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Overview

ID MAG01680
Name HFD3_bin.19
Sample SMP0045
Taxonomy
Kingdom Bacteria
Phylum Chloroflexota
Class Anaerolineae
Order UBA4142
Family UBA4142
Genus JACQYF01
Species
Assembly information
Completeness (%) 81.15
Contamination (%) 4.58
GC content (%) 57.0
N50 (bp) 7,481
Genome size (bp) 4,150,441

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3893

Gene name Description KEGG GOs EC E-value Score Sequence
HFD3_k127_1000591_0 carbohydrate transport K02027,K05813 - - 0.0000000000000000000000000000000000000000001203 178.0
HFD3_k127_1000591_1 carbohydrate transport K02027,K05813 - - 0.0000000000000000000000000000000000000002744 167.0
HFD3_k127_1000591_2 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000001238 117.0
HFD3_k127_1013407_0 Stage II sporulation E family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006382 299.0
HFD3_k127_1013407_1 PFAM glycoside hydrolase, family 3 domain protein K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009796 268.0
HFD3_k127_1013407_2 SMART protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000201 207.0
HFD3_k127_1013407_3 Tetratricopeptide repeat - - - 0.000001301 51.0
HFD3_k127_1015686_0 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003397 459.0
HFD3_k127_1015686_1 Aminoglycoside phosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004472 424.0
HFD3_k127_1015686_2 histidine kinase HAMP region domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 342.0
HFD3_k127_1016576_0 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 1.372e-223 712.0
HFD3_k127_1016576_1 ABC-type dipeptide transport system periplasmic component K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009154 617.0
HFD3_k127_1016576_10 Protein of unknown function (DUF917) K09703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007719 301.0
HFD3_k127_1016576_11 COG3039 Transposase and inactivated derivatives, IS5 family K07481 - - 0.00000000000000000000000000000000000000000000012 179.0
HFD3_k127_1016576_12 Transposase K07481 - - 0.00000000000000000000000000000000000598 149.0
HFD3_k127_1016576_13 competence protein COMEC K02238 - - 0.00009573 49.0
HFD3_k127_1016576_2 intracellular signal transduction - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 567.0
HFD3_k127_1016576_3 PFAM Hydantoinase B oxoprolinase K01469,K01474 - 3.5.2.14,3.5.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006439 544.0
HFD3_k127_1016576_4 transposition K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006053 433.0
HFD3_k127_1016576_5 Oligopeptide/dipeptide transporter, C-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006741 421.0
HFD3_k127_1016576_6 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008002 417.0
HFD3_k127_1016576_7 Protein of unknown function (DUF1177) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 396.0
HFD3_k127_1016576_8 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 366.0
HFD3_k127_1016576_9 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006129 309.0
HFD3_k127_1020452_0 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006452 291.0
HFD3_k127_1020452_1 organic phosphonate transport K02044 - - 0.00000000000000000000000000000000000000000000000000005832 204.0
HFD3_k127_1020452_2 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.00000000000000000000000000000000000000000002083 165.0
HFD3_k127_1025969_0 malic protein domain protein K00027,K00029 - 1.1.1.38,1.1.1.40 1.926e-297 932.0
HFD3_k127_1025969_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.0000000000000000000000000000000000000000000001597 171.0
HFD3_k127_1025969_2 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000006957 170.0
HFD3_k127_1025969_4 - - - - 0.0002533 49.0
HFD3_k127_10275_0 Bacterial transcriptional activator domain - - - 2.949e-300 955.0
HFD3_k127_10275_1 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008105 276.0
HFD3_k127_10275_2 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005616 269.0
HFD3_k127_10275_3 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000005842 209.0
HFD3_k127_10275_4 Belongs to the UPF0306 family K09979 - - 0.00000000000000000000000001119 115.0
HFD3_k127_10275_5 NUDIX domain - - - 0.00000001311 61.0
HFD3_k127_10275_6 SMART extracellular solute-binding protein family 3 K02051 - - 0.00001242 49.0
HFD3_k127_1029125_0 NTF2-like N-terminal transpeptidase domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001222 282.0
HFD3_k127_1029125_1 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000001458 170.0
HFD3_k127_1029125_2 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000000000000000000000000000006127 127.0
HFD3_k127_103872_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008494 619.0
HFD3_k127_103872_1 PFAM PKD domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 378.0
HFD3_k127_103872_2 metallophosphoesterase K07096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000032 323.0
HFD3_k127_103872_3 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005882 318.0
HFD3_k127_103872_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000136 287.0
HFD3_k127_103872_5 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro K01101,K02566 - 3.1.3.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002206 282.0
HFD3_k127_103872_6 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000005141 186.0
HFD3_k127_1039751_0 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 326.0
HFD3_k127_1039751_1 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 0.00000000000000000000000000000000000000000000004021 176.0
HFD3_k127_1043170_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006052 373.0
HFD3_k127_1043170_1 PFAM Roadblock LC7 family protein K07131 - - 0.00000000000000000000000000000000000000000004711 164.0
HFD3_k127_1043170_2 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000003196 170.0
HFD3_k127_1043170_3 Aldo/keto reductase family K05882 - 1.1.1.91 0.000004639 51.0
HFD3_k127_1046901_0 MacB-like periplasmic core domain K02004 - - 1.617e-195 638.0
HFD3_k127_1046901_1 ABC transporter related K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005983 414.0
HFD3_k127_1046901_2 response regulator, receiver K02479 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001008 253.0
HFD3_k127_1046901_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000002371 182.0
HFD3_k127_1046901_4 helix_turn_helix, Lux Regulon - - - 0.000000000000001618 82.0
HFD3_k127_1050758_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K00058,K03977 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007736 500.0
HFD3_k127_1050758_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006357 274.0
HFD3_k127_1050758_2 - - - - 0.000000000001842 76.0
HFD3_k127_1050758_3 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000006263 54.0
HFD3_k127_1054866_0 cellulose binding - - - 0.000000000000000000000000000000000000000000000189 180.0
HFD3_k127_1054866_1 Predicted membrane protein (DUF2085) - - - 0.00000000000000851 79.0
HFD3_k127_1054866_2 - - - - 0.00000000000004248 79.0
HFD3_k127_1054866_3 zinc-ribbon domain - - - 0.00004127 47.0
HFD3_k127_1071389_0 PFAM peptidase M48 Ste24p K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 371.0
HFD3_k127_1071389_1 short-chain dehydrogenase reductase SDR K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 350.0
HFD3_k127_1071389_10 lipid binding - - - 0.00000000000000000000000000000000000000000000000000000000004854 214.0
HFD3_k127_1071389_11 HD domain - - - 0.00000000000000000000000000000000000000000000000000000001324 201.0
HFD3_k127_1071389_12 XdhC and CoxI family - - - 0.00000000000000000000000000000000000003307 145.0
HFD3_k127_1071389_13 MFS_1 like family - - - 0.0000000000000000000000000000000000002424 156.0
HFD3_k127_1071389_14 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000000000000007518 118.0
HFD3_k127_1071389_15 LysM domain K03642,K03791,K22278 - 3.5.1.104 0.00000000000000000828 90.0
HFD3_k127_1071389_16 PBS lyase HEAT domain protein repeat-containing protein K22221 - - 0.00000000003972 74.0
HFD3_k127_1071389_17 DinB superfamily - - - 0.00000009159 60.0
HFD3_k127_1071389_18 peptidase activity - - - 0.0000001228 61.0
HFD3_k127_1071389_2 NAD synthase K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 337.0
HFD3_k127_1071389_3 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003904 332.0
HFD3_k127_1071389_4 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 296.0
HFD3_k127_1071389_5 AMP-binding enzyme K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000008388 265.0
HFD3_k127_1071389_6 XdhC Rossmann domain K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000003416 243.0
HFD3_k127_1071389_7 PFAM DegV family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000003732 236.0
HFD3_k127_1071389_8 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000001569 228.0
HFD3_k127_1071389_9 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000001477 226.0
HFD3_k127_1088383_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 1.471e-207 652.0
HFD3_k127_1088383_1 Purine catabolism regulatory protein-like family K09684 - - 0.000000000000000000000000000000000000002818 153.0
HFD3_k127_1091527_0 Pyridine nucleotide-disulphide oxidoreductase K00362,K22405 - 1.6.3.4,1.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004101 364.0
HFD3_k127_1091527_1 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000003319 217.0
HFD3_k127_1092341_0 PFAM ABC transporter transmembrane region K06147 - - 4.726e-228 721.0
HFD3_k127_1092341_1 ABC transporter, transmembrane region K06147,K18890 - - 2.305e-222 709.0
HFD3_k127_1092341_2 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004991 393.0
HFD3_k127_1092341_3 PFAM binding-protein-dependent transport systems inner membrane component K10234 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 313.0
HFD3_k127_1092341_4 ABC transporter substrate-binding protein K10232 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002375 280.0
HFD3_k127_1092341_5 COG1175 ABC-type sugar transport systems permease components K10233 - - 0.00000000000000000000000000000000000000000000000000000000000009828 224.0
HFD3_k127_1092341_6 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000004367 152.0
HFD3_k127_1092341_7 - - - - 0.00000000009382 71.0
HFD3_k127_1092341_9 Protein of unknown function (DUF2961) - - - 0.00000008961 65.0
HFD3_k127_1109600_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 524.0
HFD3_k127_1109600_1 SMART AAA ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 484.0
HFD3_k127_1109600_2 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 353.0
HFD3_k127_1109600_3 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000834 303.0
HFD3_k127_1109600_4 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004991 269.0
HFD3_k127_1109600_5 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000001035 213.0
HFD3_k127_1109600_6 PFAM Conserved TM helix repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000003254 186.0
HFD3_k127_1109600_7 - - - - 0.000000000000000000000000000000000000000000000008839 183.0
HFD3_k127_1109600_8 - - - - 0.00000000000000000000000000000000000007784 154.0
HFD3_k127_1110866_0 PFAM acyl-CoA dehydrogenase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004271 495.0
HFD3_k127_1110866_1 AMP-binding enzyme C-terminal domain K04110 - 6.2.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000453 361.0
HFD3_k127_1110866_2 PFAM Enoyl-CoA hydratase isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006598 327.0
HFD3_k127_1110866_3 PFAM short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001547 284.0
HFD3_k127_1110866_4 oxidation-reduction process - - - 0.000000000000000000000000000000000000000003743 158.0
HFD3_k127_1112118_0 elongation factor G K02355 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 463.0
HFD3_k127_1112118_1 TIGRFAM Translation elongation factor K02355 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000313 310.0
HFD3_k127_1112118_2 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000002825 239.0
HFD3_k127_1112118_3 Domain of unknown function DUF123 - - - 0.0000000000000000000003856 102.0
HFD3_k127_1112118_4 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000388 92.0
HFD3_k127_1122032_0 oxidation-reduction process - - - 0.0 1028.0
HFD3_k127_1122032_1 response regulator, receiver K02479 - - 0.00000000000000000000000000000000000000000000000000000000000000000000254 241.0
HFD3_k127_1122032_2 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000001176 248.0
HFD3_k127_1122032_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000001833 224.0
HFD3_k127_1122032_4 4-hydroxy-tetrahydrodipicolinate reductase K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.0000000000000000000000000000000000000000000000000002117 187.0
HFD3_k127_1122032_5 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000002263 186.0
HFD3_k127_1122032_6 Putative auto-transporter adhesin, head GIN domain - - - 0.0000000000000000000000000000001218 133.0
HFD3_k127_1122032_7 - - - - 0.00000000000000041 83.0
HFD3_k127_1143957_0 Oxidoreductase family, C-terminal alpha/beta domain K00010,K16044 - 1.1.1.18,1.1.1.369,1.1.1.371 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 486.0
HFD3_k127_1143957_1 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 302.0
HFD3_k127_1143957_2 NMT1/THI5 like K02051 - - 0.000000000000000000000000000000000000000000000004047 186.0
HFD3_k127_1143957_3 Cupin 2, conserved barrel domain protein K19547 - 5.3.3.19 0.00000000000000000000000000000000000000000000002886 173.0
HFD3_k127_1143957_4 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000001205 151.0
HFD3_k127_1143957_5 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000001867 98.0
HFD3_k127_115663_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 2.214e-222 709.0
HFD3_k127_115663_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K17223 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001208 269.0
HFD3_k127_115663_2 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K17223 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000002767 246.0
HFD3_k127_115663_3 Cytochrome c - - - 0.000000000000000000000000000001577 125.0
HFD3_k127_115663_4 Cytochrome c - - - 0.000000000000000000000000000008978 122.0
HFD3_k127_1158361_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 6.125e-218 693.0
HFD3_k127_1158361_1 ABC transporter transmembrane region K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009912 537.0
HFD3_k127_1158361_2 PFAM ABC transporter transmembrane region K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 516.0
HFD3_k127_1158361_3 COGs COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 338.0
HFD3_k127_1158361_4 PFAM LmbE family protein K18455 - 3.5.1.115 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 309.0
HFD3_k127_1158361_5 Isocitrate/isopropylmalate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000007209 250.0
HFD3_k127_1158361_6 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000001109 228.0
HFD3_k127_1158361_7 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000001537 119.0
HFD3_k127_1158361_8 Acetyltransferase (GNAT) family K00619 - 2.3.1.1 0.000000000000001362 82.0
HFD3_k127_1160161_0 ABC transporter transmembrane region K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 381.0
HFD3_k127_1160161_1 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001471 249.0
HFD3_k127_1160161_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000003564 173.0
HFD3_k127_1160161_3 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.0000000000000000000000000002802 119.0
HFD3_k127_1160161_4 Peptidase family M50 - - - 0.000000000000000000001403 96.0
HFD3_k127_1160161_5 Bacterial protein of unknown function (DUF922) - - - 0.0000000002491 71.0
HFD3_k127_1172892_0 radical SAM domain protein K06137,K06138 - 1.3.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000007476 258.0
HFD3_k127_1172892_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000281 242.0
HFD3_k127_1200659_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002203 297.0
HFD3_k127_1200659_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000009137 220.0
HFD3_k127_1200659_2 Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000000000000009676 224.0
HFD3_k127_1200659_3 retrograde transport, endosome to Golgi K07095 - - 0.0000000000000000000000000000000009994 132.0
HFD3_k127_1212112_0 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004865 486.0
HFD3_k127_1212112_1 Serine dehydrogenase proteinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 374.0
HFD3_k127_1212112_2 DinB family - - - 0.00000000000000000000000000000000000000000002354 168.0
HFD3_k127_1212112_3 Domain of unknown function (DUF1929) - - - 0.0000000000000000000001151 108.0
HFD3_k127_1212112_4 Ami_2 - - - 0.00000000005958 73.0
HFD3_k127_121718_0 Molybdopterin oxidoreductase K07812,K08352 - 1.7.2.3,1.8.5.5 6.161e-195 618.0
HFD3_k127_121718_1 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000000000000000008749 190.0
HFD3_k127_1217794_0 MmgE/PrpD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 492.0
HFD3_k127_1217794_1 enzyme of poly-gamma-glutamate biosynthesis (Capsule formation) K07282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 441.0
HFD3_k127_1217794_2 ABC transporter permease K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 380.0
HFD3_k127_1217794_3 UTRA K03710 - - 0.0000000000000000000000000000000000000000000000000006877 194.0
HFD3_k127_12198_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 1.032e-226 730.0
HFD3_k127_12198_1 cyclic 2,3-diphosphoglycerate synthetase activity - - - 2.046e-205 647.0
HFD3_k127_12198_10 PFAM DegV family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000003247 244.0
HFD3_k127_12198_11 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000003119 237.0
HFD3_k127_12198_12 geranylgeranyl reductase activity K14266 - 1.14.19.9 0.0000000000000000000000000000000000000000000000000000000000000000001102 246.0
HFD3_k127_12198_13 PFAM DegV family protein - - - 0.0000000000000000000000000000000000000000000000000000000000001484 222.0
HFD3_k127_12198_14 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0005488,GO:0005515,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046390,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.00000000000000000000000000000000000000000000001986 176.0
HFD3_k127_12198_15 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000000000000000000005149 151.0
HFD3_k127_12198_16 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000000282 147.0
HFD3_k127_12198_17 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - 0.0000000000000000000000000000704 122.0
HFD3_k127_12198_18 Asp23 family, cell envelope-related function - - - 0.0000000000000000000000000001318 121.0
HFD3_k127_12198_19 PFAM blue (type 1) copper domain protein K00368,K02638 - 1.7.2.1 0.0000000000000000000473 104.0
HFD3_k127_12198_2 PFAM Dak phosphatase K07030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 496.0
HFD3_k127_12198_20 Asp23 family, cell envelope-related function - - - 0.0000000000000000002913 93.0
HFD3_k127_12198_21 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000001297 81.0
HFD3_k127_12198_22 TPR repeat - - - 0.0000000000003579 77.0
HFD3_k127_12198_23 Ribosomal L28 family K02902 - - 0.0000000000004266 70.0
HFD3_k127_12198_3 oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005907 373.0
HFD3_k127_12198_4 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001178 280.0
HFD3_k127_12198_5 Acyl transferase domain K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002657 283.0
HFD3_k127_12198_6 3-oxoacyl- acyl-carrier-protein reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000863 276.0
HFD3_k127_12198_7 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001902 276.0
HFD3_k127_12198_8 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007626 256.0
HFD3_k127_12198_9 helix_turn_helix, Lux Regulon K11618 - - 0.000000000000000000000000000000000000000000000000000000000000000000002564 242.0
HFD3_k127_122807_0 Heavy-metal-associated domain K01534 - 3.6.3.3,3.6.3.5 2.066e-256 814.0
HFD3_k127_122807_1 Polysaccharide biosynthesis protein K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004004 597.0
HFD3_k127_122807_2 Heavy-metal-associated domain K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 567.0
HFD3_k127_122807_3 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 404.0
HFD3_k127_122807_4 PFAM conserved K07027 - - 0.000000000000000000000000000000000000000000000000000000000000266 224.0
HFD3_k127_122807_5 PFAM Bacterial regulatory protein, arsR family K21903 - - 0.000000000000000000000000000003286 124.0
HFD3_k127_122807_6 PFAM zinc finger, SWIM domain protein - - - 0.00000000000000005709 85.0
HFD3_k127_122807_7 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000003384 67.0
HFD3_k127_122807_8 Belongs to the ompA family K03640 - - 0.00000007762 66.0
HFD3_k127_1240025_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 505.0
HFD3_k127_1240025_1 Peptidase family M20/M25/M40 K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 471.0
HFD3_k127_1240025_2 Catalyzes the NADPH-dependent reduction of LysW - aminoadipate 6-phosphate to yield LysW -aminoadipate 6- semialdehyde K05829 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000534 455.0
HFD3_k127_1240025_3 PFAM NHL repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 299.0
HFD3_k127_1240025_4 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000000000000000000848 179.0
HFD3_k127_1240025_5 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000006013 149.0
HFD3_k127_1244668_0 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 2.008e-307 960.0
HFD3_k127_1251081_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008402 587.0
HFD3_k127_1251081_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 505.0
HFD3_k127_1251081_10 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000007852 155.0
HFD3_k127_1251081_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 323.0
HFD3_k127_1251081_3 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 294.0
HFD3_k127_1251081_4 Methionine synthase B12-binding module cap domain protein K00548,K15023 - 2.1.1.13,2.1.1.258 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004731 285.0
HFD3_k127_1251081_5 Queuosine biosynthesis protein K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006154 278.0
HFD3_k127_1251081_6 Belongs to the 'phage' integrase family K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003612 263.0
HFD3_k127_1251081_7 CoA-transferase family III K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000006321 227.0
HFD3_k127_1251081_8 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000007316 176.0
HFD3_k127_1251081_9 NUDIX domain K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000007626 164.0
HFD3_k127_1268226_0 TIGRFAM carbamoyl-phosphate synthase, small subunit K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 331.0
HFD3_k127_1286667_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 554.0
HFD3_k127_1286667_1 Glutathione peroxidase K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000000000000001461 220.0
HFD3_k127_1286667_2 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.00000004381 65.0
HFD3_k127_1286667_3 Polysulphide reductase, NrfD K04015 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000893 47.0
HFD3_k127_1315202_0 MFS_1 like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000134 245.0
HFD3_k127_1315202_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.0000000000000000000000000000006781 126.0
HFD3_k127_1315202_2 LUD domain K00782 - - 0.00000000000000000000003275 106.0
HFD3_k127_133488_0 PFAM cell divisionFtsK SpoIIIE K03466 GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000006984 243.0
HFD3_k127_133488_1 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000549 230.0
HFD3_k127_133488_2 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000000000002067 211.0
HFD3_k127_133488_3 YGGT family K02221 - - 0.000000000000000428 80.0
HFD3_k127_1346425_0 FGGY family of carbohydrate kinases, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003576 576.0
HFD3_k127_1346425_1 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 316.0
HFD3_k127_1346425_2 M42 glutamyl aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001031 295.0
HFD3_k127_1346425_3 ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001827 294.0
HFD3_k127_1346425_4 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002813 282.0
HFD3_k127_1346425_5 Oxidoreductase - - - 0.0000000000000005467 83.0
HFD3_k127_1346425_6 Transcriptional regulator - - - 0.000001963 51.0
HFD3_k127_135529_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000265 225.0
HFD3_k127_135529_1 - - - - 0.000000000000000000000005449 105.0
HFD3_k127_1365872_0 ATPase associated with various cellular K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000071 468.0
HFD3_k127_1365872_1 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001589 240.0
HFD3_k127_1375738_0 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009496 387.0
HFD3_k127_1375738_1 rRNA processing K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000003298 192.0
HFD3_k127_1375738_2 Integral membrane protein DUF92 - - - 0.000000000000000000000000000000000000000006924 159.0
HFD3_k127_1375738_3 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.00000000003453 64.0
HFD3_k127_13816_0 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 547.0
HFD3_k127_13816_1 protoporphyrinogen oxidase activity K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006612 452.0
HFD3_k127_13816_2 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 441.0
HFD3_k127_13816_3 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003032 307.0
HFD3_k127_13816_4 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000001741 284.0
HFD3_k127_13816_5 PFAM Chlorite dismutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001901 250.0
HFD3_k127_13816_6 PFAM regulatory protein, MerR - - - 0.0000000000000000000000000000003068 131.0
HFD3_k127_139319_0 protein involved in propionate catabolism - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003057 501.0
HFD3_k127_139319_1 PFAM CoA-transferase family III K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 328.0
HFD3_k127_139319_2 cyclase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007792 303.0
HFD3_k127_139319_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001432 293.0
HFD3_k127_139319_4 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001362 249.0
HFD3_k127_139319_5 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000001892 243.0
HFD3_k127_139319_6 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000009032 90.0
HFD3_k127_1402851_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008286 411.0
HFD3_k127_1402851_1 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 300.0
HFD3_k127_1402851_3 ATPases associated with a variety of cellular activities K10112,K10195 - - 0.0000000000000006062 78.0
HFD3_k127_1404510_0 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 601.0
HFD3_k127_1404510_1 PFAM ABC transporter related K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 471.0
HFD3_k127_1404510_10 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000002252 133.0
HFD3_k127_1404510_11 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.000000000000000000000000000002366 128.0
HFD3_k127_1404510_13 - K14337 - - 0.0000000000000000000000000003138 130.0
HFD3_k127_1404510_14 - - - - 0.00000000000000000000000006342 118.0
HFD3_k127_1404510_15 Cold shock protein K03704 - - 0.000000000000000000000001663 106.0
HFD3_k127_1404510_16 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000005943 91.0
HFD3_k127_1404510_17 Uncharacterized metal-binding protein (DUF2227) - - - 0.000000000000008877 81.0
HFD3_k127_1404510_18 - - - - 0.000000003551 61.0
HFD3_k127_1404510_2 nucleotide catabolic process K11751 - 3.1.3.5,3.6.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 324.0
HFD3_k127_1404510_3 PFAM peptidase M1, membrane alanine aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005931 318.0
HFD3_k127_1404510_4 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000001696 251.0
HFD3_k127_1404510_5 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000002723 249.0
HFD3_k127_1404510_6 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.0000000000000000000000000000000000000000000000000000000001074 212.0
HFD3_k127_1404510_7 Hydrolase of X-linked nucleoside diphosphate N terminal - - - 0.0000000000000000000000000000000000000000000001378 176.0
HFD3_k127_1404510_8 Alpha beta K06889 - - 0.0000000000000000000000000000000000000000000345 172.0
HFD3_k127_1404510_9 Thiopurine S-methyltransferase (TPMT) - - - 0.000000000000000000000000000000000008933 146.0
HFD3_k127_142455_0 COG1175 ABC-type sugar transport systems permease components K02025 - - 0.00000000000000000000000000000000000000000000000000000000000005151 225.0
HFD3_k127_142455_1 carbohydrate transport K02027 - - 0.000000000000000000000000000000000000000000000000000004426 207.0
HFD3_k127_142455_2 binding-protein-dependent transport systems inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000004152 179.0
HFD3_k127_142455_3 FCD - - - 0.000000000000000000000000000000000000000000796 165.0
HFD3_k127_142455_4 conserved protein, contains double-stranded beta-helix domain - - - 0.00000000000007882 76.0
HFD3_k127_142455_5 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000004905 70.0
HFD3_k127_1431499_0 Transposase IS116/IS110/IS902 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 483.0
HFD3_k127_1431499_1 xanthine dehydrogenase activity K03519 - 1.2.5.3 0.0000000000000000000000000000000000001737 147.0
HFD3_k127_1431499_2 Belongs to the SOS response-associated peptidase family - - - 0.0000000000003057 72.0
HFD3_k127_1436471_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 0.0000000000000000000000000000000000001853 143.0
HFD3_k127_1436471_1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K02823 - - 0.00000000000000000000000000000002749 135.0
HFD3_k127_1436471_2 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14 0.00000000000000000001451 101.0
HFD3_k127_1436471_3 Virulence factor BrkB K07058 - - 0.000000000000000001842 96.0
HFD3_k127_1436471_4 Methionine biosynthesis protein MetW - - - 0.00000000000000709 84.0
HFD3_k127_145068_0 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000004057 251.0
HFD3_k127_145068_1 metallopeptidase activity K06402 - - 0.000000000000000000000000000000000000003739 154.0
HFD3_k127_145068_2 sh3 domain protein K12132,K15539 - 2.7.11.1 0.000003966 57.0
HFD3_k127_1475332_0 PFAM Uncharacterised protein family UPF0182 K09118 - - 1.814e-218 701.0
HFD3_k127_1475332_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 415.0
HFD3_k127_1475332_2 - K07112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000001787 169.0
HFD3_k127_1475332_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.000000000000000006256 87.0
HFD3_k127_1475332_4 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000003966 86.0
HFD3_k127_1475332_5 phosphatidate phosphatase activity K19302 - 3.6.1.27 0.000000009937 65.0
HFD3_k127_1475332_6 - - - - 0.00006142 47.0
HFD3_k127_152402_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003378 490.0
HFD3_k127_152402_1 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002883 285.0
HFD3_k127_152402_2 - K14340 - - 0.00000000000000000000000000000000000000000000000000000000000000006905 243.0
HFD3_k127_152402_3 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000001058 87.0
HFD3_k127_1525701_0 Glycoside hydrolase family 44 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008765 546.0
HFD3_k127_1525701_1 Isocitrate/isopropylmalate dehydrogenase K00052,K10978 GO:0006082,GO:0006575,GO:0006732,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016053,GO:0019297,GO:0019298,GO:0019752,GO:0032787,GO:0042398,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 1.1.1.85,1.1.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005825 501.0
HFD3_k127_1525701_2 CAAX protease self-immunity - - - 0.0000000000000000000000000000000000000000000000000000000000000009072 227.0
HFD3_k127_1525701_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000002452 221.0
HFD3_k127_1525701_4 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000006986 226.0
HFD3_k127_1525701_5 - - - - 0.00000000000000000000000003346 119.0
HFD3_k127_1525701_6 Dodecin K09165 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000001924 106.0
HFD3_k127_1525701_7 NUDIX domain - - - 0.0000000000000002095 86.0
HFD3_k127_1525701_8 Dual-specificity protein phosphatase K14819 - 3.1.3.16,3.1.3.48 0.0004929 49.0
HFD3_k127_1532223_0 PFAM UBA THIF-type NAD FAD binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 353.0
HFD3_k127_1554201_0 Belongs to the aldehyde dehydrogenase family K00128,K00130,K00135,K00138,K00146 - 1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.39,1.2.1.79,1.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 550.0
HFD3_k127_1554201_1 KR domain K00038 - 1.1.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009406 423.0
HFD3_k127_1554201_2 AAA domain (dynein-related subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 394.0
HFD3_k127_1554201_3 SMART von Willebrand factor, type A K07161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008303 365.0
HFD3_k127_1554201_4 GMP synthase (glutamine-hydrolyzing) activity K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005813 274.0
HFD3_k127_1554201_5 YHS domain K07402 - - 0.000000000000000000000000000000000000000000000000000000000003097 218.0
HFD3_k127_1554201_6 Choline/ethanolamine kinase - - - 0.0000000000000000000352 98.0
HFD3_k127_1554201_7 Carbon monoxide dehydrogenase subunit G (CoxG) K09386 - - 0.0000000004128 67.0
HFD3_k127_1554554_0 carboxylic ester hydrolase activity K03928 - 3.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 331.0
HFD3_k127_1554554_1 Domain of unknown function (DUF4203) - - - 0.00000000000000000006564 96.0
HFD3_k127_1554554_2 response regulator - - - 0.000000004826 59.0
HFD3_k127_1561480_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 407.0
HFD3_k127_1561480_1 Sugar kinase of the NBD HSP70 family, may containing an N-terminal HTH domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 361.0
HFD3_k127_1561480_2 domain, Protein K09766 - - 0.000000000000000000000000000003777 130.0
HFD3_k127_1561480_3 methylated DNA-protein cysteine methyltransferase K07443 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363 - 0.0000000000000000000000001057 112.0
HFD3_k127_156157_0 oligosaccharyl transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005188 621.0
HFD3_k127_156157_1 FAD dependent oxidoreductase K00313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007189 434.0
HFD3_k127_156157_2 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 370.0
HFD3_k127_156157_3 Protein of unknown function (DUF2723) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 343.0
HFD3_k127_156157_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000004104 213.0
HFD3_k127_156157_5 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000000000000000000000000006046 161.0
HFD3_k127_156157_6 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S K03855 - - 0.00000000000000000000000001365 111.0
HFD3_k127_156157_7 Protein of unknown function (DUF2723) - - - 0.00000000000000000004885 106.0
HFD3_k127_156157_8 Psort location CytoplasmicMembrane, score - - - 0.000000000005943 79.0
HFD3_k127_1561693_0 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007525 469.0
HFD3_k127_1561693_1 PFAM UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006459 396.0
HFD3_k127_1561693_2 Pyridoxal-phosphate dependent enzyme K12339 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000003991 264.0
HFD3_k127_1561693_3 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000007486 263.0
HFD3_k127_1561693_4 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000008151 189.0
HFD3_k127_1561693_5 Sulfurtransferase TusA K00392,K04085 - 1.8.7.1 0.0000000000000000000009599 100.0
HFD3_k127_1562953_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 306.0
HFD3_k127_1562953_1 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000003204 251.0
HFD3_k127_1562953_2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000008804 246.0
HFD3_k127_1562953_3 WD40-like Beta Propeller Repeat K03641 - - 0.000000000000000000000000517 118.0
HFD3_k127_1562953_4 Involved in the TonB-independent uptake of proteins K03641 - - 0.00000000000000000005544 102.0
HFD3_k127_1562953_5 PFAM Haloacid dehalogenase domain protein hydrolase K07025 - - 0.000000009261 61.0
HFD3_k127_1563784_0 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006328 299.0
HFD3_k127_1563784_1 periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000002409 197.0
HFD3_k127_1563784_2 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.000000000000005922 77.0
HFD3_k127_156439_0 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 427.0
HFD3_k127_156439_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K00320 - 1.5.98.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000465 417.0
HFD3_k127_156439_2 haloacid dehalogenase K01560 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000000000003604 221.0
HFD3_k127_156439_3 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000003533 134.0
HFD3_k127_156439_4 SET domain K07117 - - 0.00000000000000000000000000009984 123.0
HFD3_k127_156461_0 PFAM PrkA AAA domain K07180 - - 6.715e-247 780.0
HFD3_k127_156461_1 Stage V sporulation protein R K06415 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008709 349.0
HFD3_k127_156461_2 Protein of unknown function (DUF444) K09786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003092 336.0
HFD3_k127_156461_3 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000001052 162.0
HFD3_k127_156461_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000001002 145.0
HFD3_k127_156461_5 belongs to the sigma-70 factor family, ECF subfamily - - - 0.00000000000000000000000000000001876 134.0
HFD3_k127_156461_6 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000001536 124.0
HFD3_k127_156461_9 synthetase K12240 - - 0.0001104 48.0
HFD3_k127_1579734_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000571 400.0
HFD3_k127_1579734_1 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008954 302.0
HFD3_k127_1579734_2 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000883 205.0
HFD3_k127_1582923_0 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 1.465e-224 717.0
HFD3_k127_1582923_1 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 1.98e-208 674.0
HFD3_k127_1582923_2 PFAM glycosyl transferase group 1 K15521 - 2.4.1.250 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 435.0
HFD3_k127_1582923_3 gluconolactonase activity K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000002234 177.0
HFD3_k127_1582923_4 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000002609 136.0
HFD3_k127_1582923_7 Colicin V production protein K03558 - - 0.0001038 51.0
HFD3_k127_158592_0 Peptide nickel ABC transporter, substrate-binding protein K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005024 259.0
HFD3_k127_158592_1 regulation of single-species biofilm formation K02342,K03763,K13573 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000001952 204.0
HFD3_k127_158592_2 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.000000000000000000000000002976 116.0
HFD3_k127_158592_3 Acetyltransferase (GNAT) family - - - 0.0000000000002091 82.0
HFD3_k127_158592_4 Putative adhesin - - - 0.0000002698 61.0
HFD3_k127_1589494_0 Zn-dependent dipeptidase, microsomal dipeptidase K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009924 565.0
HFD3_k127_1589494_1 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009538 451.0
HFD3_k127_1589494_2 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000000000000155 219.0
HFD3_k127_1589494_3 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000002308 205.0
HFD3_k127_1589494_4 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily - - - 0.00000000000000000000000000000000000000000000000000009608 191.0
HFD3_k127_1589494_5 Flavodoxin domain K00230 - 1.3.5.3 0.000000000000000000000000000000000002496 145.0
HFD3_k127_1591163_0 MacB-like periplasmic core domain K02004 - - 9.52e-230 736.0
HFD3_k127_1591163_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000134 199.0
HFD3_k127_15953_0 PFAM UDP-glucose GDP-mannose dehydrogenase K02472,K02474,K13015 - 1.1.1.136,1.1.1.336 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 485.0
HFD3_k127_15953_1 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 319.0
HFD3_k127_15953_2 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005976 250.0
HFD3_k127_15953_3 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000001026 207.0
HFD3_k127_1596090_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 508.0
HFD3_k127_1596090_1 DNA recombination-mediator protein A K03168,K04096 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009309 398.0
HFD3_k127_1596090_10 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000000429 144.0
HFD3_k127_1596090_11 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000001447 103.0
HFD3_k127_1596090_12 Belongs to the UPF0109 family K06960 - - 0.0000000000000000000123 94.0
HFD3_k127_1596090_13 Redoxin - - - 0.00000000003664 64.0
HFD3_k127_1596090_2 Mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 374.0
HFD3_k127_1596090_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 387.0
HFD3_k127_1596090_4 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001505 255.0
HFD3_k127_1596090_5 Winged helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001193 243.0
HFD3_k127_1596090_6 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000372 237.0
HFD3_k127_1596090_7 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000001481 248.0
HFD3_k127_1596090_8 Appr-1'-p processing enzyme - - - 0.00000000000000000000000000000000000000000000000000000000001371 211.0
HFD3_k127_1596090_9 TIGRFAM sugar-phosphate isomerases, RpiB LacA LacB family K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000004884 180.0
HFD3_k127_159781_0 Cytochrome c554 and c-prime K03620 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006022 264.0
HFD3_k127_159781_1 response regulator K22010 - - 0.00000000000000000000000000000000000000000000000000000000001878 211.0
HFD3_k127_159781_2 Histidine kinase - - - 0.000000000000000000000000000000000000000002149 167.0
HFD3_k127_159781_3 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.000000000000000000000000000000000000007911 149.0
HFD3_k127_159781_4 Cytochrome b(N-terminal)/b6/petB K03887 - - 0.00000000000000000000000000000001541 128.0
HFD3_k127_159781_5 - - - - 0.000000000000000000007749 103.0
HFD3_k127_159781_6 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 0.00000000000000006381 86.0
HFD3_k127_159781_7 4-vinyl reductase, 4VR K06382,K07013 - 3.1.3.16 0.000000004642 64.0
HFD3_k127_159781_8 anaerobic respiration K02568 - - 0.00000009306 65.0
HFD3_k127_1598668_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 389.0
HFD3_k127_1598668_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004619 308.0
HFD3_k127_160355_0 calcium- and calmodulin-responsive adenylate cyclase activity K07260 - 3.4.17.14 0.000000000000000000000000000000000000000000000000000000000000000000000001277 257.0
HFD3_k127_160355_1 TIGRFAM amidase, hydantoinase carbamoylase K06016 - 3.5.1.6,3.5.1.87 0.000000000000000000000000000000000009501 142.0
HFD3_k127_160355_2 COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K12528 - - 0.000000000000000000000000362 105.0
HFD3_k127_1611280_0 Histidine kinase K02480 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 323.0
HFD3_k127_1611280_1 Two component transcriptional regulator, LuxR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004556 289.0
HFD3_k127_1611280_2 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000003743 229.0
HFD3_k127_1611280_3 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000000000000000005969 166.0
HFD3_k127_1611280_4 response regulator K07689 - - 0.0000000000000000000000006451 109.0
HFD3_k127_1611280_5 Lysin motif - - - 0.0000000000000000005382 98.0
HFD3_k127_1614454_0 Belongs to the NAGSA dehydrogenase family. Type 1 subfamily K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005144 273.0
HFD3_k127_1614454_1 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000003077 265.0
HFD3_k127_1614454_2 acetylornithine aminotransferase K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000184 258.0
HFD3_k127_161514_0 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 580.0
HFD3_k127_161514_1 PFAM peptidase S1 and S6, chymotrypsin Hap K08070 - 1.3.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005795 318.0
HFD3_k127_161514_10 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000002594 133.0
HFD3_k127_161514_11 rhodanese-related sulfurtransferase - - - 0.0000000000000000000000000009599 117.0
HFD3_k127_161514_12 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000007794 104.0
HFD3_k127_161514_13 - - - - 0.000000000000000003827 94.0
HFD3_k127_161514_14 alkyl hydroperoxide reductase activity - - - 0.0000000000000004671 80.0
HFD3_k127_161514_15 transcriptional K21600 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000001202 77.0
HFD3_k127_161514_16 - - - - 0.00000000001988 70.0
HFD3_k127_161514_17 Regulatory protein, FmdB family - - - 0.0000000001891 63.0
HFD3_k127_161514_18 NUBPL iron-transfer P-loop NTPase - - - 0.00002618 48.0
HFD3_k127_161514_2 Archaeal transcriptional regulator TrmB - - - 0.000000000000000000000000000000000000000000000000000000000000000003971 238.0
HFD3_k127_161514_3 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000002196 224.0
HFD3_k127_161514_4 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000005019 202.0
HFD3_k127_161514_5 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000001403 191.0
HFD3_k127_161514_6 PFAM OsmC family protein K07397 - - 0.00000000000000000000000000000000000000005486 156.0
HFD3_k127_161514_7 CoA binding domain K06929 - - 0.000000000000000000000000000000000000001808 150.0
HFD3_k127_161514_8 Thioredoxin domain - - - 0.00000000000000000000000000000000000001532 149.0
HFD3_k127_161514_9 Thioredoxin-like domain K03671 - - 0.000000000000000000000000000000000004848 139.0
HFD3_k127_161699_0 carboxylic ester hydrolase activity K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003466 287.0
HFD3_k127_161699_1 WYL domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001069 279.0
HFD3_k127_161699_2 Bacterial transcription activator, effector binding domain - - - 0.00000000000000000000000000000000000000000000000168 177.0
HFD3_k127_161699_3 PFAM Bile acid sodium symporter K03325 - - 0.00000000000000000000000001092 111.0
HFD3_k127_161699_4 Tetratricopeptide repeat - - - 0.00004449 52.0
HFD3_k127_1617668_0 Amino acid polyamine organocation transporter, APC superfamily K03294 - - 2.926e-209 663.0
HFD3_k127_1617668_1 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 502.0
HFD3_k127_1617668_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031004,GO:0031224,GO:0031226,GO:0031420,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007431 480.0
HFD3_k127_1617668_3 AMP binding - - - 0.00000000000000000000000000000000000001523 151.0
HFD3_k127_1620234_0 Glycosyl transferase family group 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 394.0
HFD3_k127_1620234_1 TIGRFAM small GTP-binding protein K06945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005875 256.0
HFD3_k127_1620234_2 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007351 254.0
HFD3_k127_1620234_3 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000001369 192.0
HFD3_k127_1620234_4 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000000000000000004783 184.0
HFD3_k127_1620234_5 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000001631 115.0
HFD3_k127_1620234_6 4-vinyl reductase, 4VR K06382,K07013 - 3.1.3.16 0.000000007194 65.0
HFD3_k127_1629783_0 Glycoside hydrolase, family 20 - - - 3.717e-223 709.0
HFD3_k127_1629783_1 Phosphoribosylglycinamide synthetase, C domain K11788 GO:0003674,GO:0003824,GO:0004637,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009112,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:1901360,GO:1901564 6.3.3.1,6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 620.0
HFD3_k127_1629783_2 IMP dehydrogenase / GMP reductase domain K00088 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 591.0
HFD3_k127_1629783_3 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007333 348.0
HFD3_k127_1629783_4 Uncharacterised ACR (DUF711) K09157 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001844 280.0
HFD3_k127_1629783_5 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000001926 218.0
HFD3_k127_1629783_6 PFAM carbohydrate kinase K00854 - 2.7.1.17 0.0000000000000001078 80.0
HFD3_k127_1629783_7 Septum formation initiator K13052 - - 0.00005329 50.0
HFD3_k127_1638646_0 Amidohydrolase family K01466 - 3.5.2.5 7.438e-223 699.0
HFD3_k127_1638646_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005936 319.0
HFD3_k127_1638646_2 PFAM ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 289.0
HFD3_k127_1638646_3 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003882 266.0
HFD3_k127_1638646_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000241 100.0
HFD3_k127_1640987_0 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 435.0
HFD3_k127_1640987_1 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.00000000000000000000000000000000000000000000000000000001433 202.0
HFD3_k127_1640987_2 PFAM Rieske 2Fe-2S K02636 - 1.10.9.1 0.00000000000000000000001561 106.0
HFD3_k127_1641329_0 Glycosyltransferase 28 domain K03715 - 2.4.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003301 290.0
HFD3_k127_1641329_1 Lytic transglycosylase catalytic K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004069 289.0
HFD3_k127_1641329_2 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester - - - 0.000000000000000000000000000000000000000000000000000000002274 204.0
HFD3_k127_1641329_3 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000001809 206.0
HFD3_k127_1641329_4 Inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000003305 184.0
HFD3_k127_1641329_5 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.00000000000000000000000000000000000000004179 156.0
HFD3_k127_1641329_6 COGs COG1653 ABC-type sugar transport system periplasmic component K02027 - - 0.000000000000000000000001979 117.0
HFD3_k127_1641329_7 Bacterial protein of unknown function (DUF951) - - - 0.000000000000000000000004265 102.0
HFD3_k127_164276_0 ABC transporter substrate-binding protein K02027,K05813 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 374.0
HFD3_k127_164276_1 Secreted repeat of unknown function - - - 0.0000000000000000000000007452 111.0
HFD3_k127_1653088_0 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000007599 221.0
HFD3_k127_1653088_1 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000000000002267 174.0
HFD3_k127_1653088_2 C-terminal four TMM region of protein-O-mannosyltransferase - - - 0.00000000000000000000000000000000001456 147.0
HFD3_k127_1662029_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 1.387e-277 865.0
HFD3_k127_1662029_1 PLD-like domain K17717 - 3.1.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002989 278.0
HFD3_k127_1662029_2 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000001732 224.0
HFD3_k127_1662029_3 4Fe-4S dicluster domain K00196 - - 0.00000000000000000000000000000000000000000000000000364 187.0
HFD3_k127_1662029_4 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.000000000000000000000000000000004289 143.0
HFD3_k127_1662029_5 PFAM Phosphoglycerate mutase K02226,K22305 - 3.1.3.3,3.1.3.73 0.00000000000000002105 89.0
HFD3_k127_1662029_6 PFAM peptidase M24 - - - 0.0005693 43.0
HFD3_k127_1663005_0 2-oxoisovalerate dehydrogenase K00167,K21417 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007404 434.0
HFD3_k127_1663005_1 e3 binding domain K00658,K09699 - 2.3.1.168,2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 439.0
HFD3_k127_1663005_2 Dehydrogenase E1 component K00166 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006309 385.0
HFD3_k127_1663005_3 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000004108 263.0
HFD3_k127_1663005_4 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000006466 235.0
HFD3_k127_1663005_5 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000004939 170.0
HFD3_k127_1663005_6 Thiopurine S-methyltransferase (TPMT) K00569 - 2.1.1.67 0.000000000000000000000000000000000000000000002419 172.0
HFD3_k127_1663005_7 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000000000000000003428 168.0
HFD3_k127_1663005_8 PFAM fumarate lyase K01679 - 4.2.1.2 0.000000000000000000000000000000000008379 137.0
HFD3_k127_1670936_0 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006466 432.0
HFD3_k127_1670936_1 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 349.0
HFD3_k127_1670936_2 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 310.0
HFD3_k127_1670936_3 Peptidase family M28 K19701 - 3.4.11.10,3.4.11.6 0.000000000000000000000000000000000000000000000000000000000000003285 233.0
HFD3_k127_1670936_4 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000007594 219.0
HFD3_k127_1670936_5 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000003314 171.0
HFD3_k127_1670936_6 O-antigen polymerase K18814 - - 0.00002656 54.0
HFD3_k127_1681881_0 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002951 464.0
HFD3_k127_1681881_1 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000002318 169.0
HFD3_k127_1689219_0 oligosaccharyl transferase activity K07151 - 2.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004184 432.0
HFD3_k127_1689219_1 oligosaccharyl transferase activity K07151 - 2.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000008124 250.0
HFD3_k127_1689219_2 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 0.0000000000000000000000000000000001039 143.0
HFD3_k127_1689219_3 C-terminal four TMM region of protein-O-mannosyltransferase K00728 - 2.4.1.109 0.0000000000008865 81.0
HFD3_k127_1689219_4 LysM domain - - - 0.00000000001157 74.0
HFD3_k127_1689219_5 Psort location CytoplasmicMembrane, score K00368 - 1.7.2.1 0.0000002624 57.0
HFD3_k127_1689378_0 Multicopper oxidase K00368 - 1.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008196 419.0
HFD3_k127_1689378_1 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 308.0
HFD3_k127_1689378_2 transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 299.0
HFD3_k127_1689378_3 Iron dependent repressor, metal binding and dimerisation domain K03709 - - 0.00000000000000000000000000000000000000000000000000000000000075 217.0
HFD3_k127_1689378_4 Uncharacterized protein conserved in bacteria (DUF2255) - - - 0.0000000000000000000000000000000006291 132.0
HFD3_k127_1689378_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000002018 134.0
HFD3_k127_1696221_0 Alpha amylase, C-terminal all-beta domain K00700 - 2.4.1.18 0.00000000000000000000002236 100.0
HFD3_k127_1696221_1 Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000002423 60.0
HFD3_k127_1696221_2 methyltransferase activity - - - 0.0003798 44.0
HFD3_k127_1697886_0 PFAM ABC transporter related K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 339.0
HFD3_k127_1697886_1 ABC-type polar amino acid transport system ATPase component K09972 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 330.0
HFD3_k127_1697886_2 Binding-protein-dependent transport system inner membrane component K02029 - - 0.0000000000000000000000000000000000000000000000000000000000009075 220.0
HFD3_k127_1697886_3 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000002287 208.0
HFD3_k127_1697886_4 COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain K02030 - - 0.0000000000000000000000000000000000000000000000000000000002495 210.0
HFD3_k127_1700863_0 FAD dependent oxidoreductase K00244 - 1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 449.0
HFD3_k127_1700863_1 FAD dependent oxidoreductase K00244 - 1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009612 384.0
HFD3_k127_1700863_2 Receptor family ligand binding region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007006 250.0
HFD3_k127_170469_0 PFAM isocitrate lyase and phosphorylmutase K01637 - 4.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 619.0
HFD3_k127_170469_1 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 - 2.5.1.47 0.000000000009222 65.0
HFD3_k127_170469_2 gluconolactonase activity K13280 - 3.4.21.89 0.00000002514 65.0
HFD3_k127_1724780_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005638 353.0
HFD3_k127_1724780_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005766 278.0
HFD3_k127_172902_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 563.0
HFD3_k127_172902_1 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 474.0
HFD3_k127_172902_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000001346 268.0
HFD3_k127_172902_3 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000003022 256.0
HFD3_k127_172902_4 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000009917 231.0
HFD3_k127_172902_5 Belongs to the TrpC family K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000007589 223.0
HFD3_k127_172902_6 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000000000001871 204.0
HFD3_k127_172902_7 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis K06208 - 5.4.99.5 0.0000000000000000000000000000000002059 135.0
HFD3_k127_172902_8 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0005488,GO:0036094,GO:0048037,GO:0050661,GO:0050662,GO:0097159,GO:1901265,GO:1901363 1.1.1.25 0.0000000000000000000000000004236 115.0
HFD3_k127_172902_9 Transposase, IS116 IS110 IS902 family - - - 0.0000005604 58.0
HFD3_k127_1731308_0 protein related to plant photosystem II stability assembly factor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 504.0
HFD3_k127_1731308_1 DNA-3-methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000194 270.0
HFD3_k127_1731308_2 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002339 269.0
HFD3_k127_1731308_3 TIGRFAM Acetoacetyl-CoA synthase K01907 - 6.2.1.16 0.000000000000000000000000000000000000000000000000000000000001289 211.0
HFD3_k127_1731308_4 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000004725 179.0
HFD3_k127_1731308_5 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000002803 166.0
HFD3_k127_1731308_6 Winged helix DNA-binding domain K09927 - - 0.0000000000000000001776 91.0
HFD3_k127_1731308_7 Mo-molybdopterin cofactor metabolic process K03636 - - 0.000000000000000005648 94.0
HFD3_k127_1746843_0 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 297.0
HFD3_k127_1746843_1 Domain of unknown function (DUF4129) - - - 0.00000000000000000000000000000000000004219 161.0
HFD3_k127_1746843_2 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.0000000000000000000000000000000000002675 149.0
HFD3_k127_1746843_3 transferase activity, transferring acyl groups - - - 0.00000000000000000000000004191 115.0
HFD3_k127_1746843_4 PBS lyase HEAT-like repeat - - - 0.0007869 50.0
HFD3_k127_1760683_0 helix_turn_helix, Lux Regulon K11618 - - 0.000000000000000000000000000000000000000000000000000000000000000004217 238.0
HFD3_k127_1760683_1 Glyoxalase-like domain K08234 - - 0.000000000000000000000000000000000000000000000000000004011 192.0
HFD3_k127_1760683_2 Protein of unknown function with HXXEE motif - - - 0.000000000000000000000000000000000000000007444 160.0
HFD3_k127_1760683_3 Histidine kinase - - - 0.00000000000000000000000000000002873 140.0
HFD3_k127_1760683_4 Domain of unknown function (DUF4131) K02238 - - 0.0000000000000000000000000000006549 130.0
HFD3_k127_1760683_5 histidine kinase, dimerisation and phosphoacceptor region - - - 0.000000000002438 76.0
HFD3_k127_1760683_6 - - - - 0.00009176 48.0
HFD3_k127_1761376_0 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007881 405.0
HFD3_k127_1761376_1 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002634 327.0
HFD3_k127_1761376_2 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.00000000000000000000000000000000004141 153.0
HFD3_k127_1761376_3 - - - - 0.000000000003567 79.0
HFD3_k127_1762918_0 DNA polymerase III delta subunit K02340 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.00000000000000000000000000000000000000000001114 174.0
HFD3_k127_1762918_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000005436 144.0
HFD3_k127_1762918_2 PFAM cell divisionFtsK SpoIIIE K03466 GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00004721 48.0
HFD3_k127_1786517_0 Pfam:DUF162 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 600.0
HFD3_k127_1786517_1 PFAM FAD linked oxidase domain protein K00102 - 1.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 586.0
HFD3_k127_1786517_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000842 475.0
HFD3_k127_1786517_3 Cysteine-rich domain - - - 0.0000000000000000000000000000000000000001848 151.0
HFD3_k127_1799596_0 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 458.0
HFD3_k127_1799596_1 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 382.0
HFD3_k127_1799596_2 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003131 371.0
HFD3_k127_1799596_3 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 317.0
HFD3_k127_1799596_4 Glycosyl transferase 4-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 301.0
HFD3_k127_1799596_5 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000431 259.0
HFD3_k127_1799596_6 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000004956 222.0
HFD3_k127_1799596_7 - - - - 0.000000000005388 79.0
HFD3_k127_1799596_8 Protein of unknown function (DUF1616) - - - 0.000000005159 67.0
HFD3_k127_180147_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1025.0
HFD3_k127_180147_1 FCD - - - 0.00000000000009832 73.0
HFD3_k127_1823283_0 Transketolase, pyrimidine binding domain K00167,K21417 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005262 429.0
HFD3_k127_1823283_1 Dehydrogenase E1 component K00166 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 354.0
HFD3_k127_1823283_2 PFAM band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005194 345.0
HFD3_k127_1823283_3 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001193 244.0
HFD3_k127_1823283_4 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000127 167.0
HFD3_k127_1823283_5 - - - - 0.0000000000000000000000000002655 132.0
HFD3_k127_1823283_6 PFAM regulatory protein GntR HTH K07979 - - 0.00000000000000000000000001901 113.0
HFD3_k127_1823283_7 - - - - 0.000000000000000000000002762 119.0
HFD3_k127_1823283_9 - - - - 0.00000000001025 78.0
HFD3_k127_1833898_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 364.0
HFD3_k127_1833898_1 histidine kinase A domain protein K02484 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004676 282.0
HFD3_k127_1833898_2 Glutamine amidotransferase domain K22081 - 2.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000001673 258.0
HFD3_k127_1833898_3 PFAM formylmethanofuran dehydrogenase, subunit E region K11261 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000004893 244.0
HFD3_k127_1833898_4 amino acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000001426 252.0
HFD3_k127_1833898_5 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000004129 216.0
HFD3_k127_1833898_6 OsmC-like protein K09136 - - 0.0000000000000000000000000000000000000000000000002868 180.0
HFD3_k127_1833898_7 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000000008463 162.0
HFD3_k127_1833898_8 PFAM glutamate synthase alpha subunit domain protein K22082 - 2.1.1.21 0.0000000000000000000000000000000000001936 150.0
HFD3_k127_1841487_0 Immune inhibitor A peptidase M6 K09607 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 587.0
HFD3_k127_1841487_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007389 545.0
HFD3_k127_1841487_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883,K15526 GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 6.1.1.16,6.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009598 382.0
HFD3_k127_1841487_3 SMART Nucleotide binding protein, PINc - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004155 384.0
HFD3_k127_1848577_0 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 - 2.1.1.219,2.1.1.220 0.00000000000000000000000000000000000000000000000000000000000000000000003082 251.0
HFD3_k127_1848577_1 Cysteine-rich secretory protein family - - - 0.0000000000000000000000003169 116.0
HFD3_k127_1848577_2 PFAM GGDEF domain containing protein - - - 0.00000000000000000002473 104.0
HFD3_k127_1848577_4 Methyltransferase domain - - - 0.00000004448 58.0
HFD3_k127_1848577_5 STAS domain K04749 - - 0.000003158 55.0
HFD3_k127_1869241_0 Binding-protein-dependent transport system inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 537.0
HFD3_k127_1869241_1 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008122 272.0
HFD3_k127_1869241_2 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000634 146.0
HFD3_k127_1875615_0 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000001672 199.0
HFD3_k127_1875615_1 permease - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.000000000000000000000000000000000000000000000000003132 198.0
HFD3_k127_1875617_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 3.779e-230 728.0
HFD3_k127_1875617_1 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.00000000000000000000000001206 111.0
HFD3_k127_1875617_3 PFAM Transcription factor CarD K07736 - - 0.00007283 48.0
HFD3_k127_188267_0 PFAM multi antimicrobial extrusion protein MatE - - - 0.00000000000000000000000000000000000000000000000000000000009429 214.0
HFD3_k127_188267_1 esterase - - - 0.00000000000000000000000000000000005341 148.0
HFD3_k127_188267_2 Putative esterase - - - 0.0000000000000000000000000000001123 138.0
HFD3_k127_188267_3 OpgC protein - - - 0.0000000000000000001827 98.0
HFD3_k127_188267_4 depolymerase - - - 0.000000002438 69.0
HFD3_k127_1884064_0 PFAM Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 1.929e-200 640.0
HFD3_k127_1884064_1 transcriptional regulator K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.000000000000000001058 92.0
HFD3_k127_1884064_2 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000742 88.0
HFD3_k127_1897389_0 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 2.923e-237 745.0
HFD3_k127_1897389_1 Pyridoxal-dependent decarboxylase conserved domain K01634 - 4.1.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 518.0
HFD3_k127_1897389_2 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004563 286.0
HFD3_k127_1897389_3 membrane transporter protein K07090 - - 0.00000000000000000000000000000009479 131.0
HFD3_k127_1921842_0 DJ-1/PfpI family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002765 524.0
HFD3_k127_1921842_1 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000000000000000000000000000000000000001145 247.0
HFD3_k127_1921842_2 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000128 162.0
HFD3_k127_1934145_0 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 2.329e-244 766.0
HFD3_k127_1934145_1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.00000001766 57.0
HFD3_k127_1938042_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 473.0
HFD3_k127_1938042_1 SnoaL-like polyketide cyclase - - - 0.0000003822 57.0
HFD3_k127_1961077_0 Pyridoxal-phosphate dependent enzyme K01697,K01738 - 2.5.1.47,4.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 587.0
HFD3_k127_1961077_1 extracellular solute-binding protein, family 5 K02035,K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004954 293.0
HFD3_k127_1961077_2 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003245 285.0
HFD3_k127_1961077_3 - - - - 0.00000000000000000000000000000000000000000000000000000000003898 217.0
HFD3_k127_1976353_0 PFAM metal-dependent phosphohydrolase, HD sub domain K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004344 437.0
HFD3_k127_1976353_1 ATPase activity K03546,K16786,K16787,K19171 - - 0.0000000000000000000000000000000000001907 146.0
HFD3_k127_1982291_0 Belongs to the thiolase family K00626 - 2.3.1.9 3.774e-212 663.0
HFD3_k127_1982291_1 Enoyl-CoA hydratase isomerase K07539 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788 3.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 591.0
HFD3_k127_1982291_2 Enoyl-(Acyl carrier protein) reductase K00023,K00059 - 1.1.1.100,1.1.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004712 418.0
HFD3_k127_1982291_3 PaaX-like protein K02616 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003364 291.0
HFD3_k127_1982291_4 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000007444 175.0
HFD3_k127_1990863_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000003895 224.0
HFD3_k127_1990863_1 Domain of unknown function (DUF1330) - - - 0.0000000000000000000000000000004612 124.0
HFD3_k127_1990863_2 ester cyclase - - - 0.00000000000000000000000001222 113.0
HFD3_k127_1990863_3 Cysteine-rich secretory protein family - - - 0.00000000000000000000000004777 115.0
HFD3_k127_1991293_0 Heat shock 70 kDa protein K04043 - - 2.421e-234 734.0
HFD3_k127_1991293_1 Multicopper oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 437.0
HFD3_k127_1991293_2 PFAM Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007806 322.0
HFD3_k127_1991293_3 family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008132 314.0
HFD3_k127_1991293_4 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033,K15581 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 298.0
HFD3_k127_1991293_5 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034,K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002791 256.0
HFD3_k127_1991293_6 transcriptional regulator, Rrf2 family - - - 0.0000000000000000000000000000003237 128.0
HFD3_k127_1991293_7 phosphatidate phosphatase activity - - - 0.000000000000000000000001299 112.0
HFD3_k127_200202_0 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006533 548.0
HFD3_k127_200202_1 PFAM permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005529 455.0
HFD3_k127_200202_10 Putative zinc-finger - - - 0.0000000000004363 73.0
HFD3_k127_200202_11 Protein of unknown function (DUF2892) - - - 0.00000000007725 64.0
HFD3_k127_200202_12 - - - - 0.0000001229 63.0
HFD3_k127_200202_2 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 332.0
HFD3_k127_200202_3 Thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001847 236.0
HFD3_k127_200202_4 PFAM sigma-70 region 2 domain protein K03088 - - 0.0000000000000000000000000000000000000000001173 166.0
HFD3_k127_200202_5 nitrogen fixation - - - 0.000000000000000000000000000001873 124.0
HFD3_k127_200202_6 redox-active disulfide protein 2 - - - 0.0000000000000000000008904 97.0
HFD3_k127_200202_7 helix_turn_helix, Arsenical Resistance Operon Repressor K21903 - - 0.000000000000000000001626 99.0
HFD3_k127_200202_8 Protein of unknown function (DUF1634) - - - 0.0000000000000000004008 93.0
HFD3_k127_201153_0 Psort location Cytoplasmic, score K06971 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005239 312.0
HFD3_k127_201153_1 Xylose isomerase-like TIM barrel K03079 - 5.1.3.22 0.0000000000000000000000000000000000000000000000000000000000002411 222.0
HFD3_k127_201153_2 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K20257 - 3.1.2.32 0.00000000000000000000000000000000000000002823 162.0
HFD3_k127_201153_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000004893 134.0
HFD3_k127_201153_4 DeoR C terminal sensor domain - - - 0.000000000000001261 79.0
HFD3_k127_2015638_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 6.601e-201 634.0
HFD3_k127_2015638_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01840 - 5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009294 578.0
HFD3_k127_2015638_10 Belongs to the FPP GGPP synthase family K00805,K02523 - 2.5.1.30,2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003852 301.0
HFD3_k127_2015638_11 Glycosyl transferase family group 2 K07011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 293.0
HFD3_k127_2015638_12 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000144 295.0
HFD3_k127_2015638_13 hydrolase, TatD family K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000001759 243.0
HFD3_k127_2015638_14 WD40-like Beta Propeller Repeat K03641 - - 0.00000000000000000000000003071 122.0
HFD3_k127_2015638_15 Peptidase C14 caspase catalytic subunit p20 - - - 0.00000000000006872 76.0
HFD3_k127_2015638_16 KTSC domain - - - 0.00000001039 63.0
HFD3_k127_2015638_2 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 546.0
HFD3_k127_2015638_3 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007612 506.0
HFD3_k127_2015638_4 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006468,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008966,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019538,GO:0034641,GO:0034654,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046777,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008261 400.0
HFD3_k127_2015638_5 NAD(P)-binding Rossmann-like domain K00303 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003888 362.0
HFD3_k127_2015638_6 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 344.0
HFD3_k127_2015638_7 Polysaccharide biosynthesis protein K01711,K15856 - 1.1.1.281,4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008042 330.0
HFD3_k127_2015638_8 Belongs to the CinA family K03742 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 325.0
HFD3_k127_2015638_9 Proline dehydrogenase K00318 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007662 316.0
HFD3_k127_2054626_0 PFAM cytochrome c oxidase subunit II K00376 - 1.7.2.4 3.159e-267 835.0
HFD3_k127_2054626_1 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005783 388.0
HFD3_k127_2054626_2 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K02275 - 1.9.3.1 0.00000000000000000000000004498 115.0
HFD3_k127_2054626_3 lipoprotein involved in nitrous oxide reduction - - - 0.0000000000000000007235 93.0
HFD3_k127_2054626_4 - K02275,K17686 - 1.9.3.1,3.6.3.54 0.000000000000004128 85.0
HFD3_k127_2065517_0 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009454 455.0
HFD3_k127_2065517_1 DegT/DnrJ/EryC1/StrS aminotransferase family K10907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 409.0
HFD3_k127_2065517_2 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244 - 1.4.1.1,4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008796 378.0
HFD3_k127_2065517_3 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009932 247.0
HFD3_k127_2065517_4 nUDIX hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000007891 220.0
HFD3_k127_2065517_5 Belongs to the UPF0145 family - - - 0.00000000000000000000000000000000000000000001911 165.0
HFD3_k127_2065517_6 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 - 2.1.1.222,2.1.1.64 0.0003061 48.0
HFD3_k127_2068581_0 Caspase domain - - - 0.0000000000000000000000000003426 118.0
HFD3_k127_2068581_1 Caspase domain - - - 0.0002343 53.0
HFD3_k127_2072013_0 PFAM ABC-1 domain protein K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007023 503.0
HFD3_k127_2072013_1 creatininase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000006363 224.0
HFD3_k127_2072013_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000005874 96.0
HFD3_k127_207456_0 XanTHIne and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.0000000000000000000000000000000000000004977 160.0
HFD3_k127_207456_1 PFAM HD domain - - - 0.000000000000000000000000000000000001755 145.0
HFD3_k127_207456_2 formate dehydrogenase K00127 - - 0.00000000000000000000001816 113.0
HFD3_k127_207456_3 Formate hydrogenlyase K15827 - - 0.0000000000000000000001169 108.0
HFD3_k127_207456_4 - - - - 0.0000000000000000007476 99.0
HFD3_k127_207456_5 XdhC and CoxI family K07402 - - 0.000000000001207 75.0
HFD3_k127_207456_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000001749 55.0
HFD3_k127_207456_7 WD40-like Beta Propeller Repeat - - - 0.0000003048 60.0
HFD3_k127_2087415_0 PFAM Aldehyde dehydrogenase K00130,K00135 - 1.2.1.16,1.2.1.20,1.2.1.79,1.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009962 316.0
HFD3_k127_2087415_1 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 298.0
HFD3_k127_2099900_0 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.0000000000000000000000000000000000001956 149.0
HFD3_k127_2099900_1 TIGRFAM stage II sporulation protein D K06381 - - 0.00000000000000000002538 104.0
HFD3_k127_211651_0 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003299 252.0
HFD3_k127_211651_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000002093 242.0
HFD3_k127_211651_2 Arsenical pump-driving ATPase K01551 - 3.6.3.16 0.0000004852 53.0
HFD3_k127_211900_0 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 0.000000000000000000000000000000000002823 145.0
HFD3_k127_211900_1 cellulase activity - - - 0.000006955 58.0
HFD3_k127_2166268_0 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000007608 223.0
HFD3_k127_2166268_1 - - - - 0.00000000000000000000000001782 123.0
HFD3_k127_2166268_2 Glycosyl transferase, family 2 - - - 0.000000000000000000000002056 114.0
HFD3_k127_2176265_0 Nitrous oxide reductase K00376 - 1.7.2.4 9.375e-290 903.0
HFD3_k127_2176265_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000788 529.0
HFD3_k127_2176265_2 alginic acid biosynthetic process K07218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004631 371.0
HFD3_k127_2176265_3 with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine K01664 GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006575,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009108,GO:0009308,GO:0009309,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042398,GO:0042401,GO:0042430,GO:0042435,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003497 272.0
HFD3_k127_2176265_4 lipoprotein involved in nitrous oxide reduction K19342 - - 0.000000000000000000000000000000000000000000000000000000000005743 214.0
HFD3_k127_2176265_5 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000003701 193.0
HFD3_k127_2190176_0 PFAM beta-lactamase domain protein K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007983 455.0
HFD3_k127_2190176_1 ABC transporter transmembrane region K16012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 374.0
HFD3_k127_2190176_2 Cleaves the N-terminal amino acid of tripeptides K01258 - 3.4.11.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004908 361.0
HFD3_k127_2190176_3 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.00000000000000000000000000000000000000000000000000000001892 201.0
HFD3_k127_2190176_4 SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000007218 203.0
HFD3_k127_2190176_5 Rrf2 family - - - 0.0000000000000000000000000003134 122.0
HFD3_k127_2190176_7 SMART helix-turn-helix domain protein K15539 - - 0.00006135 55.0
HFD3_k127_219395_0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K03496 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000001251 217.0
HFD3_k127_219395_1 PFAM alpha beta hydrolase fold - - - 0.0000000000000000000000000000000005449 135.0
HFD3_k127_2194525_0 N-acetylglucosaminylinositol deacetylase activity K01463 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008117 382.0
HFD3_k127_2194525_1 Glycosyltransferase like family 2 K07011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001369 277.0
HFD3_k127_2194525_2 PFAM ROK family protein K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000001617 256.0
HFD3_k127_2194525_3 ROK family K00845,K13967,K19979,K20433 - 2.7.1.188,2.7.1.2,2.7.1.214,2.7.1.60,5.1.3.9 0.00000000000000000000000000000000000000000007671 162.0
HFD3_k127_2194525_4 Glycosyl transferase family group 2 K07011 - - 0.0000000000000000000000000000008366 124.0
HFD3_k127_227665_0 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III domain protein K01641 - 2.3.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 488.0
HFD3_k127_227665_1 Belongs to the HMG-CoA reductase family K00021,K00054 - 1.1.1.34,1.1.1.88 0.00000000000000000000000000000000000000696 147.0
HFD3_k127_227665_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000005415 61.0
HFD3_k127_230720_0 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002009 301.0
HFD3_k127_230720_1 PFAM Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000001373 102.0
HFD3_k127_2346804_0 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 8.497e-209 659.0
HFD3_k127_2346804_1 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 554.0
HFD3_k127_2346804_2 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007838 334.0
HFD3_k127_2346804_3 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000003245 145.0
HFD3_k127_2346804_4 PFAM LmbE family protein K18455 - 3.5.1.115 0.000000000000000000000000005786 120.0
HFD3_k127_2346804_5 Alpha/beta hydrolase family K03928 - 3.1.1.1 0.0008002 42.0
HFD3_k127_2350928_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 388.0
HFD3_k127_2350928_1 PFAM Rieske 2Fe-2S domain protein K02636 - 1.10.9.1 0.00000000000000000000003382 107.0
HFD3_k127_2350928_2 - - - - 0.0000000000002175 77.0
HFD3_k127_2350928_3 - - - - 0.0000000003245 65.0
HFD3_k127_23539_0 E1-E2 ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 2.635e-265 842.0
HFD3_k127_23539_1 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000308 417.0
HFD3_k127_23539_2 permease - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.0000000000000000000000000000000000000000000000000005147 199.0
HFD3_k127_23539_3 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000008302 183.0
HFD3_k127_23539_4 Cytochrome c K17222 - - 0.0000000000000000000000004508 116.0
HFD3_k127_23539_5 Metal-sensitive transcriptional repressor K21600 - - 0.000000000000000000000003115 104.0
HFD3_k127_23539_6 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.000000000000000004608 92.0
HFD3_k127_23539_7 pfam yhs - - - 0.000000000000001388 79.0
HFD3_k127_23539_8 Iron permease FTR1 family K07243 - - 0.00000000000575 76.0
HFD3_k127_2368903_0 Belongs to the formate--tetrahydrofolate ligase family K00288,K01938 GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.5.1.5,3.5.4.9,6.3.4.3 1.143e-272 852.0
HFD3_k127_2368903_1 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003798 287.0
HFD3_k127_2368903_2 PFAM Respiratory-chain NADH dehydrogenase 24 Kd subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000001699 180.0
HFD3_k127_2368903_3 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.0000000000000000000000000000047 123.0
HFD3_k127_2368903_4 Heavy-metal-associated domain K07213 - - 0.0000003136 57.0
HFD3_k127_2373208_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 1.907e-212 670.0
HFD3_k127_2373208_1 Elongation factor SelB, winged helix K03833 - - 2.891e-204 653.0
HFD3_k127_2373208_10 peptidase - - - 0.00000000005213 74.0
HFD3_k127_2373208_11 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.00000000009717 64.0
HFD3_k127_2373208_2 Spermine/spermidine synthase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 359.0
HFD3_k127_2373208_3 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000694 273.0
HFD3_k127_2373208_4 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000007444 236.0
HFD3_k127_2373208_5 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000001102 231.0
HFD3_k127_2373208_6 TIGRFAM signal peptidase I, bacterial type K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000003656 184.0
HFD3_k127_2373208_7 galactose-6-phosphate isomerase activity K00761,K01808 - 2.4.2.9,5.3.1.6 0.00000000000000000000000000000000000000000000002959 175.0
HFD3_k127_2373208_8 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.00000000000000000000000000000000004331 146.0
HFD3_k127_2373208_9 TIGRFAM integral membrane protein TIGR01906 - - - 0.000000000000000001826 93.0
HFD3_k127_2385999_0 Methylenetetrahydrofolate reductase K00297,K00547,K00548 - 1.5.1.20,2.1.1.10,2.1.1.13 2.403e-214 684.0
HFD3_k127_2385999_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004494 287.0
HFD3_k127_2393235_0 PFAM type II secretion system protein E K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 581.0
HFD3_k127_2393235_1 ATPase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 531.0
HFD3_k127_2393235_2 SMART ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 422.0
HFD3_k127_2393235_3 Winged helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 333.0
HFD3_k127_2393235_4 Two component transcriptional regulator, LuxR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 314.0
HFD3_k127_2393235_5 CoA-binding protein K06929 - - 0.0000000000000000000000000000000000003966 144.0
HFD3_k127_2393235_6 FAD dependent oxidoreductase - - - 0.0000000000000000000000003804 105.0
HFD3_k127_2393235_7 - - - - 0.00000000000000000000026 100.0
HFD3_k127_2393235_8 - - - - 0.000000000001237 73.0
HFD3_k127_2393235_9 Histidine kinase K07673 - 2.7.13.3 0.00000009516 54.0
HFD3_k127_2398810_0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease - - - 0.00000000000000000000000000000573 124.0
HFD3_k127_2398810_1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease - - - 0.0000000000000000000000000002716 128.0
HFD3_k127_2398810_2 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000001172 121.0
HFD3_k127_2398810_3 COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases K03641 - - 0.0000000000000000000000004736 117.0
HFD3_k127_2398810_4 von Willebrand factor, type A K07114 - - 0.00000000004252 75.0
HFD3_k127_2403729_0 WD40 repeats - - - 3.898e-248 807.0
HFD3_k127_2403729_1 SIR2-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 409.0
HFD3_k127_2403729_2 dihydropteroate synthase K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 364.0
HFD3_k127_2403729_3 Glycosyltransferase WbsX - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 327.0
HFD3_k127_2403729_4 PFAM GTP cyclohydrolase I Nitrile oxidoreductase K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000003521 247.0
HFD3_k127_2403729_5 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001032 236.0
HFD3_k127_2403729_6 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins K03769,K07533 - 5.2.1.8 0.000000000000000000000000000000000000008971 159.0
HFD3_k127_2403729_7 N-4 methylation of cytosine K00590 - 2.1.1.113 0.00000000000000000000006724 109.0
HFD3_k127_2411774_0 glyoxalase bleomycin resistance protein dioxygenase K15975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 418.0
HFD3_k127_2411774_1 DDE_Tnp_1-associated - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009317 258.0
HFD3_k127_2411774_2 Glycoside hydrolase family 3 domain protein K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000001063 220.0
HFD3_k127_2411774_3 required for the transposition of insertion element IS2404 - - - 0.00000000000000000000000000000000000000000000000000001308 203.0
HFD3_k127_2411774_4 transposase activity - - - 0.00000000000008372 83.0
HFD3_k127_242735_0 cellulose binding - - - 0.00000000000000000000000000000000000000000000000006604 205.0
HFD3_k127_242735_1 PFAM Formylglycine-generating sulfatase enzyme K18912 - 1.14.99.50 0.000000000000000001487 100.0
HFD3_k127_242735_2 - - - - 0.00000000000001095 89.0
HFD3_k127_242735_3 Acetyltransferase (GNAT) domain - - - 0.00000000125 60.0
HFD3_k127_2431325_0 solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007336 436.0
HFD3_k127_2431325_1 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004514 396.0
HFD3_k127_2431325_2 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 366.0
HFD3_k127_2431325_3 Binding-protein-dependent transport system inner membrane component K02025,K10118,K15771 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 342.0
HFD3_k127_2431325_4 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 337.0
HFD3_k127_2431325_5 ROK family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000456 336.0
HFD3_k127_2431325_6 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008164 312.0
HFD3_k127_2432829_0 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 510.0
HFD3_k127_2432829_1 PFAM thiamine pyrophosphate protein domain protein TPP-binding K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005679 322.0
HFD3_k127_2432829_2 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.000000000001975 67.0
HFD3_k127_2432829_3 PFAM Protein kinase domain K08884 - 2.7.11.1 0.000000000004851 77.0
HFD3_k127_2432829_4 Regulatory protein, FmdB family - - - 0.00000000466 61.0
HFD3_k127_2437891_0 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 580.0
HFD3_k127_2437891_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 500.0
HFD3_k127_2437891_2 PFAM acyl-CoA dehydrogenase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003689 460.0
HFD3_k127_2437891_3 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K00015,K18916 - 1.1.1.26,1.20.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006369 417.0
HFD3_k127_2437891_4 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000001463 229.0
HFD3_k127_2437891_5 Histidine triad (HIT) protein K19710 - 2.7.7.53 0.0000000000000000000000000000000000000000000000000000001764 199.0
HFD3_k127_2437891_6 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000005562 200.0
HFD3_k127_2437891_7 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 0.00000000000000000000000003642 111.0
HFD3_k127_2442614_0 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000003515 228.0
HFD3_k127_2442614_1 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000001283 198.0
HFD3_k127_2442614_2 ABC-type multidrug transport system, permease component K01992 - - 0.00000000000000000000000000000001393 134.0
HFD3_k127_2442726_0 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 424.0
HFD3_k127_2442726_1 TIGRFAM glycosyltransferase, MGT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004848 275.0
HFD3_k127_2442726_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000005961 256.0
HFD3_k127_2442726_3 COG1228 Imidazolonepropionase and related amidohydrolases - - - 0.000000000000000000000000000000000000000000000000000259 197.0
HFD3_k127_2442726_4 ATP diphosphatase activity - - - 0.00000000000000000000000000000000000000000000004853 183.0
HFD3_k127_2442726_5 Nitroreductase family - - - 0.00000000000000000000000000000000000000001732 163.0
HFD3_k127_244373_0 Belongs to the ClpA ClpB family K03694 - - 1.237e-295 927.0
HFD3_k127_244373_1 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 6.462e-242 768.0
HFD3_k127_244373_10 - - - - 0.00000000000000000000006517 108.0
HFD3_k127_244373_11 YtxH-like protein - - - 0.0007114 47.0
HFD3_k127_244373_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009718 512.0
HFD3_k127_244373_3 PFAM peptidase S1 and S6, chymotrypsin Hap K04771,K08070 - 1.3.1.74,3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 366.0
HFD3_k127_244373_4 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004442 307.0
HFD3_k127_244373_5 Catechol dioxygenase N terminus K03381 - 1.13.11.1 0.0000000000000000000000000000000000000000000000000000000000001272 221.0
HFD3_k127_244373_6 Electron transfer flavoprotein K03522 - - 0.0000000000000000000000000000000000000000000000000000009849 203.0
HFD3_k127_244373_7 YceI-like domain - - - 0.00000000000000000000000000000000000000000005537 171.0
HFD3_k127_244373_8 Electron transfer flavoprotein domain K03521 - - 0.0000000000000000000000000000000000000000007371 163.0
HFD3_k127_244373_9 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896,GO:0051087 - 0.00000000000000000000000000000002057 128.0
HFD3_k127_2447345_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 5.786e-213 672.0
HFD3_k127_2447345_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 3.965e-209 658.0
HFD3_k127_2447345_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005028 263.0
HFD3_k127_2447345_3 Peptidoglycan-binding LysM - - - 0.0000000000000000000000000000000000000000000000000000000000007017 224.0
HFD3_k127_2447345_4 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000001515 169.0
HFD3_k127_2447345_5 Psort location CytoplasmicMembrane, score K00368 - 1.7.2.1 0.00000000000000000000000000000000000000001258 172.0
HFD3_k127_2447345_6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110,K02124 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042802,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000002622 102.0
HFD3_k127_2447345_7 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000002404 97.0
HFD3_k127_2447345_8 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000001273 97.0
HFD3_k127_2456326_0 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01895 - 6.2.1.1 6.64e-253 791.0
HFD3_k127_2456326_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008928 554.0
HFD3_k127_2456326_10 protein homooligomerization K08086 - - 0.000000000000005688 83.0
HFD3_k127_2456326_2 Aminotransferase K00812,K10907 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000496 545.0
HFD3_k127_2456326_3 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 530.0
HFD3_k127_2456326_4 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008186 490.0
HFD3_k127_2456326_5 - - - - 0.00000000000000000000000000000003889 140.0
HFD3_k127_2456326_6 RAB23, member RAS oncogene family K06234 GO:0000045,GO:0001501,GO:0001738,GO:0001838,GO:0001841,GO:0001843,GO:0002009,GO:0003002,GO:0003674,GO:0003824,GO:0003924,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005773,GO:0005776,GO:0005813,GO:0005815,GO:0005829,GO:0005856,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006914,GO:0006950,GO:0006952,GO:0006968,GO:0006996,GO:0007033,GO:0007154,GO:0007165,GO:0007264,GO:0007265,GO:0007275,GO:0007389,GO:0007399,GO:0007417,GO:0008150,GO:0008152,GO:0008589,GO:0009056,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009653,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009892,GO:0009953,GO:0009966,GO:0009987,GO:0010008,GO:0010605,GO:0010646,GO:0012505,GO:0014020,GO:0015630,GO:0016020,GO:0016043,GO:0016192,GO:0016236,GO:0016331,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019222,GO:0019637,GO:0019693,GO:0021510,GO:0021511,GO:0021513,GO:0021532,GO:0021904,GO:0021915,GO:0022607,GO:0023051,GO:0023052,GO:0030030,GO:0030031,GO:0030054,GO:0030139,GO:0030162,GO:0030326,GO:0031090,GO:0031323,GO:0031324,GO:0031410,GO:0031982,GO:0032268,GO:0032269,GO:0032386,GO:0032387,GO:0032482,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0033157,GO:0034641,GO:0035107,GO:0035108,GO:0035113,GO:0035148,GO:0035239,GO:0035295,GO:0035556,GO:0036477,GO:0042278,GO:0042306,GO:0042308,GO:0042733,GO:0043009,GO:0043025,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044297,GO:0044422,GO:0044424,GO:0044430,GO:0044433,GO:0044440,GO:0044444,GO:0044446,GO:0044464,GO:0044782,GO:0045202,GO:0045335,GO:0045861,GO:0046039,GO:0046128,GO:0046483,GO:0046822,GO:0046823,GO:0048513,GO:0048519,GO:0048523,GO:0048583,GO:0048598,GO:0048646,GO:0048705,GO:0048729,GO:0048731,GO:0048736,GO:0048856,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051051,GO:0051171,GO:0051172,GO:0051179,GO:0051223,GO:0051224,GO:0051234,GO:0051246,GO:0051248,GO:0051716,GO:0055086,GO:0060173,GO:0060255,GO:0060271,GO:0060341,GO:0060348,GO:0060349,GO:0060429,GO:0060562,GO:0060606,GO:0061919,GO:0065007,GO:0070201,GO:0070925,GO:0071704,GO:0071840,GO:0071944,GO:0072175,GO:0072521,GO:0080090,GO:0090087,GO:0090317,GO:0097094,GO:0097458,GO:0097708,GO:0098588,GO:0098805,GO:0120031,GO:0120036,GO:1900180,GO:1900181,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657,GO:1903827,GO:1903828,GO:1904589,GO:1904590,GO:1904888,GO:1904950,GO:1905037 - 0.00000000000000000000000000003298 124.0
HFD3_k127_2456326_7 - - - - 0.000000000000000000000001106 106.0
HFD3_k127_2456326_8 PFAM aspartate glutamate uridylate kinase K00931,K03430,K06981 - 2.6.1.37,2.7.2.11,2.7.4.26 0.00000000000000000001583 94.0
HFD3_k127_2456326_9 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.0000000000000000003705 88.0
HFD3_k127_2460505_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 471.0
HFD3_k127_2460505_1 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 475.0
HFD3_k127_2460505_10 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000001506 141.0
HFD3_k127_2460505_11 PFAM Transglycosylase-associated protein - - - 0.000000000000000000001826 98.0
HFD3_k127_2460505_12 - - - - 0.0000000001119 62.0
HFD3_k127_2460505_13 DEAD DEAH box helicase domain protein K06877 - - 0.0002886 51.0
HFD3_k127_2460505_2 Phage plasmid primase, P4 K06919 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006026 362.0
HFD3_k127_2460505_3 PFAM peptidase T2 asparaginase 2 K13051 - 3.4.19.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005568 309.0
HFD3_k127_2460505_4 glycerophosphodiester transmembrane transport K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000003822 242.0
HFD3_k127_2460505_5 Binding-protein-dependent transport system inner membrane component K02025 - - 0.00000000000000000000000000000000000000000000000000000000000007411 228.0
HFD3_k127_2460505_6 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) K01788 - 5.1.3.9 0.00000000000000000000000000000000000000000000000000000000001756 214.0
HFD3_k127_2460505_7 Transposase IS200 like - - - 0.000000000000000000000000000000000000000000000000002109 192.0
HFD3_k127_2460505_8 BadF BadG BcrA BcrD - GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006040,GO:0006044,GO:0006082,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0045127,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901071,GO:1901135,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000001634 192.0
HFD3_k127_2460505_9 PFAM Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000004266 187.0
HFD3_k127_2469399_0 KR domain K00065 - 1.1.1.127 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004324 310.0
HFD3_k127_2469399_1 VIT family - - - 0.000000000000000000000000000000000000003613 147.0
HFD3_k127_2481567_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 385.0
HFD3_k127_2481567_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006184 307.0
HFD3_k127_2481567_2 Methionine synthase B12-binding module cap domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004401 261.0
HFD3_k127_2481567_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000005233 130.0
HFD3_k127_2481567_4 amine dehydrogenase activity K19668,K20276 - 3.2.1.91 0.00000000000892 73.0
HFD3_k127_2481946_0 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 302.0
HFD3_k127_2481946_1 FCD - - - 0.000000000001381 69.0
HFD3_k127_2483830_0 lipid A export permease ATP-binding protein MsbA K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 328.0
HFD3_k127_2483830_1 Bacterial sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000275 268.0
HFD3_k127_2483830_2 Protein of unknown function (DUF4012) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004765 272.0
HFD3_k127_2483830_3 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000003173 203.0
HFD3_k127_2483830_4 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.000000000000000000000000000000000000000000000004383 195.0
HFD3_k127_2483830_5 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000001178 108.0
HFD3_k127_2483830_6 polysaccharide biosynthetic process K03379 - 1.14.13.22 0.0000000000000000000119 105.0
HFD3_k127_2502366_0 PFAM Exonuclease, RNase T and DNA polymerase III K02342,K03722 - 2.7.7.7,3.6.4.12 4.449e-255 817.0
HFD3_k127_2502366_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007892 351.0
HFD3_k127_2502366_10 - - - - 0.00000005421 60.0
HFD3_k127_2502366_2 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001407 257.0
HFD3_k127_2502366_3 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000000001528 237.0
HFD3_k127_2502366_4 diguanylate cyclase K02488 - 2.7.7.65 0.000000000000000000000000000000000001671 149.0
HFD3_k127_2502366_5 tRNA nucleotidyltransferase poly(A) polymerase K00974 - 2.7.7.72 0.000000000000000000008451 100.0
HFD3_k127_2502366_6 Protein of unknown function (DUF1572) - - - 0.0000000000000000002524 93.0
HFD3_k127_2502366_7 Acyl-ACP thioesterase K01071 - 3.1.2.21 0.000000000001226 78.0
HFD3_k127_2502366_8 - - - - 0.00000000000936 73.0
HFD3_k127_2502366_9 - - - - 0.000000005525 67.0
HFD3_k127_2514603_0 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 302.0
HFD3_k127_2514603_1 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005883 279.0
HFD3_k127_2514603_2 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.00000000000000000000000000000000000000000000000000000000000000006346 235.0
HFD3_k127_2514603_3 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000001078 188.0
HFD3_k127_2514603_4 Molybdopterin-binding domain of aldehyde dehydrogenase K20448 - 1.17.1.5 0.000000000000000000000005104 103.0
HFD3_k127_2528187_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1165.0
HFD3_k127_2528187_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004211 271.0
HFD3_k127_2533152_0 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000001332 271.0
HFD3_k127_2533152_1 Sodium/calcium exchanger protein K07300 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015085,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015368,GO:0015369,GO:0015491,GO:0015672,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051139,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:0099516,GO:1902600 - 0.000000000000000000000000000000000000000000000000000000000000000000000005655 254.0
HFD3_k127_2533152_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.0000000000000000000000000000000000000000000000000000000000003254 220.0
HFD3_k127_2533152_3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000003864 197.0
HFD3_k127_2533152_4 Competence protein ComEA K02237 - - 0.00000000000000000000000000000000002653 143.0
HFD3_k127_2533152_5 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000001254 135.0
HFD3_k127_2533152_6 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000002573 64.0
HFD3_k127_2533152_7 - - - - 0.00005685 54.0
HFD3_k127_2569913_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 1.703e-283 888.0
HFD3_k127_2569913_1 Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde K00656,K07540,K18427 - 2.3.1.54,4.1.1.83,4.1.99.11 1.194e-209 668.0
HFD3_k127_2569913_2 methionine synthase K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000001733 244.0
HFD3_k127_2569913_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00124,K07307 - - 0.00000000000000000000000000000000000001204 151.0
HFD3_k127_2569913_4 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000002125 55.0
HFD3_k127_2572716_0 Binding-protein-dependent transport system inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000493 407.0
HFD3_k127_2572716_1 ATPases associated with a variety of cellular activities K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009013 368.0
HFD3_k127_2572716_2 Bacterial extracellular solute-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000008808 243.0
HFD3_k127_2572716_3 Haloacid dehalogenase-like hydrolase K07025 - - 0.00000000000000000000000000000000000000000000008516 177.0
HFD3_k127_2577336_0 DEAD DEAH box helicase domain protein K06877 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007245 521.0
HFD3_k127_2577336_1 helicase superfamily c-terminal domain K06877 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004717 259.0
HFD3_k127_2577336_2 RNase_H superfamily K07502 - - 0.000000000000000000006809 100.0
HFD3_k127_2582034_0 Acyl-CoA dehydrogenase, N-terminal domain K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 400.0
HFD3_k127_2582034_2 - - - - 0.0000001656 58.0
HFD3_k127_2604270_0 ATPase AAA-2 domain protein K03696 - - 0.0 1022.0
HFD3_k127_2604270_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005809 505.0
HFD3_k127_2604270_2 Ribosomal protein S1 K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 398.0
HFD3_k127_2604270_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006234 277.0
HFD3_k127_2604270_4 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255,K01259 GO:0001073,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006351,GO:0006355,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009056,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016787,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019538,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042150,GO:0043170,GO:0043171,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043244,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0097718,GO:0140096,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1903506,GO:2000112,GO:2001141 3.4.11.1,3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000002165 231.0
HFD3_k127_2604270_5 NUDIX domain - - - 0.000000000000000000000000000000000000000272 155.0
HFD3_k127_2609685_0 DJ-1/PfpI family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005024 503.0
HFD3_k127_2609685_1 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000504 312.0
HFD3_k127_2609685_2 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002419 243.0
HFD3_k127_2609685_3 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000000000000000000000000000000147 235.0
HFD3_k127_2609685_4 reductase - - - 0.0000000000000000000000000000000000000000000000000001908 187.0
HFD3_k127_2609685_5 Pyridoxamine 5'-phosphate oxidase - - - 0.000000000000000000000000000000000000000001626 161.0
HFD3_k127_2609685_6 RibD C-terminal domain - - - 0.00001003 50.0
HFD3_k127_2616232_0 ABC-type multidrug transport system ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 344.0
HFD3_k127_2616232_1 ABC-2 family transporter protein - - - 0.0000000000000000000000000000000000001464 150.0
HFD3_k127_2616232_2 AntiSigma factor - - - 0.00000000001693 70.0
HFD3_k127_2651666_0 Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX K17759 - 5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000001117 250.0
HFD3_k127_2651666_1 Belongs to the SOS response-associated peptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000004698 236.0
HFD3_k127_2651666_2 mercury ion transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000001483 199.0
HFD3_k127_2677391_0 Belongs to the citrate synthase family K01647 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006532 463.0
HFD3_k127_2677391_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 388.0
HFD3_k127_2677391_10 NADPH:quinone reductase activity - - - 0.0000000000000003083 81.0
HFD3_k127_2677391_12 dephospho-CoA kinase activity - - - 0.0000001406 63.0
HFD3_k127_2677391_2 Belongs to the ABC transporter superfamily K02017 - 3.6.3.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 348.0
HFD3_k127_2677391_3 Amidinotransferase K01482 - 3.5.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005617 300.0
HFD3_k127_2677391_4 Binding-protein-dependent transport system inner membrane component K02018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004882 263.0
HFD3_k127_2677391_5 Bacterial extracellular solute-binding protein K02020 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002995 260.0
HFD3_k127_2677391_6 DUF218 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001947 237.0
HFD3_k127_2677391_7 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000003564 180.0
HFD3_k127_2677391_8 - - - - 0.00000000000000000000000000000000000000000006207 166.0
HFD3_k127_2677391_9 PFAM transcriptional regulator PadR family protein - - - 0.00000000000000000000000002706 117.0
HFD3_k127_2687590_0 Stage II sporulation E family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 617.0
HFD3_k127_2687590_1 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 454.0
HFD3_k127_2687590_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000781 277.0
HFD3_k127_2687590_3 antisigma factor binding K04749 - - 0.00000000000000000000000000000004141 129.0
HFD3_k127_27192_0 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 451.0
HFD3_k127_27192_1 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 447.0
HFD3_k127_27192_2 PFAM thymidine kinase K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001912 271.0
HFD3_k127_27192_3 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.00000000000000000000000000000002722 127.0
HFD3_k127_27192_4 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000000000000005865 110.0
HFD3_k127_27192_5 Ribosomal protein L31 K02909 - - 0.0000000000000000000000006148 112.0
HFD3_k127_27192_6 Preprotein translocase SecG subunit K03075 - - 0.00000000004691 66.0
HFD3_k127_2721456_0 Creatinine amidohydrolase K01470,K22232 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006796 362.0
HFD3_k127_2721456_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 GO:0000255,GO:0000256,GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008679,GO:0009056,GO:0009436,GO:0009442,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042737,GO:0043436,GO:0043603,GO:0043605,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046185,GO:0046395,GO:0046483,GO:0046487,GO:0046700,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003297 360.0
HFD3_k127_2721456_2 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 349.0
HFD3_k127_2721456_3 formate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004015 308.0
HFD3_k127_2721456_4 Xylose isomerase-like TIM barrel K22233 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003055 267.0
HFD3_k127_2722828_0 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.0 1042.0
HFD3_k127_2722828_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.0 1035.0
HFD3_k127_2722828_10 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000005156 210.0
HFD3_k127_2722828_11 amino acid K03294 - - 0.000000000000000000000000000000002944 133.0
HFD3_k127_2722828_12 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000005695 116.0
HFD3_k127_2722828_13 heme binding - - - 0.0000000000000000000000001231 119.0
HFD3_k127_2722828_14 domain, Protein - - - 0.000000000000000000000001107 121.0
HFD3_k127_2722828_15 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000001329 64.0
HFD3_k127_2722828_16 Domain of unknown function (DUF4340) - - - 0.000000007473 65.0
HFD3_k127_2722828_17 heme oxygenase (decyclizing) activity - - - 0.000001957 55.0
HFD3_k127_2722828_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031004,GO:0031224,GO:0031226,GO:0031420,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 5.047e-259 811.0
HFD3_k127_2722828_3 WD domain, G-beta repeat - - - 2.261e-232 772.0
HFD3_k127_2722828_4 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005568 530.0
HFD3_k127_2722828_5 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 344.0
HFD3_k127_2722828_6 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005066 316.0
HFD3_k127_2722828_7 transport system involved in gliding motility, auxiliary K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 304.0
HFD3_k127_2722828_8 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000005898 266.0
HFD3_k127_2722828_9 Histidine kinase K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000049 246.0
HFD3_k127_2730286_0 Chitinase class I K03791 - - 0.000000000000000000000000000001896 133.0
HFD3_k127_2730286_1 - - - - 0.000000000000001029 86.0
HFD3_k127_2730286_2 Helix-turn-helix domain - - - 0.0003777 48.0
HFD3_k127_2734283_0 ROK family K00845,K00847 - 2.7.1.2,2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 430.0
HFD3_k127_2734283_1 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 310.0
HFD3_k127_2734283_2 ABC-type sugar transport system periplasmic component K02081,K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005537 277.0
HFD3_k127_2758292_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 567.0
HFD3_k127_2758292_1 Histidine ammonia-lyase K01745 - 4.3.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 470.0
HFD3_k127_2758292_10 Metal dependent phosphohydrolases with conserved 'HD' motif. K09163 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001013 259.0
HFD3_k127_2758292_11 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008283 258.0
HFD3_k127_2758292_12 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000008811 213.0
HFD3_k127_2758292_13 SMART Tetratricopeptide domain protein - - - 0.00000000000000000000000000000000000000000000000000000009719 220.0
HFD3_k127_2758292_14 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000002309 209.0
HFD3_k127_2758292_15 Bacterial membrane protein, YfhO - - - 0.0000000000000000000000000000000000000000000000000002644 213.0
HFD3_k127_2758292_16 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000004319 184.0
HFD3_k127_2758292_17 chromate transporter K07240 - - 0.0000000000000000000000000000000007687 137.0
HFD3_k127_2758292_18 TIGRFAM phosphoesterase, MJ0936 family K07095 - - 0.00000000000000000000000000000002358 132.0
HFD3_k127_2758292_19 Cysteine-rich secretory protein family - - - 0.00000000000000000000000002425 123.0
HFD3_k127_2758292_2 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004915 458.0
HFD3_k127_2758292_20 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000003145 115.0
HFD3_k127_2758292_21 amine dehydrogenase activity - - - 0.000000000000000004745 100.0
HFD3_k127_2758292_22 PFAM Cysteine-rich secretory protein family - - - 0.00000000000000007022 92.0
HFD3_k127_2758292_23 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000005997 70.0
HFD3_k127_2758292_24 cellulose binding - - - 0.000000000002087 81.0
HFD3_k127_2758292_26 - - - - 0.000001444 58.0
HFD3_k127_2758292_27 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.000018 56.0
HFD3_k127_2758292_3 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007851 423.0
HFD3_k127_2758292_4 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008286 372.0
HFD3_k127_2758292_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 324.0
HFD3_k127_2758292_6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 308.0
HFD3_k127_2758292_7 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000359 270.0
HFD3_k127_2758292_8 PFAM YbbR family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003388 272.0
HFD3_k127_2758292_9 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000255 261.0
HFD3_k127_2826642_0 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009205 462.0
HFD3_k127_2826642_1 amidohydrolase K21613 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 349.0
HFD3_k127_2826642_2 PFAM Papain family cysteine protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006289 297.0
HFD3_k127_2826642_3 Glycosyl hydrolase family 30 TIM-barrel domain - - - 0.0000000000000000000000000000000000000000313 173.0
HFD3_k127_2826642_4 serine-type aminopeptidase activity K02030,K14475 - - 0.00000000000000000001799 94.0
HFD3_k127_2826642_5 N-acetylmuramoyl-L-alanine amidase - - - 0.00000000001199 78.0
HFD3_k127_2830480_0 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 433.0
HFD3_k127_2830480_1 Stage II sporulation K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 405.0
HFD3_k127_2830480_2 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003737 303.0
HFD3_k127_2830480_3 PAS domain - - - 0.0000000000000000000000000000000000002331 145.0
HFD3_k127_2830480_4 Response regulator receiver - - - 0.000000000000000000000000002267 111.0
HFD3_k127_2830480_5 TIGRFAM geranylgeranyl reductase - - - 0.00000000001533 73.0
HFD3_k127_2830480_6 LysM domain - - - 0.000000002478 65.0
HFD3_k127_2851916_0 acetylesterase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002077 264.0
HFD3_k127_2851916_1 PFAM LmbE family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000723 257.0
HFD3_k127_2851916_2 - - - - 0.00000000000000000000000000000002416 126.0
HFD3_k127_2851916_3 - - - - 0.0000000000000000003989 94.0
HFD3_k127_2851916_5 - - - - 0.0000006561 56.0
HFD3_k127_289005_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 0.0 1182.0
HFD3_k127_289005_1 PFAM Anion-transporting ATPase K01551 - 3.6.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 459.0
HFD3_k127_289005_10 peptidyl-tyrosine sulfation - - - 0.000000003474 68.0
HFD3_k127_289005_11 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000005295 57.0
HFD3_k127_289005_12 Type IV pilus biogenesis stability protein PilW - - - 0.000001044 60.0
HFD3_k127_289005_2 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 387.0
HFD3_k127_289005_3 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009736 374.0
HFD3_k127_289005_4 metal-dependent phosphohydrolase HD region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 319.0
HFD3_k127_289005_5 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000002432 226.0
HFD3_k127_289005_6 ABC transporter (Permease K01999 - - 0.00000000000000000000000000000000001305 142.0
HFD3_k127_289005_7 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000002731 139.0
HFD3_k127_289005_8 Protein of unknown function (DUF2723) K14340 - - 0.00000000000000000000000000000003141 146.0
HFD3_k127_289005_9 Diguanylate cyclase - - - 0.00000000000000000001005 106.0
HFD3_k127_2934465_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 551.0
HFD3_k127_2934465_1 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07668,K07775 - - 0.000000000000000000000000000000000000000000000000000396 194.0
HFD3_k127_2934465_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07636 - 2.7.13.3 0.0000000000000000000000000000000007102 151.0
HFD3_k127_2934465_3 His Kinase A (phosphoacceptor) domain K11527 - 2.7.13.3 0.0000000002197 74.0
HFD3_k127_2950120_0 similarity to SP Q08346 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001786 271.0
HFD3_k127_2950120_1 AAA domain K07505 - - 0.000000000000000000000000000000000000000000003334 183.0
HFD3_k127_2960423_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 2.161e-310 970.0
HFD3_k127_297494_0 metallopeptidase activity K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005642 425.0
HFD3_k127_297494_1 Putative modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006257 382.0
HFD3_k127_2981572_0 involved in cell wall biogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000000001515 228.0
HFD3_k127_2981572_1 Psort location CytoplasmicMembrane, score K09153 - - 0.000000000157 67.0
HFD3_k127_2981572_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00002835 52.0
HFD3_k127_301368_0 beta-glucosidase activity K05350,K21000 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006993 361.0
HFD3_k127_301368_1 Belongs to the N(4) N(6)-methyltransferase family K00590 - 2.1.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005974 290.0
HFD3_k127_301368_2 ECF transporter, substrate-specific component - - - 0.00000000000000000000000000000003793 135.0
HFD3_k127_3040502_0 PFAM fumarate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004264 521.0
HFD3_k127_3040502_1 ArgJ family K00620,K00930 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35,2.7.2.8 0.0000000000000000000000000000000000000000000000001766 180.0
HFD3_k127_3105782_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007493 381.0
HFD3_k127_3105782_1 Belongs to the TtcA family K21947 - 2.8.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 305.0
HFD3_k127_3105782_2 glutamine synthetase K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000001047 195.0
HFD3_k127_3105782_3 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000008248 199.0
HFD3_k127_3105782_4 thiamine diphosphate biosynthetic process K03154 - - 0.000004329 51.0
HFD3_k127_3108755_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 561.0
HFD3_k127_3108755_1 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 447.0
HFD3_k127_3108755_2 COG1960 Acyl-CoA dehydrogenases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005164 402.0
HFD3_k127_3108755_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000009367 244.0
HFD3_k127_3108755_4 B12 binding domain K01849 - 5.4.99.2 0.000000000000000000000000000000000000000019 156.0
HFD3_k127_3108755_5 Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.0000000000000000000004188 102.0
HFD3_k127_3113374_0 PFAM formate-tetrahydrofolate ligase FTHFS K01938 - 6.3.4.3 4.532e-248 779.0
HFD3_k127_3113374_1 Copper resistance protein CopC K14166 - - 0.000000000000000000000000000000000000000000000000000000000000000000002538 263.0
HFD3_k127_3113374_2 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000002882 261.0
HFD3_k127_3113374_3 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000008014 241.0
HFD3_k127_3113374_4 PFAM Formiminotransferase-cyclodeaminase - - - 0.00000000000000000000000000000000000000000007555 168.0
HFD3_k127_3113374_5 Predicted membrane protein (DUF2085) - - - 0.0000000000000000000000000000000000000002413 159.0
HFD3_k127_3113374_6 COG0671 Membrane-associated phospholipid phosphatase K19302 - 3.6.1.27 0.000000000000000000001648 101.0
HFD3_k127_3113374_7 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.0000000000000000000146 93.0
HFD3_k127_3121159_0 PFAM Acetyltransferase (GNAT) family K06976 - - 0.00000000000000000000000000000000000000000000000000000000000000000002043 243.0
HFD3_k127_3121159_1 Peptidase s1 and s6 chymotrypsin hap K08372 - - 0.00000000005184 71.0
HFD3_k127_3121159_2 NurA - - - 0.000005543 54.0
HFD3_k127_3131797_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016465,GO:0018995,GO:0020003,GO:0023051,GO:0023056,GO:0030430,GO:0032991,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0051082,GO:0061077,GO:0065007,GO:0065010,GO:0101031,GO:1901222,GO:1901224,GO:1902531,GO:1902533,GO:1990220,GO:2000535 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008945 539.0
HFD3_k127_3131797_1 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000001254 129.0
HFD3_k127_3131797_2 Membrane - - - 0.000000000000001105 79.0
HFD3_k127_3131797_3 peptidyl-tyrosine sulfation - - - 0.0000000000000112 86.0
HFD3_k127_3139079_0 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000001677 147.0
HFD3_k127_3139079_1 - - - - 0.0000000000000000000000000000002869 127.0
HFD3_k127_3139079_2 Protein of unknown function (DUF2089) - - - 0.000000000000000000000000003764 115.0
HFD3_k127_3139079_3 mannose-6-phosphate isomerase K01809 - 5.3.1.8 0.000000003551 61.0
HFD3_k127_3140889_0 Multicopper oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 390.0
HFD3_k127_3140889_1 amino acid K16263 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000244 278.0
HFD3_k127_3140889_10 Protein of unknown function (DUF1697) - - - 0.000003276 55.0
HFD3_k127_3140889_11 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000009475 49.0
HFD3_k127_3140889_12 Berberine and berberine like - - - 0.0001691 49.0
HFD3_k127_3140889_2 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0017144,GO:0018130,GO:0019752,GO:0032259,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.197 0.000000000000000000000000000000000000000000000000000000000000000002543 235.0
HFD3_k127_3140889_3 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000000000000000001065 210.0
HFD3_k127_3140889_4 - - - - 0.000000000000000000000000000000000000000000000000002424 186.0
HFD3_k127_3140889_5 bis(5'-adenosyl)-triphosphatase activity - - - 0.00000000000000000000000000000000000000000436 160.0
HFD3_k127_3140889_6 phosphoenolpyruvate synthase K01007 - 2.7.9.2 0.0000000000000000121 83.0
HFD3_k127_3140889_7 Domain of unknown function (DUF4345) - - - 0.00000000000001169 80.0
HFD3_k127_3140889_8 Acetyltransferase (GNAT) domain - - - 0.000000002107 64.0
HFD3_k127_3140889_9 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000269 55.0
HFD3_k127_3143967_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005121 449.0
HFD3_k127_3143967_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003085 428.0
HFD3_k127_3143967_10 POTRA domain, FtsQ-type K03589 - - 0.0001828 53.0
HFD3_k127_3143967_2 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004813 413.0
HFD3_k127_3143967_3 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 400.0
HFD3_k127_3143967_4 TIGRFAM cell division protein FtsW K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 298.0
HFD3_k127_3143967_5 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004409 274.0
HFD3_k127_3143967_6 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000008993 261.0
HFD3_k127_3143967_7 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000004236 242.0
HFD3_k127_3143967_8 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000318 186.0
HFD3_k127_3143967_9 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000005592 73.0
HFD3_k127_3152086_0 carboxylic acid catabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000001477 224.0
HFD3_k127_3152086_1 metal-dependent phosphohydrolase, HD sub domain K07037 - - 0.000000000000000000000000000000000000001075 164.0
HFD3_k127_3152086_2 Glycoside hydrolase, family 19 K03791 - - 0.0000005189 53.0
HFD3_k127_3152086_3 cellulase activity - - - 0.000002754 58.0
HFD3_k127_3156785_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 1.813e-225 711.0
HFD3_k127_3156785_1 Catalyzes the attachment of glycine to tRNA(Gly) K01880 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 556.0
HFD3_k127_3156785_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 419.0
HFD3_k127_3156785_3 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001991 282.0
HFD3_k127_3156785_4 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000000000000000000000853 220.0
HFD3_k127_3156785_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000007491 167.0
HFD3_k127_3156785_6 cytidine deaminase activity K01489 GO:0001882,GO:0001884,GO:0003674,GO:0003824,GO:0004126,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006216,GO:0006217,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008655,GO:0009056,GO:0009058,GO:0009116,GO:0009119,GO:0009120,GO:0009164,GO:0009972,GO:0009987,GO:0015949,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0036094,GO:0042454,GO:0042802,GO:0043094,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046087,GO:0046092,GO:0046121,GO:0046125,GO:0046127,GO:0046131,GO:0046133,GO:0046135,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0047844,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0097159,GO:0097367,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.5.4.5 0.000000000000000000000000000000003131 133.0
HFD3_k127_3156785_7 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000004689 96.0
HFD3_k127_3156785_8 Mazg nucleotide pyrophosphohydrolase - - - 0.00000003641 59.0
HFD3_k127_3158271_0 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005482 427.0
HFD3_k127_3158271_1 PFAM oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 312.0
HFD3_k127_3158271_2 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000001056 125.0
HFD3_k127_3164805_0 2-methylcitrate dehydratase K01720 - 4.2.1.79 1.378e-197 626.0
HFD3_k127_3164805_1 (2R)-phospho-3-sulfolactate synthase (ComA) K08097 - 4.4.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006985 442.0
HFD3_k127_3164805_2 COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes - - - 0.00000000000000000000000000000000000001378 147.0
HFD3_k127_3164805_3 Protein of unknown function (DUF1706) - - - 0.000000000000000000000000000001256 124.0
HFD3_k127_3174236_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007065 602.0
HFD3_k127_3174236_1 6-phosphogluconolactonase K01057 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 3.1.1.31 0.0000000000000000000000000000000000000000000000004832 188.0
HFD3_k127_3174545_0 Belongs to the serpin family K13963 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 345.0
HFD3_k127_3174545_1 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000000000000001026 181.0
HFD3_k127_3174545_2 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.00000000000000000000008274 97.0
HFD3_k127_3174545_3 His Kinase A (phosphoacceptor) domain K10819 - 2.7.13.3 0.00006391 50.0
HFD3_k127_3175269_0 Molydopterin dinucleotide binding domain K07306 - 1.8.5.3 1.386e-239 762.0
HFD3_k127_3175269_1 4Fe-4S dicluster domain K07307 - - 0.000000000000000000000000000000000000000000000000000000000000000000006051 252.0
HFD3_k127_3175269_2 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000001404 215.0
HFD3_k127_3175269_3 PFAM Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000005981 207.0
HFD3_k127_3175269_4 response regulator K07689 - - 0.00000000000000000000000001547 114.0
HFD3_k127_3180218_0 PFAM lipopolysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 320.0
HFD3_k127_3180218_1 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000002232 203.0
HFD3_k127_3182959_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005634 479.0
HFD3_k127_3182959_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000961 199.0
HFD3_k127_3182959_2 lipid binding - - - 0.000000000000000000000000000000000000000000002535 175.0
HFD3_k127_3189436_0 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005261 264.0
HFD3_k127_3189436_1 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001189 256.0
HFD3_k127_3189436_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000006095 93.0
HFD3_k127_3197575_0 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003067 518.0
HFD3_k127_3197575_1 PFAM Amidohydrolase 2 K03392,K07045 - 4.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 378.0
HFD3_k127_3197575_2 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003621 369.0
HFD3_k127_3197575_3 PFAM ABC transporter K16786,K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006206 273.0
HFD3_k127_3197575_4 ATPases associated with a variety of cellular activities K16786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002614 271.0
HFD3_k127_3197575_5 PFAM CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.00000000000000000000000000000000000000000000000000000000000002392 236.0
HFD3_k127_3197575_6 PFAM Cobalt transport protein K16785 - - 0.000000000000000000000000000000000000000000000000000008007 200.0
HFD3_k127_3197575_7 ATPase activity - - - 0.00000000000000000002197 98.0
HFD3_k127_3205927_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 612.0
HFD3_k127_3205927_1 TIGRFAM NRAMP (natural resistance-associated macrophage protein) metal ion transporters - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 479.0
HFD3_k127_3205927_10 holo-[acyl-carrier-protein] synthase activity K00997,K18014 - 2.7.8.7,4.3.1.14 0.00000000000000000000000000009969 124.0
HFD3_k127_3205927_2 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 450.0
HFD3_k127_3205927_3 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 399.0
HFD3_k127_3205927_4 MgtE intracellular N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006072 308.0
HFD3_k127_3205927_5 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003521 281.0
HFD3_k127_3205927_6 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000007367 207.0
HFD3_k127_3205927_7 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000001022 194.0
HFD3_k127_3205927_8 MaoC like domain - - - 0.000000000000000000000000000000000000000000000004328 176.0
HFD3_k127_3205927_9 Putative ABC-transporter type IV - - - 0.00000000000000000000000000000235 124.0
HFD3_k127_3206087_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.694e-221 704.0
HFD3_k127_3206087_1 aminotransferase class I and II K14155 - 4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 497.0
HFD3_k127_3206087_10 glycosyl hydrolase, BNR repeat-containing protein - - - 0.00000000000001571 85.0
HFD3_k127_3206087_11 YcxB-like protein - - - 0.0008115 50.0
HFD3_k127_3206087_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 365.0
HFD3_k127_3206087_3 TIGRFAM phosphate ABC transporter, phosphate-binding protein K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004327 364.0
HFD3_k127_3206087_4 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 317.0
HFD3_k127_3206087_5 Phosphate transport system permease protein PstA K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008589 272.0
HFD3_k127_3206087_6 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000005648 214.0
HFD3_k127_3206087_7 - - - - 0.00000000000000000000000000000002118 142.0
HFD3_k127_3206087_8 TIGRFAM phosphohistidine phosphatase SixA K08296 - - 0.0000000000000000000000000000002461 128.0
HFD3_k127_3206087_9 TIGRFAM phosphoesterase, MJ0936 family K07095 - - 0.0000000000000000000000000001621 116.0
HFD3_k127_3217618_0 PFAM glycosyl transferase, family 51 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 372.0
HFD3_k127_3217618_1 MaoC like domain - - - 0.0000000000000000000000000000000000000000003892 162.0
HFD3_k127_3231749_0 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 486.0
HFD3_k127_3231749_1 glycerophosphodiester transmembrane transport K02026,K17317 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 413.0
HFD3_k127_3231749_2 Binding-protein-dependent transport system inner membrane component K17316 - - 0.0000000000000000000000000000000000000000000000000000000000000587 218.0
HFD3_k127_32349_0 Pfam:KaiC K08482 - - 1.991e-219 697.0
HFD3_k127_32349_1 carbohydrate transport K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002103 547.0
HFD3_k127_32349_2 alcohol dehydrogenase K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004551 409.0
HFD3_k127_32349_3 glycerophosphodiester transmembrane transport K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 394.0
HFD3_k127_32349_4 Binding-protein-dependent transport system inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 325.0
HFD3_k127_32349_5 KaiB K08481 - - 0.0000000000000000000000000000000000000008395 151.0
HFD3_k127_32349_6 KaiB K08481 - - 0.00000000000000000000000000000001136 130.0
HFD3_k127_32349_7 PFAM Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain - - - 0.0000000000000001375 81.0
HFD3_k127_3249039_0 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 2.171e-264 834.0
HFD3_k127_3249039_1 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 2.279e-194 615.0
HFD3_k127_3249039_10 Pyridine nucleotide-disulphide oxidoreductase K03387 - - 0.00000000000000000000000000000000000000000000000000000000000000000003422 242.0
HFD3_k127_3249039_11 PFAM dihydropteroate synthase, DHPS K15023 - 2.1.1.258 0.000000000000000000000000000000000000000000000000003121 194.0
HFD3_k127_3249039_12 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000002548 168.0
HFD3_k127_3249039_13 CoA binding domain K06929 - - 0.000000000000000000000000000000003182 135.0
HFD3_k127_3249039_14 4Fe-4S dicluster domain K05524 - - 0.000000000000000000000000000001645 123.0
HFD3_k127_3249039_15 transcriptional regulator, Rrf2 family - - - 0.0000000000000000000000001346 111.0
HFD3_k127_3249039_16 - - - - 0.00000000000000000005153 100.0
HFD3_k127_3249039_17 CBS domain - - - 0.0000000000000001937 85.0
HFD3_k127_3249039_18 iron-sulfur cluster assembly - - - 0.000000000000008453 78.0
HFD3_k127_3249039_19 - - - - 0.000000000004126 78.0
HFD3_k127_3249039_2 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007789 544.0
HFD3_k127_3249039_20 YoaP-like - - - 0.000001638 59.0
HFD3_k127_3249039_3 Domain of unknown function (DUF4445) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003344 538.0
HFD3_k127_3249039_4 CO dehydrogenase/acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006247 403.0
HFD3_k127_3249039_5 methenyltetrahydrofolate cyclohydrolase activity K00288 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009507,GO:0009536,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019219,GO:0019222,GO:0019238,GO:0019752,GO:0031323,GO:0034641,GO:0042558,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0044030,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046653,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0051186,GO:0055114,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901360,GO:1901564 1.5.1.5,3.5.4.9,6.3.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000434 361.0
HFD3_k127_3249039_6 peptidase U32 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009444 334.0
HFD3_k127_3249039_7 CO dehydrogenase/acetyl-CoA synthase delta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007476 323.0
HFD3_k127_3249039_8 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003583 293.0
HFD3_k127_3249039_9 Sodium/calcium exchanger protein K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001593 271.0
HFD3_k127_3249210_0 phosphatidate phosphatase activity K19302 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000005315 194.0
HFD3_k127_3249210_1 Selenium-dependent molybdenum hydroxylase system protein, YqeB family K07402 - - 0.000000000000000000000000000000000000000000000000005922 185.0
HFD3_k127_3249210_2 OsmC-like protein K04063 - - 0.000000000000000000000000000000000000000000005641 167.0
HFD3_k127_3249210_3 Lipocalin-like domain - - - 0.0000000000000000000000000001389 121.0
HFD3_k127_3254155_0 Trypsin-like serine protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009291 287.0
HFD3_k127_3254155_1 PFAM Bacterial transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004025 299.0
HFD3_k127_3254155_2 Alpha/beta hydrolase family K18053 - 1.13.12.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000007074 264.0
HFD3_k127_3269229_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 3.173e-306 945.0
HFD3_k127_3269229_1 PFAM ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000142 277.0
HFD3_k127_3269229_2 Receptor family ligand binding region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002602 274.0
HFD3_k127_3269229_3 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002572 269.0
HFD3_k127_3269229_4 Branched-chain amino acid transport system / permease component K01998,K11961 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002275 253.0
HFD3_k127_3269229_5 Transcriptional regulator - - - 0.0005623 44.0
HFD3_k127_327212_0 Belongs to the ABC transporter superfamily K02010,K10112 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 327.0
HFD3_k127_327212_1 NAD(P)H-binding K17947 - 5.1.3.25 0.0000000000000000000000000000000000000006677 152.0
HFD3_k127_327212_2 Helix-turn-helix domain, rpiR family - - - 0.00000000000000000000000000000000000002056 155.0
HFD3_k127_3272737_0 transcriptional activator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 573.0
HFD3_k127_3272737_1 PHP domain protein K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 462.0
HFD3_k127_3272737_10 - - - - 0.00009279 54.0
HFD3_k127_3272737_2 Belongs to the ABC transporter superfamily K17240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 379.0
HFD3_k127_3272737_3 PFAM Bacterial extracellular solute-binding K17237 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 362.0
HFD3_k127_3272737_4 transmembrane transport K02025,K05814,K10118,K15771,K17238,K17316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 319.0
HFD3_k127_3272737_5 glycerophosphodiester transmembrane transport K15772,K17239 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000105 287.0
HFD3_k127_3272737_6 PFAM sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003344 286.0
HFD3_k127_3272737_7 phosphatase activity K07025 - - 0.0000000000000000000000000000000000000000004454 166.0
HFD3_k127_3272737_8 Dimerisation domain K21377 - 2.1.1.302 0.000000000000000000000002025 115.0
HFD3_k127_3298693_0 heterodisulfide reductase K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004663 464.0
HFD3_k127_3298693_1 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004705 438.0
HFD3_k127_3298693_2 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 365.0
HFD3_k127_3298693_3 Fumarate hydratase (Fumerase) K01677 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006435 342.0
HFD3_k127_3298693_4 PFAM Methylene-tetrahydrofolate reductase C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 292.0
HFD3_k127_3298693_5 Fumarase C-terminus K01678 - 4.2.1.2 0.000000000000000000000000000000000001497 143.0
HFD3_k127_3298693_6 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000000000000000000019 108.0
HFD3_k127_3298693_7 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.00000000000000000008496 91.0
HFD3_k127_3309090_0 PFAM Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 412.0
HFD3_k127_3309090_1 histidine kinase, dimerisation and phosphoacceptor region K07777 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000002932 273.0
HFD3_k127_3309090_10 kelch-like K10448 GO:0000003,GO:0000151,GO:0000902,GO:0001894,GO:0003006,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0006919,GO:0007275,GO:0007276,GO:0007281,GO:0007283,GO:0007286,GO:0007291,GO:0007349,GO:0007548,GO:0008150,GO:0008152,GO:0008406,GO:0008584,GO:0009566,GO:0009653,GO:0009887,GO:0009893,GO:0009987,GO:0010604,GO:0010941,GO:0010942,GO:0010950,GO:0010952,GO:0016043,GO:0016567,GO:0019222,GO:0019538,GO:0019953,GO:0022412,GO:0022414,GO:0030154,GO:0030162,GO:0030539,GO:0031323,GO:0031325,GO:0031461,GO:0031463,GO:0032268,GO:0032270,GO:0032446,GO:0032501,GO:0032502,GO:0032504,GO:0032989,GO:0032991,GO:0035112,GO:0036211,GO:0042592,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043085,GO:0043170,GO:0043280,GO:0043281,GO:0043412,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0044703,GO:0045137,GO:0045862,GO:0046546,GO:0046661,GO:0048232,GO:0048468,GO:0048513,GO:0048515,GO:0048518,GO:0048522,GO:0048608,GO:0048609,GO:0048646,GO:0048731,GO:0048806,GO:0048808,GO:0048856,GO:0048869,GO:0048871,GO:0048872,GO:0048873,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051336,GO:0051345,GO:0051704,GO:0052547,GO:0052548,GO:0060249,GO:0060255,GO:0061458,GO:0065007,GO:0065008,GO:0065009,GO:0070647,GO:0071704,GO:0071840,GO:0080090,GO:0090598,GO:1901564,GO:1902494,GO:1990234,GO:2000116,GO:2001056 - 0.0001774 52.0
HFD3_k127_3309090_2 Electron transfer flavoprotein domain K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002132 262.0
HFD3_k127_3309090_3 PFAM regulatory protein LuxR - - - 0.000000000000000000000000000000000000000000000000000000000000000000002021 244.0
HFD3_k127_3309090_4 Signal transduction histidine kinase K07777 - 2.7.13.3 0.0000000000000000000000000000000000000001151 158.0
HFD3_k127_3309090_5 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.00000000000000000006758 93.0
HFD3_k127_3309090_7 PFAM TadE family protein - - - 0.00000000104 65.0
HFD3_k127_3309090_8 TadE-like protein - - - 0.000000002243 65.0
HFD3_k127_3309090_9 PFAM TadE family protein - - - 0.00001104 57.0
HFD3_k127_331109_0 peptidase dimerisation domain protein K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003635 269.0
HFD3_k127_331109_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000004219 218.0
HFD3_k127_3320153_0 Belongs to the IlvD Edd family K22396 - 4.2.1.82 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 578.0
HFD3_k127_3320153_1 serine threonine protein phosphatase K20074 - 3.1.3.16 0.0000000002226 73.0
HFD3_k127_3323335_0 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 374.0
HFD3_k127_3323335_1 ATPases associated with a variety of cellular activities K05833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008791 291.0
HFD3_k127_3323335_2 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000168 280.0
HFD3_k127_3323335_3 PFAM Branched-chain amino acid transport system permease component K05832 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002405 277.0
HFD3_k127_3323335_4 PFAM ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001755 260.0
HFD3_k127_3323335_5 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004162 254.0
HFD3_k127_3323335_6 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.00000000000000000000000000000000000000000000000000000007223 204.0
HFD3_k127_3323335_7 Aldolase/RraA K10218 - 4.1.3.17 0.000000000000000000000000000000000000000000000196 175.0
HFD3_k127_3323335_8 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.00000000000000000000000000000000000000001082 166.0
HFD3_k127_3323335_9 AraC-like ligand binding domain - - - 0.000000003744 63.0
HFD3_k127_332822_0 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 454.0
HFD3_k127_332822_1 Immune inhibitor A peptidase M6 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 413.0
HFD3_k127_332822_2 Multicopper oxidase K00368 - 1.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006719 293.0
HFD3_k127_332822_3 PFAM Cyclic nucleotide-binding K10914 - - 0.00000000000000000000000000000000000000000000000000009704 193.0
HFD3_k127_332822_4 molybdenum cofactor K03638,K03831 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000002536 190.0
HFD3_k127_332822_5 Peptidase family S58 K01266 - 3.4.11.19 0.0000000000000000000000000000005019 126.0
HFD3_k127_332822_6 Auxin binding protein - - - 0.0000000241 61.0
HFD3_k127_3333142_0 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000279 117.0
HFD3_k127_3333142_1 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00006489 55.0
HFD3_k127_3334271_0 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 297.0
HFD3_k127_3334271_1 Bacterial regulatory helix-turn-helix protein, lysR family K21703 - - 0.0000000000000000000000000001502 120.0
HFD3_k127_3361084_0 ABC-type dipeptide transport system periplasmic component K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 511.0
HFD3_k127_3361084_1 nitrogen compound transport K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 385.0
HFD3_k127_3361084_2 SPTR D1CI93 Phophonate C-P lyase system transcriptional regulator PhnF, GntR family K03710 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003801 265.0
HFD3_k127_3361084_3 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00007035 49.0
HFD3_k127_3361202_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 555.0
HFD3_k127_3361202_1 the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms K00958 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 539.0
HFD3_k127_3361202_10 - - - - 0.0000000000000000000000003392 121.0
HFD3_k127_3361202_11 Pfam:DUF385 - - - 0.000000000000000002704 88.0
HFD3_k127_3361202_12 Aldo/keto reductase family - - - 0.00000000004918 65.0
HFD3_k127_3361202_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004503 338.0
HFD3_k127_3361202_3 Catalyzes the synthesis of activated sulfate K00390,K00860 - 1.8.4.10,1.8.4.8,2.7.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000004966 264.0
HFD3_k127_3361202_4 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001275 263.0
HFD3_k127_3361202_5 Hexapeptide repeat of succinyl-transferase - - - 0.000000000000000000000000000000000000000000000000000000002867 206.0
HFD3_k127_3361202_6 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000006141 156.0
HFD3_k127_3361202_7 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000002005 149.0
HFD3_k127_3361202_9 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000002466 114.0
HFD3_k127_3376048_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000001163 89.0
HFD3_k127_3376048_1 - - - - 0.00000003288 61.0
HFD3_k127_3376048_2 helix_turn_helix, Lux Regulon - - - 0.0000004132 62.0
HFD3_k127_3382776_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005574 574.0
HFD3_k127_3382776_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 481.0
HFD3_k127_3382776_2 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000005067 136.0
HFD3_k127_3382776_3 xanthine dehydrogenase activity K03519 - 1.2.5.3 0.00001476 48.0
HFD3_k127_3383725_0 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 377.0
HFD3_k127_3383725_1 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002805 348.0
HFD3_k127_3383725_2 hmm pf02371 K07486 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004879 316.0
HFD3_k127_3383725_3 FAD dependent oxidoreductase - - - 0.00000000000000000000000002864 108.0
HFD3_k127_3383902_0 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 447.0
HFD3_k127_3383902_1 Homocysteine S-methyltransferase K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000005547 250.0
HFD3_k127_3389016_0 Natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 404.0
HFD3_k127_3389016_1 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 361.0
HFD3_k127_3389016_10 Predicted membrane protein (DUF2085) - - - 0.00000000000000000000000000000004699 134.0
HFD3_k127_3389016_11 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749 - - 0.000000000000000000000000003918 116.0
HFD3_k127_3389016_12 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000009332 102.0
HFD3_k127_3389016_13 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000001312 95.0
HFD3_k127_3389016_2 WD40 domain protein beta Propeller K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003895 307.0
HFD3_k127_3389016_3 AAA domain, putative AbiEii toxin, Type IV TA system K02006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001916 282.0
HFD3_k127_3389016_4 Melibiase K07407 - 3.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000001968 261.0
HFD3_k127_3389016_5 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002091 245.0
HFD3_k127_3389016_6 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.000000000000000000000000000000000000000000000000000000000000001167 229.0
HFD3_k127_3389016_7 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000000000000002136 166.0
HFD3_k127_3389016_8 Predicted membrane protein (DUF2085) - - - 0.000000000000000000000000000000000000007382 155.0
HFD3_k127_3389016_9 Ferric uptake regulator family K03711 - - 0.0000000000000000000000000000000000007177 144.0
HFD3_k127_3392076_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006079 542.0
HFD3_k127_3392076_1 helix_turn_helix, Lux Regulon K02479 - - 0.000000000000000002873 85.0
HFD3_k127_3392076_2 ABC transporter K02003 - - 0.0000000000000002287 80.0
HFD3_k127_3399386_0 Coenzyme A transferase K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 426.0
HFD3_k127_3399386_1 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 382.0
HFD3_k127_3399386_2 PFAM phenylacetic acid catabolic family protein K02611 - 1.14.13.149 0.000000000000000000000000000000000000000000000005313 180.0
HFD3_k127_3399386_3 - - - - 0.00000000000000000000001465 108.0
HFD3_k127_3399386_5 - - - - 0.000000002898 66.0
HFD3_k127_3400873_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 417.0
HFD3_k127_3400873_1 Bacterial transcriptional activator domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 400.0
HFD3_k127_3400873_2 Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000002787 76.0
HFD3_k127_3404363_0 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003969 497.0
HFD3_k127_3404363_1 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007324 449.0
HFD3_k127_3404363_10 PFAM Cyclic nucleotide-binding - - - 0.0000000000000969 86.0
HFD3_k127_3404363_11 AAA ATPase domain - - - 0.000000000807 66.0
HFD3_k127_3404363_12 Peptidase family M28 - - - 0.000002732 59.0
HFD3_k127_3404363_2 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009421 417.0
HFD3_k127_3404363_3 PFAM ABC transporter related K16786,K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 349.0
HFD3_k127_3404363_4 transmembrane transport K02035,K15580 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006810,GO:0006811,GO:0006820,GO:0006857,GO:0006869,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010876,GO:0015711,GO:0015718,GO:0015721,GO:0015833,GO:0015849,GO:0015850,GO:0030288,GO:0030313,GO:0031975,GO:0033036,GO:0033218,GO:0042277,GO:0042597,GO:0042886,GO:0042939,GO:0044464,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0061077,GO:0071702,GO:0071705,GO:1900750 - 0.00000000000000000000000000000000000000000000000000000000000000000000004782 261.0
HFD3_k127_3404363_5 PFAM NUDIX hydrolase K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000001008 192.0
HFD3_k127_3404363_6 family 25 K01185,K07273 GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.2.1.17 0.0000000000000000000000000000006713 133.0
HFD3_k127_3404363_7 PFAM Acetyltransferase (GNAT) family - - - 0.000000000000000000000002891 109.0
HFD3_k127_3404363_8 AAA ATPase domain - - - 0.0000000000000000001785 103.0
HFD3_k127_3404363_9 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000008536 85.0
HFD3_k127_3407850_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 559.0
HFD3_k127_3407850_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000000000000000000000000000000000000004704 220.0
HFD3_k127_3429781_0 NAD(P)H-binding K17947 - 5.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003685 412.0
HFD3_k127_3429781_1 CoA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009526 382.0
HFD3_k127_3429781_2 PFAM GHMP kinase K07031 - 2.7.1.168 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000352 314.0
HFD3_k127_3429781_3 PFAM sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002742 293.0
HFD3_k127_3429781_4 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001487 253.0
HFD3_k127_3429781_5 Bacterial sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001152 241.0
HFD3_k127_3429781_6 TIGRFAM histidinol-phosphate phosphatase family protein K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000006076 171.0
HFD3_k127_3429781_7 -O-antigen K13009,K18814 - - 0.00000000000000000000000000000007052 141.0
HFD3_k127_3429781_8 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000003204 121.0
HFD3_k127_3429781_9 COG0438 Glycosyltransferase - - - 0.00000000006104 66.0
HFD3_k127_3438194_0 Melibiase K07407 - 3.2.1.22 0.0000000000000000000000000000000000000000000000000000008104 207.0
HFD3_k127_3438194_1 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.00000000000000000000000000000000000000000000000000001286 195.0
HFD3_k127_3441347_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 2.394e-194 619.0
HFD3_k127_3441347_1 Haloacid dehalogenase-like hydrolase K02566 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009125,GO:0009129,GO:0009131,GO:0009158,GO:0009161,GO:0009164,GO:0009166,GO:0009173,GO:0009175,GO:0009218,GO:0009222,GO:0009259,GO:0009261,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046050,GO:0046131,GO:0046133,GO:0046135,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 350.0
HFD3_k127_3441347_2 - - - - 0.0000000000000000000000000000000000000000000000000008403 190.0
HFD3_k127_3441347_3 Lytic murein transglycosylase K08307 - - 0.00000122 57.0
HFD3_k127_3441347_4 Tetratricopeptide repeat - - - 0.000002669 56.0
HFD3_k127_3459762_0 Creatinase/Prolidase N-terminal domain K01271,K15783 - 3.4.13.9,3.5.4.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000679 593.0
HFD3_k127_3459762_1 Psort location Cytoplasmic, score - - - 0.00000000000000000000000001244 119.0
HFD3_k127_3459762_2 PFAM amidohydrolase K01464 - 3.5.2.2 0.000003394 49.0
HFD3_k127_3472709_0 3-isopropylmalate dehydratase activity K01681,K01703,K01704,K17749 - 4.2.1.3,4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003378 597.0
HFD3_k127_3472709_1 dipeptide transport K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 440.0
HFD3_k127_3472709_2 Belongs to the ABC transporter superfamily K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 418.0
HFD3_k127_3472709_3 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 404.0
HFD3_k127_3472709_4 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009996 270.0
HFD3_k127_3472709_5 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034,K15582 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001569 249.0
HFD3_k127_3472709_6 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000244 137.0
HFD3_k127_34735_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 9.357e-199 623.0
HFD3_k127_34735_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 383.0
HFD3_k127_34735_10 PFAM Prenyltransferase squalene oxidase - - - 0.00000000000000000001422 100.0
HFD3_k127_34735_11 DNA-binding transcription factor activity K03892 - - 0.000000000005857 70.0
HFD3_k127_34735_2 Aspartate carbamoyltransferase K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004324 325.0
HFD3_k127_34735_3 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000308 301.0
HFD3_k127_34735_4 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000104 269.0
HFD3_k127_34735_5 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000162 256.0
HFD3_k127_34735_6 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000008661 243.0
HFD3_k127_34735_7 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( K02823 - - 0.0000000000000000000000000000000000000000000000000000000000006596 219.0
HFD3_k127_34735_8 Belongs to the OMP decarboxylase family. Type 2 subfamily K00762,K01591,K13421 GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10,4.1.1.23 0.000000000000000000000000000000000000000000000000000000000128 209.0
HFD3_k127_34735_9 Kdo2-lipid A biosynthetic process K02517,K22311 - 2.3.1.241,2.3.1.265 0.0000000000000000000000000000000000000000000000004446 190.0
HFD3_k127_3481841_0 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 459.0
HFD3_k127_3481841_1 purine nucleotide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001482 259.0
HFD3_k127_3481841_2 protein homooligomerization - - - 0.000000000000000000000000000000000000000000000000004169 188.0
HFD3_k127_3502688_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 619.0
HFD3_k127_3502688_1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 550.0
HFD3_k127_3502688_2 ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005187 369.0
HFD3_k127_3502688_3 enzyme of poly-gamma-glutamate biosynthesis (Capsule formation) K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000000001207 239.0
HFD3_k127_3507515_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 8.891e-266 827.0
HFD3_k127_3507515_1 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008646 415.0
HFD3_k127_3507515_2 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000000000000000000002222 153.0
HFD3_k127_3507515_3 PFAM OsmC family protein K07397 - - 0.00000000000000000000000000000000000007517 146.0
HFD3_k127_3507515_4 nitrate reductase activity - - - 0.0000000000000000000000000000000006802 138.0
HFD3_k127_3507515_5 Nitrate reductase delta subunit - - - 0.0000000000000000000000000006544 127.0
HFD3_k127_3507515_6 Transcriptional regulator, arsR family - - - 0.000000000000000000000003274 105.0
HFD3_k127_3507515_7 Belongs to the sulfur carrier protein TusA family - - - 0.00000000000000003682 86.0
HFD3_k127_351569_0 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 350.0
HFD3_k127_351569_1 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004522 317.0
HFD3_k127_351569_2 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001554 286.0
HFD3_k127_351569_3 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005729 258.0
HFD3_k127_351569_4 ABC transporter substrate-binding protein K02035 - - 0.00000000000000000000000000000000000000000000001635 191.0
HFD3_k127_351569_5 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000003245 188.0
HFD3_k127_352051_0 IMP dehydrogenase activity K03406,K15371 - 1.4.1.2 1.58e-208 667.0
HFD3_k127_352051_1 Psort location Cytoplasmic, score K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000005759 174.0
HFD3_k127_352051_2 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000000000001143 171.0
HFD3_k127_3559853_0 TIGRFAM riboflavin biosynthesis protein RibF K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002954 278.0
HFD3_k127_3559853_1 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000004983 237.0
HFD3_k127_3559853_2 domain protein K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000001115 207.0
HFD3_k127_3559853_3 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.00000000000000000000000000000000000000000006735 164.0
HFD3_k127_3559853_4 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000004263 100.0
HFD3_k127_3559853_5 Archease protein family (MTH1598/TM1083) - - - 0.0007745 42.0
HFD3_k127_3562270_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K07218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001279 250.0
HFD3_k127_3562270_1 - K19341 - - 0.000000000000000000000000000000000000000000000000000000000000000000001294 247.0
HFD3_k127_3562270_2 NosL K19342 - - 0.000000000000000000000000000001104 126.0
HFD3_k127_3562270_3 Cytochrome c K03611 - - 0.00000000000000000000000000000144 126.0
HFD3_k127_3562270_4 Cupin domain - - - 0.0000000000171 70.0
HFD3_k127_3562270_5 - - - - 0.0001442 49.0
HFD3_k127_3575420_0 Allophanate hydrolase subunit 2 K06350 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006922 444.0
HFD3_k127_3575420_1 PrpF protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001157 231.0
HFD3_k127_3575420_2 Belongs to the UPF0271 (lamB) family K07160 - - 0.000000000000000000001015 96.0
HFD3_k127_3575420_3 Ribosomal protein S27a - - - 0.0002481 49.0
HFD3_k127_3593121_0 glycoside hydrolase 15-related K01178 - 3.2.1.3 0.0 1504.0
HFD3_k127_36155_0 PFAM ABC transporter transmembrane region K11085 - - 7.369e-214 682.0
HFD3_k127_36155_1 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004556 368.0
HFD3_k127_36155_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005381 367.0
HFD3_k127_36155_3 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000006556 136.0
HFD3_k127_3618025_0 Peptidase S53 K08677 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 344.0
HFD3_k127_3618025_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.000000000000000000000000000000000000000000000000000000001127 206.0
HFD3_k127_3619574_0 Protoporphyrinogen oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 597.0
HFD3_k127_3619574_1 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000834 320.0
HFD3_k127_3619574_2 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000003237 167.0
HFD3_k127_3619574_3 Serine threonine protein kinase K12132 - 2.7.11.1 0.000006622 55.0
HFD3_k127_3619574_4 - - - - 0.00001179 52.0
HFD3_k127_3634023_0 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 625.0
HFD3_k127_3634023_1 enterobactin catabolic process - - - 0.000000000000003857 81.0
HFD3_k127_3675646_0 metalloendopeptidase activity K08602 - - 5.083e-202 640.0
HFD3_k127_3675646_1 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001941 261.0
HFD3_k127_3675646_2 histidine kinase, dimerisation and phosphoacceptor region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001555 265.0
HFD3_k127_3675646_3 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.0000000000000000000000000000000000000000000000000000000001141 216.0
HFD3_k127_369452_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 549.0
HFD3_k127_369452_1 PFAM RNA binding S1 domain protein K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008489 270.0
HFD3_k127_369452_2 lactoylglutathione lyase activity K01239 - 3.2.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000001221 250.0
HFD3_k127_369452_3 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000002094 192.0
HFD3_k127_369452_4 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.00000000000000000000000000000001802 127.0
HFD3_k127_369452_5 PFAM cyclase family protein K07130 - 3.5.1.9 0.000000000000000000000000005088 112.0
HFD3_k127_369452_6 transposition K07497 - - 0.0000000000000001046 83.0
HFD3_k127_3702234_0 Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005645 405.0
HFD3_k127_3702234_1 Flavin containing amine oxidoreductase - - - 0.0000001001 65.0
HFD3_k127_3702234_2 PFAM Metallo-beta-lactamase superfamily K02238 - - 0.0002035 46.0
HFD3_k127_3741208_0 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 469.0
HFD3_k127_3741208_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 410.0
HFD3_k127_3741208_2 nitrogen compound transport K00759,K02033 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 373.0
HFD3_k127_3741208_3 Belongs to the ABC transporter superfamily K02031,K02032,K15583 - - 0.00000000001268 65.0
HFD3_k127_3751453_0 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000001908 136.0
HFD3_k127_3751453_1 LysM domain - - - 0.00000000000000000000000008481 121.0
HFD3_k127_3751453_2 - - - - 0.000000000006417 70.0
HFD3_k127_3765408_0 COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component K09014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 542.0
HFD3_k127_3765408_1 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 456.0
HFD3_k127_3765408_2 Uncharacterized protein family (UPF0051) K09015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 403.0
HFD3_k127_3765408_3 NifU-like N terminal domain K04488 - - 0.00000000000000000000000000000000000000008668 155.0
HFD3_k127_3765408_4 4Fe-4S dicluster domain K05524 - - 0.0000000000000000000000000000003682 128.0
HFD3_k127_3786030_0 Xaa-Pro aminopeptidase K01271 - 3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000005647 234.0
HFD3_k127_3786030_1 FCD domain - - - 0.00000000000000000000000000000000002615 143.0
HFD3_k127_3798686_0 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 313.0
HFD3_k127_3798686_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007343 277.0
HFD3_k127_3801791_0 CoA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 367.0
HFD3_k127_3801791_1 Membrane - - - 0.0000000000000000000000000000000000005237 160.0
HFD3_k127_3801791_2 glycosyl transferase family 2 K07011 - - 0.000000001683 61.0
HFD3_k127_380898_0 Type II/IV secretion system protein K02283 - - 3.295e-196 621.0
HFD3_k127_380898_1 PFAM response regulator receiver K02282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 376.0
HFD3_k127_380898_2 PFAM type II secretion system protein K12511 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001194 267.0
HFD3_k127_380898_3 Type II secretion system (T2SS), protein F K12510 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001637 267.0
HFD3_k127_380898_4 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000000285 105.0
HFD3_k127_380898_5 Pilus assembly protein CpaB K02279 - - 0.0000000000004361 79.0
HFD3_k127_3882402_0 Phosphofructokinase K21071 - 2.7.1.11,2.7.1.90 5.678e-202 634.0
HFD3_k127_3882402_1 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 453.0
HFD3_k127_3882402_2 CBD_II K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 312.0
HFD3_k127_3882402_3 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000001542 147.0
HFD3_k127_3882402_4 - - - - 0.00000001412 60.0
HFD3_k127_3882402_5 SMART RNA-processing protein HAT helix repeating-containing protein - - - 0.0004983 49.0
HFD3_k127_3887786_0 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003433 281.0
HFD3_k127_3887786_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001428 262.0
HFD3_k127_3887786_2 Integrase core domain - - - 0.000000000000000000000000006018 115.0
HFD3_k127_3887786_3 IstB-like ATP binding protein - - - 0.0000000000000000000000001553 110.0
HFD3_k127_3891626_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 4.257e-278 864.0
HFD3_k127_3891626_1 tRNA synthetases class I (C) catalytic domain K01883,K15526 GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 6.1.1.16,6.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006396 421.0
HFD3_k127_3891626_2 SelR domain K07304,K07305,K12267 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006807,GO:0008113,GO:0008150,GO:0008152,GO:0008270,GO:0009405,GO:0009987,GO:0016491,GO:0016667,GO:0016671,GO:0019538,GO:0030091,GO:0033743,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051704,GO:0055114,GO:0071704,GO:1901564 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000002064 211.0
HFD3_k127_3893212_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 585.0
HFD3_k127_3893212_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000002399 217.0
HFD3_k127_3893212_2 electron transfer flavoprotein, alpha subunit K03522,K22432 - 1.3.1.108 0.0000000000000000000000000000000000000000000000000000000003021 209.0
HFD3_k127_3893212_3 Multidrug resistance protein MdtG K08161 GO:0006810,GO:0006855,GO:0008150,GO:0015893,GO:0042221,GO:0042493,GO:0050896,GO:0051179,GO:0051234,GO:0055085 - 0.000000000000000000000000000001089 138.0
HFD3_k127_3893212_4 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000006414 125.0
HFD3_k127_3900837_0 COGs COG0318 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K00666,K01897 - 6.2.1.3 1.653e-213 672.0
HFD3_k127_3913466_0 thiamine transport K02011 - - 9.271e-243 775.0
HFD3_k127_3913466_1 Malate synthase K01638 - 2.3.3.9 1.299e-234 745.0
HFD3_k127_3913466_10 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009812 309.0
HFD3_k127_3913466_11 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K02052 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 293.0
HFD3_k127_3913466_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001823 251.0
HFD3_k127_3913466_13 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004657 252.0
HFD3_k127_3913466_14 PFAM Xylose isomerase domain protein TIM barrel K06606 - 5.3.99.11 0.000000000000000000000000000000000000000000000000000000000002103 220.0
HFD3_k127_3913466_2 Creatinine amidohydrolase K01470,K22232 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009668 497.0
HFD3_k127_3913466_3 Catalyzes the NAD(P)( )-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD( ) and NADP( ) as electron acceptor. Is involved in the degradation of glucose through a - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004902 483.0
HFD3_k127_3913466_4 Dynamin family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 466.0
HFD3_k127_3913466_5 extracellular solute-binding protein, family 1 K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 438.0
HFD3_k127_3913466_6 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K02052 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003528 403.0
HFD3_k127_3913466_7 ABC transporter permease K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 400.0
HFD3_k127_3913466_8 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 341.0
HFD3_k127_3913466_9 helix_turn _helix lactose operon repressor K05499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 338.0
HFD3_k127_3928109_0 PFAM glycosyl transferase, family 51 - - - 1.456e-227 737.0
HFD3_k127_3928109_1 MOFRL family K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009346 474.0
HFD3_k127_3928109_2 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000006028 198.0
HFD3_k127_3928109_3 - - - - 0.000000000000000000000000000007352 128.0
HFD3_k127_3932416_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 5.049e-258 819.0
HFD3_k127_3932416_1 transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007597 536.0
HFD3_k127_3932416_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000003254 254.0
HFD3_k127_3932416_3 - - - - 0.000000000000000000000000000000000000000000000001741 179.0
HFD3_k127_3932416_4 Ig-like domain from next to BRCA1 gene - - - 0.000000000000000000000868 110.0
HFD3_k127_3932416_5 PFAM Uncharacterised BCR, COG1937 K21600 - - 0.0000000000004221 73.0
HFD3_k127_3932416_6 Heavy-metal-associated domain - - - 0.0008316 44.0
HFD3_k127_3933196_0 leucine import across plasma membrane K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 473.0
HFD3_k127_3933196_1 Periplasmic binding protein domain K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 469.0
HFD3_k127_3933196_10 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000004248 119.0
HFD3_k127_3933196_11 COGs COG0318 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K00666 - - 0.00000000000000000000001832 100.0
HFD3_k127_3933196_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 405.0
HFD3_k127_3933196_3 PFAM ABC transporter related K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 343.0
HFD3_k127_3933196_4 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005086 349.0
HFD3_k127_3933196_5 PFAM ABC transporter related K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004364 335.0
HFD3_k127_3933196_6 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000009517 267.0
HFD3_k127_3933196_7 N-terminal half of MaoC dehydratase K17865 - 4.2.1.55 0.00000000000000000000000000000000000000000002506 164.0
HFD3_k127_3933196_8 dehydratase - - - 0.00000000000000000000000000000000009652 139.0
HFD3_k127_3933196_9 dehydratase K17865,K19659 - 4.2.1.119,4.2.1.55 0.000000000000000000000000000000001597 134.0
HFD3_k127_3935086_0 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 289.0
HFD3_k127_3935086_1 Uncharacterized membrane protein (DUF2298) - - - 0.00000000000000000000000000000000000000000000000000000000000000002111 241.0
HFD3_k127_3935086_2 PFAM glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000004984 214.0
HFD3_k127_393509_0 CHAT domain - - - 2.351e-206 664.0
HFD3_k127_393509_1 WD-40 repeat-containing protein K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000001273 233.0
HFD3_k127_393509_2 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000004155 213.0
HFD3_k127_393509_3 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000007661 179.0
HFD3_k127_393509_4 peptidase C60 sortase A and B K07284 - 3.4.22.70 0.0000000000000000000000001672 117.0
HFD3_k127_3938457_0 TIGRFAM serine O-acetyltransferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 311.0
HFD3_k127_3938457_1 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000003907 188.0
HFD3_k127_3938457_2 NMT1-like family K02051 - - 0.00000000000192 78.0
HFD3_k127_3943006_0 Fumarylacetoacetate (FAA) hydrolase family K01826 - 5.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000216 282.0
HFD3_k127_3943006_1 PFAM glutamine amidotransferase class-I K07010 - - 0.0000000000000000000000000000000000000000000000000000000000003585 218.0
HFD3_k127_3943006_2 Peptidase dimerisation domain K01295 - 3.4.17.11 0.000000000000000000000000000000000000000000000001959 180.0
HFD3_k127_3943006_3 Mechanosensitive ion channel K03442 - - 0.00000000000000000331 94.0
HFD3_k127_3943006_4 Tetratricopeptide repeat - - - 0.000000003859 69.0
HFD3_k127_3943006_6 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0008386 48.0
HFD3_k127_394569_0 PFAM Cytochrome c assembly protein K02198 - - 2.221e-202 651.0
HFD3_k127_394569_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 369.0
HFD3_k127_394569_10 denitrification pathway K02569,K03532,K15876 - - 0.000006553 55.0
HFD3_k127_394569_11 - - - - 0.00002835 52.0
HFD3_k127_394569_2 lipoprotein transporter activity K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 310.0
HFD3_k127_394569_3 uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005451 282.0
HFD3_k127_394569_4 Cytochrome C assembly protein K02195 GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016021,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0031224,GO:0031226,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044425,GO:0044459,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 - 0.000000000000000000000000000000000000000000000000000000000000000000007721 244.0
HFD3_k127_394569_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000003884 114.0
HFD3_k127_394569_6 Biotin-lipoyl like K02005 - - 0.0000000000000000000000006272 119.0
HFD3_k127_394569_7 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000001378 106.0
HFD3_k127_394569_8 zinc-ribbon domain - - - 0.00000005752 61.0
HFD3_k127_394569_9 - - - - 0.0000002568 61.0
HFD3_k127_3955791_0 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001473 245.0
HFD3_k127_3955791_1 histidine kinase dimerisation and phosphoacceptor region K03406,K07673,K07675 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000105 215.0
HFD3_k127_3955791_2 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000001414 132.0
HFD3_k127_3955791_3 Shikimate kinase - - - 0.0000000000000000000000000000001802 126.0
HFD3_k127_3955791_4 AAA domain - - - 0.00000000000000844 76.0
HFD3_k127_3955791_5 helix_turn_helix, Lux Regulon - - - 0.000000006864 63.0
HFD3_k127_3955791_6 MoeA domain protein domain I and II K00963,K03750 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0071944,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.10.1.1,2.7.7.9 0.000005206 49.0
HFD3_k127_3955791_7 GHKL domain - - - 0.0003872 54.0
HFD3_k127_3957757_0 Thymidylate synthase K00560 - 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000001018 254.0
HFD3_k127_3957757_1 chromosome segregation K03497 - - 0.0000000000000000000000000000000000000002199 162.0
HFD3_k127_3966473_0 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 2.5e-203 648.0
HFD3_k127_3966473_1 ABC transporter substrate-binding protein PnrA-like K02058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005552 346.0
HFD3_k127_3966473_2 Catalyzes the transformation of hydroxyatrazine to N-isopropylammelide and ethylamine in the atrazine degradation pathway K18456 - 3.5.4.32 0.000000000000000000000000000000000000000004885 157.0
HFD3_k127_3966473_3 DNA polymerase beta domain protein region K07075 - - 0.00000000000000009077 83.0
HFD3_k127_3969509_0 Glucose dehydrogenase C-terminus K00008,K00060 - 1.1.1.103,1.1.1.14 2.899e-205 641.0
HFD3_k127_3969509_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005454 579.0
HFD3_k127_3969509_2 helicase activity K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 471.0
HFD3_k127_3969509_3 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 344.0
HFD3_k127_3969509_4 3'-5' exonuclease activity K03546,K03547 - - 0.00000000000000000000000000000000000000000000000000000000000013 227.0
HFD3_k127_3969509_5 Serine aminopeptidase, S33 K03928 - 3.1.1.1 0.00000000000000000000000000000000000000000000005786 179.0
HFD3_k127_3969509_6 ACT domain K09707 - - 0.00000000000000000000000000000000000000002076 155.0
HFD3_k127_3969509_7 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000001324 144.0
HFD3_k127_3969509_8 Winged helix DNA-binding domain - - - 0.00000000000000000000000000158 114.0
HFD3_k127_3969509_9 - - - - 0.00000000000000000000004889 104.0
HFD3_k127_39710_0 AAA ATPase domain - - - 5.337e-224 737.0
HFD3_k127_39710_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009013 315.0
HFD3_k127_39710_2 - - - - 0.0000000000000000000000000000008941 130.0
HFD3_k127_39710_3 Stage II sporulation protein E K05518 - 3.1.3.3 0.00000000000000000002463 92.0
HFD3_k127_39710_4 - - - - 0.000000000002134 75.0
HFD3_k127_39710_5 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0001674 47.0
HFD3_k127_3972030_0 Elongation factor G C-terminus K06207 GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840 - 4.875e-275 862.0
HFD3_k127_3972030_1 Removes 5-oxoproline from various penultimate amino acid residues except L-proline K01304 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:1901564 3.4.19.3 0.00000000000000000003606 92.0
HFD3_k127_3972030_2 PFAM Vitamin K epoxide reductase - - - 0.0000205 50.0
HFD3_k127_3983316_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000006342 197.0
HFD3_k127_3983316_1 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000004836 182.0
HFD3_k127_3983316_2 histidine kinase, dimerisation and phosphoacceptor region - - - 0.00000000000000000000000000000000000000077 166.0
HFD3_k127_3997200_0 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 492.0
HFD3_k127_3997200_1 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005192 349.0
HFD3_k127_3997200_2 PFAM ThiamineS - - - 0.000004217 51.0
HFD3_k127_3997442_0 Belongs to the ParA family K03609 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004278 365.0
HFD3_k127_3997442_1 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008613 297.0
HFD3_k127_3997442_2 PFAM penicillin-binding protein transpeptidase K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000002551 185.0
HFD3_k127_3997442_3 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization K03610 - - 0.00000000000000000000000000000000000000000008149 168.0
HFD3_k127_3997442_4 23S rRNA-intervening sequence protein - - - 0.00000000000000000000002825 104.0
HFD3_k127_3997442_5 Amidohydrolase family - - - 0.00000000000000000021 93.0
HFD3_k127_3997442_6 Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell K03608 - - 0.00000000000000006792 84.0
HFD3_k127_4004618_0 BadF BadG BcrA BcrD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005075 445.0
HFD3_k127_4004618_1 Peptidase family M20/M25/M40 K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 441.0
HFD3_k127_4004618_2 PFAM CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.000000000000000000000000000000000000000000000792 170.0
HFD3_k127_4010497_0 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004111 579.0
HFD3_k127_4010497_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 535.0
HFD3_k127_4010497_2 protein histidine kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 361.0
HFD3_k127_4010497_3 Two component transcriptional regulator, winged helix family K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 331.0
HFD3_k127_4010497_4 Hsp70 protein K04046 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005131 328.0
HFD3_k127_4010497_5 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000234 272.0
HFD3_k127_4010497_6 Ferritin-like domain K03594 - 1.16.3.1 0.00000000000000000000000000000000000000000000000000000000000000004862 226.0
HFD3_k127_4010497_7 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000009789 161.0
HFD3_k127_4010497_8 Hsp20/alpha crystallin family - - - 0.000000000000000000000000009675 115.0
HFD3_k127_4010497_9 LysM domain K08307,K21471 - - 0.00000009611 60.0
HFD3_k127_4015077_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K13378 - 1.6.5.3 2.091e-240 750.0
HFD3_k127_4015077_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008387 271.0
HFD3_k127_4017026_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006397 393.0
HFD3_k127_4017026_1 PFAM Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006433 381.0
HFD3_k127_4017026_2 Lycopene cyclase protein K06443 - 5.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000002229 231.0
HFD3_k127_4017026_3 Protein of unknown function (DUF3224) - - - 0.00000000003495 65.0
HFD3_k127_4031782_0 Belongs to the glutamate synthase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 437.0
HFD3_k127_4031782_1 His Kinase A (phosphoacceptor) domain K02484,K07653,K07654,K11617 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005515,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009966,GO:0009968,GO:0009987,GO:0010646,GO:0010648,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023051,GO:0023052,GO:0023057,GO:0035556,GO:0036211,GO:0042802,GO:0042803,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046983,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070297,GO:0070298,GO:0071704,GO:0140096,GO:1901564,GO:1902531,GO:1902532 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000004025 261.0
HFD3_k127_4031782_2 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000000000000000000000000004714 186.0
HFD3_k127_4031782_3 Coenzyme F420 hydrogenase dehydrogenase, beta subunit K00441 - 1.12.98.1 0.00000000000000000000000000000000000003831 158.0
HFD3_k127_4031782_4 Glutamate synthase - - - 0.0000000000000000000000000000001883 134.0
HFD3_k127_4031782_5 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.000000000005569 68.0
HFD3_k127_4035608_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 372.0
HFD3_k127_4035608_1 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009217 315.0
HFD3_k127_4035608_2 Putative esterase - - - 0.000000000000000000000000000000000000000002264 159.0
HFD3_k127_4035608_3 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000002953 123.0
HFD3_k127_4038030_0 SAICAR synthetase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 449.0
HFD3_k127_4038030_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 309.0
HFD3_k127_4038030_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003904 308.0
HFD3_k127_4038030_3 phosphoribosylaminoimidazole carboxylase activity K01923 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009719,GO:0009725,GO:0009733,GO:0009987,GO:0010033,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000002 184.0
HFD3_k127_4038030_4 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000007069 141.0
HFD3_k127_4038095_0 Peptidase family C25 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 310.0
HFD3_k127_4038095_1 cellulose binding K01179,K21449 - 3.2.1.4 0.00000000002716 70.0
HFD3_k127_4040357_0 intracellular signal transduction - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 537.0
HFD3_k127_4040357_1 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000003001 186.0
HFD3_k127_4040357_2 F420H(2)-dependent quinone reductase - - - 0.00000000000000000000000000000000000000000000002545 175.0
HFD3_k127_4040357_3 SCP-2 sterol transfer family - - - 0.0000000000000000000000000000001526 136.0
HFD3_k127_4040357_4 FMN binding K03809 - 1.6.5.2 0.0000000000000000000000001033 113.0
HFD3_k127_4049647_0 TIGRFAM cysteine desulfurase family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 503.0
HFD3_k127_4049647_1 Formiminotransferase domain, N-terminal subdomain K00603,K13990 - 2.1.2.5,4.3.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000648 291.0
HFD3_k127_4050908_0 PFAM IstB domain protein ATP-binding protein K02315 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008889 435.0
HFD3_k127_4050908_1 TIGRFAM primosome, DnaD subunit - - - 0.0000000000000000000000000000000000000000000000000005059 191.0
HFD3_k127_4050908_2 Extradiol ring-cleavage dioxygenase, class III K06990,K09141 - - 0.0000000000000347 75.0
HFD3_k127_4050963_0 Beta-ketoacyl synthase, C-terminal domain K04786,K13613 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005259 604.0
HFD3_k127_4050963_1 synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007779 546.0
HFD3_k127_4050963_2 4'-phosphopantetheinyl transferase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 551.0
HFD3_k127_4050963_3 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000796 517.0
HFD3_k127_4050963_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 340.0
HFD3_k127_4050963_5 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 323.0
HFD3_k127_4050963_6 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 313.0
HFD3_k127_4050963_7 Cobyrinic acid a,c-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000001207 191.0
HFD3_k127_4054417_0 PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein K01740 - 2.5.1.49 1.311e-200 629.0
HFD3_k127_4054417_1 B3/4 domain - - - 0.0000355 46.0
HFD3_k127_4056886_0 alpha/beta hydrolase fold K01561 - 3.8.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006674 407.0
HFD3_k127_4056886_1 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003071 258.0
HFD3_k127_4056886_2 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01190 - 3.2.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000126 259.0
HFD3_k127_4056886_3 protein ubiquitination K10297 - - 0.0001219 51.0
HFD3_k127_4064768_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 6.912e-250 811.0
HFD3_k127_4064768_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 479.0
HFD3_k127_4064768_2 Hydrolase K20862 - 3.1.3.102,3.1.3.104 0.000000000008598 71.0
HFD3_k127_4068793_0 Belongs to the binding-protein-dependent transport system permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 329.0
HFD3_k127_4068793_1 Amidohydrolase K03392 - 4.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 299.0
HFD3_k127_4068793_2 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000001845 205.0
HFD3_k127_4086701_0 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 461.0
HFD3_k127_4086701_1 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003123 426.0
HFD3_k127_4086701_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 381.0
HFD3_k127_4086701_3 Protein of unknown function (DUF1385) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003493 283.0
HFD3_k127_4086701_4 Aminotransferase K00812,K22457 GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297 2.6.1.1,2.6.1.14 0.00000000000000000001334 107.0
HFD3_k127_4086701_5 Cupin domain - - - 0.000000000001867 73.0
HFD3_k127_4111047_0 Transposase IS116 IS110 IS902 - - - 0.00000000000000000000000000000000000000000000000000000000000000000005314 247.0
HFD3_k127_4111047_1 peroxiredoxin activity - - - 0.000000000000000001174 92.0
HFD3_k127_4111474_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 4.486e-227 715.0
HFD3_k127_4111474_1 positive regulation of growth K19687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000166 292.0
HFD3_k127_4111474_2 Protein of unknown function (DUF1684) K09164 - - 0.000000000000000000000000000000000000000000000008329 176.0
HFD3_k127_4111474_4 Psort location Cytoplasmic, score 7.50 - - - 0.00006103 55.0
HFD3_k127_4113206_0 Oxidoreductase family, C-terminal alpha/beta domain K00010 - 1.1.1.18,1.1.1.369 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005609 420.0
HFD3_k127_4113206_1 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852,K00856,K10710,K22026 - 2.7.1.15,2.7.1.20,2.7.1.213,2.7.1.218,2.7.1.73 0.000000000000000000000000000000000000000000000000000000000006406 213.0
HFD3_k127_4113206_2 - - - - 0.000000001532 69.0
HFD3_k127_4125109_0 Transmembrane secretion effector K08225 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004201 388.0
HFD3_k127_4125109_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003616 368.0
HFD3_k127_4125109_2 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000004382 207.0
HFD3_k127_4125109_3 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.00000000000000000000000000000000002956 139.0
HFD3_k127_4125109_4 Protein of unknown function (DUF952) - - - 0.0000000000000000002839 91.0
HFD3_k127_4125109_5 - - - - 0.000000005694 61.0
HFD3_k127_4125109_6 - - - - 0.000004234 51.0
HFD3_k127_4125109_7 helix_turn_helix, Lux Regulon K03556 - - 0.000008758 48.0
HFD3_k127_4129605_0 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 318.0
HFD3_k127_4129605_1 alpha beta - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 327.0
HFD3_k127_4129605_2 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 313.0
HFD3_k127_4131328_0 PFAM LmbE family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000004244 235.0
HFD3_k127_4131328_1 Alpha/beta hydrolase of unknown function (DUF1057) - - - 0.00000000000000000000000000000000000002421 162.0
HFD3_k127_4131328_2 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000004994 139.0
HFD3_k127_4139252_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 1.448e-253 788.0
HFD3_k127_4139252_1 arylsulfatase A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 394.0
HFD3_k127_4139252_2 arylsulfatase A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 353.0
HFD3_k127_4143870_0 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 419.0
HFD3_k127_4143870_1 carbohydrate transport K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008357 402.0
HFD3_k127_4143870_2 glycerophosphodiester transmembrane transport K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004648 329.0
HFD3_k127_4143870_3 Binding-protein-dependent transport system inner membrane component K02025,K15771 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 300.0
HFD3_k127_4143870_4 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006165 276.0
HFD3_k127_4143870_5 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008304 275.0
HFD3_k127_4143870_6 peptidase dimerisation domain protein K01295 - 3.4.17.11 0.0000000000000000000000000000000000000000000000001561 184.0
HFD3_k127_4156771_0 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000000000000000003472 220.0
HFD3_k127_4156771_1 Protein of unknown function (DUF3048) C-terminal domain - - - 0.000000000000000000000000000000000000000001626 172.0
HFD3_k127_4156771_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000003107 149.0
HFD3_k127_4160092_0 arsenical-resistance protein K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004759 376.0
HFD3_k127_4160092_1 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07668 GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000001351 179.0
HFD3_k127_4160092_2 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000004301 167.0
HFD3_k127_4160092_3 Histidine kinase K11383 - 2.7.13.3 0.000000000000000000000000000000000000000000008386 185.0
HFD3_k127_4160092_4 PFAM regulatory protein, ArsR K03892 - - 0.000000000000000000000000000000000000001007 151.0
HFD3_k127_4169127_0 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 407.0
HFD3_k127_4169127_1 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005164 402.0
HFD3_k127_4169127_2 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006432 344.0
HFD3_k127_4169127_3 Peptidase M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009124 257.0
HFD3_k127_4169127_4 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000239 250.0
HFD3_k127_4169127_5 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000000002076 134.0
HFD3_k127_4188790_0 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004918 512.0
HFD3_k127_4188790_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 453.0
HFD3_k127_4188790_2 Required for morphogenesis under gluconeogenic growth conditions - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005551 346.0
HFD3_k127_4188790_3 Hemerythrin HHE cation binding domain K07216 - - 0.00000002929 58.0
HFD3_k127_4193546_0 Catalyzes the transfer of the amino group of L-glutamate to LysW -aminoadipate 6-semialdehyde, generating LysW -gamma-L- lysine K05830 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 477.0
HFD3_k127_4193546_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K01919,K03072,K12257 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 6.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009286 436.0
HFD3_k127_4193546_10 EamA-like transporter family K08978 - - 0.000000000000001856 82.0
HFD3_k127_4193546_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 409.0
HFD3_k127_4193546_3 Catalyzes the release of L-lysine from LysW -gamma-L- lysine K05831 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 361.0
HFD3_k127_4193546_4 Belongs to the acetylglutamate kinase family. LysZ subfamily K05828 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 324.0
HFD3_k127_4193546_5 PFAM Polynucleotide adenylyltransferase region K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 301.0
HFD3_k127_4193546_6 PFAM Stage II sporulation E family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008383 249.0
HFD3_k127_4193546_7 Protein conserved in bacteria - - - 0.000000000000000000000000000003289 129.0
HFD3_k127_4193546_8 PFAM Histidine triad (HIT) protein K02503 - - 0.0000000000000000000000000000394 123.0
HFD3_k127_4193546_9 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis - - - 0.00000000000000000000000166 108.0
HFD3_k127_41969_0 Belongs to the UbiD family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 331.0
HFD3_k127_41969_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K00320 - 1.5.98.2 0.00000000000000000000000000000000000000000000000000000000000000000002375 244.0
HFD3_k127_41969_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000001921 88.0
HFD3_k127_4220321_0 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002925 535.0
HFD3_k127_4220321_1 DegT/DnrJ/EryC1/StrS aminotransferase family K13010 - 2.6.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006273 483.0
HFD3_k127_4220321_2 PFAM lipopolysaccharide biosynthesis protein K08253 - 2.7.10.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 307.0
HFD3_k127_4220321_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001011 286.0
HFD3_k127_4220321_4 PFAM Glycosyl transferase, group 1 K03208 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001539 262.0
HFD3_k127_4220321_5 Bacterial sugar transferase - - - 0.000000000000000000000000000000000000000000000000005946 188.0
HFD3_k127_4220321_6 Methionine biosynthesis protein MetW - - - 0.0000000000001179 81.0
HFD3_k127_4226738_0 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000001438 155.0
HFD3_k127_4226738_1 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000002304 132.0
HFD3_k127_4226738_2 COG0438 Glycosyltransferase - - - 0.00000000000000000000000001956 116.0
HFD3_k127_4234654_0 BNR repeat-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009608 426.0
HFD3_k127_4234654_1 Belongs to the UPF0173 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000003844 237.0
HFD3_k127_4237862_0 serine-type peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 400.0
HFD3_k127_4237862_1 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002163 261.0
HFD3_k127_4237862_2 fatty acid desaturase K03921 - 1.14.19.11,1.14.19.2,1.14.19.26 0.00000000000000000000000000000000000002223 148.0
HFD3_k127_4243949_0 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001181 280.0
HFD3_k127_4243949_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000002079 150.0
HFD3_k127_4259422_0 major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005649 378.0
HFD3_k127_4259422_1 PFAM LmbE family protein - - - 0.000000000000000000000000000000000000000000000000000002236 198.0
HFD3_k127_4259422_2 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000009752 108.0
HFD3_k127_4259422_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000142 59.0
HFD3_k127_426379_0 MBOAT, membrane-bound O-acyltransferase family K19294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 460.0
HFD3_k127_426379_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001958 253.0
HFD3_k127_426379_2 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000000000000000000001984 113.0
HFD3_k127_426379_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000003667 59.0
HFD3_k127_4267369_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531,K01537,K12952 - 3.6.3.2,3.6.3.8 4.985e-232 744.0
HFD3_k127_4267369_1 protein histidine kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004258 433.0
HFD3_k127_4267369_2 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005787 333.0
HFD3_k127_4267369_3 Ferric reductase like transmembrane component - - - 0.00000000000000000000000000000000000000000000000000000000000121 217.0
HFD3_k127_4267369_4 Peptidoglycan-binding LysM - - - 0.000000000000000000000000000000000000000000000013 186.0
HFD3_k127_4267369_5 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000003285 78.0
HFD3_k127_4287135_0 tRNA synthetase, class II (D, K and N) K01893 - 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 593.0
HFD3_k127_4287135_1 PFAM transglutaminase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000005574 246.0
HFD3_k127_4287135_2 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.00006711 46.0
HFD3_k127_4294066_0 Transcriptional activator domain - - - 8.635e-268 855.0
HFD3_k127_4294066_1 translation release factor activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 408.0
HFD3_k127_4294066_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000002037 177.0
HFD3_k127_4294066_3 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000186 128.0
HFD3_k127_4294066_4 COG1977 Molybdopterin converting factor, small subunit - - - 0.0000000000005036 74.0
HFD3_k127_4337136_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007245 601.0
HFD3_k127_4337136_1 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000007582 86.0
HFD3_k127_4337136_2 PFAM peptidase M4 thermolysin - - - 0.0000001105 63.0
HFD3_k127_4363353_0 4Fe-4S dicluster domain K00125,K03646 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000746 197.0
HFD3_k127_4363353_1 acyl-CoA dehydrogenase - - - 0.0000000000000000001005 93.0
HFD3_k127_4363353_2 4Fe-4S dicluster domain K00125,K03646 - 1.17.1.9 0.0000000000000000007326 90.0
HFD3_k127_437686_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009259 468.0
HFD3_k127_437686_1 - - - - 0.0000000000000000000000000007829 118.0
HFD3_k127_437686_2 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000001034 55.0
HFD3_k127_4388606_0 Aldehyde dehydrogenase family K04021,K13922 GO:0003674,GO:0003824,GO:0004029,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009219 481.0
HFD3_k127_4388606_1 short-chain dehydrogenase reductase SDR K12454 - 5.1.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004253 444.0
HFD3_k127_4388606_10 GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000001573 200.0
HFD3_k127_4388606_11 Class II aldolase adducin family protein K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000867 187.0
HFD3_k127_4388606_12 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000000000000000000000000003672 183.0
HFD3_k127_4388606_13 Response regulator receiver - - - 0.0000000000000000000000000000000006351 135.0
HFD3_k127_4388606_14 Protein of unknown function (DUF503) K09764 - - 0.00000000000000000000000000005261 118.0
HFD3_k127_4388606_15 Ethanolamine utilisation protein EutN/carboxysome - - - 0.000000000000000008817 89.0
HFD3_k127_4388606_16 Ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.00000000000000001875 86.0
HFD3_k127_4388606_17 - - - - 0.0000001698 57.0
HFD3_k127_4388606_2 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 415.0
HFD3_k127_4388606_3 PFAM glycoside hydrolase, family 1 K05350 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007374 395.0
HFD3_k127_4388606_4 ethanolamine catabolic process K04024 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 340.0
HFD3_k127_4388606_5 ethanolamine catabolic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007857 331.0
HFD3_k127_4388606_6 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 349.0
HFD3_k127_4388606_7 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005993 361.0
HFD3_k127_4388606_8 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 346.0
HFD3_k127_4388606_9 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000004097 240.0
HFD3_k127_439053_0 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006622 441.0
HFD3_k127_439053_1 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 420.0
HFD3_k127_439053_2 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000002409 225.0
HFD3_k127_439053_3 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000001273 218.0
HFD3_k127_4391183_0 tagaturonate epimerase K21619 - 5.1.2.7 5.962e-198 628.0
HFD3_k127_4391183_1 lactate racemase activity K22373 - 5.1.2.1 7.234e-194 610.0
HFD3_k127_4391183_2 iron ion homeostasis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 524.0
HFD3_k127_4391183_3 Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006144 324.0
HFD3_k127_4391183_4 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006607 275.0
HFD3_k127_4391183_5 Phage shock protein A K03969 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001576 256.0
HFD3_k127_4434730_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000604 374.0
HFD3_k127_4434730_1 Rieske [2Fe-2S] domain K02636 - 1.10.9.1 0.000000000000000000000000000000000003074 147.0
HFD3_k127_4434730_2 GIY-YIG catalytic domain protein K07461 - - 0.000000000000000000001998 97.0
HFD3_k127_4434730_3 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.00000000000001982 79.0
HFD3_k127_4464302_0 PFAM alpha amylase, catalytic K01208 - 3.2.1.133,3.2.1.135,3.2.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 439.0
HFD3_k127_4464302_1 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003959 428.0
HFD3_k127_4464302_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000005173 75.0
HFD3_k127_448775_0 DNA Topoisomerase I (eukaryota) K03163 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004884 463.0
HFD3_k127_448775_1 Belongs to the binding-protein-dependent transport system permease family K01997,K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004181 443.0
HFD3_k127_448775_2 Belongs to the binding-protein-dependent transport system permease family K01997,K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 317.0
HFD3_k127_448775_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004061 263.0
HFD3_k127_45170_0 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 347.0
HFD3_k127_45170_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000001905 201.0
HFD3_k127_45170_2 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000001078 137.0
HFD3_k127_45170_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K13888 - - 0.0000000000000000000000000000002289 137.0
HFD3_k127_45170_4 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000000000000005022 87.0
HFD3_k127_454956_0 STAS domain K17763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009519 318.0
HFD3_k127_454956_1 WD domain, G-beta repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 306.0
HFD3_k127_454956_2 Stage II sporulation protein E K05518 - 3.1.3.3 0.00000000000000000000000000000000000000000000000002625 183.0
HFD3_k127_454956_3 PFAM Sulfate transporter antisigma-factor antagonist STAS K17762 - - 0.000000000000000000000000000000000000000000003291 167.0
HFD3_k127_454956_4 Histidine kinase-like ATPases K17752 - 2.7.11.1 0.00000000000000000000000000000000000000000002342 168.0
HFD3_k127_45645_0 Benzoyl-CoA reductase 2-hydroxyglutaryl-CoA dehydratase subunit, BcrC BadD HgdB K04113 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 456.0
HFD3_k127_45645_1 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.000000000000000000000000000000000000000000008526 173.0
HFD3_k127_45645_2 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00007494 46.0
HFD3_k127_4577289_0 Molydopterin dinucleotide binding domain K00123,K00336 - 1.17.1.9,1.6.5.3 1.942e-238 767.0
HFD3_k127_4577289_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000152 162.0
HFD3_k127_4577289_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000003176 103.0
HFD3_k127_4586540_0 Uncharacterized membrane protein (DUF2298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 388.0
HFD3_k127_4586540_2 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000001033 168.0
HFD3_k127_4586540_3 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000001022 141.0
HFD3_k127_4586540_4 Periplasmic copper-binding protein (NosD) - - - 0.0000002548 63.0
HFD3_k127_463215_0 Non-ribosomal peptide synthetase modules and related - - - 0.0 1246.0
HFD3_k127_463215_1 Belongs to the RtcB family K14415 - 6.5.1.3 5.931e-209 658.0
HFD3_k127_463215_10 Condensation domain - - - 0.0000000000000000000000007509 108.0
HFD3_k127_463215_11 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01733 - 4.2.3.1 0.00000000000000000000002254 108.0
HFD3_k127_463215_12 Regulatory protein MarR - - - 0.0000000000005257 75.0
HFD3_k127_463215_14 Belongs to the glycosyl hydrolase 2 family K01190 - 3.2.1.23 0.000224 54.0
HFD3_k127_463215_2 sh3 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000601 426.0
HFD3_k127_463215_3 Leucine carboxyl methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 381.0
HFD3_k127_463215_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007424 318.0
HFD3_k127_463215_5 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 298.0
HFD3_k127_463215_6 PFAM molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004504 292.0
HFD3_k127_463215_7 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007361 282.0
HFD3_k127_463215_8 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000004207 186.0
HFD3_k127_463215_9 Belongs to the P-Pant transferase superfamily K06133 - - 0.0000000000000000000000000000000000000000000000001903 186.0
HFD3_k127_4655664_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000887 470.0
HFD3_k127_4655664_1 Belongs to the phosphoglycerate mutase family K22305 - 3.1.3.3 0.00000000000000000000000000000000000000000000005131 176.0
HFD3_k127_4655664_2 FGGY family of carbohydrate kinases, N-terminal domain K00851 - 2.7.1.12 0.00000000000003001 78.0
HFD3_k127_4661994_0 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 1.589e-272 844.0
HFD3_k127_4661994_1 Belongs to the carbamoyltransferase HypF family K04656 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003185 372.0
HFD3_k127_4667315_0 PFAM ABC transporter transmembrane region K06147 - - 1.767e-259 815.0
HFD3_k127_4667315_1 PFAM ABC transporter transmembrane region K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 491.0
HFD3_k127_4667315_2 PFAM regulatory protein, MarR - - - 0.000000000864 64.0
HFD3_k127_4671304_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain K03520,K11177 - 1.17.1.4,1.2.5.3 1.457e-241 769.0
HFD3_k127_4671304_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005589 400.0
HFD3_k127_4671304_10 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 325.0
HFD3_k127_4671304_11 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 325.0
HFD3_k127_4671304_12 PFAM Aminotransferase class I and II K10907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 321.0
HFD3_k127_4671304_13 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034,K15582 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 318.0
HFD3_k127_4671304_14 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 297.0
HFD3_k127_4671304_15 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 301.0
HFD3_k127_4671304_16 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004384 289.0
HFD3_k127_4671304_17 PFAM Dimethylmenaquinone methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000279 271.0
HFD3_k127_4671304_18 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000462 285.0
HFD3_k127_4671304_19 CO dehydrogenase flavoprotein C-terminal domain K11178 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000001378 271.0
HFD3_k127_4671304_2 COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 382.0
HFD3_k127_4671304_20 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005033 276.0
HFD3_k127_4671304_21 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000161 258.0
HFD3_k127_4671304_22 MmgE PrpD family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001717 266.0
HFD3_k127_4671304_23 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000001487 246.0
HFD3_k127_4671304_24 Membrane dipeptidase (Peptidase family M19) - - - 0.00000000000000000000000000000000000000000000000000000000000000001711 237.0
HFD3_k127_4671304_25 NMT1/THI5 like - - - 0.0000000000000000000000000000000000000000000000000000000007359 210.0
HFD3_k127_4671304_26 2-keto-3-deoxy-L-rhamnonate aldolase activity K02510,K12660 - 4.1.2.52,4.1.2.53 0.0000000000000000000000000000000000000000000000000000000119 206.0
HFD3_k127_4671304_27 2Fe-2S -binding K13483 - - 0.00000000000000000000000000000000000000000000000001397 184.0
HFD3_k127_4671304_28 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000008799 190.0
HFD3_k127_4671304_29 Creatininase K01470,K22232 - 3.5.2.10 0.00000000000000000000000000000000000000000002848 171.0
HFD3_k127_4671304_3 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003999 373.0
HFD3_k127_4671304_30 Transcriptional regulator IclR K13641 - - 0.000000000000000000000000000000000000000001067 168.0
HFD3_k127_4671304_31 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000001794 136.0
HFD3_k127_4671304_32 Aldolase/RraA K10218 - 4.1.3.17 0.0000000000000000000000000000003221 132.0
HFD3_k127_4671304_33 Cro/C1-type HTH DNA-binding domain - - - 0.000000000000000000000000007331 117.0
HFD3_k127_4671304_34 NAD NADP octopine nopaline dehydrogenase, alpha-helical domain K04940 - 1.5.1.28 0.000000000000000000001091 102.0
HFD3_k127_4671304_35 PFAM Aminotransferase class I and II K00812,K10907 - 2.6.1.1 0.0000000000000000002659 100.0
HFD3_k127_4671304_36 Pfam:Methyltransf_6 K10218 - 4.1.3.17 0.00000000000000001672 83.0
HFD3_k127_4671304_37 Magnesium chelatase, subunit ChlI C-terminal K06400,K07391 - - 0.000000002194 60.0
HFD3_k127_4671304_38 transposition K07497 - - 0.000000006422 61.0
HFD3_k127_4671304_39 Bacterial periplasmic substrate-binding proteins K02030 - - 0.00005064 49.0
HFD3_k127_4671304_4 NAD(P)-binding Rossmann-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004156 364.0
HFD3_k127_4671304_40 Cupin domain - - - 0.00008218 50.0
HFD3_k127_4671304_5 COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily K01683 - 4.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 361.0
HFD3_k127_4671304_6 TIGRFAM gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 369.0
HFD3_k127_4671304_7 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033,K15581 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005193 346.0
HFD3_k127_4671304_8 S-adenosylhomocysteine deaminase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 349.0
HFD3_k127_4671304_9 Bacterial extracellular solute-binding proteins, family 5 Middle K13889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 338.0
HFD3_k127_4675961_0 protein methyltransferase activity K11434,K15984,K20421 - 2.1.1.242,2.1.1.303,2.1.1.319 0.00000000000000000000000000000000000000000000000000000000000000000000000000005348 263.0
HFD3_k127_4675961_1 MoeA domain protein domain I and II K03750,K07219 - 2.10.1.1 0.00000000000000000000000000000000000000000000000007329 191.0
HFD3_k127_4678785_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004849 496.0
HFD3_k127_4678785_1 Iron permease FTR1 family K07243 - - 0.00000000000000000000000000000000000000000000000000003833 197.0
HFD3_k127_4678785_2 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon K03709 - - 0.00000000000000000000000000000000000000000000004096 177.0
HFD3_k127_4678785_3 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000000000000000754 175.0
HFD3_k127_4678785_4 Double zinc ribbon - - - 0.0000000000000000000000000000000000000004924 156.0
HFD3_k127_4678785_5 GAF domain K01768,K02584,K07183,K22010 - 4.6.1.1 0.0000000000000000000000000000001366 129.0
HFD3_k127_4688275_0 - - - - 0.00000000000000000000000000000000000000000000000002558 194.0
HFD3_k127_4688275_1 PFAM metal-dependent phosphohydrolase, HD sub domain K06950 - - 0.000000000000000000000000000000000000000000002726 173.0
HFD3_k127_4688275_2 PFAM DNA repair protein RadC K03630 - - 0.000000000000000000000000000000000000000004788 156.0
HFD3_k127_4688275_3 Acylphosphatase K01512 - 3.6.1.7 0.0000000000000000000000002977 107.0
HFD3_k127_4688275_4 nitrogen fixation - - - 0.0000000000000000000001795 102.0
HFD3_k127_4688275_5 - - - - 0.0000000001393 64.0
HFD3_k127_4703887_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000003168 245.0
HFD3_k127_4703887_1 Predicted membrane protein (DUF2079) - - - 0.00000000000000000000000000000000000000000008613 175.0
HFD3_k127_4719682_0 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001424 278.0
HFD3_k127_4719682_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005497 253.0
HFD3_k127_4725933_0 PFAM O-antigen polymerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 397.0
HFD3_k127_4725933_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000002958 141.0
HFD3_k127_4725933_2 Psort location CytoplasmicMembrane, score 10.00 - - - 0.000000000000000000009167 95.0
HFD3_k127_4739484_0 electron transfer activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 610.0
HFD3_k127_4739484_1 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 378.0
HFD3_k127_4739484_2 Histidine kinase K07675,K11623 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 318.0
HFD3_k127_4739484_3 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002418 267.0
HFD3_k127_4739484_4 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000001314 229.0
HFD3_k127_4739484_5 nitrite reductase [NAD(P)H] activity - - - 0.000000000000000000000000000000000000000000000000000000000000001441 228.0
HFD3_k127_4739484_6 - K07092 - - 0.000000000000000000000000000000000000000000000000000000002087 203.0
HFD3_k127_4739484_7 LysM domain - - - 0.0000000000000000000000000000000000000000000000000000002184 211.0
HFD3_k127_4739484_8 LysM domain - - - 0.0000000000000000000000000000000000000000000000000002486 202.0
HFD3_k127_4739484_9 Belongs to the sulfur carrier protein TusA family - - - 0.000000000000000000000000000000008683 128.0
HFD3_k127_4741314_0 Domain of unknown function (DUF4032) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003183 249.0
HFD3_k127_4741314_1 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000003671 208.0
HFD3_k127_4741314_2 Uncharacterised MFS-type transporter YbfB - - - 0.000000000000000000000000000000000000000000000000000001256 198.0
HFD3_k127_4741314_3 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.000000000000000000000003229 104.0
HFD3_k127_4741314_4 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.000000000000000000001806 103.0
HFD3_k127_4745905_0 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 466.0
HFD3_k127_4745905_1 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000413 445.0
HFD3_k127_4745905_2 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 404.0
HFD3_k127_4745905_3 nitrogen compound transport K02033 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 334.0
HFD3_k127_4745905_4 N-terminal TM domain of oligopeptide transport permease C K15582 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005433 282.0
HFD3_k127_4745905_5 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004132 276.0
HFD3_k127_4745905_6 Mo-co oxidoreductase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005752 264.0
HFD3_k127_4745905_7 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K08738 - - 0.000000001759 66.0
HFD3_k127_4746381_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 4.076e-304 954.0
HFD3_k127_4746381_1 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 310.0
HFD3_k127_4746381_2 PFAM CMP dCMP deaminase zinc-binding K01493 - 3.5.4.12 0.000000000000000000000000000000000000000000000000003197 185.0
HFD3_k127_4746381_3 PFAM aspartate glutamate uridylate kinase K06981 - 2.7.4.26 0.00000000000000000000000000000000000000000005566 168.0
HFD3_k127_4746381_4 - - - - 0.00000000000000000000000006375 113.0
HFD3_k127_4748376_0 sh3 domain protein K01227,K03642 - 3.2.1.96 0.00000000000000000000000000000000000000000002023 172.0
HFD3_k127_4748376_1 diguanylate cyclase - - - 0.00000000000000000000000000000000000007078 160.0
HFD3_k127_4748376_2 Methyltransferase, YaeB - - - 0.00000000000000000000000000008624 121.0
HFD3_k127_4749541_0 Xylose isomerase-like TIM barrel K10709 - - 0.00000000000000000000000000000000000000000000000000000000000000001005 233.0
HFD3_k127_4749541_1 - - - - 0.0000000000000000000000000000000000000000000000000000003319 201.0
HFD3_k127_4749541_2 PAS domain - - - 0.000000000000000000000000000000002061 132.0
HFD3_k127_4749541_3 Belongs to the metallo-dependent hydrolases superfamily. NagA family - - - 0.00000000000000004168 86.0
HFD3_k127_4755494_0 PFAM glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008752 314.0
HFD3_k127_4755494_1 - - - - 0.00000000000000000000000000000000000000000000000008331 195.0
HFD3_k127_4755494_2 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000006333 134.0
HFD3_k127_4755494_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000003225 133.0
HFD3_k127_4755494_4 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000003316 90.0
HFD3_k127_4773835_0 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005041 387.0
HFD3_k127_4773835_1 modification enzyme, MiaB family K18707 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004498 354.0
HFD3_k127_4773835_2 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 286.0
HFD3_k127_4773835_3 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001632 259.0
HFD3_k127_4773835_4 SMART HNH nuclease - - - 0.000000000000000000000000000000000000000000000000000000000000567 215.0
HFD3_k127_4773835_5 Pfam:DUF3816 - - - 0.0000000000000000000000000000000000000000000000000000006969 198.0
HFD3_k127_4773835_6 PFAM Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000001823 175.0
HFD3_k127_4773835_7 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000003242 149.0
HFD3_k127_4773835_8 Transmembrane secretion effector - - - 0.0000000000001217 83.0
HFD3_k127_4775904_0 Beta-lactamase K01286 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006333 291.0
HFD3_k127_4775904_1 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002498 282.0
HFD3_k127_4775904_2 COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes - - - 0.00000000000000000000000000000000000000000000000000000000007773 215.0
HFD3_k127_4784828_0 PFAM Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000395 371.0
HFD3_k127_4784828_1 Voltage gated chloride channel - - - 0.0000000000000000000000000000002698 127.0
HFD3_k127_4815748_0 Aminoglycoside phosphotransferase - - - 0.000000000000000000000000000000000000001928 162.0
HFD3_k127_4815748_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000004986 60.0
HFD3_k127_4819802_0 PFAM conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009963 254.0
HFD3_k127_4819802_1 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000004618 221.0
HFD3_k127_4819802_2 Amidase - - - 0.000000000000009196 79.0
HFD3_k127_4835405_0 glutamine synthetase K01915 GO:0001968,GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009405,GO:0009605,GO:0009607,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019222,GO:0019752,GO:0019899,GO:0020012,GO:0030162,GO:0030312,GO:0030682,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0035375,GO:0040007,GO:0043207,GO:0043436,GO:0044044,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0071944,GO:0075136,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903317,GO:1903319 6.3.1.2 2.363e-220 700.0
HFD3_k127_4835405_1 Ammonium Transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009997 600.0
HFD3_k127_4835405_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 417.0
HFD3_k127_4835405_3 Dihydrodipicolinate reductase, N-terminus K21672 - 1.4.1.12,1.4.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 335.0
HFD3_k127_4835405_4 Asparaginase glutaminase K01424 - 3.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006562 276.0
HFD3_k127_4835405_5 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000001066 239.0
HFD3_k127_4835405_6 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000000001758 187.0
HFD3_k127_4835405_7 LysE type translocator - - - 0.0000000000000000000000000000000003307 141.0
HFD3_k127_4838029_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007644 590.0
HFD3_k127_4838029_1 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000002079 243.0
HFD3_k127_4838029_2 Histidine kinase K07683 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000002402 203.0
HFD3_k127_4838029_3 PFAM regulatory protein TetR - - - 0.000000000000000000000000000000000000000000564 165.0
HFD3_k127_4838029_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042886,GO:0042887,GO:0043953,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.0000000000000000000000000007499 123.0
HFD3_k127_4838029_5 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000002582 111.0
HFD3_k127_4838029_6 diguanylate cyclase - - - 0.000000000000001028 89.0
HFD3_k127_4838029_7 mttA/Hcf106 family K03116 - - 0.000000003769 61.0
HFD3_k127_4838029_8 protein secretion K03116,K03117 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000008907 55.0
HFD3_k127_4859769_0 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.000000000000000000000000000000000000000000000000000000000000000001198 241.0
HFD3_k127_4859769_1 AMP-binding enzyme C-terminal domain K04110 - 6.2.1.25 0.000000000000000000000000000000000000000000000000000000000000008163 218.0
HFD3_k127_4861821_0 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 518.0
HFD3_k127_4861821_1 PFAM Dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008693 334.0
HFD3_k127_4866592_0 Bacterial toxin of type II toxin-antitoxin system, YafQ - - - 0.00000000000000000000000000006312 119.0
HFD3_k127_4866592_1 - - - - 0.00000000000000000000000001042 119.0
HFD3_k127_4866592_2 Acid phosphatase homologues - - - 0.000000000000005388 78.0
HFD3_k127_4866592_3 Protein of unknown function (DUF2892) - - - 0.0000006536 54.0
HFD3_k127_4871263_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 3.831e-218 688.0
HFD3_k127_4871263_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 2.17e-205 645.0
HFD3_k127_4871263_2 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000003169 136.0
HFD3_k127_4878984_0 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004792 354.0
HFD3_k127_48794_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 7.824e-265 826.0
HFD3_k127_48794_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 443.0
HFD3_k127_48794_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007105 333.0
HFD3_k127_48794_3 - - - - 0.0002536 51.0
HFD3_k127_4880616_0 -O-antigen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004913 526.0
HFD3_k127_4880616_1 PFAM glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008031 359.0
HFD3_k127_4880616_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.000000000001212 68.0
HFD3_k127_4882520_0 pectate lyase K01728 - 4.2.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006287 443.0
HFD3_k127_4882520_1 PFAM Bacterial extracellular solute-binding K17318 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008226 415.0
HFD3_k127_4882520_2 Glycosyl Hydrolase Family 88 K15532 - 3.2.1.172 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 312.0
HFD3_k127_4892167_0 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 593.0
HFD3_k127_4892167_1 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 473.0
HFD3_k127_4892167_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K00446 - 1.13.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000374 452.0
HFD3_k127_4892167_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 449.0
HFD3_k127_4892167_4 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000007623 108.0
HFD3_k127_4893924_0 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 2.18e-321 1009.0
HFD3_k127_4893924_1 helix_turn_helix, Lux Regulon K03556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009634 606.0
HFD3_k127_4893924_2 PFAM Polysaccharide pyruvyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000031 456.0
HFD3_k127_4893924_3 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006765 315.0
HFD3_k127_4893924_4 - - - - 0.00000000000000000000000000000000000000007829 157.0
HFD3_k127_4893924_5 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000289 124.0
HFD3_k127_4893924_6 GMC oxidoreductase - - - 0.000000000000000000000000002963 113.0
HFD3_k127_4893924_7 - - - - 0.00000000000000009077 83.0
HFD3_k127_4893924_8 - - - - 0.000000000000001011 79.0
HFD3_k127_4893924_9 response regulator - - - 0.000000000001482 82.0
HFD3_k127_489856_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1319.0
HFD3_k127_489856_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 515.0
HFD3_k127_489856_2 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000656 381.0
HFD3_k127_489856_3 PFAM NAD-dependent epimerase dehydratase K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000001085 234.0
HFD3_k127_489856_4 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000000000000000001709 209.0
HFD3_k127_489856_5 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000001321 170.0
HFD3_k127_489856_6 L-phenylalanine transmembrane transporter activity K01998 - - 0.000000000000000000000000000000000000001826 154.0
HFD3_k127_489856_7 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000007116 147.0
HFD3_k127_489856_8 COG0559 Branched-chain amino acid ABC-type transport system, permease components - - - 0.00000000000000000000000002361 111.0
HFD3_k127_4908883_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 3.057e-202 646.0
HFD3_k127_4908883_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 525.0
HFD3_k127_4908883_2 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 301.0
HFD3_k127_4908883_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 291.0
HFD3_k127_4908883_4 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003561 282.0
HFD3_k127_4908883_5 Abc transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000163 276.0
HFD3_k127_4908883_6 AAA domain, putative AbiEii toxin, Type IV TA system K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001042 274.0
HFD3_k127_4908883_7 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00180 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000102 196.0
HFD3_k127_4917334_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 1.621e-249 788.0
HFD3_k127_4917334_1 Maltogenic Amylase, C-terminal domain K05343 - 3.2.1.1,5.4.99.16 2.914e-235 740.0
HFD3_k127_4917334_10 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000003461 180.0
HFD3_k127_4917334_11 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.000000000000000000000000000000000007651 148.0
HFD3_k127_4917334_12 - - - - 0.0000000000000000000000000000005727 134.0
HFD3_k127_4917334_13 C-terminal four TMM region of protein-O-mannosyltransferase - - - 0.00000000000000000000001227 117.0
HFD3_k127_4917334_14 - - - - 0.000000001024 72.0
HFD3_k127_4917334_2 Glycogen debranching enzyme - - - 2.267e-222 704.0
HFD3_k127_4917334_3 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005188 519.0
HFD3_k127_4917334_4 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 437.0
HFD3_k127_4917334_5 Glycosyltransferase family 20 K00697 - 2.4.1.15,2.4.1.347 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007725 429.0
HFD3_k127_4917334_6 Glycosyltransferase Family 4 K21369 - 2.4.1.270 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 353.0
HFD3_k127_4917334_7 PFAM DRTGG domain protein K06873 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 306.0
HFD3_k127_4917334_8 Protein of unknown function (DUF2723) K14340 - - 0.000000000000000000000000000000000000000000000000000000000000000000004079 265.0
HFD3_k127_4917334_9 Glycosyltransferase Family 4 K21369 - 2.4.1.270 0.000000000000000000000000000000000000000000000000000000000000000003188 244.0
HFD3_k127_4933103_0 Histidine kinase - - - 0.0000000000000000000000000000003505 126.0
HFD3_k127_4933103_1 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K01153,K06042,K22491 - 3.1.21.3,5.4.99.60,5.4.99.61 0.0000000000000002606 86.0
HFD3_k127_4933103_2 Protein of unknown function (DUF1232) - - - 0.00000000171 64.0
HFD3_k127_4934159_0 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 1.718e-246 782.0
HFD3_k127_4934159_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 6.959e-194 619.0
HFD3_k127_4934159_10 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000375 138.0
HFD3_k127_4934159_11 acetyltransferase - - - 0.000000000000000000000000013 113.0
HFD3_k127_4934159_12 cellulose binding K01179,K21449 - 3.2.1.4 0.00000000000706 73.0
HFD3_k127_4934159_13 Short C-terminal domain K08982 - - 0.0000002518 54.0
HFD3_k127_4934159_14 membrane protein (DUF2078) K08982 - - 0.0000005779 57.0
HFD3_k127_4934159_15 Chitinase C K01183,K21606 - 3.2.1.14,3.2.1.202 0.0001517 53.0
HFD3_k127_4934159_2 Glycosyl transferase family 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003547 420.0
HFD3_k127_4934159_3 Amino acid amide ABC transporter substrate-binding protein, HAAT family K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006395 416.0
HFD3_k127_4934159_4 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 381.0
HFD3_k127_4934159_5 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 336.0
HFD3_k127_4934159_6 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 321.0
HFD3_k127_4934159_7 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00042 - 1.1.1.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004057 316.0
HFD3_k127_4934159_8 lipid kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000001909 235.0
HFD3_k127_4934159_9 DinB family - - - 0.000000000000000000000000000000000000000000000000000000003719 203.0
HFD3_k127_4937910_0 glycogen debranching - - - 2.574e-201 646.0
HFD3_k127_4937910_1 PFAM ABC transporter related K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000984 239.0
HFD3_k127_4937910_2 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000002842 211.0
HFD3_k127_4937910_3 COG2087 Adenosyl cobinamide kinase adenosyl cobinamide phosphate guanylyltransferase K02231 - 2.7.1.156,2.7.7.62 0.00000000000000000000000000000000000000000000006842 175.0
HFD3_k127_4937910_4 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase K00950,K09007,K13940,K17488 - 2.7.6.3,3.5.4.16,3.5.4.39,4.1.2.25 0.000000000000000000000000000000000000000007367 159.0
HFD3_k127_4937910_5 Xylose isomerase-like TIM barrel - - - 0.000000000000000000006486 95.0
HFD3_k127_49435_0 ABC transporter K10441 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 536.0
HFD3_k127_49435_1 Ribose ABC superfamily ATP binding cassette transporter, permease protein K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004318 282.0
HFD3_k127_49435_2 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000000000000000000006439 179.0
HFD3_k127_49435_3 Periplasmic binding protein domain - - - 0.0000000000000000000000000003671 127.0
HFD3_k127_4947485_0 PFAM aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 3.072e-308 953.0
HFD3_k127_4947485_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000661 564.0
HFD3_k127_4947485_10 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K07025 - - 0.00000000000000000000000000000000000001764 150.0
HFD3_k127_4947485_11 Belongs to the phosphoglycerate mutase family K02226 - 3.1.3.73 0.00000000000000000000000000000000000005287 151.0
HFD3_k127_4947485_12 PFAM Phosphoglycerate mutase K22305 - 3.1.3.3 0.000000000000000000000000000000009254 136.0
HFD3_k127_4947485_13 Domain of unknown function (DUF1952) K03636 - - 0.000000000000001501 79.0
HFD3_k127_4947485_14 COG1977 Molybdopterin converting factor, small subunit - - - 0.0000000000001063 74.0
HFD3_k127_4947485_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 405.0
HFD3_k127_4947485_3 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 374.0
HFD3_k127_4947485_4 Domain of unknown function (DUF4139) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003939 377.0
HFD3_k127_4947485_5 TIGRFAM LAO AO transport system ATPase K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 331.0
HFD3_k127_4947485_6 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000001824 222.0
HFD3_k127_4947485_8 Cobalamin B12-binding K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000004508 205.0
HFD3_k127_4947485_9 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000006057 176.0
HFD3_k127_4963188_0 Glycosyltransferase 36 associated - - - 0.0 2306.0
HFD3_k127_4963188_1 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 456.0
HFD3_k127_4963188_2 involved in signal transduction (via phosphorylation) involved in transcriptional regulatory mechanism and in the regulation of secondary metabolites catalytic activity ATP a protein ADP a phosphoprotein K08282 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 367.0
HFD3_k127_4963188_3 Universal stress protein - - - 0.00000000000000000000000000000000000000000000113 177.0
HFD3_k127_4963188_4 enzyme of poly-gamma-glutamate biosynthesis (Capsule formation) K07282 - - 0.0000001116 53.0
HFD3_k127_4964978_0 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005713 321.0
HFD3_k127_4964978_1 EamA-like transporter family K03298 - - 0.000000000000000000000000000000000000000000000000000003093 202.0
HFD3_k127_4964978_2 - - - - 0.00000000000000000000000001541 119.0
HFD3_k127_4964978_3 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases K02236,K02654 - 3.4.23.43 0.00000000000000005431 91.0
HFD3_k127_4967306_0 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007229 599.0
HFD3_k127_4967306_1 TIGRFAM cation diffusion facilitator family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007937 330.0
HFD3_k127_4967306_4 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000002667 157.0
HFD3_k127_4967306_5 Rieske [2Fe-2S] domain - - - 0.00000000000000000003355 104.0
HFD3_k127_4967306_6 COG2146 Ferredoxin subunits of nitrite reductase and K00363 - 1.7.1.15 0.0000000000000000003388 101.0
HFD3_k127_4986832_0 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 328.0
HFD3_k127_4986832_1 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 321.0
HFD3_k127_4986832_2 Periplasmic binding protein domain K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004564 271.0
HFD3_k127_4986832_3 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000006542 230.0
HFD3_k127_4986832_4 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000002256 159.0
HFD3_k127_5082027_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007384 390.0
HFD3_k127_5082027_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003654 282.0
HFD3_k127_5082027_2 RecR protein K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007666 276.0
HFD3_k127_5082027_3 TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family - - - 0.000000000000000000000000000000000000000000000000000000000000000001129 244.0
HFD3_k127_5082027_4 Signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000002207 181.0
HFD3_k127_5082027_5 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000006676 104.0
HFD3_k127_5082027_6 Domain of unknown function (DUF4115) - - - 0.000000000004007 79.0
HFD3_k127_5082027_7 - - - - 0.000000002533 60.0
HFD3_k127_5082027_8 - - - - 0.0000001465 53.0
HFD3_k127_5083566_0 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009607 520.0
HFD3_k127_5083566_1 Pfam:Kce K18013 - 2.3.1.247 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 417.0
HFD3_k127_5083566_10 Cupin domain - - - 0.00000000002014 68.0
HFD3_k127_5083566_2 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006254 384.0
HFD3_k127_5083566_3 PFAM inner-membrane translocator K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007769 359.0
HFD3_k127_5083566_4 transport system permease K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009817 331.0
HFD3_k127_5083566_5 PFAM ABC transporter related K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 286.0
HFD3_k127_5083566_6 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.00000000000000000000000000000000000000000000000000000000000002345 223.0
HFD3_k127_5083566_7 cyclic nucleotide binding K10914,K21563 - - 0.000000000000000000000000000000000000000000000001492 183.0
HFD3_k127_5083566_8 - - - - 0.00000000000000000000000000000000000000003168 160.0
HFD3_k127_5083566_9 FCD domain - - - 0.000000000000000000000000000000000000004576 154.0
HFD3_k127_5091551_0 SMART Elongator protein 3 MiaB NifB - - - 2.832e-237 745.0
HFD3_k127_5091551_1 MacB-like periplasmic core domain K02004 - - 6.004e-215 694.0
HFD3_k127_5091551_10 O-Antigen ligase - - - 0.0002133 52.0
HFD3_k127_5091551_2 NAD(P)H-binding K01784,K12448 - 5.1.3.2,5.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 399.0
HFD3_k127_5091551_3 PFAM transferase hexapeptide repeat containing protein K00661 - 2.3.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 315.0
HFD3_k127_5091551_4 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001062 264.0
HFD3_k127_5091551_5 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000001486 226.0
HFD3_k127_5091551_6 Lipocalin-like domain - - - 0.0000000000000000000000000000001213 128.0
HFD3_k127_5091551_7 belongs to the sigma-70 factor family, ECF subfamily - - - 0.00000000000000000000000000001129 126.0
HFD3_k127_5091551_8 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000009469 56.0
HFD3_k127_5091551_9 Tfp pilus assembly protein FimV - - - 0.00003918 55.0
HFD3_k127_5105473_0 2-oxoglutarate dehydrogenase N-terminus K00164 - 1.2.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 590.0
HFD3_k127_5105473_1 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003923 469.0
HFD3_k127_5105473_2 GTP cyclohydrolase I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002298 270.0
HFD3_k127_5141903_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 465.0
HFD3_k127_5141903_1 histidine biosynthetic process K00765,K01892,K02502 - 2.4.2.17,6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000361 303.0
HFD3_k127_5141903_2 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765,K02502 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000234 202.0
HFD3_k127_5141903_3 protein possibly involved in aromatic compounds catabolism - - - 0.0000000002397 63.0
HFD3_k127_5145512_0 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 3.393e-200 633.0
HFD3_k127_5145512_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002506 588.0
HFD3_k127_5145512_2 NapC/NirT cytochrome c family, N-terminal region K15876 - - 0.00000000000000000000000000000000000000000001938 167.0
HFD3_k127_518901_0 Cys/Met metabolism PLP-dependent enzyme K01739,K01758,K01760,K01761 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 497.0
HFD3_k127_518901_1 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003098 336.0
HFD3_k127_518901_2 Belongs to the 'phage' integrase family K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001482 278.0
HFD3_k127_518901_3 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000002419 191.0
HFD3_k127_518901_4 PFAM membrane-flanked domain - - - 0.000000000000000000000000000000000000000000000000004522 188.0
HFD3_k127_5200184_0 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000001996 193.0
HFD3_k127_5200184_1 LysM domain - - - 0.0000000000002873 79.0
HFD3_k127_5200184_2 - - - - 0.00000000002268 68.0
HFD3_k127_5203115_0 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000007625 174.0
HFD3_k127_5203115_1 VanW like protein - - - 0.00007101 55.0
HFD3_k127_5205206_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004549 381.0
HFD3_k127_5205206_1 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000006668 122.0
HFD3_k127_5205206_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.00000000000000002403 82.0
HFD3_k127_5205206_3 PFAM Transcription factor CarD K07736 - - 0.000003464 56.0
HFD3_k127_524254_0 PA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008538 301.0
HFD3_k127_524254_1 Putative stress-induced transcription regulator - - - 0.0000000000000000000000000000000000000000000000000000000006742 208.0
HFD3_k127_524254_2 oxidoreductase activity K00337,K03333,K04771,K07114 - 1.1.3.6,1.6.5.3,3.4.21.107 0.000000000000000000000000000000000000006493 151.0
HFD3_k127_524254_3 Belongs to the UPF0271 (lamB) family K07160 - - 0.000000000000000000000000008467 110.0
HFD3_k127_524254_5 Protein of unknown function (DUF1706) - - - 0.0000000000000000000005221 102.0
HFD3_k127_5259595_0 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005424 316.0
HFD3_k127_5259595_1 Phospholipase/Carboxylesterase K06999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006635 295.0
HFD3_k127_5259595_2 nucleotidyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000004577 239.0
HFD3_k127_5259595_3 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000004456 235.0
HFD3_k127_5259595_4 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179 - 3.2.1.4 0.00003213 56.0
HFD3_k127_5289317_0 PFAM Amidohydrolase 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000448 465.0
HFD3_k127_5289317_1 PFAM Glycosyl transferase family 2 K21349 - 2.4.1.268 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 303.0
HFD3_k127_5289317_2 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000005785 222.0
HFD3_k127_5289317_3 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.0000000000000000000000000000000000000000008463 162.0
HFD3_k127_5289317_4 subunit of a heme lyase K02200 - - 0.00000000000000000000000000001655 125.0
HFD3_k127_5289317_5 Mov34 MPN PAD-1 family K21140 - 3.13.1.6 0.0000000000000000000000000003266 122.0
HFD3_k127_5289317_6 Bacterial membrane protein YfhO - - - 0.0000000000000000000000000006326 125.0
HFD3_k127_5289317_7 PFAM Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000002869 74.0
HFD3_k127_5289317_8 PFAM Bacterial extracellular solute-binding protein K15770 - - 0.00001173 57.0
HFD3_k127_5330017_0 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000885 537.0
HFD3_k127_5330017_1 PFAM CBS domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008016 341.0
HFD3_k127_5330017_2 TIGRFAM mevalonate kinase K00869 - 2.7.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004945 286.0
HFD3_k127_5330017_3 PFAM Phosphatidic acid phosphatase type 2 haloperoxidase K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000005288 195.0
HFD3_k127_5330017_4 Type IV pilus biogenesis stability protein PilW - - - 0.000000000000000000000001478 111.0
HFD3_k127_5330017_5 metal-dependent membrane protease K07052 - - 0.0000000000003496 72.0
HFD3_k127_5330017_6 Lysylphosphatidylglycerol synthase TM region - - - 0.0000005991 61.0
HFD3_k127_5349652_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000814 293.0
HFD3_k127_5349652_1 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000000000000000000000000000008211 239.0
HFD3_k127_5349652_2 PFAM phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000001129 148.0
HFD3_k127_5352501_0 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000006711 215.0
HFD3_k127_5352501_1 Bacterial membrane protein YfhO - - - 0.0000000000000000006669 91.0
HFD3_k127_539616_0 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 489.0
HFD3_k127_539616_1 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005062 386.0
HFD3_k127_539616_2 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 375.0
HFD3_k127_539616_3 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004484 308.0
HFD3_k127_539616_4 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 302.0
HFD3_k127_5435684_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00016 - 1.1.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006568 393.0
HFD3_k127_5435684_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000542 376.0
HFD3_k127_5435684_10 PFAM Polyketide cyclase dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000000000000000000000005875 229.0
HFD3_k127_5435684_11 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000177 215.0
HFD3_k127_5435684_12 Domain of unknown function (DUF892) - - - 0.000000000000000000000000000000000000000000000000000001254 197.0
HFD3_k127_5435684_13 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000001356 210.0
HFD3_k127_5435684_14 - - - - 0.000000000000000000000000000000000000000000000000000002186 203.0
HFD3_k127_5435684_15 Involved in the tonB-independent uptake of proteins K03641 - - 0.0000000000000000000000000000000000000000000000000004598 201.0
HFD3_k127_5435684_16 PFAM Diacylglycerol kinase, catalytic - - - 0.00000000000000000000000000000000000000000000000001279 196.0
HFD3_k127_5435684_17 pfam cbs - - - 0.0000000000000000000000000000000425 133.0
HFD3_k127_5435684_18 Nitroreductase family - - - 0.0000000000000000000000000000002517 130.0
HFD3_k127_5435684_19 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000000000662 120.0
HFD3_k127_5435684_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01524,K07012 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 374.0
HFD3_k127_5435684_20 CHAD - - - 0.00000000000000000000000001907 121.0
HFD3_k127_5435684_21 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000000002395 117.0
HFD3_k127_5435684_22 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000001105 109.0
HFD3_k127_5435684_23 Acid phosphatase homologues - - - 0.00000000000000000000031 106.0
HFD3_k127_5435684_24 - - - - 0.00000000000000000001395 100.0
HFD3_k127_5435684_25 CsbD-like - - - 0.00000000000000007083 87.0
HFD3_k127_5435684_26 Protein of unknown function (DUF3309) - - - 0.00000000000001338 74.0
HFD3_k127_5435684_27 PRC-barrel domain - - - 0.0000000000002331 74.0
HFD3_k127_5435684_28 Endonuclease/Exonuclease/phosphatase family - - - 0.0000001057 63.0
HFD3_k127_5435684_3 pyrroloquinoline quinone binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 359.0
HFD3_k127_5435684_4 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 327.0
HFD3_k127_5435684_5 Cytochrome c7 and related cytochrome c K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005622 300.0
HFD3_k127_5435684_6 dTDP biosynthetic process K00560,K00943,K01585 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.1.1.45,2.7.4.9,4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000004161 270.0
HFD3_k127_5435684_7 Domain of Unknown Function (DUF1206) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002683 256.0
HFD3_k127_5435684_8 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000003147 243.0
HFD3_k127_5435684_9 PFAM Diacylglycerol kinase, catalytic - - - 0.00000000000000000000000000000000000000000000000000000000000000000005679 241.0
HFD3_k127_5437068_0 PFAM carbohydrate kinase K00854 - 2.7.1.17 1.244e-196 625.0
HFD3_k127_5437068_1 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000001148 113.0
HFD3_k127_5438944_0 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003944 360.0
HFD3_k127_5438944_1 4-amino-4-deoxy-L-arabinose transferase activity K14340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 290.0
HFD3_k127_5438944_2 Ferritin-like - - - 0.0000000000000000000000000000000000000000000000000000002958 201.0
HFD3_k127_5439883_0 SMART PUA domain containing protein K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 471.0
HFD3_k127_5439883_1 PFAM peptidase S58, DmpA K01266 - 3.4.11.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 331.0
HFD3_k127_5439883_10 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749 - - 0.000000000000008024 80.0
HFD3_k127_5439883_11 Trehalose utilisation - - - 0.0000008419 62.0
HFD3_k127_5439883_12 - - - - 0.00003567 57.0
HFD3_k127_5439883_2 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 339.0
HFD3_k127_5439883_3 histidine kinase, dimerisation and phosphoacceptor region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004435 293.0
HFD3_k127_5439883_4 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000001833 261.0
HFD3_k127_5439883_5 Diacylglycerol kinase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002415 254.0
HFD3_k127_5439883_6 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000219 237.0
HFD3_k127_5439883_7 Patatin-like phospholipase K01999,K07001 - - 0.00000000000000000000000000000000000000000000000000000000000006661 234.0
HFD3_k127_5439883_8 AMP binding - - - 0.0000000000000000000000000000000000000001931 160.0
HFD3_k127_5439883_9 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749,K04757 - 2.7.11.1 0.000000000000000000000000000002161 124.0
HFD3_k127_5449517_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07306,K08352 - 1.8.5.3,1.8.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009644 276.0
HFD3_k127_5449517_1 Belongs to the RNase T2 family K01166 - 3.1.27.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004186 274.0
HFD3_k127_5449517_2 TIGRFAM MazG family protein K02499 - - 0.0000000000000000000000000000000000000000000000000000000000000000001147 241.0
HFD3_k127_5449517_3 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000001716 96.0
HFD3_k127_5449517_4 regulation of translation K03530 - - 0.0000000000000000002341 95.0
HFD3_k127_5455765_0 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity K00303 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 317.0
HFD3_k127_5455765_1 COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000009435 238.0
HFD3_k127_5457624_0 Divergent PAP2 family K09775 - - 0.000000000000000000000000000000000000000000002676 169.0
HFD3_k127_5457624_1 - - - - 0.00000000000000000000000000007384 126.0
HFD3_k127_5457624_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000007072 65.0
HFD3_k127_5460756_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004084 532.0
HFD3_k127_5460756_1 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006331 371.0
HFD3_k127_5460756_2 Protein of unknown function (DUF448) K07742 - - 0.00000000000000000004142 93.0
HFD3_k127_5461744_0 PFAM ABC transporter related K06147 - - 8.806e-246 775.0
HFD3_k127_5461744_1 FAD dependent oxidoreductase central domain K19191 - 1.5.3.19 1.468e-225 725.0
HFD3_k127_5461744_10 Protein of unknown function (DUF2817) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000442 261.0
HFD3_k127_5461744_11 sulfuric ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001629 250.0
HFD3_k127_5461744_12 protein domain associated with K03595,K06883,K06946 - - 0.0000000000000000000000000000000000000000000000000000000001218 218.0
HFD3_k127_5461744_13 peptidase - - - 0.000000000000000000000000000000000000000000000000000005099 209.0
HFD3_k127_5461744_14 UTRA K03710 - - 0.0000000000000000000000000000000000000000000000269 179.0
HFD3_k127_5461744_15 BMC K04027 - - 0.000000000000000000000000000000000000000001342 161.0
HFD3_k127_5461744_16 spore germination - - - 0.00000000000000000000000000000000000000001775 165.0
HFD3_k127_5461744_17 Protein of unknown function (DUF3037) - - - 0.00000000000000000000000000000000001009 141.0
HFD3_k127_5461744_18 Ethanolamine utilisation protein EutN/carboxysome - - - 0.000000000000000000004329 96.0
HFD3_k127_5461744_19 - - - - 0.00000000000000000002905 93.0
HFD3_k127_5461744_2 Trimethylamine methyltransferase K14083 - 2.1.1.250 4.382e-195 619.0
HFD3_k127_5461744_20 transcriptional regulator PadR family K10947 - - 0.0000000000000000000441 94.0
HFD3_k127_5461744_22 - - - - 0.00000000001552 72.0
HFD3_k127_5461744_23 cob(I)yrinic acid a,c-diamide adenosyltransferase activity K04032 - 2.5.1.17 0.00003714 49.0
HFD3_k127_5461744_24 peptidase - - - 0.00004346 52.0
HFD3_k127_5461744_25 S-layer homology domain - - - 0.0004311 51.0
HFD3_k127_5461744_3 Domain of unknown function (DUF2088) K22373 - 5.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 452.0
HFD3_k127_5461744_4 Domain of unknown function (DUF4445) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008578 373.0
HFD3_k127_5461744_5 Methionine synthase B12-binding module cap domain protein K00548,K15023 - 2.1.1.13,2.1.1.258 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004124 331.0
HFD3_k127_5461744_6 Serine threonine protein kinase involved in cell cycle control - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 323.0
HFD3_k127_5461744_7 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 293.0
HFD3_k127_5461744_8 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00571,K00847,K00852 - 2.1.1.72,2.7.1.15,2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004017 281.0
HFD3_k127_5461744_9 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000954 273.0
HFD3_k127_5466701_0 Histidine kinase K00936,K02030,K10441,K13924,K20962 - 2.1.1.80,2.7.13.3,3.1.1.61,3.1.4.52,3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005006 334.0
HFD3_k127_5466701_1 PFAM response regulator receiver K22010 - - 0.000000000000000000000000000000000000000000000000001252 184.0
HFD3_k127_5466701_2 PFAM glycoside hydrolase family 39 - - - 0.00001659 55.0
HFD3_k127_5466701_3 Phage integrase, N-terminal SAM-like domain - - - 0.0001546 46.0
HFD3_k127_5469016_0 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006635 345.0
HFD3_k127_5469016_1 Lipocalin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 308.0
HFD3_k127_5469016_2 AIR synthase related protein, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 306.0
HFD3_k127_5469016_3 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002831 227.0
HFD3_k127_5469016_4 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 0.00000000000000000000000000000000000002441 149.0
HFD3_k127_5469016_5 NMT1-like family K02051 - - 0.0000000003393 72.0
HFD3_k127_5469442_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 441.0
HFD3_k127_5469442_1 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004499 392.0
HFD3_k127_5469442_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006935 271.0
HFD3_k127_5469442_3 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009126 266.0
HFD3_k127_5469442_4 Methylates ribosomal protein L11 K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002924 265.0
HFD3_k127_5469442_5 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000000001 210.0
HFD3_k127_5469442_6 - - - - 0.000000000000000000000000004355 120.0
HFD3_k127_5478984_0 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005758 318.0
HFD3_k127_5478984_1 Glycosyl transferases group 1 K12994 - 2.4.1.349 0.00000000000000000000000000000000000000000000000000000000000000000000002645 255.0
HFD3_k127_5479625_0 - - - - 0.000000000000000000000000000000000000000004278 157.0
HFD3_k127_5479625_1 CsbD-like - - - 0.000000000000000005289 86.0
HFD3_k127_5489199_0 Methyltransferase type 12 - - - 0.000000000000000000000000000000000000000000000000000000000002113 216.0
HFD3_k127_5489607_0 COG0520 Selenocysteine lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 589.0
HFD3_k127_5489607_1 PFAM FAD linked oxidase domain protein K00102,K00104 - 1.1.2.4,1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000971 549.0
HFD3_k127_5489607_10 PFAM FAD linked oxidase domain protein K11472 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001065 277.0
HFD3_k127_5489607_11 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000002801 216.0
HFD3_k127_5489607_13 COG3103 SH3 domain protein K01448 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 0.0002308 53.0
HFD3_k127_5489607_2 PFAM NAD dependent epimerase dehydratase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006683 466.0
HFD3_k127_5489607_3 4Fe-4S dicluster domain K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008286 433.0
HFD3_k127_5489607_4 Domain of unknown function (DUF3390) K18929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003175 330.0
HFD3_k127_5489607_5 ABC-type sugar transport system, permease component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 328.0
HFD3_k127_5489607_6 Binding-protein-dependent transport system inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005738 308.0
HFD3_k127_5489607_7 Bacterial extracellular solute-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 309.0
HFD3_k127_5489607_8 Cysteine-rich domain K18928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005763 284.0
HFD3_k127_5489607_9 Demethylmenaquinone methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003875 276.0
HFD3_k127_5492328_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2.842e-310 972.0
HFD3_k127_5492328_1 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000633 121.0
HFD3_k127_5492328_2 - - - - 0.000000000000000000000000007955 115.0
HFD3_k127_5492328_3 SMART phosphoesterase PHP domain protein - - - 0.000000000000000000000001056 108.0
HFD3_k127_5493819_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004663 463.0
HFD3_k127_5493819_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K13810 - 2.2.1.2,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000006287 225.0
HFD3_k127_5493819_2 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000003169 194.0
HFD3_k127_5493819_3 PFAM NIPSNAP family containing protein - - - 0.000000000000000000000000000000000000000001352 158.0
HFD3_k127_5503631_0 HEAT repeats - - - 0.0000000000000000000000000000000000000000000000000000008826 207.0
HFD3_k127_5503631_1 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.000000000000000000000000005345 111.0
HFD3_k127_5503631_2 Polymer-forming cytoskeletal - - - 0.0000000000000000001111 96.0
HFD3_k127_5503631_3 Putative peptidase family - - - 0.0002429 45.0
HFD3_k127_5508171_0 GGDEF domain' - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 516.0
HFD3_k127_5508171_1 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000617 479.0
HFD3_k127_5508171_2 aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004815 437.0
HFD3_k127_5508171_3 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 429.0
HFD3_k127_5508171_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004489 396.0
HFD3_k127_5508171_5 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 293.0
HFD3_k127_5508171_6 SMART Signal transduction response regulator, receiver region - - - 0.000000000000000000000000000000000000000000000000000000000000001129 221.0
HFD3_k127_5508171_7 protein phosphatase 2C domain protein - - - 0.000000000000000000000000000000000000000001994 179.0
HFD3_k127_5508171_8 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000003924 166.0
HFD3_k127_5508171_9 KaiB K08481 - - 0.00000000000000000000000000000001907 130.0
HFD3_k127_5515317_0 sister chromatid segregation - - - 1.266e-201 635.0
HFD3_k127_5515317_1 - - - - 0.000000000000000000000001822 105.0
HFD3_k127_5515317_2 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000003833 54.0
HFD3_k127_5519454_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835,K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 428.0
HFD3_k127_5519454_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005514 421.0
HFD3_k127_5519454_2 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 349.0
HFD3_k127_5519454_3 - - - - 0.0000000000000000000000000000000000000000000000000000000004677 209.0
HFD3_k127_5519454_4 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000000000000000000000000000000000638 206.0
HFD3_k127_5519454_5 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000003868 143.0
HFD3_k127_5519454_6 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000001427 121.0
HFD3_k127_5519454_7 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000008401 73.0
HFD3_k127_5519454_8 PFAM cell divisionFtsK SpoIIIE K03466 GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0000000001062 64.0
HFD3_k127_5524509_0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K03496 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001094 276.0
HFD3_k127_5524509_1 SMART protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000005866 265.0
HFD3_k127_5524509_2 GDP-mannose mannosyl hydrolase activity K01858,K03207,K03574 - 3.6.1.55,5.5.1.4 0.00000000000000000000000000000000000000000002257 166.0
HFD3_k127_5524509_3 ECF sigma factor K03088 - - 0.00000000000000000000000000000000000001767 153.0
HFD3_k127_5524509_4 PFAM response regulator receiver, regulatory protein LuxR - - - 0.0000000000000000000000000002474 122.0
HFD3_k127_5527491_0 NADPH quinone reductase - - - 0.0000000000000000000000000000000000000000000000000000000002181 205.0
HFD3_k127_5527491_1 glycosyl hydrolase, BNR repeat-containing protein - - - 0.0001685 54.0
HFD3_k127_5537353_0 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 4.917e-280 876.0
HFD3_k127_5537353_1 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003296 387.0
HFD3_k127_5537353_2 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008792 343.0
HFD3_k127_5537353_3 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000001783 183.0
HFD3_k127_5537353_4 Ferric reductase like transmembrane component - - - 0.000000000000000000000000000000004184 139.0
HFD3_k127_5537353_5 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.00000000000000000000000008257 110.0
HFD3_k127_5537353_6 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01190 - 3.2.1.23 0.0000005439 53.0
HFD3_k127_5537362_0 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002445 266.0
HFD3_k127_5537362_1 Participates in transcription elongation, termination and antitermination K02601,K05785 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000221 112.0
HFD3_k127_5537362_2 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.0000000000000000000000002253 109.0
HFD3_k127_5537362_3 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07667 - - 0.0001645 51.0
HFD3_k127_5542484_0 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006155 456.0
HFD3_k127_5542484_1 Protein involved in amylo-alpha-1,6-glucosidase activity and glycogen biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008941 359.0
HFD3_k127_5542484_10 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000002274 81.0
HFD3_k127_5542484_11 Ami_2 - - - 0.000000000001838 80.0
HFD3_k127_5542484_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 378.0
HFD3_k127_5542484_3 cellulase activity K01183 - 3.2.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 302.0
HFD3_k127_5542484_4 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000649 251.0
HFD3_k127_5542484_5 Domain of unknown function (DUF4118) - - - 0.000000000000000000000000000000000000000000000000000002486 221.0
HFD3_k127_5542484_6 Histidine kinase K07675 - 2.7.13.3 0.0000000000000000000000000000000000000000005722 183.0
HFD3_k127_5542484_7 response regulator K02282,K07705 - - 0.000000000000000000000000004346 115.0
HFD3_k127_5542484_8 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000001243 109.0
HFD3_k127_5542484_9 Transglycosylase associated protein - - - 0.000000000000000001951 87.0
HFD3_k127_5554190_0 PFAM ABC transporter related K02056 - 3.6.3.17 1.901e-196 627.0
HFD3_k127_5554190_1 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 344.0
HFD3_k127_5554190_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 311.0
HFD3_k127_5554190_3 PFAM basic membrane lipoprotein K07335 - - 0.00000000000000000000000000000000000000000000000000000000000000000008768 240.0
HFD3_k127_5554190_4 Ferric uptake regulator family K03711 - - 0.0000000000000000000000000000813 123.0
HFD3_k127_5554765_0 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000001625 198.0
HFD3_k127_5554765_1 PFAM glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000001842 154.0
HFD3_k127_5554765_2 - - - - 0.0000000000000008635 87.0
HFD3_k127_5564881_0 - K07138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007661 539.0
HFD3_k127_5564881_1 PFAM metallophosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005796 318.0
HFD3_k127_5565353_0 system Galactitol-specific IIC component K02775 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006627 474.0
HFD3_k127_5565353_1 Carboxymuconolactone decarboxylase family K07486 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 290.0
HFD3_k127_5565353_2 DeoR C terminal sensor domain K02081,K02444,K03436 - - 0.0000000000000000000000000000000000000000000000000000007894 201.0
HFD3_k127_5565353_3 methyltransferase activity - - - 0.0000000000000000000000000000000000001952 148.0
HFD3_k127_5565353_4 transcriptional regulator - - - 0.000000000000000000002511 96.0
HFD3_k127_5565353_5 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000003456 54.0
HFD3_k127_5566809_0 Voltage gated chloride channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 609.0
HFD3_k127_5566809_1 V-type ATPase 116kDa subunit family K02123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 299.0
HFD3_k127_5574730_0 PFAM Glycosyl transferase family 2 K20534 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004693 435.0
HFD3_k127_5574730_1 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 350.0
HFD3_k127_5574730_2 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000605 340.0
HFD3_k127_5574730_3 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000002421 180.0
HFD3_k127_5574730_4 TIGRFAM galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.00000000000000000000000008787 109.0
HFD3_k127_5580280_0 Flavin containing amine oxidoreductase K01854 - 5.4.99.9 1.357e-196 623.0
HFD3_k127_5580280_1 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000001254 116.0
HFD3_k127_5580280_2 asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.0000000000001162 72.0
HFD3_k127_5580280_3 PFAM Na-Ca exchanger integrin-beta4 - - - 0.000008095 54.0
HFD3_k127_5587645_0 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000002067 211.0
HFD3_k127_5587645_1 Glycosyl transferase, family 2 K07011 - - 0.000000000000000000000000000000000000000000000000000001173 203.0
HFD3_k127_5587645_2 Glycosyl transferase family 21 K11936 - - 0.000000000000000000000000000000000000000001622 173.0
HFD3_k127_5587645_3 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000002332 67.0
HFD3_k127_5588451_0 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006059 331.0
HFD3_k127_5588451_1 Enoyl-(Acyl carrier protein) reductase K00059,K07535 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008742 288.0
HFD3_k127_5588451_2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001567 279.0
HFD3_k127_5588451_3 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000004823 230.0
HFD3_k127_5588451_4 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000001904 65.0
HFD3_k127_5588451_5 - - - - 0.000001435 54.0
HFD3_k127_5606232_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004756 564.0
HFD3_k127_5606232_1 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005798 419.0
HFD3_k127_5606232_2 Family of unknown function (DUF1028) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 350.0
HFD3_k127_5606232_3 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008546 329.0
HFD3_k127_5606232_4 Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002148 252.0
HFD3_k127_5606232_5 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000003918 213.0
HFD3_k127_5606232_6 Lysin motif - - - 0.0000000000000000000000000000000000000000000000004574 191.0
HFD3_k127_5606232_7 Patatin-like phospholipase - - - 0.000000000000000000000009093 115.0
HFD3_k127_5606232_8 methyltransferase activity - - - 0.0000000000000002009 84.0
HFD3_k127_5615510_0 dihydrofolate reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 331.0
HFD3_k127_5615510_1 PFAM Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000003144 236.0
HFD3_k127_5620835_0 Gamma-glutamyltranspeptidase 2-like K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003269 528.0
HFD3_k127_5620835_1 PFAM aminoglycoside phosphotransferase K18844 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 332.0
HFD3_k127_5620835_2 - - - - 0.0000000000000000000000000000000000000000000000000000005929 200.0
HFD3_k127_5620835_3 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000005449 195.0
HFD3_k127_5620835_4 - - - - 0.0000000000000000000000000000000000000000000000000002701 191.0
HFD3_k127_5625499_0 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004574 399.0
HFD3_k127_5625499_1 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003751 310.0
HFD3_k127_5625499_2 pfam abc K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003696 295.0
HFD3_k127_5625499_3 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000002294 96.0
HFD3_k127_5626544_0 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004784 571.0
HFD3_k127_5626544_1 Histidine kinase K07646 - 2.7.13.3 0.0000000000000000000000000000000000000006102 155.0
HFD3_k127_5642417_0 PFAM NAD-dependent epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 474.0
HFD3_k127_5642417_1 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 471.0
HFD3_k127_5642417_10 Cupin 2, conserved barrel domain protein - - - 0.0000003789 51.0
HFD3_k127_5642417_2 PFAM penicillin-binding protein transpeptidase K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004345 359.0
HFD3_k127_5642417_3 PFAM O-antigen polymerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000597 336.0
HFD3_k127_5642417_4 -O-antigen K05350,K21000 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 347.0
HFD3_k127_5642417_5 pathogenesis K21471,K21687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004496 270.0
HFD3_k127_5642417_6 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000001952 167.0
HFD3_k127_5642417_7 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000003751 132.0
HFD3_k127_5642417_8 GtrA-like protein - - - 0.0000000000000000000000000007335 119.0
HFD3_k127_5642417_9 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins K03571 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - 0.00000000000000000768 89.0
HFD3_k127_5648939_0 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001092 273.0
HFD3_k127_5648939_1 naringenin-chalcone synthase K16167 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002098 257.0
HFD3_k127_5648939_2 PFAM response regulator receiver K07658 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001275 245.0
HFD3_k127_5648939_3 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000006426 242.0
HFD3_k127_5648939_4 Transcriptional regulator PadR-like family - - - 0.000000000000000000002146 97.0
HFD3_k127_5648939_5 resistance protein TehB - - - 0.0000000000007849 75.0
HFD3_k127_5648939_6 - - - - 0.0009559 51.0
HFD3_k127_5660106_0 membrane - - - 0.0000000000000000000000000000000000139 145.0
HFD3_k127_5660106_1 PFAM 6-O-methylguanine DNA methyltransferase, DNA binding domain K07443 - - 0.0000000000000000000000002866 109.0
HFD3_k127_5660106_2 Psort location CytoplasmicMembrane, score - - - 0.00000001082 59.0
HFD3_k127_5664070_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 599.0
HFD3_k127_5664070_1 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009931 283.0
HFD3_k127_5665815_0 Aldo/keto reductase family K05882 - 1.1.1.91 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005724 500.0
HFD3_k127_5665815_1 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 448.0
HFD3_k127_5665815_2 transferase activity, transferring glycosyl groups K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000056 301.0
HFD3_k127_5665815_3 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000005946 237.0
HFD3_k127_5665815_4 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000001043 123.0
HFD3_k127_5665815_5 Redoxin - - - 0.00002191 47.0
HFD3_k127_5669097_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 354.0
HFD3_k127_5669097_1 PFAM 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000002446 168.0
HFD3_k127_5669097_2 Polysulphide reductase, NrfD - - - 0.00000294 51.0
HFD3_k127_5671007_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006534 492.0
HFD3_k127_5671007_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000956 277.0
HFD3_k127_5671007_2 Peptidase M28 - - - 0.00000000000000000000000001284 109.0
HFD3_k127_5671007_3 Cytochrome C and Quinol oxidase polypeptide I K07234 - - 0.00000000000000000000006164 101.0
HFD3_k127_5678720_0 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003129 252.0
HFD3_k127_5678720_1 response regulator, receiver K02479 - - 0.00000000000000000000000000000000000000000000000000000000000000001415 230.0
HFD3_k127_5678720_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000003175 214.0
HFD3_k127_5692785_0 PFAM basic membrane lipoprotein K07335 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003315 294.0
HFD3_k127_5692785_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000004733 227.0
HFD3_k127_5692785_2 Membrane transport protein K07088 - - 0.0000000000000000000000000000000000000000000000000007081 195.0
HFD3_k127_5692785_3 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 0.0000000000000000000000000000007996 124.0
HFD3_k127_5692785_4 Jacalin-like lectin domain - - - 0.000000000000000000001184 108.0
HFD3_k127_5703350_0 PFAM peptidase M3A and M3B, thimet oligopeptidase F K08602 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 435.0
HFD3_k127_5703350_1 dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000000000002558 132.0
HFD3_k127_5720805_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006767 393.0
HFD3_k127_5720805_1 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003292 332.0
HFD3_k127_5720805_2 NAD-dependent epimerase dehydratase K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 310.0
HFD3_k127_5720805_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 301.0
HFD3_k127_5720805_4 mevalonate kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001494 244.0
HFD3_k127_5720805_5 PFAM regulatory protein, MerR K22491 - - 0.000000000000000000000000000000000000000000000000105 195.0
HFD3_k127_5720805_6 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000002946 160.0
HFD3_k127_5720805_7 COG COG1073 Hydrolases of the alpha beta superfamily - - - 0.000000000000004509 76.0
HFD3_k127_5722828_0 ABC transporter K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005107 554.0
HFD3_k127_5722828_1 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003315 421.0
HFD3_k127_5722828_2 ABC transporter substrate-binding protein PnrA-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001037 278.0
HFD3_k127_5722828_3 CO dehydrogenase flavoprotein C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002508 254.0
HFD3_k127_5726728_0 Domain of unknown function (DUF1998) K06877 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007426 314.0
HFD3_k127_5726728_1 LysE type translocator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005587 263.0
HFD3_k127_5726728_2 cellulose binding - - - 0.00000000000000000000000000000000000000006315 163.0
HFD3_k127_5726728_3 Major Facilitator Superfamily K08223 - - 0.00000000000000000000000000000002607 135.0
HFD3_k127_5727913_0 Pyridoxal-dependent decarboxylase conserved domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 389.0
HFD3_k127_5727913_1 phosphate transporter K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 317.0
HFD3_k127_5727913_2 Protein of unknown function DUF89 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 311.0
HFD3_k127_5727913_3 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000007625 221.0
HFD3_k127_5727913_4 Secreted repeat of unknown function - - - 0.000000000000000000000000007118 124.0
HFD3_k127_5727913_5 Cupredoxin-like domain - - - 0.00000000001041 72.0
HFD3_k127_5739089_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 1.026e-251 794.0
HFD3_k127_5739089_1 CHAD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000119 292.0
HFD3_k127_5739089_2 SPFH Band 7 PHB domain protein - - - 0.00000000000000000000000000000000000000000000004684 183.0
HFD3_k127_5739089_3 - - - - 0.000000000000000000000000000000000003672 146.0
HFD3_k127_5739089_4 VIT family - - - 0.0000000000000002905 79.0
HFD3_k127_5739089_5 phosphohistidine phosphatase, SixA K08296 - - 0.00073 44.0
HFD3_k127_5739964_0 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003848 254.0
HFD3_k127_5739964_1 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000002849 240.0
HFD3_k127_5739964_2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.000000000000000000000000000000000003171 138.0
HFD3_k127_5752980_0 Belongs to the ABC transporter superfamily K02031,K02032 - - 1.149e-274 861.0
HFD3_k127_5752980_1 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 1.628e-204 644.0
HFD3_k127_5752980_2 CoA-transferase family III K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 569.0
HFD3_k127_5752980_3 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 350.0
HFD3_k127_5752980_4 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000608 315.0
HFD3_k127_5771132_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2.5e-251 790.0
HFD3_k127_5790160_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007544 565.0
HFD3_k127_5790160_1 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 376.0
HFD3_k127_5790160_2 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.0000000000000000000000000000000000000000371 172.0
HFD3_k127_5790160_3 N-4 methylation of cytosine K00590 - 2.1.1.113 0.0000000000000000003417 102.0
HFD3_k127_5790160_4 Tetratricopeptide repeat - - - 0.0000000001825 68.0
HFD3_k127_5802972_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008044 471.0
HFD3_k127_5802972_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 337.0
HFD3_k127_5803006_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004896 474.0
HFD3_k127_5803006_1 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 - - 0.000000000000000000001708 106.0
HFD3_k127_5824985_0 AMP-binding enzyme C-terminal domain K08295 - 6.2.1.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 409.0
HFD3_k127_5824985_1 Coenzyme A transferase K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006793 346.0
HFD3_k127_5824985_2 amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001177 266.0
HFD3_k127_5824985_3 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.000000000000000000000000002168 112.0
HFD3_k127_5842143_0 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000007249 235.0
HFD3_k127_5842143_1 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.00000000000000000000000000000000001113 145.0
HFD3_k127_5842143_2 TIGRFAM geranylgeranyl reductase K10960 - 1.3.1.111,1.3.1.83 0.0000000000000000000000000002377 121.0
HFD3_k127_5842143_3 PFAM sigma-70 region 2 domain protein K03088 - - 0.00000000000000000000000008521 113.0
HFD3_k127_5842301_0 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005853 606.0
HFD3_k127_5842301_1 FMN-dependent dehydrogenase K01823 GO:0003674,GO:0003824,GO:0004452,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0071704,GO:1901576 5.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 379.0
HFD3_k127_5842301_2 Involved in the biosynthesis of porphyrin-containing compound - GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 363.0
HFD3_k127_5842301_3 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 306.0
HFD3_k127_5842301_4 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 305.0
HFD3_k127_5842301_5 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004958 287.0
HFD3_k127_5842301_6 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000000000008989 171.0
HFD3_k127_5842301_7 histone H2A-K13 ubiquitination K01338,K07157 - 3.4.21.53 0.00000000000000000000000000000000000661 146.0
HFD3_k127_5842301_8 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000000000000000000000009721 108.0
HFD3_k127_5844045_0 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 372.0
HFD3_k127_5844045_1 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002118 265.0
HFD3_k127_5846330_0 ABC transporter substrate-binding protein family 5 K02035,K15580 - - 1.534e-198 634.0
HFD3_k127_5846330_1 Amidohydrolase family K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007566 537.0
HFD3_k127_5846330_2 protein contain chitin-binding domain type 3 K01183,K21606 - 3.2.1.14,3.2.1.202 0.00000006689 60.0
HFD3_k127_5858371_0 helix_turn_helix, Lux Regulon K02282,K07689 - - 0.000000000000000000000000000000000000000000000000000000000000006862 222.0
HFD3_k127_5858371_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000001765 203.0
HFD3_k127_5858371_2 GAF domain - - - 0.0000000000000000000000000000000005811 145.0
HFD3_k127_5858371_3 response regulator K02282,K07705 - - 0.00000000000000000000000000001617 121.0
HFD3_k127_5863601_0 oligoendopeptidase F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 298.0
HFD3_k127_5863601_1 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000000000006589 201.0
HFD3_k127_5863601_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000116 100.0
HFD3_k127_58657_0 Anaerobic dimethyl sulfoxide reductase, A subunit, DmsA YnfE K07306 - 1.8.5.3 4.156e-209 672.0
HFD3_k127_58657_1 PFAM serine dehydratase alpha chain K01752 - 4.3.1.17 0.0000005513 51.0
HFD3_k127_5883750_0 PFAM phosphoesterase, RecJ domain protein K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 481.0
HFD3_k127_5883750_1 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005284 475.0
HFD3_k127_5883750_10 alginic acid biosynthetic process - - - 0.000000000000000000003156 106.0
HFD3_k127_5883750_11 Lysin motif - - - 0.00000001863 64.0
HFD3_k127_5883750_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 394.0
HFD3_k127_5883750_3 Penicillin-binding Protein dimerisation domain K03587,K08384 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000457 374.0
HFD3_k127_5883750_4 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008047 322.0
HFD3_k127_5883750_5 NUDIX domain K01515,K03574 - 3.6.1.13,3.6.1.55 0.00000000000000000000000000000000000003271 148.0
HFD3_k127_5883750_6 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000003241 146.0
HFD3_k127_5883750_7 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000000000003584 145.0
HFD3_k127_5883750_8 Zn-ribbon protein possibly nucleic acid-binding K07164 - - 0.000000000000000000000000000689 121.0
HFD3_k127_5883750_9 Belongs to the UPF0235 family K09131 - - 0.0000000000000000000001166 102.0
HFD3_k127_5889567_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 511.0
HFD3_k127_5889567_1 Haloacid dehalogenase-like hydrolase K20866 - 3.1.3.10 0.0000000000000000000000000000000000000000000000000006402 192.0
HFD3_k127_5889567_2 PFAM Xylose isomerase domain protein TIM barrel - - - 0.00000000000000000000000000000000000000275 158.0
HFD3_k127_5889567_3 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.000000000004365 66.0
HFD3_k127_5889567_4 Haloacid dehalogenase-like hydrolase - - - 0.0000000008015 68.0
HFD3_k127_5908143_0 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009524 490.0
HFD3_k127_5908143_1 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000002332 233.0
HFD3_k127_5908143_2 calcium- and calmodulin-responsive adenylate cyclase activity K07260 - 3.4.17.14 0.000000000000000000000000000000000000000000000000000000885 205.0
HFD3_k127_5908143_3 PFAM Pentapeptide repeats (8 copies) - - - 0.0000000000000000000000000004672 119.0
HFD3_k127_5929512_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 1.574e-214 687.0
HFD3_k127_5929512_1 Baseplate J-like protein K01218 - 3.2.1.78 0.00001025 54.0
HFD3_k127_5946548_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005943 302.0
HFD3_k127_5946548_1 Chromatin associated protein KTI12 - - - 0.0000000000000000001258 96.0
HFD3_k127_5946548_2 domain protein - - - 0.00004131 49.0
HFD3_k127_5976016_0 Amidohydrolase family K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 441.0
HFD3_k127_5976016_1 Alcohol dehydrogenase zinc-binding domain protein K13953,K18382 - 1.1.1.1 0.000000000000000000000000000000000000000000000000001959 192.0
HFD3_k127_5982044_0 PFAM binding-protein-dependent transport systems inner membrane component K15771 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007072 403.0
HFD3_k127_5982044_1 PFAM extracellular solute-binding protein family 1 K15770 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 376.0
HFD3_k127_5982044_10 Domain of unknown function (DUF4870) - - - 0.00005327 53.0
HFD3_k127_5982044_2 PFAM binding-protein-dependent transport systems inner membrane component K15772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 364.0
HFD3_k127_5982044_3 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001073 264.0
HFD3_k127_5982044_4 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000002775 249.0
HFD3_k127_5982044_5 alpha-amylase K01176,K01187 - 3.2.1.1,3.2.1.20 0.000000000000000000000000000000000000000000000000000000000001855 222.0
HFD3_k127_5982044_6 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000000000002274 168.0
HFD3_k127_5982044_7 Protein of unknown function (DUF4013) - - - 0.00000000000000000000000000000004859 134.0
HFD3_k127_5982044_8 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000000006986 125.0
HFD3_k127_5982044_9 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000004084 119.0
HFD3_k127_598703_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003831 410.0
HFD3_k127_598703_1 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000001921 262.0
HFD3_k127_598703_2 Histidine kinase K07680,K07778,K11617,K14988 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000002372 250.0
HFD3_k127_6003831_0 TIGRFAM threonine synthase K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 464.0
HFD3_k127_6003831_1 Amino acid kinase family K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000001162 265.0
HFD3_k127_6003831_2 PFAM Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000001194 156.0
HFD3_k127_6003831_3 COG0457 FOG TPR repeat - - - 0.00005191 55.0
HFD3_k127_6018613_0 carbohydrate binding K00702 - 2.4.1.20 0.0 1224.0
HFD3_k127_6026411_0 Pyridoxal-phosphate dependent enzyme K01697,K01738 - 2.5.1.47,4.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 540.0
HFD3_k127_6026411_1 PFAM cytochrome c biogenesis protein, transmembrane region - - - 0.0000000000000000000000000000000141 137.0
HFD3_k127_6026411_2 heme binding - - - 0.0000000000000000000000000000453 130.0
HFD3_k127_6026411_3 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000005124 101.0
HFD3_k127_6026411_4 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain - - - 0.00000006964 54.0
HFD3_k127_6026411_6 Rhodanese Homology Domain - - - 0.0002299 47.0
HFD3_k127_6083335_0 Heterodisulfide reductase, subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006246 601.0
HFD3_k127_6083335_1 4fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 473.0
HFD3_k127_6083335_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001824 229.0
HFD3_k127_6083335_3 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000001168 197.0
HFD3_k127_6083335_4 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000362 84.0
HFD3_k127_6091895_0 ATPase associated with various cellular activities, AAA_3 K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 402.0
HFD3_k127_6091895_1 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001984 285.0
HFD3_k127_6091895_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000002818 69.0
HFD3_k127_6091895_3 protein serine/threonine phosphatase activity - - - 0.000000000267 74.0
HFD3_k127_6146233_0 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009757 327.0
HFD3_k127_6146233_1 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000002914 121.0
HFD3_k127_6146233_2 - - - - 0.00005706 49.0
HFD3_k127_6165246_0 PFAM Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000004792 174.0
HFD3_k127_6165246_1 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000008858 126.0
HFD3_k127_6165246_2 Glycosyltransferase like family 2 - - - 0.00000000000000000000008086 109.0
HFD3_k127_6165246_3 PFAM Glycosyl hydrolases family 16 - - - 0.000000000004038 72.0
HFD3_k127_619337_0 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 448.0
HFD3_k127_619337_1 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000000000000000000000000000001056 223.0
HFD3_k127_6203537_0 TAP-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 320.0
HFD3_k127_6203537_1 CAAX protease self-immunity - - - 0.00000003851 60.0
HFD3_k127_6213964_0 Saccharopine dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 316.0
HFD3_k127_6213964_1 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000047 85.0
HFD3_k127_6219792_0 peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 578.0
HFD3_k127_6219792_1 CAAX protease self-immunity - - - 0.00000000000000000000000000000000000000000000000000000000000002049 225.0
HFD3_k127_6219792_2 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000004417 226.0
HFD3_k127_6219792_3 COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes - - - 0.00000000000000000000001813 106.0
HFD3_k127_6219792_4 - - - - 0.0000315 50.0
HFD3_k127_6221826_0 PFAM IstB domain protein ATP-binding protein - - - 0.000000000000000000000000000000000000000000000000003153 186.0
HFD3_k127_6221826_1 PFAM Response regulator receiver domain - - - 0.0000000000000000000000000007611 119.0
HFD3_k127_6221826_2 - - - - 0.0000229 48.0
HFD3_k127_6221826_3 sequence-specific DNA binding - - - 0.00004346 49.0
HFD3_k127_6225052_0 nitrogen compound transport K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 382.0
HFD3_k127_6225052_1 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 340.0
HFD3_k127_6225052_2 ABC transporter substrate-binding protein family 5 K02035,K15580 - - 0.0000000000000000000000000000000000000000000000000000000002503 205.0
HFD3_k127_6225052_3 Glycosyltransferase family 28 N-terminal domain - - - 0.000000000000000000000000000007288 122.0
HFD3_k127_6225052_4 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.000000000002004 72.0
HFD3_k127_6229576_0 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 405.0
HFD3_k127_6229576_1 Binding-protein-dependent transport system inner membrane component K17319 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 387.0
HFD3_k127_6229576_2 Binding-protein-dependent transport system inner membrane component K17320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 295.0
HFD3_k127_6229576_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000002679 119.0
HFD3_k127_6233617_0 Branched-chain amino acid transport system / permease component K01997,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 376.0
HFD3_k127_6233617_1 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 298.0
HFD3_k127_6233617_2 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003297 297.0
HFD3_k127_6233617_3 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 294.0
HFD3_k127_6233617_4 Cysteine-rich domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001541 265.0
HFD3_k127_6235086_0 Alpha amylase, C-terminal all-beta domain K00700 - 2.4.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 449.0
HFD3_k127_6235086_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 437.0
HFD3_k127_6235086_10 HxlR-like helix-turn-helix - - - 0.000000000000000000000005786 105.0
HFD3_k127_6235086_11 Cupin 2, conserved barrel domain protein - - - 0.00000000002355 71.0
HFD3_k127_6235086_2 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 367.0
HFD3_k127_6235086_3 Creatinase/Prolidase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005087 334.0
HFD3_k127_6235086_4 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006452 308.0
HFD3_k127_6235086_5 Belongs to the peptidase M24B family K01271 - 3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 297.0
HFD3_k127_6235086_6 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004042 277.0
HFD3_k127_6235086_7 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000000003762 206.0
HFD3_k127_6235086_8 Cupin domain - - - 0.00000000000000000000000000000000000000000000003201 175.0
HFD3_k127_6235086_9 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000007674 123.0
HFD3_k127_6237375_0 exo-alpha-(2->6)-sialidase activity - - - 2.36e-203 649.0
HFD3_k127_6237375_1 Belongs to the peptidase S8 family K08651,K14645 - 3.4.21.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 610.0
HFD3_k127_6237375_10 May be involved in the transport of PQQ or its precursor to the periplasm - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006008 260.0
HFD3_k127_6237375_11 DNA-binding transcription factor activity K03892 - - 0.000000000000000000000000002974 113.0
HFD3_k127_6237375_12 COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases K03641 - - 0.000000000000000000006073 107.0
HFD3_k127_6237375_13 Bacterial Ig-like domain (group 3) K20276 - - 0.000000000000000001636 101.0
HFD3_k127_6237375_14 luxR family - - - 0.0000006295 55.0
HFD3_k127_6237375_15 PFAM Response regulator receiver domain - - - 0.000001312 55.0
HFD3_k127_6237375_2 bacterial-type flagellum-dependent cell motility - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006732 379.0
HFD3_k127_6237375_3 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 338.0
HFD3_k127_6237375_4 Methionine aminopeptidase K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004079 304.0
HFD3_k127_6237375_5 GHKL domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000457 317.0
HFD3_k127_6237375_6 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009276 303.0
HFD3_k127_6237375_7 PFAM CBS domain containing protein K04767 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000276 270.0
HFD3_k127_6237375_8 Methyltransferase type 11 K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000001823 250.0
HFD3_k127_6237375_9 NADPH quinone reductase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000001861 248.0
HFD3_k127_6238129_0 tRNA synthetase, class II (D, K and N) K01893 - 6.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001477 287.0
HFD3_k127_6238129_1 ADP binding - - - 0.00000000000002125 85.0
HFD3_k127_6239702_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004369 310.0
HFD3_k127_6239702_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000000000000000000003689 213.0
HFD3_k127_6239702_2 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000001159 101.0
HFD3_k127_6240588_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 535.0
HFD3_k127_6240588_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007967 432.0
HFD3_k127_6240588_2 tripeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000004872 209.0
HFD3_k127_6240588_3 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K21142 - 2.8.1.12 0.0000000000000000000000000000000000000000000000000000142 199.0
HFD3_k127_6240588_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K05580 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000001945 188.0
HFD3_k127_6240764_0 Polysaccharide biosynthesis protein - - - 3.731e-296 956.0
HFD3_k127_6240764_1 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000003801 265.0
HFD3_k127_6240764_2 Glycosyl transferase, WecB TagA CpsF family K05946 - 2.4.1.187 0.00000000000000000000000000000000000000000000000000000000000000000007982 238.0
HFD3_k127_6240764_3 Transcriptional regulatory protein, C terminal K02483 - - 0.00000000000000000000000000000000000001723 152.0
HFD3_k127_6240764_4 PFAM RNP-1 like RNA-binding protein - - - 0.00000000000000000000000004401 112.0
HFD3_k127_6240764_5 Periplasmic copper-binding protein (NosD) - - - 0.000000000000000007499 94.0
HFD3_k127_6240764_6 Domain of unknown function (DUF1992) K19373 - - 0.0000000000000004392 85.0
HFD3_k127_6240764_7 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.000000002415 60.0
HFD3_k127_6246186_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1028.0
HFD3_k127_6246186_1 Leucine carboxyl methyltransferase - - - 0.0000000000000000000000000000000000001512 147.0
HFD3_k127_6250030_0 PFAM peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004906 383.0
HFD3_k127_6250030_1 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000003741 205.0
HFD3_k127_6250030_2 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000000000002484 183.0
HFD3_k127_6250030_3 regulator of chromosome condensation, RCC1 - - - 0.0000000000000000000000000000000000000000000001189 196.0
HFD3_k127_6250030_4 sigma-70 region 2 domain protein K03088 - - 0.0000000000000000000000000000000000001329 149.0
HFD3_k127_6250030_5 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000391 105.0
HFD3_k127_6250030_6 Domain of Unknown Function (DUF1080) - - - 0.000000000003833 81.0
HFD3_k127_6250030_7 metal-dependent membrane protease - - - 0.0000001153 62.0
HFD3_k127_6250311_0 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 417.0
HFD3_k127_6250311_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004414 286.0
HFD3_k127_6250311_2 TIGRFAM zinc-binding alcohol dehydrogenase family protein K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000003259 245.0
HFD3_k127_6250311_3 Creatinase/Prolidase N-terminal domain K01271 - 3.4.13.9 0.000000000000000000000000000000000000000000000000000004574 206.0
HFD3_k127_6251353_0 Glucuronate isomerase K01812 - 5.3.1.12 6.932e-220 690.0
HFD3_k127_6251353_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III - - - 0.00000000000000000000000000000000000000000008917 166.0
HFD3_k127_6251572_0 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 374.0
HFD3_k127_6251572_1 N-terminal TM domain of oligopeptide transport permease C K15582 - - 0.000000000000000000000000000000000000000000000000000000000000000000004149 238.0
HFD3_k127_6251819_0 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004165 444.0
HFD3_k127_6251819_1 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000001059 153.0
HFD3_k127_6251819_2 Chitinase class I K03791 - - 0.00000000000000000001188 100.0
HFD3_k127_6251819_3 COG0639 Diadenosine tetraphosphatase and related - - - 0.00000000003861 64.0
HFD3_k127_6255319_0 Gaf domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009535 264.0
HFD3_k127_6255319_1 Diguanylate cyclase - - - 0.0000000000000000000000000000000000002808 162.0
HFD3_k127_6256033_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 571.0
HFD3_k127_6256033_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008113 272.0
HFD3_k127_6256033_2 Protein of unknown function (DUF2442) - - - 0.00000000000000000000000000000003709 128.0
HFD3_k127_6256033_3 Domain of unknown function (DUF4160) - - - 0.0000000003294 63.0
HFD3_k127_6263347_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0 1098.0
HFD3_k127_6263347_1 CoA-ligase K02381 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 606.0
HFD3_k127_6263347_2 Protein of unknown function (DUF1116) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005512 578.0
HFD3_k127_6263347_3 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 490.0
HFD3_k127_6263347_4 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 388.0
HFD3_k127_6263347_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009962 314.0
HFD3_k127_6263347_6 CO dehydrogenase flavoprotein domain protein K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003173 294.0
HFD3_k127_6263347_7 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000001161 258.0
HFD3_k127_6266834_0 PFAM sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 424.0
HFD3_k127_6266834_1 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 411.0
HFD3_k127_6266834_2 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005152 395.0
HFD3_k127_6266834_3 PFAM lipopolysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008672 322.0
HFD3_k127_6266834_4 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000001367 124.0
HFD3_k127_6266834_5 Involved in the TonB-independent uptake of proteins K03641 - - 0.00000000118 71.0
HFD3_k127_6275450_0 AAA ATPase domain - - - 5.302e-263 828.0
HFD3_k127_6275450_1 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 413.0
HFD3_k127_6275450_2 cell redox homeostasis K02199 - - 0.0000000000000000000000000000000000000000000152 173.0
HFD3_k127_6275450_3 light absorption - - - 0.00000000000000000000000000000000000000000001999 165.0
HFD3_k127_6275450_5 creatininase K01470 - 3.5.2.10 0.00000000000001593 75.0
HFD3_k127_6279080_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 372.0
HFD3_k127_6279080_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004287 296.0
HFD3_k127_6279080_2 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001683 265.0
HFD3_k127_6279080_3 Rubredoxin-type Fe(Cys)4 protein - - - 0.00000000000000000000000000000000000000000000000000000004458 200.0
HFD3_k127_6279080_4 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 GO:0000166,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0009987,GO:0015036,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0016667,GO:0016668,GO:0019725,GO:0019899,GO:0032991,GO:0035375,GO:0036094,GO:0040007,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0045454,GO:0048037,GO:0050660,GO:0050662,GO:0050789,GO:0050794,GO:0051287,GO:0055114,GO:0065007,GO:0065008,GO:0070404,GO:0071944,GO:0097159,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.8.1.4 0.00000000000000000000000000000000000000000000000003658 186.0
HFD3_k127_6289255_0 PFAM multicopper oxidase type 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002636 617.0
HFD3_k127_6289255_1 DNA binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 451.0
HFD3_k127_6289255_2 PFAM extracellular solute-binding protein family 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003299 402.0
HFD3_k127_6289255_3 glycerophosphodiester transmembrane transport K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004913 353.0
HFD3_k127_6289255_4 Periplasmic binding protein LacI transcriptional regulator K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 306.0
HFD3_k127_6289255_5 transmembrane transport K02025,K05814,K10118,K10237,K10241,K15771,K17235,K17242,K17316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001419 287.0
HFD3_k127_6289255_6 PFAM transglutaminase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000007667 256.0
HFD3_k127_6289255_7 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000002534 219.0
HFD3_k127_6289255_8 ATPases associated with a variety of cellular activities K10112,K10195 - - 0.0000000000000004715 78.0
HFD3_k127_628946_0 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002465 329.0
HFD3_k127_628946_1 imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000008748 232.0
HFD3_k127_628946_2 protein possibly involved in aromatic compounds catabolism - - - 0.00000000000000000000000000000000001096 138.0
HFD3_k127_6289592_0 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 7.596e-257 805.0
HFD3_k127_6289592_1 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003783 514.0
HFD3_k127_6289592_2 AMP-binding enzyme K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 453.0
HFD3_k127_6289592_3 PFAM Pyruvate phosphate dikinase, PEP K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 384.0
HFD3_k127_6289592_4 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K04105,K04110 - 6.2.1.25,6.2.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 325.0
HFD3_k127_6289592_5 Psort location Cytoplasmic, score 8.87 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002819 286.0
HFD3_k127_6289592_6 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000005943 248.0
HFD3_k127_6289592_7 NUDIX domain - - - 0.00000000000000000000000000000000000000139 154.0
HFD3_k127_6289592_8 Histidine phosphatase superfamily (branch 1) - - - 0.0000000000000000002911 98.0
HFD3_k127_6289592_9 SnoaL-like domain - - - 0.000224 48.0
HFD3_k127_6296846_0 ATP-dependent DNA helicase K03657 - 3.6.4.12 3.667e-204 660.0
HFD3_k127_6296846_1 phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000000000002226 246.0
HFD3_k127_6296846_2 PFAM Maf family protein K06287 - - 0.0000000000000000000000000000000000000000002568 166.0
HFD3_k127_6296846_3 Tetratricopeptide repeat - - - 0.0001407 53.0
HFD3_k127_6296911_0 Peptidase MA superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000007928 234.0
HFD3_k127_6296911_1 PFAM peptidase M22 glycoprotease K14742 - - 0.00000000000000000000000000000000000000000000004219 178.0
HFD3_k127_6296911_2 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789,K14742 - 2.3.1.128 0.000000000000000000000000000000000000000000001292 172.0
HFD3_k127_6296911_3 integral membrane protein - - - 0.000000000000000000006397 98.0
HFD3_k127_6296911_4 tetraacyldisaccharide 4'-kinase activity K09791 - - 0.00000000000000002037 86.0
HFD3_k127_6296911_5 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.00000000000000002863 85.0
HFD3_k127_6301076_0 PFAM extracellular solute-binding protein family 1 K02055 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 569.0
HFD3_k127_6301076_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 447.0
HFD3_k127_6301076_2 PFAM binding-protein-dependent transport systems inner membrane component K02054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 395.0
HFD3_k127_6301076_3 Domain of unknown function (DUF4445) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000451 342.0
HFD3_k127_6301076_4 PFAM binding-protein-dependent transport systems inner membrane component K02053 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 344.0
HFD3_k127_6301076_5 Homocysteine S-methyltransferase K00544 - 2.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000006953 253.0
HFD3_k127_6301076_6 Uroporphyrinogen decarboxylase (URO-D) K14080 - 2.1.1.246 0.00000000000000000000000000000000000000000000000000000000000000000000002452 253.0
HFD3_k127_6301076_7 haloacid dehalogenase-like hydrolase K22292 - 3.1.3.105 0.0002451 48.0
HFD3_k127_6301245_0 transferase activity, transferring glycosyl groups K09118,K13693,K21349 - 2.4.1.266,2.4.1.268 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 511.0
HFD3_k127_6301245_1 Glycosyltransferase Family 4 K21369 - 2.4.1.270 0.00000000008473 64.0
HFD3_k127_6301245_2 Required for morphogenesis under gluconeogenic growth conditions - - - 0.00000000263 61.0
HFD3_k127_6301655_0 Domain of unknown function (DUF4162) K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005286 282.0
HFD3_k127_6301655_1 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000002676 251.0
HFD3_k127_6301655_2 PFAM sigma-70 region 2 domain protein K03088 - - 0.0000000000000000000000000000000000000000000008835 171.0
HFD3_k127_6301655_3 - - - - 0.000000000000000000003896 105.0
HFD3_k127_6301655_4 Polymer-forming cytoskeletal - - - 0.0000000000000003616 90.0
HFD3_k127_6311418_0 Major facilitator superfamily K08151 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 431.0
HFD3_k127_6311418_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 368.0
HFD3_k127_6311418_2 Protein of unknown function (DUF3224) - - - 0.0000000000000000000000000002829 117.0
HFD3_k127_6311418_4 transmembrane transporter activity - - - 0.0000001062 57.0
HFD3_k127_6316300_1 Two component transcriptional regulator, winged helix family K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001978 284.0
HFD3_k127_6316300_2 - - - - 0.000000000000000000000000000000000000000000000000000009276 205.0
HFD3_k127_6316300_3 histidine kinase HAMP region domain protein K02484,K07642 - 2.7.13.3 0.000000000000000000000000000000000000000000000396 179.0
HFD3_k127_6316300_4 lysozyme - - - 0.00003515 52.0
HFD3_k127_6327300_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 2.89e-213 670.0
HFD3_k127_6327300_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 1.702e-207 664.0
HFD3_k127_6327300_2 V-type ATPase 116kDa subunit family K02123 - - 0.00000000000000000000000000000000000000000000001943 176.0
HFD3_k127_6327300_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.0000000000000000000000000000000000000000000007495 181.0
HFD3_k127_6327300_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.00000000000000000000000000000000000004754 147.0
HFD3_k127_6327300_5 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.00000000000001013 81.0
HFD3_k127_6327300_6 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0008150,GO:0015075,GO:0015399,GO:0015405,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022853,GO:0022857,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0090662,GO:0098660,GO:0099131 - 0.000000000003032 71.0
HFD3_k127_6327300_7 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.00000000002162 73.0
HFD3_k127_6336989_0 COGs COG1653 ABC-type sugar transport system periplasmic component K02027 - - 3.681e-196 621.0
HFD3_k127_6336989_1 Protein of unknown function (DUF1343) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 513.0
HFD3_k127_6336989_2 COGs COG0395 ABC-type sugar transport system permease component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 445.0
HFD3_k127_6336989_3 COGs COG1175 ABC-type sugar transport systems permease components K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000607 441.0
HFD3_k127_6336989_4 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000006896 222.0
HFD3_k127_6336989_5 SMART Metal-dependent phosphohydrolase, HD region K07023 - - 0.000000000000000002453 87.0
HFD3_k127_6342302_0 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 344.0
HFD3_k127_6342302_1 Stage II sporulation protein M - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008129 348.0
HFD3_k127_6342302_2 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000806 283.0
HFD3_k127_6342302_3 PFAM NMT1 THI5 like domain protein K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008652 273.0
HFD3_k127_6342302_4 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000003917 256.0
HFD3_k127_6342302_5 Alpha/beta hydrolase of unknown function (DUF1100) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001835 261.0
HFD3_k127_6342302_6 PFAM binding-protein-dependent transport systems inner membrane component K02050 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000004371 226.0
HFD3_k127_6342302_7 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.00000000000000000000000000000000000002416 153.0
HFD3_k127_6342302_8 belongs to the sigma-70 factor family, ECF subfamily - - - 0.000000000000000000000003485 106.0
HFD3_k127_6342302_9 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000003248 60.0
HFD3_k127_6345735_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000978 403.0
HFD3_k127_6345735_1 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000000000000000103 128.0
HFD3_k127_6349749_0 Predicted membrane protein (DUF2085) - - - 0.0000000000000000000000000000000000733 140.0
HFD3_k127_6349749_1 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000004889 98.0
HFD3_k127_6349749_2 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000006612 86.0
HFD3_k127_6349749_3 - - - - 0.000001544 57.0
HFD3_k127_6353571_0 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006019 262.0
HFD3_k127_6353571_1 Amidohydrolase K03392 - 4.1.1.45 0.000000000000000000000000000000000000000000000000000000000461 209.0
HFD3_k127_6353571_2 NMT1/THI5 like - - - 0.00000000000000000000000000000000000000000000000003406 194.0
HFD3_k127_6353571_3 PFAM Nitroreductase - - - 0.0000000000000001333 83.0
HFD3_k127_6353916_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1770.0
HFD3_k127_6353916_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004627 526.0
HFD3_k127_6353916_2 ThiF family K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 394.0
HFD3_k127_6362272_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 429.0
HFD3_k127_6362272_1 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 359.0
HFD3_k127_6362272_2 helix_turn_helix, Lux Regulon K11618 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002874 250.0
HFD3_k127_6362272_3 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006953 253.0
HFD3_k127_6362272_4 ATP-binding region ATPase domain protein K07683 - 2.7.13.3 0.0000000000000000000000000000000000000000000000258 190.0
HFD3_k127_6362272_5 histidine kinase dimerisation and phosphoacceptor region - - - 0.0000000000000000000000000000002031 140.0
HFD3_k127_6362272_6 Cytochrome c - - - 0.00000002914 65.0
HFD3_k127_6362272_7 cheY-homologous receiver domain K03413 - - 0.00000008294 59.0
HFD3_k127_6367165_0 SMART Adenylyl cyclase class-3 4 guanylyl cyclase - - - 3.261e-196 658.0
HFD3_k127_6367165_1 Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7' K02293 - 1.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007882 627.0
HFD3_k127_6367165_2 PFAM metallophosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002409 238.0
HFD3_k127_6367165_3 activity, protein serine threonine kinase activity, protein-tyrosine kinase activity, ATP binding, regulation of transcription, DNA-dependent, protein amino acid phosphorylation K08282,K13419 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000006323 234.0
HFD3_k127_6367165_4 - - - - 0.000000000000000000000000000000000000000000000003887 199.0
HFD3_k127_6367165_5 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000006548 174.0
HFD3_k127_6378566_0 Malate/L-lactate dehydrogenase K00073 - 1.1.1.350 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009929 349.0
HFD3_k127_6378566_1 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 330.0
HFD3_k127_6378566_2 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002324 302.0
HFD3_k127_6379710_0 MFS_1 like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001773 251.0
HFD3_k127_6379710_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000002957 214.0
HFD3_k127_6379710_2 Male sterility protein - - - 0.0000000000000000000000000000000000000000001227 169.0
HFD3_k127_6379710_3 GDP-mannose mannosyl hydrolase activity K03574,K13669 - 3.6.1.55 0.000000000008022 70.0
HFD3_k127_6385022_0 PFAM band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004349 331.0
HFD3_k127_6385022_1 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000038 309.0
HFD3_k127_6385022_2 Cold shock K03704 - - 0.0000000000000000000000167 102.0
HFD3_k127_6385022_3 WD40 domain protein beta Propeller K03641 - - 0.00000000000003243 85.0
HFD3_k127_6391178_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1513.0
HFD3_k127_6391178_1 PFAM Ferredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005663 286.0
HFD3_k127_6391178_2 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000006321 220.0
HFD3_k127_6391178_3 4Fe-4S dicluster domain K00125,K03646 - 1.17.1.9 0.0000000000000000000000000000000008697 139.0
HFD3_k127_6391178_4 heterodisulfide reductase K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000003939 58.0
HFD3_k127_6391178_5 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000009229 49.0
HFD3_k127_6391920_0 trisaccharide binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 336.0
HFD3_k127_6391920_1 RimK-like ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000005553 233.0
HFD3_k127_6392509_0 PFAM sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004791 411.0
HFD3_k127_6392509_1 PFAM glycosyl transferase family 2 K07011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006541 302.0
HFD3_k127_6393176_0 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001303 267.0
HFD3_k127_6393176_1 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000005259 237.0
HFD3_k127_6393176_2 PFAM Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000004287 155.0
HFD3_k127_6393176_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000002872 142.0
HFD3_k127_6393846_0 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 600.0
HFD3_k127_6393846_1 COGs COG0524 Sugar kinase ribokinase family - - - 0.00000000000000000000000000000000000000000000000000000000001677 216.0
HFD3_k127_6393846_2 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.0000000000000004525 77.0
HFD3_k127_6396630_0 Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 7.207e-284 905.0
HFD3_k127_6396630_1 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000006091 253.0
HFD3_k127_6396630_2 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000000000000000000000000000000000000000001022 171.0
HFD3_k127_6399685_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 487.0
HFD3_k127_6399685_1 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 452.0
HFD3_k127_6399685_10 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000001028 168.0
HFD3_k127_6399685_11 - - - - 0.000000000000000000000000000000001074 140.0
HFD3_k127_6399685_2 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008154 401.0
HFD3_k127_6399685_3 NUDIX domain K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006638 382.0
HFD3_k127_6399685_4 Pyruvate:ferredoxin oxidoreductase core domain II K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007163 352.0
HFD3_k127_6399685_5 Carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007154 286.0
HFD3_k127_6399685_6 Pyruvate ferredoxin/flavodoxin oxidoreductase K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000003758 282.0
HFD3_k127_6399685_7 Putative glycosyl hydrolase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001398 285.0
HFD3_k127_6399685_8 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000004061 203.0
HFD3_k127_6399685_9 pseudouridine synthase activity K06178,K06181,K06183 - 5.4.99.19,5.4.99.20,5.4.99.22 0.00000000000000000000000000000000000000000004987 183.0
HFD3_k127_6421744_0 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002241 249.0
HFD3_k127_6421744_1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000003062 185.0
HFD3_k127_6437695_0 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 612.0
HFD3_k127_6437695_1 N-terminal 7TM region of histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000006986 205.0
HFD3_k127_6437695_2 MarR family - - - 0.000000000000000000000000000000000000000000000000181 183.0
HFD3_k127_6437695_3 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000001026 140.0
HFD3_k127_6442679_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K13924 - 2.1.1.80,3.1.1.61 2.186e-298 949.0
HFD3_k127_6442679_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007467 471.0
HFD3_k127_6442679_10 PFAM DNA repair protein RadC K03630 - - 0.0000000000003275 76.0
HFD3_k127_6442679_11 - - - - 0.0000000001372 70.0
HFD3_k127_6442679_12 Glyoxalase-like domain - - - 0.000000001068 64.0
HFD3_k127_6442679_2 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004489 320.0
HFD3_k127_6442679_3 geranylgeranyl reductase activity K14266 - 1.14.19.9 0.00000000000000000000000000000000000000000000000001637 186.0
HFD3_k127_6442679_4 ABC-2 family transporter protein K01992,K19341 - - 0.0000000000000000000000000000000000000000000000008324 184.0
HFD3_k127_6442679_5 bacterial-type flagellum-dependent cell motility K16147 - 2.4.99.16 0.0000000000000000000000000000000000000000000177 175.0
HFD3_k127_6442679_6 - - - - 0.00000000000000000000000000000007551 128.0
HFD3_k127_6442679_7 glycosyl hydrolase, BNR repeat-containing protein - - - 0.000000000000000000002327 101.0
HFD3_k127_6442679_8 WD40-like Beta Propeller Repeat K03641 - - 0.0000000000000000000322 103.0
HFD3_k127_6442679_9 Peptidoglycan-binding domain 1 protein - - - 0.000000000000006499 88.0
HFD3_k127_6446830_0 sigma factor activity K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003919 592.0
HFD3_k127_6446830_1 phospholipase C K01114 - 3.1.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 597.0
HFD3_k127_6446830_2 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000042 297.0
HFD3_k127_6446830_3 YCII-related domain - - - 0.0000000000000000000000000000000000001724 144.0
HFD3_k127_6446830_4 - - - - 0.000000000001 74.0
HFD3_k127_6447124_0 carboxylic acid catabolic process K02549 GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.2.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006595 556.0
HFD3_k127_6447124_1 phosphoglycerate mutase K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 491.0
HFD3_k127_6447124_10 - - - - 0.00002123 56.0
HFD3_k127_6447124_2 Predicted membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 485.0
HFD3_k127_6447124_3 virion core protein, lumpy skin disease virus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 408.0
HFD3_k127_6447124_4 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007487 289.0
HFD3_k127_6447124_5 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000001456 214.0
HFD3_k127_6447124_6 PspA/IM30 family K01153,K03615,K03969,K11942,K15842 GO:0003674,GO:0005488,GO:0005515,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006950,GO:0008150,GO:0008289,GO:0009266,GO:0009271,GO:0009408,GO:0009605,GO:0009607,GO:0009615,GO:0009628,GO:0009889,GO:0009898,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019897,GO:0019898,GO:0031234,GO:0031323,GO:0031326,GO:0042802,GO:0043167,GO:0043168,GO:0043207,GO:0043433,GO:0044092,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0048519,GO:0050789,GO:0050794,GO:0050896,GO:0051090,GO:0051171,GO:0051252,GO:0051704,GO:0051707,GO:0060187,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0098552,GO:0098562,GO:0098586,GO:1903506,GO:2000112,GO:2001141 3.1.21.3,5.4.99.13 0.00000000000000000000000000000000000000000000000000000001674 205.0
HFD3_k127_6447124_7 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000000000000204 181.0
HFD3_k127_6447124_8 acetyltransferase K06889,K19273 - - 0.000000000000000000001599 100.0
HFD3_k127_6447124_9 PFAM ABC transporter related K05816,K10112 - 3.6.3.20 0.000006107 49.0
HFD3_k127_6448254_0 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000002289 237.0
HFD3_k127_6448254_1 thiolester hydrolase activity - - - 0.000000000000000000000000000000000784 141.0
HFD3_k127_6448254_2 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000006305 119.0
HFD3_k127_6448420_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000005657 204.0
HFD3_k127_6448420_1 glycogen (starch) synthase activity K00703,K00754 - 2.4.1.21 0.0000000000000000000000000000000000006092 156.0
HFD3_k127_6448420_2 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000003145 122.0
HFD3_k127_6448420_3 Methyltransferase K00568 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.1.1.222,2.1.1.64 0.00000001116 60.0
HFD3_k127_6448420_4 COG0457 FOG TPR repeat - - - 0.00001205 55.0
HFD3_k127_6448420_5 O-antigen ligase - - - 0.0001129 55.0
HFD3_k127_64502_0 SMART phosphoesterase PHP domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 552.0
HFD3_k127_64502_1 Peptidase family S58 K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 306.0
HFD3_k127_64502_2 GCN5 family acetyltransferase K22477 - 2.3.1.1 0.0000000000000000000000000000002698 127.0
HFD3_k127_64502_3 Polysaccharide deacetylase K22278 - 3.5.1.104 0.0000000000000000000000001085 120.0
HFD3_k127_6451371_0 Enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007684 320.0
HFD3_k127_6451371_1 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex - - - 0.00000000000000000000000000000000000000000000000002087 198.0
HFD3_k127_6451371_2 Putative stress-induced transcription regulator - - - 0.000000000000000000000000000000000000000000001195 173.0
HFD3_k127_6460893_0 Endoribonuclease that initiates mRNA decay K18682 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 558.0
HFD3_k127_6460893_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 492.0
HFD3_k127_6460893_10 DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000001136 246.0
HFD3_k127_6460893_11 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000379 237.0
HFD3_k127_6460893_12 zinc metalloprotease K04771,K11749,K16922 GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016021,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0040007,GO:0043170,GO:0043856,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045152,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:0140110,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000001164 223.0
HFD3_k127_6460893_13 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000000000000000002124 186.0
HFD3_k127_6460893_14 Modulates RecA activity K03565 - - 0.0000000000000000000000000000000000000000000001664 174.0
HFD3_k127_6460893_15 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000001103 160.0
HFD3_k127_6460893_16 Lipopolysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000008564 156.0
HFD3_k127_6460893_17 PFAM NUDIX domain - - - 0.000000000000000000000000000001024 127.0
HFD3_k127_6460893_18 capsule polysaccharide biosynthetic process K16692 - - 0.0000000000000000000000000001057 124.0
HFD3_k127_6460893_19 PFAM Stage V sporulation protein S K06416 - - 0.000000000000000000000000001787 115.0
HFD3_k127_6460893_2 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710,K12450 GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 4.2.1.46,4.2.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 471.0
HFD3_k127_6460893_20 GHMP kinases N terminal domain K01597 - 4.1.1.33 0.000000000000000000000000002969 114.0
HFD3_k127_6460893_21 response regulator - - - 0.000000000000000012 98.0
HFD3_k127_6460893_22 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0000000000000006815 84.0
HFD3_k127_6460893_3 Thiolase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004711 456.0
HFD3_k127_6460893_4 PFAM Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009378 452.0
HFD3_k127_6460893_5 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 376.0
HFD3_k127_6460893_6 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000004302 268.0
HFD3_k127_6460893_7 Psort location Cytoplasmic, score K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000001971 265.0
HFD3_k127_6460893_8 TIGRFAM capsular exopolysaccharide family K08253 - 2.7.10.2 0.000000000000000000000000000000000000000000000000000000000000000000000002226 250.0
HFD3_k127_6460893_9 PFAM PSP1 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005238 252.0
HFD3_k127_6476584_0 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006254 488.0
HFD3_k127_6476584_1 CO dehydrogenase flavoprotein K03519 - 1.2.5.3 0.0000002526 55.0
HFD3_k127_6476584_2 Sugar (and other) transporter - - - 0.00003331 46.0
HFD3_k127_6484465_0 BFD-like [2Fe-2S] binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003913 263.0
HFD3_k127_6484465_1 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000003571 256.0
HFD3_k127_6484465_2 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000002905 184.0
HFD3_k127_6484465_3 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000329 131.0
HFD3_k127_6490616_0 Putative glucoamylase K13688 - - 0.0 2555.0
HFD3_k127_6490616_1 Rhodanese Homology Domain K01069 - 3.1.2.6 0.00000000000000000000004076 102.0
HFD3_k127_6498287_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 1.521e-266 833.0
HFD3_k127_6498287_1 Periplasmic binding protein K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005653 448.0
HFD3_k127_6498287_2 PFAM inner-membrane translocator K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 414.0
HFD3_k127_6498287_3 PFAM ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 386.0
HFD3_k127_6498287_4 CBS domain K04767 - - 0.0000000000000000000000000000000000000000000000000000000000000000007846 234.0
HFD3_k127_6498287_5 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000421 184.0
HFD3_k127_6498287_6 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000006363 183.0
HFD3_k127_6498287_7 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000001874 136.0
HFD3_k127_6498287_8 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000005435 124.0
HFD3_k127_6498287_9 Archaebacterial flagellin - - - 0.000000000004079 75.0
HFD3_k127_6499148_0 Domain of unknown function (DUF348) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007133 340.0
HFD3_k127_6499148_1 TIGRFAM Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005466 280.0
HFD3_k127_6499148_2 Diguanylate cyclase, GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004357 277.0
HFD3_k127_6499148_3 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000385 253.0
HFD3_k127_6499148_4 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.000000000000000000000000000000000000000000000000000268 188.0
HFD3_k127_6499148_5 - - - - 0.00000000000000000000000002271 111.0
HFD3_k127_6499148_6 Putative regulatory protein - - - 0.00000000000000000000002184 102.0
HFD3_k127_6503055_0 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002633 278.0
HFD3_k127_6503055_1 Histidine kinase K02480 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000008157 246.0
HFD3_k127_6503055_2 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000002487 233.0
HFD3_k127_6503055_3 PFAM regulatory protein LuxR - - - 0.000000000000000000000000000000001459 131.0
HFD3_k127_6503055_4 HlyD family secretion protein K02005,K13888 - - 0.00000000000001139 77.0
HFD3_k127_6503223_0 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000000000000001346 269.0
HFD3_k127_6503223_1 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000005276 162.0
HFD3_k127_6503223_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000008834 50.0
HFD3_k127_6513884_0 COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K12528 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004618 573.0
HFD3_k127_6513884_1 Thioredoxin - - - 0.000000000000000000000000000005435 124.0
HFD3_k127_6513884_2 COGs COG4591 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000004891 55.0
HFD3_k127_6532646_0 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 412.0
HFD3_k127_6532646_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00282 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006807,GO:0008150,GO:0008152,GO:0009069,GO:0009987,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019752,GO:0032991,GO:0042133,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901605,GO:1902494,GO:1990204 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000005057 257.0
HFD3_k127_6532646_2 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000006767 160.0
HFD3_k127_6532646_3 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.000000000000000002489 86.0
HFD3_k127_6532646_4 hydroxymethylglutaryl-CoA reductase K00021 - 1.1.1.34 0.000000000000006514 80.0
HFD3_k127_6534438_0 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000006929 231.0
HFD3_k127_6534438_1 PFAM methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000122 215.0
HFD3_k127_6534438_2 Protein of unknown function (DUF1461) - - - 0.000000000000000000001488 102.0
HFD3_k127_6534438_3 Short C-terminal domain K08982 - - 0.000000000005337 72.0
HFD3_k127_6534438_4 Short C-terminal domain K08982 - - 0.000000000005627 69.0
HFD3_k127_6537334_0 Molybdopterin oxidoreductase Fe4S4 domain K00336 - 1.6.5.3 5.663e-271 850.0
HFD3_k127_6555713_0 family 4 K07406 - 3.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 434.0
HFD3_k127_6555713_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000004989 235.0
HFD3_k127_6555713_2 Belongs to the 'phage' integrase family. XerC subfamily K04763 - - 0.000000000000000000001607 100.0
HFD3_k127_6558408_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 3.752e-215 694.0
HFD3_k127_6558408_1 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008364 303.0
HFD3_k127_6558408_2 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000007658 262.0
HFD3_k127_6558408_3 adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000002464 222.0
HFD3_k127_6558408_4 PFAM sigma-70 region 2 domain protein K03088 - - 0.0000000000000000000000000000000000000000000000000000000294 202.0
HFD3_k127_6558408_6 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K21563 - - 0.00000004035 61.0
HFD3_k127_6575080_0 Polynucleotide adenylyltransferase region K00974 - 2.7.7.72 1.991e-203 659.0
HFD3_k127_6575080_1 Glycogen debranching enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007815 314.0
HFD3_k127_6578324_0 PFAM Cytochrome C assembly protein K02198 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 596.0
HFD3_k127_6578324_1 PFAM cytochrome c-type biogenesis protein CcmB K02194 - - 0.0000000000000000000000000000000000000000000000000000000002869 211.0
HFD3_k127_6578324_2 PFAM ABC transporter related K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000000000001873 206.0
HFD3_k127_6578324_3 Cytochrome c - - - 0.00000000000000000000003048 113.0
HFD3_k127_6578324_4 PFAM Cytochrome c assembly protein K02195 - - 0.0000000000000000001127 91.0
HFD3_k127_6578324_5 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000185 95.0
HFD3_k127_6578324_6 - - - - 0.00000009015 61.0
HFD3_k127_6581768_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006308 564.0
HFD3_k127_6581768_1 PFAM Transketolase central region K21417 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 525.0
HFD3_k127_6581768_10 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.00000000000000000000000000000002975 131.0
HFD3_k127_6581768_11 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000005942 130.0
HFD3_k127_6581768_12 PTS HPr component phosphorylation site K11189 - - 0.00000000000000000000003438 101.0
HFD3_k127_6581768_13 Bacterial transcriptional regulator - - - 0.000000000001294 74.0
HFD3_k127_6581768_2 Catalytic domain of components of various dehydrogenase complexes K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 424.0
HFD3_k127_6581768_3 Putative sugar-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 347.0
HFD3_k127_6581768_4 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001578 280.0
HFD3_k127_6581768_5 PTS system glucitol sorbitol-specific K02783 GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0051179,GO:0051234,GO:0071702 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004412 271.0
HFD3_k127_6581768_6 protein-phosphocysteine-sugar phosphotransferase activity K02782,K02783 - 2.7.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000007816 265.0
HFD3_k127_6581768_7 protein-phosphocysteine-sugar phosphotransferase activity K02782,K02783 - 2.7.1.198 0.000000000000000000000000000000000000000000000000000000000000000000003839 235.0
HFD3_k127_6581768_9 PTS system glucitol sorbitol-specific IIA component K02781 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0009401,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0051179,GO:0051234,GO:0071702 2.7.1.198 0.000000000000000000000000000000000004447 140.0
HFD3_k127_65939_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 1.186e-231 736.0
HFD3_k127_65939_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 1.042e-212 663.0
HFD3_k127_65939_2 histidine kinase HAMP region domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 431.0
HFD3_k127_65939_3 Two component transcriptional regulator, winged helix family K07658 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 306.0
HFD3_k127_65939_4 Mannosyltransferase (PIG-V) - - - 0.000000000000000000000000001239 128.0
HFD3_k127_6596657_0 lactate metabolic process K00113 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0045333,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006445 323.0
HFD3_k127_6596657_1 Ferric uptake regulator family K03711,K09825 - - 0.00000000000000000000000000000000000000002539 160.0
HFD3_k127_6610660_0 Caspase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006392 284.0
HFD3_k127_6610660_1 ECF transporter, substrate-specific component - - - 0.00000000000000007133 95.0
HFD3_k127_6614986_0 ABC transporter K06147 - - 2.172e-235 746.0
HFD3_k127_6614986_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 471.0
HFD3_k127_6614986_10 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003994 270.0
HFD3_k127_6614986_11 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002214 252.0
HFD3_k127_6614986_12 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015934,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031325,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000232,GO:2000234 - 0.0000000000000000000000000000000000000000000000000000000000000000000000004157 252.0
HFD3_k127_6614986_13 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000001814 251.0
HFD3_k127_6614986_14 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000002399 253.0
HFD3_k127_6614986_15 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000497 243.0
HFD3_k127_6614986_16 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000000000003667 224.0
HFD3_k127_6614986_17 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000002993 216.0
HFD3_k127_6614986_18 Forms part of the polypeptide exit tunnel K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000008156 219.0
HFD3_k127_6614986_19 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0030312,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000001913 219.0
HFD3_k127_6614986_2 Associated with various cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 464.0
HFD3_k127_6614986_20 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000001942 205.0
HFD3_k127_6614986_21 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000000004894 201.0
HFD3_k127_6614986_22 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000000000000001024 191.0
HFD3_k127_6614986_23 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000004791 186.0
HFD3_k127_6614986_24 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000001285 182.0
HFD3_k127_6614986_25 Binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000000000000005431 182.0
HFD3_k127_6614986_26 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000006457 166.0
HFD3_k127_6614986_27 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000001246 158.0
HFD3_k127_6614986_28 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000000371 154.0
HFD3_k127_6614986_29 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000002366 146.0
HFD3_k127_6614986_3 VWA domain containing CoxE-like protein K07161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 422.0
HFD3_k127_6614986_30 One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000006923 144.0
HFD3_k127_6614986_31 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000004447 140.0
HFD3_k127_6614986_32 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000002146 132.0
HFD3_k127_6614986_33 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000007551 122.0
HFD3_k127_6614986_34 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000001456 109.0
HFD3_k127_6614986_35 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000000000008364 101.0
HFD3_k127_6614986_36 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000001554 95.0
HFD3_k127_6614986_37 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) K02907 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000001564 84.0
HFD3_k127_6614986_38 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000005954 71.0
HFD3_k127_6614986_39 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000004007 71.0
HFD3_k127_6614986_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 410.0
HFD3_k127_6614986_40 - - - - 0.00001681 50.0
HFD3_k127_6614986_5 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 397.0
HFD3_k127_6614986_6 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 318.0
HFD3_k127_6614986_7 UbiA prenyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 295.0
HFD3_k127_6614986_8 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001338 285.0
HFD3_k127_6614986_9 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002317 268.0
HFD3_k127_663088_0 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009177 286.0
HFD3_k127_663088_1 C-terminal binding-module, SLH-like, of glucodextranase - - - 0.0000000000000000000000000000000000000000004557 169.0
HFD3_k127_6631101_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 386.0
HFD3_k127_6631101_1 ABC transporter K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000893 250.0
HFD3_k127_6631101_2 metal-dependent hydrolase of the TIM-barrel fold K03392,K22213 - 4.1.1.45,4.1.1.52 0.0000000000000002968 83.0
HFD3_k127_6633094_0 Glycosyl transferase 4-like domain K08256 - 2.4.1.345 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 350.0
HFD3_k127_6633094_1 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009805 274.0
HFD3_k127_6633094_2 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003653 249.0
HFD3_k127_6633094_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000003708 96.0
HFD3_k127_6645371_0 PFAM natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 390.0
HFD3_k127_6645371_1 GAF domain - - - 0.0000000000000000000000000000000000000000000000000005309 208.0
HFD3_k127_6645371_2 Domain of unknown function (DUF4118) - - - 0.00003342 57.0
HFD3_k127_6645701_0 Transposase DDE domain - - - 2.981e-194 608.0
HFD3_k127_6645701_1 FAD binding domain K00480,K14974 - 1.14.13.1,1.14.13.114 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009069 359.0
HFD3_k127_6654355_0 Threonine dehydrogenase and related Zn-dependent K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008326 313.0
HFD3_k127_6654355_1 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007166 294.0
HFD3_k127_6654355_2 Cupin - - - 0.000000000000000000000000000000000000000000002177 176.0
HFD3_k127_6659015_0 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009023 549.0
HFD3_k127_6659015_1 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004076 543.0
HFD3_k127_6659015_2 Psort location CytoplasmicMembrane, score K00368,K07233,K22349 - 1.16.3.3,1.7.2.1 0.0000000000000000000001923 114.0
HFD3_k127_6673375_0 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000006862 183.0
HFD3_k127_6673375_1 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000003229 187.0
HFD3_k127_6673375_2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides K09020 - 3.5.1.110 0.000000000000000000000000000000000007307 145.0
HFD3_k127_6673375_3 UTRA K03710 - - 0.0000000000000000002269 95.0
HFD3_k127_6673375_4 Acetoacetate decarboxylase (ADC) - - - 0.00000000000143 78.0
HFD3_k127_6673375_5 Carboxymuconolactone decarboxylase family - - - 0.00004266 50.0
HFD3_k127_6676320_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008068 393.0
HFD3_k127_6676320_1 ABC-type multidrug transport system, ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 362.0
HFD3_k127_6676320_2 PFAM ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004235 275.0
HFD3_k127_6676320_3 ABC-2 family transporter protein - - - 0.00000000000000000000000000000000000000000000002533 181.0
HFD3_k127_6676320_4 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000002951 156.0
HFD3_k127_6676320_5 ABC-2 type transporter K01992 - - 0.0000000000000002623 90.0
HFD3_k127_6676320_6 ABC-2 type transporter K01992 - - 0.000000007051 67.0
HFD3_k127_6676320_7 CAAX protease self-immunity - - - 0.0004689 51.0
HFD3_k127_6699597_0 histidine kinase, dimerisation and phosphoacceptor region - - - 0.00000000000000000000000000000000000000000000000000000000000936 231.0
HFD3_k127_6699597_1 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000001653 174.0
HFD3_k127_6699597_2 WD40-like Beta Propeller Repeat K03641 - - 0.000000000000000000000000000005101 132.0
HFD3_k127_6736929_0 TIGRFAM Acetoacetyl-CoA synthase K01907 - 6.2.1.16 3.825e-257 801.0
HFD3_k127_6736929_1 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000001331 233.0
HFD3_k127_6736929_2 xanthine dehydrogenase activity K04108 - 1.3.7.9 0.000000000000000000000000000000000000000000000000000000000000000007645 229.0
HFD3_k127_6736929_3 helix_turn_helix isocitrate lyase regulation - - - 0.000000000000000000000000000000001299 140.0
HFD3_k127_6767053_0 - - - - 0.00000000000000000000000005108 111.0
HFD3_k127_6767053_1 Protein of unknown function (DUF3105) - - - 0.0000000000000000000000001147 114.0
HFD3_k127_6767053_2 hydrolase K07025 - - 0.0000000000000000008908 92.0
HFD3_k127_6851797_0 Hydrolase CocE NonD family K06978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 379.0
HFD3_k127_6851797_1 Thioesterase K07107,K12500 - - 0.00000000000000000000000000000000000000000000000000001042 193.0
HFD3_k127_6851797_3 PFAM amidohydrolase K01464 - 3.5.2.2 0.000003394 49.0
HFD3_k127_6873770_0 Belongs to the HpcH HpaI aldolase family K01644,K08691 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006107,GO:0008150,GO:0008152,GO:0009987,GO:0015977,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0043167,GO:0043169,GO:0043427,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0046872,GO:0047777,GO:0050083,GO:0071704 4.1.3.24,4.1.3.25,4.1.3.34 0.000000000000000000000000000000000000000000000000000002117 198.0
HFD3_k127_6873770_1 Acetyltransferase (GNAT) domain K03824 - - 0.000000000000000004928 85.0
HFD3_k127_6873770_2 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000008167 81.0
HFD3_k127_6900659_0 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005714 361.0
HFD3_k127_6900659_1 Spermidine putrescine ABC transporter substrate-binding protein K02055 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000172 286.0
HFD3_k127_6900659_2 Binding-protein-dependent transport system inner membrane component K02054,K11071 - - 0.00000000000000000000000000000000000000000000000000000000000001255 229.0
HFD3_k127_6900659_3 Binding-protein-dependent transport system inner membrane component K11082 - - 0.00000000000000000000000000000000000000000000000000000000122 212.0
HFD3_k127_6900659_4 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000572 209.0
HFD3_k127_6900659_5 Nitroreductase family K21375 - 1.3.3.13 0.00000000000000000000000000000000000000000000000000001212 195.0
HFD3_k127_6900659_6 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.0000000000000000000000000000000000000003475 162.0
HFD3_k127_6900659_7 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.00000000000000000000000000000000001463 148.0
HFD3_k127_6900659_8 - - - - 0.00000000000000005493 85.0
HFD3_k127_6956960_0 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001485 278.0
HFD3_k127_6956960_1 NUDIX domain - - - 0.0000000000000000000000000000000000000001854 156.0
HFD3_k127_6956960_2 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 0.0000000000000005648 79.0
HFD3_k127_6956960_3 Major facilitator superfamily - - - 0.00000000000002162 78.0
HFD3_k127_6956960_4 Serine threonine protein kinase K08884 - 2.7.11.1 0.000000001179 70.0
HFD3_k127_695826_0 GTP binding - - - 0.0000000000000000000000000000000000000000000000000000000000000001938 234.0
HFD3_k127_695826_1 HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000000004638 205.0
HFD3_k127_695826_2 competence protein - - - 0.00000000000000000000000000000000000000000000000002571 187.0
HFD3_k127_695826_3 Adenylate Guanylate cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000008206 188.0
HFD3_k127_695826_4 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000000000000000000000000000007157 169.0
HFD3_k127_695826_5 Glycosyl transferase family group 2 K07011 - - 0.00000000000000000000000000000000000000001889 158.0
HFD3_k127_695826_6 Low molecular weight phosphotyrosine protein phosphatase K01104,K20201 - 3.1.3.48,3.9.1.2 0.00000000000000000000000000000001101 132.0
HFD3_k127_6965278_0 Methyltransferase domain K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000001899 270.0
HFD3_k127_6965278_1 oligosaccharyl transferase activity - - - 0.00000000000000000000000000000000000000000000000000003018 200.0
HFD3_k127_6965278_2 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000006665 143.0
HFD3_k127_6968605_0 Belongs to the thiolase family K00626 - 2.3.1.9 8.507e-212 664.0
HFD3_k127_6968605_1 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000000000000000000000000000002017 237.0
HFD3_k127_6968605_2 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000001994 190.0
HFD3_k127_6968605_3 phosphate transport regulator (Distant homolog of PhoU) K07220 - - 0.00000000000000000000000000000000000000000000007894 177.0
HFD3_k127_6968605_4 Two component transcriptional regulator, winged helix family - - - 0.0000000000000000000000000000000000000000000009862 175.0
HFD3_k127_6968605_5 PFAM Roadblock LC7 family protein K07131 - - 0.0000000000000000000000000000000000000001133 159.0
HFD3_k127_6968605_6 manually curated - - - 0.0000000000000000000005153 103.0
HFD3_k127_6968605_7 Histidine kinase - - - 0.000000000000006149 79.0
HFD3_k127_6985935_0 PFAM transposase IS116 IS110 IS902 family K07486 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 586.0
HFD3_k127_6985935_1 NmrA-like family K01784,K19997 - 5.1.3.2,5.1.3.26 0.000000000000000000000000000000000000000000000000000000000000000000000004877 256.0
HFD3_k127_6985935_2 ABC transporter substrate binding protein - - - 0.000000000000000000000000000000000000009597 147.0
HFD3_k127_6988409_0 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009194 482.0
HFD3_k127_6988409_1 Short-chain Dehydrogenase reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 324.0
HFD3_k127_6988409_2 Zn-dependent dipeptidase, microsomal dipeptidase K01273,K01274 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 321.0
HFD3_k127_6988409_3 PFAM copper resistance protein CopC - - - 0.000000000000000000000000000000000000000000000000000000002066 224.0
HFD3_k127_6988409_4 Domain of unknown function (DUF4442) - - - 0.000000000000000000000000000000000000000000000000006549 186.0
HFD3_k127_6988409_5 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000001173 188.0
HFD3_k127_6988409_6 PFAM sigma-70 region 2 domain protein K03088 - - 0.00000000000000000001583 94.0
HFD3_k127_6988638_0 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K21417 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009278 558.0
HFD3_k127_6988638_1 PFAM dehydrogenase E1 component K21416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 487.0
HFD3_k127_6988638_2 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004079 388.0
HFD3_k127_6988638_3 FCD - - - 0.000000000000000000000000000000000000000000000000000000000000000000002848 242.0
HFD3_k127_6988638_4 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000001203 214.0
HFD3_k127_6988638_5 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000001648 155.0
HFD3_k127_6988638_6 Lipocalin-like domain - - - 0.0000000000000000000000000000004257 132.0
HFD3_k127_6992485_0 Psort location CytoplasmicMembrane, score K00368,K07233,K22349 - 1.16.3.3,1.7.2.1 0.0000000000000000000000000000000000000000000000000001844 206.0
HFD3_k127_6992485_1 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000003656 154.0
HFD3_k127_6994885_0 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 376.0
HFD3_k127_6994885_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000002898 232.0
HFD3_k127_6994885_2 PFAM extracellular solute-binding protein family 1 K02040 - - 0.0000000000000000000000000000000000000000008253 167.0
HFD3_k127_6994885_3 Protein of unknown function (DUF1501) - - - 0.0000001373 56.0
HFD3_k127_700104_0 arginyl-tRNA aminoacylation K01887 - 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004634 542.0
HFD3_k127_700104_1 Bacterial membrane protein YfhO - - - 0.00000000000000000000001419 114.0
HFD3_k127_700104_2 PLD-like domain - - - 0.00000000001202 75.0
HFD3_k127_7001245_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 409.0
HFD3_k127_7001245_1 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 324.0
HFD3_k127_7001245_2 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 310.0
HFD3_k127_7001245_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006673 300.0
HFD3_k127_7001245_4 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000002535 219.0
HFD3_k127_7001245_5 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000003364 220.0
HFD3_k127_7001245_6 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000001502 164.0
HFD3_k127_7001245_7 N-terminal 7TM region of histidine kinase - - - 0.000000000003158 72.0
HFD3_k127_7004117_0 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.00000000000000000000000000000000000000000008223 168.0
HFD3_k127_7004117_1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02773 - 2.7.1.200 0.0000000000000000000000000003975 120.0
HFD3_k127_7004117_2 BtpA family K06971 - - 0.000000000000000000003245 94.0
HFD3_k127_7004117_3 PTS HPr component phosphorylation site K11189 - - 0.0000000000000000001755 93.0
HFD3_k127_7004117_4 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000004006 64.0
HFD3_k127_7004117_5 protein-N(PI)-phosphohistidine-sugar phosphotransferase activity K02774 - 2.7.1.200 0.0000000034 62.0
HFD3_k127_7004694_0 PFAM ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001049 247.0
HFD3_k127_7004694_1 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000008992 218.0
HFD3_k127_7004694_2 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000005378 79.0
HFD3_k127_7022704_0 oxidative phosphorylation K00426 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002819 474.0
HFD3_k127_7022704_1 PFAM cytochrome bd ubiquinol oxidase subunit I K00425 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006382 420.0
HFD3_k127_7022704_2 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD K16013 - - 0.000000000000000000000000000000000000000000000001852 179.0
HFD3_k127_7027134_0 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000003526 224.0
HFD3_k127_7027134_1 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000004298 159.0
HFD3_k127_7038515_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 5.111e-234 759.0
HFD3_k127_7038515_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 494.0
HFD3_k127_7038515_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007769 414.0
HFD3_k127_7038515_3 Lytic transglycosylase catalytic K08309 - - 0.000000000000000000000000000000000000000000000000001982 208.0
HFD3_k127_7038515_4 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000005833 127.0
HFD3_k127_7038515_5 HEPN domain - - - 0.0000000000000000000000007637 110.0
HFD3_k127_7038515_6 TRANSCRIPTIONal - - - 0.0000000000000000000004458 105.0
HFD3_k127_7038515_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000001271 98.0
HFD3_k127_7040298_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K02182 - 6.2.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 458.0
HFD3_k127_7040298_1 PFAM ABC transporter related K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 297.0
HFD3_k127_7040298_2 Amino acid ABC transporter ATPase K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003222 276.0
HFD3_k127_7040298_3 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006196 265.0
HFD3_k127_7040298_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000001948 224.0
HFD3_k127_7040298_5 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000004384 216.0
HFD3_k127_7040298_6 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000001371 198.0
HFD3_k127_7040298_7 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000000000002689 174.0
HFD3_k127_7040298_8 histidine kinase, dimerisation and phosphoacceptor region - - - 0.00000000000000000000000000000000000000000003635 183.0
HFD3_k127_7040298_9 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000002388 160.0
HFD3_k127_7043027_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 3.678e-222 705.0
HFD3_k127_7043027_1 H( )-stimulated, divalent metal cation uptake system K03322 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 602.0
HFD3_k127_7043027_10 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000002153 142.0
HFD3_k127_7043027_11 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000008681 122.0
HFD3_k127_7043027_12 PFAM NHL repeat containing protein - - - 0.000000000000000000000000007439 123.0
HFD3_k127_7043027_13 Cold-shock protein K03704 - - 0.000000000000000000003962 96.0
HFD3_k127_7043027_14 PFAM RNP-1 like RNA-binding protein - - - 0.00000000000000004507 85.0
HFD3_k127_7043027_15 PFAM Transcription factor CarD K07736 - - 0.000000006079 64.0
HFD3_k127_7043027_16 - - - - 0.0007856 46.0
HFD3_k127_7043027_2 choline dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 322.0
HFD3_k127_7043027_3 ADP-glyceromanno-heptose 6-epimerase activity K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 308.0
HFD3_k127_7043027_4 L-seryl-tRNASec selenium transferase activity K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008847 302.0
HFD3_k127_7043027_5 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009148 264.0
HFD3_k127_7043027_6 Pyridoxal-phosphate dependent enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000004001 233.0
HFD3_k127_7043027_7 iron dependent repressor K03709 - - 0.0000000000000000000000000000000000000000000000000000005774 199.0
HFD3_k127_7043027_8 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000000000000006616 195.0
HFD3_k127_7043027_9 NHL repeat - - - 0.000000000000000000000000000000000001341 152.0
HFD3_k127_7052639_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K05299 - 1.17.1.10,1.17.1.9 2.687e-209 663.0
HFD3_k127_7052639_1 histidine kinase dimerisation and phosphoacceptor region - - - 0.00000000000000000000000000000000000000000000000000001991 199.0
HFD3_k127_7052639_2 Molybdopterin oxidoreductase Fe4S4 region K00336,K05299 - 1.17.1.10,1.6.5.3 0.0000000000000000000000000000000000000000000000189 172.0
HFD3_k127_7053803_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007345 602.0
HFD3_k127_7053803_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 362.0
HFD3_k127_7053803_2 NAD(P)H-binding K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 313.0
HFD3_k127_7053803_3 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000007493 98.0
HFD3_k127_7053803_4 Bacterial membrane protein YfhO - - - 0.000000000000006084 84.0
HFD3_k127_7069999_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 443.0
HFD3_k127_7069999_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 420.0
HFD3_k127_7069999_2 PFAM Alcohol dehydrogenase zinc-binding domain protein K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 356.0
HFD3_k127_7069999_3 Deoxynucleoside kinase K15518 - 2.7.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000002211 255.0
HFD3_k127_7069999_4 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000003874 250.0
HFD3_k127_7069999_5 Deoxynucleoside kinase - - - 0.00000000000000000000000000001785 121.0
HFD3_k127_7092920_0 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 534.0
HFD3_k127_7092920_1 PFAM Branched-chain amino acid transport system permease component K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 338.0
HFD3_k127_7092920_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 317.0
HFD3_k127_7092920_3 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 319.0
HFD3_k127_7092920_4 ABC transporter substrate-binding protein PnrA-like K02058 - - 0.000000000000000000000000000000000000000000000000001243 186.0
HFD3_k127_7092920_5 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000006912 164.0
HFD3_k127_7099072_0 PFAM diacylglycerol kinase catalytic region - - - 0.000000000000000000000000000000000000000000000000000000002505 211.0
HFD3_k127_7099072_1 Flavin reductase like domain - - - 0.000000000000000000000000006795 124.0
HFD3_k127_7099072_2 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000002061 115.0
HFD3_k127_7099072_3 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000001493 70.0
HFD3_k127_7099072_4 PFAM Metalloenzyme - - - 0.0002544 44.0
HFD3_k127_7099689_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001018 280.0
HFD3_k127_7099689_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002617 280.0
HFD3_k127_7099689_2 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000471 95.0
HFD3_k127_7103287_0 PEP-CTERM family integral membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008763 550.0
HFD3_k127_7103287_1 TIGRFAM exosortase archaeosortase family protein - - - 0.00000000000008267 75.0
HFD3_k127_7103287_2 helix_turn_helix multiple antibiotic resistance protein - - - 0.00004552 50.0
HFD3_k127_7109195_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 619.0
HFD3_k127_7109195_1 involved in signal transduction (via phosphorylation) involved in transcriptional regulatory mechanism and in the regulation of secondary metabolites catalytic activity ATP a protein ADP a phosphoprotein K08282 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 554.0
HFD3_k127_7109195_2 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 359.0
HFD3_k127_7109195_3 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005619 282.0
HFD3_k127_7109195_4 3-hydroxyacyl-CoA dehydrogenase K00074 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006635,GO:0008150,GO:0008152,GO:0008610,GO:0008691,GO:0009056,GO:0009058,GO:0009062,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016042,GO:0016053,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019395,GO:0019752,GO:0030258,GO:0030312,GO:0030497,GO:0032787,GO:0034440,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:0072330,GO:0075136,GO:1901575,GO:1901576 1.1.1.157 0.0000000000000000000000000000000000000000000002529 168.0
HFD3_k127_7109195_5 Peptidase dimerisation domain K01436 - - 0.0002316 45.0
HFD3_k127_7134723_0 PFAM Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit K00335,K05587 - 1.6.5.3 1.897e-245 766.0
HFD3_k127_7134723_1 Molybdopterin oxidoreductase Fe4S4 region K00336,K05299 - 1.17.1.10,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000001187 215.0
HFD3_k127_7134723_2 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334,K05586 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000001359 199.0
HFD3_k127_7134723_3 YhhN family - - - 0.0000000000000000000000000000000000000000000000000000168 197.0
HFD3_k127_7151000_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 460.0
HFD3_k127_7151000_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000276 270.0
HFD3_k127_7151000_2 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000000000000003518 150.0
HFD3_k127_7151846_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 460.0
HFD3_k127_7151846_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 462.0
HFD3_k127_7151846_2 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003513 374.0
HFD3_k127_7151846_3 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008847 329.0
HFD3_k127_7151846_5 Thioesterase superfamily - - - 0.00000000000000000000000000000000000001846 148.0
HFD3_k127_7151846_6 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000001138 141.0
HFD3_k127_7151846_7 - - - - 0.000000000000000000000000000293 123.0
HFD3_k127_7153993_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 5.085e-207 655.0
HFD3_k127_7153993_1 - - - - 0.000000000000000008741 94.0
HFD3_k127_7163997_0 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 416.0
HFD3_k127_7163997_1 Nucleotidyl transferase K00978 - 2.7.7.33 0.0000000000000000000000000000000000000001616 151.0
HFD3_k127_7163997_2 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.00000000001078 72.0
HFD3_k127_7176554_0 Hydantoinase/oxoprolinase K01473 - 3.5.2.14 2.967e-245 775.0
HFD3_k127_7176554_1 NADH oxidase K00219 - 1.3.1.34 5.229e-221 698.0
HFD3_k127_7176554_2 N-methylhydantoinase B acetone carboxylase alpha subunit K01474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0017168,GO:0034641,GO:0043603,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0071704,GO:1901564 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 473.0
HFD3_k127_7176554_3 Domain of unknown function (DUF4342) - - - 0.00000000000000000004554 92.0
HFD3_k127_7176554_4 PFAM Forkhead-associated protein - - - 0.0000000000000155 84.0
HFD3_k127_7176554_5 hydrocarbon binding protein (contains V4R domain) K07013 - - 0.0000000000007392 75.0
HFD3_k127_722265_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 1.162e-199 640.0
HFD3_k127_722265_1 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 311.0
HFD3_k127_722265_2 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.00000000000000000000000000000000000000000000000000000000000000008645 230.0
HFD3_k127_7234965_0 Heat shock 70 kDa protein K04043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 483.0
HFD3_k127_7234965_1 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008681 321.0
HFD3_k127_7234965_2 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000000000000000000000000000000001095 229.0
HFD3_k127_7234965_3 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000008661 160.0
HFD3_k127_7282745_0 ABC transporter, ATP-binding protein K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 375.0
HFD3_k127_7282745_1 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000002575 255.0
HFD3_k127_7282745_2 Domain of unknown function (DUF4037) - - - 0.0000000000000000000000000000000000000000000000000000000000000000002752 236.0
HFD3_k127_7282745_3 transport system permease component K01992 - - 0.000000000000000000000000000000000000000000000000000005985 200.0
HFD3_k127_7296465_0 Polysaccharide biosynthesis protein - - - 0.000000000000000000000005831 117.0
HFD3_k127_7296465_1 lipid-A-disaccharide synthase activity K00748 - 2.4.1.182 0.00000000003045 69.0
HFD3_k127_7301209_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009152 397.0
HFD3_k127_7301209_1 cytochrome c oxidase (Subunit II) K02275 - 1.9.3.1 0.00000000006796 73.0
HFD3_k127_7301209_2 Lactonase, 7-bladed beta-propeller - - - 0.000004162 58.0
HFD3_k127_7308808_0 Tricorn protease homolog K08676 - - 0.0 1274.0
HFD3_k127_7308808_1 Uncharacterized conserved protein (DUF2196) - - - 0.00000000000000005706 81.0
HFD3_k127_7362524_0 Dehydrogenase K00117 - 1.1.5.2 4.998e-307 955.0
HFD3_k127_7362524_1 GMC oxidoreductase - - - 3.06e-235 739.0
HFD3_k127_7362524_2 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 396.0
HFD3_k127_7362524_3 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 314.0
HFD3_k127_7362524_4 - - - - 0.0000000000000000000000000000000000000000000000000000007994 196.0
HFD3_k127_7362524_5 Cytochrome c - - - 0.0000000000000000000000000000000000001379 149.0
HFD3_k127_7362524_6 Gluconate 2-dehydrogenase subunit 3 K06152 - 1.1.99.3 0.0000000000000000000000000000000000002653 148.0
HFD3_k127_7362524_7 TIGRFAM endoribonuclease L-PSP - - - 0.00000000000000000000000000000000001461 142.0
HFD3_k127_7362524_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000005128 126.0
HFD3_k127_7378766_0 exo-alpha-(2->6)-sialidase activity K01186 GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509 3.2.1.18 1.397e-227 713.0
HFD3_k127_7378766_1 Belongs to the UbiD family K03182 - 4.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006199 596.0
HFD3_k127_7378766_10 Sulfate permease family K03321 - - 0.00000000000000000000000002626 118.0
HFD3_k127_7378766_11 Sulfate transporter antisigma-factor antagonist STAS K03321 - - 0.000000001028 62.0
HFD3_k127_7378766_2 involved in signal transduction (via phosphorylation) involved in transcriptional regulatory mechanism and in the regulation of secondary metabolites catalytic activity ATP a protein ADP a phosphoprotein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000467 585.0
HFD3_k127_7378766_3 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 422.0
HFD3_k127_7378766_4 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 341.0
HFD3_k127_7378766_5 ABC-type nitrate sulfonate bicarbonate transport system, periplasmic component K02051 - - 0.00000000000000000000000000000000000000000000000000000004083 208.0
HFD3_k127_7378766_6 COGs COG1670 Acetyltransferase including N-acetylase of ribosomal protein - - - 0.00000000000000000000000000000000000000000000000000002513 194.0
HFD3_k127_7378766_7 Belongs to the carbamoyltransferase HypF family K04656 - - 0.0000000000000000000000000000000000000000001003 167.0
HFD3_k127_7378766_8 Domain of unknown function (DUF4440) - - - 0.000000000000000000000000000004986 123.0
HFD3_k127_7378766_9 COGs COG0659 Sulfate permease and related transporter (MFS superfamily) K03321 - - 0.00000000000000000000000000849 116.0
HFD3_k127_7393276_0 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049,K15555 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004387 282.0
HFD3_k127_7393276_1 WD40 repeats - - - 0.00000000000000000000000000000000000000000000000000000001205 212.0
HFD3_k127_7393276_2 B-1 B cell differentiation - - - 0.000000000001588 73.0
HFD3_k127_7409057_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 371.0
HFD3_k127_7409057_1 Beta-eliminating lyase K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 285.0
HFD3_k127_7409057_2 - - - - 0.00000000000009333 74.0
HFD3_k127_7409057_3 YtxH-like protein - - - 0.00004968 51.0
HFD3_k127_7409057_4 - - - - 0.0004167 46.0
HFD3_k127_7416640_0 Sodium:sulfate symporter transmembrane region K03319,K09477,K11106,K14445 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 591.0
HFD3_k127_7416640_1 Isocitrate/isopropylmalate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 0.00000000000000000000000000000000000000000000000000000000000000000000000001505 255.0
HFD3_k127_7416640_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000816 140.0
HFD3_k127_7416640_3 - - - - 0.0000000000000000000000000001161 124.0
HFD3_k127_7416640_4 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000008845 117.0
HFD3_k127_7416640_5 helix_turn_helix, Lux Regulon - - - 0.00000000000000003563 88.0
HFD3_k127_7416640_6 PFAM KaiB domain K08481 - - 0.0000000000003626 76.0
HFD3_k127_7416640_7 Putative zinc-finger - - - 0.0000000004813 70.0
HFD3_k127_7417889_0 Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde K00656,K07540,K18427 - 2.3.1.54,4.1.1.83,4.1.99.11 1.291e-267 845.0
HFD3_k127_7417889_1 Fungal trichothecene efflux pump (TRI12) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 617.0
HFD3_k127_7417889_3 PFAM regulatory protein GntR HTH - - - 0.000000000000000000000000000000000001301 147.0
HFD3_k127_7417889_4 transcriptional activator domain - - - 0.00000000000000000000000000001205 127.0
HFD3_k127_7417889_5 Glycyl-radical enzyme activating protein family protein K04069 - 1.97.1.4 0.000000000000000000005131 94.0
HFD3_k127_7432055_0 GTP cyclohydrolase I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000105 280.0
HFD3_k127_7432055_1 Protein of unknown function (DUF1003) - - - 0.000000000000000000000000000000000000000009528 160.0
HFD3_k127_7432055_2 Belongs to the UPF0337 (CsbD) family - - - 0.00000000000003256 77.0
HFD3_k127_7432055_3 Belongs to the UPF0337 (CsbD) family - - - 0.00000000000155 69.0
HFD3_k127_7432055_4 response regulator - - - 0.000000004605 60.0
HFD3_k127_7467565_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 3.19e-254 797.0
HFD3_k127_7467565_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004955 313.0
HFD3_k127_7467565_2 Cytochrome c oxidase subunit III K02276,K02299 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000003324 214.0
HFD3_k127_7467565_3 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) - - - 0.000000000000000000000000000000000000000000000000000000004202 204.0
HFD3_k127_7467565_4 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.000000000000000000000000000000000000000000000000000000699 196.0
HFD3_k127_7467565_5 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.0000000000737 66.0
HFD3_k127_7490409_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 3.873e-282 889.0
HFD3_k127_7521820_0 LysM domain K03046,K03641,K08642 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 351.0
HFD3_k127_7521820_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 333.0
HFD3_k127_7521820_2 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.00000000000000002066 82.0
HFD3_k127_7521820_3 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000001594 59.0
HFD3_k127_7539772_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000001022 210.0
HFD3_k127_7539772_1 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis K03816 - 2.4.2.22 0.00000000000000000000000000000000000000000000000000000000001151 213.0
HFD3_k127_7539772_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042886,GO:0042887,GO:0043953,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.0000000000000000000000000009825 119.0
HFD3_k127_7539772_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000002217 64.0
HFD3_k127_7542597_0 Fungalysin/Thermolysin Propeptide Motif K08603 - 3.4.24.27 4.74e-322 1005.0
HFD3_k127_7542597_1 peptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 399.0
HFD3_k127_7542597_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 366.0
HFD3_k127_7542597_4 Sulfatase-modifying factor enzyme 1 - GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016667,GO:0016670,GO:0018158,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0120147,GO:1901564,GO:1903136 - 0.00000000000000000000000000000000000000000000000007462 196.0
HFD3_k127_7542597_5 rRNA binding K02926 - - 0.0000000000000000000000000000000000000002029 167.0
HFD3_k127_7542597_7 Necessary for formate dehydrogenase activity K02380 - - 0.000002515 51.0
HFD3_k127_7586256_0 Lysine 2,3-aminomutase K01843 - 5.4.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 512.0
HFD3_k127_7586256_1 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008067 494.0
HFD3_k127_7586256_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009118 273.0
HFD3_k127_7586256_3 PFAM TrkA-N domain protein K03499 - - 0.0000000000000000000000000000000000000000000000000000000000000000001188 237.0
HFD3_k127_7586256_4 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000001846 230.0
HFD3_k127_7586256_5 PFAM TrkA-N domain protein K03499 - - 0.000000000000000000000000000000000000000000001114 169.0
HFD3_k127_7586256_6 Amino acid permease K03294 - - 0.0000000000000000000261 96.0
HFD3_k127_7586256_7 Transcriptional regulator, TraR DksA family K06204 - - 0.0000000000000008636 81.0
HFD3_k127_76116_0 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 540.0
HFD3_k127_76116_1 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 493.0
HFD3_k127_76116_2 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004091 488.0
HFD3_k127_76116_3 Pyridoxal-phosphate dependent enzyme K17950 - 4.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001008 286.0
HFD3_k127_76116_4 PFAM PDZ DHR GLGF domain protein K03797 - 3.4.21.102 0.0000000000000000000000000005342 116.0
HFD3_k127_76116_5 Major Facilitator - - - 0.000000002436 59.0
HFD3_k127_7623362_0 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 407.0
HFD3_k127_7623362_1 NYN domain - - - 0.00000000000000000004359 101.0
HFD3_k127_7623362_2 PFAM glycoside hydrolase family 39 - - - 0.00000001143 59.0
HFD3_k127_7711010_0 PFAM carboxyl transferase K01969,K15052 - 2.1.3.15,6.4.1.3,6.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004244 559.0
HFD3_k127_7711010_1 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K09181 - - 0.0000000000000000001871 89.0
HFD3_k127_7720588_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 354.0
HFD3_k127_7720588_1 PFAM Methicillin resistance protein - - - 0.0000000000000000000000000000000000000003536 158.0
HFD3_k127_7720588_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.000000000000000000000000000000000004162 141.0
HFD3_k127_7720588_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000001086 123.0
HFD3_k127_7720588_4 Belongs to the complex I subunit 6 family K00339,K05578 - 1.6.5.3 0.00000000000000000000000005029 113.0
HFD3_k127_7752229_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1045.0
HFD3_k127_7752229_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 404.0
HFD3_k127_7752229_2 4Fe-4S ferredoxin K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005859 303.0
HFD3_k127_7752229_3 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000004623 213.0
HFD3_k127_7752229_4 Polysulfide reductase - - - 0.00000000000000000000000000000000000000000000000000007334 200.0
HFD3_k127_7752229_5 Pfam Zn-finger in ubiquitin-hydrolases and other protein K03455 - - 0.000000000000000000000000000000000000000000369 162.0
HFD3_k127_7752229_6 PFAM DoxX family protein K15977 - - 0.000000000000000000000000000000000000000003714 162.0
HFD3_k127_7752229_7 Protein of unknown function (DUF3175) - - - 0.0000000000000000000000000000003208 124.0
HFD3_k127_7752229_8 Lysylphosphatidylglycerol synthase TM region - - - 0.00000000000403 73.0
HFD3_k127_779271_0 2-methylcitrate dehydratase activity K01720 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019679,GO:0019752,GO:0030312,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046459,GO:0047547,GO:0050896,GO:0071704,GO:0071944,GO:0072329,GO:1901575 4.2.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 518.0
HFD3_k127_779271_1 PrpF protein K09788,K16514 - 5.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000002939 253.0
HFD3_k127_779271_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000001306 224.0
HFD3_k127_779271_3 Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions K02553 - - 0.00000000000000000000000000000000000000000000000000000002849 212.0
HFD3_k127_782162_0 Alpha amylase, catalytic domain - - - 0.0 1386.0
HFD3_k127_782162_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 6.017e-253 789.0
HFD3_k127_782162_10 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005114 384.0
HFD3_k127_782162_11 PFAM Ribonuclease BN-like family K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005603 358.0
HFD3_k127_782162_12 transferase activity, transferring acyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 358.0
HFD3_k127_782162_13 PFAM glycoside hydrolase, family 4 K07406 - 3.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004644 344.0
HFD3_k127_782162_14 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005554 335.0
HFD3_k127_782162_15 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007077 330.0
HFD3_k127_782162_16 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002177 271.0
HFD3_k127_782162_17 cellular response to dsDNA K07178 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000002036 254.0
HFD3_k127_782162_18 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000001882 263.0
HFD3_k127_782162_19 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000008865 235.0
HFD3_k127_782162_2 prohibitin homologues K07192 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 506.0
HFD3_k127_782162_20 cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000003488 230.0
HFD3_k127_782162_21 lipid binding - - - 0.000000000000000000000000000000000000000000000000000000000004617 218.0
HFD3_k127_782162_22 PFAM Methyltransferase type 12 - - - 0.000000000000000000000000000000000000000000000000000000004284 207.0
HFD3_k127_782162_23 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) - - - 0.000000000000000000000000000000000000000000000000000000008006 210.0
HFD3_k127_782162_25 KR domain K00065 - 1.1.1.127 0.0000000000000000000000000000000000000000000000009991 183.0
HFD3_k127_782162_26 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000003432 182.0
HFD3_k127_782162_27 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000004271 173.0
HFD3_k127_782162_28 60Kd inner membrane protein K03217 - - 0.00000000000000000000000000000000000002678 151.0
HFD3_k127_782162_29 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000135 149.0
HFD3_k127_782162_3 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 497.0
HFD3_k127_782162_30 Cupin domain - - - 0.00000000000000000000000000000005561 127.0
HFD3_k127_782162_31 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.000000000000000000000000000003742 125.0
HFD3_k127_782162_32 - - - - 0.0000000000000000000001443 100.0
HFD3_k127_782162_33 - - - - 0.00000000000000002236 89.0
HFD3_k127_782162_35 PGAP1-like protein - - - 0.0000003323 62.0
HFD3_k127_782162_36 Protein of unknown function (DUF2892) - - - 0.000001887 55.0
HFD3_k127_782162_37 Membrane protein implicated in regulation of membrane protease activity - - - 0.00004589 53.0
HFD3_k127_782162_4 ABC transporter K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005274 482.0
HFD3_k127_782162_5 Peptidase family M50 K06212,K06402 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005787 458.0
HFD3_k127_782162_6 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003597 447.0
HFD3_k127_782162_7 PFAM von Willebrand factor type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 421.0
HFD3_k127_782162_8 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 411.0
HFD3_k127_782162_9 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 385.0
HFD3_k127_782820_0 Conserved region in glutamate synthase K00265 - 1.4.1.13,1.4.1.14 3.242e-252 790.0
HFD3_k127_782820_1 glutamate synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 488.0
HFD3_k127_782820_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.0000000000000000000000000000000000000000000002281 169.0
HFD3_k127_790508_0 methyltransferase - - - 0.00000000000000000000000000000000000000000000000003788 199.0
HFD3_k127_790508_1 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000004824 171.0
HFD3_k127_790508_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000001564 159.0
HFD3_k127_790508_3 GDP-mannose 4,6 dehydratase K19180 - 1.1.1.339 0.000000000000000000000000000000001433 141.0
HFD3_k127_790508_4 Putative zinc binding domain - - - 0.0000000000000000000002402 99.0
HFD3_k127_7922_0 PFAM glycoside hydrolase family 65 central catalytic - - - 2.477e-278 873.0
HFD3_k127_7922_1 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 5.173e-226 706.0
HFD3_k127_7922_10 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.000000000001469 74.0
HFD3_k127_7922_2 [isocitrate dehydrogenase (NADP+)] phosphatase activity K00906 GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004721,GO:0004722,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009060,GO:0009987,GO:0015980,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0016999,GO:0017076,GO:0017144,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046487,GO:0050790,GO:0055114,GO:0065007,GO:0065009,GO:0070262,GO:0071704,GO:0072350,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000525 613.0
HFD3_k127_7922_3 Radical_SAM C-terminal domain K07739 - 2.3.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 567.0
HFD3_k127_7922_4 helix_turn _helix lactose operon repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007936 388.0
HFD3_k127_7922_5 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K01838 - 5.4.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008648 298.0
HFD3_k127_7922_6 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002171 253.0
HFD3_k127_7922_7 Protein involved in amylo-alpha-1,6-glucosidase activity and glycogen biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000003137 204.0
HFD3_k127_7922_8 methyltransferase activity K02169 - 2.1.1.197 0.0000000000000000000000000000000000000000001619 168.0
HFD3_k127_7922_9 lactate racemase activity K22373 - 5.1.2.1 0.000000000000000000000001069 103.0
HFD3_k127_792314_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004266 419.0
HFD3_k127_792314_1 PFAM Cytochrome c oxidase, subunit I K04561 - 1.7.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 411.0
HFD3_k127_792314_2 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000004056 224.0
HFD3_k127_792314_3 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.000000000000000000000000000000000000005518 147.0
HFD3_k127_792314_4 cytochrome c K02305 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000186 145.0
HFD3_k127_794117_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1024.0
HFD3_k127_794117_1 PFAM glycosyl transferase, family 51 - - - 1.114e-283 904.0
HFD3_k127_794117_10 PFAM Phosphoribosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000149 209.0
HFD3_k127_794117_11 Esterase lipase - - - 0.0000000000000000000000000000000000000000000000000000000005841 215.0
HFD3_k127_794117_12 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000001332 194.0
HFD3_k127_794117_13 Methyltransferase K08316 - 2.1.1.171 0.0000000000000000000000000000000000000000000000006045 181.0
HFD3_k127_794117_14 DNA catabolic process, exonucleolytic K07464 - 3.1.12.1 0.0000000000000000000000000000000000000001421 158.0
HFD3_k127_794117_15 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000000000004552 147.0
HFD3_k127_794117_16 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000000000000000000001346 111.0
HFD3_k127_794117_17 Polysaccharide deacetylase K22278 - 3.5.1.104 0.000000000000000000000006631 114.0
HFD3_k127_794117_18 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000002285 82.0
HFD3_k127_794117_19 Multicopper oxidase - - - 0.0000000000003787 81.0
HFD3_k127_794117_2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K01782,K07516 - 1.1.1.35,4.2.1.17,5.1.2.3 9.431e-279 878.0
HFD3_k127_794117_20 - - - - 0.00000000002257 67.0
HFD3_k127_794117_21 Chagasin family peptidase inhibitor I42 K14475 - - 0.000000003583 63.0
HFD3_k127_794117_22 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000003393 57.0
HFD3_k127_794117_23 SMART cellulose binding type IV K11751 - 3.1.3.5,3.6.1.45 0.00000843 58.0
HFD3_k127_794117_3 Belongs to the thiolase family K00632 - 2.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003432 551.0
HFD3_k127_794117_4 PFAM response regulator receiver K02282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006314 389.0
HFD3_k127_794117_5 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 308.0
HFD3_k127_794117_6 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000008661 243.0
HFD3_k127_794117_7 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000002381 218.0
HFD3_k127_794117_8 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000000001343 212.0
HFD3_k127_794117_9 PFAM Translin K07477 - - 0.000000000000000000000000000000000000000000000000000000000012 213.0
HFD3_k127_796617_0 Belongs to the binding-protein-dependent transport system permease family K10440,K10553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 338.0
HFD3_k127_796617_1 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 314.0
HFD3_k127_796617_2 ATPases associated with a variety of cellular activities K02056,K10545 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000008166 257.0
HFD3_k127_796617_3 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000000000000000000000000000000002304 219.0
HFD3_k127_796617_4 Periplasmic binding protein domain K10439 - - 0.0000000000000000000000002274 109.0
HFD3_k127_799807_0 FGGY family of carbohydrate kinases, C-terminal domain K00854 - 2.7.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 562.0
HFD3_k127_799807_1 PFAM Alcohol dehydrogenase, zinc-binding K00001 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004693 385.0
HFD3_k127_799807_10 phosphorelay signal transduction system - - - 0.0000000000001021 75.0
HFD3_k127_799807_11 Abortive infection protein K07052 - - 0.00006358 54.0
HFD3_k127_799807_12 PFAM peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.0001641 53.0
HFD3_k127_799807_2 - - - - 0.0000000000000000000000000000000000000000000000000000001111 203.0
HFD3_k127_799807_3 PFAM Pyridoxal-dependent decarboxylase K01634 - 4.1.2.27 0.0000000000000000000000000000000000000000000006206 169.0
HFD3_k127_799807_4 EamA-like transporter family - - - 0.000000000000000000000000000000000000001358 155.0
HFD3_k127_799807_5 Cys-tRNA(Pro) hydrolase activity K03976 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0043906,GO:0043907,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.00000000000000000000000000000000000009869 149.0
HFD3_k127_799807_6 4Fe-4S binding domain - - - 0.000000000000000000000000000001438 123.0
HFD3_k127_799807_7 Ethyl tert-butyl ether degradation - - - 0.000000000000000000000000001248 115.0
HFD3_k127_799807_8 Domain of unknown function (DUF309) K09763 - - 0.00000000000000000000000001675 113.0
HFD3_k127_799807_9 Pfam:DUF422 - - - 0.00000000000000000000000002374 122.0
HFD3_k127_800559_0 ADP binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 455.0
HFD3_k127_804956_0 Belongs to the glycosyl hydrolase 31 family K01811 - 3.2.1.177 0.000000000000000000000000000002725 138.0
HFD3_k127_804956_1 membrane - - - 0.00005527 51.0
HFD3_k127_806141_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009524 556.0
HFD3_k127_806141_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 419.0
HFD3_k127_806141_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 330.0
HFD3_k127_806141_3 manganese ion transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001392 277.0
HFD3_k127_811375_0 dipeptide transport K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 457.0
HFD3_k127_811375_1 nitrogen compound transport K02033 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 338.0
HFD3_k127_811375_2 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000001362 84.0
HFD3_k127_81264_0 PFAM acetyl-CoA hydrolase transferase K01067 - 3.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 579.0
HFD3_k127_81264_1 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005528 457.0
HFD3_k127_81264_10 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K00177 - 1.2.7.1,1.2.7.3 0.000000000000000000000000000000000000000000000000000000007065 205.0
HFD3_k127_81264_11 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000291 210.0
HFD3_k127_81264_12 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.000000000000000000000000000000000000000001567 163.0
HFD3_k127_81264_13 Acetoin dehydrogenase K04766 GO:0001101,GO:0003674,GO:0003824,GO:0006066,GO:0006355,GO:0006950,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0009056,GO:0009267,GO:0009605,GO:0009847,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010033,GO:0010034,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016407,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019152,GO:0019219,GO:0019222,GO:0019751,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0032502,GO:0033554,GO:0034077,GO:0034078,GO:0034311,GO:0034313,GO:0042149,GO:0042180,GO:0042182,GO:0042221,GO:0042594,GO:0042844,GO:0042846,GO:0043894,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0045013,GO:0045014,GO:0045149,GO:0045150,GO:0045892,GO:0045934,GO:0045990,GO:0046015,GO:0046164,GO:0046174,GO:0046677,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0055114,GO:0060255,GO:0061984,GO:0061985,GO:0061986,GO:0065007,GO:0070887,GO:0071229,GO:0071236,GO:0071310,GO:0071311,GO:0071496,GO:0071704,GO:0080090,GO:1901575,GO:1901615,GO:1901616,GO:1901700,GO:1901701,GO:1902652,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000299 155.0
HFD3_k127_81264_14 Uncharacterized conserved protein (DUF2249) - - - 0.000000000000000000000000001771 113.0
HFD3_k127_81264_15 Cytochrome c - - - 0.000000000000000000000004557 117.0
HFD3_k127_81264_16 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00176 - 1.2.7.3 0.000000000000000000000282 98.0
HFD3_k127_81264_17 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000235 104.0
HFD3_k127_81264_18 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000003082 83.0
HFD3_k127_81264_19 Lactonase, 7-bladed beta-propeller - - - 0.000000000000001609 90.0
HFD3_k127_81264_2 Pyruvate:ferredoxin oxidoreductase core domain II K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 443.0
HFD3_k127_81264_20 Rhodanese Homology Domain - - - 0.000000000000003431 82.0
HFD3_k127_81264_22 Outer membrane protein, 28Kda K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00006493 48.0
HFD3_k127_81264_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 365.0
HFD3_k127_81264_4 alanine dehydrogenase activity K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 360.0
HFD3_k127_81264_5 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003881 317.0
HFD3_k127_81264_6 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 322.0
HFD3_k127_81264_7 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 301.0
HFD3_k127_81264_8 histidine kinase HAMP region domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000001653 246.0
HFD3_k127_81264_9 Two component transcriptional regulator, winged helix family K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000006023 230.0
HFD3_k127_819424_0 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 421.0
HFD3_k127_819424_1 PFAM homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000005232 196.0
HFD3_k127_819424_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000007086 54.0
HFD3_k127_823767_0 PFAM aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 0.0 1116.0
HFD3_k127_823767_1 secondary active sulfate transmembrane transporter activity K03321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 609.0
HFD3_k127_823767_10 xanthine dehydrogenase activity K03519 - 1.2.5.3 0.000000000000000000000000000000000002984 148.0
HFD3_k127_823767_11 PFAM Archaeal ATPase K06921 - - 0.000000000000004503 88.0
HFD3_k127_823767_12 Two component regulator propeller - - - 0.0000000003314 74.0
HFD3_k127_823767_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 568.0
HFD3_k127_823767_3 PFAM VWA containing CoxE family protein K07161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 418.0
HFD3_k127_823767_4 PFAM ATPase associated with various cellular activities, AAA_5 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 396.0
HFD3_k127_823767_5 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 357.0
HFD3_k127_823767_6 COGs COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM CutM homologs K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 290.0
HFD3_k127_823767_7 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006766 288.0
HFD3_k127_823767_8 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000002422 244.0
HFD3_k127_823767_9 PFAM Archaeal ATPase - - - 0.000000000000000000000000000000000000001183 169.0
HFD3_k127_827043_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 1.716e-202 644.0
HFD3_k127_829143_0 PFAM FAD linked oxidase domain protein K00102 - 1.1.2.4 3.162e-240 761.0
HFD3_k127_829143_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005918 563.0
HFD3_k127_829143_2 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000006495 104.0
HFD3_k127_837465_0 PFAM transferase hexapeptide repeat containing protein K16881 - 2.7.7.13,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 533.0
HFD3_k127_837465_1 3'-5' exonuclease K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000000000001525 264.0
HFD3_k127_837465_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:0140096,GO:1901564 - 0.000000000000000001433 95.0
HFD3_k127_838946_0 cyclic nucleotide binding K01420 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 610.0
HFD3_k127_838946_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007058 382.0
HFD3_k127_838946_2 regulatory protein, arsR - - - 0.00000000000000000000000000000000000000000001122 168.0
HFD3_k127_838946_3 membrane - - - 0.0000000000000000000000000000000000007022 151.0
HFD3_k127_838946_4 DUF218 domain - - - 0.00000000000000000000000000000000002711 143.0
HFD3_k127_838946_5 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000003258 108.0
HFD3_k127_840825_0 E1-E2 ATPase K01531 - 3.6.3.2 1.296e-296 932.0
HFD3_k127_840825_1 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 400.0
HFD3_k127_840825_10 Hydrolase - - - 0.00000000000000000000000000000000001116 145.0
HFD3_k127_840825_11 Dimerisation domain - - - 0.00000000000000000000000000000007825 138.0
HFD3_k127_840825_12 Ferritin-like domain K03594 - 1.16.3.1 0.0000000000000000000201 97.0
HFD3_k127_840825_14 lactoylglutathione lyase activity K00941,K01724,K01759,K07032,K08234 - 2.7.1.49,2.7.4.7,4.2.1.96,4.4.1.5 0.000000000002489 74.0
HFD3_k127_840825_15 Cell wall-active antibiotics response 4TMS YvqF K11622 - - 0.00000000001778 72.0
HFD3_k127_840825_16 DinB superfamily - - - 0.000000001273 65.0
HFD3_k127_840825_2 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 312.0
HFD3_k127_840825_3 Protein of unknown function (DUF1211) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 294.0
HFD3_k127_840825_4 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001031 273.0
HFD3_k127_840825_5 Phenylacetic acid catabolic protein K02609 - 1.14.13.149 0.00000000000000000000000000000000000000000000000000000000000000000000000000484 261.0
HFD3_k127_840825_6 Secondary thiamine-phosphate synthase enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000002145 231.0
HFD3_k127_840825_7 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000001569 176.0
HFD3_k127_840825_8 EamA-like transporter family - - - 0.000000000000000000000000000000000000005408 156.0
HFD3_k127_840825_9 HAD-hyrolase-like K07025 - - 0.00000000000000000000000000000000000753 143.0
HFD3_k127_843397_0 PFAM Cytochrome c assembly protein K02198 - - 8.59e-204 655.0
HFD3_k127_843397_1 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000053 286.0
HFD3_k127_843397_2 cytochrome C - - - 0.00000000000000000000000000000000000000000005538 170.0
HFD3_k127_843397_3 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.0000000000000000000000000000000000000000001615 164.0
HFD3_k127_843397_4 Protein of unknown function with PCYCGC motif - - - 0.00000000000000000000005518 103.0
HFD3_k127_843397_5 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K02275 - 1.9.3.1 0.000000000000000000001212 101.0
HFD3_k127_843397_6 subunit of a heme lyase K02200 - - 0.00000000000000000009274 96.0
HFD3_k127_843397_7 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000002911 72.0
HFD3_k127_848933_0 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006022 317.0
HFD3_k127_848933_1 O-methyltransferase activity - - - 0.000000000000000000000000000000001146 133.0
HFD3_k127_848933_2 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000785 134.0
HFD3_k127_848933_3 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0000000000000000000000000001972 117.0
HFD3_k127_848933_4 Prokaryotic dksA/traR C4-type zinc finger - - - 0.0000000000000815 79.0
HFD3_k127_853784_0 Pyrimidine nucleoside phosphorylase C-terminal domain K00756,K00758 GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016757,GO:0016758,GO:0044424,GO:0044444,GO:0044464 2.4.2.2,2.4.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008578 494.0
HFD3_k127_853784_1 PFAM sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 462.0
HFD3_k127_853784_2 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000005087 140.0
HFD3_k127_855534_0 PFAM glycoside hydrolase, clan GH-D K07407 - 3.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 424.0
HFD3_k127_855534_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000002419 223.0
HFD3_k127_855534_2 positive regulation of growth K19687 - - 0.000000003122 69.0
HFD3_k127_868486_0 COG0747 ABC-type dipeptide transport system, periplasmic component K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007253 498.0
HFD3_k127_868486_1 Transports peptides consisting of two or three amino acids - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006478 277.0
HFD3_k127_868486_2 Transcriptional regulator IclR K13641 - - 0.0000000000000000000000000000000000000000000000000985 186.0
HFD3_k127_868486_3 methyltransferase activity - - - 0.000000000000000000002393 95.0
HFD3_k127_872907_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 580.0
HFD3_k127_872907_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 387.0
HFD3_k127_872907_2 alpha-ribazole phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000001137 223.0
HFD3_k127_872907_3 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000001392 175.0
HFD3_k127_872907_4 Protein of unknown function (DUF421) - - - 0.00000000000000000000000000000000000000004598 160.0
HFD3_k127_872907_5 PBS lyase HEAT-like repeat - - - 0.0000000000000000000000000000005294 134.0
HFD3_k127_872907_6 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000805 80.0
HFD3_k127_873914_0 PFAM Integrase catalytic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003078 370.0
HFD3_k127_873914_1 Protein of unknown function (DUF541) K09807 - - 0.00000000000000000000000000000003233 135.0
HFD3_k127_873914_2 PFAM NADH-Ubiquinone plastoquinone (complex I), various chains K00342,K05568 - 1.6.5.3 0.000351 53.0
HFD3_k127_891320_0 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 1.515e-220 701.0
HFD3_k127_891320_1 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004434 409.0
HFD3_k127_891320_10 - - - - 0.00004446 49.0
HFD3_k127_891320_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 378.0
HFD3_k127_891320_3 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000008804 226.0
HFD3_k127_891320_4 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K00330 - 1.6.5.3 0.00000000000000000000000000000000000001148 147.0
HFD3_k127_891320_5 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000002506 145.0
HFD3_k127_891320_6 PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000000000000000000003925 142.0
HFD3_k127_891320_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000000001967 123.0
HFD3_k127_891320_8 4-vinyl reductase, 4VR - - - 0.00000000000000000003869 98.0
HFD3_k127_891320_9 DinB superfamily - - - 0.00002368 54.0
HFD3_k127_892275_0 PFAM Pyruvate phosphate dikinase, PEP K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009193 383.0
HFD3_k127_892275_1 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006401 276.0
HFD3_k127_892275_2 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002105 270.0
HFD3_k127_892275_3 Phosphoglycerate mutase family K15634 - 5.4.2.12 0.0004005 46.0
HFD3_k127_90433_0 Sarcosine oxidase, gamma subunit family K19191 GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0005488,GO:0005542,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006520,GO:0006575,GO:0006576,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008480,GO:0009056,GO:0009063,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016491,GO:0016645,GO:0019695,GO:0019752,GO:0019842,GO:0031406,GO:0031974,GO:0033218,GO:0034641,GO:0035999,GO:0036094,GO:0042133,GO:0042135,GO:0042219,GO:0042402,GO:0042426,GO:0042558,GO:0043167,GO:0043168,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0046483,GO:0046653,GO:0046997,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0055114,GO:0065007,GO:0065008,GO:0070013,GO:0071704,GO:0072341,GO:0097159,GO:0097164,GO:1901052,GO:1901053,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.5.3.19 3.135e-259 822.0
HFD3_k127_90433_1 phosphatase activity K07025,K20866 - 3.1.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001895 280.0
HFD3_k127_90433_2 Choline/ethanolamine kinase - - - 0.000000000000000000000000000000001181 135.0
HFD3_k127_90433_3 ergothioneine biosynthetic process K01919,K06048 - 6.3.2.2 0.00000000000000000000000000006527 122.0
HFD3_k127_904803_0 PFAM Acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 577.0
HFD3_k127_904803_1 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 426.0
HFD3_k127_904803_11 Major facilitator Superfamily - - - 0.00000000005321 74.0
HFD3_k127_904803_12 Bacterial transcription activator, effector binding domain K13652 - - 0.000002563 57.0
HFD3_k127_904803_2 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008977 388.0
HFD3_k127_904803_3 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005592 277.0
HFD3_k127_904803_4 Haem-binding domain - - - 0.000000000000000000000000000000000000000000000000001038 186.0
HFD3_k127_904803_5 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000006947 192.0
HFD3_k127_904803_6 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000004104 179.0
HFD3_k127_904803_7 Domain of unknown function (DUF3786) - - - 0.00000000000000000000000000008168 123.0
HFD3_k127_904803_8 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.000000000000000000000000003043 115.0
HFD3_k127_904803_9 YwiC-like protein - - - 0.0000000000001466 81.0
HFD3_k127_907021_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 5.344e-274 862.0
HFD3_k127_907021_1 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 450.0
HFD3_k127_907021_2 protease-associated PA domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005634 455.0
HFD3_k127_907021_3 dipeptide transport K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 416.0
HFD3_k127_907021_4 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 383.0
HFD3_k127_907021_5 Cation transporter/ATPase, N-terminus K01531,K01535,K01537,K12952 - 3.6.3.2,3.6.3.6,3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004973 301.0
HFD3_k127_907021_6 succinylglutamate desuccinylase aspartoacylase K06987 - - 0.000000000000000000000000000000000000000000000000000000000000000001125 239.0
HFD3_k127_907021_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000001081 122.0
HFD3_k127_912635_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 2.567e-212 668.0
HFD3_k127_912635_1 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000003269 165.0
HFD3_k127_912635_2 TIGRFAM NADH-quinone oxidoreductase, chain G K00336 - 1.6.5.3 0.000000000000000000000000000000000004352 138.0
HFD3_k127_91525_0 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009563 369.0
HFD3_k127_91525_1 phosphatidylinositol kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001478 267.0
HFD3_k127_91525_2 alpha-ribazole phosphatase activity K02226,K15634,K22305 - 3.1.3.3,3.1.3.73,5.4.2.12 0.000000000000000000000000000000000000000000000000000000000155 221.0
HFD3_k127_91525_3 Protein of unknown function (DUF3090) - - - 0.00000000000000000000000000000000000000000001265 179.0
HFD3_k127_91525_4 nUDIX hydrolase - GO:0003674,GO:0003824,GO:0016787,GO:0016817,GO:0016818 - 0.00000000000000000000000000000000000009869 149.0
HFD3_k127_91525_5 transposition K07497 - - 0.00000000000000000000001133 105.0
HFD3_k127_91525_6 transposition K07497 - - 0.0007843 43.0
HFD3_k127_918830_0 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 415.0
HFD3_k127_918830_1 carnitine dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 375.0
HFD3_k127_918830_10 GAF domain - - - 0.0002215 51.0
HFD3_k127_918830_2 Thiolase, C-terminal domain K00626,K07508 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005265 368.0
HFD3_k127_918830_3 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005415 307.0
HFD3_k127_918830_4 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000004816 248.0
HFD3_k127_918830_5 YsiA-like protein, C-terminal region - - - 0.00000000000000000000000000000000000000000000207 172.0
HFD3_k127_918830_6 S-adenosyl methyltransferase - - - 0.000000000000000000000000000000000000008616 158.0
HFD3_k127_918830_8 X-Pro dipeptidyl-peptidase (S15 family) K06889 - - 0.00000000000000000001001 102.0
HFD3_k127_918830_9 Redoxin K03564 - 1.11.1.15 0.0000001995 58.0
HFD3_k127_930549_0 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000444 575.0
HFD3_k127_930549_1 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005191 520.0
HFD3_k127_930549_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006077 497.0
HFD3_k127_930549_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 418.0
HFD3_k127_930549_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000002731 257.0
HFD3_k127_933283_0 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002802 474.0
HFD3_k127_933283_1 Peptidase family M28 K19701 - 3.4.11.10,3.4.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000005074 275.0
HFD3_k127_933283_2 Response regulator receiver K02479,K07692 - - 0.00000000000000000000002687 104.0
HFD3_k127_933321_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 553.0
HFD3_k127_933321_1 - - - - 0.00000000006576 63.0
HFD3_k127_940939_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 467.0
HFD3_k127_940939_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703,K20452 - 4.2.1.33,4.2.1.35,4.2.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009421 406.0
HFD3_k127_940939_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000008631 57.0
HFD3_k127_952982_0 - - - - 0.0000000000000000000000000000000000000000000001241 179.0
HFD3_k127_952982_1 - - - - 0.000000000000000000000000000000000462 142.0
HFD3_k127_952982_2 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000001645 136.0
HFD3_k127_952982_3 CAAX protease self-immunity K07052 - - 0.000000000000000000000000006308 119.0
HFD3_k127_952982_4 Beta-lactamase class C and other penicillin binding proteins - - - 0.000007932 53.0
HFD3_k127_95842_0 - - - - 0.00000000000000000000000000000000000000000000003007 185.0
HFD3_k127_95842_1 Methyltransferase type 12 - - - 0.00000000000000000000000000000000000000000000004426 179.0
HFD3_k127_965071_0 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 517.0
HFD3_k127_965071_1 lactate metabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005714 361.0
HFD3_k127_965071_2 Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001726 282.0
HFD3_k127_972796_0 ABC-Type Dipeptide Transport System Periplasmic Component K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 322.0
HFD3_k127_972796_1 COG3119 Arylsulfatase A and related enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005384 258.0
HFD3_k127_972796_2 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000006347 222.0
HFD3_k127_972796_3 KduI/IolB family K03337 - 5.3.1.30 0.00000000000000000000000000000000000000000352 164.0
HFD3_k127_988370_0 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000000004986 144.0
HFD3_k127_988370_2 helix_turn_helix, Lux Regulon K11618 - - 0.000000000000000000000000000000004329 134.0
HFD3_k127_988370_3 PFAM peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.000000000000000000000000009943 111.0
HFD3_k127_988370_4 Acid phosphatase homologues K19302 - 3.6.1.27 0.0000000000000000000000317 110.0
HFD3_k127_999956_0 TIGRFAM methylmalonyl-CoA mutase, large subunit K01848 - 5.4.99.2 1.195e-257 805.0
HFD3_k127_999956_1 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 1.59e-227 715.0
HFD3_k127_999956_10 Glyoxalase-like domain K01759,K05606 - 4.4.1.5,5.1.99.1 0.000000000000000000000000000000000000001045 151.0
HFD3_k127_999956_11 CoA carboxylase activity K01965,K02160 - 6.4.1.3 0.0000000000000000000000000000005043 128.0
HFD3_k127_999956_12 Rieske-like [2Fe-2S] domain K05710 - - 0.0000000000000000000000003126 108.0
HFD3_k127_999956_13 TfoX N-terminal domain - - - 0.0000000000000000000001029 102.0
HFD3_k127_999956_14 PFAM Methyltransferase type 11 - - - 0.00000000000000000002939 100.0
HFD3_k127_999956_15 Domain of unknown function (DU1801) - - - 0.00000000000002598 78.0
HFD3_k127_999956_2 Carbamoyl-phosphate synthetase large chain domain protein K01961,K01968,K11263 - 6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4 6.69e-208 658.0
HFD3_k127_999956_3 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009537 457.0
HFD3_k127_999956_4 proline dipeptidase activity K01271 - 3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 451.0
HFD3_k127_999956_5 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 379.0
HFD3_k127_999956_6 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004647 299.0
HFD3_k127_999956_7 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008491 282.0
HFD3_k127_999956_8 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000524 223.0
HFD3_k127_999956_9 TIGRFAM SUF system FeS assembly protein, NifU family K04488 - - 0.0000000000000000000000000000000000000000000000002126 183.0