Overview

ID MAG01679
Name HFD3_bin.18
Sample SMP0045
Taxonomy
Kingdom Bacteria
Phylum Verrucomicrobiota
Class Verrucomicrobiia
Order Limisphaerales
Family JADJPG01
Genus
Species
Assembly information
Completeness (%) 66.4
Contamination (%) 0.34
GC content (%) 66.0
N50 (bp) 7,861
Genome size (bp) 3,948,649

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2844

Gene name Description KEGG GOs EC E-value Score Sequence
HFD3_k127_1000890_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008665 505.0
HFD3_k127_1000890_2 Sigma-70, region 4 - - - 0.0000000000000000000000000000000000000000000000007387 185.0
HFD3_k127_1000890_3 Concanavalin A-like lectin/glucanases superfamily - - - 0.000000000006094 81.0
HFD3_k127_1019032_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 603.0
HFD3_k127_1019032_1 May be involved in the transport of PQQ or its precursor to the periplasm - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 414.0
HFD3_k127_1019032_2 peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000044 289.0
HFD3_k127_1019032_3 3-dehydroquinate synthase K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000009233 160.0
HFD3_k127_1022157_0 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 581.0
HFD3_k127_1022157_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003844 478.0
HFD3_k127_1022157_2 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 403.0
HFD3_k127_1022157_3 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 336.0
HFD3_k127_1022157_4 SIS domain K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000225 271.0
HFD3_k127_1022157_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001167 237.0
HFD3_k127_1034959_0 TonB-dependent receptor K02014 - - 1.293e-199 645.0
HFD3_k127_1034959_1 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 598.0
HFD3_k127_1034959_2 PFAM lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 456.0
HFD3_k127_1034959_3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006654 436.0
HFD3_k127_1034959_4 cytochrome - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 432.0
HFD3_k127_1034959_5 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003454 249.0
HFD3_k127_1034959_6 response regulator K02282,K07705 - - 0.0000000000000000000000000001376 120.0
HFD3_k127_1034959_7 Domain of unknown function (DUF4154) - - - 0.00000000000000002226 93.0
HFD3_k127_1063446_0 Domain of unknown function (DUF5122) beta-propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001263 285.0
HFD3_k127_1063446_1 Hemolysin-type calcium-binding repeat (2 copies) - - - 0.00000000000000000000000000000001702 148.0
HFD3_k127_1085316_0 polysaccharide deacetylase K09992 - - 0.0 1120.0
HFD3_k127_1085316_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 8.038e-226 710.0
HFD3_k127_1085316_2 PFAM FAD dependent oxidoreductase K00111 - 1.1.5.3 5.139e-211 667.0
HFD3_k127_1085316_3 Transporter associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001113 230.0
HFD3_k127_1085316_5 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000000000002378 124.0
HFD3_k127_1085316_6 Protein of unknown function (DUF3738) - - - 0.000000001733 69.0
HFD3_k127_1087841_0 CotH kinase protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 365.0
HFD3_k127_1087841_1 - - - - 0.000002041 51.0
HFD3_k127_1100276_0 PFAM Pyrrolo-quinoline quinone K00117 - 1.1.5.2 1.877e-219 704.0
HFD3_k127_1100276_1 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 401.0
HFD3_k127_1100276_2 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 403.0
HFD3_k127_1100276_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 299.0
HFD3_k127_1100276_4 Beta-lactamase superfamily domain K06167 - 3.1.4.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005747 271.0
HFD3_k127_1100276_5 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004653 251.0
HFD3_k127_1100276_6 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000002053 243.0
HFD3_k127_1100276_7 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000005206 93.0
HFD3_k127_1102568_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1043.0
HFD3_k127_1102568_1 Bacterial Ig-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002714 413.0
HFD3_k127_1102568_2 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000002762 152.0
HFD3_k127_1102568_3 PFAM Hemolysin-type calcium-binding repeat (2 copies) - - - 0.000000000000000000001734 113.0
HFD3_k127_1102568_4 Fibronectin type 3 domain - - - 0.000000000000000002859 102.0
HFD3_k127_1102568_5 pilus organization K02305 - - 0.00000006626 68.0
HFD3_k127_1102568_6 response to antibiotic - - - 0.0000001509 67.0
HFD3_k127_1111807_0 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 352.0
HFD3_k127_1111807_1 TIGRFAM conserved repeat domain - - - 0.0000000000000000000000000000000000000000000000000000000000003495 244.0
HFD3_k127_1111807_2 Haemolysin-type calcium-binding repeat (2 copies) K01406 - 3.4.24.40 0.000000000000000000000000000000000002898 162.0
HFD3_k127_1111807_3 Conserved repeat domain - - - 0.00000000000000000000000000001801 139.0
HFD3_k127_1111807_4 Fibronectin type 3 domain K01179,K01361,K01637,K01729,K09942,K20276 - 3.2.1.4,3.4.21.96,4.1.3.1,4.2.2.3 0.000000000004487 82.0
HFD3_k127_1111807_5 Glucose / Sorbosone dehydrogenase - - - 0.000000151 67.0
HFD3_k127_1122508_0 Cytochrome c - - - 1.284e-220 717.0
HFD3_k127_1122508_1 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003183 568.0
HFD3_k127_1122508_2 TIGRFAM Por secretion system C-terminal sorting domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 431.0
HFD3_k127_1122508_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02022,K16922,K20345 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004185 409.0
HFD3_k127_1122508_4 domain, Protein - - - 0.0000000000000000000000002212 123.0
HFD3_k127_1122508_5 Pkd domain - - - 0.000000000000000004483 99.0
HFD3_k127_1122508_6 Protein of unknown function (DUF721) - - - 0.00000000006253 67.0
HFD3_k127_1122508_7 Putative cell wall binding repeat 2 - - - 0.000000006867 69.0
HFD3_k127_1132787_0 CotH kinase protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001289 312.0
HFD3_k127_1132787_1 CotH kinase protein - - - 0.000000000000000000000000000000000002324 162.0
HFD3_k127_1132787_2 CotH kinase protein - - - 0.0000000000000000000000000001444 132.0
HFD3_k127_1132787_3 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000002749 112.0
HFD3_k127_1132787_4 Spore coat protein CotH - - - 0.00000000000003509 89.0
HFD3_k127_1132787_5 cellulose binding K13735 - - 0.00000007565 65.0
HFD3_k127_122394_0 metallopeptidase activity K01993,K13408,K16922 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 552.0
HFD3_k127_122394_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02004,K07798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004155 417.0
HFD3_k127_122394_2 efflux transmembrane transporter activity K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001267 272.0
HFD3_k127_122394_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K13888 - - 0.0000000000000000000000001205 120.0
HFD3_k127_1247784_0 Prokaryotic N-terminal methylation motif - - - 0.0004353 51.0
HFD3_k127_127032_0 Helicase associated domain (HA2) Add an annotation K03578 - 3.6.4.13 6.384e-239 756.0
HFD3_k127_127032_1 mandelate racemase muconate lactonizing K08323 - 4.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 495.0
HFD3_k127_127032_2 Lactonase, 7-bladed beta-propeller - - - 0.000000000000000000000000000000000000000000000000000000000000008053 232.0
HFD3_k127_127032_3 PFAM S23 ribosomal protein - - - 0.0000000000000000000000005772 109.0
HFD3_k127_128873_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 467.0
HFD3_k127_128873_1 hydrolase activity, acting on ester bonds K07051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 427.0
HFD3_k127_128873_2 myo-inosose-2 dehydratase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002309 280.0
HFD3_k127_128873_3 - - - - 0.000000000000000000000000000000132 128.0
HFD3_k127_128873_5 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0002211 53.0
HFD3_k127_1360737_0 Transglutaminase-like superfamily K04771,K08372 - 3.4.21.107 4.204e-206 666.0
HFD3_k127_1360737_1 Spore coat protein CotH K01216,K07004 - 3.2.1.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005236 602.0
HFD3_k127_1360737_2 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000008377 234.0
HFD3_k127_1360737_3 twin-arginine translocation pathway signal protein K07093 - - 0.0000000000000000000000000000000000000000000000000000328 218.0
HFD3_k127_1360737_5 nuclear chromosome segregation - - - 0.0000000000002491 70.0
HFD3_k127_1360737_6 Peptidase S8 - - - 0.0000001114 67.0
HFD3_k127_1379076_0 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004927 424.0
HFD3_k127_1379076_1 Heparinase II/III-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000013 267.0
HFD3_k127_1379076_2 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000004035 149.0
HFD3_k127_1384830_0 CotH kinase protein K02487,K12543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009187 513.0
HFD3_k127_1384830_1 Spore coat protein CotH K01216,K07004 - 3.2.1.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000001113 302.0
HFD3_k127_1384830_2 Immunoglobulin - - - 0.000000000000000000000000001705 133.0
HFD3_k127_1384830_3 alkaline phosphatase - - - 0.00000000001596 80.0
HFD3_k127_139279_0 - - - - 0.0000000000000000000000000000000000000000000008374 188.0
HFD3_k127_139279_1 Regulator of chromosome condensation (RCC1) repeat K20276 - - 0.00000000000000000000000000119 130.0
HFD3_k127_141026_0 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006142 322.0
HFD3_k127_141026_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000003315 258.0
HFD3_k127_141026_2 PFAM nuclear protein SET K07117 - - 0.00000000000000000000000000000000000004405 151.0
HFD3_k127_1417889_0 Sodium:solute symporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006448 460.0
HFD3_k127_1417889_1 Spore coat protein CotH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 369.0
HFD3_k127_1417889_2 Spore coat protein CotH K01216,K07004 - 3.2.1.73 0.0000000000000000000000000000000000000000000000000000000000000000001556 263.0
HFD3_k127_1417889_3 Arginosuccinate synthase K01940 - 6.3.4.5 0.000000000000000000000000000000000000001069 149.0
HFD3_k127_1417889_4 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.000000000000007503 74.0
HFD3_k127_1420016_0 Planctomycete cytochrome C - - - 2.353e-313 983.0
HFD3_k127_1420016_1 thiamine pyrophosphate protein TPP binding domain protein K01652 - 2.2.1.6 5.382e-236 747.0
HFD3_k127_1420016_2 Protein of unknown function (DUF1501) - - - 1.23e-218 682.0
HFD3_k127_1420016_3 Protein of unknown function (DUF1501) - - - 9.319e-212 664.0
HFD3_k127_1420016_4 Planctomycete cytochrome C - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 548.0
HFD3_k127_1420016_5 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004917 515.0
HFD3_k127_1420016_6 Protein of unknown function (DUF1501) - - - 0.00000000000003201 76.0
HFD3_k127_1420016_7 RDD family - - - 0.000000000001006 82.0
HFD3_k127_1429962_0 Phosphoenolpyruvate hydrolase-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000553 472.0
HFD3_k127_1429962_1 HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 311.0
HFD3_k127_1429962_2 Copper binding periplasmic protein CusF K07152 - - 0.0000000000000000000000000000000000000000001277 173.0
HFD3_k127_1440876_0 Belongs to the TPP enzyme family K07004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 348.0
HFD3_k127_1440876_1 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.00000000000000000000000000000005116 148.0
HFD3_k127_1440876_2 Belongs to the ompA family K03286 - - 0.000000000000001064 94.0
HFD3_k127_1450679_0 Belongs to the glycosyl hydrolase 43 family K22350 - 1.16.3.3 1.778e-202 693.0
HFD3_k127_1450679_1 Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 317.0
HFD3_k127_1450679_2 Fibronectin type 3 domain - - - 0.00000000000000000000000002569 128.0
HFD3_k127_1462192_0 FtsX-like permease family - - - 1.358e-250 812.0
HFD3_k127_1462192_1 - - - - 0.000000000000000000000000000000000000000000000000005533 188.0
HFD3_k127_1462192_2 Protein of unknown function (DUF1549) - - - 0.0000000009938 63.0
HFD3_k127_1464567_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 2.469e-287 897.0
HFD3_k127_1464567_1 COG2706 3-carboxymuconate cyclase K07404 - 3.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 426.0
HFD3_k127_1464567_2 Ca-dependent carbohydrate-binding module xylan-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 328.0
HFD3_k127_1464567_3 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000001244 219.0
HFD3_k127_1464567_4 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.000000000000000000000000000000000000000000005563 173.0
HFD3_k127_1464567_5 - - - - 0.000000000000000000000000006893 118.0
HFD3_k127_1464567_7 Glycosyl transferases group 1 - - - 0.00000000000000000000004829 112.0
HFD3_k127_1464567_8 heptosyl III transferase WaaQ (Glycosyl transferase, family 9) K02849 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0071704,GO:0071967,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.000000000000000003193 97.0
HFD3_k127_1464567_9 PFAM Glycosyl transferase family 2 - - - 0.0000000000003591 81.0
HFD3_k127_146967_0 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 494.0
HFD3_k127_146967_1 transport system, ATPase K10441 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008584 387.0
HFD3_k127_146967_2 Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 332.0
HFD3_k127_146967_3 Branched-chain amino acid transport system / permease component K10440,K10553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004579 285.0
HFD3_k127_1480470_0 X-Pro dipeptidyl-peptidase (S15 family) - - - 6.004e-221 709.0
HFD3_k127_1480470_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 425.0
HFD3_k127_1480470_10 - - - - 0.0000000000000000000005282 108.0
HFD3_k127_1480470_11 cellulose binding - - - 0.00007828 46.0
HFD3_k127_1480470_12 pathogenesis - - - 0.0001335 55.0
HFD3_k127_1480470_2 radical SAM K06871 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 333.0
HFD3_k127_1480470_3 regulation of response to stimulus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 328.0
HFD3_k127_1480470_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 320.0
HFD3_k127_1480470_5 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 317.0
HFD3_k127_1480470_6 regulation of response to stimulus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 305.0
HFD3_k127_1480470_7 Psort location Cytoplasmic, score 8.96 - - - 0.000000000000000000000000000000000000000000000000000000000000002223 232.0
HFD3_k127_1480470_8 Di-glucose binding within endoplasmic reticulum - - - 0.00000000000000000000000000000000000000000000000001846 200.0
HFD3_k127_1480470_9 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.00000000000000000000000000000000007761 142.0
HFD3_k127_148465_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008356 343.0
HFD3_k127_148465_1 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000001075 180.0
HFD3_k127_1488973_0 response to antibiotic - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004304 452.0
HFD3_k127_1488973_1 Regulator of chromosome condensation (RCC1) repeat - - - 0.0000003616 64.0
HFD3_k127_14911_0 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008018 586.0
HFD3_k127_14911_1 SPFH domain-Band 7 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 508.0
HFD3_k127_14911_2 tRNA wobble cytosine modification - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 501.0
HFD3_k127_14911_3 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000000000000001807 200.0
HFD3_k127_14911_4 - - - - 0.0000000000000000000000000000009881 130.0
HFD3_k127_14911_5 - - - - 0.000000000000000000000000001949 115.0
HFD3_k127_1501626_0 Acyl transferase domain in polyketide synthase (PKS) enzymes. - - - 0.0 1066.0
HFD3_k127_1501626_1 AMP-binding enzyme C-terminal domain K02364 - 6.3.2.14 2.661e-261 842.0
HFD3_k127_1513407_0 WD domain, G-beta repeat - - - 1.437e-308 992.0
HFD3_k127_1513407_1 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 3.775e-234 747.0
HFD3_k127_1513407_2 PFAM ketose-bisphosphate aldolase, class-II K01624 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006174 384.0
HFD3_k127_1513407_3 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 291.0
HFD3_k127_1513407_4 Belongs to the phosphoglycerate mutase family K15634 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000004171 204.0
HFD3_k127_1513407_5 Protein of unknown function (DUF2975) - - - 0.00000000000000000000000000000001209 137.0
HFD3_k127_1513407_6 negative regulation of transcription, DNA-templated - - - 0.00000000000000000000000000000001941 127.0
HFD3_k127_1533458_0 TIGRFAM autotransporter-associated beta strand repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000006166 232.0
HFD3_k127_1535705_0 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 542.0
HFD3_k127_1535705_1 SdrD B-like domain - - - 0.0000000000000000000000000000000000006293 153.0
HFD3_k127_1535705_2 cell cycle K05589,K12065,K13052 - - 0.00001726 51.0
HFD3_k127_1535705_3 Yip1 domain - - - 0.00001842 55.0
HFD3_k127_1535705_4 Belongs to the peptidase S8 family K12287,K12516,K20276 - - 0.0002561 53.0
HFD3_k127_1554767_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006391 550.0
HFD3_k127_1554767_1 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 443.0
HFD3_k127_1554767_2 GntP family permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 327.0
HFD3_k127_1554767_3 Subtilase family K17734 - - 0.0000000000000000000000000000000000000000000000001022 207.0
HFD3_k127_1562334_0 Exodeoxyribonuclease V, gamma subunit K03583 - 3.1.11.5 1.045e-221 734.0
HFD3_k127_1562334_1 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008553 638.0
HFD3_k127_1562334_2 glucosamine-6-phosphate deaminase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 534.0
HFD3_k127_1562334_3 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008079 464.0
HFD3_k127_1562334_4 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 317.0
HFD3_k127_1562334_5 RNase_H superfamily K06877 - - 0.00000000000000000000000000000000000000000000000000000000000000004928 228.0
HFD3_k127_1587375_0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004333 574.0
HFD3_k127_1587375_1 ferrous iron binding K06990,K09141,K15755 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008595 377.0
HFD3_k127_1587375_2 Glycerophosphoryl diester phosphodiesterase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000126 279.0
HFD3_k127_1587375_3 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.00000000000000000000000000000000000000000000000000000000000000008406 236.0
HFD3_k127_1587375_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000000000000000001336 203.0
HFD3_k127_1587375_5 Sigma-70, region 4 - - - 0.00000000000000000000000000000000000000000005736 168.0
HFD3_k127_1587375_6 AntiSigma factor - - - 0.000000000000000000000004129 112.0
HFD3_k127_1588621_0 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005084 320.0
HFD3_k127_1588621_1 Transfers electrons from cytochrome c551 to cytochrome oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 317.0
HFD3_k127_1588621_2 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000001101 186.0
HFD3_k127_1592743_0 Acetyl xylan esterase (AXE1) - - - 1.365e-207 670.0
HFD3_k127_1592743_1 COGs COG0471 Di- and tricarboxylate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 525.0
HFD3_k127_1601428_0 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008869 515.0
HFD3_k127_1601428_1 pfkB family carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 410.0
HFD3_k127_1601428_10 Rdx family K07401 - - 0.000000000119 63.0
HFD3_k127_1601428_2 Xylose operon regulatory protein K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 322.0
HFD3_k127_1601428_3 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K01802 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004211 275.0
HFD3_k127_1601428_4 Mechanosensitive ion channel K03442 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001315 274.0
HFD3_k127_1601428_5 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000004162 229.0
HFD3_k127_1601428_6 COG0500 SAM-dependent methyltransferases - - - 0.000000000000000000000000000000000000000000000000000000002246 211.0
HFD3_k127_1601428_7 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000001053 143.0
HFD3_k127_1601428_8 Passenger-associated-transport-repeat - - - 0.0000000000000000000000009162 121.0
HFD3_k127_1601428_9 3-demethylubiquinone-9 3-O-methyltransferase activity K18827 - 2.1.1.294,2.7.1.181 0.000000000003726 76.0
HFD3_k127_1604191_0 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007283 536.0
HFD3_k127_1604191_1 gluconolactonase K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005699 430.0
HFD3_k127_1604191_2 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 363.0
HFD3_k127_1604191_3 PFAM lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000004357 207.0
HFD3_k127_1610939_0 C-terminal region of aryl-sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009734 566.0
HFD3_k127_1610939_1 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 547.0
HFD3_k127_1610939_2 Protein of unknown function (DUF1593) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 462.0
HFD3_k127_1610939_3 Dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003668 423.0
HFD3_k127_1610939_4 Nucleoside recognition - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 385.0
HFD3_k127_1610939_5 3-demethylubiquinone-9 3-methyltransferase K04750 - - 0.0000000000000000000000000000000000000000000000000000000000003333 214.0
HFD3_k127_1610939_6 Hydrolases of the alpha beta superfamily K06889 - - 0.0000000000000000000000000000000000000000000000000000000000003826 222.0
HFD3_k127_1610939_8 Addiction module toxin, RelE StbE family - - - 0.00000000000000000000000000000003748 132.0
HFD3_k127_1610939_9 PurA ssDNA and RNA-binding protein - - - 0.0000000000000001093 83.0
HFD3_k127_166606_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 578.0
HFD3_k127_166606_1 Oxidoreductase family, NAD-binding Rossmann fold K00118 - 1.1.99.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006247 479.0
HFD3_k127_166606_2 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004717 418.0
HFD3_k127_166606_3 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004086 289.0
HFD3_k127_166606_4 Aminomethyltransferase folate-binding domain K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000003282 192.0
HFD3_k127_166606_5 PFAM PfkB domain protein - - - 0.0000000000000000000000000000000000000000000000001422 198.0
HFD3_k127_166606_6 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000000251 168.0
HFD3_k127_166606_7 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000197 153.0
HFD3_k127_166606_8 Phospholipid N-methyltransferase - - - 0.000000000000000000000000000000000001321 146.0
HFD3_k127_1670299_0 Protein of unknown function (DUF1501) - - - 2.271e-244 762.0
HFD3_k127_1670299_1 Spore coat protein CotH K01216,K07004 - 3.2.1.73 0.000000000000000000000000000000000000000000000000000000000002141 238.0
HFD3_k127_1670299_2 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000003834 200.0
HFD3_k127_1670299_3 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000005467 200.0
HFD3_k127_1670299_4 kinase activity K02848,K07178,K19302 - 2.7.11.1,3.6.1.27 0.000000000000000001964 98.0
HFD3_k127_1670299_5 CotH kinase protein - - - 0.000000000000000004602 100.0
HFD3_k127_1670299_6 1,4-alpha-glucan branching enzyme activity - - - 0.000000000000003178 79.0
HFD3_k127_1670299_7 sam-dependent methyltransferase - - - 0.000000000000009078 87.0
HFD3_k127_1670299_8 CotH kinase protein - - - 0.000000000005933 80.0
HFD3_k127_1691736_0 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 472.0
HFD3_k127_1691736_1 TIGRFAM Methylated-DNA- protein -cysteine S-methyltransferase, DNA binding K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 430.0
HFD3_k127_1691736_2 - - - - 0.0000000000000000000000000000000000006936 149.0
HFD3_k127_1691736_3 Protein of unknown function (DUF1559) K02456 - - 0.00000000000001727 83.0
HFD3_k127_1691736_4 beta-propeller repeat - - - 0.0000001862 54.0
HFD3_k127_1699374_0 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 501.0
HFD3_k127_1699374_1 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K07093 - - 0.00000000000000000000000000000000000000000000000000000000000007492 240.0
HFD3_k127_1699374_2 Methyltransferase - - - 0.00000000000000000000000000000000000000007377 160.0
HFD3_k127_1699374_4 Glyco_18 - - - 0.0000008006 63.0
HFD3_k127_1701618_0 Cytochrome c - - - 1.399e-236 772.0
HFD3_k127_1701618_1 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004379 270.0
HFD3_k127_1705005_0 Spore coat protein CotH K01216,K07004 - 3.2.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000003761 275.0
HFD3_k127_1705005_1 Dystroglycan-type cadherin-like domains. - - - 0.00000000000000246 91.0
HFD3_k127_1705005_2 Spore coat protein CotH K07093 - - 0.000000000001428 81.0
HFD3_k127_171184_0 SMART Elongator protein 3 MiaB NifB K06139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 461.0
HFD3_k127_171184_1 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007604 407.0
HFD3_k127_171184_2 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007133 367.0
HFD3_k127_171184_3 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009249 337.0
HFD3_k127_171184_4 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000006468 210.0
HFD3_k127_171184_5 COG3119 Arylsulfatase A and related enzymes - - - 0.000000000006335 66.0
HFD3_k127_1743216_0 beta-glucosidase activity K05350 - 3.2.1.21 0.000000000001845 80.0
HFD3_k127_1743216_1 cellulose binding - - - 0.00000000009323 74.0
HFD3_k127_1751781_0 Concanavalin A-like lectin/glucanases superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 441.0
HFD3_k127_1751781_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005462 441.0
HFD3_k127_1751781_2 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 359.0
HFD3_k127_1751781_3 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000001152 216.0
HFD3_k127_1751781_4 - - - - 0.000000000000000000000000000000000000000000000000000004069 200.0
HFD3_k127_1751781_5 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000003075 131.0
HFD3_k127_1751781_6 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000002889 93.0
HFD3_k127_175229_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 1.306e-273 855.0
HFD3_k127_175229_1 cytochrome C peroxidase - - - 8.369e-195 636.0
HFD3_k127_1767627_0 Belongs to the aldehyde dehydrogenase family K00128,K00130,K00135,K00138,K00146 - 1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.39,1.2.1.79,1.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003883 467.0
HFD3_k127_1767627_1 PFAM Prenyltransferase squalene oxidase K06045 - 4.2.1.129,5.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 411.0
HFD3_k127_1767627_2 polyketide cyclase - - - 0.000000000000000000000000000000000004431 140.0
HFD3_k127_1767627_3 - - - - 0.0000000000000000000000002508 119.0
HFD3_k127_1767627_4 Transglutaminase-like superfamily - - - 0.00000000000000000000002748 113.0
HFD3_k127_1767627_5 Tetratricopeptide repeat - - - 0.00000000000000002596 95.0
HFD3_k127_1777774_0 CARDB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 410.0
HFD3_k127_1783595_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007591 495.0
HFD3_k127_1783595_1 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004351 483.0
HFD3_k127_1783595_2 PFAM AMP-dependent synthetase and ligase K01897,K18661 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 337.0
HFD3_k127_1783595_3 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001984 245.0
HFD3_k127_1783595_4 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000075 227.0
HFD3_k127_1783595_5 Phosphodiester glycosidase - - - 0.000000000000000000000000000000000000000000036 177.0
HFD3_k127_1783595_6 Acetyltransferase (GNAT) domain K03825 - - 0.0000000000000000000000000000000000000000002788 164.0
HFD3_k127_1783595_7 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.000000000000000000000000000000000000000001208 166.0
HFD3_k127_1783595_8 Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.00000000000000000000000001189 117.0
HFD3_k127_1800262_0 Cytochrome c, class I - - - 0.0 1189.0
HFD3_k127_1800262_1 Protein of unknown function (DUF1501) - - - 9.182e-232 726.0
HFD3_k127_1800262_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004075 286.0
HFD3_k127_1800262_3 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.00000004378 56.0
HFD3_k127_1813606_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 7.54e-266 835.0
HFD3_k127_1813606_1 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000571 558.0
HFD3_k127_1813606_2 UPF0365 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005292 433.0
HFD3_k127_1813606_3 PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 413.0
HFD3_k127_1813606_4 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 364.0
HFD3_k127_1813606_5 Membrane-bound serine protease (ClpP class) K07403 - - 0.000000000000000000002347 100.0
HFD3_k127_1813606_6 Domain of unknown function (DUF362) - - - 0.00000000000000008534 93.0
HFD3_k127_1813606_7 Transmembrane and TPR repeat-containing protein 4 - - - 0.000000000001482 81.0
HFD3_k127_1813606_8 membrane protein, required for colicin V production K03558 - - 0.0009869 49.0
HFD3_k127_1817830_0 Glutathionylspermidine synthase preATP-grasp - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003614 271.0
HFD3_k127_1817830_1 Domain of unknown function (DUF1732) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002461 267.0
HFD3_k127_1817830_2 Glycosyl hydrolase family 92 - - - 0.0000000000000000000001279 114.0
HFD3_k127_1817830_3 Domain of Unknown Function (DUF350) - - - 0.000000005269 61.0
HFD3_k127_1831768_0 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000001109 188.0
HFD3_k127_1831768_1 quinone binding K01829,K03673,K03805,K03981,K12228 GO:0003674,GO:0003756,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0015035,GO:0015036,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0055114,GO:0140096 5.3.4.1 0.000000000000000000000000000000003027 145.0
HFD3_k127_183985_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.657e-282 880.0
HFD3_k127_183985_1 Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007254 441.0
HFD3_k127_183985_2 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 300.0
HFD3_k127_183985_3 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000001683 229.0
HFD3_k127_183985_4 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000007218 203.0
HFD3_k127_1851080_0 xylose isomerase activity K01805 - 5.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007454 376.0
HFD3_k127_1851080_1 ABC-2 family transporter protein - - - 0.000000000584 70.0
HFD3_k127_1851080_2 ABC-2 family transporter protein - - - 0.0001364 55.0
HFD3_k127_1868036_0 CotH kinase protein - - - 0.0 1169.0
HFD3_k127_1868036_1 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000004587 168.0
HFD3_k127_1872583_0 Phosphoesterase family - - - 0.0 1086.0
HFD3_k127_1872583_1 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000000000000006767 160.0
HFD3_k127_1872583_2 GAF domain - - - 0.00000000000000000000000007254 110.0
HFD3_k127_1872583_3 Tetratricopeptide repeat - - - 0.0000000000000000000000385 102.0
HFD3_k127_1874499_0 Tryptophan halogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007177 589.0
HFD3_k127_1874499_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 573.0
HFD3_k127_1874499_2 PFAM Pyrrolo-quinoline quinone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007092 413.0
HFD3_k127_1874499_3 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000009382 256.0
HFD3_k127_1874499_4 Integral membrane protein TerC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002122 242.0
HFD3_k127_1874499_5 chorismate lyase activity - - - 0.00000000000000000000000000000000005282 143.0
HFD3_k127_1874499_7 Large extracellular alpha-helical protein K13735,K20276 - - 0.00000000000002272 87.0
HFD3_k127_1880055_0 Protein of unknown function (DUF1549) - - - 1.386e-290 928.0
HFD3_k127_1880055_1 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009034 404.0
HFD3_k127_1880055_2 WD domain, G-beta repeat - - - 0.000000000000000000000000000003886 125.0
HFD3_k127_1889248_0 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 601.0
HFD3_k127_1889248_1 Alcohol dehydrogenase GroES-like domain K00060 - 1.1.1.103 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007685 404.0
HFD3_k127_1889248_2 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000003311 201.0
HFD3_k127_1889248_3 Bacterial protein of unknown function (DUF883) - - - 0.000000002297 63.0
HFD3_k127_1889248_4 Protein of unknown function (DUF2892) - - - 0.00009437 51.0
HFD3_k127_190685_0 Protein of unknown function (DUF1549) - - - 4.483e-291 918.0
HFD3_k127_190685_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.925e-264 835.0
HFD3_k127_190685_2 Protein of unknown function (DUF1501) - - - 7.88e-215 685.0
HFD3_k127_190685_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000005271 83.0
HFD3_k127_1910427_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 2.424e-205 668.0
HFD3_k127_1914785_0 PFAM Prenyltransferase squalene oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007438 446.0
HFD3_k127_1914785_1 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001104 246.0
HFD3_k127_1914785_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585,K18306 - - 0.0000000001746 66.0
HFD3_k127_1917417_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005828 364.0
HFD3_k127_1917417_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 307.0
HFD3_k127_1917417_2 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000001359 136.0
HFD3_k127_1917417_3 - - - - 0.0000000000000000000000002883 117.0
HFD3_k127_1921240_0 Glycerol-3-phosphate dehydrogenase K00057 GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0046167,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901576 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001593 295.0
HFD3_k127_1921240_1 TIGRFAM phosphoserine phosphatase homoserine phosphotransferase bifunctional protein K02203 - 2.7.1.39,3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000006874 251.0
HFD3_k127_1921240_2 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000002501 180.0
HFD3_k127_1921240_3 C4-type zinc ribbon domain K07164 - - 0.000000000000000000006397 98.0
HFD3_k127_1921240_4 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000568 87.0
HFD3_k127_1921240_5 Prokaryotic N-terminal methylation motif - - - 0.00000000000007842 83.0
HFD3_k127_1954023_0 Protein of unknown function (DUF1549) - - - 1.308e-265 843.0
HFD3_k127_1954023_1 Protein of unknown function (DUF1501) - - - 1.083e-222 700.0
HFD3_k127_1954023_2 PQQ-like domain - - - 0.000000000000000000000000000000000000003432 153.0
HFD3_k127_197796_0 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 389.0
HFD3_k127_197796_1 pfkB family carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 337.0
HFD3_k127_197796_2 ParB-like nuclease domain K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003345 272.0
HFD3_k127_197796_3 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000103 235.0
HFD3_k127_197796_4 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000003683 181.0
HFD3_k127_197796_5 radical SAM domain protein - - - 0.000000000000001569 78.0
HFD3_k127_1990429_0 TIGRFAM amino acid adenylation domain - - - 0.0 1121.0
HFD3_k127_1990429_1 non-ribosomal peptide synthetase - - - 1.721e-236 761.0
HFD3_k127_2014133_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 4.477e-283 883.0
HFD3_k127_2014133_1 FIST C domain - GO:0008150,GO:0040007 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009326 340.0
HFD3_k127_2014133_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K03737 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 293.0
HFD3_k127_2014133_3 Domain of unknown function (DUF4956) - - - 0.000000000000000000000003413 111.0
HFD3_k127_2014133_4 Biotin-lipoyl like K03543 - - 0.0001312 53.0
HFD3_k127_201902_0 Type II secretion system (T2SS), protein K - - - 0.0000000000000000000000000000000000001807 155.0
HFD3_k127_201902_1 Bacterial type II/III secretion system short domain - - - 0.000004593 55.0
HFD3_k127_201902_2 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.0000878 55.0
HFD3_k127_2032557_0 PHP domain protein - - - 0.00000000000000000000000000000000000000001082 166.0
HFD3_k127_2032557_2 PFAM glycosyl transferase family 2 - - - 0.000000000000000000000000001183 119.0
HFD3_k127_2038203_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 566.0
HFD3_k127_2038203_1 TM2 domain - - - 0.000000000000000000000000000000000000000000000000000000000001853 221.0
HFD3_k127_2038203_2 HupE / UreJ protein - - - 0.000000000000000000000000000000000000000000000000000000007678 202.0
HFD3_k127_2038203_3 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.00000000000000000000000000000000000000001197 157.0
HFD3_k127_2038203_4 Glycosyl hydrolases family 2, TIM barrel domain - - - 0.00000000008325 73.0
HFD3_k127_2038203_5 hyperosmotic response K04065 - - 0.0000005633 57.0
HFD3_k127_2047922_0 Glycosyl hydrolase-like 10 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 532.0
HFD3_k127_2047922_1 response to antibiotic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 524.0
HFD3_k127_2047922_2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007662 418.0
HFD3_k127_2047922_3 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 310.0
HFD3_k127_2047922_4 Periplasmic binding protein LacI transcriptional regulator K02529 - - 0.00000000000000000000000000000000000000000000000000000000006648 218.0
HFD3_k127_2047922_5 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000001197 211.0
HFD3_k127_2047922_6 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000006768 192.0
HFD3_k127_2047922_7 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000004691 151.0
HFD3_k127_2047922_8 Caspase domain K07369 - - 0.000000004388 72.0
HFD3_k127_2056686_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 398.0
HFD3_k127_2056686_1 ResB-like family - - - 0.000000000000000000000000000000000000000000000000000000000001957 220.0
HFD3_k127_2056686_2 - - - - 0.0000000000000000000000000000000000000007714 163.0
HFD3_k127_2116380_0 COGs COG1020 Non-ribosomal peptide synthetase modules and related protein - - - 0.0 1042.0
HFD3_k127_2116380_1 Pyruvate phosphate dikinase K01007,K22424 - 2.7.3.13,2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009324 549.0
HFD3_k127_2116380_2 Catalyzes the synthesis of activated sulfate - - - 0.0000000000000000000000000000000000000006101 155.0
HFD3_k127_2116380_3 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0004082 44.0
HFD3_k127_2129729_0 Phosphoglycerate kinase K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 460.0
HFD3_k127_2129729_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000001047 117.0
HFD3_k127_213212_0 DNA topoisomerase (ATP-hydrolyzing) K02470,K02622 - 5.99.1.3 1.063e-237 749.0
HFD3_k127_213212_1 Uncharacterised protein family (UPF0261) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 587.0
HFD3_k127_213212_2 Arylsulfatase a K01133 - 3.1.6.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 539.0
HFD3_k127_213212_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009732 292.0
HFD3_k127_213212_4 Redoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006855 245.0
HFD3_k127_213212_5 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000001616 224.0
HFD3_k127_213212_6 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000009821 183.0
HFD3_k127_213212_7 Concanavalin A-like lectin/glucanases superfamily - - - 0.000000000000000000000000001963 120.0
HFD3_k127_213212_8 Tetratricopeptide repeat - - - 0.000000000000000000000000004534 128.0
HFD3_k127_213212_9 - - - - 0.00000000000000000000000001003 116.0
HFD3_k127_2133396_0 Hep Hag repeat protein - - - 0.0000000000000000000000000000000000000207 166.0
HFD3_k127_2133396_1 S-layer domain-containing protein - - - 0.000000000000000000000000000009583 138.0
HFD3_k127_2133396_2 Glucose / Sorbosone dehydrogenase - - - 0.000000000009169 79.0
HFD3_k127_2133638_0 Planctomycete cytochrome C - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 541.0
HFD3_k127_2133638_1 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004426 452.0
HFD3_k127_216088_0 amine dehydrogenase activity - - - 2.372e-244 803.0
HFD3_k127_216088_1 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009209 548.0
HFD3_k127_216088_2 Y_Y_Y domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 473.0
HFD3_k127_216088_3 PFAM regulatory protein LuxR - - - 0.00000000000000000000000000000000000000000000000000000000000000003265 230.0
HFD3_k127_216088_4 PFAM Formylglycine-generating sulfatase enzyme K20276 - - 0.00000000000000000000000000000000000000000000000000000000002961 224.0
HFD3_k127_216088_5 Carbohydrate family 9 binding domain-like - - - 0.000000000000000000000000000007545 132.0
HFD3_k127_216088_6 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000000001982 115.0
HFD3_k127_216088_7 Hep Hag repeat protein - - - 0.000000000000000003279 98.0
HFD3_k127_216088_8 Titin Z K12567 GO:0000070,GO:0000228,GO:0000278,GO:0000280,GO:0000793,GO:0000794,GO:0000819,GO:0001701,GO:0001756,GO:0001932,GO:0002020,GO:0002576,GO:0002791,GO:0002793,GO:0003002,GO:0003007,GO:0003008,GO:0003012,GO:0003013,GO:0003015,GO:0003300,GO:0003674,GO:0003779,GO:0003824,GO:0004672,GO:0004674,GO:0004713,GO:0005198,GO:0005200,GO:0005488,GO:0005509,GO:0005515,GO:0005516,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005829,GO:0005856,GO:0005859,GO:0005865,GO:0006323,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006928,GO:0006936,GO:0006941,GO:0006996,GO:0007010,GO:0007015,GO:0007049,GO:0007059,GO:0007076,GO:0007154,GO:0007165,GO:0007275,GO:0007389,GO:0007399,GO:0007417,GO:0007420,GO:0007507,GO:0007512,GO:0007517,GO:0008015,GO:0008092,GO:0008150,GO:0008152,GO:0008307,GO:0009581,GO:0009582,GO:0009605,GO:0009612,GO:0009628,GO:0009653,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009893,GO:0009952,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010604,GO:0010628,GO:0010737,GO:0010927,GO:0014706,GO:0014866,GO:0014896,GO:0014897,GO:0015629,GO:0016043,GO:0016192,GO:0016301,GO:0016310,GO:0016459,GO:0016460,GO:0016740,GO:0016772,GO:0016773,GO:0018108,GO:0018193,GO:0018212,GO:0019220,GO:0019222,GO:0019538,GO:0019899,GO:0019900,GO:0019901,GO:0021591,GO:0022402,GO:0022607,GO:0023052,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030048,GO:0030049,GO:0030154,GO:0030239,GO:0030240,GO:0030241,GO:0030261,GO:0030506,GO:0031032,GO:0031033,GO:0031034,GO:0031323,GO:0031399,GO:0031430,GO:0031433,GO:0031672,GO:0031674,GO:0031974,GO:0031981,GO:0032268,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0032940,GO:0032989,GO:0032991,GO:0033058,GO:0033275,GO:0034622,GO:0035051,GO:0035265,GO:0035282,GO:0035556,GO:0035994,GO:0035995,GO:0036211,GO:0036379,GO:0040007,GO:0040011,GO:0042221,GO:0042325,GO:0042692,GO:0042802,GO:0042805,GO:0043009,GO:0043056,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043292,GO:0043412,GO:0043549,GO:0043621,GO:0043933,GO:0044057,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044449,GO:0044464,GO:0044877,GO:0045055,GO:0045214,GO:0045859,GO:0046872,GO:0046903,GO:0048285,GO:0048468,GO:0048513,GO:0048518,GO:0048522,GO:0048589,GO:0048644,GO:0048646,GO:0048729,GO:0048731,GO:0048738,GO:0048739,GO:0048747,GO:0048769,GO:0048856,GO:0048869,GO:0050708,GO:0050714,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0050982,GO:0051015,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051146,GO:0051171,GO:0051174,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051246,GO:0051276,GO:0051338,GO:0051371,GO:0051393,GO:0051592,GO:0051606,GO:0051716,GO:0055001,GO:0055002,GO:0055003,GO:0055006,GO:0055007,GO:0055008,GO:0055013,GO:0060047,GO:0060048,GO:0060255,GO:0060322,GO:0060415,GO:0060419,GO:0060429,GO:0060537,GO:0061053,GO:0061061,GO:0065003,GO:0065007,GO:0065009,GO:0070013,GO:0070201,GO:0070252,GO:0070925,GO:0071103,GO:0071688,GO:0071704,GO:0071840,GO:0072359,GO:0080090,GO:0090087,GO:0090257,GO:0097435,GO:0097493,GO:0098813,GO:0099080,GO:0099081,GO:0099512,GO:0140014,GO:0140096,GO:1901077,GO:1901564,GO:1901897,GO:1903047,GO:1903530,GO:1903532,GO:1904951 2.7.11.1 0.00000000162 72.0
HFD3_k127_216088_9 peptidase M4 thermolysin K01399,K08604 GO:0005575,GO:0005576 3.4.24.25,3.4.24.26 0.00000002535 68.0
HFD3_k127_2162658_0 Proline dehydrogenase K13821 - 1.2.1.88,1.5.5.2 1.285e-226 716.0
HFD3_k127_2162658_1 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 349.0
HFD3_k127_2162658_2 cell redox homeostasis K00382,K00520 - 1.16.1.1,1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 299.0
HFD3_k127_2162658_3 Belongs to the GTP cyclohydrolase I type 2 NIF3 family K22391 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0050896 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004441 297.0
HFD3_k127_2162658_4 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000003507 209.0
HFD3_k127_2162658_5 histidine kinase HAMP region domain protein K07710 - 2.7.13.3 0.0000000000000000000000000000000000000000000003463 181.0
HFD3_k127_2162658_6 - - - - 0.0000000000000000000000000000000000005004 147.0
HFD3_k127_2184483_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007365 517.0
HFD3_k127_2184483_1 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005359 399.0
HFD3_k127_2184483_2 Malate/L-lactate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 405.0
HFD3_k127_2184483_3 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 379.0
HFD3_k127_2184483_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 325.0
HFD3_k127_2184483_5 Zn-dependent protease - - - 0.000000000000000000000000000000000000000032 166.0
HFD3_k127_2184483_6 Forkhead associated domain - - - 0.00006048 55.0
HFD3_k127_2187179_0 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 495.0
HFD3_k127_2187179_1 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005471 403.0
HFD3_k127_2187179_2 lipoprotein transporter activity K02003,K09814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006492 314.0
HFD3_k127_2187179_3 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000105 261.0
HFD3_k127_2187179_4 protein histidine kinase activity K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000001095 249.0
HFD3_k127_2187179_5 - - - - 0.00000000000000000000000000000000003301 157.0
HFD3_k127_2190580_0 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005242 327.0
HFD3_k127_2190580_1 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000000000000003011 215.0
HFD3_k127_2190580_2 lipolytic protein G-D-S-L family K00612 - - 0.0000000000000000000000000000000000000001066 163.0
HFD3_k127_2190580_3 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000223 117.0
HFD3_k127_2190580_5 Lissencephaly type-1-like homology motif K16794 GO:0000003,GO:0000132,GO:0000226,GO:0000278,GO:0000775,GO:0000776,GO:0000922,GO:0003006,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005815,GO:0005816,GO:0005819,GO:0005856,GO:0005874,GO:0005875,GO:0005881,GO:0005938,GO:0006810,GO:0006928,GO:0006996,GO:0007010,GO:0007017,GO:0007018,GO:0007049,GO:0007097,GO:0007163,GO:0008017,GO:0008092,GO:0008150,GO:0009653,GO:0009987,GO:0010970,GO:0015630,GO:0015631,GO:0016043,GO:0019953,GO:0019954,GO:0022402,GO:0022414,GO:0030010,GO:0030154,GO:0030435,GO:0030436,GO:0030473,GO:0030705,GO:0031023,GO:0032092,GO:0032502,GO:0032781,GO:0032991,GO:0034293,GO:0040001,GO:0043085,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043393,GO:0043462,GO:0043934,GO:0043935,GO:0044093,GO:0044422,GO:0044424,GO:0044427,GO:0044430,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044877,GO:0046907,GO:0047496,GO:0048315,GO:0048468,GO:0048646,GO:0048856,GO:0048869,GO:0050790,GO:0051010,GO:0051098,GO:0051099,GO:0051179,GO:0051234,GO:0051293,GO:0051294,GO:0051321,GO:0051336,GO:0051345,GO:0051640,GO:0051641,GO:0051647,GO:0051648,GO:0051649,GO:0051650,GO:0051653,GO:0051656,GO:0051704,GO:0061794,GO:0065007,GO:0065009,GO:0070840,GO:0071840,GO:0071944,GO:0072384,GO:0098687,GO:0099080,GO:0099081,GO:0099111,GO:0099512,GO:0099513,GO:0099518,GO:0099568,GO:1902850,GO:1903031,GO:1903033,GO:1903046,GO:1903047,GO:1904526,GO:1904528,GO:2000574,GO:2000576,GO:2000580,GO:2000582 - 0.0001783 55.0
HFD3_k127_2198396_0 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 424.0
HFD3_k127_2198396_1 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 340.0
HFD3_k127_2198396_2 Cobalamin adenosyltransferase - - - 0.000000000000000000000000000000000000000000000000000001387 197.0
HFD3_k127_2198396_3 signal sequence binding K07152 - - 0.00000000000000000000000000000000000000000000000000005668 195.0
HFD3_k127_2198396_4 Multicopper oxidase - - - 0.0000000006125 60.0
HFD3_k127_2202086_0 Glycosyl Hydrolase Family 88 K18581 - 3.2.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000734 356.0
HFD3_k127_2202086_1 glucosamine-6-phosphate deaminase activity K01057,K02564 - 3.1.1.31,3.5.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 336.0
HFD3_k127_2202086_2 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008384 318.0
HFD3_k127_2202086_3 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 307.0
HFD3_k127_2202086_4 Universal stress protein family - - - 0.00004835 51.0
HFD3_k127_2221526_0 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 424.0
HFD3_k127_2221526_1 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 321.0
HFD3_k127_2221526_2 Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000002799 193.0
HFD3_k127_2221526_3 - - - - 0.0000000000000000000008901 98.0
HFD3_k127_2221526_4 CotH kinase protein - - - 0.0000361 56.0
HFD3_k127_2221635_0 PFAM ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 422.0
HFD3_k127_2221635_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004773 332.0
HFD3_k127_2221635_2 response regulator K07670 - - 0.00000000000000000001342 99.0
HFD3_k127_2221635_3 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.0000000000008375 69.0
HFD3_k127_2226706_0 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 9.488e-244 803.0
HFD3_k127_2235072_0 PFAM glycoside hydrolase family 39 K01198 - 3.2.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 377.0
HFD3_k127_2235072_1 PFAM SMP-30 Gluconolaconase K01179,K01181,K01218,K02014 - 3.2.1.4,3.2.1.78,3.2.1.8 0.00000000000000000000000000000000000000000000000000000000000001028 239.0
HFD3_k127_2247654_0 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006663 319.0
HFD3_k127_2247654_1 von Willebrand factor type A domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009135 287.0
HFD3_k127_2247654_2 oxidoreductase activity K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000006279 234.0
HFD3_k127_2247654_3 Associated with various cellular activities K03924 - - 0.00000000000000000000000000000000001348 137.0
HFD3_k127_2247654_4 - - - - 0.0000000000000000000000000000008466 135.0
HFD3_k127_2247654_5 - - - - 0.00000000000001251 85.0
HFD3_k127_2247654_6 - - - - 0.00000002673 66.0
HFD3_k127_2248073_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003516 456.0
HFD3_k127_2248073_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 424.0
HFD3_k127_2248073_2 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008633 420.0
HFD3_k127_2248073_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 421.0
HFD3_k127_2248073_4 PFAM ABC transporter related K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 330.0
HFD3_k127_2248073_5 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 318.0
HFD3_k127_2248073_6 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 301.0
HFD3_k127_2248073_7 response to antibiotic - - - 0.0000000000000000000000000000000000000000000000000003603 195.0
HFD3_k127_2258453_0 Protein of unknown function (DUF1549) - - - 2.714e-282 889.0
HFD3_k127_2258453_1 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006387 553.0
HFD3_k127_2263537_0 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001039 280.0
HFD3_k127_2263537_1 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000000000000008447 169.0
HFD3_k127_2264485_0 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 520.0
HFD3_k127_2264485_1 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002899 263.0
HFD3_k127_2264485_3 Glycosyl transferase, family 2 K16648,K20444 - - 0.00000000000000000000000000000000000007786 156.0
HFD3_k127_2265677_0 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000002985 235.0
HFD3_k127_2265677_1 Thiopurine S-methyltransferase (TPMT) - - - 0.000000000000000000000000000000000000000000131 167.0
HFD3_k127_2265677_2 response to antibiotic - - - 0.00000000000000000000000000000000000000006905 171.0
HFD3_k127_2265677_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000872 132.0
HFD3_k127_2273153_0 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 417.0
HFD3_k127_2273153_1 AAA-like domain - - - 0.0000000000000000000000000000000000000008118 170.0
HFD3_k127_2273153_2 beta-galactosidase activity - - - 0.000000000000000003673 100.0
HFD3_k127_2273153_3 HlyD membrane-fusion protein of T1SS K01993 - - 0.000000003931 68.0
HFD3_k127_2273153_4 Bacterial protein of unknown function (DUF885) - - - 0.00000001307 67.0
HFD3_k127_2312318_0 ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009433 399.0
HFD3_k127_2312318_1 Aminotransferase class-V K04487 GO:0003674,GO:0003824,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0016740,GO:0016782,GO:0016783,GO:0022607,GO:0031071,GO:0031163,GO:0040007,GO:0044085,GO:0044237,GO:0051186,GO:0071840 2.8.1.7 0.0007647 44.0
HFD3_k127_2314090_0 PFAM YD repeat-containing protein - - - 1.002e-224 768.0
HFD3_k127_2336004_0 PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 8.508e-232 765.0
HFD3_k127_2336004_1 PhoD-like phosphatase K01113,K07093 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006661 361.0
HFD3_k127_2343946_0 B12 binding domain - - - 5.186e-199 631.0
HFD3_k127_2343946_1 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 451.0
HFD3_k127_2343946_2 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000002003 244.0
HFD3_k127_2374305_0 iron ion homeostasis - - - 1.489e-219 716.0
HFD3_k127_2374305_1 COG3119 Arylsulfatase A and related enzymes K01130 - 3.1.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 610.0
HFD3_k127_2374305_2 Protein kinase domain - - - 0.000000000000000000000000000000000000005788 167.0
HFD3_k127_2378493_0 pyrroloquinoline quinone binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 589.0
HFD3_k127_2378493_1 metalloendopeptidase activity K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009144 490.0
HFD3_k127_2378493_2 Spermine/spermidine synthase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000164 251.0
HFD3_k127_2393787_0 Large extracellular alpha-helical protein K06894 - - 0.0 2314.0
HFD3_k127_2393787_1 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 444.0
HFD3_k127_2393787_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 413.0
HFD3_k127_2393787_3 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 346.0
HFD3_k127_2393787_4 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000003349 143.0
HFD3_k127_2393787_5 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000003344 89.0
HFD3_k127_2431550_0 Pkd domain containing protein - - - 0.00000000000000000000000000000000000000000000000004487 207.0
HFD3_k127_2431550_1 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000001184 139.0
HFD3_k127_2431550_2 Belongs to the peptidase S8 family - - - 0.000000000001037 83.0
HFD3_k127_2445451_0 cytochrome C peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009588 437.0
HFD3_k127_2445451_1 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005066 302.0
HFD3_k127_2445451_2 Phosphate acetyl/butaryl transferase K00625 - 2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000004801 248.0
HFD3_k127_2454087_0 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000002793 235.0
HFD3_k127_2454087_1 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000006844 206.0
HFD3_k127_2454087_2 thioesterase K07107,K12500 - - 0.0000000000000000000000000000000000000000000000002904 179.0
HFD3_k127_2454087_3 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000009621 151.0
HFD3_k127_2460361_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1184.0
HFD3_k127_2460361_1 Bacterial protein of unknown function (DUF883) - - - 0.0000001102 58.0
HFD3_k127_2460361_2 CoA binding domain K09181 - - 0.0004335 46.0
HFD3_k127_2465664_0 Y_Y_Y domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003499 451.0
HFD3_k127_2465664_1 AIR synthase related protein, N-terminal domain K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007427 394.0
HFD3_k127_2465664_2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 293.0
HFD3_k127_2465664_3 PFAM regulatory protein LuxR - - - 0.0000000000000000000000000000000000000000000000000000000008296 208.0
HFD3_k127_2465664_4 Domain of unknown function (DUF4404) - - - 0.000000000000000000000000000000002343 132.0
HFD3_k127_2473816_0 DNA-directed 5'-3' RNA polymerase activity K03043,K13797 GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.0 1453.0
HFD3_k127_2473816_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 2.132e-293 908.0
HFD3_k127_2473816_2 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 286.0
HFD3_k127_2473816_3 Participates in transcription elongation, termination and antitermination K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000009993 226.0
HFD3_k127_2473816_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000000000000000008083 207.0
HFD3_k127_2473816_5 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000000000009352 168.0
HFD3_k127_2473816_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000001766 133.0
HFD3_k127_2473816_7 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.0000002164 56.0
HFD3_k127_2475620_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 520.0
HFD3_k127_2475620_1 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005784 300.0
HFD3_k127_2475620_2 Protein conserved in bacteria K20920 - - 0.0000000002719 71.0
HFD3_k127_2479236_0 chitinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000495 394.0
HFD3_k127_2479236_1 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000002208 169.0
HFD3_k127_2479236_2 Membrane-bound dehydrogenase domain - - - 0.000000000002534 68.0
HFD3_k127_2492192_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005097 403.0
HFD3_k127_2492192_1 Polysaccharide biosynthesis protein K08679 - 5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 354.0
HFD3_k127_2492192_2 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000172 252.0
HFD3_k127_2492192_3 Beta propeller domain - - - 0.0000000000000000000000000000000000000000007317 182.0
HFD3_k127_2492192_4 YjbR - - - 0.000000000000000000000000000001002 124.0
HFD3_k127_2493318_0 thiolester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 451.0
HFD3_k127_2493318_1 PFAM type II secretion system K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000386 422.0
HFD3_k127_2493318_2 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001182 287.0
HFD3_k127_2493318_4 phosphorelay signal transduction system K13599 - - 0.000000000000000000000000000000114 131.0
HFD3_k127_2493318_6 PFAM L,D-transpeptidase catalytic domain - - - 0.0005168 51.0
HFD3_k127_249495_0 cephalosporin-C deacetylase activity - - - 8.458e-258 815.0
HFD3_k127_249495_1 Glycosyl transferase, family 2 - - - 3.296e-215 696.0
HFD3_k127_249495_10 Pectic acid lyase - - - 0.000001012 62.0
HFD3_k127_249495_2 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003922 612.0
HFD3_k127_249495_3 Bacterial Ig-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 451.0
HFD3_k127_249495_4 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 426.0
HFD3_k127_249495_5 N-acetylmuramoyl-L-alanine amidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004522 388.0
HFD3_k127_249495_6 Myo-inositol oxygenase K00469 - 1.13.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 362.0
HFD3_k127_249495_7 iron ion binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007464 285.0
HFD3_k127_249495_8 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.0000000000000000000000000000000000003212 141.0
HFD3_k127_249495_9 PFAM outer membrane efflux protein - - - 0.000000000000000000000000000000000213 154.0
HFD3_k127_2512802_0 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 561.0
HFD3_k127_2512802_1 homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 523.0
HFD3_k127_2512802_2 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003332 460.0
HFD3_k127_2512802_3 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002574 275.0
HFD3_k127_2512802_4 Protein of unknown function (DUF1549) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006276 289.0
HFD3_k127_2512802_5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000001924 111.0
HFD3_k127_2512802_6 3-isopropylmalate dehydratase, small subunit K01704 - 4.2.1.33,4.2.1.35 0.0000000000001373 71.0
HFD3_k127_2526170_0 PFAM Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005541 521.0
HFD3_k127_2526170_1 pyrroloquinoline quinone binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008613 320.0
HFD3_k127_2526170_2 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004516 274.0
HFD3_k127_2526170_3 Cytochrome c - - - 0.00000000000000000000000000000003875 135.0
HFD3_k127_2526170_4 Phosphodiester glycosidase - - - 0.0000000000000000000000000001191 134.0
HFD3_k127_255530_0 Aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006284 604.0
HFD3_k127_255530_1 glutaminyl-tRNA synthetase K01886 - 6.1.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009988 598.0
HFD3_k127_255530_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 595.0
HFD3_k127_255530_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009667 547.0
HFD3_k127_255530_4 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000001569 92.0
HFD3_k127_2555314_0 glycosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004321 384.0
HFD3_k127_2555314_1 NmrA-like family K00091 - 1.1.1.219 0.0000000000000006372 78.0
HFD3_k127_2561096_0 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 479.0
HFD3_k127_2561096_1 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 408.0
HFD3_k127_2561096_2 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000000000000000000000009868 240.0
HFD3_k127_2561096_3 Pectate lyase superfamily protein - - - 0.000000000000000000000000000000000000000000009807 173.0
HFD3_k127_25905_0 alpha-L-rhamnosidase - - - 0.000000000000000000000000000000000000000000000000000001215 203.0
HFD3_k127_25905_1 Aldo/keto reductase family - - - 0.0000000000000009592 89.0
HFD3_k127_25905_2 Cytochrome c3 - - - 0.0009007 49.0
HFD3_k127_2601767_0 FGGY family of carbohydrate kinases, C-terminal domain K00854 - 2.7.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 570.0
HFD3_k127_2601767_1 DegT/DnrJ/EryC1/StrS aminotransferase family K04127 - 5.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 514.0
HFD3_k127_2601767_2 Biotin and Thiamin Synthesis associated domain K03150 - 4.1.99.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007205 498.0
HFD3_k127_2601767_3 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 467.0
HFD3_k127_2601767_4 Protein of unknown function, DUF255 - - - 0.000000000000000000000004696 108.0
HFD3_k127_2610580_0 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 582.0
HFD3_k127_2610580_1 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006511 563.0
HFD3_k127_2610580_2 Amino acid kinase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 505.0
HFD3_k127_2610580_3 acid phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 340.0
HFD3_k127_2610580_4 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000006733 167.0
HFD3_k127_2610580_5 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000001066 166.0
HFD3_k127_2610580_6 PFAM Sulfate transporter antisigma-factor antagonist STAS - - - 0.0000000000000000000000027 109.0
HFD3_k127_2610580_7 Cysteine-rich CPXCG - - - 0.000000002251 59.0
HFD3_k127_2610580_8 Transmembrane proteins 14C - - - 0.000007137 53.0
HFD3_k127_2613351_0 Glycosyl hydrolase family 32 K01193,K03332 - 3.2.1.26,3.2.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 351.0
HFD3_k127_2613351_1 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.7 0.000000000000000000000000000000000000000000000000000003724 196.0
HFD3_k127_2613351_2 CotH kinase protein - - - 0.0000000000000000000000000000000000000000000000000004525 199.0
HFD3_k127_2613351_3 Belongs to the glycosyl hydrolase 32 family K01212,K03332 - 3.2.1.65,3.2.1.80 0.0000000000000000000000000000000000000009523 168.0
HFD3_k127_2613351_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000311 101.0
HFD3_k127_2620443_0 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 6.158e-214 673.0
HFD3_k127_2620443_1 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 497.0
HFD3_k127_2620443_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001068 295.0
HFD3_k127_2620443_3 COG0367 Asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007346 284.0
HFD3_k127_2620443_4 Aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000004023 239.0
HFD3_k127_2620443_5 coenzyme F390 K01912 - 6.2.1.30 0.0000000000000000000000000000000000000001363 169.0
HFD3_k127_2620443_6 PHP-associated - - - 0.0000000000000000001313 99.0
HFD3_k127_2622106_0 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004333 427.0
HFD3_k127_2622106_1 FecR protein - - - 0.00002377 55.0
HFD3_k127_2622106_2 BlaR1 peptidase M56 - - - 0.00004248 56.0
HFD3_k127_2622106_3 Glycosyl hydrolase family 20, catalytic domain - - - 0.0006818 52.0
HFD3_k127_2639747_0 amine dehydrogenase activity - - - 1.118e-236 756.0
HFD3_k127_2639747_1 alcohol dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003092 443.0
HFD3_k127_2639747_2 MacB-like periplasmic core domain K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007532 322.0
HFD3_k127_2639747_3 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005165 260.0
HFD3_k127_2639747_4 Peptidase M48 K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000007023 183.0
HFD3_k127_2639747_5 PFAM Class I peptide chain release factor - - - 0.0000000000000000000000000000911 120.0
HFD3_k127_2642849_0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 550.0
HFD3_k127_2642849_1 SMART metal-dependent phosphohydrolase HD region K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006715 453.0
HFD3_k127_2642849_2 Two component transcriptional regulator, LuxR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009937 262.0
HFD3_k127_2642849_3 Histidine kinase K07675,K09684 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000001982 239.0
HFD3_k127_2642849_4 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000001804 232.0
HFD3_k127_2664099_0 L-rhamnose isomerase K01813 GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0008740,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0019321,GO:0019324,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575 5.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 581.0
HFD3_k127_2664099_1 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 325.0
HFD3_k127_2664099_2 endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000001038 139.0
HFD3_k127_2664099_3 NPCBM/NEW2 domain - - - 0.0000000000000000000000000003242 124.0
HFD3_k127_2664099_4 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0002542 54.0
HFD3_k127_2688445_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004021 495.0
HFD3_k127_2688445_1 Histidine kinase K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 356.0
HFD3_k127_2688445_2 Two component transcriptional regulator, winged helix family K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008576 306.0
HFD3_k127_2688445_3 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000002229 231.0
HFD3_k127_2688445_4 Acid phosphatase homologues - - - 0.000000000000000000000000000000000000003786 156.0
HFD3_k127_2688445_5 Peptidase M50 - - - 0.0000000000000000000000000000000002171 140.0
HFD3_k127_2688445_6 Adenylosuccinate lyase C-terminus K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 0.00000000000000008033 84.0
HFD3_k127_269063_0 Concanavalin A-like lectin/glucanases superfamily - - - 0.0 1187.0
HFD3_k127_269063_1 Protein of unknown function (DUF1501) - - - 1.338e-229 720.0
HFD3_k127_269063_2 PFAM Neutral alkaline nonlysosomal ceramidase - - - 1.303e-199 635.0
HFD3_k127_269063_3 COG3119 Arylsulfatase A K01138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 512.0
HFD3_k127_2696455_0 ATP-dependent helicase C-terminal K03579 - 3.6.4.13 2.065e-261 823.0
HFD3_k127_2696455_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000408 148.0
HFD3_k127_2696455_2 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000006916 120.0
HFD3_k127_2696455_3 PFAM Glycosyl transferase family 2 - - - 0.000000000000000006481 96.0
HFD3_k127_2696455_4 COG0500 SAM-dependent methyltransferases - - - 0.00001054 57.0
HFD3_k127_2701659_0 Acyl-CoA reductase (LuxC) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006789 254.0
HFD3_k127_2701659_1 PFAM AMP-dependent synthetase and ligase K00666 - - 0.00000000000000000000000000000000000000000000000000006697 202.0
HFD3_k127_2701659_2 synthase K01737 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0070497,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000738 168.0
HFD3_k127_2701659_3 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000008144 103.0
HFD3_k127_2737810_0 CotH kinase protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009567 579.0
HFD3_k127_2737810_1 PFAM Di-glucose binding within endoplasmic reticulum - - - 0.000000000000000000000000000000001345 151.0
HFD3_k127_2737810_2 Belongs to the glycosyl hydrolase 43 family K22350 - 1.16.3.3 0.00002597 51.0
HFD3_k127_2743763_0 ASPIC UnbV domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 493.0
HFD3_k127_2745903_0 iron-sulfur cluster assembly K07033,K09014 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009536,GO:0009842,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840 - 6.626e-262 814.0
HFD3_k127_2745903_1 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 423.0
HFD3_k127_2745903_2 ABC transporter K09013 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004676 375.0
HFD3_k127_2745903_3 Ferric uptake regulator family K09825 - - 0.00000000000000000000000000000000006157 138.0
HFD3_k127_2745903_4 Uncharacterized protein family (UPF0051) K09015 - - 0.000000000000000000000001817 109.0
HFD3_k127_2753926_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 8.273e-211 679.0
HFD3_k127_2753926_1 Serine carboxypeptidase - - - 7.262e-200 639.0
HFD3_k127_2753926_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 464.0
HFD3_k127_2753926_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000581 463.0
HFD3_k127_2753926_4 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005744 387.0
HFD3_k127_2753926_5 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005023 379.0
HFD3_k127_2753926_6 rRNA (cytosine-C5-)-methyltransferase activity K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 332.0
HFD3_k127_2753926_7 Two component transcriptional regulator, LuxR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003914 277.0
HFD3_k127_2753926_8 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000000000000000000000000000006305 258.0
HFD3_k127_2755704_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005301 510.0
HFD3_k127_2755704_1 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.000000000000000008292 85.0
HFD3_k127_2755704_2 - - - - 0.000000000000001266 85.0
HFD3_k127_2755704_3 Pkd domain containing protein K21449 - - 0.00001398 59.0
HFD3_k127_2758520_0 metalloendopeptidase activity K01283 - 3.4.15.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 487.0
HFD3_k127_2758520_1 Periplasmic binding protein domain K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 443.0
HFD3_k127_2790697_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01539 - 3.6.3.9 9.627e-255 804.0
HFD3_k127_2790697_1 Domain of unknown function (DUF5122) beta-propeller - - - 0.00000000000000000000000000000000000000000000000002157 191.0
HFD3_k127_2790697_2 NHL repeat containing protein - - - 0.0000000000000000006582 101.0
HFD3_k127_2795549_0 HAMP domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005885 372.0
HFD3_k127_2795549_1 Two component transcriptional regulator, winged helix family K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 304.0
HFD3_k127_2795549_2 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000001212 183.0
HFD3_k127_2804359_0 Hsp90 protein K04079 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 595.0
HFD3_k127_2804359_1 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007267 482.0
HFD3_k127_2804359_2 trisaccharide binding - - - 0.000000000000000000000000000000000000000000000000000000000000401 226.0
HFD3_k127_2804359_3 Type II/IV secretion system protein K02454 - - 0.0000008634 55.0
HFD3_k127_2808482_0 beta-galactosidase activity - - - 3.901e-276 878.0
HFD3_k127_2808482_1 peptidyl-tyrosine sulfation - - - 2.972e-224 712.0
HFD3_k127_281158_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1593.0
HFD3_k127_281158_1 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006499 539.0
HFD3_k127_281158_2 Large family of predicted nucleotide-binding domains - - - 0.0000000000000000000003409 98.0
HFD3_k127_281158_3 Bacterial type II/III secretion system short domain - - - 0.0000001602 61.0
HFD3_k127_281158_4 Putative prokaryotic signal transducing protein - - - 0.0001929 48.0
HFD3_k127_2812093_0 PA14 - - - 2.707e-220 704.0
HFD3_k127_2812093_1 Protein of unknown function (DUF1552) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005397 602.0
HFD3_k127_2812093_2 PFAM RNP-1 like RNA-binding protein - - - 0.00000000000000000000000000000000002947 137.0
HFD3_k127_2812093_3 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000005133 107.0
HFD3_k127_2814831_0 Glycogen debranching enzyme - - - 0.0 1077.0
HFD3_k127_2814831_1 ASPIC UnbV domain protein - - - 8.45e-218 712.0
HFD3_k127_2814831_2 gluconolactonase activity K13280 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009059 440.0
HFD3_k127_2815720_0 G8 - - - 8.184e-241 767.0
HFD3_k127_2815720_1 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 400.0
HFD3_k127_2815720_2 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001253 276.0
HFD3_k127_2815720_3 ABC-type uncharacterized transport system - - - 0.000000000000003324 89.0
HFD3_k127_2816660_0 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 309.0
HFD3_k127_2816660_1 N-acetylmuramoyl-L-alanine amidase - - - 0.00000000000000000000000000000000000000000000000000000004229 208.0
HFD3_k127_2824961_0 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006 403.0
HFD3_k127_2824961_1 N-terminal TM domain of oligopeptide transport permease C K15582 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003649 291.0
HFD3_k127_2824961_2 Binding-protein-dependent transport system inner membrane component K15581 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 288.0
HFD3_k127_2828367_0 Conserved repeat domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 326.0
HFD3_k127_2828367_1 COG2931 RTX toxins and related Ca2 -binding proteins K01406 - 3.4.24.40 0.000000000000000000000000000000005144 143.0
HFD3_k127_2828367_2 - - - - 0.0000002126 64.0
HFD3_k127_2849299_0 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 392.0
HFD3_k127_2849299_1 PFAM Glycosyl hydrolase family 10 K01181 - 3.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005442 285.0
HFD3_k127_2849299_2 MFS/sugar transport protein K03292 - - 0.0000000000000000000000000000000000000000000000000000000000000000005297 237.0
HFD3_k127_2849299_3 Belongs to the glycosyl hydrolase 43 family - - - 0.000000000008725 74.0
HFD3_k127_2849299_4 esterase K07214 - - 0.0001416 44.0
HFD3_k127_286783_0 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.00000000000000000000000000000001399 136.0
HFD3_k127_2881152_0 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004502 286.0
HFD3_k127_2881152_1 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005812 285.0
HFD3_k127_2883870_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 8.231e-316 1000.0
HFD3_k127_2883870_1 RNA pseudouridylate synthase K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 287.0
HFD3_k127_2883870_2 impB/mucB/samB family K14161 - - 0.00000000000000000000000000000000000000000000000000204 203.0
HFD3_k127_2883870_3 PFAM oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000001776 154.0
HFD3_k127_2883870_4 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000008862 81.0
HFD3_k127_2908582_0 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 604.0
HFD3_k127_2908582_1 and related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 558.0
HFD3_k127_2908582_2 depolymerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 312.0
HFD3_k127_2908582_3 helix_turn_helix, Lux Regulon K07684 - - 0.0000000000000000000000000000000000000000000000000000000000001532 219.0
HFD3_k127_2908582_4 Histidine kinase K07675 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000008154 214.0
HFD3_k127_295359_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 608.0
HFD3_k127_295359_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000525 377.0
HFD3_k127_295359_2 - - - - 0.0000000001896 71.0
HFD3_k127_2973507_0 CotH kinase protein - - - 0.000000000000000000000000000000000000000000000000000000001263 229.0
HFD3_k127_2973507_1 Purple acid Phosphatase, N-terminal domain - - - 0.000000000000000000000000000003993 139.0
HFD3_k127_2973507_3 Glycosyl hydrolases family 16 - - - 0.0000000000000000000000005943 123.0
HFD3_k127_2973507_4 Spore coat protein CotH K01216,K07004 - 3.2.1.73 0.00000000000000001654 98.0
HFD3_k127_2973507_5 domain, Protein - - - 0.0000000000004523 83.0
HFD3_k127_2973507_6 PFAM UBA THIF-type NAD FAD binding protein - - - 0.00004514 55.0
HFD3_k127_2974065_0 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 351.0
HFD3_k127_2974065_1 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.00000000000000000000000000000000000000000000000000000001287 206.0
HFD3_k127_2976694_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005409 510.0
HFD3_k127_2976694_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006926 437.0
HFD3_k127_2976694_2 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006052 291.0
HFD3_k127_2976694_3 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000000000000000000000000000002126 175.0
HFD3_k127_2976694_4 family acetyltransferase - - - 0.000000000000000000000000000000007247 133.0
HFD3_k127_2976694_6 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.000000000000000001055 100.0
HFD3_k127_2976694_7 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.00000000000000244 81.0
HFD3_k127_2976694_8 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.000000001293 68.0
HFD3_k127_2989894_0 alpha beta - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 427.0
HFD3_k127_2989894_1 Beta-lactamase class C K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 350.0
HFD3_k127_2989894_2 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000002409 144.0
HFD3_k127_2989894_3 - - - - 0.000000000000000009167 95.0
HFD3_k127_2989894_4 Protein of unknown function, DUF481 - - - 0.0000000003133 72.0
HFD3_k127_3004356_0 beta-galactosidase activity - - - 2.274e-309 965.0
HFD3_k127_3004356_1 PQQ enzyme repeat - - - 7.525e-301 933.0
HFD3_k127_3004356_2 Mandelate racemase muconate lactonizing enzyme - - - 1.045e-194 612.0
HFD3_k127_3004356_3 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000538 596.0
HFD3_k127_3004356_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 333.0
HFD3_k127_3004356_5 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 308.0
HFD3_k127_3004356_6 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000295 249.0
HFD3_k127_3004356_7 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.000000000000000000000000002748 130.0
HFD3_k127_3004356_8 DNA methylase K07316 - 2.1.1.72 0.000000000000000000000002673 109.0
HFD3_k127_3015626_0 Glutathione S-transferase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005917 471.0
HFD3_k127_3015626_1 PFAM amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 435.0
HFD3_k127_3015626_2 Pterin binding enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004479 284.0
HFD3_k127_3015626_3 Methylenetetrahydrofolate reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000002835 242.0
HFD3_k127_3015626_4 LVIVD repeat - - - 0.000000000000000000000000000000000000000000000000000000000000734 226.0
HFD3_k127_3020906_0 CotH kinase protein - - - 1.058e-277 930.0
HFD3_k127_3020906_1 Spermine/spermidine synthase domain - - - 0.000000000000000000000004158 113.0
HFD3_k127_3020906_2 Fibronectin type 3 domain - - - 0.0000000000000000000001612 116.0
HFD3_k127_3023886_0 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 359.0
HFD3_k127_3023886_1 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001281 274.0
HFD3_k127_3023886_2 CotH kinase protein - - - 0.000000000000000000000000000000000000000000000000000008523 209.0
HFD3_k127_3026136_0 pentaerythritol trinitrate reductase activity - - - 1.575e-235 741.0
HFD3_k127_3026136_1 beta-1,4-mannooligosaccharide phosphorylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 571.0
HFD3_k127_3026136_2 Belongs to the BI1 family K06890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002896 276.0
HFD3_k127_3026136_3 component K15496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001484 276.0
HFD3_k127_3026136_4 Molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001315 261.0
HFD3_k127_3026136_5 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001532 256.0
HFD3_k127_3026573_0 Squalene-hopene cyclase N-terminal domain K06045 - 4.2.1.129,5.4.99.17 5.019e-241 765.0
HFD3_k127_3026573_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 5.071e-221 694.0
HFD3_k127_3028390_0 Cytochrome c - - - 2.777e-315 998.0
HFD3_k127_3028390_1 Glycosyl hydrolases family 43 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 559.0
HFD3_k127_3028390_10 MoaE protein K03635 - 2.8.1.12 0.00000000000000000000001067 107.0
HFD3_k127_3028390_11 Prokaryotic N-terminal methylation motif K02456,K02650 - - 0.000000000000000000006255 102.0
HFD3_k127_3028390_12 thiamine diphosphate biosynthetic process K03154 - - 0.00000007497 59.0
HFD3_k127_3028390_13 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.0000671 52.0
HFD3_k127_3028390_2 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 471.0
HFD3_k127_3028390_3 Converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 421.0
HFD3_k127_3028390_4 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006656 362.0
HFD3_k127_3028390_5 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002954 295.0
HFD3_k127_3028390_6 photoreceptor activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001177 297.0
HFD3_k127_3028390_7 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000008926 277.0
HFD3_k127_3028390_8 Two component transcriptional regulator, LuxR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002829 263.0
HFD3_k127_3028390_9 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000001029 108.0
HFD3_k127_303302_0 Amino acid kinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 528.0
HFD3_k127_303302_1 Domains in Na-Ca exchangers and integrin-beta4 - - - 0.0000000000000000000000002426 120.0
HFD3_k127_3043679_0 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 338.0
HFD3_k127_3043679_1 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001143 276.0
HFD3_k127_3062070_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03320 - - 0.0000000000000000000000000000000000000000000000000000000000001586 244.0
HFD3_k127_3064054_0 fimbrial usher porin activity - - - 0.0 1377.0
HFD3_k127_3064054_1 cell adhesion involved in biofilm formation K13735 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008467 574.0
HFD3_k127_3064054_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 330.0
HFD3_k127_3064054_3 Domain of unknown function DUF11 - - - 0.00000000000000000003322 99.0
HFD3_k127_3064054_4 Pkd domain containing protein - - - 0.0007556 53.0
HFD3_k127_3079323_0 COG3119 Arylsulfatase A K01133 - 3.1.6.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002889 454.0
HFD3_k127_3079323_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 419.0
HFD3_k127_3079323_10 PFAM PBS lyase HEAT-like repeat - - - 0.000004709 59.0
HFD3_k127_3079323_2 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 398.0
HFD3_k127_3079323_3 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002819 380.0
HFD3_k127_3079323_4 Bacterial protein of unknown function (DUF839) K07093 - - 0.0000000000000000000000000000000000000000000000000000000000000005107 254.0
HFD3_k127_3079323_5 - - - - 0.0000000000000000000000000000000000000000000000000000000007144 208.0
HFD3_k127_3079323_6 twin-arginine translocation pathway signal protein K07093 - - 0.000000000000000000000000000000000000000008007 180.0
HFD3_k127_3079323_7 phosphorelay signal transduction system - - - 0.0000000000000000000000004176 117.0
HFD3_k127_3079323_8 TIGRFAM transcriptional regulator, Rrf2 family - - - 0.0000000000000000000000006505 111.0
HFD3_k127_3079323_9 Alginate lyase - - - 0.0000006838 64.0
HFD3_k127_3102184_0 Protein of unknown function (DUF4197) - - - 0.0000000000000000000000000000000000000000000000000000000005345 211.0
HFD3_k127_3102184_1 AsmA family K07289 - - 0.0004847 53.0
HFD3_k127_3129767_0 Peptidase family M28 - - - 3.749e-216 686.0
HFD3_k127_3129767_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533,K17686 - 3.6.3.4,3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 600.0
HFD3_k127_3129767_2 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 561.0
HFD3_k127_3129767_3 CRS1_YhbY K07574 - - 0.000000000002162 73.0
HFD3_k127_3130666_0 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 300.0
HFD3_k127_3130666_1 Nucleotidyl transferase K00971 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004845 306.0
HFD3_k127_3130666_2 Prenyltransferase and squalene oxidase repeat - - - 0.000000000000000000000000000000000000000000000000000000000000005648 237.0
HFD3_k127_3143171_0 COG4166 ABC-type oligopeptide transport system, periplasmic component K15580 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005608 614.0
HFD3_k127_3143171_1 CotH kinase protein - - - 0.0000000000000000000000000000000000000000000000000000000000005387 226.0
HFD3_k127_3143171_2 Oligopeptide K15581 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - 0.0000000000000000000000000000000000007587 157.0
HFD3_k127_3143171_3 Tetratricopeptide TPR_2 repeat protein - - - 0.0001765 53.0
HFD3_k127_3147324_0 polysaccharide deacetylase - - - 0.0 1418.0
HFD3_k127_3147324_1 Dienelactone hydrolase family - - - 1.641e-285 907.0
HFD3_k127_3147324_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009149 398.0
HFD3_k127_3147324_3 polysaccharide deacetylase - - - 0.00000000000000000000003534 103.0
HFD3_k127_3147324_4 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K12980 - - 0.0001299 55.0
HFD3_k127_3150483_0 Allophanate hydrolase subunit 2 - - - 0.00000000000000000000000000000000000000000000000000000000000001066 226.0
HFD3_k127_3150483_1 Belongs to the UPF0271 (lamB) family K07160 - - 0.00000000000000000000000000000000000000000000008203 186.0
HFD3_k127_3150483_2 Allophanate hydrolase subunit 1 K06351 - - 0.000000000000000000000000000000000000001245 151.0
HFD3_k127_3150483_3 Immunoglobulin - - - 0.00000000000000000000000000001272 133.0
HFD3_k127_3150483_4 Pectate lyase K01732,K20276 - 4.2.2.10 0.00000000002907 76.0
HFD3_k127_3158339_0 RNA pseudouridylate synthase K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000001046 190.0
HFD3_k127_3158339_1 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03770 - 5.2.1.8 0.0008397 52.0
HFD3_k127_3164837_0 amino acid-binding ACT domain protein K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 402.0
HFD3_k127_3164837_1 SIS domain K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006926 358.0
HFD3_k127_3164837_2 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 285.0
HFD3_k127_3164837_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000471 261.0
HFD3_k127_3164837_4 Segregation and condensation complex subunit ScpB - - - 0.000000000000000000000000000000000000001453 156.0
HFD3_k127_3189429_0 Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005823 366.0
HFD3_k127_3189429_1 Type IV pilus biogenesis stability protein PilW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 328.0
HFD3_k127_3189429_2 Protein of unknown function (DUF3142) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004995 305.0
HFD3_k127_3189429_3 electron transfer activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001977 267.0
HFD3_k127_3189429_4 DNA-templated transcription, initiation - - - 0.0000000000000000000000000000000000000000000000000000000000000006912 229.0
HFD3_k127_3189429_5 SMART Nucleotide binding protein PINc - - - 0.000000000000000000000000000000000000000000000000000000205 207.0
HFD3_k127_3202218_0 COG2133 Glucose sorbosone dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004556 535.0
HFD3_k127_3202218_1 acid phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 436.0
HFD3_k127_3219939_0 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000006658 220.0
HFD3_k127_3219939_1 SMART Immunoglobulin C2 type - - - 0.0000000000000000000000000000000000000000000009587 192.0
HFD3_k127_3219939_2 PFAM Hemolysin-type calcium-binding region - - - 0.0000000001401 76.0
HFD3_k127_3219939_3 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.0000000007281 72.0
HFD3_k127_3228653_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 5.288e-234 743.0
HFD3_k127_3228653_1 Peptidase family M50 K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003244 488.0
HFD3_k127_3228653_10 Recombination protein O N terminal K03584 - - 0.00000000000000000000007458 109.0
HFD3_k127_3228653_11 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K01489,K03474,K03595,K07042 GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.6.99.2,3.5.4.5 0.00000000000002351 85.0
HFD3_k127_3228653_12 phosphate regulon transcriptional regulatory protein PhoB K07657 - - 0.0000000000003853 81.0
HFD3_k127_3228653_13 NosR regulatory protein - - - 0.00000377 49.0
HFD3_k127_3228653_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008299 388.0
HFD3_k127_3228653_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K11527 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008265 386.0
HFD3_k127_3228653_4 PhoH-like protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 374.0
HFD3_k127_3228653_5 FMN_bind - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 314.0
HFD3_k127_3228653_6 Cytidylyltransferase family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000007793 216.0
HFD3_k127_3228653_7 ApbE family - - - 0.000000000000000000000000000000000000000000000000000003483 214.0
HFD3_k127_3228653_8 HIT domain K19710 - 2.7.7.53 0.0000000000000000000000000000000000000000000000000212 184.0
HFD3_k127_3228653_9 GGDEF domain - - - 0.00000000000000000000000000000000000000000523 170.0
HFD3_k127_3257960_0 WD domain, G-beta repeat - - - 7.248e-218 703.0
HFD3_k127_3257960_1 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007566 597.0
HFD3_k127_3257960_2 ATPases associated with a variety of cellular activities K02056,K10441 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 393.0
HFD3_k127_3257960_3 domain, Protein K00689,K02014,K04744,K07277 - 2.4.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 346.0
HFD3_k127_3257960_4 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.000000000000000000000000000000000000000000000000000000001118 231.0
HFD3_k127_3271341_0 Aldehyde dehydrogenase family K04021 - - 1.923e-197 626.0
HFD3_k127_3271341_1 Zn-dependent dipeptidase, microsomal dipeptidase K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002802 416.0
HFD3_k127_3271341_2 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 348.0
HFD3_k127_3271341_3 amino acid activation for nonribosomal peptide biosynthetic process K03641,K20276 - - 0.0000000000000000000000000000000000000000000000000000000000000001901 254.0
HFD3_k127_3271341_4 Ethanolamine utilisation protein EutN/carboxysome - - - 0.0000000000000000003184 98.0
HFD3_k127_3271341_5 Ethanolamine utilisation protein EutN/carboxysome - - - 0.0000000000000000005943 91.0
HFD3_k127_3271341_6 Ethanolamine utilisation protein EutN/carboxysome K04028 - - 0.000000000001597 68.0
HFD3_k127_3272302_0 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 337.0
HFD3_k127_3272302_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000344 266.0
HFD3_k127_3272302_10 general secretion pathway protein K02456 - - 0.00004497 54.0
HFD3_k127_3272302_2 Domains in Na-Ca exchangers and integrin-beta4 K01406 - 3.4.24.40 0.000000000000000000000000000000000000000000000000000000000000002156 249.0
HFD3_k127_3272302_3 MMPL family K07003 - - 0.00000000000000000000000000000000000000000000000000000000004038 218.0
HFD3_k127_3272302_4 NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000001033 170.0
HFD3_k127_3272302_5 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000004854 157.0
HFD3_k127_3272302_6 twin-arginine translocation pathway signal protein K07093 - - 0.0000000000000000000006743 111.0
HFD3_k127_3272302_7 Lactonase, 7-bladed beta-propeller - - - 0.0000000000000000003095 95.0
HFD3_k127_3272302_8 Fibronectin type 3 domain - - - 0.0000004797 63.0
HFD3_k127_3272302_9 Belongs to the glycosyl hydrolase 43 family K22350 - 1.16.3.3 0.000006639 60.0
HFD3_k127_3287035_0 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008737 499.0
HFD3_k127_3287035_1 Malate/L-lactate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 356.0
HFD3_k127_3287035_2 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003142 289.0
HFD3_k127_3287035_3 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000000000000003937 194.0
HFD3_k127_3294600_0 COG1070 Sugar (pentulose and hexulose) K00848 - 2.7.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 527.0
HFD3_k127_3294600_1 PFAM D-galactarate dehydratase Altronate hydrolase K01685 - 4.2.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 421.0
HFD3_k127_3294600_2 WYL domain K13572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000629 287.0
HFD3_k127_3294600_3 Class II Aldolase and Adducin N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005177 271.0
HFD3_k127_3294600_4 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000000000000000601 216.0
HFD3_k127_3297870_0 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 495.0
HFD3_k127_3297870_1 PFAM type II and III secretion system protein K02666 - - 0.00000000000000000000000000000000000000000000000005612 194.0
HFD3_k127_3297870_2 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000002309 162.0
HFD3_k127_3297870_3 Glycosyl hydrolases family 16 - - - 0.00001691 58.0
HFD3_k127_3308587_0 COG0524 Sugar kinases, ribokinase K00847 - 2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 343.0
HFD3_k127_3308587_1 Stress responsive A/B Barrel Domain - - - 0.0000000000000000000002405 100.0
HFD3_k127_3308587_2 Cytochrome c - - - 0.000000000000000007418 89.0
HFD3_k127_3310626_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 8.169e-232 722.0
HFD3_k127_3310626_1 Trehalose utilisation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 321.0
HFD3_k127_3310626_2 - - - - 0.0000000000000000000000000000000003897 151.0
HFD3_k127_3310626_3 PFAM ROK family K00845 - 2.7.1.2 0.0000000002275 72.0
HFD3_k127_3310626_4 - - - - 0.00000000158 66.0
HFD3_k127_3310626_5 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.0000005352 53.0
HFD3_k127_3315491_0 CotH kinase protein - - - 1.097e-316 1015.0
HFD3_k127_3318577_0 Glycosyl hydrolases family 32 K01212,K03332 - 3.2.1.65,3.2.1.80 5.411e-254 803.0
HFD3_k127_3318577_1 metallocarboxypeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005085 507.0
HFD3_k127_3318577_2 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.00000000000004256 73.0
HFD3_k127_3318577_3 EF hand - - - 0.000000000000069 79.0
HFD3_k127_3323206_0 ABC transporter K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003566 462.0
HFD3_k127_3323206_1 PFAM ABC transporter transmembrane region K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007277 421.0
HFD3_k127_3323206_2 PFAM Cache K08738 - - 0.00000000000000000000000000000000000000000000000000000000000001003 241.0
HFD3_k127_3323206_3 PFAM Cupin 2 conserved barrel domain protein - - - 0.000000000000000000004275 109.0
HFD3_k127_3323206_4 Cache_2 - - - 0.00000000009998 75.0
HFD3_k127_3323206_5 Domain of unknown function (DUF4190) - - - 0.0000000008964 71.0
HFD3_k127_3323206_6 Cupin - - - 0.0000000009165 72.0
HFD3_k127_3328220_0 Aldolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007096 432.0
HFD3_k127_3328220_1 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007047 390.0
HFD3_k127_3328220_2 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005162 321.0
HFD3_k127_3328220_3 Aminotransferase class-V - - - 0.00000000000000000000000000001483 119.0
HFD3_k127_3345435_0 Protein of unknown function (DUF1501) - - - 3.811e-211 672.0
HFD3_k127_3345435_1 PFAM RNP-1 like RNA-binding protein - - - 0.0000000000000000000000000000000001373 135.0
HFD3_k127_3348114_0 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006986 569.0
HFD3_k127_3348114_1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006165 539.0
HFD3_k127_3348114_2 Dehydrogenase E1 component K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 440.0
HFD3_k127_3348114_3 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 305.0
HFD3_k127_3348114_4 Prenyltransferase and squalene oxidase repeat - - - 0.000000000000006419 74.0
HFD3_k127_3373793_0 anaphase-promoting complex binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004695 422.0
HFD3_k127_3373793_1 Tricorn protease C1 domain K08676 - - 0.0000000000000000000000000000000000001209 143.0
HFD3_k127_3384997_0 Transport and Golgi organisation 2 K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005655 398.0
HFD3_k127_3384997_1 PFAM regulatory protein LuxR - - - 0.000000000000000000000000000000000000000000000000000000000000000003982 237.0
HFD3_k127_3384997_2 ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000001673 232.0
HFD3_k127_3386921_0 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000474 190.0
HFD3_k127_3386921_1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000000000000000000000000000000000000000007755 177.0
HFD3_k127_3386921_2 Galactose oxidase, central domain - - - 0.000000002395 68.0
HFD3_k127_3395516_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 6.128e-231 727.0
HFD3_k127_3395516_1 cytochrome C - - - 1.637e-199 644.0
HFD3_k127_3395516_2 YaeQ - - - 0.000008079 55.0
HFD3_k127_3419895_0 PhoPQ-activated pathogenicity-related protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 527.0
HFD3_k127_3419895_1 Purple acid Phosphatase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 413.0
HFD3_k127_3419895_2 Bacterial Ig-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 378.0
HFD3_k127_3419895_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000002065 240.0
HFD3_k127_3419895_4 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000001816 115.0
HFD3_k127_3464780_0 Glucose / Sorbosone dehydrogenase - - - 4.687e-232 748.0
HFD3_k127_3464780_1 Alcohol dehydrogenase GroES domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006639 509.0
HFD3_k127_3464780_10 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000003366 101.0
HFD3_k127_3464780_11 general secretion pathway protein K02456 - - 0.0000000000005795 76.0
HFD3_k127_3464780_12 Cytochrome c - - - 0.000001833 53.0
HFD3_k127_3464780_2 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009865 511.0
HFD3_k127_3464780_3 Pyruvate kinase, alpha/beta domain K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 493.0
HFD3_k127_3464780_4 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003665 417.0
HFD3_k127_3464780_5 PFAM Peptidase M16 inactive domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 377.0
HFD3_k127_3464780_6 Glutamyl-tRNAGlu reductase, N-terminal domain K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 291.0
HFD3_k127_3464780_7 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001136 294.0
HFD3_k127_3464780_8 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000001737 228.0
HFD3_k127_3464780_9 PFAM Cytochrome c assembly protein - - - 0.000000000000000000000002974 113.0
HFD3_k127_3467338_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 415.0
HFD3_k127_3467338_1 Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) K07337 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 294.0
HFD3_k127_3467338_2 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008416 295.0
HFD3_k127_3467338_3 Enoyl- acyl-carrier-protein reductase NADH K00208 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006950,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0033554,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051716,GO:0055114,GO:0065003,GO:0070417,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000003371 161.0
HFD3_k127_3467338_4 PFAM Major Facilitator Superfamily - - - 0.000001258 61.0
HFD3_k127_3502529_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 3.457e-221 701.0
HFD3_k127_3502529_1 Peptidase family M3 K08602 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008677 538.0
HFD3_k127_3502529_2 Seryl-tRNA synthetase N-terminal domain K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009504 459.0
HFD3_k127_3502529_3 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008973 433.0
HFD3_k127_3502529_4 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000006649 193.0
HFD3_k127_3502529_5 Cupin 2, conserved barrel domain protein - - - 0.00000000000003338 78.0
HFD3_k127_3545344_0 - - - - 0.00000000000000000000000000000000000000000001805 187.0
HFD3_k127_3545344_1 Haemolysin-type calcium-binding repeat (2 copies) K01406 - 3.4.24.40 0.000000000000000000000000000000000000000002636 180.0
HFD3_k127_3545344_2 - - - - 0.00000000000143 78.0
HFD3_k127_3548081_0 ABC-type multidrug transport system ATPase and permease K06147 - - 3.502e-215 684.0
HFD3_k127_3548081_1 glycosyl transferase - - - 0.00000000000000215 83.0
HFD3_k127_3548081_2 PFAM Glycosyl transferase, group 1 - - - 0.000000001409 60.0
HFD3_k127_3550721_0 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 367.0
HFD3_k127_3550721_1 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000002876 248.0
HFD3_k127_3550721_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000001184 231.0
HFD3_k127_3550721_3 arginine decarboxylase K01585 - 4.1.1.19 0.000000000000000000000000000004446 122.0
HFD3_k127_3550721_4 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.000000000000000000000000000009143 123.0
HFD3_k127_3553469_0 lactate racemase activity K22373 - 5.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000459 578.0
HFD3_k127_3553469_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 418.0
HFD3_k127_3555895_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000003679 275.0
HFD3_k127_3555895_1 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000002102 252.0
HFD3_k127_3555895_2 Pfam:DUF59 - - - 0.0000000000000000000000000000000000000000000000000000006969 198.0
HFD3_k127_3555895_3 Peptidase M48 K06013 - 3.4.24.84 0.000000000000000512 79.0
HFD3_k127_3563076_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 3.689e-277 874.0
HFD3_k127_3563076_1 Domain of unknown function (DUF5060) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 397.0
HFD3_k127_3563076_2 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 340.0
HFD3_k127_3563076_3 COGs COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM CutM homologs K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000003786 263.0
HFD3_k127_3563076_4 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000006162 234.0
HFD3_k127_3563076_5 Carbon monoxide dehydrogenase subunit G (CoxG) K09386 - - 0.000000000000000000000000000000006906 133.0
HFD3_k127_3563664_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 579.0
HFD3_k127_3563664_1 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002753 248.0
HFD3_k127_3563664_2 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000002948 189.0
HFD3_k127_3563664_3 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000002261 178.0
HFD3_k127_3563664_4 PFAM response regulator receiver - - - 0.000000000000000000000000000000000001418 142.0
HFD3_k127_3563664_5 Two component regulator propeller - - - 0.0000000000000000007145 98.0
HFD3_k127_3563664_6 Subtilase family K13274,K20276 - - 0.00000000000000006214 94.0
HFD3_k127_356829_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 6.946e-283 888.0
HFD3_k127_356829_1 Amidohydrolase family K06015 - 3.5.1.81 1.369e-244 775.0
HFD3_k127_356829_10 Zinc metalloprotease (Elastase) K09607 - - 0.00000000000000000000007868 115.0
HFD3_k127_356829_11 cellulase activity - - - 0.00002576 56.0
HFD3_k127_356829_12 domain protein - - - 0.0003447 52.0
HFD3_k127_356829_2 PFAM MgtE intracellular K02383 - - 3.042e-213 726.0
HFD3_k127_356829_4 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 295.0
HFD3_k127_356829_5 ATPase, AAA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003061 286.0
HFD3_k127_356829_6 Glutathione peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005736 243.0
HFD3_k127_356829_7 Hep Hag repeat protein - - - 0.0000000000000000000000000000000000002287 160.0
HFD3_k127_356829_8 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000256 122.0
HFD3_k127_356829_9 - - - - 0.00000000000000000000000001356 124.0
HFD3_k127_3580681_0 Domain of unknown function (DUF4976) - - - 1.041e-213 679.0
HFD3_k127_3580681_1 D-alanine [D-alanyl carrier protein] ligase activity - - - 5.472e-210 663.0
HFD3_k127_3593765_0 sequence-specific DNA binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005948 285.0
HFD3_k127_3593765_1 thiolester hydrolase activity K11750 - - 0.000000000000000000000000000001769 130.0
HFD3_k127_3595274_0 ASPIC UnbV domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003295 439.0
HFD3_k127_3595274_1 CbiX - - - 0.000000000000000000000000000000000000000000000000000000000001127 217.0
HFD3_k127_3602152_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 6.392e-240 754.0
HFD3_k127_3602152_1 Heavy-metal-associated domain K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004809 623.0
HFD3_k127_3602152_2 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000642 224.0
HFD3_k127_3602152_3 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000001256 150.0
HFD3_k127_3602152_4 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000007227 146.0
HFD3_k127_3602152_5 Lipid A Biosynthesis N-terminal domain - - - 0.000000000000000000000000000002201 124.0
HFD3_k127_3602940_0 anaphase-promoting complex binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005669 487.0
HFD3_k127_3602940_1 and related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 407.0
HFD3_k127_3602940_2 and related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007579 351.0
HFD3_k127_3602940_3 - - - - 0.0001486 49.0
HFD3_k127_362776_0 Amylo-alpha-1,6-glucosidase - - - 5.902e-244 771.0
HFD3_k127_362776_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004654 499.0
HFD3_k127_363796_0 PFAM MgtE intracellular K02383 - - 5.6e-229 775.0
HFD3_k127_363796_1 PFAM RNA-directed DNA polymerase (Reverse transcriptase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 485.0
HFD3_k127_363796_2 carboxylic acid catabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008568 468.0
HFD3_k127_363796_3 D,D-heptose 1,7-bisphosphate phosphatase K03273 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 417.0
HFD3_k127_363796_4 PFAM GHMP kinase K07031 - 2.7.1.168 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 395.0
HFD3_k127_363796_6 Nad-dependent epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 324.0
HFD3_k127_363796_7 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000001413 180.0
HFD3_k127_363796_8 domain, Protein K03561,K12287 - - 0.0001085 56.0
HFD3_k127_3660076_0 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007552 336.0
HFD3_k127_3660076_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01874 - 6.1.1.10 0.00000000000000000000000000000000000000000000000000007936 189.0
HFD3_k127_3660076_2 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000001781 150.0
HFD3_k127_3660076_3 PFAM Tetratricopeptide - - - 0.00002981 54.0
HFD3_k127_3672517_0 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006473 345.0
HFD3_k127_3672517_1 Domain of unknown function (DUF1731) K07071 - - 0.000000000000003387 86.0
HFD3_k127_3672517_2 ubiE/COQ5 methyltransferase family - - - 0.00007967 53.0
HFD3_k127_3673224_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1062.0
HFD3_k127_3698322_0 Anticodon binding domain K01880 - 6.1.1.14 6.628e-252 789.0
HFD3_k127_3698322_1 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 6.004e-246 778.0
HFD3_k127_3698322_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01885,K01894 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000001679 210.0
HFD3_k127_3698322_3 metal cluster binding K06940 - - 0.0000000000000000000000000000002036 137.0
HFD3_k127_3698322_4 Transcription termination factor nusG K05785 - - 0.00000000000000000000002009 104.0
HFD3_k127_3698322_5 Multidrug transporter - - - 0.00000000009615 68.0
HFD3_k127_3700136_0 Two component transcriptional regulator, LuxR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 289.0
HFD3_k127_3700136_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000004766 217.0
HFD3_k127_3700136_2 Histidine kinase K20974 - 2.7.13.3 0.000000000000000000000000000000000468 151.0
HFD3_k127_370114_0 response to antibiotic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 441.0
HFD3_k127_3715237_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 8.679e-280 882.0
HFD3_k127_3715237_1 Protein of unknown function (DUF1501) - - - 1.242e-228 715.0
HFD3_k127_3715237_2 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 354.0
HFD3_k127_3715237_3 Choline/ethanolamine kinase - - - 0.000000000000000000000000000000000000000000000000000000009053 212.0
HFD3_k127_3715237_4 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus - - - 0.0000000000000000000000000000000001878 138.0
HFD3_k127_3715237_5 CotH kinase protein - - - 0.000000000000000000000000000000004436 146.0
HFD3_k127_3715237_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA K02956 - - 0.000000000000000000000000006593 111.0
HFD3_k127_3760509_0 Oxidoreductase family, C-terminal alpha/beta domain - - - 1.697e-208 653.0
HFD3_k127_3760509_1 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005099 361.0
HFD3_k127_3760509_2 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004792 317.0
HFD3_k127_3760509_3 chlorophyll binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000001157 261.0
HFD3_k127_3760509_4 UbiA prenyltransferase family K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000003418 231.0
HFD3_k127_3760509_5 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.0000000000000000000000000000000000000002345 168.0
HFD3_k127_3760509_6 Erythromycin esterase - - - 0.00000001251 69.0
HFD3_k127_3782858_0 SMART Pyrrolo-quinoline quinone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 563.0
HFD3_k127_3782858_1 Belongs to the pseudouridine synthase RsuA family K06181 - 5.4.99.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001665 282.0
HFD3_k127_3782858_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006526 295.0
HFD3_k127_3782858_3 acid phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000214 242.0
HFD3_k127_3785367_0 Carbamoyltransferase C-terminus K00612 - - 8.327e-296 917.0
HFD3_k127_3785367_1 transferase activity, transferring glycosyl groups K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 566.0
HFD3_k127_3785367_10 GtrA-like protein - - - 0.00000000000000000000002324 104.0
HFD3_k127_3785367_11 lipolytic protein G-D-S-L family - - - 0.0000000000000000169 94.0
HFD3_k127_3785367_12 - - - - 0.0000000000000006461 83.0
HFD3_k127_3785367_13 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000007061 91.0
HFD3_k127_3785367_14 - - - - 0.0000000000002341 76.0
HFD3_k127_3785367_15 Bacterial membrane protein YfhO - - - 0.000000000009318 79.0
HFD3_k127_3785367_16 Haemolysin-type calcium-binding repeat (2 copies) K01406 - 3.4.24.40 0.0002116 52.0
HFD3_k127_3785367_2 UDP binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 505.0
HFD3_k127_3785367_3 GDP-mannose 4,6 dehydratase K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003864 485.0
HFD3_k127_3785367_4 Bacterial sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004535 406.0
HFD3_k127_3785367_5 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 364.0
HFD3_k127_3785367_6 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006098 350.0
HFD3_k127_3785367_7 Type II and III secretion system protein K02453 - - 0.00000000000000000000000000000000000000000000000000000000006108 233.0
HFD3_k127_3785367_8 Helix-hairpin-helix class 2 (Pol1 family) motifs K02335 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000734 205.0
HFD3_k127_3785367_9 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000000000000000000004019 144.0
HFD3_k127_379327_0 Asparagine synthase K01953 - 6.3.5.4 5.359e-258 811.0
HFD3_k127_379327_1 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 419.0
HFD3_k127_379327_2 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000586 411.0
HFD3_k127_379327_3 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 363.0
HFD3_k127_379327_4 PFAM Radical SAM domain protein K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006717 361.0
HFD3_k127_379327_5 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004544 293.0
HFD3_k127_379327_6 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000006558 217.0
HFD3_k127_379327_7 ATP hydrolysis coupled proton transport - - - 0.000000000000000000000000000000000000001261 160.0
HFD3_k127_379327_8 GDSL-like Lipase/Acylhydrolase family - - - 0.000000003827 59.0
HFD3_k127_3799234_0 Pfam:KaiC K08482 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 537.0
HFD3_k127_3799234_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002476 276.0
HFD3_k127_3817338_0 CotH kinase protein - - - 1.898e-261 876.0
HFD3_k127_3817338_1 Di-glucose binding within endoplasmic reticulum - - - 0.000000000000000000000000000000000000002902 171.0
HFD3_k127_3838116_0 Type IV secretion-system coupling protein DNA-binding domain K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005929 479.0
HFD3_k127_3838116_1 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005687 431.0
HFD3_k127_3838116_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001204 260.0
HFD3_k127_3838116_3 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000001368 213.0
HFD3_k127_3838116_4 - - - - 0.000000001677 64.0
HFD3_k127_3844312_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008133 399.0
HFD3_k127_3844312_1 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000000000000009 184.0
HFD3_k127_3844312_2 Spore coat protein CotH K01216,K07004 - 3.2.1.73 0.00000000000000000000001847 117.0
HFD3_k127_3844312_3 Regulator of chromosome condensation (RCC1) repeat - - - 0.0000000000000000007463 102.0
HFD3_k127_3844312_4 Belongs to the glycosyl hydrolase 2 family - - - 0.00000000002769 78.0
HFD3_k127_3844312_5 Carbohydrate binding domain X2 - - - 0.0002853 54.0
HFD3_k127_3850017_0 Squalene-hopene cyclase N-terminal domain - - - 2.041e-206 661.0
HFD3_k127_3850017_1 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000514 604.0
HFD3_k127_3850017_2 Acyl transferase domain K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005309 293.0
HFD3_k127_3850017_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000001365 124.0
HFD3_k127_3851789_0 Sugar (and other) transporter - - - 5.888e-221 692.0
HFD3_k127_3851789_1 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 593.0
HFD3_k127_3851789_10 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001196 252.0
HFD3_k127_3851789_11 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000000000000000000001002 229.0
HFD3_k127_3851789_12 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000001066 217.0
HFD3_k127_3851789_13 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000006206 213.0
HFD3_k127_3851789_14 tRNA binding K02878 GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000008728 198.0
HFD3_k127_3851789_15 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000004334 196.0
HFD3_k127_3851789_16 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.0000000000000000000000000000000000000000000000000003425 186.0
HFD3_k127_3851789_17 Binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000000000003864 178.0
HFD3_k127_3851789_18 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000122 171.0
HFD3_k127_3851789_19 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000002552 151.0
HFD3_k127_3851789_2 heme-binding domain, Pirellula Verrucomicrobium type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003105 549.0
HFD3_k127_3851789_20 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.0000000000000000000000000000000003738 132.0
HFD3_k127_3851789_21 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000000001627 130.0
HFD3_k127_3851789_22 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000002249 129.0
HFD3_k127_3851789_23 Ribosomal protein L17 K02879 - - 0.00000000000000000000000000000008222 130.0
HFD3_k127_3851789_24 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.000000000000000000000000000002064 123.0
HFD3_k127_3851789_25 - - - - 0.00000000000000000000000001227 119.0
HFD3_k127_3851789_26 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000002848 111.0
HFD3_k127_3851789_27 Ribosomal proteins 50S L24/mitochondrial 39S L24 K02895 - - 0.0000000000000000000000001066 110.0
HFD3_k127_3851789_28 pfkB family carbohydrate kinase - - - 0.000000000000002028 87.0
HFD3_k127_3851789_29 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000001459 74.0
HFD3_k127_3851789_3 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 475.0
HFD3_k127_3851789_30 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000001993 68.0
HFD3_k127_3851789_31 Ribosomal L29 protein K02904 - - 0.000000006949 61.0
HFD3_k127_3851789_32 MacB-like periplasmic core domain K02004 - - 0.00004521 54.0
HFD3_k127_3851789_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009997 466.0
HFD3_k127_3851789_5 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000462 347.0
HFD3_k127_3851789_6 Spore coat protein CotH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000452 334.0
HFD3_k127_3851789_7 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 299.0
HFD3_k127_3851789_8 Metallopeptidase family M24 K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 290.0
HFD3_k127_3851789_9 lipoprotein transporter activity K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 287.0
HFD3_k127_3875868_0 Amidohydrolase family - - - 2.379e-227 719.0
HFD3_k127_3875868_1 SMART Pyrrolo-quinoline quinone K17713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 393.0
HFD3_k127_3875868_2 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000002677 192.0
HFD3_k127_3875868_3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000000000000000000008734 125.0
HFD3_k127_3883447_0 Lysine-2,3-aminomutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 541.0
HFD3_k127_3883447_1 SNF2 family N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 475.0
HFD3_k127_3883447_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 316.0
HFD3_k127_3883447_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 301.0
HFD3_k127_3883447_5 Biotin/lipoate A/B protein ligase family K03800 - 6.3.1.20 0.000000000000000000000000000000006789 136.0
HFD3_k127_3883447_6 PFAM peptidase S16 lon domain protein K01338 - 3.4.21.53 0.00000000000000000000000000000002811 134.0
HFD3_k127_3883447_7 Putative regulatory protein - - - 0.000000000000000000000000000007891 124.0
HFD3_k127_3893473_0 IgGFc binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008379 335.0
HFD3_k127_3893473_1 HAD-hyrolase-like K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008096 316.0
HFD3_k127_3893473_2 Oxygen tolerance - - - 0.0000000000000000000000000000000000001781 163.0
HFD3_k127_3893473_3 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000001614 77.0
HFD3_k127_3893473_4 bacterial-type flagellum-dependent cell motility - - - 0.00002993 57.0
HFD3_k127_3900910_0 Beta-ketoacyl synthase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004085 474.0
HFD3_k127_3900910_1 response to antibiotic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 479.0
HFD3_k127_3900910_2 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004731 303.0
HFD3_k127_3900910_3 Beta-ketoacyl synthase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000005515 254.0
HFD3_k127_3900910_4 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000001839 128.0
HFD3_k127_3900910_5 Phosphopantetheine attachment site - - - 0.0000000000000000002299 94.0
HFD3_k127_3900910_6 Belongs to the glycosyl hydrolase family 6 K01218 - 3.2.1.78 0.00002567 59.0
HFD3_k127_392404_0 PFAM peptidase S1 and S6 chymotrypsin Hap K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009675 385.0
HFD3_k127_392404_1 positive regulation of acetylcholine metabolic process K06910 - - 0.000000000000000000000000000000000000000000000000000000003582 202.0
HFD3_k127_392500_0 Planctomycete cytochrome C - - - 1.808e-253 798.0
HFD3_k127_392500_1 Protein of unknown function (DUF1501) - - - 1.799e-251 786.0
HFD3_k127_392500_2 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 471.0
HFD3_k127_392500_3 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000001591 229.0
HFD3_k127_392500_4 Protein of unknown function (DUF3494) - - - 0.000000000000000000000000000000000000000000000018 195.0
HFD3_k127_3931778_0 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second K01958 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.4.1.1 0.0 1836.0
HFD3_k127_3931778_1 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 358.0
HFD3_k127_3931778_2 PFAM Metal-dependent hydrolase HDOD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009131 267.0
HFD3_k127_3931778_3 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000000101 145.0
HFD3_k127_3931778_4 DNA topoisomerase IV subunit B - - - 0.0000000000009529 80.0
HFD3_k127_3931778_5 Anti-sigma factor - - - 0.00000000009322 67.0
HFD3_k127_3947830_0 Belongs to the glycosyl hydrolase 43 family K22350 - 1.16.3.3 3.154e-220 747.0
HFD3_k127_3947830_1 CotH kinase protein - - - 0.000000000000000000000000000000000000000000000000000000000000000006337 258.0
HFD3_k127_3947830_2 May be involved in cell division K05803 - - 0.00000000000000000000000000000000000000000000000000000000000000008154 233.0
HFD3_k127_3947830_3 Immunoglobulin I-set domain protein - - - 0.000000000001364 83.0
HFD3_k127_3947830_4 Erythromycin esterase - - - 0.00000000001616 79.0
HFD3_k127_3947830_5 Glucose / Sorbosone dehydrogenase - - - 0.0000004934 64.0
HFD3_k127_3961466_0 ASPIC UnbV domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 310.0
HFD3_k127_3961466_1 PFAM LemA family protein K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000007522 234.0
HFD3_k127_3961466_2 TPM domain K06872 - - 0.0000000000000000000000000000000000000000000000000105 196.0
HFD3_k127_3961466_3 TPM domain - - - 0.000000000000000000000000000000000000001371 151.0
HFD3_k127_3974467_0 Heavy metal translocating P-type atpase K01534,K17686 - 3.6.3.3,3.6.3.5,3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 452.0
HFD3_k127_3974467_1 stress-induced mitochondrial fusion - - - 0.0000000000000000000000000001437 127.0
HFD3_k127_3974467_2 HflC and HflK could regulate a protease K04087 - - 0.00000000000000000000000003631 119.0
HFD3_k127_3974467_3 HflC and HflK could encode or regulate a protease K04088 - - 0.0000000000000000000000002308 119.0
HFD3_k127_398082_0 Cytochrome c, class I - - - 1.348e-284 891.0
HFD3_k127_398082_1 Protein of unknown function (DUF1501) - - - 2.446e-202 640.0
HFD3_k127_398082_2 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 292.0
HFD3_k127_3983457_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 529.0
HFD3_k127_3983457_1 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003147 284.0
HFD3_k127_3983457_2 PFAM Prenyltransferase squalene oxidase K06045 - 4.2.1.129,5.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000001314 263.0
HFD3_k127_3983457_3 IMG reference gene - - - 0.00000004784 63.0
HFD3_k127_4016612_0 PFAM Xylose isomerase domain protein TIM barrel - - - 9.04e-214 671.0
HFD3_k127_4016612_1 Alanine dehydrogenase/PNT, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008669 565.0
HFD3_k127_4016612_2 Putative RNA methylase family UPF0020 K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000007105 224.0
HFD3_k127_4016612_3 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000003751 186.0
HFD3_k127_4016612_4 PFAM ribonuclease BN K07058 - - 0.00000000000000000000000000000000000001026 165.0
HFD3_k127_4023551_0 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K07093 - - 0.00000000000000000000000000000000000000000000000000000000001418 238.0
HFD3_k127_4023551_1 CotH kinase protein - - - 0.00000000000000000000000000000000000000000000000000000000051 233.0
HFD3_k127_4023551_2 Glucose / Sorbosone dehydrogenase K00428,K01728 - 1.11.1.5,4.2.2.2 0.00000000000000000000000001814 129.0
HFD3_k127_4023551_3 metallopeptidase activity K01179,K04618 - 1.1.3.9,3.2.1.4 0.00004155 58.0
HFD3_k127_404333_0 homoserine kinase activity K02204 - 2.7.1.39 0.0 1408.0
HFD3_k127_404333_1 Belongs to the PEP-utilizing enzyme family K01006,K01007 - 2.7.9.1,2.7.9.2 1.291e-267 858.0
HFD3_k127_404333_2 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 318.0
HFD3_k127_4048895_0 Helix-hairpin-helix containing domain - - - 1.408e-310 966.0
HFD3_k127_4048895_1 cellulase activity K01361,K13277,K20276 - 3.4.21.96 7.028e-249 790.0
HFD3_k127_4048895_10 Transporter K03455 - - 0.000000000000888 70.0
HFD3_k127_4048895_2 ASPIC and UnbV K21162 - - 3.677e-225 721.0
HFD3_k127_4048895_3 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 517.0
HFD3_k127_4048895_4 Major Facilitator Superfamily K08191 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 405.0
HFD3_k127_4048895_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004692 420.0
HFD3_k127_4048895_6 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012,K00066 GO:0000271,GO:0003674,GO:0003824,GO:0003979,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016491,GO:0016614,GO:0016616,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046377,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901576 1.1.1.132,1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007853 398.0
HFD3_k127_4048895_7 FMN binding K00347,K21163 GO:0000166,GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008144,GO:0008150,GO:0008152,GO:0010181,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0019842,GO:0030001,GO:0030964,GO:0032553,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044425,GO:0044464,GO:0048037,GO:0050136,GO:0050662,GO:0051179,GO:0051234,GO:0055114,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:1901265,GO:1901363,GO:1902444,GO:1902494 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007591 290.0
HFD3_k127_4048895_8 Belongs to the binding-protein-dependent transport system permease family K10440,K17203 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000254 263.0
HFD3_k127_4048895_9 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000007266 178.0
HFD3_k127_4059084_0 protein transport across the cell outer membrane K02453,K03219 - - 0.000000000000000000000000000000000000000001262 173.0
HFD3_k127_4059084_1 PFAM type II and III secretion system protein K02453 - - 0.0002451 48.0
HFD3_k127_4066171_0 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005732 370.0
HFD3_k127_4066171_1 Belongs to the TPP enzyme family K07004 - - 0.000000000000000005761 87.0
HFD3_k127_4066171_2 - - - - 0.00000007239 62.0
HFD3_k127_406964_0 MatE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 561.0
HFD3_k127_406964_1 Planctomycete cytochrome C - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 489.0
HFD3_k127_406964_2 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 417.0
HFD3_k127_406964_3 Bacterial Ig-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 380.0
HFD3_k127_406964_4 Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008723 342.0
HFD3_k127_406964_5 Heparinase II/III-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 330.0
HFD3_k127_406964_6 coenzyme F390 K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000002266 276.0
HFD3_k127_406964_7 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000001937 179.0
HFD3_k127_406964_8 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.00000000000000000000000000009832 134.0
HFD3_k127_4075515_0 SMART PAS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 544.0
HFD3_k127_4075515_1 Metallo-peptidase family M12B Reprolysin-like - - - 0.000002444 59.0
HFD3_k127_4098473_0 Glucose / Sorbosone dehydrogenase - - - 0.0 1169.0
HFD3_k127_4098473_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000549 309.0
HFD3_k127_4109021_0 Ketoacyl-synthetase C-terminal extension - - - 0.0 1111.0
HFD3_k127_4115267_0 PFAM peptidase M16 domain protein K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 317.0
HFD3_k127_4115267_1 - - - - 0.00000000000000000000000000000001069 134.0
HFD3_k127_4115267_2 iron ion homeostasis - - - 0.00000000000002814 80.0
HFD3_k127_4125626_0 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 530.0
HFD3_k127_4125626_1 Glycosyl hydrolases family 39 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 491.0
HFD3_k127_4125626_2 Belongs to the ABC transporter superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003445 410.0
HFD3_k127_4125626_3 Belongs to the ABC transporter superfamily K02031,K02032,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005107 347.0
HFD3_k127_4125626_4 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 334.0
HFD3_k127_4125626_5 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 321.0
HFD3_k127_4125626_6 Ankyrin repeats (many copies) K06015,K06867,K06886 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001078 314.0
HFD3_k127_4125626_7 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067,K06192 - - 0.00000000000000000000000000000000000000000000000000001036 201.0
HFD3_k127_4125626_8 ABC-type transport auxiliary lipoprotein component K18480 - - 0.0000000000000000000005675 105.0
HFD3_k127_4125626_9 Planctomycete cytochrome C - - - 0.00000000000000000007174 106.0
HFD3_k127_4143687_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 355.0
HFD3_k127_4143687_1 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity K02372,K16363 - 3.5.1.108,4.2.1.59 0.0000000000000000000006567 100.0
HFD3_k127_4143687_2 oxidoreductase activity, acting on CH-OH group of donors K10780 - 1.3.1.104 0.000000000000000000004852 97.0
HFD3_k127_4148366_0 DEAD DEAH box helicase domain protein - - - 1.223e-215 694.0
HFD3_k127_4148366_1 PFAM phosphoesterase, RecJ domain protein K07462 - - 0.00000000000000000000000000000000000000000000000000001942 198.0
HFD3_k127_4150604_0 Cellulase (glycosyl hydrolase family 5) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006473 421.0
HFD3_k127_4150604_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000003262 119.0
HFD3_k127_4150604_2 - - - - 0.0000000000000003033 82.0
HFD3_k127_4150604_3 - - - - 0.000000696 55.0
HFD3_k127_415112_0 Belongs to the pseudouridine synthase RsuA family K06183 - 5.4.99.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000003265 260.0
HFD3_k127_415112_1 Bacterial protein of unknown function (DUF839) K07093 - - 0.000000000000000000000000000000000000000000000000000000000000001038 250.0
HFD3_k127_415112_2 Permease MlaE K02066 - - 0.0000000000000000000000000000000301 138.0
HFD3_k127_415112_3 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system K02071 - - 0.00000000000000000000000004937 120.0
HFD3_k127_415112_4 MlaD protein K02067 - - 0.000003731 59.0
HFD3_k127_4155087_0 N-acetylglucosaminylinositol deacetylase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007606 473.0
HFD3_k127_4155087_1 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000243 297.0
HFD3_k127_4155087_2 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003665 256.0
HFD3_k127_4155087_3 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000006599 265.0
HFD3_k127_4155087_4 protein localization to T-tubule K21440 - - 0.0000000000000000000000000000000000008935 161.0
HFD3_k127_4172580_0 Alpha-L-rhamnosidase N-terminal domain K05989 - 3.2.1.40 2.169e-211 672.0
HFD3_k127_4172580_1 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004551 530.0
HFD3_k127_417781_0 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 325.0
HFD3_k127_417781_1 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000001832 160.0
HFD3_k127_4178421_0 CotH kinase protein - - - 7.103e-228 754.0
HFD3_k127_4184248_0 COG2804 Type II secretory pathway ATPase PulE Tfp pilus assembly pathway ATPase PilB K02454,K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007364 487.0
HFD3_k127_4184248_1 Type 4 fimbrial assembly protein pilC K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000009689 238.0
HFD3_k127_4184248_2 general secretion pathway protein K02246,K02456 - - 0.00000000000000000000000000000004296 132.0
HFD3_k127_4184248_3 Type II secretion system (T2SS), protein K - - - 0.000000000000000000000000000002169 138.0
HFD3_k127_4184248_4 Prokaryotic N-terminal methylation motif - - - 0.0001377 52.0
HFD3_k127_4197223_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 1.176e-196 627.0
HFD3_k127_4197223_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 436.0
HFD3_k127_4197223_2 TIGRFAM DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006823 358.0
HFD3_k127_4197223_3 WD40 repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 308.0
HFD3_k127_4197223_4 Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 K00773,K07319,K11782,K15461 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0004808,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363 2.1.1.61,2.1.1.72,2.4.2.29,4.2.1.151 0.00000000000000000000000000000000000000000000000000000000000000000000007294 249.0
HFD3_k127_4197223_5 Lrp/AsnC ligand binding domain - - - 0.0000000000000000000000000000000000000000000000000000006713 203.0
HFD3_k127_4197223_6 pathogenesis - - - 0.0000000000000000000000000000000000000000000000006267 200.0
HFD3_k127_4197223_7 Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions K09913 - 2.4.2.1,2.4.2.2 0.000000000000000000000000000000000000000000003132 166.0
HFD3_k127_4210653_0 Ribonuclease E/G family K08301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004886 501.0
HFD3_k127_4210653_1 Penicillin binding protein transpeptidase domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 351.0
HFD3_k127_4210653_2 Belongs to the SEDS family K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 294.0
HFD3_k127_4211746_0 CotH kinase protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 589.0
HFD3_k127_4212806_0 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.0 1173.0
HFD3_k127_4212806_1 Protein-arginine kinase K19405 - 2.7.14.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 452.0
HFD3_k127_4212806_2 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000001264 200.0
HFD3_k127_4212806_3 PFAM UvrB UvrC protein K19411 - - 0.00000000000000000000000000000000000000000000000000003656 192.0
HFD3_k127_4226401_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 6.3e-235 746.0
HFD3_k127_4226401_1 Protein of unknown function (DUF1501) - - - 1.811e-225 706.0
HFD3_k127_4226401_2 PFAM Mandelate racemase muconate lactonizing enzyme, N-terminal domain protein K01684 - 4.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 600.0
HFD3_k127_4226401_3 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003044 552.0
HFD3_k127_4226401_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005421 544.0
HFD3_k127_4226401_5 Arginosuccinate synthase K01940 - 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008104 420.0
HFD3_k127_4226401_6 Methyltransferase domain K00598 - 2.1.1.144 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 304.0
HFD3_k127_4226401_7 DJ-1/PfpI family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004418 256.0
HFD3_k127_4226401_8 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000009835 216.0
HFD3_k127_4232215_0 'glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 509.0
HFD3_k127_4232215_1 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002942 372.0
HFD3_k127_4232215_2 Alpha amylase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 327.0
HFD3_k127_4252992_0 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003417 566.0
HFD3_k127_4252992_1 competence protein COMEC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007936 389.0
HFD3_k127_4252992_2 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000493 374.0
HFD3_k127_4252992_3 Anthranilate synthase component I, N terminal region K01657,K01665,K13950 - 2.6.1.85,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 376.0
HFD3_k127_4252992_4 Diacylglycerol kinase catalytic domain (presumed) - - - 0.0000000000000000000000000000000000000000000000000000000000000001523 233.0
HFD3_k127_4252992_5 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000282 215.0
HFD3_k127_4252992_6 Belongs to the UPF0102 family K07460 - - 0.0000000000000000004354 94.0
HFD3_k127_4252992_7 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000004525 83.0
HFD3_k127_4252992_8 Pilus assembly protein PilX - - - 0.000000000001441 81.0
HFD3_k127_4262909_0 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0 1627.0
HFD3_k127_4262909_1 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 441.0
HFD3_k127_4262909_2 Ribose/Galactose Isomerase - - - 0.0000000000000000000000000000000000000000000000000000000004913 206.0
HFD3_k127_4267364_0 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008712 566.0
HFD3_k127_4267364_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007888 507.0
HFD3_k127_4267364_2 Histidine biosynthesis protein HisG domain K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004359 406.0
HFD3_k127_4267364_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 306.0
HFD3_k127_4267364_4 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003708 276.0
HFD3_k127_4267364_5 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000001952 211.0
HFD3_k127_4267364_6 Uncharacterized conserved protein (DUF2203) - - - 0.00000000000000001682 96.0
HFD3_k127_4267364_7 alginic acid biosynthetic process K01729,K17713 - 4.2.2.3 0.0000000000006735 82.0
HFD3_k127_4267364_8 CHASE2 - - - 0.0000000000009302 82.0
HFD3_k127_4267364_9 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.0000005138 63.0
HFD3_k127_4297201_0 peptidyl-tyrosine sulfation - - - 1.08e-220 707.0
HFD3_k127_4297201_1 beta-propeller repeat - - - 0.000000000000000000000000004228 119.0
HFD3_k127_4309172_0 PFAM metallophosphoesterase K03547 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 338.0
HFD3_k127_4309172_1 SMC domain protein K03546 - - 0.0000000000000000000000000000000000000000000000000000000000003758 237.0
HFD3_k127_4309172_2 Immunoglobulin - - - 0.0000000000000000000000007243 120.0
HFD3_k127_4309172_3 CotH kinase protein - - - 0.0000000000000000000005252 111.0
HFD3_k127_4309172_4 PFAM sulfatase - - - 0.0001109 55.0
HFD3_k127_4317042_0 pyrroloquinoline quinone binding - - - 4.488e-235 764.0
HFD3_k127_4317042_1 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005038 393.0
HFD3_k127_4317042_2 CotH kinase protein - - - 0.00000000000000000000000000000000000000000000000000000000000000004797 244.0
HFD3_k127_4317042_3 DNA-templated transcription, initiation - - - 0.00000000000000000000000000000000000000000000000000000006679 204.0
HFD3_k127_4317042_4 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000008733 201.0
HFD3_k127_4317042_5 PFAM Blue (type 1) copper domain K09992 - - 0.0000000000000000000000000000000003968 137.0
HFD3_k127_4317042_6 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000001244 132.0
HFD3_k127_4317042_7 ATP-binding region ATPase domain protein - - - 0.00000000000000000000001749 106.0
HFD3_k127_4322457_0 COG1012 NAD-dependent aldehyde - - - 8.227e-198 652.0
HFD3_k127_4322457_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 462.0
HFD3_k127_4322457_2 Mandelate racemase muconate lactonizing enzyme K19802 - 5.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 359.0
HFD3_k127_4322457_3 Methane oxygenase PmoA - - - 0.00000000000000000000000000002511 130.0
HFD3_k127_4322457_4 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00001453 57.0
HFD3_k127_4335557_0 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000296 211.0
HFD3_k127_4335557_1 PFAM Proprotein convertase P-domain - - - 0.000000000000000000000000000000000000007817 170.0
HFD3_k127_4335557_2 Glucose / Sorbosone dehydrogenase - - - 0.0000000000006124 84.0
HFD3_k127_4335557_3 domain protein K01218,K10804,K20276 - 3.1.1.5,3.2.1.78 0.0000007398 64.0
HFD3_k127_4335557_4 Gliding motility protein - - - 0.00005984 58.0
HFD3_k127_435476_0 transmembrane transport - - - 0.000000000008372 76.0
HFD3_k127_435476_1 ABC-2 family transporter protein - - - 0.00004237 56.0
HFD3_k127_435476_2 ABC-2 family transporter protein K01992 - - 0.00007541 53.0
HFD3_k127_4366294_0 Dipeptidyl peptidase IV (DPP IV) - - - 4.461e-282 892.0
HFD3_k127_4366294_1 Protein of unknown function (DUF1501) - - - 4.756e-227 710.0
HFD3_k127_4366294_2 Protein of unknown function (DUF1501) - - - 1.027e-207 652.0
HFD3_k127_4366294_3 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006561 492.0
HFD3_k127_4366294_4 Proline racemase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003928 433.0
HFD3_k127_4366294_5 PFAM peptidyl-prolyl cis-trans isomerase cyclophilin type K03767 - 5.2.1.8 0.0000000000001321 70.0
HFD3_k127_4391412_0 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008662 580.0
HFD3_k127_4391412_1 phosphoglycerate mutase K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005022 401.0
HFD3_k127_4391412_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000619 370.0
HFD3_k127_4391412_3 Zn-dependent metallo-hydrolase RNA specificity domain K07577,K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004594 313.0
HFD3_k127_4391412_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008825 322.0
HFD3_k127_4391412_5 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001581 286.0
HFD3_k127_4391412_6 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000004308 240.0
HFD3_k127_4391412_7 cell redox homeostasis K03671,K07152 - - 0.00000000000000000000000000000000006123 148.0
HFD3_k127_4391412_8 Large extracellular alpha-helical protein K03088,K06894 - - 0.000000000008582 77.0
HFD3_k127_4395127_0 Spore coat protein CotH K01216,K07004 - 3.2.1.73 0.0000000004023 73.0
HFD3_k127_439817_0 E1-E2 ATPase - - - 6.144e-223 716.0
HFD3_k127_439817_1 Protein of unknown function (DUF3748) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007866 501.0
HFD3_k127_439817_2 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000003887 143.0
HFD3_k127_439817_3 Ribosomal protein L35 K02916 - - 0.00000000000001273 76.0
HFD3_k127_4412878_0 Protein of unknown function (DUF1549) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005403 615.0
HFD3_k127_4412878_1 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004585 589.0
HFD3_k127_4412878_2 ribosome binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007922 297.0
HFD3_k127_4419882_0 PA domain - - - 0.0 1214.0
HFD3_k127_4419882_1 peptidyl-tyrosine sulfation - - - 2.151e-201 638.0
HFD3_k127_4419882_2 LytTr DNA-binding domain K02477 - - 0.0000000000000000000000000000000000000000000000000000000000000002917 230.0
HFD3_k127_4419882_3 Rhomboid family K02441 - - 0.0000000000000000000000000000000000000000006072 169.0
HFD3_k127_4419882_4 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000000000000001776 134.0
HFD3_k127_4419882_5 PFAM Smr protein MutS2 - - - 0.0000000000000000000000000004797 120.0
HFD3_k127_4419882_6 calcium- and calmodulin-responsive adenylate cyclase activity K01186 - 3.2.1.18 0.000000000000000000000000008971 123.0
HFD3_k127_4462450_0 Planctomycete cytochrome C - - - 2.602e-308 968.0
HFD3_k127_4462450_1 Protein of unknown function (DUF1501) - - - 6.113e-254 791.0
HFD3_k127_4462450_2 Selenocysteine-specific translation elongation factor K03833 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001887 270.0
HFD3_k127_4462450_3 - - - - 0.00000000000000000000000000000000000000204 161.0
HFD3_k127_4462450_4 beta-fructofuranosidase activity - - - 0.0000000000000000000000000001493 117.0
HFD3_k127_4470031_0 Transport of potassium into the cell K03549 - - 6.895e-232 738.0
HFD3_k127_4470031_1 PFAM peptidase S8 and S53 subtilisin kexin sedolisin K08651 - 3.4.21.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006599 344.0
HFD3_k127_4474017_0 Tricorn protease homolog - - - 0.0 1303.0
HFD3_k127_4474017_1 UDP-glucoronosyl and UDP-glucosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005549 369.0
HFD3_k127_4474017_2 ABC-type sugar transport system periplasmic component K10439 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002272 283.0
HFD3_k127_4474017_3 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003504 283.0
HFD3_k127_4474017_5 Protein tyrosine phosphatase - - - 0.000000000000000000002191 100.0
HFD3_k127_4480927_0 protein histidine kinase activity K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000004996 259.0
HFD3_k127_4480927_1 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000005433 242.0
HFD3_k127_4480927_2 protein histidine kinase activity K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000856 188.0
HFD3_k127_4517088_0 KAP family P-loop domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001223 297.0
HFD3_k127_4517088_1 Lipopolysaccharide-assembly - - - 0.0000000000004885 78.0
HFD3_k127_4517088_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000003191 59.0
HFD3_k127_4547970_0 PFAM Conserved region in glutamate synthase K00284 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.7.1 0.0 1774.0
HFD3_k127_4547970_1 TIGRFAM glutamate synthases, NADH NADPH, small subunit K00266 - 1.4.1.13,1.4.1.14 1.609e-284 878.0
HFD3_k127_4559_0 cell wall binding repeat 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000172 283.0
HFD3_k127_4559_1 cellulose binding - - - 0.000000000000000000000000000000000000000000000000009773 204.0
HFD3_k127_4559_2 Peptidase C13 family K09607 - - 0.0000000000000000002419 104.0
HFD3_k127_4559_3 PFAM PKD domain containing protein - - - 0.00000002069 70.0
HFD3_k127_4559_4 domain, Protein - - - 0.00007767 58.0
HFD3_k127_4559_5 Chondroitinase B K01729 - 4.2.2.3 0.0001769 57.0
HFD3_k127_4575274_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1307.0
HFD3_k127_4575274_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004018 428.0
HFD3_k127_4575274_2 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 374.0
HFD3_k127_4575274_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03471 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 294.0
HFD3_k127_4575274_4 COG1194 A G-specific DNA glycosylase K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009723 268.0
HFD3_k127_4575274_6 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.0000000001142 68.0
HFD3_k127_4575274_7 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K12257 - - 0.0004352 49.0
HFD3_k127_4584577_0 beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 457.0
HFD3_k127_4584577_1 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000001753 218.0
HFD3_k127_4584577_2 Serine threonine phosphatase - - - 0.0000000000000000000000000002397 134.0
HFD3_k127_4584577_3 protein conserved in bacteria K09793 - - 0.00000000000000000000000001087 115.0
HFD3_k127_4584577_4 Beta-lactamase - - - 0.00000000000000000008232 91.0
HFD3_k127_4584577_5 Thermolysin metallopeptidase, alpha-helical domain K01400 - 3.4.24.28 0.00000000003293 78.0
HFD3_k127_4584577_6 Fibronectin type III domain - - - 0.0000000002986 74.0
HFD3_k127_4602322_0 Spore coat protein CotH K07093 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 448.0
HFD3_k127_460536_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004424 459.0
HFD3_k127_460536_1 Protein of unknown function (DUF1587) - - - 0.000000000000000000002146 97.0
HFD3_k127_4611481_0 dehydrogenases and related proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006215 293.0
HFD3_k127_4611481_1 isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000103 265.0
HFD3_k127_4611481_2 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000005306 184.0
HFD3_k127_4611481_3 Alkyl hydroperoxide reductase Thiol specific antioxidant K03564 - 1.11.1.15 0.0000000000000000000000000000000001093 141.0
HFD3_k127_4626780_0 ATPase activity K06027 - 3.6.4.6 6.77e-225 712.0
HFD3_k127_4626780_1 twitching motility protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 476.0
HFD3_k127_4626780_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000001691 252.0
HFD3_k127_4626780_3 6-phosphogluconolactonase K01057 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 3.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000001828 235.0
HFD3_k127_4626780_4 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000000000000000000001953 220.0
HFD3_k127_4626780_5 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.00000000000000000000000000000003178 138.0
HFD3_k127_4626780_6 M6 family metalloprotease domain protein - - - 0.0000003995 64.0
HFD3_k127_4626780_7 calcium- and calmodulin-responsive adenylate cyclase activity K00505,K01406,K07004 - 1.14.18.1,3.4.24.40 0.000003633 61.0
HFD3_k127_4628436_0 Protein of unknown function (DUF1501) - - - 1.544e-200 636.0
HFD3_k127_4628436_1 Membrane - - - 0.0000000000000000000000000004854 119.0
HFD3_k127_4628436_2 beta-N-acetylglucosaminidase K01197 - 3.2.1.35 0.00006381 46.0
HFD3_k127_4629177_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 1.064e-269 847.0
HFD3_k127_4629177_1 helicase superfamily c-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 586.0
HFD3_k127_4629177_2 DNA-templated transcription, initiation - - - 0.0000000000000000000000000000000000227 145.0
HFD3_k127_4639471_0 Protein of unknown function DUF116 - - - 1.719e-275 858.0
HFD3_k127_4639471_1 Protein kinase domain - - - 5.983e-214 707.0
HFD3_k127_4639471_2 DNA-templated transcription, initiation - - - 0.00000000000000000000000000000000000000000000000000000000006984 216.0
HFD3_k127_4642700_0 response to antibiotic - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 454.0
HFD3_k127_4674465_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 513.0
HFD3_k127_4674465_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 300.0
HFD3_k127_4674465_2 Aminotransferase class-V - - - 0.0000000000000000000000000000000001089 136.0
HFD3_k127_4674465_3 - - - - 0.0001385 46.0
HFD3_k127_4679357_0 Beta-L-arabinofuranosidase, GH127 - - - 4.215e-273 863.0
HFD3_k127_4679357_1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 443.0
HFD3_k127_4679357_2 Xylose isomerase-like TIM barrel K03079 - 5.1.3.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 406.0
HFD3_k127_4690588_0 CARDB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 636.0
HFD3_k127_4690588_1 - - - - 0.00002122 60.0
HFD3_k127_4699913_0 lipolytic protein G-D-S-L family - - - 2.05e-282 924.0
HFD3_k127_4699913_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 3.959e-207 660.0
HFD3_k127_4699913_2 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 541.0
HFD3_k127_4699913_3 Calcineurin-like phosphoesterase superfamily domain K21814 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008104 291.0
HFD3_k127_4699913_4 - - - - 0.00000009512 63.0
HFD3_k127_4735770_0 pyrroloquinoline quinone binding - - - 1.441e-313 992.0
HFD3_k127_4735770_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 593.0
HFD3_k127_4735770_2 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 464.0
HFD3_k127_4735770_3 iron ion homeostasis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002857 275.0
HFD3_k127_4745213_0 Thiamine pyrophosphate enzyme, central domain - - - 1.756e-237 745.0
HFD3_k127_4745213_1 Predicted membrane protein (DUF2339) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000801 527.0
HFD3_k127_4745213_2 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 454.0
HFD3_k127_4745213_3 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 356.0
HFD3_k127_4745213_4 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03188 - - 0.000267 51.0
HFD3_k127_4752796_0 Protein of unknown function (DUF1549) - - - 0.0 1036.0
HFD3_k127_4752796_1 WD-40 repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005451 386.0
HFD3_k127_4752796_2 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000152 259.0
HFD3_k127_4777432_0 Spore coat protein CotH K01216,K07004 - 3.2.1.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008468 324.0
HFD3_k127_4777432_1 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000004314 165.0
HFD3_k127_4802852_0 PFAM WD domain, G-beta repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000424 394.0
HFD3_k127_4802852_1 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005532 291.0
HFD3_k127_4802852_2 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000000000005784 188.0
HFD3_k127_4802852_3 Pkd domain containing protein - - - 0.0000000000000002565 95.0
HFD3_k127_4802852_4 Purple acid Phosphatase, N-terminal domain - - - 0.00003191 59.0
HFD3_k127_4814641_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 460.0
HFD3_k127_4814641_1 PFAM Uncharacterised BCR, COG1649 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 404.0
HFD3_k127_4814641_2 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000002252 185.0
HFD3_k127_4814641_3 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.00000000000000000000003942 101.0
HFD3_k127_4816905_0 Glycosyltransferase like family 2 K07011 - - 0.0000000000000000000000000000000000000000000000000000000000001096 224.0
HFD3_k127_4816905_1 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000006774 221.0
HFD3_k127_4816905_2 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000002813 225.0
HFD3_k127_4816905_3 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000001133 203.0
HFD3_k127_4816905_4 FemAB family - - - 0.00000000000000000000000000000000000000000000000000007179 207.0
HFD3_k127_4816905_5 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000001667 185.0
HFD3_k127_4831141_0 COG3119 Arylsulfatase A and related enzymes K01130 - 3.1.6.1 1.451e-214 677.0
HFD3_k127_4831141_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007146 422.0
HFD3_k127_4831141_2 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004828 295.0
HFD3_k127_4831141_3 Spore coat protein CotH - - - 0.000000000000000000000000000000000008423 154.0
HFD3_k127_4831141_4 Hep Hag repeat protein K07093 - - 0.00000000000000000000001331 118.0
HFD3_k127_4831141_5 cellulase activity K00428,K11005 - 1.11.1.5 0.00000000003198 77.0
HFD3_k127_4831141_6 peptidase - - - 0.0000001269 65.0
HFD3_k127_4831141_7 COG3209 Rhs family protein - - - 0.0000001905 64.0
HFD3_k127_4857646_0 Spore coat protein CotH K01216,K07004 - 3.2.1.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 583.0
HFD3_k127_4857646_1 Fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 487.0
HFD3_k127_4857646_2 CotH kinase protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002831 302.0
HFD3_k127_4857646_3 Spore coat protein CotH K01216,K07004 - 3.2.1.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000004571 292.0
HFD3_k127_4857646_4 MraW methylase family - - - 0.00000000000000000000000000000000000000000000000000008295 190.0
HFD3_k127_4857646_5 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000002003 181.0
HFD3_k127_4857646_6 candidate b-glycosidase, glycoside hydrolase family 8 protein - - - 0.0000000000000000004034 104.0
HFD3_k127_4857646_7 pilus organization K02305 - - 0.0000000000000001726 91.0
HFD3_k127_489959_0 CotH kinase protein - - - 2.882e-199 674.0
HFD3_k127_489959_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000001195 250.0
HFD3_k127_489959_2 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000005215 114.0
HFD3_k127_489959_3 Spore coat protein CotH K01216,K07004 - 3.2.1.73 0.0000000000001196 86.0
HFD3_k127_4906848_0 Mitochondrial biogenesis AIM24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007311 427.0
HFD3_k127_4906848_1 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000002066 186.0
HFD3_k127_4920049_0 Spore coat protein CotH K01216,K07004 - 3.2.1.73 0.0 1367.0
HFD3_k127_4920049_1 Erythromycin esterase - - - 0.000000000003707 82.0
HFD3_k127_4925774_0 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 510.0
HFD3_k127_4925774_1 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007233 461.0
HFD3_k127_4925774_2 hydroxyacid-oxoacid transhydrogenase activity K00001,K01714 - 1.1.1.1,4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004434 447.0
HFD3_k127_4925774_3 Component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 361.0
HFD3_k127_4925774_4 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000004602 220.0
HFD3_k127_4925774_5 Antibiotic biosynthesis monooxygenase K11530 - 5.3.1.32 0.000000000000000000000000000000000000000004493 156.0
HFD3_k127_4928596_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 2.352e-202 638.0
HFD3_k127_4928596_1 PFAM Uracil-DNA glycosylase superfamily K10800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 329.0
HFD3_k127_4929235_0 Penicillin binding protein transpeptidase domain K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 367.0
HFD3_k127_4929235_1 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 349.0
HFD3_k127_4929235_2 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0003847 46.0
HFD3_k127_4945035_0 Acetyl xylan esterase (AXE1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 459.0
HFD3_k127_4945035_1 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 322.0
HFD3_k127_4945035_2 dehalogenase, type II K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000001165 199.0
HFD3_k127_4945035_3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.00000000000000000000000000000000003391 137.0
HFD3_k127_4945035_4 carboxylic ester hydrolase activity - - - 0.0001692 53.0
HFD3_k127_4948594_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1158.0
HFD3_k127_4948594_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 443.0
HFD3_k127_4948594_2 PFAM Biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.0000002742 64.0
HFD3_k127_4982528_0 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 0.0 1566.0
HFD3_k127_4982528_1 Glutaminase - - - 7.443e-242 764.0
HFD3_k127_4982528_2 SMART Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 314.0
HFD3_k127_4982528_3 COG2931 RTX toxins and related Ca2 -binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001297 287.0
HFD3_k127_4982528_4 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000008245 262.0
HFD3_k127_4982528_5 cellulose binding - - - 0.00000000000000000000000000000002391 148.0
HFD3_k127_4982528_6 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000005637 104.0
HFD3_k127_4982528_7 cyclic nucleotide binding K10914 - - 0.000000000000009605 85.0
HFD3_k127_4982528_8 RHS Repeat - - - 0.00000000005623 78.0
HFD3_k127_4982528_9 amine dehydrogenase activity - - - 0.000000007904 70.0
HFD3_k127_4996531_0 beta-galactosidase activity K01190,K12308 - 3.2.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000903 563.0
HFD3_k127_4996531_1 SMART Pyrrolo-quinoline quinone K17713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 351.0
HFD3_k127_4996531_2 Domain of unknown function (DUF4838) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 321.0
HFD3_k127_4996531_3 Domain of unknown function (DUF4091) - - - 0.000000000000000000000000000000000000000000000000000000000006927 216.0
HFD3_k127_4996531_4 Carbohydrate family 9 binding domain-like - - - 0.0000000000000000000000000000000000000005375 171.0
HFD3_k127_4999279_0 nuclear chromosome segregation - - - 4.162e-214 711.0
HFD3_k127_4999279_1 EVE domain - - - 0.000000000000000000000000000000000000000000008903 168.0
HFD3_k127_4999279_2 HAD-hyrolase-like - - - 0.000000000000000000000000000000001998 139.0
HFD3_k127_5006550_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1269.0
HFD3_k127_5006550_1 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006653 425.0
HFD3_k127_5006550_2 Outer membrane efflux protein K15725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 370.0
HFD3_k127_5006550_3 thymidine phosphorylase activity K00758 GO:0000002,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006725,GO:0006807,GO:0006935,GO:0006996,GO:0007005,GO:0007275,GO:0008150,GO:0008152,GO:0008655,GO:0009032,GO:0009056,GO:0009058,GO:0009116,GO:0009163,GO:0009164,GO:0009605,GO:0009653,GO:0009887,GO:0009987,GO:0010646,GO:0016043,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0018130,GO:0019438,GO:0019439,GO:0023051,GO:0031641,GO:0031644,GO:0032501,GO:0032502,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0040011,GO:0042221,GO:0042330,GO:0042802,GO:0042803,GO:0043094,GO:0043097,GO:0043174,GO:0044057,GO:0044058,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046134,GO:0046135,GO:0046483,GO:0046700,GO:0046983,GO:0048513,GO:0048731,GO:0048856,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051239,GO:0051960,GO:0051969,GO:0055086,GO:0065007,GO:0071704,GO:0071840,GO:0072527,GO:0072528,GO:0072529,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659,GO:1905333,GO:2000026 2.4.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003913 367.0
HFD3_k127_5006550_4 DNA methylase K00571 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000957 332.0
HFD3_k127_5006550_5 Na channel or K07150 - - 0.000000000000000000000000000000000000000006383 166.0
HFD3_k127_5006550_6 - - - - 0.0000000000000000000000000000005408 136.0
HFD3_k127_5006550_7 - - - - 0.000000000000000000000002325 118.0
HFD3_k127_5006550_8 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000004599 96.0
HFD3_k127_5006550_9 - - - - 0.00000000005575 74.0
HFD3_k127_5009500_0 PFAM TonB-dependent Receptor Plug - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 422.0
HFD3_k127_5009500_1 Two component regulator propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 386.0
HFD3_k127_5009500_2 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 364.0
HFD3_k127_5009500_3 Phosphotriesterase family K07048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008185 340.0
HFD3_k127_5009500_4 MotA/TolQ/ExbB proton channel family K03562 - - 0.000000000000000000000000000000000000000000000006282 186.0
HFD3_k127_5009500_5 PFAM Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000005507 153.0
HFD3_k127_5009500_6 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.0000000000000001468 85.0
HFD3_k127_5009500_7 Cupin domain - - - 0.0000000000006275 79.0
HFD3_k127_5009500_8 Pkd domain containing protein - - - 0.000004442 53.0
HFD3_k127_5014221_0 DEAD DEAH box helicase - - - 0.0 1260.0
HFD3_k127_5014221_1 beta-N-acetylhexosaminidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 578.0
HFD3_k127_5014221_3 polygalacturonase activity - - - 0.00000000003721 76.0
HFD3_k127_5022158_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0 1077.0
HFD3_k127_5022158_1 Utp--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 364.0
HFD3_k127_5022158_2 extracellular matrix structural constituent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001423 294.0
HFD3_k127_5022158_3 lyase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000004671 256.0
HFD3_k127_5031414_0 PFAM PBS lyase HEAT domain protein - - - 1.814e-289 918.0
HFD3_k127_5031414_1 peptidase - - - 0.0000000000000000000000000000000000000000000000000000000008317 211.0
HFD3_k127_5048809_0 transport - - - 0.00003956 55.0
HFD3_k127_5051480_0 His Kinase A (phosphoacceptor) domain - - - 1.913e-204 668.0
HFD3_k127_5051480_1 intramolecular transferase activity, transferring amino groups K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 561.0
HFD3_k127_5051480_10 Altronate dehydratase K01685,K01708 - 4.2.1.42,4.2.1.7 0.00000000000000000009941 99.0
HFD3_k127_5051480_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 529.0
HFD3_k127_5051480_3 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005056 358.0
HFD3_k127_5051480_4 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007421 356.0
HFD3_k127_5051480_5 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 306.0
HFD3_k127_5051480_6 PFAM membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 313.0
HFD3_k127_5051480_7 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.0000000000000000000000000000000000000000000000001226 181.0
HFD3_k127_5051480_8 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000005449 135.0
HFD3_k127_5051480_9 - - - - 0.0000000000000000000003622 107.0
HFD3_k127_5058242_0 GDSL-like Lipase/Acylhydrolase - - - 2.397e-204 651.0
HFD3_k127_5058242_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 444.0
HFD3_k127_5058242_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000728 426.0
HFD3_k127_5058242_3 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 306.0
HFD3_k127_5058242_4 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005265 286.0
HFD3_k127_5058242_5 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000008545 210.0
HFD3_k127_5058242_6 selenocysteine insertion sequence binding K03833 GO:0000049,GO:0000166,GO:0001514,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006412,GO:0006414,GO:0006417,GO:0006451,GO:0006518,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009069,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016259,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034248,GO:0034641,GO:0034645,GO:0035368,GO:0035639,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:2000112 - 0.00000000000000000000000000000000000000000001965 176.0
HFD3_k127_5058242_7 Aldo/keto reductase family - - - 0.0000000000000000000000000007893 116.0
HFD3_k127_5058242_8 structural constituent of ribosome K02911 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000006509 76.0
HFD3_k127_5058242_9 metal-binding, possibly nucleic acid-binding protein K07040 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.00000000002171 71.0
HFD3_k127_5058997_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 2.065e-207 674.0
HFD3_k127_5058997_1 NMT1-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 608.0
HFD3_k127_5058997_2 DMSO reductase anchor subunit (DmsC) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 437.0
HFD3_k127_5058997_3 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006188 388.0
HFD3_k127_5058997_4 ABC transporter K02049,K15578,K15579 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008439 380.0
HFD3_k127_5058997_5 Binding-protein-dependent transport system inner membrane component K15577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 374.0
HFD3_k127_5058997_6 Dehydratase family K22396 - 4.2.1.82 0.0000000000000000000004504 96.0
HFD3_k127_5065532_0 Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000000000000000004912 226.0
HFD3_k127_5065532_1 general secretion pathway protein K02456 - - 0.000000000004908 77.0
HFD3_k127_5065532_2 lymphoid tissue lymphoma translocation K07369 - - 0.0000001794 64.0
HFD3_k127_5095975_0 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 469.0
HFD3_k127_5095975_1 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 453.0
HFD3_k127_5095975_2 Forkhead associated domain - - - 0.0000000000000001752 85.0
HFD3_k127_5100382_0 Involved in the tonB-independent uptake of proteins - - - 0.0 1232.0
HFD3_k127_5100382_1 PHP domain protein - - - 3.726e-214 696.0
HFD3_k127_5100382_2 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 377.0
HFD3_k127_5100382_3 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007621 353.0
HFD3_k127_5100382_4 DNA-templated transcription, initiation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005177 271.0
HFD3_k127_5100382_5 COGs COG4299 conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001203 257.0
HFD3_k127_5107928_0 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000457 446.0
HFD3_k127_5107928_1 Macrocin-O-methyltransferase (TylF) K05303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 358.0
HFD3_k127_5107928_2 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000005898 195.0
HFD3_k127_5107928_3 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000007251 180.0
HFD3_k127_5107928_4 Heparinase II/III N-terminus - - - 0.000000000000000000000000000000000000006632 164.0
HFD3_k127_5107928_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000003091 124.0
HFD3_k127_5107928_6 Glycosyl transferases group 1 - - - 0.0000000000000000000001049 113.0
HFD3_k127_5107928_7 Acetyltransferase (Isoleucine patch superfamily) - - - 0.00000000000022 82.0
HFD3_k127_5107928_8 - - - - 0.0000000008641 71.0
HFD3_k127_511546_0 RHS Repeat - - - 0.00000000000000000000000000000000002193 156.0
HFD3_k127_511546_1 PFAM 3-carboxy-cis,cis-muconate lactonizing enzyme K01317 - 3.4.21.10 0.000000000000001801 91.0
HFD3_k127_5120440_0 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 441.0
HFD3_k127_5120440_1 glucuronate isomerase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 375.0
HFD3_k127_5120440_3 cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides K00681 - 2.3.2.2,3.4.19.13 0.00000000000006836 74.0
HFD3_k127_514631_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 4.109e-244 767.0
HFD3_k127_514631_1 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 436.0
HFD3_k127_514631_2 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 303.0
HFD3_k127_514631_3 TIGRFAM autotransporter-associated beta strand repeat protein - - - 0.00000000000000000000000000000000000000000004841 184.0
HFD3_k127_5167106_0 Protein of unknown function (DUF4255) - - - 0.000000000000000000000000000000000000000000000000007847 189.0
HFD3_k127_5167106_1 CotH kinase protein - - - 0.000000000000000000000000000000000000000004969 179.0
HFD3_k127_5167106_2 Spore coat protein CotH - - - 0.0000000000000000000000000000002508 144.0
HFD3_k127_5167106_3 Transcription factor zinc-finger K09981 - - 0.0000000000000000000002948 102.0
HFD3_k127_5167106_4 Fibrinogen-related domains (FReDs) - - - 0.00000000000000006114 96.0
HFD3_k127_5167106_6 Parallel beta-helix repeats - - - 0.00000007621 66.0
HFD3_k127_5167106_7 - - - - 0.0002926 46.0
HFD3_k127_5180104_0 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004288 577.0
HFD3_k127_5180104_1 PHP domain protein K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 445.0
HFD3_k127_5180104_2 glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000004033 226.0
HFD3_k127_5182214_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate K03701 - - 6.741e-235 741.0
HFD3_k127_5184937_0 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 454.0
HFD3_k127_5184937_1 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000141 267.0
HFD3_k127_5184937_2 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000001813 194.0
HFD3_k127_5184937_3 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000564 121.0
HFD3_k127_5191396_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1167.0
HFD3_k127_5191396_1 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006151 295.0
HFD3_k127_5191396_2 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000006731 205.0
HFD3_k127_5191396_3 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000005451 186.0
HFD3_k127_5191396_4 DNA / pantothenate metabolism flavoprotein K21977 - 6.3.2.5 0.000000000000000000000000000000000000000008769 171.0
HFD3_k127_5191396_5 Sigma-70, region 4 - - - 0.00000000000000000000000000000000000000001823 170.0
HFD3_k127_5191396_6 - - - - 0.00000002344 64.0
HFD3_k127_5197539_0 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 318.0
HFD3_k127_5197539_1 Glycosyltransferase WbsX - - - 0.0000000000000000000000000000000000000000007032 171.0
HFD3_k127_5198342_0 CotH kinase protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002354 282.0
HFD3_k127_5198342_1 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000005022 227.0
HFD3_k127_5205596_0 Protein of unknown function (DUF1552) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 539.0
HFD3_k127_5205596_1 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008769 293.0
HFD3_k127_5205596_2 His Kinase A (phosphoacceptor) domain K20973 - 2.7.13.3 0.00000000000000000000000000000003631 131.0
HFD3_k127_5205596_3 peptidyl-tyrosine sulfation - - - 0.00000000000000000002079 98.0
HFD3_k127_5215364_0 PFAM UvrD REP helicase K03656,K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005342 531.0
HFD3_k127_5215364_1 GDSL-like Lipase/Acylhydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000001485 237.0
HFD3_k127_5230242_0 Sulfatase-modifying factor enzyme 1 - - - 1.316e-249 797.0
HFD3_k127_5230242_1 RDD family - - - 0.00000000000000000000000000002342 130.0
HFD3_k127_5230242_2 Carbohydrate esterase, sialic acid-specific acetylesterase - - - 0.0000000004182 72.0
HFD3_k127_5230242_3 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.000000006634 59.0
HFD3_k127_5230242_4 Right handed beta helix region - - - 0.000466 53.0
HFD3_k127_5240548_0 Glucose / Sorbosone dehydrogenase K00428,K01083,K01728 - 1.11.1.5,3.1.3.8,4.2.2.2 0.0000000000000000000000001828 125.0
HFD3_k127_5240548_1 Belongs to the glycosyl hydrolase family 6 K05988,K06882 - 3.2.1.11 0.0000000002683 75.0
HFD3_k127_5240548_2 Immunoglobulin - - - 0.000003068 62.0
HFD3_k127_525218_0 arginine decarboxylase K01585 - 4.1.1.19 1.3e-202 640.0
HFD3_k127_525218_1 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) K06169 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005735 271.0
HFD3_k127_525218_2 Prokaryotic N-terminal methylation motif - - - 0.00000000000000002269 91.0
HFD3_k127_5296867_0 D-isomer specific 2-hydroxyacid dehydrogenase catalytic region K00018 - 1.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 408.0
HFD3_k127_5296867_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006873 377.0
HFD3_k127_5296867_2 Belongs to the GPI family K01810 - 5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 300.0
HFD3_k127_5313865_0 Tryptophan halogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006961 610.0
HFD3_k127_5313865_1 biotin synthase activity K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 329.0
HFD3_k127_5313865_2 CotH kinase protein - - - 0.00000000000000000000000000000000000000000000000000000000007812 235.0
HFD3_k127_5313865_3 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000000000001317 119.0
HFD3_k127_5313865_4 Prokaryotic dksA/traR C4-type zinc finger - - - 0.0000000000000000001673 97.0
HFD3_k127_5313865_5 Glucose / Sorbosone dehydrogenase - - - 0.000000000006762 80.0
HFD3_k127_531449_0 oligopeptide transport K03305 - - 1.984e-258 804.0
HFD3_k127_531449_1 thiolester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004254 318.0
HFD3_k127_5318237_0 Protein of unknown function (DUF1501) - - - 6.775e-250 778.0
HFD3_k127_5318237_1 Planctomycete cytochrome C - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005819 492.0
HFD3_k127_5318237_2 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 388.0
HFD3_k127_5318237_3 Zinc-uptake complex component A periplasmic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000025 280.0
HFD3_k127_5318237_4 PFAM Carbohydrate-selective porin OprB K07267 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004477 259.0
HFD3_k127_5318237_5 Iron dependent repressor, metal binding and dimerisation domain - - - 0.0000000000000000000000000000000007867 139.0
HFD3_k127_5322386_0 Pectate lyase K01728 - 4.2.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005794 368.0
HFD3_k127_5322386_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000005525 281.0
HFD3_k127_5322386_2 lipolytic protein G-D-S-L family K00612 - - 0.000000000000000000000000000000000000000000000000000000000000000000001918 258.0
HFD3_k127_5322386_3 Trehalose utilisation - - - 0.00000000000000000000000000000000000000000000000000000000000002446 224.0
HFD3_k127_5322386_4 Carbohydrate esterase, sialic acid-specific acetylesterase - - - 0.0000000000000000000000000000000000000000000000000000000007019 207.0
HFD3_k127_5322386_5 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000007186 166.0
HFD3_k127_5351027_0 CARDB - - - 3.216e-221 776.0
HFD3_k127_5351027_1 Coagulation factor 5/8 C-terminal domain, discoidin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 359.0
HFD3_k127_5352431_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 4.221e-209 655.0
HFD3_k127_5352431_1 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000486 394.0
HFD3_k127_5352431_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 385.0
HFD3_k127_5352431_3 - - - - 0.00000000000000000000000000000000000000000000001026 180.0
HFD3_k127_5352431_4 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000002162 144.0
HFD3_k127_5352431_5 Protein of unknown function (DUF971) K03593 - - 0.00000000000000000000000000001042 120.0
HFD3_k127_535276_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1222.0
HFD3_k127_535276_1 COG3119 Arylsulfatase A - - - 5.769e-254 792.0
HFD3_k127_535276_10 phosphate transporter K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008722 353.0
HFD3_k127_535276_11 lipoprotein transporter activity K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003804 309.0
HFD3_k127_535276_12 TIGRFAM phosphate binding protein K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 308.0
HFD3_k127_535276_13 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002501 292.0
HFD3_k127_535276_14 Tfp pilus assembly protein FimV - - - 0.00000000000000000000000000000000000000000000000000000000000000001927 244.0
HFD3_k127_535276_15 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000002964 231.0
HFD3_k127_535276_16 Inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000002837 227.0
HFD3_k127_535276_17 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000003356 223.0
HFD3_k127_535276_18 Protein of unknown function DUF47 - - - 0.0000000000000000000000000000000000000000000000000000000001342 210.0
HFD3_k127_535276_19 Protein of unknown function DUF47 - - - 0.00000000000000000000000000000000000000000000000000002043 196.0
HFD3_k127_535276_2 LeuA allosteric (dimerisation) domain K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 526.0
HFD3_k127_535276_20 Pit accessory protein K07220 - - 0.000000000000000000000000000000000000000000000000004903 188.0
HFD3_k127_535276_21 PFAM Mammalian cell entry related domain protein K02067 - - 0.0000000000000000000000000000000000000000000000003262 188.0
HFD3_k127_535276_22 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000006753 192.0
HFD3_k127_535276_23 PFAM Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000000000149 177.0
HFD3_k127_535276_24 negative regulation of phosphate transmembrane transport K01104,K02039,K03741 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 1.20.4.1,3.1.3.48 0.00000000000000000000000000000000000000008793 165.0
HFD3_k127_535276_25 enterobactin catabolic process - - - 0.0000000000000000000000000000000000004081 153.0
HFD3_k127_535276_26 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000002063 136.0
HFD3_k127_535276_27 - - - - 0.000000000000000000000005857 104.0
HFD3_k127_535276_3 phosphate transporter K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002971 422.0
HFD3_k127_535276_4 TIGRFAM phosphate ABC transporter, inner membrane subunit PstA K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 415.0
HFD3_k127_535276_5 TIGRFAM phosphate ABC transporter, inner membrane subunit PstC K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005443 398.0
HFD3_k127_535276_6 Binding-protein-dependent transport system inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006009 391.0
HFD3_k127_535276_7 ATPase-coupled phosphate ion transmembrane transporter activity K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000999 375.0
HFD3_k127_535276_8 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 374.0
HFD3_k127_535276_9 phosphorelay signal transduction system K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008565 358.0
HFD3_k127_5360227_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006937 372.0
HFD3_k127_5360227_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004858 320.0
HFD3_k127_5360227_2 peptidase activity - - - 0.00000000000000000000000000000000000000000000000000004625 213.0
HFD3_k127_5360227_3 TIGRFAM glutamate synthases, NADH NADPH, small subunit K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000007847 85.0
HFD3_k127_537285_0 response to heat K03694,K03696 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 355.0
HFD3_k127_5393830_0 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006793 545.0
HFD3_k127_5393830_1 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005778 456.0
HFD3_k127_5393830_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 379.0
HFD3_k127_5393830_3 ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062 334.0
HFD3_k127_5393830_4 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000702 318.0
HFD3_k127_5412071_0 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002843 366.0
HFD3_k127_5412071_1 WD-40 repeat - - - 0.00000000000000000000000000000000000000000002786 186.0
HFD3_k127_5435_0 von Willebrand factor, type A - - - 5.811e-194 628.0
HFD3_k127_5435_1 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008386 639.0
HFD3_k127_5435_2 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004327 544.0
HFD3_k127_5435_3 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 495.0
HFD3_k127_5435_4 PFAM S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 500.0
HFD3_k127_5435_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009409 321.0
HFD3_k127_5435_6 typically periplasmic contain C-terminal PDZ domain K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000009094 276.0
HFD3_k127_5440548_0 PFAM oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005432 443.0
HFD3_k127_5440548_1 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 400.0
HFD3_k127_5440548_11 Protein of unknown function (DUF1501) - - - 0.0000017 50.0
HFD3_k127_5440548_2 PFAM UBA THIF-type NAD FAD binding protein K22132 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000011 287.0
HFD3_k127_5440548_3 PFAM TatD-related deoxyribonuclease K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002741 283.0
HFD3_k127_5440548_4 DNA-templated transcription, initiation - - - 0.000000000000000000000000000000000000000000000000000000000000000001118 235.0
HFD3_k127_5440548_5 N-6 DNA methylase K03427 - 2.1.1.72 0.000000000000000000000000000000000000000000001919 165.0
HFD3_k127_5440548_6 Fe-S metabolism K02426 - - 0.00000000000000000000000000000001647 134.0
HFD3_k127_5440548_7 - - - - 0.00000000000000000000000000008729 123.0
HFD3_k127_5440548_8 GIY-YIG catalytic domain - - - 0.000000000000000000000002097 107.0
HFD3_k127_5440548_9 Alpha-tubulin suppressor and related RCC1 domain-containing - - - 0.000000001139 66.0
HFD3_k127_5453227_0 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 4.802e-245 779.0
HFD3_k127_5453227_1 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 604.0
HFD3_k127_5453227_2 Ankyrin repeats (many copies) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 431.0
HFD3_k127_5453227_3 Cadherin repeats. - - - 0.00000000000000000000000000003344 132.0
HFD3_k127_5456860_0 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 446.0
HFD3_k127_5456860_1 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 410.0
HFD3_k127_5456860_2 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 406.0
HFD3_k127_5456860_3 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K02056,K05776,K10441,K10539,K10542,K10545,K10548 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000654 359.0
HFD3_k127_5462399_0 Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 294.0
HFD3_k127_5462399_1 DNA-templated transcription, initiation - - - 0.0000000000000000000000000000000000000000000000000000000000008575 218.0
HFD3_k127_5462399_2 DNA-templated transcription, initiation - - - 0.000000000000000000000000000000000000000000000000000009329 198.0
HFD3_k127_5462399_3 Esterase-like activity of phytase - - - 0.0000000000000000000000000000000000000000001817 175.0
HFD3_k127_5462399_4 Belongs to the glycosyl hydrolase 2 family - - - 0.000000000000002104 90.0
HFD3_k127_5462399_5 general secretion pathway protein K02456 - - 0.000000000000007073 87.0
HFD3_k127_5462399_6 Collagen triple helix repeat (20 copies) - - - 0.00000008442 65.0
HFD3_k127_5500384_0 ABC transporter K06147,K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005028 328.0
HFD3_k127_5500384_1 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007919 259.0
HFD3_k127_5500384_2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000001068 222.0
HFD3_k127_5500384_3 Planctomycete cytochrome C - - - 0.0000000000000000000000000007172 132.0
HFD3_k127_5500384_4 Polysaccharide lyase family 4, domain II - - - 0.000000000000000000000000001596 125.0
HFD3_k127_5509586_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 459.0
HFD3_k127_5509586_1 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD K03581 - 3.1.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 431.0
HFD3_k127_5509586_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000000000000004584 204.0
HFD3_k127_5509586_3 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000433 150.0
HFD3_k127_5509586_4 Methionine biosynthesis protein MetW - - - 0.000000000000000000001319 106.0
HFD3_k127_5509586_5 - - - - 0.0000000000000000006648 93.0
HFD3_k127_5519747_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 405.0
HFD3_k127_5519747_1 Spore coat protein CotH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 397.0
HFD3_k127_5519747_2 CotH kinase protein - - - 0.000000000000000000000000000000000000000000000000000000001731 232.0
HFD3_k127_5519747_3 RNA pseudouridylate synthase K06178 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000039 210.0
HFD3_k127_5519747_4 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000007497 178.0
HFD3_k127_5519747_5 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000235 156.0
HFD3_k127_5519747_6 Pfam Polysaccharide lyase family 8, super-sandwich domain K08961 - 4.2.2.20,4.2.2.21 0.000000000000000000000000000000001272 153.0
HFD3_k127_5519747_7 pathogenesis K01337,K20276,K21449 - 3.4.21.50 0.00000000000000000006582 108.0
HFD3_k127_5519747_8 - - - - 0.000000000000001237 77.0
HFD3_k127_5521385_0 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008475 532.0
HFD3_k127_5521385_1 Abc transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 437.0
HFD3_k127_5521385_10 Poly(3-hydroxybutyrate) depolymerase K03932 - - 0.000000000000000001413 102.0
HFD3_k127_5521385_11 oxidoreductase activity - - - 0.00000000000000000423 101.0
HFD3_k127_5521385_12 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.0000000000002182 73.0
HFD3_k127_5521385_13 leucine- rich repeat protein - - - 0.0001325 56.0
HFD3_k127_5521385_2 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 391.0
HFD3_k127_5521385_3 PFAM Xylose isomerase domain protein TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001108 278.0
HFD3_k127_5521385_4 HlyD family K01993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000282 271.0
HFD3_k127_5521385_5 F5/8 type C domain - - - 0.0000000000000000000000000000000000001797 165.0
HFD3_k127_5521385_6 Putative adhesin - - - 0.0000000000000000000000000000000001383 145.0
HFD3_k127_5521385_7 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000000004608 127.0
HFD3_k127_5521385_8 Esterase PHB depolymerase K03932 - - 0.00000000000000000000004064 117.0
HFD3_k127_5521385_9 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000001069 103.0
HFD3_k127_5529268_0 PFAM peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 368.0
HFD3_k127_5529268_1 candidate b-glycosidase, glycoside hydrolase family 8 protein - - - 0.000000000000000000000000000001996 126.0
HFD3_k127_5529268_2 Domain of unknown function (DUF4082) - - - 0.00000000000000000004566 105.0
HFD3_k127_5529268_3 Bacterial PH domain - - - 0.00008226 45.0
HFD3_k127_5529270_0 PFAM Uncharacterised BCR, COG1649 - - - 1.047e-214 676.0
HFD3_k127_5529270_1 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007849 524.0
HFD3_k127_5543307_0 Spore coat protein CotH K01216,K07004 - 3.2.1.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 593.0
HFD3_k127_5543307_1 Regulator of chromosome condensation (RCC1) repeat - - - 0.0000000000000000000000000000000005195 154.0
HFD3_k127_5543469_0 Peptidase family M3 K08602 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001788 248.0
HFD3_k127_5543469_1 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.0000000000000000000000000000000000000000000000002355 181.0
HFD3_k127_5543469_2 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000002457 179.0
HFD3_k127_5543469_3 AP2 domain - - - 0.0002688 48.0
HFD3_k127_5548729_0 Cell wall formation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009601 608.0
HFD3_k127_5548729_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004984 381.0
HFD3_k127_5548729_2 D-ala D-ala ligase N-terminus K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003604 280.0
HFD3_k127_5548729_3 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000008748 98.0
HFD3_k127_5548729_4 Cell division protein FtsQ K03589 - - 0.0000004356 61.0
HFD3_k127_5557005_0 TIGRFAM Por secretion system C-terminal sorting domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003134 346.0
HFD3_k127_5557005_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001051 244.0
HFD3_k127_5557005_2 Serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000001293 213.0
HFD3_k127_5557005_3 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000004703 166.0
HFD3_k127_5557005_4 heme-binding domain, Pirellula Verrucomicrobium type - - - 0.00000000000000000000000000006732 134.0
HFD3_k127_5557005_5 Oxidoreductase - - - 0.00000000000000000000000003094 109.0
HFD3_k127_5559472_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1456.0
HFD3_k127_5559472_1 Protein of unknown function (DUF3347) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004748 440.0
HFD3_k127_5559472_2 Outer membrane efflux protein K15725 - - 0.00000000000008147 82.0
HFD3_k127_5567943_0 Planctomycete cytochrome C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005218 502.0
HFD3_k127_5567943_1 Protein of unknown function (DUF1501) - - - 0.0000000000000000009543 91.0
HFD3_k127_5568294_0 CotH kinase protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009356 576.0
HFD3_k127_5582661_0 and related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 552.0
HFD3_k127_5582661_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 496.0
HFD3_k127_5582661_2 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K04496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003971 420.0
HFD3_k127_5582661_3 Bacterial Ig-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 396.0
HFD3_k127_5582661_4 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 370.0
HFD3_k127_5582661_5 Putative neutral zinc metallopeptidase K06973 - - 0.000000000000000000000000000000000000000000000000000000005204 208.0
HFD3_k127_5582661_6 pyrroloquinoline quinone binding - - - 0.0000000000000000000000000000000001734 151.0
HFD3_k127_5582661_7 unsaturated chondroitin disaccharide hydrolase activity - - - 0.000004127 48.0
HFD3_k127_5595656_0 COG2804 Type II secretory pathway ATPase PulE Tfp pilus assembly pathway ATPase PilB K02454,K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 584.0
HFD3_k127_5595656_1 PFAM Copper type II ascorbate-dependent monooxygenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 460.0
HFD3_k127_5595656_2 Type 4 fimbrial assembly protein pilC K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 321.0
HFD3_k127_5595656_3 Concanavalin A-like lectin/glucanases superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000002407 240.0
HFD3_k127_5595656_4 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000000000000000000000000000000004258 241.0
HFD3_k127_5595656_5 Type II secretion system (T2SS), protein K - - - 0.000000000000000000000000000000000000000000000004572 191.0
HFD3_k127_5595656_6 peroxiredoxin activity - - - 0.000000000000000000000000000000000000000006365 167.0
HFD3_k127_5595656_7 general secretion pathway protein K02456 - - 0.00000000000000000003806 100.0
HFD3_k127_5595656_8 Type IV pilus assembly protein PilM K02662 - - 0.000002384 60.0
HFD3_k127_5595656_9 General secretion pathway protein - - - 0.00001278 56.0
HFD3_k127_5600759_0 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005049 469.0
HFD3_k127_5600759_1 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006426 280.0
HFD3_k127_5600759_2 radical SAM domain protein K13601,K13602 - 2.1.1.331,2.1.1.332 0.0000000000000000000000000000000000000000000000000002497 186.0
HFD3_k127_5600759_3 - - - - 0.000000000000000000000000000001627 124.0
HFD3_k127_5606113_0 COG3119 Arylsulfatase A and related enzymes - - - 9.951e-198 660.0
HFD3_k127_5606113_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 490.0
HFD3_k127_5606113_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000001101 213.0
HFD3_k127_5625085_0 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008501 422.0
HFD3_k127_5625085_1 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001734 302.0
HFD3_k127_5625085_2 Dihydro-orotase-like K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000005285 175.0
HFD3_k127_5625954_0 Methyltransferase type 11 K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004539 309.0
HFD3_k127_5625954_1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000119 273.0
HFD3_k127_5625954_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000001009 157.0
HFD3_k127_5625954_3 membrane - - - 0.00000000000000000000000000000001023 139.0
HFD3_k127_5625954_4 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03767 - 5.2.1.8 0.0000000000000000000000000000103 138.0
HFD3_k127_5626398_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008095 617.0
HFD3_k127_5626398_1 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 576.0
HFD3_k127_5626398_2 Polynucleotide adenylyltransferase K00974 - 2.7.7.72 0.00000348 53.0
HFD3_k127_5646328_0 general secretion pathway protein D K02453 - - 0.000000000000000000000000002236 130.0
HFD3_k127_5646328_1 Type II secretion system (T2SS), protein K - - - 0.00001764 55.0
HFD3_k127_5652887_0 CotH kinase protein - - - 8.8e-207 684.0
HFD3_k127_5661921_0 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003784 277.0
HFD3_k127_5661921_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000004956 222.0
HFD3_k127_5661921_2 Protein of unknown function (DUF3570) - - - 0.0000000000000000000000000000000000000000000000000000000000102 226.0
HFD3_k127_5661921_3 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000007036 157.0
HFD3_k127_5661921_4 Thioredoxin-like - - - 0.0000000000000000000000000005109 121.0
HFD3_k127_5661921_5 Domain of unknown function (DUF4266) - - - 0.000000000000003267 84.0
HFD3_k127_5661921_6 Regulator of chromosome condensation (RCC1) repeat - - - 0.00000009163 64.0
HFD3_k127_5679674_0 Similarity to COG0471 Di- and tricarboxylate transporters(Evalue K14445 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003857 500.0
HFD3_k127_5679674_1 and related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004077 464.0
HFD3_k127_5679674_11 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K01760 - 4.4.1.8 0.000003473 57.0
HFD3_k127_5679674_2 Right handed beta helix region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 430.0
HFD3_k127_5679674_3 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 419.0
HFD3_k127_5679674_4 beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 391.0
HFD3_k127_5679674_5 beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000427 377.0
HFD3_k127_5679674_6 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003288 357.0
HFD3_k127_5679674_7 2-keto-4-pentenoate hydratase - - - 0.0000000000000000000000000000000000000000000000000000002545 205.0
HFD3_k127_5679674_8 Sigma-70, region 4 K03088 - - 0.0000000000000004544 86.0
HFD3_k127_5679674_9 Protein of unknown function (DUF1573) - - - 0.000000004083 68.0
HFD3_k127_5687409_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 328.0
HFD3_k127_5687409_1 cheY-homologous receiver domain - - - 0.000000000000001003 80.0
HFD3_k127_5690318_0 ASPIC UnbV domain protein - - - 1.698e-293 944.0
HFD3_k127_5690318_1 ASPIC UnbV domain protein - - - 1.241e-286 929.0
HFD3_k127_5690318_2 PFAM Uncharacterised BCR, COG1649 - - - 0.00000000000000000000006836 109.0
HFD3_k127_5712908_0 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006114 363.0
HFD3_k127_5712908_1 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 347.0
HFD3_k127_5712908_2 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.0000000000000000000000000000000000000000000003247 175.0
HFD3_k127_5721135_0 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 488.0
HFD3_k127_5721135_2 FR47-like protein K03823 - 2.3.1.183 0.000000000000273 70.0
HFD3_k127_5731364_0 Peptidase MA superfamily - - - 2.187e-244 783.0
HFD3_k127_5731364_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 1.382e-225 706.0
HFD3_k127_5731364_10 LysE type translocator - - - 0.0000000000000000000000000005595 123.0
HFD3_k127_5731364_12 Glucose / Sorbosone dehydrogenase K00428,K01083,K01728 - 1.11.1.5,3.1.3.8,4.2.2.2 0.00000000373 68.0
HFD3_k127_5731364_2 peptidyl-tyrosine sulfation - - - 1.547e-203 674.0
HFD3_k127_5731364_3 PFAM ATPase associated with various cellular activities AAA_3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000979 486.0
HFD3_k127_5731364_4 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 409.0
HFD3_k127_5731364_5 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 357.0
HFD3_k127_5731364_6 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 344.0
HFD3_k127_5731364_7 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000001424 254.0
HFD3_k127_5731364_8 TIGRFAM riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000001634 203.0
HFD3_k127_5731364_9 Transcriptional regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000009467 205.0
HFD3_k127_5739034_0 Binding-protein-dependent transport system inner membrane component K02037,K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005396 607.0
HFD3_k127_5739034_1 phosphate transport system permease protein K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008524 582.0
HFD3_k127_5739034_2 COG0226 ABC-type phosphate transport system periplasmic K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 398.0
HFD3_k127_5739034_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000675 373.0
HFD3_k127_5739034_4 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005232 273.0
HFD3_k127_5739034_5 Protein of unknown function (DUF2959) - - - 0.000000000000000000000000000000000000000000000000000000000001684 218.0
HFD3_k127_5739034_6 - - - - 0.0000000000000000000000000000003959 129.0
HFD3_k127_5739034_7 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000004594 125.0
HFD3_k127_5739034_8 Putative porin - - - 0.0000000000000001654 93.0
HFD3_k127_5768938_0 nitrite sulfite reductase hemoprotein beta-component ferrodoxin domain protein K00366 - 1.7.7.1 6.364e-210 675.0
HFD3_k127_5768938_1 Oxidoreductase NAD-binding domain K00380 - 1.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 606.0
HFD3_k127_5768938_2 O-Antigen ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 424.0
HFD3_k127_5768938_3 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 307.0
HFD3_k127_5768938_4 Endonuclease I - - - 0.000003205 51.0
HFD3_k127_5775801_0 Protein of unknown function (DUF1549) - - - 1.158e-301 956.0
HFD3_k127_5775801_1 Concanavalin A-like lectin/glucanases superfamily - - - 2.224e-239 780.0
HFD3_k127_5775801_10 EamA-like transporter family - - - 0.00000000000001234 83.0
HFD3_k127_5775801_11 VTC domain - - - 0.0000006562 60.0
HFD3_k127_5775801_2 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 596.0
HFD3_k127_5775801_3 Belongs to the hyi family K01816 - 5.3.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 326.0
HFD3_k127_5775801_4 TIGRFAM hopanoid biosynthesis associated protein HpnK - - - 0.000000000000000000000000000000000000000000000000000000005133 215.0
HFD3_k127_5775801_5 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.000000000000000000000000000000000009091 143.0
HFD3_k127_5775801_6 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000005793 117.0
HFD3_k127_5775801_7 Glycosyltransferase Family 4 K02844 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008194,GO:0008610,GO:0008653,GO:0008919,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046401,GO:0046527,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.0000000000000001971 88.0
HFD3_k127_5775801_8 Phosphorylase superfamily K01243 - 3.2.2.9 0.0000000000000002405 88.0
HFD3_k127_5775801_9 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.00000000000000415 76.0
HFD3_k127_5787865_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006619 573.0
HFD3_k127_5787865_1 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 334.0
HFD3_k127_5787865_2 Nucleotidyl transferase of unknown function (DUF2204) - - - 0.00000000000000000000003734 105.0
HFD3_k127_5823887_0 - - - - 1.334e-262 830.0
HFD3_k127_5823887_1 PFAM VWA domain containing CoxE-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 579.0
HFD3_k127_5823887_2 associated with various cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 309.0
HFD3_k127_5823887_3 cellulose binding - - - 0.000000000000000000000000000000000000000133 168.0
HFD3_k127_5823887_4 - - - - 0.0000000000000000000000000000000000009464 147.0
HFD3_k127_5823887_5 - - - - 0.000000000000000000000000002424 130.0
HFD3_k127_5826604_0 anaphase-promoting complex binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 400.0
HFD3_k127_5826604_1 Protein of unknown function (DUF3500) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009592 358.0
HFD3_k127_5826604_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000394 234.0
HFD3_k127_5826604_3 Wd-40 repeat - - - 0.000000000000000000000000000000000002323 157.0
HFD3_k127_5846299_0 Cysteine-rich domain K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006001 520.0
HFD3_k127_5846299_1 type II secretion K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005171 411.0
HFD3_k127_5846299_2 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009814 290.0
HFD3_k127_5863559_0 Protein of unknown function (DUF1501) - - - 5.257e-207 653.0
HFD3_k127_5863559_1 Planctomycete cytochrome C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 591.0
HFD3_k127_5875597_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.071e-252 805.0
HFD3_k127_5875597_1 NYN domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003547 408.0
HFD3_k127_5875597_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000002656 58.0
HFD3_k127_5875597_3 Caspase domain K07369 GO:0001650,GO:0001775,GO:0001817,GO:0001819,GO:0001923,GO:0001932,GO:0001934,GO:0002020,GO:0002218,GO:0002220,GO:0002223,GO:0002237,GO:0002253,GO:0002335,GO:0002376,GO:0002429,GO:0002520,GO:0002521,GO:0002682,GO:0002684,GO:0002694,GO:0002696,GO:0002697,GO:0002699,GO:0002700,GO:0002702,GO:0002703,GO:0002705,GO:0002706,GO:0002708,GO:0002709,GO:0002711,GO:0002718,GO:0002720,GO:0002724,GO:0002726,GO:0002757,GO:0002758,GO:0002764,GO:0002768,GO:0002819,GO:0002821,GO:0002822,GO:0002824,GO:0003674,GO:0003824,GO:0004175,GO:0004197,GO:0004842,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0005829,GO:0006355,GO:0006464,GO:0006508,GO:0006807,GO:0006810,GO:0006913,GO:0006950,GO:0006952,GO:0006955,GO:0007154,GO:0007165,GO:0007166,GO:0007250,GO:0007275,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0008283,GO:0009605,GO:0009607,GO:0009617,GO:0009620,GO:0009889,GO:0009893,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0010562,GO:0010604,GO:0010646,GO:0010647,GO:0010941,GO:0016043,GO:0016567,GO:0016740,GO:0016787,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0019787,GO:0019899,GO:0022407,GO:0022409,GO:0022607,GO:0023051,GO:0023052,GO:0023056,GO:0030097,GO:0030098,GO:0030154,GO:0030155,GO:0030183,GO:0031323,GO:0031325,GO:0031326,GO:0031347,GO:0031349,GO:0031396,GO:0031398,GO:0031399,GO:0031401,GO:0031974,GO:0031981,GO:0032147,GO:0032268,GO:0032270,GO:0032446,GO:0032449,GO:0032501,GO:0032502,GO:0032663,GO:0032743,GO:0032943,GO:0032991,GO:0033674,GO:0035556,GO:0036211,GO:0038061,GO:0038093,GO:0038095,GO:0042098,GO:0042110,GO:0042113,GO:0042221,GO:0042325,GO:0042327,GO:0042802,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043085,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043370,GO:0043372,GO:0043412,GO:0043549,GO:0043621,GO:0043933,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044452,GO:0044464,GO:0045087,GO:0045088,GO:0045089,GO:0045321,GO:0045580,GO:0045582,GO:0045595,GO:0045597,GO:0045619,GO:0045621,GO:0045622,GO:0045624,GO:0045785,GO:0045859,GO:0045860,GO:0045937,GO:0046634,GO:0046635,GO:0046637,GO:0046638,GO:0046649,GO:0046651,GO:0046907,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048583,GO:0048584,GO:0048731,GO:0048856,GO:0048869,GO:0050776,GO:0050778,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050851,GO:0050852,GO:0050854,GO:0050856,GO:0050863,GO:0050865,GO:0050867,GO:0050870,GO:0050896,GO:0051090,GO:0051091,GO:0051092,GO:0051094,GO:0051168,GO:0051169,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051249,GO:0051251,GO:0051252,GO:0051259,GO:0051338,GO:0051347,GO:0051641,GO:0051649,GO:0051704,GO:0051707,GO:0051716,GO:0060255,GO:0060548,GO:0065003,GO:0065007,GO:0065009,GO:0070011,GO:0070013,GO:0070647,GO:0070661,GO:0071704,GO:0071840,GO:0080090,GO:0080134,GO:0140096,GO:1901222,GO:1901224,GO:1901564,GO:1902105,GO:1902107,GO:1902531,GO:1902533,GO:1903037,GO:1903039,GO:1903320,GO:1903322,GO:1903506,GO:1903706,GO:1903708,GO:2000026,GO:2000112,GO:2000316,GO:2000318,GO:2000319,GO:2000321,GO:2000514,GO:2000516,GO:2001141 - 0.00008475 53.0
HFD3_k127_5902650_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002083 316.0
HFD3_k127_5902650_1 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 0.000000000000000000000000000000000000000000000000000000000000203 221.0
HFD3_k127_5902650_2 Type II secretion system (T2SS), protein F K12278 - - 0.00000000007701 74.0
HFD3_k127_5902650_3 COG1459 Type II secretory pathway, component PulF K02455 GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776 - 0.00001359 57.0
HFD3_k127_5902672_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 431.0
HFD3_k127_5902672_1 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009062 373.0
HFD3_k127_5902672_2 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000005572 141.0
HFD3_k127_5902672_3 Spore coat protein CotH K01216,K07004 - 3.2.1.73 0.0000000000000000000006143 108.0
HFD3_k127_5902672_4 calcium ion binding K08670 - 3.4.21.109 0.000003167 59.0
HFD3_k127_5910419_0 FtsK/SpoIIIE family - - - 0.0 1229.0
HFD3_k127_5910419_1 CotH kinase protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000495 534.0
HFD3_k127_5910419_10 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000002466 104.0
HFD3_k127_5910419_11 Domain of unknown function (DUF3368) K07066 - - 0.00000000000000000000001046 106.0
HFD3_k127_5910419_12 - - - - 0.00000000000000000000002281 110.0
HFD3_k127_5910419_13 Spore coat protein CotH K01216,K07004 - 3.2.1.73 0.00000000000003486 86.0
HFD3_k127_5910419_14 Required for transformation and DNA binding K02245,K02456 GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944 - 0.0000000005936 68.0
HFD3_k127_5910419_15 Protein of unknown function (DUF1559) - - - 0.00000002359 65.0
HFD3_k127_5910419_2 Putative Na+/H+ antiporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 466.0
HFD3_k127_5910419_3 COG5337 Spore coat assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 379.0
HFD3_k127_5910419_4 CotH kinase protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000412 252.0
HFD3_k127_5910419_5 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000000000005595 244.0
HFD3_k127_5910419_6 - - - - 0.00000000000000000000000000000000000000009208 157.0
HFD3_k127_5910419_7 - - - - 0.0000000000000000000000000000000005654 150.0
HFD3_k127_5910419_8 Proteins of 100 residues with WXG - - - 0.000000000000000000000000000000004434 131.0
HFD3_k127_595945_0 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 593.0
HFD3_k127_595945_1 Mur ligase family, catalytic domain K02558 - 6.3.2.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006471 511.0
HFD3_k127_595945_10 PFAM Immunoglobulin I-set domain - - - 0.00000001801 70.0
HFD3_k127_595945_2 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000001268 243.0
HFD3_k127_595945_3 TIGRFAM conserved repeat domain - - - 0.00000000000000000000000000000000000000000000000000247 213.0
HFD3_k127_595945_4 antibiotic catabolic process K01406,K02414,K07004,K13277,K21449 - 3.4.24.40 0.0000000000000000000000000000000000000000004069 185.0
HFD3_k127_595945_5 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000567 131.0
HFD3_k127_595945_6 Domain of unknown function (DUF4842) - - - 0.000000000000000000000000008353 131.0
HFD3_k127_595945_7 S-layer homology domain - - - 0.00000000000001162 91.0
HFD3_k127_595945_8 Dystroglycan-type cadherin-like domains. - - - 0.00000000000001162 91.0
HFD3_k127_595945_9 Major facilitator Superfamily K01256,K16210 - 3.4.11.2 0.00000000004324 75.0
HFD3_k127_5989776_0 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000812 253.0
HFD3_k127_5989776_1 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000008086 146.0
HFD3_k127_5989776_2 In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold. K05785 GO:0001000,GO:0001073,GO:0001121,GO:0001124,GO:0003674,GO:0003676,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006355,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008494,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031554,GO:0031564,GO:0032268,GO:0032270,GO:0032774,GO:0034248,GO:0034250,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045182,GO:0045727,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090079,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.000000000002001 74.0
HFD3_k127_5989848_0 CotH kinase protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 428.0
HFD3_k127_6003111_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.0 1030.0
HFD3_k127_6003111_1 TIGRFAM RNA polymerase sigma-54 factor, RpoN K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 523.0
HFD3_k127_6003111_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001031 257.0
HFD3_k127_6003111_3 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000852 256.0
HFD3_k127_6003111_5 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000929 94.0
HFD3_k127_6004667_0 CotH kinase protein - - - 0.0 1078.0
HFD3_k127_6004667_1 Immunoglobulin I-set domain protein - - - 0.00000000000000000001332 110.0
HFD3_k127_6004667_2 Pectate lyase K01732,K20276 - 4.2.2.10 0.000000000000083 87.0
HFD3_k127_6021494_0 DNA methylase K00590 - 2.1.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 492.0
HFD3_k127_6021494_1 Nucleoside diphosphate kinase K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005683 489.0
HFD3_k127_6021494_2 with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine K01658,K01664 - 2.6.1.85,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 284.0
HFD3_k127_6021494_3 A G-specific adenine glycosylase K03574,K03575 - 3.6.1.55 0.000000000000000000000000000003544 123.0
HFD3_k127_6021494_4 - - - - 0.000000002245 66.0
HFD3_k127_6029963_0 PFAM sigma-54 factor interaction domain-containing protein K02481,K07714,K10943 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 397.0
HFD3_k127_6029963_1 Aminotransferase class-III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007404 364.0
HFD3_k127_6029963_2 TIGRFAM autotransporter-associated beta strand repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000001105 247.0
HFD3_k127_6029963_3 NUDIX hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000001739 217.0
HFD3_k127_6029963_4 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000006314 217.0
HFD3_k127_6029963_5 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000000000000000000000000000000000000423 183.0
HFD3_k127_6029963_6 PFAM ATP-binding region, ATPase domain protein K02482 - 2.7.13.3 0.00000000000000000000000000001044 135.0
HFD3_k127_6029963_7 Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000563 112.0
HFD3_k127_6038530_0 Zinc metalloprotease (Elastase) K20274 - - 3.937e-223 739.0
HFD3_k127_6038530_1 cellulase activity - - - 0.0000001255 66.0
HFD3_k127_6046808_0 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 401.0
HFD3_k127_6046808_1 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000006801 191.0
HFD3_k127_6046808_2 Histidine kinase-like ATPase domain - - - 0.0000000000000000000000000001858 123.0
HFD3_k127_6046808_3 domain, Protein - - - 0.0000000000007505 80.0
HFD3_k127_6046808_4 STAS domain - - - 0.0000004912 59.0
HFD3_k127_6046808_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000008774 49.0
HFD3_k127_6050434_0 Autotransporter beta-domain - - - 0.0000000000000000000000000000000000000000007529 182.0
HFD3_k127_6050434_1 Protein kinase domain - - - 0.00000000444 67.0
HFD3_k127_6083805_0 SRP54-type protein, GTPase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007229 419.0
HFD3_k127_6083805_1 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004574 293.0
HFD3_k127_6083805_2 Alcohol dehydrogenase GroES-like domain K00060 - 1.1.1.103 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001833 267.0
HFD3_k127_6083805_3 Chlorite dismutase - - - 0.000000000000000000000000000000000000000000000000000000000000001555 228.0
HFD3_k127_6083805_4 Glycine cleavage H-protein - - - 0.000000000000000000000000000000000000000000000000001461 191.0
HFD3_k127_6083805_5 acid phosphatase activity - - - 0.000000000000000000000000000000000000001876 162.0
HFD3_k127_6083805_6 Tetratricopeptide repeat - - - 0.0000000000000003473 89.0
HFD3_k127_6120500_0 Sucrose-6F-phosphate phosphohydrolase K13086 - 3.1.3.79 1.371e-306 955.0
HFD3_k127_6120500_1 Glycosyl transferases group 1 K13058 - 2.4.1.246 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006074 557.0
HFD3_k127_6120500_2 Chromate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006076 486.0
HFD3_k127_6120500_3 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000000000000000000000000000000003073 184.0
HFD3_k127_6120500_4 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000000000000000000000000006603 143.0
HFD3_k127_6130333_0 glycosyl transferase - - - 0.000000000000000000000000000000000000000000007735 176.0
HFD3_k127_6130333_1 Protein of unknown function (DUF1559) - - - 0.0000000000000000008504 98.0
HFD3_k127_6191506_0 ASPIC UnbV domain protein - - - 8.273e-282 909.0
HFD3_k127_6191506_1 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 550.0
HFD3_k127_6191506_10 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00001491 56.0
HFD3_k127_6191506_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000042 452.0
HFD3_k127_6191506_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 426.0
HFD3_k127_6191506_4 Xylose isomerase-like TIM barrel K03335 - 4.2.1.44 0.0000000000000000000000000000000000000000003488 170.0
HFD3_k127_6191506_5 FabA-like domain - - - 0.0000000000000000000000000000000000000000005182 175.0
HFD3_k127_6191506_6 Outer membrane lipoprotein carrier protein LolA - - - 0.000000000000000000000000000006365 136.0
HFD3_k127_6191506_7 Bacterial lipid A biosynthesis acyltransferase - - - 0.00000000000000000004923 103.0
HFD3_k127_6191506_8 Phospholipid N-methyltransferase - - - 0.0000000000009604 77.0
HFD3_k127_6191506_9 Forkhead associated domain - - - 0.0000000001541 74.0
HFD3_k127_6198342_0 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0000000000000000000000000000000000000000000000000000002932 218.0
HFD3_k127_6198342_1 Belongs to the peptidase S8 family - - - 0.0000000000000002907 93.0
HFD3_k127_6234570_0 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007049 524.0
HFD3_k127_6234570_1 Xylose isomerase domain protein TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005992 460.0
HFD3_k127_6234570_2 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 391.0
HFD3_k127_6234570_3 UbiA prenyltransferase family - - - 0.0000000000000000000000000000000000000000000189 172.0
HFD3_k127_6254360_0 AAA domain K07028 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 353.0
HFD3_k127_6254360_1 Zinc transporter K07238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 347.0
HFD3_k127_6254360_2 PFAM helix-turn-helix- domain containing protein AraC type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004818 328.0
HFD3_k127_6254360_3 - - - - 0.00000000000000000000000000000000000000000006258 167.0
HFD3_k127_6254360_4 Belongs to the glycosyl hydrolase 13 family - - - 0.00000000000000002402 90.0
HFD3_k127_6261164_0 elongation factor Tu domain 2 protein K06207 - - 3.247e-258 812.0
HFD3_k127_6261164_1 C-terminal domain of CHU protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004732 408.0
HFD3_k127_6261164_2 PFAM coagulation factor 5 8 type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 337.0
HFD3_k127_6261164_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000003924 259.0
HFD3_k127_6261322_0 Prokaryotic homologs of the JAB domain - - - 0.00000007842 62.0
HFD3_k127_6261322_1 ATPase family associated with various cellular activities (AAA) K14575 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022613,GO:0030554,GO:0030684,GO:0030687,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042221,GO:0042254,GO:0042273,GO:0042493,GO:0043167,GO:0043168,GO:0044085,GO:0044464,GO:0050896,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904 - 0.00000008303 65.0
HFD3_k127_6261322_2 PFAM UBA THIF-type NAD FAD binding protein - - - 0.00004114 55.0
HFD3_k127_6272434_0 PFAM NADH Ubiquinone plastoquinone (complex I) K12137 - - 9.27e-288 904.0
HFD3_k127_6272434_1 PFAM NADH Ubiquinone plastoquinone (complex I) K12137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008698 558.0
HFD3_k127_6272434_2 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004299 304.0
HFD3_k127_6272434_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000009673 182.0
HFD3_k127_6272434_4 phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 - - - 0.0000000006636 68.0
HFD3_k127_6272434_5 - K13582,K13924,K15580 - 2.1.1.80,3.1.1.61 0.00001318 55.0
HFD3_k127_6273758_0 COG3209 Rhs family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 372.0
HFD3_k127_6273758_1 esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002469 276.0
HFD3_k127_6273758_2 Lamin Tail Domain K07004 - - 0.000000000000000000000000000000000000000000001997 192.0
HFD3_k127_6273758_3 amine dehydrogenase activity - GO:0005575,GO:0005576 - 0.0000000000000000000000000000000000000001539 176.0
HFD3_k127_6273758_4 Fibronectin type III domain protein - - - 0.0000000000001722 87.0
HFD3_k127_6273758_5 PFAM TadE family protein K12287 - - 0.000000000008014 81.0
HFD3_k127_6273758_6 Beta-1,3-glucanase - - - 0.0000000002834 76.0
HFD3_k127_6287214_0 Two component, sigma54 specific, transcriptional regulator, Fis family K11384 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 525.0
HFD3_k127_6287214_1 HAMP domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000626 465.0
HFD3_k127_6297466_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18299,K18902 - - 0.0 1477.0
HFD3_k127_6297466_1 Dihydrodipicolinate synthetase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 455.0
HFD3_k127_6297466_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K18901 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 396.0
HFD3_k127_6297466_3 Formyl transferase K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000001503 218.0
HFD3_k127_6297466_4 Bacterial transcriptional repressor C-terminal - - - 0.0000000000000000000000000000000000000000000000000000003294 201.0
HFD3_k127_6297466_5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000000000000000000000000000006907 135.0
HFD3_k127_6299302_0 ATPase activity K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 362.0
HFD3_k127_6299302_1 Heavy metal translocating P-type atpase K01534,K17686 - 3.6.3.3,3.6.3.5,3.6.3.54 0.00000000000000000000000000000000000000000000000005526 184.0
HFD3_k127_6299302_2 peptidoglycan binding K03642 - - 0.000000000000000000000000000000000000001436 166.0
HFD3_k127_6299302_3 NUDIX domain - - - 0.00000000001734 65.0
HFD3_k127_6304838_0 Belongs to the glycosyl hydrolase 43 family K22350 - 1.16.3.3 3.045e-219 740.0
HFD3_k127_6304838_1 PFAM RNP-1 like RNA-binding protein - - - 0.000000000000000000000000000000000406 134.0
HFD3_k127_6304838_2 Dihydrodipicolinate synthetase family K01639 - 4.1.3.3 0.0000000000000000000000000009522 114.0
HFD3_k127_6304838_3 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000003401 131.0
HFD3_k127_6309566_0 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 559.0
HFD3_k127_6309566_1 - - - - 0.0005261 46.0
HFD3_k127_631191_0 membrane protein involved in D-alanine export - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007466 411.0
HFD3_k127_631191_1 Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009012 326.0
HFD3_k127_631191_2 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000001666 272.0
HFD3_k127_631191_3 Endonuclease Exonuclease phosphatase - - - 0.000000000000000000000000000000000000754 156.0
HFD3_k127_631191_4 Required for transformation and DNA binding K02245,K02456 GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000009479 77.0
HFD3_k127_6315414_0 transferase activity, transferring acyl groups K14658,K17840,K18815 - 2.3.1.59,2.3.1.82 6.711e-201 658.0
HFD3_k127_6315414_1 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000004085 238.0
HFD3_k127_6332011_0 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000007388 243.0
HFD3_k127_6332011_1 Trypsin-like peptidase domain - - - 0.00002281 51.0
HFD3_k127_6332011_2 Trypsin-like peptidase domain - - - 0.00008419 48.0
HFD3_k127_6332934_0 Cytochrome c554 and c-prime - - - 0.0 1079.0
HFD3_k127_6332934_1 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 610.0
HFD3_k127_6332934_2 PFAM Haemolysin-type calcium-binding repeat - - - 0.0000000000000000000000000000000000000001301 175.0
HFD3_k127_6332934_3 Transcription factor zinc-finger - - - 0.00000000000000000000000000000000000001768 148.0
HFD3_k127_6332934_4 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000002992 164.0
HFD3_k127_6332934_5 Multi-sensor signal transduction multi-kinase - - - 0.00000000000000008778 90.0
HFD3_k127_6332934_6 domain protein - - - 0.000000000601 74.0
HFD3_k127_6332934_7 general secretion pathway protein K02456 - - 0.00009372 53.0
HFD3_k127_6333204_0 alpha beta - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002819 464.0
HFD3_k127_6333204_1 acid phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000002877 235.0
HFD3_k127_6342612_0 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000003829 269.0
HFD3_k127_6342612_1 DisA bacterial checkpoint controller nucleotide-binding - - - 0.000000000000000000000000000000000000000000000000000004364 201.0
HFD3_k127_6342612_2 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K05827,K05844 - 6.3.2.43 0.000000000000000000000000000000000000001126 155.0
HFD3_k127_6342612_3 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000414 64.0
HFD3_k127_6359162_0 peptidase S9A, prolyl oligopeptidase domain protein beta-propeller K01354 - 3.4.21.83 1.187e-310 1001.0
HFD3_k127_6359162_1 Tannase and feruloyl esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005105 479.0
HFD3_k127_6359162_2 - - - - 0.0000000000000000000000000000000000000000001498 161.0
HFD3_k127_6359162_3 YCII-related domain - - - 0.0000000000000000000000000000000000000003229 153.0
HFD3_k127_6359162_4 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.0000000000000000000000000000000000000006624 152.0
HFD3_k127_6359162_5 Domain of unknown function (DUF4287) - - - 0.0000000000000000000000000000000003012 132.0
HFD3_k127_6359162_6 Endonuclease Exonuclease Phosphatase - - - 0.0000000000000000000000000006029 115.0
HFD3_k127_6359162_7 - - GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007 - 0.00000000000003743 79.0
HFD3_k127_637749_0 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 524.0
HFD3_k127_637749_1 dUTPase - - - 0.00000000000000000000000000000000000000000000000000000001099 200.0
HFD3_k127_637749_2 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000003463 203.0
HFD3_k127_637749_3 MotA/TolQ/ExbB proton channel family K03561 - - 0.00000000000000000000000000000000000000000000001361 179.0
HFD3_k127_637749_4 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.0000000003595 63.0
HFD3_k127_637749_5 biopolymer transport protein K03559 - - 0.000000143 62.0
HFD3_k127_6382691_0 Planctomycete cytochrome C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 416.0
HFD3_k127_6382691_1 Sigma-70 region 3 K02405 - - 0.0000000000000000000000000000000000000000000000000000000321 212.0
HFD3_k127_6382691_2 - - - - 0.00000000000000001873 95.0
HFD3_k127_6387344_0 Cytochrome c - - - 1.559e-241 760.0
HFD3_k127_6387344_1 Protein of unknown function (DUF455) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005429 430.0
HFD3_k127_6387344_2 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 390.0
HFD3_k127_6389994_0 Spore coat protein CotH K01216,K07004 - 3.2.1.73 0.0000000000000000000000000000000000000000000000000000003534 222.0
HFD3_k127_6389994_1 Lactonase, 7-bladed beta-propeller - - - 0.000000000000000000000000000000000000000007722 178.0
HFD3_k127_6389994_2 alkaline phosphatase - - - 0.000000006052 70.0
HFD3_k127_6430949_0 Trehalose utilisation - - - 2.666e-300 962.0
HFD3_k127_6430949_1 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 365.0
HFD3_k127_6430949_2 Control of competence regulator ComK, YlbF/YmcA - - - 0.00000000000000000000000001983 113.0
HFD3_k127_6449325_0 Spore coat protein CotH K01216,K07004 - 3.2.1.73 0.0000000000000000000000000000000000000000000000000000000000000000001391 264.0
HFD3_k127_6449325_1 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000009099 156.0
HFD3_k127_6449325_2 CotH kinase protein - - - 0.000000000000000000000000000004168 141.0
HFD3_k127_6449325_3 Subtilase family - - - 0.00000139 63.0
HFD3_k127_646227_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 583.0
HFD3_k127_646227_1 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005833 302.0
HFD3_k127_6479405_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.0 1066.0
HFD3_k127_6479405_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 8.725e-200 627.0
HFD3_k127_6479405_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.0000000000000000000000000000000000000000000000000000001318 198.0
HFD3_k127_6480891_0 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 376.0
HFD3_k127_6480891_1 Beta-Casp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 368.0
HFD3_k127_6480891_2 Protein of unknown function DUF111 K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 353.0
HFD3_k127_6480891_3 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005298 273.0
HFD3_k127_6480891_4 Ferredoxin K02230 - 6.6.1.2 0.0000000000000000000000000000000000000001015 155.0
HFD3_k127_6480891_5 tetraacyldisaccharide 4'-kinase activity K09791 - - 0.00000000000000000000008322 99.0
HFD3_k127_6480891_6 - - - - 0.0000000000000000001704 95.0
HFD3_k127_6480891_7 Protein of unknown function (DUF1232) - - - 0.000000001677 64.0
HFD3_k127_6481169_0 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000004635 235.0
HFD3_k127_6481169_1 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000001318 180.0
HFD3_k127_6481169_2 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000004331 112.0
HFD3_k127_6495207_0 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase K00322 - 1.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 484.0
HFD3_k127_6495207_1 TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 416.0
HFD3_k127_6495207_2 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003996 424.0
HFD3_k127_6495207_3 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 409.0
HFD3_k127_6495207_4 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 396.0
HFD3_k127_6495207_5 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 388.0
HFD3_k127_6495207_6 Belongs to the TrpC family K01609,K13498 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48,5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000007854 262.0
HFD3_k127_6495207_7 - - - - 0.00000004626 58.0
HFD3_k127_6501096_0 CBS domain-containing protein K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 349.0
HFD3_k127_6501096_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001357 262.0
HFD3_k127_6501096_2 CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000727 192.0
HFD3_k127_6501096_3 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000004189 134.0
HFD3_k127_6501096_4 Mg2 and Co2 transporter CorB - - - 0.0000000000000000000000000005193 128.0
HFD3_k127_6508607_0 Phosphate acyltransferases K05939 - 2.3.1.40,6.2.1.20 4.121e-285 894.0
HFD3_k127_6508607_1 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001787 261.0
HFD3_k127_6508607_2 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000381 76.0
HFD3_k127_6508607_3 Belongs to the UPF0235 family K09131 - - 0.0000000000001192 79.0
HFD3_k127_6511290_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1173.0
HFD3_k127_6511290_1 aspartyl asparaginyl beta-hydroxylase K12979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 392.0
HFD3_k127_6511290_2 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007918 279.0
HFD3_k127_6511290_3 Permease MlaE - - - 0.00000000000000000000000000000000000000000000000000000000000000000001226 242.0
HFD3_k127_6511290_4 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.0000000008704 70.0
HFD3_k127_6521543_0 type II secretion system protein E K02652 - - 2.463e-209 683.0
HFD3_k127_6521543_1 General secretory system II protein E domain protein K02454,K02652 - - 7.139e-205 652.0
HFD3_k127_6521543_2 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006312 450.0
HFD3_k127_6521543_3 type II secretion K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 466.0
HFD3_k127_6521543_4 alcohol dehydrogenase K00043 - 1.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006954 303.0
HFD3_k127_6522733_0 AcrB/AcrD/AcrF family - - - 0.0 1374.0
HFD3_k127_6522733_1 SMART Nucleotide binding protein, PINc K07175 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007541 467.0
HFD3_k127_6522733_2 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 304.0
HFD3_k127_6522733_3 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000002579 171.0
HFD3_k127_6522733_4 HlyD family secretion protein - - - 0.000000000000000000000000000000000000001084 155.0
HFD3_k127_6522733_5 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567,K10778 GO:0001130,GO:0003674,GO:0003700,GO:0003824,GO:0003908,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006355,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016740,GO:0016741,GO:0018125,GO:0018193,GO:0018198,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044728,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0046872,GO:0046914,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070988,GO:0071704,GO:0080090,GO:0080111,GO:0090304,GO:0140110,GO:1901360,GO:1901564,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 2.1.1.63 0.0000000000000000000008007 102.0
HFD3_k127_6522733_6 - - - - 0.0000006313 59.0
HFD3_k127_6543434_0 iron ion homeostasis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 638.0
HFD3_k127_6543434_1 domain protein K01637,K20276 - 4.1.3.1 0.000439 51.0
HFD3_k127_6543659_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002892 364.0
HFD3_k127_6543659_1 Di-glucose binding within endoplasmic reticulum - - - 0.000000000000000000000000000000000000000000000007699 199.0
HFD3_k127_6543659_2 Domain of Unknown Function (DUF1080) - - - 0.00000000005071 73.0
HFD3_k127_6543659_3 Spore coat protein CotH - - - 0.00000000009903 76.0
HFD3_k127_6587133_0 ABC transporter transmembrane region K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 456.0
HFD3_k127_6587133_1 SIS domain K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 295.0
HFD3_k127_6587133_2 GHMP kinase domain protein K07031 - 2.7.1.168 0.000000000000000000000000000000000000000000000003838 174.0
HFD3_k127_6587685_0 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000001086 192.0
HFD3_k127_6587685_1 Peptidase family S41 - - - 0.00000000000000005458 93.0
HFD3_k127_6591456_0 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 344.0
HFD3_k127_6591456_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000131 257.0
HFD3_k127_6591456_2 Putative ABC exporter - - - 0.000000000000000000003097 100.0
HFD3_k127_6591456_3 outer membrane autotransporter barrel domain protein - - - 0.000000000000000000007237 107.0
HFD3_k127_6627227_0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain - - - 7.814e-235 749.0
HFD3_k127_6627227_1 AMP-binding enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009444 604.0
HFD3_k127_6627227_2 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002865 549.0
HFD3_k127_6627227_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003907 419.0
HFD3_k127_6627227_4 Patatin-like phospholipase - - - 0.000000000000000000000000000000000000000000000000000000000006615 228.0
HFD3_k127_6627227_5 Domain of unknown function (DUF1802) - - - 0.000000000000000000000000000000004169 136.0
HFD3_k127_6627227_6 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03771 - 5.2.1.8 0.0000000000000000000000000000004058 137.0
HFD3_k127_6627227_7 Helix-turn-helix domain - - - 0.0000000006316 66.0
HFD3_k127_6668050_0 56kDa selenium binding protein (SBP56) K17285 - - 3.583e-209 659.0
HFD3_k127_6668050_1 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004316 438.0
HFD3_k127_6668050_2 Tetratricopeptide repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000001635 239.0
HFD3_k127_6668050_3 signal sequence binding K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000006177 237.0
HFD3_k127_6668050_4 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000000005517 201.0
HFD3_k127_6668050_5 Di-glucose binding within endoplasmic reticulum - - - 0.000000000000000000000000000000000000005443 169.0
HFD3_k127_6671849_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.0 1028.0
HFD3_k127_6671849_1 Tfp pilus assembly protein FimV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002927 296.0
HFD3_k127_668023_0 Aldehyde dehydrogenase family - - - 7.9e-248 773.0
HFD3_k127_668023_1 PQQ-like domain - - - 2.247e-218 687.0
HFD3_k127_668023_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 2.083e-208 651.0
HFD3_k127_668023_3 PFAM iron-containing alcohol dehydrogenase K00001 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003153 478.0
HFD3_k127_6683869_0 Domain of Unknown Function (DUF748) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005544 582.0
HFD3_k127_6683869_1 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000002153 81.0
HFD3_k127_6700400_0 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00381 - 1.8.1.2 1.27e-260 812.0
HFD3_k127_6700400_1 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955 - 2.7.1.25,2.7.7.4 2.883e-236 738.0
HFD3_k127_6700400_2 PFAM phosphoadenosine phosphosulfate reductase K00957 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009206 509.0
HFD3_k127_6700400_3 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003296 380.0
HFD3_k127_6700400_4 Catalyzes the synthesis of activated sulfate K00860,K00955 - 2.7.1.25,2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000005264 235.0
HFD3_k127_6700400_5 Predicted membrane protein (DUF2061) - - - 0.0000000000000000000002368 98.0
HFD3_k127_676085_0 Lipoprotein K04754 - - 0.0000000000000000000000000000001235 140.0
HFD3_k127_676085_1 cheY-homologous receiver domain - - - 0.000000000000004571 80.0
HFD3_k127_6768950_0 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K16363 - 3.5.1.108,4.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 471.0
HFD3_k127_6768950_1 CotH kinase protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007906 371.0
HFD3_k127_6768950_2 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 294.0
HFD3_k127_6768950_3 SMART Immunoglobulin C2 type - - - 0.000000000000000000001591 111.0
HFD3_k127_6768950_4 allophanate hydrolase subunit 1 - - - 0.00000000008252 67.0
HFD3_k127_6768950_5 CotH kinase protein - - - 0.000000651 63.0
HFD3_k127_6786_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005282 570.0
HFD3_k127_6786_1 Band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 386.0
HFD3_k127_6786_2 arylsulfatase activity - - - 0.00000000000000000000000000002439 135.0
HFD3_k127_6799215_0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 1.545e-205 651.0
HFD3_k127_6799215_1 POT family K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 544.0
HFD3_k127_680108_0 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 508.0
HFD3_k127_680108_1 COG1012 NAD-dependent aldehyde dehydrogenases K19588 - 1.2.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000001107 264.0
HFD3_k127_680108_2 pathogenesis K20276 - - 0.00000000000000000000000000003432 118.0
HFD3_k127_680108_3 Protein of unknown function (DUF3592) - - - 0.000003649 57.0
HFD3_k127_6806600_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 1.173e-210 665.0
HFD3_k127_6806600_1 radical SAM domain protein - - - 4.408e-207 656.0
HFD3_k127_6806600_2 PFAM Neutral alkaline nonlysosomal ceramidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006851 494.0
HFD3_k127_6806600_3 Proprotein convertase P-domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001495 289.0
HFD3_k127_6806600_4 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009459 244.0
HFD3_k127_6806600_5 PFAM ASPIC UnbV domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000003811 241.0
HFD3_k127_6806600_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000001343 183.0
HFD3_k127_6806600_7 Stress responsive A/B Barrel Domain - - - 0.0000000000000000000000000000000004921 136.0
HFD3_k127_6806600_8 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000001371 134.0
HFD3_k127_6806600_9 Uncharacterized protein conserved in bacteria (DUF2314) - - - 0.0000000000000000000001604 103.0
HFD3_k127_6812693_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 6.712e-246 772.0
HFD3_k127_6812693_1 IMP dehydrogenase GMP reductase K00088 - 1.1.1.205 1.179e-243 768.0
HFD3_k127_6812693_10 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000006654 228.0
HFD3_k127_6812693_11 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000003182 242.0
HFD3_k127_6812693_12 Flavoprotein K01598 - 4.1.1.36 0.000000000000000000000000000000000000000000000000000000000002429 216.0
HFD3_k127_6812693_13 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000000000002264 159.0
HFD3_k127_6812693_14 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000001287 98.0
HFD3_k127_6812693_15 KH domain K06960 - - 0.00000000000004984 74.0
HFD3_k127_6812693_16 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.0000000008438 61.0
HFD3_k127_6812693_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 463.0
HFD3_k127_6812693_3 COGs COG4299 conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000493 445.0
HFD3_k127_6812693_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 436.0
HFD3_k127_6812693_5 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002795 406.0
HFD3_k127_6812693_6 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003651 364.0
HFD3_k127_6812693_7 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004732 288.0
HFD3_k127_6812693_8 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001051 291.0
HFD3_k127_6812693_9 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001282 286.0
HFD3_k127_6828353_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05541 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 480.0
HFD3_k127_6828353_1 symporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003148 338.0
HFD3_k127_6828353_2 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000004353 59.0
HFD3_k127_6828353_3 pathogenesis - - - 0.000174 54.0
HFD3_k127_6853897_0 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 360.0
HFD3_k127_6853897_1 Domain of unknown function (DUF5122) beta-propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002892 347.0
HFD3_k127_6853897_2 receptor 98 K18263 GO:0001654,GO:0001754,GO:0001894,GO:0001895,GO:0002139,GO:0002141,GO:0002142,GO:0003008,GO:0003674,GO:0004888,GO:0004930,GO:0005488,GO:0005509,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005929,GO:0007154,GO:0007155,GO:0007165,GO:0007186,GO:0007275,GO:0007399,GO:0007423,GO:0007600,GO:0007601,GO:0007605,GO:0008092,GO:0008104,GO:0008150,GO:0009581,GO:0009582,GO:0009605,GO:0009612,GO:0009628,GO:0009653,GO:0009887,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010035,GO:0010038,GO:0010646,GO:0010647,GO:0010738,GO:0010739,GO:0016020,GO:0016021,GO:0016043,GO:0017022,GO:0022008,GO:0022610,GO:0023051,GO:0023052,GO:0023056,GO:0030030,GO:0030154,GO:0030182,GO:0031175,GO:0031224,GO:0032391,GO:0032420,GO:0032421,GO:0032501,GO:0032502,GO:0032991,GO:0033036,GO:0035869,GO:0038023,GO:0042221,GO:0042461,GO:0042462,GO:0042490,GO:0042592,GO:0042995,GO:0043005,GO:0043167,GO:0043169,GO:0043226,GO:0043235,GO:0043583,GO:0044422,GO:0044424,GO:0044425,GO:0044441,GO:0044444,GO:0044459,GO:0044463,GO:0044464,GO:0045184,GO:0045202,GO:0045494,GO:0045595,GO:0045596,GO:0046530,GO:0046872,GO:0048468,GO:0048471,GO:0048496,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048592,GO:0048666,GO:0048699,GO:0048731,GO:0048839,GO:0048856,GO:0048869,GO:0048871,GO:0050789,GO:0050793,GO:0050794,GO:0050877,GO:0050896,GO:0050906,GO:0050910,GO:0050953,GO:0050954,GO:0050974,GO:0050982,GO:0051093,GO:0051179,GO:0051234,GO:0051592,GO:0051606,GO:0051716,GO:0060089,GO:0060113,GO:0060119,GO:0060122,GO:0060249,GO:0065007,GO:0065008,GO:0070887,GO:0071241,GO:0071248,GO:0071277,GO:0071840,GO:0071944,GO:0090596,GO:0097458,GO:0097730,GO:0097731,GO:0097733,GO:0098590,GO:0098609,GO:0098858,GO:0098862,GO:0120025,GO:0120036,GO:0120038,GO:1902531,GO:1902533,GO:1990075,GO:1990696 - 0.00000002336 68.0
HFD3_k127_6855466_0 Domain of Unknown Function (DUF1080) - - - 0.0 1427.0
HFD3_k127_6855466_1 Spore coat protein CotH - - - 5.347e-263 897.0
HFD3_k127_6855466_2 peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001626 276.0
HFD3_k127_6855466_3 diaminopimelate epimerase activity K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.0000000000000000000000000000000000000000000003147 169.0
HFD3_k127_6855466_4 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000000000002252 136.0
HFD3_k127_6855466_5 HYR domain K03286 - - 0.00000000000003389 89.0
HFD3_k127_6855466_6 cellulase activity K01193 - 3.2.1.26 0.0000000000001336 87.0
HFD3_k127_6855466_7 PFAM Spore coat protein CotH - - - 0.000001424 64.0
HFD3_k127_6861453_0 response to antibiotic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005142 445.0
HFD3_k127_6861453_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000002054 85.0
HFD3_k127_6865825_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 6.132e-252 796.0
HFD3_k127_6865825_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006359 509.0
HFD3_k127_6865825_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000004163 231.0
HFD3_k127_6865825_3 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000002124 206.0
HFD3_k127_6865825_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.0000000000000000000000000000000000000000000000000000002733 201.0
HFD3_k127_6865825_5 Forms part of the polypeptide exit tunnel K02926 - - 0.0000000000000000000000000000000000000000000000001719 183.0
HFD3_k127_6865825_6 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000003772 173.0
HFD3_k127_6865825_7 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000000127 74.0
HFD3_k127_6880072_0 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 372.0
HFD3_k127_6880072_1 phosphoenolpyruvate-dependent sugar phosphotransferase system K02768,K02769,K02770,K02806 - 2.7.1.202 0.00000000000000000000000000000000000000002483 158.0
HFD3_k127_6880072_2 phosphoenolpyruvate-dependent sugar phosphotransferase system K02768,K02769,K02770,K02806 - 2.7.1.202 0.00000000000000000000000000000312 127.0
HFD3_k127_6886128_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 377.0
HFD3_k127_6886128_1 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000002604 230.0
HFD3_k127_6886128_2 Bacterial protein of unknown function (DUF883) - - - 0.0000000000001097 76.0
HFD3_k127_6886128_3 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.000001603 56.0
HFD3_k127_6901597_0 Peptidase C14 caspase catalytic subunit p20 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004867 306.0
HFD3_k127_6901597_1 Protein of unknown function (DUF455) - - - 0.000000000000000000000000000000000000000002376 166.0
HFD3_k127_6919510_0 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006439 359.0
HFD3_k127_6919510_1 domain, Protein K07654 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000005942 221.0
HFD3_k127_6921181_0 pyrroloquinoline quinone binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005379 569.0
HFD3_k127_6921181_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005965 450.0
HFD3_k127_6921181_2 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 390.0
HFD3_k127_6921181_3 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005447 325.0
HFD3_k127_6921181_4 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001063 268.0
HFD3_k127_6921181_5 CotH kinase protein - - - 0.0000000000000000000000000000000000000000004316 169.0
HFD3_k127_6934281_0 response to antibiotic - - - 0.0000000000000000000000000000000000000000007673 175.0
HFD3_k127_6934281_1 TIGRFAM autotransporter-associated beta strand repeat protein - - - 0.0000000000000000002188 100.0
HFD3_k127_6988238_0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003866 541.0
HFD3_k127_6988238_1 iron ion homeostasis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 499.0
HFD3_k127_6988238_2 PFAM Proprotein convertase P-domain - - - 0.0000000000000000000000000000000003686 153.0
HFD3_k127_6988238_3 PFAM Uncharacterised BCR, COG1649 K01179,K04618,K07346,K12685,K17734 - 1.1.3.9,3.2.1.4 0.000000008692 69.0
HFD3_k127_6988238_4 collagen metabolic process K08677 - - 0.00002593 58.0
HFD3_k127_6988238_5 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00003417 57.0
HFD3_k127_6991722_0 COG3119 Arylsulfatase A and related enzymes - - - 1.251e-198 628.0
HFD3_k127_6991722_1 Periplasmic binding protein-like domain K02058,K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006264 396.0
HFD3_k127_6991722_2 Belongs to the binding-protein-dependent transport system permease family K10440,K10559,K10561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 308.0
HFD3_k127_6991722_3 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 292.0
HFD3_k127_6991722_4 ABC transporter K02056,K05776,K10441,K10542,K10545,K10548 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000001626 218.0
HFD3_k127_6991944_0 filamentous hemagglutinin family N-terminal domain - - - 0.000000000000000000000000001308 130.0
HFD3_k127_6991944_1 Multicopper oxidase K00368,K07004 - 1.7.2.1 0.000000000000000000003999 108.0
HFD3_k127_6991944_2 - - - - 0.000000008719 69.0
HFD3_k127_6992600_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004262 599.0
HFD3_k127_6992600_1 Acetyl xylan esterase (AXE1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000002758 246.0
HFD3_k127_7003162_0 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003367 284.0
HFD3_k127_7009101_0 ASPIC UnbV domain protein - - - 5.334e-254 835.0
HFD3_k127_7009101_1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 508.0
HFD3_k127_7009101_2 Squalene phytoene synthase K00801 - 2.5.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000001757 255.0
HFD3_k127_7011829_0 Methionine synthase K00548 - 2.1.1.13 0.0 1913.0
HFD3_k127_7011829_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1406.0
HFD3_k127_7011829_10 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000002259 194.0
HFD3_k127_7011829_11 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000000000000001596 194.0
HFD3_k127_7011829_12 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000038 176.0
HFD3_k127_7011829_13 - - - - 0.00000000000000000000000000000000000000001848 175.0
HFD3_k127_7011829_14 MotA/TolQ/ExbB proton channel family K03561 - - 0.000000000000000000000000000000000000001599 155.0
HFD3_k127_7011829_15 Uncharacterized ACR, COG1678 K07735 - - 0.00000000000000000000000000000007137 132.0
HFD3_k127_7011829_16 PFAM LIM, zinc-binding protein - - - 0.000000000000001662 89.0
HFD3_k127_7011829_17 - - - - 0.000000000001316 79.0
HFD3_k127_7011829_18 calcium- and calmodulin-responsive adenylate cyclase activity K01406,K21449 - 3.4.24.40 0.0000000226 68.0
HFD3_k127_7011829_19 Biopolymer transport protein ExbD/TolR K03559 - - 0.0000005062 57.0
HFD3_k127_7011829_2 Cytochrome c - - - 5.514e-318 1007.0
HFD3_k127_7011829_3 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 8.563e-222 706.0
HFD3_k127_7011829_4 amino acid - - - 1.081e-196 631.0
HFD3_k127_7011829_5 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 515.0
HFD3_k127_7011829_6 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 465.0
HFD3_k127_7011829_7 Belongs to the TPP enzyme family K07004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004786 431.0
HFD3_k127_7011829_8 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 377.0
HFD3_k127_7011829_9 PFAM Hemolysin-type calcium-binding K01406 - 3.4.24.40 0.00000000000000000000000000000000000000000000000000000001419 227.0
HFD3_k127_7036467_0 PFAM Uncharacterised protein family UPF0027 K14415 - 6.5.1.3 2.763e-227 711.0
HFD3_k127_7036467_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002294 289.0
HFD3_k127_7036467_2 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001816 266.0
HFD3_k127_7036467_3 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000007094 189.0
HFD3_k127_7036467_4 Isochorismatase family K08281,K12132 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0018130,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0030145,GO:0034641,GO:0034654,GO:0043094,GO:0043167,GO:0043169,GO:0043173,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.11.1,3.5.1.19 0.00000000000000000000000000000000000000000002016 166.0
HFD3_k127_7036467_5 Regulatory protein, FmdB family - - - 0.000004679 56.0
HFD3_k127_7036659_0 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 458.0
HFD3_k127_7036659_1 Parallel beta-helix repeats K12287 - - 0.00000000000000000000000000000000007781 156.0
HFD3_k127_7046781_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 2.757e-250 793.0
HFD3_k127_7046781_1 Protein of unknown function (DUF3445) - - - 0.0000000000000000000000002418 111.0
HFD3_k127_7046781_2 Bacterial protein of unknown function (DUF885) - - - 0.00000005049 54.0
HFD3_k127_7071397_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 GO:0003674,GO:0003824,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016491,GO:0050896,GO:0055114 1.2.7.1 0.0 1666.0
HFD3_k127_7071397_1 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 464.0
HFD3_k127_7071397_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 400.0
HFD3_k127_7071397_3 pfkB family carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006992 392.0
HFD3_k127_7071397_4 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 318.0
HFD3_k127_7072005_0 PFAM glycoside hydrolase family 62 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000126 282.0
HFD3_k127_7072005_1 protein flavinylation K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000001641 247.0
HFD3_k127_7072005_2 PFAM tRNA rRNA methyltransferase (SpoU) - - - 0.0000000000000000000000000000000000000000664 169.0
HFD3_k127_7072005_3 Planctomycete cytochrome C - - - 0.000000000000000000000000000004207 125.0
HFD3_k127_70767_0 - - - - 0.0 1373.0
HFD3_k127_70767_1 Von Willebrand factor K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005928 621.0
HFD3_k127_70767_2 N-6 DNA Methylase - - - 0.0007315 53.0
HFD3_k127_7078186_0 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000001364 213.0
HFD3_k127_7078186_1 ABC-type uncharacterized transport system - - - 0.0000000000000000000000000000000000000001436 168.0
HFD3_k127_7078186_2 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000002441 154.0
HFD3_k127_7078186_3 Domain of unknown function (DUF4340) - - - 0.0000000000000001831 94.0
HFD3_k127_7078186_4 AsmA-like C-terminal region - - - 0.0000000000003935 84.0
HFD3_k127_7090422_0 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008522 449.0
HFD3_k127_7090422_1 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 419.0
HFD3_k127_7090422_2 peptidase activity - - - 0.000000000000000000000000000000000000000000000000003584 196.0
HFD3_k127_7090422_3 PFAM secretion protein HlyD family protein - - - 0.00000000000000000000000000000000000002862 152.0
HFD3_k127_7090422_4 - - - - 0.0000000000000000000000000000000709 139.0
HFD3_k127_7090422_5 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000118 130.0
HFD3_k127_7102044_0 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 344.0
HFD3_k127_7102044_1 ABC transporter K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002926 317.0
HFD3_k127_7102044_2 Belongs to the methyltransferase superfamily K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000306 276.0
HFD3_k127_7110202_0 TIGRFAM Por secretion system C-terminal sorting domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003897 505.0
HFD3_k127_7110202_1 Sigma-70 region 3 K02405 - - 0.00000000000000000000000000000000000000000000000000000000000000000002703 242.0
HFD3_k127_7110202_2 two component, sigma54 specific, transcriptional regulator, Fis family K07713 - - 0.00000000000000000000000000000004894 130.0
HFD3_k127_7110202_3 Prokaryotic N-terminal methylation motif - - - 0.0000000000000006595 89.0
HFD3_k127_7110202_4 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 - - 0.00000000007273 68.0
HFD3_k127_7110202_5 amine dehydrogenase activity K20276 - - 0.0000000002669 74.0
HFD3_k127_7128476_0 GMC oxidoreductase - - - 2.627e-235 739.0
HFD3_k127_7128476_1 transcription factor binding K15836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 552.0
HFD3_k127_7128476_2 Ferric reductase like transmembrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 389.0
HFD3_k127_7128476_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000002206 220.0
HFD3_k127_7128476_4 - - - - 0.0000000000000000000000000000000000000000000005808 175.0
HFD3_k127_7128476_5 - - - - 0.000000000004278 76.0
HFD3_k127_713092_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 8.969e-305 951.0
HFD3_k127_713092_1 Bacterial sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000003074 216.0
HFD3_k127_713092_2 PFAM GYD family protein - - - 0.00000000000000003301 86.0
HFD3_k127_713092_3 Signal transducing histidine kinase, homodimeric domain K02487,K03407,K06596 - 2.7.13.3 0.00000000000000007083 87.0
HFD3_k127_7133845_0 WD40-like Beta Propeller Repeat K03641 - - 2.948e-209 656.0
HFD3_k127_7133845_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 366.0
HFD3_k127_7133845_2 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002942 323.0
HFD3_k127_7133845_3 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004577 315.0
HFD3_k127_7133845_4 TIGRFAM autotransporter-associated beta strand repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000531 231.0
HFD3_k127_7133845_5 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000867 214.0
HFD3_k127_7133845_6 serine-type endopeptidase activity K14645,K20276 - - 0.000000000000000000000000000000000000000000000000004406 208.0
HFD3_k127_7133845_7 ACT domain protein - - - 0.000000000000000000000000000000000000000001094 160.0
HFD3_k127_7133845_8 Twin-arginine translocation pathway signal protein K07093 - - 0.0000000000002869 84.0
HFD3_k127_7133845_9 endonuclease I - - - 0.0000000000002947 84.0
HFD3_k127_7134815_0 Deoxyhypusine synthase K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 520.0
HFD3_k127_7134815_1 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009485 345.0
HFD3_k127_7134815_2 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004711 308.0
HFD3_k127_7134815_3 Zn-dependent protease with chaperone function - - - 0.000001057 59.0
HFD3_k127_71349_0 PFAM D-aminoacylase, C-terminal region K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007302 469.0
HFD3_k127_71349_1 beta-fructofuranosidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 407.0
HFD3_k127_71349_2 Chain length determinant protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 409.0
HFD3_k127_71349_3 Protein of unknown function (DUF819) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 344.0
HFD3_k127_71349_4 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003009 326.0
HFD3_k127_71349_5 - - - - 0.000000000000000000000000000000000000000000000000000000000005653 222.0
HFD3_k127_71349_6 O-antigen ligase like membrane protein - - - 0.0000000000000000000000000000002102 141.0
HFD3_k127_71349_7 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000001055 104.0
HFD3_k127_7143454_0 serine-type peptidase activity K08676 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 426.0
HFD3_k127_7143454_1 BNR repeat-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 365.0
HFD3_k127_7143454_2 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 301.0
HFD3_k127_7143454_3 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004357 281.0
HFD3_k127_7143454_4 R3H domain - - - 0.000000000000000000000000001162 119.0
HFD3_k127_7143454_5 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000001199 105.0
HFD3_k127_7143454_6 ribonuclease P activity K03536,K08998 GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031123,GO:0031404,GO:0031974,GO:0031981,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043628,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 0.000000002143 63.0
HFD3_k127_7143454_7 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000001187 57.0
HFD3_k127_7172987_0 PFAM Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 549.0
HFD3_k127_7172987_1 DEAD DEAH box helicase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 529.0
HFD3_k127_7172987_2 amino acid activation for nonribosomal peptide biosynthetic process K14379 - 3.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 319.0
HFD3_k127_7172987_3 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000001511 151.0
HFD3_k127_7172987_4 protein conserved in bacteria - - - 0.00000000000000000000000000000375 140.0
HFD3_k127_7172987_5 Phosphatase - GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008801,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016853,GO:0016866,GO:0016868,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872 - 0.00000000000000000000000000002055 119.0
HFD3_k127_7208282_0 Protein of unknown function (DUF3500) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 445.0
HFD3_k127_7208282_1 Competence protein K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000003794 247.0
HFD3_k127_7210077_0 COG3119 Arylsulfatase A K01130 - 3.1.6.1 2.881e-231 732.0
HFD3_k127_7210077_1 Sulfotransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002486 246.0
HFD3_k127_7210077_2 calcium- and calmodulin-responsive adenylate cyclase activity K03651 - 3.1.4.53 0.0000000000000000000000000000000000000008865 172.0
HFD3_k127_7210077_3 Hep Hag repeat protein - - - 0.000000000000000000001623 99.0
HFD3_k127_7210077_4 hydrolase, family 65, central catalytic K21302 - 3.1.3.64 0.000009092 60.0
HFD3_k127_7224427_0 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005719 420.0
HFD3_k127_7224427_1 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000007968 259.0
HFD3_k127_7224427_2 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion K02564 - 3.5.99.6 0.0000000000000000000000000000000000000007205 169.0
HFD3_k127_7224427_3 EamA-like transporter family - - - 0.00000000000000000000001229 113.0
HFD3_k127_7224427_4 InterPro IPR007367 - - - 0.000000000000000000002268 100.0
HFD3_k127_7231161_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.0 1299.0
HFD3_k127_7231161_1 Planctomycete cytochrome C - - - 3.435e-303 960.0
HFD3_k127_7231161_10 Glycosyl hydrolase family 92 - - - 0.00000000000000000003461 109.0
HFD3_k127_7231161_11 Lamin Tail Domain - - - 0.00000003743 69.0
HFD3_k127_7231161_12 Protein of unknown function (DUF1553) - - - 0.000002243 57.0
HFD3_k127_7231161_2 Protein of unknown function (DUF1501) - - - 1.803e-238 749.0
HFD3_k127_7231161_3 CotH kinase protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004621 670.0
HFD3_k127_7231161_4 Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 524.0
HFD3_k127_7231161_5 Transcriptional regulator K21703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005069 358.0
HFD3_k127_7231161_6 PFAM regulatory protein LuxR - - - 0.000000000000000000000000000000000000000000000000000000000000005575 227.0
HFD3_k127_7231161_7 NnrS protein - - - 0.00000000000000000000000000000000000000000000000000000000000006578 235.0
HFD3_k127_7231161_8 Planctomycete cytochrome C - - - 0.0000000000000000000000000000000000002973 164.0
HFD3_k127_7231161_9 Spore coat protein CotH - - - 0.000000000000000000000000000000001181 153.0
HFD3_k127_7267984_0 Endoribonuclease that initiates mRNA decay K18682 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 477.0
HFD3_k127_7267984_1 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 381.0
HFD3_k127_7267984_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 330.0
HFD3_k127_7267984_3 PFAM peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003596 259.0
HFD3_k127_7267984_4 5-formyltetrahydrofolate cyclo-ligase family K01934 GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0030272,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 0.0000000000000000000000001893 115.0
HFD3_k127_7267984_5 nuclear chromosome segregation - - - 0.00000005209 63.0
HFD3_k127_7267984_6 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 0.00002533 48.0
HFD3_k127_7290374_0 asparagine synthase K01953 - 6.3.5.4 3.138e-213 690.0
HFD3_k127_7290374_1 Elongator protein 3, MiaB family, Radical SAM K06936 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 368.0
HFD3_k127_7290374_2 CotH kinase protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002887 282.0
HFD3_k127_7290374_3 Domain of unknown function (DUF4982) - - - 0.00000000000000000000001225 117.0
HFD3_k127_7290374_4 geranylgeranyl reductase activity K14257 - 1.14.19.49 0.000000000000000002238 87.0
HFD3_k127_7294012_0 Spore coat protein CotH K01216,K07004 - 3.2.1.73 5.256e-240 812.0
HFD3_k127_7294012_1 C-terminal PDZ domain K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007217 280.0
HFD3_k127_7294012_2 response to antibiotic - - - 0.0000000000000000000000000001223 136.0
HFD3_k127_7294012_3 - - - - 0.00000000000000000000000001049 127.0
HFD3_k127_7294012_4 CotH kinase protein - - - 0.00000000008086 77.0
HFD3_k127_7294012_5 PFAM Fibronectin type III domain - - - 0.0000000005543 74.0
HFD3_k127_7294012_6 Pectate lyase K01732,K20276 - 4.2.2.10 0.0000000006448 74.0
HFD3_k127_7294012_7 alginic acid biosynthetic process K01729,K17713 - 4.2.2.3 0.00000007822 67.0
HFD3_k127_7294012_8 Right handed beta helix region - - - 0.00001452 59.0
HFD3_k127_7298744_0 Cytochrome C oxidase, cbb3-type, subunit III - - - 4.509e-199 645.0
HFD3_k127_7298744_1 carbohydrate kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 556.0
HFD3_k127_7298744_2 N-acetylglucosaminylinositol deacetylase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007255 307.0
HFD3_k127_7298744_3 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000117 292.0
HFD3_k127_7298744_4 chitin catabolic process K02358,K15924 - 3.2.1.136 0.000006442 59.0
HFD3_k127_7315592_0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 421.0
HFD3_k127_7315592_1 Phosphomannose isomerase type I K01809 - 5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004632 312.0
HFD3_k127_7315592_2 3'-5' exonuclease K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000001413 250.0
HFD3_k127_7315592_3 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.000000000000000000000000000000000000000002921 163.0
HFD3_k127_7315592_4 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.00000000000002504 81.0
HFD3_k127_7317337_0 peptidyl-tyrosine sulfation - - - 1.94e-239 767.0
HFD3_k127_7317337_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005021 613.0
HFD3_k127_7317337_2 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 380.0
HFD3_k127_7317337_3 Ribosomal small subunit Rsm22 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006154 314.0
HFD3_k127_7317337_4 Transposase IS200 like - - - 0.000000000000000000000000000000000000000000000000002545 194.0
HFD3_k127_7317337_5 SCO1/SenC K07152 - - 0.000000000000000000000000000000000000000000000000008151 194.0
HFD3_k127_7317337_6 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000159 106.0
HFD3_k127_7317337_7 PFAM Spore coat protein CotH - - - 0.0000000000000006273 92.0
HFD3_k127_7317337_8 Glycosyl hydrolases family 18 K01183 - 3.2.1.14 0.00002951 55.0
HFD3_k127_733440_0 Protein of unknown function (DUF1501) - - - 1.45e-226 710.0
HFD3_k127_733440_1 Planctomycete cytochrome C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008695 462.0
HFD3_k127_7338433_0 L-lactate permease K03303 - - 1.745e-222 702.0
HFD3_k127_7338433_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 335.0
HFD3_k127_7338433_2 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000004408 246.0
HFD3_k127_7338433_3 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000888 156.0
HFD3_k127_7338433_5 xyloglucan:xyloglucosyl transferase activity - - - 0.0000000000000000000002904 112.0
HFD3_k127_7338433_6 Involved in resistance toward heavy metals K03926 GO:0003674,GO:0005488,GO:0005507,GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0016043,GO:0022607,GO:0042221,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0046688,GO:0046872,GO:0046914,GO:0050896,GO:0051259,GO:0051260,GO:0065003,GO:0071840 - 0.000000000000000000014 107.0
HFD3_k127_7338433_7 MraZ protein, putative antitoxin-like K03925 - - 0.00000000000000001431 88.0
HFD3_k127_7354439_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 9.205e-273 852.0
HFD3_k127_7354439_1 cell wall glycoprotein biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 507.0
HFD3_k127_7354439_2 amino acid peptide transporter K03305 - - 0.000000000000000000000000000001886 123.0
HFD3_k127_7354634_0 cytochrome - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 332.0
HFD3_k127_7354634_1 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000001386 185.0
HFD3_k127_7354634_2 Methyltransferase domain - - - 0.0000000000000000003703 96.0
HFD3_k127_7354634_3 - - - - 0.0002511 49.0
HFD3_k127_7370120_0 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 508.0
HFD3_k127_7370120_1 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 514.0
HFD3_k127_7370120_2 Beta-lactamase class C - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 426.0
HFD3_k127_7370120_3 SIS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 390.0
HFD3_k127_7370120_4 Putative esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007218 377.0
HFD3_k127_7370120_5 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 337.0
HFD3_k127_7370120_6 PQQ-like domain - - - 0.0000000000000000000000000007558 116.0
HFD3_k127_7383191_0 - - - - 0.0 1975.0
HFD3_k127_7383191_1 Pectate lyase K01179,K01406,K21449 - 3.2.1.4,3.4.24.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 512.0
HFD3_k127_7383191_2 domain, Protein K01406,K15125 - 3.4.24.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004554 307.0
HFD3_k127_7383191_3 peptidyl-prolyl cis-trans isomerase activity K03769,K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000003672 183.0
HFD3_k127_739637_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000003324 186.0
HFD3_k127_739637_1 helix_turn_helix gluconate operon transcriptional repressor K07979 - - 0.00000000000000000002448 96.0
HFD3_k127_739637_2 Regulator of chromosome condensation (RCC1) repeat - - - 0.0000000002053 74.0
HFD3_k127_7438082_0 Periplasmic binding proteins and sugar binding domain of LacI family K10439,K10552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000551 385.0
HFD3_k127_7438082_1 transport system, ATPase K10441 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000007028 208.0
HFD3_k127_7438082_2 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.000000000000000000000000000000000000000000000002267 187.0
HFD3_k127_7438082_3 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.000000000000000003123 100.0
HFD3_k127_7438868_0 PFAM Glucose Sorbosone dehydrogenase K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006404 436.0
HFD3_k127_7438868_1 Copper binding periplasmic protein CusF K07152 - - 0.000000000000000000000000000000000000000003499 168.0
HFD3_k127_747097_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1136.0
HFD3_k127_747097_1 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009271 289.0
HFD3_k127_747097_10 RDD family K18481 - - 0.000000008815 66.0
HFD3_k127_747097_11 Domain of unknown function (DUF4190) - - - 0.000001077 61.0
HFD3_k127_747097_12 RDD family K18481 - - 0.000004396 59.0
HFD3_k127_747097_2 Quinolinate phosphoribosyl transferase, N-terminal domain K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000006341 271.0
HFD3_k127_747097_3 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000626 259.0
HFD3_k127_747097_4 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000004588 248.0
HFD3_k127_747097_5 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000001036 235.0
HFD3_k127_747097_6 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000001451 209.0
HFD3_k127_747097_7 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000362 168.0
HFD3_k127_747097_8 protein conserved in bacteria - - - 0.0000000000000000000000000000000000002161 159.0
HFD3_k127_747097_9 integral membrane protein - - - 0.00000000000000000000000000000002748 138.0
HFD3_k127_7497096_0 self proteolysis - - - 0.00000000000000000000000001311 129.0
HFD3_k127_7497096_1 PhoD-like phosphatase - - - 0.00000000007843 77.0
HFD3_k127_7497708_0 ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008603 434.0
HFD3_k127_7497708_1 PFAM ATP-binding region, ATPase domain protein domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000887 335.0
HFD3_k127_7497708_2 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000002173 205.0
HFD3_k127_7497708_3 Histidine biosynthesis protein K01814 - 5.3.1.16 0.0000000000000000000000000000000000002034 147.0
HFD3_k127_753900_0 CotH kinase protein - - - 0.00000000000000000000000000000000000002676 165.0
HFD3_k127_753900_1 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K07093 - - 0.00000000000002458 87.0
HFD3_k127_7550195_0 Cytochrome b/b6/petB K00412 - - 5.41e-222 722.0
HFD3_k127_7550195_1 Uncharacterized conserved protein (DUF2183) - - - 0.00000000000000000000000000000000000000000000000000000000005505 230.0
HFD3_k127_7572999_0 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 515.0
HFD3_k127_7572999_1 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006642 351.0
HFD3_k127_7604333_0 Pkd domain containing protein - - - 0.00000000000000000000000000000000000000006925 163.0
HFD3_k127_7604333_1 Required for transformation and DNA binding K02245,K02456 GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000003051 88.0
HFD3_k127_7608549_0 Polysulphide reductase, NrfD K00185 - - 8.873e-214 672.0
HFD3_k127_7608549_1 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003297 462.0
HFD3_k127_7608549_2 Cytochrome C and Quinol oxidase polypeptide I K00404 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 348.0
HFD3_k127_7608549_3 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003061 270.0
HFD3_k127_7608549_4 Protein of unknown function (DUF3341) - - - 0.000000000000000000000000000000000000000000000000003356 204.0
HFD3_k127_7608549_5 Cytochrome c - - - 0.00000000000000000000000000000000000000000009471 168.0
HFD3_k127_7608549_6 cytochrome c oxidase K00405 - - 0.0000000000000000001424 96.0
HFD3_k127_7608549_7 - - - - 0.0000007169 56.0
HFD3_k127_7660553_0 Alpha-L-rhamnosidase N-terminal domain K05989 - 3.2.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 415.0
HFD3_k127_7660553_1 Cna protein B-type domain - - - 0.0000000000000000000004374 113.0
HFD3_k127_7660553_2 Glucose / Sorbosone dehydrogenase K21430 - - 0.000004792 61.0
HFD3_k127_7660553_3 mandelate racemase muconate lactonizing K08323 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0008150,GO:0008152,GO:0008927,GO:0009056,GO:0016052,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0044238,GO:0046872,GO:0071704,GO:1901575 4.2.1.8 0.0005102 43.0
HFD3_k127_7689387_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 4.912e-242 771.0
HFD3_k127_7689387_1 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 492.0
HFD3_k127_7689387_10 - - - - 0.00000000000000000000000000000001107 139.0
HFD3_k127_7689387_11 GtrA-like protein - - - 0.000000005452 67.0
HFD3_k127_7689387_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 450.0
HFD3_k127_7689387_3 tryptophan synthase activity K01696,K06001 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000511 410.0
HFD3_k127_7689387_4 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003573 311.0
HFD3_k127_7689387_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002917 269.0
HFD3_k127_7689387_6 NAD dependent epimerase dehydratase family protein K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000333 248.0
HFD3_k127_7689387_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000002455 239.0
HFD3_k127_7689387_8 MOSC domain - - - 0.0000000000000000000000000000000000000000000000000004861 190.0
HFD3_k127_7689387_9 - - - - 0.0000000000000000000000000000000000000002834 155.0
HFD3_k127_7703097_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004529 372.0
HFD3_k127_7703097_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 341.0
HFD3_k127_7703097_2 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.00000000000000000000000000000000000000000000000000000000000004287 224.0
HFD3_k127_7703097_3 NUDIX hydrolase K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000134 163.0
HFD3_k127_7704308_0 Aminotransferase class I and II K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 409.0
HFD3_k127_7704308_1 DRTGG domain K06873 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003853 409.0
HFD3_k127_7704308_2 Beta-lactamase class C - - - 0.0000000000000000000000000000000000000000000000000000000000113 213.0
HFD3_k127_7704308_3 PFAM phosphate acetyl butaryl transferase K00625,K13788 - 2.3.1.8 0.000000000000000000000000000000000044 136.0
HFD3_k127_7712851_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009133 496.0
HFD3_k127_7712851_1 phosphoesterase RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000009679 205.0
HFD3_k127_7712851_2 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.0000000000000000000000000000000000000002463 157.0
HFD3_k127_7712851_3 Glycogen recognition site of AMP-activated protein kinase - - - 0.0000000000000009905 84.0
HFD3_k127_7712851_4 SMART ATP-binding region ATPase domain protein K03406,K07710 - 2.7.13.3 0.0001086 45.0
HFD3_k127_7735234_0 Belongs to the MIP aquaporin (TC 1.A.8) family K02440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003491 349.0
HFD3_k127_7735234_1 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 341.0
HFD3_k127_7735234_2 deoxyhypusine monooxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000004101 203.0
HFD3_k127_7735234_3 NAD(P)H-binding - - - 0.000000000000000000000000000000000000000000000000002164 195.0
HFD3_k127_7735234_4 Histidine phosphatase superfamily (branch 1) - - - 0.000000000000000000000000000000000000001568 157.0
HFD3_k127_773627_0 PFAM oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 513.0
HFD3_k127_773627_1 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003454 385.0
HFD3_k127_773627_2 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000001857 158.0
HFD3_k127_7736728_0 Pyruvate phosphate dikinase - - - 0.000000000000000000000000000002911 133.0
HFD3_k127_7736728_1 protein N-acetylglucosaminyltransferase activity - - - 0.000000000000000000000593 107.0
HFD3_k127_7736728_2 belongs to the thioredoxin family K03671,K05838 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000005392 77.0
HFD3_k127_774431_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004154 434.0
HFD3_k127_774431_1 protein containing a von Willebrand factor type A (vWA) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 387.0
HFD3_k127_774431_2 - - - - 0.000000000000000000000000000000002139 138.0
HFD3_k127_774431_3 protein containing a von Willebrand factor type A (vWA) domain - - - 0.00000009682 56.0
HFD3_k127_7747540_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 6.802e-205 666.0
HFD3_k127_7747540_1 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000695 482.0
HFD3_k127_7747540_2 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 361.0
HFD3_k127_7747540_3 DHHA1 domain K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000001548 275.0
HFD3_k127_7747540_4 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000002632 249.0
HFD3_k127_7747540_5 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000008206 211.0
HFD3_k127_7747540_6 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000004121 86.0
HFD3_k127_7747540_7 protein conserved in bacteria - - - 0.0003218 53.0
HFD3_k127_778403_0 MMPL family K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000002736 257.0
HFD3_k127_778403_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000002597 199.0
HFD3_k127_781977_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 8.101e-197 642.0
HFD3_k127_781977_1 Dystroglycan-type cadherin-like domains. - - - 0.000000000000000000000000000000009766 147.0
HFD3_k127_781977_2 iron ion homeostasis K04758 GO:0000041,GO:0006810,GO:0006811,GO:0006812,GO:0006826,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0015684,GO:0030001,GO:0033554,GO:0034220,GO:0034755,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070627,GO:0070838,GO:0072511,GO:0097286,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098707,GO:0098711,GO:0098739,GO:0099587,GO:1903874 - 0.000000000000000007942 88.0
HFD3_k127_781977_3 PFAM blue (type 1) copper domain protein - - - 0.0000004136 58.0
HFD3_k127_781977_4 FeoA domain - - - 0.000003319 56.0
HFD3_k127_788128_0 transmembrane signaling receptor activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004521 391.0
HFD3_k127_788128_1 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.000000000000000016 82.0
HFD3_k127_788474_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 582.0
HFD3_k127_788474_1 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005043 275.0
HFD3_k127_788474_2 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006398 276.0
HFD3_k127_788474_3 ECF sigma factor K03088 - - 0.000000000000000000000000000000000000000000000000000000002131 207.0
HFD3_k127_788474_4 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.0000000000000000000000000000000000000008127 166.0
HFD3_k127_788474_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.000000000000000000000000000000006012 132.0
HFD3_k127_79729_0 PFAM peptidase S8 and S53 subtilisin kexin sedolisin K08651 - 3.4.21.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 321.0
HFD3_k127_79729_1 LytB protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000008811 238.0
HFD3_k127_79729_2 - - - - 0.000000000000000000000000000000000000000000000000209 185.0
HFD3_k127_79729_3 sulfuric ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000001152 182.0
HFD3_k127_79729_4 sulfuric ester hydrolase activity - - - 0.0000000000000000000000000000000000000008406 157.0
HFD3_k127_79729_5 Protein of unknown function (DUF1361) - - - 0.00000000000000000000000000000001599 136.0
HFD3_k127_79729_6 Transcriptional regulator - - - 0.000000000000000000002797 105.0
HFD3_k127_79729_7 - - - - 0.00000000096 67.0
HFD3_k127_797315_0 amino acid activation for nonribosomal peptide biosynthetic process - - - 2.023e-211 670.0
HFD3_k127_797315_1 ammonium transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 557.0
HFD3_k127_797315_10 - - - - 0.00000000000245 78.0
HFD3_k127_797315_2 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006299 489.0
HFD3_k127_797315_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004556 398.0
HFD3_k127_797315_4 Type IV leader peptidase family K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007024 320.0
HFD3_k127_797315_5 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000005925 267.0
HFD3_k127_797315_6 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000005009 213.0
HFD3_k127_797315_7 Belongs to the P(II) protein family - - - 0.00000000000000000000000000000000000000000000000000002225 189.0
HFD3_k127_797315_8 c-di-gmp phosphodiesterase - - - 0.0000000000000000000000000000000000002015 165.0
HFD3_k127_797315_9 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000000000007426 111.0
HFD3_k127_799025_0 Nucleoside H+ symporter - - - 1.308e-200 634.0
HFD3_k127_799025_1 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000003391 140.0
HFD3_k127_799025_2 Type II secretion system (T2SS), protein F - - - 0.000000000000000000000000002284 124.0
HFD3_k127_799025_3 Xylose isomerase-like TIM barrel - - - 0.00000000000000003878 88.0
HFD3_k127_799435_0 Type II secretion system (T2SS), protein K - - - 0.000000000000000000000000000000001396 147.0
HFD3_k127_799435_1 Type II secretion system (T2SS), protein G K02456 - - 0.00000000000000000000000000000007571 131.0
HFD3_k127_799435_2 Type II secretion system (T2SS), protein J K02459 - - 0.000001762 61.0
HFD3_k127_799435_3 protein transport across the cell outer membrane K02457,K08084 - - 0.000002148 60.0
HFD3_k127_83520_0 PFAM MgtE intracellular K02383 - - 1.322e-230 777.0
HFD3_k127_83520_1 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 575.0
HFD3_k127_83520_10 NIL domain - - - 0.000000000000000000000002274 107.0
HFD3_k127_83520_11 PFAM Prenyltransferase squalene oxidase - - - 0.00006578 57.0
HFD3_k127_83520_2 Hemolysin-type calcium-binding repeat (2 copies) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 401.0
HFD3_k127_83520_4 coenzyme binding K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007163 321.0
HFD3_k127_83520_5 asparaginase K13051 - 3.4.19.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004951 313.0
HFD3_k127_83520_6 conserved protein (COG2071) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003616 253.0
HFD3_k127_83520_7 MarR family - - - 0.000000000000000000000000000000000000000000000000000000000000001769 228.0
HFD3_k127_83520_8 Molybdopterin converting factor, small subunit K03636 - - 0.0000000000000000000000000000006257 123.0
HFD3_k127_83520_9 Protein of Unknown function (DUF2784) - - - 0.0000000000000000000000000001951 123.0
HFD3_k127_839360_0 with different specificities (related to short-chain alcohol - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004758 326.0
HFD3_k127_839360_1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000001825 212.0
HFD3_k127_839360_2 CotH kinase protein - - - 0.000000000000000000000000000000000000000000000000000004378 211.0
HFD3_k127_844272_0 CARDB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004585 646.0
HFD3_k127_844272_1 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000006421 119.0
HFD3_k127_844272_2 Belongs to the TPP enzyme family K01637 - 4.1.3.1 0.0000000000000005135 96.0
HFD3_k127_844272_3 Protein of unknown function (DUF1349) - - - 0.00000000000001046 91.0
HFD3_k127_844272_4 domain, Protein - - - 0.0000007486 65.0
HFD3_k127_844272_5 Belongs to the glycosyl hydrolase 2 family - - - 0.0003107 57.0
HFD3_k127_845798_0 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007479 328.0
HFD3_k127_845798_1 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000137 246.0
HFD3_k127_845798_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000001073 179.0
HFD3_k127_845798_3 CotH kinase protein - - - 0.00000000000004168 87.0
HFD3_k127_845798_4 Type IV pilus assembly protein PilM K02662 - - 0.00000000001677 76.0
HFD3_k127_845798_5 Pilus assembly protein, PilO K02664 - - 0.00001416 54.0
HFD3_k127_851612_0 Sulfatase - - - 9.746e-256 799.0
HFD3_k127_851612_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005937 487.0
HFD3_k127_851612_10 - - - - 0.000001371 58.0
HFD3_k127_851612_2 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 344.0
HFD3_k127_851612_3 DAHP synthetase I family K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 337.0
HFD3_k127_851612_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 329.0
HFD3_k127_851612_5 lipopolysaccharide transport protein B ATP-binding component of ABC superfamily K01990,K06861 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 310.0
HFD3_k127_851612_6 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.000000000000000000000000000000000003816 147.0
HFD3_k127_851612_7 - K07341 - - 0.000000000000000000000000000000000217 139.0
HFD3_k127_851612_8 PFAM outer membrane efflux protein - - - 0.000000000000000000000000002671 130.0
HFD3_k127_859437_0 Glucose / Sorbosone dehydrogenase - - - 0.0 1073.0
HFD3_k127_859437_1 MMPL family - - - 2.006e-233 753.0
HFD3_k127_859437_2 Putative glucoamylase - - - 0.0000000000000000000000000000000000000000000000000000000000004141 213.0
HFD3_k127_859437_3 HlyD family secretion protein K03585,K07799 - - 0.000000000000000000000000000000000000000000000000000000000002164 224.0
HFD3_k127_863675_0 Cytochrome c - - - 3.2e-322 1013.0
HFD3_k127_886882_0 4Fe-4S single cluster domain - - - 3.694e-197 627.0
HFD3_k127_886882_1 lipoprotein biosynthetic process K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003828 281.0
HFD3_k127_890163_0 L-seryl-tRNASec selenium transferase activity K01042 GO:0003674,GO:0003824,GO:0004125,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0090304,GO:0097056,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005271 409.0
HFD3_k127_890163_1 Domain of unknown function (DUF5122) beta-propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 331.0
HFD3_k127_890163_2 selenide, water dikinase activity K01008,K04487 - 2.7.9.3,2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001591 274.0
HFD3_k127_890163_3 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000002192 248.0
HFD3_k127_890163_4 Belongs to the peptidase S8 family K14645 GO:0005575,GO:0005576 - 0.0000000000000000000000000000000000000000000000000000003125 224.0
HFD3_k127_890163_5 PFAM Proprotein convertase P-domain - - - 0.0000000000000000000000000000000000000000000000184 198.0
HFD3_k127_890163_6 guanyl-nucleotide exchange factor activity K20276 - - 0.00000001513 70.0
HFD3_k127_904735_0 serine-type peptidase activity K01278 - 3.4.14.5 2.968e-291 910.0
HFD3_k127_904735_1 von Willebrand factor (vWF) type A domain - - - 1.55e-272 861.0
HFD3_k127_904735_2 dehydrogenases and related proteins - - - 2.988e-213 671.0
HFD3_k127_904735_3 translation initiation factor activity K01448,K07315,K21470 - 3.1.3.3,3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 381.0
HFD3_k127_904735_4 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 352.0
HFD3_k127_904735_5 bacterial-type flagellum-dependent cell motility K15923 - 3.2.1.51 0.00000000000000000000000000000000000000000000000000000000002687 213.0
HFD3_k127_923007_0 PFAM Prenyltransferase squalene oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007031 377.0
HFD3_k127_923007_2 PA14 - - - 0.0000000000000000000000000000000000000000001055 180.0
HFD3_k127_923007_3 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.000000000000000000000000000000002436 134.0
HFD3_k127_923007_4 Domain of unknown function (DUF5069) - - - 0.0000000000000004033 84.0
HFD3_k127_927556_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism - - - 3.036e-253 799.0
HFD3_k127_927556_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K02887,K03628 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000351 273.0
HFD3_k127_935597_0 Protein of unknown function (DUF1549) - - - 2.14e-276 871.0
HFD3_k127_942859_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005055 497.0
HFD3_k127_942859_1 COG0657 Esterase lipase - - - 0.00000000000000000000000000000000000000000001332 180.0
HFD3_k127_942859_2 PHP domain protein - - - 0.0000000000000000000000000000000000000009105 165.0
HFD3_k127_942859_3 VTC domain - - - 0.000000000000000000000001847 113.0
HFD3_k127_945351_0 COG1082 Sugar phosphate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005877 284.0
HFD3_k127_945351_1 PFAM aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000003433 238.0
HFD3_k127_945351_2 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000001684 244.0
HFD3_k127_945351_3 Transcriptional regulatory protein, C terminal K02483 - - 0.00000000000000000805 91.0
HFD3_k127_945351_4 cheY-homologous receiver domain - - - 0.0000000000000007536 87.0
HFD3_k127_945351_5 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657 - - 0.0000000000000007536 87.0
HFD3_k127_945351_6 tetratricopeptide repeat - - - 0.0000000002226 66.0
HFD3_k127_952531_0 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005638 552.0
HFD3_k127_952531_1 Thiazole biosynthesis protein ThiG K03149 - 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 426.0
HFD3_k127_952531_2 PFAM peptidase M16 domain protein K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000033 433.0
HFD3_k127_952531_3 Putative aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002931 312.0
HFD3_k127_952531_4 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 291.0
HFD3_k127_952531_5 Cupin 2, conserved barrel domain protein - - - 0.0004055 49.0
HFD3_k127_977616_0 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 341.0
HFD3_k127_977616_1 alginic acid biosynthetic process K09483 - 4.2.1.118 0.00000000000009995 85.0
HFD3_k127_977616_2 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0002379 54.0
HFD3_k127_99994_0 peptidyl-tyrosine sulfation - - - 1.774e-315 1000.0
HFD3_k127_99994_1 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004174 567.0
HFD3_k127_99994_2 COG3119 Arylsulfatase A K01138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 543.0
HFD3_k127_99994_3 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004839 440.0
HFD3_k127_99994_4 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002382 251.0
HFD3_k127_99994_5 Cytochrome c - - - 0.0002898 49.0