_k127_5397480_5 Regulatory protein ArsR - - - 0.00000000000000000000006441 101.0
HFD3_k127_5430404_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 2.53e-199 633.0
HFD3_k127_5430404_1 Amidase K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003666 514.0
HFD3_k127_5430404_10 - - - - 0.0009726 42.0
HFD3_k127_5430404_2 Substrate-binding region of ABC-type glycine betaine transport system K05845,K05846 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 438.0
HFD3_k127_5430404_3 AhpC/TSA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 300.0
HFD3_k127_5430404_4 protease with the C-terminal PDZ domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005541 306.0
HFD3_k127_5430404_5 SMART ATPase, AAA type, core K05847 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004213 286.0
HFD3_k127_5430404_6 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000003943 163.0
HFD3_k127_5430404_7 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000001794 158.0
HFD3_k127_5430404_8 ErfK YbiS YcfS YnhG family protein - - - 0.0000000000000000000000000000000000000004181 157.0
HFD3_k127_5430404_9 Bacterial regulatory proteins, tetR family - - - 0.000000000000000002687 93.0
HFD3_k127_5435921_0 Domain of unknown function (DUF2088) - - - 6.815e-219 691.0
HFD3_k127_5435921_1 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008499 544.0
HFD3_k127_5435921_10 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000002442 107.0
HFD3_k127_5435921_11 Tetratricopeptide repeat - - - 0.0000000001065 72.0
HFD3_k127_5435921_2 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004531 337.0
HFD3_k127_5435921_3 PFAM Basic membrane lipoprotein K07335 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009653 297.0
HFD3_k127_5435921_4 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004464 245.0
HFD3_k127_5435921_5 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004598 244.0
HFD3_k127_5435921_6 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000001442 184.0
HFD3_k127_5435921_7 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000003148 172.0
HFD3_k127_5435921_8 S23 ribosomal protein - - - 0.000000000000000000000000000000000000000004691 158.0
HFD3_k127_5435921_9 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000000000000000173 153.0
HFD3_k127_5439373_0 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.0000000000000000000000000000000000000000000000002757 178.0
HFD3_k127_5439373_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000002006 143.0
HFD3_k127_5439373_2 Peptidylprolyl isomerase K03771 - 5.2.1.8 0.000000000000003209 89.0
HFD3_k127_5443913_0 Amidohydrolase K03392 - 4.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003505 471.0
HFD3_k127_5443913_1 cellulose binding - - - 0.000000000000000000000000000004891 130.0
HFD3_k127_5443913_2 Calcium/calmodulin dependent protein kinase II association domain - - - 0.0001823 50.0
HFD3_k127_5452594_0 Dienelactone hydrolase family - - - 1.23e-269 847.0
HFD3_k127_5452594_1 Alcohol dehydrogenase GroES-associated - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005454 579.0
HFD3_k127_5452594_2 PFAM beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 497.0
HFD3_k127_5452594_3 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007888 387.0
HFD3_k127_5452594_4 D-aminopeptidase K16203 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 334.0
HFD3_k127_5452594_5 Cobyrinic acid ac-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009947 264.0
HFD3_k127_5452594_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001206 253.0
HFD3_k127_5452594_7 chromosome segregation K03497 - - 0.00000000000000000000000000000000000000000000000009544 189.0
HFD3_k127_5452594_8 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000002786 160.0
HFD3_k127_5452594_9 - - - - 0.000000000000000000001573 103.0
HFD3_k127_5453187_0 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.000000000000000000000000000000000000000000000000000000000000000006421 233.0
HFD3_k127_5453187_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000001263 228.0
HFD3_k127_5453187_2 Beta-lactamase - - - 0.0000000000000000000000000000000000001368 147.0
HFD3_k127_5453187_3 - - - - 0.0000000000000000000000007363 110.0
HFD3_k127_5453187_4 Serine aminopeptidase, S33 K01055 - 3.1.1.24 0.00000000000001579 78.0
HFD3_k127_5456821_0 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003189 273.0
HFD3_k127_5456821_1 PFAM RecF RecN SMC N terminal domain K03546 - - 0.000000000000000000000000188 106.0
HFD3_k127_5456821_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000819 94.0
HFD3_k127_5483511_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 586.0
HFD3_k127_5483511_1 Myo-inositol-1-phosphate synthase GAPDH domain protein K01858 - 5.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 458.0
HFD3_k127_5483511_10 Sh3 type 3 domain protein - - - 0.0004736 52.0
HFD3_k127_5483511_2 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005369 396.0
HFD3_k127_5483511_3 NAD-dependent K08678 - 4.1.1.35 0.000000000000000000000000000000000000000000003594 166.0
HFD3_k127_5483511_5 Smr domain - - - 0.000000000000000000000000166 108.0
HFD3_k127_5483511_6 Tetratricopeptide repeat - - - 0.00000000000002752 74.0
HFD3_k127_5483511_8 Carboxypeptidase regulatory-like domain - - - 0.00001326 55.0
HFD3_k127_5483511_9 ERAP1-like C-terminal domain - GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005854,GO:0006417,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009056,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010608,GO:0016787,GO:0019222,GO:0019538,GO:0022613,GO:0031323,GO:0031326,GO:0032268,GO:0032991,GO:0033218,GO:0034248,GO:0034641,GO:0042254,GO:0042277,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0070006,GO:0070011,GO:0071704,GO:0071840,GO:0080090,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1990593,GO:2000112,GO:2000765 - 0.0003029 53.0
HFD3_k127_5487540_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000113 282.0
HFD3_k127_5487540_1 PFAM DNA RNA non-specific endonuclease K01173 - - 0.0000000000000000000000000000000000000000000000000000000000000002664 231.0
HFD3_k127_5487540_2 - - - - 0.000000000000000000000000000000000000000000000000000009579 194.0
HFD3_k127_5487540_3 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000887 198.0
HFD3_k127_5487540_4 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000005112 177.0
HFD3_k127_5487540_6 Disulphide bond corrector protein DsbC K04084,K06888 - 1.8.1.8 0.00000000000166 74.0
HFD3_k127_5503106_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 8.644e-242 767.0
HFD3_k127_5503106_1 'Xanthine and CO dehydrogenases maturation factor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 294.0
HFD3_k127_5503106_2 [2Fe-2S] binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001146 225.0
HFD3_k127_5503106_3 Transglycosylase SLT domain K08309 - - 0.0000000000000000000000000000000000000000000000000000001388 219.0
HFD3_k127_5503106_4 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.0000000000001072 77.0
HFD3_k127_5504637_0 PFAM phenylalanine histidine ammonia-lyase K01745 - 4.3.1.3 1.999e-214 681.0
HFD3_k127_5504637_1 PFAM amidohydrolase K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004242 445.0
HFD3_k127_5504637_2 tRNA (guanine(37)-N(1))-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005888 339.0
HFD3_k127_5504637_3 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.0000000000000000000000000000000000000000000000000001657 187.0
HFD3_k127_5504637_4 YCII-related domain - - - 0.0000000000000000000000000000000000000000007456 166.0
HFD3_k127_5504637_5 peptidase M15B and M15C DD-carboxypeptidase VanY - - - 0.000000000000000002145 96.0
HFD3_k127_5504637_6 ErfK ybiS ycfS ynhG family protein K16291 - - 0.000000000000006476 87.0
HFD3_k127_5506805_0 chorismate binding enzyme K01665,K02619,K03342,K13503,K13950 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.6.1.85,4.1.3.27,4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000482 589.0
HFD3_k127_5506805_1 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 304.0
HFD3_k127_5514782_0 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008372 586.0
HFD3_k127_5514782_1 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 472.0
HFD3_k127_5531233_0 Tricorn protease homolog - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009505 424.0
HFD3_k127_5531233_1 Penicillin amidase K07116 - 3.5.1.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 372.0
HFD3_k127_5531233_2 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000231 242.0
HFD3_k127_5531233_3 Transcriptional regulator - - - 0.000000000000000000000001385 115.0
HFD3_k127_5531233_4 - - - - 0.00000000000000002618 89.0
HFD3_k127_5534579_0 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008207 261.0
HFD3_k127_5534579_1 COG3209 Rhs family protein - - - 0.0005006 48.0
HFD3_k127_555601_0 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009662 393.0
HFD3_k127_555601_1 PFAM Transglycosylase SLT domain K08307 - - 0.000000000000000000000000000000000000000000000000000000001871 213.0
HFD3_k127_555601_2 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000007142 195.0
HFD3_k127_555601_3 Transcriptional regulator - - - 0.0000000000000000000000000000001239 128.0
HFD3_k127_555601_4 PFAM aldo keto reductase - - - 0.00000000000000000000000001027 111.0
HFD3_k127_5587480_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004901 471.0
HFD3_k127_5587480_1 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006698 465.0
HFD3_k127_5587480_2 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000008714 206.0
HFD3_k127_5587480_3 Biopterin-dependent aromatic amino acid hydroxylase - - - 0.00000000000000000000000000000000000000002316 160.0
HFD3_k127_5587480_4 PFAM Bacterial regulatory proteins, luxR family - - - 0.000000000000000000000000000000000002239 141.0
HFD3_k127_5587480_5 Protein of unknown function (DUF4199) - - - 0.00000000000000000000000000000000001858 141.0
HFD3_k127_5587480_6 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000000000474 75.0
HFD3_k127_5587480_7 metallocarboxypeptidase activity K07752 GO:0006937,GO:0008150,GO:0044057,GO:0050789,GO:0051239,GO:0065007,GO:0090257 3.4.17.22 0.0003825 52.0
HFD3_k127_5599856_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 563.0
HFD3_k127_5599856_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616,K08314 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 299.0
HFD3_k127_5599856_10 Protein of unknown function (DUF402) K07586 - - 0.000000000000001273 86.0
HFD3_k127_5599856_11 PA14 domain - - - 0.000000000000009386 86.0
HFD3_k127_5599856_12 histone H2A K63-linked ubiquitination - - - 0.0000004783 61.0
HFD3_k127_5599856_13 N-terminal region of micro-spherule protein K11674 - - 0.0000187 56.0
HFD3_k127_5599856_2 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003304 277.0
HFD3_k127_5599856_3 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000007215 239.0
HFD3_k127_5599856_4 Psort location CytoplasmicMembrane, score K12132 - 2.7.11.1 0.0000000000000000000000000006817 129.0
HFD3_k127_5599856_5 Iron dependent repressor, N-terminal DNA binding domain - - - 0.00000000000000000000001505 105.0
HFD3_k127_5599856_6 cheY-homologous receiver domain K11443 - - 0.0000000000000000000002271 101.0
HFD3_k127_5599856_7 Universal stress protein family - - - 0.000000000000000000002371 99.0
HFD3_k127_5599856_8 penicillin-binding protein - - - 0.0000000000000000000293 102.0
HFD3_k127_5599856_9 - - - - 0.00000000000000000004592 94.0
HFD3_k127_5608978_0 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 578.0
HFD3_k127_5608978_1 NAD(P)-binding Rossmann-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003356 474.0
HFD3_k127_5608978_2 Domain of unknown function (DUF4178) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004982 456.0
HFD3_k127_5608978_3 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 357.0
HFD3_k127_5608978_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000007825 157.0
HFD3_k127_5608978_5 S-adenosylmethionine decarboxylase K01611 - 4.1.1.50 0.00000000000000000000000000000000008749 136.0
HFD3_k127_5608978_6 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000001286 144.0
HFD3_k127_5608978_7 - - - - 0.00000000000000000000000000000001846 135.0
HFD3_k127_5608978_8 Domain of Unknown Function (DUF350) - - - 0.00000000000001189 77.0
HFD3_k127_5616781_0 Methionine synthase B12-binding module cap domain protein K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.0 1343.0
HFD3_k127_5616781_1 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004899 404.0
HFD3_k127_5616781_2 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000001364 182.0
HFD3_k127_5616781_3 Forkhead associated domain - - - 0.00000000000000000000000000000000000001606 163.0
HFD3_k127_5617600_0 Dienelactone hydrolase family - - - 9.439e-281 883.0
HFD3_k127_5617600_1 Cation transport regulator - - - 0.0000000000000000000000000000000000000000000000000000000000236 211.0
HFD3_k127_5617600_2 Belongs to the UPF0102 family K07460 - - 0.000000000000001473 85.0
HFD3_k127_5617600_3 iron-regulated protein - - - 0.0000000000002219 72.0
HFD3_k127_5622785_0 TIGRFAM PQQ-dependent dehydrogenase, methanol ethanol family K00114 - 1.1.2.8 6.641e-276 859.0
HFD3_k127_5622785_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 9.784e-244 769.0
HFD3_k127_5622785_2 cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009498 308.0
HFD3_k127_5622785_3 SMART Extracellular solute-binding protein, family 3 K16254 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001508 278.0
HFD3_k127_5622785_4 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.00000000000000000000000000000000000000000000003017 175.0
HFD3_k127_5622785_5 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) K02351 - - 0.00000000000000000000000000000000000001484 154.0
HFD3_k127_5622785_6 Cytochrome c oxidase subunit III - - - 0.00000000000000000000000000000001057 138.0
HFD3_k127_5635467_0 Rossmann-like domain - - - 0.00000000000000000000000000000000001703 146.0
HFD3_k127_5635467_1 Belongs to the Fur family K03711 - - 0.0000000000000000000000006439 107.0
HFD3_k127_5639420_0 amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007357 314.0
HFD3_k127_5639420_1 Histidine kinase K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000554 163.0
HFD3_k127_5642395_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000507 286.0
HFD3_k127_5642395_1 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000007167 197.0
HFD3_k127_5642395_3 Antibiotic biosynthesis monooxygenase K11530 - 5.3.1.32 0.0000003758 55.0
HFD3_k127_5670999_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.000000000000000000000000000000009744 128.0
HFD3_k127_5670999_1 Predicted membrane protein (DUF2085) - - - 0.00000000000000000000001375 108.0
HFD3_k127_5670999_2 - - - - 0.00001554 50.0
HFD3_k127_5683749_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 606.0
HFD3_k127_5683749_1 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004362 591.0
HFD3_k127_5683749_2 Cupin domain - - - 0.000000008018 62.0
HFD3_k127_5683749_3 hyperosmotic response - - - 0.0001872 48.0
HFD3_k127_5685330_0 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000006978 165.0
HFD3_k127_5685330_1 O-antigen ligase like membrane protein - - - 0.0000000005662 72.0
HFD3_k127_5685330_2 Carboxylesterase K06999 - - 0.000000005677 66.0
HFD3_k127_5685330_3 PFAM YbbR family protein - - - 0.00005907 53.0
HFD3_k127_571798_0 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000003638 247.0
HFD3_k127_571798_1 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000002366 170.0
HFD3_k127_571798_2 COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family K16048 - - 0.000000000000000000000000000000000000000001231 161.0
HFD3_k127_571798_3 - - - - 0.00000001203 56.0
HFD3_k127_571798_4 Involved in the tonB-independent uptake of proteins - - - 0.00001012 54.0
HFD3_k127_5735171_0 CarboxypepD_reg-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 535.0
HFD3_k127_5742011_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 4.397e-231 724.0
HFD3_k127_5742011_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 391.0
HFD3_k127_5742011_2 ADP-ribosylation factor family K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 316.0
HFD3_k127_5742011_3 Required for morphogenesis under gluconeogenic growth conditions - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005365 316.0
HFD3_k127_5742011_4 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000004636 220.0
HFD3_k127_5742011_5 PFAM Roadblock LC7 family protein - - - 0.0000000000000000000000000000000000004817 145.0
HFD3_k127_5755597_0 aldehyde oxidase and xanthine dehydrogenase a b hammerhead K13482 - 1.17.1.4 0.0 1048.0
HFD3_k127_5755597_1 CO dehydrogenase flavoprotein C-terminal domain K13481 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 463.0
HFD3_k127_5755597_2 PLD-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 462.0
HFD3_k127_5755597_3 XdhC Rossmann domain K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005764 277.0
HFD3_k127_5755597_4 Glutamine cyclotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009603 257.0
HFD3_k127_5755597_5 Cytidine and deoxycytidylate deaminase zinc-binding region K01487 - 3.5.4.3 0.000000000000000000000000000000000000000000000000000000000003292 213.0
HFD3_k127_5755597_6 Putative inner membrane exporter, YdcZ K09936 - - 0.00000000000000000000000000000000003141 139.0
HFD3_k127_5755597_7 DSBA-like thioredoxin domain K21990 - - 0.0000000002008 64.0
HFD3_k127_5758930_0 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 376.0
HFD3_k127_5758930_1 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000001301 147.0
HFD3_k127_5758930_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K13888 - - 0.00000008391 59.0
HFD3_k127_5758930_3 - - - - 0.00001458 51.0
HFD3_k127_5758930_4 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - 0.00002156 51.0
HFD3_k127_5768085_0 glutamate decarboxylase activity K01593 - 4.1.1.105,4.1.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 588.0
HFD3_k127_5768085_1 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009712 572.0
HFD3_k127_5768085_2 PFAM Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 490.0
HFD3_k127_5768085_3 Domain of unknown function (DUF4932) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008637 298.0
HFD3_k127_5768085_4 Stress responsive A/B Barrel Domain - - - 0.00000000000002464 77.0
HFD3_k127_5768085_5 Peptidase family M1 domain - - - 0.0000003145 58.0
HFD3_k127_5768085_6 SurA N-terminal domain K03770 - 5.2.1.8 0.000007988 57.0
HFD3_k127_5774415_0 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 331.0
HFD3_k127_5774415_1 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001814 295.0
HFD3_k127_5774415_2 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000002092 90.0
HFD3_k127_5774415_3 DnaJ molecular chaperone homology domain K19374 - - 0.00000000000001937 83.0
HFD3_k127_5774415_4 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.0000000000009053 74.0
HFD3_k127_5774415_5 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.0001485 45.0
HFD3_k127_5785576_0 Sulfatase maturase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005596 522.0
HFD3_k127_5785576_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006919 425.0
HFD3_k127_5785576_2 Histidine-specific methyltransferase, SAM-dependent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 331.0
HFD3_k127_5785576_3 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.00000000000000000000000000004852 119.0
HFD3_k127_5785576_4 Ntpase (Nacht family) - - - 0.0000000001052 72.0
HFD3_k127_5793776_0 PFAM Alanine dehydrogenase PNT, C-terminal domain K00324 - 1.6.1.2 7.757e-200 634.0
HFD3_k127_5793776_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006887 582.0
HFD3_k127_5793776_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 560.0
HFD3_k127_5793776_3 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000004768 177.0
HFD3_k127_5793776_4 Ferredoxin - - - 0.0000000000000000000001597 105.0
HFD3_k127_5798367_0 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000005529 275.0
HFD3_k127_5798367_1 Actin K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006714 258.0
HFD3_k127_5807455_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1325.0
HFD3_k127_5807455_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 479.0
HFD3_k127_5807455_2 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003741 279.0
HFD3_k127_5807455_3 - - - - 0.0000004986 51.0
HFD3_k127_581653_0 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806,K12503,K14215,K21273 GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008834,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0050347,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.68,2.5.1.86,2.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001837 282.0
HFD3_k127_581653_1 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003083 263.0
HFD3_k127_581653_10 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000004035 133.0
HFD3_k127_581653_11 Belongs to the R-transferase family K21420 - 2.3.2.29 0.0000000000000000000000000008384 115.0
HFD3_k127_581653_12 CarD-like/TRCF domain K07736 - - 0.000000000000000000000000003082 118.0
HFD3_k127_581653_13 Protein of unknown function (DUF952) - - - 0.00000000000000000005439 93.0
HFD3_k127_581653_2 orotate phosphoribosyltransferase activity K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000008776 215.0
HFD3_k127_581653_3 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000002247 214.0
HFD3_k127_581653_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000001095 193.0
HFD3_k127_581653_5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02342,K03763 - 2.7.7.7 0.000000000000000000000000000000000000000000000001284 184.0
HFD3_k127_581653_6 phosphohistidine phosphatase, SixA K08296 - - 0.00000000000000000000000000000000000000325 151.0
HFD3_k127_581653_7 TonB-dependent receptor K02014 - - 0.00000000000000000000000000000000000000383 162.0
HFD3_k127_581653_8 ASCH - - - 0.0000000000000000000000000000000000000641 147.0
HFD3_k127_581653_9 - - - - 0.00000000000000000000000000000000005883 142.0
HFD3_k127_5821939_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009334 422.0
HFD3_k127_5821939_1 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000008455 236.0
HFD3_k127_5821939_2 ABC-type sugar transport system periplasmic component K10439 - - 0.000000000000000000000000000000000000000000000000000000000000005713 229.0
HFD3_k127_5821939_3 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.0000000000000000000000000000000000000000000000000001579 195.0
HFD3_k127_5827822_0 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002196 290.0
HFD3_k127_5827822_1 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000000000000001648 214.0
HFD3_k127_5827822_2 ECF sigma factor - - - 0.000000000000000000000000000000248 127.0
HFD3_k127_5830277_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.566e-209 681.0
HFD3_k127_5830277_1 UDP binding domain K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007323 560.0
HFD3_k127_5830277_2 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 479.0
HFD3_k127_5830277_3 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 357.0
HFD3_k127_5830277_4 NAD(P)H-binding K01784,K02473 - 5.1.3.2,5.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 342.0
HFD3_k127_5830277_5 Periplasmic binding protein domain K02058,K10543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004855 326.0
HFD3_k127_5830277_6 PFAM ROK family protein K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000001444 235.0
HFD3_k127_5830277_7 DHH family K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000001449 125.0
HFD3_k127_5830277_8 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000000005343 123.0
HFD3_k127_5830277_9 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000002146 97.0
HFD3_k127_5832391_0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 382.0
HFD3_k127_5832391_1 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 393.0
HFD3_k127_5832391_2 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000002738 267.0
HFD3_k127_5832391_3 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000002203 216.0
HFD3_k127_5832391_4 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000000000000001881 146.0
HFD3_k127_5869849_0 PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 2.169e-207 664.0
HFD3_k127_5869849_1 Phosphate acyltransferases K00655,K01897 - 2.3.1.51,6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006503 605.0
HFD3_k127_5869849_2 Citrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 466.0
HFD3_k127_5869849_3 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.0000000000000000000000000000000000000000001806 166.0
HFD3_k127_58718_0 TIGRFAM UTP--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 361.0
HFD3_k127_58718_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000003942 190.0
HFD3_k127_58718_2 Multicopper oxidase - - - 0.0000000000000000000000001401 111.0
HFD3_k127_58813_0 Peptidase family M1 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004446 539.0
HFD3_k127_58813_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000001302 191.0
HFD3_k127_58813_2 TPR repeat - - - 0.00000000000000000004142 93.0
HFD3_k127_58813_3 MerR HTH family regulatory protein - - - 0.00000000001103 73.0
HFD3_k127_5883303_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 446.0
HFD3_k127_5883303_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007811 255.0
HFD3_k127_5883303_2 cobalamin-transporting ATPase activity K02014,K16092 - - 0.00000000000000000000000000000000000000000000000000000000000000002861 235.0
HFD3_k127_5883303_3 Histidine kinase - - - 0.000000000000000000002323 109.0
HFD3_k127_5903010_0 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.00000000000000000000000000000000000000000000000000000000005422 208.0
HFD3_k127_5903010_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000001126 80.0
HFD3_k127_592312_0 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177,K03483 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000003559 236.0
HFD3_k127_592312_1 double-stranded DNA 3'-5' exodeoxyribonuclease activity K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000001008 230.0
HFD3_k127_592312_3 Modulates RecA activity K03565,K19002 GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0019899,GO:0031668,GO:0033554,GO:0043086,GO:0044092,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496 2.4.1.337 0.00000000000003143 81.0
HFD3_k127_5946933_0 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 399.0
HFD3_k127_5946933_1 PAS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 300.0
HFD3_k127_5946933_2 Exodeoxyribonuclease iii K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000001661 229.0
HFD3_k127_5946933_3 - - - - 0.0000000000000000000000000000000000000000000001569 172.0
HFD3_k127_5966870_0 PFAM Organic solvent tolerance protein K04744 - - 0.000000000000000000000000000000000000000000000000005018 203.0
HFD3_k127_5969045_0 Aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 369.0
HFD3_k127_5969045_1 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000001035 114.0
HFD3_k127_5969045_2 Peptidase M61 - - - 0.000000000008495 73.0
HFD3_k127_597216_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 2.542e-229 719.0
HFD3_k127_597216_1 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 501.0
HFD3_k127_597216_2 PFAM short chain dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005665 428.0
HFD3_k127_597216_3 PFAM PhoH family protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 357.0
HFD3_k127_597216_4 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001216 288.0
HFD3_k127_597216_5 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000003039 109.0
HFD3_k127_597216_6 Glucose-6-phosphate dehydrogenase, NAD binding domain K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000006407 107.0
HFD3_k127_597216_7 COG3668 Plasmid stabilization system protein - - - 0.0000000000000000002814 88.0
HFD3_k127_5972477_0 Glycogen debranching enzyme - - - 1.93e-216 689.0
HFD3_k127_5972477_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 296.0
HFD3_k127_5972477_2 Zinc carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005956 289.0
HFD3_k127_5972477_3 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000254 207.0
HFD3_k127_5972477_4 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000007797 191.0
HFD3_k127_5996518_0 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 514.0
HFD3_k127_5996518_1 Putative modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 499.0
HFD3_k127_6002344_0 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005747 267.0
HFD3_k127_6002344_1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000003303 171.0
HFD3_k127_6002344_2 Thioredoxin-like - - - 0.00000000000000000000000000000000000113 147.0
HFD3_k127_6002344_3 belongs to the Fur family K03711,K09825 - - 0.000000000000000000000000000002722 124.0
HFD3_k127_6002344_4 Domain of unknown function (DUF4112) - - - 0.0000000000000000000000000009526 118.0
HFD3_k127_6010181_0 Carbon starvation protein K06200 - - 3.878e-200 640.0
HFD3_k127_6010181_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006497 542.0
HFD3_k127_6010181_2 nitric oxide reductase activity K03809 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005699 306.0
HFD3_k127_6010181_3 PFAM thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000001053 228.0
HFD3_k127_6010181_4 Domain of unknown function (DUF4870) - - - 0.00006775 53.0
HFD3_k127_6013474_0 Trypsin-like peptidase domain - - - 0.00000000000000000000000000000000000000000000000000000006977 211.0
HFD3_k127_6013474_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K04750 - - 0.00000000000000000000000000000000000000000000000000002443 192.0
HFD3_k127_6013474_2 ribose 5-phosphate isomerase B K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000004941 173.0
HFD3_k127_6013474_3 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.000000000000000000000000000000000002426 138.0
HFD3_k127_6028707_0 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005146 418.0
HFD3_k127_6028707_1 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000000000000001241 220.0
HFD3_k127_6028707_2 peptidase activity - - - 0.000000000000000000000000006367 114.0
HFD3_k127_6028707_3 cAMP biosynthetic process - - - 0.00000000000000000000006282 114.0
HFD3_k127_6031369_0 COG3653 N-acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 2.261e-213 675.0
HFD3_k127_6031369_1 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 550.0
HFD3_k127_6033100_0 Prolyl oligopeptidase, N-terminal beta-propeller domain - - - 6.164e-201 648.0
HFD3_k127_6033100_1 TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005737 431.0
HFD3_k127_6033100_2 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.0000000000000000000000001704 106.0
HFD3_k127_6033643_0 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000005218 155.0
HFD3_k127_603532_0 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 426.0
HFD3_k127_603532_1 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 411.0
HFD3_k127_603532_2 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 309.0
HFD3_k127_603532_3 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005733 290.0
HFD3_k127_603532_4 Belongs to the DapB family K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000005039 195.0
HFD3_k127_603532_5 Domain of unknown function (DUF4440) - - - 0.000000000000000000000000000000000000000003018 161.0
HFD3_k127_603532_6 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000000001919 148.0
HFD3_k127_603532_7 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0000000000000000000000000000000001716 138.0
HFD3_k127_603532_8 - - - - 0.000000000000002759 83.0
HFD3_k127_6040322_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 599.0
HFD3_k127_6040322_1 Pfam RibD C-terminal domain K00287 - 1.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000188 252.0
HFD3_k127_6046299_0 Aldehyde dehydrogenase family K00128,K00138 - 1.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009756 481.0
HFD3_k127_6046299_1 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004665 407.0
HFD3_k127_6046299_2 ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000001036 237.0
HFD3_k127_6046299_3 PFAM peptidase M50 - - - 0.00000000000000000000000000000000000000002793 160.0
HFD3_k127_6063940_0 PFAM Class II aldolase adducin K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000005304 221.0
HFD3_k127_6063940_1 four-way junction helicase activity K03550 GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.000000000000000000000000000000000000000000000000001388 188.0
HFD3_k127_6070753_0 Protein of unknown function (DUF4256) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 306.0
HFD3_k127_6070753_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000327 280.0
HFD3_k127_6070753_2 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002505 234.0
HFD3_k127_6070753_3 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000000004732 208.0
HFD3_k127_6070753_4 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.00000000000000000000000000000000000000000000000008593 180.0
HFD3_k127_6077119_0 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002529 278.0
HFD3_k127_6077119_1 DNA recombination-mediator protein A K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007314 256.0
HFD3_k127_6077119_2 lipid A biosynthetic process K02536 - 2.3.1.191 0.0000000000000000000000000000000000000003549 151.0
HFD3_k127_6077648_0 Belongs to the glycosyl hydrolase 32 family K00692 - 2.4.1.10 0.000000000000000000000000000000000000000000000000000000000000008866 234.0
HFD3_k127_6077648_1 C4-type zinc ribbon domain K07164 - - 0.0000000000000000000006752 105.0
HFD3_k127_6077648_2 peptidyl-tyrosine sulfation - - - 0.0000002352 63.0
HFD3_k127_6080908_0 phosphoglycerate mutase activity K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000039 375.0
HFD3_k127_6080908_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 342.0
HFD3_k127_6080908_2 Mur ligase, middle domain K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000005195 278.0
HFD3_k127_6080908_3 Inositol monophosphatase K01082,K01092 GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000001844 265.0
HFD3_k127_6080908_4 Protein of unknown function (DUF4197) - - - 0.00000000000000000000000000000000000000000000000000008765 196.0
HFD3_k127_6080908_5 Protein of unknown function (DUF1572) - - - 0.000000000000000000000000000000000000000000000009874 180.0
HFD3_k127_6080908_6 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.00000000000006151 72.0
HFD3_k127_6089018_0 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004593 273.0
HFD3_k127_6089018_1 Tetratricopeptide repeats - - - 0.00000000000000000000000000007977 131.0
HFD3_k127_6100447_0 peptidase M24B X-Pro dipeptidase aminopeptidase domain protein K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002967 379.0
HFD3_k127_6100447_1 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.0000000000001414 73.0
HFD3_k127_6109399_0 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 509.0
HFD3_k127_6109399_1 Belongs to the glycosyl hydrolase 32 family K00692 - 2.4.1.10 0.00000000000000000000000000000000000000000000000001146 198.0
HFD3_k127_6109399_2 CHRD domain - - - 0.000000000000937 81.0
HFD3_k127_6113597_0 PFAM secretion protein HlyD family protein K01993,K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000571 401.0
HFD3_k127_6113597_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001634 277.0
HFD3_k127_6113597_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000008144 194.0
HFD3_k127_6113597_3 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000104 166.0
HFD3_k127_6113597_4 AraC-like ligand binding domain - - - 0.00000000000000000009281 95.0
HFD3_k127_6113597_5 DinB family - - - 0.000004263 55.0
HFD3_k127_6143053_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 4.779e-208 660.0
HFD3_k127_6143053_1 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000008612 251.0
HFD3_k127_6143053_2 metal-dependent membrane protease K07052 - - 0.000000001354 68.0
HFD3_k127_6156175_0 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 426.0
HFD3_k127_6156175_1 Amino acid kinase family K00928,K12524 - 1.1.1.3,2.7.2.4 0.0000000000000000002269 95.0
HFD3_k127_6156175_2 - - - - 0.000000000000001616 78.0
HFD3_k127_6156175_3 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000001244 62.0
HFD3_k127_619683_0 Domain of unknown function (DUF5009) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003616 359.0
HFD3_k127_619683_2 Belongs to the metal hydrolase YfiT family - - - 0.0000000000000000000000000000000000000005002 150.0
HFD3_k127_6202191_0 Penicillin amidase K01434 - 3.5.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000743 460.0
HFD3_k127_6202191_1 Peptidase family M23 K21472 - - 0.000000000000000000000000000000000000000003671 163.0
HFD3_k127_6202191_2 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000002046 87.0
HFD3_k127_6202191_3 peptidase M15B and M15C DD-carboxypeptidase VanY - - - 0.00000000000006125 81.0
HFD3_k127_6202191_4 Cytochrome c K00406 - - 0.00003679 52.0
HFD3_k127_6234402_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 362.0
HFD3_k127_6234402_1 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000005482 201.0
HFD3_k127_6234402_2 Domain of unknown function (DUF5122) beta-propeller - - - 0.0000000000000000000000000000000000000000000004444 180.0
HFD3_k127_6234402_3 Glycine cleavage T-protein C-terminal barrel domain K00605,K06980 - 2.1.2.10 0.00000000000000000000000000000000003469 146.0
HFD3_k127_6234402_4 deaminated base DNA N-glycosylase activity K21929 - 3.2.2.27 0.00000000000000000000000000000002037 139.0
HFD3_k127_6238474_0 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006842 399.0
HFD3_k127_6238474_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 288.0
HFD3_k127_6238474_2 with different specificities (related to short-chain alcohol K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000447 222.0
HFD3_k127_6259251_0 Cytochrome C biogenesis protein transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006569 465.0
HFD3_k127_6259251_1 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008161 399.0
HFD3_k127_6259251_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 377.0
HFD3_k127_6259251_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 371.0
HFD3_k127_6259251_4 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002665 286.0
HFD3_k127_6259251_5 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000001121 269.0
HFD3_k127_6259251_6 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000001092 153.0
HFD3_k127_6259251_7 Cysteine dioxygenase type I K00456 - 1.13.11.20 0.000000000000000000000000000000001193 136.0
HFD3_k127_6259251_8 EamA-like transporter family - - - 0.0000000000000000000000000000002537 136.0
HFD3_k127_6263017_0 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002904 280.0
HFD3_k127_6263017_1 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000000007145 196.0
HFD3_k127_6263017_2 Bacterial Ig-like domain (group 1) - - - 0.0000000000000000000000000000000006452 151.0
HFD3_k127_6272617_0 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 562.0
HFD3_k127_6272617_1 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 316.0
HFD3_k127_6272617_2 - - - - 0.00000005311 56.0
HFD3_k127_627522_0 ABC-2 family transporter protein K19341 - - 0.000000000000000000000000000000000005277 145.0
HFD3_k127_627522_1 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000002219 141.0
HFD3_k127_627522_2 Outer membrane efflux protein - - - 0.000000000000000000000000000001715 133.0
HFD3_k127_627522_3 Protein of unknown function (DUF2892) - - - 0.000000000000000009085 84.0
HFD3_k127_6277244_0 Glutamine amidotransferases class-II K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005831 560.0
HFD3_k127_6277244_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 310.0
HFD3_k127_6277244_2 Pyridoxamine 5'-phosphate oxidase like - - - 0.00000000000000000000000000000000000000000000000000000002833 201.0
HFD3_k127_6277244_3 - - - - 0.0000003196 57.0
HFD3_k127_6283212_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 282.0
HFD3_k127_6283212_1 histidine kinase-, DNA gyrase B - - - 0.00000000000000000000000000000000000000000001564 185.0
HFD3_k127_6283212_2 - - - - 0.000000000000000000000000000000000000006697 148.0
HFD3_k127_6290838_0 Serves to protect cells from the toxic effects of hydrogen peroxide K03781 - 1.11.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006463 379.0
HFD3_k127_6290838_1 Serves to protect cells from the toxic effects of hydrogen peroxide K03781 - 1.11.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 293.0
HFD3_k127_6318197_0 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 381.0
HFD3_k127_6318197_1 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000003102 248.0
HFD3_k127_6318197_2 rod shape-determining protein MreD K03571 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - 0.0000003422 58.0
HFD3_k127_6331106_0 sequence-specific DNA binding K01697,K01738 GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0016020,GO:0019842,GO:0030170,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071944,GO:0097159,GO:1901363 2.5.1.47,4.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007707 524.0
HFD3_k127_6331106_1 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 448.0
HFD3_k127_6331106_2 cell redox homeostasis K22278 - 3.5.1.104 0.00000000000000000001092 106.0
HFD3_k127_6331106_3 - - - - 0.00000000000000000004675 100.0
HFD3_k127_6331106_4 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000002051 81.0
HFD3_k127_6331106_5 SMART Elongator protein 3 MiaB NifB - - - 0.00000000001074 64.0
HFD3_k127_6331106_6 Forkhead associated domain - - - 0.00000000002629 74.0
HFD3_k127_6331106_7 CHAP domain - - - 0.00000001255 63.0
HFD3_k127_6336303_0 Natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003119 415.0
HFD3_k127_6336303_1 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000887 334.0
HFD3_k127_6336303_2 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000007612 262.0
HFD3_k127_6336303_3 PFAM Phosphate acetyl butaryl transferase K00625 GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.8 0.000000000000000000000000000000000007394 138.0
HFD3_k127_6336303_4 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000003835 136.0
HFD3_k127_6338367_0 HAD superfamily, subfamily IIIB (Acid phosphatase) - - - 0.00000000000000000000000000000000000000000000000000000000000000116 233.0
HFD3_k127_6338367_1 Glyoxalase K04750 - - 0.000000000000000000000000000000000000000000000004523 176.0
HFD3_k127_6338367_2 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000002641 173.0
HFD3_k127_6338367_3 serine-type peptidase activity K01278 - 3.4.14.5 0.0000000000006781 78.0
HFD3_k127_6357727_0 Beta-eliminating lyase K01667 - 4.1.99.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008352 566.0
HFD3_k127_6357727_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 550.0
HFD3_k127_6357727_10 FtsZ-dependent cytokinesis - - - 0.00000000000000006195 90.0
HFD3_k127_6357727_11 Domain of unknown function (DUF4870) - - - 0.0000000001808 66.0
HFD3_k127_6357727_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004734 325.0
HFD3_k127_6357727_3 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002674 284.0
HFD3_k127_6357727_4 GHMP kinases C terminal K07031 - 2.7.1.168 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000125 280.0
HFD3_k127_6357727_5 Cytochrome c7 and related cytochrome c K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.000000000000000000000000000000000000000000000000000000000000000000000000002253 259.0
HFD3_k127_6357727_6 Pfam:UPF0118 - - - 0.00000000000000000000000000000000000000000000000000000000000003904 224.0
HFD3_k127_6357727_7 - - - - 0.0000000000000000000000000000000000000000000007299 177.0
HFD3_k127_6357727_8 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000001152 130.0
HFD3_k127_6357727_9 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000001251 96.0
HFD3_k127_6392905_0 von Willebrand factor, type A - - - 0.00000000000000000000000000000000000000000055 173.0
HFD3_k127_6405860_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009892 474.0
HFD3_k127_6405860_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 393.0
HFD3_k127_6405860_2 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000002477 220.0
HFD3_k127_6405860_3 AcrB/AcrD/AcrF family K03296 - - 0.00000000000000000000000000000000000000000004062 181.0
HFD3_k127_6405860_4 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000831 153.0
HFD3_k127_6405860_5 PFAM von Willebrand factor type A - - - 0.0000000000000000000000000000000003533 143.0
HFD3_k127_6405860_6 Arginase family K01476 - 3.5.3.1 0.00000000000000000000000000005071 118.0
HFD3_k127_6405860_7 Transcriptional regulatory protein, C terminal K07669,K07672 - - 0.00000000000000000000282 98.0
HFD3_k127_6406061_0 PFAM UDP-galactopyranose mutase, C-terminal K01854 - 5.4.99.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004445 589.0
HFD3_k127_6406061_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 453.0
HFD3_k127_6406061_2 COGs COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase - - - 0.00000000000000000000000000000000000000000000001512 181.0
HFD3_k127_6406061_3 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000000000008743 170.0
HFD3_k127_6406689_0 MobA-like NTP transferase domain K07141,K19190 - 1.1.1.328,2.7.7.76 0.0000000000000000000000000000000008505 135.0
HFD3_k127_6408210_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007313 614.0
HFD3_k127_6410498_0 Belongs to the BI1 family K06890 - - 0.000000000000000000000000000000000000000000000000000000000000000001634 234.0
HFD3_k127_6410498_1 DoxX - - - 0.0000000000000000000000000000000000000383 147.0
HFD3_k127_6410498_2 peroxiredoxin activity K03564 - 1.11.1.15 0.0000000000000000000006712 98.0
HFD3_k127_6410498_3 - - - - 0.00000000000000000001541 93.0
HFD3_k127_6410498_5 Exonuclease VII small subunit K03602 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 0.00000000000005045 77.0
HFD3_k127_6410498_6 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000008665 66.0
HFD3_k127_6412922_0 Non-ribosomal peptide synthetase modules and related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 291.0
HFD3_k127_6412922_1 Thioesterase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004486 250.0
HFD3_k127_6416213_0 POT family K03305 - - 2.432e-223 702.0
HFD3_k127_6416213_1 Insulinase (Peptidase family M16) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004977 353.0
HFD3_k127_6416213_2 - - - - 0.000000000000000000000000000000000000000000000000000000000007069 219.0
HFD3_k127_6416213_3 Insulinase (Peptidase family M16) - - - 0.00000000000005036 78.0
HFD3_k127_6421736_0 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000002638 262.0
HFD3_k127_6421736_1 GlcNAc-PI de-N-acetylase K01463 - - 0.000000000000000000000000000000000000000000000000113 186.0
HFD3_k127_6421736_2 DinB superfamily - - - 0.000000000000000000000000000000000000000000001183 170.0
HFD3_k127_6421736_3 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000002246 145.0
HFD3_k127_6421736_4 DnaJ molecular chaperone homology domain - - - 0.0000000000000000000000000000005457 132.0
HFD3_k127_6421736_5 beta-lactamase domain protein - - - 0.0000000000000000000000000002593 124.0
HFD3_k127_6421736_6 - - - - 0.0000000000000000002679 100.0
HFD3_k127_6421736_7 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000004458 62.0
HFD3_k127_6421736_8 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000963 57.0
HFD3_k127_6427862_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.609e-232 728.0
HFD3_k127_6427862_1 PFAM Sodium sulphate symporter K14445 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 483.0
HFD3_k127_6427862_10 VanZ like family - - - 0.00000000000000000001287 98.0
HFD3_k127_6427862_11 Trm112p-like protein K09791 - - 0.00000000000000000004696 90.0
HFD3_k127_6427862_12 Putative addiction module component - - - 0.0000000000000000007456 90.0
HFD3_k127_6427862_13 Glycosyltransferase family 9 (heptosyltransferase) K02849 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0071704,GO:0071967,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.0000000000000000009491 95.0
HFD3_k127_6427862_14 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000003297 74.0
HFD3_k127_6427862_15 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0001043 51.0
HFD3_k127_6427862_2 virion core protein, lumpy skin disease virus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006375 419.0
HFD3_k127_6427862_3 DNA methylase K00571,K07319 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006437 392.0
HFD3_k127_6427862_4 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000545 302.0
HFD3_k127_6427862_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001256 277.0
HFD3_k127_6427862_6 lactoylglutathione lyase activity K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000004687 160.0
HFD3_k127_6427862_7 PFAM Plasmid stabilisation system - - - 0.000000000000000000000000000000000000005848 148.0
HFD3_k127_6427862_8 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000119 123.0
HFD3_k127_6427862_9 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.0000000000000000000002755 99.0
HFD3_k127_64287_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 317.0
HFD3_k127_6441299_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 3.736e-245 774.0
HFD3_k127_6441299_1 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 437.0
HFD3_k127_6441299_2 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000000004373 250.0
HFD3_k127_6441299_3 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000006889 153.0
HFD3_k127_6441299_4 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.00000000000000000000000000000000001108 141.0
HFD3_k127_6441299_5 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000005088 119.0
HFD3_k127_6441299_6 Lipopolysaccharide-assembly - - - 0.000000000000000003482 93.0
HFD3_k127_6441299_7 zinc-ribbon domain - - - 0.0000003719 60.0
HFD3_k127_6445052_0 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002899 307.0
HFD3_k127_6445052_2 Dehydrogenase E1 component K11381 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 287.0
HFD3_k127_6445052_3 Acetyltransferase (GNAT) domain K03829 - - 0.000000000000000000000000000000000000000000000000000000000000009881 218.0
HFD3_k127_6445052_4 OsmC-like protein K07397 - - 0.000000000000000000000000000000000000001507 151.0
HFD3_k127_6445052_7 Periplasmic or secreted lipoprotein - - - 0.0008954 52.0
HFD3_k127_6446391_0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 432.0
HFD3_k127_6446391_1 Belongs to the UPF0502 family K09915 - - 0.000000000000000000000000000000000000000000000000000000000000003033 223.0
HFD3_k127_6446391_2 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000001648 177.0
HFD3_k127_6446391_3 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000313 147.0
HFD3_k127_6446391_4 Peptidase M56 - - - 0.000000000000000000000001751 114.0
HFD3_k127_6446391_5 Tetratricopeptide repeat - - - 0.0002131 53.0
HFD3_k127_6447753_0 endonuclease III - - - 0.00000000000000000000000000000000000000000000000000000002104 203.0
HFD3_k127_6447753_1 Protein of unknown function, DUF488 - - - 0.000000000000003831 81.0
HFD3_k127_6447753_2 PFAM CHAD domain containing protein - - - 0.0000000000216 74.0
HFD3_k127_6447753_3 methyltransferase - - - 0.000001357 52.0
HFD3_k127_6456049_0 PFAM Peptidase family M3 K01284 - 3.4.15.5 5.331e-267 828.0
HFD3_k127_6456049_1 Two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 515.0
HFD3_k127_6456049_2 signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003471 340.0
HFD3_k127_6478497_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 4.525e-274 862.0
HFD3_k127_6478497_1 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004075 412.0
HFD3_k127_6478497_2 Voltage-dependent anion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007072 403.0
HFD3_k127_6478497_3 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.00000000000000000000000000005513 118.0
HFD3_k127_6478497_5 Protein of unknown function (DUF3565) - - - 0.000000000000000000001156 96.0
HFD3_k127_6478497_6 nitrite reductase [NAD(P)H] activity K08355 - 1.20.2.1,1.20.9.1 0.00000000000000000007383 90.0
HFD3_k127_6489382_0 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 2.241e-266 839.0
HFD3_k127_6489382_1 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 334.0
HFD3_k127_6489382_2 Protein of unknown function (DUF1203) - - - 0.0000000000000000000000000003161 119.0
HFD3_k127_6498280_0 Domain of unknown function (DUF5122) beta-propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006408 282.0
HFD3_k127_6498280_1 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000002132 91.0
HFD3_k127_6498280_2 Sulfite exporter TauE/SafE - - - 0.0003277 47.0
HFD3_k127_6504563_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 4.753e-320 992.0
HFD3_k127_6504563_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 5.687e-235 741.0
HFD3_k127_6504563_2 Osmosensitive K channel His kinase sensor K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004103 411.0
HFD3_k127_6504563_3 response regulator, receiver K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 291.0
HFD3_k127_6504563_4 Histidine kinase K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001131 292.0
HFD3_k127_6504563_5 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000003465 215.0
HFD3_k127_6504563_7 Cupin domain - - - 0.0000000000004321 79.0
HFD3_k127_6504563_8 - - - - 0.0000000003111 64.0
HFD3_k127_6523517_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004007 317.0
HFD3_k127_6523517_1 Disulphide isomerase - - - 0.000000000000000000000000000000000000000002073 159.0
HFD3_k127_6523517_2 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000005749 150.0
HFD3_k127_6523517_3 Hydrolase, P-loop family K06925 - - 0.0000000000000000000001998 104.0
HFD3_k127_6523517_4 Tetratricopeptide repeat - - - 0.00000000000000005374 87.0
HFD3_k127_6523517_5 Belongs to the HpcH HpaI aldolase family - - - 0.000000000000003438 78.0
HFD3_k127_6523517_6 PFAM Adenylate cyclase K05873 - 4.6.1.1 0.0000000000000528 80.0
HFD3_k127_6525612_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1217.0
HFD3_k127_6525612_1 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000001456 227.0
HFD3_k127_6525612_2 Methyltransferase domain - - - 0.00000000000000000000039 104.0
HFD3_k127_6525612_3 Putative zinc- or iron-chelating domain K06940 - - 0.00000000002047 74.0
HFD3_k127_6525612_4 TIGRFAM DNA protecting protein DprA K04096 - - 0.00001868 49.0
HFD3_k127_658409_0 Transposase IS200 like - - - 0.0000005859 51.0
HFD3_k127_658409_1 Belongs to the glycosyl hydrolase 32 family K00692 - 2.4.1.10 0.0003987 44.0
HFD3_k127_658409_2 SPFH domain-Band 7 family - - - 0.0009726 42.0
HFD3_k127_6601808_0 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 393.0
HFD3_k127_6601808_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 329.0
HFD3_k127_6601808_10 Recombinase - - - 0.000686 44.0
HFD3_k127_6601808_2 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 310.0
HFD3_k127_6601808_3 Belongs to the glycosyl hydrolase 32 family K00692 - 2.4.1.10 0.000000000000000000000000000000000000000000000000000000000000000001482 239.0
HFD3_k127_6601808_4 Phosphomethylpyrimidine kinase K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000001748 240.0
HFD3_k127_6601808_5 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000001374 221.0
HFD3_k127_6601808_6 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000001316 175.0
HFD3_k127_6601808_7 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.00000000000000000000000000000000000002299 145.0
HFD3_k127_6601808_8 YjbR - - - 0.000000000000000000000000000000001246 133.0
HFD3_k127_6632337_0 ligase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 381.0
HFD3_k127_6635981_0 Belongs to the aldehyde dehydrogenase family K00128,K00130,K10217 - 1.2.1.3,1.2.1.32,1.2.1.8,1.2.1.85 5.738e-212 668.0
HFD3_k127_6635981_1 Peptidase family S58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 479.0
HFD3_k127_6635981_2 mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008081 394.0
HFD3_k127_6635981_3 Cleaves the N-terminal amino acid of tripeptides K01258 GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0034641,GO:0034701,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045148,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004089 389.0
HFD3_k127_6635981_4 Belongs to the dCTP deaminase family K01494 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009314,GO:0009394,GO:0009628,GO:0009987,GO:0015949,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.5.4.13 0.00000000000000000000000000000000000000000000004727 173.0
HFD3_k127_6635981_5 GrpB protein - - - 0.000000000000000000000000000000000001547 144.0
HFD3_k127_6637244_0 PFAM peptidase T2 asparaginase 2 K01444,K13051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.19.5,3.5.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003808 418.0
HFD3_k127_6637244_1 PFAM Glycosyl transferase family 2 K10012 - 2.4.2.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 364.0
HFD3_k127_6637244_2 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.0000000000000000000000000000000000000000003359 160.0
HFD3_k127_6637244_3 Methyltransferase domain - - - 0.000007971 50.0
HFD3_k127_6641372_0 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003016 291.0
HFD3_k127_6641372_1 acetyltransferase K06976 - - 0.000000000000000001032 97.0
HFD3_k127_6641372_2 GGDEF domain - - - 0.0001846 49.0
HFD3_k127_664169_0 aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 448.0
HFD3_k127_664169_1 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 430.0
HFD3_k127_664169_10 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.000000000000000000000000000000000000002712 149.0
HFD3_k127_664169_11 binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000000008841 147.0
HFD3_k127_664169_12 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000004051 138.0
HFD3_k127_664169_13 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000002401 127.0
HFD3_k127_664169_14 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000007789 98.0
HFD3_k127_664169_15 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000003261 97.0
HFD3_k127_664169_16 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000258 84.0
HFD3_k127_664169_17 sporulation resulting in formation of a cellular spore - - - 0.0000002113 64.0
HFD3_k127_664169_2 Participates in initiation and elongation during chromosome replication K02314 GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003903 404.0
HFD3_k127_664169_3 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 386.0
HFD3_k127_664169_4 Endonuclease/Exonuclease/phosphatase family K07004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001526 260.0
HFD3_k127_664169_5 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000000007652 220.0
HFD3_k127_664169_6 Belongs to the metal hydrolase YfiT family - - - 0.00000000000000000000000000000000000000000000000000000000003753 209.0
HFD3_k127_664169_7 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000005803 181.0
HFD3_k127_664169_8 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000669 178.0
HFD3_k127_664169_9 PFAM OsmC family protein K04063 - - 0.0000000000000000000000000000000000000000006064 162.0
HFD3_k127_6643499_0 Subtilase family K17734 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 328.0
HFD3_k127_6643499_1 response regulator, receiver - - - 0.000000000000000007942 88.0
HFD3_k127_6643499_2 protein conserved in bacteria (DUF2179) - - - 0.0000000000000001211 81.0
HFD3_k127_6682555_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 370.0
HFD3_k127_6682555_1 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008252 321.0
HFD3_k127_6682555_2 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005623,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002146 276.0
HFD3_k127_6682555_3 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000002985 186.0
HFD3_k127_6682555_4 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000001917 171.0
HFD3_k127_6682555_5 PFAM NUDIX hydrolase K01515 - 3.6.1.13 0.00000000000000000000000000000000000007592 148.0
HFD3_k127_6682555_6 Protein of unknown function (DUF1569) - - - 0.000000000000000000000000000000000002812 142.0
HFD3_k127_6682555_7 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000002902 127.0
HFD3_k127_6682555_8 - - - - 0.0000000000000000000000000006644 119.0
HFD3_k127_6720990_0 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004332 386.0
HFD3_k127_6720990_1 Belongs to the PstS family K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 359.0
HFD3_k127_6720990_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 350.0
HFD3_k127_6720990_3 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 312.0
HFD3_k127_6720990_4 Phosphate transport system permease K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005619 267.0
HFD3_k127_6720990_5 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000000001198 190.0
HFD3_k127_6720990_6 PhoU domain K02039 - - 0.00000000000000000000000000000000000000000006347 171.0
HFD3_k127_6735972_0 Phage late control gene D protein (GPD) K11904 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003344 498.0
HFD3_k127_6735972_1 C-terminal, D2-small domain, of ClpB protein K11907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001414 242.0
HFD3_k127_6738327_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001234 277.0
HFD3_k127_6738327_1 protein N-acetylglucosaminyltransferase activity - - - 0.00000000000000000000000000000000005212 150.0
HFD3_k127_6738327_2 PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000000000007998 93.0
HFD3_k127_6738327_3 - - - - 0.0002876 48.0
HFD3_k127_6771305_0 Alpha/beta hydrolase family - - - 3.028e-268 843.0
HFD3_k127_6771305_1 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.0002429 45.0
HFD3_k127_6777212_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 626.0
HFD3_k127_6777212_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 361.0
HFD3_k127_6777212_2 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 284.0
HFD3_k127_6777212_3 Domain of unknown function (DUF1990) - - - 0.00000000000000000000000000000000000000000000000004946 185.0
HFD3_k127_6777212_4 PFAM MgtC SapB transporter K07507 - - 0.00000000000000000000000000000000000000000006691 165.0
HFD3_k127_6777212_5 Tetratricopeptide repeat - - - 0.000000000000000000000000001746 129.0
HFD3_k127_6777212_6 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00004279 51.0
HFD3_k127_6777667_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 533.0
HFD3_k127_6777667_1 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000009872 250.0
HFD3_k127_6777667_2 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000001786 190.0
HFD3_k127_6777667_3 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000002969 146.0
HFD3_k127_6777667_4 Ribosomal protein L35 K02916 - - 0.000000000000000001621 87.0
HFD3_k127_6780176_0 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003883 550.0
HFD3_k127_6780176_1 Transcriptional regulatory protein, C terminal - - - 0.000000000006677 68.0
HFD3_k127_6781167_0 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 349.0
HFD3_k127_6781167_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000002126 241.0
HFD3_k127_6781167_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006780,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046394,GO:0046483,GO:0046501,GO:0046502,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 4.1.1.37 0.0000000000000000000000000000000000000000000001898 168.0
HFD3_k127_6781167_3 Uroporphyrinogen-III synthase K01719 - 4.2.1.75 0.00007871 53.0
HFD3_k127_6825004_0 Protein of unknown function (DUF3455) - - - 0.0000000000000000000007993 103.0
HFD3_k127_6889641_0 Bacterial transcriptional activator domain K03556 - - 0.0000000000000000000000000000000000000000000003516 180.0
HFD3_k127_6889641_1 trisaccharide binding K03556 - - 0.0000000000006545 78.0
HFD3_k127_6889641_2 - - - - 0.0000001022 59.0
HFD3_k127_6900665_0 Vault protein inter-alpha-trypsin domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 468.0
HFD3_k127_6900665_1 transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 422.0
HFD3_k127_6900665_2 protein related to plant photosystem II stability assembly factor - - - 0.00000000000000000000000000000000000004014 156.0
HFD3_k127_6922255_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 387.0
HFD3_k127_6922255_1 Acetyltransferase (GNAT) domain K03817 - - 0.000000000000000000000000000000000000000002145 163.0
HFD3_k127_6922255_2 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000000001656 132.0
HFD3_k127_6922255_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000001084 79.0
HFD3_k127_6927288_0 extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006013 273.0
HFD3_k127_6927288_1 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000007793 216.0
HFD3_k127_693240_0 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000006758 220.0
HFD3_k127_693240_1 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000001349 192.0
HFD3_k127_693240_2 YGGT family K02221 - - 0.0000000642 61.0
HFD3_k127_69408_0 Peptidase M16 inactive domain K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001436 290.0
HFD3_k127_69408_1 PFAM sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004493 291.0
HFD3_k127_69408_2 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006225 281.0
HFD3_k127_69408_3 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000001454 226.0
HFD3_k127_69408_4 cell septum assembly - - - 0.00000000000000000000000000000000000000000000000000009103 209.0
HFD3_k127_69408_5 Scaffold protein Nfu/NifU N terminal - - - 0.000000000000000000000000000000000000000000000000001502 188.0
HFD3_k127_69408_6 nuclear chromosome segregation - - - 0.00000000002665 76.0
HFD3_k127_69408_7 SnoaL-like domain - - - 0.00000008695 61.0
HFD3_k127_6942883_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2.037e-293 921.0
HFD3_k127_6942883_1 DNA-templated transcription, termination K02887,K03628 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 6.835e-207 653.0
HFD3_k127_6942883_2 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.00000000000000000000000000000000000000000000000000000007557 201.0
HFD3_k127_6942883_3 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000000000000876 142.0
HFD3_k127_6942883_4 - - - - 0.0000000000000000000000000000001048 127.0
HFD3_k127_6942883_5 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.0000184 48.0
HFD3_k127_6950684_0 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 465.0
HFD3_k127_6950684_1 assembly protein PilO K02664 - - 0.00006775 53.0
HFD3_k127_6958308_0 Involved in the tonB-independent uptake of proteins K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003491 518.0
HFD3_k127_6958308_1 phosphoesterase, PA-phosphatase related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000441 453.0
HFD3_k127_6958308_2 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000003374 236.0
HFD3_k127_6958308_3 OmpA family - - - 0.0000000000000000000000000000002056 135.0
HFD3_k127_6958308_4 dextransucrase activity - - - 0.0000000000000000004198 89.0
HFD3_k127_6958308_5 von Willebrand factor, type A K07114 - - 0.0000000000000001109 93.0
HFD3_k127_6958308_6 AAA ATPase domain - - - 0.00000000000009919 85.0
HFD3_k127_6958308_7 Lactonase, 7-bladed beta-propeller - - - 0.00000000000113 76.0
HFD3_k127_6958308_8 Catalyzes the synthesis of activated sulfate K00958 - 2.7.7.4 0.000000000003539 69.0
HFD3_k127_6958308_9 cAMP biosynthetic process - - - 0.0000004386 55.0
HFD3_k127_6962592_0 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 425.0
HFD3_k127_6962592_1 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 306.0
HFD3_k127_6962592_2 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003545 259.0
HFD3_k127_696424_0 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008633 280.0
HFD3_k127_696424_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000134 280.0
HFD3_k127_696424_2 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000002302 131.0
HFD3_k127_6973581_0 esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001715 278.0
HFD3_k127_6973581_1 dehydrogenase complex catalyzes the overall conversion of - - - 0.000000000000000000000000000000000000000003435 167.0
HFD3_k127_6973581_2 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.000000000000000001559 88.0
HFD3_k127_6981310_0 oxoglutarate dehydrogenase (succinyl-transferring) activity K00164,K01616 GO:0000287,GO:0003674,GO:0003824,GO:0004591,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016624,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0019842,GO:0022900,GO:0030312,GO:0030976,GO:0032991,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0048037,GO:0050439,GO:0050662,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234 1.2.4.2,4.1.1.71 0.0 1205.0
HFD3_k127_6981310_1 Domain of unknown function (DUF5122) beta-propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000006488 249.0
HFD3_k127_6981310_2 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000738 168.0
HFD3_k127_6981310_3 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000001202 121.0
HFD3_k127_6981310_4 Belongs to the glycosyl hydrolase 32 family K00692 - 2.4.1.10 0.00000000000000008134 95.0
HFD3_k127_7001591_0 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 389.0
HFD3_k127_7001591_1 IstB-like ATP binding protein K02315 - - 0.0000000000000000000000000000000000000000000000000000000000000003156 229.0
HFD3_k127_7001591_2 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.00000000000000000000000000000000000000000000000000001455 195.0
HFD3_k127_7014032_0 Amidohydrolase family K01464 - 3.5.2.2 6.544e-202 638.0
HFD3_k127_7014032_1 Penicillin amidase K01434 - 3.5.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 583.0
HFD3_k127_7014032_2 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 366.0
HFD3_k127_7014032_3 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000001127 221.0
HFD3_k127_7014032_4 GTP cyclohydrolase II - - - 0.000000000000000000000000000000000000000000000000000000001813 204.0
HFD3_k127_7016914_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 1.305e-202 646.0
HFD3_k127_7016914_1 Belongs to the PdxA family K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004846 295.0
HFD3_k127_7016914_2 response regulator - - - 0.00000000000000000000004046 114.0
HFD3_k127_7018854_0 RNA polymerase sigma-54 factor K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 368.0
HFD3_k127_7018854_1 ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 299.0
HFD3_k127_7018854_2 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005227 256.0
HFD3_k127_7018854_3 Arginase family K01476 - 3.5.3.1 0.00000000000000000000000000000000000000000000000000000000000009648 224.0
HFD3_k127_7018854_4 PTS system fructose IIA component K02793,K02794,K02821 - 2.7.1.191,2.7.1.194 0.00000000000000000000000000000000001027 140.0
HFD3_k127_7018854_5 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000000000000000364 114.0
HFD3_k127_7018854_6 lipopolysaccharide transport K09774 - - 0.0000000000000000000000578 116.0
HFD3_k127_7018854_7 single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.0000000000000000000003083 100.0
HFD3_k127_7018854_8 Phosphocarrier protein HPR K11189 - - 0.0000000000008578 71.0
HFD3_k127_7043707_0 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000002183 146.0
HFD3_k127_7043707_1 MgtE intracellular N domain - - - 0.0000000000000000000000000000004806 126.0
HFD3_k127_707894_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 1.122e-232 735.0
HFD3_k127_707894_1 Tricorn protease C1 domain K08676 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007771 328.0
HFD3_k127_707894_2 PFAM beta-lactamase - - - 0.0000000000000000000000000000000000000000003844 173.0
HFD3_k127_7092350_0 glutamate-1-semialdehyde 2,1-aminomutase activity K01845 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016853,GO:0016866,GO:0016869,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042286,GO:0042440,GO:0042802,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008154 551.0
HFD3_k127_7092350_1 coproporphyrinogen oxidase activity K02495 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 547.0
HFD3_k127_7092350_2 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006937 459.0
HFD3_k127_7092350_3 Flavin containing amine oxidoreductase K00231,K14266 - 1.14.19.9,1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 349.0
HFD3_k127_7092350_4 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006780,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046394,GO:0046483,GO:0046501,GO:0046502,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005821 339.0
HFD3_k127_7092350_5 ferrochelatase activity K01772 GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009314,GO:0009416,GO:0009628,GO:0009987,GO:0016020,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0050896,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005367 336.0
HFD3_k127_7092350_6 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.00000000000000000000000000000000000214 143.0
HFD3_k127_7092350_7 Protein of unknown function (DUF2934) - - - 0.00000000000000001203 90.0
HFD3_k127_7141070_0 Flavin containing amine oxidoreductase K00274 - 1.4.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000797 363.0
HFD3_k127_7141070_1 hydrolase activity, hydrolyzing N-glycosyl compounds - - - 0.00000000000000000000000000000000000000000001444 166.0
HFD3_k127_7141070_2 - - - - 0.00000000000000000000000000000000523 138.0
HFD3_k127_7145608_0 with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine K01658,K01664 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000008076 259.0
HFD3_k127_7145608_1 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000004593 205.0
HFD3_k127_7155846_0 Peptide methionine sulfoxide reductase K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000002706 229.0
HFD3_k127_7155846_1 Translation initiation inhibitor, yjgF family K15067 - 3.5.99.5 0.0000000000000000000000000000000000000000000000000000000000000279 217.0
HFD3_k127_7155846_2 DoxX - - - 0.0000000000000000000000000000000000000000000000000003362 188.0
HFD3_k127_7155846_3 Cleaves the N-terminal amino acid of tripeptides K01258 - 3.4.11.4 0.000000000000000002091 85.0
HFD3_k127_7155846_4 alcohol dehydrogenase K00002,K13979 - 1.1.1.2 0.00000000000000002031 83.0
HFD3_k127_7172072_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 336.0
HFD3_k127_7172072_1 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000646 231.0
HFD3_k127_7172072_2 - K07018 - - 0.0000000000000000000000000000000000000009065 156.0
HFD3_k127_7172072_3 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000001716 136.0
HFD3_k127_7172072_4 Thioesterase superfamily K10806 - - 0.0000000000000000000000000007125 117.0
HFD3_k127_7172072_5 Sporulation protein SPS19 K13237 GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005782,GO:0006082,GO:0006629,GO:0006631,GO:0007049,GO:0008150,GO:0008152,GO:0008670,GO:0009056,GO:0009062,GO:0009653,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019953,GO:0022402,GO:0022413,GO:0022414,GO:0030154,GO:0030435,GO:0030437,GO:0031907,GO:0031974,GO:0032502,GO:0032505,GO:0032787,GO:0034293,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043934,GO:0043935,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0046395,GO:0048468,GO:0048646,GO:0048856,GO:0048869,GO:0051321,GO:0051704,GO:0055114,GO:0070013,GO:0071704,GO:0072329,GO:1901575,GO:1903046 1.3.1.34 0.0000000007188 60.0
HFD3_k127_71930_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005872 408.0
HFD3_k127_71930_1 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000002782 181.0
HFD3_k127_71930_2 Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites) K03653 - 4.2.99.18 0.00000000000000000000000000000000000008698 150.0
HFD3_k127_71930_3 zinc-ribbon domain - - - 0.0001246 53.0
HFD3_k127_7234338_0 CbbQ/NirQ/NorQ C-terminal K04748 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 374.0
HFD3_k127_7234338_1 hydrolase activity, hydrolyzing N-glycosyl compounds - - - 0.000000000000000000000000000000000000000000000000000000006136 212.0
HFD3_k127_7234338_2 Sortilin, neurotensin receptor 3, - - - 0.0000000000000000000000000000000000000000000001592 178.0
HFD3_k127_7234338_3 Acetyltransferase (GNAT) domain - GO:0003674,GO:0003824,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747 - 0.00000000000000000000000000000000000000000018 163.0
HFD3_k127_7234338_4 Transposase - - - 0.00000000000000000000000000000000000000001617 162.0
HFD3_k127_7239174_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008964 293.0
HFD3_k127_7239174_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000001322 166.0
HFD3_k127_7239174_2 - - - - 0.000000000000000000000000000004225 121.0
HFD3_k127_7239174_3 Phage plasmid primase P4 family K06919 - - 0.00000000000000000000003541 113.0
HFD3_k127_7239174_4 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00000000000004352 74.0
HFD3_k127_7239174_5 - - - - 0.000001919 51.0
HFD3_k127_7245976_0 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 454.0
HFD3_k127_7245976_1 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000000000006706 210.0
HFD3_k127_7245976_2 PFAM Hemolysin-type calcium-binding repeat (2 copies) - - - 0.00000000000000001828 87.0
HFD3_k127_7256691_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 6.439e-305 973.0
HFD3_k127_7256691_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009547 478.0
HFD3_k127_7256691_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004682 311.0
HFD3_k127_7256691_3 Peptidylprolyl isomerase K03771 - 5.2.1.8 0.00000000000000000000000000007602 129.0
HFD3_k127_7256691_4 S4 RNA-binding domain - - - 0.00000000000000002367 85.0
HFD3_k127_7256691_5 Domain of unknown function (DUF4920) - - - 0.0000016 53.0
HFD3_k127_7259055_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006518 471.0
HFD3_k127_7259055_1 C-terminal, D2-small domain, of ClpB protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003677 436.0
HFD3_k127_7259055_10 - - - - 0.00000000000000000000003403 105.0
HFD3_k127_7259055_11 Belongs to the ompA family - - - 0.000000000000000000001347 101.0
HFD3_k127_7259055_12 Protein of unknown function (DUF541) K09807 - - 0.000000000000000000002192 102.0
HFD3_k127_7259055_13 - - - - 0.0000000000005495 71.0
HFD3_k127_7259055_2 PFAM Cys Met metabolism K01739,K01761 - 2.5.1.48,4.4.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 376.0
HFD3_k127_7259055_3 FtsJ-like methyltransferase K06442 GO:0000154,GO:0001510,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019835,GO:0019836,GO:0022613,GO:0031167,GO:0031640,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035821,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044003,GO:0044004,GO:0044085,GO:0044179,GO:0044237,GO:0044238,GO:0044260,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046483,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000002344 266.0
HFD3_k127_7259055_4 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000001413 264.0
HFD3_k127_7259055_5 Domain of unknown function (DUF374) K09778 - - 0.000000000000000000000000000000000000000000000105 179.0
HFD3_k127_7259055_6 PFAM low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000002658 163.0
HFD3_k127_7259055_7 phosphorelay signal transduction system K02488,K04757 - 2.7.11.1,2.7.7.65 0.0000000000000000000000000003931 124.0
HFD3_k127_7259055_8 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000000000239 111.0
HFD3_k127_7259055_9 von Willebrand factor, type A K07114 - - 0.00000000000000000000001533 113.0
HFD3_k127_7286848_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 7.209e-320 1012.0
HFD3_k127_7286848_1 Belongs to the ClpA ClpB family K03696 - - 1.865e-294 925.0
HFD3_k127_7286848_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII - - - 0.000000000000000000000000000000000007918 152.0
HFD3_k127_7286848_3 recA bacterial DNA recombination protein - - - 0.000000000000000000000000000000002646 137.0
HFD3_k127_7286848_4 Protein of unknown function (DUF1232) - - - 0.0000000000000000000000001029 114.0
HFD3_k127_7286848_5 PFAM Phosphate acetyl butaryl transferase K00625 GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.8 0.000000000000000007118 87.0
HFD3_k127_7335406_0 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 352.0
HFD3_k127_7335406_1 PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002907 264.0
HFD3_k127_7335406_2 - - - - 0.0000000000000000000000000000000000000000143 174.0
HFD3_k127_7335406_3 - - - - 0.00000000000000000000000000005773 124.0
HFD3_k127_7335406_4 Glycosyltransferase Family 4 - - - 0.000000000000000000000001328 119.0
HFD3_k127_7335406_5 MacB-like periplasmic core domain K02004 - - 0.0000000000000001182 89.0
HFD3_k127_7343124_0 Secreted protein containing N-terminal Zinc-dependent carboxypeptidase related domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 365.0
HFD3_k127_7347617_0 Polysaccharide biosynthesis protein K17716 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 445.0
HFD3_k127_7347617_1 RmlD substrate binding domain K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004036 287.0
HFD3_k127_7347617_2 Glycosyl transferases group 1 - - - 0.00000000000003419 74.0
HFD3_k127_7370333_0 SMART tyrosine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006117 296.0
HFD3_k127_7370333_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000006029 153.0
HFD3_k127_7370333_2 von Willebrand factor, type A - - - 0.0000000000000007214 83.0
HFD3_k127_7370333_3 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000001647 68.0
HFD3_k127_7370333_4 PFAM Tetratricopeptide repeat - - - 0.000000003979 69.0
HFD3_k127_7370333_5 Putative zinc-finger - - - 0.00002838 55.0
HFD3_k127_7370790_0 Protein tyrosine kinase - - - 1.088e-198 643.0
HFD3_k127_7370790_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 593.0
HFD3_k127_7370790_2 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005801 493.0
HFD3_k127_7370790_3 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 367.0
HFD3_k127_7370790_4 peroxiredoxin activity - - - 0.000000000000000000000000000000000000004016 153.0
HFD3_k127_7370790_5 Redoxin - - - 0.0000000000000000003679 96.0
HFD3_k127_7382641_0 PFAM Cys Met metabolism pyridoxal-phosphate-dependent K01739 - 2.5.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 474.0
HFD3_k127_7382641_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000009934 250.0
HFD3_k127_7382641_2 Cysteine dioxygenase type I - - - 0.0000001878 60.0
HFD3_k127_7417923_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003984 562.0
HFD3_k127_7417923_1 ABC transporter K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 477.0
HFD3_k127_7417923_2 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000002379 201.0
HFD3_k127_7417923_3 Domain of unknown function (DUF4115) K15539 - - 0.0000000000000003025 90.0
HFD3_k127_7417923_4 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.00000000000003027 83.0
HFD3_k127_7417923_5 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.00000000000008185 71.0
HFD3_k127_7419295_0 protein secretion by the type I secretion system K11085 - - 1.69e-197 626.0
HFD3_k127_7419295_1 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 297.0
HFD3_k127_7419295_2 Belongs to the glycosyl hydrolase 32 family K00692 - 2.4.1.10 0.00000000000000000000000000000000000000000000000000005943 207.0
HFD3_k127_7419295_3 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00966,K00973,K00992 GO:0000166,GO:0000270,GO:0000287,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0005488,GO:0006022,GO:0006040,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019752,GO:0030203,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044281,GO:0046872,GO:0070569,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.7.13,2.7.7.24,2.7.7.99 0.0000000000000000000000000000000000000000000003857 179.0
HFD3_k127_7419295_4 phosphotransferase related to Ser Thr protein kinases K07102 - 2.7.1.221 0.0000000000000000000000000000000000558 146.0
HFD3_k127_7423224_0 Cys/Met metabolism PLP-dependent enzyme K01760,K17217 - 4.4.1.1,4.4.1.2,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 499.0
HFD3_k127_7423224_1 Transcriptional regulator, LysR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008081 336.0
HFD3_k127_7423224_2 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000001918 188.0
HFD3_k127_7423224_3 NfeD-like C-terminal, partner-binding - - - 0.000000000001207 75.0
HFD3_k127_7423224_4 BON domain - - - 0.000000002539 66.0
HFD3_k127_7453826_0 Periplasmic component of the Tol biopolymer transport system K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005249 437.0
HFD3_k127_7453826_1 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000001084 224.0
HFD3_k127_7453826_2 Zn-dependent hydrolase, glyoxylase - - - 0.0000000000000000000000000000000000000000000000000005367 196.0
HFD3_k127_7453826_3 FAD binding domain K21401 - 1.3.99.38 0.00000000000000000000000006968 115.0
HFD3_k127_7467263_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 533.0
HFD3_k127_7467263_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009075 434.0
HFD3_k127_7467263_2 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000001721 185.0
HFD3_k127_7476474_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003581 430.0
HFD3_k127_7476474_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000705 236.0
HFD3_k127_7476474_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000002219 184.0
HFD3_k127_7476474_3 Acyl-ACP thioesterase K07107 - - 0.00000000000000000000000000000001714 130.0
HFD3_k127_7489407_0 Subtilase family K14645 GO:0005575,GO:0005576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 339.0
HFD3_k127_7489407_1 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 318.0
HFD3_k127_7489407_2 - - - - 0.00000000000000000000000000000000000000000000000000002256 208.0
HFD3_k127_7489407_3 Multicopper oxidase K22350 - 1.16.3.3 0.000000000000000000000000001653 114.0
HFD3_k127_7489407_4 RNA-binding - - - 0.0000000000000000007235 93.0
HFD3_k127_7489407_5 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000179 53.0
HFD3_k127_7492963_0 glutamine synthetase K01915 - 6.3.1.2 1.494e-207 654.0
HFD3_k127_7492963_1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01585 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008821 601.0
HFD3_k127_7492963_2 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 449.0
HFD3_k127_7492963_3 Belongs to the arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000001967 258.0
HFD3_k127_7492963_4 Deoxyhypusine synthase K00809 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000008246 226.0
HFD3_k127_7492963_5 Orotidine 5'-phosphate decarboxylase / HUMPS family K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.00000000000000000000000000000000000000000000000000003376 193.0
HFD3_k127_7492963_6 - - - - 0.000000000000000000000000000000000000000000000000004581 186.0
HFD3_k127_7492963_7 - - - - 0.000000000000000000000000331 111.0
HFD3_k127_7492963_8 - - - - 0.00000000006513 66.0
HFD3_k127_749694_0 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009095 351.0
HFD3_k127_749694_1 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.000000000000000000000000000000000000000000000000000000002615 203.0
HFD3_k127_749694_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000004456 171.0
HFD3_k127_749694_3 HAD-superfamily hydrolase, subfamily IIB - - - 0.000000000000000000000000000000000000008847 156.0
HFD3_k127_749694_4 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768,K09565 - 5.2.1.8 0.000000000000000000000000000000001936 139.0
HFD3_k127_7501374_0 PFAM Major facilitator superfamily MFS-1 - - - 0.000000000000000000000000000006563 134.0
HFD3_k127_7501374_1 lactate/malate dehydrogenase, NAD binding domain K00016 - 1.1.1.27 0.00000000000000000000000000003438 128.0
HFD3_k127_7501374_2 response to heat K03668,K09914 - - 0.00000000000001196 85.0
HFD3_k127_7501374_3 Belongs to the universal stress protein A family - - - 0.000003392 58.0
HFD3_k127_751195_0 PFAM Citrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 377.0
HFD3_k127_751195_1 Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Binds and recognizes a DNA motif (called the malT box) 5'-GGA TG GA-3' K03556 - - 0.0000000000000000000006314 109.0
HFD3_k127_7520221_0 DHH family K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000008555 259.0
HFD3_k127_7520221_1 - - - - 0.00000000000000000000000000000000000000000000000002962 188.0
HFD3_k127_7520221_2 PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP K19221 - 2.5.1.17 0.0000000000000000000000000000000000000000000001106 174.0
HFD3_k127_7520221_3 Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.000000000000000000000000006907 119.0
HFD3_k127_7521877_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007151 470.0
HFD3_k127_7521877_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006121 400.0
HFD3_k127_7521877_10 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000000000003543 205.0
HFD3_k127_7521877_11 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000000000000001524 186.0
HFD3_k127_7521877_12 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000006823 175.0
HFD3_k127_7521877_13 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000004123 172.0
HFD3_k127_7521877_14 Binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000000000001283 173.0
HFD3_k127_7521877_15 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000000000004473 161.0
HFD3_k127_7521877_16 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000004937 135.0
HFD3_k127_7521877_17 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000003022 124.0
HFD3_k127_7521877_18 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000004634 121.0
HFD3_k127_7521877_19 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.000000000000000000000003411 110.0
HFD3_k127_7521877_2 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 294.0
HFD3_k127_7521877_20 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000008016 106.0
HFD3_k127_7521877_21 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000003369 101.0
HFD3_k127_7521877_22 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000001838 85.0
HFD3_k127_7521877_23 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000000003219 75.0
HFD3_k127_7521877_24 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000008361 74.0
HFD3_k127_7521877_25 Ribosomal protein L30 K02907 - - 0.00000000000003107 74.0
HFD3_k127_7521877_3 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 292.0
HFD3_k127_7521877_4 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000954 273.0
HFD3_k127_7521877_5 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000001211 233.0
HFD3_k127_7521877_6 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000000000000000000000779 221.0
HFD3_k127_7521877_7 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000001303 216.0
HFD3_k127_7521877_8 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000000001379 217.0
HFD3_k127_7521877_9 Forms part of the polypeptide exit tunnel K02926 - - 0.000000000000000000000000000000000000000000000000000000008957 207.0
HFD3_k127_7523457_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006339 411.0
HFD3_k127_7523457_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 418.0
HFD3_k127_7523457_2 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000009004 149.0
HFD3_k127_7523457_3 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.00000000000006798 74.0
HFD3_k127_7523457_4 LVIVD repeat - - - 0.00004421 57.0
HFD3_k127_7524731_0 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000005553 233.0
HFD3_k127_7524731_1 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000004321 207.0
HFD3_k127_7524731_2 Chlorite dismutase - - - 0.00000000000000000000000000000000000000000000000000000002221 206.0
HFD3_k127_7524731_3 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000000000000000000000000000000000003319 179.0
HFD3_k127_7524731_4 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000007644 119.0
HFD3_k127_7524731_5 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000000001269 79.0
HFD3_k127_7524731_6 - - - - 0.0000006312 61.0
HFD3_k127_7531022_0 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005676 449.0
HFD3_k127_7531022_1 PFAM Citrate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002161 260.0
HFD3_k127_7531022_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000001075 188.0
HFD3_k127_7563986_0 Gram-negative bacterial TonB protein C-terminal - - - 0.00006316 54.0
HFD3_k127_7563986_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0001373 49.0
HFD3_k127_7570360_0 PFAM FAD linked oxidase domain protein - - - 4.759e-203 642.0
HFD3_k127_7570360_1 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 413.0
HFD3_k127_7570360_2 dioxygenase K15777 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0046566,GO:0051213,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004734 385.0
HFD3_k127_7570360_3 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000002486 92.0
HFD3_k127_7580396_0 FAD linked oxidase K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 426.0
HFD3_k127_7580396_1 DinB superfamily - - - 0.00000000000000000000000000000000000004293 148.0
HFD3_k127_7580396_2 - - - - 0.00000000000000000000000000000000004514 144.0
HFD3_k127_7580396_3 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309,K11102 - - 0.00000001093 59.0
HFD3_k127_7587595_0 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 540.0
HFD3_k127_7587595_1 Transport permease protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003712 382.0
HFD3_k127_7587595_2 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 347.0
HFD3_k127_7591522_0 Ion transport 2 domain protein K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001008 271.0
HFD3_k127_7591522_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000394 265.0
HFD3_k127_7591522_2 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000563 232.0
HFD3_k127_7591522_3 Polynucleotide kinase 3 phosphatase K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000004253 172.0
HFD3_k127_7591522_4 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000006391 145.0
HFD3_k127_7591522_5 Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) K05365 - 2.4.1.129,3.4.16.4 0.000000000000000000000000205 116.0
HFD3_k127_7591522_6 short-chain dehydrogenase reductase SDR K12454 - 5.1.3.10 0.0000000000000000000000007347 115.0
HFD3_k127_7591522_7 phosphorelay sensor kinase activity K02668 - 2.7.13.3 0.0000000000000001278 90.0
HFD3_k127_7594280_0 Polysulphide reductase, NrfD K00185 - - 2.642e-198 629.0
HFD3_k127_7594280_1 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005918 441.0
HFD3_k127_7594280_2 Protein of unknown function (DUF3341) - - - 0.00000000000000000000000000000000000000000000000000000001401 203.0
HFD3_k127_7594280_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000001617 204.0
HFD3_k127_7603000_0 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.000000000000000000000000000000000000000000000000000000393 204.0
HFD3_k127_7603000_1 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000000001751 191.0
HFD3_k127_7603000_2 YbbR-like protein - - - 0.0003034 50.0
HFD3_k127_7615747_0 ABC transporter K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008795 435.0
HFD3_k127_7615747_1 chlorophyll binding - - - 0.00000000000000000001271 97.0
HFD3_k127_7615747_2 Stress-induced protein - - - 0.0000000000000000005943 91.0
HFD3_k127_7655150_0 Sporulation protein SPS19 K13237 GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005782,GO:0006082,GO:0006629,GO:0006631,GO:0007049,GO:0008150,GO:0008152,GO:0008670,GO:0009056,GO:0009062,GO:0009653,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019953,GO:0022402,GO:0022413,GO:0022414,GO:0030154,GO:0030435,GO:0030437,GO:0031907,GO:0031974,GO:0032502,GO:0032505,GO:0032787,GO:0034293,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043934,GO:0043935,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0046395,GO:0048468,GO:0048646,GO:0048856,GO:0048869,GO:0051321,GO:0051704,GO:0055114,GO:0070013,GO:0071704,GO:0072329,GO:1901575,GO:1903046 1.3.1.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005322 289.0
HFD3_k127_7655150_1 HrcA protein C terminal domain K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000003773 245.0
HFD3_k127_7655150_2 nucleotide metabolic process - - - 0.0000000000000000000000000000000000000000000001013 177.0
HFD3_k127_7655150_3 Elongator protein 3, MiaB family, Radical SAM K03644 - 2.8.1.8 0.000000000000006727 75.0
HFD3_k127_7679326_0 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000001214 255.0
HFD3_k127_7679326_1 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 0.000000000000000000000000000000000000000002395 163.0
HFD3_k127_7679326_2 TIGRFAM Outer membrane assembly lipoprotein YfiO K05807 - - 0.000000000000000000000000000000000001178 156.0
HFD3_k127_7679326_3 PFAM PASTA domain - - - 0.0002179 51.0
HFD3_k127_7681306_0 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006335 557.0
HFD3_k127_7681306_1 Type II secretion system (T2SS), protein F K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 382.0
HFD3_k127_7681306_2 PFAM Type II secretion system protein E K02454,K02504,K02652 - - 0.0000000000000000000000000000000000001032 143.0
HFD3_k127_7686552_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006185 518.0
HFD3_k127_7686552_1 Belongs to the HpcH HpaI aldolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005141 369.0
HFD3_k127_7686552_2 Large family of predicted nucleotide-binding domains - - - 0.00000000000000000000000000000000000000000000003186 176.0
HFD3_k127_7686552_3 Domain of unknown function (DUF4440) - - - 0.0000000000000000000007556 101.0
HFD3_k127_7690253_0 aminopeptidase K01256 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 400.0
HFD3_k127_7690253_1 Peptidase M1, membrane alanine aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000002361 209.0
HFD3_k127_7711052_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005331 584.0
HFD3_k127_7711052_1 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines K01479,K12255 - 3.5.3.7,3.5.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000003311 266.0
HFD3_k127_7711052_2 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000008547 191.0
HFD3_k127_7711052_3 peptidyl-tyrosine sulfation - - - 0.000003374 59.0
HFD3_k127_771875_0 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 355.0
HFD3_k127_771875_1 Peptidase family M1 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005246 314.0
HFD3_k127_771875_2 Flavin containing amine oxidoreductase K00274 - 1.4.3.4 0.0000000000000000000000000001258 118.0
HFD3_k127_772693_0 Transcriptional regulator K21900 - - 0.0000000000000000001456 96.0
HFD3_k127_772693_1 Transcriptional regulator K07733 - - 0.00000000000000003541 87.0
HFD3_k127_772693_2 transcriptional regulator - - - 0.00000109 53.0
HFD3_k127_772693_3 NMT1-like family K02051 - - 0.000001277 57.0
HFD3_k127_7745146_0 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000415 279.0
HFD3_k127_7745146_1 COG0308 Aminopeptidase N - - - 0.000000000000000000000000000000000007869 141.0
HFD3_k127_7745146_2 Belongs to the bacterial histone-like protein family K03530 - - 0.0000000000000000000001473 102.0
HFD3_k127_7745146_3 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000009756 84.0
HFD3_k127_7748066_0 glucan 1,4-alpha-glucosidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000907 604.0
HFD3_k127_7748066_1 Transporter-associated region K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 424.0
HFD3_k127_7748066_2 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K13819 - - 0.0000000000000000000000001616 113.0
HFD3_k127_7748066_3 GDP-mannose mannosyl hydrolase activity K00974,K03574,K18445 - 2.7.7.72,3.6.1.55,3.6.1.61 0.0000000000000000000001312 102.0
HFD3_k127_7748066_4 Glutathione peroxidase K02199 - - 0.00000000000000000001284 100.0
HFD3_k127_785341_0 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004024 304.0
HFD3_k127_785341_1 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003871 265.0
HFD3_k127_785341_2 Protein of unknown function (DUF541) K09797 - - 0.0000000000000000000000000000000000000000000000000000000000000000002807 236.0
HFD3_k127_785341_3 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000004815 186.0
HFD3_k127_785341_4 - - - - 0.00000000000000000000000000000000000000568 158.0
HFD3_k127_785341_5 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.000000000000000000000000000000003233 132.0
HFD3_k127_785341_6 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000313 99.0
HFD3_k127_793123_0 PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.21.26 1.903e-298 931.0
HFD3_k127_793123_1 Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009958 398.0
HFD3_k127_801256_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1461.0
HFD3_k127_801256_1 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003509 582.0
HFD3_k127_801256_2 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000000000000000000000005759 134.0
HFD3_k127_801256_3 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000311 101.0
HFD3_k127_801256_4 RNA recognition motif - - - 0.0000000000000000403 82.0
HFD3_k127_801256_5 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.0000005263 51.0
HFD3_k127_817562_0 nucleic acid phosphodiester bond hydrolysis K07577 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 433.0
HFD3_k127_817562_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 323.0
HFD3_k127_817562_2 DNA repair exonuclease K03547 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002413 268.0
HFD3_k127_817562_3 ATP-dependent protease La (LON) domain K01338 - 3.4.21.53 0.000000000000000000000296 100.0
HFD3_k127_817562_4 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.000000008287 57.0
HFD3_k127_820000_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 598.0
HFD3_k127_820000_1 hydrolase, TatD family K03424 - - 0.000000000000000000000000000000027 129.0
HFD3_k127_820000_2 Peptidase, M28 - - - 0.00000000000000001043 85.0
HFD3_k127_820535_0 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 449.0
HFD3_k127_820535_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000002894 266.0
HFD3_k127_820535_2 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000004306 269.0
HFD3_k127_830976_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001056 264.0
HFD3_k127_830976_1 pfkB family carbohydrate kinase K18478 - 2.7.1.184 0.0000000000000000000000000000000000000000000000000000000000004277 222.0
HFD3_k127_830976_2 - K05826 - - 0.000003571 52.0
HFD3_k127_838603_0 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00756,K00758 - 2.4.2.2,2.4.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000871 419.0
HFD3_k127_838603_1 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.00000000000000000000000000000000000000000000008077 173.0
HFD3_k127_838603_2 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.0000000000000000000000000000001689 127.0
HFD3_k127_838603_3 ABC-type transport system, periplasmic component surface lipoprotein K07335 - - 0.000000000000000000000003706 105.0
HFD3_k127_84478_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 2.409e-242 757.0
HFD3_k127_84478_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006407 306.0
HFD3_k127_84478_2 Virulence factor BrkB K07058 - - 0.000000000000000000000000000000000000000000000183 178.0
HFD3_k127_845311_0 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007259 285.0
HFD3_k127_845311_1 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000002597 254.0
HFD3_k127_845311_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000001131 254.0
HFD3_k127_845311_3 PFAM Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000001327 244.0
HFD3_k127_845311_4 metalloendopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000004379 208.0
HFD3_k127_845311_5 Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000002175 203.0
HFD3_k127_845311_6 outer membrane autotransporter barrel domain protein - - - 0.0000000000000000000000000000751 125.0
HFD3_k127_845311_7 copper ion binding K03926 GO:0003674,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0008104,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0019899,GO:0022607,GO:0033036,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0046872,GO:0046914,GO:0051179,GO:0051259,GO:0051260,GO:0065003,GO:0071840 - 0.0000000000000000000005165 98.0
HFD3_k127_847429_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 1.392e-242 777.0
HFD3_k127_847429_1 Polysaccharide biosynthesis/export protein K01991 - - 0.00000000000000000000006264 111.0
HFD3_k127_847429_2 protein involved in exopolysaccharide biosynthesis K16554 - - 0.00000000000000000000995 106.0
HFD3_k127_853356_0 3,4-dihydroxy-2-butanone 4-phosphate synthase K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 423.0
HFD3_k127_853356_1 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00000000000000000000000000000000000000000000000000000004175 227.0
HFD3_k127_853356_2 Modulates RecA activity K03565,K19002 GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0019899,GO:0031668,GO:0033554,GO:0043086,GO:0044092,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496 2.4.1.337 0.00000000000001908 79.0
HFD3_k127_853356_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0002224 51.0
HFD3_k127_860230_0 Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000003789 192.0
HFD3_k127_860230_1 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000004335 193.0
HFD3_k127_860230_2 Peptidase S46 - - - 0.0000000000000000000000000000000000000000009466 166.0
HFD3_k127_860230_3 Class III cytochrome C family - - - 0.000003205 56.0
HFD3_k127_872323_0 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 0.0 1091.0
HFD3_k127_872323_1 PFAM Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000001513 153.0
HFD3_k127_879039_0 Saccharopine dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006361 368.0
HFD3_k127_879039_1 MatE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 335.0
HFD3_k127_879039_2 Serine threonine protein kinase K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001568 294.0
HFD3_k127_879039_3 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000001871 199.0
HFD3_k127_879039_4 DinB family - - - 0.0000000000000000000000000000000000000000001356 164.0
HFD3_k127_879039_5 - - - - 0.000000000000000000000000000000004291 132.0
HFD3_k127_879039_6 PFAM Protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000009333 140.0
HFD3_k127_879039_7 cAMP biosynthetic process - - - 0.000000000000000004268 98.0
HFD3_k127_879039_8 Cupin 2, conserved barrel domain protein K16953,K19547 - 4.4.1.3,5.3.3.19 0.0007889 49.0
HFD3_k127_882625_0 - - - - 0.000000000000000000000000005396 119.0
HFD3_k127_882625_1 - - - - 0.00000000005195 67.0
HFD3_k127_886149_0 PFAM ResB family protein K07399 - - 0.000000000000000000000000000000000000000221 168.0
HFD3_k127_886149_1 PFAM cytochrome c class III - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000007737 80.0
HFD3_k127_930412_0 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 534.0
HFD3_k127_930412_1 Prolyl oligopeptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000007095 231.0
HFD3_k127_930412_2 Prolyl oligopeptidase family - - - 0.000000001723 62.0
HFD3_k127_939602_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003342 263.0
HFD3_k127_939602_1 PFAM glycosyl transferase family 39 - - - 0.000000000000000000000000000000000000000000000000787 195.0
HFD3_k127_939602_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.0000000000000000000000000000000006283 134.0
HFD3_k127_977764_0 Two component regulator propeller - - - 0.00000000000000000000000000000000000002757 166.0
HFD3_k127_977764_1 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000003593 136.0
HFD3_k127_977764_2 - - - - 0.000000000000000001684 96.0
HFD3_k127_994880_0 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 362.0
HFD3_k127_994880_1 Surface antigen variable number - - - 0.0000000000000000000000000000000000000000000000000000754 213.0