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Overview

ID MAG01681
Name HFD3_bin.20
Sample SMP0045
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Vicinamibacteria
Order Vicinamibacterales
Family 2-12-FULL-66-21
Genus
Species
Assembly information
Completeness (%) 77.61
Contamination (%) 2.84
GC content (%) 70.0
N50 (bp) 12,783
Genome size (bp) 4,341,119

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3481

Gene name Description KEGG GOs EC E-value Score Sequence
HFD3_k127_100023_0 alpha amylase catalytic K01182,K05343 - 3.2.1.1,3.2.1.10,5.4.99.16 4.644e-301 942.0
HFD3_k127_1008051_0 Sortilin, neurotensin receptor 3, - - - 0.0 1163.0
HFD3_k127_1008051_1 Cytidine monophosphokinase K00876 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000005966 258.0
HFD3_k127_1008051_2 2-phosphosulpholactate phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000001251 220.0
HFD3_k127_1008051_3 dUTP diphosphatase activity K01520,K13038 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0022607,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0051259,GO:0051260,GO:0055086,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23,4.1.1.36,6.3.2.5 0.00000000000000000000000000000002284 134.0
HFD3_k127_1008051_4 MacB-like periplasmic core domain - - - 0.000000000000000000000008838 105.0
HFD3_k127_1008051_5 deoxyribonucleoside 5'-monophosphate N-glycosidase activity K09457 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009123,GO:0009125,GO:0009159,GO:0009162,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070694,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 1.7.1.13 0.0000000000000003895 85.0
HFD3_k127_1008051_6 - - - - 0.0000002647 61.0
HFD3_k127_1017461_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 6.4e-262 827.0
HFD3_k127_1017461_1 FtsX-like permease family K02004 - - 2.566e-236 760.0
HFD3_k127_1017461_10 DoxX - - - 0.0000005439 53.0
HFD3_k127_1017461_11 Protein of unknown function (DUF3795) - - - 0.000002543 54.0
HFD3_k127_1017461_2 efflux transmembrane transporter activity - - - 4.198e-197 656.0
HFD3_k127_1017461_3 abc transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 343.0
HFD3_k127_1017461_4 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002877 325.0
HFD3_k127_1017461_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 331.0
HFD3_k127_1017461_6 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 314.0
HFD3_k127_1017461_7 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000002131 194.0
HFD3_k127_1017461_8 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000003545 128.0
HFD3_k127_1017461_9 Ribosomal protein L7/L12 C-terminal domain - - - 0.0000000001896 66.0
HFD3_k127_104231_0 Angiotensin-converting enzyme K01283 - 3.4.15.1 8.73e-259 814.0
HFD3_k127_104231_1 enterobactin catabolic process K07214,K09689 - 3.6.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 490.0
HFD3_k127_104231_10 - - - - 0.000174 53.0
HFD3_k127_104231_2 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004407 467.0
HFD3_k127_104231_3 Beta-L-arabinofuranosidase, GH127 K09955 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004185 433.0
HFD3_k127_104231_4 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001248 279.0
HFD3_k127_104231_5 methyltransferase activity K02169 - 2.1.1.197 0.000000000000000000000000000000000000000000000000000007369 198.0
HFD3_k127_104231_6 DNA repair - GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0032259,GO:0034641,GO:0036260,GO:0036261,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071164,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.00000000000000000000002159 109.0
HFD3_k127_104231_7 oxidoreductase activity - - - 0.0000000000002409 83.0
HFD3_k127_104231_8 photosystem II stabilization K02237,K02719 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0009521,GO:0009523,GO:0009579,GO:0016020,GO:0030075,GO:0030096,GO:0032991,GO:0034357,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044425,GO:0044436,GO:0044444,GO:0044459,GO:0044464,GO:0071944,GO:0098796,GO:0098797 - 0.00000000001702 77.0
HFD3_k127_104231_9 serine-type endopeptidase activity - - - 0.00000001746 63.0
HFD3_k127_1057490_0 PFAM Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 512.0
HFD3_k127_1057490_1 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001448 293.0
HFD3_k127_1057490_2 Dihydrodipicolinate reductase, N-terminus K21672 - 1.4.1.12,1.4.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001627 300.0
HFD3_k127_1057490_3 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000004851 237.0
HFD3_k127_1063360_0 Dienelactone hydrolase family - - - 0.0 1184.0
HFD3_k127_1063360_1 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 441.0
HFD3_k127_1063360_2 Peptidase MA superfamily - - - 0.00000000000000000000000000000000002134 150.0
HFD3_k127_1063360_3 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000001815 100.0
HFD3_k127_1063360_4 - - - - 0.000000000000000001183 97.0
HFD3_k127_1063360_5 Class III cytochrome C family - - - 0.000000000002812 73.0
HFD3_k127_1081916_0 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009114 602.0
HFD3_k127_1081916_1 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000006694 248.0
HFD3_k127_1081916_2 Secretin and TonB N terminus short domain K02666 - - 0.0000000000000000000000000000000000000000000000000000004109 200.0
HFD3_k127_1081916_3 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000007761 142.0
HFD3_k127_1081916_4 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000009349 136.0
HFD3_k127_1081916_5 protein contain chitin-binding domain type 3 K01183,K21606 - 3.2.1.14,3.2.1.202 0.00000000000000000000000001678 121.0
HFD3_k127_1081916_7 Tetratricopeptide repeats - - - 0.0000000004159 72.0
HFD3_k127_1092693_0 Amidase K01426 - 3.5.1.4 7.796e-217 687.0
HFD3_k127_1092693_1 Phosphoribosyl transferase domain K07100 - - 0.000000000000000000000000000000000000000000000000000000000000007185 220.0
HFD3_k127_1092693_2 - - - - 0.0000000000000000000000000007823 126.0
HFD3_k127_1092693_3 Rhodanese-like domain - - - 0.00000002369 57.0
HFD3_k127_1111503_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 8.577e-205 660.0
HFD3_k127_1111503_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005726 586.0
HFD3_k127_1111503_2 Radical SAM superfamily K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008686 452.0
HFD3_k127_1111503_3 PFAM Aminotransferase class I and II K00812,K10907 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 328.0
HFD3_k127_1111503_4 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000001098 206.0
HFD3_k127_1111503_5 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.000000000000000000000000000000000000299 146.0
HFD3_k127_1111503_6 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000001383 134.0
HFD3_k127_1111503_7 CoA-binding protein K06929 - - 0.0000000000000000000000003256 121.0
HFD3_k127_1120762_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.426e-282 912.0
HFD3_k127_1120762_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 3.481e-237 747.0
HFD3_k127_1120762_10 ABC-2 type transporter K09690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006998 259.0
HFD3_k127_1120762_11 spore germination - - - 0.000000000000000000000000000000000000000000000000000000000000004204 230.0
HFD3_k127_1120762_12 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000002164 210.0
HFD3_k127_1120762_13 Beta-lactamase K17836 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000005724 207.0
HFD3_k127_1120762_14 SMART Transcription regulator, AsnC-type K03718,K03719 - - 0.00000000000000000000000000000000000000000000006165 174.0
HFD3_k127_1120762_15 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000001167 177.0
HFD3_k127_1120762_16 Sigma-70 region 3 K02405 - - 0.0000000000000000000000000000000000001095 154.0
HFD3_k127_1120762_17 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000006542 147.0
HFD3_k127_1120762_18 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000001313 137.0
HFD3_k127_1120762_19 Peptidylprolyl isomerase K03771 - 5.2.1.8 0.00000000000000000000000000000003699 139.0
HFD3_k127_1120762_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.469e-232 728.0
HFD3_k127_1120762_20 Transcription termination factor nusG - - - 0.00000000000000000000000000000007719 142.0
HFD3_k127_1120762_21 PDZ DHR GLGF domain protein - - - 0.000000000000000000000000000000165 134.0
HFD3_k127_1120762_22 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000982 72.0
HFD3_k127_1120762_23 Protein of unknown function with PCYCGC motif - - - 0.000000001902 68.0
HFD3_k127_1120762_24 - - - - 0.0000007673 59.0
HFD3_k127_1120762_25 Stress responsive A/B Barrel Domain - - - 0.00001248 53.0
HFD3_k127_1120762_26 Protein of unknown function with PCYCGC motif - - - 0.0005401 43.0
HFD3_k127_1120762_3 ATPases associated with a variety of cellular activities K01990,K09689,K09691,K09693 - 3.6.3.38,3.6.3.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003583 472.0
HFD3_k127_1120762_4 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009206 434.0
HFD3_k127_1120762_5 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 388.0
HFD3_k127_1120762_6 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006305 312.0
HFD3_k127_1120762_7 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 291.0
HFD3_k127_1120762_8 histidine kinase A domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001696 296.0
HFD3_k127_1120762_9 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000371 270.0
HFD3_k127_1168729_0 S-adenosylmethionine synthetase, C-terminal domain K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008628 570.0
HFD3_k127_1168729_1 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 296.0
HFD3_k127_1168729_2 recombinase XerD K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000172 284.0
HFD3_k127_1168729_3 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004452 290.0
HFD3_k127_1168729_4 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K02564 - 3.5.99.6 0.0000000000000000000000000000000000000000000000000000000000000000001671 253.0
HFD3_k127_1168729_5 BadF/BadG/BcrA/BcrD ATPase family - GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006040,GO:0006044,GO:0006082,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0045127,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901071,GO:1901135,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000002253 208.0
HFD3_k127_1168729_6 PHP domain protein - - - 0.00000000000000000000000001421 125.0
HFD3_k127_1168729_7 Domain of unknown function (DUF4342) - - - 0.0000008879 56.0
HFD3_k127_11735_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009298 373.0
HFD3_k127_11735_1 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.00000000000000000000031 106.0
HFD3_k127_11735_2 cheY-homologous receiver domain K02657 - - 0.00000000000000001983 96.0
HFD3_k127_1194563_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003154 297.0
HFD3_k127_1194563_1 Beta-lactamase K01256,K17836 - 3.4.11.2,3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000002834 256.0
HFD3_k127_1194563_2 major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000001 195.0
HFD3_k127_1194563_3 Flavin containing amine oxidoreductase K00274 - 1.4.3.4 0.0000000000000000000000000000000000000000000000001852 194.0
HFD3_k127_1194563_5 PFAM Adenylate and Guanylate cyclase catalytic domain - - - 0.0000001851 63.0
HFD3_k127_1194563_6 - - - - 0.0000003634 59.0
HFD3_k127_128364_0 Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007429 506.0
HFD3_k127_128364_1 Oxidoreductase family, C-terminal alpha beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001161 240.0
HFD3_k127_128364_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000002154 222.0
HFD3_k127_128364_3 Beta-lactamase - - - 0.000000000000000000000000000000000000000001003 170.0
HFD3_k127_128364_4 - - - - 0.000000000000000000000000000000000001886 141.0
HFD3_k127_128364_6 - - - - 0.00000000000000000000000000001147 121.0
HFD3_k127_128364_8 Polymer-forming cytoskeletal - - - 0.00000000000000004215 87.0
HFD3_k127_1285377_0 efflux transmembrane transporter activity - - - 2.03e-322 1005.0
HFD3_k127_1285377_1 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 616.0
HFD3_k127_1285377_2 PFAM Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004043 508.0
HFD3_k127_1285377_3 CBD_II K19668 - 3.2.1.91 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 442.0
HFD3_k127_1285377_4 HAMP domain K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005894 432.0
HFD3_k127_1285377_5 4Fe-4S dicluster domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 355.0
HFD3_k127_1285377_6 Glycosyl hydrolase-like 10 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 344.0
HFD3_k127_1285377_7 Glycine cleavage H-protein - - - 0.0000000000000000000000000000000000000000000000000000001996 202.0
HFD3_k127_1285377_8 Peptidase family M54 K06974 - - 0.00000000000000000000000000000000000000001692 159.0
HFD3_k127_1285377_9 Glycine cleavage H-protein - - - 0.0000000000000000000000000000002752 132.0
HFD3_k127_1294767_0 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005745 370.0
HFD3_k127_1294767_1 Belongs to the MlaE permease family K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002127 253.0
HFD3_k127_1294767_2 PFAM ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001753 246.0
HFD3_k127_1294767_3 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.000000000000000000000000000000000000000000000000000009831 207.0
HFD3_k127_1294767_4 Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state - - - 0.00000000000000000000000000000000000000000000767 173.0
HFD3_k127_1294767_5 Virulence factor BrkB K07058 - - 0.0000000000000000002679 100.0
HFD3_k127_1294767_6 YtxH-like protein - - - 0.0000005821 61.0
HFD3_k127_1294767_7 Rieske [2Fe-2S] domain - - - 0.000002095 50.0
HFD3_k127_129569_0 Sortilin, neurotensin receptor 3, - - - 0.0 1312.0
HFD3_k127_129569_1 C-terminal, D2-small domain, of ClpB protein K03694 - - 4.574e-270 856.0
HFD3_k127_129569_2 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 297.0
HFD3_k127_129569_3 Methionine aminopeptidase K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000002383 213.0
HFD3_k127_129569_4 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000000000000000000003885 122.0
HFD3_k127_129569_5 Protein conserved in bacteria - - - 0.0000000000000000000001713 108.0
HFD3_k127_129569_6 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000003035 96.0
HFD3_k127_1307462_0 Succinyl-CoA ligase like flavodoxin domain - - - 5.252e-202 651.0
HFD3_k127_1307462_1 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000625 140.0
HFD3_k127_1335809_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 1.351e-306 956.0
HFD3_k127_1335809_1 Peptidase family M28 - - - 1.029e-300 959.0
HFD3_k127_1335809_10 Protein tyrosine kinase - - - 0.0000000001036 71.0
HFD3_k127_1335809_11 Glycogen debranching enzyme K05988 - 3.2.1.11 0.00000000167 69.0
HFD3_k127_1335809_12 - - - - 0.000004427 54.0
HFD3_k127_1335809_2 Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde K00656,K20038 - 2.3.1.54,4.3.99.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 548.0
HFD3_k127_1335809_3 InterPro IPR010496 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 433.0
HFD3_k127_1335809_4 alpha beta - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 407.0
HFD3_k127_1335809_5 YCII-related domain - - - 0.00000000000000000000000000000000000000000000004332 178.0
HFD3_k127_1335809_6 alpha beta - - - 0.0000000000000000000000000000000000000000000009306 168.0
HFD3_k127_1335809_7 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000009857 164.0
HFD3_k127_1335809_8 Beta-L-arabinofuranosidase, GH127 K09955 - - 0.0000000000000397 84.0
HFD3_k127_1335809_9 Protein of unknown function (DUF4241) - - - 0.00000000005673 72.0
HFD3_k127_1384992_0 Alpha amylase, catalytic domain - - - 2.284e-273 874.0
HFD3_k127_1384992_1 4-alpha-D-((1- 4)-alpha-D-glucano)trehalose trehalohydrolase K01236 - 3.2.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003092 535.0
HFD3_k127_1384992_2 DNA polymerase LigD polymerase domain K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 445.0
HFD3_k127_1384992_3 Maltogenic Amylase, C-terminal domain K05343 - 3.2.1.1,5.4.99.16 0.0000000000000000000000000000000000000000000000000005068 190.0
HFD3_k127_1384992_4 Nucleotidyltransferase domain - - - 0.00000000000000000000000000000000000000000000000008347 189.0
HFD3_k127_1384992_5 PFAM DNA methylase N-4 N-6 K07316 - 2.1.1.72 0.0000000000000000000000000000003796 134.0
HFD3_k127_1384992_6 Type III restriction enzyme, res subunit K01156 - 3.1.21.5 0.00000745 54.0
HFD3_k127_1384992_7 Type III restriction enzyme res subunit K01156 - 3.1.21.5 0.00006445 51.0
HFD3_k127_1406655_0 peptidase S9B dipeptidylpeptidase IV domain protein - - - 4.813e-314 979.0
HFD3_k127_1406655_1 domain protein - - - 2.039e-256 829.0
HFD3_k127_1406655_2 radical SAM domain protein K22318 - - 5.024e-229 736.0
HFD3_k127_1406655_3 membrane protein, TerC K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 382.0
HFD3_k127_1406655_4 PFAM Hemerythrin HHE cation binding domain K09155 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 352.0
HFD3_k127_1406655_5 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000001156 152.0
HFD3_k127_1406655_6 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000008457 139.0
HFD3_k127_1406655_7 Protein of unknown function (DUF1697) - - - 0.000000000000000000000005633 107.0
HFD3_k127_1406655_8 tryptophan 2,3-dioxygenase activity K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11 0.0000000000000003995 83.0
HFD3_k127_1406655_9 Photosynthesis system II assembly factor YCF48 - - - 0.000000009065 67.0
HFD3_k127_1435094_0 transposition - - - 0.00000000000000000000000000000000000000000000000000000000000001407 242.0
HFD3_k127_1454301_0 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000001379 247.0
HFD3_k127_1454301_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000002639 192.0
HFD3_k127_1454301_2 Cytochrome C and Quinol oxidase polypeptide I K02274 - 1.9.3.1 0.0000000000000000000000000001754 116.0
HFD3_k127_1454301_3 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.00000000000000000000008092 101.0
HFD3_k127_1456542_0 Glycosyl hydrolase 36 superfamily, catalytic domain K00702,K13688 - 2.4.1.20 0.0 3161.0
HFD3_k127_1456542_1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 2.114e-264 832.0
HFD3_k127_1456542_10 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000000000000008355 133.0
HFD3_k127_1456542_12 lipolytic protein G-D-S-L family - - - 0.000000000000000000000005001 120.0
HFD3_k127_1456542_13 lipocalin K03098 - - 0.0000000000000000005752 87.0
HFD3_k127_1456542_14 YHS domain - - - 0.0000000000003019 70.0
HFD3_k127_1456542_2 efflux transmembrane transporter activity - - - 2.34e-216 704.0
HFD3_k127_1456542_3 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000496 479.0
HFD3_k127_1456542_4 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006657 445.0
HFD3_k127_1456542_5 Integral membrane sensor signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003675 325.0
HFD3_k127_1456542_6 TIGRFAM glutaredoxin-like domain protein - - - 0.000000000000000000000000000000000000000000000000000000001445 224.0
HFD3_k127_1456542_7 Glycosyl hydrolases family 43 - - - 0.0000000000000000000000000000000000000000000000000000001725 194.0
HFD3_k127_1456542_8 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 GO:0002097,GO:0002100,GO:0003674,GO:0003824,GO:0004000,GO:0005488,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008251,GO:0008270,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0052717,GO:0071704,GO:0090304,GO:1901360 3.5.4.33 0.00000000000000000000000000000000000000000000000000002945 191.0
HFD3_k127_1456542_9 methyltransferase - - - 0.000000000000000000000000000000000002315 144.0
HFD3_k127_1472652_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 3.799e-251 782.0
HFD3_k127_1472652_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 2.303e-196 621.0
HFD3_k127_1472652_2 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006683 500.0
HFD3_k127_1472652_3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001444 290.0
HFD3_k127_1472652_4 fumarylacetoacetate (FAA) hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001522 258.0
HFD3_k127_1472652_5 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016787,GO:0017076,GO:0019538,GO:0019904,GO:0022607,GO:0030163,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0051603,GO:0065003,GO:0070003,GO:0070011,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000002475 234.0
HFD3_k127_1472652_6 WD domain, G-beta repeat K12132 - 2.7.11.1 0.000000000000000000000000000000002269 150.0
HFD3_k127_1472652_7 Fibronectin type III domain protein - - - 0.0000002852 63.0
HFD3_k127_1472652_9 - - - - 0.000572 52.0
HFD3_k127_1561872_0 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005882 256.0
HFD3_k127_1561872_1 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000002971 159.0
HFD3_k127_156662_0 PFAM Cys Met metabolism K01760,K01761 - 4.4.1.11,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 488.0
HFD3_k127_156662_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004821 422.0
HFD3_k127_156662_10 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000001259 247.0
HFD3_k127_156662_11 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K01142,K10773 GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006289,GO:0006296,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033683,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2,4.2.99.18 0.00000000000000000000000000000000000000000000000000000003342 206.0
HFD3_k127_156662_12 ethanolamine catabolic process K04027 - - 0.00000000000000000000000000000000000006421 143.0
HFD3_k127_156662_13 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.000000000000000000000000000000000397 138.0
HFD3_k127_156662_14 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028,K08697 - - 0.000000000000000000000000005074 117.0
HFD3_k127_156662_15 Tetratricopeptide repeat - - - 0.00000000000000000002747 98.0
HFD3_k127_156662_16 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.0000000000000000001745 91.0
HFD3_k127_156662_17 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - 0.00000000000000007657 83.0
HFD3_k127_156662_18 YbbR-like protein - - - 0.0000000000172 77.0
HFD3_k127_156662_19 thiolester hydrolase activity - - - 0.0000000001957 73.0
HFD3_k127_156662_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015 - 1.1.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 293.0
HFD3_k127_156662_20 - - - - 0.000000003996 70.0
HFD3_k127_156662_21 Belongs to the ArsC family K00537 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.20.4.1 0.000001053 54.0
HFD3_k127_156662_22 YbbR-like protein - - - 0.000008174 59.0
HFD3_k127_156662_23 ECF sigma factor family protein - - - 0.00001271 48.0
HFD3_k127_156662_24 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0001207 47.0
HFD3_k127_156662_25 YHS domain - - - 0.0006325 50.0
HFD3_k127_156662_3 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 291.0
HFD3_k127_156662_4 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006818 284.0
HFD3_k127_156662_5 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K04068,K10026 - 1.97.1.4,4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001102 279.0
HFD3_k127_156662_6 Threonine alanine tRNA ligase second additional domain protein K01872 - 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002522 286.0
HFD3_k127_156662_7 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000000000001826 255.0
HFD3_k127_156662_8 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002558 258.0
HFD3_k127_156662_9 PFAM Class II aldolase adducin K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000003468 246.0
HFD3_k127_1568698_0 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 347.0
HFD3_k127_1568698_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K14161 - - 0.0000000000000000000000000000000000004407 156.0
HFD3_k127_1568698_2 recA bacterial DNA recombination protein - - - 0.0000000000000000000002408 106.0
HFD3_k127_1593979_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 8.045e-219 699.0
HFD3_k127_1593979_1 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 484.0
HFD3_k127_1593979_2 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 425.0
HFD3_k127_1593979_3 Protein of unknown function (DUF421) - - - 0.0000000000000000000000000000000000004845 151.0
HFD3_k127_1593979_4 Alginate export - - - 0.0000000000000000000000000000005845 128.0
HFD3_k127_1593979_5 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000000001886 119.0
HFD3_k127_1593979_6 membrane K07027,K14205 - 2.3.2.3 0.000000000000000000000007932 105.0
HFD3_k127_1596425_0 Sigma-54 factor interaction domain-containing protein K02481,K07712,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003895 277.0
HFD3_k127_1596425_1 - - - - 0.0000000000000006731 84.0
HFD3_k127_159722_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1213.0
HFD3_k127_159722_1 phosphorelay signal transduction system K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004668 528.0
HFD3_k127_159722_2 Multi-sensor signal transduction histidine kinase K07710 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 320.0
HFD3_k127_159722_3 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001853 263.0
HFD3_k127_159722_4 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000007903 163.0
HFD3_k127_159722_5 Parallel beta-helix repeats - - - 0.0000000000000000000000000000001034 133.0
HFD3_k127_159722_6 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000004843 139.0
HFD3_k127_159722_7 Periplasmic or secreted lipoprotein - - - 0.0000000000000000000009418 105.0
HFD3_k127_159722_8 CAAX protease self-immunity - - - 0.00004114 54.0
HFD3_k127_1612183_0 cellulose binding - - - 8.528e-210 655.0
HFD3_k127_1612183_1 Beta-galactosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003712 479.0
HFD3_k127_1612183_10 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.00000000000000000000000000000000002618 145.0
HFD3_k127_1612183_11 NIPSNAP family containing protein - - - 0.000000000000000000000000000008719 127.0
HFD3_k127_1612183_12 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000003684 92.0
HFD3_k127_1612183_2 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 390.0
HFD3_k127_1612183_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006695 366.0
HFD3_k127_1612183_4 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007467 326.0
HFD3_k127_1612183_5 Lactonase, 7-bladed beta-propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 299.0
HFD3_k127_1612183_6 catalyzes the formation of indole and pyruvate from tryptophan K01667 - 4.1.99.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001289 282.0
HFD3_k127_1612183_7 Methyltransferase, chemotaxis proteins K00575,K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000041 190.0
HFD3_k127_1612183_8 LysM domain - - - 0.000000000000000000000000000000000000000000000001591 192.0
HFD3_k127_1612183_9 YCII-related domain - - - 0.000000000000000000000000000000000000000002082 158.0
HFD3_k127_1621127_0 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004189 429.0
HFD3_k127_1641376_0 Rhamnogalacturonan lyase B, N-terminal K18195 - 4.2.2.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004752 529.0
HFD3_k127_1642139_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1022.0
HFD3_k127_1642139_1 Myo-inositol-1-phosphate synthase, GAPDH domain protein K01858 - 5.5.1.4 2.595e-201 634.0
HFD3_k127_1642139_10 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000527 53.0
HFD3_k127_1642139_2 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007835 248.0
HFD3_k127_1642139_3 Zinc transporter K16267 - - 0.0000000000000000000000000000000000000000000000000000000000007423 219.0
HFD3_k127_1642139_4 BON domain - - - 0.00000000000000000000000000003541 125.0
HFD3_k127_1642139_5 von Willebrand factor, type A - - - 0.00000000000000000000000002199 122.0
HFD3_k127_1642139_6 TIGRFAM TonB K03832 - - 0.0000000000000000000000001081 120.0
HFD3_k127_1642139_7 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000111 103.0
HFD3_k127_1642139_8 PFAM S23 ribosomal protein - - - 0.000000000000000008685 85.0
HFD3_k127_1642139_9 - - - - 0.000000001271 66.0
HFD3_k127_1653665_0 Xylose isomerase-like TIM barrel K03079 - 5.1.3.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000453 301.0
HFD3_k127_1653665_1 Alpha-L-fucosidase K01206 - 3.2.1.51 0.000000000000000000000000000000000000000008411 157.0
HFD3_k127_1653665_2 methylamine metabolic process K15977 - - 0.0000000000000000000000000000004021 127.0
HFD3_k127_1654723_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 430.0
HFD3_k127_1654723_1 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 372.0
HFD3_k127_1654723_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 331.0
HFD3_k127_1654723_3 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008905 324.0
HFD3_k127_1654723_4 Transposase IS116/IS110/IS902 family K07486 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002941 275.0
HFD3_k127_1654723_5 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000975 193.0
HFD3_k127_1654723_6 Protein of unknown function (DUF1634) - - - 0.00004053 57.0
HFD3_k127_1654723_7 response regulator K01768,K02584,K07183,K22010 - 4.6.1.1 0.00005778 55.0
HFD3_k127_1656296_0 radical SAM domain protein K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 390.0
HFD3_k127_1656296_1 histidine kinase HAMP region domain protein K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 317.0
HFD3_k127_1656296_2 PFAM peptidase M52 hydrogen uptake protein K03605 - - 0.000004121 55.0
HFD3_k127_1657183_0 lysine biosynthetic process via aminoadipic acid - - - 6.208e-275 867.0
HFD3_k127_1657183_1 Enoyl-(Acyl carrier protein) reductase K07124 - - 0.0000000000000000007198 88.0
HFD3_k127_1657183_2 RibD C-terminal domain - - - 0.0000000007545 60.0
HFD3_k127_166266_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 6.879e-207 660.0
HFD3_k127_1665777_0 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005024 495.0
HFD3_k127_1665777_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 436.0
HFD3_k127_1665777_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007275 419.0
HFD3_k127_1665777_3 Modulates RecA activity K03565 - - 0.0000001062 60.0
HFD3_k127_1665777_4 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000695 46.0
HFD3_k127_1667456_0 IclR helix-turn-helix domain K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005812 524.0
HFD3_k127_1667456_1 sugar isomerase K01820 - 5.3.1.14 0.00000000000000000000000000001257 121.0
HFD3_k127_1696919_0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 1.812e-226 717.0
HFD3_k127_1696919_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 576.0
HFD3_k127_1696919_2 Two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007998 365.0
HFD3_k127_1696919_3 Cell division ATP-binding protein ftsE K09811,K09812 GO:0000166,GO:0000287,GO:0000910,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0007049,GO:0008144,GO:0008150,GO:0008356,GO:0009898,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019897,GO:0019898,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0030145,GO:0030554,GO:0031234,GO:0032153,GO:0032506,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042173,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043937,GO:0043938,GO:0044085,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1902531 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003401 270.0
HFD3_k127_1696919_4 HD domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000004496 228.0
HFD3_k127_1696919_5 MOFRL family K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000003176 178.0
HFD3_k127_1696919_6 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811,K09812 GO:0000910,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006928,GO:0007049,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008356,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0016020,GO:0016021,GO:0016043,GO:0019221,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0023052,GO:0030312,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0032153,GO:0032506,GO:0034097,GO:0040007,GO:0040011,GO:0042173,GO:0042221,GO:0043207,GO:0043937,GO:0043938,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0048870,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070098,GO:0070297,GO:0070887,GO:0071310,GO:0071345,GO:0071840,GO:0071944,GO:0071976,GO:0090529,GO:1902531 - 0.000000000000000000000000000000000001892 149.0
HFD3_k127_1724269_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000002116 244.0
HFD3_k127_1724269_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000002157 227.0
HFD3_k127_1724269_2 oxidoreductase activity - - - 0.0000000000000000000000000000004881 143.0
HFD3_k127_1724269_3 oxidoreductase activity - - - 0.0000000000000001344 94.0
HFD3_k127_1762423_0 PFAM type II secretion system protein E K02283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004219 544.0
HFD3_k127_1762423_1 ATPase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006761 387.0
HFD3_k127_1762423_10 repeat-containing protein - - - 0.00000000004488 74.0
HFD3_k127_1762423_11 Putative Flp pilus-assembly TadE/G-like - - - 0.000003169 59.0
HFD3_k127_1762423_2 Belongs to the GSP D family K02280 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 315.0
HFD3_k127_1762423_3 Type II secretion system K12511 - - 0.0000000000000000000000000000000000000000000000000000000000203 217.0
HFD3_k127_1762423_4 Type II secretion system K12510 - - 0.00000000000000000000000000000000000000000000000000000007812 213.0
HFD3_k127_1762423_5 response regulator K02282 - - 0.0000000000000000000000000000000001014 150.0
HFD3_k127_1762423_6 PFAM SAF domain K02279 - - 0.00000000000000000000000000000009247 131.0
HFD3_k127_1762423_7 von Willebrand factor, type A - - - 0.0000000000000000000000000001257 134.0
HFD3_k127_1762423_8 - - - - 0.00000000000000000000000003709 121.0
HFD3_k127_1762423_9 PFAM von Willebrand factor type A - - - 0.00000000000000000000000129 121.0
HFD3_k127_1801290_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885,K09698 - 6.1.1.17,6.1.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 397.0
HFD3_k127_1801290_1 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000002288 231.0
HFD3_k127_1804640_0 Dehydratase family K01687 - 4.2.1.9 8.773e-201 642.0
HFD3_k127_1804640_1 extracellular solute-binding protein, family 7 K11688 - - 0.0000001311 58.0
HFD3_k127_1812728_0 AcrB/AcrD/AcrF family - - - 0.0 1209.0
HFD3_k127_1812728_1 Domains REC, sigma54 interaction, HTH8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003486 481.0
HFD3_k127_1812728_10 Protein of unknown function (DUF2892) - - - 0.00000000000000005824 83.0
HFD3_k127_1812728_11 Universal stress protein - - - 0.0000000000002863 79.0
HFD3_k127_1812728_12 Sigma-70 region 2 - - - 0.0000002768 61.0
HFD3_k127_1812728_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009306 328.0
HFD3_k127_1812728_3 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 306.0
HFD3_k127_1812728_4 HlyD family secretion protein - - - 0.000000000000000000000000000000000000000000000000003168 199.0
HFD3_k127_1812728_5 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000002448 162.0
HFD3_k127_1812728_6 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.000000000000000000000000000000003182 135.0
HFD3_k127_1812728_7 Tetratricopeptide repeat - - - 0.00000000000000000000000004986 115.0
HFD3_k127_1812728_8 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000001207 94.0
HFD3_k127_1812728_9 NifU-like domain - - - 0.00000000000000005387 84.0
HFD3_k127_1835989_0 PFAM Glycoside hydrolase, family 42 K12308 - 3.2.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008887 587.0
HFD3_k127_1835989_1 alpha-L-rhamnosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002403 241.0
HFD3_k127_1838191_0 Sigma-54 interaction domain K15836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006227 574.0
HFD3_k127_1838191_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 301.0
HFD3_k127_1838191_3 Uncharacterised MFS-type transporter YbfB - - - 0.00000000001937 64.0
HFD3_k127_1858889_0 WD40 repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000837 360.0
HFD3_k127_1858889_1 TIR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002487 257.0
HFD3_k127_18777_0 DNA topological change - - - 1.073e-252 805.0
HFD3_k127_18777_1 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000429 564.0
HFD3_k127_18777_2 MatE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008648 541.0
HFD3_k127_18777_3 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008845 421.0
HFD3_k127_18777_4 dioxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 406.0
HFD3_k127_18777_5 ATPases associated with a variety of cellular activities K05847 GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0031460,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0072337 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 303.0
HFD3_k127_18777_6 helix_turn_helix, cAMP Regulatory protein K21564 - - 0.00000000000000000000000000000000009236 142.0
HFD3_k127_18777_7 von Willebrand factor, type A - - - 0.0000000000000000000000000006323 124.0
HFD3_k127_18777_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000003341 83.0
HFD3_k127_1884968_0 PFAM transposase, IS4 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003585 291.0
HFD3_k127_1884968_1 Integrase core domain - - - 0.0000000000000000000000000000000000000000000000000000000000007169 214.0
HFD3_k127_1884968_2 Peptidase family S58 K01266 - 3.4.11.19 0.00000000000000000000007406 101.0
HFD3_k127_188667_0 PFAM PhoD-like phosphatase K01113 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007244 606.0
HFD3_k127_188667_1 Protein of unknown function (DUF3079) - - - 0.0000000000000002747 93.0
HFD3_k127_188667_2 - - - - 0.00000000000001568 75.0
HFD3_k127_188667_4 Methyltransferase domain - - - 0.00001084 56.0
HFD3_k127_188667_5 Protein of unknown function (DUF3617) - - - 0.00004623 51.0
HFD3_k127_1898491_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 2.061e-238 754.0
HFD3_k127_1898491_1 phosphoprotein phosphatase activity K14680 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000004326 235.0
HFD3_k127_1898491_2 ACT domain K12524 - 1.1.1.3,2.7.2.4 0.000000000000000000000000000000000000000000000136 173.0
HFD3_k127_1898491_3 chlorophyll binding - - - 0.0000000000005736 82.0
HFD3_k127_1921787_0 TIGRFAM Cell shape determining protein MreB Mrl K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006002 548.0
HFD3_k127_1921787_1 Ribonuclease E/G family K08300,K08301 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008996,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 494.0
HFD3_k127_1921787_10 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001928 273.0
HFD3_k127_1921787_11 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000944 237.0
HFD3_k127_1921787_12 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000001732 211.0
HFD3_k127_1921787_13 cyclic diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000006218 212.0
HFD3_k127_1921787_14 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000004664 189.0
HFD3_k127_1921787_15 Cytidine and deoxycytidylate deaminase zinc-binding region K01489 - 3.5.4.5 0.00000000000000000000000000000000000000005293 159.0
HFD3_k127_1921787_16 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000001298 154.0
HFD3_k127_1921787_17 SurA N-terminal domain K03770 - 5.2.1.8 0.000000000000000000000000000000000002417 152.0
HFD3_k127_1921787_18 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000017 144.0
HFD3_k127_1921787_19 NUDIX domain - - - 0.0000000000000000000000000000000582 131.0
HFD3_k127_1921787_2 PFAM Glycosyl transferase, family K00756 - 2.4.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 475.0
HFD3_k127_1921787_20 PFAM Methylated-DNA- protein -cysteine S-methyltransferase K00567 - 2.1.1.63 0.000000000000001946 83.0
HFD3_k127_1921787_21 Putative adhesin - - - 0.00000000009283 76.0
HFD3_k127_1921787_22 shape-determining protein MreD K03571 - - 0.00000005348 61.0
HFD3_k127_1921787_23 lyase activity - - - 0.000003043 61.0
HFD3_k127_1921787_24 - - - - 0.0005507 53.0
HFD3_k127_1921787_25 Putative zinc-finger - - - 0.0008529 50.0
HFD3_k127_1921787_3 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 457.0
HFD3_k127_1921787_4 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 407.0
HFD3_k127_1921787_5 Na dependent nucleoside K03317 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 416.0
HFD3_k127_1921787_6 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004214 313.0
HFD3_k127_1921787_7 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000433 307.0
HFD3_k127_1921787_8 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 307.0
HFD3_k127_1921787_9 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 301.0
HFD3_k127_1937821_0 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 301.0
HFD3_k127_1937821_1 ParB-like nuclease domain K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000126 225.0
HFD3_k127_1937821_2 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000002988 66.0
HFD3_k127_1937821_3 ATP synthase B/B' CF(0) K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00001888 56.0
HFD3_k127_1937821_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0009976 49.0
HFD3_k127_1945165_0 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 542.0
HFD3_k127_1945165_1 transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000002758 246.0
HFD3_k127_1948215_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1142.0
HFD3_k127_1948215_1 MutS domain I K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 3.317e-260 830.0
HFD3_k127_1948215_10 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000001607 202.0
HFD3_k127_1948215_11 Histidine kinase K13598 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000006999 215.0
HFD3_k127_1948215_12 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.0000000000000000000000000009318 119.0
HFD3_k127_1948215_13 PFAM peptidase M22 glycoprotease K01409,K14742 - 2.3.1.234 0.0000000000000000000000002713 116.0
HFD3_k127_1948215_14 serine threonine protein kinase - - - 0.00000000000000011 93.0
HFD3_k127_1948215_15 lipopolysaccharide transport K09774 - - 0.00000000000077 83.0
HFD3_k127_1948215_16 Protein of unknown function (DUF465) - - - 0.00000002173 59.0
HFD3_k127_1948215_17 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.00000004857 57.0
HFD3_k127_1948215_18 - - - - 0.0004295 47.0
HFD3_k127_1948215_2 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 7.05e-207 656.0
HFD3_k127_1948215_3 single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 452.0
HFD3_k127_1948215_4 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 433.0
HFD3_k127_1948215_5 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004044 353.0
HFD3_k127_1948215_6 PFAM ABC transporter K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 318.0
HFD3_k127_1948215_7 Alanine-glyoxylate amino-transferase K05825 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 320.0
HFD3_k127_1948215_8 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004411 329.0
HFD3_k127_1948215_9 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000001045 221.0
HFD3_k127_195146_0 Glycosyl hydrolase family 3 K05349 - 3.2.1.21 4.793e-249 787.0
HFD3_k127_195146_1 transmembrane transporter activity K08225 - - 0.0000000000000000000000000000000000000000000000000000000000003299 226.0
HFD3_k127_195146_2 Acid phosphatase homologues - - - 0.000000000007257 76.0
HFD3_k127_195146_3 Transmembrane secretion effector - - - 0.0000000006084 71.0
HFD3_k127_195146_4 Cupin 2, conserved barrel domain protein - - - 0.0000006143 52.0
HFD3_k127_1965179_0 Belongs to the IlvD Edd family K22396 - 4.2.1.82 1.862e-302 939.0
HFD3_k127_1965179_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 1.238e-219 689.0
HFD3_k127_1965179_2 belongs to the aldehyde dehydrogenase family K22187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 588.0
HFD3_k127_1965179_3 fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008713 533.0
HFD3_k127_1965179_4 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000001212 143.0
HFD3_k127_1976160_0 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000001123 220.0
HFD3_k127_1994663_0 TonB-dependent receptor - - - 2.002e-314 997.0
HFD3_k127_1994663_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007817 629.0
HFD3_k127_1994663_2 Pfam Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009777 508.0
HFD3_k127_1994663_3 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 453.0
HFD3_k127_1994663_4 Sulfatase-modifying factor enzyme 1 K13444 - 1.8.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 401.0
HFD3_k127_1994663_5 Domain of unknown function (DUF4976) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008769 318.0
HFD3_k127_1994663_6 Methyltransferase FkbM domain - - - 0.000000000000000000004408 104.0
HFD3_k127_1994663_7 Hsp20/alpha crystallin family - - - 0.000000000000000000005889 107.0
HFD3_k127_2010249_0 Major facilitator Superfamily K08223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 320.0
HFD3_k127_2010249_1 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002602 241.0
HFD3_k127_2033539_0 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 2.348e-289 908.0
HFD3_k127_2033539_1 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 441.0
HFD3_k127_2033539_2 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 352.0
HFD3_k127_2033539_3 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 304.0
HFD3_k127_2033539_4 Two component, sigma54 specific, transcriptional regulator, Fis family K07712 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003239 300.0
HFD3_k127_2033539_5 radical SAM domain protein - - - 0.000000000000000000000000000000000000000004641 164.0
HFD3_k127_2033539_6 Belongs to the 5'-nucleotidase family - - - 0.00000000002902 73.0
HFD3_k127_2033539_7 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.000002831 53.0
HFD3_k127_2039392_0 High confidence in function and specificity - - - 5.383e-279 876.0
HFD3_k127_2039392_1 Domain of unknown function (DUF3459) K01236 - 3.2.1.141 1.776e-240 761.0
HFD3_k127_2039392_10 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 377.0
HFD3_k127_2039392_11 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009798 380.0
HFD3_k127_2039392_12 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 371.0
HFD3_k127_2039392_13 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01431,K12251 - 3.5.1.53,3.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003853 366.0
HFD3_k127_2039392_14 Histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003675 343.0
HFD3_k127_2039392_15 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006238 312.0
HFD3_k127_2039392_16 Predicted membrane protein (DUF2231) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002142 250.0
HFD3_k127_2039392_17 Mechanosensitive ion channel K22044 - - 0.00000000000000000000000000000000000000000000006366 181.0
HFD3_k127_2039392_18 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000002294 184.0
HFD3_k127_2039392_19 - - - - 0.0000000000000000000000000000000000000000348 159.0
HFD3_k127_2039392_2 Response regulator receiver - - - 7.977e-205 648.0
HFD3_k127_2039392_20 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000002961 126.0
HFD3_k127_2039392_21 Lipocalin-like domain - - - 0.0000000000002009 81.0
HFD3_k127_2039392_22 ankyrin repeat - - - 0.00001215 56.0
HFD3_k127_2039392_3 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 587.0
HFD3_k127_2039392_4 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 523.0
HFD3_k127_2039392_5 Belongs to the DapA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 462.0
HFD3_k127_2039392_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000873 467.0
HFD3_k127_2039392_7 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 454.0
HFD3_k127_2039392_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 436.0
HFD3_k127_2039392_9 NAD dependent epimerase/dehydratase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007152 422.0
HFD3_k127_2062719_0 Trypsin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009693 374.0
HFD3_k127_2077531_0 PLD-like domain K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003723 389.0
HFD3_k127_2077531_1 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004928 355.0
HFD3_k127_2077531_2 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000002942 224.0
HFD3_k127_2077531_3 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.0000000000000000000000000000001319 131.0
HFD3_k127_2077531_4 domain protein K14194 - - 0.00000000000000000000001126 115.0
HFD3_k127_2077531_5 - - - - 0.000000000000000004218 84.0
HFD3_k127_2077531_6 Belongs to the peptidase M28 family - - - 0.0000000000000002763 92.0
HFD3_k127_2116866_0 TonB-dependent receptor - - - 1.743e-315 1011.0
HFD3_k127_2116866_1 Belongs to the glycosyl hydrolase 2 family K01190 - 3.2.1.23 3.136e-275 882.0
HFD3_k127_2116866_2 Involved in the anomeric conversion of L-rhamnose K03534 - 5.1.3.32 0.00000000000000000000000000000000000000002926 158.0
HFD3_k127_2116866_3 Alpha-L-arabinofuranosidase C-terminus K01209 - 3.2.1.55 0.00000000000000000000000002494 115.0
HFD3_k127_2116866_4 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000006323 55.0
HFD3_k127_2116866_5 Carboxypeptidase regulatory-like domain - - - 0.000001045 50.0
HFD3_k127_2118068_0 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000001072 221.0
HFD3_k127_2157706_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 1.385e-304 947.0
HFD3_k127_2157706_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 587.0
HFD3_k127_2157706_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004623 488.0
HFD3_k127_2157706_3 Osmosensitive K channel His kinase sensor K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 441.0
HFD3_k127_2157706_4 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003881 349.0
HFD3_k127_2157706_5 reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 306.0
HFD3_k127_2157706_6 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000002987 238.0
HFD3_k127_2157706_7 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.0000000000000000000000000000000000000000001083 167.0
HFD3_k127_2163719_0 Carboxypeptidase regulatory-like domain - - - 0.0 1077.0
HFD3_k127_2163719_1 cellulose binding - - - 1.888e-263 845.0
HFD3_k127_2163719_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 370.0
HFD3_k127_2163719_11 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 377.0
HFD3_k127_2163719_12 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004215 309.0
HFD3_k127_2163719_13 G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000252 274.0
HFD3_k127_2163719_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002874 277.0
HFD3_k127_2163719_15 Phosphomethylpyrimidine kinase K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000001865 264.0
HFD3_k127_2163719_16 - - - - 0.000000000000000000000000000000000000000000000000000000000000007228 227.0
HFD3_k127_2163719_17 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000005508 184.0
HFD3_k127_2163719_18 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000004157 175.0
HFD3_k127_2163719_19 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000001023 157.0
HFD3_k127_2163719_2 Carboxypeptidase regulatory-like domain - - - 1.222e-240 792.0
HFD3_k127_2163719_20 O-Antigen ligase K18814 - - 0.000000000000000000000000000000000000000001335 179.0
HFD3_k127_2163719_21 Glycosyl transferase, family 9 K02843,K02849 - - 0.00000000000000000000000000000000000000001321 167.0
HFD3_k127_2163719_22 NADH dehydrogenase (ubiquinone) flavoprotein 2 K03943 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007005,GO:0007275,GO:0007399,GO:0007507,GO:0008137,GO:0008150,GO:0008152,GO:0009055,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009888,GO:0009987,GO:0010257,GO:0014706,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0019866,GO:0022607,GO:0022900,GO:0022904,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0032981,GO:0032991,GO:0033108,GO:0034622,GO:0034641,GO:0042773,GO:0042775,GO:0043209,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045271,GO:0045333,GO:0046034,GO:0046483,GO:0048513,GO:0048731,GO:0048738,GO:0048856,GO:0050136,GO:0055086,GO:0055114,GO:0060537,GO:0065003,GO:0070469,GO:0071704,GO:0071840,GO:0072359,GO:0072521,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000001168 161.0
HFD3_k127_2163719_23 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000006706 144.0
HFD3_k127_2163719_24 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000000000000001346 127.0
HFD3_k127_2163719_25 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000000000001885 120.0
HFD3_k127_2163719_26 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000000000004543 114.0
HFD3_k127_2163719_27 Trm112p-like protein K00912,K09791 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.7.1.130 0.0000000000000002916 85.0
HFD3_k127_2163719_29 - - - - 0.00000002623 66.0
HFD3_k127_2163719_3 NADH-Ubiquinone oxidoreductase (complex I), chain 5 K00341 - 1.6.5.3 1.178e-196 635.0
HFD3_k127_2163719_4 proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 578.0
HFD3_k127_2163719_5 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 518.0
HFD3_k127_2163719_6 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006544 487.0
HFD3_k127_2163719_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 493.0
HFD3_k127_2163719_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 462.0
HFD3_k127_2163719_9 Proton-conducting membrane transporter K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004059 379.0
HFD3_k127_218902_0 alpha-L-fucosidase K15923 - 3.2.1.51 1.552e-252 802.0
HFD3_k127_218902_1 carboxylic acid catabolic process K18334 - 4.2.1.68 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003633 617.0
HFD3_k127_218902_2 ABC transporter K10441 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 550.0
HFD3_k127_218902_3 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003585 411.0
HFD3_k127_218902_4 Periplasmic binding proteins and sugar binding domain of LacI family K10439,K10552 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 347.0
HFD3_k127_218902_5 3-beta hydroxysteroid dehydrogenase/isomerase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007146 320.0
HFD3_k127_218902_6 Belongs to the binding-protein-dependent transport system permease family K10440,K17203 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003593 322.0
HFD3_k127_218902_7 PFAM Amidohydrolase 2 K07046 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 319.0
HFD3_k127_218902_8 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000007731 255.0
HFD3_k127_218902_9 L-rhamnose mutarotase K03534 - 5.1.3.32 0.00000000000000000000009612 110.0
HFD3_k127_220799_0 Sortilin, neurotensin receptor 3, - - - 0.0 1125.0
HFD3_k127_220799_1 COG0457 FOG TPR repeat - - - 6.839e-241 760.0
HFD3_k127_220799_2 choline dehydrogenase activity - - - 1.996e-221 705.0
HFD3_k127_220799_3 FAD dependent oxidoreductase K00301 - 1.5.3.1 0.000000000000000000000000000000000000000000003428 168.0
HFD3_k127_220799_4 acetyltransferase K03789 - 2.3.1.128 0.00000000000000000001774 102.0
HFD3_k127_220799_6 SMART phosphoesterase PHP domain protein - - - 0.000000004314 67.0
HFD3_k127_2247041_0 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000534 435.0
HFD3_k127_2247041_1 glycerophosphoryl diester phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 300.0
HFD3_k127_2247041_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000258 138.0
HFD3_k127_2291469_0 Sulfite reductase K00366,K00381,K00392 - 1.7.7.1,1.8.1.2,1.8.7.1 1.639e-215 686.0
HFD3_k127_2291469_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.103e-196 628.0
HFD3_k127_2291469_2 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000000000000000002741 164.0
HFD3_k127_2291469_3 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000007852 57.0
HFD3_k127_229391_0 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009409 553.0
HFD3_k127_229391_1 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 507.0
HFD3_k127_229391_10 - - - - 0.0000000000000000000000001346 111.0
HFD3_k127_229391_11 acetyltransferase - - - 0.000000000000000000007711 100.0
HFD3_k127_229391_12 Protein of unknown function (DUF3311) - - - 0.000000000003488 68.0
HFD3_k127_229391_2 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009493 422.0
HFD3_k127_229391_3 Iron-containing alcohol dehydrogenase K00001,K13954 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006108 376.0
HFD3_k127_229391_4 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006 360.0
HFD3_k127_229391_5 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008327 325.0
HFD3_k127_229391_6 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009871 317.0
HFD3_k127_229391_7 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001343 287.0
HFD3_k127_229391_8 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000101 282.0
HFD3_k127_229391_9 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000007697 192.0
HFD3_k127_2307838_0 PQQ-like domain K00117 - 1.1.5.2 0.0 1155.0
HFD3_k127_2307838_1 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 8.142e-215 690.0
HFD3_k127_2307838_2 efflux transmembrane transporter activity - - - 7.16e-197 642.0
HFD3_k127_2307838_3 hydrolase family 20, catalytic K12373 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003871 543.0
HFD3_k127_2307838_4 Spermine/spermidine synthase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006656 499.0
HFD3_k127_2307838_5 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 409.0
HFD3_k127_2307838_6 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000006526 196.0
HFD3_k127_2307838_7 redox protein, regulator of disulfide bond formation - - - 0.0000000000000000000000000000000000000000004288 164.0
HFD3_k127_2307838_8 HupE / UreJ protein - - - 0.000000000000000001538 99.0
HFD3_k127_2352090_0 synthetase (ADP forming), alpha K01905,K09181,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 490.0
HFD3_k127_2352090_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 343.0
HFD3_k127_2352090_2 ABC transporter K15738 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010528,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031323,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0070894,GO:0071944,GO:0080090,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000001204 251.0
HFD3_k127_2352090_3 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000004778 201.0
HFD3_k127_2352090_4 - - - - 0.00000000000000000000001301 111.0
HFD3_k127_2389541_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 517.0
HFD3_k127_2389541_1 symporter activity K03307,K11928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 407.0
HFD3_k127_2389541_2 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006543 368.0
HFD3_k127_2389541_3 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005676 346.0
HFD3_k127_2389541_4 DNA ligase K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000001478 214.0
HFD3_k127_2389541_5 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.000000000000000000000000001787 115.0
HFD3_k127_2389541_6 Stress-induced bacterial acidophilic repeat motif - - - 0.00000000000001609 79.0
HFD3_k127_2397092_0 Periplasmic component of the Tol biopolymer transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000736 614.0
HFD3_k127_2397092_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342,K03703,K04096 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 2.7.7.7 0.000000000000000000000000000000000000000000000000000006057 217.0
HFD3_k127_2397092_2 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000009625 191.0
HFD3_k127_2397092_3 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.000000000000000000001429 107.0
HFD3_k127_2397092_4 Belongs to the glycosyl hydrolase 26 family - - - 0.000000000000000001769 95.0
HFD3_k127_2401217_0 Zinc carboxypeptidase - - - 2.869e-284 890.0
HFD3_k127_2401217_1 cell redox homeostasis K00384,K12057,K12267,K21636 - 1.1.98.6,1.8.1.9,1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007052 355.0
HFD3_k127_2411767_0 Protein kinase domain K12132 - 2.7.11.1 3.374e-204 646.0
HFD3_k127_2411767_1 Peptidase family S51 - - - 0.00000000000000000004491 96.0
HFD3_k127_2465741_0 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006826 482.0
HFD3_k127_2465741_1 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006564 427.0
HFD3_k127_2465741_10 COG2755 Lysophospholipase L1 and related esterases K10804 GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564 3.1.1.5 0.00000000000000000000000000000000000000000000000001269 188.0
HFD3_k127_2465741_11 - - - - 0.000000000000000000000000001904 119.0
HFD3_k127_2465741_13 Protein of unknown function (DUF763) K09003 - - 0.00000000005759 69.0
HFD3_k127_2465741_14 Protein of unknown function (DUF763) K09003 - - 0.00003111 55.0
HFD3_k127_2465741_2 Cytochrome c3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005826 389.0
HFD3_k127_2465741_3 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 361.0
HFD3_k127_2465741_4 eRF1 domain 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006455 318.0
HFD3_k127_2465741_5 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 302.0
HFD3_k127_2465741_6 FRG - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005523 308.0
HFD3_k127_2465741_7 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004683 273.0
HFD3_k127_2465741_8 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006876 262.0
HFD3_k127_2465741_9 Rubrerythrin K22336 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000003974 204.0
HFD3_k127_2482479_0 N-acetyldiaminopimelate deacetylase activity K12941 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007251 585.0
HFD3_k127_2482479_1 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004967 452.0
HFD3_k127_2482479_2 L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000000005379 201.0
HFD3_k127_2482479_3 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.0000000000000000000000000000000000000000000000000000007078 198.0
HFD3_k127_248299_0 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005365 336.0
HFD3_k127_248299_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009805 285.0
HFD3_k127_248299_2 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005935 276.0
HFD3_k127_248299_3 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000001967 207.0
HFD3_k127_248299_4 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000000000884 160.0
HFD3_k127_2483356_0 von Willebrand factor, type A K12511 - - 0.000000000000000000000000009696 123.0
HFD3_k127_2483356_1 Gram-negative bacterial TonB protein C-terminal - - - 0.0000000000000000000000002135 116.0
HFD3_k127_2494377_0 Pyridoxal-dependent decarboxylase conserved domain K01593,K01634 - 4.1.1.105,4.1.1.28,4.1.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 582.0
HFD3_k127_2494377_1 Putative phosphatase (DUF442) - - - 0.00000000000003212 79.0
HFD3_k127_2494377_2 BON domain - - - 0.0000000000001205 80.0
HFD3_k127_2495773_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007714 403.0
HFD3_k127_2495773_1 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 406.0
HFD3_k127_2495773_2 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.0000000000000000000000000000000000000000000000000000000000000001277 235.0
HFD3_k127_2495773_3 serine-type endopeptidase activity K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000003475 193.0
HFD3_k127_2495773_4 Cleaves the N-terminal amino acid of tripeptides K01258 - 3.4.11.4 0.000000000000000000000000000000000000000000000002385 179.0
HFD3_k127_2495773_5 PFAM regulatory protein LuxR - - - 0.0000000000000001035 85.0
HFD3_k127_2495773_6 PFAM Uncharacterised protein family (UPF0153) K18475 - - 0.0002192 53.0
HFD3_k127_2498886_0 Dynamin family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000469 515.0
HFD3_k127_2498886_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 421.0
HFD3_k127_2498886_2 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000000000000017 202.0
HFD3_k127_2498886_3 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000004995 181.0
HFD3_k127_2498886_4 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000004548 138.0
HFD3_k127_2498886_5 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000001282 90.0
HFD3_k127_2498886_6 fatty acid desaturase - - - 0.0000000000000001031 91.0
HFD3_k127_2498886_7 ATP hydrolysis coupled proton transport K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000006471 73.0
HFD3_k127_2498886_8 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.000122 50.0
HFD3_k127_2502530_0 ABC transporter C-terminal domain K06158 - - 1.238e-201 648.0
HFD3_k127_2502530_1 PFAM ATP-binding region, ATPase domain protein K02668,K07708,K07709 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000002288 230.0
HFD3_k127_2502530_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000001715 203.0
HFD3_k127_2502530_3 response regulator K07713 - - 0.000000000000000000000000000000000000000000003853 169.0
HFD3_k127_2502530_4 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.00000000000000000001597 100.0
HFD3_k127_2502530_5 Excisionase - - - 0.0000000007819 62.0
HFD3_k127_2505136_0 Periplasmic or secreted lipoprotein - - - 0.00000000000003436 81.0
HFD3_k127_2505136_1 Peptidase family M48 - - - 0.0000000008599 68.0
HFD3_k127_2505136_2 peptidyl-tyrosine sulfation - - - 0.00002139 53.0
HFD3_k127_2506474_0 3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase) K01083 - 3.1.3.8 0.000000000000000000000000000000000000000000000000000000000000000008573 233.0
HFD3_k127_2506474_1 Phospholipid methyltransferase - - - 0.000000000000000000000000000000000000000000000003118 179.0
HFD3_k127_2506474_2 - - - - 0.00000000000000000000000000000000000002337 157.0
HFD3_k127_2506474_3 GyrI-like small molecule binding domain - - - 0.00000000000000000000000000000000003926 145.0
HFD3_k127_2506474_4 DinB family - - - 0.00000000000000000000000000002317 130.0
HFD3_k127_2506474_5 Protein of unknown function (DUF1569) - - - 0.0000000000000000000000001421 118.0
HFD3_k127_2506474_6 Protein of unknown function, DUF488 - - - 0.000000000000002508 77.0
HFD3_k127_2506474_7 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000001275 75.0
HFD3_k127_2506474_8 - - - - 0.0001115 53.0
HFD3_k127_2511009_0 Bacterial dnaA protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 348.0
HFD3_k127_2511009_1 PFAM Integrase catalytic - - - 0.000000000000000000000000000000000000000000000000000000871 199.0
HFD3_k127_2516211_0 L-lactate dehydrogenase K00101,K16422 - 1.1.2.3,1.1.3.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008099 503.0
HFD3_k127_2516211_1 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 436.0
HFD3_k127_2516211_2 Transcriptional regulatory protein, C terminal K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 304.0
HFD3_k127_2516211_3 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002735 296.0
HFD3_k127_2516211_4 COG0642 Signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000003276 226.0
HFD3_k127_2516211_5 ECF sigma factor K03088 - - 0.0000000000000000000000000000000004359 139.0
HFD3_k127_2516211_6 - - - - 0.00002655 53.0
HFD3_k127_2532389_0 CoA-transferase family III K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 442.0
HFD3_k127_2532389_1 Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 329.0
HFD3_k127_2532389_2 PFAM Homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000001357 222.0
HFD3_k127_2532389_3 Sulfatase-modifying factor enzyme 1 - GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005509,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016667,GO:0016670,GO:0018158,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0120147,GO:1901564,GO:1903135 - 0.0000000000000000000000000000000000000000000000003157 188.0
HFD3_k127_2532389_4 ZIP Zinc transporter K07238 - - 0.00000000000000000000000000000000000000000000003186 176.0
HFD3_k127_2532389_5 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000127 165.0
HFD3_k127_2532389_7 Protein of unknown function (DUF541) K09807 - - 0.0000000000000000000002554 108.0
HFD3_k127_2532389_8 Glutaredoxin - - - 0.000006658 50.0
HFD3_k127_2532389_9 COG2133 Glucose sorbosone dehydrogenases - - - 0.000007137 53.0
HFD3_k127_254460_0 Carbamoyl-phosphate synthetase large chain domain protein K01955 - 6.3.5.5 0.0 1339.0
HFD3_k127_254460_1 PFAM LmbE family protein K22136 - - 1.929e-198 654.0
HFD3_k127_254460_2 TIGRFAM carbamoyl-phosphate synthase, small subunit K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 435.0
HFD3_k127_254460_3 PFAM Glycosyl transferase, group 1 K00754 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007535 421.0
HFD3_k127_254460_4 Bacillithiol biosynthesis BshC K22136 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001254 293.0
HFD3_k127_254460_5 deacetylase K01463 - - 0.0000000000000000000000000000000000000000000000000000000000003799 219.0
HFD3_k127_254460_6 PFAM LmbE family protein K22136 - - 0.000000000000000000000000000000002632 129.0
HFD3_k127_254460_7 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000001405 94.0
HFD3_k127_254460_8 PFAM PEGA domain - - - 0.000000000001732 81.0
HFD3_k127_2544840_0 PFAM type II secretion system protein E K02283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004642 556.0
HFD3_k127_2544840_1 ATPase with chaperone activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 407.0
HFD3_k127_2544840_10 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000008281 93.0
HFD3_k127_2544840_2 type II secretion system K12511 - - 0.000000000000000000000000000000000000000000000000000000000002837 220.0
HFD3_k127_2544840_3 type II secretion system protein K12510 - - 0.000000000000000000000000000000000000000000000000000001315 214.0
HFD3_k127_2544840_4 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000001393 168.0
HFD3_k127_2544840_5 Response regulator, receiver K02282 - - 0.000000000000000000000000000000000000000000003115 179.0
HFD3_k127_2544840_6 PFAM ATP-binding region, ATPase domain protein - - - 0.00000000000000000000000000000000000003854 163.0
HFD3_k127_2544840_7 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000000000000006161 112.0
HFD3_k127_2544840_8 Smr domain - - - 0.000000000000000000001133 104.0
HFD3_k127_2544840_9 regulation of translation K03530 - - 0.000000000000000000162 93.0
HFD3_k127_2545004_0 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 430.0
HFD3_k127_2545004_1 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 347.0
HFD3_k127_2545004_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009697 331.0
HFD3_k127_2545004_3 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009969 287.0
HFD3_k127_2545004_4 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000000000000004326 154.0
HFD3_k127_2545004_5 PFAM Glycosyl transferase family 2 - - - 0.00000000000001189 77.0
HFD3_k127_2545004_6 Cell division protein FtsL - - - 0.0001846 49.0
HFD3_k127_2567427_0 PFAM peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006589 554.0
HFD3_k127_2567427_1 Zinc carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000004254 199.0
HFD3_k127_2580153_0 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 2.763e-234 734.0
HFD3_k127_2580153_1 PfkB domain protein K00874 - 2.7.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 587.0
HFD3_k127_2580153_2 lactate racemase activity K22373 - 5.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005535 468.0
HFD3_k127_2580153_3 Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate K03473 - 1.1.1.290 0.000000000000000000000000000000000000000000000000000000000000000001044 239.0
HFD3_k127_2580153_4 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000003034 111.0
HFD3_k127_2580153_5 Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate K03473 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0033711,GO:0034641,GO:0036001,GO:0036094,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.290 0.000000000612 63.0
HFD3_k127_2582056_0 protocatechuate 3,4-dioxygenase activity - - - 1.542e-234 767.0
HFD3_k127_2582056_1 Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005547 450.0
HFD3_k127_2582056_2 Membrane dipeptidase (Peptidase family M19) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007672 364.0
HFD3_k127_2582056_3 Methane oxygenase PmoA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 328.0
HFD3_k127_2582056_4 purine nucleotide biosynthetic process K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002225 262.0
HFD3_k127_2582056_5 DoxX K16937 - 1.8.5.2 0.000000000000000000000000000105 121.0
HFD3_k127_2582218_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 5.282e-217 701.0
HFD3_k127_2582218_1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 441.0
HFD3_k127_2582218_2 Fatty acid desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 419.0
HFD3_k127_2582218_3 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 334.0
HFD3_k127_2582218_4 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 329.0
HFD3_k127_2582218_5 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004733 336.0
HFD3_k127_2582218_6 Probable RNA and SrmB- binding site of polymerase A K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000001146 279.0
HFD3_k127_2601480_0 aconitate hydratase K01681 - 4.2.1.3 0.0 1141.0
HFD3_k127_2601480_1 Prolyl oligopeptidase family - - - 1.105e-232 741.0
HFD3_k127_2601480_2 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 530.0
HFD3_k127_2601480_3 transcriptional regulator PadR family - - - 0.000000000000000000000004048 111.0
HFD3_k127_2601480_4 - - - - 0.000000000000000009281 91.0
HFD3_k127_2601480_5 protein import - - - 0.00000000006944 73.0
HFD3_k127_2608885_0 FtsX-like permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006363 587.0
HFD3_k127_2608885_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 428.0
HFD3_k127_2608885_2 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009211 363.0
HFD3_k127_2608885_3 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004042 267.0
HFD3_k127_2608885_4 Participates in the control of copper homeostasis K06201 GO:0006873,GO:0006875,GO:0006878,GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0019725,GO:0030003,GO:0042221,GO:0042592,GO:0046688,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0055065,GO:0055070,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0098771 - 0.00000000000000000000000000000000000000003545 160.0
HFD3_k127_2608885_5 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000001142 78.0
HFD3_k127_2611735_0 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 337.0
HFD3_k127_2611735_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005472 327.0
HFD3_k127_2611735_2 PFAM DAHP synthetase I KDSA K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006555 317.0
HFD3_k127_2611735_3 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 - 3.1.3.45 0.00000000000000000000000000000000000000001314 173.0
HFD3_k127_2611768_0 Succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1009.0
HFD3_k127_2611768_1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 8.26e-265 829.0
HFD3_k127_2611768_10 4Fe-4S ferredoxin iron-sulfur binding domain protein K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 365.0
HFD3_k127_2611768_11 Cytidylyltransferase K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002234 273.0
HFD3_k127_2611768_12 - K00241 - - 0.000000000000000000000000000000000000000388 157.0
HFD3_k127_2611768_2 Isocitrate/isopropylmalate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007747 583.0
HFD3_k127_2611768_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005274 507.0
HFD3_k127_2611768_4 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 487.0
HFD3_k127_2611768_5 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003669 466.0
HFD3_k127_2611768_6 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006399 434.0
HFD3_k127_2611768_7 Serine hydrolase (FSH1) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004545 398.0
HFD3_k127_2611768_8 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 408.0
HFD3_k127_2611768_9 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 380.0
HFD3_k127_2619585_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004866 580.0
HFD3_k127_2619585_1 HELICc2 K03722 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005237 578.0
HFD3_k127_2619585_2 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 363.0
HFD3_k127_2619585_3 Site-specific DNA-methyltransferase (adenine-specific) K06223 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000008398 215.0
HFD3_k127_2619585_4 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000009493 199.0
HFD3_k127_2626139_0 PFAM oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007808 437.0
HFD3_k127_2626139_1 PFAM Pyruvate flavodoxin ferredoxin oxidoreductase K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005083 417.0
HFD3_k127_2626139_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 394.0
HFD3_k127_2626139_3 glutamate synthase (NADPH) K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004219 338.0
HFD3_k127_2626139_4 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K00187 - 1.2.7.1,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 334.0
HFD3_k127_2626139_5 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000222 223.0
HFD3_k127_2626139_6 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000001409 196.0
HFD3_k127_2626139_7 - - - - 0.000000003471 62.0
HFD3_k127_2633295_0 radical SAM domain protein - - - 4.718e-214 686.0
HFD3_k127_2633295_1 Bacterial protein of unknown function (DUF853) K06915 - - 2.223e-198 634.0
HFD3_k127_2633295_2 imidazolonepropionase activity K00466 - 1.13.12.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005173 579.0
HFD3_k127_2633295_3 Probably functions as a manganese efflux pump - - - 0.00000000000000000000000000000000000008712 162.0
HFD3_k127_2633295_4 - - - - 0.00000000000000000000000000000005643 126.0
HFD3_k127_2633295_5 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000004002 130.0
HFD3_k127_263511_0 Probably functions as a manganese efflux pump - - - 0.00000000000000000000000000000000000000000003679 183.0
HFD3_k127_263511_1 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000003863 139.0
HFD3_k127_263511_2 methyltransferase - - - 0.00000000000000000000000001167 119.0
HFD3_k127_263511_3 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000006728 58.0
HFD3_k127_2646512_0 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004934 458.0
HFD3_k127_2646512_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 301.0
HFD3_k127_2646512_10 peptidyl-tyrosine sulfation - - - 0.0000000000006144 80.0
HFD3_k127_2646512_11 protein transport across the cell outer membrane K02246,K08084 - - 0.0001814 51.0
HFD3_k127_2646512_12 pilus assembly protein PilW - - - 0.0006369 52.0
HFD3_k127_2646512_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 292.0
HFD3_k127_2646512_3 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000003964 222.0
HFD3_k127_2646512_4 - - - - 0.0000000000000000000000000000000000000000000000000000007242 201.0
HFD3_k127_2646512_5 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.000000000000000000000000000000000000000000000000000001256 198.0
HFD3_k127_2646512_6 Histidine kinase K02668,K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000001051 206.0
HFD3_k127_2646512_7 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000005652 162.0
HFD3_k127_2646512_8 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.00000000000000000000000000000005506 147.0
HFD3_k127_2646512_9 Thioredoxin - - - 0.000000000000000004391 90.0
HFD3_k127_2695120_0 Cytochrome C oxidase subunit II, periplasmic domain K00376 - 1.7.2.4 0.0 1015.0
HFD3_k127_2695120_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 3.324e-245 767.0
HFD3_k127_2695120_2 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 9.834e-228 713.0
HFD3_k127_2695120_3 Cytochrome c - - - 1.949e-195 617.0
HFD3_k127_2695120_4 Periplasmic copper-binding protein (NosD) K07218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 565.0
HFD3_k127_2695120_5 ABC transporter K01990,K19340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007526 361.0
HFD3_k127_2695120_6 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001718 279.0
HFD3_k127_2695120_7 lipoprotein involved in nitrous oxide reduction - - - 0.000000000000000000000000000000000000000000000000000000000000000000006288 261.0
HFD3_k127_2695120_8 ABC-2 family transporter protein K19341 - - 0.0000000000000000000000000000000000000000000000000000001788 210.0
HFD3_k127_2695120_9 lipoprotein involved in nitrous oxide reduction K19342 - - 0.00000000000000000000000002976 114.0
HFD3_k127_27021_0 HELICc2 K03722 - 3.6.4.12 9.675e-222 706.0
HFD3_k127_27021_1 Aminotransferase class I and II K10206 - 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000001264 256.0
HFD3_k127_27021_2 Endoribonuclease L-PSP - - - 0.0000000000000000002526 94.0
HFD3_k127_2702608_0 ATP-dependent helicase K03579 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 452.0
HFD3_k127_2702608_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07025 - - 0.000000000000000000000000000001666 136.0
HFD3_k127_2702608_2 protein-glutamate O-methyltransferase activity - - - 0.00003577 55.0
HFD3_k127_270971_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016020,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0040007,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 8.34e-264 822.0
HFD3_k127_270971_1 Belongs to the ClpA ClpB family K03695,K03696 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005193 456.0
HFD3_k127_270971_10 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000002917 119.0
HFD3_k127_270971_11 Chlorophyll synthase, ChlG K04040 - 2.5.1.133,2.5.1.62 0.00000000000000000004882 106.0
HFD3_k127_270971_12 Phosphoserine phosphatase - - - 0.00000000000001499 87.0
HFD3_k127_270971_2 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006687 401.0
HFD3_k127_270971_3 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related K01295 - 3.4.17.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009168 328.0
HFD3_k127_270971_4 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003875 310.0
HFD3_k127_270971_5 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002207 283.0
HFD3_k127_270971_6 PFAM NAD-dependent epimerase dehydratase K15856 - 1.1.1.281 0.000000000000000000000000000000000000000000000000000000000000000008562 239.0
HFD3_k127_270971_7 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744,K09774,K22110 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0009279,GO:0015267,GO:0015288,GO:0015749,GO:0015750,GO:0015751,GO:0015757,GO:0016020,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030312,GO:0030313,GO:0031975,GO:0034219,GO:0044462,GO:0044464,GO:0046323,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:1904659 - 0.00000000000000000000000000000000000000000000000000009334 211.0
HFD3_k127_270971_8 response to abiotic stimulus - - - 0.000000000000000000000000000000002798 134.0
HFD3_k127_270971_9 PFAM Integral membrane protein DUF92 - GO:0005575,GO:0016020 - 0.000000000000000000000000000002579 138.0
HFD3_k127_2737954_0 Tricorn protease homolog K08676 - - 0.0 1534.0
HFD3_k127_2737954_1 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005421 634.0
HFD3_k127_2737954_10 oxidoreductase activity - - - 0.000000000000000000000006021 118.0
HFD3_k127_2737954_11 Uncharacterized protein conserved in bacteria (DUF2255) - - - 0.0000000000000000000001072 102.0
HFD3_k127_2737954_12 Carboxypeptidase regulatory-like domain - - - 0.0000000003566 73.0
HFD3_k127_2737954_13 Periplasmic protein TonB links inner and outer membranes K03832 - - 0.000002835 59.0
HFD3_k127_2737954_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 589.0
HFD3_k127_2737954_3 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006644 599.0
HFD3_k127_2737954_4 PFAM nucleoside H symporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004329 473.0
HFD3_k127_2737954_5 Beta-L-arabinofuranosidase, GH127 K09955 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 454.0
HFD3_k127_2737954_6 ABC-type antimicrobial peptide transport system, permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 438.0
HFD3_k127_2737954_7 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000000000000000000007232 190.0
HFD3_k127_2737954_8 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.0000000000000000000000000000000000000003256 160.0
HFD3_k127_2737954_9 domain protein - - - 0.00000000000000000000000000001364 136.0
HFD3_k127_2739034_0 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 5.605e-234 737.0
HFD3_k127_2739034_1 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 505.0
HFD3_k127_2739034_10 metallophosphoesterase K07096 - - 0.0000000000000000000000000000002223 133.0
HFD3_k127_2739034_11 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000004038 126.0
HFD3_k127_2739034_12 4Fe-4S dicluster domain K05524 - - 0.000000000000000000000000000601 117.0
HFD3_k127_2739034_13 molybdate ion transport K02019 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0042802,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000008382 102.0
HFD3_k127_2739034_14 Patatin-like phospholipase K07001 - - 0.00000000000006544 83.0
HFD3_k127_2739034_16 - - - - 0.00003223 51.0
HFD3_k127_2739034_2 Amidase K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005393 466.0
HFD3_k127_2739034_3 Peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005132 394.0
HFD3_k127_2739034_4 guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000001668 237.0
HFD3_k127_2739034_5 Patatin-like phospholipase K02282,K07001 - - 0.000000000000000000000000000000000000000000000000000002218 218.0
HFD3_k127_2739034_6 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000002352 203.0
HFD3_k127_2739034_7 ErfK ybiS ycfS ynhG family protein - - - 0.0000000000000000000000000000000000000000000001154 188.0
HFD3_k127_2739034_8 methyltransferase activity - - - 0.000000000000000000000000000000000000009484 151.0
HFD3_k127_2739034_9 Domain of unknown function (DUF4440) - - - 0.00000000000000000000000000000001423 134.0
HFD3_k127_27633_0 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 418.0
HFD3_k127_27633_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004324 419.0
HFD3_k127_27633_2 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 354.0
HFD3_k127_27633_3 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 349.0
HFD3_k127_27633_4 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 340.0
HFD3_k127_27633_5 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 314.0
HFD3_k127_27633_6 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001004 295.0
HFD3_k127_2775571_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 496.0
HFD3_k127_2775571_1 Cys/Met metabolism PLP-dependent enzyme K01758 - 4.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 339.0
HFD3_k127_2775571_2 Stage II sporulation protein E K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000005044 231.0
HFD3_k127_2775571_3 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000000000000000007595 203.0
HFD3_k127_2775571_4 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000002815 99.0
HFD3_k127_2775571_5 AAA ATPase domain - - - 0.0000000001485 73.0
HFD3_k127_2809377_0 Phosphoadenosine phosphosulfate reductase family K00957 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 471.0
HFD3_k127_2809377_1 LOR/SDH bifunctional enzyme conserved region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006154 452.0
HFD3_k127_2809377_2 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00956 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007832 441.0
HFD3_k127_2809377_3 response to heat K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008174 308.0
HFD3_k127_2809377_4 Belongs to the PAPS reductase family. CysH subfamily K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000001465 270.0
HFD3_k127_2809377_5 Glycosyl hydrolase 36 superfamily, catalytic domain K00702,K13688 - 2.4.1.20 0.00000000000000000000000000000000000000000000000000001188 191.0
HFD3_k127_2809377_6 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000005493 134.0
HFD3_k127_2809377_7 PFAM Dockerin type - - - 0.00000000000000000000000001745 114.0
HFD3_k127_2821814_0 Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000685 527.0
HFD3_k127_2821814_1 Belongs to the RtcB family K14415 - 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006279 511.0
HFD3_k127_2821814_2 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 463.0
HFD3_k127_2821814_3 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 411.0
HFD3_k127_2821814_4 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000008625 208.0
HFD3_k127_2821814_5 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000000000000000004795 182.0
HFD3_k127_2821814_6 - - - - 0.00000000000000000000000000000000000000000000000000979 205.0
HFD3_k127_2821814_7 Peptidase M56 - - - 0.000000000000000000000000000000000000000002981 178.0
HFD3_k127_2821814_8 Penicillinase repressor - - - 0.000000000000000000000000002958 116.0
HFD3_k127_2821814_9 Cyclic nucleotide-monophosphate binding domain - - - 0.000000005845 66.0
HFD3_k127_285605_0 Peptidase family M1 domain K01256 - 3.4.11.2 6.034e-237 760.0
HFD3_k127_285605_1 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 396.0
HFD3_k127_285605_10 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000006703 210.0
HFD3_k127_285605_11 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000002788 196.0
HFD3_k127_285605_12 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000001629 175.0
HFD3_k127_285605_13 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000001781 166.0
HFD3_k127_285605_14 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000002892 158.0
HFD3_k127_285605_15 Forkhead associated domain - - - 0.000000000000000000000000000000103 138.0
HFD3_k127_285605_16 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000003922 128.0
HFD3_k127_285605_17 tRNA (guanine(37)-N(1))-methyltransferase activity - - - 0.00000000000000000003 107.0
HFD3_k127_285605_18 Surface antigen - - - 0.0000000000000000007594 100.0
HFD3_k127_285605_19 Polysaccharide biosynthesis/export protein - - - 0.00000000000000715 89.0
HFD3_k127_285605_2 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 359.0
HFD3_k127_285605_20 Methyltransferase domain - - - 0.0000000000001049 85.0
HFD3_k127_285605_21 Pfam:DUF2029 - - - 0.000000000001596 79.0
HFD3_k127_285605_22 polysaccharide biosynthetic process - - - 0.0000000005224 72.0
HFD3_k127_285605_3 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 353.0
HFD3_k127_285605_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 314.0
HFD3_k127_285605_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 336.0
HFD3_k127_285605_6 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 314.0
HFD3_k127_285605_7 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002749 261.0
HFD3_k127_285605_8 PFAM Asparaginase K01424 - 3.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000001446 231.0
HFD3_k127_285605_9 - - - - 0.000000000000000000000000000000000000000000000000000000000001026 229.0
HFD3_k127_2921278_0 Amino acid permease K03294,K19540 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006040,GO:0006082,GO:0006520,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008152,GO:0008509,GO:0008514,GO:0009056,GO:0009063,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0016054,GO:0019752,GO:0022804,GO:0022857,GO:0030389,GO:0030392,GO:0030393,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0046348,GO:0046395,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098656,GO:1901135,GO:1901136,GO:1901281,GO:1901564,GO:1901565,GO:1901575,GO:1902475,GO:1903825,GO:1905039 - 1.163e-216 679.0
HFD3_k127_2921278_1 carboxylic acid catabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 400.0
HFD3_k127_2921439_0 Cytochrome b/b6/petB K00412,K03888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003218 269.0
HFD3_k127_2921439_1 Rieske [2Fe-2S] domain K03886 - - 0.00000000000000000000663 98.0
HFD3_k127_2921439_2 HEAT repeats - - - 0.0000000000002002 82.0
HFD3_k127_2947145_0 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 471.0
HFD3_k127_2947145_1 phosphorelay signal transduction system K02481,K07713,K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 415.0
HFD3_k127_2947145_2 Phosphohydrolase-associated domain K01129 - 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005662 393.0
HFD3_k127_2947145_3 cytochrome oxidase assembly K02259 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 298.0
HFD3_k127_2947145_4 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000001346 75.0
HFD3_k127_2947145_5 - - - - 0.0003933 50.0
HFD3_k127_2955019_0 Glutamine amidotransferases class-II K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 608.0
HFD3_k127_2955019_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 484.0
HFD3_k127_2955019_2 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009906 474.0
HFD3_k127_2955019_3 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000773 407.0
HFD3_k127_2955019_4 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000008353 251.0
HFD3_k127_2955019_5 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000001634 148.0
HFD3_k127_2955019_6 Isoprenylcysteine carboxyl methyltransferase - - - 0.000000000000000000000000002708 128.0
HFD3_k127_2955019_8 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0001282 46.0
HFD3_k127_2955019_9 PBS lyase HEAT domain protein repeat-containing protein K22221 - - 0.0006445 51.0
HFD3_k127_2963522_0 3-isopropylmalate dehydratase activity K01703 - 4.2.1.33,4.2.1.35 2.133e-199 628.0
HFD3_k127_2963522_1 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007963 533.0
HFD3_k127_2963522_10 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K07713 - - 0.000000000001226 79.0
HFD3_k127_2963522_2 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 418.0
HFD3_k127_2963522_3 HMGL-like K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 309.0
HFD3_k127_2963522_4 Mut7-C ubiquitin K09122 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003943 267.0
HFD3_k127_2963522_5 3-isopropylmalate dehydratase activity K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000001056 211.0
HFD3_k127_2963522_6 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000004079 174.0
HFD3_k127_2963522_7 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000001641 173.0
HFD3_k127_2963522_9 PFAM response regulator receiver - - - 0.0000000000000000003114 98.0
HFD3_k127_2968666_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses K01916,K01950 GO:0003674,GO:0003824,GO:0003952,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016880,GO:0016884,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 1.01e-308 959.0
HFD3_k127_2968666_1 Glycosyl hydrolases family 2, TIM barrel domain - - - 9.632e-221 699.0
HFD3_k127_2968666_2 COG3119 Arylsulfatase A K01134 - 3.1.6.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004613 584.0
HFD3_k127_2968666_3 PFAM Aminotransferase class I and II K05825 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000382 541.0
HFD3_k127_2968666_4 Calcineurin-like phosphoesterase K14379 - 3.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003422 355.0
HFD3_k127_2968666_5 Transposase K07481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 291.0
HFD3_k127_2968666_6 - - - - 0.00000000000000000000000000000000002387 142.0
HFD3_k127_2968666_7 protein-disulfide reductase activity K01829,K04084 - 1.8.1.8,5.3.4.1 0.00000000000000000006348 97.0
HFD3_k127_3021162_0 ASPIC and UnbV - - - 3.61e-242 771.0
HFD3_k127_3021162_1 efflux transmembrane transporter activity - - - 1.861e-198 645.0
HFD3_k127_3021162_10 pfam abc-1 K03688 - - 0.00000000000000000000000000000000000000000000000000000004399 219.0
HFD3_k127_3021162_11 Beta-ketoacyl synthase, C-terminal domain - - - 0.00000000000000000000000000000000000000000002171 181.0
HFD3_k127_3021162_12 PFAM phospholipid glycerol acyltransferase - - - 0.0000000000000000000000000000000000000005391 169.0
HFD3_k127_3021162_13 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000000001035 140.0
HFD3_k127_3021162_14 Sigma-70, region 4 - - - 0.0000000000000001995 89.0
HFD3_k127_3021162_15 ABC1 family K03688 - - 0.0000000000006763 77.0
HFD3_k127_3021162_16 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006643,GO:0006644,GO:0006664,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009245,GO:0009247,GO:0009259,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016053,GO:0019637,GO:0019693,GO:0019752,GO:0019842,GO:0030312,GO:0031177,GO:0032787,GO:0033218,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046483,GO:0046493,GO:0048037,GO:0051186,GO:0051192,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072341,GO:0072521,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901360,GO:1901564,GO:1901576,GO:1903509 - 0.0000001424 58.0
HFD3_k127_3021162_2 beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 495.0
HFD3_k127_3021162_3 TIGRFAM Cell shape determining protein MreB Mrl K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 465.0
HFD3_k127_3021162_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 444.0
HFD3_k127_3021162_5 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 410.0
HFD3_k127_3021162_6 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 361.0
HFD3_k127_3021162_7 Hydroxymethylglutaryl-coenzyme A reductase K00021 - 1.1.1.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004095 305.0
HFD3_k127_3021162_8 COG1233 Phytoene dehydrogenase and related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002371 274.0
HFD3_k127_3021162_9 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009588 259.0
HFD3_k127_3026489_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.0 1087.0
HFD3_k127_3026489_1 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008602 562.0
HFD3_k127_3026489_10 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000002357 200.0
HFD3_k127_3026489_11 ABC transporter, phosphonate, periplasmic substrate-binding protein K02020 - - 0.0000000000000000000000000000000000000000000006724 175.0
HFD3_k127_3026489_12 - K06921 - - 0.00000000000000000000000000000000000000000001404 173.0
HFD3_k127_3026489_13 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000003335 148.0
HFD3_k127_3026489_14 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.00000000000000000000004526 111.0
HFD3_k127_3026489_2 ATP phosphoribosyltransferase K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 405.0
HFD3_k127_3026489_3 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 335.0
HFD3_k127_3026489_4 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006632 305.0
HFD3_k127_3026489_5 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001376 287.0
HFD3_k127_3026489_6 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000001698 258.0
HFD3_k127_3026489_7 Molybdate ABC transporter K02018 - - 0.0000000000000000000000000000000000000000000000000000000000000002562 238.0
HFD3_k127_3026489_8 Belongs to the HisA HisF family K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000315 227.0
HFD3_k127_3026489_9 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000004165 194.0
HFD3_k127_3057632_0 Peptidase family M1 domain - - - 1.51e-249 781.0
HFD3_k127_3057632_1 Alpha-L-fucosidase K01206 - 3.2.1.51 6.316e-206 649.0
HFD3_k127_3057632_10 Signal peptidase (SPase) II K03101 - 3.4.23.36 0.000000000000000000000000000000000000395 147.0
HFD3_k127_3057632_11 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000001849 143.0
HFD3_k127_3057632_12 negative regulation of transcription, DNA-templated K10947 - - 0.000000000000000000000004041 105.0
HFD3_k127_3057632_14 Protein of unknown function (DUF1579) - - - 0.0000000002154 69.0
HFD3_k127_3057632_16 - - - - 0.00000922 57.0
HFD3_k127_3057632_2 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007804 533.0
HFD3_k127_3057632_3 Domain of unknown function (DUF3471) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 501.0
HFD3_k127_3057632_4 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 496.0
HFD3_k127_3057632_5 protein kinase related protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006986 485.0
HFD3_k127_3057632_6 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009693 336.0
HFD3_k127_3057632_7 protein kinase related protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 299.0
HFD3_k127_3057632_8 beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001555 265.0
HFD3_k127_3057632_9 DinB family - - - 0.00000000000000000000000000000000000000003401 158.0
HFD3_k127_306194_0 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009264 300.0
HFD3_k127_306194_1 Beta-lactamase class C and other penicillin binding K01286 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000003148 261.0
HFD3_k127_306194_2 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000006252 231.0
HFD3_k127_306194_3 Mycolic acid cyclopropane synthetase - - - 0.0009726 42.0
HFD3_k127_3077633_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 6.013e-305 954.0
HFD3_k127_3077633_1 Belongs to the glycosyl hydrolase 31 family K07407 - 3.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004507 539.0
HFD3_k127_3077633_2 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 409.0
HFD3_k127_3077633_3 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 389.0
HFD3_k127_3077633_4 CO dehydrogenase flavoprotein C-terminal domain K11178 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 365.0
HFD3_k127_3077633_5 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006553 286.0
HFD3_k127_3077633_6 [2Fe-2S] binding domain K07302,K13483 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000002889 241.0
HFD3_k127_3077633_7 TIR domain - - - 0.00000000000000000000000000000000000000000000006731 186.0
HFD3_k127_3077633_8 PFAM BioY protein K03523 - - 0.000000000000000003842 98.0
HFD3_k127_3077633_9 Putative ABC exporter - - - 0.000001245 60.0
HFD3_k127_3080293_0 Domain of unknown function (DUF5117) - - - 8.592e-313 985.0
HFD3_k127_3080293_1 Major Facilitator Superfamily K02445,K07783 - - 2.035e-216 681.0
HFD3_k127_3080293_10 von Willebrand factor, type A K07114 - - 0.00000000000000000000005919 111.0
HFD3_k127_3080293_11 Heat induced stress protein YflT - - - 0.00000000003913 70.0
HFD3_k127_3080293_12 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000008953 68.0
HFD3_k127_3080293_13 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.0000004049 57.0
HFD3_k127_3080293_2 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 2.355e-202 654.0
HFD3_k127_3080293_3 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 556.0
HFD3_k127_3080293_4 Elongation factor SelB, winged helix K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 510.0
HFD3_k127_3080293_5 glycerophosphodiester phosphodiesterase activity K01126 GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008081,GO:0008889,GO:0009279,GO:0016020,GO:0016787,GO:0016788,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0042578,GO:0042597,GO:0043167,GO:0043169,GO:0044462,GO:0044464,GO:0046872,GO:0071944 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000002715 265.0
HFD3_k127_3080293_6 MOFRL family K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000002288 218.0
HFD3_k127_3080293_7 TIGRFAM geranylgeranyl reductase - - - 0.000000000000000000000000000000000000000000008043 177.0
HFD3_k127_3080293_8 TIGRFAM TonB family protein K03832 - - 0.0000000000000000000000000000542 128.0
HFD3_k127_3080293_9 ECF sigma factor K03088 - - 0.0000000000000000000000002359 115.0
HFD3_k127_3082146_0 Methyl-accepting chemotaxis protein (MCP) signaling domain K02660,K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 386.0
HFD3_k127_3082146_1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02658 - - 0.0000000000000000000000000000000008615 134.0
HFD3_k127_3082146_2 cheY-homologous receiver domain K02657 - - 0.00000000000000000000000000000000156 140.0
HFD3_k127_3082146_3 Two component signalling adaptor domain K03408 - - 0.0000000000000000003506 102.0
HFD3_k127_3082146_4 phosphorelay signal transduction system - - - 0.00002013 55.0
HFD3_k127_3103056_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.15 2.523e-204 646.0
HFD3_k127_3103056_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006054 550.0
HFD3_k127_3103056_2 Required for chromosome condensation and partitioning K03529 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 436.0
HFD3_k127_3103056_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 342.0
HFD3_k127_3103056_4 Catalyzes the oxidation of L-aspartate to iminoaspartate K00239,K00278 - 1.3.5.1,1.3.5.4,1.4.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004103 298.0
HFD3_k127_3103056_5 Peptidase M48 K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000003208 237.0
HFD3_k127_3103056_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000003907 211.0
HFD3_k127_3103056_7 Thrombospondin type 3 repeat - - - 0.00000000000000000004722 105.0
HFD3_k127_3103056_8 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117,K03646 - - 0.0000000000000006129 80.0
HFD3_k127_3103056_9 PFAM blue (type 1) copper domain protein - - - 0.000001305 57.0
HFD3_k127_3108109_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 462.0
HFD3_k127_3108109_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 315.0
HFD3_k127_3108109_2 Belongs to the SEDS family K03588 - - 0.000000001356 59.0
HFD3_k127_3114053_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000793 383.0
HFD3_k127_3114053_1 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000003494 243.0
HFD3_k127_3119305_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K17050 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0042126,GO:0043436,GO:0043546,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0097159,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 0.0 1729.0
HFD3_k127_3119305_1 nitrate reductase beta subunit K00371 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0033554,GO:0042126,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 2.403e-200 654.0
HFD3_k127_3119305_2 Domain of unknown function (DUF4976) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 595.0
HFD3_k127_3119305_3 Major Facilitator Superfamily K02575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 516.0
HFD3_k127_3119305_4 nitrate reductase activity K00370,K00374,K02575 GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006950,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009628,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0036293,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0046906,GO:0048037,GO:0050896,GO:0055114,GO:0070469,GO:0070470,GO:0070482,GO:0071944,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204 1.7.5.1 0.0000000000000000000000000000000000000000002504 173.0
HFD3_k127_3119305_5 Protein of unknown function (DUF1579) - - - 0.000000000000000000000003604 110.0
HFD3_k127_3119305_6 - - - - 0.000000000000000007649 89.0
HFD3_k127_3119305_7 Nitrate reductase delta subunit - - - 0.00000000005321 74.0
HFD3_k127_3122718_0 serine-type peptidase activity K01278 - 3.4.14.5 8.653e-284 888.0
HFD3_k127_3122718_1 Zn-dependent dipeptidase, microsomal dipeptidase K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 516.0
HFD3_k127_3122718_2 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000466 513.0
HFD3_k127_3122718_3 Predicted membrane protein (DUF2339) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 493.0
HFD3_k127_3122718_4 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 432.0
HFD3_k127_3122718_5 Gluconate K03299 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 377.0
HFD3_k127_3122718_6 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009452 329.0
HFD3_k127_3124971_0 Sortilin, neurotensin receptor 3, - - - 6.013e-292 926.0
HFD3_k127_3124971_1 efflux transmembrane transporter activity K02004 - - 2.496e-196 643.0
HFD3_k127_3124971_10 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001055 281.0
HFD3_k127_3124971_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002052 257.0
HFD3_k127_3124971_12 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000006872 136.0
HFD3_k127_3124971_13 secondary active sulfate transmembrane transporter activity - - - 0.00000000000000000000000000000000652 136.0
HFD3_k127_3124971_14 Fatty acid desaturase K00496 - 1.14.15.3 0.000000000000000000000000000000366 126.0
HFD3_k127_3124971_15 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.0000000000000000000000000000004955 132.0
HFD3_k127_3124971_16 - - - - 0.00000000000000000000000000002426 125.0
HFD3_k127_3124971_17 Transcriptional regulator PadR-like family - - - 0.0000000000000000000001194 103.0
HFD3_k127_3124971_18 Protein of unknown function (DUF3667) - - - 0.0000000000000000000002372 113.0
HFD3_k127_3124971_19 Type II secretion system (T2SS), protein F K12511 - - 0.000007373 57.0
HFD3_k127_3124971_2 Tricorn protease homolog - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 574.0
HFD3_k127_3124971_20 RDD family - - - 0.0006876 51.0
HFD3_k127_3124971_3 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 464.0
HFD3_k127_3124971_4 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 486.0
HFD3_k127_3124971_5 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 441.0
HFD3_k127_3124971_6 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005451 376.0
HFD3_k127_3124971_7 DUF218 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 319.0
HFD3_k127_3124971_8 Dipeptidyl-peptidase 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 333.0
HFD3_k127_3124971_9 Tricorn protease homolog - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004075 308.0
HFD3_k127_3136705_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 433.0
HFD3_k127_3136705_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003724 324.0
HFD3_k127_3136705_2 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 306.0
HFD3_k127_3136705_3 Transposase K07481 - - 0.0000000000000000001015 100.0
HFD3_k127_3136705_4 Belongs to the sulfur carrier protein TusA family - - - 0.000000009193 62.0
HFD3_k127_3147207_0 Fg-gap repeat K18197 - 4.2.2.23 6.202e-250 795.0
HFD3_k127_3147207_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 382.0
HFD3_k127_3147207_10 TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.000000000000000000000000000000000007221 142.0
HFD3_k127_3147207_11 RNA polymerase-binding protein DksA K06204 - - 0.0000000000000001163 84.0
HFD3_k127_3147207_12 peptidyl-tyrosine sulfation - - - 0.00000007337 66.0
HFD3_k127_3147207_14 VanZ like family - - - 0.000683 47.0
HFD3_k127_3147207_2 metallophosphoesterase K07096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 320.0
HFD3_k127_3147207_3 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000569 304.0
HFD3_k127_3147207_4 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000402 311.0
HFD3_k127_3147207_5 peptidoglycan-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006226 291.0
HFD3_k127_3147207_6 ABC transporter K02003 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000005243 259.0
HFD3_k127_3147207_7 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000000000000000009016 218.0
HFD3_k127_3147207_8 lipolytic protein G-D-S-L family K10804 GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564 3.1.1.5 0.00000000000000000000000000000000000000000000000000000001184 205.0
HFD3_k127_3147207_9 Peptidase family M23 K21472 - - 0.000000000000000000000000000000000000000000000000001857 192.0
HFD3_k127_314935_0 Prolyl oligopeptidase family - - - 6.948e-262 827.0
HFD3_k127_314935_1 Tetratricopeptide repeat K12132 - 2.7.11.1 5.456e-197 645.0
HFD3_k127_314935_10 Putative restriction endonuclease - - - 0.000000000000000000000000442 112.0
HFD3_k127_314935_11 Alcohol dehydrogenase GroES-like domain K00001 - 1.1.1.1 0.00000000000000000008626 93.0
HFD3_k127_314935_12 - - - - 0.000001436 53.0
HFD3_k127_314935_14 PhoD-like phosphatase, N-terminal domain K01113 - 3.1.3.1 0.0003371 47.0
HFD3_k127_314935_15 Conjugative relaxase domain protein - - - 0.0008134 46.0
HFD3_k127_314935_2 Aminotransferase class-III K00823 - 2.6.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 520.0
HFD3_k127_314935_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003732 465.0
HFD3_k127_314935_4 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 319.0
HFD3_k127_314935_5 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000002841 230.0
HFD3_k127_314935_6 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000002126 175.0
HFD3_k127_314935_8 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000001182 138.0
HFD3_k127_314935_9 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000000001996 111.0
HFD3_k127_3155419_0 Glycosyl hydrolases family 15 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008828 302.0
HFD3_k127_3155419_1 Isochorismatase family K08281 - 3.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000005537 267.0
HFD3_k127_3155419_2 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 0.0000000000000000000000000000000000000000000000000006841 193.0
HFD3_k127_3171655_0 efflux transmembrane transporter activity - - - 1.739e-218 704.0
HFD3_k127_3171655_1 6-phosphofructokinase activity K00850,K00895,K21071 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008443,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0046872,GO:0047334,GO:0071704,GO:1901135 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000001416 133.0
HFD3_k127_3171928_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 2.171e-271 850.0
HFD3_k127_3171928_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000003879 177.0
HFD3_k127_3189965_0 Tripartite tricarboxylate transporter TctA family - - - 1.761e-195 627.0
HFD3_k127_3189965_1 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003811 402.0
HFD3_k127_3189965_10 SnoaL-like domain - - - 0.0000000004254 73.0
HFD3_k127_3189965_11 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.00000003801 58.0
HFD3_k127_3189965_2 spermidine synthase activity K00797 GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 380.0
HFD3_k127_3189965_3 Protein of unknown function (DUF1343) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006031 361.0
HFD3_k127_3189965_4 region 4 type 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001375 277.0
HFD3_k127_3189965_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000126 230.0
HFD3_k127_3189965_6 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000000000003722 130.0
HFD3_k127_3189965_7 - - - - 0.000000000000000000000000000001501 124.0
HFD3_k127_3189965_8 Thioredoxin-like - - - 0.00000000000000000000000000001039 125.0
HFD3_k127_3189965_9 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000004715 90.0
HFD3_k127_3195089_0 Integrase core domain K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 445.0
HFD3_k127_3195089_1 Transposase - - - 0.000000000000000000000000007347 115.0
HFD3_k127_3195089_2 ATPase (AAA superfamily K07133 - - 0.0000000000001982 75.0
HFD3_k127_3207589_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006241 442.0
HFD3_k127_3207589_1 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000002961 256.0
HFD3_k127_3207589_2 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003603 260.0
HFD3_k127_3207589_3 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000002637 246.0
HFD3_k127_3207589_4 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.0000000000000000000008653 100.0
HFD3_k127_3207589_5 PFAM TonB-dependent Receptor K16091 - - 0.0000000007759 72.0
HFD3_k127_3207589_6 TonB dependent receptor K02014 - - 0.0000004482 63.0
HFD3_k127_3210263_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 531.0
HFD3_k127_3210263_1 domain protein K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 373.0
HFD3_k127_3210263_2 ThiS family K03636 - - 0.000000000000000000005875 96.0
HFD3_k127_3220109_0 ATP synthesis coupled electron transport K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008392 362.0
HFD3_k127_3220109_1 Cytochrome C biogenesis protein transmembrane region K04084 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006253 347.0
HFD3_k127_3220109_2 aminopeptidase - - - 0.000000000000000000000000000000000000000000000000007051 201.0
HFD3_k127_3220109_3 lipid kinase, YegS Rv2252 BmrU family - - - 0.000000000000000000000000000000000000000003749 166.0
HFD3_k127_3223519_0 4 iron, 4 sulfur cluster binding - - - 9.418e-208 658.0
HFD3_k127_3223519_1 Prolipoprotein diacylglyceryl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000007221 226.0
HFD3_k127_3223519_2 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000002913 102.0
HFD3_k127_3225419_0 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002506 582.0
HFD3_k127_3225419_1 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004519 291.0
HFD3_k127_3225419_2 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000786 162.0
HFD3_k127_3225419_3 Protein of unknown function (DUF1684) K09164 - - 0.000000000000000000000000000000000000001905 154.0
HFD3_k127_3225419_4 PFAM Prenyltransferase squalene oxidase - - - 0.00000000000000000000000002472 121.0
HFD3_k127_3225634_0 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007134 286.0
HFD3_k127_3225634_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000005773 70.0
HFD3_k127_3225634_2 Glycosyl transferase family 2 - - - 0.00000005735 55.0
HFD3_k127_3240798_0 COG0187 Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) B subunit K02470,K02622 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004191 527.0
HFD3_k127_3247842_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 0.0 1090.0
HFD3_k127_3247842_1 nitrite transmembrane transporter activity - - - 8.581e-320 994.0
HFD3_k127_3247842_2 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 550.0
HFD3_k127_3247842_3 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000288 284.0
HFD3_k127_3247842_4 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000000001781 165.0
HFD3_k127_3247842_5 TPR repeat - - - 0.0000000000000001159 93.0
HFD3_k127_3248586_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 559.0
HFD3_k127_3248586_1 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 479.0
HFD3_k127_3248586_2 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005295 404.0
HFD3_k127_3248586_3 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 376.0
HFD3_k127_3248586_4 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002931 358.0
HFD3_k127_3248586_5 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009298 292.0
HFD3_k127_3248586_6 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005412 275.0
HFD3_k127_3248586_7 Putative cyclase K07130 - 3.5.1.9 0.0000000000000000000000000000000000000000000000000000000000001016 226.0
HFD3_k127_3248586_8 Carboxypeptidase regulatory-like domain - - - 0.0006734 53.0
HFD3_k127_3250964_0 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000000008992 254.0
HFD3_k127_3250964_1 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000009679 141.0
HFD3_k127_3250964_2 Sigma-70, region 4 K03088 GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.0000000000000000003495 94.0
HFD3_k127_3250964_3 AntiSigma factor - - - 0.0006451 50.0
HFD3_k127_3252321_0 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 610.0
HFD3_k127_3252321_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000001083 205.0
HFD3_k127_3252321_2 Carboxypeptidase regulatory-like domain - - - 0.0000000000004103 76.0
HFD3_k127_3256238_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004524 554.0
HFD3_k127_3256238_1 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005492 516.0
HFD3_k127_3256238_2 PFAM aminotransferase, class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 361.0
HFD3_k127_3256238_3 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000008225 208.0
HFD3_k127_3256238_4 AI-2E family transporter K03548 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.0000000000000000000000000000000000000001923 163.0
HFD3_k127_3256238_5 Belongs to the ompA family - - - 0.0000000000000000000000000003298 131.0
HFD3_k127_3256238_6 TIGRFAM VWFA-related Acidobacterial domain - - - 0.0000000000000000000008497 109.0
HFD3_k127_3256238_8 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00001453 58.0
HFD3_k127_3256238_9 aminopeptidase - - - 0.0009609 51.0
HFD3_k127_3259061_0 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000958 616.0
HFD3_k127_3259061_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005289 576.0
HFD3_k127_3259061_2 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K22319 - 6.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009572 392.0
HFD3_k127_3259061_3 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000002109 215.0
HFD3_k127_3285502_0 ATPase activity K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003222 266.0
HFD3_k127_3285502_1 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.29 0.0000000000000000000000000000000000000000000000000000000004727 209.0
HFD3_k127_3285502_2 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000004487 159.0
HFD3_k127_3339382_0 Radical SAM - - - 0.0 1137.0
HFD3_k127_3339382_1 Beta-L-arabinofuranosidase, GH127 K09955 - - 0.0 1099.0
HFD3_k127_3339382_10 Oxidoreductase molybdopterin binding domain K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004618 419.0
HFD3_k127_3339382_11 FGGY family of carbohydrate kinases, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003798 404.0
HFD3_k127_3339382_12 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005573 400.0
HFD3_k127_3339382_13 COGs COG1129 ABC-type sugar transport system ATPase component K10441 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007678 402.0
HFD3_k127_3339382_14 helix_turn _helix lactose operon repressor K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005107 333.0
HFD3_k127_3339382_15 Inner membrane protein CreD K06143 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005991 342.0
HFD3_k127_3339382_16 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006254 285.0
HFD3_k127_3339382_17 Pfam Class II Aldolase and Adducin N-terminal domain K03077 - 5.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000007749 257.0
HFD3_k127_3339382_18 COG0642 Signal transduction histidine kinase K14980 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000008448 251.0
HFD3_k127_3339382_19 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K14981 - - 0.00000000000000000000000000000000000000000000000000000000000000001065 232.0
HFD3_k127_3339382_2 Alpha-L-arabinofuranosidase C-terminal domain K01209 - 3.2.1.55 1.164e-244 767.0
HFD3_k127_3339382_20 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.000000000000000000000000000000000000000000000000000000000000009672 221.0
HFD3_k127_3339382_21 ABC-type sugar transport system periplasmic component K10439 - - 0.000000000000000000000000000000000000000000000000000000001582 213.0
HFD3_k127_3339382_22 Belongs to the binding-protein-dependent transport system permease family K10440,K17206 - - 0.0000000000000000000000000000000000000000006701 181.0
HFD3_k127_3339382_23 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K01838 - 5.4.2.6 0.000000000000000000000000000000000000000006189 169.0
HFD3_k127_3339382_24 Transcriptional regulator K07979 - - 0.00000000000000000000000000000000000001373 148.0
HFD3_k127_3339382_25 His Kinase A (phosphoacceptor) domain - - - 0.00000000008312 75.0
HFD3_k127_3339382_26 - - - - 0.000000003992 66.0
HFD3_k127_3339382_3 PFAM glycoside hydrolase family 39 K01198 - 3.2.1.37 4.641e-239 753.0
HFD3_k127_3339382_4 FGGY family of carbohydrate kinases, C-terminal domain K00853 - 2.7.1.16 7.622e-221 699.0
HFD3_k127_3339382_5 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 617.0
HFD3_k127_3339382_6 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004745 612.0
HFD3_k127_3339382_7 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 542.0
HFD3_k127_3339382_8 Converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 470.0
HFD3_k127_3339382_9 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000532 434.0
HFD3_k127_3347722_0 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000000000000004438 137.0
HFD3_k127_3347722_1 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000007845 131.0
HFD3_k127_3347722_2 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000007992 119.0
HFD3_k127_3347722_3 membrane - - - 0.000000000000000000000004568 114.0
HFD3_k127_3348013_0 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 1.208e-237 749.0
HFD3_k127_3348013_1 Beta-lactamase superfamily domain - - - 0.0000000000000001064 80.0
HFD3_k127_3376954_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005949 372.0
HFD3_k127_3376954_1 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 348.0
HFD3_k127_3376954_2 - K12065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 314.0
HFD3_k127_3376954_3 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000001529 153.0
HFD3_k127_3376954_4 membrane - - - 0.00000000000000000000000000006312 119.0
HFD3_k127_3376954_5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.000000000000000000000000009765 117.0
HFD3_k127_3376954_6 FMN binding K03612 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000002926 119.0
HFD3_k127_3376954_7 Protein of unknown function (DUF3347) - - - 0.00000000004339 70.0
HFD3_k127_3376954_9 - - - - 0.00001064 57.0
HFD3_k127_3400311_0 long-chain fatty acid transporting porin activity K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000001935 240.0
HFD3_k127_3400311_1 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000014 82.0
HFD3_k127_3408145_0 Belongs to the thiolase family K00632 - 2.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006197 489.0
HFD3_k127_3408145_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K07516 - 1.1.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 420.0
HFD3_k127_3408145_2 hydrolase of the alpha beta K07018 - - 0.00000000000000000000000000000000000000009536 158.0
HFD3_k127_3408145_3 PFAM Alpha beta hydrolase K01055 - 3.1.1.24 0.0000000000000000724 90.0
HFD3_k127_3415679_0 Methionine synthase K00548 - 2.1.1.13 8.84e-216 679.0
HFD3_k127_3415679_1 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007434 490.0
HFD3_k127_3415679_10 HlyD membrane-fusion protein of T1SS - - - 0.0000000000000000009741 99.0
HFD3_k127_3415679_11 40-residue YVTN family beta-propeller repeat - - - 0.00000000000002471 84.0
HFD3_k127_3415679_12 efflux transmembrane transporter activity - - - 0.00000000264 66.0
HFD3_k127_3415679_13 FtsX-like permease family - - - 0.0000003706 59.0
HFD3_k127_3415679_2 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006275 454.0
HFD3_k127_3415679_3 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006909 341.0
HFD3_k127_3415679_4 NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 301.0
HFD3_k127_3415679_5 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000004946 246.0
HFD3_k127_3415679_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000001023 246.0
HFD3_k127_3415679_7 HlyD family secretion protein - - - 0.000000000000000000000000000000000000000000004713 185.0
HFD3_k127_3415679_8 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000006663 136.0
HFD3_k127_3415679_9 SnoaL-like domain K06893 - - 0.00000000000000000000002418 104.0
HFD3_k127_3453919_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 2.781e-254 794.0
HFD3_k127_3453919_1 Histidine ammonia-lyase K01745 - 4.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005387 492.0
HFD3_k127_3453919_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000457 457.0
HFD3_k127_3453919_3 Domain of unknown function (DUF4142) K08995 - - 0.000000000000000000000000002776 128.0
HFD3_k127_3490467_0 PFAM Catalase domain protein K03781 - 1.11.1.6 5.261e-290 895.0
HFD3_k127_3490467_1 Beta-L-arabinofuranosidase, GH127 - - - 1.343e-230 733.0
HFD3_k127_3490467_2 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000094 309.0
HFD3_k127_3490467_3 PQQ enzyme repeat K00114 - 1.1.2.8 0.00000001771 64.0
HFD3_k127_3494534_0 proline dipeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 603.0
HFD3_k127_3494534_1 AAA ATPase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 577.0
HFD3_k127_3494534_10 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001279 281.0
HFD3_k127_3494534_11 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005392 258.0
HFD3_k127_3494534_12 Tetratricopeptide repeat K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000006771 240.0
HFD3_k127_3494534_2 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000372 481.0
HFD3_k127_3494534_3 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 436.0
HFD3_k127_3494534_4 Putative esterase K07214 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009346 396.0
HFD3_k127_3494534_5 alcohol dehydrogenase K00001,K00008 - 1.1.1.1,1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 381.0
HFD3_k127_3494534_6 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 361.0
HFD3_k127_3494534_7 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 334.0
HFD3_k127_3494534_8 Orotidine 5'-phosphate decarboxylase / HUMPS family K08093 - 4.1.2.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000655 310.0
HFD3_k127_3494534_9 PLD-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001641 284.0
HFD3_k127_3500715_0 Methyl-accepting chemotaxis protein (MCP) signaling domain K02660,K03406 - - 0.00000000000000000000000000000000000000000000000000002084 204.0
HFD3_k127_3500715_1 Two component signalling adaptor domain K03408 - - 0.000000000000000000003828 105.0
HFD3_k127_3515226_0 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000003778 252.0
HFD3_k127_3515226_1 acyl-CoA thioester hydrolase, YbgC YbaW family K07107 - - 0.0000000000000000000000000000001159 131.0
HFD3_k127_3515226_2 PASTA domain K12132 - 2.7.11.1 0.000000000000000001038 93.0
HFD3_k127_3515226_3 Polysaccharide biosynthesis protein K01784,K08679 - 5.1.3.2,5.1.3.6 0.0000000000000005609 80.0
HFD3_k127_3529255_0 isomerase K01820 - 5.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007178 550.0
HFD3_k127_3529255_1 Carboxypeptidase regulatory-like domain - - - 0.0001411 45.0
HFD3_k127_3536884_0 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.00000000000000001398 86.0
HFD3_k127_3536884_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000004154 75.0
HFD3_k127_3536884_2 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000004399 62.0
HFD3_k127_3550374_0 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 7.259e-244 757.0
HFD3_k127_3550374_1 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 5.832e-224 712.0
HFD3_k127_3550374_10 Probably functions as a manganese efflux pump - - - 0.00000000000000000000000000000000000000000000000000000001461 220.0
HFD3_k127_3550374_11 pyrroloquinoline quinone binding - - - 0.00000000000000000000000000000000000000000000000005658 188.0
HFD3_k127_3550374_12 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000007918 145.0
HFD3_k127_3550374_13 integral membrane protein - - - 0.0000000000000000000000005015 120.0
HFD3_k127_3550374_14 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000005927 85.0
HFD3_k127_3550374_15 Uncharacterised protein family (UPF0182) K09118 - - 0.000000000003674 70.0
HFD3_k127_3550374_16 Protein conserved in bacteria K15539 - - 0.00000003041 64.0
HFD3_k127_3550374_2 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 524.0
HFD3_k127_3550374_3 Serves to protect cells from the toxic effects of hydrogen peroxide K03781 - 1.11.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007561 482.0
HFD3_k127_3550374_4 Penicillin-binding Protein K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 406.0
HFD3_k127_3550374_5 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009733 386.0
HFD3_k127_3550374_6 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007748 316.0
HFD3_k127_3550374_7 Glycosyl hydrolase family 10 K01181 - 3.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004703 293.0
HFD3_k127_3550374_8 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001188 283.0
HFD3_k127_3570157_0 G-rich domain on putative tyrosine kinase K16554,K16692 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 310.0
HFD3_k127_3570157_1 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000009188 188.0
HFD3_k127_3570157_2 transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000004722 166.0
HFD3_k127_3570157_3 PRMT5 arginine-N-methyltransferase K11434 - 2.1.1.319 0.000000000000000000000000000000006745 143.0
HFD3_k127_3570157_4 O-Antigen ligase K02847 - - 0.00000000000000000000123 109.0
HFD3_k127_3570157_5 Nodulation protein S (NodS) - - - 0.0000000000000000002929 102.0
HFD3_k127_3570157_6 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.0000000000000001063 93.0
HFD3_k127_3570157_8 Methyltransferase - - - 0.0000000000000004981 89.0
HFD3_k127_3571788_0 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 437.0
HFD3_k127_3571788_1 mannose-ethanolamine phosphotransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 375.0
HFD3_k127_3571788_2 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008572 319.0
HFD3_k127_3571788_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008582 331.0
HFD3_k127_3571788_4 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000002901 242.0
HFD3_k127_3571788_5 conserved protein (COG2071) K09166 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009308 246.0
HFD3_k127_3571788_6 COG0436 Aspartate tyrosine aromatic aminotransferase - - - 0.0000000001253 74.0
HFD3_k127_3571788_7 SMART Transport-associated and nodulation - - - 0.0000001628 60.0
HFD3_k127_3585588_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000703 419.0
HFD3_k127_3585588_1 DnaJ central domain K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008109 407.0
HFD3_k127_3585588_2 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814,K05365 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006227 277.0
HFD3_k127_3585588_3 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000007025 217.0
HFD3_k127_3585588_4 XdhC and CoxI family K07402 - - 0.00000000000000000000000000000000000000000000000000000001862 212.0
HFD3_k127_3585588_5 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000009662 132.0
HFD3_k127_3585588_6 Methylates ribosomal protein L11 K02687 - - 0.0000000000000000000000000005984 125.0
HFD3_k127_3585588_7 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0002298 52.0
HFD3_k127_3595657_0 Acyl-CoA dehydrogenase, C-terminal domain K16173 - 1.3.99.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 502.0
HFD3_k127_3595657_1 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 433.0
HFD3_k127_3595657_10 Belongs to the peptidase S11 family K01286,K07258,K07262 GO:0000003,GO:0000270,GO:0000910,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0006022,GO:0006508,GO:0006807,GO:0007049,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016043,GO:0016787,GO:0019538,GO:0019954,GO:0022402,GO:0022414,GO:0030203,GO:0032505,GO:0042221,GO:0042493,GO:0042597,GO:0043093,GO:0043170,GO:0044238,GO:0044464,GO:0045229,GO:0050896,GO:0051301,GO:0070011,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0140096,GO:1901135,GO:1901564 3.4.16.4 0.0000000000000000000000000000000000000004707 162.0
HFD3_k127_3595657_11 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000009297 144.0
HFD3_k127_3595657_12 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.00000000000000000000000000001678 126.0
HFD3_k127_3595657_13 Polymer-forming cytoskeletal - - - 0.00000000000000000000000003346 119.0
HFD3_k127_3595657_14 Necessary for formate dehydrogenase activity K02380 - - 0.00000000000000001462 93.0
HFD3_k127_3595657_15 PFAM DNA methylase N-4 N-6 domain protein K00571 - 2.1.1.72 0.00000000009358 66.0
HFD3_k127_3595657_16 methyltransferase - - - 0.0000000001528 73.0
HFD3_k127_3595657_17 beta-lactamase - - - 0.000001933 61.0
HFD3_k127_3595657_18 Tetratricopeptide TPR_2 repeat protein - - - 0.00003112 57.0
HFD3_k127_3595657_19 protein with the myosin-like domain - - - 0.0005841 51.0
HFD3_k127_3595657_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 441.0
HFD3_k127_3595657_3 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03671,K22345 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9,4.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 429.0
HFD3_k127_3595657_4 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009706 407.0
HFD3_k127_3595657_5 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007812 390.0
HFD3_k127_3595657_6 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006703 366.0
HFD3_k127_3595657_7 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000000000000000000000000000000001399 227.0
HFD3_k127_3595657_8 Transporter major facilitator family protein - - - 0.00000000000000000000000000000000000000000000000003381 194.0
HFD3_k127_3595657_9 Belongs to the SUA5 family K07566 - 2.7.7.87 0.000000000000000000000000000000000000000378 156.0
HFD3_k127_3603513_0 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008052 466.0
HFD3_k127_3603513_1 Intracellular protease, PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007275 317.0
HFD3_k127_3603513_2 COGs COG4299 conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002216 278.0
HFD3_k127_3603513_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000001745 247.0
HFD3_k127_3603513_4 DinB family - - - 0.00000000000000000000000000000000000000000000000000000000001203 211.0
HFD3_k127_3603513_5 YCII-related domain - - - 0.00000000000000000000000000000000000002384 149.0
HFD3_k127_3603513_6 Putative ABC exporter - - - 0.00000000000000000002809 101.0
HFD3_k127_3603513_7 - - - - 0.0000000000000000001008 96.0
HFD3_k127_3603513_8 Lipid A oxidase (Involved in formation of 2-aminogluconate) protein K12980 - - 0.0000000002702 74.0
HFD3_k127_3619601_0 COG3666 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005066 402.0
HFD3_k127_3619601_1 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000038 225.0
HFD3_k127_3619601_2 Cation efflux family - - - 0.00000000000000000000000000000000000000004047 156.0
HFD3_k127_3639954_0 Domain of unknown function (DUF4445) - - - 1.607e-237 750.0
HFD3_k127_3639954_1 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 1.461e-206 648.0
HFD3_k127_3639954_10 cobalamin binding - - - 0.00000000000000000000000002374 113.0
HFD3_k127_3639954_11 - - - - 0.0000000188 61.0
HFD3_k127_3639954_2 B12 binding domain - - - 6.676e-194 614.0
HFD3_k127_3639954_3 Glycosyl hydrolase family 20, catalytic domain K12373 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 479.0
HFD3_k127_3639954_4 Homocysteine S-methyltransferase K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006442 476.0
HFD3_k127_3639954_5 methionine synthase K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007438 484.0
HFD3_k127_3639954_6 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007107 458.0
HFD3_k127_3639954_7 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 376.0
HFD3_k127_3639954_8 - - - - 0.0000000000000000000000000000000000003455 148.0
HFD3_k127_3639954_9 von Willebrand factor, type A K07114 - - 0.000000000000000000000000008085 122.0
HFD3_k127_36811_0 AcrB/AcrD/AcrF family K03296 - - 0.0 1257.0
HFD3_k127_36811_1 belongs to the aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003374 492.0
HFD3_k127_36811_2 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 450.0
HFD3_k127_36811_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 311.0
HFD3_k127_36811_4 Putative restriction endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000001817 217.0
HFD3_k127_36811_5 Molecular chaperone. Has ATPase activity K04079 - - 0.00005296 56.0
HFD3_k127_3723607_0 cellular manganese ion homeostasis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 336.0
HFD3_k127_3723607_1 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004145 310.0
HFD3_k127_3723607_2 Na+/H+ antiporter 1 K03313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 314.0
HFD3_k127_3723607_3 Belongs to the pyruvate kinase family K00873 GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001314 291.0
HFD3_k127_3723607_4 Protein of unknown function (DUF1343) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001727 261.0
HFD3_k127_3723607_5 DinB superfamily - - - 0.0000000000000000000000000005167 120.0
HFD3_k127_3723607_6 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000423 75.0
HFD3_k127_3723607_7 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00004529 55.0
HFD3_k127_3773686_0 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 386.0
HFD3_k127_3773686_1 Belongs to the RtcB family K14415 - 6.5.1.3 0.000000000000000000000000000000000000000000002702 166.0
HFD3_k127_3773686_2 Histidine kinase K10942 - 2.7.13.3 0.0000000000000000000001346 105.0
HFD3_k127_3806162_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 1.309e-247 784.0
HFD3_k127_3806162_1 MatE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000054 549.0
HFD3_k127_3806162_2 PFAM 2Fe-2S -binding K03518,K07302,K13483 - 1.2.5.3,1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000005496 217.0
HFD3_k127_3806162_3 ARD/ARD' family - - - 0.000001997 58.0
HFD3_k127_3806162_4 - - - - 0.00002766 53.0
HFD3_k127_383348_0 Sodium:alanine symporter family K03310 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003983 386.0
HFD3_k127_383348_1 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008146 274.0
HFD3_k127_3882107_0 FAD dependent oxidoreductase K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 323.0
HFD3_k127_3882107_1 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001293 280.0
HFD3_k127_3882107_2 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000009719 196.0
HFD3_k127_3900418_0 UvrD REP helicase K03657,K16898 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000006984 292.0
HFD3_k127_3900418_1 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000000000004471 190.0
HFD3_k127_3900418_2 DnaJ molecular chaperone homology domain K05516 - - 0.0000000000000000000375 93.0
HFD3_k127_3915095_0 Alpha-L-arabinofuranosidase C-terminal domain K01209 - 3.2.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 556.0
HFD3_k127_3915095_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007629 449.0
HFD3_k127_3915095_10 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000002691 179.0
HFD3_k127_3915095_11 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000005459 123.0
HFD3_k127_3915095_12 Alkyl hydroperoxide reductase - - - 0.0000002924 53.0
HFD3_k127_3915095_14 Redoxin K03564 - 1.11.1.15 0.0001568 48.0
HFD3_k127_3915095_2 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K11779,K11784,K18285 - 1.21.98.1,2.5.1.120,2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 447.0
HFD3_k127_3915095_3 MoeA N-terminal region (domain I and II) K03750,K07219 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 403.0
HFD3_k127_3915095_4 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003969 392.0
HFD3_k127_3915095_5 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 317.0
HFD3_k127_3915095_6 TonB-dependent Receptor Plug Domain K02014,K16092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004699 325.0
HFD3_k127_3915095_7 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001496 271.0
HFD3_k127_3915095_8 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems ATPase K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000002909 210.0
HFD3_k127_3915095_9 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.000000000000000000000000000000000000000000000105 181.0
HFD3_k127_3937659_0 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 310.0
HFD3_k127_3937659_1 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000172 110.0
HFD3_k127_3937659_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.00000000000000000005568 89.0
HFD3_k127_3937659_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.0000000000000003768 87.0
HFD3_k127_3937659_4 ATP synthase B/B' CF(0) K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000004718 61.0
HFD3_k127_3937659_5 Belongs to the ParB family K03497 - - 0.000001696 50.0
HFD3_k127_3945010_0 Zinc-uptake complex component A periplasmic K02077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 407.0
HFD3_k127_3945010_1 ABC 3 transport family K02075 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 380.0
HFD3_k127_3945010_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 329.0
HFD3_k127_3945010_3 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000008253 197.0
HFD3_k127_3945703_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 490.0
HFD3_k127_3945703_1 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000005437 205.0
HFD3_k127_3945703_2 TIGRFAM VWFA-related Acidobacterial domain - - - 0.0001582 55.0
HFD3_k127_3957968_0 Alanine dehydrogenase/PNT, N-terminal domain K00324 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006448 424.0
HFD3_k127_3957968_1 Hydrolase, alpha beta domain protein K06889 - - 0.000000000000000000000000000000000001187 157.0
HFD3_k127_3957968_2 NAD(P)+ transhydrogenase (AB-specific) activity K00324 - 1.6.1.2 0.0000000000002091 82.0
HFD3_k127_3959036_0 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 478.0
HFD3_k127_3959036_1 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000000006223 161.0
HFD3_k127_3959036_2 PFAM polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000001472 154.0
HFD3_k127_3959036_3 Glycosyltransferase family 9 (heptosyltransferase) K02841 - - 0.000000000000000000000000000001286 135.0
HFD3_k127_3959036_4 methyltransferase - - - 0.000000000000005126 84.0
HFD3_k127_3959036_5 UDP-N-acetylglucosamine 2-epimerase - - - 0.000000001865 72.0
HFD3_k127_3960962_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 4.25e-225 728.0
HFD3_k127_3960962_1 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009371 314.0
HFD3_k127_3960962_2 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009112 291.0
HFD3_k127_3960962_3 Domain of unknown function (DUF892) - - - 0.0000000000000000000000000000000000000000000000005627 179.0
HFD3_k127_3960962_4 NmrA-like family K15891 - 1.1.1.354 0.0000000000000000000000000000000000000002675 156.0
HFD3_k127_3960962_5 Belongs to the UPF0301 (AlgH) family K07735 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000007688 88.0
HFD3_k127_3960962_6 Belongs to the UPF0301 (AlgH) family K07735 - - 0.0000009853 51.0
HFD3_k127_3981042_0 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 398.0
HFD3_k127_3981042_1 Belongs to the LDH2 MDH2 oxidoreductase family K08092 - 1.1.1.130 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007691 396.0
HFD3_k127_3981042_2 testosterone 17-beta-dehydrogenase (NADP+) activity K00826 GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0006694,GO:0006703,GO:0006706,GO:0008150,GO:0008152,GO:0008202,GO:0008210,GO:0008610,GO:0009056,GO:0009058,GO:0009987,GO:0010817,GO:0016042,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0033764,GO:0034754,GO:0042445,GO:0042446,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044424,GO:0044444,GO:0044464,GO:0047045,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 327.0
HFD3_k127_3981042_3 Protein of unknown function (DUF3500) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000168 280.0
HFD3_k127_3981042_4 Inositol oxygenase K00469 - 1.13.99.1 0.0000000000000000000000000000000000000000000000000000000000000001425 229.0
HFD3_k127_4019162_0 beta-galactosidase activity - - - 1.833e-321 1002.0
HFD3_k127_4019162_1 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 357.0
HFD3_k127_4019162_2 peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000008994 257.0
HFD3_k127_4089662_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 5.668e-211 671.0
HFD3_k127_4089662_1 converts alpha-aldose to the beta-anomer - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009739 435.0
HFD3_k127_4089662_2 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005378 403.0
HFD3_k127_4089662_3 cell wall glycoprotein biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001293 256.0
HFD3_k127_4089662_4 Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000005993 231.0
HFD3_k127_4106003_0 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003577 490.0
HFD3_k127_4106003_1 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 394.0
HFD3_k127_4106003_2 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 333.0
HFD3_k127_4106003_3 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000001865 236.0
HFD3_k127_4106003_4 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000004434 207.0
HFD3_k127_4106003_5 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000000000000000000000005179 177.0
HFD3_k127_4106003_6 CheD chemotactic sensory transduction K03411 - 3.5.1.44 0.0000000000000000000000000000000004205 139.0
HFD3_k127_4106003_7 GGDEF domain K03413 - - 0.0000000000000000000007011 107.0
HFD3_k127_4121812_0 Glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 1977.0
HFD3_k127_4121812_1 Flavin containing amine oxidoreductase K00266 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 1.404e-220 693.0
HFD3_k127_4121812_2 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 7.298e-199 641.0
HFD3_k127_4121812_3 Ammonium Transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 574.0
HFD3_k127_4121812_4 - - - - 0.0000000000000000000000001106 124.0
HFD3_k127_4137694_0 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006167 396.0
HFD3_k127_4137694_1 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 331.0
HFD3_k127_4137694_2 oxidoreductase activity - - - 0.000000000000000002553 100.0
HFD3_k127_4137694_3 peptidase activity, acting on L-amino acid peptides K14647,K20276,K21449 - - 0.00000000000005131 80.0
HFD3_k127_4137694_4 - - - - 0.0000000000002415 84.0
HFD3_k127_4137694_5 peptidyl-tyrosine sulfation - - - 0.0000001484 63.0
HFD3_k127_4178784_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 524.0
HFD3_k127_4178784_1 Two component regulator propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 448.0
HFD3_k127_4178784_10 SnoaL-like polyketide cyclase K06893 - - 0.0000000000258 72.0
HFD3_k127_4178784_11 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00003565 55.0
HFD3_k127_4178784_2 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003888 349.0
HFD3_k127_4178784_3 Phosphotriesterase family K07048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006733 321.0
HFD3_k127_4178784_4 Belongs to the glycosyl hydrolase 31 family K07407 - 3.2.1.22 0.00000000000000000000000000000000000000000000000000000000000003909 226.0
HFD3_k127_4178784_5 phosphoserine phosphatase activity K07315,K16928 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000311 220.0
HFD3_k127_4178784_6 response regulator - - - 0.000000000000000000000000000000000000000000000000000001193 199.0
HFD3_k127_4178784_7 Dna alkylation repair - - - 0.000000000000000000000000000000000000000000302 168.0
HFD3_k127_4178784_8 PFAM Peptidase family M20 M25 M40 K01439 - 3.5.1.18 0.00000000000000000008021 96.0
HFD3_k127_4178784_9 histidine kinase A domain protein - - - 0.000000000000007746 82.0
HFD3_k127_4203675_0 Imidazolonepropionase and related - - - 1.389e-214 679.0
HFD3_k127_4203675_1 Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003383 531.0
HFD3_k127_4203675_10 NUDIX domain - - - 0.00000000000000000000000000000009286 144.0
HFD3_k127_4203675_11 efflux transmembrane transporter activity - - - 0.000000000000000000000000000004978 139.0
HFD3_k127_4203675_12 PAP2 superfamily - - - 0.0000000000000000000005664 109.0
HFD3_k127_4203675_2 C-terminal domain of 1-Cys peroxiredoxin K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 396.0
HFD3_k127_4203675_3 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009302 378.0
HFD3_k127_4203675_4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007424 341.0
HFD3_k127_4203675_5 ATPase activity K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 299.0
HFD3_k127_4203675_6 Serine aminopeptidase, S33 K06889 - - 0.0000000000000000000000000000000000000000000673 171.0
HFD3_k127_4203675_7 translation initiation factor activity K06996 - - 0.0000000000000000000000000000000000000000001992 162.0
HFD3_k127_4203675_8 HAD-hyrolase-like K01091 - 3.1.3.18 0.000000000000000000000000000000000000004466 158.0
HFD3_k127_4203675_9 - - - - 0.0000000000000000000000000000000000225 139.0
HFD3_k127_4223864_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 3.277e-240 772.0
HFD3_k127_4223864_1 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 432.0
HFD3_k127_4223864_2 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002162 305.0
HFD3_k127_4223864_3 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 302.0
HFD3_k127_4223864_4 DHH family K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000001494 237.0
HFD3_k127_4223864_5 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000007075 232.0
HFD3_k127_4223864_6 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000001503 138.0
HFD3_k127_4223864_7 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000008835 133.0
HFD3_k127_4223864_8 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000001055 113.0
HFD3_k127_4237148_0 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 556.0
HFD3_k127_4237148_1 FCD - - - 0.000001225 51.0
HFD3_k127_4273248_0 Glycosyl Hydrolase Family 88 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 599.0
HFD3_k127_4273248_1 PFAM Glycoside hydrolase, family 42 K12308 - 3.2.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004342 306.0
HFD3_k127_4273248_2 PFAM Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000346 273.0
HFD3_k127_4273248_3 and related - - - 0.0000000000000000000000000000000000000000000000000000000000000001403 238.0
HFD3_k127_4273248_4 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000001726 222.0
HFD3_k127_4280802_0 MacB-like periplasmic core domain - - - 2.614e-304 957.0
HFD3_k127_4280802_1 TIGRFAM Glyceraldehyde-3-phosphate dehydrogenase, type II K00150 - 1.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003724 544.0
HFD3_k127_4280802_10 alpha/beta hydrolase fold K01561 - 3.8.1.3 0.0000000001396 72.0
HFD3_k127_4280802_11 TonB dependent receptor - - - 0.000000001509 59.0
HFD3_k127_4280802_12 PFAM Sulfate transporter antisigma-factor antagonist STAS - - - 0.00000004992 58.0
HFD3_k127_4280802_13 ubiE/COQ5 methyltransferase family - - - 0.000002366 57.0
HFD3_k127_4280802_14 PA14 - - - 0.00008932 57.0
HFD3_k127_4280802_2 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 506.0
HFD3_k127_4280802_3 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000001045 197.0
HFD3_k127_4280802_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000002101 194.0
HFD3_k127_4280802_5 - - - - 0.00000000000000000000000000000000000000000000000368 194.0
HFD3_k127_4280802_6 COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily K01002 - 2.7.8.20 0.0000000000000000000000000000000366 147.0
HFD3_k127_4280802_7 domain protein K12516 - - 0.000000000000000000000000000001082 132.0
HFD3_k127_4280802_8 chaperone-mediated protein folding - - - 0.0000000000000000000000001015 124.0
HFD3_k127_4280802_9 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.00000000000000000002136 103.0
HFD3_k127_4281688_0 Sodium:solute symporter family K14393 - - 2.764e-233 737.0
HFD3_k127_4281688_1 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000718 288.0
HFD3_k127_4281688_2 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.0000000000000000000000000000000000000000000008991 176.0
HFD3_k127_4281688_3 Protein of unknown function, DUF485 - - - 0.000000000000000000000000000008369 121.0
HFD3_k127_42903_0 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000001039 214.0
HFD3_k127_42903_1 Putative glutamine amidotransferase - - - 0.0000000000000000000000000000000000000000000000000261 197.0
HFD3_k127_42903_2 Peptidase C14 caspase catalytic subunit p20 - - - 0.0000000000000000000000000000000002152 147.0
HFD3_k127_42903_3 Protein of unknown function (DUF2911) - - - 0.00000000000000000000000001827 116.0
HFD3_k127_42903_4 PFAM Rhomboid family K07059 - - 0.0009645 43.0
HFD3_k127_4305470_0 membrane protein involved in D-alanine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 490.0
HFD3_k127_4305470_1 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006552 427.0
HFD3_k127_4305470_2 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 358.0
HFD3_k127_4305470_3 PFAM glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007483 332.0
HFD3_k127_4305470_4 aromatic amino acid beta-eliminating lyase threonine aldolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002888 322.0
HFD3_k127_4305470_5 Pfam Glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000002786 245.0
HFD3_k127_4305470_6 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000002347 169.0
HFD3_k127_4305470_7 PFAM Tetratricopeptide TPR_4 - - - 0.000000000001297 78.0
HFD3_k127_4305470_8 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000009411 76.0
HFD3_k127_4305470_9 oligosaccharyl transferase activity - - - 0.000043 57.0
HFD3_k127_4328912_0 TIGRFAM ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter K01537 - 3.6.3.8 1.43e-237 746.0
HFD3_k127_4328912_1 lipolytic protein G-D-S-L family - - - 6.754e-216 696.0
HFD3_k127_4328912_10 peptidase S9 K01278 - 3.4.14.5 0.000000000004229 80.0
HFD3_k127_4328912_2 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 591.0
HFD3_k127_4328912_3 PFAM ATPase associated with various cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007899 444.0
HFD3_k127_4328912_4 NADP Oxidoreductase K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 353.0
HFD3_k127_4328912_5 Putative metallopeptidase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005691 319.0
HFD3_k127_4328912_6 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002701 258.0
HFD3_k127_4328912_7 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000006836 197.0
HFD3_k127_4328912_8 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000009222 182.0
HFD3_k127_4342569_0 Putative glutamine amidotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 474.0
HFD3_k127_4342569_1 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005421 438.0
HFD3_k127_4342569_2 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007756 259.0
HFD3_k127_4342569_3 Peptidase C14 caspase catalytic subunit p20 - - - 0.00000000000000000000000000000000000000000008192 175.0
HFD3_k127_4342569_4 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000004102 160.0
HFD3_k127_4342569_5 Putative glutamine amidotransferase - - - 0.000000000000000000000000000000000002061 144.0
HFD3_k127_4351132_0 Fg-gap repeat K18197 - 4.2.2.23 2.318e-244 797.0
HFD3_k127_4351132_1 Peptidase S46 - - - 1.372e-197 637.0
HFD3_k127_4351132_10 DinB family - - - 0.0000000000000000000000000000000000000000001873 165.0
HFD3_k127_4351132_11 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000006768 158.0
HFD3_k127_4351132_12 Thiamine-binding protein - - - 0.00000000000000000000000000000000002625 144.0
HFD3_k127_4351132_13 Nitrous oxide-stimulated promoter - - - 0.00000000000000000000000000000000008727 136.0
HFD3_k127_4351132_14 - - - - 0.000000000000000000000000000000003278 137.0
HFD3_k127_4351132_15 Nucleoside-diphosphate-sugar epimerases - - - 0.000000000000000000000003924 104.0
HFD3_k127_4351132_16 helix_turn_helix, mercury resistance - - - 0.0000000000000000005499 91.0
HFD3_k127_4351132_17 COG0656 Aldo keto reductases, related to diketogulonate reductase - - - 0.000000005574 58.0
HFD3_k127_4351132_2 Pectate lyase superfamily protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005853 569.0
HFD3_k127_4351132_3 Glycogen debranching enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005215 550.0
HFD3_k127_4351132_4 Pirin C-terminal cupin domain K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005996 486.0
HFD3_k127_4351132_5 von Willebrand factor type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 435.0
HFD3_k127_4351132_6 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 388.0
HFD3_k127_4351132_7 Amino acid kinase family K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 361.0
HFD3_k127_4351132_8 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009381 364.0
HFD3_k127_4351132_9 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000003329 273.0
HFD3_k127_4354590_0 Deoxyhypusine synthase K00809 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 351.0
HFD3_k127_4354590_1 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005735 342.0
HFD3_k127_4354590_2 Belongs to the arginase family K01476,K01480 - 3.5.3.1,3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000002226 259.0
HFD3_k127_4354590_3 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000001473 213.0
HFD3_k127_4354590_4 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin K00365 - 1.7.3.3 0.00000000000000000000000000000000003469 146.0
HFD3_k127_4354590_5 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.0000000000000000007227 89.0
HFD3_k127_4354590_6 PFAM WD40 domain protein beta Propeller - - - 0.000000000000000000852 94.0
HFD3_k127_4354590_7 Tetratricopeptide repeat - - - 0.0000000003126 70.0
HFD3_k127_4354590_8 - - - - 0.0004054 48.0
HFD3_k127_4389114_0 cellulose binding - - - 8.2e-268 852.0
HFD3_k127_4389114_1 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 479.0
HFD3_k127_4389114_2 Glutamine cyclotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 312.0
HFD3_k127_4389114_3 GtrA-like protein - - - 0.000000000000000000000000006653 121.0
HFD3_k127_4389114_4 YjbR - - - 0.00000000000000000000000363 106.0
HFD3_k127_4389114_5 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000000000000000004278 98.0
HFD3_k127_4389114_8 - - - - 0.00000000004876 73.0
HFD3_k127_4397761_0 serine-type peptidase activity - - - 0.0 1105.0
HFD3_k127_4397761_1 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 620.0
HFD3_k127_4397761_10 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000008072 163.0
HFD3_k127_4397761_11 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000000000292 156.0
HFD3_k127_4397761_13 efflux transmembrane transporter activity - - - 0.00000000000000000000001768 110.0
HFD3_k127_4397761_14 FtsX-like permease family - - - 0.00000000000000000008395 101.0
HFD3_k127_4397761_15 - - - - 0.000000000000003342 76.0
HFD3_k127_4397761_16 MacB-like periplasmic core domain - - - 0.00000000000000449 80.0
HFD3_k127_4397761_17 PIN domain - - - 0.0000000000002137 77.0
HFD3_k127_4397761_18 - - - - 0.000000000001737 74.0
HFD3_k127_4397761_19 ECF sigma factor K03088 - - 0.000000001313 68.0
HFD3_k127_4397761_2 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006195 613.0
HFD3_k127_4397761_3 Amino acid kinase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 535.0
HFD3_k127_4397761_4 oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 488.0
HFD3_k127_4397761_5 Flotillin K07192 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000456 406.0
HFD3_k127_4397761_6 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003269 369.0
HFD3_k127_4397761_7 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 332.0
HFD3_k127_4397761_8 DinB family - - - 0.000000000000000000000000000000000000000000000000001336 187.0
HFD3_k127_4397761_9 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000222 184.0
HFD3_k127_4411570_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008983 485.0
HFD3_k127_4411570_1 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 471.0
HFD3_k127_4411570_2 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 308.0
HFD3_k127_4411570_3 Pyridoxal phosphate biosynthetic protein PdxA K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.0000000000000000000000000000000000000000000000000000000000000000000000000001131 266.0
HFD3_k127_4411570_4 Fad dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000004843 247.0
HFD3_k127_4411570_5 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564 - 0.0000000000000000000000000000000000000000000000000005036 188.0
HFD3_k127_4411570_6 -O-antigen - - - 0.00000001314 68.0
HFD3_k127_4418765_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 7.182e-282 906.0
HFD3_k127_4418765_1 LytB protein K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000522 455.0
HFD3_k127_4418765_10 Heavy-metal resistance - - - 0.0001533 51.0
HFD3_k127_4418765_2 response regulator K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 383.0
HFD3_k127_4418765_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007438 286.0
HFD3_k127_4418765_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000007083 180.0
HFD3_k127_4418765_5 outer membrane efflux protein - - - 0.000000000000000000000000000000000000000002336 175.0
HFD3_k127_4418765_6 SpoIID LytB domain protein K06381 - - 0.0000000000000000000000000000002794 135.0
HFD3_k127_4418765_7 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000002662 111.0
HFD3_k127_4418765_8 Sigma-54 interaction domain K10126 - - 0.0000002351 63.0
HFD3_k127_4418765_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00009917 55.0
HFD3_k127_4423609_0 MacB-like periplasmic core domain - - - 0.0 1062.0
HFD3_k127_4423609_1 sigma factor activity K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006958 390.0
HFD3_k127_4423609_10 Protein of unknown function (DUF4199) - - - 0.0000001587 55.0
HFD3_k127_4423609_2 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006788 314.0
HFD3_k127_4423609_3 Doubled CXXCH motif (Paired_CXXCH_1) K08354 - - 0.0000000000000000000000000000000000000000000000000000000000000000000369 243.0
HFD3_k127_4423609_4 PFAM Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000004586 190.0
HFD3_k127_4423609_5 Protein of unknown function (DUF1428) - - - 0.0000000000000000000000000000000000000000000003716 180.0
HFD3_k127_4423609_7 Putative outer membrane beta-barrel porin, MtrB/PioB K22110 - - 0.00000000000000000000000000000002278 146.0
HFD3_k127_4423609_8 methyltransferase - - - 0.00000000000000000000000002479 116.0
HFD3_k127_4423609_9 Cytochrome c K00413 - - 0.00000000002854 73.0
HFD3_k127_4425634_0 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 9.35e-229 717.0
HFD3_k127_4425634_1 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 436.0
HFD3_k127_4425634_10 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000003525 138.0
HFD3_k127_4425634_11 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.000000000000000000000000004047 117.0
HFD3_k127_4425634_12 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.000000000000001083 91.0
HFD3_k127_4425634_13 - K01992 - - 0.00000001934 63.0
HFD3_k127_4425634_14 Belongs to the peptidase S8 family - - - 0.00012 54.0
HFD3_k127_4425634_2 Dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000364 395.0
HFD3_k127_4425634_3 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002231 391.0
HFD3_k127_4425634_4 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 380.0
HFD3_k127_4425634_5 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 338.0
HFD3_k127_4425634_6 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000391 321.0
HFD3_k127_4425634_7 gtp cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000002477 264.0
HFD3_k127_4425634_8 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000001402 247.0
HFD3_k127_4425634_9 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000002789 151.0
HFD3_k127_4426314_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003723 514.0
HFD3_k127_4426314_1 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006141 409.0
HFD3_k127_4426314_2 PFAM 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006506 356.0
HFD3_k127_4426314_3 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006757 286.0
HFD3_k127_4426314_4 COG1555 DNA uptake protein and related DNA-binding proteins - - - 0.00000000000000000000000000005803 134.0
HFD3_k127_4426314_5 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000362 105.0
HFD3_k127_4426314_6 membrane-bound metal-dependent K07038 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000643 74.0
HFD3_k127_4426314_7 - - - - 0.0007747 43.0
HFD3_k127_4467517_0 peptidyl-tyrosine sulfation K01277 - 3.4.14.4 3.034e-292 915.0
HFD3_k127_4467517_1 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 488.0
HFD3_k127_4467517_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002095 291.0
HFD3_k127_4467517_3 Aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000002945 286.0
HFD3_k127_4467517_4 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000099 278.0
HFD3_k127_4467517_5 Short-chain dehydrogenase reductase SDR K03793 - 1.5.1.33 0.0000000000000000000000000000000000000000002211 168.0
HFD3_k127_4467517_6 PFAM transcriptional regulator domain protein - - - 0.00000000000000000000000003261 115.0
HFD3_k127_4469758_0 AAA ATPase domain K12132 - 2.7.11.1 7.016e-194 647.0
HFD3_k127_4469758_1 IgA Peptidase M64 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007514 526.0
HFD3_k127_4469758_10 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000000000000000000000000000000000000000004963 247.0
HFD3_k127_4469758_11 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000003047 224.0
HFD3_k127_4469758_12 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000006777 218.0
HFD3_k127_4469758_13 ApaG domain K06195 - - 0.00000000000000000000000000000000000000000000001712 179.0
HFD3_k127_4469758_14 YceI-like domain - - - 0.0000000000000000000000000000000000000000002794 168.0
HFD3_k127_4469758_15 Cytochrome c - - - 0.0000000000000000000000000000000000006799 150.0
HFD3_k127_4469758_16 TonB-dependent receptor K02014 - - 0.0000000000000000000000000000004042 138.0
HFD3_k127_4469758_17 Membrane - - - 0.0000000000000000000000000001913 127.0
HFD3_k127_4469758_18 Cytochrome c K08685 - 1.4.9.1 0.00000000000000000000000006134 110.0
HFD3_k127_4469758_19 Male sterility protein K15891 - 1.1.1.354 0.000000000000002233 80.0
HFD3_k127_4469758_2 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 508.0
HFD3_k127_4469758_20 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000007617 89.0
HFD3_k127_4469758_21 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0001588 51.0
HFD3_k127_4469758_3 Uncharacterized protein conserved in bacteria (DUF2264) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004893 467.0
HFD3_k127_4469758_4 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 459.0
HFD3_k127_4469758_5 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 448.0
HFD3_k127_4469758_6 Cytochrome c K08685 - 1.4.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007289 347.0
HFD3_k127_4469758_7 Integral membrane protein TerC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 323.0
HFD3_k127_4469758_8 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007407 255.0
HFD3_k127_4469758_9 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000002551 263.0
HFD3_k127_4484353_0 Belongs to the glycosyl hydrolase 2 family K01190 - 3.2.1.23 0.0 1035.0
HFD3_k127_4484353_1 MacB-like periplasmic core domain - - - 2.507e-292 921.0
HFD3_k127_4484353_10 Periplasmic binding protein domain K10439 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 350.0
HFD3_k127_4484353_11 Inosine-uridine preferring nucleoside hydrolase K01250 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004585 360.0
HFD3_k127_4484353_12 Belongs to the binding-protein-dependent transport system permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006592 340.0
HFD3_k127_4484353_13 Phosphomethylpyrimidine kinase K00852 GO:0003674,GO:0003824,GO:0004747,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019303,GO:0019321,GO:0019323,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046835,GO:0071704,GO:1901575 2.7.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007095 309.0
HFD3_k127_4484353_14 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009109 295.0
HFD3_k127_4484353_15 ABC-type sugar transport system periplasmic component K02058,K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001985 287.0
HFD3_k127_4484353_16 PAP2 superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000008161 253.0
HFD3_k127_4484353_17 Peptidylprolyl isomerase K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000366 217.0
HFD3_k127_4484353_18 Acetyltransferase (GNAT) domain K03827 - - 0.00000000000000000000000000000000000000000000000003216 184.0
HFD3_k127_4484353_19 - - - - 0.0000000000000000000000000000000000000000000000004488 198.0
HFD3_k127_4484353_2 amine dehydrogenase activity K17285 - - 1.959e-229 718.0
HFD3_k127_4484353_20 ECF sigma factor - - - 0.000000000000000000000000000000000000000000001898 181.0
HFD3_k127_4484353_21 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000000000001209 156.0
HFD3_k127_4484353_22 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000004457 132.0
HFD3_k127_4484353_23 Aldolase/RraA - - - 0.00000000000000000000000000005475 128.0
HFD3_k127_4484353_25 DoxX-like family - - - 0.0000000000000000002735 94.0
HFD3_k127_4484353_26 phosphorelay signal transduction system K07713,K07714,K10943 - - 0.000000000003972 76.0
HFD3_k127_4484353_27 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K10941 - - 0.00000000007111 70.0
HFD3_k127_4484353_28 OsmC-like protein - - - 0.000009414 53.0
HFD3_k127_4484353_3 Carbohydrate family 9 binding domain-like - - - 2.995e-196 644.0
HFD3_k127_4484353_4 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 564.0
HFD3_k127_4484353_5 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006038 534.0
HFD3_k127_4484353_6 ABC transporter K10441 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007328 501.0
HFD3_k127_4484353_7 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 451.0
HFD3_k127_4484353_8 2-epimerase K16213 - 5.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003295 392.0
HFD3_k127_4484353_9 Transcriptional regulator K03717 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 351.0
HFD3_k127_4486030_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 0.0 1211.0
HFD3_k127_4486030_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 420.0
HFD3_k127_4486030_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000002375 222.0
HFD3_k127_4486030_3 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000000004234 124.0
HFD3_k127_4486030_4 protocatechuate 3,4-dioxygenase activity K00449 - 1.13.11.3 0.000000000000000000000000000006211 124.0
HFD3_k127_4496293_0 - - - - 1.122e-274 859.0
HFD3_k127_4496293_1 efflux transmembrane transporter activity - - - 1.124e-265 849.0
HFD3_k127_4496293_2 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 374.0
HFD3_k127_4496293_3 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 333.0
HFD3_k127_4496293_4 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000002507 163.0
HFD3_k127_4496293_5 - - - - 0.0000000004918 69.0
HFD3_k127_4514349_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000004896 169.0
HFD3_k127_4514349_1 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000000000002968 168.0
HFD3_k127_4527912_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01706 - 4.2.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 595.0
HFD3_k127_4527912_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008885 496.0
HFD3_k127_4527912_2 histidine kinase dimerisation and phosphoacceptor region K11617 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003299 370.0
HFD3_k127_4527912_3 Dihydrodipicolinate synthetase family K01707 - 4.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000002575 272.0
HFD3_k127_4527912_4 PFAM regulatory protein LuxR K02479 - - 0.00000000000000000000000000000000000000000000000000000005014 222.0
HFD3_k127_4527912_5 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000009121 110.0
HFD3_k127_4527912_6 23S rRNA-intervening sequence protein - - - 0.00000000001759 74.0
HFD3_k127_4563000_0 Trehalose utilisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 332.0
HFD3_k127_4563000_1 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000001714 174.0
HFD3_k127_4563000_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000001968 147.0
HFD3_k127_4581585_0 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 339.0
HFD3_k127_4581861_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005262 365.0
HFD3_k127_4581861_1 FCD K05799 - - 0.0000000000000000000000000000000000000000000000000000000000000929 222.0
HFD3_k127_4581861_2 tagaturonate epimerase - - - 0.0000000000000000001819 89.0
HFD3_k127_469652_0 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004328 559.0
HFD3_k127_469652_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 440.0
HFD3_k127_469652_10 PFAM response regulator receiver K02483,K07658,K07668 - - 0.00000000000000000000000000000000000000000000000000001228 197.0
HFD3_k127_469652_11 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000000002135 189.0
HFD3_k127_469652_12 VIT family - - - 0.00000000000000000000000000000000000000000000000001397 184.0
HFD3_k127_469652_13 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104,K03325,K03741,K03892,K18701 - 1.20.4.1,2.8.4.2,3.1.3.48 0.00000000000000000000000000000000000000000000000001623 183.0
HFD3_k127_469652_14 PFAM Phosphate-selective porin O and P - - - 0.000000000000000000000000000000002165 146.0
HFD3_k127_469652_15 PFAM regulatory protein ArsR K03892 - - 0.00000000000000000000006097 106.0
HFD3_k127_469652_16 Belongs to the NiCoT transporter (TC 2.A.52) family - - - 0.00000000001244 76.0
HFD3_k127_469652_17 Protein of unknown function (DUF3891) - - - 0.00000009167 63.0
HFD3_k127_469652_18 Protein of unknown function (DUF433) - - - 0.0000001042 59.0
HFD3_k127_469652_19 SMART cyclic nucleotide-binding - - - 0.0001884 47.0
HFD3_k127_469652_2 PFAM phosphate transporter K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 415.0
HFD3_k127_469652_20 - - - - 0.0002281 47.0
HFD3_k127_469652_3 Hypothetical methyltransferase K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 389.0
HFD3_k127_469652_4 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009918 367.0
HFD3_k127_469652_5 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 363.0
HFD3_k127_469652_6 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 358.0
HFD3_k127_469652_7 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 331.0
HFD3_k127_469652_8 Phosphate sensor histidine kinase, HAMP and PAS domain-containing K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 345.0
HFD3_k127_469652_9 Transcriptional regulatory protein, C terminal K07658 - - 0.0000000000000000000000000000000000000000000000000000000000000000004917 241.0
HFD3_k127_4701853_0 PFAM Uncharacterised BCR, COG1649 - - - 1.425e-281 880.0
HFD3_k127_4701853_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 1.27e-213 672.0
HFD3_k127_4701853_2 Protein of unknown function (DUF4038) - - - 3.404e-207 676.0
HFD3_k127_4701853_3 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 419.0
HFD3_k127_4701853_4 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 379.0
HFD3_k127_4701853_5 PFAM Uncharacterised BCR, COG1649 - - - 0.0000000000000000000000000000000000004872 143.0
HFD3_k127_4708533_0 Penicillin amidase K07116 - 3.5.1.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 439.0
HFD3_k127_4708533_1 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000003087 229.0
HFD3_k127_4708533_2 PFAM SpoU rRNA Methylase family - - - 0.0000000000000000000000000000000000000000000000000000003592 203.0
HFD3_k127_4708533_3 2OG-Fe(II) oxygenase superfamily - - - 0.000000000000000000000000000000000000000000000009436 178.0
HFD3_k127_4708533_4 Metallopeptidase family M24 K01265 - 3.4.11.18 0.0000000000000000000000000005813 115.0
HFD3_k127_4708533_5 PFAM Helix-turn-helix K07729 - - 0.0000000000000005769 79.0
HFD3_k127_4708533_7 Putative regulatory protein - - - 0.0000003328 58.0
HFD3_k127_4708533_8 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00003558 54.0
HFD3_k127_4708533_9 DinB superfamily - - - 0.0001461 47.0
HFD3_k127_4729613_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain - - - 7.862e-259 812.0
HFD3_k127_4729613_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 557.0
HFD3_k127_4729613_2 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006532 428.0
HFD3_k127_4729613_3 geranylgeranyl reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007036 402.0
HFD3_k127_4729613_4 von Willebrand factor, type A K07114 - - 0.00000000000000000000000001171 119.0
HFD3_k127_4729613_5 - - - - 0.000000000000000000004484 100.0
HFD3_k127_4729613_6 TIGRFAM MoaD family protein K03636 - - 0.0000000007539 64.0
HFD3_k127_4748736_0 ABC1 family K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 571.0
HFD3_k127_4748736_1 ROK family K00847 - 2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000838 409.0
HFD3_k127_4748736_2 peroxidase activity K00435 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006649 271.0
HFD3_k127_4748736_3 HAD-hyrolase-like K07025 - - 0.000000000000000000000000000000000000000000000001868 183.0
HFD3_k127_4748736_4 general stress protein - - - 0.0000000004208 64.0
HFD3_k127_4771055_0 COG1070 Sugar (pentulose and hexulose) K00848 - 2.7.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006698 449.0
HFD3_k127_4771055_1 pyrroloquinoline quinone binding K01206 - 3.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004557 278.0
HFD3_k127_4771055_2 Helix-hairpin-helix motif K02237 - - 0.000000000000000000000000003475 116.0
HFD3_k127_4771055_3 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000009496 72.0
HFD3_k127_4771412_0 COGs COG0531 Amino acid transporter K03294,K20265 - - 0.000000000000000000000000000000000000000000000000009776 191.0
HFD3_k127_4771412_1 - - - - 0.0001299 53.0
HFD3_k127_4786543_0 lipopolysaccharide transport K22110 - - 0.0 1387.0
HFD3_k127_4786543_1 TonB-dependent Receptor Plug Domain - - - 0.0 1044.0
HFD3_k127_4786543_10 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003772 385.0
HFD3_k127_4786543_11 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 332.0
HFD3_k127_4786543_12 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001212 257.0
HFD3_k127_4786543_13 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.00000000000000000000000000000000000000000000000000000000000000000007213 240.0
HFD3_k127_4786543_14 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000002771 236.0
HFD3_k127_4786543_15 O-methyltransferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000005485 240.0
HFD3_k127_4786543_16 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000009865 239.0
HFD3_k127_4786543_17 Cellulose biosynthesis protein BcsQ K03496 - - 0.000000000000000000000000000000000000001019 159.0
HFD3_k127_4786543_18 - - - - 0.0000000000000000000000000000000000005347 144.0
HFD3_k127_4786543_19 Transport and Golgi organisation 2 - - - 0.000000000000000000000000000000000002803 153.0
HFD3_k127_4786543_2 choline dehydrogenase activity - - - 8.823e-255 807.0
HFD3_k127_4786543_20 DinB family - - - 0.000000000000000000000219 109.0
HFD3_k127_4786543_21 Ferredoxin - - - 0.00000000000000000004354 104.0
HFD3_k127_4786543_22 Dodecin - - - 0.0000000000000000001814 92.0
HFD3_k127_4786543_23 Cytochrome c - - - 0.0000000000000002606 86.0
HFD3_k127_4786543_24 His Kinase A (phosphoacceptor) domain - - - 0.000000000000001215 83.0
HFD3_k127_4786543_25 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000005748 80.0
HFD3_k127_4786543_26 PEGA domain K15539 - - 0.0000004766 61.0
HFD3_k127_4786543_3 Amylo-alpha-1,6-glucosidase - - - 1.904e-238 754.0
HFD3_k127_4786543_4 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 522.0
HFD3_k127_4786543_5 alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009759 482.0
HFD3_k127_4786543_6 PFAM Tannase and feruloyl esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004871 483.0
HFD3_k127_4786543_7 Transport and Golgi organisation 2 K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 461.0
HFD3_k127_4786543_8 SMART Phospholipid glycerol acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 415.0
HFD3_k127_4786543_9 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 388.0
HFD3_k127_4788437_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 534.0
HFD3_k127_4788437_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009508 501.0
HFD3_k127_4788437_10 Tetratricopeptide repeats - - - 0.00000000000000002017 97.0
HFD3_k127_4788437_11 Belongs to the UPF0109 family K06960 - - 0.0000000000009782 75.0
HFD3_k127_4788437_12 - - - - 0.000004646 60.0
HFD3_k127_4788437_13 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00001253 56.0
HFD3_k127_4788437_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 312.0
HFD3_k127_4788437_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004203 296.0
HFD3_k127_4788437_4 tRNA (Guanine-1)-methyltransferase K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005082 282.0
HFD3_k127_4788437_5 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000005305 184.0
HFD3_k127_4788437_6 riboflavin synthase, alpha K00793 - 2.5.1.9 0.000000000000000000000000000000000000001826 154.0
HFD3_k127_4788437_7 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000011 144.0
HFD3_k127_4788437_8 RimM N-terminal domain K02860 GO:0008150,GO:0040007 - 0.000000000000000000000004701 113.0
HFD3_k127_4788437_9 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000006486 95.0
HFD3_k127_4844290_0 MacB-like periplasmic core domain - - - 2.133e-298 940.0
HFD3_k127_4844290_1 Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 406.0
HFD3_k127_4844290_2 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane K02761 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006752 355.0
HFD3_k127_4844290_3 aromatic amino acid beta-eliminating lyase threonine aldolase - - - 0.000000000000000000000000000003197 125.0
HFD3_k127_484532_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 3.084e-300 945.0
HFD3_k127_484532_1 Sodium/hydrogen exchanger family K03455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 596.0
HFD3_k127_484532_11 Domain of unknown function (DUF3520) K07114 - - 0.0005123 43.0
HFD3_k127_484532_2 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000916 391.0
HFD3_k127_484532_3 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004357 380.0
HFD3_k127_484532_4 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004902 265.0
HFD3_k127_484532_5 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001424 260.0
HFD3_k127_484532_6 NIPSNAP - - - 0.00000000000000000000000000000000000000000000000000000000003271 217.0
HFD3_k127_484532_7 Yip1 domain - - - 0.00000000000000000000000000000000000000000001835 170.0
HFD3_k127_484532_8 chain release factor K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.0000000000000000000000000000000000002953 144.0
HFD3_k127_484532_9 PhoPQ-activated pathogenicity-related protein - - - 0.0000000003326 62.0
HFD3_k127_4848903_0 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001226 285.0
HFD3_k127_4848903_1 FMN-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000005556 250.0
HFD3_k127_4848903_2 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000002721 211.0
HFD3_k127_4848903_3 - K03616 - - 0.0000000000000000000000000000004648 132.0
HFD3_k127_4848903_4 Protein of unknown function (DUF1622) - - - 0.00000000000000000000000000000692 122.0
HFD3_k127_4848903_5 amine dehydrogenase activity - - - 0.000000000000000000000003444 113.0
HFD3_k127_4848903_6 TIGRFAM redox-active disulfide protein 1 - - - 0.0000001975 59.0
HFD3_k127_4860223_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1150.0
HFD3_k127_4860223_1 amino acid K03294 - - 1.761e-206 654.0
HFD3_k127_4860223_10 NADP transhydrogenase K00324 - 1.6.1.2 0.0000000000000000000009722 98.0
HFD3_k127_4860223_2 transmembrane transporter activity K08191 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005806 567.0
HFD3_k127_4860223_3 NAD(P) transhydrogenase beta subunit K00325 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005708 551.0
HFD3_k127_4860223_4 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K11102 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 478.0
HFD3_k127_4860223_5 Citrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000468 433.0
HFD3_k127_4860223_6 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004025 323.0
HFD3_k127_4860223_7 Ion channel K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000472 293.0
HFD3_k127_4860223_8 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.00000000000000000000000000000000000000000009004 175.0
HFD3_k127_4860223_9 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.00000000000000000000000000000000000000006506 158.0
HFD3_k127_4888570_0 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 301.0
HFD3_k127_4888570_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008371 293.0
HFD3_k127_4888570_2 Cytidine and deoxycytidylate deaminase zinc-binding region K01489 - 3.5.4.5 0.00000000000000000000000000000000000000004742 162.0
HFD3_k127_4921680_0 PQQ-like domain K00114 - 1.1.2.8 4.166e-243 760.0
HFD3_k127_4921680_1 COG0577 ABC-type antimicrobial peptide transport system permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 528.0
HFD3_k127_4921680_10 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000006064 201.0
HFD3_k127_4921680_11 Protein of unknown function (DUF1211) - GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016043,GO:0022607,GO:0022803,GO:0022838,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0043933,GO:0044085,GO:0046873,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055085,GO:0065003,GO:0071804,GO:0071805,GO:0071840,GO:0098655,GO:0098660,GO:0098662 - 0.000000000000000000000000000000000000000000001028 174.0
HFD3_k127_4921680_12 Ferredoxin - - - 0.00000000000000000000000000000008493 137.0
HFD3_k127_4921680_13 Outer membrane protein beta-barrel family K16087,K16092 - - 0.0000000000000000000000000000009748 141.0
HFD3_k127_4921680_14 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000008926 104.0
HFD3_k127_4921680_15 Putative regulatory protein - - - 0.000000009354 59.0
HFD3_k127_4921680_2 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004871 473.0
HFD3_k127_4921680_3 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 453.0
HFD3_k127_4921680_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 437.0
HFD3_k127_4921680_5 DNA ligase K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 415.0
HFD3_k127_4921680_6 beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004653 405.0
HFD3_k127_4921680_7 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003648 282.0
HFD3_k127_4921680_8 acyl-CoA dehydrogenase activity K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000002278 215.0
HFD3_k127_4921680_9 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000002016 198.0
HFD3_k127_4934824_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1125.0
HFD3_k127_4934824_1 COG1680 Beta-lactamase class C and other penicillin binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 461.0
HFD3_k127_4934824_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 442.0
HFD3_k127_4934824_3 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002652 306.0
HFD3_k127_4934824_4 Glycosyltransferase like family 2 K10012,K20534 - 2.4.2.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005153 289.0
HFD3_k127_4934824_5 TIR domain - - - 0.0000000000000000000000000000000000000000000002117 186.0
HFD3_k127_4934824_6 - - - - 0.0000000000001543 76.0
HFD3_k127_4950420_0 nuclear chromosome segregation - - - 0.0000000002533 72.0
HFD3_k127_4971341_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1157.0
HFD3_k127_4971341_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 7.584e-219 698.0
HFD3_k127_4971341_2 symporter activity K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007404 361.0
HFD3_k127_4971341_3 DnaJ molecular chaperone homology domain K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 326.0
HFD3_k127_4971341_4 Peptidase M14, carboxypeptidase A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003356 293.0
HFD3_k127_4971341_5 COG0861 Membrane protein TerC, possibly involved in tellurium resistance - - - 0.00000000000000000000000000000000000000000001275 171.0
HFD3_k127_4971341_6 domain protein K14194 - - 0.0000000000000000000000000000000000000000001262 180.0
HFD3_k127_4971341_7 helix_turn_helix, mercury resistance K13640 - - 0.000000000000000000000001728 108.0
HFD3_k127_5011893_0 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007401 291.0
HFD3_k127_5011893_1 Tetratricopeptide repeat - - - 0.0000000000685 72.0
HFD3_k127_5022797_0 Fumarate hydratase (Fumerase) K01676 - 4.2.1.2 2.041e-219 713.0
HFD3_k127_5022797_1 Aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005803 528.0
HFD3_k127_5022797_2 Fumarase C C-terminus K01744 - 4.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005233 499.0
HFD3_k127_5022797_3 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000007443 269.0
HFD3_k127_5022797_4 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000001045 233.0
HFD3_k127_5022797_5 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.0000000000000000000000000000000000000000000000000002315 192.0
HFD3_k127_5022797_6 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.0000000000000000000000000000000000002547 150.0
HFD3_k127_5022797_7 Required for insertion of 4Fe-4S clusters K15724 - - 0.00000000000000000000000000000000007634 136.0
HFD3_k127_5022797_8 Belongs to the Fur family K03711 - - 0.000000000000000000000000004781 119.0
HFD3_k127_5029032_0 Belongs to the peptidase M16 family K07263 - - 1.368e-197 658.0
HFD3_k127_5029032_1 beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 410.0
HFD3_k127_5029032_2 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 345.0
HFD3_k127_5029032_3 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000005992 167.0
HFD3_k127_5029032_4 MatE - - - 0.0000001536 53.0
HFD3_k127_5029297_0 Proline racemase K01777 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0018112,GO:0019752,GO:0036361,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0047661,GO:0071704,GO:1901564 5.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 336.0
HFD3_k127_5029297_1 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004756 290.0
HFD3_k127_5029297_2 Tetratricopeptide repeat - - - 0.000000000000000000003281 107.0
HFD3_k127_5042651_0 Sodium:solute symporter family - - - 3.136e-280 871.0
HFD3_k127_5042651_1 Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde K00656,K20038 - 2.3.1.54,4.3.99.4 1.974e-268 841.0
HFD3_k127_5042651_2 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007959 455.0
HFD3_k127_5042651_3 Belongs to the GHMP kinase family K00849 - 2.7.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 353.0
HFD3_k127_5042651_4 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 301.0
HFD3_k127_5042651_5 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000001018 228.0
HFD3_k127_5042651_6 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000000000000000004575 144.0
HFD3_k127_5042651_7 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000001657 102.0
HFD3_k127_5042651_8 - - - - 0.000000000000445 80.0
HFD3_k127_5057376_0 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003716 595.0
HFD3_k127_5057376_1 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 373.0
HFD3_k127_5057376_2 LytTr DNA-binding domain K02477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008173 296.0
HFD3_k127_5057376_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003442 256.0
HFD3_k127_5057376_4 Copper binding periplasmic protein CusF K07152 - - 0.000000000000000000000000000000000000000000000000001148 194.0
HFD3_k127_5057376_5 membrane - - - 0.00000000000000000000000000000000000000000000000007088 186.0
HFD3_k127_5057376_6 - - - - 0.00000000000000000000000000000000000000000001396 177.0
HFD3_k127_5057376_7 RNA recognition motif - - - 0.000000000000000000000000005719 114.0
HFD3_k127_5057376_8 transcriptional regulator - - - 0.00000000000000000000003688 107.0
HFD3_k127_5057376_9 - - - - 0.00000004912 64.0
HFD3_k127_5096994_0 PFAM carboxyl transferase K01969,K15052 - 2.1.3.15,6.4.1.3,6.4.1.4 5.435e-256 797.0
HFD3_k127_5096994_1 Carbamoyl-phosphate synthase L chain K01968,K11263 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003713 540.0
HFD3_k127_5096994_10 cheY-homologous receiver domain - - - 0.0000000000000000000000000001601 119.0
HFD3_k127_5096994_11 cheY-homologous receiver domain - - - 0.0000000000000000000001228 108.0
HFD3_k127_5096994_12 Lysin motif - - - 0.00000000000000000001762 102.0
HFD3_k127_5096994_13 glycoside hydrolase family 81 - - - 0.0000000002683 74.0
HFD3_k127_5096994_14 F5/8 type C domain - - - 0.000000395 61.0
HFD3_k127_5096994_2 COG2706 3-carboxymuconate cyclase K07404 - 3.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003864 394.0
HFD3_k127_5096994_3 L,D-transpeptidase catalytic domain K21470 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007059 373.0
HFD3_k127_5096994_4 HMGL-like K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004855 325.0
HFD3_k127_5096994_5 response regulator K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001659 281.0
HFD3_k127_5096994_6 Enoyl-CoA hydratase/isomerase K13766,K13779 - 4.2.1.18,4.2.1.57 0.00000000000000000000000000000000000000000000000000000000000000000000000004533 257.0
HFD3_k127_5096994_7 PHP domain K04477 - - 0.00000000000000000000000000000000000000000000000003604 194.0
HFD3_k127_5096994_8 Probably functions as a manganese efflux pump - - - 0.0000000000000000000000000000000000000000003854 179.0
HFD3_k127_5096994_9 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000002332 151.0
HFD3_k127_5111884_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 443.0
HFD3_k127_5111884_1 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008273 351.0
HFD3_k127_5111884_2 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 313.0
HFD3_k127_5111884_3 Diphthamide synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 286.0
HFD3_k127_5111884_4 TIGRFAM SUF system FeS K04488 - - 0.000000000000000000000000000000000000000000000000001487 196.0
HFD3_k127_5111884_5 Removes the phosphate from trehalose 6-phosphate to produce free trehalose - - - 0.0000000000000000000000000000000000000004534 164.0
HFD3_k127_5111884_6 Transcriptional regulator - - - 0.00000000000000000000000000000007476 129.0
HFD3_k127_5111884_7 PaaD-like protein - - - 0.000000000000000000000000000003962 131.0
HFD3_k127_5118642_0 PFAM glycoside hydrolase family 1 K05350 - 3.2.1.21 6.368e-227 712.0
HFD3_k127_5118642_1 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005327 389.0
HFD3_k127_5118642_2 TIGRFAM ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000003594 272.0
HFD3_k127_5118642_3 - - - - 0.000000000000000000000000000000000000000000003555 170.0
HFD3_k127_5118642_4 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000002416 164.0
HFD3_k127_5118642_5 Histidine kinase HAMP - - - 0.00000000000000000000000000000000000001025 166.0
HFD3_k127_5118642_6 Protein of unknown function (DUF1569) - - - 0.0000000000000000000000000000000000003887 145.0
HFD3_k127_5118642_7 DinB family - - - 0.0000000000335 73.0
HFD3_k127_5118642_8 RESPONSE REGULATOR receiver - - - 0.0001335 49.0
HFD3_k127_5135572_0 Glycogen debranching enzyme K05989 - 3.2.1.40 0.0 1210.0
HFD3_k127_5135572_1 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003621 579.0
HFD3_k127_5135572_2 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007602 452.0
HFD3_k127_5135572_3 BNR repeat-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 416.0
HFD3_k127_5135572_4 hemerythrin HHE cation binding domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000366 264.0
HFD3_k127_5135572_5 PFAM helix-turn-helix- domain containing protein, AraC type - - - 0.0000000000000000000000004153 111.0
HFD3_k127_5136031_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 496.0
HFD3_k127_5136031_1 Transglycosylase SLT domain K01185 - 3.2.1.17 0.000000000000000000000000000000000004679 146.0
HFD3_k127_5136031_2 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000003529 82.0
HFD3_k127_5136031_3 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit S4 paralog K04762 - - 0.0000000000002975 75.0
HFD3_k127_5136031_4 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.00000000001936 72.0
HFD3_k127_5231979_0 Oligopeptidase F K08602 - - 4.334e-208 668.0
HFD3_k127_5231979_1 hydrolase of the alpha beta-hydrolase fold K07020 - - 0.0000000000000000000000000000000000000001604 157.0
HFD3_k127_5231979_2 PFAM phospholipase Carboxylesterase - - - 0.000000000000000000000000001227 125.0
HFD3_k127_5231979_3 tetR family - - - 0.00000000379 66.0
HFD3_k127_524975_0 Dehydrogenase E1 component K00164,K01616 GO:0000287,GO:0003674,GO:0003824,GO:0004591,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016624,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0019842,GO:0022900,GO:0030312,GO:0030976,GO:0032991,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0048037,GO:0050439,GO:0050662,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234 1.2.4.2,4.1.1.71 0.0 1018.0
HFD3_k127_524975_1 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004221 447.0
HFD3_k127_524975_10 dihydrofolate reductase activity - - - 0.0000000000001605 80.0
HFD3_k127_524975_11 DoxX-like family - - - 0.00000004434 65.0
HFD3_k127_524975_2 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000969 224.0
HFD3_k127_524975_3 Uncharacterized conserved protein (COG2071) - - - 0.000000000000000000000000000000000000000000000000000000000002801 223.0
HFD3_k127_524975_4 MarR family - - - 0.000000000000000000000000000000000000000000000000000000000003014 213.0
HFD3_k127_524975_5 Protein of unknown function (DUF1572) - - - 0.0000000000000000000000000000000000000000000000002579 182.0
HFD3_k127_524975_6 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000001516 179.0
HFD3_k127_524975_7 DinB superfamily - - - 0.00000000000000000000000000000000000005533 150.0
HFD3_k127_524975_8 - - - - 0.0000000000000000000004199 107.0
HFD3_k127_524975_9 - - - - 0.00000000000000003298 91.0
HFD3_k127_5253874_0 transport - - - 0.0 1178.0
HFD3_k127_5253874_1 membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006188 595.0
HFD3_k127_5253874_2 Carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 414.0
HFD3_k127_5253874_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K03438,K13292 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009249,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031224,GO:0031226,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000003678 242.0
HFD3_k127_5253874_4 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000005433 209.0
HFD3_k127_5253874_5 SMART regulatory protein GntR HTH - - - 0.000000000000000000000000000000000000001195 156.0
HFD3_k127_5253874_6 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.0000000000000000000000000000000000006125 147.0
HFD3_k127_5253874_7 Calcineurin-like phosphoesterase - - - 0.0000000000001719 77.0
HFD3_k127_52739_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004664 544.0
HFD3_k127_52739_1 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005929 506.0
HFD3_k127_52739_10 cheY-homologous receiver domain - - - 0.0000000000000000000000000008393 117.0
HFD3_k127_52739_11 GYD domain - - - 0.000000000000000000000000001319 115.0
HFD3_k127_52739_12 ABC-2 family transporter protein K19341 - - 0.000000000000000000000000006288 111.0
HFD3_k127_52739_13 Helix-turn-helix domain - - - 0.0000000004902 68.0
HFD3_k127_52739_2 Alpha-2-Macroglobulin K06894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 529.0
HFD3_k127_52739_3 RND efflux system, outer membrane lipoprotein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 402.0
HFD3_k127_52739_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 394.0
HFD3_k127_52739_5 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008221 337.0
HFD3_k127_52739_6 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 338.0
HFD3_k127_52739_7 PFAM response regulator receiver K07662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003769 275.0
HFD3_k127_52739_8 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07640 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000001768 281.0
HFD3_k127_52739_9 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.0000000000000000000000000000001731 130.0
HFD3_k127_5351571_0 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 563.0
HFD3_k127_5351571_1 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009415 449.0
HFD3_k127_5351571_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004135 346.0
HFD3_k127_5353360_0 oligopeptide transporter, OPT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 300.0
HFD3_k127_5353360_1 Thioredoxin K03672 - 1.8.1.8 0.00000000000000000000000000000000000000000000000002126 182.0
HFD3_k127_5353360_2 Thioesterase superfamily - - - 0.0000000000000000000000000001121 120.0
HFD3_k127_5361590_0 Polysaccharide biosynthesis protein K01784,K08679 - 5.1.3.2,5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 374.0
HFD3_k127_5361590_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 381.0
HFD3_k127_5361590_10 Tetratricopeptide repeat K05807 - - 0.0000000000000000003182 102.0
HFD3_k127_5361590_11 PASTA K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.0000000000000004429 87.0
HFD3_k127_5361590_12 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01840 - 5.4.2.8 0.000000001468 69.0
HFD3_k127_5361590_13 positive regulation of growth rate - - - 0.00000006309 65.0
HFD3_k127_5361590_2 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006804 316.0
HFD3_k127_5361590_3 PFAM transferase hexapeptide repeat containing protein K00966 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 295.0
HFD3_k127_5361590_4 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000001208 269.0
HFD3_k127_5361590_5 Ribulose-phosphate 3 epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000001479 260.0
HFD3_k127_5361590_6 response regulator K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000001397 271.0
HFD3_k127_5361590_7 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000001755 184.0
HFD3_k127_5361590_8 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000006795 166.0
HFD3_k127_5361590_9 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000008095 129.0
HFD3_k127_53675_0 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008189 301.0
HFD3_k127_53675_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000006837 147.0
HFD3_k127_53675_2 Histidine kinase K02482,K03557 - 2.7.13.3 0.00000179 59.0
HFD3_k127_53675_3 Anti-sigma-K factor rskA - - - 0.00004294 54.0
HFD3_k127_5383019_0 Phosphate acyltransferases K01897 - 6.2.1.3 4.293e-235 776.0
HFD3_k127_5383019_1 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008349 423.0
HFD3_k127_5383019_10 TLC ATP/ADP transporter K03301 - - 0.00000000000000000000000000000000000000000000000000000000007362 232.0
HFD3_k127_5383019_11 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000648 205.0
HFD3_k127_5383019_12 Domain present in phytochromes and cGMP-specific phosphodiesterases. K08968 - 1.8.4.14 0.00000000000000000000000000000000000000003469 156.0
HFD3_k127_5383019_13 Tetratricopeptide repeat - - - 0.000000000000000000000000000002056 132.0
HFD3_k127_5383019_14 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000001203 123.0
HFD3_k127_5383019_15 Phosphate acyltransferases K00631 GO:0003674,GO:0003824,GO:0004366,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006629,GO:0006631,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0019752,GO:0031224,GO:0031226,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.3.1.15 0.00000000000000000000000003364 123.0
HFD3_k127_5383019_16 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000003671 94.0
HFD3_k127_5383019_17 Belongs to the transketolase family K00615 - 2.2.1.1 0.000000000000008473 89.0
HFD3_k127_5383019_19 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.000009605 52.0
HFD3_k127_5383019_2 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005347 358.0
HFD3_k127_5383019_3 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000552 375.0
HFD3_k127_5383019_4 DEAD-like helicases superfamily K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 356.0
HFD3_k127_5383019_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007936 314.0
HFD3_k127_5383019_6 Proline dehydrogenase K00318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001423 294.0
HFD3_k127_5383019_7 Highly conserved protein containing a thioredoxin domain K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000001754 256.0
HFD3_k127_5383019_8 TLC ATP/ADP transporter K03301 - - 0.0000000000000000000000000000000000000000000000000000000000000000005355 261.0
HFD3_k127_5383019_9 Glucokinase K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000001871 223.0
HFD3_k127_5407128_0 neuron death in response to oxidative stress K01173,K04771 - 3.4.21.107 4.494e-198 642.0
HFD3_k127_5407128_1 Trypsin-like peptidase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 574.0
HFD3_k127_5407128_10 Rhomboid family K19225 - 3.4.21.105 0.000000000000000000001816 108.0
HFD3_k127_5407128_11 PFAM Vitamin B12 dependent methionine synthase, activation - - - 0.00000000000000001533 94.0
HFD3_k127_5407128_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004764 383.0
HFD3_k127_5407128_3 cation transport ATPase K17686 - 3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005411 371.0
HFD3_k127_5407128_4 Trypsin-like peptidase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007753 336.0
HFD3_k127_5407128_5 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002888 297.0
HFD3_k127_5407128_6 - - - - 0.00000000000000000000000000000000000000000000000000000000002455 220.0
HFD3_k127_5407128_7 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000009562 198.0
HFD3_k127_5407128_8 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000008783 213.0
HFD3_k127_5407128_9 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000002009 193.0
HFD3_k127_5449896_0 TIGRFAM phosphate binding protein K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000729 391.0
HFD3_k127_5449896_1 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 391.0
HFD3_k127_5449896_10 inorganic phosphate transmembrane transporter activity K02038 - - 0.000001106 60.0
HFD3_k127_5449896_11 - - - - 0.0003898 47.0
HFD3_k127_5449896_2 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007468 357.0
HFD3_k127_5449896_3 dTDP biosynthetic process K00560,K00943,K01585 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.1.1.45,2.7.4.9,4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001309 284.0
HFD3_k127_5449896_4 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000000003853 241.0
HFD3_k127_5449896_5 - - - - 0.00000000000000000000000000000000000000000000000000000000007285 211.0
HFD3_k127_5449896_6 Haem-binding domain - - - 0.00000000000000000000000000000000000000002758 157.0
HFD3_k127_5449896_7 phosphohistidine phosphatase, SixA K08296 - - 0.00000000000000000000000008212 113.0
HFD3_k127_5449896_8 VIT family - - - 0.00000000000005711 74.0
HFD3_k127_5449896_9 CHAD domain - - - 0.0000000003285 73.0
HFD3_k127_5488163_0 major facilitator superfamily K08218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 608.0
HFD3_k127_5488163_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 437.0
HFD3_k127_5488163_10 - - - - 0.00008576 51.0
HFD3_k127_5488163_2 Belongs to the peptidase S1B family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008772 341.0
HFD3_k127_5488163_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 311.0
HFD3_k127_5488163_4 Glycogen debranching enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000004472 247.0
HFD3_k127_5488163_5 - - - - 0.0000000000000000000000000000000000000000000000473 185.0
HFD3_k127_5488163_6 photosystem II stabilization K00703,K02237,K02238 - 2.4.1.21 0.000000000000001863 85.0
HFD3_k127_5488163_7 - - - - 0.000000000002756 78.0
HFD3_k127_5488163_8 RES domain - - - 0.00000000003138 75.0
HFD3_k127_5488163_9 Type II transport protein GspH K08084 - - 0.000002937 57.0
HFD3_k127_5514303_0 Transposase - - - 0.00000000000000000000000000000009287 135.0
HFD3_k127_5514303_1 DDE superfamily endonuclease - - - 0.000000000000273 70.0
HFD3_k127_5516853_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1138.0
HFD3_k127_5516853_1 Amidohydrolase family K06015 - 3.5.1.81 3.323e-218 715.0
HFD3_k127_5516853_10 mismatched DNA binding K03555 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 402.0
HFD3_k127_5516853_11 4Fe-4S dicluster domain K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000411 361.0
HFD3_k127_5516853_12 PFAM Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007189 360.0
HFD3_k127_5516853_13 Alanine-glyoxylate amino-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 346.0
HFD3_k127_5516853_14 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005748 331.0
HFD3_k127_5516853_15 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 313.0
HFD3_k127_5516853_16 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000003813 267.0
HFD3_k127_5516853_17 beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003608 266.0
HFD3_k127_5516853_18 formate dehydrogenase (NAD+) activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000001093 237.0
HFD3_k127_5516853_19 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000007419 217.0
HFD3_k127_5516853_2 Sodium:solute symporter family - - - 5.072e-196 629.0
HFD3_k127_5516853_20 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000001437 199.0
HFD3_k127_5516853_21 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000003764 159.0
HFD3_k127_5516853_22 Tetratricopeptide repeat K01768 - 4.6.1.1 0.00000000000000000000000000000002403 143.0
HFD3_k127_5516853_23 DNA-templated transcription, initiation - - - 0.00000000000000000000000000001043 127.0
HFD3_k127_5516853_24 Polysulphide reductase, NrfD - - - 0.0000000000000000000000008553 119.0
HFD3_k127_5516853_25 protein conserved in bacteria - - - 0.000000000000002271 89.0
HFD3_k127_5516853_27 COG0607 Rhodanese-related sulfurtransferase - - - 0.00000000132 63.0
HFD3_k127_5516853_28 DinB family - - - 0.000000002859 69.0
HFD3_k127_5516853_3 Anion-transporting ATPase K01551 - 3.6.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 571.0
HFD3_k127_5516853_31 - - - - 0.000025 48.0
HFD3_k127_5516853_32 - - - - 0.0003742 52.0
HFD3_k127_5516853_33 Beta-galactosidase trimerisation domain K12308 - 3.2.1.23 0.0003748 51.0
HFD3_k127_5516853_4 aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000553 559.0
HFD3_k127_5516853_5 FAD linked oxidases, C-terminal domain K00102 - 1.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007397 555.0
HFD3_k127_5516853_6 Peptidase, M16 K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 533.0
HFD3_k127_5516853_7 D-aminoacylase domain protein K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 489.0
HFD3_k127_5516853_8 FAD linked oxidase domain protein K00102,K00104 - 1.1.2.4,1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007158 466.0
HFD3_k127_5516853_9 Insulinase (Peptidase family M16) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 399.0
HFD3_k127_5518390_0 Domain of unknown function (DUF5107) - - - 1.22e-244 796.0
HFD3_k127_5518390_1 PFAM Amidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 526.0
HFD3_k127_5518390_10 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain - - - 0.00000000000000000000000000008287 119.0
HFD3_k127_5518390_11 Haem-binding domain - - - 0.00000000000000000000000000009018 121.0
HFD3_k127_5518390_12 Endoribonuclease L-PSP K09021 - - 0.00000000000000000003483 103.0
HFD3_k127_5518390_13 Endoribonuclease L-PSP - - - 0.0000000000000000003627 100.0
HFD3_k127_5518390_14 amine dehydrogenase activity K09022 - 3.5.99.10 0.000000000005174 78.0
HFD3_k127_5518390_2 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009639 256.0
HFD3_k127_5518390_3 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000005823 241.0
HFD3_k127_5518390_4 COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000008688 227.0
HFD3_k127_5518390_5 Penicillin-binding protein 1A K05366,K21464 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000004712 212.0
HFD3_k127_5518390_6 DNA-templated transcription, initiation - - - 0.00000000000000000000000000000000000000000000000000000004228 215.0
HFD3_k127_5518390_7 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000009533 188.0
HFD3_k127_5518390_8 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000004741 174.0
HFD3_k127_5518390_9 - - - - 0.0000000000000000000000000000000001971 151.0
HFD3_k127_5530282_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.000000000000000000000000003112 111.0
HFD3_k127_5530282_1 PHP domain protein - - - 0.0000000000000000001563 103.0
HFD3_k127_5540605_0 Glutamine synthetase type III K01915 - 6.3.1.2 8.435e-307 956.0
HFD3_k127_5540605_1 Aldo/keto reductase family K05882 - 1.1.1.91 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 478.0
HFD3_k127_5540605_2 Alcohol dehydrogenase GroES-like domain K00008,K00148,K18369 - 1.1.1.14,1.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 461.0
HFD3_k127_5540605_3 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 322.0
HFD3_k127_5540605_4 divalent heavy-metal cations transporter - - - 0.00000000000000000000000000000000000000000000002884 180.0
HFD3_k127_5540605_5 Cys-tRNA(Pro) hydrolase activity K19055 - - 0.0000000000000000000000000000000001878 138.0
HFD3_k127_5540605_6 Transcriptional regulator PadR-like family - - - 0.0000000000000000000008324 100.0
HFD3_k127_5540605_7 NYN domain - - - 0.0000000000000000001131 100.0
HFD3_k127_5540605_8 AMP binding - - - 0.0000000000000003371 91.0
HFD3_k127_5555009_0 hydrolase, family 3 K05349 - 3.2.1.21 0.0 1107.0
HFD3_k127_5555009_1 Periplasmic copper-binding protein (NosD) - - - 2.759e-231 732.0
HFD3_k127_5555009_2 endo-1,4-beta-xylanase activity K01181 - 3.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003669 345.0
HFD3_k127_5555009_3 Transcriptional regulator K07727 - - 0.00000000000000000000000963 108.0
HFD3_k127_5567944_0 PFAM Pyrrolo-quinoline quinone K00117 - 1.1.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005593 582.0
HFD3_k127_5567944_1 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 563.0
HFD3_k127_5567944_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000126 269.0
HFD3_k127_5567944_3 Histone methylation protein DOT1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001499 244.0
HFD3_k127_5567944_4 Low affinity iron permease - - - 0.000000000000000000000000000000000000000001012 160.0
HFD3_k127_5567944_5 Surface antigen - - - 0.0000000000000000109 96.0
HFD3_k127_5571168_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 4.19e-247 770.0
HFD3_k127_5571168_1 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007589 601.0
HFD3_k127_5571168_13 Transcriptional regulator PadR-like family - - - 0.00000006482 59.0
HFD3_k127_5571168_14 aminopeptidase K05994 - 3.4.11.10 0.0000002419 61.0
HFD3_k127_5571168_15 - - - - 0.0000003128 61.0
HFD3_k127_5571168_16 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.000002623 55.0
HFD3_k127_5571168_2 Belongs to the citrate synthase family K01647 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 441.0
HFD3_k127_5571168_3 Belongs to the MIP aquaporin (TC 1.A.8) family K02440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 335.0
HFD3_k127_5571168_4 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 336.0
HFD3_k127_5571168_5 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000003767 173.0
HFD3_k127_5571168_6 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000000309 151.0
HFD3_k127_5571168_7 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309 - - 0.00000000000000000000000001006 112.0
HFD3_k127_5571168_8 DNA-templated transcription, initiation - - - 0.000000000000000000001276 102.0
HFD3_k127_5571168_9 PAS fold - - - 0.00000000000000000001922 108.0
HFD3_k127_5606145_0 alpha-L-rhamnosidase - - - 9.215e-216 684.0
HFD3_k127_5626776_0 GMC oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004294 547.0
HFD3_k127_5626776_1 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 415.0
HFD3_k127_5626776_10 Domain of unknown function (DUF4956) - - - 0.0000000000003593 76.0
HFD3_k127_5626776_2 PLD-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 296.0
HFD3_k127_5626776_3 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 300.0
HFD3_k127_5626776_4 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000006088 225.0
HFD3_k127_5626776_5 Protein of unknown function (DUF520) K09767 - - 0.0000000000000000000000000000000000000000000000000000001456 210.0
HFD3_k127_5626776_6 PFAM Uncharacterised protein family (UPF0227) K07000 - - 0.0000000000000000000000000000000000000000000156 170.0
HFD3_k127_5626776_7 Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX MLL subfamily - GO:0005575,GO:0005911,GO:0008150,GO:0009292,GO:0009294,GO:0009506,GO:0009893,GO:0009987,GO:0010604,GO:0010638,GO:0019222,GO:0030054,GO:0031056,GO:0031058,GO:0031060,GO:0031062,GO:0031323,GO:0031325,GO:0031399,GO:0031401,GO:0032268,GO:0032270,GO:0033043,GO:0033044,GO:0044764,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051569,GO:0051571,GO:0051704,GO:0055044,GO:0060255,GO:0065007,GO:0080090,GO:1902275,GO:1905269,GO:2001252 - 0.00000000000000000000001833 105.0
HFD3_k127_5626776_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000007846 105.0
HFD3_k127_5626776_9 - - - - 0.0000000000000000002115 96.0
HFD3_k127_5635845_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007878 570.0
HFD3_k127_5635845_1 GTP-binding protein TypA K06207 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 543.0
HFD3_k127_5635845_2 Cytochrome b(C-terminal)/b6/petD K00412 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005594 346.0
HFD3_k127_5635845_3 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000009942 136.0
HFD3_k127_5635845_4 AMP-dependent synthetase - - - 0.000000000000000000000000000008112 134.0
HFD3_k127_5635845_5 Rieske [2Fe-2S] domain K03886 - - 0.00000000000000000005722 96.0
HFD3_k127_5635845_6 dehydrogenase subunit - - - 0.00000000000000001064 96.0
HFD3_k127_5635845_7 deoxyhypusine monooxygenase activity - - - 0.000000000002795 79.0
HFD3_k127_5635845_8 OprF membrane domain K03286 - - 0.0000005003 58.0
HFD3_k127_5635845_9 - - - - 0.000001305 61.0
HFD3_k127_5646413_0 Alpha amylase, catalytic domain - - - 1.276e-209 670.0
HFD3_k127_5646413_1 Glycosyl hydrolases family 43 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 534.0
HFD3_k127_5646413_2 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 445.0
HFD3_k127_5646413_3 cytochrome p450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 432.0
HFD3_k127_5646413_4 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004045 369.0
HFD3_k127_5646413_5 MerR, DNA binding K13639 - - 0.00000000000000000000000000000000000000000000000000000000000001934 217.0
HFD3_k127_5665943_0 Involved in the tonB-independent uptake of proteins K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006252 457.0
HFD3_k127_5665943_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 444.0
HFD3_k127_5665943_2 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005027 330.0
HFD3_k127_5665943_3 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit K01768,K07315 - 3.1.3.3,4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000664 321.0
HFD3_k127_5665943_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000322 224.0
HFD3_k127_5665943_5 DNA topoisomerase (ATP-hydrolyzing) inhibitor activity K13652,K13653 - - 0.0000000000000000000000000000000000000004117 155.0
HFD3_k127_5665943_6 energy transducer activity K02487,K03832,K06596 - - 0.0000000000005985 74.0
HFD3_k127_5697992_0 Common central domain of tyrosinase K00505 - 1.14.18.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000696 616.0
HFD3_k127_5697992_1 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 614.0
HFD3_k127_5697992_2 Amidohydrolase family K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 521.0
HFD3_k127_5697992_3 converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 392.0
HFD3_k127_5697992_4 TonB-dependent Receptor Plug Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 372.0
HFD3_k127_5697992_5 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009654 303.0
HFD3_k127_5697992_6 Metal-binding integral membrane protein - - - 0.000000000000000000000000000000000000000000000000007199 192.0
HFD3_k127_5697992_7 LGFP repeat - - - 0.000000000000000000000000000002873 131.0
HFD3_k127_5697992_8 alginic acid biosynthetic process K01795,K07218,K12287 - 5.1.3.37 0.0000000004193 64.0
HFD3_k127_5737604_0 Glycosyl-hydrolase 97 N-terminal K01187 - 3.2.1.20 9.99e-226 717.0
HFD3_k127_5737604_1 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000000000000000000000000000000001305 235.0
HFD3_k127_575478_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002847 479.0
HFD3_k127_575478_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 354.0
HFD3_k127_575478_2 Binding-protein-dependent transport system inner membrane component K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000641 325.0
HFD3_k127_575478_3 Protein of unknown function DUF47 K02039,K07220 GO:0000287,GO:0001558,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006873,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009628,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010563,GO:0010605,GO:0010629,GO:0010966,GO:0016020,GO:0016036,GO:0019220,GO:0019222,GO:0019725,GO:0019897,GO:0019898,GO:0022898,GO:0030002,GO:0030145,GO:0030320,GO:0030643,GO:0031323,GO:0031324,GO:0031667,GO:0031668,GO:0031669,GO:0032409,GO:0032410,GO:0032412,GO:0032413,GO:0032879,GO:0033554,GO:0034605,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0040008,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043269,GO:0043271,GO:0044070,GO:0044092,GO:0044419,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045936,GO:0046677,GO:0046872,GO:0046914,GO:0046983,GO:0048519,GO:0048523,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051174,GO:0051704,GO:0051716,GO:0055062,GO:0055081,GO:0055082,GO:0055083,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071496,GO:0071944,GO:0072501,GO:0072502,GO:0072505,GO:0072506,GO:0098771,GO:0104004,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.0000000000000000000000000000000000000000000000000000000000000000003292 239.0
HFD3_k127_575478_4 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.000000000001007 73.0
HFD3_k127_58011_0 peptidase S9 prolyl oligopeptidase active site K01303 - 3.4.19.1 1.574e-306 952.0
HFD3_k127_58011_1 Protein of unknown function (DUF1553) - - - 3.222e-286 905.0
HFD3_k127_58011_10 DNA-binding transcription factor activity - - - 0.00000000000000000000003571 104.0
HFD3_k127_58011_2 Protein of unknown function (DUF1501) - - - 1.556e-229 719.0
HFD3_k127_58011_3 TonB dependent receptor K02014,K16089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 462.0
HFD3_k127_58011_4 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 392.0
HFD3_k127_58011_5 Peptidoglycan-binding domain 1 protein K08305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002026 269.0
HFD3_k127_58011_7 glyoxalase III activity - - - 0.000000000000000000000000005161 116.0
HFD3_k127_58011_8 Domain of unknown function (DUF4154) - - - 0.00000000000000000000000257 118.0
HFD3_k127_58011_9 Na -dependent transporter K03453 - - 0.000000000000000000000005791 112.0
HFD3_k127_5810085_0 peptidase dimerisation domain protein K01436 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003788 493.0
HFD3_k127_5810085_1 PFAM UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 431.0
HFD3_k127_5810085_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 449.0
HFD3_k127_5810085_3 Belongs to the cysteine synthase cystathionine beta- synthase family K12339,K21148 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.113,2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 383.0
HFD3_k127_5810085_4 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 365.0
HFD3_k127_5810085_5 PFAM Endonuclease Exonuclease phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006769 273.0
HFD3_k127_5810085_6 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000001303 275.0
HFD3_k127_5810085_7 JAB/MPN domain - - - 0.000000000000000000000000000002275 129.0
HFD3_k127_5810085_8 PFAM helix-turn-helix- domain containing protein, AraC type - - - 0.00000000000000000000003951 105.0
HFD3_k127_5811489_0 Carboxypeptidase regulatory-like domain - - - 1.305e-275 880.0
HFD3_k127_5811489_1 mandelate racemase muconate lactonizing K01684,K01781,K08323 - 4.2.1.6,4.2.1.8,5.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 595.0
HFD3_k127_5811489_2 glucuronate isomerase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008075 445.0
HFD3_k127_5811489_3 electron transfer activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 435.0
HFD3_k127_5811489_4 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005899 333.0
HFD3_k127_5811489_5 PFAM ROK family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005418 338.0
HFD3_k127_5811489_6 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000004835 179.0
HFD3_k127_5816065_0 ABC transporter K15738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006943 448.0
HFD3_k127_5816065_1 Required for morphogenesis under gluconeogenic growth conditions - - - 0.000000000000000000000000000000000000000000000004031 187.0
HFD3_k127_5816065_2 COG1512 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.00000000000000002953 87.0
HFD3_k127_5816065_3 Domain of unknown function (DUF4920) - - - 0.000000000000003042 90.0
HFD3_k127_5816065_4 nucleotidyltransferase activity - - - 0.0000000000001111 83.0
HFD3_k127_5835371_0 symporter activity K03307 - - 4.828e-256 801.0
HFD3_k127_5835371_1 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 549.0
HFD3_k127_5835371_2 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004658 399.0
HFD3_k127_5835371_3 HupE / UreJ protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001062 286.0
HFD3_k127_5835371_4 PFAM Aminotransferase class I and II K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000001566 215.0
HFD3_k127_5835371_5 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000008226 205.0
HFD3_k127_5835371_6 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000002067 147.0
HFD3_k127_5835371_7 SMART serine threonine protein kinase - - - 0.0000003248 52.0
HFD3_k127_5835371_8 oxidoreductase activity - - - 0.000001544 58.0
HFD3_k127_5838227_0 D,D-heptose 1,7-bisphosphate phosphatase K02841,K02843,K02849,K03271,K03272,K03273 - 2.7.1.167,2.7.7.70,3.1.3.82,3.1.3.83,5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000002756 224.0
HFD3_k127_5838227_1 Lipid A biosynthesis K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000008974 188.0
HFD3_k127_5838227_2 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000002364 163.0
HFD3_k127_5838227_3 TIGRFAM D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000281 149.0
HFD3_k127_5845813_0 Belongs to the glycosyl hydrolase 31 family K07407 - 3.2.1.22 2.929e-240 752.0
HFD3_k127_5845813_1 PFAM Radical SAM - - - 3.07e-216 684.0
HFD3_k127_5845813_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005703 323.0
HFD3_k127_5845813_3 - - - - 0.00000000000000000000000000000000002141 152.0
HFD3_k127_5845813_4 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000000000000001373 136.0
HFD3_k127_5845813_5 deoxyhypusine monooxygenase activity - - - 0.00000000000000000002131 105.0
HFD3_k127_5845813_6 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000001515 72.0
HFD3_k127_5850344_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 413.0
HFD3_k127_5850344_1 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000003573 254.0
HFD3_k127_5850344_2 Dehydrogenase E1 component K11381 - 1.2.4.4 0.000000000000000000000000000000000000000000000000005141 186.0
HFD3_k127_5850344_3 PFAM Rhomboid family - - - 0.0000000000000000000000000000000000000000001743 168.0
HFD3_k127_5850344_4 PFAM Major Facilitator Superfamily K08223 - - 0.000000000000000000000000000000000000000004093 173.0
HFD3_k127_5850344_5 Cupin domain - - - 0.000000000000000000000000000000000001846 143.0
HFD3_k127_5850344_6 Yqey-like protein K09117 - - 0.000000000000000000000313 99.0
HFD3_k127_5851468_0 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 3.764e-212 672.0
HFD3_k127_5851468_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000724 561.0
HFD3_k127_5851468_10 PFAM heat shock protein DnaJ domain protein - - - 0.000000000001596 79.0
HFD3_k127_5851468_2 Type II IV secretion system protein K02454,K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 469.0
HFD3_k127_5851468_3 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009743 344.0
HFD3_k127_5851468_4 COG0444 ABC-type dipeptide oligopeptide nickel transport system, ATPase component K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 350.0
HFD3_k127_5851468_5 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 349.0
HFD3_k127_5851468_6 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000002497 262.0
HFD3_k127_5851468_7 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000006733 167.0
HFD3_k127_5851468_8 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000119 132.0
HFD3_k127_5851468_9 23S rRNA-intervening sequence protein - - - 0.00000000000000000002963 97.0
HFD3_k127_5853680_0 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 374.0
HFD3_k127_5853680_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008213 342.0
HFD3_k127_5853680_2 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000003536 274.0
HFD3_k127_5853680_3 Deoxynucleoside kinase K15518 - 2.7.1.113 0.0000000000000000000000000000000000000000000000000000000143 209.0
HFD3_k127_5853680_4 fumarate reductase K00239 - 1.3.5.1,1.3.5.4 0.00002519 57.0
HFD3_k127_5860835_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 3.141e-295 920.0
HFD3_k127_5860835_1 MgsA AAA+ ATPase C terminal K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008352 510.0
HFD3_k127_5860835_10 RNA 2'-O ribose methyltransferase substrate binding K03437 - - 0.0000000000000000000000000000000000000000007222 171.0
HFD3_k127_5860835_11 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000009545 156.0
HFD3_k127_5860835_12 von Willebrand factor, type A - - - 0.00000000000000000000000000003219 136.0
HFD3_k127_5860835_13 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.000000000000000000000000001077 125.0
HFD3_k127_5860835_15 YtxH-like protein - - - 0.0001444 49.0
HFD3_k127_5860835_16 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030163,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051603,GO:0061077,GO:0070011,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.21.107 0.000273 52.0
HFD3_k127_5860835_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 434.0
HFD3_k127_5860835_3 Cys/Met metabolism PLP-dependent enzyme K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004003 340.0
HFD3_k127_5860835_4 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006884 330.0
HFD3_k127_5860835_5 Belongs to the MlaE permease family K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005633 255.0
HFD3_k127_5860835_6 PFAM phosphoesterase, RecJ domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001838 248.0
HFD3_k127_5860835_7 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000001419 244.0
HFD3_k127_5860835_8 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000001103 223.0
HFD3_k127_5860835_9 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000003118 179.0
HFD3_k127_5865533_0 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 332.0
HFD3_k127_5865533_1 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003894 306.0
HFD3_k127_5865533_2 Bacterial sugar transferase K03606 - - 0.000000000000000000000000000006684 133.0
HFD3_k127_5869600_0 MacB-like periplasmic core domain - - - 6.348e-302 950.0
HFD3_k127_5869600_1 Domain of unknown function (DUF5107) - - - 1.909e-269 883.0
HFD3_k127_5869600_10 Amino acid permease - - - 0.0000000000000000000000000000000000000000014 161.0
HFD3_k127_5869600_11 domain protein - - - 0.0000000000000000000000000000000001792 145.0
HFD3_k127_5869600_12 TIR domain - - - 0.000000000000000000000000000003669 134.0
HFD3_k127_5869600_13 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000006768 112.0
HFD3_k127_5869600_14 Alpha-L-fucosidase K01206,K21449 - 3.2.1.51 0.00000000000000008191 88.0
HFD3_k127_5869600_15 - - - - 0.000000000000002396 88.0
HFD3_k127_5869600_17 Mismatch repair ATPase (MutS family) - - - 0.00000000000007962 77.0
HFD3_k127_5869600_18 ATPase domain of DNA mismatch repair MUTS family - - - 0.00001192 57.0
HFD3_k127_5869600_2 amine dehydrogenase activity - - - 5.293e-204 668.0
HFD3_k127_5869600_3 Glycosyl hydrolases family 15 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 575.0
HFD3_k127_5869600_4 siderophore transport K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004376 558.0
HFD3_k127_5869600_5 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000326 540.0
HFD3_k127_5869600_6 GMP synthase (glutamine-hydrolyzing) activity K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 490.0
HFD3_k127_5869600_7 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 327.0
HFD3_k127_5869600_8 Domain of unknown function (DUF4091) - - - 0.000000000000000000000000000000000000000000000000000000000004973 237.0
HFD3_k127_5869600_9 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000002639 231.0
HFD3_k127_5873909_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1052.0
HFD3_k127_5873909_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 7.908e-289 909.0
HFD3_k127_5873909_10 Phosphomethylpyrimidine kinase K00868,K00941,K03147,K21219 GO:0008150,GO:0040007 2.5.1.3,2.7.1.35,2.7.1.49,2.7.4.7,4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000003383 273.0
HFD3_k127_5873909_11 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009391 263.0
HFD3_k127_5873909_12 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000445 229.0
HFD3_k127_5873909_13 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000004656 224.0
HFD3_k127_5873909_14 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000001403 215.0
HFD3_k127_5873909_15 MotA TolQ ExbB proton channel K03561,K03562 - - 0.0000000000000000000000000000000000000000000000000000000001699 222.0
HFD3_k127_5873909_16 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000003214 213.0
HFD3_k127_5873909_17 PFAM Histidine triad (HIT) protein K02503 - - 0.00000000000000000000000000000000000000000000001359 172.0
HFD3_k127_5873909_18 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000000000001258 169.0
HFD3_k127_5873909_19 carboxylic acid catabolic process - - - 0.000000000000000000000000000000000000000000723 176.0
HFD3_k127_5873909_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 5.366e-251 795.0
HFD3_k127_5873909_20 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000006133 169.0
HFD3_k127_5873909_21 MoaE protein K21142 - 2.8.1.12 0.0000000000000000000000000000000000002004 150.0
HFD3_k127_5873909_22 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0000000000000000000000000000000003959 140.0
HFD3_k127_5873909_23 - - - - 0.000000000000000000000000000000009574 136.0
HFD3_k127_5873909_24 Hydrolase, NUDIX family K01515 - 3.6.1.13 0.00000000000000000000000000000001306 132.0
HFD3_k127_5873909_25 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000001131 123.0
HFD3_k127_5873909_26 BioY family K03523 - - 0.00000000000000000000000005516 122.0
HFD3_k127_5873909_27 Tetratricopeptide repeat - - - 0.0000000000000000000000002146 124.0
HFD3_k127_5873909_28 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.000000000000000000000003463 108.0
HFD3_k127_5873909_29 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.00000000000000000000002453 110.0
HFD3_k127_5873909_3 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 455.0
HFD3_k127_5873909_30 transcriptional regulator K07979 - - 0.000000000000000000001215 98.0
HFD3_k127_5873909_31 Mo-molybdopterin cofactor metabolic process K03636,K03637,K03752,K21142 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.77,2.8.1.12,4.6.1.17 0.0000000000000008044 83.0
HFD3_k127_5873909_32 - - - - 0.000000000000001557 85.0
HFD3_k127_5873909_33 Preprotein translocase subunit K03210 - - 0.000000000000004312 79.0
HFD3_k127_5873909_34 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000004326 83.0
HFD3_k127_5873909_35 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000508 86.0
HFD3_k127_5873909_36 Tetratricopeptide repeat - - - 0.0000001536 63.0
HFD3_k127_5873909_37 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000007376 54.0
HFD3_k127_5873909_38 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.0000026 52.0
HFD3_k127_5873909_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006563 443.0
HFD3_k127_5873909_5 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 429.0
HFD3_k127_5873909_6 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008741 404.0
HFD3_k127_5873909_7 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004573 362.0
HFD3_k127_5873909_8 PFAM band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 335.0
HFD3_k127_5873909_9 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 293.0
HFD3_k127_5904200_0 efflux transmembrane transporter activity - - - 3.564e-221 711.0
HFD3_k127_5904200_1 lysine biosynthetic process via aminoadipic acid - - - 6.698e-199 650.0
HFD3_k127_5904200_2 Protein of unknown function (DUF2961) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 498.0
HFD3_k127_5904200_3 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006669 316.0
HFD3_k127_5904200_4 Peptidase M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 319.0
HFD3_k127_5904200_5 PFAM PEBP family protein K06910 - - 0.000000000000000007208 85.0
HFD3_k127_5904200_6 Involved in the tonB-independent uptake of proteins K12132 - 2.7.11.1 0.000006735 53.0
HFD3_k127_5904200_7 PFAM SMP-30 Gluconolaconase - - - 0.00005735 56.0
HFD3_k127_59304_0 Belongs to the PEP-utilizing enzyme family K01006,K22424 - 2.7.3.13,2.7.9.1 8.01e-279 876.0
HFD3_k127_59304_1 Acts as a magnesium transporter K03281,K04767,K06213,K15986 GO:0000287,GO:0003674,GO:0005488,GO:0005515,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015693,GO:0030001,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0051179,GO:0051234,GO:0070838,GO:0072511 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 396.0
HFD3_k127_59304_2 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 382.0
HFD3_k127_59304_3 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009053 385.0
HFD3_k127_59304_4 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004585 303.0
HFD3_k127_59304_5 Transporter associated domain K06189 - - 0.000000000000000000000000000000000000000000000000000000000003647 225.0
HFD3_k127_59304_6 Involved in DNA repair and RecF pathway recombination K03474,K03584 GO:0008150,GO:0009314,GO:0009628,GO:0050896 2.6.99.2 0.00000000000000000006243 104.0
HFD3_k127_59304_7 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000001583 59.0
HFD3_k127_5943559_0 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 488.0
HFD3_k127_5943559_1 homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000676 331.0
HFD3_k127_5943559_10 23S rRNA-intervening sequence protein - - - 0.000004625 57.0
HFD3_k127_5943559_2 Histidine kinase internal region K02478 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 325.0
HFD3_k127_5943559_3 Dimerisation domain of Zinc Transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005412 255.0
HFD3_k127_5943559_4 Two component transcriptional regulator, LytTR family K02477,K07705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001665 256.0
HFD3_k127_5943559_5 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000003313 235.0
HFD3_k127_5943559_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00337,K00338 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000001654 175.0
HFD3_k127_5943559_7 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000001289 170.0
HFD3_k127_5943559_8 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000038 161.0
HFD3_k127_5943559_9 phosphoesterases, related to the Icc protein - - - 0.000000000000000000000012 110.0
HFD3_k127_5973768_0 Berberine and berberine like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 542.0
HFD3_k127_5973768_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000923 440.0
HFD3_k127_5973768_2 arylsulfatase A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 387.0
HFD3_k127_5973768_3 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002851 284.0
HFD3_k127_6005008_0 6-phosphogluconate dehydrogenase, NAD-binding K00020,K00042 - 1.1.1.31,1.1.1.60 0.000000000000000000000000000000000000000000000000000000000000000000000000001767 269.0
HFD3_k127_6005008_1 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000007964 196.0
HFD3_k127_6005008_2 PFAM SAF domain K02279 - - 0.0000000000000000000000000000002196 130.0
HFD3_k127_6005008_3 peptidase A24A prepilin type IV K02278 - 3.4.23.43 0.0000000000000000000182 97.0
HFD3_k127_6005008_4 TadE-like protein - - - 0.0000001937 58.0
HFD3_k127_6005008_5 Flp Fap pilin component - - - 0.000002505 57.0
HFD3_k127_6005008_6 TadE-like protein - - - 0.000003287 60.0
HFD3_k127_6005008_7 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00042 - 1.1.1.60 0.000004904 51.0
HFD3_k127_6005008_8 PFAM 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) - - - 0.000007552 55.0
HFD3_k127_6007809_0 Cytochrome c-type biogenesis protein CcmF C-terminal K02198 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007803 552.0
HFD3_k127_6007809_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004765 459.0
HFD3_k127_6007809_11 Protein of unknown function (DUF721) - - - 0.0000478 49.0
HFD3_k127_6007809_2 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000008534 232.0
HFD3_k127_6007809_3 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.000000000000000000000000000000000000000000000000000000000001258 224.0
HFD3_k127_6007809_4 Cytochrome C assembly protein K02195 - - 0.0000000000000000000000000000000000000000000000000001883 194.0
HFD3_k127_6007809_5 ATPases associated with a variety of cellular activities K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000001144 182.0
HFD3_k127_6007809_6 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000001127 171.0
HFD3_k127_6007809_7 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000006625 79.0
HFD3_k127_6007809_8 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000003779 76.0
HFD3_k127_6007809_9 - - - - 0.00000000005006 73.0
HFD3_k127_6008102_0 serine-type peptidase activity - - - 3.303e-252 811.0
HFD3_k127_6008102_1 asparaginase K01424,K01444,K13051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.19.5,3.5.1.1,3.5.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008175 463.0
HFD3_k127_6008102_2 aminopeptidase activity K01266 - 3.4.11.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000502 419.0
HFD3_k127_6008102_3 Carbohydrate phosphorylase K00688 - 2.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 293.0
HFD3_k127_6008102_4 beta' subunit K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000001738 250.0
HFD3_k127_6008102_5 Protease prsW family - - - 0.00000000000000000000000000000000000000000000000000004153 200.0
HFD3_k127_6039225_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 8.009e-227 719.0
HFD3_k127_6039225_1 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 457.0
HFD3_k127_6039225_2 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003372 348.0
HFD3_k127_6039225_3 RES - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 341.0
HFD3_k127_6039225_4 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000003315 133.0
HFD3_k127_6039225_5 Binds the 23S rRNA K02909 - - 0.00000000000000000000000002838 111.0
HFD3_k127_605791_0 Pectic acid lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002877 317.0
HFD3_k127_605791_1 Glycosyl transferase family 2 - - - 0.000164 53.0
HFD3_k127_6101228_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1396.0
HFD3_k127_6101228_1 Acetolactate synthase, large subunit K01652 - 2.2.1.6 2.316e-275 858.0
HFD3_k127_6101228_10 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000001553 207.0
HFD3_k127_6101228_11 ACT domain K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000003238 193.0
HFD3_k127_6101228_12 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.000000000000000000000000000000000000000177 160.0
HFD3_k127_6101228_13 Transcriptional regulator - - - 0.000000000000000000000000000000000000002742 158.0
HFD3_k127_6101228_2 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 3.462e-243 762.0
HFD3_k127_6101228_3 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006103,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006520,GO:0006544,GO:0006546,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009071,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015036,GO:0016054,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0017144,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019464,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036094,GO:0036211,GO:0042133,GO:0042135,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0043648,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045250,GO:0045252,GO:0045254,GO:0046390,GO:0046395,GO:0046483,GO:0046496,GO:0046872,GO:0046914,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0065007,GO:0065008,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0097159,GO:0106077,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 7.776e-201 637.0
HFD3_k127_6101228_4 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 601.0
HFD3_k127_6101228_5 von Willebrand factor (vWF) type A domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002295 489.0
HFD3_k127_6101228_6 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008135 471.0
HFD3_k127_6101228_7 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 391.0
HFD3_k127_6101228_8 Belongs to the UPF0173 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002718 256.0
HFD3_k127_6101228_9 UreE urease accessory protein, C-terminal domain K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000002962 246.0
HFD3_k127_6130974_0 negative regulation of protein lipidation K19294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004608 566.0
HFD3_k127_6130974_1 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 327.0
HFD3_k127_6130974_2 SGNH hydrolase-like domain, acetyltransferase AlgX K19295 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002978 289.0
HFD3_k127_6134796_0 PFAM Formiminotransferase K00603 - 2.1.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 359.0
HFD3_k127_6134796_1 Belongs to the CinA family K03742 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 331.0
HFD3_k127_6134796_2 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 301.0
HFD3_k127_6134796_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000001389 198.0
HFD3_k127_6134796_4 Two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.0000000000000000000000000000000000000000000003814 171.0
HFD3_k127_6134796_5 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000001136 143.0
HFD3_k127_6134796_6 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000000002425 128.0
HFD3_k127_6134796_7 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000001419 123.0
HFD3_k127_6187846_0 Enoyl-CoA hydratase/isomerase K15513 - 4.1.2.44 2.316e-221 699.0
HFD3_k127_6187846_1 benzoyl-CoA oxygenase K15512 - 1.14.13.208 5.566e-208 655.0
HFD3_k127_6187846_2 Belongs to the aldehyde dehydrogenase family K00128,K00138 - 1.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 579.0
HFD3_k127_6187846_3 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000935 501.0
HFD3_k127_6187846_4 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004705 427.0
HFD3_k127_6187846_5 amino acid-binding ACT domain protein K04518 - 4.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009135 292.0
HFD3_k127_6187846_6 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008313 274.0
HFD3_k127_6187846_7 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K15546 - - 0.0000000000000000000000000000000000000000000000000000000007885 220.0
HFD3_k127_6187846_8 Heparinase II/III-like protein - - - 0.00000000000000000000000000007496 135.0
HFD3_k127_6187846_9 PFAM PIN domain - - - 0.000000000004459 72.0
HFD3_k127_6188788_0 Protein of unknown function (DUF521) K09123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 577.0
HFD3_k127_6188788_1 candidate rhamnogalacturonan lyase, polysaccharide lyase family 11 protein K01238 K18197 - 4.2.2.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 456.0
HFD3_k127_6188788_10 Major Facilitator Superfamily - - - 0.00000098 53.0
HFD3_k127_6188788_11 lactoylglutathione lyase activity - - - 0.0002156 53.0
HFD3_k127_6188788_2 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 433.0
HFD3_k127_6188788_3 DNA ligase K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003518 388.0
HFD3_k127_6188788_4 ATP dependent DNA ligase C terminal region K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000004017 254.0
HFD3_k127_6188788_5 PFAM phospholipase Carboxylesterase K06999 - - 0.000000000000000000000000000000000000000000000000000000000227 216.0
HFD3_k127_6188788_6 Protein of unknown function (DUF1684) K09164 - - 0.00000000000000000000000000000000000000000000000000006871 197.0
HFD3_k127_6188788_7 Disulphide isomerase - - - 0.00000000000000000000000000000000000000000000000001033 183.0
HFD3_k127_6188788_8 Protein of unknown function DUF126 K09128 - - 0.000000000000000000000000000000000000009436 164.0
HFD3_k127_6188788_9 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000000000000004634 136.0
HFD3_k127_6195708_0 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 579.0
HFD3_k127_6195708_1 negative regulation of transcription, DNA-templated - - - 0.00000000000000000000000000000000000000000000004089 171.0
HFD3_k127_6195708_2 Probably functions as a manganese efflux pump - - - 0.0000000000000000000000000000000000000000000003288 186.0
HFD3_k127_6195708_3 DinB family - - - 0.000000000000000000000000000000000000001359 163.0
HFD3_k127_6195708_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000007947 81.0
HFD3_k127_6232832_0 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006881 391.0
HFD3_k127_6232832_1 tRNA synthetases class I (E and Q), catalytic domain K01894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 300.0
HFD3_k127_6232832_2 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003065 292.0
HFD3_k127_6232832_3 Proline dehydrogenase K00318 - - 0.000000000000000000000000000000000000000000000000000000000000000000001099 248.0
HFD3_k127_6232832_4 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000007489 185.0
HFD3_k127_6232832_5 surface antigen (D15) K07278 - - 0.0000001267 58.0
HFD3_k127_6270723_0 Heavy metal translocating P-type atpase K01534 - 3.6.3.3,3.6.3.5 1.378e-196 634.0
HFD3_k127_6270723_1 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 360.0
HFD3_k127_6270723_10 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00003241 48.0
HFD3_k127_6270723_2 ABC-type uncharacterized transport system K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 352.0
HFD3_k127_6270723_3 PFAM asparagine synthase K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002059 274.0
HFD3_k127_6270723_4 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009559 265.0
HFD3_k127_6270723_5 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000007988 284.0
HFD3_k127_6270723_6 Domain of unknown function (DUF4340) - - - 0.000000000000000000000000000000000000000005617 171.0
HFD3_k127_6270723_7 PFAM regulatory protein, ArsR K21903 - - 0.00000000000000000000000003375 114.0
HFD3_k127_6270723_9 Sigma-54 interaction domain K02481,K07714 - - 0.000002965 57.0
HFD3_k127_6276331_0 cytochrome c oxidase subunit I K02274 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 505.0
HFD3_k127_6276331_1 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001792 265.0
HFD3_k127_6276331_2 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000007185 250.0
HFD3_k127_6276331_3 Cytochrome C oxidase subunit II, periplasmic domain K02275 - 1.9.3.1 0.0000000000000000000000000000000000003098 145.0
HFD3_k127_6276331_4 FAD dependent oxidoreductase - - - 0.00000000000000000001005 105.0
HFD3_k127_6276331_5 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.0000000000000000001648 89.0
HFD3_k127_6291088_0 Prolyl oligopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 614.0
HFD3_k127_6291088_1 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 443.0
HFD3_k127_6291088_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000001129 183.0
HFD3_k127_6291088_3 Phosphate acyltransferases - - - 0.0000000000000000000000000000000005937 148.0
HFD3_k127_6291088_4 - K06921 - - 0.000000000000149 76.0
HFD3_k127_6301377_0 protein secretion by the type I secretion system K11085 - - 1.923e-243 779.0
HFD3_k127_6301377_1 COG0488 ATPase components of ABC transporters with duplicated ATPase domains K15738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008159 584.0
HFD3_k127_6301377_2 HAD-superfamily hydrolase, subfamily IIB - - - 0.000000000000000000000000000000000000000000000000007648 194.0
HFD3_k127_6301377_3 TonB-dependent receptor plug domain K02014 - - 0.00000003614 66.0
HFD3_k127_6313025_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 7.949e-313 972.0
HFD3_k127_6313025_1 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006274 436.0
HFD3_k127_6313025_2 N-6 DNA Methylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004896 328.0
HFD3_k127_6313025_3 PFAM helicase domain protein - - - 0.00000000000000000000000000000000000000000000000000000122 218.0
HFD3_k127_6315181_0 copper-translocating P-type ATPase K17686 - 3.6.3.54 1.912e-255 807.0
HFD3_k127_6315181_1 peptidoglycan glycosyltransferase activity K03588,K05364,K05837 GO:0002682,GO:0002684,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136 - 8.278e-245 799.0
HFD3_k127_6315181_2 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000002886 283.0
HFD3_k127_6315181_3 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000008108 250.0
HFD3_k127_6315181_4 histone H2A K63-linked ubiquitination K01768,K03220,K10914 - 4.6.1.1 0.0000000000000000000000000000000000000004223 162.0
HFD3_k127_6315181_5 histone H2A K63-linked ubiquitination K02283 - - 0.00000000000000000000000657 111.0
HFD3_k127_6315181_6 Alpha beta hydrolase - - - 0.000000000000000008678 93.0
HFD3_k127_6315181_7 FHA domain containing protein - GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363 - 0.0000000006281 69.0
HFD3_k127_6324039_0 FtsX-like permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 468.0
HFD3_k127_6324039_1 Protein kinase domain K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000001327 239.0
HFD3_k127_6324039_2 tRNA methyltransferase complex GCD14 subunit - - - 0.000000000000000000000000000000000000000000000000004645 190.0
HFD3_k127_6324039_3 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000000002735 145.0
HFD3_k127_6324039_4 COG1404 Subtilisin-like serine proteases K12685,K20754 - 3.4.21.111 0.00000000000000006068 97.0
HFD3_k127_6324039_5 Conserved repeat domain - - - 0.00000000009749 77.0
HFD3_k127_6324039_6 exo-alpha-(2->6)-sialidase activity - - - 0.000007603 61.0
HFD3_k127_6335815_0 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000001674 202.0
HFD3_k127_6335815_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000006383 59.0
HFD3_k127_6341098_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 1.238e-274 863.0
HFD3_k127_6341098_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01466 GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005708 465.0
HFD3_k127_6341098_2 Putative neutral zinc metallopeptidase K07054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000184 283.0
HFD3_k127_6341098_3 xanthine dehydrogenase activity K13479 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000034 216.0
HFD3_k127_6341098_4 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000318 189.0
HFD3_k127_6341098_5 Trypsin - - - 0.00000000000000000000000000000000000000006724 157.0
HFD3_k127_6351676_0 GtrA-like protein K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000003997 190.0
HFD3_k127_6351676_1 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000003703 198.0
HFD3_k127_6351676_2 O-methyltransferase activity K05303 - - 0.00000000000000000000000000000000000000006866 160.0
HFD3_k127_6351676_3 phosphinothricin N-acetyltransferase activity - - - 0.000000000000000000000000000001464 134.0
HFD3_k127_6351676_4 Glycosyl transferases group 1 - - - 0.000000000000000000005031 106.0
HFD3_k127_6351676_5 Methionine biosynthesis protein MetW - - - 0.00000000000000008151 92.0
HFD3_k127_6351676_6 Yqey-like protein K09117 - - 0.0001548 46.0
HFD3_k127_6357454_0 Two component regulator propeller - - - 3.066e-208 697.0
HFD3_k127_6357454_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 377.0
HFD3_k127_6357454_2 protein kinase activity K01972,K02342,K04096 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 2.7.7.7,6.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007171 360.0
HFD3_k127_6357454_3 Methyltransferase FkbM - - - 0.00000000000000000000000000000000000000000000003122 180.0
HFD3_k127_6357454_4 NmrA-like family K19267 - 1.6.5.2 0.000000000000000000000000000000000000000352 151.0
HFD3_k127_6357454_5 - - - - 0.0000000000000000000000000000000000001102 163.0
HFD3_k127_6357454_6 N-acetyltransferase - - - 0.000000000000001139 90.0
HFD3_k127_6357454_7 transport - - - 0.00003704 57.0
HFD3_k127_6357454_8 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) - - - 0.00004721 48.0
HFD3_k127_635810_0 ADP-ribosylglycohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 406.0
HFD3_k127_635810_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006234 393.0
HFD3_k127_635810_10 - - - - 0.00002135 48.0
HFD3_k127_635810_2 PFAM Disulphide bond formation protein DsbB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006797 273.0
HFD3_k127_635810_3 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000000000000000000000000000000000001253 245.0
HFD3_k127_635810_4 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000005387 226.0
HFD3_k127_635810_5 WYL domain K13572 - - 0.000000000000000000000000000000000000000002962 170.0
HFD3_k127_635810_6 Transposase - - - 0.000000000000000000000000001509 121.0
HFD3_k127_635810_7 Hemerythrin hhe cation binding - - - 0.000000000000000000000001402 115.0
HFD3_k127_635810_8 Tetratricopeptide repeat - - - 0.0000000000000000000001249 110.0
HFD3_k127_635810_9 - - - - 0.000001673 58.0
HFD3_k127_6359528_0 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 436.0
HFD3_k127_6359528_1 Mechanosensitive ion channel K22044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000138 273.0
HFD3_k127_6359528_2 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000006346 258.0
HFD3_k127_6359528_3 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000002217 230.0
HFD3_k127_6359528_4 Uracil phosphoribosyltransferase K00761 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000009846 205.0
HFD3_k127_6359528_5 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000004428 197.0
HFD3_k127_6359528_6 ribose 5-phosphate isomerase B K01808 - 5.3.1.6 0.000000000000000000000000000000001835 141.0
HFD3_k127_6371905_0 lysine biosynthetic process via aminoadipic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 627.0
HFD3_k127_6371905_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005921 595.0
HFD3_k127_6371905_10 GDP-mannose mannosyl hydrolase activity K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000001783 196.0
HFD3_k127_6371905_11 Belongs to the GcvT family K06980 - - 0.0000000000000000000000000000000000000000000000000002442 200.0
HFD3_k127_6371905_12 peptide deformylase activity K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.00000000000000000000000000000000000000000000000001107 192.0
HFD3_k127_6371905_13 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000000003416 184.0
HFD3_k127_6371905_14 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000006335 182.0
HFD3_k127_6371905_15 Winged helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000228 158.0
HFD3_k127_6371905_16 - - - - 0.000000000000000000000000000000000001064 147.0
HFD3_k127_6371905_17 PFAM thioesterase superfamily protein K07107 - - 0.000000000000000000000000003337 118.0
HFD3_k127_6371905_18 nUDIX hydrolase K03574,K03575 - 3.6.1.55 0.0000000000000000000000001041 120.0
HFD3_k127_6371905_19 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.000002715 56.0
HFD3_k127_6371905_2 PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K01635 - 4.1.2.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 490.0
HFD3_k127_6371905_3 Permease family K06901 GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006863,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015205,GO:0015207,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0015851,GO:0015853,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:0098655,GO:0098660,GO:0098662,GO:1902600,GO:1904823 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 468.0
HFD3_k127_6371905_4 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 387.0
HFD3_k127_6371905_5 FES K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008784 273.0
HFD3_k127_6371905_6 Squalene/phytoene synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001796 256.0
HFD3_k127_6371905_7 Rhodanese-like domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000002786 233.0
HFD3_k127_6371905_8 Squalene synthase HpnD K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000257 221.0
HFD3_k127_6371905_9 squalene-associated FAD-dependent desaturase - - - 0.00000000000000000000000000000000000000000000000000000000001526 225.0
HFD3_k127_6378565_0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 315.0
HFD3_k127_6378565_1 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000007226 139.0
HFD3_k127_6378565_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000001987 65.0
HFD3_k127_6379545_0 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 463.0
HFD3_k127_6379545_1 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004441 278.0
HFD3_k127_6380727_0 PFAM peptidase M16 domain protein K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004665 273.0
HFD3_k127_6380727_1 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000003959 129.0
HFD3_k127_6387086_0 PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein K01739,K01761 - 2.5.1.48,4.4.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 435.0
HFD3_k127_6387086_1 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 317.0
HFD3_k127_6387086_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000151 276.0
HFD3_k127_6387086_3 TRAP transporter T-component - - - 0.0000000000000000000000000000000000000000000000000000000000003781 224.0
HFD3_k127_6387086_5 Belongs to the aspartokinase family K00928 GO:0003674,GO:0003824,GO:0004072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0044237 2.7.2.4 0.000000000000000007927 89.0
HFD3_k127_6387086_6 Calcineurin-like phosphoesterase - - - 0.0000000000000000564 89.0
HFD3_k127_6387086_7 Stress-responsive transcriptional regulator - - - 0.000000000000005759 76.0
HFD3_k127_6387086_8 antisigma factor binding - - - 0.0000000000003793 78.0
HFD3_k127_6387086_9 non supervised orthologous group - - - 0.0000000006767 71.0
HFD3_k127_6389546_0 Protein of unknown function DUF116 - - - 1.42e-221 700.0
HFD3_k127_6389546_1 Squalene-hopene cyclase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006117 585.0
HFD3_k127_6389546_2 enzyme of the MoaA nifB pqqE family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 535.0
HFD3_k127_6389546_3 SRP54-type protein, GTPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009087 379.0
HFD3_k127_6389546_4 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002861 286.0
HFD3_k127_6389546_5 Glycine cleavage H-protein - - - 0.00000000000000000000000000000000000000000757 164.0
HFD3_k127_6389546_6 - - - - 0.00000000000000000000000000002562 124.0
HFD3_k127_6389546_7 beta-subunit of geranylgeranyltransferase or farnesyltransferase K05956 - 2.5.1.60 0.0000000000000000000001124 108.0
HFD3_k127_6389546_8 Bacterial PH domain K08981 - - 0.000000000000000000007964 101.0
HFD3_k127_639635_0 MacB-like periplasmic core domain - - - 2.124e-263 834.0
HFD3_k127_639635_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005166 366.0
HFD3_k127_639635_2 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 323.0
HFD3_k127_639635_3 dehydrogenases and related proteins - - - 0.0000000000000000000000000000000000000005429 162.0
HFD3_k127_639635_4 methyltransferase - - - 0.000000000000000000000000000000000001293 147.0
HFD3_k127_639635_5 creatininase K01470 - 3.5.2.10 0.000000000000000000000000000000000002354 155.0
HFD3_k127_6397145_0 Phosphoesterase family - - - 2.896e-220 712.0
HFD3_k127_6397145_1 PFAM chemotaxis sensory transducer K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 544.0
HFD3_k127_6458944_0 Pfam L-fucose isomerase, C-terminal domain - - - 5.43e-215 676.0
HFD3_k127_6458944_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 551.0
HFD3_k127_6458944_2 Carbon-nitrogen hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 405.0
HFD3_k127_6458944_3 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 302.0
HFD3_k127_6458944_4 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000001448 237.0
HFD3_k127_6458944_5 YqcI/YcgG family - - - 0.00000000000000000000000000000000000000000000000000000001503 205.0
HFD3_k127_6458944_6 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.000000000000000000000000000000000000000000000003327 180.0
HFD3_k127_6458944_7 Glycosyl hydrolases family 43 K01198 - 3.2.1.37 0.00000000000000000000000000000000000000003718 162.0
HFD3_k127_6458944_8 Transcriptional regulator - - - 0.0000000000000000000000000000000000001334 154.0
HFD3_k127_6458944_9 - - - - 0.0000000000000000000002022 106.0
HFD3_k127_6462474_0 Dehydrogenase E1 component K11381 - 1.2.4.4 7.285e-236 743.0
HFD3_k127_6462474_1 Gas vesicle protein K - - - 0.0000000000000000000000005868 111.0
HFD3_k127_6462474_2 Gas vesicle synthesis protein GvpL/GvpF - - - 0.000000001202 69.0
HFD3_k127_6478711_0 membrane K07027,K14205 - 2.3.2.3 2.188e-257 818.0
HFD3_k127_6478711_1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001304 262.0
HFD3_k127_6478711_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008566 261.0
HFD3_k127_6478711_3 Protein of unknown function (DUF421) - - - 0.0000004888 58.0
HFD3_k127_6484156_0 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000003811 209.0
HFD3_k127_6484156_1 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.2.1.113 0.000000000001315 69.0
HFD3_k127_64933_0 Tricorn protease homolog - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 608.0
HFD3_k127_64933_1 amino acid carrier protein K03310 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 478.0
HFD3_k127_64933_10 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.0000000000000000000000000000000000000000002164 162.0
HFD3_k127_64933_11 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000004698 143.0
HFD3_k127_64933_12 PFAM HNH endonuclease - - - 0.00000000000000000000000000000005966 132.0
HFD3_k127_64933_13 - - - - 0.000000000000000000000000005546 120.0
HFD3_k127_64933_14 PFAM RNP-1 like RNA-binding protein - - - 0.000000000000000000000000007842 113.0
HFD3_k127_64933_15 CoA binding domain - - - 0.00000000000000001923 90.0
HFD3_k127_64933_17 LTXXQ motif family protein - - - 0.000001382 56.0
HFD3_k127_64933_18 Domain of unknown function (DUF4349) - - - 0.0007364 48.0
HFD3_k127_64933_2 PFAM Cation K03498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004354 449.0
HFD3_k127_64933_3 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 416.0
HFD3_k127_64933_4 COG0569 K transport systems NAD-binding component K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000877 332.0
HFD3_k127_64933_5 Histidine-specific methyltransferase, SAM-dependent K18911 - 2.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 326.0
HFD3_k127_64933_6 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 291.0
HFD3_k127_64933_7 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001705 284.0
HFD3_k127_64933_8 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000001711 256.0
HFD3_k127_64933_9 WYL domain - - - 0.0000000000000000000000000000000000000000000006276 178.0
HFD3_k127_6501267_0 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006287 414.0
HFD3_k127_6501267_1 Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005312 384.0
HFD3_k127_6501267_2 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000001416 224.0
HFD3_k127_6521199_0 Glycosyl hydrolases family 2 - - - 0.0 1028.0
HFD3_k127_6521199_1 ASPIC and UnbV - - - 9.788e-215 681.0
HFD3_k127_6521199_10 Lipase (class 3) - - - 0.000000000000000000000000000000000000009719 157.0
HFD3_k127_6521199_11 - - - - 0.0000000000000000000000000000000001499 135.0
HFD3_k127_6521199_12 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000002019 138.0
HFD3_k127_6521199_13 Ankyrin repeats (many copies) - - - 0.000000000000000000000000002113 125.0
HFD3_k127_6521199_14 - - - - 0.00000000000000000000105 101.0
HFD3_k127_6521199_2 PFAM Cytochrome c, bacterial - - - 2.588e-202 642.0
HFD3_k127_6521199_3 Glycosyl hydrolase family 10 K01181 - 3.2.1.8 1.188e-194 637.0
HFD3_k127_6521199_4 PFAM Trehalose utilisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 391.0
HFD3_k127_6521199_5 PFAM cytochrome B561 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001335 289.0
HFD3_k127_6521199_6 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001673 281.0
HFD3_k127_6521199_7 Transcriptional regulator, LysR - - - 0.0000000000000000000000000000000000000000000000000000000000005387 226.0
HFD3_k127_6521199_8 - K07112 - - 0.000000000000000000000000000000000000000000000003515 184.0
HFD3_k127_6521199_9 TPR repeat - - - 0.000000000000000000000000000000000000002023 165.0
HFD3_k127_6549692_0 Aminotransferase K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 556.0
HFD3_k127_6549692_1 phosphoenolpyruvate carboxykinase (ATP) activity K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 301.0
HFD3_k127_6549692_2 - - - - 0.000000000000000000000000000000000000000000000003939 190.0
HFD3_k127_6549692_3 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000001943 133.0
HFD3_k127_6549692_4 serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.000007049 49.0
HFD3_k127_6585610_0 Belongs to the argininosuccinate synthase family. Type K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 4.948e-241 749.0
HFD3_k127_6585610_1 D-aminoacylase domain protein K01465,K06015 - 3.5.1.81,3.5.2.3 3.892e-206 655.0
HFD3_k127_6585610_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000003559 236.0
HFD3_k127_6585610_3 efflux transmembrane transporter activity - - - 0.000000000000000000000000000002643 131.0
HFD3_k127_6585610_4 Catalyzes the reduction of the disulfide bonds in the heme binding site of apocytochrome c - GO:0008150,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840 - 0.0000000000000000009826 99.0
HFD3_k127_6585610_5 serine protease - - - 0.0000000000003022 79.0
HFD3_k127_6585610_7 SnoaL-like polyketide cyclase - - - 0.0002651 49.0
HFD3_k127_6598338_0 PAS domain containing protein K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001821 264.0
HFD3_k127_6598338_1 CheB methylesterase - - - 0.00000000000000000000000000000000003211 141.0
HFD3_k127_6598338_2 PFAM Response regulator receiver domain - - - 0.00000000000003252 81.0
HFD3_k127_6598338_3 Tetratricopeptide repeats - - - 0.000001375 62.0
HFD3_k127_6599206_0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) K01214 - 3.2.1.68 5.465e-305 962.0
HFD3_k127_6599206_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.858e-247 775.0
HFD3_k127_6599206_2 Domain of unknown function (DUF3416) K16147 - 2.4.99.16 3.329e-224 714.0
HFD3_k127_6599206_3 peptidyl-lysine modification to peptidyl-hypusine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000382 341.0
HFD3_k127_6599206_4 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 320.0
HFD3_k127_6599206_5 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002973 306.0
HFD3_k127_6599206_6 alpha amylase catalytic K05343 - 3.2.1.1,5.4.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004052 300.0
HFD3_k127_6599206_7 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000001258 279.0
HFD3_k127_6599206_8 Domain of unknown function (DUF4112) - - - 0.000000000000000000000001134 111.0
HFD3_k127_6599206_9 Protein of unknown function (DUF3365) - - - 0.0000000000000000000001151 112.0
HFD3_k127_6635053_0 Multicopper oxidase K08100 - 1.3.3.5 0.0 1063.0
HFD3_k127_6635053_1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 1.856e-281 886.0
HFD3_k127_6635053_2 Zn-dependent protease with chaperone function K03799,K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009483 415.0
HFD3_k127_6635053_3 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 367.0
HFD3_k127_6635053_4 Dienelactone hydrolase family K06999 - - 0.000000000000000000000000000000000000000000000000000000000000000000006403 239.0
HFD3_k127_6635053_5 NADPH-dependent F420 reductase K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000003044 218.0
HFD3_k127_6635053_6 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000000000000001064 215.0
HFD3_k127_6635053_7 lipoprotein biosynthetic process K13292 - - 0.00000000000000000000000000000000000000002244 166.0
HFD3_k127_6635053_8 oxidoreductase activity - - - 0.000000000000000000000000000000003393 137.0
HFD3_k127_6635053_9 Histidine kinase - - - 0.000003662 56.0
HFD3_k127_6636725_0 Threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004437 476.0
HFD3_k127_6636725_1 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000002534 269.0
HFD3_k127_6636725_2 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000001872 266.0
HFD3_k127_6636725_3 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000001272 175.0
HFD3_k127_6652093_0 ABC transporter K03701 - - 3.037e-297 930.0
HFD3_k127_6652093_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 3.5e-286 900.0
HFD3_k127_6652093_10 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009247 288.0
HFD3_k127_6652093_11 Phage integrase, N-terminal SAM-like domain K03733,K04763 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001645 279.0
HFD3_k127_6652093_12 DNA processing protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009527 269.0
HFD3_k127_6652093_13 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009151 254.0
HFD3_k127_6652093_14 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001409 260.0
HFD3_k127_6652093_15 PFAM Response regulator receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006265 262.0
HFD3_k127_6652093_16 HNH nucleases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005743 243.0
HFD3_k127_6652093_17 Belongs to the peptidase S8 family K17734 - - 0.000000000000000000000000000000000000000000000000000000000000000000002093 261.0
HFD3_k127_6652093_18 Belongs to the DapA family K01714,K22397 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016830,GO:0016832,GO:0019520,GO:0019752,GO:0032787,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046395,GO:0047440,GO:0071704,GO:0072329,GO:1901575 4.1.2.28,4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000002296 237.0
HFD3_k127_6652093_19 Belongs to the peptidase S8 family K17734 - - 0.00000000000000000000000000000000000000000000000000000000000000004682 244.0
HFD3_k127_6652093_2 PFAM amino acid permease-associated region - - - 7.947e-216 680.0
HFD3_k127_6652093_20 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000002894 229.0
HFD3_k127_6652093_21 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000001418 200.0
HFD3_k127_6652093_22 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000003676 195.0
HFD3_k127_6652093_23 RNA polymerase sigma factor K03088 - - 0.0000000000000000000000000000000000000000009792 164.0
HFD3_k127_6652093_24 ABC-type dipeptide oligopeptide nickel transport K00759,K02033 - 2.4.2.7 0.0000000000000000000000000000000000000000165 166.0
HFD3_k127_6652093_25 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000602 152.0
HFD3_k127_6652093_26 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.0000000000000000000000000000000000006709 147.0
HFD3_k127_6652093_27 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.000000000000000000000000000000006094 130.0
HFD3_k127_6652093_28 Thymidylate kinase K00943 GO:0003674,GO:0003824,GO:0004550,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006139,GO:0006165,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000006889 129.0
HFD3_k127_6652093_29 NLP P60 protein - - - 0.0000000000000000000000000008978 119.0
HFD3_k127_6652093_3 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 522.0
HFD3_k127_6652093_30 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K00969,K09710 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 2.7.7.18 0.000000000000000000000000001928 117.0
HFD3_k127_6652093_31 radical SAM domain protein - - - 0.00000000000000000000001251 115.0
HFD3_k127_6652093_32 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000207 91.0
HFD3_k127_6652093_33 - - - - 0.0000000000007395 78.0
HFD3_k127_6652093_34 Alanine acetyltransferase K03790 - 2.3.1.128 0.000000000001548 76.0
HFD3_k127_6652093_35 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000001427 65.0
HFD3_k127_6652093_36 TIGRFAM amino acid adenylation domain - - - 0.00000002068 66.0
HFD3_k127_6652093_37 Tetratricopeptide repeat - - - 0.000000548 58.0
HFD3_k127_6652093_4 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 374.0
HFD3_k127_6652093_5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 368.0
HFD3_k127_6652093_6 aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005788 351.0
HFD3_k127_6652093_7 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006247 325.0
HFD3_k127_6652093_8 extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 337.0
HFD3_k127_6652093_9 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 318.0
HFD3_k127_6671002_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 443.0
HFD3_k127_6671002_1 Belongs to the peptidase M16 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 436.0
HFD3_k127_6671002_2 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 399.0
HFD3_k127_6671002_3 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000049,GO:0000154,GO:0001510,GO:0002935,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016426,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070040,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:0140102,GO:1901360,GO:1901363 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 345.0
HFD3_k127_6671002_4 MiaB-like tRNA modifying enzyme K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000008262 284.0
HFD3_k127_6671002_5 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000002668 192.0
HFD3_k127_6671275_0 Amidohydrolase family K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007143 513.0
HFD3_k127_6671275_1 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001216 288.0
HFD3_k127_6671275_2 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.000000000000000000000000000000000000000000000000002323 184.0
HFD3_k127_6686393_0 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007513 499.0
HFD3_k127_6686393_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008766 490.0
HFD3_k127_6686393_10 Putative adhesin - - - 0.0003097 51.0
HFD3_k127_6686393_2 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004971 400.0
HFD3_k127_6686393_3 Surface antigen K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009491 266.0
HFD3_k127_6686393_4 Pyridoxal-phosphate dependent enzyme K01751 - 4.3.1.15 0.0000000000000000000000000000000000000000000000000000001036 212.0
HFD3_k127_6686393_5 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000006978 149.0
HFD3_k127_6686393_6 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000002056 120.0
HFD3_k127_6686393_7 chlorophyll binding K03640 - - 0.000000000000000000000001018 111.0
HFD3_k127_6686393_8 TIGRFAM TonB family K03832 - - 0.0000000000000000000007816 106.0
HFD3_k127_6686393_9 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000000000000009157 113.0
HFD3_k127_6689460_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006742 518.0
HFD3_k127_6689460_1 PFAM glycosyl transferase family 51 K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000087 407.0
HFD3_k127_6689460_2 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000002104 205.0
HFD3_k127_6689460_3 phosphatidylcholine synthase K01004 - 2.7.8.24 0.0000000000000000000000000000000000000000000000000000002434 202.0
HFD3_k127_6689460_4 DEAD DEAH box K03724 - - 0.0000000000000000000000000003659 114.0
HFD3_k127_6689460_5 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.00001219 52.0
HFD3_k127_670518_0 cAMP biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003295 288.0
HFD3_k127_670518_1 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.00000002176 67.0
HFD3_k127_6712669_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 401.0
HFD3_k127_6712669_1 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000001698 117.0
HFD3_k127_6712669_2 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000003724 119.0
HFD3_k127_6740715_0 histidine kinase HAMP region domain protein K13598 - 2.7.13.3 0.00000000000000000000000000000000000000000000000002527 197.0
HFD3_k127_6740715_1 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000001458 183.0
HFD3_k127_6740715_2 Domain of unknown function (DUF4390) - - - 0.0002828 52.0
HFD3_k127_6753884_0 Zinc carboxypeptidase - - - 1.982e-312 989.0
HFD3_k127_6753884_1 PFAM peptidase - - - 5.114e-209 662.0
HFD3_k127_6753884_2 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008667 589.0
HFD3_k127_6753884_3 TRAP transporter solute receptor, TAXI family K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 300.0
HFD3_k127_6753884_4 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005403 246.0
HFD3_k127_6753884_5 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001663 239.0
HFD3_k127_6825177_0 Oxidoreductase - - - 1.972e-277 862.0
HFD3_k127_6825177_1 peptidase S9A, prolyl oligopeptidase domain protein beta-propeller K01354 - 3.4.21.83 7.366e-250 793.0
HFD3_k127_6825177_10 - - - - 0.00000000000006001 80.0
HFD3_k127_6825177_11 PFAM Endonuclease Exonuclease phosphatase - - - 0.0000000000001196 81.0
HFD3_k127_6825177_12 COG2133 Glucose sorbosone dehydrogenases K21430 - - 0.00005494 51.0
HFD3_k127_6825177_2 Prolyl oligopeptidase family - - - 2.518e-243 781.0
HFD3_k127_6825177_3 Dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 456.0
HFD3_k127_6825177_4 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006491 419.0
HFD3_k127_6825177_5 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000001396 225.0
HFD3_k127_6825177_6 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000000000000000005458 225.0
HFD3_k127_6825177_8 Gluconate 2-dehydrogenase subunit 3 - - - 0.000000000000000000000000000000000000000001762 176.0
HFD3_k127_6825177_9 TIR domain - - - 0.00000000000000000000000000005001 124.0
HFD3_k127_6829362_0 PFAM tRNA synthetase, class II (D, K and N) K01893 - 6.1.1.22 1.144e-194 629.0
HFD3_k127_6829362_1 Carbohydrate phosphorylase K00688 - 2.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005088 363.0
HFD3_k127_6829362_10 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000008561 129.0
HFD3_k127_6829362_11 CYTH K05873 - 4.6.1.1 0.0000000000000000003956 99.0
HFD3_k127_6829362_13 TM2 domain - - - 0.000000003743 64.0
HFD3_k127_6829362_2 Metallopeptidase family M24 K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 362.0
HFD3_k127_6829362_3 serine-type endopeptidase activity K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003523 319.0
HFD3_k127_6829362_4 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006915 246.0
HFD3_k127_6829362_5 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000156 249.0
HFD3_k127_6829362_6 phosphotransferase related to Ser Thr protein kinases K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000009213 236.0
HFD3_k127_6829362_7 - - - - 0.00000000000000000000000000000000000000000000000000000005504 206.0
HFD3_k127_6829362_8 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000007109 165.0
HFD3_k127_6829362_9 Catalyzes the formation of UDP-glucose, from UTP and glucose 1-phosphate K00966,K16881 GO:0000166,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0003983,GO:0005488,GO:0006011,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009225,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0051748,GO:0055086,GO:0070569,GO:0071704,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363 2.7.7.13,5.4.2.8 0.00000000000000000000000000000001092 143.0
HFD3_k127_689796_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169,K03737 - 1.2.7.1 0.0 1371.0
HFD3_k127_6940486_0 Tricorn protease PDZ domain K08676 - - 0.0 1187.0
HFD3_k127_6940486_1 Chase2 domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 371.0
HFD3_k127_6940486_2 methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000005686 205.0
HFD3_k127_6940486_3 Belongs to the ompA family - - - 0.000000000000000000000000000006219 132.0
HFD3_k127_6940486_4 FecR protein - - - 0.00000000000000000000000009327 113.0
HFD3_k127_6940486_5 AsmA family K07289 - - 0.000000005983 69.0
HFD3_k127_6940486_6 - - - - 0.00000006083 65.0
HFD3_k127_6998411_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 1.146e-199 650.0
HFD3_k127_6998411_1 Belongs to the glycosyl hydrolase family 6 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005079 518.0
HFD3_k127_6998411_2 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 456.0
HFD3_k127_6998411_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006218 387.0
HFD3_k127_6998411_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348 347.0
HFD3_k127_6998411_5 PFAM RNA binding S1 domain protein K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001249 284.0
HFD3_k127_6998411_6 Chitinase class I K03791 - - 0.0000000000000000000000000000000000000000000000000009356 192.0
HFD3_k127_6998411_7 Protein kinase domain - - - 0.000000000000000000000000000000000000000000000002878 178.0
HFD3_k127_6998411_8 Dimethlysulfonioproprionate lyase - - - 0.0000000000000000000000000000000000000000000001518 172.0
HFD3_k127_6998411_9 Belongs to the ompA family K03640 - - 0.00002449 54.0
HFD3_k127_6998802_0 Belongs to the GSP D family K02280 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007639 306.0
HFD3_k127_6998802_1 PFAM SAF domain K02279 - - 0.00000000000000000000000000000000000000000002329 172.0
HFD3_k127_6998802_2 Putative Flp pilus-assembly TadE/G-like - - - 0.000000000000000000000000000000000000114 158.0
HFD3_k127_6998802_3 PFAM Peptidase A24A, prepilin type IV K02278 - 3.4.23.43 0.00000000000002666 79.0
HFD3_k127_6998802_4 TadE-like protein - - - 0.0000004994 61.0
HFD3_k127_6998802_5 Flp Fap pilin component K02651 - - 0.00003033 53.0
HFD3_k127_6998802_6 AAA domain K02282 - - 0.0001577 49.0
HFD3_k127_7000470_0 Threonine synthase K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 452.0
HFD3_k127_7000470_1 Mur ligase middle domain K02558 - 6.3.2.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006739 447.0
HFD3_k127_7000470_10 TIGRFAM urea amidolyase related protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005615 259.0
HFD3_k127_7000470_11 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000005434 245.0
HFD3_k127_7000470_12 Secretin and TonB N terminus short domain K02666 - - 0.000000000000000000000000000000000000000000000000000000000000001423 244.0
HFD3_k127_7000470_13 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000004008 213.0
HFD3_k127_7000470_14 LD-carboxypeptidase K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000000004157 217.0
HFD3_k127_7000470_15 5-oxoprolinase (ATP-hydrolyzing) activity K01457,K06351,K07160 - 3.5.1.54 0.00000000000000000000000000000000000000000000000000003257 205.0
HFD3_k127_7000470_16 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000003497 201.0
HFD3_k127_7000470_17 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000002186 181.0
HFD3_k127_7000470_18 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000002004 171.0
HFD3_k127_7000470_19 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.0000000000000000000000004736 117.0
HFD3_k127_7000470_2 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000514 424.0
HFD3_k127_7000470_20 PFAM Pilus assembly protein PilO K02664 - - 0.0000000000000000009583 96.0
HFD3_k127_7000470_21 cell adhesion involved in biofilm formation K02453 - - 0.000000000001385 82.0
HFD3_k127_7000470_22 SNARE associated Golgi protein - - - 0.00000003584 60.0
HFD3_k127_7000470_23 Fimbrial assembly protein (PilN) K02663 - - 0.0000002161 64.0
HFD3_k127_7000470_3 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 341.0
HFD3_k127_7000470_4 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008357 336.0
HFD3_k127_7000470_5 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004237 318.0
HFD3_k127_7000470_6 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005569 320.0
HFD3_k127_7000470_7 Type ii and iii secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 315.0
HFD3_k127_7000470_8 Helix-hairpin-helix domain K02347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 304.0
HFD3_k127_7000470_9 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006202 296.0
HFD3_k127_7012759_0 repeat protein - - - 6.533e-213 687.0
HFD3_k127_7012759_1 SMART Elongator protein 3 MiaB NifB - - - 3.196e-212 668.0
HFD3_k127_7012759_2 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000007902 205.0
HFD3_k127_7012759_3 Domain of unknown function (DUF305) - - - 0.0000000000000000000000000000000000000000002926 181.0
HFD3_k127_7041461_0 transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 447.0
HFD3_k127_7041461_1 Xylose isomerase domain protein TIM barrel - - - 0.00000000000000000000000006148 114.0
HFD3_k127_7041461_2 Xylose isomerase domain protein TIM barrel - - - 0.00000000000000000001414 105.0
HFD3_k127_7043747_0 Zinc carboxypeptidase - - - 0.0 1320.0
HFD3_k127_7043747_1 Ribonuclease, BN K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000002126 243.0
HFD3_k127_7043747_2 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.00000000000000000000000000000000000000000000001314 182.0
HFD3_k127_7100417_0 Hypothetical glycosyl hydrolase 6 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007191 542.0
HFD3_k127_7100417_1 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 436.0
HFD3_k127_7109101_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 529.0
HFD3_k127_7109101_1 Belongs to the peptidase M16 family K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 335.0
HFD3_k127_7109101_10 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000003325 110.0
HFD3_k127_7109101_11 translation initiation factor activity K03239,K03680 - - 0.00000000000000001821 89.0
HFD3_k127_7109101_12 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.3.5.6,6.3.5.7 0.0000000000000002768 83.0
HFD3_k127_7109101_14 Insulinase (Peptidase family M16) - - - 0.0004723 52.0
HFD3_k127_7109101_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005669 322.0
HFD3_k127_7109101_3 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007424 318.0
HFD3_k127_7109101_4 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000000008422 195.0
HFD3_k127_7109101_5 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000002801 166.0
HFD3_k127_7109101_6 Hsp20/alpha crystallin family K13993 - - 0.000000000000000000000000000000000000002692 151.0
HFD3_k127_7109101_7 S1 P1 Nuclease - - - 0.0000000000000000000000000000000000005885 159.0
HFD3_k127_7109101_8 PFAM AMMECR1 domain protein K09141 - - 0.0000000000000000000000000000000000009883 147.0
HFD3_k127_7109101_9 MgtC family K07507 - - 0.000000000000000000000000000002808 129.0
HFD3_k127_7110837_0 COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007241 543.0
HFD3_k127_7110837_1 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004771 277.0
HFD3_k127_7110837_2 Rhodanese-like domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000001377 172.0
HFD3_k127_7143677_0 MacB-like periplasmic core domain - - - 1.955e-211 683.0
HFD3_k127_7143677_1 FAD dependent oxidoreductase - - - 7.426e-204 648.0
HFD3_k127_7143677_2 myo-inosose-2 dehydratase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 401.0
HFD3_k127_7143677_3 TIGRFAM VWFA-related Acidobacterial domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 302.0
HFD3_k127_7143677_4 TIGRFAM VWFA-related Acidobacterial domain - - - 0.0000000000000000000000000000000000000000000000004884 184.0
HFD3_k127_7145981_0 PFAM UDP-glucose GDP-mannose dehydrogenase family, NAD binding domain K02472,K13015 - 1.1.1.136,1.1.1.336 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007957 600.0
HFD3_k127_7145981_1 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 350.0
HFD3_k127_7145981_2 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000001083 113.0
HFD3_k127_7145981_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01991 - - 0.0000000000000000168 89.0
HFD3_k127_7145981_4 PFAM Uncharacterised protein family (UPF0227) K07000 - - 0.00002533 48.0
HFD3_k127_7145981_5 diguanylate cyclase - - - 0.0001157 51.0
HFD3_k127_7155897_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 1.568e-272 847.0
HFD3_k127_7155897_1 ATP-dependent helicase K03579 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000009069 268.0
HFD3_k127_7155897_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07025 - - 0.000000000000000000000000000000000001675 157.0
HFD3_k127_7168828_0 AAA ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000432 219.0
HFD3_k127_7168828_1 COG3209 Rhs family protein - - - 0.00000000000000000000000000000000000000000000000000000008948 211.0
HFD3_k127_7185385_0 Dienelactone hydrolase family K01278 - 3.4.14.5 0.0 1042.0
HFD3_k127_7185385_1 Dienelactone hydrolase family - - - 1.579e-230 732.0
HFD3_k127_7185385_10 Regulates arginine biosynthesis genes K03402 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.000000000000000000000003245 108.0
HFD3_k127_7185385_11 Catalyzes the formation of N-acetyl-L-glutamate from acetyl-CoA and L-glutamate K00619 - 2.3.1.1 0.000000000000000000003892 107.0
HFD3_k127_7185385_13 Histidine phosphatase superfamily (branch 1) K08296 - - 0.0000000000000002337 84.0
HFD3_k127_7185385_2 COG1228 Imidazolonepropionase and related K01443 - 3.5.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006012 527.0
HFD3_k127_7185385_3 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 465.0
HFD3_k127_7185385_4 TIGRFAM argininosuccinate lyase K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 387.0
HFD3_k127_7185385_5 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 367.0
HFD3_k127_7185385_6 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008925 347.0
HFD3_k127_7185385_7 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000006042 285.0
HFD3_k127_7185385_8 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000002778 255.0
HFD3_k127_7185385_9 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000007099 147.0
HFD3_k127_7196937_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 439.0
HFD3_k127_7196937_1 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001007 245.0
HFD3_k127_7196937_2 domain protein - - - 0.0000000000000000000000000005438 131.0
HFD3_k127_7196937_3 aminopeptidase activity - - - 0.00000000002023 65.0
HFD3_k127_7209372_0 Molydopterin dinucleotide binding domain K08352 - 1.8.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 439.0
HFD3_k127_7209372_1 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003966 311.0
HFD3_k127_7209372_2 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000002284 219.0
HFD3_k127_7209372_3 Polysulphide reductase K00185 - - 0.0000000000000000000000000000000000001539 158.0
HFD3_k127_7209372_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000001676 142.0
HFD3_k127_7209372_5 4Fe-4S dicluster domain K00184 - - 0.000000000004374 66.0
HFD3_k127_7209372_6 PFAM Cyclic nucleotide-binding domain - - - 0.000000000504 67.0
HFD3_k127_7209372_7 Cytochrome c7 and related cytochrome c - - - 0.000000002328 70.0
HFD3_k127_7212800_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004659 622.0
HFD3_k127_7212800_1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K00333 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 471.0
HFD3_k127_7212800_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.6.5.3 0.000000000000000000000000000000000000007289 147.0
HFD3_k127_7212800_11 von Willebrand factor, type A - - - 0.000000000000000000000000000000000007691 149.0
HFD3_k127_7212800_12 PFAM Cytochrome c assembly protein - - - 0.000000000000000000000000000000002129 139.0
HFD3_k127_7212800_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000000012 132.0
HFD3_k127_7212800_14 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000000000002057 112.0
HFD3_k127_7212800_15 von Willebrand factor, type A - - - 0.00000000003832 74.0
HFD3_k127_7212800_2 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009139 423.0
HFD3_k127_7212800_3 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 428.0
HFD3_k127_7212800_4 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 403.0
HFD3_k127_7212800_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 361.0
HFD3_k127_7212800_6 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 348.0
HFD3_k127_7212800_7 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000005534 261.0
HFD3_k127_7212800_8 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000001207 239.0
HFD3_k127_7212800_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000000003504 175.0
HFD3_k127_724208_0 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 499.0
HFD3_k127_724208_1 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008059 465.0
HFD3_k127_724208_10 - - - - 0.000004526 56.0
HFD3_k127_724208_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003378 348.0
HFD3_k127_724208_3 Acetamidase/Formamidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 308.0
HFD3_k127_724208_4 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004042 294.0
HFD3_k127_724208_5 Belongs to the peptidase S8 family K17734 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008245 267.0
HFD3_k127_724208_6 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000000004133 142.0
HFD3_k127_724208_7 Oxidoreductase FAD-binding domain - - - 0.0000000000000000001835 97.0
HFD3_k127_724208_8 periplasmic or secreted lipoprotein K04065 - - 0.0000002065 57.0
HFD3_k127_724208_9 - - - - 0.0000009689 59.0
HFD3_k127_7249018_0 Belongs to the glycosyl hydrolase 31 family K01187,K01811 - 3.2.1.177,3.2.1.20 2.321e-279 878.0
HFD3_k127_7249018_1 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 557.0
HFD3_k127_7249018_10 Peptidase dimerisation domain K12941 - - 0.0000000000000000000000000000000000000000000000000000001017 202.0
HFD3_k127_7249018_11 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000000000000001374 164.0
HFD3_k127_7249018_2 Molybdenum Cofactor Synthesis C K03639 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 420.0
HFD3_k127_7249018_3 Trypsin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003663 390.0
HFD3_k127_7249018_4 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007386 384.0
HFD3_k127_7249018_5 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006495 289.0
HFD3_k127_7249018_6 double-stranded DNA 3'-5' exodeoxyribonuclease activity K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002274 280.0
HFD3_k127_7249018_7 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000004029 246.0
HFD3_k127_7249018_8 Imidazolonepropionase and related - - - 0.0000000000000000000000000000000000000000000000000000000000000004343 237.0
HFD3_k127_7249018_9 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD - - - 0.00000000000000000000000000000000000000000000000000000002506 205.0
HFD3_k127_7259064_0 Por secretion system C-terminal sorting domain-containing protein - - - 2.828e-274 878.0
HFD3_k127_7259064_1 SPFH domain-Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 528.0
HFD3_k127_7259064_10 Trypsin K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030163,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051603,GO:0061077,GO:0070011,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.21.107 0.0007705 50.0
HFD3_k127_7259064_2 PFAM Acetyl-CoA hydrolase transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005597 481.0
HFD3_k127_7259064_3 tRNA wobble cytosine modification - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 447.0
HFD3_k127_7259064_4 Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 439.0
HFD3_k127_7259064_5 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 343.0
HFD3_k127_7259064_6 SelR domain K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000002242 221.0
HFD3_k127_7259064_7 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000002442 185.0
HFD3_k127_7259064_8 MacB-like periplasmic core domain - - - 0.00000006016 57.0
HFD3_k127_7259064_9 - - - - 0.0000001391 64.0
HFD3_k127_7269628_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007309 587.0
HFD3_k127_7269628_1 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008882 533.0
HFD3_k127_7269628_2 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 392.0
HFD3_k127_7269628_3 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005971 367.0
HFD3_k127_7269628_4 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001562 291.0
HFD3_k127_7269628_5 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000009109 265.0
HFD3_k127_7269628_6 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000001607 227.0
HFD3_k127_7269628_7 bacterial (prokaryotic) histone like domain K03530 - - 0.00000000000000000000000000000235 122.0
HFD3_k127_7269628_8 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00006289 46.0
HFD3_k127_7300992_0 Flavin containing amine oxidoreductase - - - 2.94e-280 867.0
HFD3_k127_7300992_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004642 545.0
HFD3_k127_7300992_2 TIGRFAM phytoene desaturase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 507.0
HFD3_k127_7300992_3 Ring hydroxylating alpha subunit (catalytic domain) K00479 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 474.0
HFD3_k127_7300992_4 Zinc carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 428.0
HFD3_k127_7300992_5 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 337.0
HFD3_k127_7300992_6 amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001726 281.0
HFD3_k127_7300992_7 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000000000000005573 146.0
HFD3_k127_7300992_8 phosphoglycerate mutase - - - 0.000000000000000000105 104.0
HFD3_k127_7300992_9 - - - - 0.00000000000006856 85.0
HFD3_k127_7331630_0 helix_turn_helix, Lux Regulon - - - 2.097e-297 940.0
HFD3_k127_7331630_1 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000008981 164.0
HFD3_k127_7331630_2 - - - - 0.00000000000000000000000003917 119.0
HFD3_k127_7331630_3 PFAM FAD linked oxidase domain protein - - - 0.000000000000000000503 89.0
HFD3_k127_7331630_4 Domain of Unknown Function (DUF1206) - - - 0.0000000000008182 74.0
HFD3_k127_7331630_5 Transposase IS116/IS110/IS902 family - - - 0.00000001443 63.0
HFD3_k127_7331630_6 transposase IS116 IS110 IS902 family protein - - - 0.0000009396 57.0
HFD3_k127_7340954_0 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 536.0
HFD3_k127_7340954_1 Bacterial PH domain K08981 - - 0.00000000000000000000000000000000000000000000000000004929 199.0
HFD3_k127_7340954_2 Probably functions as a manganese efflux pump - - - 0.0000000000000000000000000000000000000000000007212 188.0
HFD3_k127_7340954_3 C-terminal binding-module, SLH-like, of glucodextranase - - - 0.00000000000000000000005829 115.0
HFD3_k127_7340954_4 Bacterial PH domain K09167 - - 0.000000000000000000007915 98.0
HFD3_k127_7340954_5 Protein kinase domain K12132 - 2.7.11.1 0.000000000000001474 91.0
HFD3_k127_7340954_6 Choline/ethanolamine kinase K07102 - 2.7.1.221 0.0000000000002491 70.0
HFD3_k127_7340954_7 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00003703 55.0
HFD3_k127_7341341_0 arylsulfatase activity - - - 9.902e-234 742.0
HFD3_k127_7341341_1 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 544.0
HFD3_k127_7341341_2 Retinal pigment epithelial membrane protein K00464,K11159 - 1.13.11.75 0.000000000000000000000000000000000000000000000000000000000000000155 240.0
HFD3_k127_7341341_3 Halogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000005206 242.0
HFD3_k127_7341341_4 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000004021 140.0
HFD3_k127_7341341_5 DinB superfamily - - - 0.0000001142 63.0
HFD3_k127_7345015_0 Carboxypeptidase regulatory-like domain - - - 2.167e-278 893.0
HFD3_k127_7345015_1 Belongs to the glycosyl hydrolase 67 family K01235 - 3.2.1.139 1.833e-248 803.0
HFD3_k127_7345015_10 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989,K02428 - 2.7.7.56,3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 317.0
HFD3_k127_7345015_11 Endoribonuclease that initiates mRNA decay K18682 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007209 269.0
HFD3_k127_7345015_12 Transglycosylase SLT domain K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001577 299.0
HFD3_k127_7345015_13 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000002543 227.0
HFD3_k127_7345015_14 Predicted membrane protein (DUF2231) - - - 0.00000000000000000000000000000000000000000000000000000008749 201.0
HFD3_k127_7345015_15 protein kinase related protein - - - 0.0000000000000000000000000000000000000000000000002089 199.0
HFD3_k127_7345015_16 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000121 175.0
HFD3_k127_7345015_17 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000001092 166.0
HFD3_k127_7345015_18 DinB superfamily - - - 0.00000000000000000000000000002082 131.0
HFD3_k127_7345015_19 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104,K03325,K03741,K03892,K18701 - 1.20.4.1,2.8.4.2,3.1.3.48 0.00000000000000000000000007045 115.0
HFD3_k127_7345015_2 WD40-like Beta Propeller Repeat - - - 1.699e-231 750.0
HFD3_k127_7345015_20 Sporulation and spore germination - - - 0.000000000000000000004004 109.0
HFD3_k127_7345015_21 - - - - 0.00000000000000002087 85.0
HFD3_k127_7345015_22 3D domain - - - 0.00000000000002377 80.0
HFD3_k127_7345015_23 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.000000000000385 76.0
HFD3_k127_7345015_24 nuclear chromosome segregation - - - 0.000000000009389 77.0
HFD3_k127_7345015_25 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000002074 71.0
HFD3_k127_7345015_3 ABC transporter, transmembrane K18890 - - 3.779e-205 660.0
HFD3_k127_7345015_4 ABC transporter, transmembrane K18889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 599.0
HFD3_k127_7345015_5 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006761 491.0
HFD3_k127_7345015_6 PFAM Glycosyl hydrolase family 10 K01181 - 3.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 401.0
HFD3_k127_7345015_7 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 379.0
HFD3_k127_7345015_8 ROK family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007524 339.0
HFD3_k127_7345015_9 PFAM Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007532 319.0
HFD3_k127_7351288_0 PFAM Sodium sulphate symporter K14445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 429.0
HFD3_k127_7351288_1 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000664 196.0
HFD3_k127_7351288_2 cell adhesion involved in biofilm formation K02014,K11031 - - 0.00000000000000000000000000000000000000002648 161.0
HFD3_k127_7352223_0 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 420.0
HFD3_k127_7352223_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009306 372.0
HFD3_k127_7352223_2 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003236 371.0
HFD3_k127_7352223_3 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009695 346.0
HFD3_k127_7352223_4 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003505 333.0
HFD3_k127_7352223_5 Peptidase dimerisation domain K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 293.0
HFD3_k127_7352223_6 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005329 286.0
HFD3_k127_7352223_7 Belongs to the DapB family K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000003289 217.0
HFD3_k127_7352223_8 Domain of unknown function (DUF4159) - - - 0.0000000000000000000000000000000000000000000004488 177.0
HFD3_k127_7352223_9 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000001585 92.0
HFD3_k127_7353992_0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01585 - 4.1.1.19 7.013e-299 930.0
HFD3_k127_7353992_1 efflux transmembrane transporter activity - - - 3.406e-236 764.0
HFD3_k127_7353992_10 Protein conserved in bacteria K20274 - - 0.00000000000000000000000000000000000000000000000002498 207.0
HFD3_k127_7353992_11 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000000000000000000002183 165.0
HFD3_k127_7353992_12 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.0000000000000000000000000000000000000009262 160.0
HFD3_k127_7353992_13 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000000000000000004048 142.0
HFD3_k127_7353992_14 Transglycosylase associated protein - - - 0.0000000000000000000000000002593 117.0
HFD3_k127_7353992_15 Amidohydrolase family - - - 0.00000000000000000000184 111.0
HFD3_k127_7353992_16 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000194 97.0
HFD3_k127_7353992_17 Alpha-2-Macroglobulin K06894 - - 0.00000000000008889 72.0
HFD3_k127_7353992_2 Peptidase family M28 - - - 9.575e-214 693.0
HFD3_k127_7353992_3 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008562 490.0
HFD3_k127_7353992_4 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003966 463.0
HFD3_k127_7353992_5 LytTr DNA-binding domain K02477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000321 283.0
HFD3_k127_7353992_6 Histidine kinase K08082 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000004878 271.0
HFD3_k127_7353992_7 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000001211 249.0
HFD3_k127_7353992_8 CARDB - - - 0.000000000000000000000000000000000000000000000000006243 209.0
HFD3_k127_7353992_9 Esterase-like activity of phytase - - - 0.000000000000000000000000000000000000000000000000007463 196.0
HFD3_k127_7359469_0 phosphorelay sensor kinase activity - - - 0.000000000000000000000000000000000000000000000001258 197.0
HFD3_k127_7359469_1 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02481,K07713 GO:0000156,GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0023052,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035556,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.0000000000000000000000000000001871 128.0
HFD3_k127_7359469_2 Uncharacterized ACR, COG1399 K07040 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.0000005519 57.0
HFD3_k127_7362881_0 COG0644 Dehydrogenases (flavoproteins) - - - 7.7e-211 662.0
HFD3_k127_7362881_1 Beta-L-arabinofuranosidase, GH127 K09955 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007107 625.0
HFD3_k127_7362881_10 pyrroloquinoline quinone binding - - - 0.000000000000000000000000000000000000000000004725 174.0
HFD3_k127_7362881_11 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000003389 173.0
HFD3_k127_7362881_12 GxxExxY protein - - - 0.0000000000000000000000000000007129 131.0
HFD3_k127_7362881_13 pyrroloquinoline quinone binding - - - 0.000000000000000000000000000009393 134.0
HFD3_k127_7362881_14 pyridoxamine 5-phosphate - - - 0.00000000000000000000000000003749 121.0
HFD3_k127_7362881_15 Thioesterase superfamily K07107 - - 0.000000000000000000000000121 110.0
HFD3_k127_7362881_17 Protein of unknown function with HXXEE motif - - - 0.00002046 53.0
HFD3_k127_7362881_18 Polymer-forming cytoskeletal - - - 0.0007114 47.0
HFD3_k127_7362881_2 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003111 621.0
HFD3_k127_7362881_3 COG0635 Coproporphyrinogen III oxidase and related Fe-S - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 503.0
HFD3_k127_7362881_4 pyridoxamine 5'-phosphate oxidase-related FMN-binding K07006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006309 404.0
HFD3_k127_7362881_5 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 312.0
HFD3_k127_7362881_6 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000004381 236.0
HFD3_k127_7362881_7 Domain of Unknown Function (DUF1206) - - - 0.0000000000000000000000000000000000000000000000000000000000001204 224.0
HFD3_k127_7362881_8 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000288 213.0
HFD3_k127_7362881_9 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.000000000000000000000000000000000000000000000000004691 197.0
HFD3_k127_7365843_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 572.0
HFD3_k127_7365843_1 Ribosomal RNA adenine dimethylases K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00000000000000000000000000000000000000000000000001231 190.0
HFD3_k127_7365843_2 Zincin-like metallopeptidase K00930 - 2.7.2.8 0.000000000000000000000001474 109.0
HFD3_k127_7365843_3 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins K03466 - - 0.0000002637 54.0
HFD3_k127_7384825_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009527 475.0
HFD3_k127_7384825_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 398.0
HFD3_k127_7384825_2 PFAM PfkB domain protein K00856 - 2.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005875 374.0
HFD3_k127_7384825_3 TIGRFAM LAO AO transport system ATPase K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 325.0
HFD3_k127_7384825_4 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009228 288.0
HFD3_k127_7384825_5 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000002438 175.0
HFD3_k127_7384825_6 von Willebrand factor, type A - - - 0.00000000000000000000000000000000000000004089 164.0
HFD3_k127_7384825_7 PFAM Glyoxalase bleomycin resistance protein dioxygenase K01759,K05606 - 4.4.1.5,5.1.99.1 0.0000000000000000000000000000000000000002047 154.0
HFD3_k127_7384825_8 - - - - 0.0000000000000000000347 100.0
HFD3_k127_7384825_9 Predicted membrane protein (DUF2085) - - - 0.0007743 49.0
HFD3_k127_7385464_0 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 0.0 1214.0
HFD3_k127_7385464_1 Uncharacterized protein conserved in bacteria (DUF2130) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001378 270.0
HFD3_k127_7385464_2 - - - - 0.00000000000000000000000000000000000000000000000000000001142 207.0
HFD3_k127_7385464_4 PIN domain - - - 0.000000000000000000000000000000000663 146.0
HFD3_k127_7385464_5 - - - - 0.0000000000000000000000000003201 121.0
HFD3_k127_7385464_6 efflux transmembrane transporter activity - - - 0.000000000000000000000003564 109.0
HFD3_k127_7385464_8 Pyridoxamine 5'-phosphate oxidase K07226 - - 0.0000000002904 67.0
HFD3_k127_7385464_9 Protein kinase domain K12132 - 2.7.11.1 0.0006046 45.0
HFD3_k127_7387083_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1110.0
HFD3_k127_7387083_1 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 531.0
HFD3_k127_7387083_10 Carbon dioxide concentrating mechanism carboxysome shell protein K04027 - - 0.000000000000000000000000000000000000003496 148.0
HFD3_k127_7387083_11 PFAM Transglycosylase SLT domain K08309 - - 0.000000000000000000000000000000000004629 145.0
HFD3_k127_7387083_12 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000004844 61.0
HFD3_k127_7387083_13 - - - - 0.00012 49.0
HFD3_k127_7387083_2 TIGRFAM acetaldehyde dehydrogenase (acetylating) K00132 - 1.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009899 495.0
HFD3_k127_7387083_3 Lysin motif K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 338.0
HFD3_k127_7387083_4 PFAM Type II secretion system F domain K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 300.0
HFD3_k127_7387083_5 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000001499 259.0
HFD3_k127_7387083_6 PFAM Type II secretion system protein E K02652 - - 0.000000000000000000000000000000000000000000000000000001423 198.0
HFD3_k127_7387083_7 Domain of unknown function (DUF4252) - - - 0.0000000000000000000000000000000000000000000002414 178.0
HFD3_k127_7387083_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000006066 188.0
HFD3_k127_7387083_9 Peptidase, M23 family - - - 0.00000000000000000000000000000000000000195 168.0
HFD3_k127_7396163_0 Calcineurin-like phosphoesterase K01077 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000008107 228.0
HFD3_k127_7396163_1 Pfam Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000004562 178.0
HFD3_k127_7396163_2 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000001097 93.0
HFD3_k127_7396163_3 Sulfatase - - - 0.0000009389 61.0
HFD3_k127_7407129_0 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 359.0
HFD3_k127_7407129_1 Cleaves the N-terminal amino acid of tripeptides K01258 - 3.4.11.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 356.0
HFD3_k127_7407129_2 ATP-dependent helicase K03579 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000519 306.0
HFD3_k127_7407129_3 BlaR1 peptidase M56 - - - 0.00000000000000000000000000000000000000000008105 181.0
HFD3_k127_7407129_4 - - - - 0.000000000000000000000000000000000008589 150.0
HFD3_k127_7407129_5 Penicillinase repressor - - - 0.000000000000000000000000000000009957 130.0
HFD3_k127_7407129_6 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00000000000000000182 97.0
HFD3_k127_7407129_7 tonb protein K03832 - - 0.000000002416 70.0
HFD3_k127_7453280_0 serine-type peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004319 392.0
HFD3_k127_7453280_1 Molybdate ABC transporter K02018 - - 0.0000000000000000000000000000000000000000000000000000000000000002372 233.0
HFD3_k127_7453280_2 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.29 0.00000000000000000000000000000000000000000000000000000001541 216.0
HFD3_k127_7453280_3 Bacterial extracellular solute-binding protein - - - 0.000000000000000000000000000003731 124.0
HFD3_k127_7482372_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 543.0
HFD3_k127_7482372_1 Sodium Bile acid symporter family K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 518.0
HFD3_k127_7482372_10 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.0000000000000000000000000000000000008712 140.0
HFD3_k127_7482372_11 Protein tyrosine kinase - - - 0.0000000000000000000000000000000001216 139.0
HFD3_k127_7482372_12 redox-active disulfide protein 2 - - - 0.0000000000000000000008817 98.0
HFD3_k127_7482372_13 PFAM amino acid-binding ACT domain protein - - - 0.0000000000005472 78.0
HFD3_k127_7482372_14 Transcriptional regulator K03892,K21903 - - 0.0000000008915 68.0
HFD3_k127_7482372_15 snoRNA binding - - - 0.00000293 54.0
HFD3_k127_7482372_2 Predicted permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 442.0
HFD3_k127_7482372_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797 381.0
HFD3_k127_7482372_4 Phosphoenolpyruvate phosphomutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005114 339.0
HFD3_k127_7482372_5 Domain of unknown function (DUF4010) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005928 289.0
HFD3_k127_7482372_6 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001641 271.0
HFD3_k127_7482372_7 pyrroline-5-carboxylate reductase activity K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000002939 238.0
HFD3_k127_7482372_8 Metal dependent phosphohydrolases with conserved 'HD' motif. K01139 - 2.7.6.5,3.1.7.2 0.00000000000000000000000000000000000000000000001631 177.0
HFD3_k127_7484391_0 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 554.0
HFD3_k127_7484391_1 domain, Protein - - - 0.00000000005474 72.0
HFD3_k127_7484391_2 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.00000000005806 73.0
HFD3_k127_7515449_0 PFAM amidohydrolase - - - 1.024e-231 731.0
HFD3_k127_7515449_1 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 295.0
HFD3_k127_7515449_2 MFS_1 like family K08151,K08153 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002578 287.0
HFD3_k127_7515449_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004183 291.0
HFD3_k127_7515449_4 Domain of Unknown Function (DUF349) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000495 293.0
HFD3_k127_7515449_5 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001375 284.0
HFD3_k127_7516691_0 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000007564 156.0
HFD3_k127_7516691_1 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K06187,K09747 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363 - 0.00000000000000000000000000002601 125.0
HFD3_k127_7516691_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000005824 57.0
HFD3_k127_7561619_0 OPT oligopeptide transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 336.0
HFD3_k127_7561619_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002502 261.0
HFD3_k127_7561619_2 Stress responsive A/B Barrel Domain - - - 0.000000000000000000001771 94.0
HFD3_k127_7582707_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 412.0
HFD3_k127_7582707_1 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 304.0
HFD3_k127_7582707_2 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000003644 117.0
HFD3_k127_7589482_0 Belongs to the UbiD family K03182 - 4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 602.0
HFD3_k127_7589482_1 Belongs to the ClpA ClpB family K03696 GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008077 509.0
HFD3_k127_7589482_10 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000009653 215.0
HFD3_k127_7589482_11 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000001707 190.0
HFD3_k127_7589482_12 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K07081,K11782,K11784 - 1.21.98.1,4.2.1.151 0.00000000000000000000000000000000000000000000000001017 192.0
HFD3_k127_7589482_13 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.0000000000000000000007149 111.0
HFD3_k127_7589482_14 TonB C terminal - - - 0.0000000007308 70.0
HFD3_k127_7589482_15 Outer membrane protein (OmpH-like) K06142 - - 0.000001146 58.0
HFD3_k127_7589482_2 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 413.0
HFD3_k127_7589482_3 TIGRFAM outer membrane protein assembly complex, YaeT protein K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006019 412.0
HFD3_k127_7589482_4 Udp N-acetylglucosamine O-acyltransferase; Domain 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006329 311.0
HFD3_k127_7589482_5 Protein of unknown function (DUF1009) K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003059 277.0
HFD3_k127_7589482_6 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001858 273.0
HFD3_k127_7589482_7 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000366 245.0
HFD3_k127_7589482_8 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000001444 235.0
HFD3_k127_7589482_9 Amidohydrolase family K20810 - 3.5.4.40 0.00000000000000000000000000000000000000000000000000000000000000001484 243.0
HFD3_k127_7611149_0 polysaccharide catabolic process K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 336.0
HFD3_k127_7611149_1 response to heat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002824 277.0
HFD3_k127_7611149_2 Domain of Unknown Function (DUF1259) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009371 271.0
HFD3_k127_7611149_3 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000003512 258.0
HFD3_k127_7611149_4 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000007929 197.0
HFD3_k127_7611149_5 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000000000000000005336 160.0
HFD3_k127_7611149_6 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000004068 119.0
HFD3_k127_7611149_7 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000002416 74.0
HFD3_k127_7611149_8 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000001562 65.0
HFD3_k127_7630362_0 tagaturonate epimerase - - - 3.149e-263 837.0
HFD3_k127_7630362_1 PFAM short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 417.0
HFD3_k127_7630362_2 D-galactarate dehydratase / Altronate hydrolase, C terminus K16850 - 4.2.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000001112 269.0
HFD3_k127_7630362_3 SAF K16849 - 4.2.1.7 0.0000000000000000000009722 98.0
HFD3_k127_7638902_0 alcohol dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 374.0
HFD3_k127_7638902_1 thiolester hydrolase activity K01179,K06889,K10773,K15853 - 3.2.1.4,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 328.0
HFD3_k127_7638902_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003645 307.0
HFD3_k127_7638902_3 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000001175 139.0
HFD3_k127_7638902_4 alcohol dehydrogenase - - - 0.0000002775 53.0
HFD3_k127_7651707_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 558.0
HFD3_k127_7651707_1 - - - - 0.00000000000000000000000002869 115.0
HFD3_k127_7680708_0 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 359.0
HFD3_k127_7680708_1 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002957 349.0
HFD3_k127_7680708_2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K07516 - 1.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 313.0
HFD3_k127_7680708_3 YsiA-like protein, C-terminal region K13770 - - 0.00000000000000000000000000000000000000008248 162.0
HFD3_k127_7680708_4 transcriptional K21600 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000001362 88.0
HFD3_k127_7717445_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 475.0
HFD3_k127_7717445_1 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000184 267.0
HFD3_k127_7717445_2 O-acyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000004374 233.0
HFD3_k127_7717445_3 - - - - 0.00000000000005025 83.0
HFD3_k127_7717445_4 DinB superfamily - - - 0.00008779 49.0
HFD3_k127_780624_0 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 555.0
HFD3_k127_780624_1 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000009107 156.0
HFD3_k127_780624_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.0000000000000000000000000000000000000003077 155.0
HFD3_k127_780624_3 AntiSigma factor - - - 0.000001247 56.0
HFD3_k127_780624_4 RNA polymerase K03088 - - 0.00001168 51.0
HFD3_k127_790287_0 MacB-like periplasmic core domain - - - 1.865e-296 931.0
HFD3_k127_790287_1 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000006904 213.0
HFD3_k127_790287_2 pfkB family carbohydrate kinase K18478 - 2.7.1.184 0.000000000000000000000000000000000000000000000000004712 193.0
HFD3_k127_790287_3 - - - - 0.00000000000000000000003491 108.0
HFD3_k127_790287_4 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000001795 71.0
HFD3_k127_790287_5 Protein of unknown function (DUF3617) - - - 0.000000000007552 68.0
HFD3_k127_790287_6 SMART Transport-associated and nodulation - - - 0.000000003518 65.0
HFD3_k127_803505_0 response regulator - - - 0.000000000000000000000000000000000000000000000000000000005776 206.0
HFD3_k127_803505_1 Histidine kinase - - - 0.0000000000000004263 88.0
HFD3_k127_803505_2 Y_Y_Y domain - - - 0.0000000005568 69.0
HFD3_k127_803505_3 Histidine kinase - - - 0.00003726 47.0
HFD3_k127_804070_0 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 414.0
HFD3_k127_804070_1 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000002164 210.0
HFD3_k127_804070_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00002573 54.0
HFD3_k127_804653_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K17050 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0042126,GO:0043436,GO:0043546,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0097159,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 0.0 1020.0
HFD3_k127_804653_1 lysine biosynthetic process via aminoadipic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 406.0
HFD3_k127_804653_2 Oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 355.0
HFD3_k127_804653_3 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000003256 228.0
HFD3_k127_804653_4 Cytochrome c - - - 0.0000000000000000000000000000002269 138.0
HFD3_k127_804653_5 PFAM Polysulphide reductase, NrfD K00185 - - 0.00000000000002194 83.0
HFD3_k127_817485_0 Domain of unknown function (DUF1998) K06877 - - 4.395e-270 856.0
HFD3_k127_817485_1 Sodium:alanine symporter family K03310 - - 0.000000000000000000000000000000000000000000001652 167.0
HFD3_k127_817485_2 RNase_H superfamily K07502 - - 0.00000000000000000000000000000000000000005532 174.0
HFD3_k127_832398_0 Transport of potassium into the cell K03549 - - 1.039e-239 757.0
HFD3_k127_832398_1 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005305 396.0
HFD3_k127_832398_2 Glycoside hydrolase family 16 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003458 310.0
HFD3_k127_832398_3 Uncharacterised protein family (UPF0182) K09118 - - 0.0000000000000002747 84.0
HFD3_k127_838610_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008197 401.0
HFD3_k127_838610_1 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 298.0
HFD3_k127_838610_10 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.00000000000000000002852 96.0
HFD3_k127_838610_11 MotA/TolQ/ExbB proton channel family K03561,K03562 - - 0.00000000003115 64.0
HFD3_k127_838610_12 HPr family K11189 - - 0.0000000117 63.0
HFD3_k127_838610_13 TonB C terminal K03832 - - 0.00001415 57.0
HFD3_k127_838610_2 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007685 297.0
HFD3_k127_838610_3 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.00000000000000000000000000000000000000000000000000000000000000000155 246.0
HFD3_k127_838610_4 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000000001837 171.0
HFD3_k127_838610_5 Mannose-6-phosphate isomerase - - - 0.000000000000000000000000000000000000000000005315 168.0
HFD3_k127_838610_6 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000003748 136.0
HFD3_k127_838610_7 PTS system fructose IIA component K02793 - 2.7.1.191 0.0000000000000000000000000212 113.0
HFD3_k127_838610_8 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.00000000000000000000000004121 113.0
HFD3_k127_838610_9 Outer membrane lipoprotein - - - 0.000000000000000000003481 104.0
HFD3_k127_841521_0 Beta-galactosidase trimerisation domain K12308 - 3.2.1.23 0.0 1047.0
HFD3_k127_841521_1 membrane organization K07277,K09800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 638.0
HFD3_k127_841521_10 - - - - 0.0000004838 62.0
HFD3_k127_841521_11 Lipid A 3-O-deacylase (PagL) - - - 0.0001122 54.0
HFD3_k127_841521_2 Enolase C-terminal domain-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004059 461.0
HFD3_k127_841521_3 Oxidoreductase family, C-terminal alpha/beta domain K13020 - 1.1.1.335 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004623 392.0
HFD3_k127_841521_4 SIS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005455 337.0
HFD3_k127_841521_5 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006256 293.0
HFD3_k127_841521_6 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004561 297.0
HFD3_k127_841521_7 Glycosyl hydrolase family 9 K01179 - 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000006033 246.0
HFD3_k127_841521_8 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000009556 232.0
HFD3_k127_841521_9 Glycosyl transferase family 41 - - - 0.00000008381 63.0
HFD3_k127_843300_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K00256 - 1.3.99.16 3.034e-213 694.0
HFD3_k127_843300_1 Protein of unknown function (DUF3500) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004343 440.0
HFD3_k127_843300_2 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 325.0
HFD3_k127_843300_3 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000000000000000000000000000003187 214.0
HFD3_k127_843300_4 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000006747 185.0
HFD3_k127_843300_5 nuclear chromosome segregation - - - 0.00000000000000000000000000000000000000000000000004858 194.0
HFD3_k127_843300_6 - - - - 0.000000000000000000000000000000000000000000000003986 179.0
HFD3_k127_843300_7 SWIB/MDM2 domain K03169 - 5.99.1.2 0.0000000000000000000000000000001549 127.0
HFD3_k127_843300_8 Glucose sorbosone - - - 0.000000000000000000000000000006068 139.0
HFD3_k127_851787_0 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008108 304.0
HFD3_k127_851787_1 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003542 305.0
HFD3_k127_851787_2 Surface antigen variable number - - - 0.000000000000000000000000000000000000000000000000000000000000000000002037 269.0
HFD3_k127_851787_3 PFAM glycosyl transferase family 39 - - - 0.000000000000000000000000000000000000000006356 173.0
HFD3_k127_851787_4 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation - - - 0.000000002402 68.0
HFD3_k127_855817_0 Lysin motif K19223 - - 0.000000000000000000000000000000000001348 159.0
HFD3_k127_855817_1 D-alanyl-D-alanine carboxypeptidase K07260 - 3.4.17.14 0.0000000006847 72.0
HFD3_k127_855817_2 SMART heat shock protein DnaJ domain protein K05801 - - 0.0008049 50.0
HFD3_k127_85723_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 2.102e-280 884.0
HFD3_k127_85723_1 Belongs to the HypD family K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 485.0
HFD3_k127_85723_10 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000003362 89.0
HFD3_k127_85723_11 LssY C-terminus - - - 0.00000002835 66.0
HFD3_k127_85723_12 EF-hand domain pair - - - 0.000003398 59.0
HFD3_k127_85723_13 - - - - 0.0009868 47.0
HFD3_k127_85723_2 hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 422.0
HFD3_k127_85723_3 Histone methylation protein DOT1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 328.0
HFD3_k127_85723_4 TIGRFAM Hydrogenase accessory protein HypB K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005758 278.0
HFD3_k127_85723_5 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000011 267.0
HFD3_k127_85723_6 beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001298 287.0
HFD3_k127_85723_7 PFAM peptidase M52 hydrogen uptake protein K03605 - - 0.0000000000000000000000000000000000002613 146.0
HFD3_k127_85723_8 Transcription factor zinc-finger - - - 0.000000000000000000000000001264 120.0
HFD3_k127_85723_9 carbon dioxide binding K04653,K04654 - - 0.000000000000000000000000004761 115.0
HFD3_k127_858233_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 453.0
HFD3_k127_858233_1 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007202 485.0
HFD3_k127_858233_2 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006114 372.0
HFD3_k127_858233_3 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007048 272.0
HFD3_k127_858233_4 Stationary phase survival protein, YicC family, YicC_N and DUF1732 domain-containing - - - 0.00000000000000000000000000000000000000000000000000372 193.0
HFD3_k127_858233_5 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000007157 169.0
HFD3_k127_858233_6 Belongs to the UDP-glucose GDP-mannose dehydrogenase family - - - 0.00000001737 55.0
HFD3_k127_858954_0 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000007823 234.0
HFD3_k127_858954_1 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000001101 186.0
HFD3_k127_858954_2 cytochrome C peroxidase - - - 0.0001355 51.0
HFD3_k127_865266_0 Belongs to the glycosyl hydrolase 31 family K01811 - 3.2.1.177 6.401e-315 1002.0
HFD3_k127_865266_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 6.873e-198 627.0
HFD3_k127_865266_10 Sugar (and other) transporter - - - 0.00000000000000000000000000000000002303 149.0
HFD3_k127_865266_11 OsmC-like protein K07397 - - 0.000000000000000000009564 102.0
HFD3_k127_865266_12 DNA-sulfur modification-associated - - - 0.0002824 54.0
HFD3_k127_865266_2 Methane oxygenase PmoA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006949 400.0
HFD3_k127_865266_3 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 407.0
HFD3_k127_865266_4 cobalamin-transporting ATPase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000044 351.0
HFD3_k127_865266_5 Belongs to the UPF0271 (lamB) family K07160 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 293.0
HFD3_k127_865266_6 Oxidoreductase NAD-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002578 270.0
HFD3_k127_865266_7 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000000009075 226.0
HFD3_k127_865266_8 high-affinity ferrous iron transmembrane transporter activity K07243 - - 0.0000000000000000000000000000000000000000000000000000002297 203.0
HFD3_k127_865266_9 Membrane - - - 0.00000000000000000000000000000000000000000004686 177.0
HFD3_k127_874837_0 thiamine kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 548.0
HFD3_k127_874837_1 Myo-inositol-1-phosphate synthase K01858 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 0.000000000000001256 87.0
HFD3_k127_888612_0 Peptidase S9, prolyl oligopeptidase active site domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 610.0
HFD3_k127_888612_1 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000714 525.0
HFD3_k127_888612_10 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000005027 130.0
HFD3_k127_888612_11 Periplasmic or secreted lipoprotein - - - 0.000000000008261 77.0
HFD3_k127_888612_2 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007416 494.0
HFD3_k127_888612_3 COG0534 Na -driven multidrug efflux pump K03327 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 432.0
HFD3_k127_888612_4 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 393.0
HFD3_k127_888612_5 Family of unknown function (DUF1028) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 335.0
HFD3_k127_888612_6 zinc metalloprotease K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 314.0
HFD3_k127_888612_7 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 302.0
HFD3_k127_888612_8 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000003618 222.0
HFD3_k127_888612_9 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000001756 206.0
HFD3_k127_892534_0 Penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 413.0
HFD3_k127_900727_0 pyrroloquinoline quinone binding K01206 - 3.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006789 362.0
HFD3_k127_900727_1 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000689 276.0
HFD3_k127_900727_10 PASTA - - - 0.00000000002345 78.0
HFD3_k127_900727_11 thiolester hydrolase activity - - - 0.00000001015 64.0
HFD3_k127_900727_13 Tetratricopeptide repeat - - - 0.0006009 54.0
HFD3_k127_900727_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000006817 231.0
HFD3_k127_900727_3 3-beta hydroxysteroid dehydrogenase/isomerase family K22252 - 1.1.1.135 0.0000000000000000000000000000000000000000000000000000000001448 228.0
HFD3_k127_900727_4 AAA-like domain - - - 0.000000000000000000000000000000000000000000000000006649 206.0
HFD3_k127_900727_5 CHAT domain - - - 0.0000000000000000000000000000000000000000000000001687 196.0
HFD3_k127_900727_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000004498 189.0
HFD3_k127_900727_7 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000001989 145.0
HFD3_k127_900727_8 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000001144 127.0
HFD3_k127_900727_9 domain protein - - - 0.000000000001109 71.0
HFD3_k127_917817_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1045.0
HFD3_k127_917817_1 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 549.0
HFD3_k127_917817_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 294.0
HFD3_k127_917817_3 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000003437 269.0
HFD3_k127_917817_4 Cobalamin B12-binding K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000007677 198.0
HFD3_k127_917817_5 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000002587 171.0
HFD3_k127_917817_6 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000004338 154.0
HFD3_k127_917817_7 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000002694 119.0
HFD3_k127_917817_8 outer membrane autotransporter barrel domain protein - - - 0.0005238 52.0
HFD3_k127_926930_0 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007979 488.0
HFD3_k127_926930_1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K02564 - 3.5.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 325.0
HFD3_k127_926930_2 symporter activity K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 312.0
HFD3_k127_926930_3 PFAM Xylose isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006632 299.0
HFD3_k127_926930_4 Amidohydrolase family K01443 - 3.5.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000003404 268.0
HFD3_k127_926930_5 Peptidase M48 - - - 0.00000000000000000000002294 116.0
HFD3_k127_946366_0 PFAM Radical SAM - - - 1.529e-233 732.0
HFD3_k127_946366_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008709 419.0
HFD3_k127_946366_2 Short-chain Dehydrogenase reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002957 240.0
HFD3_k127_946366_3 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000001498 184.0
HFD3_k127_946366_4 His Kinase A (phosphoacceptor) domain - - - 0.000000000009104 74.0
HFD3_k127_959193_0 PLD-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004884 345.0
HFD3_k127_971214_0 Alpha-amylase domain K05343 - 3.2.1.1,5.4.99.16 7.608e-243 760.0
HFD3_k127_971214_1 homoserine kinase activity K00823,K07250 - 2.6.1.19,2.6.1.22 2.088e-213 698.0
HFD3_k127_971214_10 Domain of unknown function (DUF1330) - - - 0.0000000000000000000000000001096 128.0
HFD3_k127_971214_13 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 0.00000001525 57.0
HFD3_k127_971214_14 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000004148 62.0
HFD3_k127_971214_15 toxin-antitoxin pair type II binding - - - 0.0001484 47.0
HFD3_k127_971214_2 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 1.908e-204 648.0
HFD3_k127_971214_3 ATP-dependent DNA helicase RecQ K03654 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 496.0
HFD3_k127_971214_4 Exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008792 432.0
HFD3_k127_971214_5 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 399.0
HFD3_k127_971214_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 315.0
HFD3_k127_971214_7 Amidinotransferase K01482 - 3.5.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004419 281.0
HFD3_k127_971214_8 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005473 288.0
HFD3_k127_971214_9 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000004178 230.0
HFD3_k127_972934_0 Glycosyl hydrolase family 9 - - - 0.0 1053.0
HFD3_k127_972934_1 transport - - - 4.046e-302 967.0
HFD3_k127_972934_10 PFAM Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 453.0
HFD3_k127_972934_11 ATP-dependent Clp protease adaptor protein ClpS - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 439.0
HFD3_k127_972934_12 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 407.0
HFD3_k127_972934_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006202 329.0
HFD3_k127_972934_14 Xylose isomerase domain protein TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009143 277.0
HFD3_k127_972934_15 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001578 273.0
HFD3_k127_972934_16 Thermolysin metallopeptidase, alpha-helical domain K01400 GO:0005575,GO:0005576 3.4.24.28 0.0000000000000000000000000000000000000000000000000000000000000000000002418 259.0
HFD3_k127_972934_17 Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000003258 247.0
HFD3_k127_972934_18 - - - - 0.00000000000000000000000000000000000000000000000000000000000000002643 250.0
HFD3_k127_972934_19 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000111 234.0
HFD3_k127_972934_2 oligopeptide transport K03305 - - 8.955e-210 664.0
HFD3_k127_972934_20 molybdenum ion binding K07140 - - 0.00000000000000000000000000000000000000000000000000000000000000241 224.0
HFD3_k127_972934_21 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000001373 216.0
HFD3_k127_972934_22 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.000000000000000000000000000000000000000000000000000000226 220.0
HFD3_k127_972934_23 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000002718 168.0
HFD3_k127_972934_24 Sigma-54 interaction domain K15836 - - 0.00000000000000000000000000000000000004571 158.0
HFD3_k127_972934_25 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000704 155.0
HFD3_k127_972934_26 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000000000000001554 137.0
HFD3_k127_972934_27 DoxX K16937 - 1.8.5.2 0.0000000000000000000000000000000001921 152.0
HFD3_k127_972934_28 hydroperoxide reductase activity K01607 - 4.1.1.44 0.000000000000000000000000000000153 125.0
HFD3_k127_972934_29 - - - - 0.00000000000000000000000000002303 129.0
HFD3_k127_972934_3 efflux transmembrane transporter activity - - - 2.356e-207 675.0
HFD3_k127_972934_31 Transcriptional regulator - - - 0.0008015 48.0
HFD3_k127_972934_4 PFAM glycoside hydrolase family 3 domain protein K05349 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006838 600.0
HFD3_k127_972934_5 PFAM oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 545.0
HFD3_k127_972934_6 peptidase activity K01266 - 3.4.11.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 508.0
HFD3_k127_972934_7 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 481.0
HFD3_k127_972934_8 dehydrogenases and related proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 466.0
HFD3_k127_972934_9 Alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008164 445.0
HFD3_k127_978446_0 PFAM Type II secretion system protein E K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 593.0
HFD3_k127_978446_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003407 569.0
HFD3_k127_978446_2 Type ii and iii secretion system protein K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006725 320.0
HFD3_k127_978446_3 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000000000000000000000000000001073 179.0
HFD3_k127_978446_4 Prokaryotic N-terminal methylation motif K02456 - - 0.00000000000000000000000000000002759 132.0
HFD3_k127_978446_5 general secretion pathway protein K02456,K02650 - - 0.000000000000000006329 96.0
HFD3_k127_978446_6 Pilus assembly protein K02662 - - 0.000000000002678 80.0
HFD3_k127_978446_7 PFAM Fimbrial assembly family protein K02663 - - 0.00000148 61.0
HFD3_k127_978446_8 Polymorphic membrane protein, Chlamydia - - - 0.00002071 57.0
HFD3_k127_978446_9 - - - - 0.0006705 49.0